Science First | Clinical study

Excellent marginal bone response
and healthy soft tissue for theAll-on-4® treatment concept withXeal™ and TiUltra™ surfaces
1-year results from a prospective clinical trial: Pilot study

Low marginal bone remodeling and very good soft tissue health with
NobelParallel CC TiUltra implants and Multi-unit Abutments Xeal,placed according to the All-on-4® treatment concept.
Ferro A, De Araújo Nobre M. All-on-4 concept using TiUltra surface implants and Multi-unit Xeal abutments: Pilot study report. Clin Oral
Implant Research 2021; 32(S22):59.

Study design

Prospective, single-center
16 patients‒ All-on-4® treatment concept‒ Maxilla (11) and mandible (5)Implant placement & Immediate Function‒ 64 NobelParallel CC TiUltra implants‒ 64 Multi-unit Abutments Xeal
‒ 16 fixed full-arch prostheses

The results‒ 100% cumulative implant survival
and prosthetic success.

‒ Low marginal bone remodeling with a meanof -0.46 mm from implant insertion to 1 year.
2.50

2.00

1.50

Final prosthesis delivery‒ 16 fixed full-arch final prostheses

1.00

0.50

1-year follow-up‒ 16 patients evaluated0.00
Marginal Bone Loss at 1 year

Clinical relevance‒ Very high implant and prosthetic survivalwith the All-on-4® treatment concept using
TiUltra implants and Xeal abutments.
‒ Excellent marginal bone response combinedwith good and stable soft tissue healthcan be achieved with TiUltra implants
and Xeal abutments for Immediate
Function full-arch restorations.

‒ Healthy and stable soft tissue response,with the low median sulcus bleeding index
of 1 (isolated bleeding spots visible whena periodontal probe is passed along thegingival margin) and mild plaque accumulation at the 1-year follow-up.
‒ No biological complications.

Sample clinical case from the study
Before surgery

At surgery

After surgery

1-year follow-up

acegbdfh

A 53-year-old female with failing dentition and severe bone atrophy in the maxilla (a,b) was treatedaccording to the All-on-4® treatment concept with four NobelParallel CC TiUltra implants andMulti-unit Abutments Xeal (c-e). A temporary prosthesis, Malo Clinic all-acrylic bridge, was placed on
the day of surgery (f) while the final prosthesis, Malo Clinic acrylic bridge on NobelProcera implant bar,
was placed 3 months later. At 1 year, the patient shows excellent soft tissue health around the final
restoration (g,h).
Images courtesy of Dr Ana Ferro. Video of the case available from the QR code below.

Xeal and TiUltra are well-documented,
clinically proven surfaces
In published studies as of February 2022

235 patients
377 TiUltra implants
160 Xeal abutments

Xeal and TiUltra
surfaces show
low marginal loss
and healthy soft
tissue responsewith the All-on-4®
treatment conceptMore to explore
Failing dentition andsevere bone atrophyin the maxilla
Clinical case video

Study presentation video
Dr. Ana Ferronobelbiocare.com/en-us/surfaces

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