3P066!

!

"#$%&'()'*+,-. /01/ 2345
6789:;<=>?! @ABCD! EFBGH! IJBK! LMLM

NOP! !"#$%&'%()*#+,-./0123456789:SERS;#<=>?@34A
BCDEFGHIJKL0KMNMOPQRST$%UVFWXKL0Y#SERSZ[F\]^L_`abcde0< fg*Ehij5kl(EBL)-./0mhn7o p q-r s#tOaS$%
ufv(wxFWXKL0Y#yz12{5D|7(LSP)#}~12-WXKLSAM#SERSZ[F-KL_`abM0Q_ 100nm-1!m#h7$%u f:PS;o p q-     @- K0Y#1 2- _RaS T  (**, NSOL)Y#MMSERSop_`aPQv[1]0NSOL¡^PS#¢£¡¤¥¦R0opq-§KLaST$%¨©ª#rs«d_yz12{5D|7:LSP;#¬­®¯°±0²³f#¬­´µKa¦R 10 7 -10 8 #SERS34¶a$%ufh
ij5kl(NSL)[1]F·^L_`ab¸a`¹0mhB(SiO 2 )$%uf12-?º»RSWX0m¼½UV#¾Kvuf#°± -./0¿À¡^ÁÂÃMRÄÅ`®¯ÆÇR#LSP¬­YLÈÉÊË³ÌF+Í^L_`a[2]b´PR0¦L^#ÎQFST#ÏÐ v? º»È¥aÍ-0ST $%UVÑ 12-ÒÓ @-WXKLaÔKvufÕX¯#SERSZ[-Öda×Ø-`_¹0¦LMRÙ³ÚÛKL_`O`.Ü-ÝÞ
Labßà¹¦LMR0á-â´³fÊËãä#Í#34ABCDE-`_åæ_[3]b¦¦R¹0çNSL0NSOL#12WÕvÔK#°±0YL-.aSAMvDNAèo
OéêÑ³f#SERSZ[#ëìåæbí-0mhB$%ufopÉî-ïæ_0SvðÏÐ-ñ^LaítOòÕUVY#yz{5D|7¬­óHSERSZ[Áô-õö¥ab

NQRP! mhB$%uf¹0Duke ÷#øùuf: 500nm;úb5ûxü5-ýþÿ$%uf³8¡^#£!É"Ë°±#R#$%&':3(4 );#Ó*-./0â

uf+WXåæb¦#12- Ag M¹ Au tOaopîË,¾R012#ÔK-#×ØbFDTD:Finite Difference Time Domain;Q-./0¶^L NSOLUV# LSP ¬­vy.</01å`ãë2s30ÔK#Öda LSP ¬­óH SERS
34Ë-#×Ø-`_b !

NSTUVWP! 1)ü5op#4½Bh56v0$%uf#1256:B½78m½o9Ö;./0:O;<#O`=>>©#?@-ÅFæST**v$%¨©ª

WXF¿AR¸a¦F0AFM0SEM BC-./D¡Í^Lb !
2)PSR¹0Y#EF@G[#Í-uf#H[,IJ[FÉ%0ufK-LufÕX¯
S TFM Nv¥%0 ¾>100nmR¹**O ÑFOFæU VOab¦L-P_0SiO 2 R¹0ufQûD#e^¹vv:`F0Y#R[#Í-ufK¹STU
RVW_X/0$%ufÈLSPBw{h7j#YZ-./[_`ab3)**\#opîË¹0&`PF]f#^8_°¥a¦R012ÔK`

K%Ra¦Fa^¡-Oæbí-S12R¹0¾ 20nm #<0bRcd-efOFWXKLb12ÔKF3:¥a0X.Y 700nm ./g®¯h- LSP ²i#j*'FäLaF0efOR¹ 800nm ./¯®¯-¡²ij*'¹äLO`bXY^%klR¹$%ufQûD./Lmæ`KOòÕ-X¯ST#no LSP Y#Bw{½ LSP F0plR¹$%uf#¯qrRBw{½ LSP -.a²iF0s@-BëKLaÍtd^Lab4)opîË 100-200bR¹0efOopq#uvÕ¹O%tO/0w2xy# 100-200nm#s 3@ ` KO0" Vò Õ U V ÑFWXKLab¦#0: 2 N #$%z{w{? @F
WXKL_X/0òÕUVÑK#|}@OLSPBw{h7j~¥abã-0extinction'½ëìåÜ0&î# 470, 520, 570, 900 nm#j*'-P_0ÉîR¹¬405, 470, 520, 620 (Ag¾t Ag =20nm)-670 (t Ag =50nm)0g®¯mkFBëKLb&îR#LSP¬­'½¹01 »- 4 #Ag-NSOLuf-`_#FDTD01

.%P_`abO¡^ 600nm./g®¯#LSP¬­¹à#STNSOLuf#m¼½UV-.aLSP¬­R¸/0¯®¯h 900nm9"#(*xO7x¹ufK#LSP¬­-.abÉîR¹0900nm#ÄÅ`j*'F:%g®¯mk_X/0¦L¹¡^òÕ-#Ag$%**#WÕ«-.%P_`a[4]b5)NSOL#12-\CuPc(k(m4C7)0PNTP:p-nitrothiophenol;#SERS34ëì¦ 10 4 -10 5 #2F¶^LbM0PNTP¹â³f# 1/1000 zRLëìR0£

Á#PNTPË4Ë#¡^010 -11 MMR#¤F¿AR¸a¦FÁ-z¥a 4 #DNAèo#,¤[FD¡Í^LbM0hab-£'x:A-A-A-A-A-SH; A: 4C7;¸^¡ ÍAg-NSOL-xìqR0£

Á

¡^T-T-T-T(T: ¡7)³f¢ûhwxK0Y#£¤in situR¤Ra¦FD¡Í
^Lb¦#S¡4¡%¥vh{x#²,AFa^¡-Oæb6;K^-¦§¨`¦-0NSOL # SERS ¹0&î-s]_ 100-200b#Éî\10 ©"%:O SERS 34ËF¶^LbM0488nm v 514.5nm -s]_ 632.8nm }~R¹ 10-40 ©L:O3 4ËF¶ ^La¦F a:ü5op-# S T #òÕ #SERS 34Ë./L 2 ª¤Ë:`;b¦L¹0òÕWX-./ LSP ¬­F 600nm 9"-g
® ¯ mk  0 632.8nm } ~ R | } @ O¬ ­ F ã ä KLa¦ -.a t d^Lab

FDTD y.</01#« ¬q#

L¦Ls_`a[4]b0opîË-./12ÔK°±¥a¦R0NSOLQ-./­®./L 10 2 ©¤Ë:OSERSZ[F¶^La¦Fabì³-#SERS##Í-yO
td^Lab

XVYZ!
1) M. A. Young, J. A. Dieringer, R. P. Van Duyne, in NANO-OPTICS and NANO-PHOTONICS,(Eds.) S. Kawata & V. M. Shalaev (Elsevier, 2007) 1-40. óH¯°±.
2) H. Wang et al, Acc. Chem. Res. 40 (2007) 53.
3) M. Futamata, Y. Maruyama, in “Tip Enhancement”, S. Kawata, V. M. Shalaev (Eds.), 2007(Elsevier), pp. 41-86.
4) M. Futamata, et al. to be submitted.