SAFETY DATA SHEETSDS No.5010-29015

Revised date

April 15, 2019

1/5 page

1. PRODUCT AND COMPANY IDENTIFICATIONPRODUCT NAME
： 2% Potassium hydroxide Silicagel
NAME OF SUPPLIER： GL Sciences Inc.
ADDRESS： 22-1 Nishishinjuku 6-chome Shinjuku-ku Tokyo 163-1130, JapanCHARGE SECTION： International Sales Section
TELEPHONE No.
： +81-3-5323-6620
FACSIMILE No.
： +81-3-5323-6621
PRODUCT No.
： 5010-29015, 5010SDS No.
： 5010-29015
Research use only.
2. HAZARDS IDENTIFICATIONGHS CLASSIFICATIONHAZARDS SYMBOL： Skin corrosion/irritation： Category 2
Eye damage/irritation： Category 2ASpecific target organ toxicity (Single exposure)： Category 2<respiratory system>
Specific target organ toxicity (Repeated exposure)： Category 2<respiratory system>：

SIGNAL WORD
： Warning
HAZARD STATEMENTS：
H315
Cause skin irritation
H319
Cause serious eye irritation
H371
May cause damage to organs
H373
May cause damage to organs through prolonged or repeated exposure
PRECAUTIONARY STATEMENTS ：P260
Do not breathing dust/fume/gas/mist/vapours/spray.
P264
Wash hands thoroughly after handling.
P270Do not eat, drink or smoke when using this product.
P280
Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352
IF ON SKIN: Wash with plenty of water.
P305+P351+P338
IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
P308+P311
IF exposed or concerned: Call a POISON CENTER or doctor.
P314
Get medical attention if you feel unwell.
P332+P313
If skin irritation occurs: Get medical attention.
P337+P313
If eye irritation persists: Get medical attention.
P362+P364
Take off contaminated clothing and wash it before reuse.
P405
Store locked up.
P501
Dispose of contents/container in accordance with all applicable regulations.
3. COMPOSITION/INFORMATION ON INGREDIENTSCHEMICAL IDENTITY： Mixture
CHEMICALCHEMICAL NAMECONTENTFORMULACAS RNTSCA
INVENTRY

EINECS No.

Potassium hydroxide2%KOH1310-58-3

Listed215-181-3

Silicagel98 %SiO 2112926-00-8

Listed-PRODUCT NAME ： 2% Potassium hydroxide Silicagel
SDS No.5010-29015

Revised date

4. FIRST AID MEASURESGENERAL ADVICE

April 15, 2019

2/5 page： Wash off immediately with soap and plenty of water. In the case of respirable
dust, use self-contained breathing apparatus and dust impervious protectivesuit. Use personal protective equipment.
： Move victim to fresh air. If breathing is difficult, give oxygen. If irritation
persists, consult a physician.
： Remove contaminated clothes and shoes, rinse skin with plenty of water orshower. Use soap to help assure removal. If irritation persists, consult aphysician.
： Remove any contact lenses at once. Flush eyes well with flooding large
amounts of running water for at least 15 minutes. Assure adequate flushing byseparating the eyelids with sterile fingers. If irritation persists, consult aphysician. Never rub your eyes.
： Rinse mouth, give plenty of water to dilute the substance. Do not induce
vomiting. Never give anything by mouth to an unconscious person. Consult aphysician.

INHALATIONSKIN CONTACTEYE CONTACTINGESTION

5. FIRE FIGHTING MEASURES
EXTINGUISHING MEDIA： Powder, foam (alcohol foam), carbon dioxide, water spray.
FIRE & EXPLOSION HAZARDS： Toxic and irritating dust, fumes or smoke may be emitted.
SPECIAL PROTECTIVE EQUIPMENT FOR FIRE FIGHTERS： Fireman should wear normal protective equipment (full bunker gear) andpositive-pressure self-contained breathing apparatus.
6. ACCIDENTAL RELEASE MEASURESPERSONAL PRECAUTIONS： Remove ignition sources and ventilate the area. In case of insufficientventilation, wear suitable respiratory equipment. Avoid raising dust and avoid
contact with skin and eyes.
ENVIRONMENTAL PRECAUTIONS： Prevent spills from entering sewers, watercourses or low areas.
Comply with local disposal regulations.
METHODS FOR CLEANING UP： Do not touch spilled material without suitable protection. After material iscompletely picked up, wash the spill site with soap and water and ventilate thearea. Pull all wastes in a plastic bag for disposal and seal it tightly. Remove,clean, or dispose contaminated clothing.
7. HANDLING AND STORAGE
HANDLING： In case of insufficient ventilation, wear suitable respiratory equipment.
Avoid contact with eyes, skin, and clothing. Avoid prolonged or repeatedexposure. Handle this product with suitable protection.
After using this product, dispose of contents/container in accordance with allapplicable regulations and appropriate ways.
： Store away from sunlight, heat and all ignition sources in well-ventilated dryplace. Keep container tightly closed.
： Strong oxidizers, acids, reductants.

STORAGEINCOMPATIBLE PRODUCTS

8. EXPOSURE CONTROL/PERSONAL PROTECTION
ENGINEERING MEASURES： Use exhaust ventilation to keep airborne concentrations below exposure limits.
Use adequate ventilation.
VENTILATION： Local Exhaust ; Necessary, Mechanical(General) ; Recommended
CONTROL PARAMETERSCHEMICAL NAMEPotassium hydroxide
Silica gel

ACGIH
STEL 2 mg/m
Inhalable dust TWA=10mg/m3 ,Respirable dust TWA=3mg/m3(as PNOS)PERSONAL PROTECTIONRESPIRATORY PROTECTION

HAND PROTECTION
EYE PROTECTION
SKIN PROTECTION

3

OSHA PELNIOSH REL

None
TWA 20mppcf(80mg/m3 /%SiO2 )(as amorphous silica)

C 2 mg/m3
TWA 6mg/m3(as amorphous silica)： Half or full face piece respirator, self-contained breathing apparatus, supplied
air respirator, etc. Use respirators approved under appropriate government
standards and follow all regulations.
： Safety gloves： Safety glasses(goggles)： Protective clothing

PRODUCT NAME ： 2% Potassium hydroxide Silicagel
SDS No.5010-29015

Revised dateApril 15, 2019

3/5 page

9. PHYSICAL AND CHEMICAL PROPERTIESAPPEARANCE： WhitePHYSICAL STATE： Solid(Powder)
ODOR： No data available
pH： Strong basicity (in water)
BOILING POINT： No data available
MELTING POINT： No data available
FLASH POINT： No data available
FLAMMABILITY： No data available
AUTOIGNITION TEMPERATURE ： No data available
VAPOR PRESSURE： No data available
SPECIFIC GRAVITY (DENSITY) ： No data available
SOLUBILITY INWater： Insoluble
Organic solvent： Insoluble
PARTITION COEFFICIENT ;n-octanol/water： No data available
DECOMPOSITION TEMPERATURE： No data available
10. STABILITY AND REACTIVITY
REACTIVITY： Hygroscopic. Potassium hydroxide tends to absorb carbon dioxide in air.
CHEMICAL STABILITY： No data available
CONDITION TO AVOID： Sunlight, heat, moisture, contact with incompatible materials.
INCOMPATIBILE MATERIALS： Acidic materials, oxidants, reductants, alkaline compounds
HAZARDOUS DECOMPOSITION PRODUCTS： No data available
11. TOXICOLOGICAL INFORMATIONACUTE TOXICITY -oral： This product is not classified.
(Potassium hydroxide)： Rat LD50=273 mg/kg(SIDS,2004)
ACUTE TOXICITY -dermal： The classification is not possible in this product.
ACUTE TOXICITY -inhalation： The classification is not possible in this product.
SKIN CORROSION/IRRITATION ： This product is classified in Category 2.
(Potassium hydroxide)： The solid substance is described as being corrosive. In human skin exposure
cases, there were cases in which a third degree injury was caused and cases
in which corrosion of tissue with small perforations was observed due tobattery electrolyte (containing 25% of this substance) (SIDS(2004)). There is adescription (SIDS(2004), ECETOC TR66(1995)) that the skin is corrosive in
multiple skin irritation tests using rabbits. In addition, the pH of the aqueous
solution of this substance is about 13, and it is described that it exhibits strong
alkalinity (Suggested Reasoning Statement for Sanitary Society Acceptable
Concentration(1978), PATTY(6th,2012)). The substance is classified as Skin
Corr. 1A, H314 in the EU CLP classification (ECHA CL Inventory(Access onAugust 2017)). This substance is listed as "a single chemical substance andcompound designated by the Minister of Health, Labor and Welfare in theLabor Standards Act Enforcement Regulations Annex 1 to 4 No. 1 anddiseases determined by the Minister of Health, Labor and Welfare" aschemical substances causing skin disorders.
EYE DAMAGE/EYE IRRITATION ： This product is classified in Category 2A.
(Potassium hydroxide)： Skin corrosion / irritation is classified in Category 1. The substance isdescribed as corrosive to the eye at a concentration of 2.0% or more, and it isdescribed as strongly corrosive in eye irritation tests using rabbits (SIDS(2004)). In addition, the pH of the aqueous solution of this substance is about
13, and it is described that it exhibits strong alkalinity (Proposal Reason
Statement for Sanitary Society Acceptable Concentration (1978), PATTY (6th,2012)). In addition, this is described as a substance which causes the anterior
eye disorder according to “a single chemical substance and compounddesignated by the Minister of Health, Labor and Welfare designated by theMinister of Health, Labor and Welfare under Labor Regulation ActEnforcement Regulations Annex 1 of 4 No. 1 and diseases determined by theMinister of Health, Labor and Welfare”.

PRODUCT NAME ： 2% Potassium hydroxide Silicagel
SDS No.5010-29015

Revised dateApril 15, 2019

4/5 page： Mild conjunctival redness in eye irritation tests(OECD TG 404, Precipitatedsilica(Sident9)) using rabbits (SIDS (2006)、ECETOC JACC (2006)).
Slight or no irritation in eye irritation tests(Precipitated silica) using rabbits(SIDS (2006)).
SKIN SENSITIZATION： The classification is not possible in this product.
GERM CELL MUTAGENICITY： The classification is not possible in this product.
CARCINOGENICITY： The classification is not possible in this product.
REPRODUCTIVE TOXICITY： The classification is not possible in this product.
SPECIFIC TARGET ORGAN TOXICITY - single exposure ： This product is classified in Category 3.
(Potassium hydroxide)： The substance has been described as acting as a strong alkali on the skin and mucous membranes, and inhalation exposure to dust or mist may cause irritation and tissue damage in the upper respiratory tract, possi
bly resulting in septal injury and pulmonary edema (ACGIH (7th, 2001),SIDS (2004), PATTY (6th, 2012), Proposed reason book for Sanitary Soc
iety allowable concentration (1978)).
(Silica gel)
： Irritating to respiratory tract (SIDS (2006), ECETOC JACC (2006))
SPECIFIC TARGET ORGAN TOXICITY - repeated exposure ： This product is classified in Category 1.
(Potassium hydroxide)： For humans, it is noted that the injury caused by inhalation of dust and mist of thissubstance is mainly inflammation of the upper respiratory tract, and chronic action
causes ulcers in the nasal septum. However, there are no reports of surveys andresearches on airborne concentrations and the occurrence of disorders (Proposal
Reasons for Sanitation Society Allowed Concentrations(1978)). Exposure to dust ormist may cause irritation of the eyes and respiratory tract, lesions of the nasal
septum (ACGIH(7th, 2001)). As mentioned above, although there is not enoughinformation, it is obvious that this substance is an alkaline substance and causes
respiratory inflammation by inhalation.
ASPIRATION HAZARD： The classification is not possible in this product.
(Potassium hydroxide)： This is a fatal case of ingestion of this substance unintentionally or for thepurpose of suicide, and some of the causes of death include aspiration fromthe esophagus to the trachea, pneumonia etc. (ACGIH (7th, 2001)) and there
is a report that alkaline aspiration into the respiratory tract causes fatal injuries
to the larynx, trachea, bronchi, and lungs (SIDS (2004)).
(Silica gel)

12. ECOLOGICAL INFORMATION
Hazardous to the aquatic environment： This product is classified in Category 1.
(Potassium hydroxide)： Crustacean(Daphnia magna) 24hr-EC50>10,000 mg/L
Fish(Zebra fish) 96hr-LC50=10,000 mg/L(SIDS,2006)
BIODEGRADABILITY： No data available
BIOACCUMULATIVE POTENTIAL ： No data available
MOBILITY IN SOIL
： No data available
HAZARDOUS TO THE OZONE LAYER： Not listed in Montreal Protocol list.
13. DISPOSAL INFORMATION
Dispose in a hazardous-waste site in accordance with all applicable regulations. Any disposal practice must be incompliance with country, local, state, and federal laws and regulations (contact country, local or state environment
agency for specific rules).
14. TRANSPORT INFORMATIONIATAUN NUMBER： 3262UN PROPER SHIPPING NAME ： CORROSIVE SOLID, BASIC, INORGANIC, N.O.S. (2% Potassium hydroxide Silicagel)
CLASS： 8, Corrosives
PACKING GROUP： III
ADR/RID： 3262, Corrosives
DOT： 3262, Corrosives
MARINE POLLUTANT： Not classified

PRODUCT NAME ： 2% Potassium hydroxide Silicagel
SDS No.5010-29015

Revised date

April 15, 2019

5/5 page

15. REGULATORY INFORMATIONFor classification and labeling of chemicals in accordance with the applicable rules and regulations in the EU or eachcountry, refer to GHS classification of this product (See Section 2).
US REGULATION
EU REGULATION： OSHA HCS 2012/29 CFR 1910.1200： CLP Regulation ((EC) No. 1272/2008)

16. OTHER INFORMATIONNOTICE:The information contained in the SDS description is applicable exclusively to the chemical substance identified
herein and for its intended use as an analytical reference standard or reagent and to the unit quantity intended forthat purpose. The information does not relate to, and may not be appropriate for, any application or larger quantityof the substance described. Our products are intended for the use by individuals possessing sufficient technicalskill and qualification on use the material potential hazardous chemical. Accordingly, no representation or warranty,
express or implied, with respect to merchantability and fitness for a particular purpose is made with respect to theinformation contained herein.
Attention:
This product in terms of chemical identity and the unit amount provide is intended for use in chemical analysis andnot for human consumption, nor any other purpose.