Kentaro Misaki
E-mail: kmisaki@u-shizuoka-ken.ac.jp52-1 Yada, Suruga-ku, Shizuoka 422-8526, Japan
Phone/FAX: +81-77-527-6329

Education
Ph.D. in Department of Environmental Engineering, Graduate School of Engineering,
Kyoto Univ., Kyoto, Japan, 2007
M.Sc. in Department of Human and Environmental Studies, Graduate School of Humanand Environmental Studies, Kyoto Univ., Kyoto, Japan, 2001
B.Sc. in Chemistry System, Faculty of Science, Kyoto Univ., Kyoto, Japan, 1999

Employment
University of Shizuoka, School of Nursing, Research Associate, 2015-present
Kyoto Univ., Research Center for Environmental Quality Management (RCEQM),
Graduate School of Engineering, Postdoctoral Research Fellow (InstituteResearcher), 2012-2015
Ehime Univ., Center for Marine Environmental Studies (CMES), Global Center for
Excellence (G-COE) Researcher, 2010-2012
Juntendo Univ., Institute for Environmental and Gender-specific Medicine, Graduate
School of Medicine, Postdoctoral Research Fellow, 2007-2010

Professional activities
The Japanese Environmental Mutagen Society (JEMS)Japan Society for Atmospheric Environment (JSAE)
Japan Society of Allergology (JSA)
Japan Society for Environmental Chemistry (JEC)
Japan Society on Water Environment (JWE)
Japan Society of Endocrine Disrupters Research (JSEDR)The Chemical Society of Japan (CSJ)
American Chemical Society (ACS)Japan Endotoxin and Innate Immunity Society (JEIIS)

Publications
1. K. Misaki, N. M. Tue, T. Takamura-Enya, H. Takigami, G. Suzuki, L. H. Tuyen, S.
Takahashi and S. Tanabe. Antiandrogenic and estrogenic activity evaluation ofoxygenated and nitrated polycyclic aromatic hydrocarbons using chemicallyactivated luciferase expression assays. Int. J. Environ. Res. Public Health, 20(1), 80,2023.
2. K. Misaki, H. Takano, H. Kanazawa and K. Inoue. Biological response-enhancingactivity with antigens in A549 cells exposed to representative polycyclic aromatichydrocarbons. ACS Omega, 6(34), 22224-22232, 2021.
3. M. Yasui, T. Fukuda, A. Ukai, J. Maniwa, T. Imamura, T. Hashizume, H. Yamamoto, K.
Shibuya, K. Narumi, Y. Fujiishi, E. Okada, S. Fujishima, M. Yamamoto, N. Otani, M.
Nakamura, R. Nishimura, M. Ueda, M. Mishima, K. Matsuzaki, A. Takeiri, K. Tanaka, Y.
Okada, M. Nakagawa, S. Hamada, A. Kajikawa, H. Honda, J. Adachi, K. Misaki, K.
Ogawa and M. Honma. Weight of evidence approach using a TK gene mutation assay
with human TK6 cells for follow-up of positive results in Ames tests: A collaborative
study by MMS/JEMS. Genes and Environ., 43(1):7, 2021.
4. K. Misaki, S. Matsuda, T. Matsuda, T. Kusakabe and Y. Shimizu. Detection of DNA
damage formation by natural organic matter using EGFP-fused MDC1-expressing cells.
Chemosphere 235, 169-174, 2019.
5. K. Misaki, Y. Morita, K. Kobayashi, Y. Sugawara, Y. Shimizu and T. Kusakabe.
Evaluation of algal photosynthesis inhibition activity for dissolved organic matterwith the consideration of inorganic and coloring constituents. Chemosphere 224,333-342, 2019.
6. K. Misaki, H. Takano, H. Kanazawa and K. Inoue. Adverse effects of DEP andnanomaterials on bacteria-induced pulmonary disorder. Endotoxin and Innate
Immunity (Japanese), 19, 46-50, 2016.
7. K. Misaki, T. Takamura-Enya, H. Ogawa, K. Takamori and M. Yanagida.
Tumour-promoting activity of polycyclic aromatic hydrocarbons and their oxygenatedor nitrated derivatives. Mutagenesis 31(2), 205-213, 2016.
8. K. Misaki, G. Suzuki, N. M. Tue, S. Takahashi, M. Someya, H. Takigami, Y. Tajima, T. K.
Yamada, M. Amano, T. Isobe and S. Tanabe. Toxic identification and evaluation ofandrogen receptor antagonistic activities in acid-treated liver extracts ofhigh-trophic level wild animals from Japan. Environ. Sci. Technol. 49(19),11840-11848, 2015.
9. L. H. Tuyen, N. M. Tue, G. Suzuki, K. Misaki, P. Hung Viet, S. Takahashi and S. Tanabe.
Aryl hydrocarbon receptor mediated activities in road dust from a metropolitan area,Hanoi-Vietnam: Contribution of polycyclic aromatic hydrocarbons (PAHs) and humanrisk assessment. Sci. Total Environ. 491-492, 246-254, 2014.
10. J. –W. Kim, N. M. Tue, T. Isobe, K. Misaki, S. Takahashi, P. H. Viet and S. Tanabe.
Contamination by perfluorinated compounds in water recycling and disposal sites inVietnam. Environ. Monit. Assess. 185(4), 2909-2919, 2013.
11. M. Okada, Y. Hozumi, K. Iwazaki, K. Misaki, M. Yanagida, Y. Araki, T. Watanabe, H.
Yagisawa, M. K. Topham, K. Kaibuchi and K. Goto. DGKζ is involved in LPS-activatedphagocytosis through IQGAP1/Rac1 pathway. Biochem. Biophys. Res. Commun.
420(2), 479-84, 2012.
12. K. Misaki, Y. Hisamatsu, H. Suzuki and T. Takamura-Enya. Evaluation of themutagenicity of nitration products derived from phenalenone (1H-phenalene-1-one).
Mutagenesis 23(5), 359-366, 2008.
13. K. Misaki, M. Suzuki, M. Nakamura, H. Handa, M. Iida, T. Kato, S. Matsui and T.

Matsuda. Aryl hydrocarbon receptor and estrogen receptor ligand activity of organic
extracts from road dust and diesel exhaust particulates. Arch. Environ. Contam.
Toxicol. 55(2), 199-209, 2008.
14. T. Matsuda, A. Matsumoto, M. Uchida, R. Kanaly, K. Misaki, S. Shibutani, T. Kawamoto,
K. Kitagawa, K. I. Nakayama, K. Tomokuni and M. Ichiba. Increased formation ofhepatic N2-ethylidene-2’-deoxyguanosine DNA adduct in aldehyde dehydrogenase 2knockout mice treated with ethanol. Carcinogenesis 28(11), 2363-2366, 2007.
15. K. Misaki, H. Kawami, T. Tanaka, H. Handa, M. Nakamura, S. Matsui and T. Matsuda.
Aryl hydrocarbon receptor ligand activity of polycyclic aromatic ketones andpolycyclic aromatic quinones. Environ. Toxicol. Chem. 26(7), 1370-1379, 2007.
16. K. Misaki, S. Matsui and T. Matsuda. Metabolic enzyme induction by HepG2 cells
exposed to oxygenated and nonoxygenated polycyclic aromatic hydrocarbons. Chem.
Res. Toxicol. 20(2), 277-283, 2007.
17. P. –H. Chou, S. Matsui, K. Misaki and T. Matsuda. Isolation and identification ofxenobiotic aryl hydrocarbon receptor ligands in dyeing wastewater. Environ. Sci.
Technol. 41(2), 652-657, 2007.
18. R. Tamura, D. Fujimoto, Z. Lepp, K. Misaki, H. Miura, H. Takahashi, T. Ushio, T. Nakai
and K. Hirotsu. Mechanism of preferential enrichment, an unusual enantiomeric
resolution phenomenon caused by polymorphyic transition during crystallization ofmixed crystals of two enantiomers. J. Am. Chem. Soc. 124(44), 13139-13153, 2002.

Conference presentations in English
1. K. Misaki, H. Takano, H. Kanazawa and K. Inoue, The search for polycyclic aromaticquinones with amplifying action in antigen response. The Japanese Society ofAllergology / the World Allergy Organization the 27th World Allergy Congress.
online, Japan, September 2020.
2. K. Misaki, H. Takano, H. Kanazawa and K. Inoue, Adverse Effects of DEP andNanomaterials on Bacteria-Induced Pulmonary Disorder. The 8th Congress of theInternational Federation of Shock Societies. Tokyo, Japan, October 2016.
3. K. Misaki, Y. Morita, T. Kusakabe and Y. Shimizu, Evaluation of Algal Photosynthesis
Inhibition Activity for Natural Organic Matter, The 4th Symposium on Research andEducation Center for the Risk Based Asian Oriented Integrated Watershed
Management. Johor Bahru, Malaysia, December 2014.
4. K. Misaki, G. Suzuki, N. M. Tue, M. Someya, H. Takigami, Y. Tajima, T. K. Yamada, M.
Amano, T. Isobe, S. Takahashi and S. Tanabe, Contribution of organochlorine
pesticides and PCBs as androgen receptor antagonists in acid-treated liver extractsof higher trophic wild animals, 32nd International Symposium on Halogenated
Persistent Organic Pollutants- Dioxin 2012, Cairns, Australia, August 2012.
5. K. Misaki, T. Takamura, K. Takamori and M. Yanagida, Tumor promoting activity ofpolycyclic aromatic compounds and the investigation about the mode of action, TheSociety of Environmental Toxicology and Chemistry (SETAC) Asia/Pacific Joint
Conference, 1st International Conference on Environmental Pollution,
Restoration, and Management, Ho Chi Minh, Vietnam, March 2010.
6. K. Misaki, H. Kawami, T. Matsuda and S. Matsui, Aryl hydrocarbon receptor (AhR)

ligand activity of polycyclic aromatic quinones and ketones, 4th International Water
Association, Assessment and Control of Hazardous Substances in Water-ECOHAZARD 2003-, Aachen, Germany, September 2003.
7. R. Tamura, D. Fujimoto, K. Misaki, Z. Lepp, H. Takahashi and T. Ushio, Mechanism ofPolymorphic Transition Responsible for Preferential Enrichment, 15th International
Conference on the Chemistry of the Organic Solid State, Mainz, Germany, August2001.