PROGRAMPROGRAM
Day1: October 27 (Wed.)
09:30-09:40

Instructions
Manabu Ozawa[Associate Professor, The Institute of Medical Science, The University of Tokyo (IMSUT)]

09:40-09:55

Opening remarks
Yuji Yamanashi[Dean/Professor, IMSUT]

09:55-10:35

Self-introduction of each institution
Yuji Yamanashi[Dean/Professor, IMSUT]

Mary Collins[Provost, Okinawa Institute of Science and Technology Graduate University (OIST)]
Jongkyeong Chung[Director/Professor, Institute of Molecular Biology and Genetics, School of Biological
Sciences, Seoul National University (IMBG)]
Haitao Yang
[Executive Director, Shanghai Institute for Advanced Immunochemical Studies (SIAIS),
ShanghaiTech University]
Yoshio Koyanagi[Director/Professor, Institute for Frontier Life and Medical Sciences, Kyoto University(INFRONT)]
Ming-Shyue Lee[Chair/Professor, Institute of Biochemistry and Molecular Biology, National Taiwan
University (IBMB)]JianFeng Chen
[Assistant Director/Professor, Shanghai Institute of Biochemistry and Cell Biology,
Chinese Academy of Sciences (SIBCB)]

11:45-12:00
O-5

Central control of body temperature
Wei Shen [Associate Professor, School of Life Science and Technology (SLST),
ShanghaiTech University]

12:00-13:15

Lunch

Chair: Jing-Jer Lin [Professor, IBMB]

10:45-11:00
O-1

Understanding the roles of microenvironment in regulating skin fibrosis
Yongsung Hwang [Associate Professor, SIMS]

11:00-11:15
O-2

Selective autophagy networks in senescence
Chanhee Kang [Assistant Professor, IMBG]

11:15-11:30
O-3

Stem cell-centric mechanisms of organ aging: Lesson from the skinEmi K. Nishimura [Professor, IMSUT]

The 27th East Asia Joint Symposium

Chair: Tomoji Mashimo [Professor, IMSUT]

13:15-13:30
O-6

Serine protease inhibitor HAI-2 as a tumor suppressor against prostate cancer progression
Ming-Shyue Lee [Chair/Professor, IBMB]

13:30-13:45
O-7Regeneration of cytotoxic T lymphocytes from iPS cells: Development of “off-the-shelf
T cells” for cell therapy targeting cancer and viral infection
Hiroshi Kawamoto [Professor, INFRONT]

13:45-14:00
O-8

CRISPR screening to identify the key modulators for effective immunotherapy
Guangchuan Wang [Professor, SIBCB]

14:00-14:15
O-9

Development and applications of CRISPR-KO screening
Kosuke Yusa [Professor, INFRONT]

14:15-14:25

BreakSession 3 : Genome science

Chair: Kosuke Yusa [Professor, INFRONT]

14:25-14:40
O-10

Application of genome editing technology CRISPR-Cas3 in gene therapy
Tomoji Mashimo [Professor, IMSUT]

14:40-14:55
O-11

Another tale of M13 bacteriophages
Jia Liu [Assistant Professor, SIAIS, ShanghaiTech University]

14:55-15:10
O-12

Big data technologies for genome science
Tetsuo Shibuya [Professor, IMSUT]

15:10-15:25
O-13

Structure-based protein function prediction and mechanism study
Suwen Zhao [Assistant Professor, iHuman Institute/SLST, ShanghaiTech University]

15:25-15:40

Break

15:40-17:00

Young Scientist Session/Student Session at Zoom breakout room
Young Scientist Session: Breakout room 1
Student Session: Breakout room 2

17:00-17:10

BreakBreakSession 1 : Aging and degenerative disorders

4Reduction in endoplasmic reticulum stress activates beige adipocytes differentiation andalleviates high fat diet-induced metabolic phenotype
Jaeseok Han [Associate Professor, SIMS]

Session 2 : Cancer

Jeong KyoYoon[President/Professor, Soonchunhyang Institute of Medi-bio Science, Soonchunhyang
University (SIMS)]

10:35-10:45

11:30-11:45
O-4

Session 4 : Development and stem cell

Chair: Mototsugu Eiraku [Professor, INFRONT]

17:10-17:25
O-14

Genetic approaches for identifying novel regulators during respiratory development andhomeostasis
Hyun-Taek Kim [Assistant Professor, SIMS]

17:25-17:40
O-15

Paternal chromatin remodeling in mammalian reproduction and infertility
Lan-Tao Gou [Principal Investigator, SIBCB]The 27th East Asia Joint Symposium

5PROGRAM

17:40-17:55
O-16

Gene expression control of embryonic reprogramming in Drosophila
Mihye Lee [Associate Professor, SIMS]

17:55-18:10
O-17

Essential role of Dynein Road Block 1 in the survival of adult sensory neurons
Marco Terenzio [Assistant Professor, OIST]

18:10-18:25
O-18

Modeling of liver tissue structures ex vivo
Naoki Tanimizu [Associate Professor, IMSUT]

18:25-18:30

Instructions
Manabu Ozawa [Associate Professor, IMSUT]

Day2: October 28 (Thu.)
09:25-09:30

Instructions
Manabu Ozawa [Associate Professor, IMSUT]

Session 5 : Molecular mechanisms and techniques-1
09:30-09:45
O-19

Understanding the mechanisms of mitotic spindle assembly and positioning using advanced
genetic and optogenetic technologies
Tomomi Kiyomitsu [Assistant Professor, OIST]

09:45-10:00
O-20

CRMP/UNC-33 organizes microtubule bundles for KIF5-mediated mitochondrial distribution
to axon
Chan-Yen Ou [Assistant Professor, IBMB]

10:00-10:15
O-21

Functional tissue formation from pluripotent stem cells by multicellular autonomy
Mototsugu Eiraku [Professor, INFRONT]

10:15-10:30
O-22

Dynamics of cis-regulatory elements interactome during lineage specification maps target
genes to disease-associated non-coding DNA elements
Xin Liu [Primary Investigator, SIBCB]

10:30-10:45
O-23

Live imaging of taste cells in action
Myunghwan Choi [Associate Professor, IMBG]

10:45-10:55

BreakSession 6 : Molecular mechanisms and techniques-2

6

Chair: Jiaquan Liu [Principal Investigator, SIBCB]

12:10-13:25

Lunch

13:25-14:45

Young Scientist Session/Student Session at Zoom breakout room
Young Scientist Session: Breakout room 1
Student Session: Breakout room 2

14:45-15:00

Break

15:00-17:00

Poster discussion at Remo, virtual event platform

17:00-17:10

Instructions of voting for Best Presenter/Discusser Award
Manabu Ozawa [Associate Professor, IMSUT]

     -18:30

Deadline for voting

Day3: October 29 (Fri.)
09:25-09:30

Instructions
Manabu Ozawa [Associate Professor, IMSUT]

Session 7 : Inflammation, infection and immunity

Chair: Guangchuan Wang [Professor, SIBCB]

09:30-09:45
O-29

Essential roles of chaperone proteins in controlling type I IFN interferon induction
Helene Minyi Liu [Associate Professor, IBMB]

09:45-10:00
O-30

SARS-CoV-2 RNA polymerase: Structure, function and inhibition
Quan Wang [Assistant Professor, SIAIS, ShanghaiTech University/National Center forProtein Science, Shanghai (NCPSS)]

10:00-10:15
O-31

Molecular mechanism of glycan receptor recognition by mumps virus
Takao Hashiguchi [Professor, INFRONT]

10:15-10:30
O-32

A capsid with a twist: Assembly mechanism of the pleomorphic immature poxvirus scaffold
Matthias Wolf [Professor, OIST]

10:30-10:40

Break

10:40-10:50

Memorial of Ken-ichi Arai
Makoto Nakanishi [Vice Dean/Professor, IMSUT]

10:50-11:35

Ken-ichi Arai Award Lecture
Physiological roles and molecular mechanisms of autophagy-dependent and independentdegradation systems in vertebrates
Hideaki Morishita [Lecturer, Juntendo University Graduate School of Medicine]

11:35-11:45

Break

Chair: Lan-Tao Gou [Principal Investigator, SIBCB]

10:55-11:10
O-24

Enzymes' behavior in highly crowded membrane-less compartments
Paola Laurino [Assistant Professor, OIST]

11:10-11:25
O-25

Mapping epitranscriptome of full-length single RNA molecules
Hyeshik Chang [Assistant Professor, IMBG]

11:25-11:40
O-26

MutS stimulates the MutL-DNA binding to load a MutL sliding clamp on DNA
Jiaquan Liu [Principal Investigator, SIBCB]

11:45-12:05

Award ceremony of Best Presenter/Discusser Award
Yuji Yamanashi [Dean/Professor, IMSUT]

11:40-11:55
O-27

Dynamic DNA shortening by telomere binding protein Cdc13
Jing-Jer Lin [Professor, IBMB]

12:05-12:15

Greetings from next host institution
Haitao Yang [Executive Director, SIAIS, ShanghaiTech University]

11:55-12:10
O-28

Structural dissection of human glucose transporter folding reveals evolutionary balancing
between foldability and functionality
Tae-Young Yoon [Professor, IMBG]

12:15-12:20

Closing remarks
Makoto Nakanishi [Vice Dean/Professor, IMSUT]

The 27th East Asia Joint Symposium

The 27th East Asia Joint Symposium7