June 21, 2024
Eisai Co., Ltd.

No. 24-43

EISAI CONTINUES CONTRACT FOR FY2024 DEMENTIA EXAMINATION PROJECTBY TOKYO BUNKYO CITY
ACHIEVEMENT OF OUTCOME INDICATORS IN FY2023 PAY FOR SUCCESSCONTRACT
Eisai Co., Ltd. (Headquarters: Tokyo, CEO: Haruo Naito, “Eisai”) announced today that the company has
achieved the pre-set performance indicators in FY2023 for the dementia examination project in Bunkyo
City, Tokyo, which the company has been commissioned to conduct in order to raise awareness ofdementia and promote early detection, and will continue the commission for this project in FY2024.
This project is a dementia examination program targeting approximately 12,300 Bunkyo City residents
between the ages of 55 and 75, at a milestone of every 5 years. Brain health is checked using “NouKNOW®”(pronounced “NOH-NOH”), a digital tool for self-assessment of cognitive function, and based on theassessment results as well as a medical interview, physicians will provide medical advice or referrals tomedical institutions. The project also introduces support available from visiting nurses, and encourages
participation in lifestyle improvement programs. Since early detection and response to dementia isimportant, Tokyo is recommending that the target age group for dementia examination be expanded fromthe current age of 70 and over to 50 and over. This project, which targets 55-year-olds, is one of thepioneering examples of local government efforts toward the early detection of dementia.
The dementia examination project has been implemented since FY2021 as a priority policy of Bunkyo City,
and Eisai has been commissioned for the project since it’s launch, providing NouKNOW and operational
support for their public examinations. In FY2022, a Pay For Success (PFS) contract was introduced andtargets were established for the outcome indicators of number of NouKNOW checks performed andnumber of participants in lifestyle improvement programs. Eisai achieved both outcome indicators in
FY2022 and FY2023 through measures such as holding NouKNOW trial sessions and providing
opportunities to experience "Brepacise®," an exercise program developed by Eisai.
 FY2023 PFS Outcome Indicators
Performance Indicator

TargetResult

1: Brain health checks performed using NouKNOW

1,131 people 1,229 people 109%

2: Average participation in lifestyle improvement programs

41 people

43 people

Achievement %105%

In FY2023, 245 people participated in on-site examinations, of which approximately 12% led torecommendations to see a medical institution. In a survey conducted after the examination, 52% of the122 respondents said that they had developed a more positive outlook on dementia, and 68% said thatthey had become more interested in the brain and health.

Eisai has concluded regional cooperation agreements with local governments, medical associations, andother organizations throughout Japan, providing opportunities for brain health assessments tailored to local
issues and conducting initiatives to establish a pathway to subsequent medical care and support. In
FY2023, these initiatives were promoted in 60 local governments. Moving forward, Eisai will continue tocontribute to the creation of a community where local residents are aware of and check their brain healthfrom the stage where they are in a healthy condition, and where early detection, diagnosis, and preparation
for dementia are possible, aiming to realize a Dementia-Inclusive Society where people with dementia
can live their lives how they would like.

Media Inquiries:
Public Relations Department,
Eisai Co., Ltd.
+81-(0)3-3817-5120[Notes to Editors]
1. About NouKNOWNouKNOW (non-medical device) is a tool that uses a simple card test using a PC, tablet or smartphone device toperform tests evaluating psychomotor function, attention, learning and memory, and working memory. This digital
tool allows users to self-assess independently and in a short time frame (approx.15 minutes), enabling regularassessments in instances such as daily life and health checkups. It has been adopted by a number of medical andresearch institutions, local governments, corporations and universities.
For additional information, please visit https://nouknow.jp/. (Japanese only)(List of partners: https://nouknow.jp/partner/)
2. About Pay For Success (PFS)Pay For Success (PFS) is a new method of public-private partnership to set outcome indicators in accordance withthe administrative issues to be solved by the projects that local public entities, etc. contract out to private sectors for
its implementation, and the amount paid by the local public entity, etc. to the private sector for outsourcing a projectis linked to improvement of the relevant outcome indicators as evaluated by a third party. PFS is a policy promotedby the Cabinet Office of Japan, which is expected to improve the quality of public services and reduce expenditures.
3. About Brepacise
Brepacise is a dual-task exercise program that stimulates the body and brain by moving the arms and legs to music
while also incorporating intellectual challenges. Eisai developed this product with the review of a physician as aneasy and fun introductory exercise for those concerned about their brain health. It is being used in health classes
and online events run by local governments.
For additional information, please visit the dementia information site “Sodan e-65” operated by Theoria technologies
Inc., a member of Eisai Group. (https://soudan-e65.com/maintenance/brain_exercise/, Japanese only.)