高齢者ブレインバンク http://www2.tmig.or.jp/brainbk/
リソース研究_研究成果_2013 年
1.

Funabe S, Takao M, Saito Y, Hatsuta H, Sugiyama M, Ito S, Kanemaru K, Sawabe M, Arai T,
Mochizuki H, Hattori N, Murayama S: Neuropathologic analysis of Lewy- related alphasynucleinopathy in olfactory mucosa. Neuropathology 2013, 33, 47-58
2014年神経病理学会最優秀論文賞受賞

2.

Kakuda N, Akazawa K, Hatsuta H, Murayama S, Ihara Y; Japanese Alzheimer's Disease
Neuroimaging Initiative. Suspected limited efficacy of γ-secretase modulators. Neurobiol ofAging 2013, 34: 1101-1104

3.

Miyakawa S, Ogino M, Funabe S, Uchino A, Shimo Y, Hattori N, Ichinoe M, Mikami T, Saegusa M,Mizuno Y, Murayama S, Mochizuki H: Lewy bodies and parkinsonism in a patient with a parkin
mutation. Movement disorder, 2013, 28(3): 388-391

4.

Wen Y, Miyashita A, Kitamura N, Tsukie T, Saito Y, Hatsuta H, Murayama S, Kakita A, Takahashi H, Akatsu
H, Yamamoto T, Kosaka K, Yamaguchi H, Akazawa K, Ihara, Y and Kuwano R. SORL1 is geneticallyassociated with neuropathologically characterized late-onset Alzheimer's disease. J Alzheimers Dis
2013, 35 (2): 387-394
5.

Kakuda N, Akazawa K, Hatsuta H, Murayama S, Ihara Y and Japanese Alzheimer's Disease Neuroimaging,

Initiative: Suspected limited efficacy of gamma-secretase modulators. Neurobiol Aging 2013, 34 (4):1101-1104
6.

Nonaka T, Masuda-Suzukake M, Arai T, Hasegawa Y, Akatsu H, Obi T, Yoshida M, Murayama S, Mann D.
M, Akiyama H and Hasegawa M. Prion-like Properties of Pathological TDP-43 Aggregates from

Diseased Brains. Cell Rep 2013, 4 (1): 124-134
7.

Sakurai Y, Ishii K, Sonoo M, Saito Y, Murayama S, Iwata A, Hamada K, Sugimoto I, Tsuji S and Mannen T.
Progressive apraxic agraphia with micrographia presenting as corticobasal syndrome showing extensive
Pittsburgh compound B uptake. J Neurol 2013, 260 (8): 1982-1991

8.

Tsuiji H, Iguchi, Y, Furuya A, Kataoka A, Hatsuta H, Atsuta N, Tanaka F, Hashizume Y, Akatsu H,
Murayama S, Sobue G and Yamanaka K. Spliceosome integrity is defective in the motor neuron diseases

ALS and SMA. EMBO Mol Med 2013, 5 (2): 221-234
9.

The Multiple-System Atrophy Research Collaboration. Mutations in COQ2 in familial and sporadic
multiple-system atrophy. N Engl J Med. 2013, 369:233-244

10. Higuma M, Sanjo N, Satoh K, Shiga Y, Sakai K, Nozaki I, Hamaguchi T, Nakamura Y, Kitamoto T, ShirabeS, Murayama S, Yamada M, Tateishi J and Mizusawa H: Relationships between clinicopathologicalfeatures and cerebrospinal fluid biomarkers in Japanese patients with genetic prion diseases. PLoS One
2013, 8(3): e60003.doi:10.1371/journal.pone.0060003
11. Yamamoto T, Oishi T, Higo N, Murayama S, Sato A, Takashima I, Sugiyama Y, Nishimura Y, Murata Y,Yoshino-Saito K, Isa T and Kojima T. Differential expression of secreted phosphoprotein 1 in the motor
cortex among primate species and during postnatal development and functional recovery. PLoS One 8
2013, 8(5): e65701. doi:10.1371/journal.pone.0065701
12. Dan A, Takahashi M, Masuda-Suzukake M, Kametani F, Nonaka T, Kondo H, Akiyama H, Arai T,Mann DMA, Saito Y, Hatsuta H, Murayama S, Hasegawa M: Extensive deamidation at asparagine
residue 279 accounts for weak immunoreactivity of tau with RD4 antibody in Alzheimer’s disease brain.
Acta Neuropathologica Communications 2013, 1:54 doi:10.1186/2051-5960-1-54

1

13. Kobayashi Z, Kawakami I, Arai T, Yokota O, Tsuchiya K, Kondo H, Shimomura Y, Haga C, Aoki N,Hasegawa M, Oshima K, Niizato K, Ishizu H, Terada S, Onaya M, Ikeda M, Oyanagi K, Nakao I,Murayama S, Akiyama H, Muzusawa H: Pathological features of FTLD-FUS in a Japanese popuration:Analyses of nine cases. Jaunal of the Neurological Scienses. 2013, 335: 89-95
14. Mizuta I, Takafuji K, Ando Y, Satake W, Kanagawa M, Kobayashi K, Nagamori S, Shinohara T, Ito M,Yamamoto M, Hattori N, Murata M, Kanai Y, Murayama S, Nakagawa M, Toda T: YY1 binds toα-synuclein 3´-flanking region SNP and stimulartes antisense noncoding RNA expression. Journal of
Human Genetics 2013, 58: 711-719
15. Wen Y, Miyashita A, Kitamura N, Tsukie T, Saito Y, Hatsuta H, Murayama S, Kakita, A, Takahashi H,Akatsu H, Yamamoto T, Kosaka K, Yamaguchi H, Akazawa K, Ihara Y: SORL1 is Genetically
Associated with Neuropathologically Characterized Late-Onset Alzheimer’s Disease. Journal ofAlzheimer's Disease 2013, 35: 387-394
16. Nishimoto Y, Nakagawa S, Hirose T, Okano HJ, Takao M, Shibata S, Suyama S, Kuwako
K, Imai T, Murayama S, Suzuki N, Okano H. The long non-coding RNA nuclear-enrichedabundant transcript 1_2 induces paraspeckle formation in the motor neuron during theearly phase of amyotrophic lateral sclerosis. Molecul Brain 2013, 6(4): 31.
17. Uchida Y, Gomi F, Murayama S, Takahashi H: Calsyntenin-3 C-terminal fragment
accumulates in dystrophic neurites surrounding Aß plaques in Tg2576 mouse andAlzheimer’s disease brains: its neurotoxic role in mediating dystrophic neurite formation.
Am J Patho 2013, 182(5) 1718-1726

18. Sugiyama M, Takao M, Hatsuta H, Funabe S, Ito S, Obi T, Tanaka F, Kuroiwa Y,Murayama S. Increased number of astrocytes and macrophages/microglial cellsin the corpus callosum in amyotrophic lateral sclerosis. Neuropathology 2013,33(6):591-599
19. Suzuki K, Takao M, Katayama Y, Mihara B. Acute myelitis associated with HCVinfection. BMJ case reports 2013, doi:10.1136/bcr-2013-008934.
20. Takeda A, Shimada H, Tamura A, Yasui M, Yamamot K, Itoh K, Ataka S, Tanaka S,Ohsawa M, Hatsuta H, Hirano M, Sakamot H, Ueno S, Nakamura Y, Tsutada T, Miki T. A
case of anti-N-methyl-D-asparatate receptor encephalitis with multiple sclerosis-likedemyelinated lesions. Multiple Sclerosis and Related Disorders. 2013, 3(3):391-397

2