JAPANESE SOCIETY OF VASCULAR COGNITIVE IMPAIRMENT（2016 No.3）

Vas-Cog Journal

No.3

Oct 27．2016

Official Journal of Vas-Cog Japan SocietyVas-Cog Japan 2016（August 6, Kanazawa）（group photo）

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ISSN : 24239372

JAPANESE SOCIETY OF VASCULAR COGNITIVE IMPAIRMENT（2016 No.3）

Greetings from Vas-Cog Japan society
Koji Abe, MD, PhD（President）
After establishment on 2010, Vas-Cog Japan

active members, which is going to be held insociety developed year by year for elucidating

Nanjing (China) on October 26, 2017 as Vas-Cog

vascular contribution to Alzheimer's disease (AD)Asia 6.

and vascular dementia. Even during this 1 year,

Vas-Cog Japan society is dedicated to elucidate

our society kept developing with Vas-Cog Journal

the mechanism of vascular factors on any types

publication, 143 active members with 54 council

of dementia, and to contribute potential therapy

members, and 26 directors. Based on the greatfor dementia people. Many vascular risk factors

contributions of Professors Urakami K, Hanyu H,(VRFs) are related to cerebral white matter lesion

Shoji M, and Morishita R, we are going well for(WML). Because recent study suggested that age-stronger society, promotion, journal publication,dependent cognitive decline of AD is strongly

and finance. I greatly thank all of our members,

related to the age-dependent worsening of WML

councils, and directors.

(Tokuchi R et al., JNS 2016; 365: 3-8), we will

Year 2016 was memorable with the great

continue to investigate vascular and other risk

success of Vas-Cog Japan 7th meeting held in thefactors both for preventing and treating AD andbeautiful Kanazawa city organized by Professors

other dementias. I hope you to actively join ourHoriuchi M and Yamada M with more than 150

society for fighting against dementia in aged

participants. Vas-Cog Japan 8th meeting willsocieties.

be held in Tokyo by Professors Uchiyama S

August 15, 2016

and Komuro I. I would like also to celebrate thesuccess of Vas-Cog Asia 5, which was held in
Brisbane on July 14 (2016) always jointing AsiaPacific Stroke Conference (APSC). Vas-Cog Asia
is a formal society with 30 organizers and many2

JAPANESE SOCIETY OF VASCULAR COGNITIVE IMPAIRMENT（2016 No.3）

Reports of Vas-Cog Japan 2016
Masatsugu Horiuchi, MD, PhD
Ehime University
Dear Colleagues and Friends,and instructive for us. In the symposium,distinguished speakers discuss about their

The 7th Vas-Cog Japan was held at Kanazawa

excellent research results regarding life-style

Miyako Hotel in Ishikawa on August 6, 2016.

related disease-induced dementia and imaging ofDr. Yamada in Kanazawa University and I

CAA and CAA-related inflammation.

organized this year's conference. The conference

After the conference, participants enjoyed thewas greatly successful with 160 participants fromclosing party and a ceremony for awarded young

all over the country.

speakers. Finally, Dr. Uchiyama in Sannou

The main theme of this conference is

Hospital introduced the next Vas-Cog Japan“Cardiovascular disease and metabolic disorder-

meeting held in Tokyo. During the party, we

induced dementia and cerebral amyloid

also enjoyed to see fireworks performed nearangiopathy (CAA)”. The conference was

Kanazawa city through the window. We greatly

included 2 special lectures, 2 educational lectures

appreciate all the participants for the contribution

and 2 symposiums with 3 or 4 speakers. 37

to the success of the conference.

abstracts were accepted for general subjects(The article is written by Dr. Masaki Mogi)

including 12 abstracts for the young investigator
award (YIA). Three young speakers won the best
YIA after careful consideration.
The first special lecture was presented by Prof.
Minamino from Niigata University. He talked
about“The cardiometabolic network regulatedby senescent signaling”. The second lecture
was presented by Prof. James AR Nicoll from
University of Southampton. He talked about“The role of vascular system in dementia”.
He demonstrated the Amyloid Related Imaging
Abnormalities (ARIA) induced by amyloid
β vaccine therapy. Two educational lectures
included the past, current and future of vasculardementia, and imaging on dementia with Lewybodies. These lectures were highly valuable
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JAPANESE SOCIETY OF VASCULAR COGNITIVE IMPAIRMENT（2016 No.3）

After the Vas-Cog Japan 2016
Masahito Yamada, MD, PhD
Kanazawa University
We successfully finished the Vas-Cog Japan

many discussions in the sections of the symposia.

2016 at the Kanazawa Miyako Hotel on August

Furthermore, poster presenters and delegates

6, 2016, comprising of the educational lectures,

discussed fruitfully during the poster discussion

symposia, poster presentations, special lectures,session. Among 12 candidates, 4 presentations

and sponsored seminars. This is the first occasion

were chosen as Young Investigator Award (YIA).

that the meeting is held in the local city otherWe sincerely thank all members of the Ehime

than Tokyo or Kyoto since the Society has been

and Kanazawa universities for their cooperation

established in 2010. A hundred sixty delegates,

and all the participants for their contributions toincluding researchers, trainee doctors, andthe conference.

medical students, participated in the meeting tohave fruitful discussions.
In the Vas-Cog Japan 2016, we have decided“Cardiovascular and metabolic disorders anddementia, and cerebral amyloid angiopathy(CAA)”as a theme. Professor Toru Minamino at
Niigata University and Professor James Nicoll at
the University of Southampton gave us splendid
special lectures regarding relationship between
vascular system and dementia. There were also4

JAPANESE SOCIETY OF VASCULAR COGNITIVE IMPAIRMENT（2016 No.3）

An impression on Vas-Cog Asia
～ Meeting report of Vas-Cog Asia 5 from Brisbane ～Koji Abe, MD, PhD (Vas-Cog Asia President)
I would like to celebrate the great success of
Vas-Cog Asia 5, which was held in Brisbane

society in Asia. World Stroke Society (WSO)
proclaimed on the World Stroke Day that strokeon July 14 afternoon (2016) always jointing
with Asia-Pacific Stroke Conference (APSC).

and potentially preventable dementia is importantto prevent, identify, and treat, because 80% of

We had 35 participants from Japan, Taiwan,Korea, China, Hong-Kong, Malaysia, Indonesia

AD now carry vascular component.
Vas-Cog Asia society is a formal society withand Australia. There were variety of importantpresentations in the present conference. Manybasic science, translational research, clinical
trials and evidence were discussed especiallyon the aspects of Alzheimer's disease (AD),vascular dementia (VD), and their importantvascular involvement. In the Young Flash Talks
session, young Asian researchers from Japan and
China presented pretty nice talks, which weresuccessfully congratulated.
Dementia and stroke are two major
neurologically disabling diseases, and are now
closely related each other in rapidly ageing ourAsian societies. Therefore, this Vas-Cog Asia
will become more important meeting and the23 directors from most Asian countries andmany active members, which is dedicated toelucidate such a mechanism of vascular factors
on any types of dementia, and to contributepotential therapy for dementia people in Asia.
Many vascular risk factors (VRFs) are related tocognitive decline and affective-emotional changes
in dementia patients. Next Vas-Cog Asia is going
to be held in Nanjing (China) on October 26,
2017 as Vas-Cog Asia 6. All of you are welcome
to actively join this forthcoming meeting topresent and discuss on vascular factors of all typedementia.
August 15, 2016

5JAPANESE SOCIETY OF VASCULAR COGNITIVE IMPAIRMENT（2016 No.3）

Welcome to Vas-Cog Japan 2017

Shinichiro Uchiyama, MD, PhD

Issei Komuro, MD, PhD

International University of Health and Walfare /Sanno Hospital and Sanno Medical Center

The University of Tokyo

We planned to hold the Vas-Cog Japan 2017 onand cognitive impairment in this meeting. We are

August 5 in Tokyo. The number of participants isplanning lectures and symposia which meet thesegrowing along with the increase of patients withhighlights, as well as oral and poster sessions forcognitive impairment. The topic of this meeting

young investigators. We are pleased to do ouris“Cognitive Impairment from Aspect of Organ

best for you to enjoy and satisfy this meeting.

Linkage”. According to the recent knowledge,

The Venue Toranomon Hills building is a

all major dementia have a vascular component

new popular facility, which is closely locatedincluding 80% in Alzheimer's disease. Silentto Ginza, and easily connects to Shinjuku or

strokes occur 5 times as often as clinical strokes,

Shibuya Station. There are many new restaurants

and may affect memory, behavior, mood, andand shops around this area. There would be many

personality. Additionally, heart diseases such as

midsummer events as well.
We hope to have many abstracts and delegates.

heart failure and atrial fibrillation have recently

Please join this meeting. All of you are very

been recognized to affect cognitive function.

welcome.

Disruption of neurovascular units associatedwith impairment of brain microcirculation, which
is promoted by vascular components, is muchargued as a mechanism of Alzheimer's disease.
Imaging markers for cognitive decline arerecently focused on cerebral microbleeds, cortical
microinfarcts, widening of vascular spaces,
superficial siderosis, and cortical thinning inaddition to classical markers such as silent brain
infarcts and subcortical white matter lesions.
Based on these backgrounds, we would like towidely discuss about the relationships between
disturbance of systemic organs or blood vessels
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JAPANESE SOCIETY OF VASCULAR COGNITIVE IMPAIRMENT（2016 No.3）
VAS-COG 2017

A2 ポスター420×594mm

20150910

2017
第 8 回日本脳血管・認知症学会総会

8th Annual Meeting of the JapaneseSociety for Vascular Cognitive Impairment
http://www.conet-cap.jp/vas-cogj/

VAS-COG J

臓器連関から考える認知機能障害
日時
場所

2017年
（土）
年8月月5日日（土）
虎ノ門ヒルズフォーラム〒105-6305 東京都港区虎ノ門1-23-3 虎ノ門ヒルズ森タワー4階
2017

演題登録期間3月

201715日

4月

（水）

（月）

真一郎

国際医療福祉大学臨床医学研究センター/山王病院・山王メディカルセンター 脳血管センター

APAN 20
1
YO
TOK

VAS

J
OG

長： 内山

7-C会

17日

小室一成

東京大学大学院医学系研究科 循環器内科学

VAS-COG J

副会長： 北川一夫

東京女子医科大学医学部 神経内科
総会事務局

運営事務局

〒162-8666
東京都新宿区河田町8-1
東京女子医科大学医学部 神経内科
事務局長：吉澤 浩志（講師）〒532-0004
大阪府大阪市淀川区西宮原1-8-29テラサキ第2ビル 株式会社コネット
TEL：0 6 - 6 3 9 8 - 5 7 4 5 FAX：06-6398-5746
E-mail：vas-cogj@conet-cap.jp

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JAPANESE SOCIETY OF VASCULAR COGNITIVE IMPAIRMENT（2016 No.3）

Reports of Vas-Cog Japan Council Meeting
Ryuichi Morishita, MD, PhD
Osaka University
The 8th board member and council meeting for Japan
Vas-Cog was held together on the 8th of August,2016 in Kanazawa at the Miyako Hotel, with 19 board
members and 25 councilors in attendance.

*The chairperson of financial affairs, Dr. RyuichiMorishita, reported on the financial accounting anddiscussed the bank account balance of JPY210,000
at the end of March 2016. In 2015, income was
JPY670,000 and outgoing was JPY1,400,000. In thisperiod, there was more outgoing, however, we havecontributions from Vas-Cog J 2015 of a little under
JPY500,000 and from Vas-Cog World of a little morethan JPY3,500,000. We assume this year's operations
will go smoothly. We would like to ask for paymentof membership fees, for those who have yet to pay.
Auditing will be Dr. Matsubara and Dr. Morishita.
Next year, we will ask Dr. Shimamura and one otherperson. We are unable to have president act as auditor
for an incorporated association.

The President and members reported on and approved
the topics below.
[ Membership ] 143 regular members (31st July 2016)[Report from each chairman]*The chairperson for the promotion of becoming
a society, Dr. Katsuya Urakami, discussed thedifficulties of forming a society.
We must have the researcher number of grants‐in‐aid for scientific research and must have over 100
members without nonpayment of membership fees.
We would like to ask for cooperation with payment ofmembership dues.

[Plans for future meetings]
1. The 8th Meeting (August 5th, 2017: ToranomonHills, Tokyo)
Organizers: Dr. Shinichiro Uchiyama, Dr. Issei
Komuro, and Vice-Chairperson Dr. Kazuo Kitagawa*The chairperson for increasing membership andpublic relations, Dr. Haruo Hanyu, discussed increasing
supporting memberships.
We created space for six homepage banneradvertisements. At the moment, we have four spaces
vacant, and would like to ask for your cooperation inasking more companies.

2. Vas-Cog Asia 2017（October 26 (Thu) 2017,Nanjing）
3. The 9th Meeting (2018)
Organizers: Dr. Katsuya Urakami and Dr. Etsuro
Matsubara*The chief editor of the academic magazine, Dr. Mikio
Shoji, discussed selecting a person to be in charge fora third volume of the periodical, which will be mailedin November.
The president reported at the Vas-Cog Asia board
meeting that since there is no journal for Asia, it will
be combined with the Japan Journal. In the future, weare aiming to receive an Asian journal circular.

4. The 10th Meeting (2019)
Organizers: Dr. Masahiro Akishita and Dr. YoshioIkeda
See homepage for further plans[Report of new board members / councilors]* indicates board member or councilor
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JAPANESE SOCIETY OF VASCULAR COGNITIVE IMPAIRMENT（2016 No.3）[Name list]● Executive Advisor
Hiroshi Mori (Osaka City University)● President● Secretary General

Koji Abe (Okayama University)

Ryuichi Morishita (Osaka University)● Executive Directors
Masahiro Akishita (The University of Tokyo)

Yoshio Ikeda (Gunma University)

Shinichiro Uchiyama

Katuya Urakami (Tottori University)(International University of Health and Welfare)Nobuya Kawabata (Yachiyo Hospital)

Kazuo Kitagawa (Tokyo Women's Medical University)

Koichi Kozaki (Kyorin University)

Issei Komuro (The University of Tokyo)

Masataka Sata (Tokushima University)

Mikio Shoji (Hirosaki University)

Masahiko Suzuki

Syunya Takizawa (Tokai University)(The Jikei University School of Medicine)
Yasuo Terayama (Iwate Medical University)

Hidekazu Tomimoto (Mie University)

Ken Nagata

Haruo Hanyu (Tokyo Medical University)(Research Institute for Brain and Blood Vessels)
Toshiya Fukui (Kawasaki Memorial Hospital)

Masatsugu Horiuchi (Ehime University)

Etsuro Matsubara (Oita University)

Toshiki Mizuno(Kyoto Prefectural University of Medicine)

Shokei Mitsuyama (Kumamoto University)

Masaru Mimura (Keio University)

Shuhei Yamaguchi (Shimane University)

Masahito Yamada (Kanazawa University)● Auditors
Munehisa Shimamura (Osaka University)

Miyuki Matsumura(Institute of Geriatrics
Tokyo Women's Medical University)

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JAPANESE SOCIETY OF VASCULAR COGNITIVE IMPAIRMENT（2016 No.3）● Councilors
Hitoshi Aizawa (Tokyo Medical University)

Yasuhiro Aso (Oita University Hospital)

Satoshi Abe (Shimane University Hospital)

Masaki Ikeda (Gunma University Hospital)

Nobuyoshi Ishii (Oita University)

Hiroo Ichikawa (Showa University Fujigaoka Hospital )Masafumi Ihara(National Cerebral and Cardiovascular Center)

Jun Iwanami (Ehime University)

Yumiko Uchiyama(Tokyo Women's Medical University)

Takao Urabe (Juntendo University Urayasu Hospital)

Yasuyuki Ohta (Okayama University)

Sumito Ogawa (The University of Tokyo)

Hiroaki Oguro (Shimane University Hospital)

Kenjiro Ono (Showa University)

Haruhisa Kato (Tokyo Medical University)

Tatsushi Kamiya (Kamiya Clinic)

Yumi Kameyama (The University of Tokyo Hospital)

Noriyuki Kimura (Oita University)

Hitomi Kurinami (Osaka University)

Minoru Kouzuki (Tottori University)

Taro Kojima (The University of Tokyo)

Masaki Kondo(Kyoto Prefectural University of Medicine)

Kenji Sakai (Kanazawa University Hospital)

Hirofumi Sakurai (Tokyo Medical University)

Naoyuki Sato (Osaka University)

Masayuki Satoh (Mie University )Yoshiki Takao (Kurashiki Heisei Hospital)

Daiki Takano (Yokohama General Hospital)

Ayumi Takamura (Tottori University)

Shuko Takeda (Osaka University) ※Yasushi Takeya (Osaka University)

Kentarou Deguchi (Okayama University)

Hiroo Terashi (Tokyo Medical University)

Takashi Tokashiki (University of the Ryukyus)

Takahiko Tokuda(Kyoto Prefectural University of Medicine)

Kazuaki Nagashima (Gunma University)

Masao Nagayama (IUHW Atami Hospital)

Yu Hasegawa (Kumamoto University)

Yasuto Higashi (Himeji Central Hospital)

Yukihito Higashi ※(Research Institute for Radiation Biology and Medicine)

Nozomi Hishikawa (Okayama University)

Yukio Fujita (Gunma University)

Kouki Makioka (Gunma University Hospital)

Yasuhiro Manabe(National Hospital Organization Okayama Medical Center)

Toru Minamino (Niigata University) ※Min Rijuan (Ehime University) ※Kazuhiro Muramatsu(Tokyo Dental College Ichikawa General Hospital)

Kenichi Meguro (Tohoku University)

Masaki Mogi (Ehime University)

Hideki Mochizuki (Osaka University)

Takashi Yamazaki(Research Institute for Brain and Blood Vessels-Akita)

Toru Yamashita (Okayama University Hospital)

Hiroshi Yoshizawa(Tokyo Women's Medical University) ※Kouji Wakayama (The University of Tokyo)

Yosuke Wakutani (Kurashiki Heisei Hospital)

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JAPANESE SOCIETY OF VASCULAR COGNITIVE IMPAIRMENT（2016 No.3）

Editor's Note
Mikio Shoji MD, PhD.
Hirosaki University
Here we bring you the 3rd issue of Vas-doctors and researches including many young

Cog Journal. The 7th meeting, Vas-Cog Japan

investigates joined the meeting. I deeply

2016, hosted by Dr. Masatsugu Horiuchi in

impressed the developing of this field and ourEhime University, and Dr. Masahiko Yamada

society. Society office well supported agenda,

in Kanazawa University at Kanazawa Miyako

and new participation of board and councilor

Hotel in August 6 2016. In this issue, topics

members were selected for the next Vas-Cogfrom the meeting were featured. Dr. Nicoll fromsociety. International network is now developing

Southampton University delivered invitation

with Vas-Cog World and Vas-Cog Asia. We arelecture. Two symposiums, 2 lectures, 37 poster

looking forward to manuscript publication in thepresentations and lively discussion were allnext issue, and hope Japanese society and Journal

higher level and impressive. More than 160

could contribute further in this world wide field.

The past and future annual meeting of Vas-Cog JapanThe 1 st Meeting : August, 2010 (Tokyo) Chairman : Ken Nagata and Toshiya Fukui
The 2nd Meeting : August, 2011 (Tokyo) Chairman : Koji Abe and Shokei Mitsuyama
The 3 rd Meeting : August, 2012 (Tokyo) Chairman : Ryuichi Morishita, Yasuo Terayama, and Koji Abe
The 4 th Meeting : August, 2013 (Tokyo) Chairman : Mikio Shoji and Haruo Hanyu
The 5 th Meeting : August, 2014 (Kyoto) Chairman : Toshiki Mizuno and Hidekazu Tomimoto
The 6 th Meeting : August, 2015 (Tokyo) Chairman : Shinya Kawabata and Shuhei Yamaguchi
The 7 th Meeting : August, 2016 (Kanazawa) Chairman : Masatsugu Horiuchi and Masahito Yamada
The 8 th Meeting : August, 2017 (Tokyo) Chairman :Shinichiro Uchiyama and Issei Komuro
The 9 th Meeting : August, 2018 (Beppu) Chairman : Katsuya Urakami and Etsuro Matsubara
The 10th Meeting : August, 2019 (Tokyo) Chairman : Masahiro Akishita and Yoshio Ikeda
The 11th Meeting : August, 2020 (planned) Chairman : Shunya Takizawa and Masataka Sata
The 12th Meeting : August, 2021 (planned) Chairman : Kazuo Kitagawa and Koichi Kozaki
The 13th Meeting : August, 2022 (planned) Chairman : Masahiko Suzuki- to be continued -11