March 21, 2024
LIFENET INSURANCE COMPANY
Eisai Co., Ltd.

Lifenet and Eisai Co-Develop Dementia Insurance “be”
Supporting early detection and treatment of dementia andmild cognitive impairment (MCI)
LIFENET INSURANCE COMPANY (Headquarters: Chiyoda Tokyo, President: Ryosuke Mori, “Lifenet”) andEisai Co., Ltd. (Headquarters: Bunkyo Tokyo, CEO: Haruo Naito, “Eisai”) announced today that they haveco-developed Dementia Insurance “be”, a dementia insurance that supports early detection and treatment ofdementia and mild cognitive impairment (hereafter, “MCI”) as one of the initiatives under the capital andbusiness alliance agreement concluded in August 2022 for collaboration in dementia and other areas.
■ Environment Surrounding Dementia
Prevalence of dementia is increasing year-by-year amid an aging population, among other factors. In
Japan, it is estimated that approximately one in five people aged 65 or older will be living with dementia by
2025*1, and it is a common disease that could affect anyone. In addition to medical and nursing care costs,
dementia can also cause financial burden to family members who are responsible for nursing and otherforms of care, such as transportation costs due to long distance commutes required for care and reduced
income due to decreased work hours.
■ Background Behind the Development of “be”
In August 2022, Lifenet and Eisai entered into a capital and business alliance agreement to collaborate
in dementia and other areas with the aim of helping reduce the burden of medical and nursing care forpeople living in Japan’s aging society, and have been considering new insurance products and services
as a joint initiative.
For the early treatment of dementia, it is thought that detecting the disease in the stage of MCI isimportant. MCI is the stage just before dementia diagnosis, where cognitive function is somewhere
between the healthy and dementia states. Early detection and appropriate preventative measures may
prolong or restore the existing state, or reduce the progression to dementia.
Although some measures including lifestyle changes and exercise are considered effective in treating
MCI, with the approval of a new pharmaceutical treatment for some types of MCI and mild dementia in
2023*2, medication may also become an option for early treatment. Pharmaceutical treatment is coveredby public service, but it is important to be financial prepared as a certain amount of co-payment is required,including for tests and other expenses.
In light of these circumstances, Lifenet and Eisai co-developed a dementia insurance based on theconcept of early detection and treatment, by leveraging Eisai’s experience and network in drug discovery
and disease awareness activities in the field of dementia, which it has built up over many years, andLifenet's know-how and technologies cultivated in insurance products and related services. This dementia
insurance product is offered by Lifenet.
■ Overview of Dementia Insurance “be”
Dementia Insurance “be” supports the early detection and treatment of dementia, increasing treatment
options by providing generous coverage from the MCI stage.
In addition, in order to detect dementia at an early stage, it is important for not only policyholders but
also their family members and others around them to pay attention to their brain health and understandthe differences between age-related forgetfulness and cognitive decline leading to dementia. At the sametime as the launch of Dementia Insurance “be”, an official LINE account Brenavi*3 focused on Eisai’s
dementia-related content will be provided to support the prevention, early detection, and aftercare ofdementia through the provision of information on brain health, a search function for medical institutions,brain training games and brain-stimulating exercise content.
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■ Coverage of Dementia Insurance “be”
Lump-sum benefit for
dementia diagnosis
Lump-sum benefit for
MCI diagnosis

Coverage・ Lump-sum benefit for dementia diagnosis can be paid after first-time diagnosis ofdementia
・ Lump-sum benefit for MCI diagnosis can be paid after first-time diagnosis of MCI*Summary of coverage. Details of coverage will be available on Lifenet’s website after launch (Japanese Only).

■ Newly Launched Services to Support Maintenance and Improvement of Brain Health, andUnderstanding on MCI/Dementia
1. Exclusive Service for Policyholders of Dementia Insurance “be”
Eisai’s brain health (brain performance) self-check tool NouKNOW® (non-medical device) is planned to
be offered to Dementia Insurance “be” policyholders as an ancillary service by the end of 2024. NouKNOW
is a tool that uses a simple card test using a PC, tablet or smartphone device to perform four tests
evaluating psychomotor function, attention, learning and memory, and working memory. Its purpose is not
to prevent or diagnose disease, but to raise policyholders’ awareness of brain health through regularchecks.
2. Services Available for Everyone
Brenavi will be launched as a service to support the maintenance and improvement of brain health andunderstanding of MCI and dementia. Brenavi is an official LINE account that provides information related
to MCI and dementia. This service is not limited to Dementia Insurance “be” policyholders and is available
to everyone.
It will introduce a wide range of brain-related information, including free brain training game Brain
Workout*4, the exercise program Brepacise*4 that stimulates the brain while having fun, and Forgetfulness
Consultation Navi*4 where users are able to search for medical institutions throughout Japan where they
can have a consultation regarding forgetfulness.
*1 Source: Cabinet Office, "Annual Report on the Aging Society, Fiscal Year 2017 Edition”*2 New treatment is indicated for patients of MCI and mild dementia due to Alzheimer's disease*3 Brenavi is an official LINE Account operated by Lifenet*4 Services provided by Eisai* The Brenavi LINE account can be added as a friend by scanning the QR code on the right. (Japanese only)■ About Lifenet
URL: https://ir.lifenet-seimei.co.jp/en/
Remembering the original purpose of life insurance - mutual support - LIFENET INSURANCE COMPANY
was founded with the goal of offering simple, convenient and competitively priced products and services
based on the highest levels of business integrity. We sell these products and services directly to customersover the Internet. We aim to be the leading company driving the growth of the online life insurance market.
■ About Eisai
URL: https://www.eisai.com/
Eisai's Corporate Concept is "to give first thought to patients and people in the daily living domain, andto increase the benefits that health care provides." Under this Concept (also known as human health care(hhc) Concept), we aim to effectively achieve social good in the form of relieving anxiety over health andreducing health disparities. With a global network of R&D facilities, manufacturing sites and marketing
subsidiaries, we strive to create and deliver innovative products to target diseases with high unmet medical
needs, with a particular focus in our strategic areas of Neurology and Oncology.
In addition, we demonstrate our commitment to the elimination of neglected tropical diseases (NTDs),
which is a target (3.3) of the United Nations Sustainable Development Goals (SDGs), by working on various
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activities together with global partners.
For more information about Eisai, please connect with us on X, LinkedIn and Facebook.

Contact:
LIFENET INSURANCE COMPANY, Investor Relations/Corporate Planning Department
TEL：+81-3-5216-7900
Eisai Co., Ltd., Public Relations Department
TEL：+81-3-3817-5120
Disclaimer: This is a summarized translation/version of the original Japanese document, prepared andprovided solely for readers' convenience. In case of any discrepancy or dispute, the Japanese document
prevails.

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