1/5

RNase Inhibitor Recombinant type
Code: SIN-201, 229, 259
Jan. 6, 2017
SDS No.1119F

Safety Data Sheet
1 Chemical product and company identification
Identification of the productProduct Code
SUPPLIERNameAddress

RNase Inhibitor Recombinant type
SIN-201, 229, 259
TOYOBO Co., Ltd.
2-2-8 Dojima Hama Kita-ku Osaka, 530-8230 Japan

Biotech support Department
Department+81-6-6348-3786
Emergency Telephone No.
+81-6-6348-3833
Fax No.
Recommended use and restrictions on Stabilization of RNA (Reagent for research)use

2 HAZARDS IDENTIFICATION
Most Important Hazards
GHS Classification
Hazard class and category
Physical Hazards
Health Hazards
Acute Toxicity
Skin corrosion/Irritation
Serious eye damage/Eye irritation
Environmental Hazards
Label elements
RNase Inhibitor Recombinant type
Pictograms or symbols
Signal word
Hazard statements
Precautionary statement(s)Prevention
Response

Few adverse human health effects are anticipated.
Classification not possible
Classification not possible
Category 3

Category 2B
Classification not possible―Warning
Causes mild skin irritation.Causes eye irritation.
Wash hands thoroughly after handling.
If skin irritation occurs: Get medical advice / attention.
If in eyes: Rinse cautiously with water for several
minutes. Remove contact lenses, if present and easy todo. Continue rinsing. If eye irritation persists: Get
medical advice / attention.

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RNase Inhibitor Recombinant type
Code: SIN-201, 229, 259
Jan. 6, 2017
SDS No.1119F

Safety Data Sheet
3 COMPOSITION / INFORMATION ON INGREDIENTS
Chemical Product(Substance/Mixture)
Chemical Nature
Parts Name
RNase Inhibitor Recombinant type

MixtureAqueous solution of enzyme,Main components
HEPES
Ribonuclease Inhibitor
GlycerolPotassium chloride
Dithiothreito
Polyoxyethylene Sorbitan
Monolaurate
Components Contributing to the Hazard
GlycerolCommon Chemical Name(or Generic Name)
Glycerin
Synonyms
Contained Parts:Percentage
50%
Chemical formula
CH2OHCHOHCH2OH

CAS No. (EC NO.)7365-45-9
56-81-57447-40-7
3483-12-3
9005-64-6

56-81-5

CAS No.

4 FIRST-AID MEASURES
Inhalation

Skin Contact
Eye Contact
Ingestion

In case of irritation by inhaling this product, moveaffected person to fresh air and await recovery. Ifirritation persists, seek immediate medical attention.
Wash with clean water, immediately.
Rinse cautiously with water for several minutes.
Induce vomiting.
If indisposition continues, seek medical attention.

5 FIRE-FIGHTING MEASURESExtinguishing Media
Protection of fire-fighters

Water, Carbon Dioxide, Foam, Dry Chemical Powder
Fire-fighting should be done from the windward side offire area.Fire-fighters should wear proper protective
equipment in case of large scale fire.

6 ACCIDENTAL RELEASE MEASURES
Personal Precautions
Environmental Precautions
Methods for Cleaning up

Wear protective gear to avoid eye/skin contact andinhalation.
Avoid disposition to the environment.
Use cloth, paper or anything similar to soak up thesolution leaking out of the container.

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RNase Inhibitor Recombinant type
Code: SIN-201, 229, 259
Jan. 6, 2017
SDS No.1119F

Safety Data Sheet
7 HANDLING AND STORAGE
HANDLING
Technical Measures
Precautions
Safe Handling Advice
STORAGE
Storage Conditions
Packaging Materials

Wear protective equipments and avoid contact witheyes and skin. Handle with ventilation and local
After handling, wash with clean water.
Good laboratory technique should be used whenhandling this product.
Store at about -20°C
Store in the original package

8 EXPOSURE CONTROLS/ PERSONAL PROTECTION
ENGINEERING MEASURES
Control Parameter
Limit Values
JSOH OELACGIH TLVOSHA PEL

Set up good ventilation and exhaust system in the work
area.
GlycerolNot established
10mg/m3
total dust: 15mg/m3TWA
respirable fr.: 5mg/m3TWAPERSONAL PROTECTIVE EQUIPMENT
Wear a dust mask.
Respiratory Protection
Hand Protection
Chemical safety gloves.
Eye Protection
Chemical safety goggles.
Skin and Body Protection
Long sleeves to prevent contact with skin.

9 PHYSICAL AND CHEMICAL PROPERTIESPhysical State
ColourOdour
pH
Flash Point

Boiling Point
Melting Point
Decomposition TemperatureSpecific gravity
Solubility
n-octanol/water partition coefficientliquid over -20℃.
ColourlessNone
7.0-9.0
Not flammable due to aqueous solution, but glycerol
whose flash point 160°C may stay behind after
volatilization.
No data available
No data available
No data available
1.0-1.2
Soluble in water
Glycerol Pow = -2.66

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RNase Inhibitor Recombinant type
Code: SIN-201, 229, 259
Jan. 6, 2017
SDS No.1119F

Safety Data Sheet
10 STABILITY AND REACTIVITY
StabilityPossible Hazardous Reactions
Conditions to Avoid
Material to Avoid
Hazardous Decomposition ProductStable at -20℃
NoneStrong heat
Direct sunlight, strong oxidizers and strong reducers
No information available

11 TOXICOLOGICAL INFORMATION
Acute Toxicity
Classification not possible
Local Effects
Causes mild skin irritation.Causes eye irritation.
Toxicological information on the component of this product
GlycerolAcute toxicity (LD50)
Oral-mouse: 4090mg/kg
Oral-rat: 12.6g/kg
Skin corrosion/Irritation
Category 3
Category 2B
Serious eye damage/Eye irritation

12 ECOLOGICAL INFORMATIONEcotoxicity
Persistence/Degradability
Bioaccumulative potential
Mobility in soil

No data available
Biodegradable
Thought to be not bioaccumulative.
Soluble in water and diffusible into water environment.

13 DISPOSAL CONSIDERATIONS
Waste from Residues
Contaminated Packaging

Dispose of in accordance with all applicable local andnational laws and regulations.
Dispose of in accordance with all applicable local andnational laws and regulations.

14 TRANSPORT INFORMATIONInternational Regulations
UN Classification Number

Specific Precautions

Not classified
Follow all of the laws and regulations in yourrespective country.
To prevent packages from breaking, handle withcare.Store at about -20°C when it is transported.

15 REGULATORY INFORMATION
Follow all of the laws and regulations in your country.

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RNase Inhibitor Recombinant type
Code: SIN-201, 229, 259
Jan. 6, 2017
SDS No.1119F

Safety Data Sheet
16 OTHER INFORMATION
Notice

The information in this SDS, to the best of ourknowledge, is accurate and correct. However, TOYOBO
makes no warranty and assumes no liability
whatsoever in connection with any use of thisinformation. The information shall not be taken as
being all inclusive and is to be used only a guide. Allmaterials and mixtures may be present unknown
hazards and should be used with caution. The SDS issubject to revision as new information becomes
available.