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Uracil-DNA Glycosylase, Heatlabile <Glycerol Free>First issue : Oct. 2, 2018
Revised : Apr. 1, 2021
SDS No.1559F

Safety Data Sheet
1 CHEMICAL PRODUCT AND COMPANY IDENTIFICATION
Identification of the product

Uracil-DNA Glycosylase, Heat-labile <Glycerol Free>

Product Code
SUPPLIER
Name
Address
Department
Emergency Telephone No.
Fax No.
Recommended use and restrictions on use

UNG-201, 209
TOYOBO Co., Ltd.
2-8 Dojima Hama 2-chome, Kita-ku OSAKA 530-8230 JAPAN
Biotechnology Overseas Sales and Marketing Department+81-6-6348-3843+81-6-6348-3833
decomposition of DNA template containing uracil (Reagent for research)

2 HAZARDS IDENTIFICATION
Important Hazards
Adverse effects on human health
GHS Classification

Few adverse human health effects are anticipated.
Not classified

3 COMPOSITION / INFORMATION ON INGREDIENTS
Chemical Product(Substance/Mixture)
Chemical Nature

MixtureAqueous solution of enzyme
Main components

Uracil DNA glycosylase
Poly(oxyethylene) octylphenyl
Components Contributing to the Hazard
Common Chemical Name
Synonyms
Chemical formula
CAS No.
Concentration

CAS No.
9002-93-1

Poly(oxyethylene) octylphenyl ether
Triton X-100
HO(C2H4O)n-C6H4-C8H179002-93-1
0.1%

4 FIRST-AID MEASURES
Inhalation
Skin Contact
Eye Contact
Ingestion

In case of irritation by inhaling this product, remove person to fresh airand keep comfortable. Seek medical attention.
Wash with clean water, immediately.
Rinse cautiously with water for several minutes. If eye irritation persists:
Get medical advice / attention.
Rinse mouth. Call a POISON CENTER or doctor/physician if you fell
unwell. Do not induce to vomiting.

5 FIRE-FIGHTING MEASURESExtinguishing MediaSpecific extinguishing methods
Protection of fire-fighters

Water, Carbon Dioxide, Foam, Dry Chemical Powder
Fire-fighting should be done from the windward side of fire area.
Fire-fighters should wear proper protective equipment in case of large
scale fire.

6 ACCIDENTAL RELEASE MEASURES
Personal precautions, protective
equipment, and emergency procedure

Wear protective equipment to avoid eye/skin contact and inhalation.

Environmental Precautions
Methods and materials for containment
and methods and materials for cleaning

Avoid disposition to the environment.
Use cloth, paper or anything similar to soak up the solution leaking out ofthe container. Take up under vacuum using dust collecting filter.

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Uracil-DNA Glycosylase, Heatlabile <Glycerol Free>First issue : Oct. 2, 2018
Revised : Apr. 1, 2021
SDS No.1559F

Safety Data Sheet
7 HANDLING AND STORAGE
Handling 〈precautions for safe handling〉
Technical Measures
Wear protective equipments and avoid contact with eyes and skin.
Precautions 〈local/total ventilation〉
Prevention of contact
Hygiene measures
Storage 〈conditions for safe storage〉
Technical Measures
Incompatible substances and mixtures
Packaging Materials

Good laboratory technique should be used .
Avoid contact with oxidizers.
After handling, wash with clean
Keep tightly closed and store below -15℃
Oxidizers
Store in the original package

8 EXPOSURE CONTROLS AND PERSONAL PROTECTION
Personal protective equipment
Respiratory Protection
Hand Protection
Eye Protection
Skin and Body Protection

Wear a dust mask.
Chemical safety gloves.
Chemical safety goggles.
Long sleeves to prevent contact with skin.

9 PHYSICAL AND CHEMICAL PROPERTIES
Physical State, Form, Colour
Odour
pH
Flash Point
Boiling Point
Melting Point
Decomposition TemperatureSpecific gravity
Solubility

Liquid （Solid at -20℃ or below）, ColourlessNone
7.0-9.0
Not flammable due to aqueous solution.
Not available
Not available
Not available
1.0-1.2
Soluble in water

10 STABILITY AND REACTIVITY
Chemical stability and hazardous
reactions

Conditions to Avoid
Incompatible materials
Hazardous decomposition products

Stable at -20±5℃. Decomposes gradually at normal temperature, but notdangerous reaction.
Strong heat, Direct sunlight
Strong oxidizers, Strong reducers
Not available

11 TOXICOLOGICAL INFORMATION
Acute Toxicity

Not available

May cause skin irritation.
Skin irritation/corrosion
May cause eye irritation.
Eye damage/irritation
Specific target organ toxicity-single exposure May cause respiratory irritation.
Toxicological information on the component of this product
Poly(oxyethylene) octylphenyl ether
Acute toxicity
Oral-rat:
LD50 1800mg/kg
Dermal-rabbit:
LD50 >3000mg/kg
Skin corrosion/Irritation
Not available
Eye damage/irritation
Category 2ACarcinogenicity
Not available
Not available
Specific target organ toxicity-repeated3/3

Uracil-DNA Glycosylase, Heatlabile <Glycerol Free>First issue : Oct. 2, 2018
Revised : Apr. 1, 2021
SDS No.1559F

Safety Data Sheet
12 ECOLOGICAL INFORMATION
Ecotoxicity
Persistence and degradability
Bioaccumulative potential
Mobility in soil
Other adverse effects

Poly(oxyethylene) octylphenyl ether
Fish (Bluegill) : LC50 (96hr) 3mg/L
Rapidly biodegradable.
Not available

Soluble in water and diffusible into water environment.
Not available

13 DISPOSAL CONSIDERATIONS
Waste from Residues
Contaminated container andContaminated packaging

Dispose of in accordance with all applicable local and national laws andregulations.
Dispose of in accordance with all applicable local and national laws andregulations.

14 TRANSPORT INFORMATIONInternational Regulations
UN Classification Number
Specific Precautions

Not classified
Follow all of the laws and regulations in your respective country.
To prevent packages from breaking, handle with care.

15 REGULATORY INFORMATION
Follow all of the laws and regulations in your country.
REACH - Candidate List of Substances of Very High Concern for
Authorisation (Article 59).: p-tertiary-Octylphenoxy polyethyl alcoholThis product contains a substance listed on Annex XIV of the REACH
Regulation (EC) Nr. 1907/2006.
Listed substance / Sunset Date: p-tertiary-Octylphenoxy polyethyl alcohol/ 04.01.2021

16 OTHER INFORMATION
Notice

The information in this SDS, to the best of our knowledge, is accurate andcorrect. However, TOYOBO makes no warranty and assumes no liability
whatsoever in connection with any use of this information.
The SDS is subject to revision as new information becomes available.