Table 2. Target diseases of the Infectious Diseases Control Law revised on April 1, 2007
(Reportable infectious diseases of categories I to V
under the National Epidemiological Surveillance of Infectious Diseases)
1. Target diseases to be notified all cases by all physicians
Category I (to be notified promptly after diagnosis)
Crimean-Congo hemorrhagic fever*, Ebola hemorrhagic fever*, Lassa fever*, Marburg disease*, Plague*,Smallpox*, South American hemorrhagic fever*Category II (to be notified promptly after diagnosis)
Acute poliomyelitis*, Diphtheria*, Severe Acute Respiratory Syndrome (due to SARS coronavirus)*, Tuberculosis*
Category III (to be notified promptly after diagnosis)
Cholera*, Enterohemorrhagic Escherichia coli infection*, Paratyphoid fever*, Shigellosis*, Typhoid fever*Category IV (to be notified promptly after diagnosis)
Anthrax*, Avian influenza virus infection*, Botulism*, Brucellosis*, Coccidioidomycosis*, Dengue fever*,Eastern equine encephalitis*, Echinococcosis*, Epidemic typhus*, Glanders*, Hantavirus pulmonary syndrome*,Hemorrhagic fever with renal syndrome*, Hendra virus infection*, Hepatitis A, Hepatitis E*,
Herpes B virus infection*, Japanese encephalitis*, Japanese spotted fever*, Kyasanur Forest disease*,
Legionellosis*, Leptospirosis*, Lyme disease*, Lyssavirus infection (excluding rabies)*, Malaria, Melioidosis*,Monkeypox*, Nipah virus infection*, Omsk hemorrhagic fever*, Psittacosis*, Q fever*, Rabies*, Relapsing fever*,
Rift Valley fever*, Rocky Mountain spotted fever*, Scrub typhus（Tsutsugamushi disease)*,Tick-borne encephalitis*, Tularemia*, Venezuelan equine encephalitis*,West Nile fever (including West Nile encephalitis)* , Western equine encephalitis*, Yellow fever*Category V (to be notified within 7 days after diagnosis)
Acquired immunodeficiency syndrome*, Amebiasis*, Acute encephalitis (excluding Eastern equine encephalitis,Japanese encephalitis, Rift Valley fever, Tick-borne encephalitis, Venezuelan equine encephalitis, West Nileencephalitis and Western equine encephalitis)*, Congenital rubella syndrome*, Creutzfeldt-Jakob disease*,
Cryptosporidiosis, Giardiasis, Meningococcal meningitis*, Severe invasive streptococcal infections(Streptococcal toxic shock-like syndrome)*, Syphilis, Tetanus*,
Vancomycin-resistant Enterococcus infection*, Vancomycin-resistant Staphylococcus aureus infection*,
Viral hepatitis (excluding hepatitis A and E)
Designated disease (to be notified promptly after diagnosis)
Influenza (H5N1)
2. Target diseases to be reported by the sentinel clinics and hospitals
Category V<Influenza sentinel> (weekly report)
Influenza (excluding avian influenza virus infection)*<Pediatric disease sentinel> (weekly report)
Chickenpox, Erythema infectiosum, Exanthem subitum, Group A streptococcal pharyngitis*,Hand, foot and mouth disease*, Herpangina*, Infectious gastroenteritis*, Measles (excluding adult)*, Mumps*,
Pertussis*, Pharyngoconjunctival fever*, Respiratory syncytial virus infection*, Rubella<Eye disease sentinel> (weekly report)
Acute hemorrhagic conjunctivitis*, Epidemic keratoconjunctivitis*<Sexually transmitted disease (STD) sentinel> (monthly report)
Condyloma acuminatum, Genital chlamydial infection, Genital herpes, Gonorrhea<Target diseases at sentinel hospital>(weekly report)
Aseptic meningitis*, Bacterial meningitis*, Chlamydial pneumonia (excluding psittacosis), Measles in adults*,
Mycoplasmal pneumonia(monthly report)
Methicillin-resistant Staphylococcus aureus infection, Multi-drug-resistant Pseudomonas aeruginosa infection,
Penicillin-resistant Streptococcus pneumoniae infection
Target disease of syndromic surveillance designated by the government ordinance<Syndromic surveillance sentinel> (to be reported promptly after diagnosis)
Unknown fever (≥38 °C) and respiratory symptom, Unknown fever and rash/vesicle
3. Target disease of active epidemiological surveillance to be reported through on-line system
Designated disease
Influenza (H5N1)
An underline shows the disease added or changed in this revision.
*Target disease of infectious agent surveillance