Program
Tuesday, June 25
9:00

Registration

Opening Remarks:
10:00
Kazuhiko YAMAMOTO, Director, RIKEN IMS
Session I:

GUT IMMUNITY

Chairs: K. MORO and R. XAVIER

10:10

I-1

Naoko SATOH-TAKAYAMA, RIKEN IMS (Japan)
Innate lymphoid cells with a unique role in the regulation of peritonitis.

10:40

I-2

Ramnik XAVIER, The Broad Institute of MIT & Harvard (USA)
Learning Mucosal Immunity from Human Genetics

11:10

I-3

Ye-Ji BANG, Seoul National University College of Medicine (South Korea)
Bacterial regulation of vitamin A transport and its role in the intestinal immunity

11:40

I-4

Kazuyo MORO, RIKEN IMS (Japan)
The Impact of Appendectomy on Ulcerative Colitis

12:10

LunchSession II:

RNA BIOLOGY IN IMMUNITY

13:40 II-1

Sun HUR, HHMI and Harvard Medical School (USA)
Nucleic acid-driven self-assemblies: FoxP3 and Aire

14:10 II-2

Manolis PASPARAKIS, University of Cologne (Germany)
Regulation and sensing of self Z-RNA in cell death and interferon responses

14:40 II-3

Hiroki KATO, University of Bonn (Germany)
Dysregulation of Treg homeostasis by ADAR1 deficiency and chronic MDA5 signaling

15:10

Coffee Break

15:40 II-4

Yuka W. IWASAKI, RIKEN IMS (Japan)
Small RNA-mediated genome defense from transposable elements

16:10 II-5

Osamu Takeuchi, Graduate School of Medicine, Kyoto University (Japan)
Post-transcriptional regulation of the immune system by Regnase-1-relatedendoribonucleases

Chairs: O. TAKEUCHI and S. HUR

JSI Young Investigator Awardee:
16:40 II-6 Daichi YAMASOBA, Kobe University School of Medicine (JAPAN)
N4BP1 restricts HIV-1 and its inactivation by MALT1 promotes viral reactivation
JSI Young Investigator Awardee:
17:00 II-7 Saya MORIYAMA, National Institute of Infectious Diseases (Japan)
Broadly neutralizing antibodies against SARS-CoV-2
IMS Young Investigator Talk:
17:20 II-8 Takuma MISAWA, RIKEN IMS (Japan)
Innate lymphoid cells rewire ketogenesis by promoting lipid transports through the portalvein.
17:40

End of the dayWednesday, June 26
9:00

Registration

Session III:BEHAVIOUR & IMMUNOLOGY

9:30

III-1

Takaharu OKADA, RIKEN IMS (Japan)
Multiple types of sensory neurons responsible for atopic dermatitis itch

10:00

III-2 Anna Victoria MOLOFSKY, University of California, San Francisco (USA)
Cytokine regulation of brain development

10:30
10:50

Chairs: T. OKADA and A. MOLOFSKY

Coffee BreakIII-3 Hans-Reimer RODEWALD, German Cancer Research Center (Germany)
Mast cells and immunity of avoidance

JSI Young Investigator Awardee
11:20 III-4 Baihao ZHANG, RIKEN IMS (JAPAN)
B cell-derived GABA elicits anti-inflammatory macrophages limiting anti-tumour cytotoxic
responses
11:40 III-5 Yukinori OKADA, RIKEN IMS/The University of Tokyo/Osaka University (JAPAN)
Statistical genetics elucidates biology and medicine of immune-related diseases
12:10Lunch

Session IV:

MULTI-OMICS ANALYSIS

Chairs: K. ISHIGAKI and G. TRYNKA

13:40

IV-1 Gosia TRYNKA, Wellcome Sanger Institute (UK)
From GWAS to function: interrogating biology at scale to contextualise gene function

14:10

IV-2 Keisuke GODA, Department of Chemistry, The University of Tokyo (Japan)
Intelligent image-activated cell sorting

Publisher Talk
14:40
Montserrat COLS VIDAL Journal of Experimental Medicine, Senior Scientific Editor (USA)
Scientific publishing at JEM: What, How and Why
15:05

Coffee BreakSession V:IMMUNODEFICIENCY & GENE THERAPY

Chairs: I. TANIUCHI and G. CROOKSIMS Young Investigator Talk:
15:40 V-1 Kazuki OKUYAMA, RIKEN IMS (Japan)
Interference of Bcl11a-Bcl11b heterodimer function by BCL11B N441K variant during
neurogenesis and early T cell development
16:00

V-2 Gay M. CROOKS, University of California, Los Angeles (USA)
Adenine Base Editing of Human Hematopoietic Stem Cells for Correction of CD3D Severe
Combined Immune Deficiency

16:30 V-3 Satoshi YAMAZAKI, The Institute of Medical Science, The University of Tokyo (Japan)
Expansion hematopoietic stem cells and application
17:00 V-4 Boyoung SHIN, California Institute of Technology (USA)
Dissecting environmental and transcription factor inputs that convert multipotent bonemarrow progenitor cells into early T-progenitor cells using a new in vitro system

Closing Remarks:
17:20
Tomohiro KUROSAKI, President, Japanese Society for Immunology
17:25

End of the day

18:00

Social Gathering