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Uracil-DNA Glycosylase, Heat-labile
First issue : Oct. 2, 2018
Revised : Apr. 1, 2021
SDS No.1600F

Safety Data Sheet
1 CHEMICAL PRODUCT AND COMPANY IDENTIFICATION
Identification of the product

Uracil-DNA Glycosylase, Heat-labile

Product Code
SUPPLIER
Name
Address
Department
Emergency Telephone No.
Fax No.
Recommended use and restrictions on use

UNG-101, 109
TOYOBO Co., Ltd.
2-8 Dojima Hama 2-chome, Kita-ku OSAKA 530-8230 JAPAN
Biotechnology Overseas Sales and Marketing Department+81-6-6348-3843+81-6-6348-3833
decomposition of DNA template containing uracil (Reagent for research)

2 HAZARDS IDENTIFICATION
Important Hazards
Adverse effects on human health
GHS Classification

Few adverse human health effects are anticipated.
Not classified

3 COMPOSITION / INFORMATION ON INGREDIENTS
Chemical Product(Substance/Mixture)
Chemical Nature

MixtureAqueous solution of enzyme
Main components
Uracil DNA glycosylase
GlycerolComponents Contributing to the Hazard
Common Chemical Name
Synonyms
Chemical formula
CAS No.
Concentration

CAS No.
56-81-5Glycerol
Glycerin
CH2OHCHOHCH2OH
56-81-550%

4 FIRST-AID MEASURES
Inhalation
Skin Contact
Eye ContactIngestion

In case of irritation by inhaling this product, remove person to fresh airand keep comfortable. Seek medical attention.
Wash with clean water, immediately.
Rinse cautiously with water for several minutes. If eye irritation persists:
Get medical advice / attention.
Rinse mouth. Call a POISON CENTER or doctor/physician if you fell
unwell. Do not induce to vomiting.

5 FIRE-FIGHTING MEASURESExtinguishing MediaSpecific extinguishing methods
Protection of fire-fighters

Water, Carbon Dioxide, Foam, Dry Chemical Powder
Fire-fighting should be done from the windward side of fire area.
Fire-fighters should wear proper protective equipment in case of large
scale fire.

6 ACCIDENTAL RELEASE MEASURES
Personal precautions, protective
equipment, and emergency procedure

Wear protective equipment to avoid eye/skin contact and inhalation.

Environmental Precautions
Avoid disposition to the environment.
Methods and materials for containment
Use cloth, paper or anything similar to soak up the solution leaking out ofand methods and materials for cleaning up the container. Take up under vacuum using dust collecting filter.

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Uracil-DNA Glycosylase, Heat-labile
First issue : Oct. 2, 2018
Revised : Apr. 1, 2021
SDS No.1600F

Safety Data Sheet
7 HANDLING AND STORAGE
Handling 〈precautions for safe handling〉
Technical Measures
Precautions 〈local/total ventilation〉
Prevention of contact
Hygiene measures
Storage 〈conditions for safe storage〉
Technical Measures
Incompatible substances and mixtures
Packaging Materials

Wear protective equipments and avoid contact with eyes and skin.
Good laboratory technique should be used .
Avoid contact with oxidizers.
After handling, wash with clean
Keep tightly closed and store between -20℃ and -30℃Oxidizers
Store in the original package

8 EXPOSURE CONTROLS AND PERSONAL PROTECTION
ENGINEERING MEASURES

Control Parameter
Limit Values
JSOH OELACGIH TLVOSHA PEL
Personal protective equipment
Respiratory Protection
Hand Protection
Eye Protection
Skin and Body Protection

Set up good ventilation and exhaust system in the work area.
Glycerol (mist)
Not established
10mg/m3
total dust:15mg/m3TWA
3Wear a dust mask.
Chemical safety gloves.
Chemical safety goggles.
Long sleeves to prevent contact with skin.

9 PHYSICAL AND CHEMICAL PROPERTIES
Physical State, Form, Colour
OdourpH
Flash Point

liquid over -20°C, ColourlessNone
7.0-9.0
No flammability for aqueous solution, but glycerol with the flash point of160℃ may remain after volatilization of water.

Boiling Point
Melting Point

Not available
Not available
Not available
1.0-1.2
Soluble in water

Decomposition TemperatureSpecific gravity
Solubility

10 STABILITY AND REACTIVITY
Chemical stability and hazardous reactions Stable at -20℃ or below. Decomposes gradually at normal temperature,
but not dangerous reaction.

Conditions to Avoid
Incompatible materials
Hazardous decomposition products

Strong heat, Direct sunlight
Strong oxidizers, Strong reducers
Not available

11 TOXICOLOGICAL INFORMATION
Acute Toxicity
Skin irritation/corrosion
Eye damage/irritation
Specific target organ toxicity-single exposure
Acute Toxicity
Local Effects

Not available
May cause skin irritation.
May cause eye irritation.
May cause respiratory irritation.
Not available
May cause eye and skin irritation. May cause respiratory and digestive

12 ECOLOGICAL INFORMATION
Ecotoxicity

GlycerolRainboutrout:LC50(96hr) 54g/L
Gold fish:LC50(24hr)＞5g/L

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Uracil-DNA Glycosylase, Heat-labile
First issue : Oct. 2, 2018
Revised : Apr. 1, 2021
SDS No.1600F

Safety Data SheetGold fish:LC50(24hr)＞5g/L
Daphnia magna:EC50(24hr)＞10g/L
Red algae:EC50(28hr) 4.6g/L

Persistence and degradability
Bioaccumulative potential
Mobility in soil
Other adverse effects

13 DISPOSAL CONSIDERATIONS
Waste from Residues
Contaminated container andContaminated packaging

Rapidly biodegradable.
Not available

Soluble in water and diffusible into water environment.
Not available

Dispose of in accordance with all applicable local and national laws andregulations.
Dispose of in accordance with all applicable local and national laws andregulations.

14 TRANSPORT INFORMATIONInternational Regulations
UN Classification Number
Specific Precautions

15 REGULATORY INFORMATION
16 OTHER INFORMATION
NoticeNot classified
Follow all of the laws and regulations in your respective country.
To prevent packages from breaking, handle with care.

Follow all of the laws and regulations in your country.

The information in this SDS, to the best of our knowledge, is accurate
and correct. However, TOYOBO makes no warranty and assumes noliability whatsoever in connection with any use of this information.
The SDS is subject to revision as new information becomes available.