Cytokine and Chemokines
Antibodies for neutralizing anddetecting cytokines and their receptors
bioxcell.com

Cytokine and Chemokine Antibodies
α-mouse IL-4 (BP0045)

α-mouse IL-2 p40 (BP0051)

α-mouse IFNγ (BP0055)

α-mouse TNFα (BP0058)

IL-12 p40
(50 kDa)

IFNγ (21 kDa)
TNFα (17 kDa)

IL-4 (13 kDa)
Purified IL-4

Purified IL-12 p40

Purified IFNγ

Purified TNFαInVivoMab InVivoPlus
CatalogCatalog

Antigen

Reactivity

Application

Clone

IL-1α

mousein vivo IL-1α neutralization

ALF-161

IL-1ß

mouse/rat

in vivo and in vitro IL-1ß neutralization, ELISA

B122

BE0246

IL-2

mouse

in vivo and in vitro IL-2 neutralization, in vivo IL-2 receptor stimulation (as a complex with IL-2), ELISPOT, FC

JES6-5H4BE0042

IL-2

mouse

in vivo IL-2 neutralization, in vivo IL-2 receptor stimulation (as a complex with IL-2)

JES6-1A12BE0043

IL-2

mouse

in vivo IL-2 neutralization, in vivo IL-2 receptor stimulation (as a complex with IL-2)

S4B6-1

BE0043-1

IL-3

mouse

in vivo and in vitro IL-3 neutralization, in vivo IL-3 receptor stimulation (as a complex with IL-3), ELISA, FC

MP2-8F8BE0282

IL-4

mouse

in vivo and in vitro IL-4 neutralization, in vivo IL-4 receptor stimulation (as a complex with IL-4), FC

11B11BE0045

IL-4

mouse

ELISA, ELISPOT, FC

BVD6-24G2

BE0199

IL-4

human

in vitro IL-4 neutralization, FC

MP4-25D2

BE0240IL-5mouse/humanin vivo IL-5 neutralization, in vivo eosinophil depletion

TRFK5BE0198

IL-6

mouse

in vivo and in vitro IL-6 neutralization

MP5-20F3

BE0046IL-7

mouse/humanin vivo IL-7 neutralization, in vivo IL-7 receptor stimulation (as a complex with IL-7)

M25

BE0048

IL-9

mouse

in vivo IL-9 neutralization

9C1BE0181

IL-9

human

FC, ELISA

MH9A4BE0327

IL-10

mouse

in vivo and in vitro IL-10 neutralization

JES5-2A5BE0049

IL-12

mouse

in vitro IL-12 neutralization

R1-5D9BE0052

IL-12 p40

mouse

in vivo IL-12p40 neutralization, p40 affinity chromatography, IP, ELISA, FC, WB

C17.8BE0051

IL-12 p70

human

Functional assays, ELISA, FC

20C2BE0234

IL-12 p75

mouse

in vivo IL-12p75 neutralization, ELISA

R2-9A5BE0233

IL-15

mouse

in vivo and in vitro IL-15 neutralization

AIO.3

BE0315

IL-17Amousein vivo IL-17A neutralization

17F3BE0173

IL-17Fmousein vivo IL-17F neutralization

MM17F8F5.1A9BE0303

IL-18

mouse

in vivo IL-18 neutralization

YIGIF74-1G7

BE0237

IL-23 (p19)

mousein vivo IL-23p19 neutralization; WB

G23-8

BE0313IL-27 p28

mouse

in vivo and in vitro IL-27 p28 neutralization, FC

MM27.7B1

BE0326

CCL2 (MCP-1)

mouse/human/rat

in vivo CCL2 neutralization, IHC-F

2H5BE0185

CSF1

mouse

in vitro CSF1 neutralization

5A1BE0204

CXCL9 (MIG)

mouseIFMIG-2F5.5

BE0309

GM-CSF

mousein vivo and in vitro GM-CSF neutralization, FC

MP1-22E9BE0259

IFNγ

mouse

in vivo and in vitro IFNγ neutralization

R4-6A2BE0054

IFNγ

mouse

in vivo and in vitro IFNγ neutralization, ELISPOT, FC

XMG1.2BE0055

IFNγ

human

in vitro IFNγ neutralization

B133.5

BE0235

IFNγ

humanFC

B27

BE0245

IFNγ

mouse

in vivo and in vitro IFNγ neutralization

H22BE0312

RANKL (CD254)

mousein vivo RANKL blockade

IK22/5BE0191

TGF-ß

mouse/human/rat/monkey/
hamster/canine/bovine

in vivo and in vitro TGFß neutralization

1D11.16.8

BE0057

TL1A (TNFSF15)

mousein vivo TL1A neutralization, FC

5G4.2

BE0323

BE0243TNFαmousein vivo and in vitro TNFα neutralization

XT3.11

BE0058TNFαmouse/rat/rabbit

in vivo TNFα neutralization, FC

TN3-19.12

BE0244

IF Immunofluorescence | IHC-F Immunohistochemistry (frozen) | IHC-P Immunohistochemistry (paraffin) | WB Western blot | IP Immunoprecipitation

BP0045BP0051BP0173BP0055BP0057BP0058

Cytokine and Chemokine Receptor Antibodies
α-mouse IL-10R (BP0050)InVivoMab vs. InVivoPlus

α-mouse IFNAR-1 (BP0241)
purity level

InVivoMabInVivoPlus< 2EU/mg< 1EU/mg> 95%> 95%

protein aggregates validated at ≤ 5%IFNAR-1(60 kDa)

azide and carrier protein freeendotoxin concentration

IL-10R (31 kDa)

validated by immunoblot, FC, or ELISA
tested for murine pathogens

Purified IL-10R

Antigen

Reactivity

Purified IFNAR-1

available in bulk quantities

Application

Clone

InVivoMab InVivoPlus
CatalogCatalog

IL-1 R (CD121a)mousein vitro IL-1 R blockade

JAMA-147

IL-2Rα (CD25)

mousein vivo regulatory T cell depletion, FC

PC-61.5.3

BE0012

IL-2Rα (CD25)

humanIP, IF

7G7B6BE0014

BE0256

IL-2Rß (CD122)

mouse

in vitro NK cell negative selection, IP, FC

5H4BE0272

IL-2Rß (CD122)

mouse

in vivo NK cell depletion, in vitro IL-2R blockade, Functional assays, FC

TM-Beta 1

BE0298

IL-6R

mouse

in vivo and in vitro blocking of IL-6/IL-6R signaling

15A7BE0047

IL-7Rα (CD127)

mousein vivo blocking of IL-7Rα signaling, FC

A7R34

BE0065

IL-10R (CD210)

mousein vivo blocking of IL-10/IL-10R signaling, in vitro blocking of IL-10R signaling, FC

1B1.3ABE0050

IL-21Rmouse

in vivo IL-21R blockade

4A9BE0258

c-Kit (CD117)

mouse

FC, IF, IHC

2B8BE0280

c-Kit (CD117)

mousein vivo mast cell depletion, in vivo c-Kit+ cell depletion, in vitro c-Kit neutralization, IP, FC

ACK2BE0293

CCR3 (CD193)

mousein vivo eosinophil depletion

6S2-19-4

BE0316

common γ chain (CD132)

mousein vivo γc blockade, Functional assays, IP, FC

3E12BE0271

CSF1R (CD115)

mousein vivo macrophage depletion, in vitro CSF-R1 neutralization, in vivo monocyte depletion, FC

AFS98

BE0213

CSF1R (CD115)

humanin vitro CSF1R neutralization, IHC-P, Functional assays, FC

2-4A5-4

BE0347CXCR3 (CD183)

mouse

in vivo CXCR3 neutralization, FC

CXCR3-173

BE0249DR5 (CD262)

mousein vivo and in vitro induction of TRAIL-mediated apoptosis

MD5-1

BE0161IFNAR-1mouse

in vivo and in vitro IFNAR-1 blockade

MAR1-5A3

BE0241IFNγR (CD119)

mouse

in vivo IFNγR neutralization

GR-20

BE0029IFNγRα (CD119)mouse

WB, IP, FC

2E2

BE0287

TNFR2 (CD120b)mousein vivo and in vitro TNFR2 blockade

TR75-54.7

BE0247BP0012BP0050BP0213BP0241

Cytokine & Chemokine Secretion Profiles
T Cell

IL-1
IL-2
IL-3
IL-4
IL-6
IL-8
IL-9
IL-10
IL-13

IL-14
IL-16
IL-17
IL-18
IFNα
IFNβ
IFNγ
TNFα
LTα

B CellNK Cell

Neutrophil

IL-1
IL-10
IL-12
IFNα
IFNβ
TNFα
LTα

MIP-1a (CCL3)
MIP-1b (CCL4)RANTES (CCL5)
IFNγ
IL-17A
IL-22
TNFα

TNFα

| FC Flow cytometry (requires flurochrome conjugation)

MacrophageIL-1
IL-6
IL-8
IL-10
IL-12
IL-15
IL-18
IFNα
IFNβIFNγ
TNFαGM-CSF

Eosinophil

Mast Cell

IL-1
IL-2
IL-4
IL-5IL-6IL-8IL-13
TGFβTNFαIL-4IL-5
IL-13
GM-CSF

Antibodies for in vivo research since 1997.

For over 20 years, scientists have trusted Bio X Cell as their go-to source for in vivo functional grade antibodies.
This is reflected in over 15,000 peer-reviewed publications citing Bio X Cell products. We understand this
responsibility is of paramount importance and remain committed to producing antibodies of unparalleled qualityand consistency, enabling our partners around the globe to accelerate research and discoveries.

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