SAFETY DATA SHEET
according to Regulation (EC) No. 1907/2006
Version 2.1

Material: 000000-0572-364

Immersol Sil 406

Revision date: 04.08.2023

Date of last issue: 27.07.2023

SECTION 1: Identification of the substance/mixture and of the company/undertaking

1.1 Product identifier
Product name:

ImmersolTM Sil 406

Substance name:

Polydimethylsiloxane

1.2 Relevant identified uses of the substance or mixture and uses advised against
Use of the Sub: Life Sciences, Research and Development
stance/Mixture
Industrial and professional use
Immersion fluid, halogen-free
1.3 Details of the supplier of the safety data sheet
Manufacturer/supplier:Address:

Telephone:Carl Zeiss Jena GmbH
Oberkochen location
Carl-Zeiss-Straße 22D-73447 Oberkochen+49 7364 20-0

Technical Information
TelephoneTelefax:::

Chemical and material engineering+49 7364 20-4599+49 7364 20-4521

Product Safety
E-mail address::

Chemical and material engineering
SDS@zeiss.com

1.4 Emergency telephone number
Poisening Control Center:+49 551 19240 (24 hours)

SECTION 2: Hazards identification
2.1 Classification of the substance or mixture
Classification (REGULATION (EC) No 1272/2008)
Not a hazardous substance or mixture according to Regulation (EC) No. 1272/2008.
2.2 Label elements
Labelling (REGULATION (EC) No 1272/2008)
Not applicable.
2.3 Other hazards
None known.
1 / 10SAFETY DATA SHEET
according to Regulation (EC) No. 1907/2006
Version 2.1

Immersol Sil 406

Revision date: 04.08.2023

Material: 000000-0572-364
Date of last issue: 27.07.2023

SECTION 3: Composition/information on ingredients
3.1 Substances
Substance name:

Polydimethylsiloxane:

No hazardous ingredients

Components
Remarks

SECTION 4: First aid measures
4.1 Description of first aid measures
General advice: If symptoms occur or if in doubt, seek medical advice.

If inhaled:

Provide with fresh air.

In case of skin contact:

Remove immediately adhering matter.
Wash off with soap and water.

In case of eye contact:

Immediately flush eye(s) with plenty of water.
If eye irritation persists, consult a specialist.

If swallowed:

Clean mouth with water and drink afterwards plenty of water.
Do NOT induce vomiting.

4.2 Most important symptoms and effects, both acute and delayed
Symptoms: The most important known symptoms and effects are described in section 2 and / or section 11.
4.3 Indication of any immediate medical attention and special treatment neededTreatment: No information available.

SECTION 5: Firefighting measures
5.1 Extinguishing media
Suitable extinguishing media:

Water mist
Dry chemical
Foam
Carbon dioxide (CO2)
Sand2 / 10

SAFETY DATA SHEET
according to Regulation (EC) No. 1907/2006
Version 2.1

Immersol Sil 406

Revision date: 04.08.2023
Unsuitable extinguishingmedia

Material: 000000-0572-364
Date of last issue: 27.07.2023:High volume water jet

5.2 Special hazards arising from the substance or mixture
Specific hazards during fire- : In case of fire formation of hazardous vapors possible.
fighting
In the event of fire and/or explosion do not breathe fumes.
5.3 Advice for firefighters
Special protective equipment
for firefighters
Further information:

In the event of fire, wear self-contained breathing apparatus.

:

Avoid extinguishing water reaching water or ground watersystem.
Dispose extinguishing water according the local, official regulations.

SECTION 6: Accidental release measures
6.1 Personal precautions, protective equipment and emergency procedures
Personal precautions: No special precautions required.
Sweep up to prevent slipping hazard.
6.2 Environmental precautions
Environmental precautions:

Do not let product enter drains.

6.3 Methods and material for containment and cleaning up
Methods for cleaning up: Take up mechanically and dispose of according to the local
legal regulations.
6.4 Reference to other sections
Adequate disposal, For disposal considerations see section 13.

SECTION 7: Handling and storage
7.1 Precautions for safe handling
Advice on safe handling:
Advice on protection against
fire and explosion:Hygiene measures:

No special handling advice required.
Avoid contact with skin and eyes.
Normal measures for preventive fire protection.

When using, do not eat, drink or smoke. Wash hands before
breaks and at the end of workday. Keep working clothes separately.
3 / 10SAFETY DATA SHEET
according to Regulation (EC) No. 1907/2006
Version 2.1

Immersol Sil 406

Revision date: 04.08.2023

Material: 000000-0572-364
Date of last issue: 27.07.2023

7.2 Conditions for safe storage, including any incompatibilities
Requirements for storage: No special storage conditions required. Do not store together
areas and containers
with food.
7.3 Specific end use(s)Specific use(s):Apart from the uses mentioned in section 1 no other specificuses are intended.

SECTION 8: Exposure controls/personal protection
8.1 Control parameters
8.2 Exposure controls
Personal protective equipment
Eye/face protection: Avoid contact with eyes.
Hand protection
Remarks
Skin and body protection
Respiratory protection
Protective measures::::

not required Avoid long and intense contact with the skin
Keep working clothes separately.
Not required; except in case of aerosol formation.
Handle in accordance with good industrial hygiene and safety
practice.

SECTION 9: Physical and chemical properties
9.1 Information on basic physical and chemical properties
Physical state: liquid
Colour: colourless, clear
Odour: odorless
Melting point/range: -50 °C
Flash point:> 300 °C
Method: ISO 2592

Auto-ignition temperature:

410 °C
Method: EN 14522

Decomposition temperature:> 250 °C

pH:ca. 7.0

Viscosity
Viscosity, dynamic:

1,000 mPa s (25 °C)Viscosity, kinematic:ca. 1000 mm²/s
4 / 10SAFETY DATA SHEET
according to Regulation (EC) No. 1907/2006
Version 2.1

Immersol Sil 406

Revision date: 04.08.2023

Material: 000000-0572-364
Date of last issue: 27.07.2023

Solubility(ies)
Water solubility:(20 °C)practically insoluble

Density:ca. 0.97 g/cm³ (25 °C)
Method: DIN 51757

9.2 Other information
No data available

SECTION 10: Stability and reactivity
10.1 Reactivity
No decomposition if used as directed.
10.2 Chemical stability
Stable under normal conditions.
10.3 Possibility of hazardous reactions
Hazardous reactions: None known.
10.4 Conditions to avoid
Conditions to avoid:

None known.

10.5 Incompatible materials
Materials to avoid:

None known.

10.6 Hazardous decomposition products
Hazardous decomposition: > 150 °C
products
small amounts of formaldehyde

SECTION 11: Toxicological information
11.1 Information on hazard classes as defined in Regulation (EC) No 1272/2008
Acute toxicity
Product:
Acute oral toxicity:

LD50 (Rat): > 5,000 mg/kg
Method: value of literature

Acute dermal toxicity:

LD50 (Rat): > 2,008 mg/kg
Method: value of literature

5 / 10SAFETY DATA SHEET
according to Regulation (EC) No. 1907/2006
Version 2.1

Immersol Sil 406

Revision date: 04.08.2023

Material: 000000-0572-364
Date of last issue: 27.07.2023

Skin corrosion/irritation
Product:
Species
MethodResult:::Rabbitvalue of literature
No skin irritation

Serious eye damage/eye irritation
Product:
Species
MethodResult:::Rabbitvalue of literature
No eye irritation

Respiratory or skin sensitisation
Product:
Species
MethodResult:::guinea-pig
value of literature
Not sensitizing.

:

In vitro tests did not show mutagenic effects:

Animal testing did not show any carcinogenic effects.

:

Animal testing did not show any effects on fertility.

:

No data available:

No significant adverse effects were reported

Germ cell mutagenicity
Product:
Germ cell mutagenicity- Assessment
Carcinogenicity
Product:
Carcinogenicity - Assessment
Reproductive toxicity
Product:
Reproductive toxicity - Assessment
STOT - single exposure
Product:
Remarks
STOT - repeated exposure
Product:
Remarks

6 / 10SAFETY DATA SHEET
according to Regulation (EC) No. 1907/2006
Version 2.1

Material: 000000-0572-364

Immersol Sil 406

Revision date: 04.08.2023

Date of last issue: 27.07.2023

Aspiration toxicity
Product:No data available
11.2 Information on other hazards
Further information
Product:Remarks:The product should be handled with the care usual when dealing with chemicals.

SECTION 12: Ecological information
12.1 Toxicity
Product:
Toxicity to fish:

LC50 (Fish): > 1,000 mg/l
Exposure time: 96 hMethod: value of literature
Remarks: > max. solubility in water
NOEC (Oncorhynchus mykiss): > 10,000 mg/l
Method: value of literature
Remarks: 28 dToxicity to daphnia and otheraquatic invertebrates:

EC50 (Daphnia magna (Water flea)): > 0.0001 mg/l
Exposure time: 48 h
Method: value of literature
Remarks: > max. solubility in water
NOEC (Daphnia magna (Water flea)): > 500 mg/l
Method: value of literature
Remarks: 21 dToxicity to algae/aquaticplants:

IC50 (Skeletonema costatum (marine diatom)): > 100,000
mg/l
Exposure time: 72 h
Method: value of literature

12.2 Persistence and degradability
Product:
Physico-chemical removability:

Remarks: The product is not soluble in water.
The product can be eliminated from water by abiotic processes, e.g. adsorption on activated sludge.
7 / 10SAFETY DATA SHEET
according to Regulation (EC) No. 1907/2006
Version 2.1

Immersol Sil 406

Revision date: 04.08.2023

Material: 000000-0572-364
Date of last issue: 27.07.2023

12.3 Bioaccumulative potential
Product:
Bioaccumulation:

Remarks: Bioaccumulation is unlikely.

12.4 Mobility in soil
No data available
12.5 Results of PBT and vPvB assessment
Not relevant
12.6 Endocrine disrupting properties
No data available
12.7 Other adverse effects
Product:Environmental fate andpathways
Additional ecological information:

Adsorbs on soil.

:

Ecological injuries are not known or expected under normaluse.
According to recent experience are no adverse effects in sewage treatment plants to be expected.

SECTION 13: Disposal considerations
13.1 Waste treatment methods
Product:

Can be landfilled or incinerated, when in compliance with localregulations.

Contaminated packaging:

In accordance with local and national regulations.

SECTION 14: Transport information
14.1 UN number or ID numberADR:

Not regulated as a dangerous good

IMDG:Not regulated as a dangerous good

IATA:

Not regulated as a dangerous goodADR:

Not regulated as a dangerous good

IMDG:

Not regulated as a dangerous good

IATA:

Not regulated as a dangerous good

14.2 UN proper shipping name8 / 10SAFETY DATA SHEET
according to Regulation (EC) No. 1907/2006
Version 2.1

Material: 000000-0572-364

Immersol Sil 406

Revision date: 04.08.2023

Date of last issue: 27.07.2023

14.3 Transport hazard class(es)ADR:

Not regulated as a dangerous good

IMDG:

Not regulated as a dangerous goodIATA:

Not regulated as a dangerous goodADR:

Not regulated as a dangerous good

IMDG:

Not regulated as a dangerous good

IATA (Cargo):

Not regulated as a dangerous good

IATA (Passenger):

Not regulated as a dangerous good

14.4 Packing group

14.5 Environmental hazards
Not regulated as a dangerous good
14.6 Special precautions for user
Not applicable
14.7 Maritime transport in bulk according to IMO instruments
Not applicable for product as supplied.

SECTION 15: Regulatory information
15.1 Safety, health and environmental regulations/legislation specific for the substance or mixture
Seveso III: Directive 2012/18/EU of the European Parliament and of the Council on thecontrol of major-accident hazards involving
dangerous substances.

Not applicable15.2 Chemical safety assessment
Not required.

SECTION 16: Other information
Full text of other abbreviations
ADN - European Agreement concerning the International Carriage of Dangerous Goods by Inland
Waterways; ADR - Agreement concerning the International Carriage of Dangerous Goods byRoad; AIIC - Australian Inventory of Industrial Chemicals; ASTM - American Society for the Testing of Materials; bw - Body weight; CLP - Classification Labelling Packaging Regulation; Regulation (EC) No 1272/2008; CMR - Carcinogen, Mutagen or Reproductive Toxicant; DIN - Standardof the German Institute for Standardisation; DSL - Domestic Substances List (Canada); ECHA 9 / 10

SAFETY DATA SHEET
according to Regulation (EC) No. 1907/2006
Version 2.1

Immersol Sil 406

Revision date: 04.08.2023

Material: 000000-0572-364
Date of last issue: 27.07.2023

European Chemicals Agency; EC-Number - European Community number; ECx - Concentration
associated with x% response; ELx - Loading rate associated with x% response; EmS - Emergency Schedule; ENCS - Existing and New Chemical Substances (Japan); ErCx - Concentration associated with x% growth rate response; GHS - Globally Harmonized System; GLP - Good Laboratory Practice; IARC - International Agency for Research on Cancer; IATA - International Air
Transport Association; IBC - International Code for the Construction and Equipment of Ships carrying Dangerous Chemicals in Bulk; IC50 - Half maximal inhibitory concentration; ICAO - International Civil Aviation Organization; IECSC - Inventory of Existing Chemical Substances in China;
IMDG - International Maritime Dangerous Goods; IMO - International Maritime Organization; ISHL- Industrial Safety and Health Law (Japan); ISO - International Organisation for Standardization;
KECI - Korea Existing Chemicals Inventory; LC50 - Lethal Concentration to 50 % of a test population; LD50 - Lethal Dose to 50% of a test population (Median Lethal Dose); MARPOL - International Convention for the Prevention of Pollution from Ships; n.o.s. - Not Otherwise Specified;NO(A)EC - No Observed (Adverse) Effect Concentration; NO(A)EL - No Observed (Adverse) Effect Level; NOELR - No Observable Effect Loading Rate; NZIoC - New Zealand Inventory ofChemicals; OECD - Organization for Economic Co-operation and Development; OPPTS - Officeof Chemical Safety and Pollution Prevention; PBT - Persistent, Bioaccumulative and Toxic substance; PICCS - Philippines Inventory of Chemicals and Chemical Substances; (Q)SAR - (Quantitative) Structure Activity Relationship; REACH - Regulation (EC) No 1907/2006 of the EuropeanParliament and of the Council concerning the Registration, Evaluation, Authorisation and Restriction of Chemicals; RID - Regulations concerning the International Carriage of Dangerous
Goods by Rail; SADT - Self-Accelerating Decomposition Temperature; SDS - Safety Data Sheet;
SVHC - Substance of Very High Concern; TCSI - Taiwan Chemical Substance Inventory; TECI Thailand Existing Chemicals Inventory; TRGS - Technical Rule for Hazardous Substances; TSCA
- Toxic Substances Control Act (United States); UN - United Nations; vPvB - Very Persistent andVery Bioaccumulative
Further information
Other information
Sources of key data used tocompile the Safety DataSheet::Relevant changes to the previous version are symbolized byvertical bars at the left edge.
Reg. 1272/2008, Annex VI
TRGS 900
TRGS 903
International dangerous goods regulations
Supplier details

The information in this safety sheet is based on the data available at the time of compilation andis intended to describe the product with respect to the precautions to be taken in its use. This information is provided without any guarantee of the properties specified.
MT / EN

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