Messages from Overseas Research Institutions (1)The message from Dr. Ronald N. Germain

ロナルド ･ジャーメイン博士･ジャーメイン博士からのメッセージ
博士からのメッセージ （和訳）
和訳）

To Professor Akira, members of the IFReC, and colleagues at Osaka University

審良教授、IFReC ならびに大阪大学の研究者の皆様へ

Congratulations on the occasion of the completion of the beautiful new Integrated
Life Sciences Building that will house many of the investigators of the IFReC andprovide an extraordinary environment for the cutting edge - may I say 'visionary' research in imaging of the immune system that will be conducted as part of thisprogram.

この度は “融合型生命科学総合研究棟” のご竣工、おめでとうございます。この施設は、IFReCの多くの研究者のために素晴らしい研究環境を提供することでしょう。それはIFReCのプログラム趣旨である - “先見性のある”というべきでしょうか- 最先端の‘免疫イメージング’研究にふさわしいものです。

I have been privileged to be named a foreign associate of the IFReC and have alreadybenefited greatly in my own research by interactions with IFReC colleagues at theseveral symposia that have taken place in Osaka, as well as by the support provided
for research fellows in my laboratory.

私はIFReCの海外連携機関の研究者の一人として、大阪で行われたいくつかのシンポジウムでのIFReCの研究者との交流を通じて、私自身の研究に恩恵を受けていること、またIFReCから私たちの研究室にサポートを頂いていることを光栄に感じています。

I am also very pleased that my former associate Dr. Masaru Ishii is part of the IFReC
and will share in the benefits of this new research facility.

また、 私のかつての共同研究者である石井優博士がIFReCのメンバーとなり、この新しい環境で研究を行うことを喜ばしく思っています。

I look forward to visiting the new building myself in the near future and spending
many hours in exciting and productive discussions about the immune system withmy colleagues.

私自身も近い将来、新研究棟を訪問し、免疫システムに関してIFReCの研究者たちと刺激的で生産的な議論を活発に行いたいと考えています。

The international aspect of the IFReC is one of its strongest attributes and I am
grateful as a foreign member to have this opportunity to recognize and praise thisimportant milestone in the program's progress.

IFReCの大きな特徴として、その国際性があげられます。私は外国人構成員として、IFReCの発展にとって重要な意味を持つ、この研究棟の完成にあたり、お祝いの挨拶を送る機会を与えられたことを嬉しく思います。

With very best regards and wishes for continued success

皆様の今後ますますのご成功をお祈りします。

Ronald N. Germain, M.D., Ph. D.
Chief, Lymphocyte Biology Section, Laboratory of Immunology
Director, Program in Systems Immunology and Infectious Disease Modeling (PSIIM)
National Institute of Health, National Institute of Allergy and Infectious Diseases

ロナルド N. ジャーメイン
米国国立公衆衛生研究所･アレルギー感染症研究所
免疫学研究室、リンパ球生物学セクション、チーフ
システム免疫学・感染症モデリングプログラム、ディレクターMessages from Overseas Research Institutions (2)The message from Dr. Jason Cyster

The message fromDr. Ulrich H. von Andrian

Dear Professor Akira,Dear Dr. Akira,My congratulations from across thePacific to you and your colleagues on
the opening of the Integrated Life
Science Building at Osaka
University. This is an exciting moment
for Japanese immunology as the newbuilding and laboratories are certain toinvigorate the scientific collaborations
and interactions that are taking place
within the IFReC, further enabling you
to 'build' on the enormous
contributions of Dr. Kishimoto andother Japanese pioneers of themolecular immunology revolution.
I look forward to continuing
collaborative interactions with yourand other groups in IFReC and tovisiting your handsome new building
during the upcoming International
Immunology Congress.

I'm writing to express my congratulationsand very best wishes on the happy
occasion of the opening of the new
Integrated Life Science Building of IFReC
at Osaka University. Although the official
inauguration of IFReC has occurred only
relatively recently, the illustrious group ofimmunologists you have assembled in theCenter has already made an enormous
impact in many areas ofImmunology. Given its current trajectory,
IFReC is well on its way to establish itself
as a major new powerhousein international immunology. With theopening of the new research building,
IFReC investigators will have access to
cutting-edge facilities and unique
resources in a professional environmentthat fosters scientific discussion andcollegial interactions at all levels. No
doubt, this is a very positive stepthat should further boost the alreadyremarkable productivity of the Center.
Congratulations on having createdthis worldclass scientific institution!

Jason Cyster
Professor ofMicrobiology and Immunology
University of California, San Francisco

Ulrich H. von Andrian, M.D.
Mallinckrodt Professor ofImmunopathology,Harvard Medical School

The message from Dr. Fritz Melchers"The cells of the immune system can be loners who travel from the sites of
their birth in bone marrow and thymus as single cells through the blood tothe sites of their action in lymphoid organs and other places of emergencies.
In an attack against infectious invaders, allergens, tumor antigens , antigensof transplanted tissues, or sometimes even against the body's own
autoantigens they organize themselves into ordered structures, centers ofaction. After the attack the experienced cells travel again through blood andlymph vessels, now retain the memory of the system for the invader,and migrate to sites where they remain until challenged by a new invasion.
We have learned a tremendous amount of molecular and cellular facts that
describe and explain the cells of the immune system, their generation,
reaction, survival and death, and Japanese immunologists have madeoutstanding contributions to this knowledge. However, we have a very
limited knowledge of the space and time, in which all of this happens. IFReC
has been founded to investigate this spatial organization of the immune
system with the most modern methods of fluorescent microscopical imaging
in space and time, and to use the open questions of the immune system todevelop even newer methods for a deeper understanding of these dynamic
processes - in health and in diseased states of our body and our immune
system.
The building, in which IFReC is going to advance to new frontiers of ourunderstanding of the immune system is now being opened. I congratulate
Professor Tadamitsu Kishimoto for this momentous event that marks astunning success of his long efforts and dreams. I congratulate Professor
Shizuo Akira for his tireless efforts to assemble an outstanding team ofresearchers that will work in the new building, and that carry the promise of
future success and enlightenment, and I wish the team, my colleagues, all
the luck in the world to make the breakthrough discoveries that will allow us
see the immune system like never before"
Fritz Melchers
Senior Research Group Leader
Max Planck- Institute for Infection Biology