CARRICULUM VITAE
Name: Kyoko Arai
Contact Information:
School of Nursing, University of Shizuoka, Shizuoka, Japan
2-2-1, Oshika, Suruga-ku, Sizuoka-shi, Shizuoka, 422-8021, Japan
E-mail: karai@u-shizuoka-ken.ac.jp
Phone & Fax: +81-54-202-2927
Position:
Vice Dean of Nursing
Professor, School of Nursing, University of Shizuoka
Professor, Graduate school of Nursing, University of Shizuoka
Specialty:
Fundamental Nursing
Degree:1988

Diploma in Nursing (National Sanatorium Saishunso Hospital Nursing School)

2002 Bachelor of Science in Nursing (Oita University of Nursing and Health Sciences)
2006 Ph D in Human Care Science (Graduate School of Comprehensive HumanSciences, University of Tsukuba)
License:1988 RN Japanese Ministry of Health, Labor and Welfare
2002 PHN Japanese Ministry of Health, Labor and Welfare
2004 School Nurse (Ibaraki Prefecture)
Professional Experience:
2005 Assistant Professor, School of Nursing, Oita University of Nursing and HealthSciences
2006 Senior Assistant Professor, School of Nursing, Ishikawa Prefectural Nursing
University
2007 Senior Assistant Professor, School of Nursing, University of Shizuoka
2011 Associate Professor, International University of Health and Welfare GraduateSchoolPart-time Senior Assistant Professor, School of Nursing, University of Shizuoka
2014 Professor, School of Nursing, University of Shizuoka
Research：1) S Yoshida, K Hiyoshi, S Oshio, H Takano, K Takeda, T Ichinose : Effects of fetal
exposure to carbon nanoparticles on reproductive function in male offspring. Fertilityand Sterility 93（5）1695-1699, 2010.
2) S Yoshida, K Hiyoshi, T Ichinose, M Nishikawa, H Takano, I Sugawara, K Takeda :Aggravating effect of Natural sand dust on Male reproductive Function in mice.

Reproductive Medicine and Biology 8：151-156, 2009.
3) Y Totsuka, T Higuchi, T Imai, A Nishikawa, T Nohmi, T Kato, S Masuda, N Kinae, KHiyoshi, S Ogo, M Kawanishi, T Yagi, T Ichinose, N Fukumori, M Watanabe, TSugimura, K Wakabayashi : Genotoxicity of nano/microparticles in in vitro micronuclei,
in vivo comet and mutation assay systems. Particle and Fibre Toxicology 6：23, 2009.
4) T Ichinose, K Hiyoshi, S Yoshida, H Takano, M Nishikawa, I Mori, H Kawazato, AYasuda, T Shibamoto : Asian sand dust aggravates allergic rhinitis in guinea pigs
induced by Japanese ceder pollen. Inhalation Toxicology 21（12）985-993, 2009.
5) S Yoshida, K Hiyoshi, T Ichinose, H Takano, S Oshio, I Sugawara, K Takeda, TShibamoto : Effect of nanoparticles on the male reproductive system of mice.

International journal of andrology 32（4）337-342, 2009.
6) T Ichinose, S Yoshida, K Hiyoshi, K Sadakane, H Takano, M Nishikawa, I Mori, RYanagisawa, H Kawazato, A Yasuda, T Shibamoto : The effects of microbial materials
adhered to Asian sand dust on allergic lung inflammation. Archives Environmental

Contamination Toxicology 55（3）348-357, 2008.
7) AH Hashimoto, K Amanuma, K Hiyoshi, Y Sugawara, S Goto, R Yanagisawa, HTakano, K Masumura, T Nohmi, Y Aoki : Mutation in the lungs of gpt delta transgenic
mice following inhalation of diesel exhaust. Environmental and Molecular Mutagenesis
48（8）682-693, 2007.
8) K Inoue, H Takano, T Ichinose, S Tomura, R Yanagisawa, M Sakurai, D Sumi, AKCho, K Hiyoshi, Y Kumagai : Effects of naphthoquinone on airway responsiveness in thepresence or absence of antigen in the mice. Archives of Toxicology 81（8）575-581, 2007.
9) Y Aoki, AH Hashimoto, K Amanuma, M Matsumoto, K Hiyoshi, H Takano, KMasumura, K Itoh, T Nohmi, M Yamamoto : Enhanced spontaneous andbenzo(a)pyrene-induced mutation in the lung of Nrf2-deficient gpt delta mice. Cancer

Research 67（12）5643-5648, 2007.
10) K Inoue, H Takano, K Hiyoshi, T Ichinose, K Sadakane, R Yanagisawa, S Tomura, Y
Kumagai : Naphthoquinone enhances antigen-related airway inflammation inmice. TheEuropean Respiratory Journal 29（2）259-267, 2007.
11) T Ichinose, K Sadakane, H Takano, R Yanagisawa, M Nishikawa, I Mori, HKawazato, A Yasuda, K Hiyoshi, T Shibamoto : Enhancement of mite allergen-induced
eosinophil infiltration in the murine airway and local cytokine/chemokine expression by
Asian sand dust. Journal of Toxicology and Environmental Health, part A 69（16）1571-1585, 2006.
12) AH Hashimoto, K Amanuma, K Hiyoshi, H Takano, K Masumura, T Nohmi, Y Aoki :In vivo mutagenesis in the lungs of gpt-delta transgenic mice treated intratracheallywith 1,6-dinitropyrene. Environmental and Molecular Mutagenesis 47（4）277-283,2006.
13) K Hiyoshi, T Ichinose, K Sadakane, H Takano, M Nishikawa, I Mori, R Yanagisawa,S Yoshida, Y Kumagai, S Tomura, T Shibamoto : Asian sand dust enhances
ovalbumin-induced eosinophil recruitment in thealveoli and airway of mice.

Environmental Research 99（3）361-368, 2005.
14) K Hiyoshi, H Takno, K Inoue, T Ichinose, R Yanagisawa, S Tomura, Y Kumagai :Effectsofphenanthraquinone on allergic

airway inflammation in mice. Clinicaland Experimental Allergy 35（9）1243-1248, 2005.
15) AH Hashimoto, K Amanuma, K Hiyoshi, H Takano, K Masumura, T Nohmi, Y Aoki :In vivo mutagenesis induced by benzo[]pyrene instilled into the lung of gpt deltatransgenic mice. Environmental And Molecular Mutagenesis 45（5）365-373, 2005.

16) T Ichinose, M Nishikawa, H Takano, N Sera, K Sadakane, I Mori, R Yanagisawa, TOda, H Tamura, K Hiyoshi, H Quan, S Tomura, T Shibamoto : Pulumonary toxicity
induced by Intratracheal

instillation of Asian yellow dust (Kosa) in mice.

Environmental Toxicology and Pharmacology 20（1）48-56, 2005.
17) K Hiyoshi, H Takano, K Inoue, T Ichinose, R Yanagisawa, S Tomura, AK Cho, JRFroines,

Y

Kumagai :Effectsofa

singleintratracheal

administration

ofphenanthraquinone on murine lung. Journal of Applied Toxicology 25（1）47-51, 2005.
18) K Inoue, H Takano, R Yanagisawa, M Sakurai, T ichinose, K Sadakane, K Hiyoshi,
M Sato, A Shimada, M Inoue, T Yoshikawa : Role of metallothionein in antigen-related
airway inflammation. Experimental Biology and Medicine 230（1）75-81, 2005.
19) S Baba, N Osakabe, M Natsume, A Yasuda, Y Muto, K Hiyoshi, H Takano,TYoshikawa, J Terao. Absorption, metabolism, degradation and urinary excretion ofrosmarinic acid after

intake of Perilla frutescens extract in humans. European

Journal of Nutrition 44（1）1-9, 2005.