1/4TMGenNext

NGS Library Quantification Kit
First issue : Mar. 31, 2016

SDS No.1204F

Safety Data Sheet

1 PRODUCT AND COMPANY IDENTIFICATION
Product Name
Product Code
SUPPLIERName
Address
Department
Emergency Telephone No.
Fax No.
Recommended use andrestrictions on use

TMGenNext
NLQ-101

NGS Library Quantification Kit

TOYOBO Co., Ltd.
2-2-8 Dojima Hama Kita-ku Osaka, 530-8230 Japan
Biotech supportｎ Department+81-6-6348-3786+81-6-6348-3833
Real-Time PCR kit(Reagent for research)

2 HAZARDS IDENTIFICATION
Most Important Hazards
GHS Classification

Few adverse human health effects are anticipated.

Hazard class and category
Physical Hazards

Classification not possible

Health Hazards
50× ROX
ReferenceDyeStandard DNA
1~650 x Dilution
Buffer

5 x Primer Mix

Classification
not possible

Classification
not possible

Classification
not possible

Classification
not possible

Classification
not possible

Classification
not possible

Classification
not possible

Classification
not possible

Classification
not possible

Classification
not possible

Classification
not possible

Classification
not possible

KOD SYBR®
qPCR Mix
Category 5
Acute toxicity - oral
Category 3
Skin corrosion/Irritation

Serious eye damage/Eyeirritation

Classificationnot possible

Environmental Hazards

Classification not possible

Label elements<KOD SYBR® qPCR Mix>
Pictograms or symbols―Signal wordWarning
Hazard statements

May be harmful if swallowed.
Causes mild skin irritation.

Precautionary statement(s)Prevention
Call a POISON CENTER or doctor / physician if you feel unwell.
Response

If skin irritation occurs: Get medical advice / attention.

2/4
TM

GenNext

NGS Library Quantification Kit
First issue : Mar. 31, 2016

SDS No.1204F

Safety Data Sheet

3 COMPOSITION / INFORMATION ON INGREDIENTS
Chemical Product(Substance/Preparation)
Chemical Nature

MixtureAqueous solution of enzyme, substrate, etc.
Parts Name
Main components
CAS No. (EC NO.)
77-86-1
KOD SYBR® qPCR Mix Tris(Hydroxymethyl)aminomethane
Nondisclosure
Additive1
Nondisclosure
Additive2(EC 2.7.7.7)
DNA polymerase－
monoclonal antibody
163795-75-3
SYBR® Green I－
50× ROX Reference Dye ROX Reference Dye
Deoxyribonucleic acid－
Standard DNA 1
Deoxyribonucleic acid－
Standard DNA 2
Deoxyribonucleic acid－
Standard DNA 3
Deoxyribonucleic acid－
Standard DNA 4
Deoxyribonucleic acid－
Standard DNA 5
Deoxyribonucleic acid－
Standard DNA 677-86-1
Tris(Hydroxymethyl)aminomethane
50 x Dilution Buffer
Deoxyribonucleic acid－
5 x Primer Mix

Components Contributing to the Hazard
Common Chemical Name
Additive1(or Generic Name)
Synonyms
Nondisclosure
Contained
KOD SYBR® qPCR
Parts:Percentage
Mix ：<3%Chemical formula
CAS No.
Concentration

Nondisclosure
Nondisclosure<3%

Additive2
Nondisclosur
KOD SYBR®
qPCR Mix ：<15%
Nondisclosur
Nondisclosur<15%

4 FIRST-AID MEASURES
Inhalation
Skin Contact
Eye Contact

Ingestion

Remove person to fresh air. Call a doctor if you feel unwell.
Wash with clean water, immediately.
Rinse cautiously with water for several minutes. Remove contact lenses,
if present and easy to do. Continue rinsing.
If eye irritation persists: Get medical advice / attention.
If swallowed: Rinse mouth. Do NOT induce vomiting.
If indisposition continues, seek medical attention.

5 FIRE-FIGHTING MEASURESExtinguishing Media
Protection of fire-fighters

Water, Carbon Dioxide, Foam, Dry Chemical Powder
Fire-fighting should be done from the windward side of fire area. Fire-fighters shouldwear proper protective equipment in case of large scale fire.

6 ACCIDENTAL RELEASE MEASURES
Personal Precautions
Wear protective gear to avoid eye/skin contact and inhalation.
Environmental Precautions Avoid disposition to the environment.
Methods for Cleaning up
Use cloth, paper or anything similar to soak up the solution leaking out of the container.
Take up under vacuum

7 HANDLING AND STORAGE
HANDLING
Technical Measures
Precautions
Safe Handling Advice
STORAGETechnical Measures
Storage Conditions
Incompatible Products
Packaging Materials

Wear protective equipments and avoid contact with eyes and skin. Handle withventilation and local exhaust system.

Avoid substance contact .After handling, wash hands with clean water.
Always keeping things tidy and in order, and keep laboratory Clean.
Store in the original
Store at about -20°C
Oxidizers
Store in the original

3/4
TMGenNext

NGS Library Quantification Kit
First issue : Mar. 31, 2016

SDS No.1204F

Safety Data Sheet
8 EXPOSURE CONTROLS/ PERSONAL PROTECTION
ENGINEERING MEASURES Set up good ventilation and exhaust system in the work area.
Control Parameter
Limit Values

JSOH OELACGIH TLVOSHA PEL

Additive1

Additive2

Not establishedNot establishedNot establishedNot establishedNot establishedNot establishedPERSONAL PROTECTIVE EQUIPMENT
Respiratory Protection
Wear a dust mask.
Hand Protection
Chemical safety gloves.
Eye Protection
Chemical safety
Skin and Body Protection Long sleeves to prevent contact with skin.

9 PHYSICAL AND CHEMICAL PROPERTIES
Physical State

KOD SYBR® qPCR Mix, 50× ROX Reference Dye, Standard DNA1, Standard DNA2,Standard DNA3, Standard DNA4, Standard DNA5, Standard DNA6, 50 x Dilution Buffer
and 5 x Primer Mix are liquid at ambient temperatures and freeze at -20°C.

ColourOdour
pH
Flash Point

None
None
7.0-9.0
No flammability due to aqueous solution, but additive2 whose flash point 131℃ may staybehind after volatilization KOD SYBR® qPCR Mix.
No Data
No Data
No Data
1.0-1.2
Soluble in water

Boiling Point
Melting Point
Decomposition TemperatureSpecific Gravity
Solubility

10 STABILITY AND REACTIVITY
Stability
Stable at -20°C
Possible Hazardous Reactions None
Conditions to Avoid
Strong heat and Direct
Material to Avoid
strong oxidizers and strong reducers
Hazardous Decomposition
Noinformation
Productavailable

11 TOXICOLOGICAL INFORMATION<KOD SYBR® qPCR Mix>
Acute Toxicity
No data available
Local Effects
May cause eye and skin irritation. May cause respiratory tract irritation.
Toxicological information on the component of this product

Additive1
Acute toxicity (LD50)
Skin corrosion/Irritation
Serious eye damage/Eyeirritation

Additive2

Oral-rat: 50mg/kg*
Oral-mouse:sification not possible
Category 2
Category 3

sification not possible*Acute toxicity (LD50) of Additive is estimated from similar agent.

12 ECOLOGICAL INFORMATION
No data available
Ecotoxicity
Persistence/Degradability

Enzyme, protein and nucleotide are biodegradable.

Mobility

Soluble in water and diffusible into water environment.

4/4
TMGenNext

NGS Library Quantification Kit
First issue : Mar. 31, 2016

SDS No.1204F

Safety Data Sheet
13 DISPOSAL CONSIDERATIONS
Waste from Residues

Dispose of in accordance with all applicable local and national laws and regulations.

Contaminated Packaging

Dispose of in accordance with all applicable local and national laws and regulations.

14 TRANSPORT INFORMATIONInternational Regulations
UN Classification Number
Specific Precautions

Not classified
Follow all of the laws and regulations in your respective country.
To prevent packages from breaking, handle with care. Store at about -20°C when it is

15 REGULATORY INFORMATION
Follow all of the laws and regulations in your country.

16 OTHER INFORMATION
NoticeThis product is sold for research purposes only . It is not intended for food, drug,
household, agricultural or cosmetic use. Its use must be supervised by a technicallyqualified individual experienced in handling potentially hazardous chemicals. The
information in this SDS, to the best of our knowledge, is accurate and correct. However,
TOYOBO makes no warranty and assumes no liability whatsoever in connection with any
use of this information. The information shall not be taken as being all inclusive and is to
be used only a guide. All materials and mixtures may be present unknown hazards andshould be used with caution. The SDS is subject to revision as new information becomes
available.