＜生命医科学域＞

8

神経内分泌学
a）英文論文1. Lee MC, Okamoto M, Liu YF, Inoue K, Matsui T, Nogami H, Soya H. Voluntary resistancerunning with short distance enhances spatial memory related to hippocampal BDNF signaling. J
Appl Physiol 113(8):1260-1266, 2012
2. Nogami H, Soya H, Hiraoka Y, Aiso S, Hisano S. Epidermal growth factor-activated extracellularsignal-regulated kinase suppresses growth hormone expression and stimulates proliferation in MtT/
E cells. J Neuroendocrinol 24(2):357-365, 2012
3. Ozaki S, Hisano S, Iwamoto Y. Potency of animal models in Kansei Engineering - A basic
approach from neuroscience. Kansei Engineering International Journal 11:127-132, 2012
4. Sanada K, Sugimoto K, Shutoh F, Hisano S. Lemon odor reduces stress-induced neuronal activationin the emotion expression system: an animal model study. Kansei Engineering International
Journal 11:115-120,2012
5. Yoshida S, Hisano S. Vesicular glutamate transporter 2 expression in the rat pineal gland: detailed
analysis of expression pattern and regulatory mechanism. Kansei Engineering International
Journal 11:133-137, 2012

解剖学・発生学	
 a）英文論文1. Avci HX, Lebrun C, Wehrlé R, Doulazmi M, Chatonnet F, Morel MP, Ema M, Vodjdani G, Sotelo
C, Flamant F, Dusart I. Thyroid hormone triggers the developmental loss of axonal regenerative
capacity via thyroid hormone receptor α1 and krüppel-like factor 9 in Purkinje cells. Proc Natl
Acad Sci U S A 109(35):14206-14211, 2012
2. Fujita A, Yoh K, Shimohata H, Morito N, Ojima M, Okamura M, Takahashi S, Yamagata K. A
novel diabetes mellitus mouse model, MafA-deficient and beta cell-specific MAFK-overexpressing
hybrid transgenic mice, developed severe diabetic nephropathy and improved with TCV-116(candesartan cilexetil) treatment. Exp Anim 61(1):49-57, 2012
3. Inoue A, Matsumoto I, Tanaka Y, Umeda N, Tanaka Y, Mihara M, Takahashi S, Sumida T. Murine
tumor necrosis factor alpha-induced adipose-related protein (tumor necrosis factor alpha-induced
protein 9) deficiency leads to arthritis via interleukin-6 overproduction with enhanced NF-κB,
STAT-3signaling,anddysregulated

apoptosis

ofmacrophages.

ArthritisRheum

64(12):3877-3885, 2012
4. Kondo Y, Iizuka M, Wakamatsu E, Yao Z, Tahara M, Tsuboi H, Sugihara M, Hayashi T, Yoh K,
Takahashi S, Matsumoto I, Sumida T. Overexpression of T-bet gene regulates murine autoimmune
arthritis. Arthritis Rheum 64(1):162-172, 2012
5. Lebrun C, Avci HX, Wehrlé R, Doulazmi M, Jaudon F, Morel MP, Rivals I, Ema M, Schmidt S,
9Sotelo C, Vodjdani G, Dusart I. Klf9 is necessary and sufficient for Purkinje cell survival inorganotypic culture. Mol Cell Neurosci 54:9-21, 2013, doi: 10.1016/j.mcn.2012.11.010., 2012
6. Matsumoto K, Azami T, Otsu A, Takase H, Ishitobi H, Tanaka J, Miwa Y, Takahashi S, Ema M.
Study of normal and pathological blood vessel morphogenesis in Flt1-tdsRed BAC Tg mice.
Genesis 50(7):561-571, 2012
7. Nagamine S, Tamba M, Ishimine H, Araki K, Shiomi K, Okada T, Ohto T, Kunita S, Takahashi S,
Wismans RG, van Kuppevelt TH, Masu M, Keino-Masu K. Organ-specific sulfation patterns ofheparan sulfate generated by extracellular sulfatases Sulf1 and Sulf2 in mice. J Biol Chem
287(12):9579-9590, 2012
8. Oishi H, Itoh S, Matsumoto K, Ishitobi H, Suzuki R, Ema M, Kojima T, Uchida K, Kato M, Miyata
T, Takahashi S. Delayed cutaneous wound healing in Fam129b/Minerva-deficient mice. J Biochem
152(6):549-555, 2012
9. Sano K, Katsuta O, Shirae S, Kubota Y, Ema M, Suda T, Nakamura M, Hirashima M. Flt1 and Flk1
mediate regulation of intraocular pressure and their double heterozygosity causes the buphthalmia
in mice. Biochem Biophys Res Commun 420(2):422-427, 2012
10. Sekiguchi Y, Owada J, Oishi H, Katsumata T, Ikeda K, Kudo T, Takahashi S. Noninvasive
monitoring of β-cell mass and fetal β-cell genesis in mice using bioluminescence imaging. Exp
Anim 61(4):445-451, 2012
11. Takase H, Matsumoto K, Yamadera R, Kubota Y, Otsu A, Suzuki R, Ishitobi H, Mochizuki H,
Kojima T, Takano S, Uchida K, Takahashi S, Ema M. Genome-wide identification of endothelial
cell-enriched genes in the mouse embryo. Blood 120(4):914-923, 2012
12. Tojo M, Takebe A, Takahashi S, Tanaka K, Imamura T, Miyazono K, Chiba T. Smad7-deficient
mice show growth retardation with reduced viability. J Biochem 151(6):621-631, 2012
13. Yoh K, Morito N, Ojima M, Shibuya K, Yamashita Y, Morishima Y, Ishii Y, Kusakabe M,
Nishikii H, Fujita A, Matsunaga E, Okamura M, Hamada M, Suto A, Nakajima H, Shibuya A,
Yamagata K, Takahashi S. Overexpression of RORγt under control of the CD2 promoter induces
polyclonal plasmacytosis and autoantibody production in transgenic mice. Eur J Immunol
42(8):1999-2009, 2012

神経生物学	
 a)英文論文	 1. Ishikawa C, Shiga T. Massage changes babies’ body, brain and behavior. Kansei Engineering
International J 11:109-114, 2012
2. Iwakura T, Sakoh M, Tsutiya A, Yamashita N, Ohtani A, Tsuda MC, Ogawa S, Tsukahara S,
Nishihara M, Shiga T, Goshima Y, Kato T, Ohtani-Kaneko R. Collapsin response mediator protein
4 affects the number of tyrosine hydroxylase-immunoreactive neurons in the sexually dimorphic
nucleus in female mice. Dev Neurobiol doi: 10.1002/dneu.22076., 201210

3. Kobayashi A, Senzaki K, Ozaki S, Yoshikawa M, Shiga T. Runx1 promotes neuronal differentiationin dorsal root ganglion. Mol Cell Neurosci 49(1):23-31, 2012
4. Li F, Ohtani A, Senzaki K, Shiga T. Receptor-dependent regulation of dendrite formation ofnoradrenaline and dopamine in non-GABAergic cerebral cortical neurons. Dev Neurobiol doi:
10.1002/dneu.22065., 2012
5. Masuda T, Sakuma C, Taniguchi M, Kanemoto A, Yoshizawa M, Satomi K, Tanaka H, Takeuchi K,
Ueda S, Yaginuma H, Shiga T. Development of the dorsal ramus of the spinal nerve in the chickembryo: a close relationship between development and expression of guidance cues. Brain Res
1480:30-40, 2012
6. Yamamuro T, Hori M, Nakagawa Y, Hayashi T, Sakamoto S, Ohnishi J, Takeuchi S, Mihara Y,
Shiga T, Murakami K, Urayama O. Tickling stimulation causes the up-regulation of the kallikreinfamily in the submandibular gland of the rat. Behav Brain Res doi: 10.1016/j.bbr.2012.09.001.,
2012	
 
	
 
	
 

診断病理学	
 a)英文論文	 1. Kawamura T, Usui J, Kaseda K, Takada K, Ebihara I, Ishizu T, Iitsuka T, Sakai K, Takemura K,
Kobayashi M, Koyama A, Kanemoto K, Sumazaki R, Uesugi N, Noguchi M, Nagata M, Suka M,
Yamagata K. Primary membranoproliferative glomerulonephritis on the decline: decreased ratefrom the 1970s to the 2000s in Japan. Clin Exp Nephrol doi: 10.1007/s10157-012-0690-7.，2012
2. Kondo Y, Iijima T, Noguchi M. Evaluation of immunohistochemical staining using whole-slide
imaging for HER2 scoring of breast cancer in comparison with real glass slides. Pathol Int
62(9):592-599, 2012
3. Nagata C, Kobayashi H, Sakata A, Satomi K, Minami Y, Morishita Y, Ohara R, Yoshikawa H, Arai
Y, Nishida M, Noguchi M. Increased expression of OCIA domain containing 2 during stepwise
progression of ovarian mucinous tumor. Pathol Int 62(7):471-476, 2012
4. Shiba-Ishii A, Noguchi M. Aberrant stratifin overexpression is regulated by tumor-associated CpG
demethylation in lung adenocarcinoma. Am J Pathol 180(4):1653-1662, 2012
5. Tachibana K, Minami Y, Shiba-Ishii A, Kano J, Nakazato Y, Sato Y, Goya T, Noguchi M.
Abnormality of the hepatocyte growth factor/MET pathway in pulmonary adenocarcinogenesis.
Lung Cancer 75(2):181-188, 2012
6. Watanabe M, Tamaoka A, Morishita Y, Noguchi M. Cilnidipine Lowers Plasma Leptin of Patientswith Obese Hypertension Associated with Cerebrovascular Disorder. Open Access Scientific
Reports 1(11):529-602, 2012b）英文以外の論文

111. 木村友, 及川剛, 池田篤, 吉野喬, 末富崇, 宮崎淳, 島居徹, 橋本孝, 杉田真, 野口雅之, 西山博. 陰茎原発紡錘形細胞肉腫の 1 例. 泌尿器科紀要 58(6):299-305, 2012
2. 佐藤泰樹, 南優子, 野口雅之. 肺癌の新しい病理組織分類̶その意義と意図. 医学のあゆみ
240(13):1041-1044, 2012
3. 竹内朋代, 森下由紀雄, 野口雅之. バイオバンク構築における病理の役割【共同研究の起点として機能する我が国のバイオバンクの実例】大学病院を中心とした地域レベルのバンキングシス
テム構築の試み. 病理と臨床 30(6):646-653, 2012
4. 野口雅之. 肺癌の病理̶特に肺腺癌の分類の現状について̶. 肺癌 52(3):339-345, 2012
5. 野口雅之. 【肺腺癌の分類】肺腺癌新国際分類（IASLC,ATS,ERS）の概要.肺腺癌の診断と治療
̶新しい分類と臨床治療の変化̶. 病理と臨床 30(5):484-487, 2012
6. 南優子, 野口雅之. 【肺腺癌の分類】上皮内腺癌と微少浸潤性腺癌. 肺腺癌の診断と治療̶新
しい分類と臨床治療の変化̶. 病理と臨床 30(5):488-491, 2012

実験病理学	
 a)英文論文	 1. Ido K, Ohwada T, Yasutomi E, Yoshinaga T, Arai T, Kato M and Sawada K. Screening quality forCa(2+)-activated potassium channel in IonWorks Quattro is greatly improved by using
BAPTA-AM and ionomycin. J Pharmacol Toxicol Methods. doi: 10.1016/j.vascn.2012.10.005. ,2012
2. Itoh F, Itoh S, Adachi T, Ichikawa K, Matsumura Y, Takagi T, Festing M, Watanabe T, Weinstein
M, Karlsson S, Kato M. Smad2/Smad3 in endothelium is indispensable for vascular stability via
S1PR1 and N-cadherin expressions. Blood 119(22):5320-5328, 2012
3. Oishi H, Itoh S, Matsumoto K, Ishitobi H, Suzuki R, Ema M, Kojima T, Uchida K, Kato M, Miyata
T, Takahashi S. Delayed cutaneous wound healing in Fam129b/Minerva-deficient mice. J Biochem
152(6):549-555, 2012

腎・血管病理学	
 a)英文論文1. Furuya K, Yasumori K, Takeo S, Sakino I, Uesugi N, Momosaki S, Muranaka T. Lung CT: Part 1,
Mimickers of lung cancer--spectrum of CT findings with pathologic correlation. AJR Am J
Roentgenol 199(4):W454-463, 2012
2. Iijima K, Someya T, Ito S, Nozu K, Nakanishi K, Matsuoka K, Ohashi H, Nagata M, Kamei K,
Sasaki S. Focal segmental glomerulosclerosis in patients with complete deletion of one WT1 allele.
Pediatrics 129(6):e1621-1625, 2012
3. Kawamura T, Usui J, Kaseda K, Takada K, Ebihara I, Ishizu T, Iitsuka T, Sakai K, Takemura K,
12

Kobayashi M, Koyama A, Kanemoto K, Sumazaki R, Uesugi N, Noguchi M, Nagata M, Suka M,
Yamagata K. Primary membranoproliferative glomerulonephritis on the decline: decreased ratefrom the 1970s to the 2000s in Japan. Clin Exp Nephrol doi: 10.1007/s10157-012-0690-7., 2012
4. Mizushima I, Yamada K, Fujii H, Inoue D, Umehara H, Yamagishi M, Yamaguchi Y, Nagata M,
Matsumura M, Kawano M. Clinical and histological changes associated with corticosteroid therapy
in IgG4-related tubulointerstitial nephritis. Mod Rheumatol 22(6):859-870, 2012
5. Taneda S, Honda K, Uchida K, Nitta K, Yumura W, Oda H, Nagata M. Histological heterogeneityof glomerular segmental lesions in focal segmental glomerulosclerosis. Int Urol Nephrol
44(1):183-196, 2012
6. Ueno T, Takeda K, Nagata M. Remission of proteinuria and preservation of renal function inpatients with renal AA amyloidosis secondary to rheumatoid arthritis. Nephrol Dial Transplant27(2):633-639, 2012
7. Yamaguchi Y, Kanetsuna Y, Honda K, Yamanaka N, Kawano M, Nagata M, Japanese study groupon IgG4-related nephropathy. Characteristic tubulointerstitial nephritis in IgG4-related disease.
Hum Pathol 43(4):536-549, 2012
8. Yokoyama H, Sugiyama H, Sato H, Taguchi T, Nagata M, Matsuo S, Makino H, Watanabe T, Saito
T, Kiyohara Y, Nishi S, Iida H, Morozumi K, Fukatsu A, Sasaki T, Tsuruya K, Kohda Y, Higuchi
M, Kiyomoto H, Goto S, Hattori M, Hataya H, Kagami S, Yoshikawa N, Fukasawa Y, Ueda Y,
Kitamura H, Shimizu A, Oka K, Nakagawa N, Ito T, Uchida S, Furuichi K, Nakaya I, Umemura S,
Hiromura K, Yoshimura M, Hirawa N, Shigematsu T, Fukagawa M, Hiramatsu M, Terada Y,
Uemura O, Kawata T, Matsunaga A, Kuroki A, Mori Y, Mitsuiki K, Yoshida H. Renal disease in
the elderly and the very elderly Japanese: analysis of the Japan Renal Biopsy Registry (J-RBR).
Clin Exp Nephrol 16(6):903-920, 2012b）英文以外の論文
1. 上杉憲子. 【腎臓症候群(第 2 版)上-その他の腎臓疾患を含めて-】 先天性・遺伝性腎疾患 遺伝性腎疾患 家族性 LCAT 欠損症. 日本臨床 別冊(腎臓症候群(上)):323-327, 2012
2. 上杉憲子. フィブロネクチン腎症. 日本臨床 別冊(腎臓症候群 (上)):33-37, 2012
3. 小林凡子, 長田道夫. 【ネフローゼ症候群治療の最前線】 ネフローゼ症候群とポドサイトパチー.
腎と透析 72(6):803-809, 2012
4. 長田道夫, 山本格. 特集 2 研究手法の進歩がもたらした腎臓病学の新たな知見：序. 腎と透析
72:199-201, 2012
5. 山村なつみ, 長田道夫. 【周産期と腎】 腎臓の発達と胎内環境. 周産期医学 42(9):1153-1156,
2012

	
 

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システム神経科学	
 a）英文論文1. Iwamoto Y, Umetsu D, Ozaki S. Evaluation of driver-vehicle matching using neck muscle activity
and vehicle dynamics. Kansei Engineering International Journal 11(3):147-154, 2012
2. Mizuhiki T, Inaba K, Setogawa T, Toda K, Ozaki S, Shidara M. The influence of passband
limitation on the waveform of extracellular action potential. Neurosci Res 72(3):214-220, 2012
3. Mizuhiki T, Richmond BJ, Shidara M. Encoding of reward expectation by monkey anterior insular
neurons. J Neurophysiol 107(11):2996-3007, 2012
4. Ohyama K, Sugase-Miyamoto Y, Matsumoto N, Shidara M, Sato C. Stimulus-related activity
during conditional associations in monkey perirhinal cortex neurons depends on upcoming reward
outcome. J Neurosci 32(48):17407-17419, 2012
5. Ozaki S, Hisano S, Iwamoto Y. Potency of animal models in KANSEI engineering: a basic
approach from neuroscience. Kansei Engineering International Journal 11(3):127-132, 2012
6. Toda K, Sugase-Miyamoto Y, Mizuhiki T, Inaba K, Richmond BJ, Shidara M. Differential
encoding of factors influencing predicted reward value in monkey rostral anterior cingulate cortex.
PLoS One 7(1):e30190, 2012d）英文以外の著書
1. 尾崎繁. 第４章. 筋収縮; "はじめの一歩のイラスト生理学 (改訂第２版)” (編集 照井直人), 羊
土社 (東京) 2012; pp39-44
2. 尾崎繁. 第９章. 運動; "はじめの一歩のイラスト生理学 (改訂第２版)” (編集 照井直人), 羊土社 (東京) 2012; pp79-88

神経生理学a)英文論文	 1. Iwamoto Y, Umetsu D, Ozaki S. Evaluation of driver-vehicle matching using neck muscle activity
and vehicle dynamics. Kansei Engineering International Journal 11(3):147-154, 2012
2. Ozaki S, Hisano S, Iwamoto Y. Potency of animal models in KANSEI engineering: a basic
approach from neuroscience. Kansei Engineering International Journal 11(3):127-132, 2012

分子細胞生物学a)英文論文	 1. Yamaguchi Y, Naiki T, Irie K. Stau1 regulates Dvl2 expression during myoblast differentiation.
Biochem Biophys Res Commun 417(1):427-432, 201214

遺伝子制御学	 a）英文論文1. Nishimura T, Kaneko S, Kawana-Tachikawa A, Tajima Y, Goto H, Zhu D, Nakayama-Hosoya K,
Iriguchi S, Uemura Y, Shimizu T, Takayama N, Yamada D, Nishimura K, Ohtaka M, Watanabe N,
Takahashi S, Iwamoto A, Koseki H, Nakanishi M, Eto K, Nakauchi H. Generation of rejuvenatedantigen-specific T cells by reprogramming to pluripotency and redifferentiation. Cell Stem Cell
doi: 10.1016/j.stem.2012.11.002., 2012

診断生化学	
 a)英文論文1. Fujimoto Y, Nakagawa Y, Shingyouchi A, Tokushige N, Nakanishi N, Satoh A, Matsuzaka T, Ishii
KA, Iwasaki H, Kobayashi K, Yatoh S, Suzuki H, Yahagi N, Urayama O, Yamada N, Shimano H.
Dicer has a crucial role in the early stage of adipocyte differentiation, but not in lipid synthesis, in
3T3-L1 cells. Biochem Biophys Res Commun 420(4):931-936, 2012
2. Iwasaki H, Naka A, Iida KT, Nakagawa Y, Matsuzaka T, Ishii KA, Kobayashi K, Takahashi A,
Yatoh S, Yahagi N, Sone H, Suzuki H, Yamada N, Shimano H. TFE3 regulates muscle metabolic
gene expression, increases glycogen stores, and enhances insulin sensitivity in mice. Am J Physiol
Endocrinol Metab 302(7):E896-902, 2012
3. Lerner AG, Upton JP, Praveen PV, Ghosh R, Nakagawa Y, Igbaria A, Shen S, Nguyen V, Backes
BJ, Heiman M, Heintz N, Greengard P, Hui S, Tang Q, Trusina A, Oakes SA, Papa FR. IRE1αinduces thioredoxin-interacting protein to activate the NLRP3 inflammasome and promote
programmed cell death under irremediable ER stress. Cell Metab 16(2):250-264, 2012
4. Matsuzaka T, Atsumi A, Matsumori R, Nie T, Shinozaki H, Suzuki-Kemuriyama N, Kuba M,
Nakagawa Y, Ishii K, Shimada M, Kobayashi K, Yatoh S, Takahashi A, Takekoshi K, Sone H,
Yahagi N, Suzuki H, Murata S, Nakamuta M, Yamada N, Shimano H. Elovl6 promotes
nonalcoholic steatohepatitis in mice and humans. Hepatology 56 (6):2199-2208, 2012
5. Naka A, Iida KT, Nakagawa Y, Iwasaki H, Takeuchi Y, Satoh A, Matsuzaka T, Ishii KA,
Kobayashi K, Yatoh S, Shimada M, Yahagi N, Suzuki H, Sone H, Yamada N, Shimano H. TFE3
inhibits myoblast differentiation in C2C12 cells via down-regulating gene expression of myogenin.
Biochem Biophys Res Commun doi: 10.1016/j.bbrc.2012.11.094., 2012
6. Yamamuro T, Hori M, Nakagawa Y, Hayashi T, Sakamoto S, Ohnishi J, Takeuchi S, Mihara Y,
Shiga T, Murakami K, Urayama O. Tickling stimulation causes the up-regulation of the kallikreinfamily in the submandibular gland of the rat. Behav Brain Res doi: 10.1016/j.bbr.2012.09.001.,
2012

15

分子腫瘍学	 a）英文論文
1. Oishi H, Itoh S, Matsumoto K, Ishitobi H, Suzuki R, Ema M, Kojima T, Uchida K, Kato M, Miyata
T, Takahashi S. Delayed cutaneous wound healing in Fam129b/Minerva-deficient mice. J Biochem
152(6):549-555, 2012
2. Shimazui T, Yoshikawa K, Miyazaki J, Kojima T, Inai H, Ando S, Uemura H, Uchida K,
Nishiyama H. Systemic transduction of p16INK4A antitumor peptide inhibits the growth of MBT-2
mouse bladder tumor cell line grafts. Int J Oncol doi: 10.3892/ijo.2012.1752., 2012 .
3. Takase H, Matsumoto K, Yamadera R, Kubota Y, Otsu A, Suzuki R, Ishitobi H, Mochizuki H,
Kojima T, Takano S, Uchida K, Takahashi S, Ema M. Genome-wide identification of endothelial
cell-enriched genes in the mouse embryo. Blood 120(4):914-923, 2012

生理化学	 a）英文論文1. Chen Q, Hongu T, Sato T, Zhang Y, Ali W, Cavallo JA, van der Velden A, Tian H, Di Paolo G,
Nieswandt B, Kanaho Y, Frohman MA. Key roles for the lipid signaling enzyme phospholipase d1
in the tumor microenvironment during tumor angiogenesis and metastasis. Sci Signal 5(249):ra79,
2012
2. Hasegawa H, Noguchi J, Yamashita M, Okada R, Sugimoto R, Furuya M, Unoki T, Funakoshi Y,
Baba T, Kanaho Y. Phosphatidylinositol 4-phosphate 5-kinase is indispensable for mouse
spermatogenesis. Biol Reprod 86(5):136 (1-12), 2012
3. Kanaho Y, Sato T, Hongu T, Funakoshi Y. Molecular mechanisms of fMLP-induced superoxide
generation

anddegranulation

in

mouse

neutrophils.

Adv

Biol

Regul

doi:

10.1016/j.jbior.2012.09.001., 2012
4. Kanaho Y, Unoki T. Regulation and functions of the lipid kinase PIP5K γ661 at synapses. Adv Biol
Regul 52(1):59-65, 2012
5. Makyio H, Ohgi M, Takei T, Takahashi S, Takatsu H, Katoh Y, Hanai A, Ueda T, Kanaho Y, Xie Y,
Shin HW, Kamikubo H, Kataoka M, Kawasaki M, Kato R, Wakatsuki S, Nakayama K. Structural
basis for Arf6-MKLP1 complex formation on the Flemming body responsible for cytokinesis.
EMBO J 31(11):2590-2603, 2012
6. Neely GG, Rao S, Costigan M, Mair N, Racz I, Milinkeviciute G, Meixner A, Nayanala S, Griffin
RS, Belfer I, Dai F, Smith S, Diatchenko L, Marengo S, Haubner BJ, Novatchkova M, Gibson D,
Maixner W, Pospisilik JA, Hirsch E, Whishaw IQ, Zimmer A, Gupta V, Sasaki J, Kanaho Y,
Sasaki T, Kress M, Woolf CJ, Penninger JM. Construction of a global pain systems network
highlights phospholipid signaling as a regulator of heat nociception. PLoS Genet 8(12):e1003071,
2012
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7. Unoki T, Matsuda S, Kakegawa W, Van NT, Kohda K, Suzuki A, Funakoshi Y, Hasegawa H,
Yuzaki M, Kanaho Y. NMDA receptor-mediated PIP5K activation to produce PI(4,5)P(2) isessential for AMPA receptor endocytosis during LTD. Neuron 73(1):135-148, 2012	 	
 分子薬理学	
 a）英文論文1. Chtanova T, Hampton HR, Waterhouse LA, Wood K, Tomura M, Miwa Y, Mackay CR, Brink R,
Phan TG. Real-time interactive two-photon photoconversion of recirculating lymphocytes fordiscontinuous cell tracking in live adult mice. J Biophotonics doi: 10.1002/jbio.201200175, 2012
2. Kita M, Yoneda K, Hirayama Y, Yamagishi K, Saito Y, Sugiyama Y, Miwa Y, Ohno O, Morita M,
Suenaga K, Kigoshi H. Fluorescent aplyronine a: intracellular accumulation and disassembly of actin
cytoskeleton in tumor cells. Chembiochem 13(12):1754-1758, 2012
3. Kudo K, Momotake A, Tanaka JK, Miwa Y, Arai T. Environmental polarity estimation in living
cells by use of quinoxaline-based full-colored solvatochromic fluorophore PQX and its derivatives.
Photochem Photobiol Sci 11(4):674-678, 2012
4. Matsumoto K, Azami T, Otsu A, Takase H, Ishitobi H, Tanaka J, Miwa Y, Takahashi S, Ema M.
Study of normal and pathological blood vessel morphogenesis in Flt1-tdsRed BAC Tg mice.
Genesis 50(7):561-571, 2012
5. Shibata ACE, Fujiwara TK, Chen L, Suzuki KGN, Ishikawa Y, Nemoto YL, Miwa Y, Kalay Z,
Chadda R, Naruse K, Kusumi A. Archipelago architecture of the focal adhesion: membrane
molecules freely enter and exit from the focal adhesion zone. Cytoskeleton 69(6):380-392, 2012
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分子神経生物学	 a）英文論文1. Nagamine S, Tamba M, Ishimine H, Araki K, Shiomi K, Okada T, Ohto T, Kunita S, Takahashi S,
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3. Wang R, Iwakura Y, Araki K, Keino-Masu K, Masu M, Wang XY, Takei N, Higashiyama S, Nawa
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微生物学	
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1. 金谷穣, 鍋倉宰, 渋谷和子, 渋谷彰. Immune Regulation in Hematological Malignancies 急性GVHD発症における活性化免疫受容体DNAM-1の重要な役割. 臨床血液 53(5):497-503, 2012
2. 渋谷彰, 金丸和正. 【ウイルス感染と免疫・アレルギー】 アレルギーと抑制性免疫グロブリン様受
容体. アレルギーの臨床 32(12):1111-1116, 2012
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新しい受容体、Allergin-1. 臨床免疫・アレルギー科 58(2):197-203, 201219

遺伝医学	
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2. Horiuchi Y, Iida S, Koga M, Ishiguro H, Iijima Y, Inada T, Watanabe Y, Someya T, Ujike H, Iwata
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serum total cholesterol levels is a risk factor of ischemic stroke for general Japanese population: theJPHC study. Atherosclerosis 221(2):565-569, 2012	 20

2. Emerging Risk Factors Collaboration (Yamagishi K, collaborator). Adult height and the risk ofcause-specific death and vascular morbidity in 1 million people: individual participant
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Rossing P, Sairenchi T, Tonelli M, Vassalotti JA, Yamagishi K, Coresh J, de Jong PE, Wen CP,
Nelson RG; Chronic Kidney Disease Prognosis Consortium. Associations of kidney diseasemeasures with mortality and end-stage renal disease in individuals with and without diabetes: ameta-analysis. Lancet 380(9854):1662-1673, 2012
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12. Hitomi Y, Adachi T, Tsuchiya N, Honda Z, Tokunaga K, Tsubata T. Human CD72 splicing
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22. Nagao M, Iso H, Yamagishi K, Date C, Tamakoshi A; JACC Study Group. Meat consumption in
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統計数理 60:317-325, 2012
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再生幹細胞生物学	
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医工学	 a)英文論文	 1. Yanagi K, Fukuda E, Jotatsu Y, Shikano M, Miyake S. Regulatory frameworks for cell therapy
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1. 柳健一. 新たに承認された血糖降下薬における承認審査期間と製造販売後調査計画の動向.
レギュラトリーサイエンス学会誌 2:93-99, 2012

実験動物学	
 a）英文論文1. Harada N, Ito K, Hosoya T, Mimura J, Maruyama A, Noguchi N, Yagami K, Morito N, Takahashi
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10.1210/en.2012-1789., 2012

医学物理学	
 a）英文論文1. Hashii H, Hashimoto T, Okawa A, Shida K, Isobe T, Hanmura M, Nishimura T, Aonuma K, Sakae
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1. 磯辺智範, 森祐太郎, 榮武二, 松原孝祐, 五十嵐隆元. 放射線防護に関する説明のために必要な知識. 日本放射線技術学会雑誌 68(10):1419-1427, 2012
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Principles and Applications (First edition)" (edited by Sauerwein WAG, Moss R, Wittig A,
Nagakawa Y), Springer (Germany) 2012; pp287-328d）英文以外の著書
1. 磯辺智範. Part1 MR 第1章. MRの成り立ち, 第3章. MR現像から画像化まで, 第10章. アーチフ
ァクト, 第12章. そのほか知っておきたい知識-MRS, Part2 超音波 第1章. 超音波の基礎, Part3
眼底写真撮影 第1章. 眼底写真撮影の基礎; "MR・超音波・眼底 基礎知識図解ノート (第１版)”(編集 磯辺智範), 金原出版 (東京) 2012; pp2-9, 32-47, 152-175, 207-211, 252-257,362-364
2. 磯辺智範. 第1章. 放射線と放射能の基礎知識; "放射線医療技術（31） 図解放射線防護ミニマ
ム基礎知識 (第1版)” (編集 日本放射線技術学会), 望月印刷 (埼玉) 2012; pp1-22
3. 磯辺智範. 1. 基礎医学大要; "3rd edition診療放射線技師 ブルーノート 基礎編 (第3版)” (編集福士政広), メジカルビュー社 (東京) 2012; pp1-254
4. 磯辺智範, 榮武二, 櫻井英幸. 第4章. 陽子線, 第5章. 陽子線; "放射線外科治療の進歩 (第1版)” (編集 井上洋), メディカ出版 (大阪) 2012; pp44-50, 81-87
5. 高田健太. 第1章. 超音波の基礎; "MR・超音波・眼底 基礎知識図解ノート(第1版) (第1版)” (編集 磯辺智範), 金原出版 (東京) 2012; pp252-257, 362-364
6. 高田健太, 佐藤英介. 1. 基礎医学大要; "診療放射線技師 グリーンノート 基礎編 (第2版)” (編集 福士政広), メジカルビュー社 (東京) 2012; pp2-68

26

放射線生物学	 a）英文論文1. Fukumitsu N, Ishida M, Terunuma T, Mizumoto M, Hashimoto T, Moritake T, Okumura T, Sakae
T, Tsuboi K, Sakurai H. Reproducibility of image quality for moving objects using
respiratory-gated computed tomography: a study using a phantom model. J Radiat Res
53(6):945-953, 2012
2. Fukumitsu N, Oshiro Y, Hashimoto T, Okumura T, Mizumoto M, Moritake T, Tsuboi K, Sakae T,
Sakurai H. Verification of beam delivery using fibrosis after proton beam irradiation to the lungtumor. Lung Cancer 77(1):83-88, 2012
3. Hashimoto T, Isobe T, Hashii H, Kumada H, Tada H, Okumura T, Tsuboi K, Sakae T, Aonuma K,
Sakurai H. Influence of secondary neutrons induced by proton radiotherapy for cancer patients withimplantable cardioverter defibrillators. Radiat Oncol 7:10, 2012
4. Kanemoto A, Ishikawa H, Mizumoto M, Okumura T, Hashimoto T, Oshiro Y, Fukumitsu N, Tsuboi
K, Sakae T, Sakurai H. Proton beam therapy for liver metastasis from breast cancer:Five casereports and a review of the literatures. International Cancer Conference Journal 1:210-214, 2012
5. Mizumoto M, Okumura T, Hashimoto T, Fukuda K, Oshiro Y, Fukumitsu N, Abei M, Kawaguchi A,
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H. Evaluation of liver function after proton beam therapy for hepatocellular carcinoma. Int J
Radiat Oncol Biol Phys 82(3):e529-535, 2012
6. Moritake T, Fujita H, Yanagisawa M, Nakawatari M, Imadome K, Nakamura E, Iwakawa M, Imai
T. Strain-dependent damage in mouse lung after carbon ion irradiation. Int J Radiat Oncol Biol
Phys 84(1):e95-e102, 2012
7. Oshiro Y, Mizumoto M, Okumura T, Hashimoto T, Fukumitsu N, Ohkawa A, Kanemoto A, Hashii
H, Ohno T, Sakae T, Tsuboi K, Sakurai H. Results of proton beam therapy without concurrent
chemotherapy for patients with unresectable stage III non-small cell lung cancer. J Thorac Oncol
7(2):370-375, 2012
8. Takano S, Kato Y, Yamamoto T, Kaneko MK, Ishikawa E, Tsujimoto Y, Matsuda M, Nakai K,
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p53, and internexin as prognostic factors of glial tumors. J Neurooncol 108(3):361-373, 2012
9. Tsuboi K. DNA-PK targeting virotherapy, a promising approach. Transl Cancer Res 1(1):2-3, 2012c）英文著書1. Ishikawa E, Takano S, Ohno T, Tsuboi K. Chapter 9. Adoptive cell transfer therapy for malignant
glioma; in "Advances in Experimental Medicine and Biology, Glioma" (edited by Yamanaka R),
Landes Bioscience (Austin) and Springer Science + Business Media, LLC (New York) 2012;
pp109-120

27

生物物理化学	 a)英文論文1. Hall D. Semi-automated methods for simulation and measurement of amyloid fiber distributions
obtained from transmission electron microscopy experiments. Anal Biochem 421(1):262-277, 2012
2. Hall D, Edskes H. Computational modeling of the relationship between amyloid and disease.
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3. Hall D, Huang L. On the use of size exclusion chromatography for the resolution of mixed amyloid
aggregate distributions: I. equilibrium partition models. Anal Biochem 426(1):69-85, 2012

生命反応化学	 a)英文論文1. Aiba Y, Honda Y, Han Y, Komiyama M. Introduction of multiphosphonate ligand to peptide
nucleic acid for metal ion conjugation. Artif DNA PNA XNA 3(2):73-79, 2012
2. Aiba Y, Komiyama M. Artificial site-selective DNA cutters to manipulate single-stranded DNA.
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3. Gao Z, Zhi C, Bando Y, Golberg D, Komiyama M, Serizawa T. Efficient disentanglement of boron
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2:6200-6208, 2012
4. Ishizuka T, Komiyama M, Xu Y. G-rich sequence-specific recognition and scission of humangenome by PNA/DNA hybrid G-quadruplex formation. Angew Chem Int Ed Engl
51(29):7198-7202, 2012
5. Ishizuka T, Xu Y, Komiyama M. A chemistry-based method to detect individual telomere length ata single chromosome terminus. J Am Chem Soc doi: 10.1021/ja308481c., 2012
6. Katada H, Harumoto T, Shigi N, Komiyama M. Chemical and biological approaches to improve theefficiency of homologous recombination in human cells mediated by artificial restriction DNA
cutter. Nucleic Acids Res 40(11):e81, 2012
7. Komiyama M, Sumaoka J. Design and applications of artificial restriction DNA cutters forsite-selective scission of genomes. Bull. Chem. Soc. Jpn. 85:533-544, 2012
8. Kuzuya A, Tanaka K, Katada H, Komiyama M. Enzyme treatment-free and ligation-independent
cloning using caged primers in polymerase chain reactions. Molecules 17(1):328-340, 2012
9. Murakami T, Sumaoka J, Komiyama M. Sensitive RNA detection by combining 3-way junction
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10. Noguchi E, Shigi N, Komiyama M. Intracellular localization of PNA in human cells upon its
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11. Yamazaki T, Aiba Y, Yasuda K, Sakai Y, Yamanaka Y, Kuzuya A, Ohya Y, Komiyama M.
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環境生物学	
 a）英文論文1. Hirose R, Miura T, Sha R, Shinkai Y, Tanaka-Kagawa T, Kumagai Y. A method for detecting
covalent modification of sensor proteins associated with 1,4-naphthoquinone-induced activation ofelectrophilic signal transduction pathways. J Toxicol Sci 37(5):891-898, 2012
2. Kanda H, Toyama T, Shinohara-Kanda A, Iwamatsu A, Shinkai Y, Kaji T, Kikushima M, Kumagai
Y. S-Mercuration of rat sorbitol dehydrogenase by methylmercury causes its aggregation and therelease of the zinc ion from the active site. Arch Toxicol 86(11):1693-1702, 2012
3. Kumagai Y, Shinkai Y, Miura T, Cho AK. The chemical biology of naphthoquinones and its
environmental implications. Annu Rev Pharmacol Toxicol 52:221-247, 2012
4. Nishida M, Sawa T, Kitajima N, Ono K, Inoue H, Ihara H, Motohashi H, Yamamoto M, Suematsu
M, Kurose H, van der Vliet A, Freeman BA, Shibata T, Uchida K, Kumagai Y, Akaike T.
Hydrogen sulfide anion regulates redox signaling via electrophile sulfhydration. Nat Chem Biol
8(8):714-724, 2012
5. Shinkai Y, Iwamoto N, Miura T, Ishii T, Cho AK, Kumagai Y. Redox cycling of
1,2-naphthoquinone by thioredoxin1 through Cys32 and Cys35 causes inhibition of its catalytic
activity and activation of ASK1/p38 signaling. Chem Res Toxicol 25(6):1222-1230, 2012
6. Shinkai Y, Kaji T. Cellular defense mechanisms against lead toxicity in the vascular system. Biol
Pharm Bull 35(11):1885-1891, 2012
7. Yamada H, Akahoshi N, Kamata S, Hagiya Y, Hishiki T, Nagahata Y, Matsuura T, Takano N, Mori
M, Ishizaki Y, Izumi T, Kumagai Y, Kasahara T, Suematsu M, Ishii I. Methionine excess in diet
induces acute lethal hepatitis in mice lacking cystathionine γ-lyase, an animal model ofcystathioninuria. Free Radic Biol Med 52(9):1716-1726, 2012d)英文以外の著書
1. 熊谷嘉人. 環境中親電子リガンドの細胞内侵入とそれに伴うシグナル伝達の模倣および攪乱;実験医学「活性酸素・ガス状分子による恒常性制御と疾患」 30, 羊土社（東京）2012; pp70-75
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 a)英文論文1. Ishii T, Warabi E, Yanagawa T. Novel roles of peroxiredoxins in inflammation, cancer and innate
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in

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環境微生物学	 a)英文論文1. Kato SI, Nagata K, Takeuchi K. Cell tropism and pathogenesis of measles virus in monkeys. Front
Microbiol 3:14, 2012
2. Takeuchi K, Nagata N, Kato SI, Ami Y, Suzaki Y, Suzuki T, Sato Y, Tsunetsugu-Yokota Y, MoriK, Van Nguyen N, Kimura H, Nagata K. Wild-type measles virus with the hemagglutinin proteinof the edmonston vaccine strain retains wild-type tropism in macaques. J Virol 86(6):3027-3037,
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分子発生生物学	 a)英文論文1. Mukaigasa K, Nguyen LTP, Li L, Nakajima H, Yamamoto M, Kobayashi M. Genetic evidence ofan evolutionarily conserved role for Nrf2 in the protection against oxidative stress. Mol Cell Biol
32(21):4455-4461, 2012b）英文以外の論文
1. 田中佐代子, 小林麻己人, 三輪佳宏. 科学者によるサイエンスイラストレーション作成の実態.
芸術研究報 32:59-70, 201230

環境保健学（産業精神医学・宇宙医学）	
 a）英文論文	 1. Sasahara S, Tomotsune Y, Ohi Y, Suzuki S, Seki A, Sakano J, Yamazaki Y, Matsuzaki I. Life
experiences are important factors of making stronger SOC (Sense of Coherence) on the workers in
Tsukuba Research Park City (TRPC). World Acad Sci Eng Technol 68:103-107, 2012b） 英文以外の論文
1. 小林直紀, 笹原信一朗, 友常祐介, 道喜将太郎, 商真哲, 大井雄一, 羽岡健史, 梅田忠敬,
吉野聡, 松崎一葉. メンタルヘルス不全に伴う病気休業と休復職に関する規則・制度との関連に関する研究. 産業衛生学雑誌 54(6):286-293, 2012
2. 笹原信一朗, 友常祐介, 小林直紀, 道喜将太郎, 商真哲, 大井雄一, 羽岡健史, 梅田忠敬,
吉野聡, 松崎一葉. うつ病の増加に伴う病気休暇ならびに病気休職期間と金銭補償期間との関連に関する予備的研究 〜労使双方により良い休職制度を目指して〜. 体力栄養免疫学雑誌
22:74-81, 2012
3. 羽岡健史, 鈴木瞬, 小林直紀, 宇佐見和哉, 友常祐介, 吉野聡. リワークプログラム利用中のス
トレス関連要因の変化. 臨床精神医学 41(12):1749-1755, 2012

長寿医学寄附講座	
 a）英文論文1. Sasahara S, Tomotsune Y, Ohi Y, Suzuki S, Seki A, Sakano J, Yamazaki Y, Matsuzaki I. Life
experiences are important factors of making stronger SOC(Sense of Coherence) on the workers in
Tsukuba Research Park City(TRPC). World Acad Sci Eng Technol 68:103-107, 2012b）英文以外の論文
1. 笹原信一朗, 友常祐介, 小林直紀, 道喜将太郎, 商真哲, 大井雄一, 羽岡健史, 梅田忠敬,
吉野聡, 松崎一葉. うつ病の増加に伴う病気休暇ならびに 病気休職期間と金銭補償期間との関連に関する予備的研究〜労使双方により良い休職制度を目指して〜. 体力・栄養・免疫学雑誌 22:74-81, 2012d）英文以外の著書
1. 笹原信一朗. 心の折れない部下の育て方. メディアファクトリー新書 2012年 (全189ページ)
2. 望月昭英. 意識障害; "病気と薬パーフェクトBOOK2012「薬局」2012増刊号” (編集 横田千津子,
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池田宇一, 監修・編集 大越教夫), 南山堂 (東京) 2012; pp202-20331循環生理学a）英文論文1. Nakamagoe K, Mamada N, Shiigai M, Shimizu K, Koganezawa T, Tamaoka A. Recurrent isolated
abducens nerve paresis associated with persistent trigeminal artery variant. Intern Med
51(16):2213-2216, 2012
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medullary lesion. J Clin Neurosci 19(11):1597-1599, 2012
3. Sabino-Silva R, Ceroni A, Koganezawa T, Michelini LC, Machado UF, Antunes VR.
Baroreceptor-mediated activation of sympathetic nerve activity to salivary glands. Physiol Behav
107(3):390-396, 2012

医学英語教育	 a）英文論文
1. Purdue Brian K. Instant Academic Writing Organization and Format in a Digital Language Lab:First, Copy and Paste. Studies in Foreign Language Education (外国語教育論集 ). 34:79-94,
201232