PROCEPT BioRobotics® Announces First Commercial Aquablation Therapy Procedures in Japan
August 22, 2023
REDWOOD CITY, Calif., August 22, 2023 — PROCEPT BioRobotics® Corporation (NASDAQ: PRCT) (“PROCEPT BioRobotics”), a global leader insurgical robotics, announced today that it has successfully completed the first commercial Aquablation® therapy procedures in Japan. The procedures
were carried out at two premier medical institutions, in association with the 100 patient post-market surveillance study. Completing the first commercial
procedures in Japan represents another important milestone in PROCEPT BioRobotics’ global expansion, highlighting the growing acceptance andrecognition of Aquablation therapy as a pioneering solution for BPH patients.
Following the successful procedures at Oita Urology Hospital and Itabashi Chuo Medical Center, Japanese urologist Dr. Masato Fujisawa, Professor,
Division of Urology, Kobe University Hospital, praised the new therapy, "With millions of Japanese men suffering from BPH, the regulatory clearance
and successful completion of Aquablation therapy procedures marks a vital development in improving patient care. Aquablation therapy's uniqueblend of robotic precision and reproducibility sets a new standard in BPH treatment.""We view Japan as a very promising market for the adoption of Aquablation therapy, which has a long history of adopting new, innovative technologies,
while prioritizing patient outcomes. Similar to our approach in the U.S., we intend to pave the way in Japan with solid clinical data and support from key
opinion leaders, setting the stage for a dynamic and lasting commercial success,” said Reza Zadno, PROCEPT BioRobotics’ CEO.
Dr. Shigeo Horie, Professor, Department of Urology, Juntendo University Hospital, commented, "Traditionally, surgeons visualized the prostate througha limited cystoscopic window during BPH procedures. With Aquablation therapy, we complement that view by utilizing real-time ultrasound imaging toview the entire prostate. This, coupled with advanced planning software and automated robotic resection, enables Japanese urologists to provide acustomized treatment option for every patient in a safe and effective manner. Aquablation therapy represents a significant advancement in BPH
treatment, and we are excited to now offer this innovative solution to our patients.”

About Aquablation Therapy
Aquablation therapy is the first and only image-guided, automated, heat-free robotic therapy for the treatment of BPH. The system’s real-time
ultrasound imaging provides the surgeon with a multi-dimensional view of the prostate enabling personalized treatment planning tailored to eachpatient’s unique anatomy. The surgeon can specify which areas of the prostate to remove while preserving the anatomy that controls erectile function,
ejaculatory function, and continence. Once the treatment plan is mapped, the automated robot removes prostate tissue in a precise, targeted, andcontrolled fashion using novel, heat-free waterjet technology.
This novel technology is backed by numerous peer-reviewed publications demonstrating its safety, efficacy, and the durability of its outcomes. The
cornerstone of the data is two, prospective, FDA trials with 5-year data; WATER and WATER II. The WATER study (the U.S. pivotal trial for FDAapproval) randomized Aquablation against TURP, which has been the standard of care for resection of prostates smaller than 80ml, in a doubleblinded study. The trial demonstrated superior safety and comparable efficacy to TURP in prostates 30ml to 80ml in size and superior safety andefficacy in prostates 50ml to 80ml in size. The WATER II study included men with a prostate size greater than 80ml undergoing Aquablation. The study
met its pre-specified performance goal for safety and efficacy. The two, FDA trials with 5-year follow-up have demonstrated consistent results acrossvarious prostate anatomy.
About PROCEPT BioRobotics CorporationPROCEPT BioRobotics is a surgical robotics company focused on advancing patient care by developing transformative solutions in urology.
PROCEPT BioRobotics develops, manufactures and sells the AquaBeam Robotic System, an advanced, image-guided, surgical robotic system foruse in minimally invasive urologic surgery with an initial focus on treating benign prostatic hyperplasia, or BPH. BPH is the most common prostate
disease and impacts approximately 40 million men in the United States. PROCEPT BioRobotics designed Aquablation therapy to deliver effective,
safe and durable outcomes for males suffering from lower urinary tract symptoms, or LUTS, due to BPH that are independent of prostate size andshape or surgeon experience. The Company has developed a significant and growing body of clinical evidence, which includes nine clinical studies
and over 150 peer-reviewed publications, supporting the benefits and clinical advantages of Aquablation therapy.
Forward Looking Statements
This release contains forward‐looking statements within the meaning of federal securities laws, including with respect to the Company’s statements
regarding the potential utilities, values, benefits and advantages of Aquablation therapy performed using PROCEPT BioRobotics’ products, including
AquaBeam® Robotic System, which involve risks and uncertainties that could cause the actual results to differ materially from the anticipated results
and expectations expressed in these forward-looking statements. You are cautioned not to place undue reliance on these forward-looking statements.
Forward-looking statements are only predictions based on our current expectations, estimates, and assumptions, valid only as of the date they are
made, and subject to risks and uncertainties, some of which we are not currently aware. Forward-looking statements may include statements
regarding market opportunity and penetration, installed base growth, commercial momentum, overall business or the overall macroeconomic
environment, which may impact customer spending or the Company’s financial performance. Forward ‐looking statements should not be read as aguarantee of future performance or results and may not necessarily be accurate indications of the times at, or by, which such performance or results
will be achieved. These forward‐looking statements are based on the Company’s current expectations and inherently involve significant risks anduncertainties. Actual results and the timing of events could differ materially from those anticipated in such forward‐looking statements as a result of
these risks and uncertainties. These risks and uncertainties are described more fully in the section titled “Risk Factors” in the Company’s filings withthe Securities and Exchange Commission (the “SEC”), including the Company’s annual report on Form 10-K filed with the SEC on February 28, 2023.
PROCEPT BioRobotics does not undertake any obligation to update forward‐looking statements and expressly disclaims any obligation or undertaking
to release publicly any updates or revisions to any forward‐looking statements contained herein. These forward-looking statements should not berelied upon as representing PROCEPT BioRobotics’ views as of any date subsequent to the date of this press release.

Important Safety Information
All surgical treatments have inherent and associated side effects. For a list of potential side effects visit https://aquablation.com/safety-information/.
Investor Contact:
Matt Bacso, CFA
VP, Investor Relations and Business Operations
m.bacso@procept-biorobotics.com