第 45 回 日本微小循環学会総会◆ 理事長講演日
演座
演時：9 月 4 日（金）13：30 ～ 14：10
題：日本微小循環学会の過去・現在・未来
長：荒木 信夫（よみうりランド慶友病院）
者：鈴木 秀和（東海大学医学部内科学系 消化器内科学）◆ 会長講演日演座
演時：9 月 5 日（土）11：40 ～ 12：10
題：Microbiome, Microcirculation and Medicine
長：松尾 雅斗（神奈川歯科大学大学院・口腔科学講座・歯科形態学分野）
者：内藤 裕二（京都府立医科大学大学院医学研究科 消化器内科学）◆ 特別講演＜特別講演 1 ＞
日
演
座
演

時：9 月 4 日（金）17：00 ～ 17：50
題：潰瘍性大腸炎における便細菌叢移植と腸内細菌叢の解析
長：内藤 裕二（京都府立医科大学大学院医学研究科 消化器内科学）者：飯田 宗穂（金沢大学附属病院 消化器内科）

第 6 回 Gut Microbiota 研究会・第 45 回日本微小循環学会総会

合同セッション

＜特別講演 2 ＞
日
演
座
演

時：9 月 4 日（金）17：50 ～ 18：40
題：イメージングメタボロミクスによるがんの代謝解析と医学応用
長：日比 紀文（北里大学北里研究所病院 炎症性腸疾患先進治療センター）者：末松誠（慶應義塾大学医学部 客員教授 医化学教室）

第 45 回日本微小循環学会総会・第 6 回 Gut Microbiota 研究会

合同セッション

＜特別講演 3 ＞
日
演
座
演

時：9 月 5 日（土）8：30 ～ 9：20
題：造血幹細胞と造血、骨を維持する骨髄の微小環境（ニッチ）長：岡田 英吉（富山市医師会健康管理センター病理部）
者：長澤 丘司（大阪大学大学院 生命機能研究科 / 医学系研究科・医学部）◆ 北島政樹先生追悼講演日
演
座
演時：9 月 5 日（土）14：00 ～ 14：50
題：北島政樹先生による微小循環学とその展開－鋳型法から蛍光ガイド手術の確立へ－
長：韓晶岩（北京大学医学部 中西医結合学）
者：吉田昌（国際医療福祉大学病院 外科）◆ 教育講演（モーニングセミナー）

12

日
演
座
演

時：9 月 5 日（土）8：00 ～ 8：30
題：脳微小血管の役割とその疾患
長：内藤 裕二（京都府立医科大学大学院医学研究科 消化器内科学）
者：水野 敏樹（京都府立医科大学大学院医学研究科 神経内科学）

共催：第一三共株式会社

The 45th Annual Meeting of Japanese Society for Microcirculation◆ シンポジウム＜シンポジウム 1基礎＞

日 時：9 月 4 日（金）14：50 ～ 16：50
テーマ：Microcirculation and Metabolism ～ Brainstorming technologies and ideas ～未来の微小循環学を駆動する新兵器と革新的概念
座 長：梶村 眞弓（慶應義塾大学 医学部 生物学教室）
福原 茂朋（日本医科大学 先端医学研究所 病態解析学部門）「チトクロム C オキシダーゼ活性調節による新規治療薬開発」
新谷 泰範（国立循環器病研究センター研究所 分子薬理部）「創傷治癒過程の血管新生において内腔圧は血管内皮細胞に伸展刺激を負荷することで血管伸長を制御する」
福原 茂朋（日本医科大学 先端医学研究所 病態解析学部門）「腸内細菌に介入する心血管病治療」
山下 智也（神戸大学医学部附属病院）「生体内でガス分子を操る多孔性材料の開発」
古川 修平（京都大学高等研究院 物質－細胞統合システム拠点）＜シンポジウム 2臨床＞

日 時：9 月 5 日（土）15：00 ～ 16：30
テーマ：Microcirculation and Pathophysiology
座 長：伊藤 義彰（大阪市立大学大学院医学研究科 脳神経内科学）
永田 博司（けいゆう病院 名誉院長）「骨格筋における微小循環障害と予防対策」
藤野 英己（神戸大学生命・医学系保健学域・神戸大学大学院保健学研究科）「眼底微小循環検査の進歩」
辻川 明孝（京都大学大学院医学研究科 眼科学）
「虚血再灌流傷害に対するプレ・ポストコンディショニング」
鎌田 和浩（京都府立医科大学大学院医学研究科 消化器内科学）◆ スポンサードセミナー＜スポンサードセミナー 1 ＞
日
演座
演

時：9 月 4 日（金）14：10 ～ 14：40
題：レーザー光内視鏡を用いた消化管腫瘍診断の最前線－微小血管構築像の診断を中心に－
長：穂苅 量太（防衛医科大学校 内科学（消化器））
者：土肥統（京都府立医科大学大学院医学研究科 消化器内科学）

共催：富士フイルム株式会社＜スポンサードセミナー 2 ＞
日
演座
演

時：9 月 5 日（土）12：20 ～ 13：10
題：消化管のマイグレーションとα 4 β 7 インテグリン製剤への期待
長：鈴木 秀和（東海大学医学部内科学系 消化器内科学）者：穂苅 量太（防衛医科大学校 内科学（消化器））

共

催：武田薬品工業株式会社

13

第 45 回 日本微小循環学会総会

PROGRAM
Friday, Septembar 4, 2020
Opening Remarks

13:25-13:30

President：Yuji Naito

Department of Gastroenterology and Hepatology, Kyoto Prefectural University of Medicine

Keynote LectureKL

13:30-14:10

The Japanese Society for Microcirculation: Past, Present & Future
Hidekazu Suzuki

Chair：Nobuo Araki

President of Japanese Society for Microcirculation,
Division of Gastroenterology and Hepatology, Department of Internal Medicine, Tokai University School of Medicine

Sponsored Seminar 1

14:10-14:40
Chair：Ryota Hokari

SS1 orefront of the endoscopic diagnosis using laser endoscopy for gastrointestinal tumors:F
focus on the diagnosis of microvascular architecture
Osamu Dohi
Department of Gastroenterology and Hepatology, Kyoto Prefectural University of Medicine

Sponsored by FUJIFILM corporation

Symposium 1Mic rocirculation and Metabolism～ Brainstorming technologies and ideas ～

14:50-16:50

Chair：Mayumi Kajimura
Shigetomo Fukuhara
SY1-1 Modulation of cytochrome c oxidase activity (CcO) is a novel therapeutic strategy
Yasunori Shintani
Department of Molecular Pharmacology, National Cerebral and Cardiovascular Center

SY1-2 Intraluminal pressure on injured blood vessels regulates wound angiogenesis
through mechanical stretching of endothelial cells
Shigetomo Fukuhara
Department of Molecular Pathophysiology, Institutes of Advanced Sciences, Nippon Medical School

SY1-3 Alteration of gut microbiota could be a novel therapeutic strategy
for preventing cardiovascular diseases
Tomoya Yamashita
Kobe University Hospital

SY1-4 Porous materials for controlling bioactive gases
Shuhei Furukawa
Institute for Integrated Cell-Material Sciences, Kyoto University

Special Lecture 1
SL1

17:00-17:50

Chair：Yuji Naito
Analysis of gut microbiota post fecal microbiota transplantation in patients of ulcerative colitis
Noriho Iida
Department of Gastroenterology, Kanazawa University Hospital

Joint Session：The 6th Gut Microbiota Research Society,The 45th Annual Meeting of Japanese Society for Microcirculation

Special Lecture 2
SL216Imaging metabolomics for dissecting cancer metabolism
Makoto Suematsu

Department of Biochemistry, Keio University School of Medicine
Joint Session：The 45th Annual Meeting of Japanese Society for Microcirculation,
The 6th Gut Microbiota Research Society

17:50-18:40
Chair：Toshifumi Hibi

The 45th Annual Meeting of Japanese Society for Microcirculation

Saturday, Septembar 5, 2020
Educational Lecture（Morning Seminar）
EL

8:00-8:30
Chair：Yuji Naito

A role of cerebral small vessel and it’s pathological stateToshiki Mizuno
Department of Neurology, Kyoto Prefectural University of Medicine

Sponsored by DAIICHISANKYO COMPANY, LIMITED

Special Lecture 3
SL3

8:30-9:20

Chair：Eikichi Okada
Bone marrow microenvironmental niches for hematopoietic stem cells and hematopoiesis
Takashi Nagasawa
Graduate School of Frontier Biosciences, Graduate School of Medicine, Osaka University

Applicants' Presentation for Young Investigator Award
Y-01

9:20-10:20

Chair：Toyotaka Yada
Masahiko Nakamura
Platelet-rich fibrin application promotes vascularization and osteogenic differentiationin periodontal tissue
Masahiro To, Satoko Wada-Takahashi, Shun-suke Takahashi, Masato Matsuo

Department of Oral Science, Graduate School of Dentistry, Kanagawa Dental University

Y-02

Indigo Naturalis increases ILC3 flowingthrough mesenteric lymphatic vasculaturefrom intestinal mucosa
Rina Tanemoto, Kazuki Horiuchi, Masaaki Higashiyama, Ryota Hokari
Department of Internal medicine, National Defense Medical College

Y-03

 LRP3 Inflammasome-derived interleukin-1β attenuates stress-induced gastric injury
Nvia the COX-2/PGE2 axis
Akira Higashimori, Toshio Watanabe, Yuji Nadatani, Koji Otani, Tetsuya Tanigawa, Yasuhiro Fujiwara
Department of gastroenterology, Osaka City University Graduate school of Medicine

Y-04

NLRP3 inflammasome-mediated caspase-1 activation prevents gastric mucosal healing
Yuji Nadatani1,2）, Toshio Watanabe2）, Akira Higashimori2）, Koji Otani2）, Tetsuya Tanigawa2）
1）Department of premier preventive medicine, Osaka city University Graduate school of Medicine2）Department of gastroenterology, Osaka City University Graduate school of Medicine

Free Paper 1

10:30-11:40
Chair：Kazuto Masamoto
Takanori Yasu

F-01

 ptogenetic manipulation of cerebral microcirculation by transcranial photostimulation toO
the channelrhodopsin-2 expressing mouse brains
Juri Murata1）, Miyuki Unekawa2）, Iwao Kanno3）, Yutaka Tomita2,4）,Kenji F. Tanaka5）, Jin Nakahara2）, Kazuto Masamoto1,6）1）Department of Mechanical Engineering and Intelligent Systems, University of Electro-Communications2）Department of Neurology, Keio University School of Medicine
3）Department of Functional Brain Imaging Research, National Institute of Radiological Sciences
4）Tomita Hospital5）Department of Neuropsychiatry, Keio University School of Medicine
6）Center for Neuroscience and Biomedical Engineering, University of Electro-Communications

F-02 ynamic response of arterial diameter and red blood cell velocity in capillaries associatedDwith cortical spreading depolarization/depression
Chunhua Tang1), Miyuki Unekawa1）, Yutaka Tomita1）, Kazuto Masamoto2）,
Iwao Kanno3）, Jin Nakahara1）

1）Department of Neurology, Keio University School of Medicine2）Brain Science Inspired Life Support Research Center, University of Electro-Communications3）Department of Functional Brain Imaging Research, National Institute of Radiological Sciences17

第 45 回 日本微小循環学会総会
F-03

F
 low Velocity Mapping of the Human Nailfold Microcirculation Imaged with Capillary Flow VideoMicroscopyTomoya Niizawa1）, Takuma Sugashi1）, Tomoya Kusaka1）, Ichiro Miura2,3,4）, Keiji Kawagoe 4,5）,
Kazuto Masamoto1,6）1）Graduate School of Informatics and Engineering, University of Electro-Communications2）Department of Clinical Laboratory, Obihiro Kyokai General Hospital3）Department of Human Pathology, School of Medicine, Juntendo University4）NPO Mousaikekkan Kenkyukai (Japanese Capillary Research Conference）
5）Toku Corporation
6）Center for Neuroscience and Biomedical Engineering, University of Electro-Communications

F-04

Effects of Life Style Differences on the Human Nailfold Microcirculation

Tomoya Kusaka1）, Takuma Sugashi1）, Tomoya Niizawa1）, Ichiro Miura2,3,4）, Keiji Kawagoe4,5）,
Kazuto Masamoto1,6）1）Graduate School of Informatics and Engineering, University of Electro-Communications2）Department of Clinical Laboratory, Obihiro Kyokai General Hospital3）Department of Human Pathology, School of Medicine, Juntendo University4）NPO Mousaikekkan Kenkyukai（Japanese Capillary Research Conference）
5）Toku Corporation
6）Center for Neuroscience and Biomedical Engineering, University of Electro-Communications

F-05

 ffect of the infrared rays given to the neck on the capillary blood flow rate of the finger:
Evideo motion analysis
Wasa Ueda1）, Michio Aoki2）, Shigeo Ogasawara3）
1）Kochi University2）Aoki Neurosurgery and Plastic Surgery Hospital3）Kochi High Power Senka

F-06

A ge-related changes in the facial skin blood flow in healthy women examined by laser
speckle flowgraphy
Yoshinao Nagashima1,2,3）, Yuko Ohsugi1,3）, Yoshifumi Niki1）, Akira Fuji1）, Takashi Okamoto2）,
Masataka Majima3）
1）Personal Health Care Products Research, Kao Corporation2）Department of Systems Design and Informatics, Kyushu Institute of Technology
3）Kitasato University, School of Medicine

F-07Spatiotemporal Correlation Analysis of the Capillary Red Blood Cell Flow and Vessel
Diameters in the Anesthetized Rat Cortex
Ruka Sakuraba1）, Tomoya Kusaka1）, Takuma Sugashi1）, Kazuto Masamoto1,2）1）Department of Mechanical Engineering and Intelligent Systems, University of Electro-Communications2） Center for Neuroscience and Biomedical Engineering, University of Electro-Communications

Presidential LecturePL

11:40-12:10
Chair：Masato Matsuo

Microbiome, Microcirculation and Medicine
Yuji Naito

Department of Gastroenterology and Hepatology, Kyoto Prefectural University of Medicine

Sponsored Seminar 2
SS2

12:20-13:10

Chair：Hidekazu SuzukiM igration of the digestive tract and expectation of the α4β7 integrin preparationin Ulcerative Colitis
Ryota Hokari
Gastroenterology Director, Department of Internal Medicine, National Defense Medical College

Sponsored by Takeda Pharmaceutical Company Limited

Council Meeting and General Assembly

13:20-14:00

Memorial Lecture～ Remembrance of Prof. Masaki Kitajima ～

14:00-14:50

ML

18

Chair：Jing-Yan Han
 xpansion of Prof. Masaki Kitajima’s achievements on the field of the microcirculation
E－ From silicon rubber cast to the developments of the fluorescence guided surgery －Masashi Yoshida
Department of Surgery, International University of Health and Welfare Hospital

The 45th Annual Meeting of Japanese Society for Microcirculation

Symposium 2
Microcirculation and Pathophysiology

15:00-16:30

Organizer：Yoshiaki Ito
Hiroshi Nagata
SY2-1 Therapeutic countermeasures to attenuate microcirculation disorders in skeletal muscle
Hidemi Fujino
Kobe University Graduate School of Health Sciences

SY2-2 Evolution of Examination Devices for Human Retinal Microcirculation
Akitaka Tsujikawa

Department of Ophthalmology and Visual Sciences, Kyoto University Graduate School of Medicine

SY2-3 Effect of pre and postconditioning on ischemic/reperfusion injury
Kazuhiro Kamada, Yuji Naito

Department of Gastroenterology and Hepatology, Kyoto Prefectural University of Medicine

Free Paper 2
F-08

16:30-17:30

Chair：Toshihiro Nishizawa
Toshio Watanabe
Intercellular transport of Amyloid β in vivo Observed with Multiphoton Microscopy
Itsuki Hasegawa, Norie Kimura, Shinobu Minatani, Takato Abe, Yoshiaki Itoh
Department of Neurology, Osaka City University Graduate School of Medicine

F-09 orphologic Classifications and Locations of Microaneurysms and Clinical Relevance
Min Branch Retinal Vein Occlusion
Yuya Esaki, Yoshio Hirano, Yuichiro Ogura

Department of Ophthalmology & Visual Science, Nagoya City University Graduate School of Medical Sciences

F-10

Immunohistochemical observation of the microvasculature of the human mammary tissue
Eikichi Okada

Department of Pathology, Toyama City Medical Association Health Control Center

F-11

Translocation Route of bacteria detected in liver and lung in the Helicobacter suis infected mouse
Masahiko Nakamura1）, Hidekazu Suzuki2）

1）School of Pharmacy, Kitasato University2）Department of Gastroenterology and Hepatology, Tokai University School of Medicine

F-12T
 he effects of a new carbon monoxide (CO)-releasing molecule (CORM401) inmicrocirculation
Ken Inoue1）, Gediminas Cepinskas2）, Kazuhiro Kamada1）, Kazuhiro Katada1）,
Kazuhiko Uchiyama1）, Takeshi Ishikawa1）, Tomohisa Takagi1）, Yuji Naito1）, Yoshito Itoh1）
1）Department of Gastroenterology and Hepatology, Kyoto Prefectural University of Medicine
2）Centre for Critical Illness Research, LHRI

F-13

 angXue QingNao Wan, a Compound Chinese Medicine, Attenuates CerebrovascularY
Hyperpermeability and Neuron Injury in Spontaneously Hypertensive Rat
Jing-Yan Han1,2）1）Department of Integration of Chinese and Western Medicine, School of Basic Medical Sciences, Peking University2）Tasly Microcirculation Research Center, Peking University Health Science Center

Awards ceremony

17:30-17:40

Closing Remarks

17:40-17:50

President：Yuji Naito

Department of Gastroenterology and Hepatology, Kyoto Prefectural University of Medicine

19