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KOD OneTM

PCR Master Mix (-Blue-)First issue : Jul. 3, 2018
Revised : May. 24, 2024
SDS No. 1462F

Safety Data Sheet
1 PRODUCT AND COMPANY IDENTIFICATION
Product Name
Product Code
SUPPLIERName
Address
Department
Emergency Telephone No.
Fax No.
Recommended use andrestrictions on use

KOD One TM PCR Master Mix (-Blue-)
KMM-101、KMM-101S、KMM-101L、KMM-101NV、KMM-101NVS、KMM-121、KMM-151、KMM-201、 KMM-201S、KMM-201NV、KMM-201NVS、KMM-221、KMM-251
TOYOBO Co., Ltd.
Osaka Umeda Twin Towers South, 1-13-1 Umeda Kita-ku, Osaka 530-0001, JapanBiotechnology Overseas Sales and Marketing Department+81-6-6348-3846+81-6-6348-3833
PCR kit for DNA amplification

2 HAZARDS IDENTIFICATION
Most Important Hazards
GHS Classification
Hazard class and category
Physical Hazards
Health Hazards
Acute toxicity - oral
Skin corrosion/Irritation
Serious eye damage/Eyeirritation
Environmental Hazards

Few adverse human health effects are anticipated.

Classification not possible
Category 5
Category 3
Classification not possible
Classification not possible

Label elements
Pictograms or symbols
Signal word―WarningMay be harmful if swallowed.
Hazard statements
Causes mild skin irritation.
Precautionary statement(s)Prevention―Response
Call a POISON CENTER or doctor / physician if you feel unwell.
If skin irritation occurs: Get medical advice / attention.

3 COMPOSITION / INFORMATION ON INGREDIENTS
Chemical Product(Substance/Preparation)
Chemical Nature

MixtureAqueous solution of enzyme, substrate, etc.
Main components
CAS No. (EC NO.)
Tris(Hydroxymethyl)aminomethane 77-86-1

Magnesium sulfate
Deoxyadenosine triphosphate
Deoxycytidine triphosphate
Deoxyguanosine triphosphate
Deoxythymidine triphosphate
AdditiveDNA polymerase
monoclonal antibody
GlycerolPoly(oxyethylene)
Nonylphenylether
Components Contributing to the Hazard
Common Chemical Name
Glycerol(or Generic Name)
Synonyms
Glycerin
Contained<5%Parts:Percentage
Chemical formula
CH2OHCHOHCH2OH
CAS No.

56-81-57487-88-9
1927-31-7
102783-51-7
93919-41-6
18423-43-3
Nondisclosure(EC 2.7.7.7)
56-81-59016-45-9

Poly(oxyethylene)
Nonylphenylether
Nonidet P-40

Additive
Nondisclosure<0.01%<3%HO(C2H4O)n-C6H4-C9H19
9016-45-9

Nondisclosure
Nondisclosure

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KOD OneTMPCR Master Mix (-Blue-)First issue : Jul. 3, 2018
Revised : May. 24, 2024
SDS No. 1462F

Safety Data Sheet
4 FIRST-AID MEASURES
Inhalation

Remove person to fresh air. Call a doctor if you feel unwell.

Skin Contact
Eye Contact

Wash with clean water, immediately.
Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do.
Continue rinsing.
If swallowed: Rinse mouth. Do NOT induce vomiting.
If indisposition continues, seek medical attention.

Ingestion

5 FIRE-FIGHTING MEASURESExtinguishing Media
Water, Carbon Dioxide, Foam, Dry Chemical Powder
Specific extinguishing methods
Fire-fighting should be done from the windward side of fire area.
Protection of fire-fighters
Fire-fighters should wear proper protective equipment in case of large scale fire.

6 ACCIDENTAL RELEASE MEASURES
Personal Precautions
Environmental Precautions
Methods for Cleaning up

Wear protective gear to avoid eye/skin contact and inhalation.
Avoid disposition to the environment.
Use cloth, paper or anything similar to soak up the solution leaking out of the container. Take up undervacuum using dust collecting filter.

7 HANDLING AND STORAGE
HANDLING
Technical Measures
Safe Handling Advice
Hygiene measures
STORAGETechnical Measures
Storage Conditions
Incompatible Products
Packaging Materials

Wear protective equipments and avoid contact with eyes and skin. Handle with ventilation and local
exhaust system.
Always keeping things tidy and in order, and keep laboratory Clean..
After handling, wash hands with clean water.
Store in the laboratory bottle
Store at about -20°C
Oxidizers
Store in the original package.

8 EXPOSURE CONTROLS/ PERSONAL PROTECTION
ENGINEERING
Control Parameter
Limit Values
JSOH OELACGIH TLVOSHA PEL

Set up good ventilation and exhaust system in the work area.
GlycerolPoly(oxyethylene)
Nonylphenylether

Additive

Not establishedNot establishedNot establishedNot establishedNot establishedNot establishedNot established
10mg/m3
total dust:15mg/m3TWA
respirable fr.: 5mg/m3TWAPERSONAL PROTECTIVE EQUIPMENT
Respiratory Protection
Wear a dust mask.
Hand Protection
Chemical safety gloves.
Eye Protection
Chemical safety goggles.
Skin and Body Protection Long sleeves to prevent contact with skin.

9 PHYSICAL AND CHEMICAL PROPERTIES
Physical State
ColourOdour
pHFlash Pointliquid
KOD OneTM PCR Master Mix: None
KOD OneTM PCR Master Mix -Blue-: BlueNone
7.0-9.0
No flammability due to aqueous solution, but glycerol whose flash point 160°C may stay behind aftervolatilization.
Boiling PointClassification not possible
Melting PointClassification not possible
Decomposition Temperature Classification not possible
Specific Gravity
1.0-1.2
Solubility
Soluble in water

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KOD OneTM

PCR Master Mix (-Blue-)First issue : Jul. 3, 2018
Revised : May. 24, 2024
SDS No. 1462F

Safety Data Sheet
10 STABILITY AND REACTIVITY
Stability
Stable at -20°C
Possible Hazardous ReactionsNone
Conditions to Avoid
Strong heat and Direct sunlightMaterial to Avoid
strong oxidizers and strong reducers
Hazardous Decomposition
Classification not possible
Product11 TOXICOLOGICAL INFORMATION
Acute Toxicity
Classification not possible
Skin corrosion/ irritation
May cause eye and skin irritation.
Serious eye damage/ eye
May cause respiratory tract irritation.
irritation
Toxicological information on the component of this product
GlycerolAcute toxicity (LD50)

Oral-mouse: 4090mg/kg
Oral-rat: 12.6g/kg
Category 3

Skin corrosion/Irritation
Serious eye damage/Eye
Category 2Birritation*Acute toxicity (LD50) of Additive is estimated from similar agent.

Poly(oxyethylene)
Nonylphenylether
Oral-mouse: 3500mg/kg
Oral-rat: 4190mg/kg
Category 3

Oral-rat: 50mg/kg*

Category 2ACategory 3

Additive

Category 2

12 ECOLOGICAL INFORMATION
Ecotoxicity
Persistence/Degradability

Not available
Poly(oxyethylene) nonylphenylether isn't biodegradable. Enzyme, protein and glycerol are biodegradable.

Bioaccumulation
Mobility

Not available
Soluble in water and diffusible into

13 DISPOSAL CONSIDERATIONS
Waste from Residues
Contaminated Packaging

Dispose of in accordance with all applicable local and national laws and regulations.
Dispose of in accordance with all applicable local and national laws and regulations.

14 TRANSPORT INFORMATIONInternational Regulations
UN Classification Number Not classified
Follow all of the laws and regulations in your respective country.
Specific Precautions
To prevent packages from breaking, handle with care. Store at about -20°C when it is transported.

15 REGULATORY INFORMATION
Follow all of the laws and regulations in your country.

16 OTHER INFORMATION
NoticeIts use must be supervised by a technically qualified individual experienced in handling potentiallyhazardous chemicals. The information in this SDS, to the best of our knowledge, is accurate and correct.
However, TOYOBO makes no warranty and assumes no liability whatsoever in connection with any use ofthis information. The information shall not be taken as being all inclusive and is to be used only a guide.
All materials and mixtures may be present unknown hazards and should be used with caution. The SDS is
subject to revision as new information becomes available.