Poster Presentations

Odd numbers: November 20 (Monday) 16:30-18:00
Even numbers: November 21 (Tuesday) 13:40–15:10

P-001

Reaction of sugar oxazolines with primary amines
Minoru Suda, Wataru Sumiyoshi, Takashi Kinoshita, Shoko Ohno (Fushimi Pharmaceutical Co. Ltd.)

P-002

Conformational studies on peptides having α,α-disubstituted α-amino acids with ()-menthyl skeleton
Suguru Matsumoto1, Atsushi Ueda1, Mitsunobu Doi2, Masakazu Tanaka1 (1Graduate School of
Biomedical Sciences, Nagasaki University, 2Osaka University of Pharmaceutical Sciences)

P-003

Synthesis of chiral three-membered ring α,α-disubstituted α-amino acid and conformational analysis of
its peptides
Yurie Koba, Hikaru Ikeda, Atsushi Ueda, Makoto Oba, Yosuke Demizu, Mitsunobu Doi, Masakazu
Tanaka (Graduate School of Biomedical Sciences Nagasaki University)

P-004

Development of chemical synthetic strategies for peptidomimetic based on a chloroalkene dipeptide
isostere and its application to a cyclic RGD peptide
Takuya Kobayakawa1, Wataru Nomura1, Kentaro Hozumi2, Motoyoshi Nomizu2, Hirokazu Tamamura1(1Institute of Biomaterials and Bioengineering, Tokyo Medical and Dental University, 2School of
Pharmacy, Tokyo University of Pharmacy and Life Sciences)

P-005

Biosynthesis of high molecular weight collagen-like artificial protein
Satoshi Yamada1, Seijiro Matsuki2, Yoshiaki Hirano2,3, Sachiro Kakinoki2,3 (1Graduate School of Scienceand Engineering Kansai University, 2Faculty of Chemistry, Materials and Bioengineering, Kansai
University, 3The Organization for Research and Development of Innovative Science and Technology,
Kansai University)

P-006

Secondary structures of homopeptides composed of cyclopentene-based amino acid
Haruka Yakabi1, Haruki Nakatani1, Makoto Oba2, Atsushi Ueda2, Mitsunobu Doi3, Masakazu Tanaka2(1Faculty of Pharmaceutical Sciences, Nagasaki University, 2Graduate School of Biomedical Sciences,
Nagasaki University, 3Osaka University of Pharmaceutical Sciences)

P-007

Asymmetric synthesis of α-deuterated α-amino acids
Ryosuke Takeda1,2, Hidenori Abe1, Norio Shibata3, Hiroki Moriwaki1, Kunisuke Izawa1, Vadim A.
Soloshonok2,4 (1Hamari Chemicals Ltd., 2Department of Organic Chemistry I, Faculty of Chemistry,
University of the Basque Country, 3Department of Nanopharmaceutical Sciences, and Department ofLife Science and Applied Chemistry, Nagoya Institute of Technology, 4IKERBASQUE, BasqueFoundation for Science)

P-008

Effects of salts and pH on coacervation of short elastin-like peptide (FPGVG)5
Daiki Tatsubo1, Misako Kodama1, Keiji Sato1, Keitaro Suyama2, Iori Maeda3, Takeru Nose1,2(1Department of Chemistry, Graduate School of Science, Kyushu University, 2Faculty of Arts andScience, Kyushu University, 3Department of Bioscience and Bioinformatics, Kyushu Institute ofTechnology)

P-009

The first synthesis of caged arginine and light control of caged peptides(8)Yoshiki Konda1, Ryosuke Sakamoto1, Gosuke Hayashi1, Akimitsu Okamoto1,2 (1The University ofTokyo, Graduate School of Engineering, 2The University of Tokyo, Research Center for Advanced
Science and Technology)
P-010

Synthesis and stability evaluation of new 3-nitro-2-pyridinesulfenate derivatives
Yan Cui, Cédric Rentier, Akihiro Taguchi, Kentaro Takayama, Atsuhiko Taniguchi, Yoshio Hayashi(Department of Medicinal Chemistry, Tokyo University of Pharmacy and Life Sciences)P-011

Peptide foldamers changing their conformations in response to low pH trigger
Kaori Furukawa1, Makoto Oba1, Kotomi Toyama1, Opiyo Geroge Ouma1, Yosuke Demise2, Masaaki
Kurihara3, Mitsunobu Doi4, Masakazu Tanaka1 (1Graduate School of Biomedical Sciences, Nagasaki
University, 2National Institute of Health Sciences, 3International University of Health and Welfare,
4

P-012

Osaka University of Pharmaceutical Sciences)

Synthetic study of cyclic disulfide peptide by using the solid-phase disulfide ligation method
Akihiro Taguchi, Yan Cui, Sahoko Fukumoto, Kiyotaka Kobayashi, Saeka Kuraishi, Kentaro Takayama,
Atsuhiko Taniguchi, Yoshio Hayashi (Department of Medicinal Chemistry, School of Pharmacy, Tokyo
University of Pharmacy and Life Sciences)P-013

Porphyrin-peptoid conjugates: controlled porphyrin interactions via peptoid structural change
Woojin Yang, Boyeong Kang, Jiwon Seo (Department of Chemistry, School of Physics and Chemistry,
Gwangju Institute of Science and Technology)

P-014

Porphyrin receptor: host-guest effect of chiral bis-(zinc porphyrin)-peptoid conjugate
Yen Jea Lee, Jiwon Seo (Department of Chemistry, Gwangju Institute of Science and Technology)

P-015

A facile method to construct azide- and cyanide-containing peptoids on resin
Dahyun Kang, Yen Jea Lee, Jiwon Seo (Department of Chemistry, School of Physics and Chemistry,
Gwangju Institute of Science and Technology)

P-016

Formation of oxopiperazine-containing peptoids through C-terminal cyclization
Yun Jee Lee, Jiwon Seo (Department of Chemistry, School of Physics and Chemistry, Gwangju Instituteof Science and Technology)

P-017

A facile method for preferential modification of the N-terminal amino group of peptides using DMTMM
Hironori Juichi, Atsushi Kitanaka, Yoichiro Nihashi, Masahiro Miyashita, Hisashi Miyagawa (Graduate
School of Agriculture, Kyoto University)

P-018

Construction of a hetero-dimeric macrocyclic peptide library for the discovery of peptide ligands thatinduce IL28RA-IL10RB hetero-dimerization
Satoshi Ishida, Takayuki Katoh, Hiroaki Suga (Graduate School of Science, The University of Tokyo)

P-019

Ralstonins A and B, unique lipopeptides synthesized by quorum sensing-dependent PKS-NRPS in
Ralstonia solanacearum
Yuta Murai1, Shoko Mori2, Hiroyuki Konno3, Yasufumi Hikichi4, Kenji Kai1 (1Graduate School of Lifeand Environmental Sciences, Osaka Prefecture University, 2Bioorganic Research Institute, Suntory
Foundation for Life Sciences, 3Graduate School of Science and Technology, Yamagata University,
4

P-020

Laboratory of Plant Pathology and Biotechnology, Kochi University)

Total synthesis and biological evaluation of PF1171B, D, E, and avellanins A, B, C
Masaya Honda, Yuichi Masuda (Graduate School of Bioresources, Mie University)

P-021

Total synthesis of neuroactive µ-conotoxin LT5D using two folding strategies(9)Ansyl Marie B. Naraga1, Oliver John V. Belleza1, Iris Bea L. Ramiro2, Abe Ernest Johann E. Isagan2,
Gisela P. Concepcion2, Aaron Joseph L. Villaraza1 (1Institute of Chemistry, University of the Philippines,
2

P-022

Marine Science Institute, University of the Philippines)

Isolation, purification, and characterization of bioactive peptides from the cone snail, Conus striolatus
Abe Ernest Johann E. Isagan1, Iris Bea L. Ramiro1, Ansyl Marie B. Naraga2, Oliver John V. Belleza2,
Julita S. Imperial3, Baldomero M. Olivera3, Aaron Joseph L. Villaraza2, Gisela P. Concepcion1 (1Marine
Science Institute, University of the Philippines, 2Institute of Chemistry, University of the Philippines,
3

P-023

Department of Biology, Salt Lake City, Utah, USA)

Isolation and chemical synthesis of a neuroactive peptide from Conus stercusmuscarum
Victor M. Chua1, Oliver John V. Belleza2, Ansyl Marie B. Naraga2, Julita S. Imperial3, Aaron Joseph L.
Villaraza2, Gisela P. Concepcion1 (1Marine Science Institute, College of Science, National Science
Complex, University of the Philippines, 2Institute of Chemistry, College of Science, National Science
Complex, University of the Philippines, 3Deparment of Biology, University of Utah)

P-024

Effects of novel peptide from fish elastin on cells
Kenji Miyanari1, Eri Shiratsuchi1, Mitsuki Takuno2, Takahito Komine2, Kazunari Arima2, Michio
Yamada1 (1Research & Development division, Hayashikane Sangyo Co., Ltd, 2Department of Chemistry
and Bioscience, Graduate School of Science and Engineering, Kagoshima University)

P-025

Existence and molecular forms of N-formylated peptide derived from cytochrome c oxidase subunit I
Toshihiro Shimizu, Tatsuya Hattori, Takayuki Martini, Yoshiaki Kiso, Hidehito Mukai (Laboratory ofPeptide Science, Graduate School of Bio-Science, Nagahama Institure of Bio-Science and Technology)

P-026

2,2'-Dipyridyl disulfide is an efficient deprotectant for N-terminal thiazolidine
Hidekazu Katayama, Satoki Morisue (Department of Applied Biochemistry, School of Engineering,
Tokai University)

P-027

Fast and cost effective solid phase synthesis of high quality crude peptides
Mandar Maduskar, Hossain Saneii, Mostafa Hatem, Farshad Karimi, Robert Obermann, William Bennett(AAPPTec LLC)

P-028

Microwave-assisted solid-phase synthesis of peptide-o-aminoanilide: scope and limitations
Shugo Tsuda, Tsuyoshi Uemura, Hideki Nishio, Yoshiya Taku (Peptide Institute, Inc.)

P-029

Evaluation of a new type thioester equivalent using intramolecular N-to-S acyl shift
Shugo Tsuda1, Masayoshi Mochizuki1, Ken Sakamoto1, Masaya Denda2, Hideki Nishio1, Akira Otaka2,
Taku Yoshiya1 (1Peptide Institute, Inc., 2Institute of Biomedical Sciences and Graduate School of
Pharmaceutical Sciences, Tokushima University)

P-030

Development of imidazole additive to accelerate native chemical ligation
Ken Sakamoto, Shugo Tsuda, Masayoshi Mochizuki, Yukie Nohara, Hideki Nishio, Taku Yoshiya(Peptide Institute, Inc.)

P-031

Development of peptide macrocyclization protocol utilizing o-aminoanilide linker for flow chemistry
Takumi Ohara, Masato Kaneda, Tomo Saito, Hiroaki Ohno, Shinya Oishi (Graduate School of
Pharmaceutical Sciences, Kyoto University)

P-032

Synthesis of glycopeptide using Boc group for the protection of carbohydrate hydroxyl groups
Tomohiro Tanaka, Mika Shiraishi, Reiko Sugihara, Akio Matsuda, Mamoru Mizuno (The Noguchi
Institute)

P-033

Development of methodology for producing thioesters from naturally occurring peptide sequences(10)Chiaki Komiya, Jun Tsukimoto, Takuya Morisaki, Yusuke Tsuda, Rin Miyajima, Tsubasa Inokuma,
Akira Shigenaga, Kohji Itoh, Akira Otaka (Institute of Health Biosciences and Graduate School of
Pharmaceutical Sciences, Tokushima University)
P-034

Appropriate quality control of middle molecular peptide API, depending on the purpose of use
Shunsuke Ochi, Yoshinori Murata (API R&D Center, CMC R&D Division, Shionogi & Co., LTD.)P-035

A novel N-protection-free ligation based on the thioester method
Hironobu Hojo1, Toru Kawakami1, Yuta Hiroyama2, Saburo Aimoto1 (1Institute for Protein Research,
Osaka University, 2Hamari Chemicals, Ltd.)

P-036

Investigation for the detection of peptides N-terminus on solid support
Rio Suzuki, Hiroyuki Konno (Department of Biochemical Engineering, Graduate School of Science andTechnology, Yamagata University)

P-037

Seamless cyclization of collagen-like peptides with Gly-X-Y-repeating sequences
Kazuki C. Kuroda, Fumiko Hisamatsu, Takaki Koide (Department of Chemistry and Biochemistry,
School of Advanced Science and Engineering, Waseda University)

P-038

Synthetic study for teixobactin
Kosuke Ohsawa1, Takuya Tokunaga1, Carys Thomas2, A. Ganesan2, Yuichi Masuda3, Takayuki Doi1
(1Graduate School of Pharmaceutical Sciences, Tohoku University, 2School of Pharmacy, University of
East Anglia, 3Graduate School of Bioresources, Mie University)

P-039

Two tandem-arrayed lysine residues play a key role in an allosteric peptide inhibitor binding to ERK2
Yurika Mori, Takayoshi Kinoshita (Graduate School of Science, Osaka Prefecture University)

P-040

Phenylalanine to cyclohexylalanine substitution inhibits amyloid formation by Alzheimer’s amyloid βpeptide
Mayumi Genji, Yoshiaki Yano, Masaru Hoshino, Katsumi Matsuzaki (Graduate School of
Pharmaceutical Sciences, Kyoto University)

P-041

Development of solid-phase synthesis protocol of coibamide A for the structure-activity relationshipstudy
Shinsaku Kawaguchi1, Kerry L. McPhail2, Shinsuke Inuki1, Hiroaki Ohno1, Shinya Oishi1 (1Graduate
School of Pharmaceutical Sciences, Kyoto University, 2College of Pharmacy, Oregon State University)

P-042

Phe2715.39 of thrombin receptor PAR-1 is a specific target of Phe-2-phenyl group of its tethered ligand
Makiko Sugiyama1, Tsugumi Fujita2, Xiaohui Liu1, Yutaka Matsuyama1, Ayami Matsushima1, Miki
Shimohigashi3, Yasuyuki Shimohigashi4 (1Department of Chemistry, Faculty and Graduate School of
Science, Kyushu University, 2Department of Physiology, Saga Medical School, 3Department of Earth
System of Science, Faculty of Science, Fukuoka University, 4Risk Science Project Laboratory, Kyushu
University)

P-043

Structure-activity relationship study for α-dystroglycan binding peptide A2G80 derived from mouselaminin α2 chain sequence
Fumihiko Katagiri, Yuka Fukasawa, Jun Kumai, Kentaro Hozumi, Yamato Kikkawa, Motoyoshi Nomizu(Department of Clinical Biochemistry, Tokyo University of Pharmacy and Life Sciences)P-044

In silico analysis strategy to explore the active conformers of cyclic peptides and docking to their
receptor
Akitoshi Okada, Yoshirou Kimura, Ryoichi Kataoka (Life Science Department, MOLSIS Inc.)

P-045

Development of cationic cell-penetrating peptides focused on their secondary structures(11)

Hiroyuki Kobayashi1,2, Takashi Misawa2, Makoto Oba3, Masakazu Tanaka3, Mikihiko Naito2, Kenji
Matsuno1, Yosuke Demizu2 (1School of Advanced Engineering, Kogakuin University, 2Division ofOrganic Chemistry, National Institute of Health Sciences, 3Graduate School of Biomedical Sciences,
Nagasaki University)
P-046

Development of post functionalizable oligopeptides as helical templates
Takashi Misawa, Yosuke Demizu (Division of Organic Chemistry, National Institute of Health Sciences)

P-047

Structure-hydrogelation relationship of self-assembling peptides with urea bond toward cell scaffold
material
Iori Kodama, Hisakazu Mihara, Hiroshi Tsutsumi (School of Life science and Technology, Tokyo
Institute of Technology)

P-048

Proline residue promotes selfassociation of transmembrane helices
Jun Uehara, Yoshiaki Yano, Katsumi Matsuzaki (Graduate School of Pharmaceutical Sciences, Kyoto
University)

P-049

Comparison of proteolytic activity of 5-mer peptides derived from box A domain of Tob/BTG family
proteins
Yusuke Hatakawa1, Rina Nakamura2, Masanari Taniguchi1, Motomi Konishi1, Toshifumi Akizawa1,2(1Laboratory of Clinical Analytical Chemistry, Faculty of Pharmaceutical Sciences, Setsunan University,
2

P-050

O-force Co. Ltd.)

Characterization of the Ca2+-coordination structures of T- and L-plastins by infrared spectroscopy in
combination with synthetic peptide analogue
Masayuki Nara1, Hisayuki Morii1,2, Takashi Shimizu2, Hiroto Shinomiya3, Yuka Furuta4, Kenichi
Miyazono4, Takuya Miyakawa4, Masaru Tanokura4 (1College of Liberal Arts and Sciences, Tokyo
Medical and Dental University (TMDU), 2National Institute of Advanced Industrial Science andTechnology (AIST), 3Department of Medicine, Ehime University, 4Graduate School of Agricultural andLife Sciences, University of Tokyo)

P-051

Design of programmable pore-forming model using β-sheet peptides
Keisuke Shimizu1, Naoki Saigo1, Yusuke Sekiya1, Shungo Sakashita2, Yoshio Hamada2, Kenji Usui2,
Ryuji Kawano1 (1Department of Life Science and Biotechnology, Tokyo University of Agriculture andTechnology, 2Department of Nanobiochemistry, Konan University)

P-052

Can peptide deformylase produces methionine aminopeptidase inhibitors from their formylatedprecursors?
Yukari Oishi1, Yuri Takami1, Junichi Taira2, Hiroaki Kodama1, Satoshi Osada1 (1Department ofChemistry and Applied Chemistry, Faculty of School and Engineering, Saga University, 2Department of
Bioscience and Bioinformatics, Kyushu Institute of Technology)

P-053

Channel current measurement and analysis for programmable designs of stable pore-forming alphahelical peptides in lipid bilayer
Yusuke Sekiya, Ryuji Kawano (Department of Biotechnology and Life Science, Tokyo University ofAgriculture and Technology)

P-054

Analysis of membrane permeation activity of cellpenetrating peptides using channel current
measurements(12)

Naoki Saigo1, Yusuke Sekiya1, Akira Ishiguro2, Yukihito Ishizaka2, Ryuji Kawano1 (1Department of Life
Science and Biotechnology, Tokyo University of Agriculture and Technology,2

Department ofIntractable Diseases, National Center for Global Health and Medicine)
P-055

Design of plasmin inhibitor with targeting the S2’ subsite
Seika Sugiura1, Koushi Hidaka1,2, Keiko Hojo1,2, Keigo Gohda3, Naoki Teno4, Keiko Wanaka5, Yuko
Tsuda1,2 (1Faculty of Pharmaceutical Sciences, Kobe Gakuin University, 2Cooperative Research Centerof Life Sciences, Kobe Gakuin University, 3Computer-Aided Molecular Modeling Research Center,
Kansai, 4Faculty of Clinical Nutrition, Hiroshima International University, 5Research Projects on
Thrombosis and Haemostasis)

P-056

Interaction detail between sugar chain on HSV-1 glycoprotein with immune receptor PILRα
Takao Nomura1, Kosuke Kakita2, Atsushi Furukawa3, Masahiro Anada2, Shunichi Hashimoto2, Shigeki
Matsunaga2, Takashi Saitoh4, Katsumi Maenaka1,3 (1Center for Research and Education on Drug
Discovery, Faculty of Pharmaceutical Sciences, Hokkaido University, 2Laboratory of Synthetic andIndustrial Chemistry, Faculty of Pharmaceutical Sciences, Hokkaido University,

3

Laboratory of4

Biomolecular Science, Faculty of Pharmaceutical Sciences, Hokkaido University, School of Pharmacy,
Hokkaido Pharmaceutical University)
P-057

Comprehensive phylogeny-based analysis for molecular evolution of p53 family proteins
Fuki Kudoh, Natsumi Nakagawa, Rui Kamada, Kazuyasu Sakaguchi (Laboratory of Biological
Chemistry, Department of Chemistry, Faculty of Science, Hokkaido University)

P-058

Correlation between transcriptional activity and tetrameric structure stability of vertebrate p53
proteins
Natsumi Nakagawa, Junya Wada, Toshiaki Imagawa, Rui Kamada, Kazuyasu Sakaguchi (Laboratory of
Biological Chemistry, Department of Chemistry, Faculty of Science, Hokkaido University)

P-059

Novel methods for blocking amyloidogenesis of prion protein (180–193)
Ikumi Shibatate1, Tomomi Ueda1, Hisayuki Morii2, Misaki Kinoshita3, Young-Ho Lee3, Shinji
Hashimoto1, Masatoshi Saiki1 (1Faculty of Engineering, Tokyo University of Science, Yamaguchi,
2

College of Liberal Arts and Sciences, Tokyo Medical and Dental University, 3Institute for Protein

Research, Osaka University)
P-060

Mitocryptide-2: ligand recognition mechanisms of formyl-peptide receptor 1 and its homologue
formyl-peptide receptor 2
Kodai Nishino, Takayuki Marutani, Tatsuya Hattori, Yoshiaki Kiso, Hidehito Mukai (Laboratory ofPeptide Science, Graduate School of Bio-Science, Nagahama Institute of Bio-Science and Technology)

P-061

Structure-activity relationship of the G-CSF receptor binding peptides
Ayana Oshima, Asako Yamaguchi-Nomoto, Ikuo Fujii (Department of Biological Science, Graduate
School of Science, Osaka Prefecture University)

P-062

Identification of dipeptidic inhibitors targeting DPP7 derived from multiple drug resistant bacteria
Stenotrophomonas maltophilia
Yuki Sakurai1, Koushi Hidaka1,2, Anna Miyazaki1,2, Keiko Hojo1,2, Saori Roppongi3, Yasumitsu
Sakamoto3, Yasuhiro Ito4, Yoshiyuki Suzuki4, Wataru Ogasawara4, Nobutada Tanaka5, Yuko Tsuda1,2(1Faculty of Pharmaceutical Sciences, Kobe Gakuin University, 2Cooperative Research Center for Life
Sciences, Kobe Gakuin University, 3School of Pharmacy, Iwate Medical University, 4Department of
Bioengineering, Nagaoka University of Technology, 5School of Pharmacy, Showa University)(13)

P-063A helix-loop-helix peptide inhibiting intracellular p53-HDM2 interaction: a role of poly Arg in noninteracting surface of the N-terminal helix
Shunsuke Inaura, Hidekazu Kitada, Kazunori Zikihara, Daisuke Fujiwara, Ikuo Fujii (Department of
Biological Science, Graduate School of Science, Osaka Prefecture University)

P-064

Synthesis and structural investigation of cyclosporin A and cyclosporin O
Dongjae Lee, Sungjin Lee, Chin-ju Park, Jiwon Seo (Department of Chemistry, School of Physics andChemistry, Gwangju Institute of Science and Technology)

P-065

Development of anti-HER2 antibody mimetics with structually constrained CDR peptides
Wanaporn Yimchuen1, Tetsuya Kadonosono1, Kyra See1, Tadaomi Furuta2, Takahiro Kuchimaru1,
Shinae Kondoh1 (1School of Life Science and Technology, Tokyo Institute of Technology, 2Center for
Biological Resources and Informatics, Tokyo Institute of Technology)

P-066

Immunogenicity of a FAP2 peptide mimotope of Fusobacterium nucleatum and its use in an
immunoassay-based diagnostics tool for colorectal cancer
Leonardo A. Guevarra Jr.1,4, Andrea Claudine F. Afable1, Patricia Joyce O. Belza1, Karen Joy S. Dy1,
Scott Justin Q. Lee1, Teresita Ortin-Sy3, Pia Marie Albano2,4 (1Department of Biochemistry, Faculty of
Pharmacy, University of Santo Tomas, 2Department of Biology, College of Science, University of Santo
Tomas, 3Benavidez Cancer Institute, University of Santo Tomas, 4Research Center for Natural andApplied Sciences, University of Santo Tomas)

P-067

Actions of orexin B on spontaneous inhibitory synaptic transmission in adult rat spinal superficial
dorsal horn neurons
Chong Wang, Tsugumi Fujita, Nobuya Magori, Rika Suzuki, Fan Yang, Eiichi Kumamoto (Departmentof Physiology, Saga Medical School)

P-068

Cellular effects of artificial ubiquitin ligases on cancer cells
Mayumi Sunagawa, Ayumi Yamashita, Kazuki Saito, Kazuhide Miyamoto (Pharmaceutical Sciences,
Himeji Dokkyo University)

P-069

Intracellular delivery of bioactive proteins using endosome destabilizing peptide L17E
Misao Akishiba1, Toshihide Takeuchi1, Yoshimasa Kawaguchi1, Kentarou Sakamoto, Ikuhiko Nakase2,
Shiroh Futaki1 (1Institute for Chemical Research, Kyoto University, 2Nanoscience and Nanotechnology
Research Center, Research Organization for the Twenty First Century, Osaka Prefecture University)

P-070

Creation of high performance antibody drug alternatives harvoring constrained CDR peptides
Tetsuya Kadonosono1, Yumi Ota1, Wanaporn Yimchuen1, Kyra See1, Tadaomi Furuta2, Takahiro
Kuchimaru1, Shinae Kondoh1 (1School of Life Science and Technology, Tokyo Institute of Technology,
2

P-071

Center for Biological Resources and Informatics, Tokyo Institute of Technology)

Synthesis and biological evaluation of medium-chain alkyl sulfoniododecaborate containing pboronophenylalanine
Yoshihide Hattori1, Miki Ishimura1, Youichirou Ohta1, Hiroshi Takenaka1, Kouki Uehara2, Tomoyuki
Asano2, Mitsunori Kirihata1 (1Research Center of BNCT, Osaka Prefecture University, 2Stella Pharma
Co.)

P-072

Lysine-specific demethylase 1 inhibitory activity of histone H3 peptides incorporating modified lysine 4
Taeko Kakizawa1, Yosuke Ota2, Yukihiro Itoh2, Takayoshi Suzuki2 (1Department of Chemistry andBiochemistry, School of Advanced Science and Engineering, Waseda University, 2Graduate School of
Medical Science, Kyoto Prefectural University of Medicine)(14)

P-073Novel antimicrobial/anti-inflammatory peptides designed from human LL-37 with therapeuticpotential
Ganesan Rajasekaran1, Song Yub Shin1,2 (1Department of Biomedical Science, Graduate School, Chosun
University, 2Department of Cellular & Molecular Medicine, School of Medicine, Chosun University)

P-074

Cell selectivity and anti-inflammatory activity of the D-amino acid substituted derivatives of LL-37derived short antimicrobial peptide KR-12-A5
Song Yub Shin (Department of Cellular & Molecular Medicine, School of Medicine, Chosun University)

P-075

Antimicrobial activity of endosome destabilizing peptide L17E and some analogues
Naoki Tamemoto, Misao Akishiba, Kentarou Sakamoto, Jun Kawamoto, Tatsuo Kurihara, Shiroh Futaki(Institute for Chemical Research, Kyoto University)

P-076

Discovery of novel peptide ligand for nucleolin (NCL) overexpressed cancer cell
Jae-hyun Kim, Kyeong-min Kim, Young-Joon Kim, Zee Yong Park, Jae Il Kim (Department of Life
Science, Gwangju Institute of Science and Technology)

P-077

Development of HER2-targeting small protein harboring a structurally constrained peptide
Yumi Ota1, Tetsuya Kadonosono1, Takahiro Kuchimaru1, Masumi Taki2, Yuji Ito3, Shinae Kondoh1(1School of Life Science and Technology, Tokyo Institute of Technology, 2Department of Engineering
Science, the Graduate School of Informatics and Engineering, the University of Electro-Communications(UEC), 3Department of Chemistry and Bioscience, Graduate School of Science and Engineering,Kagoshima University)

P-078

Btk kinase inhibitor study using 3D-QSAR and molecular dynamics simulations
Seung Joo Cho1,2 (1Chosun University, 2Department of Cellular and Molecular Medicine, College ofMedicine, Chosun University)

P-079

Structure-activity relationship study of MAP(Aib)-cRGD conjugates as carriers for siRNA delivery
Shun-ichi Wada, Anna Takesada, Eri Sogabe, Rieko Ohki, Aki Kawakita, Junsuke Hayashi, Hidehito
Urata (Osaka University of Pharmaceutical Sciences)P-080

Cyclosporine A-loaded nano-matrix particles prepared with multi-inlet vortex mixer for inhalation
Hideyuki Sato1, Hiroki Suzuki1, Keisuke Yakushiji1, Jennifer Wong2, Yoshiki Seto1, Robert K.
Prud’homme3,

Hak-KimChan2,

Onoue1

Satomi(1Department

ofPharmacokinetics

and2

Pharmacodynamics, University of Shizuoka, Advanced Drug Delivery Group, Faculty of Pharmacy,
The University of Sydney, 3Department of Chemical & Biological Engineering, Princeton University)
P-081

Development of fluorescence-quenched substrate for discovering antibodies capable of hydrolyzing tau
protein
Hiroaki Taguchi1, Yasuhiro Ishihara1, Yoshio Fujita1, Emi Hifumi2, Taizo Uda3,4 (1Faculty of
Pharmaceuticals Sciences, Suzuka University of Medical Science, 2Research Promotion Institute, Oita
University, 3Faculty of Engineering, Oita University, 4Institute of Systems, Information Technologies
and Nanotechnologies)

P-082

Identification of receptor molecules for mitocryptide-3, a novel neutrophil-activating peptide derived
from mitochondrial transit sequence
Takayuki Marutani, Shinichiro Tamura, Kenta Nakashima, Kodai Nishino, Hiroki Morikawa, Tatsuya
Hattori, Yoshiaki Kiso, Hidehito Mukai (Laboratory of Peptide Science, Graduate School of Bio-Science,
Nagahama Institute of Bio-Science and Technology)(15)

P-083

Identification of laminin α5 short arm peptides active for endothelial cell attachment and tube
formation
Xiao Yang, Yumika Sugawara, Nozomi Harashima, Shogo Fujii, Kazuki Ikari, Jun Kumi, Fumihiko
Katagiri, Kentaro Hozumi, Yamato Kikkawa, Motoyoshi Nomizu (Department of Clinical Biochemistry,
School of Pharmacy, Tokyo University of Pharmacy and Life Sciences)

P-084

Novel water-soluble prodrug of β-secretase inhibitor as an anti-Alzheimer’s disease drug
Yoshio Hamada, Kenji Usui (Faculty of Frontiers of Innovative Research in Science and Technology(FIRST), Konan University)

P-085

Lysosome-targeting drug delivery system using the H16 peptide-modified liposome
Taiki Hayashi, Tsuyoshi Kawano, Takashi Iwasaki (Graduate School of Sustainability Science, Tottori
University)

P-086

Construction of bispecific antibody by site-specific chemical conjugation with IgG-binding peptide
Satoshi Kishimoto, Abdor Rafique, Kanade Fujisaki, Nobuyuki Nagamizo, Dai-ichiro Kato, Yuji Ito(Department of Chemistry and Bioscience, Graduate School of Science and Engineering, Kagoshima
University)

P-087

Mitocryptide-1: investigation of pathophysiological roles of mitocryptide-1 utilizing its specificneutralizing monoclonal antibody
Hiroki Morikawa, Tatsuya Hattori, Yoshito Takamuro, Takayuki Marutani, Yoshiaki Kiso, Hidehito
Mukai (Graduate School of Bio-Science, Nagahama Institute of Bio-Science and Technology)

P-088

Diclofenac-loaded cross-linked polylysine for sustained-release with reduced gastric damage
Aiko Tabata, Tatsuki Hirano, Ayaka Daicho, Yoshiki Seto, Hideyuki Sato, Satomi Onoue (Departmentof Pharmacokinetics and Pharmacodynamics, School of Pharmaceutical Sciences, University of
Shizuoka)

P-089

Antibacterial mechanism of pleurocidin peptide via apoptosis-like death in Escherichia coli
Lee Bin, Lee Dong Gun (School of Life Sciences, BK 21 Plus KNU Creative BioResearch Group,
College of Natural Sciences, Kyungpook National University)

P-090

A mechanism for the antibacterial effect of arenicin-1 on Escherichia coli
Lee Heejeong, Lee Dong Gun (School of Life Sciences, BK 21 Plus KNU Creative BioResearch Group,
College of Natural Sciences, Kyungpook National University)

P-091

Rational design of KRAS-SOS1 interaction inhibitor using helix-loop-helix peptide scaffold
Kousuke Mihara1,2, Daisuke Fujiwara1, Ikuo Fujii1 (1Department of Biological Science, Osaka Prefecture
University, 2Medicinal Chemistry Research Laboratory, Shionogi & Co., Ltd.)

P-092

Identification of α-dystroglycan binding sequence in the laminin α2 chain LG4-5 module using peptidechitosan matrix ELISA method
Guangrui Zhang, Jun Kumai, Kazuki Ikari, Xiao Yang, Yumika Sugawara, Fumihiko Katagiri, Kentaro
Hozumi, Yamato Kikkawa, Motoyoshi Nomizu (School of Pharmacy, Tokyo University of Pharmacy
and Life Sciences)

P-093

Design and synthesis of hydrocarbon stapling peptide antagonists for relaxin family peptide receptor 3(RXFP3)
Keiko Hojo1, Mika Izutsu1, Ross AD Bathgate2, K Johan Rosengern3, Koushi Hidaka1, Yuko Tsuda1,
Mohammad A Hossain2,4, John D Wade1,4 (1Faculty of Pharmaceutical Sciences, Kobe Gakuin(16)University, 2Florey Neuroscience Institute and Mental Health, University of Melbourne, 3School of
Biomedical Sciences, University of Queensland, 4School of Chemistry, University of Melbourne)
P-094

Synthesis and characterization of radiobromine-labeled bioactive peptides for molecular imaging
Keiichi Yamada1, Shigeki Watanabe2, Ichiro Sasaki1,2, Hirofumi Hanaoka3, Noriko S. Ishioka2 (1Divisionof Molecular Science, Gunma University, 2Department of Radiation-applied Biology, National Institutes
for Quantum and Radiological Science and Technology, 3Graduate School of Medicine, Gunma
University)

P-095

Efficient cellular uptake of the EGFR juxtamembrane domain peptide and its effects on receptor
activation
Ayaka Sugiyama1,2, Takeshi Sato3, Ikuhiko Nakase2 (1College of Life, Environment, and Advanced
Sciences, Osaka Prefecture University, 2NanoSquare Research Institution, Osaka Prefecture University,
3

P-096

Division of Liberal Arts Sciences, Kyoto Pharmaceutical University)

Construction of hydrocarbon stapled cellpenetrating peptides to deliver short RNAs
Soonsil Hyun1, Changjin Lee2, Yan Lee3, Jaehoon Yu1 (1Department of Chemistry & Education, Seoul
National University, 2Hugel, Inc., 3Department of Chemistry, Seoul National University)

P-097

A question revisited; Do lysozyme have a correlated antimicrobial activity with its enzymatic activity
against gram-negative bacteria?
Doyeon Jo, Soonsil Hyun, Jaehoon Yu (Department of Chemistry & Education, Seoul National
University)

P-098

Pyrrole-based small-molecule inhibitors targeting oocyte maturation
Pethaiah Gunasekaran, Jeong Kyu Bang (Division of Magnetic Resonance, Korea Basic Science
Institute)

P-099

Detection of E2 activities in cancer cells using an artificial E3 ligase
Ayumi Yamashita, Kazuki Saito, Kazuhide Miyamoto (Pharmaceutical Sciences, Himeji Dokkyo
University)

P-100

Cellular internalization mechanisms of all-hydrocarbon stapled peptides
Koki Sakagami, Shiroh Futaki (Institute for Chemical Research, Kyoto University)

P-101

Approach to control cell movement by changing membrane tension
Toshihiro Masuda, Tomo Murayama, Shiroh Futaki (Institute for Chemical Research, Kyoto University)

P-102

Novel macropinocytosis-inducing cell penetrating peptides
Jan Vincent V. Arafiles, Kenichi Kawano, Shiroh Futaki (Institute for Chemical Research, Kyoto
University)

P-103

A stapled α-helix peptide library displayed on phage for screening of peptide ligands binding togalectin-3
Teerapat Anananuchatkul1, Iou Ven Chang2, Hiroshi Tsutsumi1, Hisakazu Mihara1 (1Department of
Bioengineering, School of Life Science and Technology, Tokyo Institute of Technology, 2Graduate
School of Bioscience and Biotechnology, Tokyo Institute of Technology)

P-104

Structural-based design of a monosaccharide-modified α-helix peptide library for selective ligands tocarbohydrate-binding proteins by a phage display method
Iou Ven Chang1, Hisakazu Mihara1,2, Hiroshi Tsutsumi1,2 (1Department of Bioengineering, Graduate
School of Bioscience and Biotechnology, Tokyo Institute of Technology, 2Life Science and Technology,
Tokyo Institute of Technology)(17)

P-105Development of artificial bleomycin analogue: Pentadentate carboxamide ligand having spermine
moiety for DNA binding
Akiko Nomura1, Ryosuke Sakai2, Yuji Iwamoto2, Masahito Kodera2, Yutaka Hitomi2 (1Research Center
for Nano-Bioscience Research, Doshisha University, 2Department of Applied Chemistry, Graduate
School of Science and Engineering, Doshisha University)

P-106

Development of rat heme oxygenase-1 based gene encoded heme probe for intracellular heme detection
Junichi Taira, Otomi Nakashima, Hideyuki Komatsu, Hiroshi Sakamoto (Department of Bioscience andBioinformatics, Graduate School of Computer Science and Systems Engineering, Kyushu Institute ofTechnology)

P-107

Substrate recogntion of L-type amino acid transporter 3 (LAT3)
Toru Oba1, Rino Iwakami1, Kota Miyata1, Promsuk Jutabha2, Naohiko Anzai2,3 (1Department of Materialand Environmental Chemistry, Graduate school of Engineering, Utsunomiya University, 2Department ofPharmacology and Toxicology, Dokkyo Medical University School of Medicine, 3Department ofPharmacology, Chiba University Graduate School of Medicine)

P-108

Development and evaluation of cell-penetrating peptides having cyclic disubstituted amino acids
Takuma Kato1,2, Makoto Oba1, Masakazu Tanaka1 (1Graduate School of Biomedical Sciences, Nagasaki
University, 2Osaka University of Pharmaceutical Sciences)P-109

Identification of plasminogen-binding and -activation sequences in Plasmodium falciparum enolase:
Implication for the parasite invasion mechanism into the host cell
Hiroyuki Oku, Nana Isomoto, Yudai Kimoto, Shinya Kitamura, Keiichi Yamada, Kazuo Shinozuka(Division of Molecular Science, Graduate School of Science and Engineering, Gunma University)

P-110

Epigenetic analysis of histone H2A-H2B dimer powered by protein chemical synthesis
Gosuke Hayashi1, Takuma Sueoka1, Akimitsu Okamoto1,2 (1Department of Chemistry and Biotechnology,
The University of Tokyo, 2RCAST, The University of Tokyo)

P-111

In vitro selection of macrocyclic peptides binding covalently to a target protein
Naoya Ozawa, Yuki Goto, Hiroaki Suga (Department of Chemistry, Graduate School of Science, The
University of Tokyo)

P-112

Antioxidative activities of caffeoyl-prolyl-histidyl-Xaa tripeptides
Hyeri Jung1, Seojung Kim1, Jaehi Kim2, Dong-Sik Shin1, Yoon-Sik Lee2 (1Department of Chemical andBiological Engineering, College of Engineering, Sookmyung Women’s University, 2School of Chemical
and Biological Engineering, College of Engineering, Seoul National University)

P-113

Cell micropatterning on hydrogel for single cell protease detection
Da-Young Youn, Kyoung Eun Park, Dong-Sik Shin (Department of Chemical & Biological Engineeringand Department of Medical & Pharmaceutical Sciences, Sookmyung Women’s University)

P-114

Development of novel amyloid β peptide-binding compounds based on the alkene-to-amide isostericswitch stragety
Tomoyuki Imai, Kohei Sato, Nobuyuki Mase, Tetsuo Narumi (Graduate School of Integrated Scienceand Technology, Shizuoka University)

P-115

Synthesis of VEGF-targeting helix-loop-helix peptide-monomethyl auristatin E conjugate
Haruna Yamashita, Masakata Michigami, Ikuo Fujii (Department of Biological Science, Graduate
School of Science, Osaka Prefecture University)

P-116

A versatile method for modifying in vitro displayed macrocyclic peptide(18)

Shiori Umemoto, Seino A. Jongkees, Hiroaki Suga (Graduate School of Science, University of Tokyo)
P-117

Screening of peptide tag for selective protein labeling with zinc complex and its application to
fluorescence bioimaging
Nobutaka Kurashige1, Hirokazu Fuchida1, Shigekazu Tabata2, Shohei Uchinomiya1, Akio Ojida1(1Graduate School of Pharmaceutical Sciences, Kyushu University, 2Institute of Science and Technology
Austria)

P-118

Oral administlation of geniposidic acid may induce secretion of atrial natriuletic peptide in
spontaneously hypertensive rats
Shohei Yamaguchi1, Shingo Hosoo2, Masahiro Koyama1, Ryo Yamazaki1, Tetsuya Hirata2, Yasuyo
Yamaguchi2, Hiroo Yamasaki2, Naoto Minamino3, Keiji Wada4, Sansei Nishibe4, Kozo Nakamura1(1Department of Bioscience and Biotechnology, Faculty of Agriculture, Shinshu University, 2R&D
Center, Kobayashi Pharmaceutical Co., Ltd,
Cardiovascular Center,

43

Omics Research Center, National Cerebral andDepartment of Pharmaceutical Sciences, Health Sciences University of

Hokkaido)
P-119

Fish-derived collagen peptides improve maintenance of cultured human dermal fibroblasts
Masayo Kimura1, Ikurou Tanaka1, Tsutomu Nozaki1, Ryo Akimoto1, Ken-o Ishihara1, Hiroyuki Fujita2,
Toshio Nishiyama3 (1BHN Co., Ltd., 2Faculty of Bioenviromental Science, Kyoto Gakuen Univerity,
3

Scleroprotein Research Institute, Faculty of Agriculture, Tokyo University of Agriculture andTechnology)
P-120

Identifying antibacterial target(s) of the repositioning drugs by in vivo mutagenesis
Yunhwa Choi1, Changkyu Yoon2, Yeongjae Seok2, Jaehoon Yu1 (1Department of Chemistry &Education, Seoul National University, 2Department of Biological Science, Seoul National University)

P-121

Complexation of nucleic acids and peptides tethering a nuclear localization signal for intracellular
DNA delivery
Shunsuke Kataoka1, Takahito Imai1, Kenji Usui2, Kin-ya Tomizaki1 (1Department of Materials
Chemistry, Ryukoku University, 2Faculty of Frontiers of Innovative Research in Science and Technology(FIRST), Konan University)

P-122

Selective recovery of gold from mixtures of noble metal ions with aromatic ring-containing peptides
Takuya Okamoto, Takahito Imai, Kin-ya Tomizaki (Department of Materials Chemistry, Ryukoku
University)

P-123

Synthesis of titania nanostructures by silica etching of silica-peptide complex
Makoto Kasuga, Takahitio Imai, Kin-ya Tomizaki (Department of Materials Chemistry, Ryukoku
University)

P-124

Cell adhesion onto hydroxyapatite surface modified with collagen model peptides with a phosphategroup and cell recognition sequences.
Takumi Yamamoto, Takahito Imai, Kin-ya Tomizaki (Department of Materials Chemistry, Ryukoku
University)

P-125

Synthesis of fatty acid containing peptides and their use for gold nanocrystal synthesis as templates
Naoyuki Tsukamoto, Takahito Imai, Kin-ya Tomizaki (Department of Materials Chemistry, Ryukoku
University)

P-126

Synthesis of noble metal nanoparticals by peptides containing various aromatic side chains under lightirradiation conditions(19)

Takahiro Uchiyama, Takahito Imai, Kin-ya Tomizaki (Department of Materials Chemistry, Ruyukoku
University)
P-127

Design and synthesis of novel membrane lytic peptides for drug release tool from liposomal vehicle
Ayumi Kashiwada, Masaki Mizuno, Nami Aoyagi (Graduate School of Industrial Technology, Nihon
University)

P-128

Investigation of chain length of thermosensitive polyproline
Makoto Kitamura1, Mitsuhiro Yuge2, Sachiro Kakinoki3, Yoshiaki Hirano3, Masahito Oka4 (1National
Insititute of Technology, Nara College, 2Mitsuboshi Belting LTD., 3Department of Chemistry andMaterials Engineering, Faculty of Chemistry, Materials and Bioengineering, Kansai University,
4

P-129

Professor Emeritus, Osaka Prefecture University)

Fabrication of titanium-cell interface by peptide nanofibers with sequences for titanium binding andcell recognition
Koji Kawamoto1, Masayuki Yamasaki2, Takahito Imai1, Kin-ya Tomizaki1 (1Department of Materials
Chemistry, Ryukoku University, 2Department of Food Sciences and Human Nutrition, Ryukoku
University)

P-130

Preparation and dielectric properties of peptide nanotube organization controlling macro-dipole byusing bis-cyclic β peptide
Kazushi Takagaki, Shunsaku Kimura (Graduate School of Engineering, Kyoto University)

P-131

Regular alignment of chromophores at side chains along peptide nanotube self-assembling cyclic αand β-peptide
Yuki Tabata, Shunsaku Kimura (Department of Material Chemistry, Graduate School of Engineering,
Kyoto University)

P-132

Multifunctional mesoporous silica nanoparticles for boron neutron capture therapy
Vincent Jallet1, Guillaume Varès1, Cédric Rentier2, Yoshio Hayashi2 (1Advanced Medical
Instrumentation Unit, Okinawa Institute of Science and Technology, 2Department of Medicinal
Chemistry, Tokyo University of Pharmacy and Life Sciences)

P-133

Tunable formation of Lipid-peptide nanodiscs toward a novel liposome engineering
Hirotaka Hori1, Daizaburou Hiyama1, Kazunari Matsumura2 (1Graduate School of Engineering, Shibaura
Institute of Technology, 2Faculty of Engineering, Shibaura Institute of Technology)

P-134

Creation of photoresponsive artificial viral capsid bearing azobenzene
Seiya Fujita, Kazunori Matsuura (Department of Chemistry and Biotechnology, Graduate School ofEngineering, Tottori University)

P-135

Sign tuning of circularly polarized luminescence (CPL) in bipyrenyl peptides
Yuki Mimura1, Sayaka Kitamura1, Motohiro Shizuma2, Mizuki Kitamatsu1, Michiya Fujiki3, Yoshitane
Imai1 (1Department of Applied Chemistry, Faculty of Science and Engineering, Kindai University,2

Department of Biochemistry, Osaka Research Institute of Industrial Science and Technology, 3Graduate

School of Materials Science, Nara Institute of School and Technology)
P-136

A novel covalently-labeling method of IgG by using protein A-mimic peptide
Arisa Himeno, Yosuke Nakashima, Ryo Yatomaru, Shun Hashimoto, Md. Kamrul Hasan Khan,
Daiichiro Kato, Yuji Ito (Department of Chemistry and Bioscience, Graduate School of Science andEngineering, Kagoshima University)

P-137

Switch of DNA structure formation using PNA peptides with a protease substrate sequence(20)

Shungo Sakashita, Arisa Okada, Masayuki Shimooka, Yoshio Hamada, Kenji Usui (Faculty of Frontiersof Innovative Research in Science and Technology (FIRST), Konan University)
P-138

Design of β-hairpin peptides incorporating RGDS sequence
Ryosuke Yokokawa1, Ayaki Jo1, Sachiro Kakinoki1,2, Yoshiaki Hirano1,2 (1Faculty of Chemistry,
Materials and Bioengineering, Kansai University, 2Organization for Research and Development of
Innovative Science and Technology (ORDIST), Kansai University)

P-139

Producing nanomaterials by digestion of amyloid beta peptide using proteaseShin-ichiro Yokota1, Yasumasa Mashimo2, Eita Tatsumi1, Taishi Yamagihara1, Yoshio Hamada1, Rui
Kawatahara3, Youji Harada3, Masayosu Mie2, Eiry Kobatake2, Kenji Usui1 (1Faculty of Frontiers ofInnovative Research in Science and Technology (FIRST), Konan University, 2Department of Life
Science and Technology, School of Life Science and Technology, Tokyo Institute of Technology, 3Clean
Chemical Co., Ltd)

P-140

Functionalization of biomedical polymers using the poly(propylene oxide)-binding peptides as amolecular tool
Toshiki Sawada, Misaki Takizawa, Hiroki Fukuta, Takeshi Serizawa (Department of Chemical Scienceand Engineering, Tokyo Institute of Technology)

P-141

Antimicrobial and cell-membrane-penetrating activities of a histone H2B-derived fragment peptide
Nanako Yamanaka, Shawichi Iwamuro (Department of Biology, Faculty of Science, Toho University)

P-142

Homodimer function of human nuclear receptor ERRα evidenced using α-helix peptides in the dimer
interface
Xiaohui Liu1, Hiroyuki Nakagawa2, Makiko Sugiyama1, Ayami Matsushima1, Miki Shimohigashi2,
Yasuyuki Shimohigashi3 (1Department of Chemistry, Faculty and Graduate School of Science, Kyushu
University, 2Department of Earth System of Science, Faculty of Science, Fukuoka University, 3Risk
Science Project Laboratory, Kyushu University)

P-143

Peptide nucleic acid possessing PreQ1 as a cationic analogue of guanine
Toru Sugiyama1, Misaki Kohara1, Keiko Kuwata2, Yasutada Imamura3, Yosuke Demizu4, Masaaki
Kurihara5, Atsushi Kittaka1 (1Faculty of Pharmaceutical Sciences, Teikyo University, 2Institute ofTransformative Bio-Molecules (WPI-ITbM), Nagoya University, 3Faculty of Engineering, Kogakuin
University, 4Division of Organic Chemistry, National Institute of Health Sciences, Ministry of Healthand Welfare, 5School of Pharmacy, International University of Health and Welfare)P-144

A screen for Rab family proteins modulating secretion of INS-35, one of the C. elegans insulin-like
peptidesMasumi Ohnishi, Takashi Iwasaki, Tsuyoshi Kawano (Department of Life and Bioresource Sciences,
Graduate School of Agriculture, Tottori University)

P-145

Preparation of pigment-peptide complexes that partially lack bacteriochlorophyll a pigments from
LH2 proteins of purple photosynthetic bacteria
Yoshitaka Saga1,2, Yoshitaka Fukuda1 (1Faculty of Science and Engineering, Kindai University,
2

P-146

PRESTO, JST)

Mutual co-work between human nuclear receptor ERα and ERRγ requires their homodimerization
Xiaohui Liu1, Miki Shimohigashi2, Makiko Sugiyama3, Ayami Matsushima1, Yasuyuki Shimohigashi4(1Department of Chemistry, Faculty of Science, Kyushu University, 2Department of Earth System of(21)

Science, Faculty of Science, Fukuoka University, 3Department of Chemistry, Graduate School of Science,
Kyushu University, 4Risk Science Project Laboratory, Kyushu University)
P-147

Peptide selection against reactive small maolcular probes for protein imaging and opto-genetics byusing the diverse screening system
Mizuki Yamamoto1, Hiroki Suzuki1, Tomohiro Iwabuchi1, Takashi Kawakami1,2 (1Department of
Biotechnology, Faculty of Life and Environmental Sciences, University of Yamanashi, 2JST, PRESTO)

P-148

Effects of skipjack tuna-derived elastin peptide on ligament healing
Eri Shiratsuchi1, Masaki Hirukawa2, Masahiro Hasegawa3, Keiichi Miyamoto2, Michio Yamada1(1Research & Development division, Hayashikane Sangyo Co., Ltd., 2Department of Chemistry for
Materials, Faculty of Engineering, Mie University, 3Graduate School of Medicine, Mie University)

P-149

NPR-15, one of the C. elegnas neuropeptide receptors, regulates larval development
Kenjirou Matsushita, Tomohiro Bito, Takashi Iwasaki, Tsuyoshi Kawano (Graduate School of
Sustainability Science, Tottori University)

P-150

Synthesis of sugar conjugated palladium or platinum complexes and their inhibitory abilities on theinteraction of phosphorylated CUB domain-containing protein-1 with protein kinase c δ
Akihiro Nomoto1, Nozomi Sakamoto1, Ryuuichi Sakai2, Hiromi Kataoka3, Shigenobu Yano4, Akiya
Ogawa1 (1Graduate School of Engineering, Osaka Prefecture University, 2Division of Biochemistry,
Kitasato University School of Medicine, 3Graduate School of Medical Sciences, Nagoya City University,
4

P-151

KYOUSEI Science Center, Nara Women’s University)

Structural analyses of a linker region of the amyloid precursor protein
Mizuho Imamura1, Shingo Kanemura2, Masaki Okumura2, Shigeru Shimamoto1, Yuji Hidaka1(1Graduate School of Science and Engineering Research, Kindai University, 2Frontier Research Institutefor Interdisciplinary Sciences, Tohoku University)

P-152

Regulation of disulfide-coupled folding of a de novo designed protein
Saya Nishihara, Kosuke Toyama, Kenta Mori , Shigeru Shimamoto, Yuji Hidaka (Graduate School of
Science and Engineering Research, Kindai University)

P-153

Molecular evolution of L-PGDS: substrate recognittion mechanism of medaka L-PGDS
Kimi Torii1, Takahiro Maruno2, Yuji Kobayashi2, Yuji Hidaka1, Shigeru Shimamoto1 (1Graduate Schoolof Science and Engineering Research, Kindai University, 2Graduate School of Engineering, Osaka
University)

P-154

Development of a solid-phase assisted disulfide ligation for the synthesis of peptide-drug conjugates
Kyohei Muguruma, Takuya Shirasaka, Daichi Akiyama, Akihiro Taguchi, Kentaro Takayama, Atsuhiko
Taniguchi, Yoshio Hayashi (Department of Medicinal Chemistry, Tokyo University of Pharmacy andLife Sciences)

P-155

Development of high resolution separation capillary column for peptides and proteins
Hiroshi Kobayashi, Mayu Sukegawa, Hiroo Wada (Shinwa Chemical Industries, Ltd.)

P-156

Assay development for the determination of residual solvents in peptide drugs by ion chromatography
Miki Ohno, Ryosuke Yoshinaga, Hiromasa Sugiura, Yoshitaka Taniguchi (CMC Analysis Laboratory,
Toray Research Center, Inc.)

P-157

Site-selective dimerization of chymotrypsin using diphenyl phosphonate derivatives
Takahiro Hatakeyama1, Masato Koga1, Takuya Kumakura1, Takuma Hayakawa1, Hirofumi Kuroda2,
Yoshikazu Horino3, Hiroshi Oyama4, Jun-ichi Sagara1, Shin Ono1 (1Genome Biotechnology Laboratory,(22)

Kanazawa Institute of Technology, 2Department of General Education, Ishikawa National College ofTechnology, 3Graduate School of Science and Engineering, University of Toyama, 4Faculty of Scienceand Engineering, Setsunan University)
P-158

Disulfide-coupled folding of pro-uroguanylin on molecular evolution
Kenta Mori, Kosuke Toyama, Saya Nishihara, Shigeru Shimamoto, Yuji Hidaka (Graduate School of
Science and Engineering Research, Kindai University)

P-159

Proteomic and transcriptomic analyses of left ventricles in human dilated cardiomyopathy for
identification of novel diagnostic biomarkers
Mitsuhiro Nishigori1, Sayaka Muto1, Osamu Seguchi2, Norihide Fukushima2, Yoshihiko Ikeda3, Hatsue
Ishibashi-Ueda3, Naoto Minamino1 (1Omics Research Center, National Cerebral and CardiovascularCenter,
3

P-160

2

Department of Transplantation, National Cerebral and Cardiovascular Center Hospital,

Department of Pathology, National Cerebral and Cardiovascular Center Hospital)

Construction of modified skin sensitization assay systems using peptidyl microbeads
Kenji Usui1, Hiroshi Miyazaki 2, Yuuki Minamino 1, Hideaki Mekata3, Masayuki Takaishi 3, Hidefumi
Ikeda3, Kunihiko Yamashita, Yoshio Hamada (1Faculty of Frontiers of Innovative Research in Scienceand Technology (FIRST), Konan University, 2Daicel Corp., 3Mandom Corp.)

P-161

Novel dual-pore bead and the ultrahigh-throughput for peptide purification
Riichi Miyamoto1,2, Daming Gao2, Naohiro Tomari3, Yoshihiro Yamamoto3, Takashi Ohtani4, Hong-zhi
Bai1, Kazuki Nakanishi2 (1SnG Inc., 2Graduate School of Science, Kyoto University, 3Kyoto Municipal
Institute of Industrial Technology and Culture, 4Hamari Chemicals, Ltd.)(23)