nCounter Prep Plate

Safety Data Sheet

Section 1: Identification of the Substance/Mixture and of the Company/Undertaking
1.1 Product identifier
Product Name•

Synonyms• BCIST Prep Plate; Dx Prep Plate; Elements Prep Plate; Life Science Reagent PlatenCounter Prep Plate

1.2 Relevant identified uses of the substance or mixture and uses advised against
Relevant identified use(s)Use(s) advised against• Post-hybridization processing and purification• This product is not intended for use in humans or animals.

1.3 Details of the supplier of the safety data sheetManufacturer• NanoString Technologies
530 Fairview Avenue North
Seattle, WA 98109
United States
www.nanostring.com
safetycommittee@nanostring.com
Telephone (General) • 206.378.NANO (6266)

1.4 Emergency telephone number
Manufacturer• 206.378.NANO (6266)

Section 2: Hazards Identification
EU/EEC

According to: Regulation (EC) No 1272/2008 (CLP)/REACH 1907/2006 [amended by 2015/830]

2.1 Classification of the substance or mixture
CLP• Not classified

2.2 Label Elements
CLP

Hazard statements • No label element(s) required

2.3 Other Hazards
CLP• According to Regulation (EC) No. 1272/2008 (CLP) this material is not consideredhazardous.

UN GHS Revision 4

According to: UN Globally Harmonized System of Classification and Labelling of Chemicals (GHS): Fourth
Revised Edition
Preparation Date: 11/May/2018
Revision Date: 20/September/2018

LBL-C0010-04

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2.1 Classification of the substance or mixture
UN GHS• Not classified

2.2 Label elements
UN GHS

Hazard statements • No label element(s) required
Precautionary statements

2.3 Other hazards
UN GHS• According to the Globally Harmonized System for Classification and Labeling (GHS)
this product is not considered hazardous

United States (US)

According to: OSHA 29 CFR 1910.1200 HCS

2.1 Classification of the substance or mixture
OSHA HCS 2012

• Not classified

2.2 Label elements
OSHA HCS 2012

Hazard statements • No label element(s) required

2.3 Other hazards
OSHA HCS 2012

• This product is not considered hazardous under the U.S. OSHA 29 CFR 1910.1200
Hazard Communication Standard.

CanadaAccording to: WHMIS 2015

2.1 Classification of the substance or mixture
WHMIS 2015• Not classified

2.2 Label elements
WHMIS 2015

Hazard statements • No label element(s) required
Precautionary statements

2.3 Other hazards
WHMIS 2015

• In Canada, the product mentioned above is not considered hazardous under the
Workplace Hazardous Materials Information System (WHMIS).

Section 3 - Composition/Information on Ingredients
3.1 Substances• Material does not meet the criteria of a substance.

3.2 Mixtures
Preparation Date: 11/May/2018
Revision Date: 20/September/2018

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ChemicalName

Composition
Identifiers%

LD50/LC50

Component
A

NDA

38% TO
48%

NDA

Component B

NDA

8% TO 10%

NDA

Component C

NDA

10% TO
15%

NDA

Component D

NDA

15% TO
20%

NDA

Component E

NDA

15% TO
20%

NDA

Component F

NDA

1% TO 10%

NDA

ComponentG

CAS:26628-22-8
EC Number:247852-1
EU Index:011-00400-7<0.000009%

Ingestion/Oral-Rat LD50 •27 mg/kg
Skin-Rabbit LD50 • 20 mg/kg

Classifications According toRegulation/Directive
EU CLP: Not Classified
UN GHS Revision 4: Not Classified
OSHA HCS 2012: Not Classified
WHMIS 2015: Not Classified
EU CLP: Not Classified
UN GHS Revision 4: Not Classified
OSHA HCS 2012: Not Classified
WHMIS 2015: Not Classified
EU CLP: Not Classified
UN GHS Revision 4: Not Classified
OSHA HCS 2012: Not Classified
WHMIS 2015: Not Classified
EU CLP: Not Classified
UN GHS Revision 4: Not Classified
OSHA HCS 2012: Not Classified
WHMIS 2015: Not Classified
EU CLP: Not Classified
UN GHS Revision 4: Not Classified
OSHA HCS 2012: Not Classified
WHMIS 2015: Not Classified
EU CLP: Not Classified
UN GHS Revision 4: Not Classified
OSHA HCS 2012: Not Classified
WHMIS 2015: Not Classified
EU CLP: Union workplace exposure limit
OSHA HCS 2012: Exposure limit

Comments
NDA

NDA

NDA

NDA

NDA

NDA

NDA

Section 4 - First Aid Measures
4.1 Description of first aid measures
Inhalation
Skin
EyeIngestion• Move victim to fresh air. Administer oxygen if breathing is difficult. Give artificial
respiration if victim is not breathing.
• In case of contact with substance, immediately flush skin with running water for atleast 20 minutes.
• In case of contact with substance, immediately flush eyes with running water for atleast 20 minutes.
• If swallowed, rinse mouth with water (only if the person is conscious) If large quantities
are swallowed, call a physician immediately.

4.2 Most important symptoms and effects, both acute and delayed• Refer to Section 11 - Toxicological Information.

4.3 Indication of any immediate medical attention and special treatment needed
Notes to Physician• All treatments should be based on observed signs and symptoms of distress in thepatient. Consideration should be given to the possibility that overexposure to materials
other than this product may have occurred.

Section 5 - Firefighting Measures
Preparation Date: 11/May/2018
Revision Date: 20/September/2018

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5.1 Extinguishing media

Suitable Extinguishing Media • LARGE FIRE: Water spray, fog or regular foam.
SMALL FIRES: Dry chemical, CO2, water spray or regular foam.
Unsuitable Extinguishing• No data available.
Media

5.2 Special hazards arising from the substance or mixture
Unusual Fire and Explosion
Hazards
Hazardous Combustion
Products• Some may burn but none ignite readily.
• No data available.

5.3 Advice for firefighters• Move containers from fire area if you can do it without risk.
Wear positive pressure self-contained breathing apparatus (SCBA).
Structural firefighters' protective clothing provides limited protection in fire situations
ONLY; it is not effective in spill situations where direct contact with the substance ispossible.
Wear chemical protective clothing that is specifically recommended by themanufacturer. It may provide little or no thermal protection.

Section 6 - Accidental Release Measures6.1 Personal precautions, protective equipment and emergency procedures
Personal Precautions
Emergency Procedures• Ventilate enclosed areas. Do not walk through spilled material. Use appropriate
Personal Protective Equipment (PPE)• Keep unauthorized personnel away. Stay upwind.

6.2 Environmental precautions• Avoid run off to waterways and sewers.

6.3 Methods and material for containment and cleaning up
Containment/Clean-up
Measures• Stop leak if you can do it without risk.
SMALL SPILLS: Take up with sand or other non-combustible absorbent material andplace into containers for later disposal.
LARGE SPILLS: Dike far ahead of liquid spill for later disposal.

6.4 Reference to other sections• Refer to Section 8 - Exposure Controls/Personal Protection and Section 13 - Disposal
Considerations.

Section 7 - Handling and Storage
7.1 Precautions for safe handling
Handling• Handle in accordance with good industrial hygiene and safety practice. Wearrecommended Personal Protective Equipment when handling.

7.2 Conditions for safe storage, including any incompatibilities
Storage

7.3 Specific end use(s)• Keep container tightly closed and store at recommended temperature.
• Refer to Section 1.2 - Relevant identified uses.

Section 8 - Exposure Controls/Personal Protection
8.1 Control parameters
Preparation Date: 11/May/2018
Revision Date: 20/September/2018

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Exposure Limits/Guidelines

ResultComponent G(26628-22-8)

ACGIH

0.29 mg/m3 Ceiling (as Sodium azide); 0.11 ppm CeilingCeilings(as Hydrazoic acid vapor)

NIOSH

0.1 ppm Ceiling (as HN3); 0.3 mg/m3 Ceiling (as NaN3)

8.2 Exposure controls
Engineering
Measures/Controls• Good general ventilation should be used. Ventilation rates should be matched toconditions. If applicable, use process enclosures, local exhaust ventilation, or otherengineering controls to maintain airborne levels below recommended exposure limits.
If exposure limits have not been established, maintain airborne levels to an acceptablelevel.
Personal Protective Equipment
Respiratory• In case of insufficient ventilation, wear suitable respiratory equipment.
Eye/FaceSkin/Body
Environmental ExposureControls• Wear protective eyewear (goggles, face shield, or safety glasses).
• No protective clothing expected to be needed.
• Follow best practice for site management and disposal of waste.

Key to abbreviations
ACGIH = American Conference of Governmental Industrial Hygiene
NIOSH = National Institute of Occupational Safety and Health
STEL = Short Term Exposure Limits are based on 15-minute exposures
TWA= Time-Weighted Averages are based on 8h/day, 40h/week exposures

Section 9 - Physical and Chemical Properties
9.1 Information on Basic Physical and Chemical Properties
Material Description
Physical Form

LiquidAppearance/Description

Odorless liquid.

Color

Data lacking

Odor

Odorless

Odor Threshold

Data lacking

Boiling Point

Data lacking

Melting Point/Freezing Point

Data lacking

Decomposition Temperature

Data lacking

pH

Data lacking

Specific Gravity/Relative Density

Data lacking

Water Solubility

Data lacking

Viscosity

Data lacking

Explosive Properties

Data lacking

Oxidizing Properties:

Data lacking
Vapor Density

Data lacking

General Properties

Volatility

Vapor Pressure

Data lacking

Evaporation Rate

Data lacking

Flammability
Flash Point

Data lacking

UEL

Data lacking

LEL

Data lacking

Autoignition

Data lacking

Flammability (solid, gas)

Data lacking

Environmental

Octanol/Water Partition coefficient Data lacking

9.2 Other Information• No additional physical and chemical parameters noted.

Preparation Date: 11/May/2018
Revision Date: 20/September/2018

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Section 10: Stability and Reactivity
10.1 Reactivity• No dangerous reaction known under conditions of normal use.

10.2 Chemical stability• Stable

10.3 Possibility of hazardous reactions• Hazardous polymerization will not occur.

10.4 Conditions to avoid• No data available.

10.5 Incompatible materials• Strong oxidizing agents.

10.6 Hazardous decomposition products• Thermal decomposition can lead to release of irritating and toxic gases and vapors.
Carbon oxides.

Section 11 - Toxicological Information
11.1 Information on toxicological effects
GHS Properties

Classification

Acute toxicity

EU/CLP • Data lacking
UN GHS 4 • Data lacking
OSHA HCS 2012 • Data lacking
WHMIS 2015 • Data lacking

Skin corrosion/Irritation

EU/CLP • Data lacking
UN GHS 4 • Data lacking
OSHA HCS 2012 • Data lacking
WHMIS 2015 • Data lacking

Serious eye damage/Irritation

EU/CLP • Data lacking
UN GHS 4 • Data lacking
OSHA HCS 2012 • Data lacking
WHMIS 2015 • Data lacking

Skin sensitization

EU/CLP • Data lacking
UN GHS 4 • Data lacking
OSHA HCS 2012 • Data lacking
WHMIS 2015 • Data lacking

Respiratory sensitization

EU/CLP • Data lacking
UN GHS 4 • Data lacking
OSHA HCS 2012 • Data lacking
WHMIS 2015 • Data lacking

Aspiration Hazard

EU/CLP • Data lacking
UN GHS 4 • Data lacking
OSHA HCS 2012 • Data lacking
WHMIS 2015 • Data lacking

Preparation Date: 11/May/2018
Revision Date: 20/September/2018

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Carcinogenicity

EU/CLP • Data lacking
UN GHS 4 • Data lacking
OSHA HCS 2012 • Data lacking
WHMIS 2015 • Data lacking

Germ Cell Mutagenicity

EU/CLP • Data lacking
UN GHS 4 • Data lacking
OSHA HCS 2012 • Data lacking
WHMIS 2015 • Data lacking

Toxicity for Reproduction

EU/CLP • Data lacking
UN GHS 4 • Data lacking
OSHA HCS 2012 • Data lacking
WHMIS 2015 • Data lacking

STOT-SE

EU/CLP • Data lacking
UN GHS 4 • Data lacking
OSHA HCS 2012 • Data lacking
WHMIS 2015 • Data lacking

STOT-RE

EU/CLP • Data lacking
UN GHS 4 • Data lacking
OSHA HCS 2012 • Data lacking
WHMIS 2015 • Data lacking

Potential Health Effects
Inhalation
Acute (Immediate)
Chronic (Delayed)

Skin

Acute (Immediate)
Chronic (Delayed)

Eye

Acute (Immediate)
Chronic (Delayed)

Ingestion

Acute (Immediate)
Chronic (Delayed)• Under normal conditions of use, no health effects are expected.
• No data available.
• Under normal conditions of use, no health effects are expected.
• No data available.
• Under normal conditions of use, no health effects are expected.
• No data available.
• Under normal conditions of use, no health effects are expected.
• No data available.

Section 12 - Ecological Information
12.1 Toxicity• Material data lacking.

12.2 Persistence and degradability• Material data lacking.

12.3 Bioaccumulative potential• Material data lacking.

12.4 Mobility in Soil
• Material data lacking.
Preparation Date: 11/May/2018
Revision Date: 20/September/2018

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12.5 Results of PBT and vPvB assessment• No PBT and vPvB assessment has been conducted.

12.6 Other adverse effects• No studies have been found.

Section 13 - Disposal Considerations
13.1 Waste treatment methods
Product waste• Dispose of content and/or container in accordance with local, regional, national, and/orinternational regulations.
• Dispose of content and/or container in accordance with local, regional, national, and/orinternational regulations.

Packaging waste

Section 14 - Transport Information
14.1 UN
number

14.2 UN proper
shipping name14.3 Transport hazard
class(es)14.4 Packing
group

14.5 Environmentalhazards

DOT

Not Applicable

Not Regulated

Not Applicable

Not Applicable

NDA

TDG

Not Applicable

Not Regulated

Not Applicable

Not Applicable

NDA

IMO/IMDG

Not Applicable

Not Regulated

Not Applicable

Not Applicable

NDA

IATA/ICAO

Not Applicable

Not Regulated

Not Applicable

Not Applicable

NDA

14.6 Special precautions foruser
14.7 Transport in bulk
according to Annex II ofMarpol and the IBC Code• None specified.
• Data lacking.

Section 15 - Regulatory Information
15.1 Safety, health and environmental regulations/legislation specific for the substance or
mixtureComponent
Component GComponent
Component GCASMA

26628-22-8

Yes

State Right To Know

Inventory

NJ

PA

Yes

Yes

CAS

Canada DSL

Canada NDSLEU EINECS

EU ELNICS

TSCA

26628-22-8

Yes

NoYes

NoYes

CanadaLabor

Canada - WHMIS 1988 - Classifications of Substances• Component G

26628-22-8

D1A

Canada - WHMIS 1988 - Ingredient Disclosure List• Component G

26628-22-8

1%Preparation Date: 11/May/2018
Revision Date: 20/September/2018

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Environment

Canada - CEPA - Priority Substances List
• Component G

26628-22-8

Not Listed

U.S. - OSHA - Process Safety Management - Highly Hazardous Chemicals• Component G

26628-22-8

Not Listed

U.S. - OSHA - Specifically Regulated Chemicals• Component G

26628-22-8

Not Listed

26628-22-8

Not Listed• Component G

26628-22-81000 lb final RQ; 454 kg final
RQ

U.S. - CERCLA/SARA - Radionuclides and Their Reportable Quantities• Component G

26628-22-8

Not Listed

U.S. - CERCLA/SARA - Section 302 Extremely Hazardous Substances EPCRA RQs• Component G

26628-22-81000 lb EPCRA RQ

26628-22-8

500 lb TPQ (this material is areactive solid, the TPQ does
not default to 10000 pounds
for non-powder, non-molten,non-solution form)• Component G

26628-22-8

1.0 % de minimis
concentration

U.S. - CERCLA/SARA - Section 313 - PBT Chemical Listing• Component G

26628-22-8

Not Listed

U.S. - California - Proposition 65 - Carcinogens List
• Component G26628-22-8

Not Listed

U.S. - California - Proposition 65 - Developmental Toxicity• Component G

26628-22-8

Not Listed

U.S. - California - Proposition 65 - Maximum Allowable Dose Levels (MADL)• Component G

26628-22-8

Not Listed

U.S. - California - Proposition 65 - No Significant Risk Levels (NSRL)• Component G

26628-22-8

Not Listed

U.S. - California - Proposition 65 - Reproductive Toxicity - Female• Component G

26628-22-8

Not Listed

United StatesLabor

Environment

U.S. - CAA (Clean Air Act) - 1990 Hazardous Air Pollutants• Component G
U.S. - CERCLA/SARA - Hazardous Substances and their Reportable Quantities

U.S. - CERCLA/SARA - Section 302 Extremely Hazardous Substances TPQs
• Component G

U.S. - CERCLA/SARA - Section 313 - Emission Reporting

United States - California
Environment

Preparation Date: 11/May/2018
Revision Date: 20/September/2018

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U.S. - California - Proposition 65 - Reproductive Toxicity - Male• Component G26628-22-8

Not Listed

15.2 Chemical Safety Assessment• No Chemical Safety Assessment has been carried out.

Section 16 - Other Information
Revision Date
Preparation Date

• 20/September/2018• 11/May/2018

Disclaimer/Statement ofLiability• The information herein is given in good faith but no warranty, expressed or implied, ismade.

Key to abbreviations
NDA = No Data Available

Preparation Date: 11/May/2018
Revision Date: 20/September/2018

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