Pulsar™

NMR

Delivering NMR to your benchtop

Pulsar TM
NMR for your laboratory

The PulsarTM NMR spectrometer from Oxford Instruments delivers affordable,high performance NMR spectroscopy into the laboratory environment.
NMR where you want it
Pulsar is a benchtop NMR spectrometer that offers
high resolution performance without the need for liquid
nitrogen, liquid helium or compressed gases. It uses a
standard mains electricity supply, and has no special
health and safety requirements. This means you can run
NMR spectra in your own lab, close to your own process,without having to send samples away to a remote NMR
facility and wait for the results. Of course, measurements
by high-field NMR may still be needed from time to time,
but Pulsar’s outstanding performance means a highproportion of measurements can be done instantly, on
the spot – when you need them.

Pulsar in the laboratory environment

Easy operation
Pulsar uses standard 5mm NMR tubes, and has
a highly efficient automated shimming routinethat optimises the shim in just a few minutes
when needed.
For simple 1D spectra, Pulsar has SoftLock– an advanced software lock that guarantees
absolute spectral stability without the need for
deuterated solvents. SoftLock is so effectivethat 2000 scans can be overlaid with nodetectable line broadening from misalignment.
Pulsar offers a traditional deuterium lock forSingle scan superimposed over 64 scans using SoftLock

2 Pulsarrunning 2D experiments.

PULSAR
Superior Performance
Pulsar gives you class-leading performance, obtained using a 1.4T (60MHz proton resonance) rare-earth
permanent magnet with superior homogeneity. The traditional design of the Pulsar magnet means that wellknown and understood shimming techniques can be used to achieve the best resolution available on any benchtop
NMR instrument.

Additional Experiments
In addition to routine 1H spectra, every Pulsar
for monitoring changes in specific functional groups
can also acquire 19F spectra using the same probe.
during the reaction. Visual comparison of the spectra
19An example F spectrum of 5-bromo-1,2,3at different stages of the reaction is straightforward.
trifluorobenzene is shown below. Pulsar is also ideal An example shown below is the transesterification of
for arrayed experiments. Sequential acquisition ofa triglyceride.
data during a chemical reaction provides a method

19F spectrum of 5-bromo-1,2,3 trifluorobenzene

Overlaid spectra of starting material and final productPulsar 3

Using Pulsar

Routine Experiments
NMR spectroscopy is an invaluable analytical techniquefor chemical analysis. The information from an NMR
spectrum complements the information obtained fromother types of instrumentation. In many cases it offers
unique information about the sample material.

generated by hydrogen atoms in an ethyl (CH3CH2-) groupin the molecule.
Integration of the peaks provides a method for determining
the number of hydrogen atoms present in each chemicalgroup. The distance between the peaks in these multipletsallows measurement of the coupling constants.

NMR is an excellent technique for the identification ofmaterials and chemical groups. These example spectra(below) show materials with the same molecular formula,
C6H10O2, yet which are chemically different. The NMR
spectra differ significantly even in the case of trans-2- andtrans-3-hexenoic acids (a pair of structural isomers
which consist of the same functional groups and chainlengths).
The spectral data obtained on Pulsar shows clearseparation of the multiplets commonly observed in NMRspectra. The example below shows the typical multiplets

1D 1H spectrum of ethyl crotonate

4 PulsarSpectra of different structural isomers of C6H10O2

PULSAR
Carbon-13

Overnight

C measurements are a common requirement in organic
chemistry laboratories, and Pulsar offers outstanding

13

C performance. The excellent sensitivity, resolution
and lineshape of Pulsar mean that measurement of13
C compounds with sample concentrations down to0.5 M is practical in less than 2 hours. Neat samples cangive good results literally in minutes. Even with weakersamples the excellent stability of the Pulsar shims
and frequency lock mean that high quality data can becollected in an overnight run.
13In addition to 1D proton decoupled carbon, polarisationtransfer experiments such as DEPT are available
providing additional information about the number ofhydrogen atoms attached to each carbon. The datafrom DEPT-45, DEPT-90 and DEPT-135 experiments canbe combined in linear combination to produce edited
spectra containing signals from only CH, CH2 and CH3
groups respectively.
2D 1H – 13C correlation experiments are also available.
C{1H}
ArC-H
-C=O
ArC
13-CH2-Four Hours

Two Hours

One Hour1D 13C spectra of 0.5 M ibuprofen

CHCH2CH3C{1H}

13-CH3

DEPT-45

DEPT experiments linearly combined

DEPT-90

DEPT-135

DEPT dataset from diethyl phthalate. Total time for acquisition four minutes

Pulsar 5

2D Homonuclear NMR

Pulsar’s exceptional stability and high performanceelectronics allow a wide range of 2D homonuclear
experiments to be carried out. These include:
COSY – classic 2D correlation spectroscopy providing
information about mutually coupled nuclei andneighbouring atoms.
J-resolved – decoupling the chemical shift informationfrom the J-coupling which helps separate overlapping
multiplets.
TOCSY – exploits the connectivity through theJ-couplings of an unbroken chain of coupled nuclei
to provide information on the backbone structure oforganic molecules.
Pulsar is also able to offer selective 1D TOCSY, whichallows the user to quickly identify all the peaks coupledin an unbroken chain to the chosen peak.

J-resolved spectroscopy of the aromatic region of 2-(2-hydroxyphenyl) benzothiazole

6 Pulsar

Correlation Spectroscopy (COSY) data for ethyl crotonate

Total Correlation Spectroscopy (TOCSY) data of 2-hexenoic acid

PULSARClass leading
performance

Innovative, Intuitive,
Intelligent Software
Pulsar software is a combination of Oxford Instruments’
own SpinFlow graphical user interface, and Mestrelab’s
powerful Mnova software.
SpinFlow enables the user to quickly and easily create
routine experiments for spectra collection or relaxation
measurements, using an intuitive, seamless workflow
package. Automated setup routines ensure that theinstrument can be optimised for peak performance by
all users regardless of their level of expertise. Running asample can be as simple as selecting the experiment andclicking the “Acquire” button. SpinFlow also caters forexperienced users who may wish to alter the experimental
parameters, or even write their own pulse sequences.

Once data collection is complete, the data is
automatically transferred into Mnova, which has
a full suite of advanced routines for processing
and analysing NMR data. It also has a rangeof spectral display options including 2D and3D stacking, which are particularly useful forreaction monitoring experiments.

Workflow approach enhancing productivity

Stack display allows analysis of time course experiments

Pulsar 7

PULSAR
Providing a wide range of service giving total peace of mind

MQC

Oxford Instruments
Worldwide Support and Service
We take great pride in working in close partnership with ourcustomers. Our goal is to provide comprehensive technicalsupport throughout the product’s life.
When choosing to work with Oxford Instruments you are safein the knowledge that you have the backup and support of ourskilled product champions and dedicated support engineers
throughout the complete lifetime of your instrument. We offer
a range of support packages that provide you with the levelof service you require.
Our goal is to provide our customers

Also available from
Industrial Analysis:

with faultless service and swift expert
maintenance on our products
to ensure they perform toMQC benchtop NMR analysers for fast

their highest capabilities.

and easy measurement of fat,oil and moisture.

visit www.oxford-instruments.com/pulsar for more information or email: industrial@oxinst.com

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