Timetable
June 30 (Thu) : Day 1
RoomRoom 1
[1F]

9:00

10:00

Opening Remarks
9:25~9:30

11:00

Invited Lecture (IL)The Potential ofEnvironmental Toxicology
for Promoting One Health
Hisato IWATA
9:30~10:30

12:00

13:00

Special Lecture (SL)
Effects of methylmercury
exposure on fetuses
Mineshi SAKAMOTO
10:45~11:45

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e21

Symposium 1 (S1)Further Development of MPS:Over the Devil River and Valley of Death

Room 2[1F]

9:30~11:30
e21

Symposium 2 (S2)Case study: Is the information on the ontarget toxicity of knockout mouse useful for thedevelopment of the candidate compound?

Room 3[1F]

Lunchtime Seminar(L1-3)SEKISUI MEDICAL CO., LTD.
12:00~13:00

9:30~11:30
e22e91

Symposium 3 (S3)Current genotoxic research: Hazard
identification and risk assessment forprotection against genome instability

Room 4[2F]

Lunchtime Seminar(L1-4)
Veritas Corporation
12:00~13:00

9:30~11:30
e22e91

Symposium 4 (S4)Further utilization of clinical and non-clinical CDISC
standard data in new drug development

Room 5[2F]

Lunchtime Seminar(L1-5)Charles River
12:00~13:00

9:30~11:30e23e92

Symposium 5 (S5)KSOT-JSOT Joint Symposium:
Update on lung toxicity

Room 6[2F]

Lunchtime Seminar(L1-6)
Labcorp Development Japan K.K.
12:00~13:00

9:30~11:30
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Symposium 6 (S6)Impact assessment of chemicals on environmentalorganisms

Room 7[2F]

Lunchtime Seminar(L1-7)
Elsevier Japan K. K.
12:00~13:00

9:30~11:30

Room 8[2F]

Poster&Exhibition
Room[1F]（P-1E）Pharmaceutical drugs(chemicals)（P-3E）Biopharmaceuticals（P-4E）Agricultural chemicals（P-8E、P-10E、P-12E）Metals（P-17E、P-19E、P-21E、P-22E）
Environmental pollutants（P-25E）Nanomaterials（P-32E、P-34E、P-35E）Liver（P-48E、P-49E）Other organs orsystem

e24Lunchtime Seminar(L1-8)

Candidates for the Excellent
Presentation Award (Oral) 1

Poster Installation
9:00~10:00

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LPIXEL Inc.
12:00~13:00

9:30~11:06
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Candidates for the Excellent Presentation Award (Poster) & Student Poster Award (P-1E~100S)
Poster Viewing
10:00~17:30

Commercial Exhibition
10:00~18:30

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14:00

15:00

16:00

17:00

Symposium 7 (S7)
JSTP-JSOT Joint Symposium:
Carcinogenicity evaluation in rasH2 -Tg(tg/wt) miceSymposium 8 (S8)Assessment for individual susceptibilities todrug on drug safety research

13:30~15:30

15:30~17:30
e27CM
1Symposium 10 (S10)
Development of new nanomaterial assessment
methodologies for inhalation, immunological andcardiovascular toxicities

Symposium 9 (S9)Cytokine release syndrome still linger with
antibody therapy
13:30~15:30

15:30~17:30

Symposium 11 (S11)JSOT-JCA Joint Symposium:
Molecular basis for the evolution of the evaluation
methods of carcinogenic potentials 2.0
13:30~15:30

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Symposium 12 (S12)
JSCT-JSOT Joint Symposium:
Recent trends in basic study and clinicalapplication of the cutting-edge technology
for vital sign monitoring
15:30~17:30

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Symposium 13 (S13)Current status and prospects of adverse events
research in humans utilizing computer science
13:30~15:30

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Symposium 14 (S14)
New aspects of thalidomide study:
toward elucidation of species difference basedon metabolism
15:30~17:30

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Workshop 1 (W1)
Current status of in vitro research leading drug
discovery and development safety research

Symposium 15 (S15)
Examples, prospects and social meaningof Chrono-toxicology

13:30~15:30

15:30~17:30
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Workshop 2 (W2)
Clinical adverse events/side
Symposium 16 (S16)
Gene / cell therapy development and effects that are difficult to detectin general toxicity studies -newits safety assessment
approaches from nonclinical
13:30~15:00
research Part I (General remarks)e32

15:00~16:00

Symposium 17 (S17)
Overview of Big Projects on New
Approach methods in Japan
16:00~17:30

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Symposium 18 (S18)
Biometals Specialty Section Symposium-Approaches to elucidate the mechanisms involvedin the arsenic toxicity-

Workshop 3 (W3)
Points to consider in selecting a starting dose levelfor first-in-human clinical trials of novel therapeuticmodalities from safety and efficacy perspectives

13:30~15:30

15:30~17:30
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Candidates for （P-51E、P-52E、P-55E）
Reproductive anddevelopmental toxicology
the Excellent（P-59E）Genetic toxicology
Presentation Award （P-60E）Carcinogenicity（P-63E、P-64E）(Oral) 2
Immunotoxicology
13:30~14:18

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19:00

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CM
2

18:00

（P-66E）Cytotoxicity

e34（P-70E）Mechanisms oftoxicity（P-75E）Cellular response（P-80E）Biomarkers（P-81E）Toxicity-testing
methods（P-85E、P-91E、P-93E、P-94E）Alternatives tomammalian models（P-95E）Clinical toxicology

Candidates for
the Excellent
Presentation Award(Oral) 3
16:10~17:04
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Candidates for the Excellent Presentation Award (Poster) & Student Poster Award (P-1E~100S)
Poster Viewing
10:00~17:30

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Poster Presentation /Discussion (CoreTime)(P-1E~100S)
17:30~18:30

PosterRemoval
18:30~19:00

Commercial Exhibition
10:00~18:30

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July 1 (Fri) : Day 2
Room

Room 1
[1F]

9:00

10:00

Educational Lecture 1 (EL1)
Safety evaluation of
medicinal drug as a life
science
Ikuo HORII
9:00~9:50

Room 2
[1F]

11:00

12:00

13:00

Symposium 19 (S19)
Microsampling:
Current Status and Foresight
10:00~11:30

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Lunchtime Seminar(L2-2)

Symposium 20 (S20)Children's toxicology: factors of dysplasia of brain function

Central Institute forExperimental Animals
12:00~13:00

9:00~11:30
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Room 3[1F]

Educational Lecture 2 (EL2)
Symposium 21 (S21)
Environmental
Risk assessment and risk communication regarding
Toxicology
in Anthropocene the administration of medicines and breastfeeding

Lunchtime Seminar(L2-3)
Axcelead Drug Discovery
Partners, Inc.
12:00~13:00

9:50~11:50

Chiho WATANABE
9:00~9:50 e38

Room 4
[2F]

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Lunchtime Seminar(L2-4)

Symposium 22 (S22)Up-to-Date of Laboratory Animal Study- Outreach & Well-being -Shin Nippon Biomedical
Laboratories, Ltd.
12:00~13:00

9:00~11:30
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Room 5[2F]

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Symposium 23 (S23)
Risk management and countermeasures for the aggravationand sequelae of COVID-19

Lunchtime Seminar(L2-5)Charles River
12:00~13:00

9:00~11:30
e40

Room 6[2F]

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Symposium 24 (S24)Novel Aspects of Developmental Toxicity Mechanisms of Dioxins
and Related Compounds

Lunchtime Seminar(L2-6)NIKON CORPORATION
12:00~13:00

9:00~11:30
e40

Room 7[2F]

Symposium 25 (S25)
Oral Session 1
International symposium : Anti-Drug Conjugates(O-1~O-4)(ADCs), Exosomes - Perspectives from Researchers
11:00~11:48
and Regulatory Scientists on these new Modalities（O-1、O-2、O-3）Skinof Drug Delivery（O-4）Respiratory system
9:00~11:00

Room 8[2F]

Poster&Exhibition
Room[1F]

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Oral Session 2(O-5~O-9)

Oral Session 3(O-10~O-14)

9:00~10:00（O-5）Metals（O-6、O-7）Nanomaterials（O-8）Biopharmaceuticals（O-9）Radiation

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Eurofins Discovery
12:00~13:00

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Oral Session 4(O-15~O-19)

10:00~11:00（O-10、O-11、O-12、O-13）
Oxidative stress（O-14）Inﬂammation

Lunchtime Seminar(L2-7)

11:00~12:00

e43（O-15、O-16）Alternatives tomammalian models（O-17、O-18、O-19）Animal modele43

Poster Installation

Poster Session (P-101~185) Poster Viewing

9:00~10:00

10:00~16:50

Commercial Exhibition
10:00~17:35

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14:00

15:00

General Assembly,Award Ceremony
13:10~14:50

16:00

17:00

18:00

19:00

Award Lecture
The JSOT Award
The JSOT Young Scientist Award
14:50~16:30
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Symposium 26 (S26)
Application of advanced in vitro humanized modelfor Drug Safety research
14:50~16:50
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Workshop 4 (W4)Novel strategy for exposome
14:50~16:50
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Symposium 27 (S27)
Next Generation Research Seminar:
New Intersection of Forensic Science and Toxicology
14:50~16:50
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Workshop 5 (W5)
Let's discuss the current status and challenges ofnon-clinical safety assessment in the early stages ofdrug development

Banquet Party
Sapporo Beer Garden
18:45~20:15

14:50~16:50
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Symposium 28 (S28)
Biometals Specialty Section Symposium:
Frontiers of elemental analysis
supporting the research in toxicology
14:50~16:50
e48

Symposium 29 (S29)
On the frontline of Wildlife Toxicity Assessment by
Young Researchers
14:50~16:50
e48

Symposium 30 (S30)
Research Approaches Towards Accurate
Developmental Neurotoxicity Assessment
14:50~16:50
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Poster Session (P-101~185) Poster Viewing
10:00~16:50

Poster Presentation /Discussion (Core Time)(P-101~185)
16:50~17:35
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PosterRemoval
17:35~18:05

Commercial Exhibition
10:00~17:35

e7July 2 (Sat) : Day 3
RoomRoom 1
[1F]

9:00

10:00

11:00

12:00

Symposium 31 (S31)
New direction of read-across approach:
From safety evaluation and regulatory use to drug repositioning

13:00

Award Ceremony of the Excellent
Presentation Award & Student Poster Award
11:30~11:45

9:00~11:30
e50

Room 2[1F]

Educational Lecture 3 (EL3)
Destructive innovation ofCvaccine R&D under COVID-19Mpandemic3
Ken J ISHII
9:00~9:50

Room 3[1F]

Symposium 32 (S32)
A new approach to non-clinical safetyassessment of biopharmaceuticals
9:50~11:50

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Symposium 33 (S33)
SOT-JSOT Joint Symposium: Latest insight into metal
toxicity at the molecular level9:00~11:00

Oral Session 5(O-20~O-23)

Lunchtime Seminar(L3-3)

11:00~11:48（O-20、O-21、O-22、O-23）
Nervous system

MIMETAS Japan K.K. /Molecular Devices Japan KK
12:00~13:00

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Oral Session 6(O-24~O-27)

Room 4[2F]Symposium 34 (S34)
11:00~11:48
Usefulness of 3D culture model of RPTEC -aiming to（O-24）Industrial chemicals
predict renal pharmacokinetics and toxicity（O-25、O-26）Environmental
9:00~11:00

e52

Room 5[2F]

pollutants（O-27）Agricultural chemicals

Lunchtime Seminar(L3-4)
Instem Japan K.K.
12:00~13:00

e53

Symposium 35 (S35)
Potential of small fish (zebrafish and medaka) as next-generation
experimental animals-a new player in toxicology

e98

Lunchtime Seminar(L3-5)Charles River
12:00~13:00

9:00~11:50
e53

Room 6[2F]

Oral Session 7
Symposium 36 (S36)(O-28~O-33)
Evaluation of health impact and10:30~11:30
development of quality assessment （O-28）Epidemiology（O-29）Risk
methods of foods and food additives communicationassessment and（O-30、O-31）Organoid
toward ensuring food safety
9:00~10:30

Room 7[2F]

Lunchtime Seminar(L3-6)
Shin Nippon Biomedical
Laboratories, Ltd.
12:00~13:00（O-32）AOP（adverse outcome pathway）

e54 （O-33）Drug-metabolizing enzyme e55

e99

Oral Session 8(O-34~O-37)

Symposium 37 (S37)
Male reproductive toxicity up to date

11:00~11:48

9:00~11:00
e56（O-34）General toxicology（O-35、O-36、O-37）
Reproductive anddevelopmental toxicology

Symposium 38 (S38)
11:00~11:48
Recent drug application and toxicity evaluation in（O-38、O-39）Cellular
the eyes
response
9:00~11:00

e57

Poster&Exhibition
Room[1F]

FUJIFILM Wako Pure
Chemical Corporation
12:00~13:00（O-40）Epigenetics（O-41）Biomarkers

e100

Lunchtime Seminar(L3-8)LSIM Safety InstituteCorporation
12:00~13:00

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Poster Installation

Poster Session (P-186~276) Poster Viewing

9:00~10:00

10:00~14:00

Commercial Exhibition10:00~14:00

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Lunchtime Seminar(L3-7)

e56

Oral Session 9(O-38~O-41)

Room 8
[2F]

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Poster Presentation /Discussion(Core Time)(P-186~276)
13:00~13:45
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14:00

15:00

16:00

17:00

Symposium 39 (S39)
Immunotoxicity of chemical substances:mechanism elucidation and its prevention

Closing Remarks
16:30~16:35

14:00~16:30
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Symposium 40 (S40)
Toward further progress of 3Rs in animal
experiments
14:00~16:00
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Symposium 41 (S41)
AI-Driven Biology and Toxicology
14:00~16:30
e60

Educational Lecture 4 (EL4)Symposium 42 (S42)
Global Assessment
Progress and Future Prospects of Researchof the Impacts ofon Environmental Risk Assessment ofPharmaceutical Pollution
Human Pharmaceuticals
Alistair BOXALL
14:00~14:50 e61

14:50~16:30
e61

Symposium 43 (S43)
Maternal hypothyroidism and developments of intelligencein children
14:00~16:30
e61

Symposium 44 (S44)
Clinical adverse events/side effects that are difficult to detectin general toxicity studies -new approaches from nonclinicalresearch Part II (Specifics)
14:00~16:30
e62

Workshop 6 (W6)
Active career of Toxicologists-What value does a PhD bring to
the toxicologist?14:00~15:00

Symposium 45 (S45)
ICH E14/S7B Q&A Update
and Prospects
15:00~16:30

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Workshop 7 (W7)
Non-clinical Safety study Issues in Pediatric Drug
Development
14:00~16:00
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Poster Session (P-186~276) Poster
Poster Viewing
Removal
10:00~14:00 e82 14:00~14:30

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