esCCO Information vol.

The Next Generation of
Non-Invasive
Hemodynamics Monitoring

NIHON KOHDEN is redefining Quality of

Nihon Kohden researcher Takuo Aoyagi

Care with new non-invasive technologies

in 1974, the pulse wave has become

like PWTT（pulse wave transit time）andthe most commonly used vital signal

esCCO（estimated continuous cardiac

in clinical practice. The pulse wave cano u t p u t）b y i n t r o d u c i n g v o l u m e t r i cprovide time-related information suchinformation to all care levels.

as intravascular pressure transmission as
well as information about arterial blood

Since the invention of pulse oximetry by

A high correlation between
PWTT and stroke volume has
been demonstrated in animalstudies 1）. Ishihara et al. also
reported that continuous
cardiac output estimated with
PWTT and heart rate is highly
correlated with cardiac output
determined by thermodilution technique2）.
In 2009, a multi-center study at seven
facilities verified the effectiveness of esCCO
as a practical application3）.

volume change.

2

esCCO is available
on following
NIHON KOHDEN
patient monitors

esCCO Information vol.2

Redefining Quality of Care withor compromised hemodynamic status
in the ICU and recovery room. With thisnon-invasive cardiovascular monitoring,
hemodynamic and cardiovascular trends
will be available on standard monitors.
esCCO can be also used as criteria todetermine if the patient can be discharged
from post-operative care and continuousmonitoring unit. Monitoring of cardiac
and vascular function by using this noninvasive method may assist physicians to
NIHON KOHDEN is one ofJapan’s leading players
in medical technology
development andmanufacturing, andhas subsidiaries andrepresentative offices
worldwide.
“Fighting Disease withElectronics” – our corporate
philosophy – reflects thehigh standards we haveset ourselves in combating
disease by developing
medical systems, contributing
to higher quality of life forpatients. Our product range
focuses on patient monitoring,cardiology（ECG equipmentand defibrillators）as well asneurology（EEG, EMG and EP）.

Emergency medicine

see if the patient is recovered sufficiently

The dynamic parameters of cardiac

general ward.

to be discharged from special care unit tofunction and the vascular system areimportant in the evaluation of patientswith systemic inflammatory condition whoOperation roompresent to the emergency department.

esCCO can be extremely useful for

Patients are evaluated for admission

anesthesia management for patient withto the standard care unit, continuous

cardiac disease during surgery. Monitors

monitoring unit or ICU, based on theirequipped with esCCO provide usable

clinical condition such as inflammatory,

information continuously and non-sepsis, and shock. esCCO non-invasivelyinvasively and might bring a dynamic

provides hemodynamic information thatchange to the conventional anesthesia

is useful in this patient evaluation process.

procedure.

The display of esCCO can assist ER staff to

Non-invasive circulatory monitoring using

see a patientʼs condition more effectively,

esCCO could become a new standard

and assist physicians to recognize earlier if

for patient monitoring in anesthesia

the patient has a serious condition such asmanagement during various surgeries,

myocarditis.

including cardiac, circulatory and thoracic
surgery.

References1）Sugo Y, Ukawa T, Takeda S,Ishihara H, Kazama T, Takeda Z.
A Novel Continuous Cardiac
Output Monitor Based on Pulse
Wave Transit Time. Conf Proc
IEEE Eng Med Biol Soc. 2010;2010; 2853-62）Ishihara et al, A new non-invasive
continuous cardiac output
trend solely utilizing routine
cardiovascular monitors. J Clin
Monit, 2004 Dec; 18, 313-320
3）T. Yamada, Y. Sugo, J. Takeda,esCCO ResearchTeam.
Verification of a non-invasive
continuous cardiac output
measurement method basedon the pulse-contour analysis
combined with pulse wavetransit time. Eur J Anaesthesiol
2010; 27（Suppl 47）:3AP5-98753 SP61-002A ’16. 7. CLB.A

ICU and recovery room
esCCO can be useful as a monitoring
tool to follow up patients with unstable