7th Asia-Pacific Conference on Plasma Physics, 12-17 November, 2023,
Port Messe Nagoya, Japan

Simulation Analysis for Detection of various Biomolecules in a Double Gate PlasmaAssisted Carbon Nanotube Field Effect Transistor (DG-CNFET)
Bhargavi Sharma1, Nagendra Singh1, Jyoti Upadhyaya1 and Mansha Kansal2
1

Department of Biotechnology, Gautam Buddha University, Greater Noida, UP, India

2

Department of Applied Physics, Delhi Technological University, Bawana Road, Delhi-110085, Indiae-mail: bhargavisharma030@gmail.com (Bhargavi Sharma) and kansal.mansha@gmail.com (ManshaKansal)

Abstract
These days, practically every field uses abiosensor in some capacity. Biosensors
are cutting-edge analytical tools thatcombine transducers and biologicalrecognition components to identify andmeasure certain molecules or analytes incomplex samples. These advanced
devices interact with the target analyte ofinterest using the inherent sensitivity andspecificity of biological elements, such asenzymes, proteins, antibodies, nucleicacids, or entire cells. The biologicalrecognition element and the analyteinteract to produce a quantifiable signal,
which is subsequently transformed into
useable data by the biosensor's transducercomponent.
Medicaldiagnostics,environmental monitoring, food safety,biotechnology,
andpharmaceuticalresearch are just a few of the industries
where biosensors are used. Biosensors are
employed in the medical industry todiagnose illnesses, keep track ofbiomarkers, and monitor vital signs inreal time. They have made a substantial
contribution to personalised medicine byproviding quick and precise results that
help with early detection and treatment
choices. This study suggests a Double
Gate Plasma-Assisted (DG-CNFET)
based biosensor for the detection ofvarious biomolecules. The impact ofdifferent biomolecule species (e.g.,
Uricase, Protein, APTES, ChOX,Streptavidin and Biotin) on the device's
performance metrics has been studied.
With the addition of biomolecules to thenanocavity, it has been noted that thedrain current increases significantly.
Similarly, biomolecules can also be used
to obtain the change in transconductance.

We analyse the various electricalproperties of proposed device e.g.,transconductance, output conductanceand cutoff frequency at different plasmaassisted channel radius. In addition to theexcellent power performance of DG
Plasma-Assisted CNFET, this device has
demonstrated good sensing and can beeffectively
usedforbiosensing
applications.

References
1. R. Narang, M. Saxena, and M. Gupta,
Investigation of dielectric modulated (DM) double
gate (DG) junctionless MOSFETs for application asa biosensors, Superlatt. Microstruct. 85, 557(2015).
2. C. Vu, Field-effect transistor biosensors forbiomedical applications: recent advances and future
prospects. Sensors 19, 4214 (2019).
3. Y. Chen et al., Field-effect transistor biosensor for
rapid detection of Ebola antigen. Sci. Rep. 7(1), 1–8 (2017).
4. I.M. Hyungsoon, X.-J. Huang, B. Gu, Y.-K. Choi,
A dielectric modulated field-effect transistor forbiosensing. Nat. Nanotechnol. 2, 430–434 (2007).
5. M. Kansal, S.C. Sharma, Plasma-basednanoarchitectonics for vertically aligned dual-metal
carbon nanotube field-effect transistor (VADMCNFET) device: effect of plasma parameters ontransistor properties. Appl. Phys. A 128, 28 (2022).
https://doi.org/10.1007/s00339-021-05096-2
6. M. Kansal, S.C. Sharma, Performance Evaluation& Linearity Distortion Analysis for Plasma- Assisted
Dual-Material Carbon Nanotube Field EffectTransistor with a SiO2-HfO2 Stacked Gate-Oxide
Structure (DM-SGCNFET). Silicon 14, 12381–12391(2022).
https://doi.org/10.1007/s12633-02201930-1