SAFETY DATA SHEET
according to GB/T 16483 and GB/T 17519

ImmersolTM 518 F

Version 1.0

Material: 000000-0360-890

Revision date: 2024/05/29

Date of last issue: -1. PRODUCT AND COMPANY IDENTIFICATION
Product name:

ImmersolTM 518 F

Product name in English:

ImmersolTM 518 F

Chemical nature:

Halogen-free immersion oil based on ester oil.

Manufacturer or supplier's details
Company: Carl Zeiss Jena GmbH
Address:

Oberkochen location
Carl-Zeiss-Straße 22
D-73447 Oberkochen

Telephone:

Chemical and material engineering+49 7364 20-4599

Telefax:+49 7364 20-4521

E-mail address:

Chemical and material engineering
SDS@zeiss.com

Emergency telephone number :+86-0532-83889090

Recommended use of the chemical and restrictions on use
Recommended use: Industrial use
Professional use
Immersion oil for fluorescence-microscopy, halogen-free, lowfluorescence
2. HAZARDS IDENTIFICATION
Emergency Overview
Appearance
Colour
Odour

:
:
:

liquidcolourlessslight, aromatic

May be harmful if swallowed or in contact with skin. Causes skin irritation. Toxic to aquatic life.
GHS Classification
Acute toxicity (Oral):

Category 5

Acute toxicity (Dermal):

Category 5

Skin corrosion/irritation:

Category 2
1 / 13

SAFETY DATA SHEET
according to GB/T 16483 and GB/T 17519

ImmersolTM 518 F

Version 1.0
Revision date: 2024/05/29

Material: 000000-0360-890
Date of last issue: -Short-term (acute) aquatic
hazard:Category 2

GHS label elements
Hazard pictograms:

Signal word:

Warning

Hazard statements:

H303 + H313 May be harmful if swallowed or in contact withskin.
H315 Causes skin irritation.
H401 Toxic to aquatic life.

Precautionary statements:

Prevention:
P264 Wash skin thoroughly after handling.
P273 Avoid release to the environment.
P280 Wear protective gloves.
Response:
P302 + P352 IF ON SKIN: Wash with plenty of water.
P312 Call a POISON CENTER/ doctor if you feel unwell.
P332 + P313 If skin irritation occurs: Get medical advice/ attention.
P362 + P364 Take off contaminated clothing and wash it before
reuse.
Disposal:
P501 Dispose of contents/ container to an approved waste
disposal plant.

Physical and chemical hazards
Not classified based on available information.
Health hazards
May be harmful if swallowed. May be harmful in contact with skin. Causes skin irritation.
Environmental hazards
Toxic to aquatic life.
Other hazards which do not result in classification
None known.
3. COMPOSITION/INFORMATION ON INGREDIENTS
Substance / Mixture:

MixtureComponents
Chemical name

CAS-No.
2 / 13

Concentration (% w/w)

SAFETY DATA SHEET
according to GB/T 16483 and GB/T 17519

ImmersolTM 518 F

Version 1.0
Revision date: 2024/05/29

Material: 000000-0360-890
Date of last issue: -Adipic acid-di(8-methyl-tricyclo (5.2.1.0.2.6.)
decane) ester
Succinic acid-di(8-methyl-tricyclo (5.2.1.0.2.6.)
decane) ester
benzyl benzoate

195371-10-9>= 30 -< 50195371-13-2>= 30 -< 50

120-51-4>= 10 -< 20

4. FIRST AID MEASURES
General advice:

Remove and wash contaminated clothing before re-use.

If inhaled:

In case of skin contact:

In case of eye contact:

If swallowed:

Most important symptoms
and effects, both acute anddelayedNotes to physician:

In the case of inhalation of aerosol/mist consult a physician if
necessary.
Wash off with soap and plenty of water.
In the case of skin irritation or allergic reactions see a physician.
Immediately flush eye(s) with plenty of water.
If eye irritation persists, consult a specialist.
Rinse mouth.
Do not give anything to drink or eat.
Do NOT induce vomiting.
Get medical attention.
May be harmful if swallowed or in contact with skin.
Causes skin irritation.

:

No information available.

Suitable extinguishing media:

Unsuitable extinguishingmedia
Specific hazards during firefighting:

Carbon dioxide (CO2)
Dry chemical
Foam
Sand
Water spray jet
High volume water jet:

In case of fire formation of carbonoxides and other toxic gases/vapors is possible.

Specific extinguishing methods:

Special protective equipment
for firefighters:

Use water spray to cool unopened containers.
Prevent fire extinguishing water from contaminating surface
water or the ground water system.
In the event of fire, wear self-contained breathing apparatus.

5. FIREFIGHTING MEASURES

6. ACCIDENTAL RELEASE MEASURES
Personal precautions, protec- :tive equipment and emergency procedures

Avoid contact with skin, eyes and clothing.
Ensure adequate ventilation.
Risk of slipping because of leaked / spilled product3 / 13

SAFETY DATA SHEET
according to GB/T 16483 and GB/T 17519

ImmersolTM 518 F

Version 1.0

Material: 000000-0360-890

Revision date: 2024/05/29

Date of last issue: -Environmental precautions:

Do not flush into surface water or sanitary sewer system.
Avoid subsoil penetration.

Methods and materials forcontainment and cleaning up:

Soak up with inert absorbent material.
Clean contaminated surface thoroughly.

Handling
Advice on protection against
fire and explosion:

Keep away from open flames, hot surfaces and sources ofignition.

Advice on safe handling
Avoidance of contact::

Avoid contact with skin and eyes.
Oxidizing agents

Storage
Conditions for safe storage:

Materials to avoid:

Store at room temperature in the original container.
Keep tightly closed.
Keep away from food and drink.
Do not mix with other immersion liquids.

7. HANDLING AND STORAGE

8. EXPOSURE CONTROLS/PERSONAL PROTECTION
Components with workplace control parameters
Contains no substances with occupational exposure limit values.
Personal protective equipment
Respiratory protection: Not required; except in case of aerosol formation.
Eye/face protection: Avoid contact with eyes.
Skin and body protection: Impervious clothing
Hand protection
Remarks

Protective measures
Hygiene measures:

Avoid contact with skin. Wear suitable gloves. Request information on glove permeation properties from the glove
supplier.
Avoid contact with skin, eyes and clothing.
Take off all contaminated clothing immediately.
When using, do not eat, drink or smoke.

::

9. PHYSICAL AND CHEMICAL PROPERTIES
Appearance:

liquidColour:colourless

Odour

:

slight, aromaticpH:

Not applicable
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SAFETY DATA SHEET
according to GB/T 16483 and GB/T 17519

ImmersolTM 518 F

Version 1.0

Material: 000000-0360-890

Revision date: 2024/05/29

Date of last issue: -Boiling point/boiling range:

ca. 320 °C

Flash point:

249 °C
Method: ISO 2592

Vapour pressure:< 0.1 hPa (20 °C)

Density:

1.093 g/cm³ (20 °C)
Method: DIN 51757

Solubility(ies)
Water solubility:

insoluble

Viscosity
Viscosity, kinematic:

445 mm²/s ( 20 °C)
Method: DIN 51562

Reactivity
Chemical stability
Possibility of hazardous reactions
Conditions to avoid:::

No data available
No decomposition if stored and applied as directed.
None known.

:

Incompatible materials
Hazardous decomposition
products
Hazardous decomposition
products::

Keep away from heat.
Keep away from direct sunlight.
Oxidizing agents
In case of fire formation of carbonoxides and other toxic gases/vapors is possible.
None known.

10. STABILITY AND REACTIVITY:

11. TOXICOLOGICAL INFORMATION
Acute toxicity
May be harmful if swallowed or in contact with skin.
Product:
Acute oral toxicity:

Acute toxicity estimate: 3,811 mg/kg
Method: Calculation method

Acute dermal toxicity:

Acute toxicity estimate: 4,993 mg/kg
Method: Calculation method

Components:
Adipic acid-di(8-methyl-tricyclo (5.2.1.0.2.6.) decane) ester:
Acute oral toxicity: LD50 (Rat): > 2,000 mg/kg
5 / 13

SAFETY DATA SHEET
according to GB/T 16483 and GB/T 17519

ImmersolTM 518 F

Version 1.0
Revision date: 2024/05/29

Date of last issue: Method: Directive 96/54/EG, B.1

Acute dermal toxicity:

LD50 (Rabbit): > 2,000 mg/kg
Method: OECD Test Guideline 402

benzyl benzoate:
Acute oral toxicity:

LD50 (Rabbit): 1,680 mg/kg

Acute dermal toxicity:

LD50 (Rabbit): 4,000 mg/kg

Skin corrosion/irritation
Causes skin irritation.
Components:
Adipic acid-di(8-methyl-tricyclo (5.2.1.0.2.6.) decane) ester:Species: Rabbit
Exposure time
: 4hMethod: Directive 92/69/EWG, B.4
Result: Skin irritation
Succinic acid-di(8-methyl-tricyclo (5.2.1.0.2.6.) decane) ester:
Result: Skin irritation
benzyl benzoate:
Species
Exposure time
MethodResult::::Rabbit4h
OECD Test Guideline 404
No skin irritation

Serious eye damage/eye irritation
Not classified based on available information.
Components:
Adipic acid-di(8-methyl-tricyclo (5.2.1.0.2.6.) decane) ester:Species: Rabbit
Result: No eye irritation
Method: Directive 92/69/EWG, B.5
benzyl benzoate:
SpeciesResult
MethodMaterial: 000000-0360-890:::

RabbitNo eye irritation
OECD Test Guideline 405

6 / 13

SAFETY DATA SHEET
according to GB/T 16483 and GB/T 17519

ImmersolTM 518 F

Version 1.0
Revision date: 2024/05/29

Material: 000000-0360-890
Date of last issue: -Respiratory or skin sensitisation
Skin sensitisation
Not classified based on available information.
Respiratory sensitisation
Not classified based on available information.
Components:
Adipic acid-di(8-methyl-tricyclo (5.2.1.0.2.6.) decane) ester:Species: Guinea pig
Method: Richtlinie 96/54/EG, B.6
Result: Does not cause skin sensitisation.
benzyl benzoate:
Test TypeSpecies
MethodResult::::Local lymph node assay (LLNA)
MouseOECD Test Guideline 429
negative

Germ cell mutagenicity
Not classified based on available information.
Components:
Adipic acid-di(8-methyl-tricyclo (5.2.1.0.2.6.) decane) ester:Germ cell mutagenicity : Cytogenetic test (chromosome aberration), chinese hamster:
Assessment
No reference to mutagenic effects. (OECD TG 473)
Ames-Test, salmonella typhimurium: No reference to mutagenic effects. (EEC B 14)
Carcinogenicity
Not classified based on available information.
Reproductive toxicity
Not classified based on available information.
STOT - single exposure
Not classified based on available information.
STOT - repeated exposure
Not classified based on available information.
Components:
Adipic acid-di(8-methyl-tricyclo (5.2.1.0.2.6.) decane) ester:
Repeated dose toxicity : NOAEL oral, rat: 500 mg/kg (Testing period: 28 d, Subsequent
Assessment
observation period: 48 d, OECD TG 407)

7 / 13

SAFETY DATA SHEET
according to GB/T 16483 and GB/T 17519

ImmersolTM 518 F

Version 1.0

Material: 000000-0360-890

Revision date: 2024/05/29

Date of last issue: -Aspiration toxicity
Not classified based on available information.
Further information
Product:
Remarks:

Health injuries are not known or expected under normal use.
Handle in accordance with good industrial hygiene and safety
practice.

Components:
Adipic acid-di(8-methyl-tricyclo (5.2.1.0.2.6.) decane) ester:
Remarks: Handle in accordance with good industrial hygiene and safety
practice.
12. ECOLOGICAL INFORMATION
Ecotoxicity
Components:
Adipic acid-di(8-methyl-tricyclo (5.2.1.0.2.6.) decane) ester:
Toxicity to fish
: LC50 (Cyprinus carpio): > 5.4 mg/l
Exposure time: 96 h
Method: Directive 92/69/EWG C.1
Remarks: No toxicity at the limit of solubility
LC0 (Cyprinus carpio): >= 5.40 mg/l
Exposure time: 96 h
Method: Directive 92/69/EWG C.1
Remarks: No toxicity at the limit of solubility
Toxicity to daphnia and otheraquatic invertebrates:

EC50 (Daphnia (water flea)): > 6.1 mg/l
Exposure time: 48 h
Method: Directive 92/69/EWG C.2
Remarks: No toxicity at the limit of solubility
EC0 (Daphnia (water flea)): >= 6.10 mg/l
Exposure time: 48 h
Method: Directive 92/69/EWG C.2
Remarks: No toxicity at the limit of solubility
NOEC (Daphnia (water flea)): 1.6 mg/l
Exposure time: 504 h
Analytical monitoring: yes
Remarks: chronic toxicity to daphnia
No toxicity at the limit of solubility

8 / 13

SAFETY DATA SHEET
according to GB/T 16483 and GB/T 17519

ImmersolTM 518 F

Version 1.0

Material: 000000-0360-890

Revision date: 2024/05/29
Toxicity to algae/aquaticplantsDate of last issue: :EC50 (Desmodesmus subspicatus (green algae)): > 3.6 mg/l
Exposure time: 72 h
Method: Directive 92/69/EWG C.3
Remarks: No toxicity at the limit of solubility
NOEC (Desmodesmus subspicatus (green algae)): >= 3.6
mg/l
Exposure time: 72 h
Method: Directive 92/69/EWG C.3
Remarks: No toxicity at the limit of solubility

Toxicity to microorganisms:

EC10 (activated sludge): > 1,000 mg/l
Exposure time: 3 hMethod: EG L133/118 (5.88)
Remarks: to respiration inhibition test applies EC50
No toxicity at the limit of solubility

Ecotoxicology Assessment
Acute aquatic toxicity:

This product has no known ecotoxicological effects.

Chronic aquatic toxicity:

This product has no known ecotoxicological effects.

benzyl benzoate:
Toxicity to fish:

LC50 (Danio rerio (zebra fish)): 2.32 mg/l
Exposure time: 96 h
Test Type: semi-static test
Method: Directive 67/548/EEC, Annex V, C.1.

:

EC50 (Daphnia magna (Water flea)): 3.09 mg/l
Exposure time: 48 h
Test Type: static test
Method: OECD Test Guideline 202

Toxicity to daphnia and otheraquatic invertebrates

NOEC (Daphnia magna (Water flea)): 0.26 mg/l
Exposure time: 21 DAY
Test Type: semi-static test
Method: OECD Test Guideline 211
Toxicity to algae/aquaticplants:

ErC50 (Pseudokirchneriella subcapitata (green algae)): 0.475
mg/l
Exposure time: 72 h
Test Type: static test
Method: OECD Test Guideline 201

M-Factor (Acute aquatic toxicity)
Toxicity to microorganisms

:

1

:

EC50 (activated sludge): > 10,000 mg/l
Exposure time: 3 hMethod: OECD Test Guideline 209
9 / 13

SAFETY DATA SHEET
according to GB/T 16483 and GB/T 17519

ImmersolTM 518 F

Version 1.0

Material: 000000-0360-890

Revision date: 2024/05/29

Date of last issue: -Persistence and degradability
Components:
Adipic acid-di(8-methyl-tricyclo (5.2.1.0.2.6.) decane) ester:
Biodegradability: Result: Not readily biodegradable.
Biodegradation: 13 %Exposure time: 28 days
Method: Modified Sturm Test
benzyl benzoate:
Biodegradability:

Result: Readily biodegradable.
Biodegradation: 94 %Exposure time: 28 days

Bioaccumulative potential
Components:
Adipic acid-di(8-methyl-tricyclo (5.2.1.0.2.6.) decane) ester:Partition coefficient: n: log Pow: 8.9 (25 °C)
octanol/water
Method: Directive 92/69/EWG A.8
benzyl benzoate:
Partition coefficient: noctanol/water:log Pow: ca. 3.97 (25 °C)

Mobility in soil
Components:
Adipic acid-di(8-methyl-tricyclo (5.2.1.0.2.6.) decane) ester:
Mobility: Remarks: KOC: 50.000 (water, soil)(Method: OECD TG 121)
Other adverse effects
Product:
Additional ecological information:

Should not be released into the environment.
Adequate disposal

Components:
Adipic acid-di(8-methyl-tricyclo (5.2.1.0.2.6.) decane) ester:
Additional ecological infor: Do not discharge into sewerage system, surface water or soil.
mationAdequate disposal

10 / 13SAFETY DATA SHEET
according to GB/T 16483 and GB/T 17519

ImmersolTM 518 F

Version 1.0
Revision date: 2024/05/29
benzyl benzoate:
Additional ecological information

Material: 000000-0360-890
Date of last issue: -:Do not discharge into sewerage system, surface water or soil.

13. DISPOSAL CONSIDERATIONS
Disposal methods
Waste from residues
Contaminated packaging::

In accordance with local and national regulations.
Dispose of as unused product.
Offer rinsed packaging material to local recycling facilities.

:
:
:
:
:
:
:

Not applicableNot applicableNot applicableNot applicableNot applicableNot applicableNot applicable:Not applicable

:
:
:
:
:
:
:
:

Not applicableNot applicableNot applicableNot applicableNot applicableNot applicableNot applicableNot applicable

14. TRANSPORT INFORMATIONInternational Regulations
IATA-DGR
UN/ID No.
Proper shipping nameClass
Subsidiary risk
Packing group
LabelsPacking instruction (cargo
aircraft)Packing instruction (passenger aircraft)
IMDG-CodeUN number
Proper shipping nameClass
Subsidiary risk
Packing group
LabelsEmS Code
Marine pollutant

Transport in bulk according to Annex II of MARPOL 73/78 and the IBC CodeNot applicable for product as supplied.
National Regulations
GB 6944/12268
UN number
Proper shipping nameClass
Subsidiary risk
Packing group
Labels

:
:
:
:
:
:

Not applicableNot applicableNot applicableNot applicableNot applicableNot applicable

11 / 13SAFETY DATA SHEET
according to GB/T 16483 and GB/T 17519

ImmersolTM 518 F

Version 1.0
Revision date: 2024/05/29

Material: 000000-0360-890
Date of last issue: -Special precautions for user
Not applicable
15. REGULATORY INFORMATION
National regulatory information
Measures on the Environmental Administration of New Chemical Substances Registration
Registration/Notification number: 01-0000017636-64
Downstream users need to comply with the conditions of safe use of the chemical, understandthe environmental and health hazard and risk management measures identified on the SDS aswell as the local/national regulations concerning the chemical.

16. OTHER INFORMATION
Revision Date:

2024/05/29

Other information:

Sources of key data used tocompile the Safety Data
Sheet

:

Relevant changes to the previous version are symbolized byvertical bars at the left edge.
complete revisionReg. 1272/2008, Annex VI
TRGS 900
TRGS 903
International dangerous goods regulations
Supplier details

Date format:

Further information

yyyy/mm/dd

Full text of other abbreviations

AIIC - Australian Inventory of Industrial Chemicals; ANTT - National Agency for Transport byLand of Brazil; ASTM - American Society for the Testing of Materials; bw - Body weight; CMR Carcinogen, Mutagen or Reproductive Toxicant; DIN - Standard of the German Institute forStandardisation; DSL - Domestic Substances List (Canada); ECx - Concentration associated with
x% response; ELx - Loading rate associated with x% response; EmS - Emergency Schedule;
ENCS - Existing and New Chemical Substances (Japan); ErCx - Concentration associated with
x% growth rate response; ERG - Emergency Response Guide; GHS - Globally Harmonized System; GLP - Good Laboratory Practice; IARC - International Agency for Research on Cancer; IATA
- International Air Transport Association; IBC - International Code for the Construction andEquipment of Ships carrying Dangerous Chemicals in Bulk; IC50 - Half maximal inhibitory concentration; ICAO - International Civil Aviation Organization; IECSC - Inventory of Existing Chemical Substances in China; IMDG - International Maritime Dangerous Goods; IMO - International
Maritime Organization; ISHL - Industrial Safety and Health Law (Japan); ISO - International Organisation for Standardization; KECI - Korea Existing Chemicals Inventory; LC50 - Lethal Concentration to 50 % of a test population; LD50 - Lethal Dose to 50% of a test population (Median
12 / 13SAFETY DATA SHEET
according to GB/T 16483 and GB/T 17519
Version 1.0

ImmersolTM 518 F

Revision date: 2024/05/29

Material: 000000-0360-890
Date of last issue: -Lethal Dose); MARPOL - International Convention for the Prevention of Pollution from Ships;
n.o.s. - Not Otherwise Specified; Nch - Chilean Norm; NO(A)EC - No Observed (Adverse) EffectConcentration; NO(A)EL - No Observed (Adverse) Effect Level; NOELR - No Observable EffectLoading Rate; NOM - Official Mexican Norm; NTP - National Toxicology Program; NZIoC - New
Zealand Inventory of Chemicals; OECD - Organization for Economic Co-operation and Development; OPPTS - Office of Chemical Safety and Pollution Prevention; PBT - Persistent, Bioaccumulative and Toxic substance; PICCS - Philippines Inventory of Chemicals and Chemical Substances; (Q)SAR - (Quantitative) Structure Activity Relationship; REACH - Regulation (EC) No
1907/2006 of the European Parliament and of the Council concerning the Registration, Evaluation, Authorisation and Restriction of Chemicals; SADT - Self-Accelerating Decomposition Temperature; SDS - Safety Data Sheet; TCSI - Taiwan Chemical Substance Inventory; TDG - Transportation of Dangerous Goods; TECI - Thailand Existing Chemicals Inventory; TSCA - Toxic Substances Control Act (United States); UN - United Nations; UNRTDG - United Nations Recommendations on the Transport of Dangerous Goods; vPvB - Very Persistent and Very Bioaccumulative; WHMIS - Workplace Hazardous Materials Information System
Disclaimer
The information provided in this Safety Data Sheet is correct to the best of our knowledge, information and belief at the date of its publication. The information given is designed only as a guidance for safe handling, use, processing, storage, transportation, disposal and release and is not
to be considered a warranty or quality specification. The information relates only to the specificmaterial designated and may not be valid for such material used in combination with any othermaterials or in any process, unless specified in the text.
CN / EN

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