CSC & Shipping Expert communities
Improving the understanding of controlled substances and shipping
legislation around the world
Jessie Bin Song, CSC Expert Community Lead, Merck
Jack DeCicco, Shipping Expert Community Lead, GSK
Birthe Nielsen, Expert Community Manager, Pistoia Alliance
Akos Papp, CSCS SC, Chemaxon
Joe Bradley, CSCS SC, Scitegrity

CSCS@pistoiaalliance.org

Controlled Substance Compliance & Shipping
Expert Communities (CSCS)
Problem Statement:
Legislation relating to pharma R&D is changing rapidly; eachchange adds complexity and widened controls. Remaining
compliant in this complex environment is an ever-growing
challenge and consequences for breaches are severe.
Compliance is also important in shipping. Customs, cold chains,
dangerous goods and infectious material legislation all makeR&D shipping complex.

Project manager
cscs@pistoiaalliance.org

Project champions:• Jack DeCicco, GSK (Shipping Expert community)• Jessie Bin Song, Merck (Controlled SubstanceCompliance Expert community)

Steering Committee:

Value Proposition:
High levels of compliance are vital to the credibility of andpublic trust in life science R&D. To assist its members, the CSCS
Expert Communities provide a forum for complianceprofessionals, researchers, compound and shipping managers
to share best practices and update their awareness of newlegislation.

$7K per year ensures a seat on theSteering Committee

Project member:

Project deliverables:

The expert communities are made up of major
pharmaceutical companies and specialist software providers.
It is voluntary for the member companies to share theirknowledge and experience.

•••Round table discussions
Seminars
Discussion and collaboration with expert external
speakers and with independent and quasi-judicial
monitoring bodies

AgendaCollaborate toInnovate
Conference
Boston 2022

•
•
•
•

How does the communities operate
CSC evolvement, mission, and activity highlights
CSC activities: communicating with regulators
Controlled substance screening tools– CS2 and Compliance Checker
Compliance requirements for shipping
Shipping Expert Community Activities
CSCS Outcomes/Tools
How to join the communities© Pistoia Alliance

•
•
•
•

CSC & Shipping History

Requirement

User acceptance

Shipping community

Two active

and GSK) on

gathering and RFP

testing and CSCS

created as separate

communities with

Compounds

publication

implementation

group

quarterly whole

Exchange Standards

2 vendors

completed- CSCS project starts

contracted(Commercially

Exploratory talks (AZteam meetings

available solutions)Pre-project
An Expert System combinedwith a Controlled Substance
Knowledgebase to determine
if a substance is controlled​

2013

2014

Project Process
Chemaxon and Patcore: Compliance Checker
Scitegrity: CS2

2021

2022

2 Expert Communities>20 members from different pharmacompanies© Pistoia Alliance2011-2012

CSC - Mission

The Community focuses on tackling the challenges we face, developing solutions,communicating with regulators, and learning from each other to stay current and© Pistoia Alliancecompliant with legislations governing controlled substance activities.

The Controlled Substance Landscape© Pistoia Alliance… challenges we face▪

Complex and rapid changing legislation▪

Super generic scheduling decision captures significantly more compounds in pharma
libraries and more difficult to interpret▪

Increasing externalization▪

Cultural barrier▪

Small number of internal experts to monitor and interpret the legislation▪

High stakes for non-compliance© Pistoia Alliance

LandscapeUnited Nations - Single Convention on Narcotic Drugs 1961
United Nations - Convention on Psychotropic Substances 1971
United Nations - Convention against the Illicit Traffic in Narcotic Drugs
and Psychotropic Substances 1988
United Kingdom - Misuse of Drugs Act 1971
United States - Controlled Substances Act 1970
United States - Chemical Diversion And Trafficking Act of 1988
Canada - Controlled Drugs and Substances Act 1996
India - Narcotic Drugs and Psychotropic Substances Act, 1985
Singapore – Misuse of Drugs Act
New Zealand – Misuse of Drugs Act 1975
Thailand - Psychotropic Substances Act
Pakistan - Narcotic Drugs and Psychotropic Substances Act, 1985
Australia - Standard for the Uniform Scheduling of Medicines and PoisonsPhilippines - Comprehensive Dangerous Drugs Act of 2002
Russia - Regulations on the State Committee of Russian Federation for thecontrol of narcotic drugs and psychotropic substances
United Arab Emirates - UAE Federal Law 14 of 1995
Japan - Narcotics & Psychotropics Control Law, Stimulants Control Law,
Narcotics Special Law
South Africa - Drugs and Drug Trafficking Act No. 140 of 1992
Iceland - Regulation on habit-forming and narcotic substances and othercontrolled substances No. 233/2001
Gibraltar - Drugs (Misuse) Act 1973
Indonesia – law on narcotics (Law No. 22/1997), law on psychotropics (Law
No. 5/1997)
European Union - Council Decision 2005/387/JHA of 10 May 2005 on theinformation exchange, risk-assessment and control of new psychoactive
substances
European Union - REGULATION (EC) No 273/2004 OF THE EUROPEANPARLIAMENT AND OF THE COUNCIL of 11 February 2004 on drug
precursors
European Union - COUNCIL REGULATION (EC) No 111/2005 of 22
December 2004 laying down rules for the monitoring of trade between theCommunity and third countries in drug precursors

Belgium - Royal Decree of 1930 on narcotic substances and Royal Decree of 1998 on
psychotropic substances
Czech Republic - Law no. 167/1998, On Narcotic Drugs and Psychotropic Substances
Denmark - Executive Order 698 of 1993 on Euphoric Substances
Germany - Narcotics Act (BtMG)
Spain - Order of 8th July 1967 and the Royal Decree 2829/1977
Ireland - Misuse of Drugs Regulations1988
France – Decree Law of 22 February 1990
Netherlands - Opium Act
Portugal - Decree-Law 15/93
Norway - Regulation of 1978
Poland - 1997 Act on Counteracting Drug Addiction
Greece - Law 3459/2006 (Codification of the Drug
Legislation)
Estonia - Regulation No 39 of the Minister of Social Affairsof 4 November 1997
Austria - ‘Narcotic Substances Act’ (Suchtmittelgesetz, abbr. SMG)
Italy - Decree 4 March 1992
Sweden - Narcotic Drugs Punishments Act (1968:64).
Portugal - Decree Law 15/93, of 22 January 1993
Slovenia - Production and Trade in Illicit Drugs Act
Slovakia - Act No. 139/1998
Romania - Law no. 143/2000
Malta - Medical and Kindred Professions Ordinance(Cap. 31), Dangerous Drugs Ordinance (Cap. 101)
Luxembourg - Grand Ducal decrees, 4 March 1974,
20 March 1974, 26 March 1974, 8 May 1993 and 30 January 2004
Lithuania - Law on Narcotic and Psychotropic Substances Control(No.VIII-602; 1998)
Bulgaria - Drugs and Precursors Control Act 1999
Croatia - Law on Combating Narcotic Drugs Abuse 2001
Cyprus - Narcotic Drugs and Psychotropic Substances Law 1977
Finland - Narcotics Act (1289/1993)
Hungary - 1/1968. (V. 12., Government Decree No. 272/2001.(XII.21.), 4/1980. (VI. 24.)
Latvia - Law on Procedures for the Legal Trade of the Narcotic and Psychotropic
Substances, Law on Precursors
Lithuania - Law on Narcotic and Psychotropic Substances Control (No.VIII-602; 1998)© Pistoia Alliance

Complex legislation

Interpretation

Daniel Taylor, Stuart G. Bowden, Reinhard Knorr, Derek R. Wilson, John Proudfoot, Anne E. Dunlop, The Pistoia Alliance Controlled Substance Compliance
Service Project: from start to finish, Drug Discovery Today, Volume 20, Issue 2, 2015, Pages 175-180,© Pistoia Alliance

It is not always easy to know the right answer

Non-compliance is a Business Risk
You really, really don’t want to get wrong▪ DEA issues Two Year Suspension for Wholesale Distributor's Ability to Sell Controlled Substances.
▪ Large Logistics Carrier Pays $40 Million Fine

▪ The wholesale drug distributor To Pay $1 Million To Resolve Allegations of CSA Recordkeeping Violations by
Subsidiary▪ A pharmaceutical company Settles State’s Opioid Claims, Avoids Trial; Settlement May Reach $263 Million▪ A pharmaceutical company settled with DOJ $8 Billion Global Settlement▪ A university agrees to pay $308K to resolve allegations of violations of Controlled Substances Act▪ Manufacturer Self-Discloses Listed Chemical Violations to DEA, Agrees to Pay $25,000 Settlement© Pistoia Alliance▪ Former Drug Distributor CEO Found Guilty of Conspiracy To Distribute Narcotics and To Defraud DEA

Controlled Substance Compliance
Community© Pistoia Alliance… what we doCSC Community Activities
Regulation Monitoring, Enhancing Best Practice
Examples of last 2 years discussions and speaker program
The Evolving
Landscape of
US Controlled
Substance
Regulation PhRMA

Suspicious
Order
Monitoring- IQVIA

Regulatory
Inspections in
Italy, Irelandand UK – The
ComplianceGroup

Defendinganalogue cases-James Felman
International
SampleLogistics-Avantor
Inventory
Management
System –BioviaChineseControlled
Substance
Legislation –MilliporeSigma

China to ban
all synthetic
cannabinoids© Pistoia Alliance

The International
Narcotics Control
Board: Precursor
Controls

Examples of activities….. communicating with regulators© Pistoia Alliance

UK 3rd Generation Cannabinoids

2016 - The UK took a new approach to defining chemical space in UK

Many possible cores + almost any
type of attachments(i)replacement of the indole ring with indane, indene, indazole, pyrrole, pyrazole, imidazole,
benzimidazole, pyrrolo[2,3-b]pyridine, pyrrolo[3,2-c]pyridine or pyrazolo[3,4-b]pyridine;(ii) replacement of the pentyl substituent with alkyl, alkenyl, benzyl, cycloalkylmethyl, cycloalkylethyl, (Nmethylpiperidin-2-yl)methyl, 2-(4-morpholinyl)ethyl or (tetrahydropyran-4-yl)methyl;(iii) replacement of the methanone linking group with an ethanone, carboxamide, carboxylate, methylene
bridge or methine group; ….......

© Pistoia Alliance

Not just a defined core + definedchemical attachments“any compound (not being clonitazene, etonitazene, acemetacin, atorvastatin, bazedoxifene, indometacin,
losartan, olmesartan, proglumetacin, telmisartan, viminol, zafirlukast or a compound for the time being
specified in sub-paragraph (c) above) structurally related to 1-pentyl-3-(1-naphthoyl)indole (JWH-018), in thatthe four substructures, that is to say the indole ring, the pentyl substituent, the methanone linking group andthe naphthyl ring, are linked together in a similar manner, whether or not any of the sub-structures have been
modified, and whether or not substituted in any of the linked sub-structures with one or more univalent
substituents and, where any of the sub-structures have been modified, the modifications of the sub-structures
are limited to any of the following, that is to say—▪ Unfortunately, this led to a large amounts of chemical space inadvertently becoming
controlled▪ Including significant numbers of chemicals in DD screening collections▪ Plus clinical trial candidates with no cannabinoid activity (including cancer drugs)▪ When advised of this the UK regulators response was that the law clearly says these
are controlled, so they are!

15

© Pistoia Alliance▪ Regulators had no power to change this, only licence certain activities (only parliament
can change laws)

The CSCS working group analysed and fed back possible new wording...
...which was subsequently accepted and enacted in law
Old‘and whether or not substituted in any of the linked sub-structureswith one or more univalent substituents’New*https://assets.publishing.service.gov.uk/government/uploads/system/uploads/attachment_data/file/670663/AC
MD_Letter_-_Legitimate_use_of_controlled_drugs_research_and_healthcare_22_Dec_17.pdf© Pistoia Alliance‘and whether or not substituted in any of the linked substructures with a benzyl or phenyl group and whether or not suchcompound is further substituted to any extent with alkyl, alkenyl,
alkoxy, halide, haloalkyl or cyano substituents’▪ Within R&D chemical collections, this typically reduced the chemical
space controlled as Cannabinoids by around 90%.
▪ Also meant several clinical candidates (including cancer drugs)
unintentionally caught by the original wording (and required licences!)were no longer considered controlled▪ Chemical space covered now much more focussed on likely
cannabinoid activity▪ But.... took over 2.5 years (partly due to Brexit). Better to engage earlyand before the regulations come out.

© Pistoia Alliance▪ Increased awareness amongst UK regulators as to the potential impact
on R&D of Controlled Drug regulations and Pistoia's role

Examples of activities… communicating with regulators© Pistoia Alliance

Research Exemptions and de-minimus limits in the UK

Leading on from the 3rd Generation cannabinoids lessons learned▪ UK government commissioned a report on possible research exemptions and reduced licencing
requirements in research "Consideration of barriers to Research, part 1"▪ The Pistoia CSCS group and our member companies, plus the ABPI and others worked together
to submit evidence and opinions from across industry and academia▪ We're not going to get a general research exemption, but maybe reduced requirements forsmaller volumes or simpler licencing▪ UK Advisory Council for the Misuse of Drugs has now published its report, which is now underconsideration by the UK government▪ Initially focussed on synthetic cannabinoids, but the hope is it could be a blue-print for all
controlled drugs in future in the UK© Pistoia Alliance▪ https://www.gov.uk/government/publications/consideration-of-barriers-to-research-part1?utm_medium=email&utm_campaign=govuk-notifications&utm_source=74727d67-1331-4361-944beeb9dfc87836&utm_content=daily

Examples of activities… communicating with regulators© Pistoia Alliance

U.S. Government Accountability Office (GAO) report into Fentanyl Class wide controls

The GAO report specially highlighted and used the Pistoia CSCS groups evidence on the use of class wide
controls (e.g controlling areas of chemical space)"We selected 11 organizations that represent a range of perspectives in the research community,
including those representing professional associations, research institutions, and the pharmaceuticalindustry, as well as researchers. The organizations were:▪ Professional associations and associated researchers: American Society of Addiction Medicine, The College of Problems
on Drug Dependence, and the American Society of Pharmacology and Experimental Therapeutics▪ Research institutions and associated researchers: NMS Labs, RAND, University of California San Francisco, and Scripps
Foundation

organizations: Pistoia Allianceand PhRMA• Research-related interest groups:
Friends of NIDA and Council on
Government Relations© Pistoia Alliance• Pharmaceutical industry research

CSCS commercial tools© Pistoia Alliance

2 commercially available tools developed
Controlled Substances Squared (Scitegrity)
Compliance Checker (ChemAxon)

Controlled Substances Squared

23© Pistoia AlliancePart ofCompliance Hub for Drug Discovery

Controlled Substances SquaredPart ofCompliance Hub for Drug Discovery▪ Covers over 32 jurisdictions / country's globally▪ Not just Controlled Drugs, other research relevant regulations such as strategic export
controlled, PIC Rotterdam, CWC (with Dangerous Goods coming soon)▪ APIs - Automatically check all chemicals you have at the Enterprise level▪ Detailed legislation guidance. Not just if, but also how, why, what to do next..
▪ Search using your own internal chemical IDs▪ Place your own controls or context sensitive overrides▪ Track the controlled status of all your chemicals over time
▪ E-mail support and advice on ‘hits’
24© Pistoia Alliance▪ Weekly legislation checks and updates

Controlled Substances Squared

25© Pistoia AlliancePart ofCompliance Hub for Drug Discovery

Compliance Checker

Compliance Checker
SEARCH ENGINE
INPUT

Any
text in
Searchdefinitionsfile
ChemicalWorkflow tools
API, APIaaSCompliance Checker
INPUT

Any text

Chemical file
Workflow tools
API, APIaaS

SEARCH ENGINE

Search indefinitions

Countries
Austria
Belgium
CanadaChina
Denmark
FranceGermany
India
Ireland
Italy
Japan
Netherlands
Singapure
Spain
SwedenSwitzerland
United Kingdom
United States of AmericaEU

Rotterdam
Convention

Montreal
ProtocolConvention on the
Use of Chemical WeaponsUNCompliance Checker
INPUT

Any text

Chemical file
Workflow tools
API, APIaaS

SEARCH ENGINE

Search indefinitions

Search engine - JChem Engine bygeneric group definitions

Markush structures

Search engine - JChem Engine by
Markush structures

Compliance Checker
INPUT

Any text

Chemical file
Workflow tools
API, APIaaS

OUTPUT
SEARCHENGINE

SearchReport indefinitions
HTML
SDF
XLSX
MRV
PDF

Compliance Checker
INPUT

OUTPUT
SEARCHENGINE

Any text

Report/Response
Search indefinitions
HTML

Chemical file
Workflow tools
API, APIaaS

JSON
MRV
PDF
SDF
XLSX

Compliance Checker
INPUT

Any text

Chemical file
Workflow tools
API, APIaaS

SEARCH ENGINEOUTPUT

Search indefinitions

Report/Response
JSON
HTML
MRV
PDF
SDF
XLSX

API integration

Compliance Checker© Pistoia Alliance

Shipping Expert Community

What’s the Mutual Goal?
Materials arrive in a timely manner & same condition as when the shipment left site▪

Temperature restrictions▪

Compliance aspects – Customs, FDA, HMRC,USDA, Fish and Wildlife, DEFRA, CDC▪

Time to prepare the shipment▪

Time to transport the shipment▪

Routing – Should/Must use preferred LSP▪

Mistakes - Requestor, Shipper, Carrier© Pistoia Alliance

Barriers to the GOAL:

How do we reduce those Barriers?
Goal: Materials arrive in a timely manner and in the same condition as when the
shipment left the site of departure

Reducing Barriers:▪ Awareness to the Process▪ Awareness to the People who Contribute to the Process© Pistoia Alliance▪ Awareness to the Compliance Elements Critical to the Process© Pistoia Alliance

Compliance with regulators

Compliance Elements
What information is needed▪ HS Code▪ INCO Terms▪ Valuation▪ Permits and Licences▪ Country of Origin▪ Denied Party Screening▪ Dangerous Goods▪ Material Description (a catch all element)
42© Pistoia Alliance

All shipments have to be in compliance with local and international regulations. While thesecan vary there are typically 8 items that need to be considered.

HS code

▪
▪
▪
▪
▪

The Harmonized System (HS) of tariff nomenclature is a code that is internationally harmonized and describes theimported item to Customs.
The HS code’s first six digits are harmonized globally (with a few exceptions!)
The HS code determines the amount of duty and tax that is to be charged on the import, it is also the trigger for othergovernment agency’s regulations, for example the FDA. It is also used for statistical purposes.
The HS code should also be included on a shipping invoice.
The HS code is also known as the HTS code, Commodity code and Tariff code
HS codes are primarily used for imports, some countries also have export codes that may or may not be the same
number as the HS code. In the USA this is known as the Schedule B number. The first 6 digits of the code are the sameas the import code.

© Pistoia Alliance▪

Valuation▪
▪

The accurate value of the goods must be listed on the shipping invoice
Nominal values and zero values are NOT acceptable
This is required by globally by Customs
False information is subject to fines and penalties.
▪ Requestor can also be subject to fines and penalties in addition to your company
For R&D material that is produced by your company the value should bedetermined by using an approved method.
For material that is bought in then a purchase order value or market value
should be used

44

© Pistoia Alliance

▪
▪
▪
▪

Permits and Licenses▪
▪
▪

Some shipments will require a permit or license
The need for a permit is determined by the type of material that is being shipped and the country ofexport and/or import
Items most likely to need a permit are animal material of livestock or endangered animal origin,controlled substances, certain equipment and chemicals that may require an export license andother items based on local government regulations
The shipper preparing the material for shipment may determine any permit requirements andshould work with a Compliance Manager to provide the permit or submit the application
Some of the regulatory bodies that may require permits or licenses are;
▪ United States Department of Agriculture (USDA)▪ Centers for Disease Control (CDC)▪ Convention on International Trade in Endangered Species (CITES)▪ Department for Environment, Food and Rural Affairs (DEFRA)▪ China Inspection and Quarantine Services (CIQ)
45© Pistoia Alliance▪
▪

Species Regulated by USDA**(U.S. Department of Agriculture)

Materials derived from animals below will require a USDA permit

▪
▪
▪
▪
▪
▪
▪
▪
▪

4
6

© Pistoia Alliance

Bovine (cattle)
Ovine (sheep)
Caprine (goats)
Cervid (deer)
Porcine (pigs)
Equine (horses)
Avian (birds)
Aquatic farmed species (fish, shell fish)
Pathogens that could impact poultry/livestock and would thus be a concern with regard to USDA:
https://www.aphis.usda.gov/animal_health/downloads/organisms_and_vectors/vsregulatedlivestockpoultryp
athogens_partial%20list.pdf

Species Not Regulated by USDA**(U.S. Department of Agriculture)▪

Dogs and cats▪

Primates▪

Marine mammals (except oils & meals)▪

Wild animals other than ungulates and swine (i.e., bears, badgers,
racoons)▪

Rodents▪

Amphibians and reptiles
47© Pistoia Alliance

Species not regulated under permit must travel with a USDA guideline
statement that is completed on foreign shipper letterhead

Country of Origin

48© Pistoia Alliance▪ Country of origin is the origin of the manufacture or growth of thematerials being shipped which is determined based on the rules of
the importing country.
▪ This is not always the country of export.
▪ This information is used to determine tariff rates, establish
marking/labeling requirements, enforce quotas and compile trade
statistics.
▪ Country of Origin is mandatory for all cross-border shipments andshould be included on import and export documentation

– Export and Sanction controls covers all the export controls that may apply– This can be a screening of the product for dual use or the need for an export
license and also a screening of the individual or company the material is being
received by– The screening is conducted against a global lists of parties or individuals forwhich international trade is restricted for various reasons including being
associated with terrorists or terrorist-supporting organizations, individuals andentities tied to international drug trafficking or proliferation of weapons of mass
destruction; embargoed countries and nationals and their entities; individuals
and businesses on country-specific lists and international organizations.
– The screening should be during initial contract set up with 3rd parties such as
vendors or CROs, etc.
49

© Pistoia Alliance

Restricted Party Screening / Sanctions andExport Controls

Dangerous Goods••••

Many items shipped or received can be considered Dangerous Goods, the transport of dangerous
goods is regulated by local and international regulations
There is specific training that needs to be taken before a person can offer material that is adangerous good for transportation
Items must be packed, labeled and declared to the carrier according to the regulations
Some common items could be a considered a dangerous good for transport, such as lithium-ion
batteries, aerosols, perfume etc.
The classification of a dangerous good is located on Section 14 of the SDS

50© Pistoia Alliance•

51© Pistoia Alliance

Dangerous Goods Incident 09Oct17

Shipping Activities
Regulators
Horizon scanning, encourage input to public consultations
Shipping and logistics,
Scitegrity

US Section 301© Pistoia Alliance

Monitoring progress of bills such
as SITSA

Monitoring legislativechanges e.g. Belgium,
52
Singapore© Pistoia Alliance

CSCS commercial tools

ExpediChem

54© Pistoia AlliancePart ofCompliance Hub for Drug Discovery

ExpediChem

Part ofCompliance Hub for Drug Discovery

▪
▪
▪
▪
▪
▪

digit level
Eliminate Tariff - Pharmaceutical and Chemical appendices covered
APIs - Automatically code all chemicals you have at the enterprise level
Search using your own internal chemical IDs
Place your own context sensitive overrides
Search by effect e.g “antibiotic” or “hormone”
Provide optional use and biologic effect activity information for
consideration (Drugs, Odiferous compounds, medicinal use etc)
55

© Pistoia Alliance▪ Covers UK, USA (incl schedule B), China, EU and Switzerland▪ Chapters 28 & 29 (Inorganic & Organics chemicals) typically to the full 10-

ExpediChem

56© Pistoia AlliancePart ofCompliance Hub for Drug Discovery

cHemTScHemTS is modular with Compliance Checker

CompliancecheckercHemTS

cHemTS

CH3
OH

O

O

O

INPUT
any chemical format(SMILES, names, CAS#...)

cHemTS

CH3
OH

O

O

O

INPUT
any chemical format(SMILES, names, CAS#...)

cHemTS

cHemTS

XLSX

CH3
OH

O

JSON

{i}

O

O

INPUT
any chemical format(SMILES, names, CAS#...)

cHemTSOUTPUT
HS codes related information

cHemTS – Countries covered

China
Switzerland
European Union
United Kingdom
India
Japan

United States
including Schedule BDrugs in the USA
Currently Identified by lookup in
Orange Book and Green Book
Compendium of approved
human and animal drug products
and therapeutic equivalents

WTO Pharma Agreement

As a result of the 1994 Agreement and the subsequent reviews,
participating members committed toeliminate customs duties and all other duties and charges
not only on all finished pharmaceutical products,
but also on over 7,000 pharmaceutical active ingredientsTAX

and chemical components used in pharmaceutical supply chains.

Exact structures

Salts/esters/hydrates

Intermediates

FREE

Compounds with extra info – Additional Classification
Classifications

Drugs

Medicinal use

PurityOdoriferous

Pesticides

Plasticizers

RubberPhotographic

and morecHemTSHow can I join?
A company must be a member of the Pistoia Alliance• Each company may send as many participants as they wish to
the meetings• You can join one or both expert communities• Details on how to join: cscs@pistoiaalliance.org© Pistoia Alliance•68© Pistoia Alliance

Meet us and see our posters

69© Pistoia Alliance

Questions