原著論文リスト

Yukio Yoneda, Ph.D.
May 10, 2016

1.

Onishi Y., Fukasawa K., Ozaki K., Iezaki T., Yoneda Y. and Hinoi E. (2016) GDF1 is a novel
mediator of macrophage infiltration in brown adipose tissue of obese mice. Biochem. Biophys.
Reports, in press.

2.

Takarada T., Kou M., Hida M., Fukumori R., Nakamura S., Kutsukake T., Kuramoto N., Hinoi
E. and Yoneda Y. (2016) Protective upregulation of activating transcription factor-3 against
glutamate neurotoxicity in neuronal cells under ischemia. J. Neurosci. Res. 94, 378-388. doi:
10.1002/jnr.23723.

3.

Takarada T., Nakamichi N., Nakazato R., Kakuda T., Kokubo H., Ikeno S., Nakamura S.,
Kuramoto N., Hinoi E. and Yoneda Y. (2016) Possible activation by the green tea amino acidtheanine of mammalian target of rapamycin signaling in undifferentiated neural progenitor cells
in vitro. Biochem. Biophys. Reports 5, 89-95.

4.

Takarada T., Nakazato R., Tsuchikane A., Fujikawa K., Iezaki T., Yoneda Y. and Hinoi E. (2016)
Genetic analysis of Runx2 function during intramembranous ossification. Development 143,
211-218. doi: 10.1242/dev.128793.

5.

Iezaki T., Onishi Y., Ozaki K., Fukasawa K., Takahata, Y., Nakamura Y., Fujikawa K., TakaradaT., Yoneda Y., Yamashita Y., Shioi G. and Hinoi E. (2016) The transcriptional modulator
interferon-related developmental regulator 1 in osteoblasts suppresses bone formation andpromotes bone resorption. J. Bone Miner. Res. 31, 573-584. doi: 10.1002/jbmr.2720.

6.

Takarada T., Ogura M., Nakamichi N., Kakuda T., Nakazato R., Kokubo H., Ikeno S., Nakamura
S., Kutsukake T., Hinoi E. and Yoneda Y. (2016) Upregulation of Slc38a1 gene along withpromotion of neurosphere growth and subsequent neuronal specification in undifferentiatedneural progenitor cells exposed to theanine. Neurochem. Res. 41, 5-15. doi: 10.1007/s11064015-1591-4.

7.

Ozaki K., Okamoto M., Fukasawa K., Iezaki T., Onishi Y., Yoneda Y., Sugiura M. and Hinoi E.
(2015) Daily intake of -cryptoxanthin prevents bone loss by preferential disturbance ofosteoclastic activation in ovariectomized mice. J. Pharmacol. Sci. 129, 72-77. doi:
10.1016/j.jphs.2015.08.003.

8.

Fujikawa K., Fukumori R., Nakamura S., Kutsukake T., Takarada T. and Yoneda Y. (2015)
Potential interactions of calcium-sensitive reagents with zinc ion in different cultured cells. PLoS
ONE 10, e0127421.

9.

Nakazato R.*, Takarada T.*, Ikeno S., Nakamura S., Kutsukake T., Hinoi E. and Yoneda Y.
(2015) Upregulation of runt-related transcription factor-2 through CCAAT enhancer binding
protein-beta signaling pathway in microglial BV-2 cells exposed to ATP. J. Cell. Physiol. 230,
2510-2521. *Equally contributed. doi: 10.1002/jcp.24988

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10. Takarada T., Nakamichi N., Kakuda T., Nakazato R., Kokubo H., Ikeno S., Nakamura S., Hinoi
E. and Yoneda Y. (2015) Daily oral intake of theanine prevents the decline of 5-bromo-2'deoxyuridine incorporation in hippocampal dentate gyrus with concomitant alleviation of
behavioral abnormalities in adult mice with severe traumatic stress. J. Pharmacol. Sci. 127, 292297.
11. Hinoi E., Iezaki T., Ozaki K. and Yoneda Y. (2014) Nuclear factor-B is a common upstream
signal for growth differentiation factor-5 expression in brown adipocytes exposed to proinflammatory cytokines and palmitate. Biochem. Biophys. Res. Commun. 452, 974-979.
12. Hinoi E., Iezaki T., Fujita H., Watanabe T., Odaka Y., Ozaki K. and Yoneda Y. (2014) PI3K/Akt
is involved in brown adipogenesis mediated by growth differentiation factor-5 in association
with activation of the Smad pathway. Biochem. Biophys. Res. Commun. 450, 255-260.
13. Nakazato R.*, Takarada T.*, Watanabe T., Nguyen B.T., Ikeno S., Hinoi E. and Yoneda Y.
(2014) Constitutive and functional expression of runt-related transcription factor-2 by microglial
cells. Neurochem. Int. 74, 24-35. *Equally contributed.
14. Kubo M., Fukui M., Ito Y., Kitao T., Shirahase H., Hinoi E. and Yoneda Y. (2014) Insulin
sensitization by a novel partial peroxisome proliferator-activated receptor  agonist with protein
tyrosine phosphatase 1D inhibitory activity in experimental osteoporotic rats. J. Pharmacol. Sci.
124, 276-285.
15. Hinoi E., Nakamura Y., Takada S., Fujita H., Iezaki T., Hashizume S., Takahashi S., Odaka Y.,
Watanabe T. and Yoneda Y. (2014) Growth differentiation factor-5 promotes brown
adipogenesis in systemic energy expenditure. Diabetes 63, 162-175. doi: 10.2337/db13-0808.
16. Takarada T., Hinoi E., Nakazato R., Ochi H., Xu C., Tsuchikane A., Takeda S., Karsenty G.,
Abe T., Kiyonari H. and Yoneda Y. (2013) An analysis of skeletal development in osteoblastand chondrocyte-specific Runx2 knockout mice. J. Bone Miner. Res. 28, 2064-2069. doi:
10.1002/jbmr.1945.
17. Nguyen Q.L.,*, Nguyen T.B.*, Takarada T., Takarada-Iemata M., Hinoi E. and Yoneda Y.
(2013) A negative correlation between Per1 and Sox6 expression during chondrogenic
differentiation in pre-chondrocytic ATDC5 cells. J. Pharmacol. Sci. 122, 318-325. *Equallycontributed.
18. Fukumori R.*, Takarada T.*, Nakazato R., Fujikawa K., Kou M., Hinoi E. and Yoneda Y. (2013)
Selective inhibition by ethanol of mitochondrial calcium influx mediated by uncoupling protein2 in relation to N-methyl-D-aspartate cytotoxicity in cultured neurons. PLoS ONE 8, e69718.
*Equally contributed.
19. Takarada T.*, Kou M.*, Nakamichi N., Ogura M., Ito Y., Fukumori R., Kokubo H., Acosta G.B.,
Hinoi E. and Yoneda Y. (2013) Myosin VI reduces proliferation, but not differentiation, in
pluripotent P19 cells. PLoS ONE 8, e63947. *Equally contributed.
20. Nakamura Y.*, Hinoi E.*, Iezaki T., Takada S., Hashizume S., Takahata Y., Tsuruta E.,
Takahashi S. and Yoneda Y. (2013) Repression of adipogenesis through promotion of Wnt/ßcatenin signaling by TIS7 up-regulated in adipocytes under hypoxia. BBA Mol. Basis Dis. 1832,1117-1128. *Equally contributed.
21. Fujita H.*, Hinoi E.*, Watanabe T., Iezaki T., Takamori M., Ogawa S. and Yoneda Y. (2013)
Prevention of bone loss after ovariectomy in mice with preferential overexpression of thetranscription factor Paired box-5 in osteoblasts. Biol. Pharm. Bull. 36, 481-484. *Equallycontributed.
22. Kikuta M., Shiba T., Yoneyama M., Kawada K., Yamaguchi T., Hinoi E., Yoneda Y. and Ogita
K. (2013) In vivo and in vitro treatment with edaravone promotes proliferation of neural2

progenitor cells generated following neuronal loss in the mouse dentate gyrus. J. Pharmacol.
Sci. 121, 74-83.
23. Iitsuka I., Motoyoshi-Yamashiro A., Moriyama M., Kannan-Hayashi Y., Fujimoto Y., Takano K.,
Murakami K., Yoneda Y. and Nakamura Y. (2012) Extracellular superoxide dismutase in cultured
astrocytes: decrease in cell-surface activity and increase in medium activity bylipopolysaccharide-stimulation. Neurochem. Res. 37, 2108-2116.
24. Hinoi E., Nakatani E., Yamamoto T., Iezaki T., Takahata Y., Fujita H., Ishiura R., Takamori M.
and Yoneda Y. (2012) The transcription factor paired box-5 promotes osteoblastogenesis throughdirect induction of Osterix and Osteocalcin. J. Bone Miner. Res. 27, 2526-2534.
25. Ogura M.*, Kakuda T.*, Takarada T.*, Nakamichi N., Fukumori R., Kim Y.H., Hinoi E. and
Yoneda Y. (2012) Promotion of both proliferation and differentiation in pluripotent P19 cellswith stable overexpression of the glutamine transporter Slc38a1. PLoS ONE 7, e48270. *Equallycontributed.
26. Takarada T., Kodama A., Hotta S., Mieda M., Shimba S., Hinoi E. and Yoneda Y. (2012) Clockgenes influence gene expression in growth plate and endochondral ossification in mice. J. Biol.
Chem. 287, 36081-36095.
27. Takarada T.*, Nakamichi N.*, Kitajima S., Fukumori R., Nakazato R., Nguyen Q.L., Kim Y.H.,
Fujikawa K., Kou M. and Yoneda Y. (2012) Promoted neuronal differentiation after activationof alpha4/beta2 nicotinic acetylcholine receptors in undifferentiated neural progenitors. PLoS
ONE 7, e46177. *Equally contributed.
28. Takahata Y.*, Hinoi E.*, Takarada T., Nakamura Y., Ogawa S. and Yoneda Y. (2012) Positive
regulation by GABAB receptor subunit-1 of chondrogenesis through acceleration of nuclear
translocation of activating transcription factor-4. J. Biol. Chem. 287, 33293-33303. *Equallycontributed.
29. Takarada T.*, Nakamichi N.*, Kawagoe H., Ogura M., Fukumori R., Nakazato R., Fujikawa K.,
Kou M. and Yoneda Y. (2012) Possible neuroprotective property of nicotinic acetylcholine
receptors in association with predominant upregulation of glial cell line-derived neurotrophic
factor in astrocytes. J. Neurosci. Res. 90, 2074-2085. *Equally contributed.
30. Ogawa K., Takasu K., Shinohara S., Yoneda Y. and Kato A. (2012) Pharmacologicalcharacterization of lysophosphatidic acid-induced pain with clinically relevant neuropathic pain
drugs. Eur. J. Pain 16, 994-1004.
31. Fukumori R.*, Takarada T.*, Kambe Y., Nakazato R., Fujikawa K. and Yoneda Y. (2012)
Possible involvement of mitochondrial uncoupling protein-2 in cytotoxicity mediated byacquired N-methyl-D-aspartate receptor channels. Neurochem. Int. 61, 498-505. *Equallycontributed.
32. Fujita H.*, Hinoi E.*, Nakatani E., Yamamoto T., Takarada T. and Yoneda Y. (2012) Possible
modulation of process extension by N-methyl-D-aspartate receptor expressed in osteocytic
MLO-Y4 cells. J. Pharmacol. Sci. 119, 112-116. *Equally contributed.
33. Iezaki T.*, Hinoi E.*, Yamamoto T., Ishiura R., Ogawa S. and Yoneda Y. (2012) Ameliorationby the natural polyamine, spermine, of cartilage and bone destruction in rats with collageninduced arthritis. J. Pharmacol. Sci. 119, 107-111. *Equally contributed.
34. Fujikawa K.*, Nakamichi N.*, Kato S., Fukumori R., Hida M., Takarada T. and Yoneda Y.
(2012) Delayed mitochondrial membrane potential disruption by ATP in cultured rat
hippocampal neurons exposed to N-methyl-D-aspartate. J. Pharmacol. Sci. 119, 20-29.
*Equally contributed.

335. Takarada T., Takarada-Iemata M., Takahata Y., Yamada D., Yamamoto T., Nakamura Y., Hinoi
E. and Yoneda Y. (2012) Osteoclastogenesis is negatively regulated by D-serine produced byosteoblasts. J. Cell. Physiol. 227, 3477-3487.
36. Yamamoto T.*, Hinoi E.*, Fujita H., Iezaki T., Takahata Y., Takamori M. and Yoneda Y. (2012)
Natural polyamines spermidine and spermine prevent bone loss through preferential disturbanceof osteoclastic activation in ovariectomized mice. Br. J. Pharmacol. 166, 1084-1094. *Equallycontributed.
37. Hinoi E., Ochi H., Takarada T., Nakatani E., Iezaki T., Nakajima H., Fujita H., Takahata Y.,
Hidano S., Kobayashi T., Takeda S. and Yoneda Y. (2012) Positive regulation of osteoclastic
differentiation by growth differentiation factor-15 up-regulated in osteocytic cells under hypoxia.
J. Bone Miner. Res. 27, 938-949.
38. Tran H.-Y.P., Shin E.-J., Saito K., Nguyen X.-K.T., Chung Y.H., Jeong J.H., Bach J.-H., Park
D.H., Yamada K., Nabeshima T., Yoneda Y. and Kim H.-C. (2012) Protective potential of IL-6
against trimethyltin-induced neurotoxicity in vivo. Free Radic. Biol. Med. 52, 1159-1174.
39. Nakamura Y., Nakamichi N., Takarada T., Ogita K. and Yoneda Y. (2012) Transferrin receptor-1
suppresses neurite outgrowth in neuroblastoma Neuro2A cells. Neurochem. Int. 60, 448-457.
40. Gono T.*, Takarada T.*, Fukumori R., Kawaguchi Y., Kaneko H., Hanaoka M., Katsumata Y.,
Yoneda Y. and Yamanaka H. (2011) NR2-reactive antibody decreases cell viability throughaugmentation of Ca2+ influx in systemic lupus erythematosus. Arthritis Rheum. 63, 3952-3959.
*Equally contributed.
41. Shin E.-J., Jeong J.-H., Chung Y.H., Kim W.-K., Ko K.-H., Bach J.-H., Hong J.-S., Yoneda Y.
and Kim H.C. (2011) Role of oxidative stress in epileptic seizures. Neurochem. Int. 59, 122137.
42. Uno K., Takarada T., Takarada-Iemata M., Nakamura Y., Fujita H., Hinoi E. and Yoneda Y.
(2011) Negative regulation of osteoblastogenesis through downregulation of runt-relatedtranscription factor-2 in osteoblastic MC3T3-E1 cells with stable overexpression of thecystine/glutamate antiporter xCT subunit. J. Cell. Physiol. 226, 2953-2964.
43. Takahata Y.*, Takarada T.*, Hinoi E., Nakamura Y., Fujita H. and Yoneda Y. (2011) Osteoblastic
GABAB receptors negatively regulate osteoblastogenesis toward disturbance ofosteoclastogenesis mediated by receptor activator of nuclear factor-B ligand in mouse bone. J.
Biol. Chem. 286, 32906-32917. *Equally contributed.
44. Nakazato R.*, Takarada T.*, Yamamoto T., Hotta S., Hinoi E. and Yoneda Y. (2011) Selective
upregulation of Per1 mRNA expression by ATP through activation of P2X7 purinergic receptors
expressed in microglial cells. J. Pharmacol. Sci. 116, 350-361. *Equally contributed.
45. Hinoi E. and Yoneda Y. (2011) Possible involvement of glutamatergic signaling machineries inpathophysiology of rheumatoid arthritis. J. Pharmacol. Sci. 116, 248-256.
46. Nakamura Y.*, Hinoi E.*, Takarada T., Takahata Y., Yamamoto T., Fujita H., Takada S.,
Hashizume S. and Yoneda Y. (2011) Positive regulation by GABABR1 subunit of leptin
expression through gene transactivation in adipocytes. PLoS ONE 6, e20167. *Equallycontributed.
47. Kambe Y., Nakamichi N., Takarada T., Fukumori R., Nakazato R., Hinoi E. and Yoneda Y.
(2011) A pivotal role of mitochondrial free calcium in neurotoxicity mediated by N-methyl-Daspartate receptors in cultured rat hippocampal neurons. Neurochem. Int. 59, 10-20.
48. Ogura M., Takarada T., Nakamichi N., Kawagoe H., Sako A., Nakazato R. and Yoneda Y. (2011)
Exacerbated vulnerability to oxidative stress in astrocytic C6 glioma cells with stable
overexpression of the glutamine transporter slc38a1. Neurochem. Int. 58, 504-511.
449. Uno K., Takarada T., Nakamura Y., Fujita H., Hinoi E. and Yoneda Y. (2011) A negative
correlation between expression profiles of runt-related transcription factor-2 andcystine/glutamate antiporter xCT subunit in ovariectomized mouse bone. J. Pharmacol. Sci. 115,309-319.
50. Fukui M.*, Ozawa S.*, Nakamichi N., Nakazato R., Takarada T. and Yoneda Y. (2011) Gradual
downregulation of protein expression of the partner GABABR2 subunit during postnatal brain
development in mice defective of GABABR1 subunit. J. Pharmacol. Sci. 115, 45-55. *Equallycontributed.
51. Takarada-Iemata M., Takarada T., Nakamura Y., Nakatani E., Hori O. and Yoneda Y. (2011)
Glutamate preferentially suppresses osteoblastogenesis than adipogenesis through thecystine/glutamate antiporter in mesenchymal stem cells. J. Cell. Physiol. 226, 652-665.
52. Fukumori R., Takarada T., Nakamichi N., Kambe Y., Kawagoe H., Nakazato R. and Yoneda Y.
(2010) Requirement of both NR3A and NR3B subunits for dominant negative properties on Ca 2+
mobilization mediated by acquired N-methyl-D-aspartate receptor channels into mitochondria.
Neurochem. Int. 57, 730-737.
53. Yun J., Koike H., Ibi D., Toth E., Mizoguchi H., Nitta A., Yoneyama M., Ogita K., Yoneda Y.,
Nabeshima T., Nagai T. and Yamada K. (2010) Chronic restraint stress impairs neurogenesis
and hippocampus-dependent fear memory in mice: possible involvement of a brain-specifictranscription factor Npas4. J. Neurochem. 114, 1840-1851.
54. Akazawa K., Cui Y., Tanaka M., Kataoka Y., Yoneda Y. and Watanabe Y. (2010) Mapping ofregional brain activation in response to fatigue-load and recovery in rats with c-Fos
immunohistochemistry. Neurosci. Res. 66, 372-379.
55. Nakamichi N.*, Fukumori R.*, Takarada T., Kambe Y., Yamamoto T., Matsushima N.,
Moriguchi N. and Yoneda Y. (2010) Preferential inhibition by antidiarrheic 2-methoxy-4methylphenol of Ca2+ influx across acquired N-methyl-D-aspartate receptor channels composedof NR1/NR2B subunit assembly. J. Neurosci. Res. 88, 2483-2493. *Equal contribution.
56. Kambe Y., Nakamichi N., Takarada T., Fukumori R. and Yoneda Y. (2010) Induced tolerance
to glutamate neurotoxicity through downregulation of NR2 subunits of N-methyl-D-aspartate
receptors in cultured rat striatal neurons. J. Neurosci. Res. 88, 2177-2187.
57. Fukumori R.*, Nakamichi N.*, Takarada T., Kambe Y., Matsushima N., Moriguchi N. and
Yoneda Y. (2010) Inhibition by 2-methoxy-4-ethylphenol of Ca2+ influx through acquired andnative N-methyl-D-aspartate receptor channels. J. Pharmacol. Sci. 112, 273-281. *Equallycontributed.
58. Kimura H., Yukitake H., Tajima Y., Suzuki H., Chikatsu T., Morimoto S., Funabashi Y., Omae
H., Ito T., Yoneda Y. and Takizawa M. (2010) ITZ-1 a client-selective Hsp90 inhibitor
efficiently induces heat shock factor 1 activation. Chemistry and Biology 17, 18-27.
59. Tsuritani K., Takeda J., Sakagami J., Ishii A., Eiksson T., Hara T., Ishibashi H., Koshihara Y.,
Yamada K. and Yoneda Y. (2010) Cytokine receptor-like factor 1 is highly expressed in damaged
human knee osteoarthritic cartilage and is involved in osteoarthritis downstream of TGF-β.
Calcif. Tissue Int. 86, 47-57.
60. Ibi D., Nagai T., Koike H., Kitahara Y., Mizoguchi H., Niwa M., Jaaro-Peled H., Nitta A.,
Yoneda Y., Nabeshima T., Sawa A. and Yamada K. (2010) Combined effect of neonatal immune
activation and mutant DISC1 on phenotypic changes in adulthood. Behav. Brain Res. 206, 3237.
61. Nakatani-Pawlak A., Yamaguchi K., Tatsumi Y., Mizoguchi H. and Yoneda Y. (2009) Neonatal
phencyclidine treatment in mice induces behavioral, histological and neurochemical
abnormalities in adulthood. Biol. Pharm. Bull. 32, 1576-1583.
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62. Otsuka N., Tsuritani K., Sakurai T., Kato K., Matoba R., Itoh J., Okuyama S., Yamada K. and
Yoneda Y. (2009) Transcriptional induction and translational inhibition of Arc and Cugbp2 inmice hippocampus after transient global ischemia under normothermic condition. Brain Res.
1287, 136-145.
63. Takarada T., Hojo H., Iemata M., Sahara., Kodama A., Nakamura N., Hinoi E. and Yoneda Y.
(2009) Interference by adrenaline with chondrogenic differentiation through suppression of genetransactivation mediated by Sox9 family members. Bone 45, 568-578.
64. Takarada T.*, Tamaki K.*, Takumi T., Ogura M., Ito Y., Nakamichi N. and Yoneda Y. (2009) A
protein-protein interaction of stress-responsive myosin VI endowed to inhibit neural progenitor
self-replication with RNA binding protein, TLS, in murine hippocampus. J. Neurochem. 110,
1457-1468. *Equal contribution.
65. Ibi D., Nagai T., Kitahara Y., Mizoguchi H., Koike H., Shiraki A., Takuma K., Kamei H., Noda
Y., Nitta A., Nabeshima T., Yoneda Y. and Yamada K. (2009) Neonatal polyl:C treatment inmice results in schizophrenia-like behavioral and neurochemical abnormalities in adulthood.
Neurosci. Res. 64, 297-305.
66. Koike H., Ibi D., Mizoguchi H., Nagai T., Nitta A., Takuma K., Nabeshima T., Yoneda Y. and
Yamada K. (2009) Behavioral abnormality and pharmacologic response in social isolation-reared
mice. Behav. Brain Res. 202, 114-121.
67. Nakamichi N., Takarada T. and Yoneda Y. (2009) Neurogenesis mediated by -aminobutyricacid and glutamate signaling. J. Pharmacol. Sci. 110, 133-149.
68. Takarada T., Takahata Y., Iemata M., Hinoi E., Uno K., Hirai T., Yamamoto T. and Yoneda Y.
(2009) Interference with cellular differentiation by D-serine through antagonism at N-methyl-Daspartate receptors composed of NR1 and NR3A subunits in chondrocytes. J. Cell. Physiol. 220,756-764.
69. Nakamichi N., Ishioka Y., Hirai T., Ozawa S., Tachibana M., Nakamura N., Takarada T. and
Yoneda Y. (2009) Possible promotion of neuronal differentiation in fetal rat brain neuralprogenitor cells after sustained exposure to static magnetism. J. Neurosci. Res. 87, 2406-2417.
70. Nakamura Y.*, Takarada T.*, Kodama A., Hinoi E. and Yoneda Y. (2009) Predominant
promotion by tacrolimus of chondrogenic differentiation to proliferating chondrocytes. J.
Pharmacol. Sci. 109, 413-423. *Equally contributed.
71. Nakanishi Y., Kobayashi D., Asano Y., Sakurai T., Kashimura M., Okuyama S., Yoneda Y.,
Shapiro S.D. and Takayama K. (2009) Clarithromycin prevents smoke-induced emphysema inmice. Amer. J. Resp. Crit. Care Med. 179, 271-278.
72. Takarada T. and Yoneda Y. (2009) Transactivation by runt related factor-2 of matrix
metalloproteinase-13 in astrocytes. Neurosci. Lett. 451, 99-104.
73. Gu B.*, Nakamichi N.*, Zhang W.-S., Nakamura Y., Kambe Y., Fukumori R., Takuma K.,
Yamada K., Takarada T., Taniura H. and Yoneda Y. (2009) Possible protection by
notoginsenoside R1 against neurotoxicity of N-methyl-D-aspartate receptor composed of an
NR1/NT2B heteromeric assembly. J. Neurosci. Res. 87, 2145-2156. *Equally contributed.
74. Shin E.-J., Jeong J.H., Kim A.-Y., Koh Y.H., Nah S.-Y., Kim W.-K., Ko K.H., Kim H.J., Wie
M.-B., Kwon Y.S., Yoneda Y. and Kim H.-C. (2009) Protection against kainate neurotoxicity
by ginsenosides: Attenuation of convulsive behavior, mitochondrial dysfunction, and oxidative
stress. J. Neurosci. Res. 87, 710-722.
75. Maeda M., Furuichi Y., Noto T., Matsuoka N., Mutoh S. and Yoneda Y. (2009) Tacrolimus(FK506) suppresses rt-PA-induced hemorrhagic transformation in a rat thrombotic ischemia
stroke model. Brain Res. 1254, 99-108.
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76. Takahata Y.*, Takarada T.*, Iemata M., Yamamoto T., Nakamura Y., Kodama A. and Yoneda Y.
(2009) Functional expression of beta2 adrenergic receptors responsible for protection against
oxidative stress through promotion of glutathione synthesis after Nrf2 upregulation in
undifferentiated mesenchymal C3H10T1/2 stem cells. J. Cell. Physiol. 218, 268-275. *Equallycontributed.
77. Nakamichi N. and Yoneda Y. (2009) Glutamatergic signaling in neurogenesis. Neurovascular
Medicine, (Maiese K., ed.), pp. 269-288, Oxford University Press, New York.
78. Fukui M.*, Nakamichi N.*, Yoneyama M., Yoshida K., Ozawa S., Kitayama T., Nakamura N.,
Taniura H. and Yoneda Y. (2008) Up-regulation of ciliary neurotrophic factor receptor
expression by GABAA receptors in undifferentiated neural progenitors of fetal mouse brain. J.
Neurosci. Res. 86, 2615-2623. *Equally contributed.
79. Georgiev D.D., Taniura H., Kambe Y., Takarada T. and Yoneda Y. (2008) A critical importanceof polyamine site in NMDA receptors for neurite outgrowth and fasciculation at early stages of
P19 neuronal differentiation. Exp. Cell Res. 314, 2603-2617.
80. Takahata Y.*, Takarada T.*, Osawa M., Hinoi E., Nakamura Y. and Yoneda Y. (2008) Differential
regulation by glycine of cellular maturation in chondrocytes and osteoblasts. Cell Tissue Res.
333, 91-103. *Equally contributed.
81. Yoneyama M.*, Nakamichi N.*, Fukui M., Kitayama T., Georgiev D.D., Makanga J.O.,
Nakamura N., Taniura H. and Yoneda Y. (2008) Promotion of neural differentiation throughactivation of NMDA receptors transiently expressed by undifferentiated neural progenitor cells
in fetal rat neocortex. J. Neurosci. Res. 86, 2392-2402. *Equally contributed.
82. Fukui M.*, Nakamichi N.*, Yoneyama M., Ozawa S., Fujimori S., Takahata Y., Nakamura N.,
Taniura H. and Yoneda Y. (2008) Modulation of cellular proliferation and differentiation
through GABAB receptors expressed by undifferentiated neural progenitor cells isolated fromfetal mouse brain. J. Cell. Physiol. 216, 507-519. *Equally contributed.
83. Montano A.M., Oikawa H., Tomatsu S., Nishioka T., Vogler C., Gutierrez M.A., Oguma T., Tan
Y., Grubb J.H., Dung V.C., Ohashi A., Miyamoto K.I., Orii T., Yoneda Y. and Sly W.S. (2008)
Acidic amino acid tag enhances response to enzyme replacement in mucopolysaccharidosis type
VII mice. Mol. Genet. Metab. 94, 178-189.
84. Nakamichi N.*, Yoshida K.*, Ishioka Y., Makanga J.O., Fukui M., Yoneyama M., Kitayama T.,
Nakamura N., Taniura H. and Yoneda Y. (2008) Group III metabotropic glutamate receptor
activation suppresses self-replication of undifferentiated neocortical progenitor cells. J.
Neurochem. 105, 1996-2012. *Equally contributed.
85. Takarada T. and Yoneda Y. (2008) Glutamate as a signal mediator in bone. J. Pharmacol. Sci.
106, 536-541.
86. Kambe Y., Nakamichi N., Georgiev D.D., Nakamura N., Taniura H. and Yoneda Y. (2008)
Insensitivity to glutamate neurotoxicity mediated by N-methyl-D-aspartate receptors inassociation with delayed mitochondrial membrane potential disruption in cultured rat corticalneurons. J. Neurochem. 105, 1886-1900.
87. Tamaki K., Yamada K., Nakamichi N., Taniura H. and Yoneda Y. (2008) Transient suppressionof progenitor cell proliferation through NMDA receptors in hippocampal dentate gyrus of micewith traumatic stress experience. J. Neurochem. 105, 1642-1655.
88. Kakuda T.*, Hinoi E.*, Abe A., Nozawa A., Ogura M. and Yoneda Y. (2008) Theanine, aningredient of green tea, inhibits [3H]glutamine transport in neurons and astroglia in rat brain. J.
Neurosci. Res. 86, 1846-1856. *Equally contributed.

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89. Ibi D., Takuma K., Koike H., Mizoguchi H., Tsuritani K., Kuwahara Y., Kamei H., Nagai T.,
Yoneda Y., Nabeshima T. and Yamada K. (2008) Social isolation rearing-induced impairmentof the hippocampal neurogenesis is associated with deficits in spatial memory and emotionrelated behaviors in juvenile mice. J. Neurochem. 105, 921-932.
90. Tamaki K., Kamakura M., Nakamichi N., Taniura H. and Yoneda Y. (2008) Upregulation of
Myo6 expression after traumatic stress in mouse hippocampus. Neurosci. Lett. 433, 183-187.
91. Takarada T., Hinoi E., Takahata Y. and Yoneda Y. (2008) Serine racemase suppresseschondrogenic differentiation in cartilage in a Sox9-dependent manner. J. Cell. Physiol. 215, 320328.
92. Takarada T., Hinoi E., Kambe Y., Sahara K., Kurokawa S., Takahata Y. and Yoneda Y. (2007)
Osteoblast protects osteoclast devoid of sodium-dependent vitamin C transporters from oxidative
cytotoxicity of ascorbic acid. Eur. J. Pharmacol. 575, 1-11.
93. Taniura H., Iijima S., Kambe Y., Georgiev D. and Yoneda Y. (2007) Tex261 modulates theexcitotoxic cell death induced by N-methyl-D-aspartate (NMDA) receptor activation. Biochem.
Biophys. Res. Commun. 362, 1096-1100.
94. Sugiyama C.*, Nakamichi N.*, Ogura M., Honda E., Maeda S., Taniura H. and Yoneda Y.
(2007) Activator protein-1 responsive to the group II metabotropic glutamate receptor subtype
in association with intracellular calcium in cultured rat cortical neurons. Neurochem. Int. 51,
467-475. *Equally contributed.
95. Iemata M.*, Takarada T.*, Hinoi E., Taniura H. and Yoneda Y. (2007) Suppression by glutamateof proliferative activity through glutathione depletion mediated by the cystine/glutamate
antiporter in mesenchymal C3H10T1/2 stem cells. J. Cell. Physiol. 213, 721-729. *Equallycontributed.
96. Taniura H., Sng J.C. and Yoneda Y. (2007) Histone modifications in the brain. Neurochem. Int.
51, 85-91.
97. Takahashi K., Nagai T., Kamei H., Maeda K., Matsuya T., Arai S., Mizoguchi H., Yoneda Y.,
Nabeshima T., Takuma K. and Yamada K. (2007) Neural circuits containing pallidotegmental
GABAergic neurons are involved in the prepulse inhibition of the startle reflex in mice. Biol.
Psychiatry 62, 148-157.
98. Uno K.*, Takarada T.*, Hinoi E. and Yoneda Y. (2007) Glutamate is a determinant of cellular
proliferation through modulation of nuclear factor E2 p45-related factor-2 expression in
osteoblastic MC3T3-E1 cells. J. Cell. Physiol. 213, 105-114. *Equally contributed.
99. Matsushima N.*, Nakamichi N.*, Kambe Y., Takano K., Moriguchi N. and Yoneda Y. (2007)
Cytoprotective properties of phenolic antidiarrheic ingredients in cultured astrocytes and neuronsof rat brains. Eur. J. Pharmacol. 567, 59-66. *Equally contributed.
100. Ogura M.*, Taniura H.*, Nakamichi N. and Yoneda Y. (2007) Upregulation of the glutaminetransporter through transactivation mediated by cAMP/protein kinase A signals toward
exacerbation of vulnerability to oxidative stress in rat neocortical astrocytes. J. Cell. Physiol.
212, 375-385. *Equally contributed.
101. Sugiyama C., Kuramoto N., Seko K., Yoneda Y. and Ogita K. (2007) Decreased level ofmitochondrial RNA by glutamate in cultured cortical neurons. Neuroreport 18, 827-830.
102. Hinoi E.*, Takarada T.*, Uno K., Inoue M., Murafuji Y. and Yoneda Y. (2007) Glutamate
suppresses osteoclastogenesis through the cystine/glutamate antiporter. Am. J. Pathol. 170,
1277-1290. *Equally contributed.
103. Yoneyama M.*, Fukui M.*, Nakamichi N., Kitayama T., Taniura H. and Yoneda Y. (2007)
Activation of GABAA receptors facilitates astroglial differentiation induced by ciliary8neurotrophic factor in neural progenitors isolated from fetal rat brain. J. Neurochem. 100, 16671679. *Equally contributed.
104. Takano K., Tabata Y., Kitao Y., Murakami R., Suzuki H., Yamada M., Iinuma M., Yoneda Y.,
Ogawa S. and Hori O. (2007) Methoxyflavones protect cells against endoplasmic reticulum (ER)stress and neurotoxin. Am. J. Physiol. Cell Physiol. 292, C353-361.
105. Moriguchi N.*, Hinoi E.*, Takarada T., Matsushima N., Uno K. and Yoneda Y. (2007) Oraladministration of phenolic antidiarrheic ingredients prevents ovariectomy-induced bone loss.
Biochem. Pharmacol. 73, 385-393. *Equally contributed.
106. Hinoi E., Takarada T., Fujimori S., Wang L., Iemata M., Uno K. and Yoneda Y. (2007) Nuclear
factor E2 p45-related factor 2 negatively regulates chondrogenesis. Bone 40, 337-344.
107. Fujimori S., Hinoi E., Takarada T., Iemata M., Takahata Y. and Yoneda Y. (2006) Possible
expression of a particular gamma-aminobutyric acid transporter isoform responsive to
upregulation by hyperosmolarity in rat calvarial osteoblasts. Eur. J. Pharmacol. 550, 24-32.
108. Wang L.*, Hinoi E.*, Takemori A., Nakamichi N. and Yoneda Y. (2006) Glutamate inhibits
chondral mineralization through apoptotic cell death mediated by retrograde operation of thecystine/glutamate antiporter. J. Biol. Chem. 281, 24553-24565. *Equally contributed.
109. Hinoi E., Ueshima T., Hojo H., Iemata M., Takarada T. and Yoneda Y. (2006) Upregulation of
per mRNA expression by parathyroid hormone through a PKA-CREB-dependent mechanism inchondrocytes. J. Biol. Chem. 281, 23632-23642.
110. Hinoi E., Takarada T., Tsuchihashi Y., Fujimori S., Moriguchi N., Wang L., Uno K. and Yoneda
Y. (2006) A molecular mechanism of pyruvate protection against cytotoxicity of reactive oxygen
species in osteoblasts. Mol. Pharmacol. 70, 925-935.
111. Hinoi E., Fujimori S., Wang L., Hojo H. Uno K. and Yoneda Y. (2006) Nrf2 negatively regulates
osteoblast differentiation via interfering with Runx2 dependent transcriptional activation. J. Biol.
Chem. 281, 18015-18024.
112. Goto Y., Taniura H., Yamada K., Hirai T., Sanada N., Nakamichi N. and Yoneda Y. (2006) The
magnetism responsive gene Ntan1 in mouse brain. Neurochem. Int. 49, 334-341.
113. Takano K., Kitao Y., Inagi R., Momoi T., Matsuyama T., Miyata T., Yoneda Y., Iso H., Stern
D.M., Hori O. and Ogawa S. (2006) A rat model of human FENIB (familial encephalopathy withneuroserpin inclusion bodies). Biochem. Biophys. Res. Commun. 346, 1040-1047.
114. Nakamichi N. and Yoneda Y. (2006) Maturation-dependent reduced responsiveness of
intracellular free Ca2+ ions to repeated stimulation by N-methyl-D-aspartate in cultured rat
cortical neurons. Neurochem. Int. 49, 230-237.
115. Taniura H., Sanada N., Kuramoto N. and Yoneda Y. (2006) A metabotropic glutamate receptor
family gene in Dictyostelium discoideum. J. Biol. Chem. 281, 12336-12343.
116. Ogura M., Nakamichi N., Takano K., Oikawa H., Kambe Y., Ohno Y., Taniura H. and Yoneda
Y. (2006) Functional expression of a glutamine transporter responsive to downregulation by
lipopolysaccharide through reduced promoter activity in cultured rat neocortical astrocytes. J.
Neurosci. Res. 83, 1447-1460.
117. Taniura H., Sng J.C.G. and Yoneda Y. (2006) Histone modifications in status epilepticus inducedby kainate. Histol. Histopathol. 21, 785-791.
118. Taniura H., Ito M., Sanada N., Kuramoto N., Ohno Y., Nakamichi N. and Yoneda Y. (2006)
Chronic vitamin D3 treatment protects against neurotoxicity by glutamate in association withupregulation of vitamin D receptor mRNA expression in cultured rat cortical neurons. J.
Neurosci. Res. 83, 1179-1189.
9119. Sng J.C.G., Taniura H. and Yoneda Y. (2006) Histone modifications in kainate-induced statusepilepticus. Eur. J. Neurosci. 23, 1269-1282.
120. Moriguchi N.*, Hinoi E.*, Tsuchihashi Y., Fujimori S., Iemata M., Takarada T. and Yoneda Y.
(2006) Cytoprotection by pyruvate through an anti-oxidative mechanism in cultured rat calvarial
osteoblasts. Histol. Histopathol. 21, 969-977. *Equally contributed.
121. Hirai T.*, Taniura H.*, Goto Y., Ogura M., Sng J.C.G. and Yoneda Y. (2006) Stimulation ofubiquitin-proteasome pathway through the expression of amidohydrolase for N-terminal
asparagine (Ntan1) in cultured rat hippocampal neurons exposed to static magnetism. J.
Neurochem. 96, 1519-1530. *Equally contributed.
122. Fujimori S., Osawa M., Iemata M., Hinoi E. and Yoneda Y. (2006) Increased GABA transport
activity in rat calvarial osteoblasts cultured under hyperglycemic conditions. Biol. Pharm. Bull.
29, 297-301.
123. Ogita K., Nishiyama N., Sugiyama C., Higuchi K., Yoneyama M. and Yoneda Y. (2005)
Regeneration of granule neurons after lesioning of hippocampal dentate gyrus: evaluation using
adult mice treated with trimethyltin chloride as a model. J. Neurosci. Res. 82, 609-621.
124. Hinoi E., Ohashi R., Miyata S., Kato Y., Iemata M., Hojo H., Takarada T. and Yoneda Y. (2005)
Excitatory amino acid transporters expressed by synovial fibroblasts in rats with collageninduced arthritis. Biochem. Pharmacol. 70, 1744-1755.
125. Platenik J., Balcar V.J., Yoneda Y., Miouduszewska B., Buchal R., Hynek R., Killianek L.,
Kuramoto N., Wilczynski G., Ogita K., Nakamura Y. and Kaczmarek L. (2005) Apparent
presence of Ser133-phosphorylated cyclic AMP response element binding protein (CREB) in
brain mitochondria is due to cross-reactivity of pCREB antibodies with pyruvate dehydrogenase.
J. Neurochem. 95, 1446-1460.
126. Wang L.*, Hinoi E.*, Takemori A., Takarada T. and Yoneda Y. (2005) Abolition of chondralmineralization by group III metabotropic glutamate receptors expressed in rodent cartilage. Br.
J. Pharmacol. 146, 732-743. *Equally contributed.
127. Takano K., Ogura M., Yoneda Y. and Nakamura Y. (2005) Oxidative metabolites are involved inpolyamine-induced microglial cell death. Neuroscience 134, 1123-1131.
128. Kamakura M., Tamaki K., Sakaki T. and Yoneda Y. (2005) Increase of AMPA receptor glutamate
receptor 1 subunit and B-cell receptor associated protein 31 gene expression in hippocampus of
fatigued mice. Neurosci. Lett. 387, 1-4.
129. Sng J.C.G., Taniura H. and Yoneda Y. (2005) Inhibition of histone deacetylation by trichostatin
A intensifies the transcriptions of neuronal c-fos and c-jun genes after kainate stimulation.
Neurosci. Lett. 386, 150-155.
130. Hinoi E.*, Wang L.*, Takemori A. and Yoneda Y. (2005) Functional expression of particularisoforms of excitatory amino acid transporters by rodent cartilage. Biochem. Pharmacol. 70, 7081. *Equally contributed.
131. Wang L.*, Hinoi E.*, Takemori A. and Yoneda Y. (2005) Release of endogenous glutamate by
AMPA receptors expressed in cultured rat costal chondrocytes. Biol. Pharm. Bull. 28, 990-993.
*Equally contributed.
132. Kuramoto N., Kubo K., Ogita K., Platenik J., Balcar V.J., Takarada T., Nakamichi N. and Yoneda
Y. (2005) Nuclear condensation of cyclic AMP responsive element binding protein in murine
discrete brain structures. J. Neurosci. Res. 80, 667-676.
133. Hirai T., Taniura H., Goto Y., Tamaki K., Oikawa H., Kambe Y., Ogura M., Ohno Y., Takarada
T. and Yoneda Y. (2005) Counteraction by repetitive daily exposure to static magnetism againstsustained blockade of N-methyl-D-aspartate receptor channels in cultured rat hippocampal
10neurons. J. Neurosci. Res. 80, 491-500.
134. Nakamichi N. and Yoneda Y. (2005) Functional proteins involved in regulation of intracellular
Ca2+ for drug development: Desensitization of N-methyl-D-aspartate receptor channels. J.
Pharmacol. Sci. 97, 348-350.
135. Ogita K., Okuda H., Watanabe M., Nagashima R., Sugiyama C. and Yoneda Y. (2005) In vivo
treatment with the K+ channel blocker 4-aminopyridine protects against kainate-induced
neuronal cell death through activation of NMDA receptors in murine hippocampus.
Neuropharmacol. 48, 810-821.
136. Nakamichi N.*, Kambe Y.*, Oikawa H., Ogura M., Takano K., Tamaki K., Inoue M., Hinoi E.
and Yoneda Y. (2005) Protection by exogenous pyruvate through a mechanism related tomonocarboxylate transporters against cell death induced by hydrogen peroxide in cultured rat
cortical neurons. J. Neurochem. 93, 84-93. *Equally contributed.
137. Oikawa H., Nakamichi N., Kambe Y., Ogura M. and Yoneda Y. (2005) An increase in
intracellular free calcium ions by nicotinic acetylcholine receptors in a single cultured rat corticalastrocyte. J. Neurosci. Res. 79, 535-544.
138. Takano K., Ogura M., Nakamura Y. and Yoneda Y. (2005) Neuronal and glial responses topolyamines in the ischemic brain. Curr. Neurovasc. Res. 2, 213-223.
139. Hirai T. and Yoneda Y. (2005) Transcriptional regulation of neuronal genes and its effect onneural functions: Gene expression in response to static magnetism in cultured rat hippocampal
neurons. J. Pharmacol. Sci. 98, 219-224.
140. Hinoi E. and Yoneda Y. (2005) Glutamatergic signaling in bone. Yoneda Y. Amino Acid
Signaling 04. pp. 103-121. Research Signpost, Kerala.
141. St'astny F., Tejkalova H., Skuba I., Balcar V.J., Kaiser M. and Yoneda Y. (2005) Quinolinic acid,N-methyl-D-aspartate receptor and schizophrenia: Testing an integrative theory. Yoneda Y.
Amino Acid Signaling 04. pp. 67-83. Research Signpost, Kerala.
142. Acosta G.B., Takarada T. and Yoneda Y. (2005) L-serine in the brain. Yoneda Y. Amino Acid
Signaling 04. pp. 17-31. Research Signpost, Kerala.
143. Ogita K., Nitta Y., Watanabe M., Nakatani Y., Nishiyama N., Sugiyama C. and Yoneda Y. (2004)
In vivo activation of c-Jun N-terminal kinase signaling cascade prior to granule cell death
induced by trimethyltin in the dentate gyrus of mice. Neuropharmacol. 47, 619-630.
144. Takarada T., Hinoi E., Fujimori S., Tsuchihashi Y., Ueshima T., Taniura H. and Yoneda Y. (2004)
Accumulation of [3H]glutamate in cultured rat calvarial osteoblasts. Biochem. Pharmacol. 68,
177-184.
145. Kitayama T., Yoneyama M., Tamaki K. and Yoneda Y. (2004) Regulation of neuronaldifferentiation by N-methyl-D-aspartate receptors expressed in neural progenitor cells isolated
from adult mouse hippocampus. J. Neurosci. Res. 76, 599-612.
146. Takarada T., Hinoi E., Balcar V. J., Taniura H. and Yoneda Y. (2004) Possible expression offunctional glutamate transporters in rat testis. J. Endocrinol. 181, 233-244.
147. Ogita K., Kubo M., Nishiyama N., Watanabe M., Nagashima R. and Yoneda Y. (2004) Enhanced
binding activity of nuclear antioxidant-response element through possible formation of
Nrf2/Fos-B complex after in vivo treatment with kainate in murine hippocampus.
Neuropharmacol. 46, 580-589.
148. Hirai T. and Yoneda Y. (2004) Functional alterations in immature cultured rat hippocampal
neurons after sustained exposure to static magnetic fields. J. Neurosci. Res. 75, 230-240.
149. Yoneyama M., Kitayama T., Taniura H. and Yoneda Y. (2004) Immunohistochemical detection
11

by immersion fixation with Carnoy solution of particular non-N-methyl-D-aspartate receptor
subunits in murine hippocampus. Neurochem. Int. 44, 413-422.
150. Hinoi H., Takarada T., Tsuchihashi Y. and Yoneda Y. (2004) Glutamate transporters as a drug
target. Curr. Drug Targets 4, 211-220.
151. Hirai T., Goto Y., Takarada T., Taniura H. and Yoneda Y. (2004) Modulation by static magnetismof neuronal activity. Biomedical Rev. 15, 21-35.
152. Nakamichi N., Oikawa H., Kambe Y. and Yoneda Y. (2004) Relevant modulation by ferrous ionsof N-methyl-D-aspartate receptors in ischemic brain injuries. Curr. Neurovasc. Res. 1, 429-440.
153. Tsuchihashi Y., Hinoi E. and Yoneda Y. (2004) Pyruvate as an endogenous antioxidant. Recent
Res. Dev. Biophys. Biochem. 4, 1-13.
154. Sng J.C.G., Taniura H. and Yoneda Y. (2004) A tale of early response genes. Biol. Pharm. Bull.
27, 606-612.
155. Hinoi E., Takarada T. and Yoneda Y. (2004) Glutamate signaling system in bone. J. Pharmacol.
Sci. 94, 215-220.
156. Hinoi E., Takarada T., Ueshima T., Tsuchihashi Y. and Yoneda Y. (2004) Glutamate signaling inperipheral tissues. Eur. J. Biochem. 271, 1-13.
157. Inoue K., Kuramoto N., Sugiyama C., Taniura H., Sakata K., Fujinami Y., Ogita K. and Yoneda
Y. (2003) Fos-B expression is required for polyamine-induced increase in nuclear activator
protein-1 DNA binding in discrete structures of murine brain. J. Neurosci. Res. 74, 199-209.
158. Inoue K., Kuramoto N., Takano K., Taniura H., Sakata K., Ogita K., Shirahata A. and Yoneda Y.
(2003) Possible correlation between abilities of a variety of polyamines to increase activator
protein-1 DNA binding and to inhibit [3H]spermidine transport in nuclear fractions of murine
brain. Brain Res. 987, 126-130.
159. Ogita K., Fujinami Y., Kitano M. and Yoneda Y. (2003) Transcription factor activator protein-1
expressed by kainate treatment can bind to the non-coding region of mitochondrial genome inmurine hippocampus. J. Neurosci. Res. 73, 794-802.
160. Takarada T., Balcar V.J., Baba K., Takamoto A., Acosta G. B., Takano K. and Yoneda Y. (2003)
Uptake of [3H]L-serine in rat brain synaptosomal fractions. Brain Res. 983, 36-47.
161. Takano K., Nakamura Y. and Yoneda Y. (2003) Microglial cell death induced by a low
concentration of polyamines. Neuroscience 120, 961-967.
162. Kuramoto N., Inoue K., Takano K., Taniura H., Sakata K., Ogita K. and Yoneda Y. (2003) A
possible novel mechanism underlying temperature-dependent uptake of [3H]spermidine innuclear fractions of murine brain. Brain Res. 981, 78-84.
163. Hinoi E., Fujimori S. and Yoneda Y. (2003) Modulation of cellular differentiation by N-methylD-aspartate receptors in osteoblasts. FASEB J. 17, 1532-1534.
164. Hoshi N., Zhang J.-S., Omaki M., Takeuchi T., Yokoyama S., Wanaverbecq N., Langeberg L.K.,
Yoneda Y., Scott J.D., Brown D.A. and Higashida H. (2003) AKAP150 signaling complex
promotes suppression of the M-current by muscarinic agonists. Nature Neurosci. 6, 564-571.
165. Ogita K., Okuda H., Yamamoto Y., Nishiyama N. and Yoneda Y. (2003) In vivo neuroprotectiverole of NMDA receptors against kainate-induced excitotoxicity in murine hippocampal
pyramidal neurons. J. Neurochem. 85, 1336-1346.
166. Yoneyama M., Kitayama T., Taniura H. and Yoneda Y. (2003) Immersion fixation with Carnoy
solution for conventional immunohistochemical detection of particular N-methyl-D-aspartate
receptor subunits in murine hippocampus. J. Neurosci. Res. 73, 416-426.
12167. Kuramoto N., Gion K., Sanada N. and Yoneda Y. (2003) Xenobiotic response element binding
protein expressed in rat brain. Recent Res. Dev. Biophys. Biochem. 3, 599-611.
168. Kuramoto N., Baba K., Gion K., Sugiyama C., Taniura H. and Yoneda Y. (2003) Xenobiotic
response element binding enriched in both nuclear and microsomal fractions of rat cerebellum.
J. Neurochem. 85, 264-273.
169. Kuramoto N., Inoue K., Gion K., Takano K., Sakata K., Ogita K. and Yoneda Y. (2003)
Modulation of DNA binding of nuclear transcription factors with leucine-zipper motifs byparticular endogenous polyamines in murine central and peripheral excitable tissues. Brain Res.
967, 170-180.
170. Murakami K., Nakamura Y. and Yoneda Y. (2003) Potentiation by ATP of lipopolysaccharidestimulated nitric oxide production in cultured astrocytes. Neuroscience 117, 37-42.
171. Nakamura Y., Omaki M., Murakami K. and Yoneda Y. (2003) Involvement of protein kinase C
in glutamate release from cultured microglia. Brain Res. 962, 122-128.
172. Kitayama T., Yoneyama M. and Yoneda Y. (2003) Possible regulation by N-methyl-D-aspartate
receptors of proliferative progenitor cells expressed in adult mouse hippocampal dentate gyrus.
J. Neurochem. 84, 767-780.
173. Kuramoto N., Goto E., Masamune Y., Gion K. and Yoneda Y. (2002) Existence of xenobiotic
response element binding in Dictyostelium. Biochim. Biophys. Acta - Gene Structure andExpression 1578, 1-11.
174. Nakamichi N., Ohno H., Nakamura Y., Hirai T., Kuramoto N. and Yoneda Y. (2002) Blockade
by ferrous iron of Ca2+ influx through N-methyl-D-aspartate receptor channels in immature
cultured rat cortical neurons. J. Neurochem. 83, 1-11.
175. Hinoi E., Fujimori S., Yoneyama M. and Yoneda Y. (2002) Blockade by N-methyl-D-aspartateof elevation of activator protein-1 binding after stress in rat adrenal gland. J. Neurosci. Res. 70,
161-171.
176. Hinoi E., Fujimori S., Takarada T., Taniura H. and Yoneda Y. (2002) Facilitation of glutamate
release by ionotropic glutamate receptors in osteoblasts. Biochem. Biophys. Res. Commun. 297,452-458.
177. Ohtani K., Tanaka H., Yoneda Y., Yasuda H., Ito A., Nagata R. and Nakamura M. (2002) In vitro
and in vivo antagonistic activities of SM-31900 for the NMDA receptor glycine-binding site.
Brain Res. 944, 165-173.
178. Hinoi E., Fujimori S., Takemori A., Kurabayashi H., Nakamura Y. and Yoneda Y. (2002)
Demonstration of expression of mRNA for particular AMPA and kainate receptor subunits inimmature and mature cultured rat calvarial osteoblasts. Brain Res. 943, 112-116.
179. Hinoi E., Fujimori S., Takemori A. and Yoneda Y. (2002) Cell death by pyruvate deficiency inproliferative cultured calvarial osteoblasts. Biochem. Biophys. Res. Commun. 294, 1177-1183.
180. Fujimori S., Hinoi E. and Yoneda Y. (2002) Functional GABAB receptors expressed in cultured
calvarial osteoblasts. Biochem. Biophys. Res. Commun. 293, 1445-1452.
181. Ogita K., Okuda H., Kitano M., Fujinami Y., Ozaki K. and Yoneda Y. (2002) Localization ofactivator protein-1 complex with DNA binding activity in mitochondria of murine brain after invivo treatment with kainate. J. Neurosci. 22, 2561-2570.
182. Hinoi E., Fujimori S., Nakamura Y., Balcar V.J., Kubo K., Ogita K. and Yoneda Y. (2002)
Constitutive expression of heterologous N-methyl-D-aspartate receptor subunits in rat adrenal
medulla. J. Neurosci. Res. 68, 36-45.
183. Hirai T., Nakamichi N. and Yoneda Y. (2002) Activator protein-1 complex expressed by
13

magnetism in cultured rat hippocampal neurons. Biochem. Biophys. Res. Commun. 292, 200207.
184. Hirai T., Kuramoto N., Maruyama H., Balcar V.J., Nakamura Y. and Yoneda Y. (2002)
Potentiation of nuclear activator protein-1 DNA binding following brief exposure to N-methylD-aspartate in immature cultured rat hippocampal neurons. J. Neurosci. Res. 67, 523-532.
185. Nakamichi N., Manabe T. and Yoneda Y. (2002) Nuclear degradation of particular Fos family
members expressed following injections of NMDA and kainate in murine hippocampus.
Neurochem. Res. 27, 131-138.
186. Takamoto A., Quiggin L.B., Lieb I., Shave E., Balcar V.J. and Yoneda Y. (2002) Differences
between D- and L-aspartate binding to the Na+-dependent binding sites on glutamate transporters
in frozen sections of rat brain. Life Sci. 70, 991-1001.
187. Nakamichi N., Ohno H., Kuramoto N. and Yoneda Y. (2002) Dual mechanisms of Ca2+ increases
elicited by N-methyl-D-aspartate in immature and mature cultured cortical neurons. J. Neurosci.
Res. 67, 275-283.
188. Hinoi E., Balcar V.J., Kuramoto N., Nakamichi N. and Yoneda Y. (2002) Nuclear transcription
factors in the hippocampus. Prog. Neurobiol. 68, 145-165.
189. Nakamichi N. and Yoneda Y. (2002) Transcription factors and drugs in the brain. Jap. J.
Pharmacol. 89, 337-348.
190. Ogita K., Takagi R., Oyama N., Okuda H., Ito F., Okui M., Shimizu N. and Yoneda Y. (2001)
Decrease in level of APG-2, a member of the heat shock protein 110 family, in murine brain
following systemic administration of kainic acid. Neuropharmacol. 41, 285-293.
191. Manabe T., Kuramoto N., Nakamichi N., Aramachi K., Baba K., Hirai T., Yoneyama M. and
Yoneda Y. (2001) Degradation of c-Fos protein expressed by N-methyl-D-aspartic acid in nuclear
fractions of murine hippocampus. Brain Res. 905, 34-43.
192. Manabe T., Ogita K., Nakamichi N. and Yoneda Y. (2001) Differential in vitro degradation ofparticular Fos family members expressed by kainic acid in nuclear and cytosolic fractions ofmurine hippocampus. J. Neurosci. Res. 64, 34-42.
193. Ogita K., Kitayama T., Okuda H. and Yoneda Y. (2001) Effects of glutathione depletion by 2cyclohexen-1-one on excitatory amino acids-induced enhancement of activator protein-1 DNA
binding in murine hippocampus. J. Neurochem. 76, 1905-1915.
194. Hinoi E. and Yoneda Y. (2001) Expression of GluR6/7 subunits of kainate receptors in rat
adenohypophysis. Neurochem. Int. 38, 539-547.
195. Hinoi E., Fujimori S., Nakamura Y. and Yoneda Y. (2001) Group III metabotropic glutamate
receptors in rat cultured calvarial osteoblasts. Biochem. Biophys. Res. Commun. 281, 341-346.
196. Hinoi E., Ogita K., Takeuchi Y., Ohashi H., Maruyama T. and Yoneda Y. (2001) Characterization
with [3H]quisqualate of group I metabotropic glutamate receptor subtype in rat central andperipheral excitable tissues. Neurochem. Int. 38, 277-285.
197. Balcar V.J., Takamoto A. and Yoneda Y. (2001) Neurochemistry of L-glutamate transport in the
CNS: Thirty years of Progress, The Collection of Czechoslovak Chemical Communications 66,
1315-1340.
198. Yoneda Y., Kuramoto N., Kitayama T. and Hinoi E. (2001) Consolidation of transient signals
through nuclear transcription factors in the brain. Prog. Neurobiol. 63, 697-719.
199. Manabe T., Kitayama T., Ogita K. and Yoneda Y. (2000) Differential expression andphosphorylation of particular fos family members by kainate in nuclear and cytosolic fractionsof murine hippocampus. Neuroscience 100, 453-463.
14

200. Hinoi E., Ogita K., Takeuchi Y., Ohashi H., Maruyama T. and Yoneda Y. (2000) Direct
radiolabeling by [3H]quisqualic acid of group I metabotropic glutamate receptor in rat brain
synaptic membranes. Brain Res. 881, 199-203.
201. Yoneda Y., Ogita K., Azuma Y., Kuramoto N., Manabe T. and Kitayama T. (1999) Predominant
expression of nuclear activator protein-1 complex with DNA binding activity following systemic
administration of N-methyl-D-aspartate in dentate granule cells of murine hippocampus.
Neuroscience 93, 19-31.
202. Yoneda Y., Ogita K., Azuma Y., Ikeda M., Tagami H. and Manabe T. (1999) N-methyl-Daspartate signaling to nuclear activator protein-1 through mechanisms different from those forkainate signaling in murine brain. Neuroscience 90, 519-533.
203. St'astny F., Hinoi E., Ogita K. and Yoneda Y. (1999) Ferrous iron modulates quinolinate-mediated[3H]MK-801 binding to rat brain synaptic membranes in the presence of glycine and spermidine.
Neurosci. Lett. 262, 105-108.
204. Okui M., Ide T., Morita K., Funakoshi E., Ito F., Ogita K., Yoneda Y., Kudoh J. and Shimizu N.
(1999) High-level expression of the Mnb/Dyrk1A gene in brain and heart during rat early
development. Genomics 62, 165-171.
205. Ogita K., Shuto M., Manabe T., Kuramoto N. and Yoneda Y. (1999) Preventive effects ofexogenous phospholipases on inhibition by ferrous ions of [3H]MK-801 binding in rat brain
synaptic membranes. Neurochem. Int. 34, 193-201.
206. Ogita K., Shuto M., Kuramoto N., Manabe T., Hinoi E., Kitayama T., Sakata K. and Yoneda Y.
(1999) Differential inhibition by ferrous ions of [3H]MK-801 binding to native N-methyl-Daspartate channel in neonatal and adult rat brains. Brain Res. 818, 548-552.
207. Kitayama T., Ogita K. and Yoneda Y. (1999) Sustained potentiation of AP1 DNA binding is notalways associated with neuronal death following systemic administration of kainic acid in murine
hippocampus. Neurochem. Int. 35, 453-462.
208. Kitayama T., Ogita K., Nomoto M. and Yoneda Y. (1999) Sensitization by prolonged glutathione
depletion of kainic acid to potentiate DNA binding of the nuclear transcription factor activator
protein-1 in murine hippocampus. Neurosci. Lett. 269, 157-160.
209. Azuma Y., Ogita K. and Yoneda Y. (1999) Constitutive expression of cytoplasmic activator
protein-1 with DNA binding activity and responsiveness to ionotropic glutamate signals in themurine hippocampus. Neuroscience 92, 1295-1308.
210. Yoneda Y., Kuramoto N., Azuma Y., Ogita K., Mitani A., Zhang L., Yanase H., Masuda S. andKataoka K. (1998) Possible involvement of activator protein-1 DNA binding in mechanisms
underlying ischemic tolerance in the CA1 subfield of gerbil hippocampus. Neuroscience 86, 7997.
211. Yoneda Y., Kuramoto N., Azuma Y., Inoue K., Ogita K., Mitani A., Yanase H., Masuda S., Zhang
L. and Kataoka K. (1998) Prolongation by bifemelane of potentiation of AP1 DNA binding in
hippocampal CA1 subfield of gerbils with transient forebrain ischemia. J. Neurosci. Res. 51, 574582.
212. Ogita K., Shuto M. and Yoneda Y. (1998) Nitric oxide-independent inhibition by sodium
nitroprusside of the native N-methyl-D-aspartate recognition domain in a manner different fromthat by potassium ferrocyanide. Neurochem. Int. 33, 1-9.

15

213. Kuramoto N., Azuma Y., Inoue K., Ogita K., Mitani A., Zhang L., Yanase H., Masuda S., Kataoka
K. and Yoneda Y. (1998) Correlation between potentiation of AP1 DNA binding and expressionof c-Fos in association with phosphorylation of CREB at serine133 in thalamus of gerbils withischemia. Brain Res. 806, 152-164.
214. Azuma Y., Nishiguchi M., Tagami H., Ogita K. and Yoneda Y. (1999) Possible in vivo crosstalk
between transcription factors with zinc-finger and leucine-zipper motifs in murine peripheral but
not central excitable tissues. Neurochem. Int. 32, 325-336.
215. Nakamura Y., Tsuji K., Shuto M., Ogita K., Yoneda Y., Shimamoto K., Shibata T. and Kataoka
K. (1997) Protection by diphenyliodonium against glutamate neurotoxicity due to blocking of Nmethyl-D-aspartate receptors. Neuroscience 76, 459-466.
216. Yoneda Y., Azuma Y., Inoue K., Ogita K., Mitani A., Zhang L., Masuda S., Higashihara M. andKataoka K. (1997) Positive correlation between prolonged potentiation of binding of doublestranded oligonucleotide probe for the transcription factor AP1 and resistance to transient
forebrain ischemia in gerbil hippocampus. Neuroscience 79, 1023-1037.
217. Shuto M., Ogita K. and Yoneda Y. (1997) Modulation by both diphenyliodonium anddiphenyleneiodonium of [3H]MK-801 binding to rat brain synaptic membranes. Neurochem. Int.
31, 73-82.
218. Shuto M., Ogita K., Minami T., Maeda H. and Yoneda Y. (1997) Inhibition of [3H]MK-801
binding by ferrous (II) but not ferric (III) ions in a manner different from that by sodium
nitroprusside (II) in rat brain synaptic membranes. J. Neurochem. 69, 744-752.
219. Ogita K., Amizuka T., Azuma Y. and Yoneda Y. (1996) Differentiation by magnesium ions ofaffinities of nuclear proteins for consensus core nucleotide element of the transcription factor cMyc in murine brain. Neurochem. Res. 21, 201-209.
220. Enomoto R., Ogita K., Kawanami K., Azuma Y. and Yoneda Y. (1996) Simultaneous
determination of binding of a variety of radioligands related to ionotropic excitatory amino acidreceptors in fetal and neonatal rat brains. Brain Res. 723, 100-109.
221. Azuma Y., Ogita K. and Yoneda Y. (1996) Particular nuclear transcription factors responsive tosystemic administration of kainic acid in murine brain. Neurochem. Int. 29, 289-299.
222. Azuma Y., Ogita K. and Yoneda Y. (1996) Binding of double stranded oligonucleotide probes
for particular transcription factors with leucine-zipper motifs in discrete brain structures of micewith acquired and inherent spontaneous seizures. Neurochem. Int. 29, 323-333.
223. Yoneda Y., Ogita K., Enomoto R., Kojima S., Shuto M., Shirahata A. and Samejima K. (1995)
Search for novel ligands selective at a polyamine recognition domain on the N-methyl-D-aspartate
receptor complex using membrane binding techniques. Brain Res. 679, 15-24.
224. Yoneda Y., Han D., Ogita K. and Watanabe A. (1995) Distinction between binding of[3H]triamcinolone acetonide to a ligand binding domain on the glucocorticoid receptor complex
in cytosol fractions of brain and liver from the rat with intact adrenals. Brain Res. 685, 105-116.
225. Ogita K. and Yoneda Y. (1995) Detection of DNA binding activities of transcription factors withdifferent protein motifs in nuclear extracts of murine brain by using gel-retardationelectrophoresis. J. Neurochem. 64, 1431-1439.
226. Ogita K., Enomoto R., Nakahara F., Ishitsubo N. and Yoneda Y. (1995) A possible role ofglutathione as an endogenous agonist at the N-methyl-D-aspartate recognition domain in rat brain.
J. Neurochem. 64, 1088-1096.
16

227. Nakanishi H., Katsuta K., Ueda Y., Takasugi H., Kuno A., Ohkubo M., Ogita K., Yoneda Y.,
Shirakawa K. and Yoshida K. (1995) Behavioral studies on FR115427, a novel selective Nmethyl-D-aspartate antagonist. Psychopharmacology (Berl) 117, 172-177.
228. Kitaichi K., Yamada K., Yoneda Y., Ogita K., Hasegawa T., Furukawa H. and Nabeshima T.
(1995) Risperidone prevents the development of supersensitivity, but not tolerance, tophencyclidine in rats treated with subacute phencyclidine. Life Sci. 56, 531-543.
229. Han D., Ogita K. and Yoneda Y. (1995) Potentiation by calcium ions of [3H]MK-801 binding toan ion channel associated with the N-methyl-D-aspartate receptor complex in rat brain.
Neurochem. Int. 26, 59-68.
230. Yoneda Y., Suzuki T. and Ogita K. (1994) Differential profiles of binding of a radiolabeledagonist and antagonist at a glycine recognition domain on the N-methyl-D-aspartate receptor
ionophore complex in rat brain. J. Neurochem. 62, 102-112.
231. Yoneda Y., Ogita K., Inoue K., Mitani A., Zhang L., Masuda S., Higashihara M. and Kataoka K.
(1994) Rapid potentiation of DNA binding activities of particular transcription factors withleucine-zipper motifs in discrete brain structures of the gerbil with transient forebrain ischemia.
Brain Res. 667, 54-66.
232. Yoneda Y. and Ogita K. (1994) Rapid and selective enhancement of DNA binding activity of thetranscription factor AP1 by systemic administration of N-methyl-D-aspartate in murine
hippocampus. Neurochem. Int. 25, 263-271.
233. Yoneda Y., Han D. and Ogita K. (1994) Preferential induction by stress of the N-methyl-Daspartate recognition domain in discrete structures of rat brain. J. Neurochem. 63, 1863-1871.
234. Yoneda Y., Enomoto R., Ogita K., Kabuto H. and Mori A. (1994) Possible dysfunction ofionotropic glutamate receptors in cerebellum of epileptic E1 mouse brain. Neurochem. Int. 25,
273-285.
235. Yoneda Y., Enomoto R. and Ogita K. (1994) Supporting evidence for negative modulation by
protons of an ion channel associated with the N-methyl-D-aspartate receptor complex in rat brain
using ligand binding techniques. Brain Res. 636, 298-307.
236. Ogita K. and Yoneda Y. (1994) Partial purification of [3H]glutamate-associating-proteins withsensitivity to displacement by N-methyl-D-aspartate from rat brain. Neurochem. Int. 25, 111-121.
237. Ogita K. and Yoneda Y. (1994) Selective potentiation of DNA binding activities of both activator
protein 1 and cyclic AMP response element binding protein through in vivo activation of Nmethyl-D-aspartate receptor complex in mouse brain. J. Neurochem. 63, 525-534.
238. Ogita K., Sakamoto T., Han D., Azuma Y. and Yoneda Y. (1994) Discrimination by added ionsof ligands at ionotropic excitatory amino acid receptors insensitive to N-methyl-D-aspartate in rat
brain using membrane binding techniques. Neurochem. Int. 24, 379-388.
239. Nagata R., Tanno N., Kodo T., Ae N., Yamaguchi H., Nishimura T., Antoku F., Tatsuno T., Kato
T., Tanaka Y., Nakamura M., Ogita K. and Yoneda Y. (1994) Tricyclic quinoxalinediones: 5,6dihydro-1H-pyrrolo[1,2,3-de] quinoxaline-2,3-diones and 6,7-dihydro-1H,5H-pyrido[1,2,3-de]quinoxaline-2,3-diones as potent antagonists for the glycine binding site of the NMDA receptor.
J. Med. Chem. 37, 3956-3968.
240. Han D., Ogita K., Kashiwai K., Narita S. and Yoneda Y. (1994) Binding of [3H]triamcinolone
acetonide to glucocorticoid receptors in brain cytosol fractions of rats with intact adrenals.
Neurochem. Int. 24, 339-348.
17241. Zuo P., Ogita K., Suzuki T., Han D. and Yoneda Y. (1993) Further evidence for multiple formsof an N-methyl-D-aspartate recognition domain in rat brain using membrane binding techniques.
J. Neurochem. 61, 1865-1873.
242. Zuo P., Ogita K., Han D. and Yoneda Y. (1993) Comparative studies on binding of 3 different
ligands to the N-methyl-D-aspartate recognition domain in brain synaptic membranes treated with
Triton X-100. Brain Res. 609, 253-261.
243. Yoneda Y., Suzuki T., Ogita K., Katoh T., Tanaka H., Maruoka Y. and Nakamura M. (1993)
Excitatory amino acid receptor binding in hippocampus of gerbils with transient global brainischemia. Brain Res. 613, 21-31.
244. Yoneda Y., Suzuki T., Ogita K. and Han D. (1993) Support for radiolabeling of a glycine
recognition domain on the N-methyl-D-aspartate receptor ionophore complex by 5,7[3H]dichlorokynurenate in rat brain. J. Neurochem. 60, 634-645.
245. Yoneda Y., Ogita K., Kabuto H. and Mori A. (1993) Selectively high expression of thetranscription factor AP1 in telencephalic structures of epileptic E1 mice. Neurosci. Lett. 161, 161164.
246. Suzuki T., Ogita K. and Yoneda Y. (1993) Potentiation by polyamines of an interaction of
noncompetitive antagonists at the N-methyl-D-aspartate receptor ionophore complex withphosphatidylserine. Neurochem. Int. 23, 427-440.
247. Kataoka K., Mitani A., Andou Y., Enomoto R., Ogita K. and Yoneda Y. (1993) Binding of[3H]MK-801, NMDA-displaceable [3H]glutamate, [3H]glycine, [3H]spermidine, [3H]kainate and[3H]AMPA to regionally discrete brain membranes of the gerbil: a biochemical study.
Neurochem. Int. 22, 37-43.
248. Enomoto R., Ogita K. and Yoneda Y. (1993) Multiplicity of [3H]1,3-di-o-tolylguanidine bindingsites with low affinity for haloperidol in rat brain. Biol. Pharm. Bull. 16, 989-996.
249. Enomoto R,. Ogita K., Han D. and Yoneda Y. (1993) Differential potentiation by spermidine ofabilities of a variety of displacers for [3H]MK-801 binding in hippocampal synaptic membranes.
Neurosci. Res. 16, 217-224.
250. Zuo P., Ogita K. and Yoneda Y. (1992) Presence of the binding of a variety of ligands related toionotropic excitatory amino acid receptors in rat retina. Brain Res. 576, 168-172.
251. Yoneda Y. and Ogita K. (1992) Attempts to isolate the NMDA receptor complex from rat brain.
Mol. Neuropharmacol. 2, 65-70.
252. Tamaru M., Yoneda Y., Ogita K., Shimizu J., Matsutani T. and Nagata Y. (1992) Excitatory
amino acid receptors in brains of rats with methylazoxymethanol-induced microencephaly.
Neurosci. Res. 14, 13-25.
253. Ogita K., Suzuki T., Ping-ping Z. and Yoneda Y. (1992) Inhibition by calmodulin antagonists of[3H]MK-801 binding in brain synaptic membranes. J. Neurochem. 59, 1008-1016.
254. Ogita K., Ohkawara A., Suzuki T., Ohgaki T., Uchida S., Meguri H. and Yoneda Y. (1992) Effects
of ifenprodil on the N-methyl-D-aspartate receptor ionophore complex in rat brain. Neurochem.
Int. 21, 135-147.
255. Enomoto R., Ogita K., Han D. and Yoneda Y. (1992) Differential modulation by divalent cationsof [3H]MK-801 binding in brain synaptic membranes. J. Neurochem. 59, 473-481.

18

256. Akiyama K., Yoneda Y., Ogita K., Itoh T., Daigen A., Sora I., Kohira I., Ujike H. and Otsuki S.
(1992) Ionotropic excitatory amino acid receptors in discrete brain regions of kindled rats. Brain
Res. 587, 73-82.
257. Yoneda Y., Ogita K., Enomoto R., Suzuki T. and Kito S. (1991) Identification andcharacterization of specific binding sites of [ 3H]spermidine in synaptic membranes of rat brain.
Brain Res. 563, 17-27.
258. Yoneda Y., Ogita K. and Enomoto R. (1991) Characterization of spermidine-dependent [3H](+)5-methyl-10,11-dihydro-5H-dibenzo[a,d]cyclohepten-5,10-imine (MK-801) binding in brain
synaptic membranes treated with Triton X-100. J. Pharmacol. Exp. Ther. 256, 1161-1172.
259. Yoneda Y. and Ogita K. (1991) Heterogeneity of the N-methyl-D-aspartate receptor ionophore
complex in rat brain, as revealed by ligand binding techniques. J. Pharmacol. Exp. Ther. 259,
86-96.
260. Yoneda Y. and Ogita K. (1991) Inhibitory modulation by sodium ions of the N-methyl-Daspartate recognition site in brain synaptic membranes. J. Neurochem. 57, 2036-2046.
261. Tamaru M., Yoneda Y., Ogita K., Shimizu J. and Nagata Y. (1991) Age-related decreases of the
N-methyl-D-aspartate receptor complex in the rat cerebral cortex and hippocampus. Brain Res.
542, 83-90.
262. Ogita K., Kouda T., Suzuki T., Ohkawara A., Enomoto R., Nabeshima T. and Yoneda Y. (1991)
Differential effects of SH-reactive agents on [3H](+/-)-3-(2-carboxypiperazin-4-yl)propyl-1phosphonate and [3H]glutamate binding in brain synaptic membranes treated with triton X-100.
Neurochem. Int. 18, 55-62.
263. Ogita K., Suzuki T., Han D. and Yoneda Y. (1991) Solubilization studies on the N-methyl-Daspartate receptor ionophore complex in rat brain. Neuro Chem (Life Sci Adv) 10, 125-136.
264. Nabeshima T., Katoh A., Ishimaru H., Yoneda Y., Ogita K., Murase K., Ohtsuka H., Inari K.,
Fukuta T. and Kameyama T. (1991) Carbon monoxide-induced delayed amnesia, delayed
neuronal death and change in acetylcholine concentration in mice. J. Pharmacol. Exp. Ther. 256,378-384.
265. Yoneda Y. and Ogita K. (1990) Biochemical and pharmacological properties of NMDA receptor
ion channels in rat brain. Pharmacol. 9, 167-182.
266. Yoneda Y., Ogita K., Suzuki T., Enomoto R., Zuo P. (1990) Competitive inhibition of NMDAmediated responses by guanine nucleotides in brain synaptic membranes treated with Triton X100. Neurosci. Res. 9, 114-125.
267. Yoneda Y., Ogita K. and Suzuki T. (1990) Interaction of strychnine-insensitive glycine binding
with MK-801 binding in brain synaptic membranes. J. Neurochem. 55, 237-244.
268. Yoneda Y., Ogita K., Kouda T. and Ogawa Y. (1990) Radioligand labeling of N-methyl-Daspartic acid (NMDA) receptors by [3H](+-)-3-(2-carboxypiperazin-4-yl)propyl-1-phosphonicacid in brain synaptic membranes treated with Triton X-100. Biochem. Pharmacol. 39, 225-228.
269. Ogita K. and Yoneda Y. (1990) 6,7-Dichloroquinoxaline-2,3-dione is a competitive antagonist
specific to strychnine-insensitive [3H]glycine binding sites on the N-methyl-D-aspartate receptor
complex. J. Neurochem. 54, 699-702.
270. Ogita K. and Yoneda Y. (1990) Temperature-independent binding of [3H](+-)-3-(2carboxypiperazin-4-yl) propyl-1-phosphonic acid in brain synaptic membranes treated by Triton
X-100. Brain Res. 515, 51-56.
19

271. Ogita K. and Yoneda Y. (1990) Solubilization of spermidine-sensitive (+)-[3H]5-methyl-10, 11dihydro-5H-dibenzo [a,d] cyclohepten-5, 10-imine ([3H]MK-801) binding activity from rat brain.
J. Neurochem. 55, 1515-1520.
272. Ogita K., Suzuki T., Enomoto R., Ohgaki T., Katagawa J., Uchida S., Meguri H. and Yoneda Y.
(1990) Profiles of [3H]N-[1-(2-thienyl)cyclohexyl]piperidine binding in brain synaptic
membranes treated with Triton X-100. Neurosci. Res. 9, 35-47.
273. Ogita K., Nabeshima T. and Yoneda Y. (1990) [3H]thienylcyclohexylpiperidine binding activity
in brain synaptic membranes treated with Triton X-100. J. Neurochem. 55, 1639-1646.
274. Yoneda Y., Ogita K., Yamada K., Kouda T., Ohgaki T., Uchida S. and Meguri H. (1989) Highconcentrations of calmodulin antagonists inhibit accumulation and binding activities of[3H]glutamate in rat brain. Neurochem. Int. 15, 17-23.
275. Yoneda Y., Ogita K., Ohgaki T., Uchida S. and Meguri H. (1989) N-methyl-D-aspartate-sensitive[3H]glutamate binding sites in brain synaptic membranes treated with Triton X-100. Biochim
Biophys Acta 1012, 74-80.
276. Yoneda Y. and Ogita K. (1989) Characterization of quisqualate-sensitive [3H]glutamate binding
activity solubilized from rat adrenal. Neurochem. Int. 15, 137-143.
277. Yoneda Y. and Ogita K. (1989) Microbial methodological artifacts in [ 3H]glutamate receptor
binding assays. Anal. Biochem. 177, 250-255.
278. Yoneda Y. and Ogita K. (1989) Solubilization of quisqualate-sensitive [3H]glutamate binding
activity from rat retina. J. Neurochem. 52, 1501-1507.
279. Yoneda Y. and Ogita K. (1989) Solubilization of stereospecific and quisqualate-sensitive activityof [3H]glutamate binding in the pituitary of the rat. Neuropharmacology 28, 611-616.
280. Yoneda Y. and Ogita K. (1989) Labeling of NMDA receptor channels by [3H]MK-801 in brain
synaptic membranes treated with Triton X-100. Brain Res. 499, 305-314.
281. Yoneda Y. and Ogita K. (1989) Abolition of the NMDA-mediated responses by a specific glycine
antagonist, 6,7-dichloroquinoxaline-2,3-dione (DCQX). Biochem. Biophys. Res. Commun. 164,841-849.
282. Ogita K. and Yoneda Y. (1989) Selective potentiation by L-cysteine of apparent binding activityof [3H]glutathione in synaptic membranes of rat brain. Biochem. Pharmacol. 38, 1499-1505.
283. Ogita K., Suzuki T. and Yoneda Y. (1989) Strychnine-insensitive binding of [3H]glycine tosynaptic membranes in rat brain, treated with Triton X-100. Neuropharmacology 28, 1263-1270.
284. Ohgaki T., Uchida S., Meguri H., Ogita K. and Yoneda Y. (1988) Preventive action of quisqualic
acid against grayanotoxin-induced suppression of locomotor activity in mice.
Neuropharmacology 27, 1045-1053.
285. Ogita K. and Yoneda Y. (1988) Disclosure by triton X-100 of NMDA-sensitive [3H] glutamate
binding sites in brain synaptic membranes. Biochem. Biophys. Res. Commun. 153, 510-517.
286. Ogita K. and Yoneda Y. (1988) Temperature-dependent and -independent apparent binding
activities of [3H]glutathione in brain synaptic membranes. Brain Res. 463, 37-46.
287. Ogita K., Ogawa Y. and Yoneda Y. (1988) Apparent binding activity of [3H]glutathione in rat
central and peripheral tissues. Neurochem. Int. 13, 493-497.
288. Ohgaki T., Meguri H., Ogita K. and Yoneda Y. (1987) Tetrodotoxin-insensitive central depression
by grayanotoxin-III in mice. Brain Res. 425, 364-368.
20

289. Ogita K. and Yoneda Y. (1987) Possible presence of [3H]glutathione (GSH) binding sites insynaptic membranes from rat brain. Neurosci. Res. 4, 486-496.
290. Nakamuta H., Ogita K., Fukuda Y., Koida M. and Yoneda Y. (1987) Characterization of[3H]glutamate binding sites on frozen sections from rat adrenal. Neurochem. Int. 10, 565-570.
291. Yoneda Y. and Ogita K. (1987) Are Ca2+-dependent proteases really responsible for Cl -dependent and Ca2+-stimulated binding of [3H]glutamate in rat brain? Brain Res. 400, 70-79.
292. Yoneda Y. and Ogita K. (1987) Enhancement of [3H]glutamate binding by N-methyl-D-aspartic
acid in rat adrenal. Brain Res. 406, 24-31.
293. Yoneda Y. and Ogita K. (1987) Solubilization of novel binding sites for [ 3H]glutamate in rat
adrenal. Biochem. Biophys. Res. Commun. 142, 609-616.
294. Yoneda Y., Ogita K., Nakamuta H., Fukuda Y., Koida M. and Ogawa Y. (1987) Comparative
study of [3H]glutamate binding sites in rat retina and cerebral cortex. Biochem. Pharmacol. 36,
772-774.
295. Ogita K., Kitago T., Nakamuta H., Fukuda Y., Koida M., Ogawa Y. and Yoneda Y. (1986)
Glutathione-induced inhibition of Na+-independent and -dependent bindings of L-[3H]glutamate
in rat brain. Life Sci. 39, 2411-2418.
296. Ogita K. and Yoneda Y. (1986) Characterization of Na+-dependent binding sites of [3H]glutamate
in synaptic membranes from rat brain. Brain Res. 397, 137-144.
297. Ogita K. and Yoneda Y. (1986) Differentiation of the Ca2+-stimulated binding from the Cl- dependent binding of [3H]glutamate in synaptic membranes from rat brain. Neurosci. Res. 4, 129142.
298. Yoneda Y., Ogita K., Nakamuta H., Koida M., Ohgaki T. and Meguri H. (1986) Possible
interaction of [3H]glutamate binding sites with anion channels in rat neural tissues. Neurochem.
Int. 9, 521-531.
299. Yoneda Y. and Ogita K. (1986) [3H]glutamate binding sites in the rat pituitary. Neurosci. Res. 3,
430-435.
300. Yoneda Y. and Ogita K. (1986) Localization of [3H]glutamate binding sites in rat adrenal medulla.
Brain Res. 383, 387-391.
301. Yoneda Y., Kuriyama K. and Takahashi M. (1985) Modulation of synaptic GABA receptor
binding by membrane phospholipids: possible role of active oxygen radicals. Brain Res. 333,
111-122.
302. Yoneda Y., Kanmori K., Takahashi M., Zuo P.P., Paik I.H. and Kuriyama K. (1984) Preferential
release of newly synthesized [3H]GABA from striatal slices to preloaded [3H]GABA. Neurochem.
Int. 6, 641-649.
303. Takahashi M., Yoneda Y. and Kuriyama K. (1984) Enhancement of gamma-aminobutyric acid
(GABA) receptor binding by lipophilic antioxidants. Brain Res. 296, 164-167.
304. Kuriyama K., Kanmori K. and Yoneda Y. (1984) Preventive effect of alcohol against stressinduced alteration in content of monoamines in brain and adrenal gland. Neuropharmacology 23,649-654.
305. Kuriyama K., Kanmori K., Taguchi J. and Yoneda Y. (1984) Stress-induced enhancement ofsuppression of [3H]GABA release from striatal slices by presynaptic autoreceptor. J. Neurochem.
42, 943-950.
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306. Kuriyama K., Yoneda Y., Taguchi J., Takahashi M. and Ohkuma S. Properties of purifiedγaminobutyric acid (GABA) receptor and modulation of GABA receptor by membrane
phospholipids. Neuropharmacology 23, 839-840.
307. Yoneda Y., Kanmori K., Ida S. and Kuriyama K. (1983) Stress-induced alterations in metabolismof γ-aminobutyric acid in rat brain. J. Neurochem. 40, 350-356.
308. Tokunaga H., Yoneda Y. and Kuriyama K. (1983) Streptozotocin-induced elevation of pancreatictaurine content and suppressive effect of taurine on insulin secretion. Eur. J. Pharmacol. 87, 237243.
309. Yoneda Y. and Roberts E. (1982) A new synaptosomal biosynthetic pathway of proline fromornithine and its negative feedback inhibition by proline. Brain Res. 239, 479-488.
310. Yoneda Y., Roberts E. and Dietz GW, Jr. (1982) A new synaptosomal biosynthetic pathway of
glutamate and GABA from ornithine and its negative feedback inhibition by GABA. J.
Neurochem. 38, 1686-1694.
311. Yoneda Y. and Kuriyama K. (1980) Presence of a low molecular weight endogenous inhibitor on
3
H -muscimol binding in synaptic membranes. Nature 285, 670-673.
312. Yoneda Y. and Kuriyama K. (1980) Some characteristics of [3H]muscimol binding to synaptic
membrane from rat brain. Brain Res. 197, 554-560.
313. Kuriyama K., Kurihara E., Ito Y. and Yoneda Y. (1980) Increase in striatal [3H]muscimol binding
following intrastriatal injection of kainic acid: a denervation supersensitivity phenomenon. J.
Neurochem. 35, 343-348.
314. Kurihara E., Kuriyama K. and Yoneda Y. (1980) Interconnection of GABA-ergic neurons in rat
extrapyramidal tract: analysis using intracerebral microinjection of kainic acid. Exp. Neurol. 68,
12-26.
315. Tokunaga H., Yoneda Y. and Kuriyama K. (1979) Protective actions of taurine against
streptozotocin-induced hyperglycemia. Biochem. Pharmacol. 28, 2807-2811.
316. Yoneda Y. and Kuriyama K. (1978) A comparison of microdistributions of taurine and cysteine
sulphinate decarboxylase activity with those of GABA and L-glutamate decarboxylase activity in
rat spinal cord and thalamus. J. Neurochem. 30, 821-825.
317. Kuriyama K. and Yoneda Y. (1978) Morphine induced alterations ofγ-aminobutyric acid andtaurine contents and L-glutamate decarboxylase activity in rat spinal cord and thalamus: possible
correlates with analgesic action of morphine. Brain Res. 148, 163-179.
318. Yoneda Y., Takashima S., Hirai K., Kurihara E., Yukawa Y., Tokunaga H. and Kuriyama K.
(1977) Microassay methods for taurine and cysteine sulfinate decarboxylase activity. Jpn. J.
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