HERBICIDEFLAZASULFURON
Wide spectrum herbicide
Flazasulfuron is a sulfonylurea herbicide which was discoveredand developed by ISK in the late 1980’s.
It controls a wide range of weeds covering both annual andperennial species. It is a selective systematic herbicide forpre-emergence and early post-emergence weed control.
Flazasulfuron has been registered in various countries for use
in crops such as almonds and other tree nuts, citrus, conifers,grapes, sugarcane, warm season turfgrass, and in non-cropareas.

Physico-Chemical Properties

Toxicology & Ecotoxicology

Chemical structure

Rat LD50 (oral) : > 5,000 mg/kg (m/f)
Rat LD50 (dermal) : > 2,000 mg/kg (m/f)
Rat LC50 (inhalation) : > 5.99 mg/L (m/f)

OCH3
NN
SO2NHCONH
N
CF3

Skin irritation : non irritant (rabbit)
Eye irritation : slight irritant (rabbit)
Skin sensitization : not a sensitizer (guinea pig)

OCH3

Class : sulfonylurea
IUPAC name : 1-(4,6-dimethoxypyrimidin-2-yl)-3(3-trifluoromethyl-2-pyridylsulfonyl)urea
Molecular weight : 407.3
Molecular formula : C13H12F3N5O5S
Vapour pressure : < 0.013 mPa (25°C)
Water solubility : 2.1 g/L (25°C,pH7)
Form : white powder
Development code : SL-160

Application

Avian LD50 (acute oral) : > 2,000 mg/kg (quail, m/f)
Avian LD50 (acute oral) : > 2,250 mg/kg (mallard duck, m/f)
Fish LC50 : > 20 mg/L (trout, 96 h)
Bees LD50 (acute contact) : > 100 μg/beeDaphnia magna EC50 : > 20 mg/L (48 h)Mode of Action

Uses Flazasulfuron can be applied PREand POST to control broadleaf and grass
weed control, including sedge control.
Flazasulfuron can be applied in crops suchas almonds and other tree nuts, citrus, conifers,grapes, sugarcane, warm season turfgrass,and in non-crop areas.

Plant Uptake Flazasulfuron is rapidly absorbed by leaf and root tissue and is translocated, via
the phloem and xylem, to meristem tissue. Flazasulfuron controls weeds by inhibiting acetolactate synthase (ALS), also called acetohydroxy acid synthase (AHAS). ALS is a necessary enzyme
for the production of three branched-chain amino acids, isoleucine, leucine, and valine.
Symptoms Weeds treated with flazasulfuron will first begin to develop chlorosis in the newgrowth and then gradually, as the weed continues to be starved of the vital branched-chainamino acids, the chlorosis symptomology will develop in older growth. Chlorotic symptomology
then turns to necrosis and desiccation of the plant tissue occurs. Control typically takes 3-4weeks, from treatment to plant death.
Selectivity Crop selectivity of flazasulfuron exists based on the metabolic ability of some plants
to breakdown flazasulfuron into inactive metabolites.

ProductTrade Names

CHIKARA, KATANA, MISSION, PARANDOL, FLAMARK, 芝草原, 秀百宮, シバゲンDF, etc.

Formulations

25%WG, 10%WP

Registered Countries

Asia

Taiwan, South Korea, Japan, Thailand, ChinaEurope

Belgium, Bulgaria, France, Germany, Hungary, Italy, Romania, Serbia, Switzerland, etc.

AmericasUSA, Brazil, Colombia, etc.

ISHIHARA SANGYO KAISHA, LTD.

URL : http://www.iskweb.co.jp

E-mail : isk.bio@iskweb.co.jp

1-3-15 Edobori, Nishi-ku, Osaka 550-0002 TEL +81-6-6444-7154

FLAZASULFURONHERBICIDE

Wide spectrum herbicide

Visual Effect of Herbicidal Activity(Weed: Erigeron philadelphicus)

Characterisitics
ALS inhibitor
Excellent activity at low dosages(25–100 g a.i./ha)Broad weed spectrum including
grasses, broadleaf weeds andsedges
Safe to permanent crops such as
grapevine and citrus, sugarcane
and warm season turfgrass

At application

Safe to birds, fish, bees and otherbeneficial insects

7 days after application 20 days after application

Weed Spectrum
Weed Spectrum

SedgesBroadleaved weeds

Grass weeds

Scientific Name

Pre-emergence Application

Post-emergence Application

Rate (g a.i./ha)Rate (g a.i./ha)Common Name
2550100

2550100

Alopecurus geniculatus

Water foxtail

++

+++

+++

+++

+++

+++

Briza minor

Little quakinggrass

+++

+++

+++

++

+++

+++

Digitaria sanguinalis

Large crabgrass

++

+++

+++

++

+++

+++

Echinochloa crus-galli

Bamyard grass

++

+++

+++

++

+++

+++

Eleusine indica

Goosegrass

++

+++

+++

++

+++

+++

Lolium multiflorum

Italian ryegrass

++

+++

+++

+++

+++

+++

Poa annua

Annual bluegrass

+++

+++

+++

+++

+++

+++

Setaria viridis

Green foxtail

+

+++

+++

++

+++

+++

Amaranthus viridis

Slender amaranth++++++

+++

+++

+++

+++

Capsella bursa-pastoris

Shepherd’s-purse

++

+++

+++

+++

+++

+++

Cerastium glomeratum

Sticky chickweed

+++

+++

+++

+++

+++

+++

Chenopodium album

Common lamb's quarters

+++

+++

+++

+++

+++

+++

Conyza canadensis

Horseweed

++

+++

+++

++

+++

+++

Conyza sumatrensis

Fleabane

++

+++

+++

++

+++

+++

Hydrocotyle sibthorpioides

Lawn pennywort

++

++

++

++

+++

+++

Plantago asiatica

Chinese plantain+

+

++

++

++

+++

Polygonum lapathifolium

Pale smartweed

+++

+++

+++

++

++

+++

Rorippa palustris

Marsh yellowcress++++++++++++++++++

Cyperus microiria

Asian flatsedge++++++++++++++++++

Cyperus brevifolius

Mullumbimby couch++

+++

+++

+++

+++

+++

Cyperus rotundus

Purple nutsedge

+++

+++

++

+++

+++

+++: Excellent control,++: Good to Fair control,+: Poor control

Application: Pre-emergence or post-emergence (3–4 leaf-stage or less than 10 cm) of weeds
Adjuvant: non-ionic surfactant

ISHIHARA SANGYO KAISHA, LTD.

URL : http://www.iskweb.co.jp

E-mail : isk.bio@iskweb.co.jp

1-3-15 Edobori, Nishi-ku, Osaka 550-0002 TEL +81-6-6444-7154