ORALPEACE PROJECT
Revolutionary Oral Care Productwill lead to Health Longevity andCreate Job Oppourtunity for the Disabled People

Trife Inc. CEO Daisuke Teshima

WHO IS THE MOST CLOSEST
TO YOUR HEART?

 Blessed with a disabled child.
 Worked at Uchida Yoko and Deloitte Tohmatsu Consulting Strategic
Marketing Team Found out that the hourly wage of the disabled is too low for theirindependence.
 National Average Wage is JPY 13,079 (US$ 130) per Month.
 In Yokohama, JPY 100 (US$ 1) per day in some cases.

 Difficulty in improving their income Sericious issue after parents are gone Below are the newspaper articles on my birthday in 2012

5 Yr Plan to double the disabled Salarylooking impossible to achieve

77 yr old mother and 44 yr old
son found left dead in the house First step is to start from what we can do Planning to Start up Organic Cosmetic Brand Venture andsubcontract to the Caring Facility of the Disabled
 Established NPO "Sell The Challenge" and supported to
manufacturing and marketing activity by the Caring Facility for 10years.

Finding Possibility of the Fusion ofWelfare and Business What is the purpose of my life ?
 What is my mission ?
 Who will take care of child after parents death ?
 Can the establishment of a strong company solve the problem ?

Starting from what we can do to create futures
for our most important ones Met with a Biotechnology Researcher Joint research with the University of Kyushu on Anti-Bacterial
Material of a Lactic Acid Bacterium "Bacteriocins".
 My father diagnosed as terminal cancer
 Unnecessarily weakened by incorrect prescription of antibotics
and disinfectant
 Encountered many oral care problems for the elderly patientsBIO x SOCIAL VENTURE

Increasing needs for Oral Care

 Aid for the elderly and disabled - US$ 93 billion
 Death caused by pulmonary aspiration pneumonia - 300 per day Announcement of Correlation between inproper oral care andalzehimer - Ministry of Health, Labor, and Welfare
 8020 Movement - 20 teeth at 80 years old

High Potential / Global Market
 Japanese Domestic Market Size - US$ 1.2 billion with Growth Rate of 3%
 Difficulty in effective oral care with traditional unswalloable product There is no high antibacterial swalloable product in the world other than
ORALPEACE Create new market with new innovation - ORALPEACE

Do not swallow

Oral Care with Water

US$ 1.2 billion expandingmarket

Only if there was a strong antibacterial
product you can swallow !!

Demand for Employment Opportunities
 Number of disabled in Japan - About 7.5 million, 1 in 12
 Aging society, the hollowing out in Japanese industry
 Decrease of the consumer population
 Increaes of pension for the disabled ?
 What will it be like in 10 years time ?

In order for the disabled who cannot leave his/her townbut need to make adequate living, we need to create
new business which can increase job opportunties allover JapanThrough creation of socially valuable
products and business, we will open doors
to new future for the disabled throughestablishment of a global company able tofind solutions to social concerns.

What is Oral Peace Project ?

MAIN TARGET

Elderly and disabled people who have difficulties in oralcare.
NEEDS

Need for daily oral care using safe and reliable incredients.
Easy, effective, and low cost.

ORIGINALITY

Supply of innovative oral care product at reasonableprice.
Create job opportunities for the desabled all over Japan

Bacteriocines from Lactic Acid Bacteria

 'Nisin' was first identified in the UK in 1928 from cheese,and was approved
as safe food preservation material in over 50 countries
 University of Michigan announced the effectivenes of bacteriocines against
oral cancer in 2012.
 It bought attention all over the world as future antibacterial material,
environmentally friendly, replacing traditional synthetic disinfectant andantibiotics.
 However, it contained salt and as such its' usage was limited for foodDevelopment of Natural Anti-Bacterial Agent''Neo-Nisin'' Industry-Academia collaboration research by University of Kyushu,
University of Kagoshima, National Center of Geriatrics and Gerontology
 Establishment of highly technical refinement technology of Nisin - tasteless,odorless, transparent, medically usable Effectiveness to gram-negative bacterial - obtained Patent

Outstanding Safety, Anti-Bacterial, Flavor - 'Neo-Nisin' Quick effectiveness agains cavities, periodontitis, bad breath, andpulmonary aspiration pneumonia
 Equivalent sterilizing properties to traditional synthetic disinfectant andantibiotics.
 Digested in stomach if swallowed, resolved in blood if entered into lungs
 Not achievable by previous 'Nisin'

36ths Dental Pharmacotherapy Conference【Result】

Experiment 1-1

Neo-Nisin ®(-)

Neo-Nisin®(+)

Neostelin Green®

Isodine®Gurgle
Solution# of Bacteria
(/ml)

添加回数

添加回数

添加回数

（=21）

添加回数

ORALPEACE now in the Market !

 2 products with refreshing flavor

 The first venture ever in the world to utilize bactliosin for medical
and cosmetical usage

Difference with the existing products

 100% natural ingredients - chemical free

 Death by pulmonary aspiration pneumonia
usually while asleep.
 Traditional sterilized products upset stomach ifswallowed Oralpeace can be used during sleep andreduces death risk

COMPETITIVE PRICE, CHEAPEST AMONG SIMILAR ITEMSHow do we create job opportunity through out Japan ?
There is limit to factory space availability, but room formarketing and sales activity is limitless

The disabled to promote socially useful andcompetitive products in their own regions

New business model - Disabled to market, sell, anddeliver products to the elderly in their own region.
Creating job opportunites for the disabled
New model of BOP business in Japan
Idea from BOP business in the developing countries

Care Faciity for the Disabled to become distibuting
agent

Using existing 5,000 distrubution care facilities all over Japan to instantly expand
business area
Raised wages without additional public / government expenditure.
No conflict with the opportunities for the non-disabled. Creating new job market.

Realize social participation through work

Jobs responding to social needs
Job circulation within the region

Able to Create job opportunities all over Japan高い利益率と収入
製品1本の販売で200~350円の収入
施設での小売で1本350円の収入 卸売では1本約200円
下請作業1工程1銭～、空き缶つぶし1個1円等の工賃
今までの仕事に組み合わせて簡単に取り組めるCLIENTSINJAPANThe first organic oralcare product inthe world with anti bacteria.

Authenticated organic productDisabled People's Institution inNiigata
Certified cosmetic manufacturing factory

Featured in NHK (Japanese NationalBroadcast) as the Outstanding Produce of
the New Era

1st Prize Winner ofJapan Venture Award 2015

New Oral Care Products for''Infants'', ''Outdoor extremes', ''Pets''- January 2015 -Business Expansion Plan Overseas Markering New market with 'Neo-Nisin' - disinfection products,
skin treatment, nasal cavity care, acne, anti-disasterproducts, ocular instillation, diapers etc.
 Insured medicine
 Become the US$1 billion pharmaceutical company

Company Goals
 Creating revolutionary product.
 Organize profitable business and socail works all inone
 Deliver strong message to the world from theworld's #1 aging society Become the global company of the new era

ORALPEACE Project Members

WE WILL CHANGE THE FUTURE
WE SHALL DO WHAT WE CAN DO

ITS NOT ABOUT WHAT WE CAN DO OR
WHAT WE CANNOT DOITS WHETHER WE DO IT OR NOTDELIVER STRONG MESSAGE TO THE
WORLD, THE NEW BUSINESS, FRIENDLY
FOR THE DISABLED AND ELDERLYPEOPLE

WHO IS THE MOST CLOSEST
TO YOUR HEART?

We welcome and look forward toworking with those who share thesame philosophy and motivation.

Thank you !!