Program
Thursday, June 29
9:00

Registration

Opening Remarks:
10:00
Kazuhiko YAMAMOTO, Director, RIKEN IMS
Session I: IMMUNE MEMORY

Chairs: L. MACKAY and K. ISHII

10:10

I-1

Hai-Hui XUE, Hackensack University Medical Center (USA)
3D genome reorganization underlies enhanced recall capacity by central memory CD8+ Tcells

10:40

I-2

Shin-ichiro FUJII, RIKEN IMS/RIKEN DMP (Japan)
Therapeutic vaccine eliciting multifunctional immunity, artificial adjuvant vector cells (aAVC)

11:10

Coffee Break

11:30

I-3

Laura MACKAY, Peter Doherty Institute at the University of Melbourne (Australia)
Deconvoluting tissue-resident memory T cells in tumours

12:00

I-4

Sho YAMASAKI, RIMD, IFReC, Osaka University (Japan)
Deciphering clonotypic responses of human T cells against infection

12:30

Lunch

14:00

I-5

Ken ISHII, The Institute of Medical Science, The University of Tokyo (Japan)
Extracellular nucleic acids and their metabolite in immunity and vaccine science

14:30

I-6

Andrea ABLASSER, Global Health Institute, EPFL (Switzerland)
Sensing DNA as a danger signal through the cGAS-STING pathway

15:00

Coffee BreakSession II:AGE-RELATED IMMUNE RESPONSE

15:20 II-1

Yoko HAMAZAKI, Center for iPS Cell Research and Application, Kyoto University (Japan)
TBD

15:50 II-2

Kenya HONDA, RIKEN IMS/Keio University School of Medicine (Japan)
Toward development of defined microbial therapeutics

16:20 II-3

Eiji HARA, RIMD, Osaka University (Japan)
The role of cellular senescence in aging and cancer: a gut microbial connection

16:50 II-4

Michelle LINTERMAN, Babraham Institute (UK)Lost in space: How ageing causes helper T cells to lose their way

Chairs: K. HONDA and M. LINTERMAN

Young Speaker from RIKEN IMS 1:
17:20
Tetsuro KOBAYASHI, RIKEN IMS (Japan)
Innate lymphoid cells promote skin barrier repair after mechanical damage
17:40

End of the day

Friday, June 30
9:00
Session III:Registration
IMMUNOMETABOLISM

Chairs: S. FAGARASAN and M. ARITA

9:30 III-1 Sidonia FAGARASAN, RIKEN IMS (Japan)
A novel B cell-derived metabolite elicits anti-inflammatory macrophages and limits
anti-tumor cytotoxic responses
10:00 III-2 Behdad AFZALI, National Institute of Diabetes and Digestive and Kidney Diseases, NIH (USA)Transcription factors regulating T cell inflammation
10:30

Coffee Break

10:50 III-3 Yusuke ENDO, KAZUSA DNA Research Institute (Japan)
The novel function of lipid synthetic flux on Th17 cell differentiation and pathogenicity
Session IV:

REGULATION OF INFLAMMATION

Chairs: K. ISHIGAKI and H. NAMKOONG

11:20 IV-1 Soumya RAYCHAUDHURI, Brigham and Women’s Hospital, Harvard Medical School,
Broad Institute (USA)Defining mechanisms of autoimmune diseases with genetics and single cell genomics
JSI Young Investigator Awardee 1:
11:50
Sho HANGAI, Herbert Irving Comprehensive Cancer Center, Columbia University (USA)
TCTP released by tumor cells orchestrates dynamics of myeloid-derived suppressor cells
in the tumor immune microenvironment
12:10Lunch

13:30 IV-2 Kazuyoshi ISHIGAKI, RIKEN IMS (Japan)
T cell receptor patterns critical for T cell fate determination and autoimmunity risk
14:00 IV-3 Yumi MATSUOKA-NAKAMURA, IFReC, Osaka University (Japan)
Impact of staphylococcus Agr quorum sensing in atopic dermatitis and systemic infection
14:30 IV-4 Daisuke SUGIURA, Institute for Quantitative Biosciences, The University of Tokyo (Japan)
Regulation of T cell activation by cis-PD-L1–CD80 interactions
15:00

Coffee Break15:20 IV-5 Ho NAMKOONG, Keio University School of Medicine (Japan)
DOCK2 is involved in the host genetics and biology of severe COVID-19
15:50 IV-6 Chrysothemis BROWN, Memorial Sloan Kettering Cancer Center (USA)
Early life imprinting of intestinal tolerance
Session V:

Chair: I.TANIUCHIJSI Young Investigator Awardee 2:
16:20
Takeshi KAWABE, Tohoku University Graduate School of Medicine (Japan)
Self-driven memory-phenotype cells: a naturally arising CD4+ T lymphocyte population
possessing innate immune function
Young speaker from RIKEN IMS 2:
16:40
Motoi YAMASHITA, RIKEN IMS (Japan)
Chemical-induced degradation of immune proteins in mice by degron systems
Publisher Talk Laurie DEMPSEY, Nature Immunology editor (USA)
17:00
Demystifying the publishing process at Nature journals – Insights from 20+ years as a
Nature Immunology editor
Closing Remarks:
17:20
Kohei MIYAZONO, Executive Director, RIKEN
17:30

End of the day

18:00

Social Gathering