1/5rTaq DNA Polymerase
Oct. 26, 2017

SDS No.1068F

Safety Data Sheet

1 CHEMICAL PRODUCT AND COMPANY IDENTIFICATION
Identification of the productProduct Code
SUPPLIERNameAddress
Department
Telephone No.
Fax No.
Recommended use andrestrictions on use

rTaq DNA Polymerase
TAP-201, 211, 229E, 259E, 2M, 2B, 2S
TOYOBO Co., Ltd.
2-2-8 Dojima Hama Kita-ku Osaka, 530-8230 Japan
Biotech support Department+81-6-6348-3786+81-6-6348-3833
PCR for DNA amplification(Reagent for research)

2 HAZARDS IDENTIFICATION
Parts Name
Most Important Hazards
Specific Hazards
GHS Classification
Hazard class and category
Physical Hazards
Health Hazards
Environmental Hazards
Label elements
Pictogram or symbol
Signal word
Hazard statement
Precautionary statement
ResponseParts Name
Most Important Hazards
Specific Hazards
GHS ClassificationrTaq DNA Polymerase
rTaq DNA Polymerase contain glycerol and may cause eye and skinirritation. Few adverse human health effects are anticipated.
Not available

Flammable liquids
Skin corrosion /Irritation
Serious eye damage /Eye irritation

Not classified
Category 3
Category 2B
Classification not possibleWarning
Causes mild skin irritation
Causes eye irritation
Wash hands thoroughly after handlingIf skin irritation occurs: Get medical advice/attention.
IF IN EYES: Rinse cautiously with water for several minutes. Remove
contact lenses if present and easy to do. Continue rinsing. If eyeirritation persists: Get medical advice/attention.
10x PCR Buffer and 2mM dNTPs
Few adverse human health effects are anticipated.
Not available
Classification not possible

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rTaq DNA Polymerase
Oct. 26, 2017

SDS No.1068F

Safety Data Sheet

3 COMPOSITION / INFORMATION ON INGREDIENTS
Chemical Product(Substance/Mixture)
Chemical Nature
Parts NamerTaq DNA Polymerase

MixtureCAS No.
Main components
Taq DNA polymerase(EC 2.7.7.7)
Poly(oxyethylene)nonylphenyl ether 9016-45-9

10x PCR Buffer

Polyoxyethylene Sorbitan
9005-64-5
Monolaurate
56-81-5GlycerolTris(Hydroxymethyl)aminomethane 77-86-1

2mM dNTPs

Deoxyadenosine triphosphate
Deoxycytidine triphosphate

102783-51-7

Deoxyguanosine triphosphate

93919-41-6

Deoxythymidine triphosphate

18423-43-3

Components Contributing to the Hazard
Common Chemical Name
Glycerol(or Generic Name)
Synonyms
Glycerin
Contained
rTaq DNA Polymerase：50%
Chemical formula
CH2OHCHOHCH2OH
CAS No.

1927-31-7

Poly(oxyethylene)nonylphenylether
Nonidet P-40
rTaq DNA Polymerase：0.5%
HO(C2H4O)n-C6H4-C9H19

56-81-59016-45-9

Components Contributing to the Hazard
Common Chemical Name Polyoxyethylene Sorbitan Monolaurate(or Generic Name)
Synonyms
Tween20
Contained
rTaq DNA Polymerase：0.5%
Chemical formula
C11H23COOC6H8[O(CH2CH2O)nH]
CAS No.

9005-64-5

4 FIRST-AID MEASURES
Inhalation

Skin Contact
Eye Contact
Ingestion

In case of irritation by inhaling this product, move affected person tofresh air and await recovery. If irritation persists, seek immediate
medical attention.
Wash with plenty of clean water, immediately.
Rinse cautiously with water several minutes. Remove contact lenses if
present and easy to do. Continue rinsing. If eye irritation persists, seek
medical attention.
Induce vomiting.
If indisposition continues, seek medical attention.

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rTaq DNA Polymerase
Oct. 26, 2017

SDS No.1068F

Safety Data Sheet

5 FIRE-FIGHTING MEASURESExtinguishing Media
Protection of fire-fighters

Water, Carbon Dioxide, Foam, Dry Chemical Powder
Fire-fighting should be done from the windward side of fire area. Firefighters should wear proper protective equipment in case of large scalefire.

6 ACCIDENTAL RELEASE MEASURES
Personal Precautions
Environmental Precautions
Methods for Cleaning up

Wear protective gear to avoid eye/skin contact and inhalation.
Avoid disposition to the environment.
Use cloth, paper or anything similar to soak up the solution leaking outof the container. Take up under vacuum using dust collecting filter.

7 HANDLING AND STORAGE
HANDLINGTechnical Measures
Precautions
Safe Handling Advice
STORAGETechnical Measures
Storage Conditions
Packaging Materials

Wear protective equipments and avoid contact with eyes and skin.
Handle with ventilation and local exhaust system.
Avoid substance contact. After handling, wash with clean water.
Good laboratory technique should be used when handling this product.

Store in the laboratory bottle
Store at about -20°C
Store in the original package

8 EXPOSURE CONTROLS/ PERSONAL PROTECTION
ENGINEERING MEASURES Set up good ventilation and exhaust system in the work area.
Control ParameterPoly(oxyethylene)
Limit ValuesGlycerol
Nonylphenylether
JSOH OEL
Not establishedNot established
ACGIH TLV
10mg/m3
Not established
OSHA PEL
total dust:15mg/m3TWA

respirable fr.: 5mg/m3TWA

Not establishedPERSONAL PROTECTIVE EQUIPMENT
Respiratory Protection
Wear a dust mask.
Hand Protection
Chemical safety gloves.
Eye Protection
Chemical safety goggles.
Skin and Body Protection Long sleeves to prevent contact with skin.

9 PHYSICAL AND CHEMICAL PROPERTIES
Physical State

Boiling Point
Melting Point
Decomposition TemperatureDensity

Liquid. 10x PCR Buffer and 2mM
dNTPs freeze at -20℃None
None
7.0-8.0
No flammability due to aqueous solution, but glycerol whose flash point
160℃ may stay behind after volatilization rTaq DNA Polymerase.
Not available
Not available
Not available
1.0-1.2(g/cm3)

Solubility

Soluble in waterColour
Odour
pHFlash Point4/5

rTaq DNA Polymerase
Oct. 26, 2017

SDS No.1068F

Safety Data Sheet

10 STABILITY AND REACTIVITY
Stability
Possible Hazardous Reactions
Conditions to Avoid
Material to Avoid
Hazardous Decomposition
ProductStable at below -20℃
None
Strong heat
Direct sunlight, strong oxidizers and strong reducers
Not available

11 TOXICOLOGICAL INFORMATION
Not available
May cause eye and skin irritation. May cause respiratory and digestive
tract irritation.
Toxicological information on the component of this product
GlycerolPoly(oxyethylene)nonylphenylether
Acute Toxicity
Local Effects

Acute toxicity (LD50)
Skin corrosion/Irritation
Serious eye damage/Eyeirritation

Oral-mouse: 4090mg/kg
Oral-rat: 12.6g/kg
rabbit:500mg/24hr:Mild
rabbit:126mg/24hr:Mild

Oral-mouse: 3500mg/kg
Oral-rat: 4190mg/kg

12 ECOLOGICAL INFORMATION
Ecotoxicity

Mobility
Persistence/Degradability
BioaccumulationMobility in Soil
Hazard to the ozone layer

Rainboutrout:LC50(96hr) 54g/L
Gold fish:LC50(24hr)＞5g/L
Daphnia magna:EC50(24hr)＞10g/L
Red algae:EC50(28hr) 4.6g/L
Soluble in water and diffusible into water environment.
Rapidly degradable BOD
Not bioaccumulative (LogPow=-2.3)
Not available
Not available

13 DISPOSAL CONSIDERATIONS
Waste from Residues
Contaminated Packaging

Dispose of in accordance with all applicable local and national laws andregulations.
Dispose of in accordance with all applicable local and national laws andregulations.

14 TRANSPORT INFORMATIONInternational Regulations
UN Classification Number
Specific Precautions

Not classified
Follow all of the laws and regulations in your respective country.
To prevent packages from breaking, handle with care.

15 REGULATORY INFORMATION
Follow all of the laws and regulations in your country.

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rTaq DNA Polymerase
Oct. 26, 2017

SDS No.1068F

16 OTHER INFORMATION
NoticeSafety Data Sheet

The information in this SDS, to the best of our knowledge, is accurate
and correct. However, TOYOBO makes no warranty and assumes noliability whatsoever in connection with any use of this information.
The SDS is subject to revision as new information becomes available.