１．Department of Virology Ⅰ8) Watanabe S， Ueda N， Iha K， Joseph SM，Fujii H，Phillip A，Mizutani T， Maeda K，Yamane D，Azab W，

1) Tobiume M, Sato Y, Katano H, Nakajima N, Tanaka K,

Kato K， Kyuwa S，Tohya Y，Yoshikawa Y， Akashi H.

Noguchi A, Inoue S, Hasegawa H, Iwasa, Y., Tanaka J,Detection of a new bat gammaherpesvirus in the Philippines.

Hayashi H, Yoshida S, Kurane I, Sata T. Rabies virus

Virus Genes 39:90-93, 2009.

dissemination in neural tissues of autopsy cases due to rabiesimportedintoJapanfromthePhilippines:

9) Sunohara M，Morikawa S，Murata H，Fuse A，Sato I.

immunohistochemistry. Pathology International 59:555-566,

Modulation mechanism of c-Mpl promoter activity in2009.

megakaryoblastic cells. Okajimas Folia Anatomica Japonica
86:89-91, 2009.

2) Sah OP, Subedi S, Morita K, Inoue S, Kurane I, Pandey
BD. Serological study of dengue virus infection in Terai

10) Iizuka I， Saijo M， Shiota T， Ami Y， Suzaki Y，region, Nepal. Nepal Medical College Journal 11:104-106,

Nagata N， Hasegawa H， Sakai K， Fukushi S， Mizutani

2009.

T， Ogata M， Nakauchi M， Kurane I， Mizuguchi M，Morikawa S. Loop-mediated isothermal amplification-based3) Kurane I. BSL4 facilities in anti-infectious diseasediagnostic assay for monkeypox virus infections. Journal ofmeasures. Journal of Disaster Research 4:352-355, 2009.

Medical Virology 81:1102-1108, 2009.

4) Kurane I: The emerging and forecasted effect of climate

11) Yamao T， Eshita Y， Kihara Y， Satho T， Kuroda M，change on human health. Journal of Health ScienceSekizuka T， Nishimura M， Sakai K， Watanabe S， Akashi

55:865-869, 2009.

H， Rongsriyam Y， Komalamisra N， Srisawat R， Miyata
T， Sakata A， Hosokawa M， Nakashima M， Kashige N，5) Kurosawa Y, Kurane I, Yamamoto A. Observation of

Miake F， Fukushi S， Nakauchi M， Saijo M， Kurane I，Japanese

ceramic

Morikawa S ， Mizutani T. Novel virus discovery fromhydroxyapatite by scanning electric microscopy. Medicine

field-collected mosquito larvae using an improved system forand Biology 153:607-610, 2009.

rapid determination of viral RNA sequences (RDV ver4.0).

encephalitis

virusparticles

onArchives of Virology 154:153-158, 2009.
6) Saijo M, Ami Y，Suzaki Y，Nagata N，Iwata N， Hasegawa
H，Iizuka I，Shiota T，Sakai K，Ogata M，Fukushi S， Mizitani

12) Nakamura S， Yang CS， Sakon N， Ueda M， Tougan

T，Sata T，Kurata T，Kurane I，Morikawa S. Virulence andT， Yamashita A， Goto N， Takahashi K， Yasunaga T，pathophysiology of the Congo Basin and West African strains

Ikuta K， Mizutani T， Okamoto Y， Tagami M， Moritaof monkeypox virus in nonhuman primates. Journal ofR， Maeda N， Kawai J， Hayashizaki Y， Nagai Y， Horii

General Virology 90:2266-2271，2009.

T， Iida T， Nakaya T. Direct metagenomic detection of viralpathogens in nasal and fecal specimens using an unbiased7) Satoh T， Dieng H， Mizutani T, Eshita Y，Miyata T，

high-throughput sequencing approach. PLoS ONE 4:e4219,

Talukder P， Kashige N， Ahmad AH, Miake F. Fluorescence2009.

can be used to trace the fate of exogenous micro-organisms
inside the alimentary tract of mosquitoes. Journal of13) Sakai K， Ueno Y， Ueda S， Yada K， Fukushi S， Saijo

Parasitology and Vector Biology 1:13-18, 2009.

M， Kurane I， Mutoh K， Yoshioka K， Nakamura M，Takehara K， Morikawa S， Mizutani T. Novel reovirus
1isolation from an Ostrich (Struthio camelus) in Japan.

Development of an antibody-dependent enhancement assay

Veternary Microbiology 134:227-232, 2009.

for dengue virus using stable BHK-21 cell lines expressing
FcγRIIA. Journal of Virological Methods 163:205-209, 2010.

14) Nakauchi M， Fukushi S， Saijo M， Mizutani T， Ure
AE ， Romanowski V ，Kurane I ， Morikawa S.

21) Lim CK， Nishibori T， Watanabe K， Ito M， Kotaki

Characterization of monoclonal antibodies to Junin virus

A， Tanaka K， Kurane I， Takasaki T. Chikungunya virus

nucleocapsid protein and application to the diagnosis ofisolated from a returnee to Japan from Sri Lanka: isolation ofhemorrhagic fever caused by South American arenaviruses.

two sub-strains with different characteristics. American

Clinical and Vaccine Immunology 16:1132-1138, 2009.

Journal of Tropical Medicine and Hygine 81:865-868, 2009.

15) Mizutani T. Characterization of signaling pathways in22) Takasaki T， Kotaki A，Lim CK，Tajima S，Omatsu T，cells infected with SARS-CoV.

in Host Gene Responses toMeng Ling Moi ， Kurane I. Arbovirus infections: theRNA Viral Infection. Edited by Yang D. World Scientificchallenges of controlling an ever-present enemy. Journal ofPublishing, pp321-344, 2009.

Disaster Research，4 : 322-328, 2009.

16) Shirato K, Mizutani T.

Replication， transcription，and translation of coronaviruses.

23)Aoyama I，Uno K，Yumisashi T，Takasaki T， Lim CK，

in Viral Genomes. Edited

Kurane I，Kase T， Takahashi K. A case of Chikungunya

by Freng Z and Long M) Nova Publishers, pp.159-167, 2009.

fever imported from India to Japan， follow-up of specific
IgM and IgG Antibodies over a 6-month period. Japanese17) Eshita Y， Higashihara J， Onishi M， Mizuno M，Journal of Infectious Diseases 63:65-66, 2010.

Yoshida J， Takasaki T， Kubota N， Onishi Y. Mechanismof introduction of exogenous genes into cultured cells using24) Hoi ML，Lim CK，Kotaki A，Takasaki T， Kurane I.

DEAE-dextran-MMA graft copolymer as non-viral gene

Discrepancy in Dengue virus neutralizing antibody titers

carrier. Molecules 14:2669-83, 2009.

between plaque reduction neutralizing tests with Fcγ receptor(FcγR)-negative and FcγR-expressing BHK-21 cells. Clinical18) Takahashi H， Ohtaki N， Maeda-Sato M， Tanaka M，and Vaccine Immunology 17:402-407， 2010.

Tanaka K， Sawa H， Ishikawa T，Takamizawa A， TakasakiT， Hasegawa H， Sata T， Hall WW， Kurata T， Kojima

25) Yamamoto K， Matumoto K， Lim CK， Moi ML，A. Effects of the number of amino acid residues in the signal

Kotaki A，Takasaki T. Chikungunya fever from Malaysia.

segment upstream or downstream of the NS2B-3 cleavage site

Internal Medicine 49:501-5, 2010.

on production and secretion of prM/M-E virus-like particlesof West Nile virus. Microbes and Infections 11:1019-28,

26) Tajima S，Nerome R，Nukui Y，Kato F，Takasaki T，

2009.

Kurane I. A single mutation in the Japanese encephalitis virus
E protein (S123R) increases its growth rate in mouse19) Moi ML，Lim CK，Takasaki T，Kurane I. Involvement ofneuroblastoma cells and its pathogenicity in mice. Virology

the Fcγ receptor IIA cytoplasmic domain in antibody

396:298-304, 2010.

enhancement of dengue virus infection. Journal of General
Virology 91:103-111, 2010.

27) Moi ML，Takasaki T，Kotaki A，Tajima S, Lim CK,Omatsu T, Kurane I. Dengue importations into Japan from20) Moi ML，Lim CK，Kotaki A，Takasaki T， Kurane I.

Bali.
2

ProMed,March29,2010,

availablefrom

[http://www.promedmail.org］，archive no.20100329.09. 2010.

Tsutsui Y， Kurane I， Inoue N. Characterization of the guinea
pig cytomegalovirus genome locus that encodes homologs of28) Takasaki T, Moi ML, Kotaki A, Sakamoto M, Kobayashi K,

human cytomegalovirus major immediate-early genes ，Kurane I. Dengue importations into Japan from Tanzania.

UL128， and UL130. Virology 391:99-106, 2009.

ProMed,March23,2010,

availablefrom[http://www.promedmail.org］， archive no. 20100323.0922.

36) Kurashina Y，Liu X，Kato C，Inoue N，Saneyoshi M，2010.

Yamaguchi T. Influence of 3'-azido-2', 3'- dideoxyguanosine
tretmenton telomere length in human telomerase-immortalized29) Nukuzuma S， Nakamichi K， Nukuzuma C， Takegami

human fibroblast cells. Nucleic Acids Symposium Series

T. Inhibitory effect of serotonin antagonists on JC virus

53:249-250, 2009.

propagation in a carrier culture of human neuroblastoma cells.
Microbiology and Immunology 53: 496-501，2009.

37) Otsuka T， Gomi Y， Inoue N， Uchiyama M.

Varicellatransmitted from a healthy vaccinee with herpes zoster， Japan.
30) Nukuzuma S， Kameoka M， Sugiura S， Nakamichi K，Emerg Infec Dis 15:1702-1703, 2009.

Nukuzuma C， Miyoshi I， Takegami T. Archetype JC virus
efficiently

propagatesinkidney-derivedcells

stably38) Nozawa N，Fang-Hoover J，Tabata T， Maidji E，Pereira

expressing HIV-1 Tat. Microbiology and Immunology 53:

L.

621-628，2009.

neutralizing activity in maternal circulation enriched in the

Cytomegalovirus-specific,

high-avidity

IgG

withfetal bloodstream. Journal of Clinical Virology Suppl 4:S58-63,
31) Yagi T ， Hattori H ， Ohira M ， Nakamichi K ，2009.

Takayama-Ito M， Saijo M， Shimizu T， Ito D， Takahashi
K， Suzuki N. Progressive multifocal leukoencephalopathy39) Kasem S， Yu MH， Yamada S， Kodaira A， Matsumuradeveloped in incomplete Heerfordt syndrome ， a rare

T， Tsujimura K， Madbouly H， Yamaguchi T， Ohya K，manifestation of sarcoidosis ， without steroid therapy

Fukushi H.

responding

determinant of Equine herpesvirus 1 (EHV-1) in the mouse

tocidofovir.

Clinical

Neurology

andThe ORF37 (UL24) is a neuropathogenicity

Neurosurgery 112:153-156，2010.

encephalitis model.

Virology 400:259-270, 2010.

32)Morimoto K ， Saijo M. Imported rabies cases and40) Okuno K， Takashima K， Kanai K， Ohashi M， Hyuga

preparedness for rabies in Japan. Journal of Disaster ResearchR， Sugihara H， Kuwamoto S， Kato M， Sano H， Sairenji

4:346-357，2009.

T， Kanzaki S， Hayashi K.

Epstein-Barr virus can infectrabbits by the intranasal or perioral route: An animal model for33) Saijo M， Morikawa S， Kurane I. Diagnostic systems fornatural primary EBV infection in humans.

viral hemorrhagic fevers and emerging viral infections

Medical Virology 82:977-986, 2010.

Journal ofprepared in the National Insititute of Infectious Diseases.
Journal of Disaster Research 4:315-321， 2009.

41) Hanaoka N， Matsutani M， Kawabata H， YamamotoS， Fujita H， Sakata A， Azuma Y， Ogawa M， Takano34) Saijo M. Emerging and re-emerging infection threats toA，Watanabe H，Kishimoto T， Shirai M，Kurane I，Andosociety. Journal of Disaster Research 4:291-297，2009.

S. Diagnostic assay for Rickettsia japonica.
Infectious Diseases 15:1994-1997, 2009.

35) Yamada S， Nozawa N， Katano H， Fukui Y， Tsuda M，
3Emerging42) Takano A， Muto M， Sakata A， Ogasawara Y， AndoS， Hanaoka N， Tsurumi M， Sato F， Nakamura N， Fujita
H， Watanabe H， Kawabata H.

Relapsing fever spirochetein seabird tick, Japan. Emerging Infectious Diseases
15:1528-1530, 2009.

43) Matsui T， Kobayashi J， Satoh H， Fujimoto T， Okabe
N， Ando S， Kishimoto T, Yamamoto S. Surveillancerecognition, and reporting of Tsutsugamushi disease (Scrubtyphus) and Japanese spotted fever by general practice clinics
in Miyazaki Prefecture, 2007. Journal of Infection andChemoterapy 15:269-272, 2009.

44) Kishimoto T, Ando S, Numazaki K, Ouchi K, Yamazaki T,Nakahama C. Assay of Chlamydia pneumoniae-specific IgM
antibodies by ELISA method―reduction of non-specificreaction and resetting of serological criteria by measuring
IgM antibodies.

Japanese Journal Infectious Diseases

62:260-264, 2009.

45) Hanaoka N, Sakata A, Takano A, Kawabata H, Watanabe
H, Kurane I, Kishimoto T, Ando S. Development of a
pUC19-based recombinant plasmid to serve as a positive
control in PCR for Orientia tsutsugamushi. Microbiology andImmunology 53: 305-308,2009.

46) Ogawa M, Shinkai-Ouchi F, Matsutani M, Uchiyama T,Hagiwara K, Hanada K, Kurane I, Kishimoto T. Shotgunproteomics of Orientia tsutsugamushi. Clinical Microbiology
and Infection Suppl 2:239-240, 200947) Uchiyama T， Ogawa M， Kishi M，Yamashita T，Kishimoto T and Kurane I. Restriction of the growth oftyphus group rickettsiae in tick cells. Clinical Microbiology
and Infection Suppl 2:332-3, 20094