Poster Presentations
P-001–055: October 23 (Wednesday) 17:30–19:00
P-001

Chemo-enzymatic synthesis of glycopeptide bearing multiple glycans by orthogonal protection strategy

P-002

Synthesis of α-trifluoromethyl α-amino acids and conformational analysis of their peptides

Tomohiro Tanaka, Kenji Osumi, Akio Matsuda, Mamoru Mizuno (The Noguchi Institute)Misuzu Ikeda1, Takuya Kasae1, Atsushi Ueda1, Makoto Oba1, Mitsunobu Doi2, Masakazu Tanaka1(1Graduate School of Biomedical Sciences, Nagasaki University, 2Osaka University of Pharmaceutical
Sciences)
P-003

Development of chemical synthesis for peptidomimetic based on a chloroalkene dipeptide isostere andits application to a cyclic peptide
Takuya Kobayakawa, Hirokazu Tamamura (Institute of Biomaterials and Bioengineering, Tokyo Medical
and Dental University)

P-004

Serine-containing oligopeptides of 6 amino-acid residues show self-assembly based on antiparallel βsheet
Akira Takahashi, Kazuki Kishimoto, Hisayuki Morii, Atsushi Kameyama (Faculty of Engineering,
Kanagawa University)

P-005

Synthesis and structural characteristics of boron-containing azapeptides
Kota Miyata1, Airi Narita1, Ryota Fujisawa1, Makoto Roppongi2, Shingo Tamesue1, Satoshi Ito1, Toru
Oba1 (1Graduate School of Engineering, Utsunomiya University, 2Advanced Instrumental Analysis
Department, Center for Industry-University Innovation Support, Utsunomiya University)

P-006

Synthesis of p-borono-L-phenylalanine (BPA)-like aza-amino acids
Kota Miyata1, Airi Narita1, Ryota Fujisawa1, Makoto Roppongi2, Shingo Tamesue1, Satoshi Ito1, Toru
Oba1 (1Department of Material and Environmental Chemistry, Graduate School of Engineering,
Utsunomiya University, 2Advanced Instrumental Analysis Department, Center for Industry-University
Innovation Support, Utsunomiya University)

P-007

Asymmetric Michael addition reaction using peptide-catalysts with a thiourea moiety
Kazuki Sato, Tomohiro Umeno, Atsushi Ueda, Masakazu Tanaka (Graduate School of Biomedical
Sciences, Nagasaki University)

P-008

Miniaturization of a peptide structure that selectively recovers gold element
Tatsuki Tonoda1, Masahiro Asano2, Kin-ya Tomizaki1 (1Depertment of Materials Chemistry, Ryukoku
University, 2Department of Environmental Solutions Technology, Ryukoku University)

P-009

Synthetic study on (Z)-chloroalkene dipeptide isosteres containing an α,α-disubstituted amino acid
Saki Imai1, Yuki Kodama2, Kohei Sato1, Nobuyuki Mase1,2, Tetsuo Narumi1,2 (1Graduate School ofIntegrated Science and Technology, Shizuoka University, 2Graduate School of Science and Technology,
Shizuoka University)

P-010

Solid-phase synthesis and biological evaluation of cherimolacyclopeptide E
Yuka Yoshida, Yuichi Masuda (Graduate School of Bioresources, Mie University)(10)P-011

Chemical synthesis of insulin-like androgenic gland factor from the freshwater prawn Macrobrachiumrosenbergii
Hidekazu Katayama1, Hiromichi Nagasawa2 (1Department of Applied Biochemistry, School ofEngineering, Tokai University, 2Department of Applied Biological Chemistry, Graduate School of
Agricultural and Life Sciences, The University of Tokyo)

P-012

Synthetic study of Ralstonin A and Ralstoamide A: Construction of cyclic fragment and preparation of
β-amino fatty acid Ahod moiety using Soloshonok ligand
Kie Oyama1, Vadim A. Soloshonok2,3, Hiroki Moriwaki4, Hiroyuki Konno1 (1Graduate School of Scienceand Engineering, Yamagata University, 2Department of Organic Chemistry I, Faculty of Chemistry,
University of the Basque Country UPV/EHU, 3IKERBASQUE, Basque Foundation for Science, 4Hamari
Chemicals Ltd)

P-013

A method for searching novel cell penetrating peptides using T7 phege random peptides library andhigh-throuput sequencing
Momoko Omura, Shohei Kosugi, Yosuke Nakashima, Yukiko Kato, Yuji Ito (Department of Chemistry
and Bioscience, Graduate School of Science and Engineering, Kagoshima University)

P-014

Genome- and mass spectrometry-guided discovery of ralstoamides A and B from Ralstonia
solanacearum species complex
Shoko Komatsu1, Kouhei Ohnishi2, Kenji Kai1 (1Graduate School of Life and Environmental Sciences,
Osaka Prefecture University, 2Research Institute of Molecular Genetics, Kochi University)

P-015

Purification and characterization of a bioactive venom peptide from Clavus davidgilmouri (family
drillidae)
Victor Chua1,2, Joanna Gajewiak2, Maren Watkins2, Samuel S. Espino2, Iris Bea Ramiro1,2, Carla Omaga1,
Louis Paolo Carpio1, Alexander Fedosov3, Helena Safavi-Hemami2, Lilibeth Salvador-Reyes1,
Baldomero M. Olivera2, Gisela P. Concepcion1 (1Marine Science Institute, University of the Philippines,
2

School of Biological Sciences, University of Utah, 3Russian Academy of Sciences, Severtsov Institute of

Ecology and Evolution)
P-016

Isolation and synthesis of u-Conotoxin from Conus striolatus
Abe Ernest Johann E. Isagan1, Iris Bea L. Ramiro1, Ansyl Marie B. Naraga2, Oliver John V. Belleza2,
Julita S. Imperial3, Baldomero M. Oliver3, Aaron Joseph L. Villaraza2, Gisela P. Concepcion1 (1The
Marine Science Institute, University of the Philippines, 2Institute of Chemistry, University of thePhilippines, 3Institute of Biology, University of Utah)

P-017

Highly efficient synthesis of pyrrole-imidazole amide sequence for application to DNA-binding
polyamides
Takahiko Murata1, Shohei Yamamoto2, Akira Nishiyama1 (1Pharma & Supplemental Nutrition Solutions
Vehicle, KANEKA CORPORATION, 2KANEKA AMERICAS HOLDING, INC.)

P-018

Application of ring-closing metathesis in water using unprotected peptide
Shun Masuda, Shugo Tsuda, Taku Yoshiya (Peptide Institute, Inc.)

P-019

Oxidation reaction of proline containing peptide by iron complex catalysis
Arata Kawakami1, Masaki Kobayashi1, Yasushi Obora1,2, Yoshiaki Hirano1,2 (1Faculty of Chemistry,
Materials and Bioengineering, Kansai University, 2Organization for Research and Development of
Innovative Science and Technology, Kansai University)(11)

P-020Lossen rearrangement-mediated preparation of N-glyoxylyl peptide without addition of oxidant
Daishiro Kobayashi, Kodai Nishida, Tsubasa Inokuma, Akira Shigenaga, Akira Otaka (Institute of
Biomedical Sciences and Graduate School of Pharmaceutical Sciences, Tokushima University)

P-021

An external-thiol-free peptide C-terminus thioesterification method using cysteinylprolyl imide (CPI)
peptideKoki Nakatsu1, Masafumi Yanase1, Gosuke Hayashi2, Akimitsu Okamoto1,3 (1Department of Chemistry
and Biotechnology, Graduate School of Engineering, The University of Tokyo, 2Department of
Biomolecular Engineering, Graduate School of Engineering, Nagoya University, 3Research Center for
Advanced Science and Technology, The University of Tokyo)

P-022

Chemical splicing of unprotected peptides towards protein semisynthesis
Kento Iritani, Ryo Okamoto, Yoko Amazaki, Yuta Maki, Yasuhiro Kajihara (Department of Chemistry,
Graduate School of Science, Osaka University)

P-023

A novel amphipathic cell-penetrating peptide based on the N-terminal glycosaminoglycan binding
region of human apolipoprotein E
Yuki Tamura1, Mana Kotani1, Takashi Ohgita1, Yuki Takechi-Haraya2, Kazuchika Nishitsuji3, Kenji
Uchimura4, Koki Hasegawa5, Kumiko Sakai-Kato6, Kenichi Akaji7, Hiroyuki Saito1 (1Department ofBiophysical Chemistry, Kyoto Pharmaceutical University, 2Division of Drugs, National Institute of
Health Sciences, 3Department of Biochemistry, Wakayama Medical University, 4Unité de Glycobiologie
Structurale et Fonctionnelle, 5Center for Instrumental Analysis, Kyoto Pharmaceutical University,
6

P-024

Kitasato University, 7Department of Medicinal Chemistry, Kyoto Pharmaceutical University)

Development of antimicrobial peptide foldamers based on Magainin2 sequence
Chihiro Goto1,2, Motoharu Hirano2, Katsuhiko Hayashi2, Takashi Misawa2, Yutaka Kikuchi2, Yukiko
Kudo2, Yosuke Demizu1,2 (1Graduate School of Medical Life Sciences, Yokohama City University,
2

P-025

National institute of Health Sciences)

Development of a membrane curvature-sensing peptide based on a structure–activity correlation study
Kenichi Kawano, Masaya Ogushi, Toshihiro Masuda, Shiroh Futaki (Institute for Chemical Research,
Kyoto University)

P-026

Studies on identification of active sites in oxytocin as a positive allosteric modulator of µ opioid receptor
Takaaki Mizuguchi1, Ami Yamazaki1, Hideki Takahashi1,2, Yuki Yoshida2,3, Kanako Miyano2, Yasuhito
Uezono2, Hideaki Fujii1 (1Laboratory of Medicinal Chemistry, School of Pharmacy, Kitasato University,
2

Division of Cancer Pathophysiology, National Cancer Center Research Institute, 3Laboratory of

Molecular Pathology and Metabolic Disease, Faculty of Pharmaceutical Sciences, Tokyo University of
Science)
P-027

Design and biophysical evaluation of β-hairpin peptides derived from single-domain VHH antibodies
Koichi Yamamoto1, Makoto Nakakido1,2, Daisuke Kuroda1,2,3, Satoru Nagatoishi4, Jumpei Morimoto2,
Shinsuke Sando1,2, Kouhei Tsumoto1,2,3,4 (1Department of Bioengineering, School of Engineering, The
University of Tokyo, 2Department of Chemistry & Biotechnology, School of Engineering, The
University of Tokyo, 3Medical Device Development and Regulation Research Center, School ofEngineering, The University of Tokyo, 4Institute of Medical Science, The University of Tokyo)

P-028

Unnatural peptides that prefer specific helical structures can be synthesized by β-residues with acyclohexene-ring constraint
Jieun Lee, Seonho Shin, Soo Hyuk Choi (Department of Chemistry, Yonsei University)(12)

P-029Controlofhandednessbysubstituting

residuesof

β-peptides

containing

cis-2-

aminocycloheptanecarboxylic acid
Yonghan Kim, Ho Yang Son, Soo Hyuk Choi (Department of Chemistry, Yonsei University)
P-030

Effect of tryptophan residues on the stability of ion channel formed by peptides
Keita Shigedomi1, Satoshi Osada1, Masoud Jelokhani-Niaraki2, Hiroaki Kodama1 (1Department ofChemistry and Applied Chemistry, Faculty of School and Engineering, Saga University, 2Department ofChemistry and Biochemistry, Wilfrid Laurier University)

P-031

De novo design of pore-forming α-helical peptides with GXXXG and GXXXXXXG motifs
Masataka Usami, Keisuke Shimizu, Yusuke Sekiya, Ryuji Kawano (Department of Biotechnology andLife Science, Tokyo University of Agriculture and Technology)

P-032

Design and synthesis of β-strand conformation-fixed peptides inhibiting aggregation of amyloid βprotein
Fumiya Tanaka, Kana Shibata, Yuichi Masuda (Graduate School of Bioresources, Mie University)

P-033

Structural parameters contributing to the ability of amphipathic peptides to induce membrane
curvature
Motoki Nishimura1, Toshihiro Masuda1, Sergii Afonin2, Kenichi Kawano1, Anne S. Ulrich2,3, Shiroh
Futaki1 (1Institute for Chemical Research, Kyoto University, 2Institute of Biological Interfaces (IBG-2),
Karlsruhe Institute of Technology (KIT), 3Institute of Organic Chemistry and CFN, KIT)

P-034

Development of leucyl-3-epi-deoxynegamycin derivative with a potent readthrough activity
Noriko Omura, Keisuke Hamada, Akihiro Taguchi, Keiju Shimano, Chikashi Sawada, Kentaro
Takayama, Atsuhiko Taniguchi, Yoshio Hayashi (Department of Medicinal Chemistry, School of
Pharmacy, Tokyo University of Pharmacy and Life Sciences)

P-035

De novo design of β-hairpin peptide to construct nanopore structure in lipid membrane
Keisuke Shimizu1, Shungo Sakashita2, Yoshio Hamada2, Kenji Usui2, Batsaikhan Mijiddorj3, Izuru
Kawamura3, Ryuji Kawano1 (1Department of Life Science and Biotechnology, Tokyo University ofAgriculture and Technology, 2Faculty of Frontiers of Innovative Research in Science and Technology,
Konan University, 3Department of Materials Science and Engineering, Yokohama National University)

P-036

Evolution of structure and stability for tetramerization domain in tumor suppressor protein p53
Natsumi Nakagawa, Fuki Kudoh, Junya Wada, Rui Kamada, Toshiaki Imagawa, Kazuyasu Sakaguchi(Laboratory of Biological Chemistry, Department of Chemistry, Faculty of Science, Hokkaido
University)

P-037

Toward an in vitro selection for constrained peptides that bind to transcription factor SMAD3 but not
SMAD2
Linh Khanh Huynh1,2, Kato Mitsuyasu2, Peter ten Dijke3,4, Christopher John Hipolito4,5 (1Master’s
Program in Medical Science, Graduate School of Comprehensive Human Sciences, University ofTsukuba, 2Laboratory of Experimental Pathology, Faculty of Medicine, University of Tsukuba, 3Oncode
Institute, Cell and Chemical Biology, Leiden University Medical Center, 4Laboratory of Cancer
Signaling, Faculty of Medicine, University of Tsukuba, 5Peptide Core Facility, Transborder Medical
Research Center, University of Tsukuba)(13)

P-038Structure-activity relationship study of an antibody-binding peptide focused on glycine residue at theposition 9
Akane Fukuda1, Kyohei Muguruma1, Rento Osawa1, Satoshi Kishimoto2, Akihiro Taguchi1, Kentaro
Takayama1, Atsuhiko Taniguchi1, Yuji Ito2, Yoshio Hayashi1 (1Department of Medicinal Chemistry,
Tokyo University of Pharmacy and Life Sciences, 2Department of Chemistry and Bioscience, Graduate
School of Science and Engineering, Kagoshima University)

P-039

Evaluation of the ring size of macrocyclic inhibitors for BACE1
Takuya Otani1, Kazuya Kobayashi1, Yasunao Hattori2, Kenichi Akaji1 (1Department of Medicinal
Chemistry, Kyoto Pharmaceutical University, 2Center for Instrumental Analysis, Kyoto Pharmaceutical
University)

P-040

Structure-activity relationship studies of small molecular anti-HIV-1 compounds targeting a dipeptidesite of HIV-1 capsid proteins
Masaki Kurakami1, Takuya Kobayakawa1, Masaru Yokoyama2, Tsutomu Murakami3, Moemi Kaneko1,
Osamu Kotani2, Hironori Sato2, Hirokazu Tamamura1 (1Institute of Biomaterials and Bioengineering,Tokyo Medical and Dental University, 2Infectious Disease Surveillance Center, National Institute of
Infectious Diseases, 3AIDS Research Center, National Institute of Infectious Diseases)

P-041

Development of HIV-1 fusion inhibitors based on the C34 dimer derived from an HIV-1 envelope
protein gp41
Kento Ebihara1, Yuzuna Honda1, Takuya Kobayakawa1, Tsutomu Murakami2, Hirokazu Tamamura1(1Institute of Biomaterials and Bioengineering, Tokyo Medical and Dental University (TMDU), 2AIDS
Research Center, National Institute of Infectious Diseases)

P-042

Development of peptidomimetic inhibitors for aggregation of amyloid beta
Yuki Watanabe1, Takuya Kobayakawa1, Atsuhiko Taniguchi2, Yoshio Hayashi2, Hirokazu Tamamura1(1Institute of Biomaterials and Bioengineering, Tokyo Medical and Dental University (TMDU), 2Schoolof Pharmacy, Tokyo University of Pharmacy and Life Sciences)

P-043

Directed evolution of a novel cyclic peptoid-peptide chimera for cancer treatment
Rina Iwamoto1, Daisuke Horiuti1, Mizuki Yamamoto1, Takashi Kawakami1,2 (1Department of
Biotechnology, Faculty of Life and Environmental Sciences, University of Yamanashi, 2JST, PRESTO)

P-044

Development of novel protein G-binding peptide tags for recombinant protein purification
Keita Tsukamoto1, Yukio Takamori1, Mizuki Yamamoto1, Takashi Kawakami1,2 (1Department of
Biotechnology, Faculty of Life and Environmental Sciences, University of Yamanashi, 2JST, PRESTO)

P-045

Electrophysiological analysis of Aβ42 channel formation in planar lipid bilayer imitating nervous cellmembrane
Yuri Numaguchi, KeisukeShimizu, Kaori Tsukakoshi, Kazunori Ikebukuro, Ryuji Kawano (Departmentof Life Science and Biotechnology, Tokyo University of Agriculture and Technology)

P-046

Synthetic study on full-length hepatitis B virus core protein
Keisuke Aoki1, Shugo Tsuda2, Shinsuke Inuki1, Hiroaki Ohno1, Taku Yoshiya2, Shinya Oishi1 (1Graduate
School of Pharmaceutical Sciences, Kyoto University, 2Peptide Institute, Inc.)(14)

P-047Development of Borealin derived peptides for survivin targeting cancer treatment
Iori Nozaki1, Takeshi Fuchigami1, Natsumi Ishikawa1, Yusuke Miyanari2, Motohiro Yamauchi3, Riru
Yamashita1, Yumi Ikeda1, Sakura Yoshida1, Morio Nakayama1 (1Department of Hygienic Chemistry,
Graduate School of Biomedical Sciences, Nagasaki University, 2Okazaki Institute for Integrative
Bioscience, 3Department of Radiation Biology and Protection, Atomic Bomb Disease Institute, Nagasaki
University)

P-048

Development of novel substrate identification method using oncogenic phosphatase PPM1D using theH107-mutants
Shunta Imai1, Seiya Yagi1, Megumi Ikeura1, Kazuhiro Furukawa2, Yoshiro Chuman1 (1Laboratory of
Biological Chemistry, Departoment of Chemistry, Faculty of Science, Niigata University, 2Cell
Regulation Laboratory in Biochemistry, Departoment of Chemistry, Faculty of Science, Niigata
University)

P-049

Tumor cell imaging using MMP-2 activatable-on peptide- and tumor homing peptide-conjugateddendrimer
Kento Nagai, Tatsumi Sato, Chie Kojima (Graduate School of Engineering, Osaka Prefecture University)

P-050

Chemical stability of agonist peptides to neuromedin U receptor type 2
Yu Sasaki, Kentaro Takayama, Akihiro Taguchi, Atsuhiko Taniguchi, Yoshio Hayashi (Department ofMedicinal Chemistry, Tokyo University of Pharmacy and Life Sciences)

P-051

Quality control of disulfide-coupled folding of a peptide hormone, uroguanylin, on molecular evolution
Aman Lall Maharjan, Toi Osumi, Mayu Fukutsuji, Shigeru Shimamoto, Yuji Hidaka (Graduate School of
Science and Engineering Research, Kindai University)

P-052

Enzyme activation mechanism of cocoonase
Mai Takegawa1, TsubasaTagawa1, Ayumi Ogata1, Mitsuhiro Miyazawa2, Shigeru Shimamoto1, Yuji
Hidaka1 (1Graduate School of Science and Engineering Research, Kindai University, 2Institute ofAgrobiological Sciences, National Institute of Agriculture and Food Research Organization)

P-053

Cloning and functional analyses of digestive enzymes derived from Nephila clavata
Tsubasa Tagawa1, Teruki Hagiwara1, Mitsuhiro Miyazawa2, Shigeru Shimamoto1, Yuji Hidaka1(1Graduate School of Science and Engineering Research, Kindai University, 2Institute of Agrobiological
Sciences, National Institute of Agriculture and Food Research Organization)

P-054

Mechanism of the disulfide-coupled folding of a de novo designed prouroguanylin protein
Mayu Fukutsuji, Aman Lall Maharjan, Toi Osumi, Saya Nishihara, Shigeru Shimamoto, Yuji Hidaka(Graduate School of Science and Engineering Research, Kindai University)

P-055

Head-to-tail cyclic α-ABpeptoids: a new class of peptidomimetic foldamers
Eun-Kyoung Jee, Nakeun Ko, Hyunchul Kwon, Eunsung Lee, and Hyun-Suk Lim (Department ofChemistry and Division of Advanced Material Science, Pohang University of Science and Technology(POSTECH))

P-101–154: October 24 (Thursday) 17:15–18:45
P-101

Synthesis of peptide carriers to improve nucleic acid release activity(15)

Yuta Uematsu1, Masayuki Yamasaki2, Jun Hayashida3, Kin-ya Tomizaki1 (1Department of Materials
Chemistry, Ryukoku University, 2Department of Food Science and Human Nutrition, Ryukoku
University, 3Sogo Pharmaceutical Co.)
P-102

Synthesis of a novel collagen model peptide with carboxyl groups
Kisaki Nakamoto, Kin-ya Tomizaki (Department of Materials Chemistry, Ryukoku University)

P-103

Large-scale asymmetric synthesis of Fmoc-(S)-2-amino-6,6,6-trifluorohexanoic acidToshio Miwa1, Hiroki Moriwaki1, Hidenori Abe1, Zizhen Yin2, Jianlin Han2, Vadim A. Soloshonok3,4(1Hamari Chemicals Ltd, 2College of Chemical Engineering Nanjing Forestry University, 3Department ofOrganic Chemistry I, Faculty of Chemistry University of the Basque Country, UPV/EHU,
4

P-104

IKERBASQUE, Basque Foundation for Science)

Synthetic study of TIGIT protein for mirror-image screening
Naoya Iwamoto, Jumpei Sasaki, Keisuke Aoki, Shinsuke Inuki, Hiroaki Ohno, Shinya Oishi (Graduate
School of Pharmaceutical Sciences, Kyoto University)

P-105

Supramolecules of peptidomimetics with multiple boronates
Kota Miyata1, Ryota Fujisawa1, Airi Narita1, Makoto Roppongi2, Shingo Tamesue1, Satoshi Ito1, Toru
Oba1 (1Department of Material and Environmental Chemistry, Graduate School of Engineering,
Utsunomiya University, 2Advanced Instrumental Analysis Department, Center for Industry-University
Innovation Support, Utsunomiya University)

P-106

Synthesis and biological evaluation of S-octylsulfoniododecaborate containing L-amino acids for boron
neutron capture therapy
Yoshihide Hattori1, Miki Ishimura1, Youichirou Ohta1, Hiroshi Takenaka1, Kouichi Matsumoto2, Kouki
Uehara3, Tomoyuki Asano3, Mitsunori Kirihata1 (1Research Center of BNCT, Osaka Prefecture
University, 2Department of Chemistry, Faculty of Science and Engineering, Kindai University, 3Stella
Pharma Co.)

P-107

2H-Azirines as novel precursors of peptidomimetics
Toru Oba1, Yuka Yoshizawa1, Shintaro Anju1, Hiroto Takahashi1, Kota Miyata1, Shingo Tamesue1,
Satoshi Ito1, Makoto Roppongi2 (1Department of Material and Environmental Chemistry, Graduate
School of Engineering, Utsunomiya University, 2Advanced Instrumental Analysis Department, Center for
Industry-University Innovation Support, Utsunomiya University)

P-108

Stalobacin: discovery of a new class of lipopeptide antibiotic with potent antibacterial activity against
multidrug-resistant bacteria
Kouhei Matsui, Yukiko Kan, Junko Kikuchi, Keisuke Matsushima, Miki Takemura, Hideki Maki, Iori
Kozono, Taichi Ueda, Kazuyuki Minagawa (Pharmaceutical Research Center, Shionogi & Co., Ltd.)

P-109

Bioactive peptides from the turrid turris normandavidsonii
Abe Ernest Johann E. Isagan1, Oliver John V. Belleza2, Aaron Joseph L. Villaraza2, Gisela P.
Concepcion1 (1The Marine Science Institute, University of the Philippines, 2Institute of Chemistry,
University of the Philippines)

P-110

Enzymatic stability of myostatin inhibitory peptides
Miki Odagiri, Kentaro Takayama, Akihiro Taguchi, Atsuhiko Taniguchi, Yoshio Hayashi (Department ofMedicinal Chemistry, Tokyo University of Pharmacy and Life Sciences)(16)

P-111

Mitocryptide-2: investigation of its pathophysiological roles utilizing a specific neutralizing monoclonal
antibody
Yoshito Takamuro, Takenori Yamada, Hiroki Morikawa, Naoyuki Tamura, Tatsuya Hattori, Yoshiaki
Kiso, Hidehito Mukai (Laboratory of Peptide Science, Graduate School of Bio-Science, Nagahama
Institute of Bio-Science and Technology)

P-112

Enhanced cellular uptake of extracellular vesicles via macropinocytosis induction by modification ofcell-penetrating sC18 peptides on the vesicle membranes
Kosuke Noguchi1, Tomoka Takatani-Nakase2, Ines Neundorf3, Ikuhiko Nakase1 (1Graduate School of
Science, Osaka Prefecture University, 2School of Pharmacy and Pharmaceutical Sciences, Mukogawa
Women’s University, 3Institute of Biochemistry, Department of Chemistry, University of Cologne)

P-113

Artificially designed pH-responsive α helical peptides that damage tumor cells selectively
Haruka Sakurai1, Kanon Nishimura2, Shota Yamamoto2, Tatsuo Maruyama2, Atsuo Tamura1 (1Graduate
School of Science, Kobe University, 2Graduate School of Engineering, Kobe University)

P-114

Development of DNA photo-cross-linkable peptide containing 3-cyanovinylcarbazole amino acid
Zhiyong Qiu, Shigetaka Nakamura, Kenzo Fujimoto (School of Advanced Science and Technology,
Japan Advanced Institute of Science and Technology)

P-115

Translocation activity of cell-penetrating peptides possessing a hydrophobic acyl group
Mizuho Hatano, Tomohiro Miyatake (Department of Materials Chemistry, Ryukoku University)

P-116

Inhibition of tau amyloid formation using catalytic photo–oxygenation
Taka Sawazaki1, Takanobu Suzuki2, Yusuke Shimizu1, Yu Nemoto2, Atsuhiko Taniguchi1, Shuta Ozawa2,
Yukiko Hori2, Taisuke Tomita2, Youhei Sohma1, Motomu Kanai1 (1Laboratory of Synthetic Organic
Chemistry, Graduate School of Pharmaceutical Sciences, The University of Tokyo, 2Laboratory of
Neuropathology and Neuroscience, Graduate School of Pharmaceutical Sciences, The University ofTokyo)

P-117

Interaction with plasma membrane and curvature inducibility of branched oligomeric EpN18
Wei-Yuan Hsu, Takayuki Sakai, Toshihiro Masuda, Shiroh Futaki (Institute for Chemical Research,
Kyoto University)

P-118

In vitro selection of an alcohol dehydrogenase peptidic enzyme
Yamato Komatsu, Ryota Yokosuka, Yuki Goto, Hiroaki Suga (Graduate School of Science, The
University of Tokyo)

P-119

Loosening of lipid packing by recruitment of amphiphilic peptides onto cell surface
Takayuki Sakai, Kenichi Kawano, Miki Imanishi, Shiroh Futaki (Institute of Chemical Research, Kyoto
University)

P-120

Discovering protein-specific binders via tandem screening: combination of size exclusion
chromatography and extended phage display
Fumiko Hisamatsu, Masumi Taki (The Graduate School of Informatics and Engineering, Dept. ofEngineering Science, The University of Electro-Communications (UEC))

P-121

Screening of peptide ligands for Galectin-3 using a designed stapled α-helix peptide phage library
Teerapat Anananuchatkul, Takayuki Miki, Hiroshi Tsutsumi, Hisakazu Mihara (Department of Life
Science and Technology, School of Life Science and Technology, Tokyo Institute of Technology)(17)

P-122Development of a novel small molecule-binding peptide tag and its application to bioimaging
Mizuki Yamamoto1, Takehiro Ando1, Rina Iwamoto1, Keita Tsukamoto1, Takashi Kawakami1,2(1Department of Biotechnology, Faculty of Life and Environmental Sciences, University of Yamanashi,
2

P-123

JST, PRESTO)

Evaluation of the influence of amide-to-ester substitution on conformational preference of a cyclic
peptideYuki Hosono1, Jumpei Morimoto1, Shinsuke Sando1,2 (1Department of Chemistry and Biotechnology,
Graduate School of Engineering, The University of Tokyo, 2Department of Bioengineering, Graduate
School of Engineering, The University of Tokyo)

P-124

A fluorophore-conjugated phage library for screening of a peptide-based fluorescent biosensor for
Galectin-3
Masahiro Hashimoto, Takayuki Miki, Iou ven Chang, Hiroshi Tsutsumi, Hisakazu Mihara (School ofLife Science and Technology, Tokyo Institute of Technology)

P-125

Development of membrane permeable cyclic peptides as STAT3 dimerization inhibitors: a
conformational restriction strategy for regurating protein-protein interactions
Takayuki Osada1, Kouhei Matsui2, Katsumi Ota3, Koichi Fujiwara1, Akira Asai3, Mizuki Watanabe1,4,
Satoshi Shuto1 (1Faculty of Pharmaceutical Sciences, Hokkaido University, 2SHIONOGI & CO., LTD.,
3

P-126

Graduate School of Pharmaceutical Societies, University of Shizuoka, 4AMED)

Generation of de novo inhibotor of IKK-epsilon from a phage–displayed helix-loop-helix peptide
library tethering adenosine
Natsumi Nakajima, Kousuke Mihara, Daisuke Fujiwara, Ikuo Fujii (Department of Biological Science,
Graduate School of Science, Osaka Prefecture University)

P-127

Development of fluorescent pH probes toward fluorescence imaging of extracellular environments
using self-assembling peptides
Ren Aoki, Takayuki Miki, Hisakazu Mihara, Hiroshi Tsutsumi (School of Life Science and Technology,
Tokyo Institute of technology)

P-128

Improvement of phage binding ability to target proteins in combination with his-tag and Ni(II)complex interaction
Kenta Seko, Takayuki Miki, Teerapat Anananuchatkul, Hiroshi Tsutsumi, Hisakazu Mihara (School ofLife Science and Technology, Tokyo Institute of Technology)

P-129

Fluorescence turn-on histone probe for visualization of nucleosome dynamics
Takumi Ishii1, Gosuke Hayashi2, Akimitsu Okamoto1,3 (1Graduate School of Engineering, The Universityof Tokyo, 2Department of Biomolecular Engineering, Graduate School of Engineering, Nagoya
University, 3Research Center for Advanced Science and Technology, The University of Tokyo)

P-130

Chemical synthesis of intramolecular FRET histone protein visualizing H2A-H2B dimerization
Motoyuki Ogata1, Gosuke Hayashi2, Takuma Sueoka1, Daisuke Sakakibara1, Akimitsu Okamoto1,3(1Department of Chemistry and Biotechnology, Graduate School of Engineering, The University ofTokyo, 2Department of Biomolecular Engineering, Graduate School of Engineering, Nagoya University,
3

P-131

Research Center for Advanced Science and Technology, The University of Tokyo)

Construction of gene expression control system using photolabile PNA peptide binding to guanine-rich
DNA/RNA(18)

Shungo Sakashita1, Tamaki Endoh2, Arisa Okada1, Kenji Usui1 (1Faculty of Frontiers of Innovative
Research in Science and Technology (FIRST), Konan University, 2Frontier Institute for BiomolecularEngineering Research (FIBER), Konan University)
P-132

Studies on cell penetrating peptides containing 4-guanidino-L-proline residues
Kana Arai1, Mami Yasukagawa2, Mutsumi Sugo2, Akinori Yokoyama1, Yurie Kagawa1, Toshitada
Yoshihara3, Seiji Tobita3, Keiichi Yamada3 (1Department of Chemistry and Chemical Biology, Gunma
University, 2Materials and Bioscience Program, Graduate School of Science and Technology, Gunma
University, 3Division of Molecular Science, Gunma University)

P-133

Creation of enveloped artificial viral capsid by electrostatic interaction between β-annulus peptide andlipid
Hiroto Furukawa1, Hiroshi Inaba1, Yoshihiro Sasaki2, Kazunari Akiyoshi2, Kazunori Matsuura1(1Graduate School of Engineering, Tottori University, 2Graduate School of Engineering, Kyoto
University)

P-134

Multimeric amphipathic cell penetrating peptides and applications using pH-sensitive self-cleaving
linkers
Sejong Choi, Jae Hoon Oh, Seung-Eun Chong, Joon Hyung Ahn, Yan Lee (Department of Chemistry,Seoul National University)

P-135

Construction of artificial viral capsid decorated with green fluorescent protein on the surface
Kazuki Shimomura1, Hiroshi Inaba1, Takashi Iwasaki2, Kazunori Matsuura1 (1Graduate School ofEngineering, Tottori University, 2Faculty of Agriculture, Tottori University)

P-136

Quantitative analysis of formation of artificial viral capsids using fluorescence correlation spectroscopy
Risako Kobayashi, Hiroshi Inaba, Kazunori Matsuura (Graduate School of Engineering, Tottori
University)

P-137

Deformation of bilayer lipid membrane induced by transmembrane peptides
Kayano Izumi, Keisuke Shimizu, Ryuji Kawano (Department of Biotechnology and Life science, Tokyo
University of Agriculture and Technology)

P-138

Construction of visible light responsive nanocatalyst by mineralization using designed peptide
Makoto Ozaki1, Takaaki Tsuruoka1, Takahito Imai2, Kin-ya Tomizaki2, Kenji Usui1 (1Faculty of Frontiersof Innovative Research in Science and Technology (FIRST), Konan University, 2Department of Materials
Chemistry, Ryukoku University)

P-139

Self-assembling peptide materials functionalized with bioactive sequences for three dimensional MCF-7
cell culture
Jyh Yea Chia, Takayuki Miki, Hisakazu Mihara, Hiroshi Tsutsumi (School of Life Science andTechnology, Tokyo Institute of Technology)

P-140

Electrophysiological observation of direct membrane penetration on cell penetrating peptides
Chihiro Saito, Yuri Numaguchi, Keisuke Shimizu, Ryuji Kawano (Department of Life Science andBiotechnology, Tokyo University of Agriculture and Technology)

P-141

Development of metal ion-responsive self-assembling peptides with a urea bondJumpei Shiota, Takayuki Miki, Hisakazu Mihara, Hiroshi Tsutsumi (School of Life Science andTechnology, Tokyo Institute of Technology)

P-142

Development of liposome-like nanostructures composed of short amphiphilic elastin-like peptides(19)

Naoki Sakamoto1, Daiki Tatsubo1, Keiji Sato1, Keisuke Tomohara2, Keitaro Suyama2, Iori Maeda3,
Takeru Nose1,2 (1Department of Chemistry, Faculty and Graduate School of Science, Kyushu University,
2

Faculty of Arts and Science, Kyushu University, 3Department of Physics and Information Technology,

Kyushu Institute of Technology)
P-143

Oligopeptide desing and synthesis for enamel remineralization
Enrique Ezra Zuñiga Heredia1, Fernando Arteaga Arteaga2,3, Masahiro Iijima1, Masaya Sawamura2(1Division of Orthodontics and Dentofacial Orthopedics, Department Oral Growth and Development,
School of Dentistry, Health Sciences University of Hokkaido, 2School of Science, Hokkaido University,
3

P-144

Institute for the Advancement of Higher Education, Hokkaido University)

Structure activity relationship study of an α-dystroglycan binding peptide from the laminin α2 chain
LG4-5 modules
Keisuke Hamada, Guangrui Zhang, Yuji Yamada, Yamato Kikkawa, Motoyoshi Nomizu (Department ofClinical Biochemistry, School of Pharmacy, Tokyo University of Pharmacy and Life Sciences)P-145

Identification of α-dystroglycan binding sequences in the laminin α2 chain LG4-5 modules
Guangrui Zhang, Keisuke Hamada, Yuji Yamada, Yamato Kikkawa, Motoyoshi Nomizu (Department ofClinical Biochemistry, School of Pharmacy, Tokyo University of Pharmacy and Life Sciences)

P-146

Development of cell culture substrate generated by trypsin digestion of Aβ fibrils
Shin-ichiro Yokota1, Yasumasa Mashimo2, Yoshio Hamada1, Youji Harada3, Masayasu Mie2, Eiry
Kobatake2, Kenji Usui1 (1Faculty of Frontiers of Innovative Research in Science and Technology(FIRST), Konan University, 2Department of Life Science and Technology, School of Life Science andTechnology, Tokyo Institute of Technology, 3Clean Chemical Co., Ltd)

P-147

Propulsion of oil-in-water droplets driven by light-induced peptide nanofiber growth
Kenji Hatta, Hiroshi Inaba, Kazunori Matsuura (Graduate School of Engineering, Tottori University)

P-148

A design strategy for beta-peptoids with constraint on multiple backbone dihedral angles
Jungyeon Kim1, Jumpei Morimoto1, Shinsuke Sando1,2 (1Department of Chemistry and Biotechnology,
School of Engineering, The University of Tokyo, 2Department of Bioengineering, School of Engineering,
The University of Tokyo)

P-149

Control of assembled structures of viral coat proteins at emulsion interfaces
Michihiro Tanaka1, Toshiki Sawada1,2, Takeshi Serizawa1 (1School of Materials and Chemical
Technology, Tokyo Institute of Technology,2

Precursory Research for Embryonic Science andTechnology (PRESTO), Japan Science and Technology Agency (JST))
P-150

Evaluation of physiological activity of elastin peptide derived from tuna arterial sphere against normal
human fibroblasts (NHDF)
Otome Kitano1,2, Kohji Nakazawa2, Yasushi Nakamura1, Shinsuke Shiratuchi2 (1Shinryo Corporation,
2

P-151

Department of Life and Environment Engineering, The University of Kitakyushu)

Development of fluorine-containing cell-penetrating peptide
Toshiki Mikami1, Kosuke Aikawa1, Jumpei Morimoto1, Shinsuke Sando1,2, Kyoko Nozaki1, Takashi
Okazoe3 (1Department of Chemistry & Biology, School of Engineering, The University of Tokyo,
2

Department of Bioengineering, School of Engineering, The University of Tokyo, 3Materials Integration

Laboratories, AGC Inc.)(20)

P-152

Identification of new associating proteins of PPM1 phosphatase ILKAP
Nanase Tsukahara, Natsumi Nakagawa, Shogo Ito, Rui Kamada, Kazuyasu Sakaguchi (Laboratory of
Biological Chemistry, Department of Chemistry, Faculty of Science, Hokkaido University)

P-153

Antibacterial activity of lactoferricin B like peptide: Reactive oxygen species-induced apoptosis-likedeath in Escherichia coli
Suhyun Kim, Dong Gun Lee (School of Life Sciences, BK 21 Plus KNU Creative BioResearch Group,
College of Natural Sciences, Kyungpook National University)

P-154

Evaluation of cell-penetrating ability of bicyclic peptoids
Hee Myeong Wang, Chang Deok Seo, Hyun-Suk Lim (Department of Chemistry and Division ofAdvanced Material Science, Pohang University of Science and Technology (POSTECH))

P-201–253: October 25 (Friday) 12:50–14:20
P-201

Combining tandem mass spectrometry and high-throughput peptide synthesis for high-confidence
neuropeptidomics
Chihiro Kawano, Eisuke Hayakawa, Hiroshi Watanabe (Evolutionary Neurobiology Unit, Okinawa
Institute of Science and Technology)

P-202

Synthesis of hydrophobic peptides/proteins using solubilizing trityl tag
Shugo Tsuda, Shun Masuda, Taku Yoshiya (Peptide Institute, Inc.)

P-203

Chemical synthesis of ubiquitinated histone H3 and its effect on dna methyltrasferase 1
Toru Kawakami1, Yuichi Mishima1, Masaya Takazawa1, Hironobu Hojo1, Isao Suetake1,2 (1Institute forProtein Research, Osaka University, 2College of Nutrition, Koshien University)

P-204

Efficient methods for rapid development of therapeutic peptides with higher structural complexity
Cyf Ramos-Colon1, Takanori Ikegami2, Daniel Martinez1, Andrew Kennedy1, James Cain1 (1Gyros
Protein Technologies, 2ASTECH CORPRATION)

P-205

Peptide secondary structural change in response to reductive milieu
Yuriko Otani1, Hikaru Nonaka1, Mitsunobu Doi2, Makoto Oba1, Masakazu Tanaka1 (1Graduate School of
Biomedical Sciences, Nagasaki University, 2Osaka University of Pharmaceutical Sciences)

P-206

OFF-to-ON Control of trypsin activity and target protein degradation using ISAAC
Koushi Hidaka1,2, Keiko Hojo1,2, Yuko Tsuda1,2 (1Faculty of Pharmaceutical Sciences, Kobe Gakuin
University, 2Cooperative Research Center for Life Science, Kobe Gakuin University)

P-207

Design of the plasmin inhibitor having the imidazole scaffold
Yuko Tsuda1,2, Koushi Hidaka1,2, Keiko Hojo1,2, Keigo Gohda3, Naoki Teno4, Keiko Wanaka5 (1Facultyof Pharmaceutical Sciences, Kobe Gakuin University, 2Cooperative Research Center for Life Science,
Kobe Gakuin University, 3Computer-Aided Molecular Modeling Research Center Kansai, 4Faculty ofClinical Nutrition,

Hiroshima International University,

5

Research Projects on Thrombosis andHaemostasis)
P-208

Crystal structure of gramicidin S hydrochloride

P-209

Replica-exchange Monte Carlo SAAP simulation for molecular assembly of silk fibroin model peptides

Mitunobu Doi, Akiko Asano (Osaka University of Pharmaceutical Sciences)
Michio Iwaoka1, Koji Yoshida1, Hisayuki Morii2, Akira Takahashi2, Atsushi Kameyama2 (1Departmentof Chemistry, Tokai University, 2Department of Chemistry, Kanagawa University)(21)

P-210Infrared analyses on amyloid-forming oligopeptides of alanine
Hisayuki Morii, Masayuki Nara (Department of Chemistry, College of Liberal Arts and Sciences, Tokyo
Medical and Dental University)

P-211

Design and synthesis of relaxin family peptide-2 stapled analogue
Testuya Fukumoto1, Keiko Hojo1,2, Koushi Hidaka1,2, Katsutoshi Yayama1,2, Yuko Tsuda1,2 (1Faculty of
Pharmaceutical Sciences, Kobe Gakuin University, 2Cooperative Research Center for Life Science, Kobe
Gakuin University)

P-212

Investigation of antibacterial activity of short linear or cyclic derivatives of myticalin A6
Keiko Okimura1, Keiko Matsubara1, Rie Suzuki1, Hanako Ito1, Ayumi Sato1, Kaori Sugimoto2 (1Facultyof Pharmaceutical Sciences, Hokuriku University, 2SCRUM Inc.)

P-213

Structure-based design of hetero-bivalent peptides to inhibit human vascular endothelial growth factorA
Masataka Michigami, Ikuo Fujii (Department of Biological Science, Osaka Prefecture University)

P-214

Conserved tyrosine residues involve in the orientation of the transmembrane region in FGFR3
Hiroko Tamagaki-Asahina, Takeshi Sato (Kyoto Pharmaceutical University)

P-215

A series of qunine prodrugs for an anti-malarial treatment
Yoshio Hamada, Kenji Usui (Faculty of Frontiers of Innovative Research in Science and Technology(FIRST), Konan University)

P-216

Discovery of antibody light chains possessing tau protein-hydrolyzing activity
Hiroaki Taguchi1, Yuki Kato1, Taminao Ito1, Emi Hifumi2, Taizo Uda3,4 (1Faculty of Pharmaceuticals
Sciences, Suzuka University of Medical Science, 2Research Promotion Institute, Oita University, 3Facultyof Engineering, Oita University, 4Institute of Systems, Information Technologies and Nanotechnologies)

P-217

Facile synthesis of Fmoc-aminoacyl-N-alkylcysteine dipeptide by Ugi multi-component reaction
Yuya Asahina, Hironobu Hojo (Institute for Protein Research, Osaka University)

P-218

A study toward endowing PPI inhibition activity to membrane-permeabilizing peptides
Yuki Nagano, Misao Akishiba, Shiroh Futaki (Institute for Chemical Research, Kyoto University)

P-219

Mitochondria-targeting drug delivery by peptide carriers
Rio Kawamura1, Yuta Uematsu1, Masayuki Yamasaki2, Kin-ya Tomizaki1 (1Department of Materials
Chemistry, Ryukoku University, 2Department of Food Science and Human Nutrition, Ryukoku
University)

P-220

Development of novel peptides useful for promoting growth and undifferentiation of induced
pluripotent stem cells
Masashi Sato1, Yoshitsugu Ohnuki1, Shinji Masui1,2, Takashi Kawakami1,3, Hiroshi Kurosawa1(1Department of Biotechnology, Faculty of Life and Environmental Sciences, University of Yamanashi,
2

P-221

Advanced Biotechnology Center, University of Yamanashi, 3JST, PRESTO)

Development of cell-permeable anti-HIV peptides based on capsid proteins
Rongyi Wang1, Takuya Kobayakawa1, Moemi Kaneko1, Kofi Owusu1, Tsutomu Murakami2, Hirokazu
Tamamura1 (1Institute of Biomaterials and Bioengineering, Tokyo Medical and Dental University, 2AIDS
Research Center, National Institute of Infectious Diseases)

P-222

Directed evolution of a novel PCSK9-binding peptide for hypercholesterolemia treatment
Takehiro Ando1, Takumi Yokoyama1, Mizuki Yamamoto1, Takashi Kawakami1,2 (1Department of
Biotechnology, Faculty of Life and Environmental Sciences, University of Yamanashi, 2JST, PRESTO)(22)

P-223

Assessment of the intracellular cargo delivery efficiency by conjugation with L17E analogues
Kenta Shinga, Misao Akishiba, Kentarou Sakamoto, Shiroh Futaki (Institute of Chemical Research,
Kyoto University)

P-224

Improving the activity of L17E by endowing pH-sensitive membrane destabilizing activity
Kentarou Sakamoto, Misao Akishiba, Takahiro Iwata, Kenichi Kawano, Shiroh Futaki (Institute for
Chemical Research, Kyoto University)

P-225

Mitocryptides: investigation of signaling mechanisms induced by novel neutrophil-activating peptides
derived from mitochondrial transit signal sequences
Takayuki Marutani, Koji Ohura, Shinichiro Tamura, Kenta Nakashima, Hiroki Morikawa, Tatsuya
Hattori, Yoshiaki Kiso, Hidehito Mukai (Laboratory of Peptide Science, Graduate School of Bio-Science,
Nagahama Institute of Bio-Science and Technology)

P-226

Evaluation of applicability of peptide self-cleavage reaction at canaline
Shugo Tsuda, Shun Masuda, Taku Yoshiya (Peptide Institute, Inc.)

P-227

Development of a nanoBRET-based sensitive screening method to search for chemokine receptor
CXCR4 ligands
Maxwell M. Sakyiamah, Wataru Nomura, Takuya Kobayakawa, Hirokazu Tamamura (Institute of
Biomaterials and Bioengineering, Tokyo Medical and Dental University)

P-228

Relationship between membrane remodeling ability and endocytosis

P-229

Auto-ubiquitination of artificial ring fingers in human breast cancer cells

Toshihiro Masuda, Shiroh Futaki (Institute for Chemical Research, Kyoto University)
Kazuhide Miyamoto, Arisa Nakatani, Yukari Taguchi, Kazuki Saito (Pharmaceutical Sciences, Himeji
Dokkyo University)
P-230

Synthesis and evaluation of α-gal antibody conjugate for new cancer immune therapy by recruiting
natural antibodies
Yoshiyuki Manabe1,2, Julinton Sianturi1, Kento Tokunaga1, Kazuya Kabayama1,2, Koichi Fukase1,2(1Graduate School of Science, Osaka University, 2Project Research Center for Fundamental Sciences,
Osaka University)

P-231

Cell-penetrating activity analysis of amphiphilic α-helix peptides from designed peptide library
Mimi Tian, Takayuki Miki, Hiroshi Tsutsumi, Hisakazu Mihara (School of Life Science and Technology,
Tokyo Institute of Technology)

P-232

Development of a small anti-HER2 antibody mimetic by double-CDR grafting
Kyra See, Tetsuya Kadonosono, Wanaporn Yimchuen, Shinae Kizaka-Kondoh (School of Life Scienceand Technology, Tokyo Institute of Technology)

P-233

Cell permeability evaluation of helical cell penetrating peptides using cyclic disubstituted amino acids
having basic functional groups
Takuma Kato1, Jun Yasukiyo1, Yuki Kita1, Kazuki Iwanari1, Akiko Asano1, Makoto Oba2, Masakazu
Tanaka2, Mitsunobu Doi1 (1Osaka University of Pharmaceutical Sciences, 2Graduate School of
Biomedical Sciences, Nagasaki University)

P-234

Transcytosis of histidine-rich peptide derived from Helicobacter pylori in gastric epithelial cells
Yurika Inui, Tsuyoshi Kawano, Takashi Iwasaki (Faculty of Agriculture, Tottori University)(23)

P-235

Evaluation of intracellular delivery efficiency of L17E dimers
Yohei Nomura, Misao Akishiba, Kentarou Sakamoto, Shiroh Futaki (Institute for Chemical Research,
Kyoto University)

P-236

Detection of ligand-protein interactions using a combination of ligation and reporter enzyme
reconstitution
Tsuyoshi Takahashi, Hiroaki Hagiwara (Graduate School of Science and Technology, Gunma
University)

P-237

Dimerization of plexin B1 binding macrocyclic peptides and its evauation
Masanobu Nagano1, Nasir Kato Bashiruddin1, Yukiko Matsunaga2, Junichi Takagi2, Hiroaki Suga1(1Department of Chemistry, Graduate School of Science, The University of Tokyo, 2Laboratory ofProtein Synthesis and Expression, Institute for Protein Research, Osaka University)

P-238

Fluorogenic ZIP tag-probe system for fluorescent imaging of endogenous protein expression
Wataru Nomura1,2, Takumi Kamimura2, Takuya Kobayakawa2, Hirokazu Tamamura2 (1Graduate Schoolof Biomedical and Health Sciences, Hiroshima University, 2Institute of Biomaterials and Bioengineering,Tokyo Medical and Dental University)

P-239

Pathogenic fibril growth at a target area by novel force-induced nanolithography of amyloid β
Ryu Tashiro1, Hiroaki Taguchi1, Kumi Hidaka2, Masayuki Endo2, Hiroshi Sugiyama2,3 (1Faculty of
Pharmaceutical Sciences, Suzuka University of Medical Sciences, 2Department of Chemistry, Graduate
School of Science, Kyoto University, 3Institute for Integrated Cell-Material Sciences (iCeMS), Kyoto
University)

P-240

Design of barnacle-mimetic peptides enhanced RGDS cell attachment site for tissue engineeringscaffold
Yoshiaki Hirano1,2, Daisuke Fujii1, Ami Takagi1, Sachiro Kakinoki1,2, Kei Kamino3 (1Faculty ofChemistry, Materials and Bioengineering, Kansai University,

2

Organization for Research andDevelopment of Innovative Science and Technology, Kansai University,

3

National Institute ofTechnology and Evaluation)
P-241

Three-dimensional cell culture using laminin peptide-conjugated agarose hydrogels
Yuji Yamada, Chihiro Yoshida, Keisuke Hamada, Yamato Kikkawa, Motoyoshi Nomizu (School of
Pharmacy, Tokyo University of Pharmacy and Life Sciences)P-242

Stability of Phe-containing elastin-like peptides against proteases in digestive organs
Iori Maeda1, Miki Kawakami1, Suguru Taniguchi1, Keitaro Suyama2, Takeru Nose2 (1Department of
Physics and Information Technology, Kyushu Institute of Technology, 2Faculty of Arts and Science,
Kyushu University)

P-243

Development of peptide immobilized nano-spheres and detection of antibodies to Japanese encephalitis
virus in the wild boars in Gunma prefecture, Japan
Hotaka Shibao1, Daichi Nakayama1, Minoru Yamaji1, Yuko Oku2, Hiroyuki Oku1 (1Division of
Molecular Science, Graduate School of Science & Engineering, Gunma University, 2Center of Regional
Medical Research and Education, Gunma University Hospital)(24)

P-244Development of chitosan/dicarboxylic acid hydrogel with cell adhesive peptides as cell culture matrix
Kentaro Hozumi1,2, Chie Takahashi1, Hayato Yamada2, Ayano Kobayashi1, Rui Hiraga1, Chihiro
Uchiyama2, Yoshio Hayashi2, Motoyoshi Nomizu2 (1Department of Applied Clinical Dietetics, Kitasato
Junior College of Health and Hygienic Science, 2School of Pharmacy, Tokyo University of Pharmacy andLife Sciences)P-245

Laser dissolution of fibrous peptide at terahertz region
Takayasu Kawasaki1, Koichi Tsukiyama1, Akinori Irizawa2 (1IR FEL Research Center, Tokyo Universityof Science, 2The Institute of Scientific and Industrial Research, Osaka University)

P-246

Practice of automated method development and automated robustness test of synthetic peptides by AI
Masaaki Suzuki1, Daisuke Kubo2, Kosuke Suzuki2, Yuko Aoki1, Shigenori Sonoki1 (1Chromsword Japan
Co., Ltd., 2Jitsubo CO.,LTD.)

P-247

Research for evaluation of the interaction between synthetic co-factor-derived peptide and vitamin D
receptor
Nami Ohashi, Shiori Nagata, Mami Yoshizawa, Toshimasa Itoh, Keiko Yamamoto (Laboratory of Drug
Design and Medicinal Chemistry, Showa Pharmaceutical University)

P-248

Evaluation of cysteic acid in bleached hair using soft X-ray spectroscopy
Kazuyuki Suzuta, Kosuke Watanabe, Takaaki Maeda, Sho Kobayashi, Len Ito (Development
Headquarters, Milbon Co. Ltd.)

P-249

An approach toward visual detection of single nucleotide polymorphism using pseudocomplementary
peptide nucleic acidShun-suke Moriya1, Yuko Sasa1, Keiko Kuwata2, Yasutada Imamura3, Yosuke Demizu4, Masaai
Kurihara5, Atsushi Kittaka1, Toru Sugiyama1 (1Faculty of Pharma-Sciences, Teikyo University, 2Instituteof Transformative Bio-Molecules (WPI-ITbM), Nagoya University, 3School of Advanced Engineering,
Kogakuin University,
5

P-250

4

Division of Organic Chemistry, National Institute of Health Sciences,

Department of Pharmaceutical Sciences, International University of Health and Welfare)A chromophore-immobilized peptide binding assay for assessing skin sensitization in vitro
Kenji Usui1, Hiroshi Miyazaki2, Hikaru Takaishi1, Hidefumi Ikeda3, Yoshio Hamada1, Kunihiko
Yamashita2 (1Faculty of Frontiers of Innovative Research in Science and Technology (FIRST), Konan
University, 2Daicel Corporation, 3Mandom Corporation)

P-251

Solvation-directed formation pathways for peptide nanotubes
Avanashiappan Nandakumar1, Motoki Ueda1,2, Yoshihiro Ito1,2 (1Emergent Bioengineering Materials
Research Team, RIKEN Center for Emergent Matter Science, 2Nano Medical Engineering Laboratory,
RIKEN)

P-252

Proposal of Efficient Peptide Synthesis workflow
Fumio Kumakura1, Cedric Rentier2 (1Peptides Application Engineer, Japan, Biotage Japan Ltd., 2Peptides
and Biomolecules Application Specialist, Asia Pacific, Biotage Japan Ltd.)P-253

In vitro selection of anti-gliadin VHH and its application for immuno-PCR using cDNA display
Chathuni Jayathlake1, Shigefumi Kumachi2, Hidenao Arai2, Maiko Motohashi2, Akikazu Murakami3,
Naoto Nemoto1,2 (1Graduate School of Science and Engineering, Saitama University, 2Epsilon MolecularEngineering, Inc., 3Graduate School of Medicine, University of the Ryukyus)(25)