Immunotoxicology Specialty
Section Newsletter
Fall/Winter 2016 edition
2016-2017
Executive Committee
President
L. Peyton Myers
Vice President
Victor J. Johnson
Vice President-Elect
Jamie DeWitt
Secretary/Treasurer
Kristen A. Mitchell
Past President
Rafael A. Ponce
Senior Councilor
Haley Neff-LaFord
Junior Councilor
Rodney Prell
Postdoc Representative
Angela Groves
Student Representative
Jiajun (Brian) Zhou
The ImTox SS Newsletteris published 3 times/year(Summer, Fall, and Winter). If
you would like to share an itemof interest with members of the
ImTox SS, please send it to theCommunications Committee
Co-Chairs. All comments on, or
suggestions to the newsletterare welcome.
Jiajun (Brian) Zhou
zhoujiaj@msu.edu
Angela Groves
Angela_Groves@URMC.
Rochester.edu
Kristen A. Mitchell
kristenmitchell@boisestate.edu
Immunotoxicology Specialty Section

President’s Message

Greetings, ITSS members and Happy Holidays!
It is hard to believe but the SOT Annual Meeting is only a
few months away. I hope that your Holidays are going well. As weclose out 2016, don’t forget that we have several deadlines andopportunities within the coming weeks.
First off, we have deadlines for both awards and program
fast approaching. Awards are always a large part of our annual
meeting and will highlight successes of our members. Pleasebe sure to nominate your colleagues for recognition for theiraccomplishments. The details for all awards, requirements fornominees, and submission, associated deadlines, and primarycontacts are provided on the ITSS website, so please visit (http://
www.toxicology.org/groups/ss/imtox/deadlines.asp).
Next, it is never too early to be considering the program for the
next SOT Annual Meeting. While the SOT Program for 2017 in
Baltimore is finalized, the deadline for submission of the 2018
SOT program is in May 2017, only a few short weeks after the
SOT Annual Meeting. Please contact Jamie DeWitt, ITSS VP
Elect and 2018 Program Chair (DEWITTJ@ecu.edu), with yourinnovative, novel, and timely session ideas. ITSS members havebeen amazing contributors to the overall SOT program and wehope to continue that tradition. We look forward to discussing yourideas for sessions that will be both scientifically impactful andimportant for the ITSS membership as well as broadly interesting
to the general SOT membership. We would especially like to see
continuing education submissions from our ITSS members!
In this edition
President’s Message....................................................................1
Student & Postdoc article.............................................................2
Award Nomination.........................................................................3
JSIT Contribution Article...............................................................4
Program Committee Update.........................................................5
Member Spotlight..........................................................................6
Job Opportunities..........................................................................7
Exciting News...............................................................................7
Recent Publications......................................................................8
Fall 20161

President’s
MessageContinued

Next, we would like to thank our international
colleagues for continuing our partnerships. We arehoping to revitalize the International Committee in
ITSS to better enhance partnerships across evenmore countries. I would like to personally thank theJapanese Society of Immunotoxicology as well as
our EU partners who have worked with ITSS for
many years. We also hope that we can collaborate
with other groups in the future to further increaseinternational scientific exchange and collaborationin immunotoxicology. The continued goal of theInternational Committee is to better address mutual
needs and enhance collaborations.
As I mentioned in the last newsletter, wehave a training opportunity for ITSS members in the
Spring of 2017. We would like to thank ILSI/HESI
Immunotoxicology Technical Committee for thecontinued support for Immunotoxicology training.
The ILSI/HESI ITC is taking the reins on organizing
an outside Immunotoxicology session annually.
The inaugural meeting is tentatively planned forApril 18 and 19 in Gaithersburg, MD. ILSI/HESI ITC
will have more information about that opportunity inthe near future.
Lastly, don’t forget that we have elections forseveral ITSS Officer positions that will be on theballot for the 2017-2018 term. Please watch youremail for ballot information from SOT and be sureto participate and vote for your favorite candidate.
As always, please let us know if you havefeedback – we would love to hear your ideas
for ensuring we remain a robust and energized
specialty section. I look forward to seeing you in
Baltimore!

Student &Postdoc
ReportAs the end of the year approaches, I hopethat you all have a great holiday and are excited
for the 56th SOT Annual Meeting in Baltimore,
Maryland. There are many opportunities for students
and postdocs to get involved, including Chat withan Expert, Poster Tours, the Student/Postdoctoral
Scholar Mixer, ITSS Networking Event and the Tox
Showdown.
At the 56th SOT Annual Meeting, the ITSS
will host the Networking/Mentor event for students
and postdocs to have discussion with a panel ofprofessionals with various areas of expertise on(more details to be announced soon). The eventfrom last year was a great success. Students andpostdocs valued the interaction they had with thementors. Therefore, be on the lookout for more
information for the Networking/ mentor event.
The deadline for award nominations isquickly approaching. Awards available to students
and postdoctoral ITSS members include:• Best Presentation by a Student• Best Presentation by a Postdoctoral Trainee• Best Paper of the Year
Many travel awards are also available
through the specialty section and through SOT;
please check out the website for more details.
Lastly, we would like to remind everyone to
make sure their SOT member information is current
and correct so you do not miss email reminders
for the numerous events and activities available
to students and postdocs. If you would like to get
involved in event planning, or any of the ITSS
committees, please contact Jiajun (Brian) Zhou
(zhoujiaj@msu.edu) or Angela Groves (Angela_
Groves@URMC.Rochester.edu).
Jiajun (Brian) Zhou
Angela Groves, Ph.D.

L. Peyton Myers, Ph.D.
President, ITSS (2016-2017)
Immunotoxicology Specialty Section

Fall 2016

2

AwardNominations

Outstanding Young Immunotoxicologist Award
This award will be presented to a young
investigator with 10 years of less of experiencesince obtaining the highest degree and whose
work has made significant contributions to the fieldof immunotoxicology. Please submit nominations
to Victor Johnson (vjohnson@brt-labs.com) by
January 15, 2017.
Best Paper of the Year Award
Authors of the paper deemed to be the best paper
in immunotoxicology will receive this award. The
paper must have been published between January
1 and December 31 of the previous calendar year
and the first publication date (paper or e-version)
will be considered the publication date. Immunotoxicology papers published in any peer-reviewed
journal are acceptable. Please submit nominations
to Haley Neff-LaFord (hnlaFord@seagen.com) by
January 15, 2017.
Best Presentation by a Postdoctoral TraineeAward
Postdoctoral trainees who are presenting (posteror platform) at the 2017 SOT Annual Meeting are
eligible for this award. Nominees are asked tosubmit a written version of an immunotoxicology
presentation to be made at the Annual Meeting anda letter of nomination from the trainee’s advisor.
Please submit materials to Haley Neff-LaFord
Haley Neff-LaFord, Awards Committee Chair(hnlaFord@seagen.com) by January 15, 2017.
Best Presentation by a Student Award
Vos Lifetime Career Achievement Award in Students who are presenting (poster or platform) at
Immunotoxicology
the 2017 SOT Annual Meeting are eligible for thisThis award was named for the late Professor award. Nominees are asked to submit a written
Jeff Vos and will be presented to a senior investigator version of an immunotoxicology presentation towhose body of work represents an outstanding be made at the Annual Meeting and a letter ofcareer in immunotoxicology. Please submit nomination from the student’s advisor. Pleasenominations to Peyton Myers (Laine.Myers@fda. submit materials to Haley Neff-LaFord (hnlaFord@
hhs.gov) by January 15, 2017.
seagen.com) by January 15, 2017.
Outstanding Senior Immunotoxicologist Award HESI Immunotoxicology Young Investigator
This award will be presented to a senior Travel Award
investigator with more than 10 years of experience ILSI HESI sponsors this award to assist young
since obtaining the highest degree and whose investigators (<5 years since completing a graduate
work has made significant contributions to the field dissertation) in attending SOT and presenting theirof immunotoxicology. Please submit nominations research. Both U.S. and international investigators
to Victor Johnson (vjohnson@brt-labs.com) by are encouraged to apply. Please submit nominations
January 15, 2017.
to Peyton Myers (Laine.Myers@fda.hhs.gov) by
January 15, 2017. 					Immunotoxicology Specialty Section
Fall 2016
3
Did
you
read
an
outstanding
immunotoxicology paper this year? Read apresentation abstract that was amazing? Work withsomeone who you think embodies excellence in thefield of immunotoxicology? If you answered yes toany of these questions, then I urge you to nominate
the author, the presenter, or the colleague for anaward from the Immunotoxicology Specialty Section(ITSS). Recognizing these important contributionsof ITSS students, postdoctoral scientists, andcolleagues is one of the most important undertakingsof our specialty section. Additionally, acknowledging
the excellence of the scientists within ITSS helps todemonstrate how our science furthers the missionof SOT.
Please make it difficult for the Awards
Committee to choose recipients for these awards!
Nominate a student, postdoctoral scientist, or
colleague for one of the Immunotoxicology Specialty
Section Awards. You also may nominate yourself!
Descriptions of awards, Awards Committee contacts,and due dates are listed below. For a more detailed
description of the awards and their nomination
criteria, please visit the Immunotoxicology Specialty
Section web site:
http://www.toxicology.org/groups/ss/imtox/
deadlines.asp

JSIT
Contribution
ArticleIntroduction of the Japanese Society of
Immunotoxicology and collaboration with SOT
Immunotoxicology Specialty Section
I attended the 1991 annual meeting of theInternational Society for Immunopharmacology
at Tampa, Florida. It was a chance to meet key
individuals for a collaboration between JSIT
(Japanese Society of Immunotoxicology) and SOTIMTox-SS (Immunotoxicology Specialty Section).
At the time I was thinking of studying abroad
within NIEHS (National Institute of Environmental
Health Science, NIH) and visited Dr. Michael I.
Luster’s laboratory to observe the institute andsee the Research Triangle Park before attending
the conference. At Tampa, I met Dr. Jack H. Dean
(as well as Dr. Albert E. Munson and Dr. Joseph.
G. Vos, although my memory is a bit hazy) from
SOT, while Dr. Motoyasu Ohsawa, Dr. Yasuhide
Kouchi and I represented JSIT. We talked about afuture collaboration between both groups in Japanand the USA. I worked at Dr. Luster’s laboratory in
NIEHS from 1992 to 1993. The period of Dr. Fujio
Kayama’s work in the laboratory overlapped mine,and Dr. Kouchi had worked before me. Dr. Sei-ichiro
Hirano was working at Dr. Maryjane K. Selgrade’slaboratory when I visited the Research Triangle Parkin 1991. We had the opportunity to attend the SOTAnnual Meeting while in the USA. We also attended
the IMTox-SS meeting and extended our friendshipwith scientists from all around the world who were
working in the same field of immunotoxicology.
I returned to Japan in June of 1993 andcontinued my research on the immunotoxicology ofenvironmental toxicants such as metals. My main
target is arsenic and this research continues tothe present day. I presented my research findings
at Japanese scientific conferences that included
the “Society of Toxicological Science”, “Society ofHygiene,” and “Society of Occupational Health andPreventive Medicine.” However, since the numberof researchers in the field of immunotoxicology inJapan is small, discussion at these sessions was
not very active. It was within this background that
Immunotoxicology Specialty Section

Japanese scientists interested in immunotoxicology
started to prepare an immunotoxicology study
group with the initiative of Dr. Ohsawa. The study
group for immunotoxicology was then established inJune of 1994 with Dr. Yukio Kuroiwa as President.
Dr. Kayama and I then attended the SOT Annual
Meeting in Baltimore, Maryland in March of 1995,
and Dr. Kayama introduced the foundation of JSITat the IMTox-SS meeting. The 2nd annual meeting
was held on September 29, 1995 in Tokyo. Dr.
Luster was invited as a foreign speaker and lectured
on “Immunotoxicological evaluation of chemicals
and therapeutics: an update perspective.” The12th annual meeting during September 20–21,
2005 provided the opportunity to strengthen thecollaborative exchange between JSIT and SOT
IMTox-SS, and Dr. Mitchell D. Cohen lectured on“Research trends of Immunotoxicology in the USA.”The 1st volume of the “JSIT Newsletter” was issued
in 1996 as the official newsletter of JSIT, which wasthen issued semi-yearly. From the 12th volume
issued in 2008, the English pages were edited
partially in the “JSIT Newsletter” in response to
the maturation of the collaboration between JSIT
and SOT IMTox-SS. In this issue, Dr. Kenneth L.
Hastings contributed his participation report for the
14th annual meeting of JSIT. SOT 2010 in Salt
Lake City was the first annual meeting co-chairedby IMTox-SS and JSIT.
As indicated above, I introduce the origins

President of JIST: Takahiko Yoshida M.D.,
Ph.D., Asahikawa Medical University

Fall 2016

4

JSIT
Contribution
Articleof JSIT and the collaboration between JSIT and IMTox-SS on the occasion of the start of periodical
contribution to the IMTox-SS Newsletter from JSIT. JSIT is composed of nearly 300 scientists working
in academia, industry, and government agencies, and holds an annual meeting around autumn. I
am working as the 5th president of JSIT whose tasks include acceding and prospering the history of
the organization. Although JSIT is a relatively small group, we exchange knowledge and have active
discussions at a particular venue. Lastly, I hope our collaboration will develop into a long and mutually
rewarding relationship.

ProgramCommittee
UpdateFellow Immunotoxicologists; the 2017 Annual Meeting in Baltimore is fast approaching. The ITSS
Program Committee has been working hard since the 2016 SOT meeting to bring you an exciting andinformative program for the 2017 meeting. The table below provides the date/time for the sessions that
ITSS is proud to be sponsoring for the 2017 meeting. In addition, there are several additional sessions(including poster sessions) pertaining to immunotoxicology included for your reference. Mark your calendars and see you soon in Baltimore!

Immunotoxicology Specialty Section

Fall 2016

5

ProgramCommittee
UpdateAs our President advised, it is certainly not too early to think about sessions that you might want tosubmit for the 2018 SOT Annual Meeting. The deadline for submission of 2018 session proposals to SOT
is in May of 2017, only a few short weeks after the SOT Annual Meeting. In general, proposals that areendorsed by one or more specialty sections have a higher probability of being chosen by the Scientific
Program Committee (not always, but it does help immensely). To facilitate endorsements, the ITSS
Program Committee needs your session proposals almost immediately after the 2017 Annual Meeting. We
will send out requests and reminders, but please, to streamline the process and increase the probabilityof your session proposal being selected, send your sessions for endorsement by the ITSS Program
Committee deadline. Please contact Jamie DeWitt, ITSS VP Elect and 2018 Program Committee Chair(dewittj@ecu.edu), with your session ideas! Sessions include continuing education courses, roundtables,
symposia, and workshops.

Immunotoxicology Specialty Section

Fall 20166

Member
Spotlight
Paige Lawrence, Ph.D. is an ITSS member and a professor at the Universityof Rochester, holding appointments in the Departments of Environmental Medicine
and Microbiology & Immunology. Recruited from Washington State University,
Paige has been a faculty member at the University of Rochester for 10 years,
serving as the Director of the Toxicology Training Program and the Deputy Directorof Environmental Health Sciences Center. She enjoys mentoring, and two of her
former PhD students are current ITSS Executive Committee members (Drs. Kristen
Mitchell and Haley Neff-LaFord).
Throughout her career, immunotoxicology has been a consistent componentof Paige’s research, for which a major focus is to determine how immune system development andfunction are altered by environmental exposures. Currently she is working on an exciting project thatblends together the fields of immunotoxicology and developmental toxicology, by investigating how early
exposures affect the immune system not only later in life, but also across multiple generations. Her interestin this developed in part from her belief that immune system needs more coverage in developmental
toxicology studies. The aryl hydrocarbon receptor (AHR) in particular receives considerable attention in
Paige’s research, as it is plays a critical role in regulating the nature of immune responses, and binds avariety of chemicals.
Paige recently put together an international conference on AHR research, which is a huge undertaking
and a major achievement, to say the least. Her interest in organizing the meeting precipitated from her
experiences attending large conferences, where although there has been a lot of growth in the field in thelast 10 years, the AHR research within these meetings was often very spread out. “What motivated me
to do it was a desire to bring the field together”. A success by many accounts, the meeting was held from
August 3-6 in Rochester, NY. It was well attended, with people traveling from across the USA, and from
17 other countries spanning 6 continents. Her decision to hold the meeting in Rochester was not only forpractical “home base” reasons, but it was also fitting because several keystone discoveries about AHR
were made at the University of Rochester. When asked what was the most fun aspect of organizing aninternational meeting, her response was that, as far as the planning component goes, she really enjoyedstrategizing about the science in the sessions. However, she indicated that the very best part was themeeting itself.The positive energy and interpersonal interactions during event provided a reward that she
thought was the most gratifying aspect. She hopes that this meeting will become sustainable, and has
already handed off the reins for the next meeting, slated for Paris in 2018.

AHR
Conference
2016

Immunotoxicology Specialty Section

Fall 2016

7

Job
Opportunities••

A Postdoctoral Scholar position is available immediately in the laboratory of David Lawrence at The
Wadsworth Center of New York State Department of Health (Albany, NY) to study the role of autoantibodies and glia involvement of neuroinflammation affecting behavior. The NIH funded study isdesigned to examine immune complexes and phagocytosis in the alteration of neuronal connectivity. Antibody specificities and isotypes as well as FcRs are of interest regarding the numbers anddistribution of glia and the expression of cytokines, chemokines, neuropeptides and neurotransmitters. The laboratory is interested in several aspects of membrane biology and signal transduction inleukocyte biology. The perinatal influences of environmental stressors, including physical/psychological stress is an important consideration.
The Lawrence Lab is a well-equipped facility with instrumentation for PCR, Fluorescence, Phosphofluorescence, and Chemiluminescence Imaging, Flow cytometry, Luminex analysis, ELISA,ELISPOT and GCSPR/GCSPCE. In addition, The Center has support cores for biomedical research projects (see http://www.wadsworth.org/research/cores). We are seeking a Ph.D. graduate
with training and a demonstrated publication record in immunology and/or neuroscience (preferably
Neuroimmunology), tissue culture and fluorescence microscopy. Applicants should have experience with basic molecular biology techniques including protein, RNA, and DNA preparations, immunoassays, Western blotting, RT-PCR, and PCR. Opportunities for professional growth include
microassay technology. Applicants must have a PhD degree or equivalent and a record of publication. English proficiency is required. Salary scaled according to experience.   Your application
should include a letter describing your research experience and interests, future career aspirations,
your CV, and contact information for three references. Email the requested information to david.
lawrence@health.ny.gov.

Exciting
News
Lorraine Twerdok, Ph.D., a semi-retired ITSS member, was elected to a Councilor position for her local chapter of SOT, the National Capital Area Chapter(NCAC). She will serve for a three year term. Although Dr. Twerdok had servedin several NCAC Board positions in the 1990’s, including chapter President.
She encourages other semi- or fully retired members of SOT who want to stay
involved in their lifelong profession to consider donating their time to their Local
Chapter, Specialty Section(s), or Special Interest Group(s) if experienced scientist volunteers are needed.

Valerie H Adams, Ph.D., a biologist for the US Army Public Health Center,
Health Effects Division; Toxicology, recently passed the DABT.

Immunotoxicology Specialty Section

Fall 20168

Recent
Immunotoxicology
Publications

Compiled by Angela Groves. Anytime you have a new fully-published or electronically-available article
to report, please send the citation to Angela at angela_groves@urmc.rochester.edu.
Asthma, Allergy, Autoimmunity & Hypersensitivity
Canbaz, D., Lebre, M.C., Logiantara, A., van Ree, R. and van Rijt, L.S., 2016. Indoor pollutant hexabromocyclododecane enhances house dust mite-induced activation of human monocyte-derived dendritic
cells. Journal of Immunotoxicology, pp.1-7.
Coenraads, P.J., Vogel, T.A., Blömeke, B., Goebel, C., Roggeband, R. and Schuttelaar, M.L.A., 2016.
The role of the antioxidant ascorbic acid in the elicitation of contact allergic reactions to p-phenylenediamine. Contact dermatitis, 74(5), pp. 267-72.
Hennen, J. and Blömeke, B., 2016. Keratinocytes improve prediction of sensitization potential and potency of chemicals with THP-1 cells. ALTEX.
Kock, M., Coenraads, P.J., Blömeke, B. and Goebel, C., 2016. Continuous usage of a hair dye productcontaining 2-methoxymethyl-para-phenylenediamine by hair-dye-allergic individuals. British Journal of
Dermatology, 174(5), pp.1042-1050.
Kuiper, J., Moran, M. and Cetkovic-Cvrlje, M., 2016. Exposure to polychlorinated biphenyl-153 decreases incidence of autoimmune Type 1 diabetes in non-obese diabetic mice. Journal of Immunotoxicology,
pp.1-11.
Nishino, R., Fukuyama, T., Watanabe, Y., Kurosawa, Y., Koasaka, T. and Harada, T., 2016. Detection of
respiratory allergies caused by environmental chemical allergen via measures of hyper-activation anddegranulation of mast cells in lungs of NC/Nga mice. Journal of Immunotoxicology, 13(5), pp.676-685.
O’Brien, E., Spiess, P.C., Habibovic, A., Hristova, M., Bauer, R.A., Randall, M.J., Poynter, M.E. and van
der Vliet, A., 2016. Inhalation of the reactive aldehyde acrolein promotes antigen sensitization to ovalbumin and enhances neutrophilic inflammation. Journal of immunotoxicology, 13(2), pp.191-197.
Pot, L.M., Coenraads, P.J., Blömeke, B., Puppels, G.J. and Caspers, P.J., 2016. Real-time detectionof p-phenylenediamine penetration into human skin by in vivo Raman spectroscopy. Contact dermatitis, 74(3), pp.152-158.
Zahir, A., Kindred, C., Blömeke, B., Goebel, C. and Gaspari, A.A., 2016. Tolerance to a Hair Dye Product Containing 2-Methoxymethyl-P-Phenylenediamine in an Ethnically Diverse Population of P-Phenylenediamine-Allergic Individuals. Dermatitis, 27(6), pp.355-361.
Developmental Immunotoxicology
Ashley-Martin, J., Lavigne, E., Arbuckle, T.E., Johnson, M., Hystad, P., Crouse, D.L., Marshall, J.S. andDodds, L., 2016. Air Pollution During Pregnancy and Cord Blood Immune System Biomarkers. Journalof Occupational and Environmental Medicine, 58(10), pp.979-986.
Immunotoxicology Specialty Section

Fall 20169

Recent
Immunotoxicology
Publications

Pang, Y., Dai, X., Roller, A., Carter, K., Paul, I., Bhatt, A.J., Lin, R.C. and Fan, L.W., 2016. Early Postnatal Lipopolysaccharide Exposure Leads to Enhanced Neurogenesis and Impaired Communicative
Functions in Rats. PloS one, 11(10), p.e0164403.
Poulet, F.M., Wolf, J.J., Herzyk, D.J. and DeGeorge, J.J., 2016. An Evaluation of the Impact of PD-1
Pathway Blockade on Reproductive Safety of Therapeutic PD-1 Inhibitors. Birth Defects Research Part
B: Developmental and Reproductive Toxicology, 107(2), pp.108-119.
Shivanna, B., Maity, S., Zhang, S., Patel, A., Jiang, W., Wang, L., Welty, S.E., Belmont, J., Coarfa, C.
and Moorthy, B., 2016. Gene Expression Profiling Identifies Cell Proliferation and Inflammation as thePredominant Pathways Regulated by Aryl Hydrocarbon Receptor in Primary Human Fetal Lung Cells
Exposed to Hyperoxia. Toxicological Sciences, 152(1), pp.155-68.
General Immunotoxicology
Yucesoy B, Talzhanov Y, Michael Barmada M, Johnson VJ, Kashon ML, Baron E, Wilson NW, Frye
B, Wang W, Fluharty K, Gharib R, Meade J, Germolec D, Luster MI, Nedorost S (2016). Associationof MHC region SNPs with irritant susceptibility in healthcare workers. Journal of Immunotoxicology,
13:738-744.
Alam, A., Puri, N. and Saxena, R.K., 2016. Uptake of poly-dispersed single-walled carbon nanotubes
and decline of functions in mouse NK cells undergoing activation. Journal of Immunotoxicology, 13(5),pp.758-765.
Dhital, S., Stokes, J.V., Park, N., Seo, K.S. and Kaplan, B.L., 2016. Cannabidiol (CBD) induces functional Tregs in response to low-level T cell activation. Cellular Immunology.
Dornbos, P., Crawford, R.B., Kaminski, N.E., Hession, S.L. and LaPres, J.J., 2016. The Influence of
Human Interindividual Variability on the Low-Dose Region of Dose-Response Curve Induced by 2, 3, 7,
8-Tetrachlorodibenzo-p-Dioxin in Primary B Cells. Toxicological Sciences, 153(2), pp.352-60.
Feng, Y., Tian, J., Xie, H.Q., She, J., Xu, S.L., Xu, T., Tian, W., Fu, H., Li, S., Tao, W. and Wang, L.,2016. Effects of Acute Low-Dose Exposure to the Chlorinated Flame Retardant Dechlorane 602 andTh1 and Th2 Immune Responses in Adult Male Mice. Environmental Health Perspectives, 124(9),pp.1406-13.
Hossain, M.M., Liu, J. and Richardson, J.R., 2016. Pyrethroid insecticides directly activate microglia
through interaction with voltage-gated sodium channels. Toxicological Sciences, p.kfw187.
Jin, Y., Wu, Y., Zeng, Z., Jin, C., Wu, S., Wang, Y. and Fu, Z., 2016. Exposure to oral antibiotics induces
gut microbiota dysbiosis associated with lipid metabolism dysfunction and low-grade inflammation in
mice. Toxicological Sciences, 154(1), pp.140-152.
Kado, S., Chang, W.W., Chi, A.N., Wolny, M., Shepherd, D.M. and Vogel, C.F., 2016. Aryl hydrocarbon
receptor signaling modifies Toll-like receptor-regulated responses in human dendritic cells. Archives of
Toxicology, pp.1-13.
Immunotoxicology Specialty Section
Fall 201610

Recent
Immunotoxicology
Publications
Kielsen, K., Shamim, Z., Ryder, L.P., Nielsen, F., Grandjean, P., Budtz-Jørgensen, E. and Heilmann, C.,
2016. Antibody response to booster vaccination with tetanus and diphtheria in adults exposed to perfluorinated alkylates. Journal of immunotoxicology, 13(2), pp.270-273.
Lichter, J., Bock, U., Lotz, C., Groeber, F. and Blömeke, B., 2016. Functional expression of N-acetyltransferase 1 (NAT1) in differentiated human skin keratinocytes. British Journal of Dermatology.
Maiuri, A.R., Breier, A.B., Turkus, J.D., Ganey, P.E. and Roth, R.A., 2016. Calcium Contributes to the
Cytotoxic Interaction Between Diclofenac and Cytokines. Toxicological Sciences, 149(2), pp.372-384.
Mangum, L.H., Crow, J.A., Stokes, J.V., Howell, G.E., Ross, M.K., Pruett, S.B. and Chambers, J.E.,
2016. Exposure to p, p′-DDE Alters Macrophage Reactivity and Increases Macrophage Numbers in
Adipose Stromal Vascular Fraction. Toxicological Sciences, 150(1), pp.169-77.
Regenass-Lechner, F., Staack, R.F., Mary, J.L., Richter, W.F., Winter, M., Jordan, G., Justies, N., Langenkamp, A., Garrido, R., Albassam, M. and Singer, T., 2016. Immunogenicity, Inflammation, and Lipid
Accumulation in Cynomolgus Monkeys Infused with a Lipidated Tetranectin-ApoA-I Fusion Protein.
Toxicological Sciences, 150(2), pp. 378-89.
Rosas, L.E., Elgamal, O.A., Mo, X., Phelps, M.A., Schmittgen, T.D. and Papenfuss, T.L., 2016. In vitro
immunotoxicity assessment of culture-derived extracellular vesicles in human monocytes. Journal of
Immunotoxicology, pp.1-14.
Taheri, M., Mehrzad, J., Afshari, R., Saleh-Moghaddam, M. and Mahmudy Gharaie, M.H., 2016. Inorganic arsenic can be potent granulotoxin in mammalian neutrophils in vitro. Journal of Immunotoxicology, 13(5), pp.686-693.
Téllez-Bañuelos, M.C., Haramati, J., Franco-Topete, K., Peregrina-Sandoval, J., Franco-Topete, R. andZaitseva, G.P., 2016. Chronic exposure to endosulfan induces inflammation in murine colon via β-catenin expression and IL-6 production. Journal of Immunotoxicology, pp.1-8.
Usui, T., Meng, X., Saide, K., Farrell, J., Thomson, P., Whitaker, P., Watson, J., French, N.S., Park, B.K.
and Naisbitt, D.J., 2016. Characterization of isoniazid-specific T-cell clones in patients with anti-tuberculosis drug-related liver and skin injury. Toxicological Sciences, p.kfw218.
Vallières, F., Simard, J.C., Noël, C., Murphy-Marion, M., Lavastre, V. and Girard, D., 2016. Activation ofhuman AML14. 3D10 eosinophils by nanoparticles: Modulatory activity on apoptosis and cytokine production. Journal of Immunotoxicology, pp.1-10.
Zhang, Y., Yu, X., Sun, S., Li, Q., Xie, Y., Li, Q., Zhao, Y., Pei, J., Zhang, W., Xue, P. and Zhou, Z.,
2016. Cadmium modulates hematopoietic stem and progenitor cells and skews toward myelopoiesis inmice. Toxicology and Applied Pharmacology, 313, pp.24-34.
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Recent
Immunotoxicology
Publications

Methods/Models
Jackman, J.A., Mészáros, T., Fülöp, T., Urbanics, R., Szebeni, J. and Cho, N.J., 2016. Comparison ofcomplement activation-related pseudoallergy in miniature and domestic pigs: foundation of a validatable
immune toxicity model. Nanomedicine: Nanotechnology, Biology and Medicine, 12(4), pp.933-943.
Sato, K., Yuta, K. and Kusaka, Y., 2017. Skin Sensitization Model Based on Only Animal Data by Qualitative Structure-Toxicity Relationships (QSTR) Approach. In Allergy and Immunotoxicology in Occupational Health (pp. 93-101). Springer Singapore.
Reviews/Books/Commentaries
Boule, L.A. and Lawrence, B.P., 2016. Influence of Early-Life Environmental Exposures on Immune
Function Across the Life Span. In Environmental Influences on the Immune System (pp. 21-54). Springer Vienna.
DeWitt JC, Germolec DR, Luebke RW, and Johnson VJ. (2016). Associating Changes in the Immune
System with Clinical Diseases for Interpretation in Risk Assessment. In: Current Protocols in Toxicology(67:18.1.1-18.1.22).
Hessel, E.V., Ezendam, J., van Broekhuizen, F.A., Hakkert, B., DeWitt, J., Granum, B., Guzylack, L.,
Lawrence, B.P., Penninks, A., Rooney, A.A. and Piersma, A.H., 2016. Assessment of recent developmental immunotoxicity studies with bisphenol A in the context of the 2015 EFSA t-TDI. Reproductive
Toxicology, 65, pp.448-456.
Otsuki, T., Petrarca, C. and Di Gioacchino, M., 2016. Allergy and Immunotoxicology in Occupational
Health.
Shvedova, A., Pietroiusti, A. and Kagan, V., 2016. Nanotoxicology ten years later: Lights and shadows.
Toxicology and applied pharmacology, 299, pp.1-2.

Announcement

Late Breaking Abstracts: January 12, 2017
Early Bird Registration: January 13, 2017
Standard Registration: February 10, 2017
Final Registration: After February 10, 2017
Immunotoxicology Specialty Section

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Immunotoxicology Specialty Section
Committee Lists – 2016/2017
Awards Committee:

Program Committee:

Haley Neff-LaFord, Chair
Marpe Bam
Rod Prell
Robert Li
Gautham Rao
Bethany Winans

Jamie DeWitt, Chair
Marpe Bam
Willian Becker
Saurabh Chatterjee
M. Firoze Khan
Rochelle Mikkelsen
Ashwini Phadnis-Moghe
Berran Yucesoy
Brian Zhou

*These were Program Committee members
during 2016. We are accepting new members for
2017.
Education Committee:
Jamie DeWitt, Chair
Cheryl Rockwell
Yu Feng
Aimee Hillegas
Bassam Kashgari
Ashwini Phadnis
Susan McKarns
Alex Turley
Joe ZagorskiCommunications & Membership Committee:
Kristen Mitchell
Angela Groves
Jiajun (Brian) Zhou

If you would like to join a committee, there are still openings on the Communications & Membership and Education Committees.
Please contact the ITSS Secretary/Treasurer or the Chairperson of the committee(s) if you areinterested in joining.

Immunotoxicology Specialty Section

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