氏名

所属

職名

取得学位

専門分野

主な論文・著作・業績①Takebe N, Tanno K, Ohmomo H, Hangai M, Oda T, Hasegawa Y, Takanashi N, Sasaki R, Shimizu A, Sasaki A,Sakata K, Sasaki M, Ishigaki Y. Weight Gain After 20 Years of Age is Associated with Unfavorable Lifestyle andIncreased Prevalence of Metabolic Disorders. Diabetes Metab Syndr Obes. 2021;14:2065-2075.
②Satoh K, Nagasawa K, Takebe N, Kinno H, Shozushima M, Onodera K, Oda T, Hasegawa Y, Satoh J, Ishigaki Y.
Adiponectin Paradox More Evident in Non-Obese Than in Obese Patients with Diabetic MicrovascularComplications. Diabetes Metab Syndr Obes. 2023 Jan 23;16:201-212.
③Shozushima M, Mori F, Yashiro S, Todate Y, Oda T, Nagasawa K, Hasegawa Y, Takebe N, Sasaki M, Ishigaki Y.

石垣泰

内科学講座糖尿病・代謝・内分泌内科分野

教授

医学博士

代謝学(糖代謝）

Evaluation of High Intracranial Plaque Prevalence in Type 2 Diabetes Using Vessel Wall Imaging on 7 T Magnetic
Resonance Imaging. Brain Sci. 2023;13(2):217.
④Matsushita Y, Hasegawa Y, Takebe N, Onodera K, Shozushima M, Oda T, Nagasawa K, Honma H, Nata K, SasakiA, Ishigaki Y. Serum C-X-C motif chemokine ligand 14 levels are associated with serum C-peptide and fatty liver
index in type 2 diabetes mellitus patients. J Diabetes Investig. 2021, 12(6):1042-1049.
⑤Oda T, Satoh M, Nagasawa K, Sasaki A, Hasegawa Y, Takebe N, Ishigaki Y. The Effects of Imeglimin on the Daily
Glycemic Profile Evaluated by Intermittently Scanned Continuous Glucose Monitoring: Retrospective, SingleCenter, Observational Study. Diabetes Ther. 2022 Jul 27. doi: 10.1007/s13300-022-01298-w.
①Okada K, Kotani K, Ebihara K, Yamazaki H, Ishibashi S. Predictors of response to ipragliflozin treatment inpatients with type 2 diabetes mellitus. Int J Clin Pharmacol Ther. 54(12): 1004-1008. 2016
② Kario K, Okada K, Kato M, Nishizawa M, Yoshida T, Asano T, Uchiyama K, Niijima Y, Katsuya T, Urata H, Osuga
J, Fujiwara T, Yamazaki S, Tomitani N, Kanegae H. 24-Hour Blood Pressure-Lowering Effect of an SGLT-2 Inhibitorin Patients with Diabetes and Uncontrolled Nocturnal Hypertension: Results from the Randomized, PlaceboControlled SACRA Study. Circulation. 2019; 139: 2089-2097

岡田健太

内科学講座糖尿病・代謝・内分泌内科分野

特任教授

医学博士

代謝学・内分泌学③ Okada K, Hoshide S, Kato M, Kanegae H, Ishibashi S, Kario K. Safety and efficacy of empagliflozin in elderly
Japanese patients with type 2 diabetes mellitus: A post hoc analysis of data from the SACRA study. J Clin
Hypertens (Greenwich). 2021, Apr;23(4):860-869.
④Okada K, Kotani K, Yagyu H, Ando A, Osuga J, Ishibashi S. Effects of treatment with liraglutide on oxidativestress and cardiac natriuretic peptides levels in patients with type 2 diabetes mellitus. Endocrine. 47(3): 962-964,
2014⑤Okada K, Kotani K, Yagyu H, Ishibashi S. Eicosapentaenoic acid/arachidonic acid ratio and smoking status inelderly patients with type 2 diabetes mellitus. Diabetol Metab Syndr. 6(1): 85 2014

①Hasegawa Y, Takahashi Y, Kezuka Y, Obara W, Kato Y, Tamura S, Onodera K, Segawa T, Oda T, Sato M, Nata K,Nonaka T, Ishigaki Y. Identification and Analysis of a Novel NR0B1 Mutation in Late-Onset Adrenal Hypoplasia
Congenita and Hypogonadism. J Endocr Soc. 2020; 5(2):bvaa176.
②Matsui M, Takahashi Y, Takebe N, Takahashi K, Nagasawa K, Honma H, Oda T, Ono M, Nakagawa R, Sasai T,Togashi H, Hangai M, Kajiwara T, Taneichi H, Ishigaki Y, Satoh J. Response to the dipeptidyl peptidase-4 inhibitors
in Japanese patients with type 2 diabetes might be associated with a diplotype of two single nucleotide
polymorphisms on the interleukin-6 promoter region under a certain level of physical activity. J Diabetes Investig.
2015 Mar;6(2):173-81.

高橋義彦

内科学講座糖尿病・代謝・内分泌内科分野

准教授

医学博士

③Takarabe D, Rokukawa Y, Takahashi Y, Goto A, Takaichi M, Okamoto M, Tsujimoto T, Noto H, Kishimoto M,代謝学・内分泌学

Kaburagi Y, Yasuda K, Yamamoto-Honda R, Tsukada K, Honda M, Teruya K, Kajio H, Kikuchi Y, Oka S, Noda M.
Autoimmune diabetes in HIV-infected patients on highly active antiretroviral therapy. J Clin Endocrinol Metab.
2010; 95:4056-60.
④Takahashi Y, Noda M, Tsugane S, Kuzuya T, Ito C, Kadowaki T. Prevalence of diabetes estimated by plasma
glucose criteria combined with standardized measurement of HbA1c among health checkup participants onMiyako Island, Japan. Diabetes Care 2000; 8: 1092-1096.
⑤Takahashi Y, Kadowaki H, Ando A, Quin JD, MacCuish AC, Yazaki Y, Akanuma Y, Kadowaki T. Two aberrant
splicings caused by mutations in the insulin receptor gene in cultured lymphocytes from a patient with RabsonMendenhall's syndrome. J.Clin.Invest. 1998; 101: 588-594.
①Hasegawa Y. New perspectives on obesity-induced adipose tissue fibrosis and related clinical manifestations.
Endocrine Journal. 2022 Jul 28;69(7):739-748②Hasegawa Y, Takahashi Y, Kezuka Y, Obara W, Kato Y, Tamura S, Onodera K, Segawa T, Oda T, Sato M, Nata K,
Nonaka T, Ishigaki Y. Identification and Analysis of a Novel NR0B1 Mutation in Late-Onset Adrenal Hypoplasia
Congenita and Hypogonadism. J Endocrine Society. 2020 Nov 13;5(2): bvaa176.
③Matsushita Y, Hasegawa Y, Takebe N, Onodera K, Shozushima M, Oda T, Nagasawa K, Honma H, Nata K, Sasaki

長谷川豊

内科学講座糖尿病・代謝・内分泌内科分野

特任准教授

医学博士

代謝学（糖尿病）

A, Ishigaki Y. Serum C-X-C motif chemokine ligand 14 levels are associated with serum C-peptide and fatty liver
index in type 2 diabetes mellitus patients. J Diabetes Investig. 2020 Oct 15.
④Hasegawa Y, Ikeda K, Chen Y, Alba DL, Stifler D, Shinoda K, Hosono T, Maretich P, Yang Y, Ishigaki Y, Chi J,Cohen P, Koliwad SK, Kajimura S.Repression of Adipose Tissue Fibrosis through a PRDM16-GTF2IRD1 Complex
Improves Systemic Glucose Homeostasis.Cell Metabolism. 2018 Jan 9;27(1):180-194⑤Altshuler-Keylin S, Shinoda K, Hasegawa Y, Ikeda K, Hong H, Kang Q, Yang Y, Perera RM, Debnath J, Kajimura S.
Beige Adipocyte Maintenance Is Regulated by Autophagy-Induced Mitochondrial Clearance.Cell Metab. 2016 Aug
24. pii: S1550-4131(16)30378-3.

① Fujita N, Baba T, Tomiyama T, Kodama T, Kato N. Hyperinsulinaemia and blood pressure withinsulinoma. BMJ. 1992;304(6835):1157.
② Hangai M, Takebe N, Honma H, Sasaki A, Morita A, Nakano R, Togashi H, Nakagawa R, Oda T, Matsui M, SasaiT, Nagasawa K, Kajiwara T, Takahashi K, Takahashi Y, Satoh J, Ishigaki Y. Association of Advanced Glycation End
Products with coronary Artery Calcification in Japanese Subjects with Type 2 Diabetes as Assessed by Skin
Autofluorescence. Journal of atherosclerosis and thrombosis. 2016;23(10):1178-1187.
③ Murai T, Takebe N, Nagasawa K, Todate Y, Nakagawa R, Nakano R, Hangai M, Hasegawa Y, Takahashi Y,

武部典子

内科学講座糖尿病・代謝・内分泌内科分野

講師

医学博士

代謝学・内分泌学

Yoshioka K, Ishigaki Y. Association of epicardial adipose tissue with serum level of cystatin C in type 2 diabetes.
PLoS One. 2017;12(9):e0194623.
④Matsushita Y, Hasegawa Y, Takebe N, Onodera K, Shozushima M, Oda T, Nagasawa K, Honma H, Nata K, SasakiA, Ishigaki Y. Serum C-X-C motif chemokine ligand 14 levels are associated with serum C-peptide and fatty liver
index in type 2 diabetes mellitus patients. J Diabetes Investig. 2021;12(6):1042-1049.
⑤Takebe N, Tanno K, Ohmomo H, Hangai M, Oda T, Hasegawa Y, Takanashi N, Sasaki R, Shimizu A, Sasaki A,Sakata K, Sasaki M, Ishigaki Y. Weight Gain After 20 Years of Age is Associated with Unfavorable Lifestyle andIncreased Prevalence of Metabolic Disorders. Diabetes Metab Syndr Obes. 2021;14:2065-2075.
①Yutaka H, Yoshihiko T, Yuichiro K, Wataru O, Yoichiro K, Shukuko T, Ken O, Toshie S, Tomoyasu O, Marino Sa,Koji N, Takamasa N, Yasushi I. Identification and Analysis of a Novel NR0B1 Mutation in Late-Onset Adrenal
Hypoplasia Congenita and Hypogonadism. J Endocr Soc. 5, 1-10, 2021.
②Yuki M, Fumitaka T, Toshie S, Kozo T, Kazuyoshi I, Kiyomi S, Masaki O, Shinichi O, Kuniaki O, Koichi A andMotuyki N. Sex differences in the influence of elevated serum uric acid levels for cardiovascular risk in the general
population with normal renal function. JIMA 72, 145-155, 2020.
③Nakamura M, Tanaka F, Segawa T, Takahashi T, Matsuura Y, Sakai T, Nishiyama O, Niiyama M, Onoda T,

瀬川利恵

内科学講座糖尿病・代謝・内分泌内科分野

講師

医学博士

Koshiyama M, (on behalf of Northern Iwate Heart Disease Registry Consortium) . Temporal Trends in the
代謝学・内分泌学Incidence and Clinical Features of Acute Myocardial Infarction in a Japanese Rural Area From 2006 to 2014. Circ J
2017; 81: 1854–1861.
④ Koeda Y, Tanaka F, Segawa T, Ohta M, Ohsawa M, Tanno K, Makita S, Ishibashi Y, Itai K, Omama S, Onoda T,Sakata K, Ogasawara K, Okayama A, Nakamura M. Comparison between urine albumin-to-creatinine ratio andurine protein dipstick testing for prevalence and ability to predict the risk for chronic kidney disease in the general
population (Iwate-KENCO study): a prospective community-based cohort study.BMC Nephrol. 2015;12;17(1):46.
⑤ Toshie S, Motoyuki N, Kazuyoshi I, Toshiyuki O, Akira O, Katsuhiko H. B-type Natriuretic Peptide Levels andRisk Factors for Congestive Heart Failure in a Japanese General Population. Int Heart J. 2005;46(3):465-75.
①Nagasawa K, Kaneko Y, Taneichi H, Ishii M, Masaya M, Honma H, Kakino S, Takahashi K, Yoshioka Y, Satoh J:
Association of decrease in liver triglyceride content with increase in plasma adiponectin levels after pioglitazone
treatment in Japanese patients with type 2 diabetes. J Iwate Med Assoc 62(1): 59-66, 2010.
②Oda T, Satoh M, Nagasawa K, Sasaki A, Hasegawa Y, Takebe N, Ishigaki Y. The Effects of Imeglimin on the Daily

長澤幹

内科学講座糖尿病・代謝・内分泌内科分野

特任講師

医学博士

代謝学（糖尿病）

Glycemic Profile Evaluated by Intermittently Scanned Continuous Glucose Monitoring: Retrospective, SingleCenter, Observational Study. Diabetes Ther. 2022 Jul 27. doi: 10.1007/s13300-022-01298-w.
③Satoh K, Nagasawa K, Takebe N, Kinno H, Shozushima M, Onodera K, Oda T, Hasegawa Y, Satoh J, Ishigaki
Y:Adiponectin Paradox More Evident in Non-Obese Than in Obese Patients with Diabetic MicrovascularComplications.Diabetes Metab Syndr Obes. 2023 Jan 23;16:201-212

①Oda T, Taneichi H, Takahashi K, Togashi H, Hangai M, Nakagawa R, Ono M, Matsui M, Sasai T, Nagasawa K,Honma H, Kajiwara T, Takahashi Y, Takebe N, Ishigaki Y, Satoh J: Positive association of free triiodothyronine withpancreatic β-cell function in people with prediabetes: Diabet Med. 2014 Sep 26.

小田知靖

内科学講座糖尿病・代謝・内分泌内科分野

助教

医学博士

代謝学（糖尿病）②Oda T, Satoh M, Nagasawa K, Sasaki A, Hasegawa Y, Takebe N, Ishigaki Y.The Effects of Imeglimin on the Daily
Glycemic Profile Evaluated by Intermittently Scanned Continuous Glucose Monitoring: Retrospective, SingleCenter, Observational Study.Diabetes Ther. 2022 Sep;13(9):1635-1643. doi: 10.1007/s13300-022-01298-w. Epub
2022 Jul 27.
①Satoshi Yashiro, Hiroyuki Kameda, Ai Chida, Yusuke Todate, Yutaka Hasegawa, Kan Nagasawa, Ikuko Uwano,

八代諭

内科学講座糖尿病・代謝・内分泌内科分野

助教

医学博士

代謝学（糖尿病）

Makoto Sasaki, Kuniaki Ogasawara, Yasushi Ishigaki Evaluation of Lenticulostriate Arteries Changes by 7 T
Magnetic Resonance Angiography in Type 2 Diabetes:Journal of Atherosclerosis and Thrombosis, 2018;25:10671075.
① Togashi H, Takahashi Y, Kajiwara T, Honma H, Nagasawa K, Sasai T, Nakagawa R, Takebe N, Satoh J and冨樫弘文

内科学講座糖尿病・代謝・内分泌内科分野

助教

医学博士

代謝学（糖尿病）

Ishigaki Y. Association of HbA1c variability with diabetic nephropathy and renal dysfunction in Japanese patientswith type 2 diabetes. Journal of Iwate Medical Association Vol. 67, No. 4(October 2015) : 157-70.
①Mari Hangai, Noriko Takebe, Hiroyuki Honma, Atsumi Sasaki,Ai Morita, Rieko Nakano, Hirobumi Togashi, Riyuki

半谷真理

内科学講座糖尿病・助教

代謝・内分泌内科分野（任期付）

Nakagawa,Tomoyasu Oda, Mizue Matsui, Takayoshi Sasai, KanNagasawa, Takashi Kajiwara, Kazuma

医学博士

代謝学（糖尿病）

Takahashi,Yoshihiko Takahashi, Jo Satoh, Yasushi Ishigak:Association of Advanced Glycation End Products withcoronary Artery Calcification in Japanese Subjects with Type 2 Diabetes as Assessed by Skin Autofluorescence,
Journal of atherosclerosis and thrombosis, 23(10), 1178-1187, 2016 Oct 1佐賀敦美

内科学講座糖尿病・助教

代謝・内分泌内科分野（任期付）

代謝学（糖尿病）①千田 愛, 高橋 義彦, 中川 理友紀, 長澤 幹, 川島 智美, 佐藤 まりの, 瀬川 利恵, 高橋 和眞, 石垣 泰

千田愛

内科学講座糖尿病・助教

代謝・内分泌内科分野（任期付）

性HLAハプロタイプを有する膵島関連自己抗体陰性の多腺性自己免疫症候群2型の1例
代謝学（糖尿病）

糖尿病

1型糖尿病疾患抵抗2019：62(9)、514-9②千田 愛、橋本 朋子、松下 百合子、中川 理友紀、小田 知靖、長谷川 豊、武部 典子、石垣 泰：1型糖尿病の血清ア
ディポサイトカイン濃度に影響する因子の検討：Journal of Iwate Medical Association 72(1):11-20、2020