TOHO HOLDINGS CO.,LTD.
Head Office			
Establishment 		
Capital			
Stock Listings		
Representative			
Number of Employees		
Main Banks
		
			
			

Tokyo Midtown Yaesu, Yaesu Central Tower 9F
2-2-1, Yaesu, Chuo-ku, Tokyo 104-0028, Japan
September 17,1948
10,649 million yen
Tokyo Stock Exchange, Prime Market（Stock Code: 8129 ）Hiromi Edahiro, Representative Director, CEO and CFO
7,572 (Consolidated)
Mizuho Bank, Ltd.
MUFG Bank, Ltd.
Sumitomo Mitsui Banking Corporation

https://www.tohohd.co.jp/en

Company Profile

Total commitment to good healthTop Message

Vision Statement

Total commitment to good healthCorporate Slogan

We, TOHO HOLDINGS CO., LTD. and its group companies, conduct pharmaceutical wholesaling,
dispensing pharmacy, pharmaceutical manufacturing and sales, and other businesses as a corporategroup engaged in the medical, health-care, and nursing care industries. Since our founding, we havebeen endeavoring to create social value through medical and health-care services.
In Japan, the government is currently promoting health-care cost reduction policies with a view tobuilding and maintaining a sustainable social security system amid lengthening healthy life expectancyof the population, the super-aging society, and a declining total population. At the same time,
guidelines are being issued and systems are being reformed to solve various problems pertaining topharmaceutical distribution. In addition, specialty pharmaceuticals, such as biomedical products andregenerative medical products, are being developed actively, bringing about major changes topharmaceutical distribution. Furthermore, drastic changes in people’s lifestyles brought about by the
COVID-19 pandemic have accelerated the restructuring of the health-care delivery system, including
the introduction of online medical services as a means to ease concerns about the infectious disease.
Surrounded by this industry environment, we will quickly and properly respond to social changes andchallenges and contribute to enriching people’s lives, by supplying health-care-related products such asprescription pharmaceuticals in a stable manner and providing the Company’s unique customer support
systems based on the solid business infrastructure and cutting-edge distribution centers we havedeveloped over the years.
Also, in a bid to achieve sustainable corporate growth and increase corporate value over the medium
to long term, we are working to reduce the effects on the environment by changing our businessactivities such as optimizing the delivery frequency; to nurture a diverse corporate culture by utilizing
a wide array of human resources regardless of gender, nationality, etc.; to strengthen governance toconduct sound business activities; and to takecountermeasures against earthquake and pandemic toensure a stable supply of pharmaceuticals. Throughthese measures, we are determined to make a greater
contribution than ever to all of our stakeholders.
We m u s t t r a n s f o r m o u r s e l v e s i n t o a n e w
pharmaceutical distribution company to keep up withthe changing times. Under the corporate slogan of“Total commitment to good health,” we will continue
to evolve and grow, aiming to be a company that iscontinuously supported by all stakeholders.

“Total commitment to good health” is Toho Holdings’s pledge, representing our philosophy of constantly giving toppriority to people who wish good health and creating customer value to raise their levels of satisfaction, andrepresenting our desire to contribute to the broad enhancement of people’s health and to them realizing
comfortable lifestyles.

TOHO HOLDINGS CO., LTD.
Representative Director, CEO and CFO

Hiromi Edahiro
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TOHO HOLDINGS CO., LTD. / Company profile"Total commitment to good health"Mission Statement"We shall live in harmony with society and our customers; together, we shall create new values through theprovision of original service; and we shall contribute to the medical care and well-being of people around theworld."

Core Values～Five “trust and sympathy”
Trust & Sympathy
with People who wish good healthWe put people who wish good health first all the time andact in the interests of enhancing their satisfaction.

Trust & Sympathy
with Customers
We strive our utmost every day to be
a company essential to our customers.

Trust & Sympathy
with Employees
We respect the personality, talent, andteamwork of all members, and value a
corporate culture that is free andvigorous.

Trust & Sympathy
with Society
We observe laws and ethics, and strive togrow in harmony with society and for the
benefit of its development.

Trust & Sympathy
with Shareholders
We pursue ever-greater corporate value andchampion timely and adequate disclosure.

Business Domain (Business Structure Vision)
FIELD

Medical care,Health,Comfortable lifestyle
Expand presence in health-related sectors around medical care, with theprescription pharmaceuticals wholesale business as the core business.

STAGE

Japan & the World
Cover Japan nationwide, and survey expansion overseas.

STRATEGY

Sizebased competition→Business model-based competition
Create numerous customer-value-creation business models
with an alliance base that transcends industry borders.

TOHO HOLDINGS CO., LTD. / Company Profile

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About TOHO HOLDINGSCreate our future together
Total commitment to good healthPharmaceutical wholesaling

Deliver pharmaceuticals in an accurate, secure and safe manner, anytime, anywhere. It is our mission,
supporting pharmaceutical distribution nationwide. While visiting medical institutions on a daily basis, we
also provide support for creating the better medical care environment. Supporting medical care means to
support people’s lives.
As the center of the Kyoso Mirai Group, the TOHO HOLDINGS is committed to building the better future
together with you.

Looking ahead towards a new era, we pledge to center ourefforts on frontier operations, such as customer support
systems contributing to higher business efficiency,
assistance in the start-up of medical institutions andpharmacies, management consulting services, total medical
support by transferring pharmacists and registered dietitians
to medical institutions and personnel recruitment, based
mainly on wholesaling business for pharmaceuticals,
reagents, medical equipment and OTC drugs.

Dispensing pharmacy
Phrmaceutical wholesaling
Customer support system
Manufacturing and sales ofpharmaceuticals and others

Dispensing Pharmacy

Other（Information processing, SMO,
Medical management consulting, etc.）

Kyoso Mirai Groupin Pharmacy

Manufacturing and sales ofpharmaceuticals and others

Business infrastructure

Highly functional logistics

Real-time inventory management
System redundancy

Wide-area disaster transport base
Automation rate:95%
Complies with Good Distribution Practice (GDP) Guidelines
Specialty and Orphan medicinal products Distribution

Mechanisms supporting the business modelthat focuses on value-added services

TOHO HOLDINGSGroup structure

TOHO HOLDINGS(business management, planning, administration)

Pharmaceutical wholesaling

Dispensing pharmacy

Toho PharmaceuticalPharmaCluster

SAYWELL
Koyo
Kyushu Toho
Okinawa Toho
Sakai Yakuhin
and others

PHARMA MIRAIVEGA PHARMAJ.MIRAIMEDICALAOBADOKOSEISEIKO MEDICAL BRAIN
PHARMA DAIWA
and others

Manufacturing and sales ofpharmaceuticals and others

KYOSOMIRAI PHARMA
Sunmedical
and others

We aim to serve as a trusted group of home pharmacies
and pharmacists that contribute to local healthcare andsociety. In addition to dispensing and providing medication
guidance, we are making active efforts, as a community
health-care support pharmacy, to respond to recent changes
in the health-care delivery system by providing home
medical care, selling OTC drugs, operating cafes fordementia patients, strengthening advanced pharmaceuticalmanagement functions, etc.

OthersTokyo Research Center ofClinical Pharmacology
Toho Systems Service
ALF
Nextit Research Institute
eKenkoshop Corporation
eHealthcare
Orphan Trust Japan
Hubei Kyoso Pharmaceutical
Kokando and Kyoso Mirai Asia
Toho Real Estate
Alpharia
enTouchand others

We manufactures and sell generic drugs and contract
manufacturing of injectable pharmaceuticals. We verify andg u a ra nte e q u a l i t y b a s e d o n o u r k n o w l e d ge a s apharmaceutical wholesaler and ensure a stable andcontinuous supply of high-quality generic drugs. We also
strive to disclose information on API manufacturing
countries and names of drug makers and to create uniquepackages, so that medical institutions can select and use our
products with confidence.

Kyoso Mirai
Under the corporate slogan, “Total Commitment to good health, The
Kyoso Mirai Group, with TOHO HOLDINGS as its core company, as acorporate group engaged in the medical, health and nursing care sector,
conducts businesses such as pharmaceutical wholesaling, management ofdispensing pharmacies, manufacture and sale of pharmaceuticals andothers, development and provision of customer support systems, etc., andat the same time, actively promotes community healthcare collaborationand makes positive commitments to the home medical and nursing caresector. As our businesses are developed, our wish gets deeper and greater on the basis of our philosophy,“Kyoso Mirai” that each of us are gathered with the same will and make the future full of hope.

*Including affiliated companies

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TOHO HOLDINGS CO., LTD. / Company profile

TOHO HOLDINGS CO., LTD. / Company Profile4

Phrmaceuticalwholesaling

SDGs MarksBusiness infrastructures

The strong business infrastructure ensures
a stable supply of pharmaceuticals andthe provision of our services.
The Group’s business infrastructure is constantly linking missioncritical systems managing sales, inventory, etc. with information
systems managing sales operation, customers, etc. for automateddata processing. In inventory management, in particular, the systemprocesses incoming and outgoing shipments in real time to ensurethat the inventory data always matches the actual inventory on the
shelves. This enables sales offices, distribution centers, and callcenters to be linked with each other and to provide customers withreal-time information on inventory status and delivery dates. We
have also focused on traceability (tracking records) of
pharmaceutical products for many years. With the development ofa system that manages each product by expiration date and lot
number, we have built a thorough mechanism that enables us tocentrally manage all necessary information, whether delivery
orders are issued by a sales office or distribution center anywherein Japan from Hokkaido to Okinawa. This robust business
infrastructure has enabled us to develop pharmaceutical ordering
information terminal ENIF, which checks the inventory status when
receiving orders and immediately returns scheduled delivery data
to the customer concerned, and subsequent customer support
systems. In terms of logistics, the core system and those of all
distribution centers are linked to help facilitate inter-center transfer
of products. This means we are now equipped with a complete
mechanism that allows distribution centers to complement eachother in the event of an emergency.

Sales support terminal

MeissaCustomer support system

ENIF

Mizar

Core system

ClientAutomatic order receiving

Call center

Inbound
OutboundAccurate operations thatmatch physical inventory withtheoretical inventory in realtime

Installaction ofprivate electoric
generators

Order receiving from
customers

Sales office

Trace movement of carriers and checkthe delivery status at the call center

Achieving integration of order
receiving and desk work as wellas labor saving at sales offices by
expanding call centers

Disaster control
network

Shipment from sales offices
No inspection atsome clients at thetime of delivery

Distribution center
Patented

Labor saving by robotic
picking

Direct delivery from distribution centers
Shipping accuracy of distribution centers is 99.99999％,
achieving efficient and ccurate distribution.

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TOHO HOLDINGS CO., LTD. / Company profile

TOHO HOLDINGS CO., LTD. / Company Profile6

Phrmaceuticalwholesaling

SDGs Marks

Distribution center

Achieve the highest level of quality and safety in the industry as well as
efficient logistics

We are striving to evolve our logistics system, thoroughly promoting efficiency andtraceability.
Prescription pharmaceuticals are directly linked to lives and health of patients.
For fulfilling our mission to distribute secure and safe pharmaceuticals, we achieve the highest level ofquality (thorough quality control), safety (traceability) and efficiency (establishment of the efficient logistics
environment) by introducing cutting-edge technologies.
TBC Sapporo
Since 2013

Distribution
centers
covering theentire country（TBC）

Since 2022

TBC Sano（OTC）
Since 1998

Since 2018

"TBC DynaBASE" is a logistics center with cutting-edge technologies for prescription pharmaceuticals built
in the "Keihin Truck Terminal," an area designated by the Tokyo Metropolitan Government as a wide-areatransportation base in the event of a disaster.

Disaster response in the Tokyo metropolitan area
Being located inside the Loop Road No. 7 and near "Ariake-no-Oka," themain wide-area disaster management base facility, it's capable of providing
pharmaceuticals promptly and smoothly in the event of a disaster such as
the Tokyo Inland Earthquake. A seismic isolation structure is used not only
for the buildings but also for the adjacent rampway (slope passage). In
addition, equipped with a large private power generator (5,000 kVA), it canrun at full capacity for 72 hours during emergencies.

The world’s highest-level automation technologies

TBC Hokuriku

TBC Hiroshima

Highly functional distribution center "TBC DynaBASE"TBC Saitama

TBC Hanshin

Since 2014

Since 2013

TBC Omiya（OTC）
Since 2015

TBC Kyushu
Since 2011

TBC DynaBASE
Since 2020

With the world's highest-level automation technologies, we aim to achieve a
robot piece-picking rate of 9 5 %. We also aim to attain more than seven-nines(99.99999%) shipping accuracy, which has been achieved by other logistics
centers. Based on this high shipping accuracy, we will establish a delivery
system based on a "No inspection system," which may contribute toimproving the operational efficiency of our customers by omitting
inspections at the time of delivery.

Thorough quality control
We have acquired ISO9001:2015 certification (an international standard for quality management systems for products
and services) and conducts quality control. In addition, TBC Saitama, TBC Hiroshima and TBC DynaBASE haveestablished logistics systems that comply with Good Distribution Practice (GDP) Guidelines for pharmaceuticals, andare working to further strengthen them.

Initiatives for specialty pharmaceuticals
In recent years, the pharmaceutical distribution industry has seen an increase in specialty pharmaceuticals,
including orphan drug and high-cost medicines, many of which require special management methods such astemperature control during the transport process. In specialty pharmaceuticals, we have established a stable
and continuous logistics system backed by high shipping accuracy and an advanced temperature control
system.

TBC WILL Shinagawa（Reagent/Medical equipment）

Since 2021
TBC WILL Shinagawa, a distribution center specializing inreagents and medical materials, handles a wide variety of
products that cover disease prevention, diagnosis, andtreatment. Thanks to its large cold-storage warehouse of1223.14 m2, it is capable of thorough temperature control
of not only room-temperature but also ultra-lowtemperature products, and realizes product traceability,
including lot control.

For more information, please visit the website.

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TOHO HOLDINGS CO., LTD. / Company profile

Aiming to establish an optimal distribution system for specialty pharmaceuticals
We are also taking on the challenge of establishing a one-stop logistics
system for specialty pharmaceuticals. TBC DynaBASE, TBC WILL Shinagawa,
and KYOSOMIRAI PHARMA CO., LTD.’s Shinagawa Plant are conveniently
located near Haneda Airport. By taking this locational advantage and fully
cooperating with bio-ventures and other pharmaceutical manufacturers andventure companies with cutting-edge technologies in their efforts to address
distribution issues, including raw material transportation, clinical trial
logistics, manufacturer logistics, and wholesale logistics, we aim to establish
a distribution platform for specialty pharmaceuticals such as gene therapy
drugs, regenerative medical products, and cellular medical products.
・The SALM device offers thorough control from shipment to use consistently in order to maintain thequality of specialty pharmaceuticals that require a rigorous temperature control and record.

TOHO HOLDINGS CO., LTD. / Company Profile8

Phrmaceuticalwholesaling

SDGs Marks

Customer support system
Our customer support systems are constantly evolving not only in order to deliver products to our customer
medical institutions, but also in order to pursue benefits and convenience for the patients who are the endusers.

LXMATE HeLios

Byouin-Navi

This system enables patients to avoid any waitingtime for an appointment. The patients can personally
get access at any time of the day via telephone, theInternet, or mobile phone
to make a medical careappointment and thenconfirm or change orcancel the appointment
at any time.

It gives information with high accuracy and instant byusing our own detailed data MSes collect. In
combination with initial examination reservation
service, you can completea procedure from searchingfor medical institutions tobooking.

ENIF

Mizar

This system makes pharmaceutical ordering
operations dramatically more efficient. Any user caneasily place an order simply by scanning the relevantbarcode through the terminal, which eliminates theneed for cumbersome ordering
operations via the telephone.

This system realizes the centralized management ofsales, inventories and accounts receivable for all
pharmacy stores at the headquarters. With automaticorder placement based on prescription data, it
contributes to significantly
reduce pharmacists’ timeand efforts needed forordering.

ENIFvoice SP+A

ENI-Pharmacy

This is an all-in-one automatic voice-recognitionand electronic medication history recording system.
Pharmacists can easily record medication history byvoice-recognition and, furthermore, it enables interterminal and inter-store
data sharing of medication
history and voice input via
a cloud server.

This system sends prescription information to a
designated pharmacy in accordance with the simple
touch panel operations performed
by a patient. It reduces the waitingtime for the patient at a pharmacy,
while at the same time enabling
the designated pharmacist to
spend more time in dispensing.

ENIFvoice Core

ENIFwin Nex-Sus

ENIFclub

ENIFmeDokoshiru Dengonban

eKenkoshop

Automated medical care appointment system

・KAITOS・ENIF・FutureENIF-WEB
・ENIFclub・ENIFvoice SP
・ENIFvoice SP+A
・ENIFvoice Core・Core-POS・ENI-Pharmacy

・Mizar・ENIFme・eKenkoshop
・ENIFvision
Pharmacy
・POCT
Temporally
Transferred
Pharmacist
・・Support for opening of new pharmacies
・Nutritionists

・KAITOS・Initial Examination Reservation Service
・LXMATE HeLios
・Byouin-Navi
・The website creation service
・Wholesale in Small Lots
(PFP)
・ENIF
・FutureENIF-WEB
・ENIFme・ENIFvision
Clinic・POCT・Support for opening of new Clinics
・Nutritionists

Pharmaceutical ordering system

Patient

・ENI-Pharmacy
・ENIFwin
・ENIFwin Nex-Sus
・ENIFvision
・ENIFme・Wholesale in Small Lots
(PFP)
・SPD

Hospital

All-in-one automatic voice-recognition and electronic medication
history recording system

Lineup
KAITOS

Initial Examination Reservation Service

In conjunction with “Byouin-Navi”, the online
medical examination/dosing guidance system“KAITOS” enables a series of processes fromsearching clinics thatprovide online medical
examination services,making reservations,
receiving such online
services, to settlement.

This service enables any user patient who isintending to make his/her initial hospital visit toarrange the initial medical care appointment inadvance upon browsing
the website of a given
medical institution or
search sites for medical
institutions via his/hercomputer or smartphone.

Online Medical Examination / Dosing Guidance System

Online appointment service for first patients

All-in-one system for receipt computing and electronic med-ication
history recording with automatic voice-recognition
Members service to visualize and resolve pharmacy management
issuesUnidentified person information sharing service

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TOHO HOLDINGS CO., LTD. / Company profile

Web-portal site for finding hospitals / clinics

Centralized administration system of pharmacy operations

System supporting the separation of dispensing and prescribing
function

An integrated in-hospital distribution and inventory-management
systemWholesale of medical materials in small lots
Service which enables users to order OTC drugs via the Internet andreceive them at a pharmacy

TOHO HOLDINGS CO., LTD. / Company Profile

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Leveraging the collective strength of the Group

Initiatives to Enhance Corporate Value SDGs Marks

SDGs Marks

Contribution to local healthcare

Promotion of sustainable management

While Japan’s population aging is advancing, efforts are underway to realize a “community comprehensive
healthcare system” in which the community as a whole provides services that enable the elderly to continue
to live in their familiar neighborhoods. Through the operation of dispensing pharmacies, we ourselves areactively involved as a member of the inter-professional collaboration project, and provide community
health-care support to medical institutions and patients with whom we do business in various aspects ofmedical care, nursing care, disease prevention, and lifestyle.

We, the TOHO HOLDINGS Group, would like to contribute to people who desire health by fulfilling oursocial mission of a stable supply of pharmaceuticals. In addition, with the aim of achieving stable and longterm corporate growth and a sustainable society, the Group identifies issues in the areas of the environment,
society, governance, and compliance, and promotes initiatives to resolve them.

Visiting nursing
stationIn-home care
support oﬃce

Visiting
nurse

Care
managerpatient nursing care

●Establishment of the Group Compliance and Risk Management Committee

We hold meetings of the Group Compliance Risk Management Committee regularly based on the Risk
Management Basic Rules. In addition, we have established the Code of Ethics, and training is provided to all
employees to make them fully aware of it.

●Conducting compliance training

creation of care plan

ClinicStaﬀ

Home-carepatients andtheir families

To ensure safe and secure delivery of pharmaceuticals at any time, we have established distribution centersthroughout Japan. Distribution centers have many air conditioners and a lot of lighting equipment and use largematerial handling equipment and robots. This results in higher electricity consumption than other business offices.
For this reason, we have introduced BEMS at our distribution centers to manage the consumption.

cooperation

ConsumerNursing homeresidents
Community
cooperative hospitals

Health promotion support andconsultation functions for local residents

medical examination

DoctorDrug management・Dosing guidance
Pharmacist

drug management・
dosing guidance

Our group dispensing pharmacies（health-supporting local pharmacies）
Pharmacist

Registeredsellers

Maximize the value of human capital

The Group has improved the program to develop human resources who are capable of creating customer value.
With broad utilization of human resources regardless of gender, nationality, age, etc. and respecting individualities,
capabilities and teamwork of employees, we nurture a free-spirited corporate culture and work on human resources
development, aiming at mid- and long-term enhancement of corporate value through continuing sustainable growthand establishment of our corporate brand.

Self-health checks, support for andresponse to health checks

PharmacyWork-Life Balance
As a part of our work-life balance initiatives, we opened the Mirai Nursery at the
TBC Sapporo Distribution Center. We participate in the Support for Balancing Workand Childcare promoted by the national government, and will continue working tocreate an environment where employees can work flexibly and actively.

Nutritionist

Main Supports of TOHO HOLDINGS
Multiprofessional collaboration

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Pharmaceuticals/
OTC drugs/Nursing food/
Health foods and others

Sphygmomanometer/
Blood glucose meter/
Health appliance andothersExercise therapy proposals/
Health seminar/Education
and Training/Dietary
guidance/Nutritionalcounseling and others

Finding hospitals/
Automated medical careappointment system/
Online medical
examination and others

TOHO HOLDINGS CO., LTD. / Company profile

Compliance training

Promote environmental load reduction

Community

watching forwandering andother activities ofthe elderly in thecommunity

We implement monthly compliance training for all employees of ourGroup. All employees involved in sales are required to take an“Antimonopoly Law training ” and acquire legal knowledge ofantimonopoly law and related regulations.

Doctorhome visitation

Local
governments

Full Enforcement of Legal Compliance

Mirai Nursery
Hygiene materials/
Dispensing equipment
and others

Unidentiﬁed person
information sharing service/Observation agreements
and others

Toward Further Enhancement of Corporate Governance
The Company and the Group are committed to enhancing the corporate governance as one of the most importantmanagerial tasks, because we recognize that it is important to enhance the auditing and supervisory functions
concerning corporate management, achieve full compliance, and improve the transparency of management so that
we can sincerely fulfill our responsibilities towards various stakeholders, including customers, business partners,
shareholders, employees, and government entities, and enhance our corporate value as sustainable companies.

TOHO HOLDINGS CO., LTD. / Company Profile

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