The 8th Annual Meeting of JSIT
2001.9.17-18.
Tochigi Prefectural Culture Center (Utsunomiya)President: Fujio Kayama (Jichi Medical School)
Special Lecture
Strategies for the safetyassessment of geneticallymodified foods, including theirallergenic potential

Harry A. Kuiper, Gijs A.
Kleter, Hub P.J.M. Noteborn
and Esther J. Kok

RIKILT, Wageningen
University &Research Center(WUR)

Symposium
Movement for the Safety
Securing of Genetically Modified
Foods with Domestic andOversea Views.

National Food ResearchInstituteK. Isshiki

Diagnosis and Management ofFood Allergy.

Dept. of Pediatrics, Graduate
School of Medicine, Chiba
Y. Kohno
University

Allergenicity study of geneticallymodified food.

Div. of Biochemistry andImmunochemistry, NationalInstitute of Health Sciences

R. Teshima

Workshop

Application of the mouse
popliteal lymph node assay to
immunotoxicological evaluationof drugs.

(1)Immunotoxicology
Working Group, Preclinical
Evaluation Subcommittee,
Drug Evaluation Committee,
Japan Pharmaceutical
ManufactureｒsAssociation(2)Sankyo Co., Ltd.

T. Kimura(2)，T.
Aida(2)，K.
Nagami(1)，K.
Watanabe(1)，K.
Tanaka(1)，H.
Irie(1)，M.
Yokota(1)，A.
Suda(1)，K.
Nakamura(1)Collaborative study to establish
immunotoxicology evaluation
procedures for pharmaceuticals;
Correlation between flowcytometric analysis andpathological examination.

Safety Research Res. Dep.,
Teikoku Hormone Mfg. Co.,Ltd.

S. Hisada

Collaborative study to establish
immunotoxicology evaluation
procedures for pharmaceuticals;
correlation between
hematologic/pathologic changes
and specific anitibodyproduction.

Safety Research Labs.,
Yamanouchi PharmaceuticalCo., Ltd.

K. Hoshino

Collaborative study to establish
immunotoxicology evaluation
procedures for pharmaceuticals;
correlation between flow-Drug Safety Research Lab.,
Daiichi Pharmaceutical Co.,Ltd.

H. Hattoricytometric analysis and specificantibody production.
Collaborative study to establish
immunotoxicology evaluation
procedures for pharmaceuticals;
comparison of dosing periods (14days and 28 days)

Biosafety Research Center,Foods, Drugs and Pesticides

D. MukaiGeneral Presentation
Investigation of In Vitro
Antigenicity Testing Method byUsing Mouse Dendritic Cells; In
vitro Induction of Proliferation
and Differentiation of DendriticCells.

Dept. Preclinical Science,
Nippon Roche Research

T. Inoue，I. HoriiCenter

Developmental Research
M. Nagata，M.
Flow Cytometric Analysis of BoneLaboratories, Shionogi & Co., Hino，K. Kanasaki，Marrow Differentials.
Ltd.
K. Nakamura
Flow Cytometric Assay for NK
Cell Activity Using DiOC18 Dye.

Developmental Research
K. Kanasaki，M.
Laboratories, Shionogi & Co., Nagata，M. Hino，
Ltd.
K. Nakamura

Immunotoxicological Evaluationof Environmental Chemicals
Utilizing Mouse Lymphocyte
Mitogenesis Test

Division of Environmental
Health, Faculty of
Pharmaceutical Sciences,
Setsunan University, andDepartment of Biophysics,
Graduate School of
Pharmaceutical Sciences,
Kyusyu University

H. Sakazaki(1)，H.
Ueno(1)，K.
Umetani(1)，K.
Nakamuro(1)，H.
Utsumi(2)Effects of indomethacin andcyclophosphamide on serum
immunoglobulin levels andlymphoid organs in SRBCimmunized rats.

Safety Research Dep.,
Teikoku Hormone Mfg. Co.,Ltd.

S. Hisada，M.
Nagashima，H.
Tanifuji，S. Shibata.

Determination of concentrationsof solvents forPLNA.

Hashima Laboratory, Nihon
Bioresearch Inc.

Y. Yamada，I.
Asano，T. Koike

Effect of Tributyltin on hostdefence system of mice.

(1)Dept. Biomedical Food
Research, National Instituteof Infectious Diseases(2)Dept. of Phamacology,
Osaka Phamacology, College(3)Dept. of Parasitic Agents
Kobe Institute of HealthY. SugitaKonishi(1)，F.
Amano(2)，Y.
Sugiura(3)Organophosphorus Pesticides
Decrease Natural Killer (NK),Lymphokine-Stimulated Killer(LAK) and Cytotoxic T
Lymphocyte (CTL)Activities via
Granzymes Inactivation.

Department of Hygiene andPublic Health, Nippon
Medical School

Q. Li，N.
Nagahara，Y.
Hirata， M.
Minami.

Predisposition and Preceding
Factors of "Occupational
Allergyin Doctors"in Medical
Students: the 2nd Report.

Dept. of Environmental
Health, School of Medicine,
Fukui Medical University

K. Sato，Y. Kusaka

Immunological Analyses ofFrom Environmental Medical

K. Sakabe(1)，M.

Center, The Kitasato

Miyata(1)，S.

Institute, Environmental

Ishikawa(1)，W.J.

Patient with Chemical Sensitivity. Health Center-Dallas,

Anti-Cedar Pollen/Dermatophagoides IgA in saliva
and Allergic Symptoms.

Yoshida(3)，F.

and Jichi Medical School.

Kayama(4)Department of Social andEnvironmental Medicine F1,

S. Tsujita，K.

Osaka University Graduate

Morimoto

School of Medicine(1)Asahikawa Medical

Evaluation of the immune
parameters for assessment ofenvironmental risk on humanRea(2)，T.

Asahikawa Medical CollegeCollege，(2)Faculty of
Pharmacological Science,
Teikyo University，(3)National Institute ofhealth. -Field research on 3years
Health Sciences，(4)Hatanoold childrenResearch Institute, Food &Drug Safety Center.

T. Yoshida(1)，T.
Ito(1)，Y.
Nakagi(1)，M.
Ohsawa(2)，K.
Takahashi(2)，F.
Ohtsuka(2)，J.
Sawada(3)，R.
Teshima(3)，K.
Kojima(4)Reproductive Immunotoxicity of
di-2ethylhexylphthalate(DEHP)in
Mice.

(1)Molecular Pharmacology& Pharmacotherapeutics，(2)Geriatric Pharmacology &Therapeutics, Graduate
School of PharmaceuticalSciences, Chiba University

Study on the suppressive effectsof dioxin on the antibody
production.

K. Nohara(1)(2)，K.
(1)National Institute forInoue(1)(3)，T.
Environmental Studies，Ito(1)(2)，H.
(2)CREST, JST，(3)Domestic
Fujimaki(1)(2)，C.
Research Fellow ,JSTTohyama(1)(2)

Effect of bisphenol on nonspecitic defence system of mice.

Y. Shinozaki(1)，K.
Ogita(1)，T.
Nakamura(1)，S.
Yano(1)，K.
Ueno(2)(1)Dept. of Veterinary
Medicine, Azabu university，
S. Shimura(1)，(2)Dept. of Phamacology,
T.Nishikawa(1)，Y.
OsakaSuzuki(1)，F.
Phamacology,College，Amano (2)，Y.
(3)Dept. Biomedical Food
Sugita-Konishi(3)Research, National Instituteof Infectious Diseases

Transcriptional regulation ofestrogen receptors in precursor
B cells.

Safety & Analytical ResearchCenter, POLA ChemicalIndustries, Inc.

Growth enhancement of IL-6R
highly expressing myeloma cells(1)Dept. Hyg, (2)Div.
Hematol., Dept. Intern.

Sakaguchi(1)，A.
Ueki(1)，K.

by ThalidomideMed., Kawasaki Med. Sch.

Yata(2)，T.
Sugihara(2)S. Hirokawa
T. Otsuki(1)，H.

Apoptosis of thymic lymphocytes
in mice induced bydiphenylhydantoin exposure

Effect of Drugs on the Specific
Antibody Production of Offspring

Koichi Hayashi，Tadashi Kosaka，Institute of environmental
toxicology

Yukiko Takeuchi，Koichi Ebino，ShojiTeramoto，Takanori
HaradaDevelopmental Research
M. Hino，M.
Laboratories, Shionogi & Co., Nagata，K.

after Prenatal Exposure in Rats.

Ltd.

Nakamura
S. Ueda，A. Igari，

Effect of fourimmunosuppressive drugs on
glomerular and tubulointerstitiallesions of nephrotoxic serum
nephritis in mice.

Dep. of Drug Information &Communication, Graduate

M. Chen，T.
Kawanabe，N.
Sato，M. Manabe，School of Pharmaceutical
Scieences, Chiba University

H. Asai，M.
Yasuda，S.
Yamagata，N.
Satoh