Workshop #1 Report – EDAR7

Workshop #1
Environmental Dimensions of AMR
in Asia-Pacific LMICs
Part 1: Priority research needs in Asian LMICs
Part 2: Regional Guideline for AMR surveillancein the Animal Farm Environment

Jointly organized by:1

Workshop #1: Part 1 - Frontlines on environmental AMR studies in Asian LMICs
Dr. Kwanrawee
Sirikanchana

Dr. Sulfikar

Universitas Negeri
Makasar, Indonesia

Chulabhron ResearchInstitute, Thailand••

Fostering collaboration in Research, Funding, and Policy.
AMR surveillance framework in Thailand: resource
allocation, targeted bacteria, genetic monitoring,stakeholder roles, antibiotic consumption, andcontinuous data updates.

••••

Dr. Toru Watanabe
Yamagata University,JapanDr. Bing Li

Tsinghua University,China••••

ARGs and their mobility in Environment-HumanAnimalConstructing analysis pipelines
Fostering collaboration networks in all sectors
Conducting AMR risk assessments

High prevalence of AMR (pneumonia and sepsis, 60% resistanceto cephalosporins)
Misuse and overuse of antimicrobials
Limited diagnostic infrastructure and human resources,
Lacking of enforcement of the policies (gap between ministries)••

High AMR in Floating house areas - inadequate sanitation
infrastructure (direct disposal of human and animal waste into
the surrounding water).
Seasonal change in Sanitation conditions - distinct changes inwater levels between low and high seasons

WS #1: Part 1 – Online Poll on Research Needs in Asian LMICs[Q1] What targets need further research and understanding particularly in
Asian LMICs?
RiskAssessment

1-1. Sources [High priority]
1-1. Sources [Highest priority]

Sources

OthersWild/migrant animals
Aquaculture industry
Pharmaceutical industry
Urban wastewater
Hospitals
Livestock industry

Ecological risk
Assessment model andindicator - human health
Exposure route - humanhealth
Dose-response relationship- human health

0Reservoirs

1-3. Risk assessment [High priority]
1-3. Risk assessment [Highest priority]

2460

Antimicrobials& other selection
factors

1-2. Reservoirs [High priority]
1-2. Reservoirs [Highest priority]
Others
Sediments

48

1-4. Antimicrobial chemicals and other selection
factors [High priority]
1-4. Antimicrobial chemicals and other selection
factors [Highest priority]
Ecological impacts
Stability in the environment

Biofilms in pipelines

Discharged quantity andcritical sources
Impacts on
selection/enrichment of AMR

Soils
WWTPs
04812048

WS #1 : Part 1 – Poll on Research Needs in Asian LMICs[Q2] What factors or local conditions affecting AMR in the environment
need further research and understanding particularly in Asian LMICs?
Climate & seasons2-1. Climate and seasons [High priority]
2-1. Climate and seasons [Highest priority]
Flood

Clinical & socio-economic

Water supply & sanitation

2-2. Clinical and socio-economical conditions [Highpriority]
2-2. Clinical and socio-economical conditions [Highestpriority]2-3. Water supply and sanitation [High priority]
2-3. Water supply and sanitation [Highest priority]

Wastewater treatment
systems

WaSH practices

Irrigation
Seasonal change

GovernancePrecipitation

Medical treatment andstewardship

Impacts of climate change

Policy making

Temperature

Target pathogens andmicrobes

048Drainage andsanitation systems
Water supply systems
04804[Q1] x [Q2] = Priority Research Needs
n Discharge from wastewater, hospitals, livestockn WWTPs as AMR reservoirs
n Exposure route (human) in risk assessmentn Load of antimicrobials & pollutants and theirselection impacts

p Impacts of climate change, temperaturep Concerned pathogens & microbes
p Conditions of WWT systems,drainage/sanitation

8

WS #1 : Part 1 – Panel Discussion: Research Needs in Asian LMICs
Ø Researches for actions are prioritized in Asian LMICs
Ø Data collection with comparable indicators (e.g. E. coli) for understanding of locality
Ø Climate change causes broad impacts on AMR issues in Asian LMICs• safe water availability• patterns of precipitation & flooding (which spreads sewage, animal wastes)• geographical distribution of diseases
Ø We should sort out impacts of climate change on AMR issues in Asian LMICs.
Ø Community-level water supply needs attention
Ø Direct use of surface/groundwaterØ Poorly-maintained household treatment
Ø Use of existing stats on AMU to identify AMR hotspots& vulnerable communities• Modelling/simulation• immediate actionable findings

Workshop Part II: Consultation of Guideline for
AMR MONITORING AND SURVEILLANCE
IN ANIMAL FARM ENVIRONMENT
Workshop Report

Facilitators:
Muhammad Usman Zaheer, Food and Agriculture Organization of the United Nations, Regional Office for Asia and the PacificRoosmarijn Luiken, Utrecht University, Faculty of Veterinary Medicine, the Netherlands

FAO Action Plan on AMR
FAO Action Plan on AMR
Supporting innovation and resiliencein food and agriculture sectors

Purpose of the guidelines and aim of workshop at EDAR
Guide countries on risk-based surveillance, for research and as an add-on to ongoing
AMR surveillance in healthy terrestrial and aquatic animals
Learn from experience andexpertise of participants EDAR AMR
Protecting
occupational healthProtecting public healththrough safe foodReceive feedback on priorities,expertise and implementation
Protecting
the environment

Lessons learnt to translate into
future work
Identify collaborators/ contributors

What happened at the workshop
ü Awareness on FAO’s work inagrifood sectors
ü New connections and collaborators
ü Identification of ongoing work in
the area, test methods, targeted
pathogens and ARGs, data sharing
and data useü Deliberations onpriorities, available expertise andimplementation of surveillance inanimal farm environment

Steps post EDAR

BE A CONTRIBUTOR

Thank You