放射線療法

Question

PubMed検索式((("Breast Neoplasms/radiotherapy"[Mesh] OR ("Breast Neoplasms/therapy"[Mesh] AND"Radiotherapy"[Mesh])) AND ("Breast Neoplasms/surgery"[Mesh] OR "Mastectomy"[Mesh]) AND

総説1

乳癌放射線療法の基本"Radiotherapy/adverse effects"[Mesh]) OR ((Breast*[TI] OR Mammary[TI]) AND (Tumo*[TI] OR
Cancer*[TI] OR Carcinoma*[TI] OR Neoplasm*[TI]) AND (radiotherapy[TI] OR radiation[TI] OR
irradiation[TI]) AND (Segmental[TIAB] OR conserv*[TIAB] OR preserv*[TIAB]) AND (risk[TI] OR
effect*[TI]))) AND 2016/1:2021/3[DP] AND (JAPANESE[LA] OR ENGLISH[LA])((("Breast Neoplasms/radiotherapy"[Mesh] OR ("Breast Neoplasms/therapy"[Mesh] AND"Radiotherapy"[Mesh])) AND ("Breast Neoplasms/surgery"[Mesh] OR "Mastectomy"[Mesh]) AND

総説2

乳房手術後に放射線療法が勧められない場合"Contraindications"[Mesh]) OR ((Breast*[TI] OR Mammary[TI]) AND (Tumo*[TI] OR Cancer*[TI] OR
Carcinoma*[TI] OR Neoplasm*[TI]) AND (radiotherapy[TI] OR radiation[TI] OR irradiation[TI]) AND(Segmental[TIAB] OR conserv*[TIAB] OR preserv*[TIAB]) AND contraindicat*[TIAB])) AND
2016/1:2021/3[DP] AND (JAPANESE[LA] OR ENGLISH[LA])((("Breast Neoplasms/radiotherapy"[Mesh] OR ("Breast Neoplasms/therapy"[Mesh] AND"Radiotherapy"[Mesh])) AND "Mastectomy, Segmental"[Mesh] AND ("Neoplasm Staging"[Mesh] OR"Neoplasm Grading"[Mesh] OR "Neoplasm Invasiveness"[Mesh])) OR ((Breast[TI] OR Mammary[TI])

BQ1

Stage I-II乳癌に対する乳房部分切除術後の放射線療法として全乳房照射は勧められるか？

AND (Tumo*[TI] OR Cancer*[TI] OR Carcinoma*[TI] OR Neoplasm*[TI]) AND (Radiotherapy[TI] OR
radiation[TI] OR irradiation[TI]) AND (Conserv*[TIAB] OR Spar*[TIAB] OR Preserv*[TIAB] OR
Segment*[TIAB]) AND (surgery[TI] OR surgical[TI] OR mastectom*[TI] OR resection*[TI] OR
operat*[TI]) AND ("stage I"[TIAB] OR "stage 1"[TIAB] OR "stage I-"[TIAB] OR "stage II"[TIAB] OR"stage 2"[TIAB] OR "stage II-"[TIAB] OR early[ALL]))) AND 2016/1:2021/3[DP] AND (JAPANESE[LA]OR ENGLISH[LA])((("Carcinoma, Intraductal, Noninfiltrating/radiotherapy"[Mesh] OR ("Carcinoma, Intraductal,
Noninfiltrating/therapy"[Mesh] AND "Radiotherapy"[Mesh])) AND "Mastectomy, Segmental"[Mesh])

BQ2

非浸潤性乳管癌に対して乳房部分切除術後に放射線療法は勧められるか。

OR (("Intraductal Carcinoma"[TI] OR DCIS[TI] OR "Ductal Carcinoma In Situ"[TI] OR "Noninfiltrating
Intraductal Carcinoma"[TI] OR "Atypical Ductal Hyperplasia"[TI]) AND (Radiotherapy[TI] OR
radiation[TI] OR irradiation[TI]) AND (Conserv*[TIAB] OR Spar*[TIAB] OR Preserv*[TIAB] OR
Segment*[TIAB]) AND (surgery[TI] OR surgical[TI] OR mastectom*[TI] OR resection*[TI] OR
operat*[TI]))) AND 2016/1:2021/3[DP] AND (JAPANESE[LA] OR ENGLISH[LA])((("Breast Neoplasms/radiotherapy"[Mesh] OR ("Breast Neoplasms/therapy"[Mesh] AND"Radiotherapy"[Mesh])) AND "Mastectomy, Segmental"[Mesh] AND ("Axilla"[Mesh] AND ("Lymph
術前化学療法後に病理学的完全奏功(pCR)が得ら
BQ3れた乳房部分切除術後患者でも、温存乳房への放射線療法は勧められるか？

Nodes"[Mesh] OR "Lymphatic Metastasis"[Mesh]))) OR ((Breast[TI] OR Mammary[TI]) AND(Tumo*[TI] OR Cancer*[TI] OR Carcinoma*[TI] OR Neoplasm*[TI]) AND (Radiotherapy[TI] OR
radiation[TI] OR irradiation[TI]) AND (Conserv*[TIAB] OR Spar*[TIAB] OR Preserv*[TIAB] OR
Segment*[TIAB]) AND (surgery[TI] OR surgical[TI] OR mastectom*[TI] OR resection*[TI] OR
operat*[TI]) AND lymph*[TIAB] AND node*[TIAB])) AND 2016/1:2021/3[DP] AND (JAPANESE[LA] OR
ENGLISH[LA])((("Breast Neoplasms/radiotherapy"[Mesh] OR ("Breast Neoplasms/therapy"[Mesh] AND

CQ1

全乳房照射において通常分割照射と同等の治療として寡分割照射は勧められるか？

"Radiotherapy"[Mesh])) AND "Dose Fractionation, Radiation"[Mesh]) OR ((Breast[TI] OR Mammary[TI])
AND (Tumo*[TI] OR Cancer*[TIAB] OR Carcinoma*[TI] OR Neoplasm*[TI]) AND (fractionat*[TI] OR
Hypofractionat*[TI]) AND (dose[TI] OR Radiotherapy[TI] OR radiation[TI] OR irradiation[TI]))) AND
2016/1:2021/3[DP] AND (JAPANESE[LA] OR ENGLISH[LA])((("Breast Neoplasms/radiotherapy"[Mesh] OR ("Breast Neoplasms"[Mesh] AND

乳房部分切除術後に断端が陰性の場合，全乳房
CQ2

照射後の腫瘍床に対するブースト照射は勧められるか？

"Radiotherapy"[Mesh])) AND "Mastectomy, Segmental"[Mesh] AND boost*[TIAB]) OR (((Breast[TIAB]OR Mammary[TIAB]) AND (Tumo*[TIAB] OR Cancer*[TIAB] OR Carcinoma*[TIAB] OR
Neoplasm*[TIAB]) AND (Radiotherap*[TIAB] OR Radiation therap*[TIAB])) AND (Segmental
Mastectom*[TIAB] OR conserv*[TIAB] OR preserv*[TIAB]) AND boost*[TIAB])) AND
2016/01[DP]:2021/03[DP] AND (JAPANESE[LA] OR ENGLISH[LA])(("Breast Neoplasms"[Mesh] AND "Mastectomy, Segmental"[Mesh] AND ("Accelerated Partial Breast
Irradiation"[TIAB] OR APBI[TIAB])) OR ((Breast Tumor*[TIAB] OR Breast Neoplasm*[TIAB] OR Breast

CQ3

乳房部分切除術後の照射法として加速乳房部分
照射(APBI)は勧められるか？

Cancer*[TIAB] OR Mammary Cancer*[TIAB] OR Breast Malignant Neoplasm*[TIAB] OR Breast
Malignant Tumor*[TIAB] OR Breast Carcinoma*[TIAB] OR Mammary Carcinoma*[TIAB] OR Mammary
Neoplasm*[TIAB]) AND (Segmental Mastectom*[TIAB] OR conserv*[TIAB] OR preserv*[TIAB]) AND("Accelerated Partial Breast Irradiation"[TIAB] OR APBI[TIAB]))) AND 2016/01[DP]:2021/03[DP] AND(JAPANESE[LA] OR ENGLISH[LA])((("Breast Neoplasms/radiotherapy"[Mesh] OR ("Breast Neoplasms/therapy"[Mesh] AND"Radiotherapy"[Mesh])) AND ("Lymphatic Metastasis"[Mesh] OR "Lymph Node Excision"[Mesh] OR
乳房部分切除術後に腋窩リンパ節転移4個以上のBQ4患者では領域リンパ節(鎖骨上)への放射線療法は勧められるか？

"Lymph Nodes"[Mesh] OR "Sentinel Lymph Node Biopsy"[Mesh]) AND "Mastectomy,
Segmental"[Mesh]) OR ((Breast[TW] OR Mammary[TI]) AND (Tumo*[TI] OR Cancer*[TI] OR
Carcinoma*[TI] OR Neoplasm*[TW]) AND (surgery[TI] OR surgical[TI] OR mastectom*[TI] OR
postmastectom*[TI] OR resection*[TI] OR operat*[TI]) AND (("positive lymph nodes"[TIAB] AND(Radiotherapy[TI] OR radiation[TI] OR irradiation[TI])) OR "regional nodal irradiation"[TIAB] OR
RNI[TIAB]))) AND 2016/1:2021/3[DP] AND (JAPANESE[LA] OR ENGLISH[LA])((("Breast Neoplasms/radiotherapy"[Mesh] OR ("Breast Neoplasms"[Mesh] AND"Radiotherapy"[Mesh])) AND ("Mastectomy, Segmental"[Mesh] OR (conserv*[TIAB] OR

乳房部分切除術および腋窩郭清後の腋窩リンパCQ4

節転移1～3個の患者では、領域リンパ節(鎖骨上)を照射野に含めることが勧められるか？

preserv*[TIAB])) AND (("lymphatic metastasis"[Mesh] OR "Lymph Nodes"[Mesh]) AND"Axilla"[Mesh])) OR (((Breast[TIAB] OR Mammary[TIAB]) AND (Tumo*[TIAB] OR Cancer*[TIAB] OR
Carcinoma*[TIAB] OR Neoplasm*[TIAB]) AND (radiotherap*[TIAB] OR "radiation therap*"[TIAB] OR
irradiation[TIAB])) AND (Segmental Mastectom*[TIAB] OR conserv*[TIAB] OR preserv*[TIAB]) AND(axilla*[TIAB] AND （lymph node*[TIAB] OR "lymphatic metastasis"[TIAB])))) AND
2016/03[DP]:2021/03[DP] AND (JAPANESE[LA] OR ENGLISH[LA])((("Breast Neoplasms/radiotherapy"[Mesh] OR ("Breast Neoplasms/therapy"[Mesh] AND

乳房部分切除術後に腋窩リンパ節転移4個以上のBQ5患者では、乳房全切除術後放射線療法(PMRT)が勧められるか？

("Radiotherapy"[Mesh] OR "Combined Modality Therapy"[Mesh]))) AND "Mastectomy"[Mesh] AND"Lymphatic Metastasis"[Mesh]) OR ((Breast[TIAB] OR Mammary[TIAB]) AND (Tumo*[TIAB] OR
Cancer*[TIAB] OR Carcinoma*[TIAB] OR Neoplasm*[TIAB]) AND (Radiotherapy[TI] OR radiation[TI] OR
irradiation[TI] OR PMRT[TI]) AND (mastectom*[TIAB] OR postmastectom*[TI]) AND (lymph*[TIAB] ORaxill*[TIAB]) AND metasta*[TIAB])) AND 2016/1:2021/3[DP] AND (JAPANESE[LA] OR ENGLISH[LA])((("Breast Neoplasms/radiotherapy"[Mesh] OR ("Breast Neoplasms/therapy"[Mesh] AND"Radiotherapy"[Mesh])) AND "Axilla"[Mesh] AND "Lymphatic Metastasis"[Mesh] AND"Radiotherapy,

CQ5

乳房全切除術後および腋窩郭清後の腋窩リンパAdjuvant"[Mesh]) OR ((Breast[TI] OR Mammary[TI]) AND (Tumo*[TI] OR Cancer*[TI] OR

節転移1～3個の患者では、乳房全切除術後放射Carcinoma*[TI] OR Neoplasm*[TI]) AND (Radiotherapy[TI] OR radiation[TI] OR irradiation[TI] OR

線療法(PMRT)が勧められるか？

PMRT[TIAB]) AND axilla*[TIAB] AND lymph*[TIAB] AND node*[TIAB] AND ("after surgery"[TIAB] OR
postoperative*[TIAB] OR adjuvant[TIAB]) AND metasta*[TIAB])) AND 2016/1:2021/3[DP] AND(JAPANESE[LA] OR ENGLISH[LA])((("Breast Neoplasms/radiotherapy"[Mesh] OR ("Breast Neoplasms/therapy"[Mesh] AND("Radiotherapy"[Mesh] OR "Combined Modality Therapy"[Mesh]))) AND "Mastectomy"[Mesh] AND
乳房全切除術後放射線療法(PMRT)では胸壁なら ("Thoracic Wall"[Mesh] OR CW[TIAB] OR "Sternoclavicular Joint"[Mesh] OR SC[TIAB])) OR
BQ6

びに鎖骨上リンパ節領域を照射野に含めるべき((Breast[TIAB] OR Mammary[TIAB]) AND (Tumo*[TIAB] OR Cancer*[TIAB] OR Carcinoma*[TIAB] ORか？

Neoplasm*[TIAB]) AND (Radiotherapy[TI] OR radiation[TI] OR irradiation[TI] OR PMRT[TI]) AND(mastectom*[TIAB] OR postmastectom*[TI]) AND (CW[TIAB] OR "chest wall"[TIAB] OR "thoracic
wall"[TIAB] OR SC[TIAB] OR Sternoclavicular[TIAB]))) AND (JAPANESE[LA] OR ENGLISH[LA])((("Breast Neoplasms/radiotherapy"[Mesh] OR ("Breast Neoplasms/therapy"[Mesh] AND("Radiotherapy"[Mesh] OR "Combined Modality Therapy"[Mesh]))) AND "Mastectomy"[Mesh] AND
リンパ節転移陰性で腫瘍径が大きい場合もしく
BQ7

は手術後断端陽性の場合は乳房全切除術後放射線療法(PMRT)が勧められるか？

(T3N0*[TIAB] OR pT3N0*[TIAB] OR pT3pN0*[TIAB] OR "T3-N0"[TIAB] OR T4N0*[TIAB] OR
pT4N0*[TIAB] OR pT4pN0*[TIAB] OR "T4-N0"[TIAB])) OR ((Breast[TIAB] OR Mammary[TIAB]) AND(Tumo*[TIAB] OR Cancer*[TIAB] OR Carcinoma*[TIAB] OR Neoplasm*[TIAB]) AND (Radiotherapy[TI]
OR radiation[TI] OR irradiation[TI] OR PMRT[TI]) AND (mastectom*[TIAB] OR postmastectom*[TI])
AND (T3N0*[TIAB] OR pT3N0*[TIAB] OR pT3pN0*[TIAB] OR "T3-N0"[TIAB] OR T4N0*[TIAB] OR
pT4N0*[TIAB] OR pT4pN0*[TIAB] OR "T4-N0"[TIAB]))) AND (JAPANESE[LA] OR ENGLISH[LA])((("Breast Neoplasms/surgery"[Majr] OR ("Breast Neoplasms/therapy"[Majr] AND"Mastectomy"[Mesh])) AND "Axilla"[Mesh] AND ("Lymph Node Excision"[Mesh] OR "Lymph

術前化学療法が奏功した場合でも乳房全切除術
FRQ1

後放射線療法(PMRT)は勧められるか？［検索依
頼：ALND omission］

Nodes/surgery"[Mesh] OR "Sentinel Lymph Node Biopsy"[Mesh]) AND "Lymphatic Metastasis"[Mesh])
OR ((Breast*[TI] OR Mammary[TI]) AND (Tumo*[TIAB] OR Cancer*[TIAB] OR Carcinoma*[TIAB] OR
Neoplasm*[TIAB]) AND (((surgery[TIAB] OR surgical[TIAB] OR dissection[TIAB]) AND (conserv*[TIAB]
OR segmental[TIAB]) AND axilla*[TIAB] AND "Lymph node"[TW] AND (metasta*[TIAB] OR
micrometasta*[TIAB] OR macrometasta*[TIAB])) OR ALND[TIAB]))) AND 2016/1:2021/3[DP] AND(JAPANESE[LA] OR ENGLISH[LA])

乳房全切除術後の再建乳房に対する放射線療法
BQ8

は勧められるか？

((("Breast Neoplasms/radiotherapy"[Mesh] OR ("Breast Neoplasms/therapy"[Mesh] AND"Radiotherapy"[Mesh])) AND "Mammaplasty"[Mesh] AND ("Autografts"[Mesh] OR "Transplantation,
BQ8a

自家組織による再建の場合、再建乳房に対するAutologous"[Mesh] OR "Breast Implants"[Mesh])) OR ((Breast[TI] OR Mammary[TI]) AND (Tumo*[TI]

放射線療法は勧められるか？

OR Cancer*[TIAB] OR Carcinoma*[TIAB] OR Neoplasm*[TIAB] OR oncology[TIAB]) AND(mammaplast*[TIAB] OR mammoplast*[TIAB] OR "breast reconstruction"[TIAB]) AND(Radiotherapy[TIAB] OR "radiation therapy"[TIAB] OR irradiation[TIAB]) AND (Autograft*[TIAB] OR
Autologous[TIAB] OR implant*[TIAB]))) AND 2016/1:2021/3[DP] AND (JAPANESE[LA] OR

BQ8b

人工物による再建の場合、再建乳房に対する放ENGLISH[LA])

射線療法は勧められるか？
((("Breast Neoplasms/radiotherapy"[Mesh] OR ("Breast Neoplasms/therapy"[Mesh] AND"Radiotherapy"[Mesh])) AND "Mammaplasty"[Mesh] AND ("Tissue Expansion Devices"[Mesh] OR

BQ8c

人工物による二期再建の場合、放射線療法はどのタイミングで行うべきか？

"Breast Implants"[Mesh])) OR ((Breast[TIAB] OR Mammary[TI]) AND (Tumo*[TIAB] OR Cancer*[TIAB]
OR Carcinoma*[TIAB] OR Neoplasm*[TW]) AND (mammaplast*[TIAB] OR mammoplast*[TIAB] OR
reconstruction[TIAB]) AND (Radiotherapy[TIAB] OR "radiation therapy"[TIAB] OR irradiation[TIAB])
AND ("Tissue Expansion Device"[TIAB] OR "Tissue Expansion Devices"[TW] OR implant*[TIAB]))) AND
2016/1:2021/3[DP] AND (JAPANESE[LA] OR ENGLISH[LA])((("Breast Neoplasms/radiotherapy"[Mesh] OR ("Breast Neoplasms/therapy"[Mesh] AND

乳房部分切除術後の領域リンパ節照射あるいは"Radiotherapy"[Mesh])) AND "Dose Fractionation, Radiation"[Mesh] AND ("Lymphatic

乳房全切除術後放射線療法(PMRT)を行う患者に Metastasis"[Mesh] OR "Lymphatic Irradiation"[Mesh] OR "Neoplasm Recurrence, Local"[Mesh])) OR
FRQ2

対して、通常分割照射と同等の治療として寡分((Breast*[TI] OR Mammary[TI]) AND (Tumo*[TIAB] OR Cancer*[TIAB] OR Carcinoma*[TIAB] OR

割照射は勧められるか？［検索依頼：

Neoplasm*[TW]) AND (Radiotherapy[TI] OR radiation[TI] OR irradiation[TI]) AND (HypoRNI[TIAB] OR

HypoRNI］

hypofractionat*[TIAB] OR HypoRT[TIAB] OR HypoARC[TIAB]))) AND (JAPANESE[LA] OR
ENGLISH[LA])((("Breast Neoplasms/radiotherapy"[Mesh] OR ("Breast Neoplasms/therapy"[Mesh] AND

CQ6

乳房手術後に腋窩リンパ節転移陽性で，領域リ"Radiotherapy"[Mesh])) AND "Lymphatic Metastasis"[Mesh] AND "Lymph Nodes/radiation

ンパ節照射あるいは乳房全切除術後放射線療法

effects"[Mesh]) OR ((Breast[TI] OR Mammary[TI]) AND (Tumo*[TI] OR Cancer*[TI] OR Carcinoma*[TI]（PMRT）を行う患者に対して，内胸リンパ節領 OR Neoplasm*[TI]) AND (Radiotherapy[TI] OR radiation[TI] OR irradiation[TI] OR PMRT[TIAB]) AND
域を含めることが勧められるか？

"internal mammary"[TIAB] AND lymph*[TIAB] AND node*[TIAB])) AND 2016/1:2021/3[DP] AND(JAPANESE[LA] OR ENGLISH[LA])((("Brain Neoplasms/radiotherapy"[Majr] OR ("Brain Neoplasms/therapy"[Majr] AND

FRQ3

センチネルリンパ節に転移を認めたが腋窩リン"Radiotherapy"[Mesh])) AND ("Neoplasm Metastasis"[Mesh] OR "secondary"[SH]) AND (WBI[TIAB] OR

パ節郭清が省略された患者に、領域リンパ節へ

whole[TIAB])) OR ((Breast*[TI] OR Mammary[TI]) AND (Tumo*[TIAB] OR Cancer*[TIAB] ORの放射線療法が勧められるか？［検索依頼：WBI Carcinoma*[TIAB] OR Neoplasm*[TIAB]) AND brain[TI] AND (WBI[TIAB] OR radiotherapy[TIAB] ORn≦10］radiation[TIAB] OR irradiation[TIAB] OR radiosurgery[TIAB]) AND metasta*[TIAB])) AND
2016/1:2021/3[DP] AND (JAPANESE[LA] OR ENGLISH[LA])((("Breast Neoplasms/radiotherapy"[Mesh] OR ("Breast Neoplasms/therapy"[Mesh] AND"Radiotherapy"[Mesh])) AND ("Mastectomy"[Mesh] OR "Breast Neoplasms/surgery"[Mesh]) AND

BQ9

乳房手術後放射線療法の適切なタイミングはどのようなものか？

"Time Factors"[Mesh]) OR ("Breast Cancer"[TI] AND (Radiotherapy[TI] OR radiation[TI] OR
irradiation[TI] OR PMRT[TI] OR (adjuvant*[TIAB] AND (therapy[TIAB] OR chemotherapy[TIAB] OR
trastuzumab[TIAB]))) AND (timing[TIAB] OR interval*[TIAB] OR delay[TIAB]) AND (surgery[TIAB] OR
postoperative*[TIAB] OR preoperative*[TIAB]))) AND 2016/1:2021/3[DP] AND (JAPANESE[LA] OR
ENGLISH[LA])((("Breast Neoplasms/radiotherapy"[Mesh] OR ("Breast Neoplasms/therapy"[Mesh] AND"Radiotherapy"[Mesh])) AND ("Breast Neoplasms/surgery"[Mesh] OR ("Breast
Neoplasms/therapy"[Mesh] AND ("Surgical Procedures, Operative"[Mesh] OR "Postoperative
Period"[Mesh] OR "Postoperative Care"[Mesh] OR "Postoperative Complications"[Mesh]))) AND

BQ10

BRCA病的バリアントを有する乳癌患者に対し、 ("Genes, BRCA1"[Mesh] OR "Genes, BRCA2"[Mesh] OR "BRCA1 Protein"[Mesh] OR "BRCA2
乳房手術後の放射線療法は勧められるか？

Protein"[Mesh])) OR ((Breast[TI] OR Mammary[TI]) AND (Tumo*[TI] OR Cancer*[TIAB] OR
Carcinoma*[TIAB] OR Neoplasm*[TIAB] OR oncology[TIAB]) AND (BRCA1[TIAB] OR BRCA2[TIAB])
AND (Radiotherapy[TIAB] OR "radiation therapy"[TIAB] OR irradiation[TIAB]) AND (surgery[TIAB] OR
surgical[TIAB] OR operati*[TIAB] OR postoperati*[TIAB]))) AND 1995/1:2021/3[DP] AND(JAPANESE[LA] OR ENGLISH[LA])((("Breast Neoplasms/radiotherapy"[Mesh] OR ("Breast Neoplasms/therapy"[Mesh] AND"Radiotherapy"[Mesh])) AND ("Neoplasm Recurrence, Local"[Mesh] OR "Lymphatic

FRQ4

乳癌の各所・領域リンパ節再発では、根治を目Metastasis"[Mesh]) AND "Thoracic Wall"[Mesh]) OR ((Breast*[TI] OR Mammary[TI]) AND

指した放射線療法が勧められるか？［検索依頼(Tumo*[TIAB] OR Cancer*[TIAB] OR Carcinoma*[TIAB] OR Neoplasm*[TIAB]) AND (radiotherapy[TIAB]

依頼：Locoregional Recurrence］

OR radiation[TIAB] OR irradiation[TIAB]) AND (recurren*[TI] OR metasta*[TI]) AND (Locoregional[TI]
OR local[TI] OR "Thoracic Wall"[TIAB]))) AND 2016/1:2021/3[DP] AND (JAPANESE[LA] OR
ENGLISH[LA])((("Bone Neoplasms/radiotherapy"[Majr] AND "Radiotherapy"[Mesh] AND "Bone
BQ11

有痛性乳癌骨転移に対して放射線療法は勧められるか？

Neoplasms/secondary"[Majr]) OR ((bone[TI] OR skeletal[TI] OR osseous[TI]) AND (Tumo*[TI] OR
Cancer*[TI] OR Carcinoma*[TI] OR Neoplasm*[TW]) AND (Radiotherapy[TI] OR radiation[TIAB] OR
irradiation[TI]) AND metasta*[TI] AND (treatment[TIAB] OR therapy[TIAB]))) AND 2016/1:2021/3[DP]AND (JAPANESE[LA] OR ENGLISH[LA])((("Bone Neoplasms/radiotherapy"[Mesh] OR ("Bone Neoplasms/therapy"[Mesh] AND

8 Gy/1回照射は有痛性乳癌骨転移の疼痛緩和をCQ7目的とした場合、分割照射と同等の治療として勧められるか？

"Radiotherapy"[Mesh])) AND "Bone Neoplasms/secondary"[Mesh] AND ("Pain"[Mesh] OR "Palliative
Care"[Mesh])) OR ((Bone[TI] OR skeletal[TI]) AND (Tumo*[TIAB] OR Cancer*[TIAB] OR
Carcinoma*[TIAB] OR Neoplasm*[TW]) AND (Radiotherapy[TI] OR radiation[TI] OR irradiation[TI] OR"8Gy"[TIAB]) AND (pain*[TIAB] OR palliative*[TIAB]) AND metasta*[TI])) AND 2016/1:2021/3[DP]AND (JAPANESE[LA] OR ENGLISH[LA])(("Brain Neoplasms/radiotherapy"[Majr] AND "Radiotherapy"[Mesh] AND "Brain

BQ12

乳癌脳転移に対して放射線療法は勧められるか？

Neoplasms/secondary"[Majr]) OR ((Breast[TI] OR Mammary[TI]) AND (brain[TI] OR cerebral[TI]) AND(Tumo*[TI] OR Cancer*[TI] OR Carcinoma*[TI] OR Neoplasm*[TI]) AND (Radiotherapy[TI] OR
radiation[TI] OR irradiation[TI] OR radiosurgery[TI]) AND metasta*[TI])) AND 2016/1:2021/3[DP] AND(JAPANESE[LA] OR ENGLISH[LA])3cm未満で1～4個までの乳癌脳転移に対して定CQ8

位手術的照射(SRS)を行った場合、全脳照射の追加は勧められるか？

(("Brain Neoplasms/therapy"[Mesh] AND "Radiosurgery"[Mesh] AND "Brain
Neoplasms/secondary"[Mesh] AND "Breast Neoplasms"[Mesh]) OR (Brain[TI] AND (Tumo*[TIAB] OR
Cancer*[TI] OR Carcinoma*[TI] OR Neoplasm*[TI]) AND (SRS[TI] OR radiosurgery[TI]) AND
metasta*[TI])) AND 2016/1:2021/3[DP] AND (JAPANESE[LA] OR ENGLISH[LA])((("Breast Neoplasms/radiotherapy"[Mesh] OR ("Breast Neoplasms/therapy"[Mesh] AND"Radiotherapy"[Mesh])) AND "Radiosurgery"[Mesh] AND ("Neoplasm Metastasis"[Mesh] OR

FRQ6

少数個転移・再発では、体幹部定位放射線治療"Neoplasm Recurrence, Local"[Mesh])) OR ((Breast*[TI] OR Mammary[TI]) AND (Tumo*[TIAB] ORが勧められるか？［検索依頼：OligoMeta］

Cancer*[TIAB] OR Carcinoma*[TIAB] OR Neoplasm*[TIAB]) AND (Radiotherapy[TI] OR radiation[TI] OR
irradiation[TI] OR radiosurgery[TI]) AND (oligometasta*[TIAB] OR oligorecurrence*[TIAB] OR
oligoprogression[TIAB]))) AND (JAPANESE[LA] OR ENGLISH[LA])