2019 Feb CU-UCSD cMAV Symposium Agenda Plan C.docx
Day 1: Wed.,February 13,
20198:00 AM
8:30 AM

8:45 AM
9:15 AM
9:45 AM
10:15 AM
10:30 AM *Upper Auditorium
MET Building
Coffee and morning snacks for the early birds
Welcoming remarks
David Brenner and Toshinori Nakayama
Session 1: Mucosal Immunology: Mucosal Homeostasis
Chairs: Hiutung Chu and Hiroshi Kiyono“Roles of Fucosyltransferase 2 in House Dust Mite-Induced Airway Inflammation”
Hiroshi Nakajima: Department of Allergy and Clinical Immunology, Graduate Schoolof Medicine, Chiba University, Japan and CU-UCSD cMAV, UCSD
“Evasion of IL-22-mediated Antimicrobial Responses by Bacterial Pathogens”
Manuela Raffatellu: Department of Pediatrics, UCSD and CU-UCSD cMAV, UCSD
“Mechanisms Controlling Innate Immune Response to Nucleic Acids”
Kensuke Miyake: Division of Innate Immunity, The Institute of Medical Science, The
University of Tokyo
Coffee Break

2:15 PM *Yosuke Kurashima: Department of Innovative Medicine, Graduate School ofMedicine, Chiba University and CU-UCSD cMAV, UCSD.
“The Role of the Immune System in Regulating the Microbiota-gut-brain Axis”
Melanie Gareau: Department of Anatomy, Physiology and Cell Biology, School ofVeterinary Medicine, UC Davis
TBA for young investigator
Hilde Cheroutre: Division of Developmental Immunology, La Jolla Institute for Allergyand Immunology., San Diego CA
Lunch Provided for Registered Attendees(Posters Up for Viewing)
Session 2: Mucosal immunology gone wrong: IBD
Chairs: Peter Ernst and Shimon Sakaguchi“Crohn’s Disease – Defining Risk in Healthy First Degree Relatives in GEM Project”
Ken Croitoru: Mount Sinai Hospital, Zane Cohen Centre for Digestive Diseases,
Toronto Canada“Using Single-Cell Approaches to Elucidate Mucosal Immune Responses”
John Chang: Division of Gastroenterology, Department of Medicine, UCSD
Hiutung Chu: Department of Pathology, UCSD and CU-UCSD cMAV, UCSD

2:45 PM *Daisuke Tokuhara, CU-UCSD, cMAV, UC San Diego.

3:05 PMCoffee Break

3:20 PM“RNA Binding Proteins Control Intestine Homeostasis and Diseases”
Wendy Huang: Department of Cellular and Molecular Medicine, UCSD
“B Cells Responses in Inflammatory Bowel Disease”
Jesus Rivera-Nieves: Division of Gastroenterology, Department of Medicine, UCSD
“Translational Regulation of Memory CD8 T Cell Differentiation”
Koichi Araki, Department of Microbiology and Immunology, Emory University Schoolof Medicine
Keynote Speaker 1: Shimon Sakaguchi, Osaka, Japan
Advisory Board Meeting
Speakers and Advisory Board Dinner @ La Jolla Shores Hotel

10:50 AM
11:20 AM
11:40 AM *12:10 PM

1:15 PM
1:45 PM

3:50 PM
4:20 PM
4:40 PM
5:30 PM
7:00 PMDay 2: Thurs.,
February 14,
2019

Upper Auditorium
MET Building

9:30 AM

Session 3: Allergy and Inflammation -1
Chairs: Steve Hedrick and Yumi Matsuoka
Coffee and morning snacks for the early birds“Memory-Type Pathogenic Th2 Cells (Tpath2 Cells) in Airway Inflammation”
Toshinori Nakayama: Dean Graduate School of Medicine, Chiba University, Chiba
Japan and CU-USD cMAV, UCSD
“Intestinal Bacteria Regulate Allergic Responses to Food”
Cathy Nagler: Department of Pathology, University of Chicago, Chicago, IL.
Peter Ernst: Department of Pathology, UCSD and CU-UCSD cMAV, UCSD

10:00 AM

Coffee Break

10:15 AM

“CD69 Regulates T Cell Exhaustion at the Tumor Microenvironment”
Motoko Kimura, Department of Immunology, Graduate School of Medicine, Chiba
University“Therapeutic Modulation of IgE in Patients Reveals Critical Pathogenic Roles for IgE”
Dale Umetsu: Principle Medical Director, Genentech.
“Regulation of ILC2s in the Lungs and Adipose Tissue”
Omid Akbari: Department of Molecular Microbiology and Immunology, USC“Chromosome 17q21 and Asthma”
David Broide: Department of Medicine, UCSD
“Novel Innate Immune Pathways Protecting the Lung From Bacterial Pathogens”
Mitchell Kronenberg: Division of Developmental Immunology, La Jolla Institute forAllergy and Immunology., San Diego CA

8:00 AM
8:30 AM
9:00 AM

10:35 AM
11:05 AM
11:55 AM
12:05 AM
12:35 PM

1:35 PM
1:55 PM
2:25 PM

2:55 PM
3:25 PM
3:40 PM
4:00 PM
4:30 PM

Lunch Provided for Registered Attendees(Posters Up for Viewing)
Session 4: Allergy and Inflammation - 2Chairs: David Broide and Yosuke Kurashima“Establishment of Lung-Resident CD8 T Cell Memory”
Shiki Takamura, Department of Immunology, Graduate School of Medicine, Chiba
University“Regulation of Type-2 Inflammation”
Steven Ziegler: Benaroya Research Institute, Seattle, WA. Move to earlier slot? Dr.
Ziegler departing Thurs. 2/14 afternoon“Mechanisms and Clinical Impacts of Esophageal Remodeling in Eosinophilic
Esophagitis”
Seema Aceves: Division of Rheumatology, Allergy and Immunology, Department ofMedicine, UCSD
“Microbial and Vaccine-mediated Regulation of the Developing Immune System”
Damon Tumes: Allergy and Cancer Immunology Laboratory,
Centre for Cancer Biology SA Pathology and University of South Australia
Coffee Break“Tissue Remodeling Fibrosis in Mucosal Sites of the Airway”
Kiyoshi Hirahara, Department of Immunology, Graduate School of Medicine, Chiba
University“Germinal Center and the Broadly Protective Antibody to Influenza”
Masato Kubo: Division of Molecular Pathology, Research Institute for BiomedicalScience, Tokyo University of Science, Chiba, Japan“Staphylococcus Agar Virulence is Critical for Skin Colonization and Associated withAtopic Dermatitis Development”
Yumi Matsuoka-Nakamura: Department of Dermatology, Graduate School ofMedicine, Chiba University, Japan

4:50PM
5:20 PM“Effect of Allergen-Specific Immunotherapy on Human CD4+ T Cells”
Eric Wambre: Translational Research Program, Benaroya Research Institute,Seattle, WA
Session 4. Poster Session / Buffet Style Reception

Day 3: Fri.,
February 15,
20198:00 AM
8:30 AM

9:00 AM
9:30 AM

10:00 AM
10:15 PM
10:35 AM
11:05 AM
11:35 AM *12:05 PM

1:05 PM
1:35 PM

2:05 PM
2:35 PM2:50 PM
3:10 PM *3:40 PM
4:10 PM
4:30 AM *5:10 PM

Upper Auditorium
MET Building
Session 5: Immune Memory for Health and Diseases
Chairs: Seema Aceves and Yumiko ImaiCoffee and morning snacks for the early birds“Mechanisms for Memory B-Cell Formation and Function: Possible Implications for
Vaccination”
Daisuke Kitamura: Division of Molecular Biology, Research Institute for Biomedical
Science, Tokyo University of Science, Chiba, Japan“The Role of CCR5-expressing Cells in Gut Homeostasis”
Steve Hedrick: Division of Biological Sciences, Section of Molecular Biology, UCSD
“Salmonella SiiE Prevents an Efficient Humoral Immune Response by Interfacingwith IgG-secreting Plasma Cell Persistence in the Bone Marrow”
Koji Tokoyoda: Division of Osteoimmunology, Deutsches RheumaForschungszentrum Berlin, Germany
Coffee BreakYoung Investigator TBA“Regulation of Immunoglobin Class Switch and Autoimmunity”
Koji Yasutomo: Department of Immunology and Parasitology, Graduate School ofMedicine, Tokushima University, Japan“Adaptions During Long-Term (Host-Pathogen) Relationships”
Elina Zuniga: Division of Biological Sciences, Section of Molecular Biology, UCSDDavid Broide: Department of Medicine, UCSD

Lunch Provided for Registered Attendees(Posters Up for Viewing)
Session 6: Mucosal Immunity and Vaccine
Chairs: Manuela Raffatellu and Masato Kubo
Ken Ishii: Center for Vaccine and Adjuvant Research, National Institutes ofBiomedical Innovation, Health and Nutrition, Osaka, Japan“Stimulation of Mucosal CD8+ T Cells as an Alternate Strategy for Rendering
Protection against Brucellosis”
David Pascual: Department of Infectious Diseases, College of Veterinary Medicine,
University of Florida, Gainesville Florida
Hiroshi Kiyono: University of Tokyo and Chiba University, Japan and Division ofGastroenterology, CU-UCSD, cMAV, UC San Diego.” Development of novel oralvaccines for global health"Coffee BreakYumiko Imai, Laboratory of Regulation of intractable Infectious Disease, NationalInstitutes of Biomedical Innovation, Health and Nutrition, Osaka, Japan“A Human Immune System Mouse Model for Vaccine/Adjuvant Research”
Moriya Tsuji, Aaron Diamond AIDS Research Center, NY
Young Investigator TBA
Sujan Shresta: Center for Infectious Diseases, La Jolla Institute for Allergy andImmunology Move to Wed. 2/13 or Thurs. 2/14 – not available Fri. 2/15
Poster Awards and Closing Ceremony

Speakers tentatively confirmedSpeakers need to be confirmed
Speaker confirmed lecture
If someone we need to invite for cMAV, the slots can be used for new speakers
Young Investigators* Tentative/to be determined Lecture Title

TY sponsors
Kyowa Kirin Pharmaceutical Research represented by Kiyoshi Mori
Takeda, Tcal, represented by Laurens Kruidenier and Ewan Taylor
Andrea Jefferson, Nancy Clemens
UCSD, LJI Immunology Program
IIMVF, International Immunology Memory and Vaccine ForumToshinori Nakayama and colleagues at Chiba University
US Japan Program in Immunology