The 2 nd Symposium of International
Immunological Memory and Vaccine Forum (IIMVF)

Trends in
Immunological Memory andVaccine Development

August 25-26, 2014
La Jolla Institute of Allergy & Immunology
La Jolla, California, U.S.A.

Organized byInternational Immunological Memory and Vaccine Forum
US-Japan Cooperative Medical Sciences Program on Immunology
La Jolla Institute for Allergy & Immunology
Leading Graduate School at Chiba University
Chiba Innovation Program for Therapeutics at Chiba University	  ~Program~
Monday, August 25
9:00

Arrival

9:00-9:10

Welcoming Remarks

Session I

Mucosal immunology (Chair H. Kiyono/K. Takeda)

9:10-9:40

Toshinori Nakayama “Pathogenic Memory Th2 Cells in theairway”

9:40-9:55

Masaki Miyazaki “Id2 and Id3 maintain the regulatory T cellpool to suppress Th2 inflammatory disease”

9:55-10:25

Mitchell Kronenberg “Mechanisms for the regulation ofmucosal immunity by the herpes virus entry mediator"

10:25-11:00

Coffee Break

11:00-11:30

Kiyoshi Takeda “Regulatory mechanisms of gut homeostasis”

11:30-11:45

Yujun Huang "Driving pre-existing immunity at the mucosalborders of the intestine”

11:45-12:00

Satoshi Uematsu “Blockade of TLR3 protects mice fromlethal radiation-induced gastrointestinal syndrome”

12:00-1:30

Lunch and Poster Session

Session IICD4 T cells (Chair: Shane Crotty)

1:30-2:00

Sonoko Habu “The in vitro induction of serial transfer ofanergy status: a model for long lasting immune tolerance”

2:00-2:15

Takanori So “A novel molecular function of TRAF5 in CD4 T
cell lineage commitment ”

2:15-2:30

Koji Tokoyoda “Resting T helper cell memory in bonemarrow”

2:30-3:00

Shane Crotty “Genetics of Tfh differentiation”

	  3:00-3:15

Norifumi Iijima “A local chemokine network sustains tissueresident memory T cells crucial for antiviral protection”

3:15-3:45

Coffee BreakSession III

CD8 T cells (Chair: Alex Sette)

3:45-4:15

Alex Sette “Comparative analysis of human T cell
responses to DENV and TB”

4:15-4:30

Makoto Kurachi “The transcription factor BATF operates as
an essential differentiation checkpoint in early effector CD8+
T cells

4:30-4:45

Shiki Takamura “CD69 controls a balance between S1Pand CXCL16-mediated chemotaxis in the establishment ofCD8+ T cell memory in the lung airways”

4:45-5:00

Patrick Metz “Regulation of Asymmetric Division and CD8+
T Lymphocyte Fate Specification by PKCζ and PKCλ/ι”

5:00-5:30

Louis Picker “The Unique Immunobiology of Cytomegalovirus
Vectors; New Immunology from a Very Old Virus”

5:30

Adjourn for the day

Tuesday, August 26
Session IV

Vaccines 1 (Chair: Ken Ishii)

9:00-9:30

Hiroshi Kiyono “Mucosal immunity and vaccine development”

9:30-10:00

Bali Pulendran “Systems Vaccinology: enabling rational
vaccine design with systems biology”

10:00-10:30

Ken J Ishii “Innovation and renovation of vaccine adjuvant”

10:30-11:00

Coffee BreakSession V

Novel regulatory pathways (Chair: Erika Pearce)

11:00-11:30

Erika Pearce “Metabolic interactions in the tumor
microenvironment”

	  11:30-11:45

Wataru Ise “Regulation of germinal center response by thetranscription factor BATF”

11:45 -12:15

Masato Kubo “Notch regulates reciprocal expression ofCCR7 versus CXCR5 to control central memory T cell
generation”

12:15 -12:30

Kiyoshi Hirahara “Asymmetry of STAT action to define
specificity and redundancy of IL-27 and IL-6 signals”

12:30-1:30

Lunch

Session VI

B cells (Chair: Tomohiro Kurosaki)

1:30-2:00

Tomohiro Kurosaki “Mechanisms underlying rapid memory
IgG responses”

2:00-2:30

Daisuke Kitamura “Molecular mechanisms for thedevelopment of B-cell memory”

2:30-3:00

Nobuo Sakaguchi “Role of GANP in the DNA repair for AIDinduced somatic hypermutation generating high affinity
antibodies”

3:00-3:30

Coffee BreakSession VIIVaccines 2 (Chair: Hiroshi Kiyono)

3:30-3:45

Klaus Ley “Protective Autoimmunity in Atherosclerosis”

3:45-4:15

Uli von Andrian “A mucosal vaccine against Chlamydia
trachomatis generates two synergistic waves of protective
memory T cells”

4:15-4:30

Raphael Zellweger “Importance of CD8 T cells forprotection against heterotypic Dengue virus infection andantibody-mediated severe disease”

4:30-4:45

Sunnie Yoh “PQBP1 is an innate immune receptor for HIV-1”

4:45-5:15

Dennis Burton “HIV vaccine targets identified by broadly
neutralizing antibodies”

5:15-5:30

Closing remarks

5:30-6:45

Refreshments

International Immunological Memory and Vaccine Forum

Inquiries

Administrative OfficeTel: +81 43-226-2185
E-mail: hseo@chiba-u.jp

Fax: +81 43-227-1498