CiRA Recruitment 2021

7

T-CiRA Program-Specific Researcher, Hotta Lab
Position
Work location

One Program-Specific Researcher (Specially Contracted Limited-Term Faculty)
T-CiRA Hotta Project (In vivo Genome Editing Therapy Project)
Center for iPS Cell Research and Application (CiRA), Shonan Branch
26-1, Muraoka-Higashi 2-chome. Fujisawa, Kanagawa, Postal code: 251-8555, Japan* 15-min Bus ride from JR Ofuna or Fujisawa station
https://www.shonan-health-innovation-park.com/en/access/Job description

With the Hotta Project in T-CiRA Program, we are conducting research and development of a novel
genome editing therapy for Duchenne muscular dystrophy. So far, we have developed various genedelivery techniques, such as LNP, AAV and VLP, and demonstrated the efficacy and safety using
patient’ iPS cells and animal models [Ref: Gee P et al., Nat Commun, 2020 | Morisaka H et al., NatCommun, 2019 | Li HL et al., Stem Cell Reports, 2015].
The T-CiRA project, which is a 10-year project started at the end of 2015 in collaboration with theCiRA and Takeda, will promote research and development for clinical application of innovative
therapeutics based on groundbreaking basic research. In this unique industry-university collaborative
project, we are conducting research aiming to develop a therapeutic method that has a scientific impact
and a benefit to patients. “Act for the Promotion of Science, Technology, and Innovation” will beapplied to this position.
For details of T-CiRA and our research, please visit the sites below:
https://www.takeda.com/what-we-do/t-cira/
http://www.cira.kyoto-u.ac.jp/hotta/en/

Job requirements

He/she has (or expects to have) a Ph.D. or equivalent professional achievements/capabilities inmedicine, dentistry, pharmacology, science, or engineering.
・Enthusiastic about the research and development of muscle disease treatment methods using
genome editing.
・Motivated to acquire and develop new experimental methods.
・Can work as a member of our team with researchers from academia, Takeda Pharmaceutical andrelated companies.
【Desired capabilities】
・Research experiences in the research field of DDS and cellular entry.
・Research experiences in the research field of CRISPR genome editing.
・Research experiences in the research field of muscular dystrophy model animals.

Contract period

Start day (negotiable) ~ March 31st, 2022 with a possibility of renewal until up to the end of theproject.
When the contract term has expired, the employment contract terminates. Renewal of the contract at
the expiration of a fixed-term employment contract is decided by comprehensive evaluation of yourwork performance, behavior, capabilities, etc. Working conditions may be changed at the renewal ofcontract. No matter how excellent your work performance, behavior, and capabilities have been, there
are cases in which the contract is not renewed on account of unavoidable reasons, such as change offinancial status, or loss of the job contents specified above due to reassignment of your lab’s principal
investigator or reorganizations.
Probational

6 months

periodWorking

Kyoto University Program-Specific Researcher (full-time, annual salary system)

conditions

・ Salaries are determined based on the Kyoto University standards depending on capabilities andbackgrounds.
・ Annual salary includes various allowances.
・ Discretionary work system for specialist staff (38 hours and 45 minutes/week, 7 hours and 45
minutes/day)・ Holidays: Saturdays, Sundays, national holidays, summer break, year-end and new-year break,the anniversary of foundation holiday, and paid holidays
・ MEXT Mutual Association of Health Insurance, employee pension insurance, industrial
accident compensation insurance, and employment insurance

Deadline for

We will close the recruitment when the position is filled.

application
Documents to besubmitted

Please submit the following documents:
1. Curriculum vitae (Form 1)
Please write names and contact information of two referees who can evaluate you. Please write
the email address and telephone number by which we can unfailingly contact you in thedesignated space.
2.

List of research achievements or professional achievements (publications, presentations, acquired

research funds, patents, etc.) (Form 2)
3. Outlines of research progress and research results in the past (Form 3)※Please use the Forms 1 through 3 for the documents required above. You will find the Forms fordownloading at: http://www.cira.kyoto-u.ac.jp/e/employment/img/doc/Application_Forms.zip
If you do not find appropriate items in the Forms, please add items to the Forms as needed.
※Additional information may be requested in the process of screening.
Contact

Please send the application documents to the following address by postal mail or e-mail.
Hotta Lab, Center for iPS Cell Research and Application, Kyoto University
53 Kawahara-cho, Shogoin, Sakyo-ku, Kyoto 606-8507 JAPANE-mail : akitsu.hotta*cira.kyoto-u.ac.jp（Please change “*” to “＠”.）・Please be sure to write “Application documents for Program-Specific Researcher of Hotta Lab” on
the envelope or in the subject line of the e-mail.
・If you make inquiries about job specifications or working conditions, please contact Hottamentioning in the subject line as: “Re: Recruitment of Program-Specific Researcher of Hotta Lab”

Selection method

An interview will follow the screening of application documents. Those who have passed thescreening will be informed of the date and time of the interview via e-mail or in writing, and may berequested to give a lecture on the research or professional achievements at the interview. (Interviewees
will bear their transportation and accommodation expenses for the interview.)
Results will be informed via e-mail or in writing as soon as the decision is made.

Gender equality
Others

Kyoto University is promoting the gender equality. Woman researchers are encouraged to apply.
Submitted documents shall be used just for the selection, and never be disclosed, transferred, or lentto the third party without due reasons.
Please be advised that submitted documents shall not be returned.
Kyoto University is working to prevent passive smoking, by prohibiting indoor smoking on all
campuses and also outside smoking except in designated areas.

We are looking for a postdoctoral fellow who is interested in Academia-Industry collaboration
to develop genome editing therapy for muscular dystrophy.
We are looking forward to your application!