Eco-friendly oxidizing reagent
The world's first industrial production !

Sodium HypoChlorite Pentahydrate(5)NaClO･5H2O

Technical Data

Notable features of SHC5®
(1) High concentration
 High volumetric efficiency leads to better productivity and waste waterreduction.

(2) High purity
 The oxidizing reagent containing minimal amounts of NaCl and NaOH.

(3) High stability
 Stable for 1 year below 7℃ in a sealing and lightproof container.

(4) Adjustable to highly concentrated
aqueous solution
 Easy to prepare any concentration of aqueous solution at room
temperature (approx. ≦30%).

(5) Applicable to organic synthesis
 Alcohol and sulfide can be oxidized selectively.
 Various oxidation reactions are possible for both homogeneous andheterogeneous systems.

AppearanceCrystals

Table of contents
1. Notable features of SHC5® ............................................................................................................... 1(1) High Concentration ......................................................................................................................... 1(2) High Purity ............................................................................................................................................ 1(3) High Stability ...................................................................................................................................... 2
2. Chemical and physical properties .................................................................................................. 3
3. Solubility ....................................................................................................................................................... 4
4. Oxidizability of SHC5® ......................................................................................................................... 5(1) Oxidation reactions of alcohols ............................................................................................... 6(2) Oxidation reactions of sulfur compounds ........................................................................... 7(3) Other oxidation reactions ............................................................................................................ 95. Safety assessment ............................................................................................................................... 10(1) BAM Friction test .......................................................................................................................... 10(2) Drop hammer test ......................................................................................................................... 106. Thermal behavior(DSC measurement) ........................................................................................ 11(1) Stability with metals .................................................................................................................... 11(2) Stability with resins ...................................................................................................................... 117. Precautions for handling, storage, disposal and transportation .................................. 12(1) Package ............................................................................................................................................. 12(2) Precautions for handling ........................................................................................................... 13(3) Precautions for storage and disposal ................................................................................ 13(4) Transport information ................................................................................................................. 138. Japanese regulatory information .................................................................................................. 14～What is sodium hypochlorite pentahydrate (SHC5®) ?～Although the existence of “sodium hypochlorite pentahydrate” has been known for a long time, only
aqueous solution of about 12% has been industrially available. Nippon Light Metal Company has
succeeded in producing sodium hypochlorite pentahydrate in industrial scale for the first time in
the world and launched a new product in 2013, under the name of "SHC5®" which is abbreviatedname of Sodium HypoChlorite Penta(5)hydrate. SHC5® has higher volumetric efficiency comparedwith conventional aqueous solution and it has been revealed that SHC5® shows a unique reactivity
in organic reactions.

Notable features of SHC5®
(1) High concentration
The available chlorine concentration of SHC5® is 42% (44% as NaClO), whilethat of conventional aqueous sodium hypochlorite solution is 12%.
SHC5® is about 3.5 times higher in concentration ratio.
Significant waste reduction is achievable.

< Comparison of conventional aq. NaClO solution with SHC5® under the same molar condition >SHC5®(Crystals)

Conventional aq. NaClO

Available chlorine＝12%
Available chlorine＝42%✔ Volume decreased to approx.1/3✔ Waste decreased to approx.1/5(2) High purity
SHC5® prepared by our patented manufacturing process is a high-purity
product with reduced NaOH, NaCl, NaClO3, NaBrO3 and metal impurities suchas iron and chromium.
※ Conventional aqueous NaClO solution is prepared by introducing chlorine gas(Cl2) into aqueoussodium hydroxide(NaOH) solution. It essentially contains sodium chloride(NaCl) produced
during manufacturing process and various impurities derived from raw materials.

[1](3) High stability
SHC5® is stable for 1 year below 7℃ in a tightly sealed plastic container
stored in the dark.
High available chlorine concentration is maintained for about 1 week at 20℃,
but decomposition accelerates and produces sodium chloride and sodiumchlorate(NaClO3)※ during prolonged storage. It decomposes markedly in themolten state(30℃).
※ Decomposition of SHC5® produces sodium chlorate(NaClO3) which violently reacts in contact
with organic materials, sulfur and metal powder. SHC5® should be kept away from them. Make
sure to seal tightly and store below 7℃ in the dark.

45
Available chlorine [%]4035-20℃

307℃

2520℃

2030℃

15100100200
Storage period [day]Stability of SHC5®

300

Available chlorine [%]45

40-20℃
7℃
20℃
30℃

35300510152025
Storage period [day]Stability of SHC5® (Enlarged figure of 30 days)

[2]

30

Chemical and physical properties
Chemical property

Specification

Chemicalcomponents
Available chlorine※[%](Typical value)

SHC5®
≧39.0(42.0)
Pale yellow
transparent
0.05
0.120.05
0.005

Aqueous solution

Composition

NaOH[%]
NaCl[%]NaClO3[%]NaBrO3[%]

Conventional
aq. NaClO soln.
≧12.0(12.8)
0.8
12.4
0.90.01※ The concentration of available chlorine can be calculated by converting the weight percent of sodium
hypochlorite into its equivalent as chlorine molecule shown in the following equation. One molecule of sodium
hypochlorite corresponds to one molecule of chlorine.

Available chlorine concentration
Molecular weight of chlorine 70.9
Molecular weight of sodium hypochlorite 74.4

! weight percent of NaClO

0.95 ! weight percent of NaClO

Physical property
SHC5®
Molecular formula
Molecular weight
Appearance
Density[g/cm3]
Untapped bulk density[g/cm3]
Solubility
Heat of dissolution[J/g]Melting point[℃]

NaClO･5H2O
164.52
Pale yellow crystals
0.8
Insoluble
in organic solvent※293(Endothermic)
25-27®

※ Alcohol is not suitable for solvent as it reacts with SHC5 .

[3]Conventional
aq. NaClO soln.
NaClO
74.44
Pale yellow liquid
1.1-1.2-Solubility
Insoluble in most organic solvents.(Alcoholic solvents may react with SHC5®
and corresponding oxidized compounds are formed.)
Any concentration of the solution(approx. ≦30%)can be prepared simply by
dissolving SHC5® with water.
20% NaClO solution prepared from SHC5® is stable even after 24 hours at20℃.

Target concentration(Available Chlorine)
[%]
0.1
1.0
5.0
10.0
13.0
15.0
20.0
25.0
30.0

SHC5®
[g]

Water
[g]

2.4
24.0
124.0
258.8
345.1
405.0
562.4
732.1
914.3

996.7
983.0918.0
828.2
769.9
729.0
618.6
497.9
365.7

[4]

Density(solution)[g/cm3]
1.00
1.01
1.04
1.09
1.12
1.13
1.18
1.23
1.28

Oxidizability of SHC5®
Most of other oxidizing reagents have toxic and explosive issues. However,
SHC5® does not have these kinds of risks and it is an eco-friendly oxidizing
reagent, producing only sodium chloride and water as by-products.
Owing to high available chlorine concentration (42%) of SHC5®, it allows
higher volumetric efficiency.
SHC5® can be applied to various reactions as shown below.

OO
R
R

O
R

HOH

OH
R
R

O O
S
R
Cl

R'S

R

SorR SH

R'OH

O O
S
R
BrR(+NaBr)

OO

R

X

X=Cl, Br, I

S

RR'O

HOR

OSO O
SR
R'

R
R+ NaX

OH

IN

R
R

AcO I OAc
TsN
R
R

[5]

O
H

TsOH
R'R'

O

H

R
O
R'

(1) Oxidation reactions of alcohols
The oxidation reactions of various alcohols proceed smoothly without pH
adjustment and corresponding ketones or aldehydes are obtained selectively.
(Patent number : JP 6176177)
Oxidations of primary alcohols to carboxylic acids are also possible with asimple modification of the reaction conditions.

i) Application of oxidation to aldehyde/ketone

Synlett 2014, 25, 596-598.
Tetrahedron 2016, 72, 2818-2827.
ii) Application of oxidation to carboxylic acid[6]

(2) Oxidation reactions of sulfur compounds
Selective oxidations of sulfides to sulfoxides or sulfones are realized by simple
selection of the solvent. (Patent publication number : JP 2017-52730)

RO
S

SHC5 (1 eq.)
R'CH3CN/H2ORSSHC5 (>2 eq.)
R'Toluene/H2OO OSRR'i) Application of oxidation to sulfoxide

Synlett 2015, 26, 2547-2552.
ii) Application of oxidation to sulfone

42nd Symposium on Progress in Organic Reactions and Syntheses 2016, 2P-53.(Japanese)[7]

The reaction of disulfide or thiol with SHC5® in acetic acid gives
corresponding sulfonyl chloride in a short time and in high yield. (Patentnumber : JP 6149667)

Chem. Lett. 2015, 44, 185-187.

In the presence of sodium bromide(NaBr), the reaction gives high yield of thecorresponding sulfonyl bromide. (Patent publication number : JP 201752728)

41st Symposium on Progress in Organic Reactions and Syntheses 2015, 2P-33.(Japanese)[8](3) Other oxidation reactions＜Synthesis of (Diacetoxyiodo)arenes＞(Diacetoxyiodo)arenes are easily and safely synthesized by SHC5®.

J. Org. Chem. 2018, 83, 14262–14268.

＜Cleavage of glycols＞

Trans-isomer which is usually resisted to this type of reaction can also beapplied for the oxidative cleavage by SHC5®.

J. Org. Chem. 2019, 84, 8330–8336.

[9]

Safety assessment
According to the testing methods of explosives based on the Japanese Industrial
Standards (JIS K 4810), the BAM friction test and the drop hammer test have been
applied to SHC5®. The results of both tests were negative. This means that SHC5®
is not an explosive compound under normal conditions.

(1) BAM friction test(JIS K 4810：2003 Testing methods of explosives)

Friction panel after the test

Result of BAM friction test
Condition(position)

ResultJIS grade

Limiting Load:353 N (VI)

Negative (0/6)

Grade 7(2) Drop hammer test(JIS K 4810：2003 Testing methods of explosives)

Sample after the test

Result of Drop hammer test
Condition

ResultJIS grade

Limiting impact energy: 24.5 J

Negative (0/6)

Grade 8National Institute of Advanced Industrial Science and Technology, measured in 2016[10]

Thermal behavior(DSC measurement)(1) Stability with metalsvessels cannot be used as reactors. On
the other hand, titanium did not reactwith SHC5®, thus the reaction of SHC5®

(NaOCl·5HO)(NaClO·5H22O)
555342 J/g
447
397
284

287 J/g31

can be performed in titanium vessels aswell as glass wares.

367 J/g

102291769Heat flow (W/g)

The sharp peak was observed at 100℃
in DSC measurement with SUS304H.
This result shows that stainless steel
reacts with SHC5®, thus stainless(NaOCl·5H2 O+SUS304H)
O+SUS304H)(NaClO·5H
2100532917423 J/g

93268 J/g

217 J/g
256

179

31
(NaOCl·5HO+Ti)(NaClO·5H22O+Ti)
29 56 110 321 J/g
186930274 J/g

0100

425334 J/g
437392271

200300Temperature (℃）

400

500

DSC chart with SUS304H and Ti(2) Stability with resins
low-density polyethylene (PE) andpolypropylene(PP)aroundroom
temperature. On the other hand,decomposition of resins was observedin the high temperature range. Theseshow that above resins are able to beused as containers only below 25℃.

5(NaOCl·5HO)(NaClO·5H2 O)2342 J/g
447397367 J/g
10255
291769284

31 287 J/g(NaOCl·5H2 O+LD-PE)
O+LD-PE)(NaClO·5H
2Heat flow (W/g)

No changes are observed in the resultsof the measurement with high- and297 J/g 133 J/g
58107
207
30
1772
165
26232376

1006 J/g

264 J/g(NaOCl·5H2 O+HD-PE)
O+HD-PE)(NaClO·5H
2396123 J/g
55 308 J/g
104 138 209291671 132 178
265
10 J/g264 J/g
311297 J/g(NaOCl·5HO+PP)(NaClO·5H22 O+PP)
54460 J/g
107
193

73

166
139 J/g

29183932631008 J/g

31 275 J/g
0100

200300Temperature (℃)

400

DSC chart with resins

[11]

500

Precautions for handling, storage,
disposal and transportation(1) Package
500 g
10 kg

: High-density polyethylene container: 0.1 mm thickness polyethylene bag, heat-sealed,delivered in double packing
Refrigerated transport by reefer truck or frozen delivery are required.

<500 g sample – Package appearance>

Inner package
Φ125×H130 mm

Outer package
W280×D210×H190 mm (Incl. upper lid)

<10 kg - Package appearance>- Bag size (PE)450×670 mm[12](2) Precautions for handlingContact with metal, cloth and paper causes heating and decomposition. Avoid
contacting SHC5® with weighing paper and metal spoon. Use glass or plastic
equipment.
Avoid exposure to heat and light. SHC5® melts above 25℃. Decomposition isaccelerated with heat, light or carbon dioxide in the air. Weighing should bequickly as possible.
The used equipment should be washed with a large amount of water, andwaste water needs to be treated with reducing reagent such as sodium sulfite
for disposal.
Avoid skin/eye contact and breathing in vapor, mists or aerosols. Wearprotective equipment and eye protection when using. Wash with plenty of waterand seek medical attention immediately in case of contact on skin or in eye.
Avoid contacting SHC5® with acid. Harmful chlorine gas will be generated.
For other hazards, please refer to the instructions for conventional aqueous
NaClO solution.

(3) Precautions for storage and disposal
Store below 7℃ in sealed container and keep away from light. Use up as
soon as possible after opening.
SHC5® is deliquescent material. The decomposition is accelerated by lightand carbon dioxide in the air. Keep tightly sealed to preclude contact withlight, moisture and air.
For disposal, dissolving with a large amount of water and treatment withreducing reagents such as sodium sulfite are required prior to discharge.

(4) Transport information
There is no regulation for domestic land transportation in Japan. All transports
need to be conducted according to above "precautions for handling" and"precautions for storage and disposal”.
For the transport by air or by sea, this product is classified as hazardous
materials which require a specific shipping arrangement based on UN number
3212. It is highly recommended to consult with freight forwarders about
details in advance and follow their instructions.

[13]

Japanese regulatory information
METI registration number:(1)-237

Industrial Safety and Health Act : Existing chemical substances
Enforcement Order of Industrial Safety and Health Act
Annex 1 Dangerous goods oxidizing substanceFire Service Act: Not applicable
Toxic Substances Control Law : Not applicable
HS code: 2828.90-000UN Number: UN3212 Class 5.1(Oxidizing substance)
Ship Safety Law
andProduct name: Inorganic hypochlorite: Notification of regulations for the carriage
storage of hazardous materials in ship

Aviation Law
Act on Port Regulations

Annex Article 1 Oxidizing substance: Enforcement regulation Article 194
Oxidizing substance: Enforcement regulation Article 12
Dangerous goods (Oxidizing substance)

Water Pollution Prevention Act: Specified substance(Article 2-4, Enforcement order Article 3-3)
Marine Pollution Prevention Law : Not applicable
Law for Promotion of Chemical Management(PRTR Law)
: Not applicableRefrigeration or cold storage is required for this product. Avoid contact to skin or clothing. Make sure properties, handling
methods and others in Safety Data Sheet (SDS) before use. The data shown in this catalog are typical values, not theguaranteed values. Suitability should be ascertained when using this product for application not described in this catalog.

[14]http://www.nikkeikin.com/
Headquarters

Urbannet Uchisaiwaicho Building.,
1-1-13, Shimbashi, Minato-ku, Tokyo 105-8681 Japan
Market Development Department, Chemicals Division
TEL : +81-3-6810-7109
2020.08