2020/11/11
Publication List
1983
1.

Mukaiyama, T.; Ichikawa, J.; Asami, M. “Facile Method for the Acylation of Alcohols
and Amides by the Use of 1,1-Dimethylstannocene and Acyl Chlorides”, Chem. Lett. 1983,
12, 293–296.

2.

Mukaiyama, T.; Ichikawa, J.; Asami, M. “A Facile Synthesis of Carboxylic Esters andCarboxamides by the Use of 1,1'-Dimethylstannocene as a Condensing Reagent”, Chem.
Lett. 1983, 12, 683–686.

3.

Mukaiyama, T.; Ichikawa, J.; Toba, M.; Asami, M. “A Novel Method for the One-step
Synthesis of N-Alkyl Imides by the Use of 1,1'-Dimethyl-stannocene”, Chem. Lett. 1983,
12, 879–880.

1984
4.

Ichikawa, J.; Asami, M.; Mukaiyama, T. “An Asymmetric Synthesis of Glycerol
Derivatives by the Enantioselective Acylation of Prochiral Glycerol”, Chem. Lett. 1984,
13, 949–952.

1985
5.

Ichikawa J.; Mukaiyama, T. “A Facile Synthesis of α,β-Dihydroxyketones via Tin(IV)Enediolates by Utilizing the Reducing Power of Bis(2-pyridinethiolato)tin(II) ”, Chem.
Lett. 1985, 14, 1009–1012.

6.

Mukaiyama, T.; Ichikawa, J.; Toba, M.; Hayashi, M. “A Regio- and Stereoselective
Synthesis of Aldolized γ-Diketones via Tin(IV) Bisenolates by the Use ofBis(2-pyridinethiolato)tin(II) ”, Chem. Lett. 1985, 14, 1539–1542.

1986
7.

Mukaiyama, T.; Hayashi, M.; Ichikawa, J. “A Stereocontrolled Synthesis of
2,3,5-Trisubstituted Tetrahydrofurans from Aldolized γ-Diketones via Cyclization–
reduction Process”, Chem. Lett. 1986, 15, 1157–1160.

1987
8.

Ichikawa, J.; Sugimoto, K.; Sonoda, T.; Kobayashi, H. “A Facile Method for the FluorineSubstitution of Phenylthio Group via Sulfonium Salts Using Cesium Fluoride”, Chem. Lett.
1987, 16, 1985–1988.
1988
9.

Ichikawa, J.; Sonoda, T.; Kobayashi, H. “Radical Transport Reaction. Concurrent Transfer
of Electron and Proton”, Bull. Chem. Soc. Jpn. 1988, 61, 2923–2926.

1989
10. Ichikawa, J.; Sonoda, T.; Kobayashi, H. “A Novel Synthesis of 1,1-Difluoroolefins from
1,1,1-Trifluoroethyl p-Toluenesulfonate via Boron Ate-Complex”, Tetrahedron Lett. 1989,
30, 1641–1644.
11. Ichikawa, J.; Sonoda, T.; Kobayashi, H. “A Novel Synthesis of Difluoromethyl Ketones
from

2,2,2-Trifluoroethylp-Toluenesulfonate

via

2,2-Difluoroalkenylboranes”,

Tetrahedron Lett. 1989, 30, 5437–5438.
12. Ichikawa, J.; Sonoda, T.; Kobayashi, H. “Reactions of 2,2-Difluoroalkenylboranes with
Halogens in the Presence of Base. Novel Syntheses of Symmetrically Disubstituted
1,1-Difluoro-1-alkenes and 1,1-Difluoro-2-iodo-1-alkenes”, Tetrahedron Lett. 1989, 30,
6379–6382.

1991
13. Ichikawa, J.; Moriya, T.; Sonoda, T.; Kobayashi, H. “A Novel Synthesis of Disubstituted
1,1-Difluoro-1-alkenes

by

Using

2,2,2-Trifluoroethylp-Toluenesulfonateasa

Difluorovinylidene Unit”, Chem. Lett. 1991, 20, 961–964.

1992
14. Ichikawa, J.; Hamada, S.; Sonoda, T.; Kobayashi, H. “A One-Pot Synthesis of
2,2-Difluorovinyl Carbonyl Compounds from 2,2,2-Trifluoroethyl p-Toluenesulfonate via
2,2-Difluorovinylboranes”, Tetrahedron Lett. 1992, 33, 337–340.
15. Okada, Y.; Minami, T.; Yamamoto, T.; Ichikawa, J. “A Novel Type of Chiral Diphosphine
Ligand, trans-2,3-Bis(diphenylphosphino)-1-methyl-1-cyclopropanecarboxylic Acid andAsymmetric Allylic Alkylation by the Use of Its Palladium Complex”, Chem. Lett. 1992,
21, 547–550.

16. Ichikawa, J.; Minami, T.; Sonoda, T.; Kobayashi, H. “A Facile Synthesis of Disubstituted
1,1-Difluoro-1-alkenes via

DoubleTransmetalationof 2,2-Difluorovinylboranes”,

Tetrahedron Lett. 1992, 33, 3779–3782.
17. Fujiki, K.; Kashiwagi, M.; Miyamoto, H.; Sonoda, A.; Ichikawa, J.; Kobayashi, H.;
Sonoda, T. “Syntheses and Lipophilicities of Tetraarylborate Ions Substituted with Many
Trifluoromethyl Groups”, J. Fluorine Chem. 1992, 57, 307–321.
18. Ichikawa, J.; Ikeura, C.; Minami, T. “A New Synthesis of 1,1-Difluoro-1,3-dienes via the
Coupling Reaction of 2,2-Difluoro-vinylboranes”, Synlett 1992, 1992, 739–740.
19. Ichikawa, J.; Yonemaru, S.; Minami, T. “A Novel Synthesis of 2,2-Difluorovinyl- and2-Fluorovinylphosphorus Compounds from 2,2,2-Trifluoroethyl p-Toluenesulfonate”,
Synlett 1992, 1992, 833–834.

1993
20. Ichikawa, J.; Yokota, N.; Kobayashi, M.; Minami, T. “The Reaction of Fluorovinyl
Ketones with Carbon Nucleophiles:

A New General Route to α,β-Unsaturated Ketones”,

Synlett 1993, 1993, 186–188.
21. Ichikawa, J.; Ikeura, C.; Minami, T. “A One-Pot Synthesis of Conjugated Fluoroenynes
via 2,2-Difluorovinylcopper Intermediates”, J. Fluorine Chem. 1993, 63, 281–285.
22. Minami, T.; Kamitamari, M.; Utsunomiya, T.; Tanaka, T.; Ichikawa, J. “Synthesis ofAnnulated γ-Lactams via Intramolecular 1,3-Dipolar Cycloadditions of Functionalized
N-Allyl α-Diazo Amides”, Bull. Chem. Soc. Jpn. 1993, 66, 1496–1500.
23. Minami, T.; Isonaka, T.; Okada, Y.; Ichikawa, J. “Copper(I) Salt-Mediated Arylation of
Phosphinyl-Stabilized Carbanions and Synthetic Application to Heterocyclic Compounds”,
J. Org. Chem. 1993, 58, 7009–7015.
24. Okada, Y.; Minami, T.; Ichikawa, J. “A Novel Type of Chiral Diphosphine Ligand,trans-2,3-Bis(diphenylphosphino)-1-methyl-1-cyclopropanecarboxylic

Acid

and

Asymmetric Allylic Alkylation by the Use of Its Palladium Complex”, Phosphorus, Sulfur,
and Silicon 1993, 77, 153.

1994
25. Ichikawa, J.; Kobayashi, M.; Yokota, N.; Noda, Y.; Minami, T. “Reaction of
2,2-Difluorovinyl Ketones with Heteroatom Nucleophiles:

A General One-Pot Synthesisof α-Oxoketene Acetals1”, Tetrahedron 1994, 50, 11637–11646.

26. Minami, T.; Utsunomiya, T.; Nakamura, S.; Okubo, M.; Kitamura, N.; Okada, Y.;
Ichikawa, J. “Intramolecular Ene Reaction of Vinylphosphonates. Synthetic Application to
Bicyclic Compounds and Cadalane and Valerenic Acid Terpenoids”, J. Org. Chem. 1994,
59, 6717–6727.

1995
27. Ichikawa, J.; Miyazaki, S.; Fujiwara, M.; Minami, T. “Fluorine-Directed Nazarov
Cyclizations:

A Controlled Synthesis of Cross-Conjugated 2-Cyclopenten-1-ones”, J.

Org. Chem. 1995, 60, 2320–2321.
28. Okada, Y.; Minami, T.; Miyamoto, M.; Otaguro, T.; Sawasaki, S.; Ichikawa, J.
“Construction of α-Phosphonolactams via Rhodium (II)-Catalyzed Intramolecular C–H
Insertion Reactions”, Heteroatom Chem. 1995, 6, 195–210.

1996
29. Ichikawa, J.; Yokota, N.; Kobayashi, M.; Amano, K.; Minami, T. “The Reaction of
2,2-Difluorovinyl Ketones with Amines:

A Facile Method for Preparation of

α-Oxoketenimines and Acetoacetylation of Amines”, Synlett 1996, 1996, 243–245.
30. Ichikawa, J.; Kobayashi, M.; Noda, Y.; Yokota, N.; Amano, K.; Minami, T.
“Regiocontrolled Syntheses of 3- or 5-Fluorinated Pyrazoles from 2,2-Difluorovinyl
Ketones”, J. Org. Chem. 1996, 61, 2763–2769.
31. Ichikawa,

J.;

Fujiwara,

M.;

Nawata,H.;

Okauchi,T.;

Minami,T.

“Novel2,2-Difluorovinylzirconocene: A Facile Synthesis of Monosubstituted gem-Difluoroolefins
via Its Cross-Coupling Reaction”, Tetrahedron Lett. 1996, 37, 8799–8802.
32. Minami, T.; Okauchi, T.; Matsuki, H.; Nakamura, M.; Ichikawa, J.; Ishida, M. “Synthesis
and Synthetic Application of Phosphonoketene Dithioacetals. New Synthesis of
Dithioallenes and (α-Dithiocarboxyvinyl) phosphonates”, J. Org. Chem. 1996, 61, 8132–
8140.

1997
33. Ichikawa, J.; Wada, Y.; Okauchi, T.; Minami, T. “5-endo-Trigonal Cyclization ofo-Substituted gem-Difluorostyrenes: Syntheses of 2-Fluorinated Indoles, Benzo[b]furans,
and Benzo[b]thiophenes”, Chem. Commun. 1997, 1537–1538.
34. Okauchi,

T.;Fukamachi,

T.;

Nakamura,F.;

Ichikawa,

J.;

Minami,T.

“2-Phosphono-1,1,4,4-tetrathio-1,3-butadienes.

Synthesis and Synthetic Application toHighly Functionalized Dienes and Heterocycles”, Bull. Soc. Chim. Belg. 1997, 106, 525–
532.
35. Okauchi, T.; Kakiuchi, T.; Kitamura, N.; Utsunomiya, T.; Ichikawa, J.; Minami, T. “Lewis
Acid-Catalyzed Intramolecular [2+2] Cycloaddition of α-Ester-Substituted Conjugated
Dienyl- and Trienylphosphonates.

New Synthesis of Functionalized Cyclic Terpenoids”,

J. Org. Chem. 1997, 62, 8419–8424.

1998
36. Ichikawa, J.; Fujiwara, M.; Okauchi, T.; Minami, T. “Fluorine-Directed Nazarov
Cyclizations 2: Regioselective Synthesis of 5-Trifluoromethyl-2-cyclopentenones”, Synlett
1998, 1998, 927–929.
37. Kouno, R.; Okauchi, T.; Nakamura, M.; Ichikawa, J.; Minami, T. “Synthesis and Synthetic
Utilization of α-Functionalized Vinylphosphonates Bearing β-Oxy or β-Thio Substituents”,
J. Org. Chem. 1998, 63, 6239–6246.

1999
38. Ichikawa, J.; Jyono, H.; Yonemaru, S.; Okauchi, T.; Minami, T. “A Facile Synthesis of
1-H-2,2-Difluorovinylphosphorus

Compoundsfrom

2,2,2-Trifluoroethyl

Trifluoromethanesulfonate and Substitutions of Their Vinylic Fluorines”, J. Fluorine
Chem. 1999, 97, 109–114.
39. Okauchi, T.; Yano, T.; Fukamachi, T.; Ichikawa, J.; Minami, T. “α–Phosphonovinyl
Nonaflate: Their Synthesis and Cross-Coupling Reactions”, Tetrahedron Lett. 1999, 40,
5337–5340.
40. Fujiwara, M.; Ichikawa, J.; Okauchi, T.; Minami, T. “Vinylic C–F Bond Activation with
Low-Valent

Zirconocene:theGeneration

andCross-Coupling

Reactionsof

1-Fluorovinylzirconocene”, Tetrahedron Lett. 1999, 40, 7261–7265.
41. Hori, K.; Fukuda, S.; Kawano, Y.; Ichikawa, J. “Ab Initio Molecular Orbital Study of
Substitution on the Vinylic Carbon in F2C=C(OMs)BMe3– under SN1-like Mechanism”,
JCPE J. 1999, 11, 23–28.
42. Hori, K.; Fukuda, S.; Ichikawa, J. “Ab Initio Molecular Orbital Study on Three Feasible
Mechanisms for Substitution on the Vinylic Carbon in F2C=C(OMs)BMe3–”, Tetrahedron
1999, 55, 14915–14924.

43. Minami, T.; Kouno, R.; Okauchi, T.; Nakamura, M.; Ichikawa, J. “Synthetic Utilization of
α-Phosphonovinyl Anions”, Phosphorus, Sulfur and Silicon 1999, 144–146, 689–692.
2000
44. Okauchi, T.; Nagamori, H.; Kouno, R.; Ichikawa, J.; Minami, T. “Synthesis of
5-Diphenylphosphinoyl-2,3-dihydropyran-4-ones”, Heterocycles 2000, 52, 1393–1398.
45. Fujiki, K.; Ichikawa, J.; Kobayashi, H.; Sonoda, A.; Sonoda, T. “Syntheses of Lipophilic
Tetraarylborate Ions Substituted with Many Perfluoroalkyl Groups and Their Stability
under Acid Conditions”, J. Fluorine Chem. 2000, 102, 293–300.
46. Ichikawa, J. “gem-Difluoroolefin Synthesis: General Methods via Thermostable
Difluorovinylmetals Starting from 2,2,2-Trifluoroethanol Derivatives”, J. Fluorine Chem.
2000, 105, 257–263.
47. Ichikawa, J.; Fujiwara, M.; Wada, Y.; Okauchi, T.; Minami, T. “The Nucleophilic
5-endo-trig Cyclization of gem-Difluoroolefins with Homoallylic Functional Groups:
Syntheses of Ring-Fluorinated Dihydroheteroaromatics”, Chem. Commun. 2000, 1887–
1888.
48. Ichikawa, J. “Ring Constructions by the Use of Fluorine Substituent as Activator andController”, Pure Appl. Chem. 2000, 72, 1685–1689.

2001
49. Wada, Y.; Ichikawa, J.; Katsume, T.; Nohiro, T.; Okauchi, T.; Minami, T. “Intramolecular
Cyclizationsofo-Substituted

β,β-Difluorostyrenes:

Synthesisof

3-FluorinatedIsochromenes and Isothiochromenes”, Bull. Chem. Soc. Jpn. 2001, 74, 971–977.
50. Ichikawa, J.; Fujiwara, M.; Miyazaki, S.; Ikemoto, M.; Okauchi, T.; Minami, T.
“Regioselective Nucleophilic Additions to Cross-Conjugated Dienone System Bearing
β-Fluorine: A Versatile Approach to Highly Substituted 2-Cyclopentenones”, Org. Lett.
2001, 3, 2345–2348.

2002
51. Ichikawa, J.; Sakoda, K.; Wada, Y. “The 5-endo-trig Cyclization of gem-Difluoroolefinswith sp3 Carbon Nucleophiles: Synthesis of 1-Fluorocyclopentenes”, Chem. Lett. 2002, 31,
282–283.
52. Ichikawa, J.; Wada, Y.; Fujiwara, M.; Sakoda, K. “The Nucleophilic 5-endo-trig

Cyclization of 1,1-Difluoro-1-alkenes: Ring-Fluorinated Hetero- and Carbocycle Synthesis
and Remarkable Effect of the Vinylic Fluorines on the Disfavored Process”, Synthesis(Feature Article) 2002, 2002, 1917–1936.
53. Ichikawa, J.; Saitoh, T.; Tada, T.; Mukaiyama, T. “A Convenient Method for Carbon
Extension of Acetals and Aldehydes by the Use of Ketenedithioacetal and Nucleophiles”,
Chem. Lett. 2002, 31, 996–997.

2003
54. Ichikawa, J.; Ishibashi, Y.; Fukui, H. “A Novel Synthesis of Functionalized
1,1-Difluoro-1-alkenes via Isolable 2,2-Difluorovinylsilanes”, Tetrahedron Lett. 2003, 44,
707–710.
55. Ichikawa, J.; Wada, Y.; Miyazaki, H.; Mori, T.; Kuroki, H. “Ring-FluorinatedIsoquinoline and Quinoline Synthesis: Intramolecular Cyclization of o-Cyano- ando-Isocyano-β,β-difluorostyrenes”, Org. Lett. 2003, 5, 1455–1458.
56. Ichikawa, J.; Fukui, H.; Ishibashi, Y. “1-Trifluoromethylvinylsilane as a CF2=C––CH2+
Synthon:SynthesisofFunctionalized

1,1-Difluoro-1-alkenes

via

Isolable

2,2-Difluorovinylsilanes”, J. Org. Chem. 2003, 68, 7800–7805.
57. Wada, Y.; Mori, T.; Ichikawa, J. “A Facile Synthesis of 2,4-Disubstituted
3-Fluoroquinolines

via

Intramolecular

Cyclizationofo-Cyanomethylamino-β,β-difluorostyrenes”, Chem. Lett. 2003, 32, 1000–1001.

2004
58. Mori, T.; Ichikawa, J. “KCN-Catalyzed C–C Bond Formation between Imine andgem-Difluoroalkene Moieties: A Facile Synthesis of 2,4-Disubstituted 3-Fluoroquinolines”,
Chem. Lett. 2004, 33, 590–591.
59. Ichikawa, J.; Miyazaki, H.; Sakoda, K.; Wada, Y. “Ring-Fluorinated Naphthalene andIndene Synthesis via 6- and 5-endo-trig Cyclizations of gem-Difluoroalkenes by Carbon
Nucleophiles”, J. Fluorine Chem. 2004, 125, 585–593.
60. Ichikawa, J.; Mori, T.; Miyazaki, H.; Wada, Y. “C–C Bond Formation between Isocyanideand β,β-Difluoroalkene Moieties via Electron Transfer: Fluorinated Quinoline andBiquinoline Syntheses”, Synlett 2004, 2004, 1219–1222.
61. Saitoh, T.; Jimbo, N.; Ichikawa, J. “A Novel Synthesis of syn and anti β-Hydroxy
Dithioacetals, Masked Cross-Aldols between Aldehydes”, Chem. Lett. 2004, 33, 1032–

1033.
62. Mori, T.; Ichikawa, J. “4-Difluoromethylated Quinoline Synthesis via Intramolecular SN2ʹReaction of α-Trifluoromethylstyrenes Bearing Imine Moieties”, Chem. Lett. 2004, 33,
1206–1207.
63. Ichikawa, J.; Mori, T.; Iwai, Y “A New Class of Substrates for the Nucleophilic
5-endo-trig Cyclization, 1-Trifluoromethylvinyl Compounds: Syntheses of Indoline andPyrrolidine Derivatives”, Chem. Lett. 2004, 33, 1354–1355.
64. Saitoh, T.; Yoshida, S.; Ichikawa, J. “1,8-Bis(diphenylmethylium)naphthalenediyl
Dication as an Organic Oxidant: Synthesis of Benzidines via Self-Coupling of
N,N-Dialkylanilines”, Org. Lett. 2004, 6, 4563–4565.

2005
65. Ichikawa, J.; Jyono, H.; Kudo, T.; Fujiwara M.; Yokota M. “Friedel–Crafts Cyclization of
1,1-Difluoroalk-1-enes:

SynthesisofBenzene-Fused

CyclicKetonesvia

α-Fluorocarbocations”, Synthesis 2005, 2005, 39–46.
66. Mori,

T.;

Iwai,

Y.;

Ichikawa,

J.

“Cyclizationofo-Functionalized

α-Trifluoromethylstyrenes: Synthesis of Isoquinoline Derivatives Bearing Fluorinated
One-Carbon Units”, Chem. Lett. 2005, 34, 778–779.
67. Saitoh, T.; Ichikawa, J. “Bis(triarylmethylium)-Mediated Diaryl Ether Synthesis:
Oxidative Arylation of Phenols with N,N-Dialkyl-4-phenylthioanilines”, J. Am. Chem. Soc.
2005, 127, 9696–9697.
68. Sakoda, K.; Mihara, J.; Ichikawa, J. “Heck-Type 5-endo-trig Cyclization Promoted by
Vinylic Fluorines: Synthesis of 5-Fluoro-3H-Pyrroles”, Chem. Commun. 2005, 4684–
4686.
(“Synthesis of Fluoropyrroles” Synfacts 2005, 3, 292.)

2006
69. Nadano, R.; Ichikawa, J. “1-(Trifluoromethyl) vinylation via Oxirane or Oxetane Ring
Opening:A

FacileSynthesis

of

4-

or

5-Hydroxy-Functionalized

2-Trifluoromethyl-1-alkenes”, Synthesis 2006, 2006, 128–132.
70. Ichikawa, J.; Sakoda, K.; Mihara, J.; Ito, N. “Heck-Type 5-endo-trig Cyclizations
Promoted by Vinylic Fluorines: Ring-Fluorinated Indene and 3H-Pyrrole Syntheses from
1,1-Difluoro-1-alkenes”, J. Fluorine Chem. 2006, 127, 489–504.

71. Ichikawa, J.; Sakoda, K.; Moriyama, H.; Wada, Y. “Syntheses of Ring-FluorinatedIsoquinolines

andQuinolines

via

Intramolecular

Substitution:

Cyclizationof

1,1-Difluoro-1-alkenes Bearing a Sulfonamide Moiety”, Synthesis 2006, 2006, 1590–
1598.
72. Ichikawa, J.; Kaneko, M.; Yokota, M.; Itonaga, M. Yokoyama, T. “Friedel–Crafts-Type
Cyclization of 2,2-Difluorovinyl Ketones via α-Fluorocarbocations and Its Application in
Domino Cyclizations”, Org. Lett. 2006, 8, 3167–3170.
73. Saitoh, T.; Yoshida, S.; Ichikawa, J. “Naphthalene-1,8-diylbis(diphenylmethylium) as an
Organic Two-Electron Oxidant: Benzidine Synthesis via Oxidative Self-Coupling of
N,N-Dialkylanilines”, J. Org. Chem. 2006, 71, 6414–6419.
74. Ichikawa, J.; Nadano, R.; Mori, T.; Wada, Y. “5-Endo-trig Cyclization of
1,1-Difluoro-1-alkenes:

Synthesisof

3-Butyl-2-fluoro-1-tosylindole(1H-Indole,

3-butyl-2-fluoro-1-[(4-methylphenyl)sulfonyl]-) ”, Org. Synth. 2006, 83, 111–120.
75. Ichikawa,J.;

Nadano,

R.;

Ito,

N.

“5-endoHeck-Type

Cyclizationof

2-(Trifluoromethyl)allyl Ketone Oximes: Synthesis of 4-Difluoromethylene-Substituted
1-Pyrrolines”, Chem. Commun. 2006, 4425–4427.
76. Nadano, R.; Iwai, Y.; Mori, T.; Ichikawa, J. “Divergent Chemical Synthesis of Prolines
Bearing Fluorinated One-Carbon Units at the 4-Position via Nucleophilic 5-Endo-Trig
Cyclizations”, J. Org. Chem. 2006, 71, 8748–8754.

2007
77. Ichikawa, J. “Construction of Fluorinated Heterocycles: Intramolecular Substitution and
Addition of Fluoro Alkenes”, Chim. Oggi 2007, 25(4), 54–57.
78. Nadano, R.; Ichikawa, J. “A Facile Synthesis of N-[2-(Trifluoromethyl) allyl]amides andTheir Transformation into Angularly Trifluoromethylated Bicyclic Cyclopentenones”,
Chem. Lett. 2007, 36, 22–23.
79. Mori,

T.;

Ichikawa,

J.

“Radical

6-endo-trig

Cyclizationof

β,β-Difluoro-o-isocyanostyrenes: A Facile Synthesis of 3-Fluoroquinolines and Their
Application to the Synthesis of 11-Alkylated Cryptolepines”, Synlett 2007, 2007, 1169–
1171.
80. Ichikawa, J.; Lapointe, G.; Iwai, Y. “Nucleophilic 5-endo-trig Cyclizations of
N-Homoallylic Sulfonamides: A Facile Method for the Construction of Pyrrolidine Rings”,
Chem. Commun. 2007, 2698–2700.

81. Yokota, M.; Fujita, D.; Ichikawa, J. “Activation of 1,1-Difluoro-1-alkenes with aTransition-Metal Complex: Palladium(II)-Catalyzed Friedel–Crafts-Type Cyclization of4,4-(Difluorohomoallyl)arenes”, Org. Lett. 2007, 9, 4639–4642.
82. Ichikawa, J.; Wada, Y.; Kuroki, H.; Mihara, J.; Nadano, R. “Intramolecular Cyclization of
β,β-Difluorostyrenes Bearing an Iminomethyl or a Diazenyl Group at the Ortho Position:
Synthesis of 3-Fluorinated Isoquinoline and Cinnoline Derivatives”, Org. Biomol. Chem.
2007, 5, 3956–3962.

2008
83. Ichikawa, J.; Iwai, Y.; Nadano, R.; Mori, T.; Ikeda, M. J. “A New Class of Substrates for
Nucleophilic

5-endo-trig

Cyclization,

2-Trifluoromethyl-1-alkenes:

SynthesisofFive-Membered Hetero- and Carbocycles That Bear Fluorinated One-Carbon Units”,
Chem. Asian J. 2008, 3, 393–406.
84. Miura, K.; Tomita, M.; Ichikawa, J.; Hosomi, A. “Indium(III) Acetate-Catalyzed
Intermolecular Radical Addition of Organic Iodides to Electron-Deficient Alkenes”, Org.
Lett. 2008, 10, 133–136.
85. Miura, K.; Horiike, M.; Inoue, G.; Ichikawa, J.; Hosomi, A. “Platinum(II)-Catalyzed
Annulation of 5-Methyl-5-hexen-1-ols with Aldehydes”, Chem. Lett. 2008, 37, 270–271.
86. Ichikawa, J.; Yokota, M.; Kudo, T.; Umezaki, S. “Efficient Helicene Synthesis: Friedel–
Crafts-Type Cyclization of 1,1-Difluoro-1-alkenes”, Angew. Chem. Int. Ed. 2008, 47,
4870–4873.
(“Domino Friedel–Crafts Cyclization for Helicene Synthesis”, Synfacts 2008, 9, 936.)

2009
87. Ichikawa, J.; Ikeda, M.; Hattori, M. “Synthesis of Isochromanes and Isothiochromanes
Bearing

Fluorinated

One-Carbon

Units

via

Intramolecular

Cyclizations

ofortho-Substituted α-(Trifluoromethyl)styrenes”, Heterocycles 2009, 77, 1285–1296.
88. Yokota, M.; Fuchibe, K.; Ueda, M.; Mayumi, Y.; Ichikawa, J. “Facile Synthesis of
1,1-Difluoroallenes via the Difluorovinylidenation of Aldehydes and Ketones”, Org. Lett.
2009, 11, 3994–3997.
89. Isobe, H.; Hitosugi, S.; Matsuno, T.; Iwamoto, T.; Ichikawa, J. “Concise Synthesis of
Halogenated Chrysenes ([4]Phenacenes) That Favor π-Stack Packing in Single Crystals”,
Org. Lett. 2009, 11, 4026–4028.

(“Synthesis of Chrysenes through an Unexpected Skeletal Rearrangement”, Synfacts 2009,11, 1211.)
90. Miura, K.; Inoue, G.; Sasagawa, H.; Kinoshita, H.; Ichikawa, J.; Hosomi, A.
“Platinum-Catalyzed Nucleophilic Addition of Vinylsilanes at the β-Position”, Org. Lett.
2009, 11, 5066–5069.
91. Miura, K.; Ebine, M.; Ootsuka, K.; Ichikawa, J.; Hosomi, A. “Efficient Alkenation of
Aldehydes

andKetonestoEstersα, β-Unsaturated

Using

α,α-Bis(dimethylsilyl)-substituted Esters”, Chem. Lett. 2009, 38, 832–833.
92. Miura, K.; Izumi, H.; Kinoshita, H.; Ichikawa, J.; Hosomi, A. “Platinum(II)-Catalyzed
Acetal–Ene Reaction: Easy Access to Homoallylic Ethers”, Chem. Lett. 2009, 38, 1204–
1205.

2010
93. Tanabe, H.; Kawai, T.; Saitoh, T.; Ichikawa, J. “Oxidative Arylation Mediated byNaphthalene-1,8-diylbis(diphenylmethylium): Synthetic Route to Triarylsulfonium Salts”,
Chem. Lett. 2010, 39, 56–57.
94. Tanabe, H.; Ichikawa, J. “Transition-Metal-Catalyzed Electrophilic Activation of
1,1-Difluoro-1-alkenes: Oxindole Synthesis via Intramolecular Amination”, Chem. Lett.
2010, 39, 248–249.
95. Miura, K.; Yamamoto, K.; Yamanobe, A.; Ito, K.; Kinoshita, H.; Ichikawa, J.; Hosomi, A.
“Indium(III)-catalyzed Coupling between Alkynes and Aldehydes to α,β-Unsaturated
Ketones”, Chem. Lett. 2010, 39, 766–767.
96. Nadano, R.; Fuchibe, K.; Ikeda, M.; Takahashi, H.; Ichikawa, J. “Rapid and Slow
Generationof

1-Trifluoromethylvinyllithium:SynthesesandApplicationsof

CF3-Containing Allylic Alcohols, Allylic Amines, and Vinyl Ketones”, Chem. Asian J.
2010, 5, 1875–1883.
97. Ichikawa, J. “Synthetic Methods for Heterocycles and Carbocycles Bearing Fluorinated
One-Carbon

Units(=CF2,

CHF2,

or

CF3):

Intramoelcular

Reactionof

2-Trifluoromethyl-1-alkenes”, J. Synth. Org. Chem., Jpn. 2010, 68, 1175–1184. [Invited].

2011
98. Oh, K.; Fuchibe, K.; Ichikawa, J. “A Facile Synthesis of 1,1-Difluoroallenes from
Commercially Available 1,1,1-Trifluoro-2-iodoethane”, Synthesis 2011, 2011, 881–886.

(“Greener 1,1-Difluoroallenes”, Synfacts 2011, 6, 609.)
99. Ichikawa,J.

“5-endo-trig

Cyclizationof

1,1-Difluoro-1-Alkenes:

Synthesis

3-Butyl-2-Fluoro-1-Tosylindoleof(1H-Indole,

3-Butyl-2-Fluoro-1-[(4-Methylphenyl)Sulfonyl]-) ”, Org. Synth. 2011, 88, 162–167.
100. Nakanishi, W.; Matsuno, T.; Ichikawa, J.; Isobe, H. “Illusory Molecular Expression of“Penrose Stairs” by an Aromatic Hydrocarbon”, Angew. Chem. Int. Ed. 2011, 50, 6048–
6051.
101. Fuchibe, K.; Jyono, H.; Fujiwara, M.; Kudo, T.; Yokota, M.; Ichikawa, J. “Domino
Friedel–Crafts-Type

Cyclizationsof

Difluoroalkenes

Promotedbytheα-Cation-Stabilizing Effect of Fluorine: An Efficient Method for Synthesizing Angular
PAHs”, Chem. Eur. J. 2011, 17, 12175–12185.
102. Fujita,

T.;

Ichitsuka,

T.;

Fuchibe,K.;

Ichikawa,

J.

“FacileSynthesisofβ,β-Difluorostyrenes via the Negishi Coupling of Thermally Stable 2,2-Difluorovinyl
Zinc–TMEDA Complex”, Chem. Lett. 2011, 40, 986–988.
103. Fuchibe, K.; Koseki, Y.; Sasagawa, H.; Ichikawa, J. “N-Heterocyclic Carbene-catalyzed
Difluorocarbene Generation and Its Application to Aryl Difluoromethyl Ether Synthesis”,
Chem. Lett. 2011, 40, 1189–1191.

2012
104. Fuchibe, K.; Koseki, Y.; Aono, T.; Sasagawa, H.; Ichikawa, J. “NHC-Catalyzed
Generation of Difluorocarbene and its Application to Difluoromethylation of Oxygen
Nucleophiles”, J. Fluorine Chem. 2012, 133, 52–60.
105. Oh, K.; Fuchibe, K.; Yokota, M.; Ichikawa, J. “Facile Synthesis of Substituted
1,1-Difluoroallenes via Carbonyl Difluorovinylidenation”, Synthesis 2012, 44, 857–861.
[Invited]
106. Kubota, T.; Ihara, M.; Katayama, S.; Nakai, H.; Ichikawa, J. “1,1-Difluoro-1-alkenes as
New Electrolyte Additives for Lithium Ion Batteries”, J. Power Sources 2012, 207, 141–149.
107. Fuchibe, K.; Ueda, M.; Yokota, M.; Ichikawa, J. “γ-Selective Addition to
1,1-Difluoroallenes:

Three-Component

Coupling

Leadingto2,2-Disubstituted

1,1-Difluoroalkenes”, Chem. Lett. 2012, 41, 1619–1621.
108. Fuchibe, K.; Takahashi, M.; Ichikawa, J. “Substitutions of Two Fluorine Atoms in a
Trifluoromethyl Group: Regioselective Synthesis of 3-Fluoropyrazoles”, Angew. Chem.

Int. Ed. 2012, 51, 12059–12062.
(“Synthesis of 3-Fluoropyrazoles from 2-Trifluoromethyl-1-alkenes”, Synfacts 2013, 9,
21.)

2013
109. Fujita, T.; Sakoda, K.; Ikeda, M.; Hattori, M.; Ichikawa, J. “Nucleophilic 5-endo-trig
Cyclization of 3,3-Difluoroallylic Ketone Enolates: Synthesis of 5-Fluorinated
2-Alkylidene-2,3-dihydrofurans”, Synlett 2013, 24, 57–60.
110. Suzuki, T.; Tamaoki, H.; Katoono, R; Fujiwara, K.; Ichikawa, J.; Fukushima, T. “Redox
switching of conjugation length using 9,9,10,10-tetraaryl-9,10-dihydrophenanthrene as an
ON/OFF unit: Preparation, X-ray structure, and redox properties of perfluorobiphenyl
derivative and its SNAr reactions to π-extended analogues”, Chem. Lett. 2013, 42, 703–
705.
111. Fuchibe, K.; Mayumi, Y.; Zhao, N.; Watanabe, S.; Yokota, M.; Ichikawa, J. “Domino
Synthesis of Fluorine-Substituted PAHs: 1,1-Difluoroallenes as Synthetic Platforms”,
Angew. Chem. Int. Ed. 2013, 52, 7825–7828.
(“Polycyclic Aromatic Hydrocarbons from 1,1-Difluoroallenes,"Synfacts 2013, 9, 1060.)
112. Fujita, T. Suzuki, N.; Ichitsuka, T.; Ichikawa, J. “Facile Synthesis of Unsymmetrical
1,1-Diaryl-2,2-difluoroethenes

via

Stepwise

Couplingof

1,1-Dibromo-2,2-difluoroethenes”, J. Fluorine. Chem. 2013, 155, 97–101.
113. Ichikawa, J.; Tanabe, H.; Yoshida, S.; Kawai, T.; Shinjo, M.; Fujita, T. “A New Organic
Two-Electron

Oxidant:

9,10-Diaryl-9,10-dihydroanthracene-9,10-bis(ylium)”,

Chem.

Asian J. 2013, 8, 2588–2591.
114. Jinzaki, T.; Arakawa, M.; Kinoshita, H.; Ichikawa, J.; Miura, K. “Nucleophilic Addition of
α-(Dimethylsilyl)nitriles to Aldehydes and Ketones”, Org. Lett. 2013, 15, 3750–3753.
2014
115. Fujita, T.; Sanada, S.; Chiba, Y.; Sugiyama, K.; Ichikawa, J. “Two-Step Synthesis ofDifluoromethyl-Substituted 2,3-Dihydrobenzoheteroles”, Org. Lett. 2014, 16, 1398–1401.
(“Allylation–Radical Cyclization to Difluoromethylated Dihydrobenzoheteroles,” Synfacts
2014, 10, 576.)116. Fujita, T.; Ikeda, M.; Hattori, M.; Sakoda, K.; Ichikawa, J. “Nucleophilic 5-endo-trig
Cyclization of 3,3-Difluoroallylic Metal Enolates and Enamides: Facile Synthesis of
Ring-Fluorinated Dihydroheteroles”, Synthesis 2014, 46, 1493–1505.
117. Ichitsuka, T.; Fujita, T.; Arita, T.; Ichikawa, J. “Double C–F Bond Activation via
Elimination:β-Fluorine

Nickel-Mediated[3+2]

Cycloadditionof

2-Trifluoromethyl-1-alkenes with Alkynes”, Angew. Chem. Int. Ed. 2014, 53, 7564–7568.
[Cover Picture] (Angew. Chem. Int. Ed. 2014, 53, 7371–7371.)
118. Fuchibe, K.; Mayumi, Y.; Yokota, M.; Aihara, H; Ichikawa, J. “Indium(III)-Catalyzed
Cationic

Cyclizationof

1,1-Difluoroallenes:

Regioselective

Synthesisof

1-Fluoronaphthalenes”, Bull. Chem. Soc. Jpn. 2014, 87, 942–949.
[BCSJ Award, Cover Picture]2015
119. Ichitsuka, T.; Takanohashi, T.; Fujita, T.; Ichikawa, J. “A Versatile Difluorovinylation
Method: Cross-Coupling Reactions of the 2,2-Difluorovinylzinc–TMEDA Complex with
Alkenyl, Alkynyl, Allyl, and Benzyl Halides”, J. Fluorine Chem. 2015, 170, 29–37.
120. Kinoshita, H.; Kizu, R.; Inoue, G.; Fujimoto, M.; Saito, M.; Ichikawa, J.; Hosomi, A.;
Miura, M. “Platinum-Catalyzed Allylation of Carbon Electrophiles with Alkenylsilanes”,
Tetrahedron Lett. 2015, 56, 713–716.
121. Fuchibe,

K.;

Bando,M.;

Takayama,

R.;

Ichikawa,

J.

“Organocatalytic,

Difluorocarbene-Based S-Difluoromethylation of Thiocarbonyl Compounds”, J. Fluorine
Chem. 2015, 171, 133–138.
122. Fuchibe, K.; Morikawa, T.; Shigeno, K.; Fujita, T; Ichikawa, J. “Pinpoint-FluorinatedPhenacenses: New Synthesis and Solubility Enhancement Strategies”, Org. Lett. 2015, 17,1126–1129.
123. Fujita, T.; Watabe, Y.; Ichitsuka, T.; Ichikawa, J. “Ni-Catalyzed Synthesis of Fluoroarenes
via [2+2+2] Cycloaddition Involving α-Fluorine Elimination”, Chem. Eur. J. 2015, 21,13225–13228.
124. Ichitsuka, T.; Fujita, T.; Ichikawa, J. “Nickel-Catalyzed Allylic C(sp3)–F Bond Activationof Trifluoromethyl Groups via β-Fluorine Elimination: Synthesis of Difluoro-1,4-dienes”,
ACS Catal. 2015, 5, 5947–5950.

125. Fuchibe, K.; Morikawa, T.; Ueda, R.; Okauchi, T.; Ichikawa, J. “Pinpoint-FluorinatedPhenanthrene Synthesis Based on C–F Bond Activation of Difluoroalkenes”, J. Fluorine
Chem. 2015, 179, 106–115.
126. Fujita, T.; Arita, T.; Ichitsuka, T.; Ichikawa, J. “Catalytic Defluorinative [3+2]Cycloaddition of Trifluoromethylalkenes with Alkynes via Reduction of Nickel(II)Fluoride Species”, Dalton Trans. 2015, 44, 19460–19463.
127. Suzuki, N.; Fujita, T.; Ichikawa, J. “Method for the Synthesis of Dibenzo[g,p]Chrysenes:
Domino Friedel−Crafts-Type Cyclization of Difluoroethenes Bearing Two Biaryl Groups”,
Org. Lett. 2015, 17, 4984–4987.
(“Facile Method for the Synthesis of Dibenzo[g,p]chrysenes,” Synfacts 2015, 11, 1266.)
128. Aono, T.; Sasagawa, H.; Fuchibe, K.; Ichikawa, J. “Regioselective Synthesis of
Derivatives:

α,α-Difluorocyclopentanone

DominoNickel-Catalyzed

Difluorocyclopropanation/Ring Expansion Sequence of Silyl Dienol Ethers”, Org. Lett.
2015, 17, 5736–5739.

2016
129. Fujita, T.; Sugiyama, K.; Sanada, S.; Ichitsuka, T.; Ichikawa, J. “Platform for
Ring-FluorinatedBenzoheterole

Derivatives:

Palladium-Catalyzed

Regioselective

1,1-Difluoroallylation and Heck Cyclization”, Org. Lett. 2016, 18, 248–251.
(“Palladium-Catalyzed Regioselective 1,1-Difluoroallylation and Heck Cyclization,”
Synfacts 2016, 12, 264.)130. Kinoshita, H.; Kizu, R.; Horikoshi, M.; Inoue, G.; Fujimoto, M.; Saito, M.; Ichikawa, J.;
Hosomi, A.; Miura, K. “Regioselective Allylation of Carbon Electrophiles with
Alkenyl-silanes under Dual Catalysis by Cationic Platinum(II) Species”, Synthesis 2016,
48, 520–534.
131. Fujita, T.; Watabe, Y.; Yamashita, S.; Tanabe, H.; Nojima, T.; Ichikawa, J.
“Silver-Catalyzed Vinylic C–F Bond Activation: Synthesis of 2-Fluoroindoles fromο-Sulfonamido-β,β-difluorostyrenes”, Chem. Lett. 2016, 45, 964–966. [Editor’s Choice]132. Fuchibe, K.; Aono, T.; Hu, J.; Ichikawa, J. “Copper(I)-Catalyzed [4 + 1] Cycloaddition of
Silyl

DienolEtherswith

SodiumBromodifluoroacetate:

β,β-Difluorocyclopentanone Derivatives”, Org. Lett. 2016, 18, 4502–4505.

Accessto133. Suzuki, N.; Fujita, T.; Amsharov, K. Y.; Ichikawa, J. “Aluminium-mediated Aromatic C–
F Bond Activation: Regioswitchable Construction of Benzene-fused Triphenylene
Frameworks”, Chem. Commun. 2016, 52, 12948–12951. [Cover Picture]
134. Fuchibe, K.; Abe, M.; Oh, K.; Ichikawa, J. “Preparation of 1,1-Difluoroallenes by
Difluorovinylidenation of Carbonyl Compounds”, Org. Synth. 2016, 93, 352–366.

2017135. Fujita, T.; Takahashi, I.; Hayashi, M.; Wang, J.; Fuchibe, K.; Ichikawa, J. “Facile
Synthesis of Polycyclic Aromatic Hydrocarbons: Brønsted Acid-Catalyzed Dehydrative
Cycloaromatization of Carbonyl Compounds in 1,1,1,3,3,3-Hexafluoropropan-2-ol”, Eur.
J. Org. Chem. 2017, 2, 262–265.
136. Fuchibe, K.; Takayama, R.; Yokoyama, T.; Ichikawa, J. “Regioselective Synthesis of
α-Fluorinated Cyclopentenones by Organocatalytic Difluorocyclopropanation andFluorine-Directed and Fluorine-Activated Nazarov Cyclization”, Chem. Eur. J. 2017, 23,
2831–2838.
137. Fujita, T.; Takazawa, M.; Sugiyama, K.; Suzuki, N.; Ichikawa, J. “Domino C–F Bond
Activation of CF3 Group: Synthesis of Fluorinated Dibenzo[a,c][7]annulenes from
2-Trifluoromethyl-1-alkenes and 2,2'-Diceriobiaryls”, Org. Lett. 2017, 19, 588–591.
138. Saito, K.; Ikeda, T.; Yamamura, Y.; Saitoh, H.; Hishida, M.; Kobayashi, Y.; Fujita, T.;
Ichikawa, J. “Cell-quintupling: Structural phase transition in a molecular crystal, bis(trans-4-butylcyclohexyl) methanol”, J. Chem. Phys. 146, 074503 (2017)139. Takahashi, I.; Hayashi, M.; Fujita, T.; Ichikawa, J. “Brønsted Acid-catalyzed Tandem
Cycloaromatization of Naphthalene-based Bisacetals: Selective Synthesis of ortho-Fused
Six-hexagon Benzenoids”, Chem. Lett. 2017, 46, 392–394.
140. Fuchibe, K.; Hatta, H.; Oh, K.; Oki, R.; Ichikawa, J. “Lewis Acid-Promoted Single C–F
Bond Activation of the CF3 Group: SN1'-type 3,3-Difluoroallylation of Arenes with
2-Trifluoromethyl-1-alkenes”, Angew. Chem. Int. Ed. 2017, 56, 5890–5893.
141. Watabe, Y.; Kanazawa, K.; Fujita, T.; Ichikawa, J. “Nickel-Catalyzed Hydroalkenylationof Alkynes via C–F Bond Activation: Synthesis of 2-Fluoro-1,3-dienes”, Synthesis 2017,49, 3569–3575.
142. Fuchibe, K.; Imaoka, H.; Ichikawa, J. “Synthesis of Pinpoint-Fluorinated Polycyclic
Aromatic Hydrocarbons: Benzene Ring Extension Cycle Involving Microwave-Assisted
SNAr Reaction”, Chem. Asian J. 2017, 12, 2359–2363.

[Cover Picture] (Chem. Asian J. 2017, 12, 2332–2332.)
143. Takayama, R.; Yamada, A.; Fuchibe, K.; Ichikawa, J. “Synthesis of Sulfanylated
Difluoroalkenes:

Electrophilic

DifluoromethylidenationofDithioesters

with

Difluorocarbene”, Org. Lett. 2017, 19, 5050–5053.
144. Fuchibe, K.; Shigeno, K.; Zhao, N.; Aihara, H.; Akisaka, R.; Morikawa, T.; Fujita, T.;
Yamakawa, K.; Shimada, T.; Ichikawa, J. “Pinpoint-fluorinated Polycyclic Aromatic
Hydrocarbons (F-PAHs): Syntheses of Difluorinated Subfamily and Their Properties”, J.
Fluorine Chem. 2017, 203, 173–184.
145. Fujita, T.; Kinoshita, R.; Takanohashi, T.; Suzuki, N.; Ichikawa, J. “Ring-Size-Selective
Construction of Fluorine-Containing Carbocycles via Intramolecular Iodoarylation of
1,1-Difluoro-1-alkenes”, Beilstein J. Org. Chem. 2017, 13, 2682–2689.

2018
146. Fuchibe, K.; Takayama, R.; Aono, T.; Hu, J.; Hidano, T.; Sasagawa, H.; Fujiwara, M.;
Miyazaki, S.; Nadano, R.; Ichikawa, J. “Regioselective Syntheses of FluorinatedCyclopentanone Derivatives: Ring Construction Strategy Using Transition-Metal–
Difluorocarbene Complexes and Free Difluorocarbene”, Synthesis 2018, 50, 514–528.
147. Fuchibe,

K.;

Takayama,

α,α-Difluorocyclopentanone

R.;

Ichikawa,

J.

“Metal-free

Derivatives

Synthesis

viaofRegioselective

Difluorocyclopropanation/VCP Rearrangement of Silyl Dienol Ethers”, ARKIVOC 2018,

ⅱ, 72–80.
148. Fujita, T.; Konno, N.; Watabe, Y.; Ichitsuka, T.; Nagaki, A.; Yoshida, J.; Ichikawa, J.
“Flash Generation and Borylation of 1-(Trifluoromethyl)vinyllithium Toward Synthesis ofα-(Trifluoromethyl)styrenes”, J. Fluorine Chem. 2018, 207, 72–76.
149. Fuchibe, K.; Ichikawa, J. “Fluorine-Directed and -Activated Nazarov Cyclizations:
Selective Synthesis of Fluorinated Cyclopentenones”, Chim. Oggi, 2018, 36(3), 36–39.
150. Fujita, T.; Morioka, R.; Arita, T.; Ichikawa, J. “sp3 Carbon–Fluorine Bond Activation in
2,2-Difluorohomoallylic Alcohols via Nucleophilic 5-endo-trig Cyclisation: Synthesis of
3-Fluorinated Furan Derivatives”, Chem. Commun. 2018, 54, 12938–12941.
[Cover Picture] (Chem. Commun. 2018, 54, 12938–12938.)
151. Fuchibe, K.; Oki, R.; Hatta, H.; Ichikawa, J. “Single C–F Bond Activation of the CF3Group with a Lewis Acid: CF3-Cyclopropanes as Versatile 4,4-Difluorohomoallylating
Agents”, Chem. Eur. J. 2018, 24, 17932–17935.

2019152. Fujita, T.; Hattori, M.; Matsuda, M.; Morioka, R.; Jankins, T. C.; Ikeda, M.; Ichikawa, J.
“Nucleophilic 5-endo-trig cyclization of 2-(trifluoromethyl)allylic metal enolates andenamides: Synthesis of tetrahydrofurans and pyrrolidines bearing exo-difluoromethylene
units”, Tetrahedron 2019, 75, 36–46.
153. Fuchibe, K.; Tsuda, N.; Shigeno, K.; Ichikawa, J. “Construction of Pinpoint-FluorinatedBenzothiophene

Frameworks

Using

Palladium-Catalyzed

Cyclizationof

ο-(Fluorovinyl)phenyl-substituted Thiophenes”, Heterocycles 2019, 99, 1196–1216.
154. Fujita, T.; Ide, K.; Jankins, T. C.; Nojima, T.; Ichikawa, J. “Synthesis of 3(Trifluoromethyl)indoles

via

Oxidative

Cyclizationofο-Sulfonamido-α-(trifluoromethyl)styrenes”, Asian J. Org. Chem. 2019, 8, 637–640.
[Cover Picture] (Asian J. Org. Chem. 2019, 8, 564–564.)
155. Fuchibe,

K.;

Watanabe,S.;

Takao,

G.;

Ichikawa,

J.

“Synthesisof(Difluoromethyl)naphthalenes by Ring Construction Strategy: C–C Bond Formation on
the Central Carbon of 1,1-Difluoroallenes via Pd-Catalyzed Insertion”, Org. Biomol. Chem.
2019, 17, 5047–5054.
156. Takahashi, I.; Fujita, T.; Shoji, N.; Ichikawa, J. “Brønsted Acid-Catalysed Hydroarylationof Unactivated Alkynes in Fluoroalcohol–Hydrocarbon Biphasic System: Construction of
Phenanthrene Frameworks”, Chem. Commun. 2019, 55, 9267–9270.
[Cover Picture] (Chem. Commun. 2019, 55, 9219–9219.)
157. Fuchibe, K.; Takao, G.; Takahashi, H.; Ijima, S.; Ichikawa, J. “Methylarene-Based PAH
Synthesis via Domino Cyclization of 1,1-Difluoro-1-alkenes”, Bull. Chem. Soc. Jpn. 2019,92, 2019–2029.

2020
158. Kubo, T.; Fujita, T.; Ichikawa, J. “Nickel-catalyzed [4 + 2] Cycloaddition of Styrenes with
Arynes via 1:1 Cross-coupling: Synthesis of 9,10-Dihydrophenanthrenes”, Chem. Lett.
2020, 49, 264–266.
159. Fuchibe, K.; Abe, M.; Sasaki, M.; Ichikawa, J. “Gold-Catalyzed Electrophilic Activationof 1,1-Difluoroallenes: α- and γ-Selective addition of Heteroatom Nucleophiles”, J.
Fluorine Chem. 2020, 232, 109452.

160. Fuchibe, K.; Abe, M.; Idate, H.; Ichikawa, J. “Fluorinated Phenanthrenes as Aryne
Precursors: PAH Synthesis Based on Domino Ring Assembly Using 1,1-Difluoroallenes”,
Chem. Asian J. 2020, 15, 1384–1392.
[Cover Picture] (Chem. Asian J. 2020, 15, 1181.)161. Fuchibe, K.; Fushihara, T.; Ichikawa, J. “Synthesis of Ring-Fluorinated Thiophene
Derivatives Based on Single C–F Bond Activation of CF3-Cyclopropanes: Sulfanylationand 5-endo-trig Cyclization”, Org. Lett. 2020, 22, 2201–2205.
162. Morioka, R.; Fujita, T.; Ichikawa, J. “Facile Synthesis of 2-Fluorobenzofurans: 5-endo-trig
Cyclization of β,β-Difluoro-o-hydroxystyrenes”, Helv. Chim. Ata 2020, in press.
163.
164.