７．Department of Pathology

virus in non-human primates. J Gen Virol 2009,
90:2266-71.

1) Dewan MZ, Tomita M, Katano H, Yamamoto N, Ahmed

8) Kawaguchi A, Orba Y, Kimura T, Iha H, Ogata M, Tsuji

S, Yamamoto M, Sata T, Mori N, Yamamoto N. An HIV

T, Ainai A, Sata T, Okamoto T, Hall WW, Sawa H,

protease

nuclearHasegawa H. Inhibition of the SDF-1alpha-CXCR4 axis

factor-kappaB and inhibits the tumor growth andby the CXCR4 antagonist AMD3100 suppresses theinfiltration of EBV-positive lymphoblastoid B cells. Int

migration of cultured cells from ATL patients andJ Cancer. 2009, 124:622-9.

murineinhibitor,ritonavirtargetsthe2) Takahashi H, Kitagawa Y, Maeda-Satoh M, Hasegawa

lymphoblastoidcells

fromHTLV-I

Taxtransgenic mice. Blood 2009, 114:2961-8.

H, Sawa H, Sata T. Monoclonal antibody and siRNAs9) Ichinohe T, Ainai A, Tashiro M, Sata T, Hasegawa H.

for topoisomerase I suppress telomerase activity.

PolyI:polyC12U adjuvant-combined intranasal vaccineHybridoma (Larchmt) 2009, 28:63-5.

protects mice against highly pathogenic H5N1 influenza

3) Mitsuishi T, Nakatake M, Kaneko T, Ohara K, Kato T,virus variants. Vaccine 2009, 27:6276-9.

Iida, K, Iwabu Y, Tokunaga K, Sata T, Kawana S,10) Morimoto T, Arii J, Tanaka M, Sata T, Akashi H,Yamada O. Evaluation of Telomerase Activity inYamada M, Nishiyama Y, Uema M, Kawaguchi Y.

Nongenital Bowen’s Disease. J Eur Acad Dermatol

Differences in the regulatory and functional effects ofVenereol 2009, 23:668-72.

the Us3 protein kinase activities of herpes simplex virus

4) Takahashi Y, Hasegawa H, Hara Y, Ato M, Ninomiya A,

1 and 2. J Virol 2009, 83:11624-34.

Takagi H, Odagiri T, Sata T, Tashiro M, Kobayashi K.

11) Katano H, Ito H, Suzuki Y, Nakamura T, Sato Y, Tsuji T,

Protective Immunity Afforded by Inactivated H5N1

Matsuo K, Nakagawa H, Sata T. Detection of Merkel(NIBRG-14) Vaccine Requires Antibodies against Bothcell polyomavirus in Merkel cell carcinoma andHemagglutinin and Neuraminidase in Mice. J Infect Dis

Kaposi's sarcoma. J Med Virol 2009, 81:1951-8.
12) Takahashi H, Ohtaki N, Maeda-Sato M, Tanaka M,2009, 199:1629-37.
5) Hayasaka D, Nagata N, Fujii Y, Hasegawa H, Sata T,

Tanaka K, Sawa H, Ishikawa T, Takamizawa A,

Suzuki R, Gould EA, Takashima I, Koike S. Mortality

Takasaki T, Hasegawa H, Sata T, Hall WW, Kurata T,

followingtick-borne

Kojima A. Effects of the number of amino acid residues

encephalitis virus results from a combination of central

in the signal segment upstream or downstream of thenervous system pathology, systemic inflammatory andNS2B-3 cleavage site on production and secretion ofstress responses. Virology 2009, 390:139-50.

prM/M-E virus-like particles of West Nile virus.

peripheral

infectionwith6) Tobiume M, Sato Y, Katano H, Nakajima N, Tanaka K,

Microbes Infect 2009, 11:1019-28.

Noguchi A, Inoue S, Hasegawa H, Iwasa Y, Tanaka J,13) Kitagawa Y, Maeda-Sato M, Tanaka K, Tobiume M,Hayashi H, Yoshida S, Kurane I, Sata T. Rabies virus

Sawa H, Hasegawa H, Kojima A, Hall WW, Kurata T,

dissemination in neural tissues of autopsy cases due toSata T, Takahashi H. Covalent bonded Gag multimers inrabies imported into Japan from the Philippines.

human

immunohistochemistry. Pathol Int 2009, 59:555-66.

Microbiol Immunol 2009, 53:609-20.

immunodeficiency

virus

type-1

particles.

7) Saijo M, Ami Y, Suzaki Y, Nagata N, Iwata N,14) Iwabu Y, Fujita H, Kinomoto M, Kaneko K, Ishizaka Y,Hasegawa H, Iizuka I, Shiota T, Sakai K, Ogata M,Tanaka Y, Sata T, Tokunaga K. HIV-1 accessory protein

Fukushi S, Mizutani T, Sata T, Kurata T, Kurane I,Vpu internalizes cell-surface BST-2/tetherin through

Morikawa S. Virulence and pathophysiology of thetransmembrane interactions leading to lysosomes. J Biol

Congo Basin and West African strains of monkeypox

Chem 2009, 284:35060-72.
115) Hasegawa H, Ichinohe T, Ainai A, Tamura S, Kurata T.

Nakauchi M, Kurane I, Mizuguchi M, Morikawa S.

Development of an inactivated mucosal vaccine for

Loop-mediated

H5N1 influenza virus. Ther Clin Risk Manag 2009,

diagnostic assay for monkeypox virus infections. J Med

5:125-32.

Virol 2009, 81:1102-8.

isothermal

amplification-based16) Ishii K, Hasegawa H, Nagata N, Ami Y, Fukushi S,22) Yoshikawa N, Yoshikawa T, Hill T, Huang C, Watts DM,

Taguchi F, Tsunetsugu-Yokota Y. Neutralizing antibody

Makino S, Milligan G, Chan T, Peters CJ, Tseng CT.

againstDifferential virological and immunological outcome ofsevere

acuterespiratory

syndrome(SARS)-coronavirus spike is highly effective for thesevere

protection of mice in the murine SARS model.

(SARS-CoV) infection in susceptible and resistant

Microbiol Immunol 2009, 53:75-82.

transgenic17) Utachee P, Jinnopat P, Isarangkura-na-ayuthaya P,

acuterespiratory

mice

syndrome-coronavirus

expressing

angiotensin-converting enzyme 2.

Chandimal de Silva U, Nakamura S, Siripanyaphinyo U,

human

J. Virol. 2009,

83(11): 5451-65.

T,23) Yamada S, Nozawa N, Katano H, Fukui Y, Tsuda M,

Sawanpanyalert P, Ikuta K, Auwanit W, Kameoka M.

Tsutsui Y, Kurane I, Inoue N. Characterization of theGenotypic Characterization of CRF01_AE env Genes

guinea pig cytomegalovirus genome locus that encodes

Derived from Human Immunodeficiency Virus Typehomologs

1-Infected Patients Residing in Central Thailand. AIDS

immediate-early genes, UL128, and UL130. Virology

Res Hum Retroviruses 2009, 25:229-36.

2009, 391:99-106.

Wichukchinda

N,Tokunaga

K,

Yasunagaofhumancytomegalovirus

major18) Utachee P, Jinnopat P, Isarangkura-na-ayuthaya P,24) Takahashi-Makise N, Suzu S, Hiyoshi M, Ohsugi T,

Chandimal de Silva U, Nakamura S, Siripanyaphinyo U,Katano H, Umezawa K, Okada S. Biscoclaurine

Wichukchinda

T,alkaloid cepharanthine inhibits the growth of primary

Sawanpanyalert P, Ikuta K, Auwanit W, Kameoka M.

effusion lymphoma in vitro and in vivo and induces

Phenotypic

apoptosis via suppression of the NF-kappaB pathway.

N,studiesTokunagaon

K,

Yasunaga

recombinant

human

immunodeficiency virus type 1 (HIV-1) containing

Int J Cancer 2009, 125:1464-72.

CRF01_AE env gene derived from HIV-1-infected25) Cheng B, Martinez FP, Katano H, Tang Q. Evidence ofpatient, residing in central Thailand. Microbes Infectinability of human cytomegalovirus to reactivate

2009, 11:334-43.

Kaposi's sarcoma-associated herpesvirus from latency

19) Kataoka M, Yamamoto A, Ochiai M, Harashima A,

in body cavity-based lymphocytes. J Clin Virol 2009,

Nagata N, Hasegawa H, Kurata T, Horiuchi Y.

46:244-8.

Comparison of acellular pertussis-based combination

26) Yamazaki J, Mizukami T, Takizawa K, Kuramitsu M,

vaccines by Japanese control tests for toxicities andMomose H, Masumi A, Ami Y, Hasegawa H, Hall W. W,

laboratory models for local reaction. Vaccine 2009, 27:

Tsujimoto H, Hamaguchi I, Yamaguchi K. Identification

1881-8.

of Cancer Stem Cells in a Tax-transgenic (Tax-Tg)20) Dabaghmanesh N, Matsubara A, Miyake A, Nakano K,

Mouse Model of Adult T- Cell Leukemia / lymphoma

Ishida T, Katano H, Horie R, Umezawa K, Watanabe T.

(ATL). Blood 2009, 114:2709-20.
27) Hoshino Y, Katano H, Zou P, Hohman P, Marques A,

Transient inhibition of NF-kappaB by DHMEQ inducescell death of primary effusion lymphoma withoutTyring

HHV-8 reactivation. Cancer Sci 2009, 100:737-46.

administration of valacyclovir reduces the number of21) Iizuka I, Saijo M, Shiota T, Ami Y, Suzaki Y, Nagata N,

Epstein-Barr virus (EBV)-infected B cells but not theHasegawa H, Sakai K, Fukushi S, Mizutani T, Ogata M,

number of EBV DNA copies per B cell in healthy
2SK,

FollmannD,

CohenJI.

Long-term28) Jinnopat P, Isarangkura-na-ayuthaya P, Utachee P,Kitagawa Y, Chandimal de Silva U, Siripanyaphinyo U,Kameoka Y, Tokunaga K, Sawanpanyalert P, Ikuta K,Auwanit W, Kameoka M. Impact of amino acidvariations in Gag and protease of HIV Type 1
CRF01_AE strains on drug susceptibility of virus toprotease inhibitors. J Acquir Immune Defic Syndr 2009,
52:320-8.
29) Dean J, Hashimoto K, Tsuji T, Gautier V, Hall WW,Sheehy N. Functional interaction of HTLV-1 tax proteinwith the POZ domain of the transcriptional repressor
BCL6. Oncogene 2009, 28:3723-34.
30) Abe K. Pathology of hepadna virus infection in humansand animals. Thai J Vet Med 2009, 39:453-5.
31) Abe K, Thung SN, Wu H-C, Tran TT, Hoang PL,Truong KD, Inui A, Jang JJ, Su I-J. Pre-S2 deletionmutants of hepatitis B virus could have an importantrole in hepatocarcinogenesis in Asian children. Cancer
Sci 2009, 100:2249-54.
32) Fukuda S, Iwamaru Y, Imamura M, Masujin K, Shimizu
Y, Matsuura Y, Shu Y, Kurachi M, Kasai K, Murayama
Y, Onoe S, Hagiwara K, Sata T, Mohri S, Yokoyama T,Okada H.: Intraspecies transmission of L-type-like
Bovine Spongiform Encephalopathy detected in Japan.
Microbiol Immunol 2009, 53:704-7.

3