FLORA FUCOIDAN
Selected Okinawan ingredient mix to boost the power of gut
NANO
FUCOIDANOKINAWA MOZUKUFUCOIDAN

Utilize liposome technology

GREEN
PAPAYAFERMENTEDPAPAYA

Okinawa mozuku fucoidan has been reported for numerous advantages, immunostimulatory activity
anti tumor activity and more. Hopeful for this multiplier effect with the immunity activity lactic acidbacteria has.

OKINAWA MOZUKUFUCOIDANFUCOIDAN

By patented technique, encapsulating fucoidan with phospholipids at the nanoscale range. It is
expected that the absorption rate will increase, the medicinal properties within the gastrointestinal
environment will be protected and the taste of the product will be improved.

GREEN
PAPAYAIn green papaya is rich in vitamins, minerals and polyphenol and eaten as vegetable in Okinawa. Our
green papaya powder can be used for dairy product because papain activity is deactivated.

FERMENTEDPAPAYA

By bio technology extract and lactic ferment numerous active ingredients contained in green papaya.
By fermentation, encourage Bifidobacterium growth.

NANO

Encourage Bifidobacterium and lactic acid bacteria growth

Add nothing75Add flora fucoidan

16183119 28

strain-A

strain-B

strain-C

cfu/g dilution ratio 107

Confirmed great growth

Add nothing

Add flora fucoidan

Bifidobacterium growth test

Lactic acid bacteria growth test

Confirmed growth in a few
strain of lactic bacteria

Add nothing156

Add flora fucoidan

38

add nothing add flora fucoidan
cfu/g dilution ratio 107

What is Fucoidan
Fucoidan is a water soluble polysaccharide in agroup of brown algae as like mozuku.
Kanehide Bio selected Okinawa mozuku on
purpose in brown algae group and refine fucoidan.
Because it contain high purity fucoidan and isexcellent uniformity.
Fucoidan has reported its numerous advantages
by several thesis as like antitumor,immunostimulatory, antiviral, anti helicobacterand improving bloodstream.

FucoseSulfategroup

Glucuronic acid
Fig. Structural formula of Fucoidan from Mozuku

Fucoidan is compatible with lactic acidbacteria and Bifidobacteriums-IgA secretion speed in saliva（㎍/mins.）

Increased secretory component(s-IgA) byingested fucoidan continuously
350

300

Increased s-IgA in saliva
after 4 weeks intake

１５５％250219 **212 **

199 **

200150128 **

100048Ingested term（weeks）

12**p＜0.01

Secretory IgA (s-IgA) plays an important role in the protection andhomeostatic regulation of intestinal, respiratory, and urogenital mucosal
epithelia separating the outside environment from the inside of the body.
s-IgA prevent viral infection or bacterium into upper respiratory tract inoral, expected encourage immune system in oral by increasing amount ofsecretory IgA (secretion speed). Kanehide Bio Co., Ltd. gain a patent for theuse of active which fucoidan encourage secrete s-IgA.(patent number:6446422).
【Test Sample】●Fucoidan in capsule●5 capsules in a day ( contained 1,175mg of Okinawa mozuku extract)【Research subjects】●22 healthy people ( 11male, 11 female)●From 20 years old to 65 years old ( average 42.3 ±10.4 years old)
●Slowing secretions of secretory IgA(s-IgA)

Summary of Flora Fucoidan
Product nameRaw materials
Package unit
Best before
Final production
Form

Flora Fucoidan
Mozuku extract, dextrin, indigestible dextrin, papaya juice,
fermented papaya extract / lecithin (Soybean derived)
10kg/box
2 years after the date manufactured
Japan (Okinawa)
PowderUse example
Supplements for gut health,immune booster or probiotic drinks

Ratio

30％ Fucoidan
30％ Papaya fruits juice powder
30％ Fermented papaya extract powder
10％ NANO Fucoidan
You can customize your preference ratio refer the use.

＜CONTACT＞

TEL: 098-994-1001
FAX: 098-994-0636
5-2-2 Nishizaki Itoman Okinawa 9010306, JAPANhttps://www.kanehide-bio.co.jp/