The next generationof animal eye researchstarts now.

RETINAL IMAGING

Exceptional retinal
microscopy
Phoenix Research Labs’ technologies are designed by scientists, for scientists,
to support eye and eye-brain research using laboratory animals. They are notad hoc adaptations of clinical instruments. Our optimization for the rodent eyeleads to extraordinary performance and high quality images that enables a newera of in vivo observations. Phoenix has played a part in numerous longitudinalstudies previously not possible.

MICRON IV:•M ouse retina resolution below 3 microns•F luorescein angiography withresolution to observe RBC• Image arbitrary fluorophores•R eal-time display with capture of stills
or videos•N ew software, ‘Discover’, gives you thetools to capture the remarkable images

A single device with multiple modalities

Bright field: Wide field of view images of mice and rat retinas with high clarity

Angiography: Resolves the capillary bed and observes the flow of red blood cells

Fluorescent Imaging: Observe arbitrary fluorescent molecules across the visible spectrum:‘Discover’ the advances we’ve madeOur new image processing software,Discover, extends the reach of yourresearch with features designed to help
you capture the best images possible:• Image Processing Routines• Contrast Stretch• Increased Usability• Line profiles

MEASURE VESSEL CALIBER
Discover provides detailed line profiles
to accurately measure vessels.

TRUE IMAGE-GUIDED OCT

Next-generation OCTfor small animals
Phoenix Research Labs’ OCT2 represents a tremendous leap forward in true
image-guided OCT imaging. We’ve updated and improved every aspect ofour already exceptional system; from improved optics in our new scan head,to dramatic performance improvements in our image processing hardware& software. We’ve designed to make capturing stunning OCT images easierand faster than ever before.
All new OCT scan head• New OCT scan head design ismore robust, easier to install andstable for clear imaging• Improved software allows precise alignment of scan to image

Updated state-of-the-art performance• Upgraded OCT engine• Enhanced depth allows studies of sclera• Classical OCT artifacts eliminated• Obtain True-Image Guided OCTimages in under 2 minutes

OCT scan location is presented simultaneously on a real-time Micron IV+ bright-field
image. Changing the OCT scan location is as easy as moving the scan line across yourimage. Combining an OCT scan with fluorescein is possible with the simple turnof a filter on the Micron IV+, and can be captured during the same sedation session.

NEW: Phoenix 3D display gives a new way of visualizing structures
Our revolutionary new 3D display integrates
our stunning bright field images with ournew 3D OCT presentation to give you deep
insights into the retinal structure. Scroll
through the 3D layer to reveal vascular andlayer details never seen before.

INTERACTIVE OCT ANALYSISIntelligent eyesegmentation
Using OCT data recorded from your Phoenix Micron IV+ camera,
InSight can be employed to segment the retinal layers automatically orinteractively.

Automatic when you want it, control when you need it.
InSight automatically calculates layer segments for the retina or, when the pathology
is abnormal, our interactive controls let you easily adjust the segmentation in any way
you choose.

Outstanding 3Dvisualization

InSight 3D* gives you the ability to select a scan area directly on yourbright field image and extract a 3D OCT segmentation that you can rotate,view and scan. Our new segmentation engine will visualize layers like you
have never seen before.
InSight 3D
segmentation
InSight 3D segmentation will provide global
insights into layers andother retinal anomalies.
Release is scheduled forsummer 2015 and will
include heat maps andother 3D analysis tools.

InSight 3D available: Summer 2015*

A complete imaging systemfor eye research
A powerful set of modalities brought to yourresearch program and in a physically compact
format. This bench-top system can be acquired
as a retinal imager alone, or with our powerfulcompact OCT2. Taken together or alone, nofloor space is needed, releasing limited lab floor
space to better serve your needs.

Specifications:
MicronIV+ Retinal Microscope
Transverse resolution

3 microns (mice)Pixel size on retina

2 microns (mice)

Imaging modes

Bright field
Fluorescein and Evan’s blue angiography
Four position filter wheel for selection of arbitrary fluorophores for fluorescent studies

Dynamic imaging rate

20 frames per second to 0.5 frames per second

Imaging dynamic range

60 dB

Image sensor

Custom built 3CCD with extended sensitivity in the NIR

Field of view

50 degrees

Data export

All common image and video formats

Optical Coherence Tomography
Longitudinal resolution

1.8 microns

in tissue
Imaging depth

1.4 mmScan rate

20,000 line per sec

Frame averaging withUp to 50 frames

correlate and add
Transverse scan length in mice

250 to 1,200 microns (mice)

Export formats

All common image formats

6630 Owens Drive, Pleasanton, California 94588
925.485.1100 T 925.485.1155 F www.phoenixreslabs.com