Tetrahydrofuran

US Research Nanomaterials, Inc.

www.us-nano.com

SAFTY DATA SHEET
Revised Date 07/11/2021

1. PRODUCT AND COMPANY IDENTIFICATION
1.1 Product identifiers
Product name: Tetrahydrofuran (THF)
Product Number : N/A
Tetrahydrofuran CAS#: 109-99-9

1.2 Relevant identified uses of the substance or mixture and uses advised against
Identified uses : Research, synthesis of nanomaterial dispersions

1.3 Details of the supplier of the safety data sheet
Company: US Research Nanomaterials, Inc.
3302 Twig Leaf Lane
Houston, TX 77084
USATelephone: +1 832-460-3661
Fax: +1 281-492-8628

1.4 Emergency telephone number
Emergency Phone # : (832) 359-7887

2. HAZARDS IDENTIFICATION
2.1 Classification of the substance or mixture
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
Flammable liquids (Category 2), H225
Acute toxicity, Oral (Category 4), H302
Eye irritation (Category 2A), H319
Carcinogenicity (Category 2), H351
Specific target organ toxicity - single exposure (Category 3), Respiratory system, Central nervous system,
H335, H336
For the full text of the H-Statements mentioned in this Section, see Section 16.
2.2 GHS Label elements, including precautionary statements

PictogramSignal wordDanger

Hazard statement(s)H225 Highly flammable liquid and vapor.
H304 May be fatal if swallowed and enters airways.
H315 Causes skin irritation.
H336 May cause drowsiness or dizziness.
H361 Suspected of damaging fertility or the unborn child.
H373 May cause damage to organs through prolonged or repeated exposure.
H401 Toxic to aquatic life.
Precautionary statement(s)P201 Obtain special instructions before use.
P202 Do not handle until all safety precautions have been read and understood.
P210 Keep away from heat/sparks/open flames/hot surfaces. No smoking.
P233 Keep container tightly closed.
P240 Ground/bond container and receiving equipment.
P241 Use explosion-proof electrical/ ventilating/ lighting/ equipment.
P242 Use only non-sparking tools.
P243 Take precautionary measures against static discharge.
P260 Do not breathe dust/ fume/ gas/ mist/ vapors/ spray.
P264 Wash skin thoroughly after handling.
P271 Use only outdoors or in a well-ventilated area.
P273 Avoid release to the environment.
P280 Wear protective gloves/ protective clothing/ eye protection/ face protection.
P301 + P310 IF SWALLOWED: Immediately call a POISON CENTER/doctor.
P303 + P361 + P353 IF ON SKIN (or hair): Take off immediately all contaminated clothing. Rinse skin withwater/shower.
P304 + P340 + P312 IF INHALED: Remove person to fresh air and keep comfortable for breathing. Call aPOISON CENTER/doctor if you feel unwell.
P308 + P313 IF exposed or concerned: Get medical advice/ attention.
P331 Do NOT induce vomiting.
P332 + P313 If skin irritation occurs: Get medical advice/ attention.
P362 Take off contaminated clothing and wash before reuse.
P370 + P378 In case of fire: Use dry sand, dry chemical or alcohol-resistant foam to extinguish.
P403 + P233 Store in a well-ventilated place. Keep container tightly closed.
P403 + P235 Store in a well-ventilated place. Keep cool.
P405 Store locked up.
P501 Dispose of contents/ container to an approved waste disposal plant.
2.3 Hazards not otherwise classified (HNOC) or not covered by GHS
May form explosive peroxides.

3. COMPOSITION/INFORMATION ON INGREDIENTS
3.1 Substances
Formula : C4H8O
Molecular weight : 72.11 g/molCAS-No. : 109-99-9

EC-No.: 203-726-8
Index-No. : 603-025-00-0

4. FIRST AID MEASURES
4.1 Description of first aid measures
General advice

Show this material safety data sheet to the doctor in attendance.
If inhaled
If breathed in, move person into fresh air. If not breathing, give artificial respiration. Consult a physician.
In case of skin contact
Wash off with soap and plenty of water. Consult a physician.
In case of eye contact
Rinse thoroughly with plenty of water for at least 15 minutes and consult a physician.
If swallowed
Do NOT induce vomiting. Never give anything by mouth to an unconscious person. Rinse mouth withwater. Consult a physician.

4.2 Most important symptoms and effects, both acute and delayed
The most important known symptoms and effects are described in the labeling (see section 2.2) and/or insection 11

4.3 Indication of any immediate medical attention and special treatment needed
no data available

5. FIREFIGHTING MEASURES
5.1 Extinguishing media
Suitable extinguishing media

Carbon dioxide (CO2) Foam Dry powder.
Unsuitable extinguishing media
For this substance/mixture no limitations of extinguishing agents are given.
5.2 Special hazards arising from the substance or mixture
Carbon oxides
Combustible.
Pay attention to flashback.
Vapors are heavier than air and may spread along floors.
Development of hazardous combustion gases or vapors possible in the event of fire.
Forms explosive mixtures with air at ambient temperatures.
5.3 Advice for firefighters
Stay in danger area only with self-contained breathing apparatus. Prevent skin contact by keeping a safe
distance or by wearing suitable protective clothing.
5.4 Further information
Remove container from danger zone and cool with water. Prevent fire extinguishing water fromcontaminating surface water or the ground water system.

6. ACCIDENTAL RELEASE MEASURES

6.1 Personal precautions, protective equipment and emergency procedures
Advice for non-emergency personnel: Do not breathe vapors, aerosols. Avoid substance contact. Ensure
adequate ventilation. Keep away from heat and sources of ignition. Evacuate the danger area, observe
emergency procedures, consult an expert. For personal protection see section 8.
6.2 Environmental precautions
Do not let product enter drains.

6.3 Methods and materials for containment and cleaning up
Cover drains. Collect, bind, and pump off spills. Observe possible material restrictions (see sections 7and 10). Take up carefully with liquid-absorbent material. Dispose of properly. Clean up affected area.
6.4 Reference to other sections
For disposal see section 13.

7. HANDLING AND STORAGE
7.1 Precautions for safe handlingWork under hood. Do not inhale substance/mixture. Avoid generation of vapors/aerosols.
Advice on protection against fire and explosion
Keep away from open flames, hot surfaces and sources of ignition. Take precautionary measures against
static discharge.
Hygiene measures
Immediately change contaminated clothing. Apply preventive skin protection. Wash hands and faceafter working with substance. For precautions see section 2.2.
7.2 Conditions for safe storage, including any incompatibilities
Keep container tightly closed in a dry and well-ventilated place. Keep away from heat and sources ofignition.
Test for peroxide formation periodically and before distillation. Storage class (TRGS 510): 3: Flammableliquids7.3 Specific end use(s)Apart from the uses mentioned in section 1.2 no other specific uses are stipulated

8. EXPOSURE CONTROLS/PERSONAL PROTECTION
8.1 Control parameters
Components with workplace control parameters

8.2 Exposure controls
Appropriate engineering controls
Handle in accordance with good industrial hygiene and safety practice. Wash hands before breaks and at
the end of workday.
Personal protective equipment
Eye/face protection
Safety glasses with side-shields conforming to EN166 Use equipment for eye protection tested andapproved under appropriate government standards such as NIOSH (US) or EN 166(EU).
Skin protection

Handle with gloves. Gloves must be inspected prior to use. Use proper glove removal technique (withouttouching glove's outer surface) to avoid skin contact with this product. Dispose of contaminated gloves
after use in accordance with applicable laws and good laboratory practices. Wash and dry hands.
Body Protection
Impervious clothing, flame retardant antistatic protective clothing. The type of protective equipment must
be selected according to the concentration and amount of the dangerous substance at the specificworkplace.
Respiratory protection
Where risk assessment shows air-purifying respirators are appropriate use a full-face respirator withmultipurpose combination (US) or type AXBEK (EN 14387) respirator cartridges as a backup toengineering controls. If the respirator is the sole means of protection, use a full-face supplied airrespirator. Use respirators and components tested and approved under appropriate government
standards such as NIOSH (US) or CEN (EU).
Control of environmental exposure
Do not let product enter drains.

9. PHYSICAL AND CHEMICAL PROPERTIES
9.1 Information on basic physical and chemical propertiesa) Appearance: Form: liquid, clear, colorlessb) Odor: ether-likec) Odor Threshold: no data availabled) pH: ca.7e) Melting point/freezing point: Melting point: -108.44 °C (-163.19 °F) at 1,013.25 hPa - (ECHA)f) Initial boiling point and boiling range: 65 °C 149 °F at 1,013 hPag) Flash point: -21.2 °C (-6.2 °F) - closed cup - DIN 51755 Part 1h) Evaporation rate: no data availablei) Flammability (solid, gas): no data availablej) Upper/lower flammability or explosive limits: Upper explosion limit: 11.8 %(V) - (THF) Lower explosion

limit: 1.8 %(V) - (THF)k) Vapor pressure: 170 hPa at 20.0 °C (68.0 °F)l) Vapor density: ca.2.5 at 25 °C(77 °F) - (Air = 1.0)m) Relative density: 0.88 g/cm3 at 25 °C (77 °F)n) Water solubility: miscibleo) Partition coefficient - noctanol/water: log Pow: 0.45 at 25 °C (77 °F) - Bioaccumulation is not expected.
p) Auto-ignition temperature: 215 °C (419 °F) at 1,013 hPa - DIN 51794q) Decomposition temperature: no data availabler) Viscosity: 0.518 mm2/s at 25 °C (77 °F) s) Explosive properties: no data availablet) Oxidizing properties: no data available

9.2 Other safety information
Surface tension 26.4 mN/m at 25 °C (77 °F)
Relative vapor density ca.2.5 at 25 °C (77 °F) - (Air = 1.0)

10. STABILITY AND REACTIVITY
10.1 Reactivity
Formation of peroxides possible. Vapors may form explosive mixture with air.
10.2 Chemical stability

The product is chemically stable under standard ambient conditions (room temperature) . Stable underrecommended storage conditions. Test for peroxide formation before distillation or evaporation. Testfor peroxide formation or discard after 1 year.
10.3 Possibility of hazardous reactions
Vapors may form explosive mixture with air.
10.4 Conditions to avoid
Heat, flames and sparks. Warming. Moisture.
10.5 Incompatible materials
Strong oxidizing agents, Acids
10.6 Hazardous decomposition products
Peroxides In the event of fire: see section 5

11. TOXICOLOGICAL INFORMATION
11.1 Information on toxicological effects
Acute toxicity

No data available
Skin corrosion/irritation
No data available
Serious eye damage/eye irritation
Causes serious eye irritation.
Respiratory or skin sensitization
No data available
Germ cell mutagenicity
No data available
Carcinogenicity
No data available
Reproductive toxicity
No data available
Aspiration hazard
No data available
Additional Information

To the best of our knowledge, the chemical, physical, and toxicological properties have not beenthoroughly investigated.

12. ECOLOGICAL INFORMATION
12.1 Toxicity
no data available

12.2 Persistence and degradability
Readily biodegradable.

12.3 Bioaccumulative potential
No data available
12.4 Mobility in soil
no data available12.5 Results of PBT and vPvB assessment
PBT/vPvB assessment not available as chemical safety assessment not required/not conducted12.6 Other adverse effects
no data available

13. DISPOSAL CONSIDERATIONS
13.1 Waste treatment methods
ProductBurn in a chemical incinerator equipped with an afterburner and scrubber but exert extra care inigniting as this material is highly flammable. Offer surplus and non-recyclable solutions to a licensed
disposal company. Contact a licensed professional waste disposal service to dispose of this material.
Contaminated packaging
Dispose of as unused product.

14. TRANSPORT INFORMATION
DOT (US)UN number: 2056, Class: 3, Packing group: II
Proper shipping name: Tetrahydrofuran
Reportable Quantity (RQ): 1000 lbs
Poison Inhalation Hazard: No
IMDG

UN number: 2056 Class: 3Packing group: II EMS-No: F-E, S-D
Proper shipping name: TETRAHYDROFURANIATA

UN number: 2056, Class: 3, Packing group: II
Proper shipping name: Tetrahydrofuran

15. REGULATORY INFORMATIONSARA 302 Components

This material does not contain any components with a section 302 EHS TPQ.
SARA 313 Components

The following components are subject to reporting levels established by SARA Title III, Section 313:
SARA 311/312 Hazards
Fire Hazard, Acute Health Hazard, Chronic Health Hazard

16. OTHER INFORMATION
Further information
The above information is believed to be correct but does not purport to be all inclusive and shall be used
only as a guide. The information in this document is based on the present state of our knowledge and isapplicable to the product with regard to appropriate safety precautions. It does not represent anyguarantee of the properties of the product.
Employers should use this information only as a supplement to other information gathered by them, andshould make independent judgment of suitability of this information to ensure proper use and protect thehealth and safety of employees. This information is furnished without warranty, and any use of theproduct not in conformance with this Safety Data Sheet, or in combination with any other product orprocess, is the responsibility of the user.