Program
Day 1, Saturday, April 8
11:25 - 11:30

Room 1

Opening Remarks
ACRI 2023 President：Hiroaki Shibahara
Department of Obstetrics and Gynecology, School of Medicine, Hyogo
Medical University

11:30 - 12:00

Opening Lecture
Chair：Tadashi Kimura
Obstetrics and Gynecology, Department of Organ Regulation Medicine, Graduate School ofMedicne, Faculty of Medicine, Osaka University

OL

Decreased paternal/fetal antigen-specific Treg cells are involved inthe pathogenesis of preeclampsia, and decreased Treg cells pool areinvolved in the pathogenesis of miscarriage
Shigeru Saito
University of Toyama

12:10 - 13:10

Luncheon Seminar 1：PGT-A
Sponsored by: Setouchi Society for Assisted Reproductive Technology
Chair：Mikiya Nakatsuka
Graduate School of Health Sciences, Okayama University

LS1-1

PGT-A, past, present, and future in Japan
Takeshi Iwasa
Department of Obstetrics and Gynecology,Tokushima University Graduate School of BiomedicalSciences

LS1-2

Our strategy to maximize clinical PGT programTetsunori Mukaida
Hiroshima HART Clinic

13:15 - 14:35

Symposium 1：Endometriosis
Chairs：Takashi Murakami
Department of Obstetrics and Gynecology, Shiga University of Medical Science
Kaori Koga
Department of Obstetrics and Gynecology, Graduate School of Medicine Chiba University

S1-1

The peritoneal immune environment in the pathogenesis of endometriosis
Kaori Koga
Department of Obstetrics and Gynecology, Graduate School of Medicine Chiba University

S1-2

NK cell abnormalities and endometriosis
Ayano Yamaya
Department of Obstetrics and Gynecology, School of Medicine, Hyogo Medical University

15

S1-3

Infection and Inflammation in the Pathogenesis of Endometriosis
Ae Ra Han
CHA University Fertility Center Daegu

14:35 - 14:50

Coffee Break: Outside Room 1 (301)

14:50 - 15:50

Special Lecture 1Chair：Hideto Yamada
Center for Recurrent Pregnancy Loss, Teine Keijinkai Hospital

SL1

Immunotherapy for reproductive failure women in Korea: present andfuture
Sung Ki Lee
Department of Obstetrics and Gynecology, Konyang University College of Medicine

15:55 - 16:35

Special Lecture 2
Chair：Tomohiko Wakayama
Department of Histology, Faculty of Life Sciences, Kumamoto University

SL2

Testis-enriched genes and their functions for spermatogenesis andfertilization
Masahito Ikawa
Department of Experimental Genome Research, Genome Information Research Center, ResearchInstitute for Microbial Diseases, Osaka University

16:40 - 17:40

Special Lecture 3
Chair：Tomoyuki Fujii
Sanno Hospital

SL3Placental-microbial interactions; Possible roles of endometrial commensals
in trophoblast invasion and placental barrier against pathogenic viruses
Satoshi Hayakawa
Division of Microbiology Department of Pathology and Microbiology, Nihon University School ofMedicine

16Day 1, Saturday, April 8
13:30 - 14:06

Room 2

Oral 1：Recurrent Pregnancy Loss-1
Chair：Masashi Deguchi
Department of Obstetrics and Gynecology, Kobe University Graduate School of Medicine

O1-1

Clinical efficacy of low-molecular-weight heparin plus aspirin versus
aspirin alone in repeat pregnancy loss women with thrombotic causes
Joon Cheol Park
Department of Obstetrics and Gynecology, School of Medicine, Kyungpook National University

O1-2

A case of severe fetal growth restriction with oligohydramnios wassuccessfully treated with antithrombotic therapy
Tomoko Ichikawa
Department of Obstetrics and Gynecology, Nippon Medical School

O1-3

AREG+ NK cell accelerates decidualization by interacting with IGF1+
stromal cell
Jia-Wei Shi
NHC Key Lab of Reproduction Regulation, Hospital of Obstetrics and Gynecology, Shanghai Institutefor Biomedical and Pharmaceutical Technologies, Fudan University

14:06 - 15:06

Oral 2：Recurrent Pregnancy Loss-2
Chair：Atsushi Fukui
Department of Obstetrics and Gynecology, School of Medicine, Hyogo Medical University

O2-1

Dysfunction of CCR1+ Decidual Macrophages is a Potential Risk Factor
in the Occurrence of Unexplained Recurrent Pregnancy LossYifei Sang
Hospital of Obstetrics & Gynecology, Fudan UniversityO2-2

Role of PROK1 in decidua of patients with unexplained recurrent
pregnancy loss showing insulin hypersecretion
Shinobu Goto
Department of Obstetrics and Gynecology, Nagoya City University Graduate School of MedicalScienceO2-3

Obesity Challenge Drives Distinct Maternal Immune Response Changes
in Normal Pregnant and Abortion Prone Mouse Models
Yanhong Li
Hospital of Obstetrics & Gynecology, Fudan University

O2-4

LPA promotes the autophagy of trophoblast cells in early pregnancy
Jun Shao

Hospital of Obstetrics & Gynecology, Fudan University

O2-5

Expression of cell adhesion molecules on peripheral blood NK cells inrecurrent pregnancy losses
Ayano Yamaya
Department of Obstetrics and Gynecology, School of Medicine, Hyogo Medical University17

15:06 - 15:54

Oral 3：Endometrium and Embryo
Chair：Koji Nakagawa
Sugiyama Clinic Shinjuku

O3-1Risk factors for chronic endometritis in infertile women with intrauterine
disorders after hysteroscopic surgery
Keiji Kuroda
Sugiyama Clinic Shinjuku, Center for Reproductive Medicine and Endoscopy

O3-2Abnormalities in the endometrial microbiota may affect pregnancy
outcomes of assisted reproductive technology.
Motowo Nabeta
Tsubaki Women's Clinic

O3-3

Bioinformatics Analysis Identifies Potential Biomarkers and Immune
Infiltration Characteristics in Recurrent Implantation Failure
Zhen-zhen Lai
NHC Key Lab of Reproduction Regulation, Hospital of Obstetrics and Gynecology, Shanghai Institutefor Biomedical and Pharmaceutical Technologies, Fudan University

O3-4

Effects of conditioned media from polarized macrophages on mouse
pre-implantation embryonic development and outgrowth of blastocysts
Jin Hyun Jun
Department of Biomedical Laboratory Science, Graduate School, Eulji University

15:54 - 16:42

Oral 4：Repeated Implantation Failure
Chair：Fuminori Kimura
Department of Obstetrics and Gynecology, Nara Medical University

O4-1

Evaluation of the tacrolimus treatment using euploid blastocyst forwomen with repeated implantation failures showing elevated type-1
helper T (Th1)/Th2 cell ratios
Koji Nakagawa
Sugiyama Clinic Shinjuku

O4-2

The distribution of serum Th1/2 ratio and NK cell activity in patientswith recurrent implantation failure
Yihsien Enatsu
Hanabusa Women's Clinic

O4-3

Evidence for Correlation between Novel Autoantibody against
Phospholipid Named Neoself Antibody (β2GPI/HLA-DR) and Complement
Consumption in Infertile Patients
Hirotaka Matsumi
Matsumi Ladies Clinic Mita

O4-4

Does intrauterine infusion of PRP affect the window of implantation?
Kunihiro Enatsu

Hanabusa Women's Clinic Nishinomiya

1816:42 - 17:30

Oral 5：Preeclampsia and Placenta
Chair：Akihide Ohkuchi
Department of Obstetrics and Gynecology, Jichi Medical University

O5-1

Development of an in vitro preeclampsia model in the villous tissue
using an autophagy inhibitor, Bafilomycin
Atsushi Furuta
Department of Obstetrics and Gynecology, University of Toyama

O5-2

The advanced possibility of pravastatin in advanced maternal aged
pregnancy complicated preeclampsia
Risa Miyatake
Obstetrics and Gynecology, Faculty of Medicine, the University of Tokyo

O5-3

IL-18 induces proper inflammation contributing placental development
and fetal growth
Hajime InoDepartment of Obstetrics and Gynecology, Nippon Medical School

O5-4

Trophoblast cell line BeWo cell-derived nanoparticles contain a large
amount of placenta-specific microRNAs and modify the gene expressionof recipient immune cells (T lymphocyte cell line Jurkat cells)
Syunya Noguchi
Department of Molecular Medicine and Anatomy, Nippon Medical School

18:00 - 20:00

Gala Dinner：Banquet Hall Kairaku, B1F, Main Building, Kobe Portopia
Hotel19