Eugene Consulting Inc.
111 St. Clair Ave W
Toronto, ONM4V 1N5

August/September 2019 Report
Updated Information on 23 and Me- DNA testing and genetic testing in general is an inexact sicenethat is prone to errors, therefore, the results from the test are
not always accurate- The ancestry component of the 23 and Me test is based on selfreported surveys → leads to inaccuracy- Europeans are much more represented in DNA databases- Nearly all genetic testing companies reserve the right to change
their privacy policies at any time
- Companies like 23andMe and Ancestry have signed on to a listof best practices (a policy framework created by the Future ofPrivayc Forum which includes both consumer and industry
privacy groups)
o While this is comforting, these practices are not legally
mandated- Some law enforcements use DNA test results gathered by thesecompanies to help investigate crimes- When GEDMatch changed it settings so that users have to opt
in to law enforcement searches, they available database shrunkfrom over a million to just 180,000 profiles- Companies with fewer than 15 people, life insurance, disability
insurance, and long-term care insurance companies canrequest genetic testing as part of their application process
Ferticility start-up Celmatix sues former business partner 23andMe- Dec 10, 2019https://www.cnbc.com/2019/12/10/celmatix-sues-23andme-for-100million.html

Eugene Consulting Inc.
111 St. Clair Ave W
Toronto, ONM4V 1N5- 23andMe is getting sued for over $100 million in damages byCelmatix- Celmatix alleges that 23andMe breached a research contractthat it entered into in November 2015 and caused the,significant financial setbacks- The 2 companies forged plans to create a “general fertilityprognosis product” aimed at helping women proactively plan
the optimal time to start a familyo The deal also included an exclusive agreement where23andMe would not be able to work with rival companies
in the fertility and infertility space for a decade- However, in 2018, 23andMe asked Celmatix to terminate thedeal and its exclusivity- Celmatix also alleges that 23andMe made steps to thwart
Celmatix’ financing round, causing the company great financial
loss
https://www.darkdaily.com/23andme-invites-customers-to-addhealth-and-drug-data-to-stored-genetic-test-results-encroachingon-markets-where-both-apple-and-clinical-laboratories-generaterevenue/
December 27, 2019- 23andMe is beta testing a method for combining customers’
private health data (clinical laboratory test results andprescription drug usage) with their genetic data to create thelargest database of its kindo This would place 23andMe in a unique market position
that even Apple Health cannot yet claim → apple does nothave genetic data

Eugene Consulting Inc.
111 St. Clair Ave W
Toronto, ONM4V 1N5

o This may also make medical laboratories consider
23andMe’s move a competitive threat to their own efforts
to capitalize on combining lab results with patients’
medical histories, drug profiles, and demographic data
- 23andMe plans to use 3rd party medical network Human API tocollect and manage the datao https://www.humanapi.co- Involvement in this beta test is voluntary- 23andMe is hoping that after people receive their genetic test
results, they will then elect to add their clinical laboratory
results, medical histories, and prescription drug information totheir accounts as wello They market that this will provide customers with easy,
integrated access to health data that is typically scatteredacross multiple systems, and to assist with medical searcho This extra information could also help 23andMe provide
customers with information about their risks for complex,
chronic ailments
HumanAPI (https://www.humanapi.co)
Company mission/goal- Mission: to create health data liquidity valued by customers,
controlled by consumers
o To create a new kind of consumer-centric healthecosystem that give companies a simple way to getconsumers to share their health data, so better products
and services can be built- The company built manual integrations to thousands offragmented health information systems in the U.S and created aEugene Consulting Inc.
111 St. Clair Ave W
Toronto, ONM4V 1N5---

new way for people to exchange and use the health data theyneed
Investors: Bluerun Ventures, Andreessen Horowitz, SciFi VC
The platform allows consumers to find, connect, and manage
their healthdata → by singing up for a Human API accounto They can search their doctors and health systems andlocate their patient portal accounts using theirProviderGraph technology and consolidate their healthdata sourceso They can also add data from fitness devices and sync all of
their health data
From the platform consumers can:o Add new sources
o Turn off the continuous sync for any given source
o Manage who has access to their health data and what data
they have access to
There is a mobile app
264M users
Over 20,000 data sources in networko Includes data from
▪ EHRS▪ Health systems▪ Hospitals and Doctors▪ Health insurers▪ Laboratories▪ Pharmacies▪ Health apps
▪ Medical devices▪ Wearable devices▪ Wellness/fitness apps

Eugene Consulting Inc.
111 St. Clair Ave W
Toronto, ONM4V 1N5- Their unified API allows for a comprehensive, holistic view
- Consumers can add information such as:o Immunizationso Medical conditionso Medicationso Demographic datao Medical procedures performedo Care planso Lab resultso Social historieso Allergieso Vital sign measurementso Doctor instructionso Provider information- The platform helps consumers digest the data in a way thatmakes sense to them
- Key features:

Eugene Consulting Inc.
111 St. Clair Ave W
Toronto, ONM4V 1N5- The API gives developers the ability to quickly use all theconnected data programmatically- Developers can integrate HUmanAPI’s API into their app andallow users to share their health data with them

- Guardian (https://www.guardian-ida-pharmacies.ca) uses
Human API to accelterate insurance underwritingo By engaging with customers to electronically share theirhealth data, Guardian is able to streamline underwriting,
improve customer satisfaction, and differentiatethemselves in the insurance space
Clinical Research- Human API can also help companies streamline clinical trial
recruitment and create digital patient registries
o Can build digital patient registries power by real-world
clinical and claims data

Eugene Consulting Inc.
111 St. Clair Ave W
Toronto, ON
M4V 1N5- This could be one solution for sponsors, CROs, and clinical trial
recruitment as it centralizes patient data and allows for a realtime medical data pipeline- The Health eHeart Study at UCSF is powered by Human API
o UCSF embedded Human API into their Health eHeartstudy, enabling more than 200,000 patients from aroundthe country to share their health records and device data

Eugene Consulting Inc.
111 St. Clair Ave W
Toronto, ONM4V 1N5

Health Plans

Security- The company declares that they only share personal healthdata with companies that consumers trust → will never send
identifiable health data to a third party without consent- Consumers can connect and disconnect any data sources,
authorize or revoke access to any company, save or delete theirhealth data
- Their secure cloud is HIPAA-compliant- Personal data is encrypted both in transit and at rest
- Employees undergo comprehensive background checks- Internal processes are regularly monitored and audited- The platform has completed an independent SOC 2 Type 2
audit → indicates that system is designed to keep data secure