WHAT DOES U.S.GOVERNMENT RESEARCHTELL US ABOUT BPA?
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In the last several years, federal government scientists have been conducting in-depthstudies to answer key questions about the safety of BPA. To date, more than 20 ofthese studies have been published in the peer-reviewed scientific literature.
Taken together, the results of these studies provide strong support for the safety ofBPA. Based on the government research, along with results from other studies, theU.S. Food and Drug Administration (FDA) recently answered the question:“Is BPA safe?” with a clear answer – “Yes.”EEPPAANLL
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FFDDAACCDDCCKey findings from the research are briefly summarized below:

1.

Consumer exposure to BPA is extremely low.

2.

BPA is rapidly eliminated from the body.

3.

No risk of health effects at typical consumer exposure levels.

1. CONSUMER EXPOSURE TO BPA IS EXTREMELY LOW.
SAFE EXPOSURE LIMITCONSUMEREXPOSURE

2.4
micrograms

1,000xBELOW SAFE

LIMIT

TYPICAL CONSUMER EXPOSURE
TO BPA IS 1,000 TIMES BELOWTHE SAFE LIMIT established bygovernment scientists, including forchildren, adults andpregnant women.

Supporting data: Center for Disease Control and Prevention (CDC)
CDC Biomonitoring Summary – Bisphenol A

BASED ON CDC DATA,TYPICAL HUMAN EXPOSURE TOBPA IS 2.4 MICROGRAMS A DAY.
To put this in perspective, if a small mint
was broken into pieces that eachweighed 2.4 micrograms, it would take
240 years to consume all of the 87,500
pieces at a rate of one piece per day.

A PERSON WOULD HAVE TO
INGEST 1,300 POUNDS OF FOOD
AND BEVERAGES in contact withpolycarbonate plastic
every day to exceed the safe limit.

2. BPA IS RAPIDLY ELIMINATED FROM THE BODY.
When ingested, most of the BPA that is taken in is converted through metabolism in the intestine to a
substance with no known biological activity. Any trace amount of BPA that remains is converted in theliver to the same inactive substance before entering the bloodstream.

2424

WITHIN 24 HOURS, the inactive
substance is eliminatedthrough urine.

NO BPA
DETECTEDIn clinical studies when volunteers
were exposed to much higher levels ofBPA than typical, NO BPA

COULD BE DETECTED IN THEBLOODSTREAM.
Key Sources:
Environmental Protection Agency (EPA)-funded study, conducted by scientists at thePacific Northwest National Laboratory (PNNL), FDA and CDC on BPA metabolism (Toxicological Sciences, 2011)

A series of studies in animal models
conducted in the FDA laboratory
confirm that ALL AGES - ADULTS,CHILDREN AND INFANTS CAN EFFICIENTLY METABOLIZEAND ELIMINATE BPA.

FDA conducted study on BPA metabolism in infant and adult rats (Toxicology and Applied Pharmacology, 2010)
FDA conducted study on BPA metabolism in monkeys (Toxicology and Applied Pharmacology, 2010)

3. NO RISK OF HEALTH EFFECTS AT TYPICAL CONSUMER
researchers recently published results from what
EXPOSURE LEVELS. Government
may be the largest-scale toxicity study ever conducted on BPA.
SAFE EXPOSURE LIMITCONSUMEREXPOSURE

1,000xBELOW SAFE

LIMITNO REPRODUCTIVE OR
DEVELOPMENTAL HEALTH
EFFECTS WERE FOUND at doses

even remotely close to typical consumer
exposure levels.

Because BPA is rapidly metabolized
and eliminated by the body, IT IS

VERY UNLIKELY THAT BPA COULD
CAUSE HEALTH EFFECTS
AT REAL-LIFE EXPOSURE LEVELS.

Key Sources:
FDA conducted study assessing potential for adverse health effects arising from BPA exposure (Toxicological Sciences, 2014)
FDA conducted study assessing BPA estrogenicity (Toxicological Sciences, 2014)

IT IS VERY UNLIKELY THAT BPA

could act as an estrogenic substance inthe human body at these low levels.

Both studies were funded by the U.S. National Toxicology Program (NTP).