PERIOFLOW®

On Natural Teeth

CLINICAL EVIDENCE
Edition 2022

CLINICAL BENEFITS

Removes biofilm from periodontal pocket 4 to 9 mm deep1–9
Maintains health of residual periodontal pockets1–3,9during supportive periodontal therapy(SPT).2–14
Decreases bleeding on probing(BOP).3–8,11,14–17
Significantly reduces probing
pocket depth (PPD).2,3,5–9,11–
15,17,18

Promotes the re-attachment ofperiodontal ligament fibroblasts.19

Increases clinical attachment level (CAL).3,5,7,8,11,14,16,18
Preserves cementum in a minimally invasive way(94%),20 dentine19 and soft tissues.1,2
Can be used in patients with aggressive periodontitis
with systemic antibiotics.16
Reduces full-mouth plaque scores.8,11,16
Decreases in Gingival Crevicular Fluid (GCF).7
Effectively improves clinical outcomes during active
periodontal therapy.14

MICROBIOLOGICAL BENEFITS
AA (Aggregatibacter Actinomycetemcomitans)2,7,19
greater reduction than PIEZON®2Red complex bacteria: P. gingivalis,1,4–7,11,12,19T. forsythia,1,2,4–7,12,19 T. denticola,2,4,7,12,19 Orange
complex bacteria.7

Subgingival AIR-FLOWING® can reduce periopathogenic
bacteria and support antimicrobial therapy.21

IN ACCORDANCE WITH THE GUIDED BIOFILM THERAPY (GBT) PROTOCOLPERIOFLOW® is efficient2,3,5,9,10,19 and can be appliedsafely following EMS treatment recommendations.1–
6,8,9,11,14–18,22

Time-efficient compared to traditional methods.2–
4,13,14,16,17

More comfortable with high patient compliance than
traditional methods1–10,13,14,16 based on Visual Analog
Scale (VAS).23

CONSENSUS
Academics and clinicians alike reached a common
consensus on safety, efficiency and comfort25,26 using
PERIOFLOW®.

Local periodontal treatment with AIR-FLOWING® is apromising approach to reduce thebacterial penetration into thebloodstream during periodontal
treatment.24

PERIOFLOW® On Natural Teeth

1.

Randomized controlled trial assessing efficacy and safety ofglycine powder air polishing in moderate-to-deep periodontal
pockets. Flemmig, T. F. et al. Journal of periodontology 83, 444–52(2012).

14.

Efficacy of erythritol powder air-polishing in active and supportive
periodontal therapy: A systematic review and meta-analysis.
Abdulbaqi, H. R. et al. International journal of dental hygiene 20, 62–74 (2022).

2.

Subgingival air-polishing with erythritol during periodontal
maintenance: randomized clinical trial of twelve months. Müller,N., Moëne, R., Cancela, J. A. & Mombelli, A. Journal of clinicalperiodontology 41, 883–9 (2014).

15.

One-Stage Full Mouth Instrumentation (OSFMI): Clinical
Outcomes of an Innovative Protocol for the Treatment of Severe
Periodontitis. Mensi, M. et al. Journal of the International Academyof Periodontology 22, 129–136 (2020).

3.

Clinical outcomes following subgingival application of a novel
erythritol powder by means of air polishing in supportive
periodontal therapy: a randomized, controlled clinical study. Hägi,T. T., Hofmänner, P., Salvi, G. E., Ramseier, C. A. & Sculean, A.
Quintessence international (Berlin, Germany : 1985) 44, 753–61.

16.

Efficacy of subgingival air polishing in patients with aggressive
periodontitis. Trtić, N., Bošnjak, A., Arbutina, R., Kojić, Ž. &Veselinović, V. Balkan Journal of Dental Medicine 20, 149–154(2016).

4.

Subgingival plaque removal using a new air-polishing device.
Moëne, R., Décaillet, F., Andersen, E. & Mombelli, A. Journal ofperiodontology 81, 79–88 (2010).

17.

Comparison of three full-mouth concepts for the non-surgicaltreatment of stage III and IV periodontitis: A randomized controlled
trial. Stein, J. M. et al. Journal of clinical periodontology 48, 1516–
1527 (2021).

5.

The effects of erythritol air-polishing powder on microbiologic andclinical outcomes during supportive periodontal therapy: Sixmonth results of a randomized controlled clinical trial. Hägi, T. T.
et al. Quintessence international (Berlin, Germany : 1985) 46, 31–41(2015).

18.

Infection Control in Adult Periodontal Patients Using UltrasonicDebridement and Erythritol Powder: A Randomized, Controlled,
Split-Mouth Clinical Study. Cardaropoli, D., Albano, M. &Tamagnone, L. The International journal of periodontics &restorative dentistry 41, 675–681 (2021).

6.

Subgingival debridement of periodontal pockets by air polishing incomparison with ultrasonic instrumentation during maintenancetherapy. Wennström, J. L., Dahlén, G. & Ramberg, P. Journal ofclinical periodontology 38, 820–7 (2011).

19.

7.

Clinical and Microbiological Study about Efficacy of Air-polishingand Scaling and Root-planing. Yang, K.-I., Park, D.-Y., Kim, B.-O. &Yu, S.-J. International Journal of Oral Biology 40, 93–101 (2015).

A Biofilm Pocket Model to Evaluate Different Non-Surgical
Periodontal Treatment Modalities in Terms of Biofilm Removaland Reformation, Surface Alterations and Attachment ofPeriodontal Ligament Fibroblasts. Hägi, T. T. et al. PloS one 10,
e0131056 (2015).

20.

8.

Adjunctive air-polishing with erythritol in nonsurgical periodontal
therapy: a randomized clinical trial. Jentsch, H. F. R., Flechsig, C.,
Kette, B. & Eick, S. BMC oral health 20, 364 (2020).

Preservation of root cementum: a comparative evaluation ofpower-driven versus hand instruments. Bozbay, E. et al.
International journal of dental hygiene 16, 202–209 (2018).

21.

9.

Maintenance therapy for teeth and implants. Mombelli, A.
Periodontology 2000 79, 190–199 (2019).

Antimicrobial Impact of Different Air-Polishing Powders in a
Subgingival Biofilm Model. Wenzler, J.-S. et al. Antibiotics (Basel,Switzerland) 10, (2021).

22.

10.

Full Mouth-Erythritol Powder Air Polishing Therapy (FM_EPAPT):
Paradigm Shift. Il nuovo modo di concepire la terapia. Mensi, M.
Quintessence International 32, 119–122 (2016).

Efficacy of the additional use of subgingival air polishing witherythritol powder in the treatment of periodontitis patients: arandomized controlled clinical trial. Mensi, M. et al. Clinical oral
investigations 25, 729–736 (2021).

11.

Clinical and microbiological effects of the supplementary use ofan erythritol powder air-polishing device in non-surgicalperiodontal therapy: A randomized clinical trial. Park, E. J. et al.
Journal of Periodontal and Implant Science 48, 295–304 (2018).

23.

A 12-month randomized controlled trial evaluating erythritol airpolishing versus curette/ultrasonic debridement of mandibular
furcations in supportive periodontal therapy. Ulvik, I. M. et al. BMC
oral health 21, 38 (2021).

12.

Clinical and microbiological effect of frequent subgingival airpolishing on periodontal conditions: a split-mouth randomized
controlled trial. Sekino, S., Ogawa, T., Murakashi, E., Ito, H. &Numabe, Y. Odontology 108, 688–696 (2020).

24.

Influence of periodontal treatment on blood microbiotas: a clinical
trial. Zhang, W., Meng, Y., Jing, J., Wu, Y. & Li, S. PeerJ 9, e10846(2021).

25.

A paradigm shift in mechanical biofilm management? Subgingival
air polishing: a new way to improve mechanical biofilm
management in the dental practice. Sculean, A. et al. Quintessence
international (Berlin, Germany : 1985) 44, 475–7 (2013).

26.

Consensus Conference Findings on Supragingival and Subgingival
Air Polishing. Cobb, C. M. et al. Compendium of continuing
education in dentistry (Jamesburg, N.J. : 1995) 38, e1–e4 (2017).

13.

Use of air polishing for supra- and subgingival biofilm removal fortreatment of residual periodontal pockets and supportive
periodontal care: a systematic review. Nascimento, G. G., Leite, F.
R. M., Pennisi, P. R. C., López, R. & Paranhos, L. R. Clinical oral
investigations 25, 779–795 (2021).

Benefit from SDA training:swissdentalacademy.com

FA-709 EN Rev. C Ed. 03/2022

References