DELab Micro Computed Tomography

For in vivo small laboratory animals and ex vivo samples / μCT-100
High-resolution desktop CT / μCT-100X
 Maximum resolution up to 1μm, fast scan in 2 seconds
 Patented carrier for automatic recognition, one-touch parameter setting
 3D reconstruction for comprehensive insight into the structure of study objects

LifeScience

GeologicalScience

Materials
ScienceFoodScienceRestoring accurate details with3D Micro Computed Tomography system
Delta’s 3D Micro Computed Tomography system is asystem can extract and reconstruct 3D images, andnon-destructive testing instrument designed specifical-

accurately capture the internal physical structure of aly for small target objects, including in vivo small labora-tested object. It helps shorten testing and verification

tory animals, fossil specimens, biological samples,times, identify problems faster, and improve thedrugs, electronic components, metals, and plastics, andefficiency of product development, academic research,more. With computed tomography technology, theand quality management .

Application fields
Life science

Food science In vivo and ex vivo scan New product development

 Whole-body scanning of in vivo small

 Reformulation experiments

laboratory animals

 Changes in food over time Micro structure of the spine Structure and texture Body fat distribution analysis

 Structural effects of ingredients Respiratory, cardiac, and cardiopulmonary

and additives

gated imaging

Bone and teeth research

Geological science Bone disease models

 Structural geology

 Fossil samples

 Building materials

 Endodontic research and root canals

 Geochemistry Bone morphology analysis

 Paleontology

 Density measurement, volume analysis

 3D mineral distribution| 2金質獎

DELab μCT-100
Micro Computed Tomography

For in vivo small laboratory animals
and ex vivo samples• 1 (One) Touch : Automatic recognizable animal bed
for FOV selection.
• 2 Seconds : Fast scan mode
• 2 μm : High-resolution image• Independent heated airflow and anesthesia system
help to maintain the stable vital signs of the animal• Equipped with tube voltage range :40-90 kVp , 50W

One touch auto-setting• Automatic recognizable animal bed
Rat-size bed:80(ф) mm x 200(L) mm
Mouse-size bed:40(ф) mm x 200(L) mm
Ex vivo bed:10(ф) mm x 200(L) mm• Automatic multi-filter and
FOV modes selection:
RatMouse
Ex vivo
Ultra-High Resolution

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2 sec. Fast-scanCube-shielding

Syringe Pump*

Self-shielding:

The built-in syringe pump can automatically inject a contrast

Cube radiation protection

agent during scanning, and it also offers manual injection modefor different experimental requirements. This significantly
increases the diversity of experimental operations .

*Estimated to be launched in 2022Q4

Capsule-style Multifunctional Chamber System
The chamber features an easy-to-remove replaceable bed support, a top cover design for escape prevention, an embedded surveillance camera, body temperature measurement, and smart recognition functions. It also includes an independent anesthesia gas andheating system to stabilize the animal’s vital signs while providing physiological monitoring to monitor the animal’s status in real time.

Controllable warming
chamber

Anesthesia gas
absorption system

Anti-Escape Cover: This design prevents small

Embeddedanimals that are not completely anaesthetizedenables real-time observation of small

from escaping during the experiment.

animals during imaging. Respiratory signals

LEDCamera:

Thecameracan be detected using camera images anddisplayed on the interface.

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DELab μCT-100X
Micro Computed Tomography

High-resolution desktop CT• Accurately capture detailed internal structures• Transmission X-ray tube for 1-μm high-quality images• Efficient image reconstruction for 3D modeling• Designed for safety, stability, and availability• Non-destructive inspection

Sealed Transmission Tubeand CCD X-Ray Detector

Phase Contrast Technology forSharper Image Edges

The sealed transmission tube and CCD X-ray detector

The μCT-100X uses in-line phase contrast imaging technology

produce 1-μm high-resolution images through characteris-to strengthen image edge in low-Z or low attenuation materials,

tics of high power output, small focal spot, and less focal

without the need to purchase expensive optical accessories.

spot drift.

Sharper Edges

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Patented Carrier Ensures Stable Image Acquisition
360◦ Degree Rotation Carrier
Patented anti-twist and anti-vibration design ensure stable carrier
360-degree rotation during image acquisition.

Control the Rotate Angle and Speed
Motor optimization allows accurate control over the rotation speed andangle, further ensuring stable image quality.

Radiation Shield.
No Need for an Additional Shielding Room or Control AreaFeatures Comprehensive Self-Shielding
The lead and lead glass design ensure that radiation stays
inside the machine, with a reading of <1 μSv/h detectablewithin 10 cm of the X-ray system.
This frees up space by not needing an extra lead room ordesignated X-ray area. Moreover, the lead glass allows users
to monitor internal operations in a radiation-protectedenvironment.

InterlockTo prevent radiation leakage, the X-ray system is fitted with asensor that prevents operation while the door is not closed
perfectly. Furthermore, the X-ray will turn off immediately if
the door is opened during operation.

Automatic InternalTemperature Regulation
The internal temperature is automatically regulated tomaintain consistent conditions. This protects the object
under inspection from being affected by temperature
variations that would influence image quality.

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Efficient Image Reconstruction for 3D Modeling
Rapid Scanning
Parameter Setup

1

Instant 2D/3DImage Capture

2

Multi-Size Carrier for a Wide Range

Easy Calibrationof ApplicationsImage calibration is easily performed using commonly usedDifferent carrier options are provided to accommodate theparameters to obtain the best image quality.

resolution requirements and size of the tested object. Carrier
size is identified using a patented technology to achieve

Image Capture and Real-Time Monitoring System

collision prevention.

The graphic operating system is integrated with real-timemonitoring, enabling easy system configuration and 2D/3D
image acquisition to monitor the status of the tested object inDefault Application Mode, Complete Parameter

real time during the scanning process.

Settings in One Click
Default detection mode can beconfigured according to carriersize, and carrier recognition andpositioning

areautomaticallycompleted in one click, thus
simplifying a complex process.

Optimal 3D
Reconstruction

3Inspection
Completed

3D Image Batch Reconstruction

3D Imaging and Measurement

A batch of images can be loaded for batch reconstruction after

Image interpretation is assisted by built-in image flip/rotation,

setting parameters individually or collectively , thereby simplify-measurement

ing the testing process.

probe, and rendering/visual setting tools.

Local 3D Image Reconstruction
An area of interest can be selected for 3D reconstruction to
reduce the overall file size, thus accelerating the reconstruction
process .

Multi-Section Display
Problems can be quickly identified by cropping 3D images inany direction to simultaneously display multiple images at therequired angle and section view.

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labeling,grayscaleadjustment,

coordinate

Imaging Technology
Image stitching
Image stitching technology uses Delta-developed algorithms to seamlessly stitch segments of circular cone beam CT images.

Before stitching

After stitching

Sub-volume reconstruction

Dose estimation

A reconstruction algorithm reconstructs local high-resolution

Signals received by the image detector are used to estimate

images to optimize the original image.

the radiation dose exposed to the imaged object.

Dose Rate
Acc. Dose2 μm voxel size
(Delta)15 μm Ex vivo mode

Zoom in by interpolation(Others)

Image-based gating
Signal analysis can be performed on captured images without additional sensors or ECGs. Image data are used toreconstruct pulmonary and two-phase/four-phase cardiac and cardiopulmonary gated images.

Result of image-based
gatingResult of generalimaging|8In Vivo Imaging

DELab μCT-100

DELab μCT-100
NU/NU Nude mouse
Cell line: CT26 colorectal cancer cell
Resolution: 22.5 μm, Scan time: 20 seconds

Complete presentation of an embryo’s
skeletal development in a pregnant
female mouse
Resolution: 22.5 μm

DELab μCT-100 four-phase cardiopulmonary gated images
Image-based gating algorithm is used to capture heart and lung images at different times for reconstruction without
needing to place sensors or ECGs on the small animal.

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DELab μCT-100
Image-based gating captures images ofthe lung in a static state, and prevents
blurred images due to breathing
movement, thus providing a moreaccurate interpretation of the disease
area and state of the lung.

General imaging mode

Image-based gating mode

DELab μCT-100 Whole-body angiography
Whole-body angiography is performed using acontrast agent made specifically for small animals.
Whole-body images can be obtained with two-stepscanning.
Resolution: 44.9 μm
Scan time: 20 seconds
Number of scan steps: 2Carotidarteries
HeartLiver6.5cm

DELab μCT-100 Turtle
Surface rendering is combined with volume rendering.
Images A and B show the sagittal and coronal planes of the chest and trachea, respectively.
Image C shows the pattern on the turtle’s plastron.
Resolution: 22.5 μm, Scan time: 20 seconds

ABC

4.28cm| 10

High-Resolution CT Image

A1.4cmDELab μCT-100 Mouse femur

DELab μCT-100X Dwarf seahorse, 40 kVp,resolution: 7.5μm
A combination of 2D and 3D images shows the characteristics of the seahorse,
including the interior and exterior, biological features, structure, and number of bones.

DELab μCT-100X

9 μm pixel ultra-high resolution
Image A: Transverse and 3D sections
show details of the femur.

DELab μCT-100X

DELab μCT-100X

Sand dollars

Zebrafish

Trilobite fossil

40 kVp, 0.3 mmAl
Resolution: 3 μm

60 kVp, 0.3 mmAl
Resolution: 5 μm

40 kVp, 0.5 mmAl
Resolution: 3 μm

1.2cm

2.8cm

AnalysisDual-Energy Image Analysis

High Energy

Low Energy

The dual-energy imaging program on the interface can be used to automatically capture two sets of images with different energy levels. Users canselect the default dual-energy parameter setting for optimal fat and muscle
comparisons. Alternatively, imaging parameters can be adjusted as required
for experiments.

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With the dual-energy image analysis software,
the tissue of interest can be selected anddistinguished using different colors.

Bone Morphology

Select ROI

Segment bone image

Confirm bone cavity range

Distinguish cortical bone
and trabecula area

Bone morphology analysis calculates total
volume (TV), bone volume (BV), ratio ofbone and tissue volume (BV/TV), trabecula
thickness (Tb.Th), and number of trabeculabones (Tb.N), etc.
Thickness of trabecula

Osteoporotic bone

Normal bone

Bone Density Calculation

Body Fat Analysis

QRM’s HA Phantom and the intuitive interface are used to analyze thescanned bone image and calculate bone density.

Using optimal scanning parameters, users
can capture enhanced images for body fatanalysis. The analysis software thencalculates the volume of body fat as apercentage of the section image.

Batch Scanning and HU Calculation
The complex calibration process is simplified, allowing users to easily
complete routine calibration works during non-working hours or when time
permits during experiments .

Body fat ratio: 0.36 (Obese mouse)

Body fat ratio: 0.16 (Normal mouse)| 12Specifications

DELab μCT-100
Micro Computed Tomography

For in vivo small laboratory animals
and ex vivo samples
MCL-090AF75P0 X

Model
X-Ray System
X-Ray Tube

40-90 kV, 50 W

X-Ray Detector

1536 × 1944, 14-bits, CMOS detector

Filter

0.5 mmAl, 1.0 mmAl, 1.5 mmAl, 0.2 mmCu and no filter, total 5 types

Inspection Performance
Scan Mode3DResolution

9 μm, 15 μm, 22.5 μm, 44.9 μm

Field of View

10 mm, 23 mm, 40 mm, 80 mm

Reconstruction Size

1944 × 1944 × 1536 pixel (Single scan)

Image Output Format

Raw, DICOM

Mechanical Design
Sample carriers

3 carriers

Acceptable Sample Size

Rat-size bed: 80 (ф) x 200(L) mm,(Diameter × Height)

Mouse-size bed: 40(ф)x 200(L) mm,
Ex vivo bed: 10(ф) x 200(L) mm

Acceptable Sample Weight< 5 kgDimension, Weight

88 × 150 × 150 cm, < 950 kg

Power100-240V~/50-60Hz/5.85 A

Radiation Safety< 1 μSv/h within 10 cm of the X-ray system (while scanning)

Accessories
 System operation and image acquisition software Image reconstruction software
 3D image analysis software

Equipment (Standard) Image acquisition and processing computer Camera

Others (Optional) Anesthesia system
 Uninterrupted power system (UPS)

150 cmSoftware (Standard)

150 cm13 | www.deltaww.com

88 cm

DELab μCT-100X
Micro Computed Tomography

High-resolution desktop CTModel

MCI-110

MCI-100

X-Ray System
X-Ray Tube

40-110 kV, 16 W, 2 μm focal spot size at 2W

40-100 kV, 20W, 5 μmv focal spot size at 2W

X-Ray Detector

4032 × 2688, 14-bits, CCD detector

2944 × 2352, 14-bits, CMOS flat panel detector

Filter

0.3 mmAl, 0.5 mmAl, 1.0 mmAl, 0.1 mmCu+0.3 mmAl,

0.3 mmAl, 0.5 mmAl, 1.0 mmAl, 0.1 mmCu+0.3 mmAl,

0.2 mmCu+1.0 mmAl and no filter, total 6 types

0.2 mmCu+1.0 mmAl and no filter, total 6 types

Scan Mode2D, 3D2D, 3DResolution

1 μm, 3 μm, 5 μm, 7.5 μm

5 μm, 15 μm, 33 μm

1 μm: 4(ф) x 2.5(L), 3 μm: 12(ф) x 7.5(L),5 μm: 14.5(ф) x 11(L), 15 μm: 44(ф) x 33(L),5 μm: 20(ф) x 12.5(L), 7.5 μm: 30(ф) x 18.5 (L) mm

33 μm: 97(ф) x 72.5(L) mm

Reconstruction Size

4032 × 4032 × 2688 pixel (Single scan)

2944 × 2944 × 2352 pixel (Single scan)

Image Output Format

 2D: JPG, BMP, TIF, PNG, RAW 3D: TIF, RAW, DICOM

 2D: JPG, BMP, TIF, PNG, RAW 3D: TIF, RAW, DICOM

Sample carriers

4 carriers

3 carriers

Acceptable Sample Size

1 μm: 11(ф) x 19(L), 3 μm: 19(ф) x 35(L),5 μm: 19(ф) x 35(L), 15 μm: 39(ф) x 44(L),(Diameter × Height)

5 μm: 24(ф) x 43(L), 7.5 μm: 39(ф) x 44(L) mm

33 μm: 83(ф) x 146(L) mm

Acceptable Sample Weight< 1 kg< 5 kgDimension, Weight

96 × 95.5 × 67.5 cm (W × H × D ), 430 kg

96 × 95.5 × 67.5 cm (W × H × D ), 433 kg

PowerAC 110/220 V ± 10%, 50/60 Hz, 15A

AC 110/220 V ± 10%, 50/60 Hz, 15A

Radiation Safety< 1 μSv/h within 10 cm of the X-ray system (while scanning)

Inspection Performance

Field of View (ф x L)

Mechanical DesignAccessories
Software (Standard) System operation and image acquisition software Image reconstruction software
 3D image analysis software Image acquisition and processing computer Camera

Others (Optional)

 Loadable over 1000 kg, anti-vibration table Uninterrupted power system (UPS)

94~95.5 cm

Equipment (Standard)

96 cm

67.5 cm| 14

Delta Electronics, Inc.

16 Tungyuan Rd., Chungli Industrial Zone, Taoyuan City 32063, Taiwan
TEL : +886 3 452 6107
E-mail : x.ray@deltaww.com

www.deltaww.com

2022 / 11