March 26th, 2024
Nikko Chemicals Co., Ltd.

Satoshi Yoshimoto of Nikko Chemicals
Won the ASCS CONFERENCE 2024 Special Poster Prize:“Improvement of Sensitive Skin Through Multifunctional
Lysolecithin

Tokyo, March 19th, 2024 - Nikko Chemicals Co., Ltd. is pleased to announce
that Satoshi Yoshimoto, a researcher at our Central Laboratory, was awarded
the Special Poster Prize at the Asian Societies of Cosmetic Scientists (ASCS)
Conference 2024.
ASCS was established as a federation of cosmetics specialist associations inAsia, Oceania, and the Middle East to promote the development of the cosmetics
science and industry by deepening the interactions among academic
communities in these three regions.
The conference is held biennially, and this yearʼs conference was held for threedays starting on March 6 in Goa, India. Oral and poster presentations wereorganized, and technical and cultural exchanges took place. PhD. Yoshimoto,our researcher at the Skin Evaluation Group of the Evaluation and Analytical
Technology Development Office in the Central Laboratory, received a special
award for his poster presentation.
Upon receiving this award, Mr. Yoshimoto commented “I am very pleased thatthe concept of a functional ingredient derived from soybeans, which wasinspired by the wound healing system of living organisms, and newly acquired
data, have attracted so much interest. Please look forward to further researchin the future.” This study is the result of a research conducted using “NIKKOLLECINOL ® MFL*1,” a new product launched in 2023.

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<Research Summary>The number of people suffering from sensitive skin caused by atopic
dermatitis and stress, etc. is increased. According to “The prevalence ofsensitive skin”, 60-70% of women and 50-60% of men report having somedegree of sensitive skin on surveys conducted in 20 different countries in 5continents. One way to improve the sensitive skin is to increase the barriercomponent derived from keratinocytes that can help in maintaining the basal
skin parameter.
We are especially focused on lysophosphatidic acid, which is a type oflysophospholipid. This is because human originally uses it as a support system
for the skin barrier. We reported on the benefit to skin barrier of functional
lysolecithin, which was newly developed containing lysophosphatidic acid, using
in vitro and in vivo test at this conference. The functional lysolecithin induced
increase of the barrier related factors, epidermal-filaggrin and SC-ceramides, innormal human epidermal keratinocytes (NHEKs). In 0.1% functional lysolecithincream condition, the stratum corneum moisture content increased (+50%)
compared to the baseline. Furthermore, stinging-score decreased significantly
in 0.1% functional lysolecithin cream condition compared to the placebo creamcondition. These results indicated that functional lysolecithin promotes theimprovement of the sensitive skin through the regulation of epidermal barrier
maturation.
<Biographies of Award Winners>
Satoshi Yoshimoto

Education

Doctor of Philosophy in Engineering (May 2020)
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Graduate school of Okayama university of science
Experience

NIKKO CHEMICALS, Co., Ltd. (April 2020-present)

Specialty

Skin biology（photoaging・pigmentation）

In June 2023, Nikko Chemicals established a local subsidiary, Nikko Chemicals(India), in India, where this conference was held. We will continue to provide
high-quality cosmetic raw materials and technical support to the rapidly growing
Indian cosmetic market.
*1 NIKKOL LECINOL ® MFL
It is a multifunctional lysolecithin with high lysophosphatidic acid content,
which is increased through our unique enzymatic processing method. This
lysolecithin can be expected to accelerate the production of ceramide, a major
component of intercellular lipids, and filaggrin, a natural moisturizing factor. Inaddition, it is expected to promote the formation of tight junctions, which
comprehensively affects the strengthening of the skin barrier.

For inquiries:
Wakako Sone
Corporate Communications Division
Nikko Chemicals Co., Ltd.
1-4-8 Nihonbashi-Bakurocho, Chuoku, Tokyo 103-0002, Japan
E-mail: nk_corporate_communications@nikkolgroup.com

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