An Outline of
Niigata University

School of Medicine,
Faculty of Medicine
Graduate School of Medical and Dental
Sciences (Medicine)2022 ‑ 2023

CONTENTS
PHILOSOPHY AND GOAL IN EDUCATION・ ・・・・・・・・・・・・・・・・・・・・・
Living Up to Society’s Expectations
SOMEYA Toshiyuki Dean, School of Medicine, Niigata University・ ・・・・・・・・

1
2

Fostering Leaders in Advanced Biosciences and Highly
Specialized Medical Personnel to Move Advanced Medicine
Forward

3
4
5
6
8
26
28
30
33

NAKAMURA Kazutoshi Director, Graduate School of Medical and Dental Sciences, Niigata University・

ORGANIZATION・ ・・・・・・・・・・・・・・・・・・・・・・・・・・・・・・・・・・・・・・・・・・・・・・・・・・・・
THE SIX-YEAR MEDICAL PROGRAM・・・・・・・・・・・・・・・・・・・・・・・・・・・・・・・
HISTORY・ ・・・・・・・・・・・・・・・・・・・・・・・・・・・・・・・・・・・・・・・・・・・・・・・・・・・・・・・・・・・・・・

FIELD INTRODUCTION・ ・・・・・・・・・・・・・・・・・・・・・・・・・・・・・・・・・・・・・・・・・・・・
INTERNATIONAL EXCHANGE・・・・・・・・・・・・・・・・・・・・・・・・・・・・・・・・・・・
PROJECTS・ ・・・・・・・・・・・・・・・・・・・・・・・・・・・・・・・・・・・・・・・・・・・・・・・・・・・・・・・・・
DATA・・・・・・・・・・・・・・・・・・・・・・・・・・・・・・・・・・・・・・・・・・・・・・・・・・・・・・・・・・・・・・・・
BUILDING LAYOUT・ ・・・・・・・・・・・・・・・・・・・・・・・・・・・・・・・・・・・・・・・・・・・・・・

PHILOSOPHY AND GOAL IN EDUCATION

Philosophy

Contribute to human well-being through medical
science

Goal

Develop human resources that
1. contribute holistic medical care with rich humanity and high ethicalnature2. contribute as a leader of highly specialized medical teams
3. contribute as medical researchers and educators with a wide
perspective and great interest in learning
4. contribute to health, medical care, social well-being and welfare
administration
5. contribute to local health care and global medical activities
6. maintain inquiring minds, research minds, self-learning attitudes
continuously
Contents and Features in Education
The Medical Program in the School of Medicine educates future medical practitioners
and researchers who will be involved in fields related to medical science. In addition toproviding students with sufficient knowledge, we also help them become doctors withrich humanity and high ethical nature, and we implement the following professional
education in order to contribute to human well-beings through medicine:⃝an integrated educational program from fundamental to clinical medicine inaccordance with international standards⃝the introduction of active learning in the curriculum for all students⃝a medical research practicum to experience cutting-edge medical research⃝participation-style training (clinical clerkship) for diagnosis and treatment wherestudents learn from primary care to highly advanced medical technology by joining
medical teams at the Niigata University Medical and Dental Hospital and the affiliatedhospitals⃝an international exchange program to foster international sense (English conversation,short periods of study abroad, etc.)

We Expect Our Students to⃝be strongly interested in study and scientific research in order tobecome good medical practitioners and researchers⃝have good educations and kind hearts and act in harmony withothers⃝think broadmindedly and have positive attitudes

1

MESSAGE
Living Up to Society’s
Expectations
SOMEYA Toshiyuki
Dean
School of Medicine, Niigata University
Our medical program has been pursuing medical education andresearch for more than a hundred years since our foundation.
Our history can be traced back to 1910, when National Niigata
Medical College was founded. In 1922 we became National Niigata
Medical University, which was the sixth national university
school of medicine; in 1949 we became Niigata University Schoolof Medicine as we are known today. In 2020, we celebrated the110th anniversary of our founding. Our school has more than
10,000 alumni; many of them are doctors and researchers involved
in medical science at the international level. Taking pride in our
traditions, we must steadily work to continue to create history.
--A new approach for the School of Medicine-Niigata University School of Medicine has been implementingchanges within the School such as systematically improving
the undergraduate and graduate schools, acquiring personnel,
obtaining the certificate for the assessment of medical educationin accordance with international standards, designing a new
curriculum and furthering international exchange programs.
Nevertheless, the environment for all the universities in Japan is
becoming more and more challenging so as to make this work
seem insufficient.
We must take this difficult situation, in which universities
are now placed, as an opportunity for new development, anddiscover a new image of a school of medicine that meets societal
expectations. We should use the potential of a medical school toelevate medical standards and innovate here in Niigata. Obtaining
financial support from society at large is also necessary. Therefore,bilateral cooperation between the Faculty of Medicine and the
Medical and Dental Hospital becomes increasingly important. For
our School of Medicine to develop into the next age, we must
face and address such numerous problems day by day, working tosolve them and improve our program.
--To foster young power for the future-Under the educational philosophy of contributing to humanwell-being through medical science, our School of Medicine has
been educating young medical practitioners and researchers.
We have established an environment where we can educate
students having sufficient knowledge, inquiring minds, educationand humanity to become medical professionals who can pursue
all medical areas of expertise: clinical areas, medical research andmedical administration. The following are our six educational goals:
We develop professionals who
1. contribute holistic medical care with rich humanity and highethical nature.
2. contribute as a leader of highly specialized medical teams.
3. contribute as medical researchers and educators with a wide
perspective and great interest in learning.
4. contribute to health, medical care, social well-being andwelfare administration.
5. contribute to local health care and global medical activities.
6. maintain inquiring minds, research minds, self-learning
attitudes continuously.
The Faculty of Medicine, School of Medicine contributes to2

the improvement of regional medicine, health, and welfare byfocusing not only on clinical medicine but also on preventive
medicine, while collaborating with social resources such as medical
institutions, medical associations, and administrative agencies in
the local community. Based on our experience with disasters andnew coronavirus infections, we are also working to train doctors
who have the comprehensive medical skills that are essential forsociety in the future as well as doctors with social medical skills
who understand the imbalance between insurance and medical
needs and resources in each region and work to solve themthrough multidisciplinary collaboration including the government.
In addition, we are expanding our activities overseas. We areconducting exchanges in medical science and medical care with
Europe, the United States, countries around the Sea of Japan rim
and other Asian countries. International Student Week, exchange
among medical students, is held in summer by student volunteers
as well as providing opportunities for medical research training
and clinical training for students in Europe, the United States, andAsia.
We hope the students studying at the Faculty of Medicine
in the Niigata University School of Medicine will learn cuttingedge advanced medical care and community medicine in thisblessed environment of Niigata, set high ambitions with a global
perspective, work hard together and aim to be professionals who
can contribute to society through medical science and medical
care.
--Gazing into the future of medicine-Niigata University also has the Graduate School of Medical and
Dental Sciences, enabling our alumni and others to continue theirstudies and research.
In research, we have achieved promising results in many areas,
including studies in cerebral nerves, kidneys, cancer, circulatoryorgans, digestive organs, cytobiology and infectious diseases andso on. Our research and results are internationally well-known
and respected. Some of our achievements are introduced on thewebsite of Niigata University School of Medicine.
We encourage students to study at the Graduate School of
Medical and Dental Sciences after finishing the School of Medicine.
Through research we can learn much that is helpful when we
work as clinicians.
--Mission and community-The mission of a university naturally includes education,
research and contribution to society. Niigata University School of
Medicine emphasizes medical practice rooted in Niigata, fostering
the ability to work and learn in the world, and expanding into theglobal community.
In the midst of the current times where competition andevaluation predominate, we describe a picture of the future to
realize our wishes. We face difficult conditions, but we hope ourstudents will devote themselves to their studies and research withpride, determined to search for a way to a hopeful future. We
sincerely hope Niigata University School of Medicine enjoys theconfidence and love of the people in our community.

Fostering Leaders in Advanced Biosciencesand Highly Specialized Medical Personnel
to Move Advanced Medicine Forward
NAKAMURA Kazutoshi
Director
Graduate School of Medical and Dental Sciences, Niigata University
Niigata University’s Graduate School of Medical and Dental Sciences has integrated medical
and dental departments, which has eliminated the walls between conventional medical and dental
departments and courses. Education and research respond to environmental changes that surroundmedical and health care. The school focuses on educating highly specialized medical personnel
such as researchers who will focus on advanced bioscience research in the 21st century, doctors
and dentists who will provide advanced medical care due to this research, and public healthpractitioners who will provide preventive medicine in the community and international society.
The Graduate School of Medicine consists of three departments, and provides education andresearch guidance for graduate students under the following features and educational philosophy:
1. Molecular and Cellular Medicine Program: Researches and analyzes diseases using molecular
cellular biology. Develops preventive methods and treatments for diseases. We foster advanced
bioscience researchers and highly specialized medical personnel involved in molecular cell medicine.
2. Bio-functional Regulation Medicine Program: Comprehends the living body syntheticallyfrom the perspective of the organs. Researches and analyzes biological functions and pathologicalconditions. Develops preventive methods and treatments for diseases. We foster advanced
bioscience researchers and highly specialized medical personnel involved in bioregulatory medicine.
3. Regional Disease Control Medicine Program: Researches and analyzes diseases in relation
to society, time and space. Develops prevention and control methods for regional diseases
corresponding to the low-birthrates, aging society and information society. We foster advanced
bioscience researchers and highly specialized medical personnel involved in community disease
control.
Distinctive research areas of our medical research school include neurology and brain research,kidney research, big data and artificial intelligence (AI), and global health With regard to neuro/brain
research, many basic and clinical courses in a wide range from basic research in neuroscience todisease are conducted in collaboration with the Brain Research Institute, the only national university
corporation affiliated with Niigata University. Regarding kidney research, Kidney Research Center
affiliated with the Graduate School (Basic research division: Molecular Kidney Pathology; Clinicalresearch divisions: Kidney and Collagen Disease Medicine; Pediatric Research, Kidney and Urology;
Collaborative research divisions: Functional Molecular Medicine, Pathological Nutrition, Biofluid
Biomarker Center) is conducting basic and clinical research on kidney disease. In addition, big data
research aimed at the prevention and treatment of chronic diseases is being conducted mainly
through the Medical AI Center, and international healthcare research aimed at combating infectious
diseases around the world is also being vigorously pursued.
As part of our international exchange and contribution, we welcome international students
from many countries. Among those countries, Niigata University has been promoting medical
exchange with Russia for more than 20 years due to our geographical closeness. We both welcome
international students and send our students abroad through double degree programs and shortterm study abroad programs with Russian medical universities.
We are working to foster many leaders to spearhead advanced biosciences and highly specialized
medical personnel who will contribute to the local and international communities based on the
education and research at our graduate school.

3

ORGANIZATIONOur university has the Education and Research Institute. All faculty in charge of theundergraduate and graduate schools are members of the Institute, which dispatches faculty
to the undergraduate and graduate schools to teach and research.

Education andResearch
Medical anddental courses

School of Medicine

Dispatchfacultymembers

Graduate School of Medical
and Dental Sciences(Master’s Program andDoctoral Program)

School of Medicine Courses
Field

AnatomyRepresentative teacher
Professor

SATO Noboru

Ophthalmology

Representative teacher
Professor

FUKUCHI Takeo

Neurobiology and Anatomy Professor TAKEBAYASHI Hirohide

Otolaryngology - Head and Neck Surgery Professor HORII Arata

Neurophysiology

Obstetrics and Gynecology Professor YOSHIHARA Kosuke

Microscopic Anatomy Professor SHIBATA Shinsuke
Developmental Physiology

Omics and Systems Biology
Neurochemistry and Molecular Cell Biology
Pharmacology

Molecular Pathology
Bacteriology
Virology

Preventive Medicine

Professor
Professor
Professor
Professor
Professor
Professor
Professor
Professor
Professor

International HealthProfessor

Immunology and Medical Zoology

Professor

Forensic Medicine

Professor

HASEGAWA Isao

SUGIYAMA Sayaka
MATSUMOTO Masaki

IGARASHI Michihiro

HIRASHIMA Masanori
KONDO Eisaku
MATSUMOTO Sokichi

FUJII Masahiro
NAKAMURA Kazutoshi

SAITO Reiko

KATAKAI Tomoya

TAKATSUKA Hisakazu

Cellular Physiology

Professor

KANKI Tomotake

Cardiovascular Medicine

Professor

INOMATA Takayuki

Hematology, Endocrinology and Metabolism Professor SONE Hirohito
Respiratory Medicine and Infectious Diseases Professor KIKUCHI Toshiaki

Gastroenterology and Hepatology
Psychiatry
Pediatrics

Digestive and General Surgery

Professor
Professor
Professor
Professor

TERAI Shuji

SOMEYA Toshiyuki

SAITOH Akihiko
WAKAI Toshifumi

Thoracic and Cardiovascular Surgery Professor TSUCHIDA Masanori

Orthopedic Surgery and Rehabilitation Professor KAWASHIMA Hiroyuki
Plastic, Reconstructive and Aesthetic Surgery

Professor

Pediatric Surgery

Professor

Dermatology
Urology
4

Field

Professor
Professor

MATSUDA Ken

KINOSHITA Yoshiaki
ABE Riichiro

TOMITA YoshihikoRadiology and Radiation Oncology Professor ISHIKAWA Hiroyuki
Anesthesiology

Emergency and Critical Care Medicine
Medical Oncology

Clinical Pathology

Professor
Professor
Professor
Professor

BABA Hiroshi
NISHIYAMA Kei
SAIJO Yasuo

AJIOKA Yoichi

Neurosurgery（Brain Research Institute） Professor FUJII Yukihiko

Neurology（Brain Research Institute） Professor ONODERA Osamu

Cell Biology（Kidney Research Center） Professor KAWACHI Hiroshi
Clinical Nephrology and Rheumatology Professor（Kidney Research Center）

NARITA Ichiei

Bioinformatics(Medical AI Center) Professor OKUDA Shujiro
Medical Education Center

Professor

SOMEYA Toshiyuki

Disaster Medical Education Center

Specially
Appointed Prof.

TAKAHASHI Masashi

Myanmar Infectious Disease Research Center Professor SAITO Reiko

Histopathology Core Facility Professor AJIOKA Yoichi
Niigata Regional Medical Support Center Medical Branch OfficeSpecially Appointed
Assistant Professor

Cause of Death Education Center

Professor

Center for Research Promotion
General Medicine

Professor
Specially
Appointed Prof.

MIZUSAWA Takeshi

TAKATSUKA Hisakazu
SOMEYA Toshiyuki
KAMIMURA Kenya

Administration Office
Academic Planning Section
General Affairs Section
Accounting Section
Student Affairs Section
Entrance Examination and Clinical and Practicum Section

THE SIX-YEAR MEDICALPROGRAM
Contribute to human well-being through medical science
Graduation examination

6th

Clinical Medicine Lectures (intensive course)
Clinical Clerkship Ⅱ（Participatory Clinical Clerkship）

5th

Symptomatology
Clinical ClerkshipⅠ（Patient-Focused Clinical Clerkship）

4th

3rd
2nd

1st

Introduction to bedside learning(Basic Clinical Skills)
Organ System-Based
Integrated Medicine Course

Medical English Ⅱ

the National Examination
for Medical Practitioners

Post Clinical ClerkshipObjective Structured
Clinical Examination (ＯＳＣＥ)
Computer-based testing (CBT) /Objective Structured
Clinical Examination (OSCE)

Social Medicine: lectures and practiceMedical Research PracticeIntegrated Clinical Medicine Course
Integrated Medical Science(Multi-disciplinary Cooperative Education)(Medical Professionalism)(Behavioral Science)

Basic Medicine: lectures and practiceSocial Medicine: lectures and practiceMedical EnglishⅠ

Early Medical Exposure
Introduction to Medical Art
Journal Club

Liberal Arts

Introduction to Medicine

Medical Education Program of Niigata University was
accredited by the Japan Accreditation Council for Medical
Education (JACME) in 2013. At the beginning, JACME wasconsisted of Six Medical Universities , Niigata University,
Tokyo Medical and Dental University, the University of Tokyo,
Chiba University, Tokyo-Jikeikai Medical University, and Tokyo
Women’s Medical University. The accreditation was supported
partly by the Grant of Ministry of Education, Culture, Sports,
Science and Technology, Japan. JACME was certificated to be
the agency to perform accreditation of Medical Education by
the World Federation of Medical Education (WFME) on March
2016 and the Medical Education Program of Niigata University
School of Medicine was accredited to satisfy the standards for
Basic Medical Education by JACME on April 2017.
At the accreditation, expertise of JACME suggested following
eight issues to be solved:(1)Introduction of outcome-based medicine.
(2)Cooperation between faculty of preparatory education andfaculty of medical education.
(3)Harvesting competency of medical research for students.
(4)Vertical integration of basic and clinical medicine.
(5)Introduction of behavioral science and interprofessional
education.
(6)Introduction of more than two years of clinical clerkshipwhere students join professional team and round core
disciplines of medicine, surgery, pediatrics, OB-GYN, psychiatry,and general practice/family medicine.
(7)Introduction of the post-clinical clerkship OSCE (Post-CC OSCE).
(8)Introduction of formative assessment of clinical clerkshipsuch as port-folio, etc.
We started new curriculum since 2014. Specific changes of
the new curriculum we made according to the suggestions are

as follows:(1)Based on outcome-based medicine, faculties of preparatory
course and medical course communicate more frequently
than before. At the same time, students can choose German,
French, Russian, Chinese, Italian, Spanish and Korean as second
language. We also start “Introduction to Medical Science”
for the Year 1 students to enhance students’ motivation for
medicine.
(2)In order to harvest competency of medical research forstudents, we moved “Medical Research Practice” from Year 4
to Year 3 to provide students with longer research time until
graduation.
(3)Vertical integration of basic and clinical medicine forYear 2 students with active learning such as problem-basedlearning(PBL) and team-based learning(TBL).
Students learn behaviroral science and Interprofessional
medicine by active learning.
(4)The clinical clerkship is performed between January of Year 4
and July of Year6. The entire training period has been extended
from 52 to 66 weeks. Year 5 students round core disciplines
of medicine, surgery, pediatrics, OB-GYN, and psychiatry three
weeks, respectively. Students join as member of professionalteam, communicate and investigate patients, check data ofpatients, and attend conference to discuss patient diagnosis
and treatment. Students write electrical records of the patientsand electrical port-folio everyday. Students are accessed byfaculty formatively and summatively during clinical clerkship.
(5)Implementation of post-clinical clerkship OSCE trial in 2016
and common achievement test organization(CATO) Post-CC
OSCE trial in 2017. Students are mandatory to pass Post-CC
OSCE at graduation since 2017.
Medical education of Niigata University will be accredited
again until March 2022.
5

HISTORY

Before National Niigata Medical College

1869
1870
1873
1876
1879
1883
1888

1910

A pharmaceutical institution (Shiran Pharmaceuticals) and a vaccination center (Niigata
Prefecture Medical Office) were established on the grounds of Shofuku-ji Temple
located in Gono-cho (present Nishibori-dori 7), Tera-machi, Niigata City (May 12)
Niigata Temporary Hospital (Kyoritsu Hospital) established
Opened Niigata Hospital at Yoko-sanban-cho, Niigata
Control of Niigata Hospital transferred to Niigata Prefecture and renamed Niigata
Prefectural Hospital Medical School
Niigata Prefectural Hospital Medical School changed its name to Niigata Prefectural
Medical School (B-type Medical School)
Renamed Prefectural A-type Niigata Medical School
Abolished Prefectural A-type Niigata Medical School

National Niigata Medical College established(April 6)
The college received 728 applications by the endof May, which was the application deadline. The
inaugural class of 70 students was admitted after
the entrance examination.

Graduation album of 1915

Niigata Medical College from the 1914 graduation album

6

1915

Dr. Hideyo Noguchi visited our school and lectured(October)

1922

National Niigata Medical College became the National
Niigata Medical University

1923

Niigata Medical University Relief Team formed after theGreat Kanto Earthquake and the team visited Tokyo toprovide relief

1939

The four-year Temporary Medical Specialty Department
affiliated with Niigata Medical University was establishedin accordance with Royal Decree No. 315

1944

Renamed as an affiliated Medical Specialty College on
March 31 in accordance with Royal Decree No. 200

1947

Emperor Showa (Hirohito) visited our university(Professor Tatsuji Ito and Professor Yasuichi Ito lectured
about scrub typhus and Professor Mizuho Nakada aboutbrain tumors)

1949

Niigata University (Faculty of Humanities, Education,
Science, Medicine, Engineering and Agriculture) wasestablished in accordance with the proclamation of
the National School Establishment Act (Law No. 150 of1949)

Doctors

A lecture by Dr. Hideyo
Noguchi from the 1916
graduation album

Nippori Nagaku-yama Hongyo-ji Temple fromthe 1924 graduation album

Emperor’s visit from the 1950 graduation
album

1955

The first 98 students graduated from Niigata University

1956

Outpatient building (4-story reinforced concrete) of

1960

The 50th anniversary of Niigata University School of
Medicine

1967
1973

Niigata University Brain Laboratory established (April)

1982

The current affiliated Asahi-machi library branchcompleted1985

The 75th anniversary of Niigata University School of
Medicine
The Yujin Memorial Hall completed as part of the 75th
anniversary commemoration project

1999

Department of Health Sciences of Medical School
established (October)

2001

Graduate School of Medical and Dental Sciences
established (April)

2003

Niigata University Medical and Dental Hospitalestablished (October 1)

2004

Became the Niigata University, National University
Corporation in line with National Corporation Law

2005

New building of Medical and Dental Hospital completed(August)2010

The 100th anniversary of Niigata University School of
Medicine2012

Outpatient building ofMedical and Dental
Hospital completed(April)2014

Redevelopment
project of Medical
and Dental Hospitalcompleted (June)

School of Medicine (March)

affiliated hospital was completed

Graduation photo from the 1955 graduation
album

Affiliated Kidney Research Center and affiliated Animal
Laboratory Facility of Niigata University School of
Medicine established (April)

Affiliated hospital from the 1956 graduation album

Yujin Memorial Hall from the 1990
graduation album

7

FIELDINTRODUCTION

AnatomyProfessor SATO Noboru

We have active research programs with area ofmorphogenesis and provide education programs inhuman gross anatomy through osteology and dissections.
We are researching morphogenesis from the embryologicalperspective. Neurons go through a series of processes suchas production, migration, differentiation, and cell death toform initial neural circuits. We are studying this phenomenonincentralandperipheral

nerves.

We

alsoconduct

comparative anatomical analysis of the musculoskeletal
formation of the trunk and limbs and study the evolutionof vertebrates. Using experimental model animals such as
genetically modified mice, birds, and small fish, we study
making full use of morphological research methods as wellas advanced molecular biological methods. In terms ofeducation, we handle general anatomy and gross anatomy,
and we conduct osteology and human anatomy training.
We also handle the work related to body donation, whichis indispensable for this education. We cooperate with the
Niigata White Chrysanthemum Association, a philanthropist
group, to receive dissected bodies from the Niigata University
School of Medicine and Dentistry and on related events. We
interact with the general public, such as medical students,
philanthropists,

andtheir families, throughanatomy education.

Neurobiology and Anatomy

Professor TAKEBAYASHI Hirohide

We are investigating the developmental mechanism of thenervous system and the pathophysiology of intractableneurological diseases. We are also trying to develop
treatment methods for the neurological diseases.
The nervous system develops under the influence ofboth genetics and the environment. One of our goals
is to elucidate the mechanism of development of thiscomplex and sophisticated nervous system. In thedeveloping brain, neural stem cells give rise to neurons
and subsequently glial cells. These cells form neuralcircuits while migrating and differentiating. After birth,the brain develops, receiving information from thesensory organs. In the nervous system, many intractableneurological diseases are caused by abnormalities inneurons and glial cells. We promote research on the8pathogenesis of these intractable neurological diseases
and

the

developmental

mechanisms

of

the

nervoussystem, fully using experimental methods at the molecular,
cellular, and individual levels. The knowledge obtained inneurodevelopment can be applied to regenerative medicine,
and we are also focusing on developing treatment methods
for intractable neurological diseases. International students
also enroll. We are committed to creating a research
environment where lab
members can learn andprogress daily. Medical
school education also
includes embryology
and neuroanatomy.

Microscopic Anatomy

imaging with much higher resolution than light, transmission
electron microscopes can observe the fine internal structure

Professor SHIBATA Shinsukeof samples such as cells and tissues, and scanning electron
microscopes can observe the fine surface morphology

We are trying to reveal the detailed structure andfunction of the cells and the tissues by using various
kinds of cutting-edge microscopic technology,
including electron microscope and light microscope.

of samples. Combining molecular biological approaches
using light microscopy with very high-resolution imaging
techniques using transmission electron microscopy and

We are researching to visualize the structure andscanning electron microscopy provides a comprehensivefunction of biological samples by imaging them inunderstanding of cells and tissues as well as providing

our laboratory. We use microscopes for observation

possibilities to apply to structural analyses in a wide range ofand develop sample preparation methods for optimal

fields. We are conducting numerous joint research projects

imaging in our research. Optical microscopes, including

with researchers around the world by applying these cutting-stereomicroscopes, fluorescence microscopes, andedge imaging

super-resolution microscopes beyond the resolution

technologies.

limits of light, are used to visualize specific moleculesalong with general histological structural analysis.
Amongelectronmicroscopes

that

use

electron

Neurophysiology

Developmental Physiology

We aim at clarifying physiological mechanisms
by which the cerebral network produces
intelligence.

We decipher the mechanism by which children's brains
grow flexibly from the functional analysis of genes andneural networks.

Where does our intelligence come from? We

The brain is one of the most incomprehensible organs foraim at clarifying the physiological mechanisms

humans even though it is part of the human body. How doof the global brain network creating humanpeople see the scenery, how do they feel likes and dislikes,

intellectual abilities such as visual imagery,how do they remember, and how do they develop their

linguistic comprehension, and social interactions.

individuality? All the answers are in your brain.

Professor HASEGAWA Isao

To achieve this goal, we generate scientificallyverifiablehypotheses

on

the

Professor SUGIYAMA Sayaka

Can babies see and feel? When asked, many students

higher-orderanswered that they were the same as adults. In fact, the baby's

brain functions with unique primate/rodent

brain is immature; brain growth is greatly influenced by the

animal-model paradigms, and empirically test

surrounding environment and experiences. The experience ofthe hypotheses by physiological recording

listening and speaking is necessary for mastering your nativeof the global brain network activity with alanguage, and the experience of seeing is also important for

millisecond time resolution. To capture theimproving your eyesight. The time when the neural network

brain-wide neural activity, we have specificallyof the brain grows significantly by absorbing experiences isdeveloped a flexible mesh electrocorticographic

called the critical period. There are many unknowns in the(ECoG) electrode array and minimally-invasive

mechanism of the critical period. In our laboratory, we analyze

surgical procedures to gently place it on thethe genes necessary for the critical period and the function ofbrain surface. Researches of heterogeneous

the neural network created during the critical period by fully

backgrounds such as animal neurophysiology,

using molecular biology, histology, and physiology, and clarify

engineering, and clinical medicine work together

the growth mechanisms of vision and emotion.

to promote interdisciplinary medical-engineeringcollaborating projects.

Recently, there has been talk about an increase in mental
disorders such as autism. Miswiring of neural networks as thebrain develops predisposes us
to mental illnesses. If we canunderstandthemechanismof flexible wiring of neuralnetworks,

ourresearchis

expected to be useful in thetreatment of brain diseases.
9Omics and Systems Biology

proteomics, including iMPAQT, our original platform forprotein absolute quantiﬁcation. Using these technologies,

Professor MATSUMOTO Masaki

we are researching basic medical issues such as cancer

We are working to understand the operating
principles of life systems through exhaustive
protein analysis.

backgrounds; by cooperating, we are rising to the challenge

Proteins are important functional elements involved
in all biological phenomena. Our laboratory has
developed techniques for comprehensively andquantitatively measuring protein expression levels,and aging. Our laboratory gathers researchers with diverseof new life science
research that could
not be achievedby conventional
methods.

post-translational modifications, and protein-protein
interactions, and has applied them to researchon diseases such as cancer. We have developed
technologies related to high-throughput and functional

Neurochemistry and Molecular
Cell Biology
Professor IGARASHI Michihiro
We are tracking the molecular mechanisms involved in nerve
growth and axon regeneration, by utilizing new technologies.
We are investigating the molecular basis that supports thefunction of growth cones (structures with high motility formedat the tips of the projections of developing neurons), which
are essential structures for nerve growth and regeneration,
and we have clarified the following:1) We are investigating the characteristics the major
molecular constituents in the growth cone.
2) Using a super-resolution microscope (a fluorescencemicroscope that can analyze the behavior of molecules thatcannot be seen with a normal microscope), we demonstrated
that there is new movement linked to the membrane and thecytoskeleton in the most mobile part of the growth cone.
3) Using a new technology called phosphoproteomics,
we demonstrated that there are specific phosphorylation(modification) sites of proteins in growth cones, and thatspecific antibodies against new phosphorylation sites canserve as molecular markers for nerve growth and regeneration.
4) We discovered that a special membrane structure calleda lipid raft is involved in the
projection formation (polarity
formation) of neurons, and thatthe molecular groups necessary
for polarity formation gather here
all at once, resulting in speedy
formation.
We are currently analyzing therole of these phosphorylation in
nerve growth, the significance oflipid synthesis, and the role oforganelles.
10

Pharmacology

Professor HIRASHIMA Masanori

We are studying molecular mechanisms
underlying the formation and maintenanceof the vascular system.
The vascular system comprises blood vessels
and lymphatic vessels, which efficiently transport
cells and substances to serve as a lifeline
throughout the body. Blood vessels are known
to be essential for sustaining life, but much is
unknown about lymphatic vessels. Therefore,
their role in the onset and progression of
diseases such as lymphedema (swelling),
Alzheimer's disease, and glaucoma is expected
to be elucidated. In our laboratory, we are
studying molecular mechanisms of lymphatic
vascular development, using transgenic mice
generated by CRISPR/Cas9 genome editing.
We are also studying the relationship between
abnormal embryonic vascular development
and the risk of developing diseases laterin life, and the blood vessels and lymphatic
vessels associated with tumors. These studies
are conducted in collaboration with experts invarious fields both on and off campus.

Molecular Pathology

Bacteriology

We promote the comprehensive pathology for the
future medicine with two pillars: Advanced Molecular
Tumor Pathology; innovative research for Novel
Diagnostic and Therapeutic Technology.

Analysis of pathogenicity and longevity of tubercle
bacillus, mycobacteriosis treatment, diagnostic
methods and vaccine development.

Professor KONDO Eisaku

The course specializes in tumor pathology, and thebasic pathology field promotes research to elucidate thekey molecular mechanisms of invasion and metastasisof malignant tumors, mainly focusing on intractable
cancers,forclinicaldiagnosis

andapplication.

Remembering that elucidating the mechanisms of tumor
resistance against advanced drugs is also an important
issue, we have created a practical pathological researchsystem that integrates molecular and histopathologicalanalyses. Our goal is to find clues for overcoming
cancer that can be applied to clinical practice. With theaim of applying the research to cancer therapeutics, allmembers are working together to implement a variety
of approaches, such as non-invasive cancer imaging/therapy technology using tumor-homing peptides as
an innovative medical technology for next generation
tumor medicine. We believe this research is quite
unique in pathological department. Our department
aims advanced and comprehensive tumor pathology
through crosstalk with the forefront of cancer medicine
in the 21st century.

Professor MATSUMOTO Sokichi

COVID-19 has caused serious damage. However,
one infectious disease causes the same amount ofdamage every year and has claimed the lives of one
billion people, the highest number ever: tuberculosis. In
contrast to the eradication of diseases such as smallpox
that rivaled tuberculosis, once tuberculosis breaks out,
no country is able to eradicate it. A certain number ofpatients always occur (10 million cases annually) withasymptomatic infections among two billion humans. We
are researching, believing that vaccination preventing theonset of tuberculosis and discovering a drug to kill thedormant bacteria that infect humans widely will control
tuberculosis. Nontuberculous mycobacterial infection(NTM), which resembles tuberculosis, is intractable andhas recently been assumed to be an intractable disease.
We are also researching countermeasures against NTM.
We are trying to find out the secret of longevity common
to living things from the longevity of mycobacteria. Our
department has a BSL3 laboratory and is characterized
by being able to carry out genetic recombination of
Mycobacterium tuberculosis, an experiment approvedby the Minister of Education, Culture, Sports, Scienceand Technology within the classroom. Using cuttingedge tools, we approach the biological phenomena ofbacteria, andbased on that,weresearch

tosuppress

intractablediseases.

Virology

formation of pathogenic protein aggregates in AD, PD, and
ALS. We are analyzing the pathology of AD and ALS using AD
Professor FUJII Masahiro

and ALS model mice and USP10 knockout mice. We are also

We elucidate the pathogenic mechanism ofneurodegenerative diseases and leukemia causedby viruses and develop therapeutic medication.

diseases, we are working to elucidate the pathogenesis of

We aim to elucidate the pathogenesis of viral andnon-viral neurodegenerative diseases and develop
therapeutic agents for them. As for non-viral diseases,
we are working to elucidate the pathogenesis of
Alzheimer's disease (AD), Parkinson's disease (PD), anddeveloping therapeutic agents that target USP10. As for viralneurodegenerative diseases caused by herpes simplex virus,
coxsackievirus, and human T-cell leukemia virus type 1. USP10
is also involved in thepathogenesis of viralneurodegenerative
diseases.

amyotrophic lateral sclerosis (ALS). Pathogenic proteins(tau, α-synuclein, TDP-43) form aggregates that are toxic
to neurons and cause disease in AD, PD, and ALS. We
identified the protein USP10 as a factor that induces the11

Preventive Medicine

Professor NAKAMURA Kazutoshi

We are conducting researches to prevent agerelated diseases such as dementia and osteoporosis
to extend healthy life spans.
Our primary research studies are the Murakami

developing simple predictive urine markers for Alzheimer's
disease by omics analysis: proteomics, metabolomics,
etc. In addition, we are conducting researches on topics
in preventive medicine and public health such as aninternational collaborative research on gallbladder cancer
prevention. For more information, please visit http://www.
med.niigata-u.ac.jp/hyg/index.html.

Cohort Study and dementia omics study. The Murakami
Cohort Study is a long-term longitudinal follow-up of
approximately 14,000 local residents. We are searchingforenvironmental

factors

relatedtoage-relateddiseases, such as dementia and osteoporosis. We also
use preserved biological samples to measure vitamin
D and try to apply it for disease prevention. Dementia
omics research is the world's first research aimed at

International HealthProfessor SAITO Reiko

We are investigating respiratory viruses such as
SARS-CoV-2 and influenza in Japan and Myanmar.
We are developing the "Research on Influenza-like
Diseases and Pediatric Meningoencephalitis in Myanmar,"
was funded by the AMED Emerging and Re-emerging

Professor KATAKAI Tomoya

Immune response in immune organs such as lymph
nodes, immune cell function and motility, andmolecular mechanism of stromal cells and tissue
microenvironment formation.

Infectious Diseases Research Platform Creation Project,

The immune system is an essential physiologicalwhich is the only overseas research base of Niigata

system for protecting our bodies from pathogens andUniversity. By using a next-generation sequencing,foreign substances and preserving our lives. However,

we analyze the whole genome of SARS-CoV-2 andother than infectious diseases, it is deeply related toinvestigate what kind of variants are prevalent in Japandiseases such as allergies, autoimmune diseases andand Myanmar. We found that COVID-19 vaccination

cancer. In this laboratory, we research the interaction

can prevent the rate of infection and aggravation after

between immune cells and stromal cells in the tissue

collecting the data in Niigata Prefecture. To know

microenvironment with centering on the structure

the extent of the COVID-19 epidemic, we evaluatedand function of immune organs such as lymph nodes,

the effective reproductive number, and applied it for

which are necessary for the acquired immune system

infectious disease control in Niigata Prefecture andthat is responsible for the immunological memory to

Myanmar. We are also investigating an antibody titerwork efficiently. Particularly using the latest imaging

for COVID-19 in medical workers and in facilities fortechniques, we are pursuing the relation between thethe elderly. Regarding influenza, we are investigating

migration or localization of immune cells and the tissue

with the cooperation of clinicians nationwide about theenvironment, focusing on the dynamic behavior of theprevalence of influenza virus, drug-resistant viruses, andimmune system.

also antibody titers after influenza vaccination. We arealso collecting specimens from all over the country for
respiratory syncytial virus, which causes common cold in
infants, and analyzing virus genes to find out what kindof respiratory syncytial virus is prevalent in each region.

12

Immunology and Medical
ZoologyForensic Medicine

Cellular Physiology

We are working together with the Center for Causeof Death Investigation on practice and research ina wide range of fields related to forensic medicine.

We study mitophagy, a selective degradation of

In forensic medicine, we research in a widea majority of the ATP required for cellular activities,

Professor TAKATSUKA Hisakazu

range of fields deeply related to forensic medicine,“Information Learned from Studying the Dead Could
Be Used Help the Living” (Thomas A. Gonzales) in
autopsy

imaging(AI),

pathologicaldiagnostics,

dentistry, toxicology, isotope studies, biochemistry
and abuse. Also, together with the Center for Causeof Death Investigation (https://ccdi.med.niigata-u.
ac.jp/), which was established in July 2017, weare fostering highly specialized professionals in
forensic medicine and those who will lead the next
generation as we work to form the “Base for forensic
medicine and for education and research related
to the investigation of cause of death,” which is a
project operated by a national university operating
expense grant at seven universities nationwide
including Niigata University.

Professor KANKI Tomotake

mitochondria by autophagy.
Mitochondria are important organelles that produce
and their quantity and quality need to be properly
controlled. It is believed that mitochondrial autophagy(mitophagy), a selective degradation of mitochondria
by autophagy, degrades excess or dysfunctional
mitochondria to maintain mitochondrial homeostasis. In
recent years, mitophagy defects have been implicatedin neurodegenerative diseases, and thus mitophagy is
attracting a lot of attention. The aim of our study is
to elucidate the detailed molecular mechanisms andphysiological roles of mitophagy. We have developed
systems to induce and detect mitophagy in multiple
models such as mammalian cultured cells, mice andyeast. We are currently identifying factors involved in
mitophagy, exploring their molecular functions andanalyzing the phenotypes of mitophagy-deficient cells.

left ventricular reverse remodeling, myocardial pathological

Cardiovascular
Medicine

analysis and prediction of left ventricular reverse remodelingusing AI, and research on the frequency and course of heart

Professor INOMATA Takayuki

Targeting cardiovascular diseases, we are building
new treatment systems based on accumulated
clinical data that we will use for research.

failure in cancer patients. We are conducting diverse researchin cooperation with related hospitals in the prefecture. For
details, please visit the Cardiovascular Medicine website(http://www.med.niigata-u.ac.jp/car/).

Ischemia: observation of vascular lesions using
an angioscope and development of diagnostic andtreatment methods for unstable plaque using nearinfraredautofluorescenceimaging.

Arrhythmia:

elucidation of J-waves, atrial and ventricular arrhythmias,
elucidation of the effects of SGLT2 inhibitors on cardiac
rhythm, examination of a new mapping method in
atrial fibrillation ablation, and research on arrhythmia
related to mitochondrial M2 antibody. Heart failure:research on the relationship between alternans and13

Hematology, Endocrinology
and Metabolism
Professor SONE Hirohito

and metabolic diseases, we have secured a large amountof scientific evidence useful for on-site treatment andprevention for both lifestyle therapy and pharmacotherapy
through big data analysis. Along with basic research
aimed at elucidating the pathology in both fields, we are

We are researching in a wide range of fields
from lifestyle diseases to tumors and from basic
experiments to big data analysis, including nutrition,
food, exercise, examination and AI.

developing tools such as apps through industry-academia

Our department develops prevention, diagnosis, and(biology, science and engineering, informatics, statistics,

treatment methods for hematologic diseases (leukemia

psychology, food science, body mechanics, sociology,

andgovernment, general companies, etc.) to increase the depth

malignantlymphoma),

endocrinediseases(thyroid and adrenal glands) and metabolic diseases

joint research.
Our department widely accepts medical professionals
other than doctors and researchers outside medicine

and quality of research.

(diabetes, obesity, dyslipidemia, and hypertension).
We provide four related endowed courses: “HealthLife Extension and Lifestyle Disease Prevention andTreatment Medicine Course,” "Prevention of Lifestylerelated Diseases and Medical Checkups," "Regional
Medicine and Health Studies," and “Next Generation
ICT Medical Science Course.” With the Niigata
University Health Education Innovation Center, we are
active in industry-government-academia collaboration.
In hematologic diseases, we are involved fromprotocol creation to multicenter joint research. We
are also searching for new prognostic factors basedon data gathered over many years. In endocrine

Respiratory Medicine andInfectious Diseases

Professor KIKUCHI Toshiaki

athlete asthma, and basic research using a mouse modelof bronchial asthma.
The Respiratory Physiology Group conducts clinical research
focusing on sleep apnea syndrome and perioperative

Our department conducts active clinical and basic
research in various respiratory and infectious
diseases.

respiratory management through pulmonary rehabilitation.

Respiratory and infectious diseases are diverse anddiseases and infection control (nosocomial infection control).

divided into five research groups: diffuse lung diseases,

For more information, please visit the Internal Medicine ofrespiratory

tumors,allergic

diseases,

respiratory

physiology and infectious diseases.
The Diffuse Lung Disease Group has a unique focus
on rare diseases such as interstitial pneumonia andpulmonary alveolar proteinosis.
The Respiratory Oncology Group has designed andcarried out a number of independent clinical trials, aswell as conducting basic research
on anti-tumor immunotherapy inmouse models and novel methods
to control cisplatin nephropathy incooperation with the Renal Group.
The Allergic Disease Group is
conducting a survey of asthma
treatment
14

throughout Niigata Prefecture, a survey and research on

and

COPD

patients

In the field of infectious diseases, we are conducting
basic research on iron metabolism, treatment of infectious

Respiratory and Infectious Diseases website (https://www.
med.niigata-u.ac.jp/resp/welcome.html).

Gastroenterology andHepatology

Professor TERAI Shuji

We are developing novel diagnostic and therapeuticmodalities aiming to overcome intractable diseases
and to improve pathophysiological conditions in theupper and lower gastrointestinal tracts, liver, biliary
tract and pancreas.
The mission and vision of our department is to change
the future of people by developing new diagnostic
and therapeutic methods while challenging incurable
diseases and tackling undiagnosed diseases. We aim
to nurture the next generation leaders through thetraining of general gastroenterologists and clinician
scientists as part of human resource development.

of regeneration inducers (physician-initiated clinical trial),
pathologicalanalysisof

non-alcoholicsteatohepatitis

from the viewpoint of organ network and the relationshipbetween digestive diseases and intestinal microbiota,
development of new drug therapy using small fish models,development of gene therapy and gene editing therapy for
intractable diseases, development of local regenerative
medical preparations using bioengineered materials andexosomes for gastrointestinal stenosis and pancreatic juice
leakage, exosome research for gastrointestinal cancers,
elucidation of nutrient absorption mechanism in the small
intestine, and development of new medical equipment using
AI and new materials. We are also working on preemptive
medical care for digestive diseases associated with aging
and lifestyle habits in collaboration with endowed chairs at
three locations within Niigata Prefecture.

As for digestive organs, we are interested in organ
networks, and we are using various approaches todiagnose and develop treatment
methods for homeostasis disruptionof digestion, absorption, and metabolism.
Major research topics include thedevelopment of regenerative therapy
toimprovehepatic

fibrogenesis

and liver regeneration for cirrhosis
using mesenchymal stem cells andexosomes (Phase I/II), development

Psychiatry

Professor SOMEYA Toshiyuki

We research molecular genetics and clinicalpharmacology of mental disorders centering on
schizophrenia and autism spectrum disorders.
We are researching molecular genetics with thegoal of elucidating the molecular pathogenesis of
schizophrenia and autism spectrum disorders andto develop radical treatments based on the results.
Based on the findings obtained in our research, weare comprehensively analyzing the effects of risk geneof Theory of Mind, which is the core symptom of autism
spectrum disorder.
In addition, we are researching individual differences in
responsiveness and side effects to psychotropic drugs, clinicalpharmacology on the relationship between psychotropic
symptoms and sex hormones and inflammatory cytokines
as well as conducting large-scale investigations on perinatal
mental health and pathological research on perinatal
depression.
For details, please visit the website of the Departmentof Psychiatry, Niigata University School of Medicine (http://
www.niigata-dp.org).

mutations on neuronal development (neurite outgrowthand synapse formation) through high-content screening
in collaboration with the Department of
Neurochemistry.
We are also investigating brain activity
in a nonverbal false belief task, working
with humans (magnetoencephalography)
and monkeys (electrocorticogram andneedle electrodes) in collaboration with
the Department of Neurophysiology toelucidate the brain basis of the disorder
15

Pediatrics

Professor SAITOH Akihiko

We are researching the diagnosis, cure, andprevention of childhood diseases to protect the
future for children.
In the Department of Pediatrics, we are vigorously
researching diagnosis, treatment, and prevention ina wide range of fields, including infectious diseases,
blood, tumors, circulatory organs, endocrine secretion,
metabolism, kidneys, collagen, neonatal, and neurologicaldiseases in children.
Our main research areas are the following: Infectious
diseases - focusing on microbial diagnosis of severe
infections, we conduct research on the pathologyof parechovirus-A3 infection which causes severe
infections, especially in newborns and early infants, aswell as the research related to new treatment methods.

Digestive and General Surgery

Thoracic and Cardiovascular Surgery

We strongly promote development researchon comprehensive genomic analysis in solid
tumors using next-generation sequencing.

In the Department of Thoracic Surgery, we are
implementing basic research for the highly specialized
clinical application from children to adults both inGeneral Thoracic Surgery and Cardiovascular Surgery.

Professor WAKAI Toshifumi

Personalized medicine and precision medicine thatfind the optimal treatment through comprehensive
genomic analysis are starting. In our laboratory,
we work with domestic and overseas research
institutions and companies to establish a platform
for optimal treatment based on comprehensive
genomic analysis adapted to Japanese patients. In

order to embody the value of new medical care as
quickly as possible in Japan, we establish an academic
system that combines pharmacogenomics withsurgical oncology based on next-generation
sequencing analysis. We promote the global
activities of young researchers, strategicallybuild an international network, and educate andenhance research and competitiveness as a worldclass interdisciplinary cancer genome analysis
research base. Based on genetic alterations, we
focus on preventive medicine that diagnoses
and predicts diseases that are likely to occur inthe future so that we can then intervene. While
implementing clinical research on both the resultsof pancreas transplantation from brain death
donors and the long-term follow-up results, weare elucidating the engraftment mechanism of islet
cell transplantation and researching to construct
the basis for the development of transplantation
treatment methods for diabetes.

16

Blood and tumors - research for application to pediatric cancer
diseases of CAR (Chimeric Antigen Receptor)-T cell therapy,
which is attracting attention as a new cancer treatment
method. Endocrine secretion and metabolism - researchon genetic diagnosis of unknown endocrine and metabolic
diseases and development of new treatment methods forchildhood Graves’ disease. Circulatory organs - elucidation ofrisk factors for coronary artery lesions in Kawasaki disease
and identification of causative genes for arrhythmia inchildren. Renal and collagen disease - role of macrophages
and urinary megalin in children’s renal disease. Neonatal
area - relationships between premature infants and intestinal
microbiota and innate immunity. Nerves - genetic analysis ofacute encephalopathy andconvulsive disorders.
These studies are importantfor protecting the futureof children and are highly
regarded both in Japan andoverseas.

Professor TSUCHIDA Masanori

In the respiratory surgery group, the adequacy of reduced
surgery, evaluation using a semi-quantitative CT evaluation
method, and clinical research such as joint resection of theaortic wall combined with stent-graft insertion are being
examined and conducted. In Japan, we participate in andregister cases with the Japan Clinical Oncology Group(JCOG) and strive to contribute to the development of lungcancer surgical treatment. The Niigata Respiratory Surgery
Research Group has been formed in Niigata Prefecture andhas started a joint randomized comparative trial with otherfacilities. In basic research as well, we are collaborating withother departments on research such as gene analysis using
next-generation sequencers.
The Pediatric Cardiovascular Surgery Group conducts
clinical research, including a review of the remote outcomesof surgical treatment for complex cardiac malformations, andpublished reports both in Japan and overseas. Participating inresearch using the synchrotron radiation phase-contrast CT
method in multicenter joint research, we have made many
presentations on the results in the successful visualization of
the impulse conduction system.
The Adult Cardiovascular Surgery Group is working on the
research and development of stent grafts with a new concept.
The Group succeeded in transplanting the developed stentgrafts into large animals. We participated in a clinical trialof a new stent graft treatment in Japan. Currently, we arepreparing to participate in clinical research in the future.

Orthopedic Surgery and Rehabilitation
Professor KAWASHIMA Hiroyuki

Orthopedic surgery widely works on clinic, researchand education, targeting motor organs such as
bones and joints.
Orthopedic surgery deals with musculoskeletal organs
like bone, cartilage, joints, muscles, tendons, ligaments
and other exercisers. Our subspecialty groups are as
follows; 1) spinal surgery, 2) lower extremity such as
hip joint, knee joint, 3)sports medicine, 4) pediatricorthopedics, 5) osteoporosis and bone metabolism,6) bone and soft tissue tumors, 7) hand surgery andmicrosurgery, 8) trauma including fractures and soft
tissues, pelvis, spinal cord injury, and 9) rheumatoid
arthritis and other joint disorders. Our department oforthopedic surgery is the fourth oldest in Japan and2017 marked our 100th anniversary lecture. In clinicalresearch, we are engaged in a lot of large-scale, highevidence-level research such as an epidemiologicalsurvey of proximal femoral fractures in all of Niigata
prefecture, Matsudai knee osteoarthritis survey, theSado project, and multicenter collaborative researchon spinal deformity in patients with rheumatoid
arthritis. In basic research, the tumor and rheumatoidgroup is conducting state-of-the-art research, fullyusing biomolecular procedures. Preoperative threedimensional planning and intra-operative support
using special jig for the knee and hip joint diseases,
rehabilitation research and clinical research are also
being conducted.

Pediatric Surgery

Professor KINOSHITA Yoshiaki

We research focusing on pediatric surgical diseases.
We mainly study adolescent surgical diseases fromnewborns to 15-year-olds.

Plastic, Reconstructive
and Aesthetic Surgery

Professor MATSUDA Ken

We conduct basic research on peripheral nerve
regeneration, lymphatic regeneration and woundhealing, and clinical research on reconstructive
surgery.
In our clinical practice, we are responsible for advanced
reconstructive surgery using microsurgery, treatment ofcongenital anomalies such as cleft lip and palate, facial
palsy, facial bone fractures, extensive burns, intractableulcers, and skin laser treatment, etc.
We are also engaged in basic research that directly
leads to the development of new surgical techniques.
These include research on the mechanism of plasticity inperipheral nerve regeneration for reconstructive surgery
of facial nerve or brachial plexus, research on woundhealing, research on simulated and model surgeries forreconstruction of the upper and lower jaw, and researchusing artificial intelligence. In addition to lectures about
general plastic surgery, we are in charge of several
lectures on dermatology and plastic surgery, lectures on
musculoskeletal system, and clinical practice. We arealso committed to microsurgical education and actively
provide all medical students, as well as residents, andgraduate students, with instruction in microscopic
microvascular anastomosis and other techniques underthe microscope.

adult (AYA ) generation, we are developing standard treatments
by stratifying risks for patients with rhabdomyosarcoma andEwing's sarcoma in the AYA generation as well as researching
pregnancy for solid cancer and treatment considering latecomplications. We are also working on creating treatment
guidelines for congenital intractable rare urogenital diseases,

establishment of a nationwide registry and development of
We are focusing on the research of pediatric surgical new surgical forms. As basic study, we are researching drugdiseases for children, who are our future.
resistance mechanisms using hepatoblastoma cell lines andOur main research in ​​pediatric tumors is the clinical specimens of hepatoblastoma as well as islet cell
development of a new diagnostic system using an transplantation for type 1 diabetes that develops in childhood.
immunological sugar chain analysis method for pediatricOur mission is to radically cure surgical diseases in children,solid malignant tumors, investigations into refractory from diseases that affecthemangiomas, vascular malformations, lymphangioma, many children to thoselymphangiomatosis and related diseases, as well as that are extremely rare
research to establish a treatment method using silolimus, and have poor prognoses.
which is a new treatment for intractable lymphatic
abnormalities. For the study of the adolescent to young17

Dermatology

the development of the novel therapeutic drugs targeting
proteins and receptors related to the epidermal cell death,

Professor ABE Riichiro

We study the elucidation of developing mechanismsof severe drug eruptions, and the identification of
the causative genes and the functions of hereditaryskin diseases.

and the new severity predictive markers. Meanwhile, thehereditary skin disease group identifies the causative genesof genetic skin diseases and analyzes their functions.

Currently, our laboratory promotes two research
projects. One is the severe drug eruption group whichtargets severe cutaneous drug reactions, specifically
toxic

epidermal

necrolysis

andStevens-Johnson

syndrome. Although the patients suffering from these
diseases can be fatal, the pathogenesis has notbeen fully elucidated yet. We particularly focus on

Urologyantibody-mediated rejection.

Professor TOMITA Yoshihiko

We proseed basic and clinical research on
urological tumors, renal transplantation andpediatric urological diseases.
Our laboratory focuses on research based on not
only “bench-to-bedside” but also bedside-to-bench.” In
urological tumors, we are also engaged in new drug
development, including participating in global clinical

We are examining the diagnosis of congenital urinarygenital diseases for children as well as the treatment
process and results. Most treatments for congenital urinarygenital disorders are surgical treatments, which are plastic
surgery aimed at preserving functionality. By retrospectively
examining many cases, we can obtain information regarding
the surgery timing, surgical methods and postoperative
follow-up methods, which is useful for more effective medicalcare.

trials on the brand new anti-cancer drugs such as
immune checkpoint inhibitors. In the fieldof renal transplantation, our research is
focused on several issues, namely, thedevelopment of antibody titer measuringsystem using sugar chain array in ABOincompatible kidney transplants, anti-HLA
antibody inhibitory effect by the anti-IL-6
receptor antibody, and a clinical study
on bortezomib medication in chronic

Ophthalmology

Professor FUKUCHI Takeo

We are focusing on glaucoma. Our research utilizes
our experience from many clinical cases and our large
number of operations which are notable in Japan.
Vision is very important for people to live. The
importance of healthy aging is frequently talked
about in our modern aging society. However, people
develop ocular diseases with aging, which often
greatly influence the daily life of the elderly. In recent
years, ophthalmologic instruments and therapeutictechniques have significantly improved, so very finelesions have been found and treated in an early stage.
18

We introduce the forefront technology at all times and workon the treatment and research of ocular diseases of all ages
from baby to the elderly. We teach the function of visionand its importance through the lecture, and our role is tohave students feel the fascination of the most advanced
microsurgery through practical training.

Otolaryngology - Headand Neck Surgery

Professor HORII Arata

Our research is covering the broad area of ENT
topics from hearing loss to carcinogenesis.
There are three research groups in collaboration
with the basic medicine department, we are continuingresearch that can be applied from basic research toclinical practice. We are also implementing industryacademia joint research.
Audiovestibular group is working to elucidate thepathophysiology of chronic vertigo, which is difficult todiagnose, and to develop treatment methods basedon Professor Horii’s work. He is on the International
Diagnostic Standardization Committee for Psychogenic
Vertigo in the Barany Society. In addition to clinicalRadiology andRadiation Oncology

Professor ISHIKAWA Hiroyuki

We research into the fields of radiation oncology,
diagnostic radiology, and medical physics.
In diagnostic radiology, we are particularly focusedon medical image evaluation. We are currently working
with other clinical departments on diagnostic imagingof tumors using deep learning, one of the artificial
intelligence technologies. In radiation oncology, we
mainly conduct clinical research such as research on
cognitive functioning after brain metastasis radiotherapy
and research on high-dose-rate interstitial irradiation
for prostate cancer. We also cooperate with clinicalresearch led by other departments and co-medicals inorder to play a role in the multidisciplinary treatmentof cancer. In medical physics, we are researchingdevelopment of an individualized QA system for
IMRT treatment patients applying delta-radiomics,
development of a high-precision dose evaluation
system considering uncertainty factors of radiotherapy,
development of a biological dose evaluation system
considering irradiation time, and development of ultrahigh-precision irradiation position verification methods
that consider the tumor control rate in stereotactic
brain radiotherapy.

research, we implement physiological and biochemical
research using animal models as well as functional analysis
using functional MRI.
Nose and throat group is researching the relationshipbetween olfactory dysfunction and cognitive function, which
may lead to the use of olfactory function test as a sensitive
biomarker to point early stage Alzheimer type of dementia.
Oncology group is dispatching graduate students inexperimental pathology to identify new moisturizing andtransposable controlling elements in head and neck cancer
and to conduct molecular pathological analyses of the detailed
control mechanism. We also participate in nationwide multiinstitutional

joint

researchandconduct

multipleclinicalresearch

projectsled

byour department.

Obstetrics and Gynecology

Professor YOSHIHARA Kosuke

We are working on clarifying the pathogenesisof obstetric and gynecological diseases anddeveloping new therapeutic strategies by using
integrated OMICS data analysis.
We are working on clarifying the pathogenesis ofobstetric and gynecological diseases and developing
new therapeutic strategies by using Integrated OMICS
data analysis and molecular biological analysis . Here
we introduce our research on endometriosis andgynecological cancer as follow:
1. Identification of endometriosis pathogenesis
Endometriosis affects 5 to 10% of women of reproductive
age in Japan, and causes chronic pelvic pain, dysmenorrhea,
and infertility, leading to decreased quality-of-life (QOL).
However, the pathogenesis of endometriosis remains
unknown. We have performed whole exon sequencing
for endometriotic epithelium and normal uterine
endometrial epithelium to identify endometriosisassociated gene mutations. We are now working tofurther elucidate the pathogenesis of endometriosis.
2. Development of molecular targeted therapy for
gynecological cancer stem cells
Cancer stem cells which are characterized by tumorigenicity,
self-renewal and differentiation capacities, are involved incancer proliferation, metastasis chemotherapy-resistance.
We are working on developing novel therapeutic strategies
for gynecological cancer by identifying therapeutic target
molecules for gynecological cancer stem cells.

19Anesthesiology

Professor BABA Hiroshi

We are studying the action mechanism of analgesics
on the transmission of pain sensation information in
the spinal dorsal horn and the brain, and the motor
function of the spinal anterior horn cells.
Our research uses electrophysiological techniquessuch as patch clamping and morphological techniquessuch as immunostaining. We focus on the plasticchange mechanism that occurs at the spinal dorsal
horn or at the brain level due to the inflammation of
peripheral tissues and nerve damage as well as theclamping, we also perform in vivo patch clamping if necessary,
which enables us to see the reaction of the spinal dorsal
horn cells to physiological stimulation. We also succeededin visualizing the pain sensation information transmitted tothe membrane potential and theintracellular Ca2 + imaging spinal
dorsal horn, using a spinal cord
slice as shown in the photograph.
Recently, we conducted in vivo
flavin protein fluorescent imaging toobserve the activity of spinal dorsal
horn cells and the somatosensory
area of the cerebral cortex.

action mechanism of analgesics that act at the spinal
cord level. We are studying the action mechanism of
drugs on motor function using the same method fromthe spinal anterior horn cells. Regarding the patch

Emergency and Critical Care Medicine

Medical Oncology

We rise to challenges from digital science to

We are researching the pathophysiology of cancer
and cancer drug therapy, and lung regeneration
using pluripotent stem cells.

Professor NISHIYAMA Kei

molecular biology and ethics to address acutemedical care from multiple perspectives.
We are conducting data science in acute medical

Our department conducts cancer drug therapy forcare in a wide range of ways from analyzing asolid tumors across organs. We provide drug therapy

cardiopulmonary arrest database of about 1.93 million

for cancer patients with complications and provide

people to artificial intelligence analysis of head CT

treatment based on cancer genetic testing. Basedimages. We are developing and demonstrating digitalon cancer registries and treatment data, we analyzetransformation such as an emergency consultation

the characteristics of cancer in the elderly and the

support application, an information sharing systemeffects and side effects of cancer drug therapy.

using SNS for emergency medical helicopters, and a

We also research focusing on the pathology ofremote ICU. In addition to participating in clinicalthromboembolism in cancer patients. Recently, we

research, we also provide guidance to other research

are working with other institutions to develop devices

institutes regarding the planning and implementationthat can easily measure the blood concentration ofof clinical research. Furthermore, in collaboration withmolecular-targeted drugs, which are the mainstay

the Department of Neuroanatomy, we are workingof cancer drug therapy, and to apply them clinically.

to combine the perspective of molecular biology

Pluripotent stem cells can differentiate into various

with knowledge obtained from data science. We

tissues. We are researching jointly with researchers in

also

over

other fields to proceed with research on lung organ

research

regeneration deriving from pluripotent stem cells usingpresidemulticenterto evaluate the current
state

of

advancedcare planning in acutecare settings and todevelop new tools.

20

Professor SAIJO Yasuo

blastocyst complementation in lung-deficient mice.

Clinical Pathology

Professor AJIOKA Yoichi

Our department is engaged in morphological analysis
and study of human digestive pathologies using
immunohistochemical / molecular biological techniques.
We focus on morphological analysis and conduct
research that can be applied to routine diagnosis. We
observe a single lesion in detail, find a region that has
different morphological changes within the same lesion,change and the protein expression / gene change, we carryout protein expression analysis using immunohistochemistry
and genetic analysis using molecular biological techniques.
Diagnosis(usingsurgicalmaterials,

macroscopic

photographs and gross descriptions) of abundant digestiveorgan disease cases (about 60,000 surgical materials, about
300,000 biopsies and materials for endoscopic examination)
are stored in the database of our department, enabling
various research on rare diseases and management of largescale analysis on common diseases.

and analyze each region. There is a function change inparallel with a morphological change that can be seen
with the naked eye and microscopically (tissue andcell levels). Protein expression and gene changes are in
the background of the morphological change. In orderto clarify the relationship between the morphological

Neurosurgery（Brain Research Institute）Professor FUJII Yukihiko

We provide highly advanced neurosurgicaltreatment merging our proud tradition withadvanced technology, and conduct basic research
focused on addressing clinical questions.

treatment using patient-derived brain tumor cells, (2)development of tumor diagnostic methods using cell-free
DNA obtained from body fluids such as cerebrospinal fluid,(3) elucidation of the regeneration and growth mechanismsof human nerve axons, (4) development of surgical supportand educational training systems to ensure the success ofhighly difficult neurosurgical operations, (5) establishment of
intraoperative visualization method of nerve activity areas

The Department of Neurosurgery, Brain Researchbased on flavin protein imaging, (6) analysis of blood flow

Institute, Niigata University, was established in 1953

in cerebral aneurysms using computational fluid dynamics,

as Japan's first independent neurosurgery programand (7) research on elucidating the pathogenesis of epilepsy

by Dr. Mizuho Nakada, who is known as the father

in collaboration with the Epilepsy Center of Nishi Niigata

of neurosurgery in Japan, and it has been leading

Central Hospital.

Japan in medical care and research. Research isborn from questions that arise in clinical practice.
Feeding research back to clinical practice has been
the concept from the beginning of the establishmentof the Brain Research Institute. Current research
topics include (1) research to elucidate the optimal

Neurology（Brain Research Institute） Professor ONODERA Osamu

Using clinical information, state-of-the-art analysis
methods, and brain tissue, we aim to overcome
neurological diseases based on molecularmechanisms.
We have investigated the causes and pathogenesisof various neurological diseases such as Niigata

and cell biological techniques. In particular, research withneuropathological tissue samples is a hallmark of our team.
In

recentyears,

cutting-edge

researchinmedicalbiology has become interdisciplinary. In other words, thecategorization of research topics by disease name is now
a thing of the past. And a more multifaceted perspective
is required. We hope to continue to lead the world in
conquering neurological diseases through cutting-edge
fusion pathology research.

Minamata disease and SMON disease. Many of ourpredecessors have started their research to understandthe causes of neurological disorders in their dailyclinical practice. We are studying in collaboration with
the Brain Research Institute laboratories; they havebeen conducting research using genetic, biochemical,
21

Cell Biology（Kidney Research Center）

Proteinuria is both the most important symptom of renal
disease and an aggravating factor that advances renal failure,

Professor KAWACHI Hiroshi

and is involved in the onset of other organ diseases such as

The Department of Cell Biology, Kidney ResearchCenter conducts basic research to elucidate thepathogenic mechanism of kidney glomerulardiseases and to develop novel therapy for nephrotic
syndrome, one of the most important disease innephrology field.

proteinuria leads to reducing the number of patients withKidney disease is regarded as a new national disease.

cerebrovascular and cardiovascular disorders. Suppressing
renal failure, brain stroke, and myocardial infarction. We were
the first in the world to identify the site responsible for the
onset of proteinuria and to elucidate its molecular structure.
We are currently conducting research to develop new
therapeutic methods targeting these molecular groups.

In our laboratory in the Basics Division of the Kidney
Research Center, medical professionals such as clinicians,
veterinarians, and pharmacists as well as basic biologists
are working together to elucidate the pathogenesis of
kidney disease and to develop new treatment methods.
Currently, the most important issue we are working onis the elucidation of the pathogenesis of proteinuria.

Clinical Nephrology and Rheumatology

Bioinformatics（Medical AI Center）

Our task includes clinical practise, researchand education in the area of nephrology andrheumatology.

We research knowledge extraction from omics
data and its technology development using
computers.

A wide range of basic and clinical investigations andBioinformatics is a field that conducts medical andeducation is in progress to understand pathogenesis

biological research using computers. We process

and to develop new treatment strategies for kidney

DNA and protein sequences on computers to study

diseases and autoimmune diseases. To acomplish

the genes and genomes of living organisms. Since

these purposes, we apply clinicopathological methods,

the intestinal microbiota is closely related to humanas well as varieties of experimental techniques, such as

health, we search for disease-related bacteria frommolecular and cellular biology, genetic and proteomic

the intestinal environment metagenomic data. In

analysis, and those with experimental animal models.

addition, we are developing technology to realize

Particularly, we have performed extensive researchprecision medicine that enables each patient to selectand published many papers on the development

the optimal treatment method in cancer genomics

and progression of IgA nephropathy, one of the mostresearch that investigates DNA mutations in cancer

predominant

glomerulonephritis.

cells. In recent years, we have developed further

We have also contributed greatly in the research

and are engaged in developing artificial intelligenceon the influence and treatment of uremic toxins on

for medical use. When using a computer, the data

complications in patients with end stage kidney

to be handled must be neatly organized. Databasedisease. Our department belongs to the Kidneyconstruction for that purpose is also a subject of our

Research Center. It is the sole institute in Japan that

research and development.

（Kidney Research Center）Professor NARITA Ichiei

type

of

primary

consists of basic, translational and clinical department.
Each department specializes in research about kidneydisease covering from basic to clinical science, working
in a coordinated fashion.

22

Professor OKUDA Shujiro

Medical Education Center

Professor SOMEYA Toshiyuki

We are working on promoting medical education,international exchange, and diversity.
In medical education, we are involved in the curriculum
for all years of medical school, from the first year's"Introduction to Medicine" and "Early Medical Practicum"
to support for clinical training in the final years of medical
school. We are also involved in student support. We
provide meticulous support for student concerns andoffer individual sessions at the Asahi-machi Campus
Medical Student Support Counseling Room.
In terms of international exchange, students fromJapan, Russia and China participate in the Summer

Medical Student Exchange Program during the summer
holidays. We have also accepted students from Sri Lanka since2017. For students who are dispatched to Russia for medical
research training and clinical training, briefing sessions andindividual consultations are held as in the summer program
in cooperation with the academic affairs section so that they
can stay Russia with peace of mind.
We also engage in diversity activities. We run an association
called Hitohiro no Kai that regularly holds the Hitohiro Cafe
where people with various positions can discuss problems andworries, including issues for female doctors in their work. A
wide range of people
from professors tostudents participate.

Disaster Medical Education Center

Myanmar Infectious Disease Research Center

This organization specializes in disaster medicine andhumanitarian medical support activities in Japan andoverseas. The center director is Medical School Dean
Toshiyuki Someya.

We will explain the actual situation of infectious
diseases in Myanmar, which is said to be a blank area,
and contribute to controlling infectious diseases andcultivating young human resources in both Japan and
Myanmar.

Specially Appointed Prof. TAKAHASHI Masashi

Our Center is one of the few organizations in Japanthat specializes in disaster medicine and medical
treatment. We implement disaster response,
humanitarian support activities, and research
activities in Japan and overseas in collaboration
with the department of Disaster Medicine andMedical Personnel Development in the Graduate
School of Medical and Dental Sciences and the
Research Institute for Natural Hazards and Disaster
Recovery, Niigata University as well as humanresource training for undergraduate students andinterprofessional workers. We also play a leadingrole in Japan DMAT (Disaster Medical AssistanceTeam) personnel training and the international
disaster relief team’s medical training of JICA
(Japan International Cooperation Agency). The
disaster medical education model promoted by
our Center has been selected as one of the best
initiatives (GP: Good Practice) among the education
reforms promoted by the Ministry of Education,
Culture, Sports, Science and Technology for two
consecutive terms, from 2014 to 2018 and from2018 to 2022. We play a central role in disastermedicine and medical treatment in Japan. In
response to COVID-19, we have set up a patientadmission coordination center at the medical
coordination headquarters in Niigata Prefecture
to contribute toward streamlining the medical
systemfromthe perspectiveofdisastermedicineandsocial medicine.

Professor SAITO Reiko

Niigata University established a research base (officeand virus laboratory) at the National Institute of Health inYangon, the largest city in the Republic of the Union of
Myanmar, in 2015 as one of the overseas infectious diseaseresearch sites of the Japan Agency for Medical Researchand Development (AMED). We also conducted molecularepidemiological studies on influenza and other respiratory
infections including the novel coronavirus (SARS-CoV-2),
severe pediatric pneumonia, pediatric diarrhea, andpediatric meningoencephalitis, and monitored the risk of
their spreading into Japan. Myanmar, like other Southeast
Asian countries, experienced an explosion of several wavesof SARS-CoV-2 from April 2020, making it impossible forJapanese to travel to Myanmar. Furthermore, due to thepolitical change in February 2021, its medical environment
fell to a lower level. Even under such circumstances, we havemaintained our investigation and research on respiratory
diseases by making use of web conferences and cooperatingwith local medical institutions, counterparts, and local staff.
The current SARS-CoV-2 pandemic has made it clear to theworld that infectious diseases know no borders. It has long
been pointed out that the medical system in Myanmar isvulnerable, making it a blank area for infectious diseases.
Since 2018, we have been implementing a short-termsummer training program in which medical students fromJapan and Myanmar caninteract using this base.
We are working to foster
doctors and researcherswith a global perspective
on infectious diseases.

23

Histopathology Core Facility
Professor AJIOKA Yoichi

As a joint facility of a medical department, we prepare
tissue specimens, support research and education
related to the specimens, and store and manage
materials for research and education.
This facility was established in September 2015 for contract
preparations of histopathological specimens (experimental
animals and plants included) for research, research andeducation support related thereto, and preserving andmanaging research and educational materials. Our main
business lineups are preparing formalin-fixed paraffin sections
and frozen sections, preparing histopathological specimens(prepared specimens) for microscopes such as HE stainingof tissue specimens, cultured cell samples, histochemistry
andimmunohistochemistry,pathologists
evaluating
pathological tissue, photographing on a macro-micro level,
making virtual slides and paraffin block storage. We hopeto go beyond contributing to medicine, dentistry and drug
research, to also conduct research, product development
promotion, and educational support in all experimental andresearch fields including agriculture and food relationships,
science and industrial product development. We offer freeconsultations and hope you will come to us for one.

Niigata Regional Medical Support
Center Medical Branch OfficeSpecially Appointed Assistant Professor MIZUSAWA Takeshi
We provide training and career development support for doctors whoshoulder regional medical care, cooperating with the Niigata Prefectural
Health and Welfare Department and the Niigata Medical Association.
Our Center holds community medicine summer
training every August for students who receive theNiigata Prefecture Doctor Training Fund and students
who are interested in community medicine. In addition
to being able to actually experience the atmosphereof the local medical field, they can form a resource
network that can be used even after graduation

Cause of Death Education Center

Professor TAKATSUKA Hisakazu

We are conducting advanced studies on the causesof death and fostering professionals participatingin the studies with the goal of building a safe andsecure society.
The center was established in July 2017 as one baseto solve social problems such as increasing deaths due
to aging, overlooking crimes and responding to largescale disasters. Accurate investigation into the cause ofdeath is important for protecting the dignity and rights
of individuals. However, the investigation system of thecause of death in Japan is not perfect and is severely
suffering from a personnel shortage. The center consistsof five departments: the Forensic Pathology Department
24

PAS stain (mucin stain)
Photomicrograph: Mucus
in human colon cancer ishighlighted as a magenta color
in PAS stained specimen.

Berlin blue stain (iron stain)
Photomicrograph: Asbestos
found in human sputum

Oil red O stain (lipid stain)
Specimen: Human fatty liver

Ziehl-Neelsen stain (used forstaining tubercle bacilli)
Photomicrograph:

Mycobacterium tuberculosis

bacilli phagocytosed by humanmacrophage are highlighted
as a magenta color in ZiehlNeelsen stained specimen.

because medical students from other universities gather
together to inspire each other and build relationships. We
also regularly hold a “Learn about Niigata Medicine” seminar
to deepen understanding of the current state of community
medicine in Niigata Prefecture in collaboration with the
Niigata Medical Association and the Niigata Prefecture
Welfare and Health Department. We will implement
activities based on the opinions and wishes of participating
students. Please feel free to contact us. We will continue
working so that more students will participate and convey
the appeal of community medicine.

that performs medical examinations, and pathologicaldiagnoses, the Imaging Diagnosis Department that performs
postmortem image diagnoses by CT, the Medicinal Toxicant
Biochemistry Department that analyzes alcohol and medicinal
toxicants, the Dental Jurisprudence Department that confirms
the body identification through dental exams and the Social
Forensic Department that responds to abuse. The center
is fostering personnel as they implement more advanced
investigations into the cause of death in cooperation withrelated organizations inside and outside the university.
Strengthening the investigation system of cause of death andimproving its quality are extremely important. The center
is working to contribute to the local community as a corefacility on the Seaof ​​Japan coastand in Japan in theinvestigation of thecause of death.

Center for Research Promotion
Professor SOMEYA Toshiyuki

We promote vitalization of medical research at the
Niigata University School of Medicine through common
equipment management and technology provision.
The Center for Research Promotion, School of Medicine,
Niigata University (Research Promotion Center) wasestablished on the third floor of the Faculty of Medicine
Joint Research Building to further promote medical
research at the Niigata University School of Medicine.
Full-time staff (one faculty member, two technical staff
members) provide support for a wide range of medical
research. In addition to maintenance and managementof common equipment ranging from general-purpose
equipment to large equipment (electron microscopes,
mass spectrometers, cell sorters, fluorescencemicroscopes, etc.), we provide research support
services using equipment that requires specialized skills.
Seminars and training on research methods are alsoscheduled to be
held.

Collaborative Research Laboratory
Applied Molecular Medicine

Specially Appointed Prof. SAITO Akihiko

Biofluid Biomarker Center

Specially Appointed Assoc Prof. YAMAMOTO Keiko

Clinical Nutrition Science

Specially Appointed Assoc Prof. HOSOJIMA Michihiro

Donated Fund Laboratory
Community Medicine
Division of Human Resource Development for Community Medicine
Community Medicine
Division of Community Medicine

Specially Appointed Prof. IGUCHI Seitaro

Community Medicine

Division of Disaster Medicine and Medical Professionals Development
Specially Appointed Prof. TAKAHASHI Masashi

Health Promotion Medicine

Specially Appointed Assoc Prof. ITO Yumi

Laboratory Medicine and Clinical Epidemiology for
Prevention of Non-communicable Diseases
Specially Appointed Prof. KATO Kiminori

General Medicine

Specially Appointed Prof. KAMIMURA Kenya

We train doctors who have comprehensive medical
skills and can handle the multiple diseases and life
challenges of all patients.
We promote a General Practitioner Training Programthat trains doctors to acquire a wide range of medical
knowledge to examine the whole body and to provide
holistic medical care considering patient feelings. In
the clinical participation training of medical students,
technical skills such as specialized knowledge and clinicaltechniques are taught in cooperation with medical
institutions in Niigata Prefecture. We are also providing
opportunities to learn human skills such as leadership,
management, and communication using online andon-demand learning. Using this education system, theNiigata Method, we would like to provide the skills
necessary for team medical care and leadership, andcontinue to develop general practitioners who protect
the community in collaboration with multi-professionals.
The major goal of our lab is to train generalpractitioners in Niigata who emphasize the stanceof clinical examination, community protection, andpatient consideration; and to work with various people
gathering from all over Japan.
Please be sure to visit our website.

Our Web

Advanced Cardiopulmonary Vascular Therapeutics
Specially Appointed Assoc Prof. KASHIMURA Takeshi
Community Psychiatric Medicine
Specially Appointed Assoc Prof. SUGIMOTO Atsunori
Health Sciences for Prevention and Management of
Non-communicable Diseases
Specially Appointed Assoc Prof. FUJIHARA Kazuya
Inter-Organ Communication ResearchSpecially Appointed Assoc Prof. WAKASUGI Minako
Familial and Hereditary Oncology

Specially Appointed Assoc Prof. NISHINO Koji

Preemptive Medicine for Digestive Diseases and Healthy Active Life
Specially Appointed Assoc Prof. YOKOO Takeshi
Community Medicine and Clinical Data Analysis
Specially Appointed Assoc Prof. KITAZAWA Masaru
Advanced Treatment and Prevention
for Vascular Disease and Embolism
Specially Appointed Prof. HANZAWA KazuhikoMusculoskeletal Science for Frailty

Specially Appointed Assoc Prof. KOGA Hiroshi

Department of Network Medicine for Digestive Diseases

Specially Appointed Assoc Prof. KAMIMURA Hiroteru

Department of Preventive and Minimally Invasive Medicine for
Digestive Diseases, School of Medicine, Niigata University

Specially Appointed Assoc Prof. HAYASHI Kazunao

Division of Comprehensive Musculoskeletal Medicine, Niigata
University Graduate School of Medical and Dental Sciences

Specially Appointed Prof. IMAI Norio

Department of Active Ageing (donated by Tokamachi city, Niigata Japan)

Specially Appointed Prof. SHOBUGAWA Yugo

Next-generation care medicine for Information andcommunication technology (ICT)Specially Appointed Assoc Prof. OSAWA Taeko
25

INTERNATIONALEXCHANGE
Niigata University is located near the Port of Niigata which was
one of the first five ports (Niigata, Hakodate, Kanagawa, Hyogo,
and Nagasaki) opened its doors to the world from an early age
in Japan under the Treaty of Amity and Commerce between
the United States and Japan (1858). Niigata University actively
promotes international exchange in education and research witha lot of universities around the world.
Undergraduate and graduate students are provided with a varietyof opportunities to study abroad. We also welcome international
students from a wide variety of countries all over the world every year.
One of the main features of international exchange in Niigata
University is that we have strong connection not only with Westerncountries, but also with neighboring countries, using Niigata's

geographical and historical advantages. Even during the COVID-19
pandemic, when face-to-face exchanges were stagnant, online
exchanges among students were actively conducted with many
universities abroad.
Through our international exchange activities, we place theutmost importanceon fostering global
medical professionals
and researchers who
can play active roles
on the world stage.

Exchange partner schools of the Faculty of Medicine
Denmark

SwedenTechnical University Karolinska Medical University Moscow State Universityof Denmark St. Petersburg University Kazan Federal University
UK
North-Eastern Federal University
kazan State Medical University
Kings College
Sechenov First
Russian Federation
University of Leicester
Moscow State
Krasnoyarsk State Medical University
University of Bristol
Medical University

Concordia University

CanadaBrigham and Women's Hospital
Mongolian National University of Medical Sciences
Harvard University Children's Hospital Cincinnati Children'sHarbin Medical University Far Eastern State
University of Michigan Hospital Medical
Medical University
Qiqihar Medical University
CenterSwiss Federal Institute of Technology
Mongolia
The National
University of Illinois at Chicago
Yanbian University
Zhengzhou
University Hospital of Zurich
Institutesof HealthPaciﬁc State Medical University
University
Germany
University of Lausanne
New
York
University
University of
University of Lisbon
Dalian Neusoft University Dalian Minzu University
Hebei
University of California
Columbia University
China Medical University Graduate School
University
Minnesota
University of Cagliari
China
UniversityofPennsylvania
Fujian Agriculture and Yangtze University
University of California,
Nanchang University
China Southern Medical University
Wuhan University of Science and Technology San Diego SchoolJeﬀerson Medical School
Switzerland
Forestry University
National Xiamen University
University of Virginia
Taiwan University
MD Anderson Cancer CenterPortugal
Graduate School
Hainan Medical University
Gupta University of Technology
Italy
Virginia State University
University of Medicine, Magway
and Science Graduate School
The United States Johns Hopkins University
University of Medicine 2,Yangon
North Carolina State University
Massachusetts State University
University of Public Health, Yangon Myanmar
Wake Forest University
Bioengineering Laboratory
University of Medicine 1, Yangon
Vietnam
Rutgers
University- Massachusetts
Egypt
General Hospital
Hanoi
Medical
University
UniversityofMarylandAl-Azhar University
India Sli Lanka
Universidade
doPham Ngoc Thach Medical University
Estado do Amazonas
Indonesia
Peradeniya University
Helmholtz Centre for Infection Research
University of Tübingen

Kenya

Ethiopia

Edgerton University

Addis Ababa University

Malaysia
Bangladesh

Airlangga University
Hasanuddin University

National University of Malaysia(Former University Kebangsan)

BrazilJahangirnagar University
North South University
Development Alternative University
University of Rajshahi

Thailand

Mahidol University【Characteristic activities】（１）
Europe and America
We are implementing exchange programs for studying
abroad with multiple universities, including the University ofLeicester in the UK, in which we mutually exchange students forthe clinical training. In medical research training, more than ten
students participate in cutting-edge basic research for about
two months at various European and American universities.
The School of Medicine has been vigorously working to
improve practical English skills by offering English conversation
classes taught by native speakers specializing in medical
English since 2014.
In order to support
students who intend
to work as doctors
overseas, we actively
provideinformation
on preparation for theUnited States Medical
Licensing Examination
26(USMLE). As a result, 17 students have passed the USMLE in thepast few years, including three 2021 graduates. In addition, we
invite top physicians and researchers who are active in Japanand abroad to give lectures on the current state of the world’s
top level medical care and diverse career paths.

（２）
Southeast and Southwest Asia
We are participating in educational and research exchanges
in the field of infectious diseases and global health, focusing on
influenza, and severe pneumonia and diarrhea in children. In
Myanmar, we collaborate with top-level institutions such as the
National Institute of Health, University of Medicine 2, Yangon,
and Mandalay University etc. In 2015, we were selected toparticipate in the Japan Initiative for Global Research Network
on Infectious Diseases (J-GRID) program of the Japan Agency
for Medical Research and Development (AMED), and weestablished an overseas research base in Yangon. In 2020, wewere also selected as one of the projects on the Emerging and
Re-Emerging Infectious Diseases at Overseas centers (Global

Research Infrastructure, Collaborative Research via Overseas
Research Centers), and are continuing to work on infectious
disease research in Myanmar. In 2019, short-term summer training
program started in Myanmar for undergraduate students. Niigata
University has accepted a number of students from Myanmar incooperation with other universities in Japan. Furthermore, withthe cooperation of the Universiti Kebangsaan Malaysia (National
University of Malaysia), we are conducting interactive exchanges
between Malaysian and Niigata University’s faculties, graduate
students, and undergraduate students. We also provide shortterm dispatch training for undergraduate students both in
Malaysia and in Japan. In Myanmar and Malaysia, we conductsocial epidemiological surveys on the health of the elderly andconduct international comparative research with Japan where
the aging population is increasing.
International Priority Graduate Programs for advanced
graduate course support for international students sponsoredby the Ministry of Education, Culture, Sports, Science andTechnology (MEXT) of Japanese government. In 2018,
Developmental Psychiatry program started to foster the leadersfrom the Southeast Asian (ASEAN) region. In 2021, a program
to foster medical and biological specialists in neuroscience
Country

University/Facility

Undergraduates

Graduates

Dispatched

Dispatched

University of Illinois at Chicago 3
Wake Forest University
2
MD Anderson Cancer Center
University of California
4
University of California, San
4
Diego School
Columbia University2
Jefferson Medical School
1
Johns Hopkins University
1
Cincinnati Children's Hospital
6
Medical Center
New York University
1
North Carolina State University 1
The United
Harvard University
8
StatesChildren's Hospital
Virginia State University
University of Virginia
Graduate School
Brigham and Women's Hospital
7
The National Institutes of Health4
University of Pennsylvania 1
Bioengineering Laboratory Massachusetts General Hospital
Massachusetts State University
1
University of Michigan
7
University of Minnesota
10
University of Maryland
1
Rutgers University
8
CanadaConcordia University
Universidade do Estado do
BrazilAmazonas
Kings College
1
UnitedUniversity of Bristol
2
Kingdom
University of Leicester
12
Portugal
University of Lisbon
1
Italy
University of Cagliari
1
University of Tübingen2
Germany
Helmholtz Centre for1
Infection Research
Swiss Federal Institute of Technology 5
Switzerland University Hospital of Zurich 3
University of Lausanne
2
Denmark Technical University of Denmark 1
SwedenKarolinska Medical University 1
University of Medicine 1, Yangon
Myanmar University of Medicine 2,Yangon 7
University of Public Health, Yangon

Accepted

Acceptedand system medicine was adopted, targeting ASEAN andSouthwest Asia. Together with a lot of international students
from many countries, we are actively engaged in mutual
exchange programs in the clinical and research fields.

（３）
China and Russia
The coastline of Niigata Prefecture facing the Sea of Japan
reaches 330 km on the mainland coastline, excluding remoteislands such as Sado Island. Niigata Port, located in the center ofthe coastline, has a long history of exchanges with countries on
the opposite coastline, such as China, South Korea, and Russia.
Niigata University has also become a gateway for international
exchanges between universities in these countries. Taking
advantage of this location, we have long history of activatedmedical education and medical care exchanges with various
universities in China such as Harbin Medical University as wellas medical universities in the Far East and Siberia. To date,approximately 400 students have mutually visited, and morethan 70 Chinese and Russian doctors and nurses have studied
medicine at our faculty.
Number of international students (2011 - 2021)

Country

University/Facility

Graduates
Dispatched

Accepted

Myanmar

1

1
1

1
2

1
1

5

2
1
1

University of Medicine, Magway
National University of Malaysia
Malaysia(Former University Kebangsan)
Gupta University of Technology
India
and Science Graduate School
Jahangirnagar University
Bangladesh Development Alternative University
University of Rajshahi
Sli Lanka
Peradeniya University
Thailand
Mahidol University
Airlangga University
Indonesia
Hasanuddin University
Hanoi Medical University
VietnamPham Ngoc Thach Medical University
National Xiamen University
Taiwan University
Qiqihar Medical University
China Medical University
Graduate School
China Southern Medical University
Harbin Medical University
Yangtze University
Wuhan University of
Science and Technology
China
Fujian Agriculture andForestry University
Dalian Neusoft University
Dalian Minzu University
Yanbian University
Zhengzhou University
Hebei University
Hainan Medical University
Nanchang University
Far Eastern State Medical University
Krasnoyarsk State Medical University
Pacific State Medical University
kazan State Medical University
Kazan Federal University
RussianFederation St. Petersburg University
North-Eastern Federal University
Moscow State University
Sechenov First Moscow State
Medical University
Egypt
Al-Azhar University
Ethiopia
Addis Ababa University
Kenya
Edgerton University

Undergraduates
Dispatched

Accepted

2
33

7
1

1

1
1
3

2
2
7
1
1

2

1

1

1
2

18

1
10
2

32

1
1
1
1

1
1

1

33
36
21

3

30
26
28
4
5
6
5
4

2
5
2
2

1
1
1
10
14
9
5

2

2
1
1
1
27

PROJECTS"COVID-19 Vaccine Development Using Recombinant
BCG (rBCG) Technology"
AMED Drug Discovery Support Promotion Project(2020-2021)
Amid the pandemic caused by the new coronavirus
infection (COVID-19), an inverse correlation
between BCG vaccination and the incidence andmortality of COVID-19 was indicated. As the resultsof large-scale epidemiological studies and theeffects of BCG vaccination against viral infections
and SARS-CoV-2 infections by double-blind tests
were later reported several times, there is growing
momentum to use the BCG as a countermeasureagainst COVID-19.
The BCG is an attenuated strain of mycobacterium
tuberculosis and is a live tuberculosis vaccine.
Since it survives in the body for several years
after inoculation, it can provide long-term immune
stimulation and has a strong adjuvant activity
necessary for vaccines. It is also highly safe and canbe manufactured at a low cost, as evidenced by therecord of having been administered to the greatest
number of people so far.
Niigata University possesses this BCG and virus
recombination technology, and has bioinformatics
know-how to track virus mutations. In cooperation
with the Institute of Medical Science, the University ofTokyo, the National Institute of Infectious Diseases,
Japan BCG Laboratory, and Tottori University, we
have developed a plan to express the SARS-CoV-2
spike protein from BCG and create a COVID-19
vaccine. This project was implemented from 2020
with the support of the Japan Agency for Medical
Research and Development.
Previously, rBCG used drug resistance markers
for genetic engineering. Since it is not appropriate
for human application, we aimed to create markerfree rBCG. Also, although BCG substrains exist, we
proceeded with preparation based on Japanese
BCG (Tokyo strain), which has a reputation forstability and antigenicity and is an internationalreference product of the WHO. Therefore, we
analyzed the gene expression pattern of the BCG
Tokyo strain and tested the design that maximizes
the efficiency of expression and secretion of theforeign antigen. As a result, we established amarker-free recombinant BCG, rBCG-70C2, that28

MATSUMOTO Sokichi

Professor
Principal Investigator
Department of Bacteriology,
Niigata University Graduate
School of Medical and Dental
Sciences,secretes the receptor binding domain (RBD) of the
spike protein. A patent application has been filed
for the preparation method of this rBCG.
rBCG-70C2 boosted antibody responses to the
RBD and maintained them for a long period of timeupon inoculation of spike protein RBD-immunizedanimals. Also, in a vaccine booster test in hamsters, it
was confirmed that the hamsters tended to recoverquickly after viral infection. We created a nonclinical formulation of rBCG-70C2 and conducted
toxicity tests to confirm its safety. Furthermore,through international joint research, the Institute of
Vaccines and Medical Biologicals (IVAC) in Vietnam,
which produces Japanese BCG, has manufactured aclinical trial formulation of rBCG-70C2.
This project is implemented with the supportof Niigata University's Clinical and Translational
Research Center, URA, and the Institute for
Research Promotion. We hope that the outstanding
technology and know-how of Japan, including
the technology and know-how of our university,
will contribute to controlling intractable diseases,
including COVID-19.

Niigata Training Method: General Practitioner Training
Program

KAMIMURA Kenya

Specially Appointed
Professor
Department of General
Medicine, Niigata University
School of Medicine

The aim of this project is to develop the humanresources who can take care the multiple diseases
and life-related issues of individual patients andprotect the community (life and lifestyle) throughcollaboration with multi-professionals. The humanresources include the general practitioner andthe project is called "Niigata Training Methods
for Generalist", and is supported by the Japanese
Ministry of Health, Labor and Welfare.
In order to promote this program, we opened
our lab and started the classes in January, 2021
collaborating with Niigata Prefecture, Niigata
prefectural Medical Associations, and medical
institutions in Niigata prefecture.
In clinical training, the core of this project, themedical students learn how to build up the skill of
examining the whole body and how to consider
patients. To teach comprehensive medical technicalskills, we are cooperating with physicians in Niigata
prefecture.

In addition to providing technical skills(professional medical knowledge and skills), thisclass also provides programs for learning humanskills. “Human Skills” include communication skills,
leaderships, presentation skills, development ofcooperation and team spirit, etc.
By promoting the project, we believe that theGeneral Practitioner will contribute to securing andimproving medical care in Niigata Prefecture.

Echo practice using a simulator

Summary of practical training that connects inside andoutside the university online

29

DATA

Number of Students (Undergraduate)
School ofMedicine（As of May 1, 2022）

Year

１st

２nd

３rd

４th

５th

６th

Total

Admission Quota

133

127

127

127

127

127

768

136

135

124

133

121

131

780

(29)

(26)

(32)

(35)

(24)

(41)

(187)

Enrollment( ) indicates female students

Number of Students (Graduate)
Graduate School of
Medical and Dental
Sciences(Master Course)

Course for Biomedical
Sciences（As of May 1, 2022）

Year

１st

２nd

Total

Admission Quota

20

20

40

11

15

26

(5)

(7)

(12)

Enrollment（As of May 1, 2022）

Course for Molecular
and Cellular Medicine

Graduate School of
Medical and Dental
Sciences(Doctor Course)

Course for Biological
Functions and Medical
Control
Course for Community
Disease Control

Year

１st

２nd

３rd

４th

Total

Admission Quota

22

22

22

22

88

18

36

24

50

128

(6)

(11)

(9)

(12)

(38)

37

37

37

37

148

36

52

36

60

184

(9)

(18)

(6)

(16)

(49)

14

14

14

14

56

8

4

5

10

27

(2)

(3)

(1)

(3)

(9)

72

72

73

73

292

62

92

65

120

339

(17)

(32)

(16)

(31)

(96)

Enrollment
Admission Quota
Enrollment
Admission Quota
Enrollment
Admission Quota

Total

Enrollment( ) indicates female students

Number of Foreign Students
Graduate School of Medical and
Dental Sciences (Master Course)（As of May 1, 2022）

Year

１st

２nd

Total

Course for Biomedical Sciences000（As of May 1, 2022）

Year
Graduate School of
Medical and Dental
Sciences(Doctor Course)
30

１st

２nd

３rd

４th

Total

Course for Molecular and Cellular Medicine

2

1

0

1

4

Course for Biological Functions and Medical Control

6

7

4

1

18

Course for Community Disease Control

5

0

1

5

11

Total

13

8

5

7

33

Number of Graduates

Number of Degrees Conferred（Master of Biomedical Science）

PeriodNumber of Graduates

College of Medicine (Old Educational
System)(Nov., 1914 - March, 1924)

964 （0）

Medical College(March, 1926 - March, 1954)

1,974 （3）PeriodGraduates

March, 2004 - March, 2022

263

Number of Degrees Conferred
Doctor of Philosophy（Medical Science）, Doctor of Philosophy
PeriodAttached Medical Special Course(Sept., 1942 - March, 1952)

661 （15）

University (New Educational System)(March, 1955 - March, 2022)

7,014 （1,198）

Total

10,613 （1,216）

The Whole Course
Completed

Doctors(Old Educational System)
1,888(Dec., 1923 - March, 1960)
Doctors(New Educational System)
2,267(March, 1959 - March, 2022)
Total

4,155

Total

ThesisPresented

1,888
1,822

4,089

1,822

5,977

( ) indicates female students

Successful Candidates of the National Medical Practitioners Qualifying Examination
Applicants

2017

2018

2019

2020

2021

127

110

135

129

133

Passed

120

106

129

118

129

Pass ratio (%)

94.5

96.4

95.6

91.5

97.0

Staff

（As of May 1, 2022）

DivisionsTeaching Staff
Professors

School of Medicine

38

Office Personnel

Assistant
Associate
Lecturers
Professors
Professors
33

10

55

Total

ClericalOfficials

136

18

Technical
Medical
Officials Technical Staff
13

0

Total
31

(Female)

(2)

(3)

(0)

(18)

(23)

(2)

(4)

(0)

(6)

(From Abroad)

(0)

(0)

(0)

(4)

(41)

(0)

(0)

(0)

(0)

2020
Items

2021
Items

External Funding
Category

Grant-in-Aid for Scientific Research on Innovative Areas

2018
Items

8

2019
Items

8

4

4

Grant-in-Aid for Scientific Reserch

Grant-in-Aid for Scientific Research(A)

3

4

6

4

Grant-in-Aid for Scientific Research(B)

20

19

24

34

Grant-in-Aid for Scientific Research(C)

68

78

48

62

Grant-in-Aid for challenging Exploratory Research

6

9

11

12

Grant-in-Aid for Young Scientists(A)

3

1

−

−

Grant-in-Aid for Young Scientists(B)

20

10

1

−

Grant-in-Aid for Young Scientists

12

34

30

35

Grant-in-Aid for Transformative Research Areas
（A）

0

0

1

2

Grant-in-Aid for Research Activity start-up

0

2

2

4

Fund for the Promotion of Joint International Research (Fostering Joint International Research)

0

0

1

5

Grant-in-Aid for JSPS Fellows

6

5

2

0

Subtotal

146

170

130

162

Health and Labor Sciences Research Grant

11

16

14

12

Joint research

24

33

24

16

Commissioned research

59

63

72

65

Donations

490

564

469

404

Total

730

846

709

659

Total Amount (Unit: ¥1,000)

1,717,561 1,877,471 2,261,877 1,865,756
31

Number of Autopsies and Body Donors
Divisions

2012

2013

2014

2015

2016

2017

2018

2019

2020

2021

Systematical

55

45

64

59

55

54

56

50

43

48

Pathological

33

22

41

31

25

25

42

33

14

18

Total

88

67

105

90

80

79

98

83

57

66

International ExchangeCountries

Foreign University

Date Concluded

United Kingdom

University of Leicester

February 28, 2017

People's Republic of China

Harbin Medical University

April 6, 1998

Far Eastern State Medical University

August 26, 1998

Pacific State Medical University

July 23, 1993

Krasnoyarsk State Medical University

September 11, 1998

kazan State Medical University

November 16, 2017

Kazan Federal University

November 17, 2017

North-Eastern Federal University

November 3, 2017

Moscow State University

December 21, 2017

National University of Malaysia

December 31, 2019

The Myanmar Ministry of Health

September 16, 2005

University of Medicine 2, Yangon

October 22, 2013

University of Medicine, Mandalay

June 27, 2018

University of Medicine 1, Yangon

July 27, 2020

Mongolia

Mongolian National University of Medical Sciences

July 14, 2014

CanadaConcordia University

December 12, 2013

Jahangirnagar University

December 16, 2016

North South University

April 11, 2018

Airlangga University

May 1, 2017

Hasanuddin University

July 25, 2018

Russian Federation

Malaysia

Republic of the Union of
MyanmarBangladeshIndonesia

32

BUILDINGLAYOUT△▼ Ｎ

Life Innovation Hub
Faculty of Dentistry

AmenityMall

Outpatient
Entrance

Outpatient wing
East
Ward

Yujin
Memorial Hall

1
3

4

Central wing
Medical and Dental
Hospital

Hospital
Entrance

5

2

9

6 7
8

Entrance
Extracurricular
Activity Club
Bldg.
Tennis Court

Integrated Research Bldg.
West
Ward

Medical and
Dental Library

IkeharaMemorial Hall

AnimalGene
Experimentation
Experimentation
Facility
10 Facility
CentralBrain Research
RI General
Power
Institute
CenterStationSchool of Medicine, Faculty of Medicine

Brain ResearchInstitute

Asahimachi
GymnasiumWest wingMulti-story
Parking Garage

GroundSchool of Health Sciences,
Faculty of Medicine
Entrance

School of Medicine, Faculty of Medicine

1 East Wing Building
2 West Wing Building
3 North Wing Building
4 East Lecture Building
5 West Lecture Building
6 Auditorium
7 Student Practicum Building
8 Joint Research Building
9 Niigata Medical Professionals
Development Center

10 Kidney Research Center

The Hippocrates Tree
33

The Sea of Japan
Niigata City Aquarium●
Gokoku Shrine●

Asahimachi Campus
Niigata University

116●NEXT21402

SekiyaBunsui
ChannelAoyamaStationSekiyaStationHakusanStationNiigata PrefecturalOﬃce●

Niigata CityOﬃce●
Niigata City
Performing Arts
Center ●Showa
Bridge

Sh

r

ve

Ri

●Shin Nihonkai FerryT

Sado Kisen Ferry Port●

Bandai
Bridge

113

ano

Riv

er

7

Shin
The

i

he

o

n
na

Joe

ain

t Tr

ulle

B
tsu

Line

Niiga

ta Station

How to reach the School of Medicine from Niigata Station【Bus】
Take the Bandai Exit from Niigata Station (JR East Japan Railway Company)
Take one of the following Niigata Kotsu buses at the bus terminal in front of Niigata Station▶C2 Hamaura-cho Line: Get off at Asahimachi-dori Ni-bancho (15 ‒ 20 minutes)
Walk about 3 minutes south from the bus stop.
▶C3 Shinano-machi Line: Get off at Shiyakusho-mae (City Hall)(15 ‒ 20 minutes)
Walk about 8 minutes north from the bus stop.
▶C8 Shindai Byoin Line: Get off at Niigata Daigaku Byoin (Niigata University Medical & Dental Hospital)(15 ‒ 20 minutes)
Walk about 5 minutes north from the bus stop.
【Taxi】
10 ‒ 15 minutes from Bandai Exit at Niigata Station (JR East Japan Railway Company)

An Outline of Niigata University
School of Medicine, Faculty of Medicine
Graduate School of Medical and Dental Sciences (Medicine)
Date of Issue: December 2022
Publisher: Administrative Affairs Division
Medical and Dental Programs
757 Ichibancho, Asahimachi-dori, Chuo Ward, Niigata City 951-8510
Phone: +81-(0)25-223-6161 (Main number)
URL https://www.med.niigata-u.ac.jp