Humane Sciencein the 21st Century
Scientific Programme – draft April 2013
1. New technologies
a. Virtual tissue models
b. HTSc. BIG data
d. Novel computational biology tools
e. Tissue on a chip
f. 3D models
g. Bioreactors
h. Bioimaging
i. Monitoring, telemetryj. Advanced human-based diagnostic techniques
k. New readout technologies
2. Predictive Toxicology and safety assessment
a. Pathway approaches in toxicology (AOP)b. Systems biology (-omics)c. Update on Tox21
d. Update on SEURAT-1
e. Exposure
f. Topical toxicity
g. Repeated dose toxicityh. Skin sensitization
i. Endocrine disruption
j. Genotoxicity / Carcinogenicity
k. Reproductive and developmental toxicology
l. Inhalation toxicity
m. Ecotoxicology
n. Computational modeling and chem-informatics(e.g. QSAR, mechanistic chemistry)o. Risk assessment (e.g. chemicals, drugs, biocides, food,cosmetics, medical devices, nano materials, mixtures,biologicals etc.)
p. Application in decision making and testing strategies

3. 3Rs in academia and educationa. Information requirements on researchers(e.g. Directive 63/2010)b. Training programs and anticipated needsc. 3Rs in academic educationd. Funding programs (e.g. Horizon 2020)
e. Funding agencies
f. Innovative teaching and training tools
g. Beneﬁts of 3Rs – case studies
4. Communication, dissemination and data sharinga. Scientiﬁc reporting standards
b. Retrospective analysis / non-technical summaries (63/2010)
c. Information systems and databasesd. Intellectual property and data ownership
5. Efficacy and safety testing of drugs and biologicals
a. Pathway-based assays
b. Alternative disease models
c. Screening strategies
d. Potency of human and veterinarian vaccines
6. Human relevance (in vivo, in vitro)a. Stem cells (screening)b. Disease models
c. Human biomarkers
d. IVIVE
e. ADMEf. Challenges in translational biology
g. Pros and cons of animal models (plenary)

7. Ethics
a. Use of materials of human originb. Testing in human volunteers
c. Distress evaluationd. Beneﬁt evaluatione. Transgenics
8. Refinement and welfare
a. NHPsb. Primatesc. Welfare approachesd. Humane principles in experimental techniquese. Avoidance of severe suffering
9. Global cooperation, regulatory acceptance,
standardization
a. Regulatory acceptance of alternatives
b. Progressing validationc. Update from validation centersd. Good cell culture practicee. Challenges to 3Rs
f. Barriers for international harmonization and mutualacceptanceg. Legal constrains and uncertainties
h. Trade barriers
i. Animal welfare implementation across the world
j. Update from international societies

9th World Congress
on Alternatives and Animal
Use in the Life Sciences
24–28 August 2014
Prague, Czech Republic

The abstracts will be published in an international
scientific journal focused on 3Rs with impact factor.

www.wc9prague.org

Congress Co-Chairs
DagmarJírová

HorstSpielmann

Local Organizing Committee
Dagmar Jírová
National Institute of Public Health,Czech Republic
Miroslav ČervinkaFaculty of Medicine, Charles University,
Czech Republic
Barbora Večlová
Freedom for Animals, Czech Republic
Lukáš JebavýSociety for Science on Laboratory Animals,
FELASA, Czech Republic
Rostislav Čihák
Center of Ecology, Toxicology and Analytics,
VUOS, Czech Republic
Helena KanďárováMatTek In Vitro Life Science Laboratories,
Slovak Republic
Kristina Kejlová
National Institute of Public Health,
Czech Republic

ACT Members
Herman KoëterActing Chairman, Secretary, Belgium
Thomas Hartung
Treasurer, United States of America
Michael Balls
United Kingdom
Coenraad Hendriksen
Netherlands
Andrew Rowan
United States of America
Horst Spielmann
GermanyRegistration
To register, please use exclusively our internet registration format www.wc9prague.org. The form will be opened in October 2013.

Committees
Scientific Programme Committee
Nathalie Alépée
L‘Oréal, France
Kevin Crofton
US EPA, United States of America
Miroslav ČervinkaCharles University, Czech Republic
Mardas Daneshian
CAAT Europe, Germany
Chantra Eskes
ESTIV, Switzerland
Tuula Heinonen
SSCT & ECOPA, Finland
Helena KanďárováSETOX & MatTek, Slovak Republic
Hajime Kojima
JaCVAM, Japan
Roman Kolar
Eurogroup for Animals, Germany
Robert Landsiedel
BASF, Germany
Clive RoperCharles River Laboratories, United Kingdom
Harald Schlatter
P&G, Germany
Gilbert Schönfelder ZEBET, Germany
Carl Westmoreland
Unilever, United Kingdom
Maurice Whelan
EURL ECVAM, JRC, Italy

Congress Secretariat
GUARANT International spol. s r.o.
Na Pankráci 17
140 21 Prague 4, Czech RepublicTel.: +420 284 001 444
Fax: +420 284 001 448
E-mail: wc9.secretariat@guarant.cz
Website: www.wc9prague.org

Social ProgrammeSunday, 24 August 2014Get-Together Party at Hotel Hilton Prague
included in the registration fee

General Information
Congress Venue
Hotel Hilton PraguePobřežní 311/1
186 00, Prague 8 – Karlín
Czech RepublicMonday, 25 August 2014
Welcome Reception at Public Spa
included in the registration fee

Registration fees
Payment

Earlyregistration
by June 1,2014

Lateregistration
on & afterJune 1, 2014

On-siteregistration

Full Participation

€ 530

€ 580

€ 635

Full Participation,
Students / young
scientistic*

€ 380

€ 430

€ 475

AccompanyingPerson

€ 300

€ 350

€ 390

*Students/young scientists under 30 are eligible when presenting
an official confirmation of enrolment at a scientific institution.

Important Dates
Registration Opens
Abstract Submission Opens
Abstract Submission Deadline
Early Registration Deadline
9th World Congress on Alternatives& Animal Use in the Life Sciences

October 2013
October 2013
April 2014
May 2014
24–28 August 2014

The Full Participation includes:
Admission to all scientiﬁc events and exhibition, the Opening
and Closing Cremony, the Get-Together Party on Sunday,
the Welcome Cocktail on Monday, the Gala Dinneron Wednesday, coffee breaks and light lunches.

Accommodation
Prague offers large capacities of all types of accommodation.
Delegates will have the opportunity to choose from luxury
ﬁve-star hotels to three-star hotels. Most of the proposed
hotels are easily accessible – on foot or in 5–20 minutes by
public transport.

The registration fee for Accompanying Persons includes:
The Opening and Closing Ceremony, the Get-Together Partyon Sunday, the Welcome Cocktail on Monday, the Gala Dinneron Wednesday.

• 900 hotel rooms within a walking distance• Around 80,000 hotel beds
• Accommodation in various categories(luxury 5* hotels, economy 3–4* hotels, student hostels)

The registration fees do not include accommodationand travel costs.

The hotel reservation will beavailable from autumn 2013.

Wednesday, 27 August 2014
Gala Dinner at Municipal House

For more information on the scientiﬁc programme, abstract
submission, registration, hotel reservation and social programme
please visit our website: www.wc9prague.org.