KEIO U-cover̲E 05.11.29 7:46 PM ページ 1

Keio University
Annual Report on Research Activities
2004–2005
Design the Future—Toward the Creation of Intellectual Values—

Keio University
Annual Report on Research Activities
2004–2005
21 November 2005
Published by the Center for Research Promotion
2-15-45 Mita, Minato-ku, Tokyo 108-8345 Japan
TEL +81-3-3453-4511
http://www.keio.ac.jp/index-en.html©Keio University 2005

200511.2500.B

Keio University

KEIO U-honbun̲E 05.11.29 7:35 PM ページ 1

Since the first universities were established in Bologna andParis in the 12th century, the mission of the university has
been the creation and accumulation of knowledge. This mission has
traditionally involved maintaining a neutral position in relation tosociety and an outlook that extends beyond short term trends. At a
distance from the unpredictable, changing and market driven
world, universities have been able to devote themselves to thedevelopment of pure knowledge and research, the results ofwhich have played an important role in societal progress.
Universities should reflect the needs of the era, of the country, ofthe local community, and increasingly of the global community as
well. It is clear that we are now facing complex, unprecedentedchanges on a global scale, and as pillars of society, universities are
now expected to play a greater role in contributing to the realworld by providing services to the community. Collaborative partnerships with industry and governments, provision of medical services and health care, and training of tomorrow’s leaders havebeen added to the university’s more traditional roles of creating
and accumulating knowledge.
Imagine the traditional “ivory tower” style university as a circle;
a geometric shape with a single, central focus. Keio University
believes that universities in the 21st century must broaden theircommitments, and can best be represented by an ellipse; a shapewith two equal focuses in dynamic balance with one another.
One of these focuses is remaining neutral from economic society
in order to promote basic research and the ongoing creation of
new knowledge. Economic society is by nature unstable andrapidly changing, so in order for knowledge creation to progressand break ground in new fields, it must take place outside therealm of market driven influences. The other focus is being directly
committed to supporting and contributing to society. The university
has unique resources which, through innovation and collaboration
with community partners, can be put to direct use to improve society.
Keio is taking a variety of steps to realize the University’s“double-focus” vision, including the establishment of theOrganization for Research Advancement and Administration(ORAA). The Organization was set up to further develop crossdisciplinary research activities, as well as collaborative partnerships
with industry, governments and other universities worldwide.
University research activities have always been an importantfactor in societal progress. Thus, it is very important for universities tocommunicate their research activities to the public. Keio’s Annual
Report on Research Activities provides the community with information regarding our strategies and direction, as well as our current
research activities. It is our hope that this Report will give you abetter understanding of what Keio University is doing to accomplish its
double-focus vision and contribute to the advancement of society.
Yuichiro Anzai
President
Keio University

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Keio University
Annual Report
on Research Activities

03

Organization for Research Advancement and Administration (ORAA)

04

Keio University Research Guide: Where to Contact?

05

Research Centers

05

Mita Campus/Hiyoshi Campus

09

Yagami Campus

11

Shinanomachi Campus

13

Shonan Fujisawa Campus (SFC)

15

Shin-Kawasaki Town Campus

17

Tsuruoka Town Campus

19

Nowton Court Keio University

19

Research Institute for Digital Media and Content (DMC)

21

Topics: Partnerships and Collaborations

23

The 21st Century COE Program

27

Toward an Integrated Methodology for the Study of the Mind
—CIRM: Centre for Integrated Research on the Mind—
Development of a Theory of Market Quality and an Empirical Analysis
Using Panel Data

2004-2005

28

Designing toward the Ordering of Political Society in a Multi-culturaland Pluri-generational World
Policy Innovation Initiative: Human Security Research in Japan and Asia

29

Understanding and Control of Life’s Functions via Systems Biology
Function Creation Oriented Life-Conjugated Chemistry30

Optical and Electronic Device Technology for Access Network
Next Generation Media and Intelligent Social Infrastructure

31

Establishment of Individualized Cancer Therapy Based on
Comprehensive Development of Minimally Invasive and Innovative
Therapeutic Methods
Basic Study and Clinical Application of the Human Stem Cell Biology and
Immunology: Approaches Based on the Development of Experimental
Animal Models

32

Integrative Mathematical Sciences: Progress in Mathematics Motivatedby Natural and Social Phenomena
System Design: Paradigm Shift from Intelligence to Life

33

FY2004 Financial Position

34

Research-related Facilities and Libraries

35

Research Funds at Keio University in FY2004

39

Competitive Research Funds

41

Researchers at Keio University in FY2004

43

Technology Transfer

45

Awards for Research Activities, FY2004

48

Index

49

Access Information

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03

Keio University Research Guide: Where to Contact?

Advancement of Research at Keio University

Primary Point of Contact

intellectual property owned by Keio University should be
addressed to the IPC.

Center for Research Promotion (CRP)The Center for Research Promotion (CRP), located on
Mita Campus, acts as a primary point of contact for yourinquiries concerning future industry-government-academia collaboration with Keio University. Please send an e-mail to
the CRP for questions like: “Does Keio have any professors ina specific field of research?” or, “Could we seek advice for thistype of technology from a professor at Keio?” Upon receipt ofyour request, a coordinator at the CRP, or an expert at one of
the relevant organizations at the ORAA will contact you at theearliest convenience.
http://www.crp.keio.ac.jp/(Inquiry forms are available here)
E-mail:crp@keio.ac.jp(See pages 43-44)

Based on “Gakujutsu sendo (leadership for scientificprogress),” Keio University believes that its most importantmission is to return the fruits of its traditional interests in education and research to society. Keio aims at promotinginternationally competitive and creative scientific research inorder to make significant contributions to the 21st century,
thus serving as a driving force for future society.
Keio University was designated for the 21st Century
Centers of Excellence (COE) Program by the Ministry of
Education, Culture, Sports, Science and Technology(MEXT). Winning twelve COE programs, Keio has the highest
number of the COEs of any private university in Japan. In addition, a large number of advanced research projects areroutinely underway at each Keio campus: Mita, Hiyoshi,
Yagami, Shinanomachi, and Shonan Fujisawa. Research
projects at Keio often involve collaborations within thefields of industry, government, and academia. Such
research activities, in the form of commissioned research,joint research, and personnel exchanges, are most distinctively being practiced at the Keio Leading-edge Laboratory of
Science and Technology (KLL) at Yagami, the Center for
Integrated Medical Research at Shinanomachi, Keio
Research Institute at SFC, the Shin-Kawasaki Frontier
Research and Education Collaborative Square (K-FRECS) in
Kawasaki City, and the Institute for Advanced Biosciences in
Tsuruoka City.
The Offices of Research Administration on each campus
at Keio have long provided practical advice and services tosupport individual researchers. Keio was a pioneering university when it established the Intellectual Property Center(IPC) in 1998 as a technology licensing organization (TLO). The
IPC has successfully and proactively sought to protect and utilize research results as identifiable intellectual property
since then. Keio also launched the Organization for
Research Advancement and Administration (ORAA) in
October 2003 to further facilitate a series of research
activities by supporting researchers, generating interdisciplinary and innovative research, and promoting research
returns to society. The foundation of the ORAA completed theimplementation of a mechanism for strategic advancement ofresearch activities for the entire university.

In FY2004, the “Keio Gijuku Policy for IndustryGovernment-Academia Collaboration,” “Guidelines forIntellectual Property at Keio Gijuku,” and “Keio Gijuku
Management Policy for Conflicts of Interest” were enacted
and revised in the Committee of the ORAA.

Roles and Functions of the ORAAThe ORAA is composed of the Center for Research
Promotion, the Incubation Center, the Intellectual Property
Center (IPC), the Intellectual Property Mediation
Committee, the Research Ethics Committee, etc. It formulates
the university’s overall strategy for cooperation with industry,
government, and academia, from the start of planning to
the end of returning the results to society. The major roles andfunctions of each organization in the ORAA are as follows.
The Center for Research Promotion is an organization dedicated to planning and promotion of comprehensive research projects. More specifically, it: (1) plans andpromotes comprehensive and strategic projects with its
own surveys and resources; (2) collects the newest information on research grants and subsidies and provides it toresearchers; and (3) serves as the university’s primarycontact point for all inquiries and proposals for industrygovernment-academia collaborations. To realize its mission, theCenter cross-sectionally cooperates, under the guidance of theAdvisory Board, with other organizations in the ORAA,
namely, the IPC, the Incubation Center, and the Offices of
Research Administration.
The Incubation Center is an organization with theobjective of supporting and advancing incubation activities oftransferring research results nurtured at Keio University tosociety. It was established to create university ventures byfurther vitalizing activities between industry-governmentacademia collaborations. As a start, an incubation facility
called “Keio Fujisawa Innovation Village” will be completed by the end of FY2005 at the Shonan Fujisawa
Campus under the “Keio University Collaborative
Entrepreneur Development Program.” The Innovation
Village will be co-managed by the Organization for Small andMedium Enterprises and Regional Innovation JAPAN(SMRJ), Kanagawa Prefecture, and Fujisawa City.
The Intellectual Property Center (IPC) is atechnology licensing organization with a range of responsibilities, from management and operation of intellectual
properties to facilitating cooperation with society. Uponthe request of an inventor, the IPC closely examines
patentability and the potential for licensing considering theinventor’s concept for practical applications, makes selections,files an application for a patent, and manages its maintenance. Such activities of the IPC lead to an increased
chance of licensing, producing startups, and promoting
joint research projects with companies for commercialization.
Inventors at Keio University may lodge objections
regarding patent applications with the Intellectual
Property Mediation Committee. The Research Ethics
Committee, on the other hand, deals with and keeps every
party well informed of rules and regulations concerning
not only intellectual properties but also research ethics,
conflicts of interest and duties, dual employment, andmaintenance of confidentiality at Keio at large.
The Offices of Research Administration locatedat the five campuses, being most close to researchers, provide
practical support and services according to researchers’
daily needs and also work with organizations within the
ORAA. The Offices provide official information on sources ofresearch, facilities environments, and opportunities for
subsidies from within and outside the university, and provide
a variety of services including support for negotiating andconcluding contracts for joint or commissioned research,
management of research expenses and research spaces,
and compilation and presentation of research results.
Furthermore, the Head Office of Research
Administration functions as an umbrella to integrate the
Offices of Research Administration on each campus, the
K-FRECS, and the Center for Integrated Education
System which supports primary and secondary education at
Keio Gijuku. The Head Office shares and compiles information
on campus research and researchers through development
and maintenance of a research database. It is also responsible for supporting transmission of research results from
Keio, as in the “Symposium on the 21st Century COE
Programs adopted in 2002: Interim Report.”

Organization for Research Advancement and Administration (ORAA)
Shinanomachi Office of Research Administration
Shonan Fujisawa Office of Research Administration
Center for Keio Frontier Research and Education Collaborative Square (K-FRECS)
Center for Integrated Education System

Yagami Office of Research Administration
Hiyoshi Office of Research Administration
Mita Office of Research Administration
Head Office of Research Administration
Offices of Research
Administration

Research Ethics CommitteeIntellectual Property Mediation Committee

Research Achievements Database for the School of
Medicine
http://www.med.lib.keio.ac.jp/kenkyudb/

http://www.ipc.keio.ac.jp/
E-mail: toiawasesaki-ipc@adst.keio.ac.jp

Keio Leading-edge Laboratory of Science andTechnology (KLL)
http://www.kll.keio.ac.jp/

Keio Leading-edge Laboratory of Science andTechnology (KLL) Liaison Office
The Liaison Office of Keio Leading-edge Laboratory of
Science and Technology (KLL) on Yagami Campus responds
directly to inquiries regarding research projects conducted in
the Graduate School of Science and Technology.

Keio Research Institute at SFC
Visit the website for information on research projects at
the Shonan Fujisawa Campus.
(See pages 13-14)

http://www.kri.sfc.keio.ac.jp/english/index.html(See pages 9-10)04

http://www.kll.keio.ac.jp/liaison/index.html
E-mail: liaison@educ.cc.keio.ac.jp

Frontier Research and Education Collaborative
Square in Shin-Kawasaki (K-FRECS)
Visit K-FRECS website for research projects andactivities on Shin-Kawasaki Town Campus.

Websites
Other Contacts
Intellectual Property Center (IPC)
The Intellectual Property Center (IPC), also located on
Mita Campus, has technology transfer managers specializingin legal matters, intellectual property management, engineering, and biology. The managers will provide consultation
and assistance in licensing and contract negotiations forstartups, technology transfers, etc. Any inquiries in regard to

Research information is also available in the following
websites.

(See pages 15-16)

Keio Researchers Information System (K-RIS)
Information on Keio researchers, except for
researchers at the School of Medicine, is available on
the K-RIS database.
http://www.k-ris.keio.ac.jp/index_en.html

Tsuruoka Town Campus
Visit the website of Tsuruoka Town Campus of Keio
(TTCK) for information on biology research conducted in
the Institute for Advanced Biosciences on campus.

http://www.k2.keio.ac.jp/(See pages 17-18)

http://www.ttck.keio.ac.jp/

Events
FY2004 (April–March)
DD/MM/YY

Event

Host

Site

17, 19/04/04

Symposium on the 21st Century COE Programs adopted in FY2002: Interim Report

Head Office of Research
Administration

Mita Campus

21-22/04/04

Venture Private ConferenceIntellectual Property Center

Mita Campus

22/06/04

The 3rd Technology Transfer Forum in Kyushu

Intellectual Property Center

Venue in Fukuoka

27-28/08/04

Bio Finance Guild 2004 (held consecutively since FY2002)

Nikkei BP,
Tsuruoka Town Campus

Venue in Tokyo

24/09-25/11/04

Introduction to Bioscience for Tsuruoka Citizens (held consecutively since FY2001)

Tsuruoka Town Campus

Tsuruoka Town Campus

02/10/04

Open Campus 2004 (Shin-Kawasaki)

Shin-Kawasaki Town Campus

Shin-Kawasaki Town Campus

02/10/04-

Open Seminars and Lecture Series (eight lectures on Saturdays) at K2

Shin-Kawasaki Town Campus

Shin-Kawasaki Town Campus

23-24/11/04

SFC Open Research Forum 2004

Shonan Fujisawa Campus

Roppongi Hills, Tokyo

03/12/04

The 5th Keio Techno-Mall

KLL

Tokyo International Forum

08-09/12/04

Venture Private ConferenceIntellectual Property Center

Mita Campus

28/01/05

Keio Symposium for Leading-edge Science and Technology: Frontier of Bioscience
Research and Outlook for Practical Application of its Technology

Center for Research Promotion

Mita Campus

25/02/05

The 1st Keio Innovation NetworkIntellectual Property Center

Mita Campus

DD/MM/YY

Event

Host

Site

9, 16/04/05

Symposium on the 21st Century COE Programs adopted in FY2003: Interim Report

Head Office of Research
Administration

Shinanomachi Campus andMita Campus

FY2005 (April–March)

21/04/05

The 2nd Keio Innovation NetworkIntellectual Property Center

Mita Campus

10-11/05/05

Venture Private ConferenceIntellectual Property Center

Mita Campus

27/05/05

The 3rd Keio Innovation NetworkIntellectual Property Center

Mita Campus

28/06/05

The 4th Keio Innovation NetworkIntellectual Property Center

Mita Campus

23/07/05

Center for Research Promotion Symposium “Design the Future: IT Returns to the People”

Center for Research Promotion

Mita Campus

26/07/05

The 5th Keio Innovation NetworkIntellectual Property Center

Mita Campus

31/08/05

The 4th Technology Transfer Forum in OsakaIntellectual Property Center

The Osaka Chamber ofCommerce and Industry

Prof. Yoshiaki Kobayashi (Mita)
Prof. Yasuhiro Koike (Yagami)
Prof. Toshio Suda (Shinanomachi)
Prof. Jiro Kokuryo (SFC)

12/11/05

Open Campus 2005 (Shin-Kawasaki)

Shin-Kawasaki Town Campus

Shin-Kawasaki Town Campus

22-23/11/05

SFC Open Research Forum 2005

Shonan Fujisawa Campus

Roppongi Hills

02/12/05

The 6th Keio Techno-Mall

KLL

Tokyo International Forum

Organization for Research Advancement andAdministration (ORAA)

01/02/06

Keio Symposium for Leading-edge Science and Technology

Center for Research Promotion

Mita Campus

Intellectual
Property Center

Incubation
CenterCenter for
Research Promotion

Advisory Board* Listed here are events implemented by the ORAA, or related events at the campus level. There are many other events scheduled and hosted by various research institutes. For details, see the website of each research
institute.

Organization for Research Advancement and Administration (ORAA)/Keio University Research Guide: Where to Contact?

Keio University Annual Report on Research Activities 2004–2005

Organization for Research Advancement and Administration (ORAA)KEIO U-honbun̲E 05.11.29 7:35 PM ページ 5

Research Centers

Mita Campus/Hiyoshi Campus
Pathways to the Future for Humanities, Social Science,and Natural Science: Centers for Comprehensive
Research and Education

05

Fukuzawa Memorial Center for Modern Japanese Studies

Keio Economic Observatory wasestablished in 1959 on the occasion of
the 100th anniversary commemoration of
Keio University. Since then, we work forthe purpose of conducting theoreticaland empirical research on economic andindustry studies in the context of theexisting economic conditions of Japan.
Our institute consists of the three
sections: Economics, Law and Behavioral
Science. In the 2004 fiscal year, we carriedout various projects as follows;• the research of economic law• the human resource management• the method of a personnel evaluation• the flow of funds analysis• the Input-Output analysis about environmental problems• the compilation of the regional Input-Output table• the productivity analysis• the economic analysis of uncertainty.
These research achievements are published as KEO Discussion Paper and some ofthese papers are released in the following URL.
http://www.sanken.keio.ac.jp/index_e.html

This center is being active to achieve
three purposes. The first is a role as theschool archives, to collect, pigeonhole andsafekeep the historical documents and data
about Yukichi Fukuzawa and Keio Gijuku.
The second is a role as the research instituteto study about modern Japanese history,
placing Yukichi Fukuzawa or Keio Gijuku in theeyesight. Then, the third is a role as theeducation organization to transmit the results, which were gotten through the activity of the two
above, to the student and the widely general people by the lecture, seminar and so on.
Moreover, in 2004, it has set about compiling the 20 volumes of Collection of Materials
about Keio Gijuku’s 150 Years History, to commemorate the anniversary year of Keio.
http://www.fmc.keio.ac.jp/

Mita Campus
Faculties (undergraduate)• Institute of Cultural and Linguistic Studies● Graduate School of Letters• Institute for Media and Communications Research● Graduate School of Economics• Keio Economic Observatory● Graduate School of Law● Graduate Schools

Shinanomachi Campus• The Shido Bunko, The Institute of Oriental Classics● Graduate School of Human Relations• International Center● Graduate School of Business and Commerce• The Teacher Training Center● Law School● Graduate School of Medicine• Fukuzawa Memorial Center for Modern Japanese Studies• Institute of East Asian Studies● School of Medicine• Center for Japanese Studies• Research Center for the Arts and Arts Administration• Global Security Research Institute• Research Institute for Digital Media and Content● Faculty of Letters● Faculty of Economics● Faculty of Law● Faculty of Business
and Commerce

Research Centers on the Mita and Hiyoshi Campuses

Hiyoshi Campus● Graduate School of Business Administration• Institute of Physical Education• Keio Research Center for the Liberal Arts
• Keio Research Center for Foreign Language Education• Health Center• Sports Medicine Research Center

English Section Research Room
German Section Research RoomFrench Section Research Room
Chinese Section Research RoomSpanish Section Research Room
Other Languages Section Research Room
Humanities Section Research RoomSocial Sciences Section Research RoomAstronomy and Geography Section Research Room

Yagami Campus● Faculty of
Science andTechnology● Graduate School of Scienceand Technology

Mathematics Section Research Room
Anthropology Section Research Room
Center for Research on the Arts
Center for Music ResearchCenter for Psychology ResearchCenter for Research on Biology
Center for Research on ChemistryCenter for Research on Physics

Institute of Cultural and Linguistic Studies

Institute for Media and Communications Research

The Institute of Cultural and
Linguistic Studies is an academic institution, independent from the University
faculties. The Institute investigates thenature of human cognitive capacities
and socio-cultural interactions, adopting
an interdisciplinary approach acrosshumanities, social sciences, and naturalsciences. Currently, a permanent faculty ofthe seven scholars, specialized in theoretical linguistics, typological linguistics, psycholinguistics, philosophy of language,
Hellenistic literature, Islamic thought, and Vietnamese history, guides the direction of theresearch projects at the Institute, bringing together faculty members with common interest
broadly from all the schools of the university. An outcome of the ongoing projects isreported in the Institute’s annual bulletin, Reports of the Keio Institute of Cultural and
Linguistic Studies, and major results are published in its monograph series. The Institute alsooffers a range of language courses at undergraduate and graduate level, including
Akkadian, Arabic, Cambodian, Egyptian, Hebrew, Korean, Persian, Sanskrit, Thai,
Turkish, and Vietnamese.
http://www.icl.keio.ac.jp

The Institute for Media andCommunications Research promotes research projects financed byits own research funds as well as
special donations to the Institute.
During FY2004, the Institute continued
to support the following four
research projects: “Media Stereotyping,”“Power and Journalism,” “Internet
Development and Civic Culture in
Japan,” and “Content Distribution in the Asia and Pacific Regions.” In addition to theseresearch projects, which were launched several years ago, the Institute has functioned
since 2003 as a research unit for a large research project entitled the 21st Century COE
Program, funded by the Ministry of Education, Culture, and Science (MEXT). The results of theseresearch projects were published in the Japanese language journal, Keio Media andCommunications Research, No. 55, 2005. 3 and the English language journal, Keio
Communication Review, No. 27, 2005. 3. These journals are available as well (See theinstitute’s URL below). A series of books entitled the Dynamics of a Civic Society in a
Multicultural World consisting of a total of 15 volumes were published as a result of the
21st Century COE Program. The 14th and 15th volumes were published by the
researchers of our Institute.
http://www.mediacom.keio.ac.jp/

Shido Bunko, Institute of Oriental Classics
The Shido Bunko, or the Instituteof Oriental Classics, is an attachedinstitution with a director, six faculty
members and four researchers by contract at Keio University. The work comprises the investigation of Japaneseand Chinese classical materials athome and abroad, the collection andarrangement of materials microfilmedand digitalized, and the research by thebibliographical method.
The Shido Bunko received a research grant (a special area studies A of Grant-in-Aid for
Scientific Research) from the MEXT in 2004 academic year for “the research on Japanese andChinese dictionaries and encyclopedias.”
The Shido Bunko is even a professional library for public with 140 thousands volume ofbooks and six thousands reels of microfilms.
Otherwise, the Shido Bunko has three “Shido Bunko Seminar” for graduate students tolearn about the bibliographical method using rare materials in spring and autumn in each term.
Moreover, the Shido Bunko opens a lecture once a year. The lecture, a title of ”A
genealogy on the knowledge of miscellaneous matter from Dunhuang manuscripts to printing
book in the Republic of China” by Professor Tokio Takada of the Institute for Research in
Humanities at Kyoto University was held in December first in 2004 academic year. Shido Bunko
Ronshu (The Shido Bunko Journal) No. 39 issued in February 2005 contains six articles and two
bibliographies as research results.
http://www.sido.keio.ac.jp

06

Keio Institute of East Asian Studies (KIEAS)
The Keio Institute of East AsianStudies (KIEAS) has four research projects
simultaneously each year. Four projects
were conducted in 2004: Globalism,
Regionalism and Localism in Asia,
Influences of America’s Judicial Review in
Asia, One Hundred Year since the RussoJapanese War and Political Order inSoutheast Asia. Each project presented its research achievement at the academic forum
which was annually held in the institute. In 2004 the institute held international conferences such as Japan-Korea Security Dialogue, Japan-Korea Four University’s President
Meeting and Symposium on Japan-China Relationship. The institute also hosted biannual
Lecture Series on East Asia. Last year altogether eleven specialists delivered speeches
about various aspects of East Asia. It will be published as a book, soon. Please check at our
homepage which provides you all kinds of activity information in the institute including
other seminars and lectures.
http://www.kieas.keio.ac.jp

Center for Japanese Studies
The Center for Japanese Studies offers Japanese
language and Japanese Studies courses to international
students. In addition, research on various topics related tosecond-language education is carried out, as well as educationof Japanese language teachers.
The Center is in charge of the Japanese language andculture courses offered at the university, and of the 180
students, coming from more than 30 countries and regions,who participate in the Japanese Language Program. It also
holds Japanese language courses for the international students
enrolled at the undergraduate and graduate levels, and various
courses for those who participate in the Program for
Teaching Japanese as a Foreign Language.
http://www.ic.keio.ac.jp/nncenter/

International Center
The International Center is at thecore of Keio University’s international
activities. It has concluded agreementswith different universities in the world,
and is in charge of sending every year
numerous students and scholars abroad,as well as welcoming those coming to
the university.
The Center provides support tointernational students on both academic
and lifestyle levels, and is also in charge of exchange programs and overseas short-term
research programs. For that purpose, it holds information sessions on studying abroad in general,and also provides information on exchange programs.
In addition, in the International Studies and Japanese Studies courses, various lectures and seminars on international and Japanese culture, history, politics and economics are
conducted in English, in order for both international students and Japanese students tounderstand different cultures. Research on intercultural communications is also conducted.
http://www.ic.keio.ac.jp/

Research Center for Arts and Arts Administration
The Research Center for Arts andArts Administration at Keio University is a
research center which pursues art activities such as fine art, architecture, music,
literature, theatrical play, cinema, dance
activities, and their cultural sensitivity inthe contemporary society with synthetic
and academic stance.
The staff members, faculty members
at Keio University and museum curators in cooperation with experts outside of Keio
University are developing crossover activities such as seminar, lecture, exhibition, performance,
workshop, case study for art management and construction for artists archives. Theirnovel studies have brought fruitful results.
In 2004, the Center hold the lecture, “Vitra Design Museum and Centre PompidouMetz,” Butoh performance, workshops and series of lectures. Also the Center published
ANNUAL REPORT 11, News Letter ARTLET No. 22, CAD and Design, ARTLET No. 23, Art
Therapy and its Environment and BOOKLET No.13, Architectural Space as Memory: Isamu
NOGUCHI, Yoshiro TANIGUCHI, and Keio University.
http://www.art-c.keio.ac.jp/

Research Centers—Mita Campus/Hiyoshi Campus

Keio University Annual Report on Research Activities 2004–2005

The Mita Campus is home to undergraduate faculties in the humanities and social sciences (primarily for junior and senior students), graduate schools
and independent research institutions. The Hiyoshi Campus houses undergraduate faculties in the humanities, social sciences and natural sciences(primarily for freshman and sophomore students), research institutions, and the Graduate School of Business Administration (Keio Business
School). Following is an introduction of research institutions located in these two campuses.

Keio Economic Observatory

KEIO U-honbun̲E 05.11.29 7:35 PM ページ 7

Research Centers
Keio Research Center for the Liberal Arts

Institute of Physical Education wasestablished in 1961, as the organization forresearch and education associated withphysical education and sports. It promotes
the extensive researches for the mechanismthat physical activities contributed to mental
and physical development and health, theteaching theory related to physicaleducation and sport science, and theanalysis of competitors’ performance from.
The research results have been crowned with great success to students, faculties,
student-athletes, or residents in Hiyoshi community throughout the extension course/lecture.
http://www.hc.keio.ac.jp/ipe/

The Keio Research Center for Foreign
Language Education serves the needs ofstudents and faculty members across all
Keio University campuses and affiliatedschools. The Center provides foreign
language education, research, and service. In
terms of education, we provide specializedclasses such as those that prepare students
for standardized tests, advanced classes,
classes that focus on particular skills, andother classes that the individual Faculties are unable to provide. Our goal is to supplement
the language classes provided by the various Faculties. In terms of research, we currently
have four projects aimed at improving foreign language education: (1) Policy Discussion
Forum, (2) Self-study/ICT Development Team, (3) English Placement Development Team, and(4) K-12 English Forum. In terms of service, we provide a variety of lectures, workshops, andstudy abroad programs.
http://www.fcenter.keio.ac.jp

Health CenterSports Medicine Research Center

Our institute is the center which performs medical studies concerning the
support and improvement of daily healthfor the students from elementary school topostgraduate school and school staff.
To pupils under 15 years of age, thefull-time pediatricians are doing clinicalresearches for growth, obesity, anorexia
nervosa, infectious disease and the prevention of future lifestyle-related disease and sudden death etc. To students from 16
years of age and school staff, the full-time internists are doing various researches using theopportunity of an annual checkup. In lifestyle-related diseases, clinical studies aremainly performed about the genotypes relevant to a disease, metabolic syndrome, insulin
resistance, hypertension, diabetes mellitus, hyperlipidemia, bone metabolism, and fatty liver.
Concerning respiratory diseases, we are doing the examination of bronchial asthma, nonsmoking instruction, and the evaluation of a new diagnostic method for tuberculosis(anti-tubercle bacillus antibody). We are also examining the usefulness of plasma BNP
concentration measurement for diagnosing new cardiac disease. Moreover, even in themental side, opinion poll about a psychiatric disorder and investigation about maladjustment
are conducted by the full-time psychiatrists.
Our data are positively publishing in several international societies besides publicationof each domestic special societies every year.
http://www.hcc.keio.ac.jp/

Founded in 1988 at Hiyoshi campus,
Research and clinical activity are now conducted in the sports medicine and science
under the first theme of health. As thestudy commissioned by industry, this instituteis conducting from a collaboration Schoolof Medicine and Faculty of Science andTechnology. Subjects for joint research are
now conducted on SET (Safety Exercise
Threshold) and EMS, and functional sportswear in the sports medicine and scienceand human engineering ergonomics. And clinical study is conducted on the exercise guide forthe evaluation of physical activity and the primary prevention for health related diseases.
http://www.hc.cc.keio.ac.jp/sports/

Keio Research Center for the Liberal
Arts was founded in July 2002 in order tosearch for the ideal form and contents of
the “liberal arts” to pass down to following generations. Thus far, it has conductedvarious full-fledged research and analyses,
suggested new systems or curricula basedon the proposals brought about by the
research, and examined the educational
efficacy of those proposals through experimental classes and induction courses.
There are three research programs conducted by the center: “Core Research
Program,” “Specialized Research Program,” and “Individual Research Program.” The “CoreResearch Program,” which has been focusing on the curricula of Keio University, hasinvestigated the actual situation of the cross-departmental general education courses at
Hiyoshi campus and, in 2004, produced the report The Status Quo and Issues Concerning the
Cross-Departmental General Education Courses at Hiyoshi as a proposal for an alternative
systematic curriculum. The “Specialized Research Program” also published its final reports on“Multi-lateral research on Meta-representative Culture” as a part of the Academic Frontier
Promotion Projects under the Ministry of Education, Culture, Sports, Science and Technology.
The center has also actively exchanged their opinions and worked with other academic
institutions in Japan and outside of the country.
http://www.hc.keio.ac.jp/lib-arts/

Global Security Research Institute (G-SEC)
Global Security Research Institute(G-SEC), established in June 2004, has set up 3
Core Research Subjects to be undertaken by
the end of the 2009 academic year. Under
their umbrella, specific research projects will be
implemented systematically and strategically,
and the achievements will be reported in G-SEC
Working Papers.

07
Keio University Annual Report on Research Activities 2004–2005

I. Studies on Global Innovation Systems
Setting up the interactions between socioeconomic factors and technological innovations as the research subject, the project analyzes theoretically and empirically, theeffects of science and technology policies of a State on economy and society, R&D
efforts in the private sector on corporate growth, economic development and changes in trade
structures. Also delving into human resource development, technological innovation will beenvironment protection, a comparative index of international competitiveness on innovationis created and applied to examine the innovation potentials of Japan.
II. Studies on Asian Security System
This project analyzes empirically and theoretically the characteristics of the security
environment of East Asia, including conventional security issues as well as emerging security
concerns. It involves (1) building a database on security-related issues in the region, and (2)establishing a dialogue community among intellectuals and policy makers, and will explore policy
alternatives for the formation of a more reliable security system in East Asia.
III. Studies on Emerging Crisis for Human Security
Employing the precise monitoring of time and space regarding various risks and crisis
from the past to present at the regional and global environmental levels, this project
involves (1) building of a spatiotemporal database on human security, (2) systemization ofcrisis studies with the viewpoint of human security and (3) designing of alert systems andpolicy authoring tools regarding human security.
http://www.gsec.keio.ac.jp/

Research Institute for Digital Media and Content (DMC)
The Research Institute for DigitalMedia and Content (DMC) was establishedin 2004 under a Japanese governmentfunded program to encourage the development of strategic research centers. The
institute promotes the creation of contextual
digital content. The DMC is engaged in thedevelopment of research, the advancementof international distribution, and thecultivation of personnel resources, in conjunction with other institutions. Through the
DMC, Keio University aims to transform the way knowledge is provided to society as well as
to support the changing modes of intellectual interaction. This will enhance Japan’s leadingrole as a knowledge-generating nation in contributing to the knowledge of a global society(See pages 19–20).
http://www.dmc.keio.ac.jp/

Teacher Training Center
The Teacher Training Center has acted as a Keio-wide
magnet to attract educational and scholarly activities in allareas of school education. The center provides a teacher-training
course for college students who intend to be high school teachers,
and has produced many competent teachers since its foundation in
December 1982. It is not only a “teacher’s college” but also a
research institute for teacher education in Keio University;
accordingly several research projects regarding educational
issues are carried out in the center. In connection with the projects,
open seminars are held every year. In addition the center
emphasizes recurrent education for in-service teachers, and therefore provides the open
summer seminars for teachers every summer and other occasion of in-service training.
http://www.gakuji.keio.ac.jp/etc/kyoshoku/

Institute of Physical Education

Books and Journals (in Japanese)
Institute of Cultural and Linguistic Studies
Reports of the Keio Institute of Cultural and Linguistic Studies, No. 36
Michio Takahashi, Hellenistic Poetry and Homer. Studies on Apollonius Rhodius(March 2005)

Institute of East Asian Studies
Ryosei Kokubun, Rethinkings of China’s Cultural
Revolution (2003)
Motoaki Akagawa, Frontier of East Asian Economic
Studies (2004)
Newsletter of the East Asian Economic Studies(serial publication)

Institute for Media Communications Research
Research Institute Bulletins
Keio Media Communication Research, No. 55 (March 2005)
English Bulletin: Keio Communication Review, No. 27
21 COE-CCC Dynamics of Civil Society in a Multicultural World, Vols. 14-15

Center for Japanese Studies
Nihongo to Nihongo Kyoiku (Japanese and Japanese
Language Education)

Keio Economic Observatory
Library of Keio University Sangyo Kenkyujo
Keio University Sangyo Kenkyujo Selection
KEO (Keio Economic Observatory) Discussion Papers

Research Center for the Arts and Arts Administration
Annual Report, No. 11
ARTLET 22: CAD & Design
ARTLET 23: Art Therapy and its Environment
BOOKLET 13:—Architectural space as memory:
Isamu NOGUCHI, Yoshiro TANIGUCHI, and Keio University

The Shido Bunko, The Institute of Oriental Classics
Shido Bunko Ronshu (The Shido Bunko Journal), No. 39
The Teacher Training Center
Annals of the Teacher Training Center Keio University
Fukuzawa Memorial Center for Modern Japanese Studies
Study on Modern Japan, Vols. 1 (1984)-21 (2004)
Newsletter of Fukuzawa Memorial Center for Modern Japanese Studies (published biannually)
An Inclusive List of the Letters by Yukichi Fukuzawa

Graduate School of Business Administration
The Graduate School of Business Administration of Keio University has several programs including two-year MBA program, Ph.D. program, and executive seminars
held under the name of the “Keio Business School.” We are committed to promoteadvanced business researches with emphasis on practical application of the results.
We have unique properties in our research. First, our school adopts “casemethod” for teaching purpose in class, in which real business problems are identified
and investigated. Faculties are encouraged to write case studies, and led to conduct
researches in such a way to promote business education.
Second, we have accumulated unique research results in specific majors andfields such as marketing, human resources and organization behavior, medical andpharmaceutical researches, and technology management.
We have several cross-faculties researches. For example, in 2004, faculties conducted
researches on “searching for Japanese business management to achieve global competitiveness.” Other faculties established research project on “structural reform ofJapanese corporation” in which various seminars are held regularly. As commissioned
study, our school is chosen as a center of“Management of Technology, Human
Resource Development Program” of Japan
Ministry of Economy, Trade, and Industry.
http://www.kbs.keio.ac.jp/index-e.html

A Literary Magazine Mita Bungaku
Library and Information Science
Journal of Arts and Letters
Mita Journal of Economics
Keio Economic Studies
Journal of Law
Kyoyo-Ronso (Journal of Liberal Arts, Faculty of Law)
(supplementary volume of Journal of Law)
Keio Law Review
Keio Journal of Politics
Journal of Law and Political Studies

Keio Research Center for the Liberal Arts
Research Center for the Liberal Arts Booklet
Graduate School of Business Administration (KBS)Keio Business Forum• Hiyoshi Review
Hiyoshi Review
http://review-keio-up.co.jp/

Studies in Sociology, Psychology and Education
BC Mita Business Review
Keio Business Review

Global Security Research Institute (G-SEC)
G-SEC Working Paper SeriesInstitute of Physical Education
Bulletin of the Institute of Physical Education• Journals Issued by Faculties andAcademic Associations on Mita Campus

Health Center
The Bulletin of Keio University Health Center
Inform Yourself to Your Health

Shigaku (The Historical Science)
Philosophy

Sports Medicine Research Center
Bulletin of the Sports Medicine Research Center

Keio Research Center for Foreign Language Education
Keio Journal of Foreign Language Education

For Inquiries:
Mita Campus
2-15-45 Mita, Minato-ku, Tokyo, Japan 108-8345
Tel: +81-3-3453-4511
Hiyoshi Campus
4-1-1 Hiyoshi, Kohoku-ku,Yokohama-shi, Kanagawa,Japan 223-8521
Tel: +81-45-563-1111

08
Research Centers—Mita Campus/Hiyoshi Campus

Keio Research Center for Foreign Language Education

Mita Campus/Hiyoshi Campus

KEIO U-honbun̲E 05.11.29 7:35 PM ページ 9

Research Centers■ KLL Specified Research Projects (FY2004)

Yagami Campus
Aspiring and Working for the Next Frontiers of
Science and Technology

Started in FY2002

Started in FY2004 (Research to Explore Next-generation Cutting-edge Areas)“The Development of Artificial
Gene-regulation Molecules and its
Application to Post-genome Industry”
Professor Kazunobu Toshima
Fundamental Science and Technology“Development of Metallic
Biomaterials with Bioactive Surface”
Associate Professor Jun Komotori
Integrated Design Engineering“High Speed RF Chip with Spread
Spectrum Modulation”
Associate Professor Yukitoshi Sanada
Integrated Design Engineering“Simulation Method for Prediction of
Explosion Damage”
Associate Professor Akiko Matsuo
Science for Open and Environmental
Systems“Development of Style Design
Emerging Methodology Based on
Digitized KANSEI Information”
Professor Hideki Aoyama
Integrated Design Engineering“Generation of Quantum Entangled
Light and its Transmission and
Quantum Processing”
Professor Fumihiko Kannari
Integrated Design Engineering“Development of the Next Generationof Microfluidic Device for Selective
Separation of Specific Material”
Associate Professor Yohei Sato
Integrated Design Engineering“Optical Detection of a Single Pair ofCharge-transfer Molecules for
Angstrom Resolution Bioimaging”
Associate Professor Toshiharu Saiki
Integrated Design Engineering“A New e-Learning Paradigm Basedon Natural Language Processing”
Associate Professor Hiroaki Saito
Science for Open and Environmental
Systems

Started in FY2003

09“Studies on Regulatory Mechanism ofGrowth Factor Receptor Expression
and Their Application for Genomebased Drug Discovery”
Professor Masaya Imoto
Fundamental Science and Technology

The Faculty and Graduate School of Science and Technology are located at the Yagami Campus, where research and education centered on
scientific and technological fields are conducted. In accordance with the principle of pursuing “emerging” themes, work on campus will continue tobe more open and multifaceted, in the form of joint studies into various issues in as-yet-unknown interdisciplinary areas that go beyond conventional
fields of specialization. Our mission is to foster human resources; to have researchers not only study the leading edge, but also open it up for themselves
and become leaders of society.
http://www.st.keio.ac.jp/english/index.html“Countermeasures on Heat Island by
the Development of Urban Regeneration”
Professor Shuzo Murakami
Science for Open and Environmental
Systems“Molecular Evolution of Peptides toInhibit the Influenza Virus Infection”
Professor Toshinori Sato
Fundamental Science and Technology

10
Research Centers—Yagami Campus

Keio University Annual Report on Research Activities 2004–2005

Faculty/Graduate School of Science and Technology“Development of a Bacteria-based
Computer and its Application to Gene
Analyses”(Change of research topic from April 2005)
Professor Yasubumi Sakakibara
Fundamental Science and Technology

Keio Leading-edge Laboratory of Science and Technology (KLL)The Keio Leading-edge Laboratory of Science and Technology (KLL), a stage for industry-governmentacademia collaboration, was established at the Graduate School of Science and Technology in 2000 asa center for leading academic research and new business creation in science and technology. Its goal
is to return research achievements to society and to conduct research activities that transcendareas of specialization. The KLL has promoted and advanced research projects which are based on theoriginality of Keio University and take advantage of its strength as a comprehensive university.
http://www.kll.keio.ac.jp
Here is an introduction to activities of the KLL.

Activities of the KLL■ Number of Commissioned Research and Other Cases
Received (FY2000–FY2004)■ KEIO TECHNO-MALL 2004

Cases

300

250
52

57

57

53

167

149

139

127

118

35

61

64

72

89

43

200

150

Coordination for Research Work

Fosterage of Young Researchers

The KLL acts as a point of contact between Keio University and groups
outside of Keio University such as industrial circles, promoting cooperation forresearch work in the pre-patent period, or sprouting time. It promotes theresearch activities of the Yagami Campus from various perspectives (seehttp://www.kll.keio.ac.jp/), flexibly responds to individual consultations, andestablishes an interactive flow between enterprises and university research
activities. By utilizing these dynamics, the KLL coordinates optimal joint andcommissioned research projects.

In order to foster outstanding
researchers in science and technology
areas, the KLL offers research aid in theform of the Research Grants for Doctoral
Program, which assists research activities
performed by students in the doctoral
program. In FY2004, the KLL extended
grants of ¥300,000 each to 121 students,
thereby financially assisting the start ofresearch activities by the students as bonafide researchers.

100

Promotion of Research Activities
With the objective of focusing on the development of “germinating”
research areas that are expected to be important to society in the future, the KLL
calls for research projects (“KLL Specified Research Projects”), and advances
research aggressively and systematically in terms of both finances andresearch space. In order to more vigorously advance general research projects thathave been established, “KLL Research Space” is loaned on a fee-paid basis. Thereis usable space in the Sousoukan of the Yagami Campus (a total of 2,519m2
available; see page 34), as well as on the Shin-Kawasaki Town Campus.
Furthermore, researchers from corporations and elsewhere outside of the university who participate in research are granted the status of “Researcher ofKLL.” They are able to perform research activities smoothly at Keio by, forexample, utilizing the Information and Media Center for Science andTechnology (library).

Returning of Research Achievements to Society
Annually in December, the KLL holds the Keio Techno-Mall, an exhibition
aimed at corporate managers. The exhibition introduces research achievements
and explores ways to generate new businesses. In 2004, there were 67 booths
introducing research achievements and over 1,500 attendees. (The Keio
Techno-Mall 2005 is scheduled for 2 December 2005 at the Tokyo International
Forum in Yurakucho.) In cooperation with the Intellectual Property Center, the event
supports the patenting and commercialization of research achievements andfulfills the cycle of intellectual creation by returning the achievements to society.

50

0
2000
Governmentorganizations /Public-service
corporations

2001

2002

2003

2004
Private corporations(commissioned
research, etc.)

Private corporations(specified
contributions)

Commissioned Research Projects (excerpt)

For Inquiries:“Training Program for System
Biologists in Keio University”
Ministry of Education, Culture, Sports,
Science and Technology (MEXT)
Professor Kotaro Oka
Fundamental Science and Technology“Development of New Tools for in vitro
Analysis of Protein-Protein Interactions
Constructing Networks in vivo”
MEXT
Professor Hiroshi Yanagawa
Fundamental Science and Technology“Target Gene Exploration for Drug
Discovery”
New Energy and Industrial Technology
Development Organization (NEDO)
Professor Hiroshi Yanagawa
Fundamental Science and Technology

Secretariat of the KLL(c/o Office of Research Administration,
Yagami Campus)
TEL: +81-45-566-1470
E-mail: staff@kll.keio.ac.jp
http://www.kll.keio.ac.jp/“A Study on Fundamental Technology
of Distributed Real-time Network for
Human Activity”
MEXT
Professor Yuichiro Anzai
Science for Open and Environmental
Systems“Highly Dependable Software for
Capturing Environmental Information”
MEXT
Professor Shinji Ozawa
Science for Open and Environmental
Systems“Basic and Leading-edge Research
on AHS Technology and Evaluation
Methodology for Introduction of ITS”
National Institute for Land andInfrastructure Management
Professor Hironao Kawashima
Science for Open and Environmental
Systems

KLL Liaison Office
TEL: +81-45-566-1438
E-mail: liaison@educ.cc.keio.ac.jp
http://www.kll.keio.ac.jp/liaison/index.html

KEIO U-honbun̲E 05.11.29 7:35 PM ページ 11

Research Centers
Shinanomachi Research Park

Shinanomachi Campus
Center for Translational Research: From Bench to Bed

The Research Park provides 55 laboratory spaces called units for joint research projects between industry, government,
and academia. Durations of the research projects vary from three to five years.

Schematic of Research Park for Participants

Project Leader

Research Plan Adopted

Duration of the ProjectEvaluation

A project leader applicant to the
Research Park may be either a faculty
member affiliated with the Keio
University School of Medicine or a
researcher of another university,
research institution, or corporation,
but a faculty member of Keioshould be included as a responsible
official in the project team in
the case that the leader is fromoutside Keio.

Final decision for acceptance to
the Research Park made by the
Evaluation Committee.

Contract limited to three to five years.

The Evaluation Committee evaluates
each project at the end of the second
year and upon completion of theresearch in the final year.

Schematic Diagram

Shinanomachi Campus
11

Faculty of Scienceand Technology

Center for Integrated Medical Research
Research Park

School of Medicine

Research Plan

Keio University Hospital

Faculty of Environmental
Information, etc.

Organizational Chart

Research Support
Department

Graduate School of Medicine

Submit research plan application
upon opportunities announcement.

Implementation of the
Research

Acquisition and Managementof Intellectual Property

The project leader or corporations
sign a joint research contract with
Keio University.

All costs related to the research
project from moving in to removal
upon completion—for facilities,
equipment, plumbing work, utilities, and general administration
costs and expenses—are born by
the project leader.

The Intellectual Property Center (IPC) at
Keio University offers advisory services
to researchers regarding acquisitionof intellectual property rights andtechnology transfer.

Central Research Laboratory

Projects at the Research Park available at:Laboratory Animals Center

School of Medicine

Research Implementation
Contract

Center for Integrated Medical Research (CIMR)

http://www.rpk.med.keio.ac.jp/project/project_e.htm

Research field of Faculty of School of Medicine available at:
http://www.cimr.med.keio.ac.jp/ichiran_e.htm

RI Center
Board of CIMR
Evaluation Committee of CIMR

Strategic Research
Department

High-tech Research Center
Research Park

Privately Funded Research Projects• Joint Research with Corporations
Joint Research Projects

Major Research Projects
Publicly Funded Projects
Ministry of Education, Culture, Sports,
Science and Technology (MEXT)• 21st Century Revolutionary Leadingedge Life Science Technology
Development ProjectTranslational Research Programs“Development of Immunotherapy by
Intratumoral Administration of Dendritic Cells”
Professor Yutaka Kawakami, Institute forAdvanced Medical Research• Special Assistance for Promoting theAdvancement of the Education andResearch of the Private University
Academic Frontier Promotion Project
Application of High Throughput
Metabolome Technology to Biomedical
Sciences• Leading ProjectHigh Technology Research Center Project
Project of the Research and Development
Center for the Regenerative Medicine andTherapeutics, Keio University School of
Medicine

Leading Project for Biosimulation“Development and Application ofComputer-based Biosimulation Assisted by
Metabolome Analyses”
Professor Makoto Suematsu, BiochemistrySocial-Academia Partnership Research
Promotion Project
Development of Diagnostic andTherapeutic Techniques for the Central
Nervous System Diseases

Leading Project of the Regenerative
Medicine“Development of Stem Cell Therapy for
Spinal Cord Injuries”
Professor Hideyuki Okano, Physiology• Grants-in-Aid for Scientific
Research (Kakenhi)
Specially Promoted Research“Regulation of Hematopoietic Stem Cell
Division in a Niche”
Professor Toshio Suda, Cell Differentiation

Creative Scientific Research“Activation of Stem Cells and
Neurogenesis in Adult Brains: Their
Regulatory Mechanism and Visualization”
Professor Hideyuki Okano, Physiology“Biomedical Application of Gas Biology
through Multidisciplinary Approaches”
Professor Makoto Suematsu, Biochemistry
Japan Science and Technology Agency(JST)“Studies on the Development andRegeneration of Central Nervous System
Based on the Stem Cell System”
Professor Hideyuki Okano, Physiology“Training Course for Technical Assistants
on in vivo Medical Science”
Professor Sadakazu Aiso, Anatomy“Neuronal Death-oriented Development of
Therapy against Alzheimer’s Disease”
Professor Masaaki Matsuoka,
Pharmacology

NEDO“Clinical Extension of Technologies for
Gas-mediated Manipulation ofMacromolecular Functions”
Professor Makoto Suematsu, Biochemistry“Establishment of Regenerative Therapy
Using Peripheral Blood Monocytes”
Assistant Professor Masataka Kuwana,
Institute for Advanced Medical Research
National Institute of Biomedical
Innovation (NiBio)“Development of the Regenerative
Cardiomyocytes from Human and Simian
Embryonic Stem Cells”
Professor Keiichi Fukuda, Regenerative
Medicine

Hamano Life Science Research Foundation“Imaging of Higher Order Brain Function”
Pfizer Japan, Inc.
Nipro
“Development of New
Therapies for Inflammatory Bowel Disease
Using Regeneration Technique of Mucosal
Epithelium”
Institute of Medicinal Molecular Design,
Inc. (IMMD)“Development of Novel Drugs Based on
Rational Drug Design Methods”
Mitsubishi Pharma Corporation“Development of Platelet Substitutes”
Mitsubishi Pharma Corporation“Establishment of Human Monoclonal
Antibody”
Daiichi Pharmaceutical Co.
Kirin Brewery Co.
“Identification of Tumor Antigens Useful for
Prevention, Diagnosis, and Treatment of
Gastroenterological Cancer”

Monthly Friday Seminar Series atCenter for Integrated Medical Research
Kowa Company, Ltd.
“Elucidation of Mechanism and Investigationof Treatment for Sjögren Syndrome”
Toshiba Corporation“Non-invasive Radiology System for the
Diagnosis and Therapy of Cancer”
Chugai Pharmaceutical Co., Ltd.
“Development of Novel Therapy for
Hematological Malignancies”
Daiichi Suntory Pharma Co., Ltd.
“Development of the Method Generating
Cardiomyocytes from ES Cells andEstablishment of Regenerative Therapeutic
Technology for Heart Failure”
Astellas Pharma Inc.
“Vascular Medicine Project”
GE Yokogawa Medical Systems Ltd.
“Development of Novel Systematic Diagnosis
with MDCT and MRI in Cardiovascular
System”
Roche Diagnostics K.K.
“Development of a Quantitative Real-time
Diagnosis for Micrometastasis Based on the
Sentinel Node Concept”

For Inquiries:
Office of Research Administration at Shinanomachi
Tel: +81-3-5363-3879
E-mail: ras-shinanomachi@adst.keio.ac.jp
http://www.med.keio.ac.jp/research/

Medical & Biological Laboratories Co., Ltd.
Hitachi, Ltd.
Noevir Co., Ltd.
Canon Inc.
“Development of DNA Chip and its
Application”
Takeda Pharmaceutical Company
Limited“KT-neural Regeneration Project”• Commissioned and Joint
Researches• Endowed Laboratory
Oriental Medicine
Advanced Cardiac Therapeutics
Growth and Development Research
Bridgestone Laboratory of Developmental
and Regenerative Neurobiology
Uniden Musculoskeletal Reconstruction
and Regeneration Surgery

Center for Integrated Medical Research
http://www.cimr.med.keio.ac.jp/index_e.htm
Shinanomachi Research Park
http://www.rpk.med.keio.ac.jp/index_e.htm

Seminars to Date (excerpts)
19th Seminar: Yoshinori Fujiyoshi, Ph.D.
Kyoto University“Structural and Functional Study of Water
and Ion Channels as a Stage Struggling toUnderstand Nervous System”
23rd Seminar: Stefan Karlsson, Ph.D.
Lund University Hospital“The Role of Smad Signaling in
Hematopoietic Cells”
24th Seminar: Hachiro Sugimoto, Ph.D.
Kyoto University“Chasing a Dream of Discovering AntiAlzheimer’s Disease Drugs”
26th Seminar: Urban Lendahl, Ph.D.
Karolinska Institute“Notch Signaling During Development andDisease”
27th Seminar: Katsuhiko Mikoshiba, Ph.D.
The University of Tokyo“Intracellular Ca2+ Dynamics and Cell
Function: Its Physiology and Pathogenesis”
32nd Seminar: Toshiaki Noce, Ph.D.
Mitsubishi Kagaku Institute of Life Sciences“Topics in the Relationship between Germ
Cell Research and Regenerative Medicine”

Research Centers—Shinanomachi Campus

Keio University Annual Report on Research Activities 2004–2005

Graduate School of
Medicine

12

KEIO U-honbun̲E 05.11.29 7:36 PM ページ 13

Research Centers

Shonan Fujisawa Campus (SFC)
Contributing to Social Development with Cutting-edge
Research Based on Interdisciplinary Cooperation

SFC
13

The Keio Research Institute at SFC is an affiliate of
the three faculties and Graduate School of Media andGovernance which promotes research activities at SFC.
As a leading center of cutting-edge research in the
21st century, the Institute works to further enhance society’s advancement by performing ground-breaking researchbased on interdisciplinary cooperation and by nurturing a
two-way partnership between educational and research
activities at the campus. This includes all related activities
with industry, government, and academia both in Japanand overseas. Specific measures to achieve this include
promoting joint research projects with other organizations andsupporting venture incubation efforts. One of the uniqueaspects of the Keio Research Institute at SFC is its SFC
Research Consortium, which encourages university-led
collaborative research by multiple organizations. There are
currently 14 such projects underway (as of July 2005).
Additionally, the Institute was commissioned with
230 funded research projects amounting to approximately ¥2.2
billion from government agencies, local governments, and private companies in FY2004.
Researchers for these projects come not only fromwithin SFC, but outside as well—approximately 300 visiting
researchers conduct research at the Institute. The Institute iscommitted to presenting its research achievements widely tothe public so that the results of its efforts flow back tosociety.
http://www.kri.sfc.keio.ac.jp/english/index.html
Number of researchers: (as of 6 July 2005)
Full-time staff: 180
Researchers appointed with external funding: 94
Visiting Researchers: 329
Total: 603

Contract/Joint Research
SFC ResearchConsortium

Venture Incubation
AssistanceLaboratory

Laboratory

SFC Research Consortium

The Keio Research Institute at SFC is proud of
having laboratory system which enables SFC’s
researchers to form research groups of those
who have different academic backgrounds yet
share the same research interests and objectives. These groups carry out interdisciplinary
collaborative research projects.
Currently, the following 12 laboratories are in
operation:■ Career Resource Laboratory■ Internet Research Laboratory■ Geo-informatics Laboratory■ Digital Cinema Laboratory■ Bioinformatics Laboratory■ Auto-ID Laboratory■ Ubiquitous Computing & Communication
Laboratory■ ID Business and Social Model ResearchLaboratory■ Healthcare Informatics Research Laboratory■ Keitai Laboratory■ SIV Entrepreneur Laboratory■ Interaction Design Laboratory
http://www.kri.sfc.keio.ac.jp/
english/laboratory/laboratory.html

SFC Research consortium conducts joint research
projects which tackle large issues under the premise of
mutual benefit. The university takes the initiative indeciding a research topic and invites participation frommultiple external organizations including businesses andgovernment, to extend efforts beyond a single field ofstudy.

Keio ResearchInstitute at SFC

Currently, the following 14 consortium projects
have been organized:■ Building Conceptual Media and Application Systems■ VCOM■ Research on Advanced Next-generation
Internet Architecture■ Building Advanced Information Infrastructures■ VSI (Virtual Systems Institute)■ Sharing Human Intellect Project■ Research Project on Urban Computerization andPublic Space■ E-CELL Consortium■ DVTS (Digital Video Transport System) Consortium■ SFC “Design Museum Factory” Consortium■ DMNET (Digital Media Learning Network)■ e-Care Consortium■ SIV Entrepreneur Education Research Consortium■ Interaction Design Research Consortium
http://www.kri.sfc.keio.ac.jp/
english/research/consortium.html

Case Studies
Keitai Laboratory
Given the interrelated nature of technologicalchanges in mobile communications and social transformations, it is of utmost importance to establish a mutually
beneficial relationship between the two by focusing on
interdisciplinary, composite research.
The Keitai (mobile phone) Laboratory researches thesocial and cultural impact of the mobile phone from a wide
range of perspectives and approaches and attempts todescribe the nature of a “ubiquitous society.” Cutting
across graduate programs, it provides for academic guidance as well as group studies and research.
http://www.kri.sfc.keio.ac.jp/english/laboratory/Keitai.html
Building Digital Asia Utilizing GIS Technology
The Digital Asia project is a dynamic, five-year joint project between domestic and overseas research institutions.
This project takes an integrated approach to examine afuture strategy for the Asian region based on environmental,
risk management, and information technology (adopted in
FY2004 as a Ministry of Education, Culture, Sports,
Science and Technology (MEXT) “Academic Frontier”
Project ; “Fusion Research for Conceptualizing Regional
Strategy through Construction and Operation of Digital
Asia”).
e-Care Project
The e-Care project consists of integrated research on
the creation and applications of an e-Care social model
which applies information communications technology tothe health care field. By applying advanced infrastructuretechnology from the fields of nursing, medical care engineering, and information communications, it seeks to build a
new social system which can respond to today’s declining
birth rate and aging population (adopted in FY2005 as a
MEXT “High-tech Research Center” Project entitled“Fusion Research for formulation of an e-Care Model
Social System and its Applications based on Information
Communications Technology”).

Venture Incubation

Returning Research Achievements to Society

Making Research Achievements
Available to the Public
SFC Open Research ForumThe Keio Research Institute at SFC believes returning
research achievements to society to be an important social
duty. In order to make achievements widely available tothe public, the Institute annually organizes an SFC Open
Research Forum where various research projects at theInstitute are disclosed to industry, national and local
government agencies, and academic society. The current
status and future plans of projects are made public at theForum through exhibitions, demonstrations, and symposiums.
Furthermore, the Institute holds panel discussions between
industrial and political experts and formulates proposals
based on the discussions which it offers to society. These
efforts aim to strengthen cooperation between industry,
government, and academia and incorporate external feedback
into the planning of future research projects.
http://orf. sfc.keio.ac.jp

SFC Forum

Keio SFC—DNP Seminar

The SFC Forum provides a setting where businessleaders and university staff can engage in discussions thatgenerate and reevaluate the knowledge required by thecurrent age. Its purpose is to give people living in today’s dramatically changing society a forum at the university—aplace where they can share a wealth of ideas and broad
perspectives in order to anticipate issues and build a vision for
the future. Specifically, on a monthly basis the Forum holds
luncheons and research seminars at which innovative SFC
research is introduced, management seminars with memberled discussions, etc. Additionally, it offers Research
Conferences for joint and commissioned projects in the
pre-launch stage so that members can exchange ideas
with SFC researchers in their field of interest.
http://www.sfc.keio.ac.jp/sfc-forum/

The Keio SFC—DNP Seminar is a collaborative project with Dai Nippon Printing Co., Ltd. (DNP) that was organized through a Research Conference offered at the SFC
Forum. From the view points of social assumptions andtechnology, the Seminar seeks the future vision towardrealization of “the emergent society” produced by changes indiversification of information communications.

Keio University is expanding incubation facilities(Keio Fujisawa Innovation Village) for entrepreneurs in joint
cooperation with the Organization for Small & Medium
Enterprises and Regional Innovation (SMRJ), Kanagawa
Prefecture and Fujisawa City.
These facilities will be offered for rent at reasonablerates to entrepreneurs who utilize SFC knowledge andinformation in fields such as IT, biotechnology, environmentconscious technology, nursing and health care, healthmanagement, city design, and social system design, anddesire to begin a start-up business in alliance with Keio.
Applications to rent the facilities have started in fall 2005,
with a screening done to decide allocations (entrepreneurs
who wish to utilize knowledge from and ally themselveswith other campuses may also apply).
Keio University hopes that a variety of new businesses will emerge from these facilities, including listedcompanies active at the global level and community-basedsocial ventures.
At the facilities, a number of incubation managers
will be present to assist the businesses through advice andmatching suited to their needs.

For Inquiries and Document Requests:
Office of Research Administration,
Shonan Fujisawa Campus
Tel: +81-466-49-3436
Fax: +81-466-49-3594

E-mail addresses:
Participation in research activities: sec-kri@sfc.keio.ac.jp
Press related: press-kri@sfc.keio.ac.jp
General inquiries: info-kri@sfc.keio.ac.jp
Keio Research Institute at SFC website:
http://www.kri.sfc.keio.ac.jp/english/index.html

14
Research Centers—Shonan Fujisawa Campus (SFC)

Keio University Annual Report on Research Activities 2004–2005

Keio University’s fifth campus, SFC, was built in 1990 asa site for research and education based on completely new
concepts adapted to the changing times. It includes thethree faculties of Policy Management, Environmental
Information, and Nursing and Medical Care as well as the
Graduate School of Media and Governance which opened in
1994. SFC masters programs aim at nurturing “high-quality
professionals” who are able to respond to society’s diverse
needs with expertise and practical experience in identifying
and solving problems. Its doctoral program cultivates “topquality researchers, educators, and specialists” with expert
professionalism, precise decision-making capabilities, andabundant creativity. As its daily mission, the SFC strives tocontribute back to society by producing graduates who will
flourish as next generation professionals and conduct cuttingedge research. In order to respond to the complex anddiverse needs of today’s society, SFC also opened the
Graduate School of Health Management in April 2005. Thisschool further expands and enhances the concept of theFaculty of Nursing and Medical Care by providing a program which enables graduates of the sciences and humanities alike to grapple with the broad theme of “health.”
Situated on a futuristic 330,000 square meter campus, SFC seeks to maintain a balance between the latest technology and a rich, natural environment. Research projects
serve as the core of a participatory curriculum which
instills students with specialized knowledge and practicalskills.
http://www.sfc.keio.ac.jp/index.html.en

Keio Research Institute at SFC

World-Leading Fusion Research Technology

KEIO U-honbun̲E 05.11.29 7:36 PM ページ 15

Research Centers
Open Campus

Shin-Kawasaki Town Campus

On Saturday, 2 October 2004, the Open Campus began with greetings from the President of Keio University and the Mayor of Kawasaki City, and was attended by many residents, students,
and individuals from businesses, among others.

Open and Cutting-edge Research Facility Pursuing
Industry-Government-Academia Collaboration

FY2004 Saturdays Seminars

Keio University Annual Report on Research Activities 2004–2005

cutting-edge joint research among industry, government, and academia through collaboration and cooperation with the Kawasaki City. K2 (“KSquare”) represents the double meaning of (1) Keio (one “K”) and Kawasaki (another “K”) teaming up and thereby producing a squared effect by joining forces, and (2) the campus square (plaza). This is where the Shin-Kawasaki Frontier Research and Education Collaborative Square were established
as a frontier research organization within Keio University.
This roughly two-hectare site surrounded by greenery houses four two-story research buildings and one welfare building where a total of
approximately 370 researchers including graduate students, joint researchers, and others work day and night to advance research.
At present, 14 representative Keio University frontier research projects that are rooted in industry-government-academia collaboration arebeing conducted here. In addition to using frontier research to enhance the technologies of local businesses and cultivate local industry through thegeneration of new industries, the K2 Town Campus also holds open seminars (eight seminars were held in FY2004), open campus days, and other events
that serve to make city residents and young people aware of numerous types of learning centered on science and technology.

Toward Industry-GovernmentAcademia Collaboration
The Shin-Kawasaki Frontier Research and Education
Collaborative Square (K-FRECS) is a center which aims for not
only industry-government-academia collaboration, but alsocollaboration with the local community. It leads to vitalization of
the local community by transmitting its research achievements to the world at large, as well as cultivating new industries
and contributing the human resources to support them.
Moreover, Keio University is also participating in theestablishment of the Kawasaki Innovation Liaison Council forthe purpose of building a network for industry-governmentacademia collaboration, advancing innovation within thecommunity, and supporting the founding of new business andfostering of entrepreneurs.
The K2 Town Campus will continue to work as a centerfor collaboration that is meaningful to both Keio and the
Kawasaki City.

370 Registered Researchers

Open Seminars

Collaboration
Contribution towithSociety
the Kawasaki City and the Community

Striving for Industry-Government-Academia
Collaboration
The K2 Town Campus■ Contributing to Society through Frontier Research
The campus functions as a center for industrygovernment-academia collaboration by using intellectual
property and research on cutting-edge technology in order toenhance technologies for local businesses, as well as to create
and foster new industries.
■ Contributing to Society through Science Education
and Awareness Campaigns
Under the cooperation of each frontier research project,various seminars are held in order to inform residents andyoung people of the numerous types of learning centered on
science and technology.

Research Projects * Completed in FY2004 ** New Project starting in FY2005
K-Building

Real-time Network Project
Yuichiro Anzai (Professor, Faculty of Science and Technology)*

K-Building

Distributed Real-time Processing Project—Distributed Real-time
Information Processing for Humanoids
Nobuyuki Yamasaki (Associate Professor, Faculty of Science and Technology)

K-Building
K-Building

K-Building

Project on Flexible Network for Hard-real-time and Hard-real-world System
Kouhei Ohnishi (Professor, Faculty of Science and Technology)
Experimental Research Project on Autonomous, Distributed, Cooperative
Control by Space and Outdoor Robots
Yoshiaki Ookami (Professor, Faculty of Science and Technology)*/Kazuo Yoshida (Professor, Faculty of Science and Technology)**Technology of Air Cleaning for Creating the Comforts of Life
Shigeru Tanaka (Professor, Faculty of Science and Technology)

K-Building

Research Project for Understanding and Analysis of Multiple Camera
Hideo Saito (Associate Professor, Faculty of Science and Technology)*

K-Building

Next Generation Broadband Mobile Communication Research Project
Masao Nakagawa (Professor, Faculty of Science and Technology)

K-Building

VISOR Project—Flexible Communication Systems
Shinichiro Haruyama (Visiting Professor, Faculty of Science and Technology)

K-Building

Genome-based Drug Discovery Project
Masaya Imoto (Professor, Faculty of Science and Technology)**

K-Building

NEDO Device Development Project for Next Generation Robot Motion Control
Research and Development of System LSI (M-RMTP) for Next Generation Robots
Nobuyuki Yamasaki (Associate Professor, Faculty of Science and Technology)**

E-Building

ERATO Koike Photonics Polymer Project—“Fiber to the Display” by
High-speed Data Transmission and High-quality Displays
Yasuhiro Koike (Professor, Faculty of Science and Technology)

I -Building

Beyond the Human Genome Project DNA Science: Basic Research,
Medical Applications and Public Campaign
Nobuyoshi Shimizu (Professor, School of Medicine)

O-Building

O-Building

Instructor

Towards the Innovation of Space Activities by Cooperating Robots—The 21st Century COE Program: Paradigm Shift from Intelligence to Life—

Yoshiaki Ookami(Professor, K-Building Project)

02/10/04
Open Seminar

What is Distributed Real-time Processing?
—We Can Meet the Deadline!—

Nobuyuki Yamasaki(Assistant Professor, K-Building Project)

23/10/04
Open Seminar

Computer Graphics—Paintings Seen by Computer and Drawn by Computer—

Yoshio Ohno
(Professor, Faculty of Science and Technology)

04/12/04
Extension Lecture

Human Factors Engineering of the Future—Toward Harmonization between Human and Machines for Safety, Security and Amenities in Society—

Yusaku Okada (Associate Professor, Faculty of
Science and Technology)

11/12/04
Extension Lecture

Human-friendly, Environmentally friendly Buildings—Architecture with System Life—

Shuzo Murakami(Professor, Faculty of Science and Technology)

18/12/04
Open Seminar

The Evolutionary Transportation Systems: ITS

Hironao Kawashima(Professor, Faculty of Science and Technology)

15/01/05
Open Seminar

Genome School for the Young

Nobuyoshi Shimizu(Professor, I-Building Project)

29/01/05
Open Seminar

The Forefront of Rehabilitation Engineering—Interface between Medicine and Engineering—

Yutaka Tomita(Professor, Faculty of Science and Technology)

The Open Campus 2005 was held on Saturday, 12 November 2005

■ Frontier Research Projects
14 frontier research projects rooted in industrygovernment-academia collaboration are being carried out
across faculties and research courses, with a staff of over 370
researchers (including full-time teachers, joint researchers, andgraduate students) working day and night to advance research.

Frontier Research

Establishment and Fostering of
New Industries

Topic

02/10/04
Open Seminar

Future Vehicle Project—Vehicles on the Ground Using the Technology
of Drive and Automatic Driving
Hiroshi Shimizu (Professor, Faculty of Environmental Information)
Next Generation Nano-technology Thin Film Project(Wide Applications of Wet-Process Nano Coating)
Seimei Shiratori (Associate Professor, Faculty of Science and Technology)

O-Building

Project for IP-based Wireless Communication Technologies—For a
Combination of Cellular and Ad-hoc Networks
Masao Nakagawa (Professor, Faculty of Science and Technology)

O-Building

The WIDE Project—Research on IPv6
Jun Murai (Professor, Faculty of Environmental Information)

Various seminars related to numerous different types of learning centered on science and technology are organized to enlighten residents, young people, and individuals from the business world. In FY2004,
a total of eight open seminars and open lectures were held that were attended by many participants. Additionally, numerous seminars are also planned for FY2005.

The K2 Corner Starts at Kawasaki FM
From January 2005, the Shin-Kawasaki Town Campus (K2 Town Campus) has been presented on radio by Kawasaki FM 79.1.
On the third Tuesday of each month, from 13:10-13:40, a researcher of the K2 Town Campus appears at the studio and introduces frontier research that is currently being advanced.
Month

Instructor

January

Professor Yasuhiro Koike

Content
Plastic Optical Fiber and Broadband Society

February

Professor Masao Nakagawa

Progress in Mobile Phones and Visible Optical Communication

March

Professor Hiroshi Shimizu

Vehicles in the Near Future

April

Professor Kouhei Ohnishi

Evolving Robot: From Grasping to TouchingMay

Associate Professor Seimei Shiratori

Nano Technology Changes Our Life

June

Professor Nobuyoshi Shimizu

The Forefront of Genome Research

July

Professor Shigeru Tanaka

Simple and Convenient Scrubber can Eliminate Indoor Contaminants

Railroad Map

For Inquiries:

Shibuya
HiyoshiHiyoshi Campus

ShinKawasaki

Tokyo (20 min.)

Yagami Campus
K2 Town Campus

Shinagawa (12 min.)Kashimada

Kawasaki (7 min.)Yokohama (9 min.)Tokyu Toyoko Line
JR Yokosuka Line
JR Nambu Line
JR Tokaido Line
JR Yamanote Line

Shin-Kawasaki Town Campus
Shin-Kawasaki Keio Frontier Research and Education
Collaborative Square (K-FRECS)
144-8 Ogura, Saiwai-ku, Kawasaki-shi, Kanagawa,Japan 212-0054
Tel: +81-44-580-1580
Fax: +81-44-580-1570
E-mail: k2-tc@adst.keio.ac.jp
http://www.k2.keio.ac.jp/
Access by train
10-minute walk from Shin-Kawasaki Station, JR Yokosuka Line
15-minute walk from Kashimada Station, JR Nambu Line16
Research Centers—Shin-Kawasaki Town Campus

15

The Shin-Kawasaki Town Campus, popularly known as the K2 Town Campus, was established in the spring of 2000 as a facility responsible for

DD/MM/YYKEIO U-honbun̲E 05.11.29 7:36 PM ページ 17

Research Centers

Tsuruoka Town Campus
This is not just a research institute.
This is a scientific adventure.

EventsCommercialization• Introduction to Bioscience for Tsuruoka Citizens
The introductory bioscience course for general public and taught by researchers of the
IAB. There were 119 participants in FY2004.

A Bio-venture Company from Keio University
Human Metabolome Technologies, Inc. (HMT)
http://www.humanmetabolome.com/• Summer Bio College
This is a basic hands-on program in biotechnology aimed at high school students in
Tsuruoka City, Yamagata Prefecture, and those in the Keio’s affiliated high schools. There were
20 participants in FY2004.

Human Metabolome Technologies, Inc. (HMT) is a venture company established inJuly 2003 by Professor Masaru Tomita, Associate Professor Tomoyoshi Soga, and others fromthe IAB, based on the IAB’s measurement and analysis technology for metabolomes. HMT
conducts R&D at the IAB aimed at industrial applications in medical care, drug discovery, foodfermentation, etc. In October 2003, HMT became the first company to be invested by the
Entrepreneur Assistance Fund of Keio University. The company began joint research with Mizkan
Group Co. Ltd. in January 2004, Ajinomoto Co., Inc. in June 2004, and Mitsubishi Pharma
Corporation in February 2005.

• Keio Summer Bio CampThis is a basic hands-on program in biotechnology for any high school students from all overJapan, in which 19 students participated.

17

In April 2001, Keio University established the Tsuruoka Town Campus of Keio (TTCK) in
Tsuruoka City, Yamagata Prefecture, with the cooperation of Yamagata Prefecture and themunicipalities of the Shonai region. The cornerstone of the campus is the Institute for Advanced
Biosciences (IAB).
Research at IAB is performed at two facilities: the Center Building and the Bio-lab.
TTCK conducts, closely and jointly working with the other campuses of Keio, research anddevelopment in advanced areas and enhances research and educational activities. It proactivelytransfers newly created technologies to local governments and businesses to encourage industrygovernment-academia collaboration, for contributing to regional development as well as to theadvancement of science and technology in Japan.

18
Research Centers—Tsuruoka Town Campus

Keio University Annual Report on Research Activities 2004–2005• The Advanced Biosciences Seminar with Experiments
This seminar is offered for teachers at elementary, junior high, and high schools in
Tsuruoka City, who are either science teachers or those interested in biosciences. The
seminar utilizes the research equipment of the IAB‘s Bio-lab and literature at the Chido Library,specializing in areas of natural sciences centered on bioscience. There were 17 participants
in FY2004.

Bio-labHigh-throughput and quantitive CE-MS methods which can measure thousands ofcharged metabolites

Institute for Advanced Biosciences (IAB)The Institute for Advanced Biosciences (IAB) is a full-fledged laboratory for bioresearch set up at the TTCK in April 2001. The IAB, using theleading-edge biotechnology, cyclopaedically measures and analyzes the cellular activities of organisms and microbes, simulates various cell functions
and activities by computer, and applies its findings to areas such as medical care and food fermentation.
The IAB attracts attention of the world as a pioneer of “integrated systems biology,” a new IT-driven bioscience.
http://www.iab.keio.ac.jp/index.html.en

Major Research Projects
MEXT Leading Project for Biosimulation“Development and Application ofComputer-based Biosimulation Assisted by
Metabolome Analyses”(2003-2007)
MEXT 21st Century COE Program“Understanding and Control of Life’s
Function via Systems Biology”(2002-2006)

Other Related Facilities
Tsuruoka Metabolome Campus is a research facility of Tsuruoka City aimed at cluster formation of bioresearch and development, with the IAB as
the cornerstone. HMT began business in 2005. From mid-2006, RIKEN is also expected to open a new institute and joint research with the IAB will startin earnest.

Facility for Incubation and Industry-Academia Joint Research (tentative name)
METI, Human Resource Development
Programs in Bioindustry“Fostering of Integrated Systems Biologists”(2004)
National Institute of Agrobiological
Sciences (NIAS), Program for Rice
Genome Research (PRGR)“Development of the Rice Genome
Simulators—Development of Efficient
Analysis Systems for Rice Genome
Transcription Control Networks”(2002-2004)

Research System
Major Joint Research Organizations
The Faculty of Science and Technology, the School of Medicine, Shonan Fujisawa
Campus, RIKEN, and Human Metabolome Technologies, Inc.

Educational Activities
The IAB develops and deploys educational activities for students with different majors inundergraduate or graduate school of Keio University, under the ideal that advanced
research and education should be inseparable. In FY2004, 30 students in the spring semesterand 35 students in the fall semester participated in the programs and activities offered at TTCK.

New Energy and Industrial Technology
Development Organization (NEDO)“Development of a Technological
Infrastructure for Production Processes
Using Biological Functions—Developmentof Cellar Modeling Technology”(2001-2005)

Ministry of Health, Labour and Welfare(MHLW), Grant-in-Aid for Cancer
Research“Research on Development of New
Medical Treatment Based on Cancer
Biology”(2005)

Yamagata Prefecture and Tsuruoka
City“Computer Aided Design of UsefulMicrobes”(2001-2005)• Bio CampThe Bio Camp is a program for students of the Shonan Fujisawa Campus (SFC) at Keio tospend one semester at the TTCK and experience the basics of biotechnology. The program
begins with an introduction to the handling of laboratory instruments because the students haveno experience with experiments. Each student extracts his/her own DNA and analyzes thegene for alcohol-degrading enzymes, and self-diagnoses through genetic testing whether his/herlevel of tolerance for alcohol is high or low. At the end, the students decode the genome
sequences through state-of-the-art DNA sequencers.
• Bioinformatics Program
The Bioinformatics Program is a rare graduate program in the world in the sensethat students can earn credits from both the SFC (bioinformatics) and the TTCK’s IAB (systems
biology). At the TTCK, a number of experiments and laboratory trainings are provided, such as“genome sequencing,” “metabolome analysis,” and “proteome analysis,” using mostadvanced DNA sequencers, mass spectrometers, etc.

Main coordinating body: Tsuruoka City
Location: 245 Mizukami Kakuganji, Oaza, Tsuruoka-shi, etc.
Site area: Approx. 1.5ha
Building structure: Two-floors, steel-framed
Building scale: Total floor area approx. 3,700m2
Research unit specs• Rooms for rent:
29 units; 1 unit = 7m x 10m (approx. 75m2)
Ceiling height: Approx. 2.8m
• Room specs
Floors: Free-access floors(Floor weight capacity: 500kg/m2)

Groundwork: Chemical-resistant polyvinyl sheet finish
Equipments provided: Electricity (single phase 100V/200V,
3-phase 200V), water supply and drainage, city gas (13A)
Security: 24-hr. access with IC card
• Common-Use Building: Meeting room, lounge, etc.
Monthly rent: (A-Building) 89,000-92,000 yen(No deposit or guarantee money. Utilities born by tenants.)
Starting date for operation: All services will start on 1
June 2006, but 3 units in A-Building have been rented to
HMT since 1 May 2005, and 6 units in B-Building will be Rendering of Facility for Incubation and Industry-Academia Joint
Research (tentative name)available from 1 April 2006.
Duration of tenancy: within five years

Major Awards

For Inquiries:

November 2001
“Yamagata Keizai Doyukai (Association of Corporate
Executives) Grand Prize, Yamagata Landscape DesignAward”

June 2004“Industry-Academia-Government Collaborative DistinguishedService Commendation (Award of the Minister of State for
Science and Technology Policy)”

June 2003“Nihon Kogyo Shimbunsha Award in the 17th Dokusousei
wo Kirihiraku Sentan Gijutu Taishou (Leading-edge
Technology for Originality and Creativity)”

April 2005
“First Prize in the 5th Japan Biotechnology Business
Competition”

November 2003
“IBM Shared University Research Award”

Tsuruoka Town Campus
Keio Frontier Research and Education Collaborative
Square (K-FRECS) at Tsuruoka
14-1 Baba-cho, Tsuruoka-shi, Yamagata, Japan 997-0035
Tel: +81-235-29-0800 (main)
Fax: +81-235-29-0809
E-mail: office@ttck.keio.ac.jp
http://www.ttck.keio.ac.jp/

KEIO U-honbun̲E 05.11.29 7:36 PM ページ 19

Research Centers

Nowton Court Keio University
An International Center for Transmission of Knowledge

19

Vice-Director, Advanced Research Section

Hideyuki Tokuda

Professor, Faculty of Environmental Information, Graduate School of Media and GovernanceVice-Director, Context Integration, System Research & Development Section

Yasushi Kiyoki

Professor, Faculty of Environmental InformationVice-Director, International Collaboration Section

Masahiro Kuroda

Professor, Faculty of Business and CommerceVice-Director, Production Section

Yutaka Ohga

The DMC

Content Design Application Research Unit Leader

Yoichi Sumi

Professor, Faculty of Letterse-Learning Unit Leader

Shinya Sugiyama

Professor, Faculty of Economics

Advanced Media Technology Unit Leader

Hiroaki Chiyokura

Professor, Faculty of Environmental Information

Advanced Content Technology Unit Leader

Shinji Ozawa

Professor, Faculty of Science and Technology

Networks and Security System Unit Leader

Sadayasu Ono

Professor, Graduate School of Media and GovernanceNaoki Koizumi

Professor, Keio Law School

International Intellectual Property and Standardization Strategy Unit Leader
Organization (as of March 31, 2004): Researchers…20

On 9-10 March 2005, the “Keio Workshop on International Collaboration in Digital Media and Content” was held as a workshop of the ResearchInstitute for Digital Media and Content (DMC) (see below) launched in July 2004. The workshop started with the attendees expressing their evaluationsof the DMC’s activities to date and expectations for the future. Then, a keynote address titled “Digital Libraries and Digital Editions” and four sessions(“Capturing, Modeling, and Archiving of Human Activities,” “Context Creation and Management for Multimedia Data,” “Digitization of Rare Books andManuscripts,” and “Digital Media and Networking Technology”) were held in the course of the following two days of the workshop. The two-day event
welcomed many Japanese and overseas researchers, as well as British media representatives.

Research Centers

20

Cooperating personnel at Keio…33

Temporary Researchers…24

RAs…27

International Collaboration Section
This section has overseas centers in the US, UK, China, and the Republic of Korea. It advances international collaboration
with research organizations and educational institutions, and has also introduced an internship program to foster young
researchers and professionals.

[Events in FY2004]

Research Institute for DigitalMedia and Content (DMC)

The DMC’s symposia and workshops are widely open to the public so that results of research activities may be disclosed to society.
15

November 2004

Open Courseware Workshop

6

December 2004

DMC Opening Symposium

29

January

8-9

February 2005

2005

The “Encouraging Development of Strategic Research Centers” of the Special
Coordination Fund for the Promotion of Science and Technology, MEXT

Keio University was selected as one of the “Encouraging Development of Strategic Research Centers,” a program of the Special Coordination Funds
for Promoting Science and Technology of the Ministry of Education, Culture, Sports, Science and Technology (MEXT), in FY2004. The goal of thisprogram is to foster excellent researchers and personnel of internationally competitive standards, and to establish an efficient research center throughstructural reform of existing R&D organizations based on outstanding vision and leadership on the part of top management. The Research Institute for
Digital Media and Content (DMC) promotes digitization of any contents residing not only at Keio but also throughout society, aggressively transmits
them from Japan to the international community, and leads the way in generating and disseminating new knowledge to the knowledgebased society of the 21st century. The DMC also advances the activities of the Digital Media and Content Consortium in order to engage in cooperation
with businesses.

DMC Symposium “The Virtual and the Real in l’Encyclopedie”
Exploring the Roles of Academic and Educational Institutions in Knowledge Sharing—The Possibilities in the Public Domain and Fair Use

9-10 March

2005

Keio Workshop on International Collaboration in Digital Media and Content

28-29 March

2005

DMC Workshop on Promoting the Digitization Project of Chinese Classics

Production Section
Digital content studios have been installed and put into operation at each of the five campuses, Mita, Hiyoshi, Yagami,
Shinanomachi, and SFC. Production facilities are also attached to the studios on Mita and Yagami Campuses. Each studio assigns
personnel and instructors for content production on-site to support and assist students and teaching and administrative staff increating digital contents.
• Mita Studio...B1, West Annex, Mita Campus• Hiyoshi Studio...4F, 5th Bldg., Hiyoshi Campus• Yagami Studio...3F, Information and Media Center for Science and Technology, Yagami Campus• Shinanomachi Studio...Institute of Integrated Medical Research 3S8, Shinanomachi Campus• Shonan Fujisawa Studio...B1, Shonan Fujisawa Media Center, Shonan Fujisawa Campus

Advanced Research Section
The Advanced Research Section is comprised of six research units.
• Content Design Application Research Unit
This unit contextualizes existing contents in three categories (i.e., goods, information and people) through digitization, and aims to conduct research on memory accession systems for the community, to design, classify, and combine each of the contents, and to consequently create new content.
• e-Learning Unit
This unit pursues the nurturing of instructional designers as professionals by developing processes for converting e-Learning content into educational materials. It also conducts research on
desirable forms of e-Learning application at institutions of higher education, cooperating with research institutes in Japan and overseas.
• Advanced Media Technology Unit
This unit promotes research and development of leading-edge media technologies that serve as the foundation for creating attractive media contents. It provides communication environmentsthat facilitate cross-sectional collaboration between studios and develops easy-to-use authoring tools.

Context Integration, System Research and Development Section

For Inquiries:

This section contemplates and builds the ideal shape of the systems for integrating, accumulating, and disseminating thecontent scattered throughout Keio, as well as the content newly developed and created at both the Advanced Research andProduction Sections.

The DMC
c/o Keio University
2F, West Annex, 2-17-22 Mita, Minato-ku, Tokyo 108-0073
Tel: +81-3-5418-6432
Fax: +81-3-5418-6437
E-mail: info@dmc.keio.ac.jp
http://www.dmc.keio.ac.jp/en/

Research Centers—Nowton Court Keio University/Research Institute for Digital Media and Content (DMC)

Keio University Annual Report on Research Activities 2004–2005

The HUmanities Media Interface (HUMI) Project of the Humanities Media Research Center at Keio University conducts research on digitalarchiving of rare and valuable books and manuscripts. The digital photography and related imaging technologies developed through the project havebeen contributing to the preservation and disclosure of rare and valuable books both in Japan and overseas. Since the spring of 2001, the HUMI Project,based at Nowton Court, has implemented digitization of valuable books of global importance in Europe, including the Bury Bible (Cambridge
University), the Caxton Press edition of The Canterbury Tales (The British Library), the Nara Ehon (The British Library, Chester Beatty Library),
Gutenberg Bible (Pelplin Diocese Library, National Library of Scotland) and the Winchester Manuscript of Le Morte D’Arthur (The British Library). HUMI
Project also hosted the “Nowton Court Colloquium on the History of the Book and Digitization” in 2002 and 2004, where experts in the fields of historicalbibliography, English literature of the Middle Ages, the history of books, art history, and digital archiving met together to discuss the digitization of rareand valuable books from varied points of view.

• Advanced Content Technology Unit
This unit creates advanced and next-generation contents through research and development of, for example, technologies that capture three-dimensional contents, generate user interfaces,
and reconstruct towns using virtualized reality technology.
• Networks and Security System Unit
This unit experiments with graduate/undergraduate teaching using a highly realistic course instruction system. Run over ultra high-speed networks and based on a framework of international
collaboration, the system is unfettered by the time and regional differences that pose obstacles in the case of traditional schooling.
• International Intellectual Property and Standardization Strategy Unit
This unit considers rules and regulations concerning digital intellectual property centered on copyrights, and conducts research on digital copyright management systems. It also works withthe e-Learning Unit to develop e-Learning materials for interdisciplinary education which nurture professionals in the area of technology standardization.

KEIO U-honbun̲E 05.11.29 7:36 PM ページ 21

Topics: Partnerships and Collaborations
Any organization which grows in size is prone to becoming compartmentalized, and a university is no exception. Keio University established theOrganization for Research Advancement and Administration (ORAA) in October 2003 to enhance the university’s ability to generate new and innovative
research overall through horizontal alliances that minimize the adverse effect of vertically divided administrative functions. Today’s universities are being
called upon to disseminate research outward rather than keep it behind walls. Research collaboration becomes more and more important, going beyond
physical distance between the campuses and disciplinary boundaries.
A variety of new approaches for research collaborations at Keio from FY2004 onward will be introduced in this section.

In addition to orthodox, discipline-based
events, the Center for Research Promotion tried forthe first time to organize an interdisciplinary
symposium in January 2005 at the Mita Campus.
Titled “Symposium for Leading-edge Science andTechnology: Frontiers of Bioscience Research and
its Outlook for Practical Application,” and based on
the common thread of life science, the symposium

aimed at introducing to the public the current state ofresearch from foundation to applications in thefields of science and technology, information
science, and medical science. After the symposium, the participating researchers and corporate
executives exchanged frank and lively views andopinions at the reception.

Panel Discussion at “Symposium for Leading-edge Science andTechnology”

1 Promotion of Exchanges between Keio Researchers
Breakfast Meeting for Interdisciplinary Exchanges

21

October 2004

Professor Keigo Komamura

Faculty of Law“Between Vengeance and Forgiveness”

January 2005

Instructor Masahiro Toda

School of Medicine“Translational Research”

February 2005

Associate Professor
Nobuyuki Yamasaki

Faculty of Science andTechnology“Distributed Real-time Processing
Technology for Sustaining Secure and Safe
Infrastructure”

March 2005

Associate Professor
Manabu Omae

Graduate School of Media andGovernance“Development of Automatic Driving Vehicle
and its Prospect”

April 2005

Professor Yoshio Higuchi

Faculty of Business andCommerce“The Analysis of Trend toward Income Class
Stratification and its Effect on the Marriage Ageand the Number of Children based on KeioHousehold Panel Survey”

June 2005

Assistant Professor
Yuko Kasuya

Faculty of Law“Explaining Divergence and Convergence ofParty Policy Positioning in Two Party Systems”

July 2005

Professor Toru Takebayashi

School of Medicine“Strategy for Disease Prevention Based on
Epidemiologic Approach: Bridging between
Medical Science and Society”

University-hosted seminars and symposia
have generally centered on individual research
institutes and groups in related fields of study.
Typical examples are the SFC Open Research
Forum (ORF) staged each year in November at
Roppongi Hills by Keio Research Institute at SFC(see page 13), and the Keio Techno-Mall hosted
every December at the Tokyo International Forum by
Keio Leading-edge Laboratory of Science andTechnology (KLL) (see page 9).

the entrance hall lobby to give visitors a real sense of“IT Returns to the People.”
Keio University is determined to deepen
exchanges and cooperation with society and totransmit research results to society in the form of
symposia and other media.

‘Design the Future’ symposium: visitors viewing booths

3 ‘Organization to Organization’ Research Collaboration
Cross-disciplinary Industry-Academia
Collaboration Project
Assistant Professor Yuko Kasuya giving a rousing lecture

2 Transmission of Research from the University to Society
Symposia

Associate Professor Toshiharu Furukawa of the
Law School and School of Medicine also introduced visions and leading-edge technologies
based on their own expertise.
Finally, at the panel discussion titled “Security
and Regional Health Care in an IT Society,”attended by the three Keio speakers and Professor
Yoshio Higuchi, Faculty of Business and Commerce, aremote real-time communication with a gigabyte
high-speed line was demonstrated to speak livewith medical doctors at Suginami-ward’s Ishi Kaikan(Medical Hall), 20 km away from the university. It
looked and sounded real and completely natural
without any lag in either image or hearing, as if thepanelists and the doctors were in the same room.
In conjunction with the talks and in cooperation
with several corporations, plastic optical fibers,
displays, and some of the latest IT products andtechnologies were displayed in four booths set up in

Program of “Keio Symposium for Leading-edge Science and Technology”

January 2005

Title

Speaker“Molecular Mechanisms for Maintaining the Stemness of
Hematopoietic Stem Cells”

Professor Toshio Suda, School of Medicine“Therapeutic Strategies for the Treatment of Central Nervous Diseases”

Instructor Masahiro Toda, School of Medicine“Development of Immunotherapy and Gene Therapy through Basic
Research on Cancer Biology”

Professor Yutaka Kawakami, School of Medicine“Metabolome Analysis and Cell Simulation”

Professor Masaru Tomita, Faculty of Environmental Information/
Institute for Advanced Bioscience“Biosimulation”

Professor Makoto Suematsu, School of Medicine“Total Analysis System for Drug Discovery”

Professor Hiroshi Yanagawa, Faculty of Science and Technology“Noninvasive Diagnosis of Ischemic Heart Disease with
Multidetector-row CT”

Professor Sachio Kuribayashi, School of Medicine“Medical Robotics”

Professor Kohei Onishi, Faculty of Science and Technology;
Professor Yasuhide Morikawa, School of Medicine“Key Success Factors for Japanese Bio-tech Ventures”

Professor Hiroshi Nakamura, Graduate School of Business
Administration

Panel Discussion on “the 21st Century Bioscience Research of Keio
University”

Professor Kuribayashi, Professor Yanagawa, Professor Tomita,
Professor Kawakami, Professor Suda, and Professor Suematsu

On June 1, 2005, Fast Retailing Co., Ltd.
(UNIQLO) announced a scientifically-designed
sportswear named "BODY TECH". This was theresult of a joint research contract signed in FY2004
between the company and Keio University through its
Center for Research Promotion. The joint research
involved three university organizations: the Faculty of
Science and Technology on Yagami Campus, theSchool of Medicine on Shinanomachi Campus, andthe Sports Medicine Research Center on Hiyoshi
Campus. The sportswear has been commercializedwith technologies developed by Professor Shohei
Onishi, Vice-Director of the Sports Medicine
Research Center. The special cut of the stretch
fabric is designed to reduce muscular fatigue,
offer breathing support, and limit elevation of bodytemperature. BODY TECH has sold well and an
additional lines produced through the joint research
will also enter the market.
This particular project was led by a coordinatorfrom the Center for Research Promotion. The coordinator and UNIQLO discussed and negotiated theconcept of the research, specific goals for productdevelopment, marketing analysis, and the roles
and responsibilities of both sides. In the meantime, the coordinator approached researchers at
the university in relevant fields and succeeded inlaunching the business-academia project consistingof a joint force of three university organizations
and a company.
It is often the case that joint and/or commissioned
research projects start on the initiative of personalconnections between a university researcher and acompany, but the UNIQLO project is a good example
of utilizing the Center for Research Promotion as acontact point for collaboration. A key factor
behind the success in quickly concluding the contract
for the project was using the center as a one-stop
contact point, because it benefited the company tonegotiate with only one counterpart representing
the university. At the same time, the researchers
could take advantage of the center to avoid often
time-consuming administrative burdens in contracting

and project management, despite the size andcross-sectional nature of the project.
Keio University will continue to promoteindividual joint and commissioned research projects asin the past, but will also actively seek to nurture
research cooperation with other universities,
research institutes, and the government and private
sectors through an organization-to-organization
approach that utilizes the combined potential of
the university as the whole.

Professor Onishi delivering an explanation to the press

22
Topics: Partnership and Collaborations

Keio University Annual Report on Research Activities 2004–2005

Keio’s campuses are dispersed throughout theTokyo and Kanagawa areas, and young, front-line
researchers are often heavily caught up in routine
duties, leaving limited time for researchers fromthe different campuses to actually meet. To
increase the chances of contact, and encourageinterest in other fields of study, the Center for
Research Promotion, at the suggestion of the advisoryboard, started monthly breakfast meetings withcoffee and sandwiches.
At the breakfast meeting, the lecturer for the
day gives a talk on his/her own recent research
topics and then participants conduct free discussion
with the advisory board members. The discussions
are always lively and high-spirited. In somecases, a political scientist may throw questions
from an alien perspective at an engineer, and inothers, researchers from the humanities and thesciences surprisingly share a common awareness of
the issues.
The breakfast meeting is just a first and small
step toward offering a meeting place forresearchers from different fields. The second step tobe taken for all of Keio University is the provision ofeffective support and necessary services to leading
researchers of the next generation.

While the January symposium was mainly
directed at business people, another cross-sectional
symposium entitled “Design the Future: IT Returns to
the People” in July 2005 targeted students and thegeneral public as its audience. The central theme
implied in the title was how changes in technology
could positively impact your future life, and whatshould be done in order to take advantage of such
positive changes. Lectures and a panel discussion
were held on IT utilization in education, healthcare, and security, on safety and security and on
technologies useful in everyday life.
Following opening remarks by President
Yuichiro Anzai, President Shouhei Kimura of
SECOM Co. Ltd. and Professor Tadahiro Ohmi of
Tohoku University gave keynote speeches.
Professor Jun Murai, Vice-President of Keio,
Director Yasuhiro Koike of Keio Leading-edge
Laboratory of Science and Technology (KLL), andKEIO U-honbun̲E 05.11.29 7:36 PM ページ 23

The 21st Century COE Program
Since its foundation in 1858, Keio University has been at the forefront of education and research in Japan. For 147 years, Keio has consistently
fulfilled its mission to contribute back to society through its academic and research achievements in fields such as industry and medicine. Keio has
also made substantial contributions through fostering the leaders of society and creating new areas of knowledge.
Keio University continues to be a driving force in creating the future of Japan and the global community.
The University’s application to participate in the 21st Century COE Program for FY2002 and FY2003 is an opportunity to advance its fundamental
mission through two main focuses: neutrality and a firm commitment to society. The 21st Century COE Program opens up new possibilities to focus upon
the creation of significant intellectual values and human resource development, while remaining impartial and unaffected by the short-term trends ofsociety. Keio University will reinforce its commitment to society by actively contributing to discussions of current social issues.
Keio University aims to become a leader in the global society of the 21st century through the creation of dynamic development and integrationof these two focus points at an international level, based upon a unique elliptical model.

23

FY2002

Links to each of the 9 fields and 12 programs at Keio University are available at the following URL:
http://www.21coe.keio.ac.jp/index_en.html

FY2002

FY2003

Please refer to the Japan Society for the Promotion of Science website for more information
about the 21st Century COE Program:
http://www.jsps.go.jp/j-21coe/

P29

P30
24

Optical and Electronic Device Technology for Access Network

Program Leader: Professor Hiroshi Yanagawa, Graduate School of Science and Technology

Program Leader: Professor Toshiaki Makabe, Graduate School of Science and Technology

The program constitutes the international center for education and research to advance knowledge
in SYSTEMS BIOLOGY by promoting interdisciplinary research and training among engineering, biology,
and medicine assisted by informatics sciences (genome, proteome and metabolome), with the ultimate
goal of understanding and regulation of life function.

The mission of this program is to promote excellent-caliber academic research in the area of opticaland electronic device technology for access network, and foster young researchers with wide/deepknowledge and high-level research skills, who will be able to be leaders in the creation of innovative
device/information technology on a global scale.

Information Sciences, Electrical and Electronic Engineering

P29
Function Creation Oriented
Life-Conjugated Chemistry

Life Sciences
Chemistry, Material Sciences

Mathematics, Physics, Earth Science

Social Sciences
Social Sciences

The Focus of
Remaining Neutral from Society

Social Sciences

Medical Sciences

We define “life-conjugated chemistry (LCC)” as“the chemistry to improve the quality of life,
including safety, health, medical care, comfort, etc.”
This program aims to establish a center of excellence
for research and education on LCC, in which efforts
are focused on the creation of innovative functional
molecules and materials and the education of
students who practice LCC.

The Focus of Having
a Direct Commitment to Society
Infrastructure for a
Knowledge Society
Exploring New Entrepreneurial
Potentials

Creating Intellectual Values
Inspiring through Education

Interdisciplinary, Combined

Program Leader: Professor Haruma Kawaguchi,
Graduate School of Science and Technology

Fields, New Disciplines
Mechanical, Civil, Architectural and other Fields of Engineering

Medical Sciences

Humanities

P27
Toward an Integrated Methodology for the Study of the Mind—CIRM: Centre forIntegrated Research on the Mind—
Program Leader: Professor Taro Nishimura, Graduate School of Letters
A global research and education center will be established with the aim of studying thedevelopment and mechanism of the mind. Work at the center will combine the latest research findings insuch fields as brain science, neuroscience and behavioral genetics with the body of knowledge that has
been accumulated in such humanities fields as philosophy, linguistics, image theory, and informatics. As
well as developing an integrated methodology, the center will serve to foster the next generation ofresearchers, who will have mastered the application of this integrated methodology in multiple fields.

P30
Next Generation Media and Intelligent Social Infrastructure
Program Leader: Professor Hideyuki Tokuda, Graduate School of Media and Governance
We will establish an international research and educational center to investigate next generation
information infrastructure, digital media applications, and their social implications. Our goal is to develop
a new architecture for intelligent social infrastructure in the 21st century.

The 21st Century COE Program

Keio University Annual Report on Research Activities 2004–2005

Understanding and Control of Life’s Function via Systems Biology

KEIO U-honbun̲E 05.11.29 7:36 PM ページ 25

P28
Designing toward the Ordering of Political Society
in a Multi-cultural and Pluri-generational World
Program Leader: Professor Yoshiaki Kobayashi, Graduate School of Law

25

P28

P27

FY2003comparison between the generation responsible for contemporary society and the generation
who will bear that responsibility in the future. Education-related plans: providing research funds
for younger researchers on a competitive basis, as well as organizing graduate students toparticipate in surveys relating to the main area of proposed research, giving instruction on the,implementation of citizens attitudes surveys and related analyses. Moreover, in order to makeknown the results of research undertaken in foreign languages, along with the publication of aforeign language review, it is proposed to subsidize travel expenses for those presenting at
international conferences.
Through these research and educational approaches, we aim to establish a program,of global research and education, not only carrying out opinion surveys into citizens
attitudes, but effecting research and education of the highest international standard into
the topic of global civil governance.

Policy Innovation Initiative:
Human Security Research in Japan and Asia

Program Leader: Professor Naoyuki Yoshino, Graduate School of Economics

Program Leader: Professor Moriyuki Oe,
Graduate School of Media and Governance

Since the early 1990s, the Japanese economy has been in a long recession. Our 21st COE Program is premised on
the belief that the fundamental cause of this long lasting recession is the lack of high quality markets within theJapanese economy. We believe that improving the quality of Japanese markets is the key to revitalizing the economy.
Motivated by this belief, our program aims to reveal the determinants of market quality by combining theoretical andempirical analyses with a broad range of historical and institutional case studies.
On the one hand, the importance of “quality” has been emphasized in various facets of managerial sciences. On
the other hand, issues related to quality have not been fully examined in economics, perhaps due to difficulties
associated with quantifying a “quality.” In particular, market quality has never been presented as a subject for serious
economic analysis. Gathering leading economists and managerial scientists at Keio University, our program intends toshed light on this new research subject and hopes to develop a new school of thought guiding economic policymaking.
In order to conduct sound quantitative analyses of market quality, high quality data is indispensable. In order to build such data,in our program, we design and build longitudinal panel data; longitudinal panel data tracks, for a large number of economic agents,
activities of each agent over a long span of time. Unfortunately in Japan, unlike in the U.S. and Europe, the accumulation of
longitudinal data, in particular on consumption, remains poor. We are determined to make continuous and long lasting efforts tobecome a leading center of longitudinal panel data in Japan.
Data that we can confirm to be reliable will be made usable for public. We are certain that these data will greatly
contribute not only to understanding market quality but also to research in various fields of social science beyond our
research theme.

The purpose of this program is to establish a
network of research and training organizations in Japanand Asia. This network will enable researchers andpractitioners to cooperate in finding the “problems” inneed of solutions, in identifying and developing theresources to be mobilized for the solutions, and ingenerating consensus in the methods of solving the
problems. We also aim at realigning existing methods ofinquiry in a manner conducive to finding and solving the“problems” attendant upon the rapidly increasingpressures of globalization, demographic change, andenvironmental change. Our purpose is to develop a newmode of analysis and practice for effective policy
formation and to form a new policy innovation“community” where scientific and practical knowledge
can be joined.
As enunciated in the 1994 Human Development
Report of the UNDP, “freedom from fear and freedom fromwant” represent the essence of human security. We join inthis formation of policy imperatives. The specific issues
requiring innovative policies for promoting “human security”
are diverse. Common to all these issues are the threats andthe unmistakable condition of insecurity each poses to theindividuals, to the communities, and to the regions involved,
regardless of their stages of economic development.

P32
Social Sciences

Integrative Mathematical Sciences:
Progress in Mathematics Motivated by
Natural and Social Phenomena
Program Leader: Professor Yoshiaki Maeda,
Graduate School of Science and Technology
The Integrative Mathematical Sciences
program is designed to open up new horizons inmathematics by bridging the gaps between puremathematics and application-oriented mathematics,
and to investigate new concepts and leadershipmethods for mathematical sciences. The core of theresearch and educational program is built on puremathematics, as supported by data science andexperimental mathematics. Data science serves as
the interface to various data-intensive phenomena,and experimental mathematics supports theexperimental aspect of mathematical sciences.
The main objective of our program is topromote the construction of international
educational and research centers throughintegrating these three aspects of mathematicalsciences. To facilitate our efforts further, the Center
for Integrative Mathematical Sciences at Keio willbe established under the auspices of the President
at the earliest possible opportunity.
As well as our research projects, we have astrong mandate to encourage Ph.D. students andyoung researchers internationally. For this purpose, wehave already started weekly interdisciplinary seminars
and colloquia to enhance interdisciplinary exchanges.
Another important aspect of our COE programs
is domestic and international collaborations inmathematical sciences with educational andresearch institutions overseas. We also invite
researchers to give lecture series for graduate
students, both to inform the students of progress inrecent important problems in mathematics, and toencourage research collaborations with the COE
program. We also plan to organize an international
workshop each year.

FY2002

FY2003Mathematics, Physics, Earth Science

Mechanical, Civil, Architectural and other Fields of Engineering

P32
Social Sciences
Information Sciences, Electrical and Electronic Engineering

Life Sciences

System Design: Paradigm Shift fromIntelligence to Life
Program Leader: Professor Kazuo Yoshida,
Graduate School of Science and Technology

The Focus of
Remaining Neutral from Society

Social Sciences

The Focus of Having
a Direct Commitment to Society
Infrastructure for a
Knowledge Society
Exploring New Entrepreneurial
Potentials

Creating Intellectual Values
Inspiring through Education

Interdisciplinary, Combined

Fields, New Disciplines
Chemistry, Material Sciences

Humanities

Medical Sciences

Medical Sciences

P31
Basic Study and Clinical Application of Human Stem Cell Biology and Immunology:
Approaches Based on the Development of Experimental Animal Models

P31
Establishment of Individualized Cancer Therapy Based on Comprehensive
Development of Minimally Invasive and Innovative Therapeutic Methods

Program Leader: Professor Hideyuki Okano, Graduate School of Medicine

Program Leader: Professor Masaki Kitajima, Graduate School of Medicine

The Keio University Graduate School of Medicine boasts an excellent staff in two academic fields: (1) stem cell biology andregenerative medicine, and (2) immunology and autoimmune disease research using animal models of human diseases. The COE
takes maximum advantage of the traditional joint research system approaches based on the development of experimental animalmodels since the founding of the school, and while ensuring ethicality and safety based on the achievements of basic medicine, thebasic and clinical staffs collaborate in endeavoring to elucidate the pathophysiology of incurable diseases and to develop newtreatment methods. It will form a “self-renewing” educational center that will foster and turn out many researchers with a broad
perspective. The COE will be characterized by I) incorporation of basic biology, taking advantage of Drosophila genetics, into the
medical area, II) development of in vivo experimental medicine using human cells and original animal models of human disease, andIII) application of the results by the university hospital that possesses state-of-the-art clinical capabilities. It will also establish an
evaluation system that will enable the maintenance of high-level studies by introducing research projects at the Research Park.

In this COE program, we will attempt to establish individualized cancer therapies based on
the comprehensive development of minimally invasive and innovative therapeutic methods
through translational research. Research will be conducted in three main areas: 1) development
of diagnostic methods enabling individualized treatment, including genetic diagnosis and new RI
imaging; 2) development of minimally invasive treatments, including endoscopic and robotic
surgery; and 3) development of new cancer treatments, including immunotherapy, gene therapy
and molecular target therapy. This research will be mainly performed at the Keio University
Center for Integrated Medical Research, which has several new research facilities like theLaboratory Animals Center, RI Center and Central Research Laboratory, as well as at Keio
University Hospital. To conduct this program efficiently, strong collaboration between the basic
and clinical departments of the Keio University Graduate School of Medicine and the Graduate

This COE aims at establishing a global collaborativeand educational research center of excellence based on thesystem design engineering which was initiated by Keio
University. In this COE, an important role will be played in
the mechanical and architectural fields of engineering byleading in the 21st century the paradigm shift to life for theengineering developed historically from high performancetechnology to intelligence technology in the 20th century. In
order to create harmony in the world of the natural entities
and artifact systems interacting each other, this COE
focuses on the characteristics of life as a system as well as
various life functions and creates a new design
methodology of mechanical and architectural systems which
are enabled to be interactive among inner components andouter systems by embedding design information including
rules of interaction into artifact systems.
In order to achieve the objective of this COE, thesystem design engineering will be further developed as a
backbone of the COE and several product innovations withrespect to architecture, robotics, energy/bio systems and so
on will be explored. This COE program will provide
graduate school students and young researchers a good
opportunity to challenge research through uniqueeducational programs such as overseas internship andcurriculum of leading-edge design school.

School of Science and Technology as well as between Keio University and outside academia,
and industry will be required. The center s Shinanomachi Research Park will provide research
space for collaborations. Updated cancer research information on basic and clinical topics will
be made available to graduate students, young researchers and medical doctors to enhancetheir research capabilities. International symposia and worldwide teleconferences will help toprovide a global perspective on learning. Through these efforts, we will attempt to establish aworld renowned cancer center that can quickly translate basic research into clinical applications
while training the next generation of researchers and medical doctors needed for the futureadvancement of cancer medicine.

26
The 21st Century COE Program

Keio University Annual Report on Research Activities 2004–2005

With the globalization that has been progressing in recent years, clashes in the areaof multiculturalism have made themselves apparent in many states and societies. On theconsideration that these problems cannot be resolved at the level of political leadership,alone; the program proposed will establish mechanisms to clarify the ways citizens
attitudes is promoted, developed and changed, and to consider the direction in which
multicultural communities are moving.
,
The eventual aim is to establish a “multicultural citizens attitudes research center”,
and to establish an enlarged “citizens attitudes data archive,” targeted at a variety of,countries. Together they will constitute Japan s first internationally-oriented humanresearch network. Research plans: to increase data and related analyses regarding,
citizens attitudes in a multicultural world; establishing the causes of conflicts, while
carrying on investigation into conditions that will make it harder for such conflicts toarise. Research will be undertaken into the outlook for political society in the 21st century:
the differences in attitudes of political society within multiculturalism in particular

Development of a Theory of Market Quality andan Empirical Analysis Using Panel Data

KEIO U-honbun̲E 05.11.29 7:36 PM ページ 27[Humanities] FY2002

27[Social Sciences] FY2003

Toward an Integrated Methodology for the Study of the Mind—CIRM: Centre for Integrated Research on the Mind—

Designing toward the Ordering of Political Society in a Multi-cultural and Pluri-generational World

Program Leader: Professor Taro Nishimura, Graduate School of Letters
http://www.cirm.keio.ac.jp/en/index.php

Program Leader: Professor Yoshiaki Kobayashi, Graduate School of Law
http://www.coe-ccc.keio.ac.jp/en/
To promote the doctoral and post-doctoral researches of young scholars,
CIRM had, from its outset, posts for research fellow and COE researchers.
Research fellows include mostly post-doctoral scholars from Keio and foreign
institutions, whereas COE researchers (both full-time and part-time) are mostly
doctoral candidates in the closely related fields. There is also annual research
grant scheme for young scholars; in 2004-2005, the grant was offered to 15
individual researches by graduate students in the Ph.D. course. In 2005-2006, wehave considerably increased the budget for this and are subsidizing both doctoraland post-doctoral researches by young scholars. The CIRM has so far publishedthree collections of essays in English, Comparative Analysis of Mind, Image andReasoning, Minds of the Past. In all of these, research fellows, COE researchers,
and doctoral candidates at Keio Graduate School are active contributors.

As a program dedicated to the promotion of research on public opinion
and attitudes in a global and multicultural world, building international
research networks constitutes one of the core strategies of the Center for Civil
Society with Comparative Perspective. The Center has established collaborative
partnerships with 30 universities and 33 researchers both in and outside
Japan, including, for example, an ongoing joint project on public opinion survey
and analysis jointly launched and managed with Yonsei University, Korea. To further facilitate research networking, the Center regularly organizes workshops andhosts an annual symposium. In 2004, our symposium had 38 speakers fromother Japanese universities and 13 speakers from abroad, attracting a total of 500
participants. The Center’s publications also serve as an important link with othereducational and research institutions in disseminating our research efforts. The COECCC Newsletter and the Center’s web site (http://www.coe-ccc.keio.ac.jp),
regularly updated in Japanese and English, provide an easily-accessible source of
information about our research activities. Our English-language academic journal,
the Journal of Political Science and Sociology, has been added to the librarycollections of more than 60 universities worldwide. The main work of associatedresearchers has been compiled in a 15-volume book series entitled Dynamics ofCivil Society in a Multicultural World, published in March 2005, and some part ofthe series is also due to be published in Korean.
The Center also puts one of its central objectives the education and trainingof young researchers, for which four strategies have been developed. To
strengthen international competitiveness, support has been given to
doctoral students wishing to present papers at international conferences or in
English-language journals in the form of “academic writing” and “academicpresentation” seminars. At the same time, we host seminars and workshops given
by visiting professors or researchers from abroad to encourage active
exchange of ideas and knowledge. For practical training, we have launched 26
graduate courses through which students can participate in actual research
projects led by their teachers. In terms of competitive selection ofresearchers, the Center adopts an open recruitment policy for the posts of
COE research fellows and assistant researchers. Finally, research grants areallocated to graduate students and young researchers through an open competition, while visiting fellowships are made available to overseas students. The
result of the above strategies can be seen in the number of doctorates
awarded to those associated with the activities of the Center, with the total of 30
students obtaining their doctoral degrees between 2002 and 2004.

“Japan-France Joint Symposium” (October 2004 Mita Campus)[Social Sciences] FY2003[Social Sciences] FY2003

Development of a Theory of Market Quality and an Empirical Analysis Using Panel Data

Policy Innovation Initiative: Human Security Research in Japan and Asia

Program Leader: Professor Naoyuki Yoshino, Graduate School of Economics
http://www.coe-econbus.keio.ac.jp/

Program Leader: Professor Moriyuki Oe, Graduate School of Media and Governancehttp://coe21-policy.sfc.keio.ac.jp/en/index.html

The purpose of this research is to enhance quality of the market function
which was not fully analyzed in economics in the past. In order to analyze thequality of the market, the analysis of the panel data of households is required
not only for Japanese households but also Asian households. Furthermore, firmlevel data including small business data, public expenditure data etc. will becollected to analyze qualitative changes in various market. Based on theseanalysis, the new economic policy recommendations of which improve themarket function will be addressed. Importance of the legal and institutional
factors will also be analyzed in order to improve the quality of the market.
International Network of Research
Two international journals are published from this research project. In the fieldof economic theory, International Journal of Economic Theory (Blackwell)which is jointly published with Economic Research Institute at Kyoto
University. In the field of policy research, Asian Economic Papers (MIT Press) is
jointly published with Columbia University and Korea Institute of International
Economic Policy (KIEP).
Research Network has been established, such institutes as CASS
(Chinese Academy of Social Sciences), Renmin University, National
Development Bank (China), Seoul National University, KIEP (Korea), Bank

Indonesia, MOF (Indonesia), University of Hong Kong, ISIS
Malaysia, Thammasat University (Thailand), MOF(Thailand), Georgetown University (USA), Free University(Belgium), Göteborg University (Sweden), OECD (France).
Research Center of the Panel Data Planning andAnalysis (Prof. Yoshio Higuchi), Research Center of
Economic Theory Analysis of Market Quality (Prof.
Makoto Yano) are established.
Continuous research on households data, firm level
data, public sector data Asian panel data will becollected in order to keep on conducting research.
Education and Research with Graduate Students
Many graduate students get jobs in various
universities and research institutes. Many students go
abroad, such as USA, England, etc., in order to continue
their research.
21st Century COE Program produces many joint
research works between faculty members and graduate
students.

What runs through the eight individual research groups of this program is thefollowing understanding. In order to devise a framework for policy innovations, 1)
we need to illuminate the alternative methods, by which the problems in need ofsolution can be properly addressed, which may displace and/or complement
the conventional method of solutions through market mechanism and publicfunding; 2) such alternative methods place the diverse actors, including thebeneficiaries of the policy solutions, within a dynamic and interactive process; 3)
we explore—and refine—the alternative methods either on a sustained
experimental basis or into the pioneering cases in various policy contexts andfinally 4) Sougouseisakugaku is thus a practical as well intellectual enterprise. Theinterim evaluation of the activities through the eight research groups for the
FY2004 is summarized below.
1) Integration of Micro-Macro Divisions for Observations and Analyses:
The need for integrating the micro observations in light of macro trends, andmacro policies in light of micro observations of their effects, is commonly
recognized as critical by all eight research groups, dealing with various policy
issues such as environmental degradation, pandemics, ageing populations,changing foundations for privacy, among others, which threatens the basis ofhuman security in developing and developed societies alike.
2) Rightful Place for Researcher: Social Commitment:
Given our overall understanding, first, we sustain our research deeply
rooted in the actual context of life where the detached observations are

replaced by the practical engagement in the very process of devising and revising
policy alternatives. Second, our observations, thus sustained, aim at generating
not only appropriate policy solutions but also a framework for promoting close
collaborations among the relevant individuals and organizations of private andpublic stature. We have maintained this form of social commitment in various
research sites, ranging from a rural Vietnam to an urban Yokohama, from acyber-space to a semi-urban China.
3) Development of New Methods:
Our positioning toward Sougouseisakugaku inevitably necessitates a new
innovative way of understanding human being. In addition to understanding
human being within the framework of human (in)security within the various
contexts of life, we recognize the need to probe the inner workings of humanminds, as expressed through textual and other methods of articulation. Taking
the advantage of the ever-improving tools of collecting and processing data,
we are gradually establishing the ways by which to capture the nature ofhuman interactions as they manifest in a complex and subtle realm of“semantics.” Though experimental, such method would eventually allow us toreduce the margins of error in understanding what is “expressed” and what is“intended” in human communication, thereby providing a firmer basis forpromoting policy coordination among the immensely diverse actors in thepolicy making process.

28
The 21st Century COE Program

Keio University Annual Report on Research Activities 2004–2005

In the year 2004-2005 “Centre for the Integrated Research on the Mind” haslaunched, in cooperation with various academic institutions outside Keio
University, a series of symposia, workshops, and conferences. One of them is the
symposium on “the Aesthetic of the Media/Cognitive Science and Virtual
Image” (as one of serial workshops on “Digital Art: New Technology, Creativity, andSociety”), to which a number of delegates from France participated (October 2004).
In Nov. 2004, an international symposium on “Animal Logic” was held at
Vienna in collaboration with Konrad Lorenz Institute for Ethnology and the two
institutions reached an agreement on further collaboration in research. In
December, a series of symposia, all open to the general public, were held at Mita
campus, on the topics including “the Linguistics of Mind and Feeling,” “IsEnglish necessary for elementary school education?,” and “Mind and the Act ofReading: A Comparative Study of Reading Figures in Eastern and Western
Art.” A workshop on NIRS, to which specialists from other institutions participate,are being held at a regular basis.
The interim report of the project indicated that the collaboration with otheracademic institutions were both effective and crucial for the development of
the integrated methodology for the study of mind, and as a result, further
international symposia and workshops, organized jointly with European
universities and institutions, are being planned. A second symposium on Animal
Logic is planned for summer 2005 at Budapest. There will also be the second
international symposium on “Images, Reason, and Reasonings” that will follow
up the first one at Ecole Normale Supérieure (March 2003), to be held at Mita
campus. An international graduate conference on Representations and Media isbeing scheduled for 2006 in England.

KEIO U-honbun̲E 05.11.29 7:36 PM ページ 29[Life Sciences] FY2002

29[Information Sciences, Electrical and Electronic Engineering] FY2002

Optical and Electronic Device Technology for Access Network

Program Leader: Professor Hiroshi Yanagawa, Graduate School of Science and Technology
http://www.coebio.keio.ac.jp/index.cgi?je=1

Program Leader: Professor Toshiaki Makabe, Graduate School of Science and Technology
http://www.coee.keio.ac.jp/index.cgi?je=1

Our program provides an internationally integrated center for advancing education
and research in the field of systems biology by promoting interdisciplinary research andtraining among graduates in engineering, biology, and medicine, with the ultimate goalof understanding and regulating biological functions through the application of
informatics science (genomics, proteomics, and metabolomics).
The center aims to utilize biological informatics to guide the development andapplication of novel biologically active molecular probes to regulate cell and organfunctions, as well as to reconstitute biological system functions in vitro and tomodulate them in vivo. To facilitate interdisciplinary research training of postgraduate students, the “Keio Bioscience Interactive Research Program (KBIRP)”
supports those who are interested in themes in integrative biology, from themolecular level to the organism level, as well as those aiming at integrating theengineering and biomedical sciences.
The center has focused on three major research areas or domains wherecutting-edge interdisciplinary biosciences have great potential to advance systems
biology. Broadly, the goal of KBIRP is to form a multidisciplinary bridge
between informatics and the biomedical sciences. (Domain 1) Collection andintegration of large-scale information on the genome, proteome, andmetabolome. (Domain 2) Development and Application of Biological Molecular
Probes. (Domain 3) Reconstitution and Artificial Control of Biological Functions.
Research activities at the center are coupled with educational programs on
several campuses of Keio University. The KBIRP supports postgraduate
students (Research Assistants: RAs) on these campuses so that they can share thesame curricula for understanding systems biology. RAs also have the opportunity
to apply for competitive research fellowships supported by the COE program andto visit foreign research laboratories in collaboration with COE. The KBIRP has
introduced a Diploma of the COE Research Cooperation Program for RAs whocomplete more than one program.
The center has already improved the environment for the study of systems
biology. In particular, there have been improvements in interactive and realtime networking infrastructure; this is important because the campuses of thethree schools are scattered over a large area of Japan. Remote lectures for COESystems Biology and progress workshops have been held via this high-performance

In this global era, international collaborative networks engaged inacademic fusion are essential for the achievement of scientific breakthroughs.
Our COE has filled this need through international workshops and symposia,
collaborations with international research institutions, hosting scholars fromoverseas and elsewhere in Japan at Keio and through research assistantships
and international internships.
For the past two years, under the auspices of our COE, speakers havebeen invited from across the globe to 5 international workshops located overseas
at Leuven (Belgium), Hammamet (Tunisia), San Jose (USA), Aalborg (Denmark),
Christchurch (New Zealand), and to 3 international symposia in Japan.
Mediated by these interactions, our research links are growing to include
universities and industries in USA, EU, and Asian countries, as well as inJapan. An example of collaboration targeting technology transfer from Keio toindustry is our interaction with Intel Microprocessor Research Lab. An example
of cooperation fostering technology innovation is the newly formed Network ofInternational Excellence, the goal of which is the design of new negative ion
plasma processes. It will be organized joint with the EIPAM program
comprising of universities in 15 EU countries supported by ESF funds.
Having visiting faculty members resident at Keio University is a core of
COE activity. Profs. N. Mason (Open Univ., UK), J. Horacek (Charles Univ., Czech
Republic), E. Pincik, (Academy of Science, SR), Z. Petrovic (Inst. Phys. Belgrade,SM), and S. Samukawa (Tohoku Univ.) were all short term Visiting Professors
engaged in collaborative research at our COE. In addition, Dr. P. Ventzek(Freescale Semicon., USA) visited as an Assoc. Professor participating in our
program. His activity included teaching a new course on “Plasma Micro
Processing” to graduate students.
One of the most important tasks of our COE program is to foster the industry

telecommunications system. The introduction of this system has also improved
sharing of information and scientific knowledge among members and aided
intensive training for the study of systems biology by fusing dry biology and wet
biology at separate campuses. During the past two years, a short-stay and goaloriented program matching the research themes of RAs has been established, inwhich RAs are recommended to study for 2-3 months at two or more subcentersin a cooperative framework. Introduction of this program has led to tangible
results in “the exploration and application of novel functions of erythrocytes bybiosimulation.” Three RAs of the Graduate School of Science and Technology,
five RAs of the Graduate School of Medicine, and five RAs of the Graduate
School of Media and Governance went through this short-stay program and two
RAs published an original paper in a very short time. In 2004, three workshops
for the education of young RAs were held at Tsuruoka, Yokohama, and Tokyo.
This year an intensive workshop was held at Shonan International Village at theend of September.
The center has been strongly promoting research cooperation with domestic
and foreign institutions and universities, including RIKEN, University of Tokyo,
Gunma University, Nagasaki University, Kyoto University, Osaka University,
University of California, Johns Hopkins University, University of Freiburg,
University College London, University of Montpellier, University of Orleans,
Shen Yang Pharmaceutical University, and others. Research cooperation withRIKEN is focused on plant metabolome and genome network analysis. In cooperation with RIKEN, one of our RAs obtained remarkable results on prediction of
the number of non-coding RNAs from the mouse cDNA database. Some RAs arestaying in American and European universities for short periods of time and thecenter has taken in many RAs from foreign countries, including China, South Korea,
Taiwan, Thailand, and Bangladesh.
Our program is being recognized as an internationally integrated
education and research center for systems biology, and the Institute forAdvanced Biosciences at Tsuruoka was awarded a prize for “IBM Shared
University Research,” which was reported in Nature. In 2005, the FirstInternational Conference on Metabolome was held in Tsuruoka in June, and an
International Symposium on Biosimulation was held in Tokyo in July.

[Chemistry, Material Sciences] FY2002

Function Creation Oriented Life-Conjugated Chemistry
Program Leader: Professor Haruma Kawaguchi, Graduate School of Science and Technology
http://www.lcc.keio.ac.jp/index.cgi?je=1
Research Activity and Collaboration
Talent Education
The midterm assessment reported that “life-conjugated chemistry is a
We have adopted a large number of graduate students as research associates
unique and appropriate subject toward the future chemistry and materials(RAs). In addition, we invited some other Ph.D. students as special RAs. RAs are
science.” It also reported that several highly-qualified achievements have been
assigned duties such as presentation at international conferences in abroad,brush-up of the English study, participation to “Life-Conjugated Chemistry”
resulted from this project. But the assessment gave some other comments
class and other special lectures. RAs and other graduate students of Keiowhich included that the target should be made more distinct and the project prove
University and Tokyo Institute of Technology will organize a joint symposium
the value of proposed approach.
autumn in 2005. A similar joint meeting had been held by graduIn order to make the target more distinct, we re-constructed ourate students of Waseda and Keio Universities. The RA stuproject into three groups, that is, the groups for material creation led
Environment/life
in harmony with recycling environmentdents
are going to contribute to Keio Techno-Mall and otherby function designing, for the one inspired by living body, and for the Materials
Organic/inorganic composite material alternatives
occasions to send out their own results.
one developed from hierarchical fabrication, and promoted the Environmentally sensitive molecular materials
object-aimed collaboration among the project members in each Creation of materials learning from the living bodygroup. Therefore, we set our goal to prove the value of life-conjugatedCreation of innovative
chemistry. We will realize it through intra- andfunctional molecules andmaterials
Creation of materials
international collaboration, for example, weCreation of materials
from hierarchicalfrom molecular design
signed treaty with the bioactive materials
structure search
Research Structure in Third Year of
research group in Yonsei University. We Multiple associative memory materials“Function Creation Oriented
Chemical sensing materials
High efficiency photoelectric conversion materials
Hierarchical assembly of responsive materials
will have three international symposium
Life-Conjugated Chemistry”
Optical control of magnetic properties using
Molecular device controlling living environment
self-assembled membranes
Lifestyle basics/medical goods/foodorganized by each group in 2005.
Lifestyle information/energy

LCC

awareness of Ph.D students through COE-RAs providing them with the opportunity to absorb a rich variety of expertise related to both “device technology” and“networking.” With the cooperation of industry (e.g., JEITA), more than 60 lectures
were given in 2004/5 to 30 COE-RAs exposing them to state-of-the-art technology
development to issues pertinent to industry in general. We are continuing ourInternational Internship Program. 8 RAs applied to study in 2004/5; in Harvard
Univ.; Carnegie Mellon Univ.; UC Davis; USC; Univ. of Cambridge; Univ. ofLondon; Royal Inst. of Tech. Stockholm. This has significantly broadened theirscientific network and promoted long term international research activity.
Through our activities in 2004, 92 journal papers were published, 30
invited talks and 156 papers were presented in the International Conferences, inaddition to 7 Progress- reports/Proceedings of our COE. As a result, our program
has been evaluated highly by institutions and universities worldwide for its
uniqueness and quality.

[Interdisciplinary, Combined Fields, New Disciplines] FY2002

Next Generation Media and Intelligent Social Infrastructure
Program Leader: Professor Hideyuki Tokuda, Graduate School of Media and Governancehttp://www.coe21.sfc.keio.ac.jp/index.html.en
Program Summary
The objective of the program is to develop a new architecture of the intelligent
social infrastructure which supports our life, environment, culture, education, andmedical care in the 21st century. The research will be conducted by the collaboration
among three groups, namely the next generation information infrastructure group, thenext generation application group, and the empirical social experiment group.
External Research Collaboration
The research center is organized by three research groups namely the next generation information infrastructure group, the next generation application group, andthe empirical social experiment group. It is our unique feature that three groups collaborate with local governments, educational institutes, research institutes and otherorganizations for empirical social experiments based on so called the skewered threelayers model. e-Governance group designed and implemented evaluation methods
and information sharing systems for educational services of local governments. It
was used at 12 high schools in Miyagi prefecture and elementary schools in
Adachi ward, Tokyo. It demonstrated that the effectiveness of the system forschool evaluation. e-Space group also provided the web services for digital earth
data in cooperation with NHK Special, called data map for 6.3 billion people,
using our COE servers. e-Learning group also collaborated with three junior highschools in Fujisawa, a junior high school in Taipei and Pusan, a university inBeijing, and four French universities, using our distance learning systems. The
next generation information infrastructure group evaluated the satellite-based
internet technique with Asian universities and 43Gbps optical links with the NTT
Network Innovation Laboratory. An e-learning system developed by the next generation application group was commercialized as Power-Rec system by Photoron Corp.

Human Resource Development
Our goal is to produce very active and high quality young researchers who canbe a leader of the society in the near future. As for training young researchers, we
hired 26 RAs in 2003 and 25 RAs in 2005 at the center.
Following “International Symposium on Interactive Society with
Information Commons” held in January 2004, we held “International Workshop on
Collaborate! In search for Intelligent Social infrastructure” in January 2005.
During the workshop, many RAs presented their collaborative research workand deepened their understanding of the intelligent social infrastructure. We
encourage every RA to participate in research activities as well as open discussions during the research meeting. We also try to spread research results by not
only traditional journal papers and conference proceedings, but also streaming
data via the COE server (http://www.coe21.sfc.keio.ac.jp/) for open public.

e-Learning

e-Governancee-Space

Multi-Language Education
Lifelong Modele-CareDistance Consultation
Math-Learning Modele-Gov. System
Complimentary Currency
Career Development
J-Resete-Space Systemg-Contents
g-IT Service
e-Community PlanningMedia Design

Smart Web

Digital Contents

e-Learning System
Smart Graphics
Mobile Media

Semantic Web
Associative Ontology
Web Accessibility

Micro Archiving
Digital Music
Museum Architecture
IP Management

Ubiquitous
Env.
Smart Space Tech.
Ubiquitous Interface

Networking
Streaming Tech.
Satellite-Based Internet

Cognitive andBio-physicalModel
Analytical Model

Multi
DataBase

Security &Privacy

Active MultiDB

Security
Privacy Control

Research Topics in 3 Layers

30
The 21st Century COE Program

Keio University Annual Report on Research Activities 2004–2005

Understanding and Control of Life’s Functions via Systems Biology

KEIO U-honbun̲E 05.11.29 7:36 PM ページ 31[Medical Sciences] FY2003

Establishment of Individualized Cancer Therapy Based on Comprehensive Development of Minimally Invasive
and Innovative Therapeutic Methods
Program Leader: Masaki Kitajima, Graduate School of Medicine
http://www.coe-cancer.keio.ac.jp/

31[Medical Sciences] FY2003

The Center for Integrative Mathematical Sciences has been established as aninternational research and education center by promoting the following projects.
1. Transverse Research Projects and International Collaborations
We started the Integrative Mathematical Sciences program with thefollowing two research and educational themes: “Non-commutative manifold
and discrete geometric constructs in the framework of non-commutative
geometry” and “Analysis of nonlinear phenomena in the framework of data
science.” In accordance with these themes, we organized nine ongoingseminars in which many related researchers from outside of Keio University
have taken part. Further, we held in total seven international conferences andworkshops in 2004: Workshop on the Navier-Stokes Equations (May 6th to 8thin Keio University), UK-Japan Winter School 2005 (January 9th to 12th inEngland), Cherry Bud Workshop 2005 (February 23rd to 26th in Keio University),
Non-commutative Geometry and Physics 2005 (March 4th to 7th in Shonan
Village), etc. Not only from within academia, but also many researchers fromoutside the university took part in these conferences and workshops. As aresult, we were able to collaborate in international research with many
universities in the UK, and we also received support from the London
Mathematical Society. In 2005, we have concluded the Poisson Geometry
Research Education Project with the Ecole Polytechnique Federale deLausanne in Switzerland. Plans to hold some international conferences andworkshops in cooperation with the European Mathematical Society, theAmerican Mathematical Society and the Mathematical Society of Japan are
currently in progress. We also cooperated with Peking University, one of ouraffiliate institutions, and are planning to hold an international conference
together. In addition, the research collaboration regarding quantitative risk
management with Zurich ETHZ and the international research collaboration
within Keio University have both progressed greatly.

2. The Nurturing of Talented People
In our role as a research support program for Ph.D. students and young
researchers, we have competitively selected and employed five postdoctoral
fellows (two from overseas) and 10 research assistants, and we supported
their research. Moreover, we carried out the following projects for the sake of the
training of the students and young researchers.
(1)

We invited productive world class researchers and held various lecture series tohelp the students and young researchers further their studies. The “Non-commutative
Transverse Research” group invited a guest professor every month and organized the“Pathways Lecture Series” which continued for three to five day periods. In this lecture
series, we invited not only Prof. R. Devaney of Boston University and the president of
IMU, Prof. J. Ball, but also 12 overseas and two domestic scholars to give lectures.
Further, a Nobel Prize winner in physics, Prof. G.’t Hooft, also gave a talk in this lecture
series in February. For its part, the “Data Science Transversal Research” group invited threescholars from overseas and organized the “COE Lecture Series.”(2) We invited Dr. P. Thomson, Prof. Shoshichi Kobayashi of UC Berkeley, and Prof. K. D.
Elworthy of the University of Warwick for one month as research advisers, providing the
Ph.D. candidates and young researchers the good opportunity of communicating with suchinternationally great researchers.
(3) In our annual UK-Japan Winter School, we cooperated with University of Warwick thisyear, and gathered both domestic and overseas students and young researchers. In addition to attending the lectures, they presented papers and held discussions with each other
there, and gained a great international experience.
(4) To support young researchers, we held the “Tateshina Young Seminar” concerning topology andgeometry in one of the Keio’s facilities, Tateshina Sanso. In addition, the “Combinatorics Young
Seminar” was held at the instigation of the combinatorics researchers.

Through these various activities, Ph.D. students graduated in large numbers
and were able to enter society. This year we had more than 11 applicants for the
Ph.D. program in the field of mathematics: the number of applicants accounted for
50% of all applicants in the areas of Fundamental Science and Technology.
Now we have more than 30 Ph.D. candidates in mathematics; this factdemonstrates that our COE program has already won wide recognition.

[Mechanical, Civil, Architectural and Other Fields of Engineering] FY2003

Program Leader: Professor Kazuo Yoshida, Graduate School of Science and Technology
http://www.coesys.keio.ac.jp/english_index.html

Program Leader: Professor Hideyuki Okano, Graduate School of Medicine
http://www.coe-stemcell.keio.ac.jp/• Development of interdisciplinary research environment by inviting prominentscientists from all over the world to COE-associated seminars and symposium.
• COE advanced special laboratory courses, i) Patch-clamp Recording course and ii)

Flow Cytometry course were offered.
• A flow cytometry core facility, a COE Stem Cell Biology/Immunology Research and

Education Center was established.
Establishment of COE Stem Cell Biology/Immunology Research and Education Center

Flow cytometry core facility

Program Leader: Professor Yoshiaki Maeda, Graduate School of Science and Technology
http://coe.math.keio.ac.jp/

System Design: Paradigm Shift from Intelligence to Life

Basic Study and Clinical Application of the Human Stem Cell Biology and Immunology:
Approaches Based on the Development of Experimental Animal Models

Role of CIEA in the Program
In Japan where there are high hurdles to be overcome in applying the results ofbasic research to clinical research, it is indispensable to foster preclinical researchusing animal models of human disease. The Central Institute for Experimental
Animals (CIEA) is deeply involved in the establishment of animal experimentation
systems for animal models of human disease to be useful in medicine based on thestrong belief that laboratory animals should support medicine, and also in theestablishment of in vivo experimental medicine to connect basic and clinical research.
Visiting Professors Tatsuji Nomura, director of CIEA, and Norikazu Tamaoki, deputy
director of CIEA, play important roles as members of the COE program.
Education Program• Monthly unpublished data presentations in English “COEX MEETING” will beheld for the purpose of information exchange among young investigatorsand promotion of joint research, and advanced graduate student and postdoctoral(PD) education will be supported.
• As a COE advanced lecture course for graduate students, Course of Molecular
Developmental Biology is being offered.
• Improvement of the teaching assistant (TA) system and research assistant(RA) system.
• “Bioethics Course” is being offered.

Integrative Mathematical Sciences: Progress in Mathematics Motivated by Natural and Social Phenomena

Cell processing center

This Center supports the strengthening of stem cell biology andimmunology education and research.

The aim of COE “System Design: Paradigm Shift from Intelligence to Life” isto establish a global collaborative and educational research center of excellence
based on system design engineering initiated by Keio University. This COE program
will play an important role in mechanical and architectural engineering byleading in the 21st century the paradigm shift for engineering toward life and awayfrom high-performance and intelligence technology in the 20th century.
To achieve this objective, system design engineering will be developed
further as the backbone of the COE and several product innovations withrespect to architecture, robotics, energy/bio systems symbiotic production system
will be explored. This COE program will promote human resources
development centered on graduate students in the doctoral program througheducational programs such as the Advanced Design School and theInternational Internship program.
The Advanced Design School is unique educational program which has
been started in 2004. The concept of this design school is that the productinnovation is essentially not simply technological setting but should be considered
in a larger context such as studies in society, economics, and cultures.
Therefore the design education should also aim for a comprehensive synthesis
encompassing design theory, design methodology, design technology,
manufacturing technology, IT technology, environmental engineering, marketing

management, psychology, and other fields. The Advanced Design School originatedwith the concept of design related to “life” or “system life technology”, and provides three courses such as Architectural System Design, Space System
Design, and Product and System Design.
This COE is providing an international internship program for graduate students
in the Ph.D. course whose research are very unique and promising to make successfulprogress. Students applying for this program will be sent to the related university or
research institute abroad for six months at the longest, and will be given
opportunities to make high-level joint research there. By carrying this program in both
directions, i.e., accepting excellent graduate students and post-doctoral fellows fromabroad, the COE project itself
will be stimulated and environment for international
research will be improved.
The purpose of this program is
to make successful progressof the research and to educate talented students forworld’s leading researchersof this field.

32
The 21st Century COE Program

Keio University Annual Report on Research Activities 2004–2005

Our goal is the formation of one of the world leading sate-of-the-art cancer
A cancer medicine curriculum that includes broad fields of cancer researchtherapy development centers capable of strategically developing translational
ranging from the basics to clinical practice is offered in order to train bothresearch studies that make full use of multidisciplinary treatment systems and ofinvestigators who are capable of understanding clinical problems, andthe rapid implementation of basic research results in clinical practice. To
clinicians who can grasp the foundations of new concepts for innovative cancer
achieve this goal, the research is performed in close collaboration with members
therapies. Sixteen seminars in the fields of bioethics, basic cancer research,of other university faculties, researchers in other academic institutions throughdiagnosis, and therapeutics were held in 2004. For promoting advanced
graduate school liaison (the Institute of Medical Science, the University of
research, the COE holds monthly research meetings to discuss research
Tokyo, National Cancer Center, National Center for Child Health andprogress for further promotion of translational research and collaboration. The COE
Development, National Hospital Organization Tokyo Medical Center, Central
set up Medical Engineering room where engineers from graduate school of science
Institute for Experimental Animals, etc.), and researchers in related industries
and technology and clinicians from graduate school of medicine work together inthrough the Research Park system in the Center for Integrated Medical
the medical campus, and Minimally Invasive Surgery Training Education
Research, Keio University. Collaborative cancer researches by the COE members
Center, which offer unique programs for training surgeons for endoscopic andand researchers from 12 companies
robotics surgery and where developed
are currently in progress. The COE
equipments are evaluated in the approHuman Resource Development
associated venture company, Institutepriate simulation system. To train young
Collaboration with Outside Institutions and Industriesof Gene and Brain Science, was supresearchers
withglobalview,
Graduate Sch
Graduate Sch
Diagnosis
Medicine
Sci and Techported by Ministry of Education,
International Teleconference was regu(Leader: Sakamoto)
Graduate
Overseas
Culture, Sports, Science and Technology.
larly held with internationally renowned
Minimally Invasive Innovative Therapy
SchoolCancerTreatment(Leader: Kawakami)
LiaisonInstitutes
These academia-industry-government
institutions, including Cleveland Clinic,(Leader: Kitajima)
IMSUT
Cleveland Clinic.Minimally Invasive Surgery
NCC
Mayo Clinic
collaboration efforts in this COE
Mayo Clinic, Technical University ofTraining Center
NCCHE
Technical
Univ
Munich.Medical Engineering Room
NTMC
etc.
program are well recognized.
Munich, etc. and young scientists are
CIEA
Research Park System
Intellectual Property
etc.
Collaborative researches withFor efficient training of young
encouraged to attend Keio University
Center12 industries
researchers, a research assistant (RA) Cancer Medicine Curriculumorganized international meetings, includingInternational
TeleconferenceTraining ofInternational. Symposia
Research Meetingsand postdoctoral fellow (PD) system
International Symposium for Life
Basic and Clinical Oncologists
was established (34 RAs, 9 PDs, and 7
Science and Medicine and the Keiotechnicians were employed in 2004).
Medical Science symposia.

[Mathematics, Physics, Earth Sciences] FY2003

KEIO U-honbun̲E 05.11.29 7:36 PM ページ 33

FY2004 Financial Position

Research-related Facilities and Libraries

Ended on March 31, 2005
Research Space for Rent
Keio University provides research space and incubation facilities for rent as indicated below. Please inquire in advance for vacancies, rental
qualifications, application procedures, application deadlines, etc.

1 Balance Sheet

As of August 2005

Million yen

33

278,238
182,126
27,18791,488
5,282

Liabilities
Fixed liabilities
Long-term borrowings
School bonds
Retirement allowance reserve
Pension reserve

OutlineResearch Space at the KLL(See pages 9-10)

Total of 32 rooms in Sousoukan Building on Yagami Campus
Size: 66.12m2 - 102.49m2; Total floor area: 2,519m2

58,221
8,160
4,510
29,485
16,066

Type A (for chemistry and biology experiments)
Type B (for applied physics experiments)
Type C (for experiments for heavy materials)
Type D (for experiments for light-weight equipments)

34

Type E (for various types of experiments)
23,301
254
34,55720
37
96,112
4
72
931
2
3,750
2,812
49,5896,522
32,431

Current assets
Cash deposits
Accounts receivable
Inventories
Negotiable securities
Assets for school trip deposits
Others65,061
25,125
12,854614
25,494113
860

Assets total

343,298

Current liabilities
Short-term borrowings *2
School bonds *2
Accounts payable
Advances received
Deposits
School trip deposits

31,207
1,916
2,012
12,651
13,047
1,468
113

Liabilities total

89,427

Institute of Integrated Medical
Research Building

Laboratory, Shin-Kawasaki
Town Campus

268,484
4,038
32,431
7,959
312,912

Balance of income and expenditure
Carried forward to next year

∆59,041

343,298

I-Building : 1,171.36m2
O-Building: 1,388.25m2
56 units in the Institute of Integrated Medical Research Building
Outline:Steel frame with a reinforced concrete structure; 2 underground floors, 9 above ground floors, and one penthouse floor*1 Specified assets
Assets reserved for specific purposes such as the “retirement allowance
reserve,” the “pension reserve,” and the “Second Fund.”Size: 96m2 - 124m2; Total floor area: 24,400m2*3 First fundAcquisition cost of fixed assets by self-financed imputed income such as
school land, school buildings, equipment and supplies, books, etc.
*4 Second fundAmount of assets such as deposits reserved for the purpose of acquiring
fixed assets.

Keio Fujisawa Innovation Village(See page 14)

To be completed by the end of March 2006

Facilities for Incubation and Industry-Academia
Joint Research (tentative name)
Developed by Tsuruoka City
(See page 18)

29 units, Size: 7m × 10m × 2.8m
Steel frame structure, 2 floors
Total floor area: approximately 3,700m2
Open for tenants in May 2006

Research Space at KLL*5 Third fundAmount of assets such as scholarships, research funds, and the like.
*6 Fourth fundAmount of funds that must be constantly maintained.

Total of liabilities, funds, and balance ofincome and expenditure

E-Building : 1,388.25m2

Shinanomachi Research Park
(See pages 11-12)*2 Short-term borrowings and school bonds
Current portion of “borrowings” and “school bonds (Jukusai ).”

Funds
Funds
First fund *3
Second fund *4
Third fund *5
Fourth fund *6
Funds total

K-Building: 1,388.25m2

Shin-Kawasaki Town Campus(See pages 15-16)

Source: Activities and Financial Position of Keio Gijuku: FY2004
Business Report

Library Collections
Keio University has five campuses: Mita, Hiyoshi, Shinanomachi, Yagami, and Shonan Fujisawa, each one of them developing leading-edge
research and education in various disciplines, and also high-level medical practice. The Media Centers, centering the library service, branch on each
campus to provide intensive support for all these specific activities.
As of 31 March 2005

Book Stocks

2 Income and Expenditure Statement
Million yen
All of Keio
(Keio Gijuku)
IncomeImputed income
Tuition and other student fees 43,156
Other fees
2,163
Donations *1
4,192
Subsidies *2
13,272
Income from asset
management *3
4,617
Income from business
7,082
Income from medical services 40,245
Miscellaneous income
2,286

University only

253
6,634
0
1,786

Expenditure
Personnel
Expenses for education andresearch *4
Expenses for generaladministration
Interest on borrowings
Loss on disposition *3
Provision for allowance for
doubtful accounts
Discretionary reserve

35,532
1,839
2,833
9,523

All of Keio
(Keio Gijuku)

University only

60,61932,09850,54625,848

3,285
232
1,525

773
109
209

33
——

0
——

Imputed income total

117,01358,400Total expenditure

116,241

59,037

Transfer to capital fund

∆8,945∆5,927

Income total

108,069

52,473Current excess over expenditure
Brought forward from last year
Carried forward to next year

8,172
50,86959,041

——
——
——

772

∆637

Imputed income total –Total expenditure

Source: Activities and Financial Position of Keio Gijuku: FY2004 Business Report
The settlement of accounts of the school juridical organization Keio Gijuku is a consolidated account of the following four sectors: the corporation,
the university (including research institutes and libraries), affiliated schools for integrated education (elementary, junior and senior highschools and a foreign language school), and hospitals (Keio University Hospital and Tsukigase Rehabilitation Center).

*1 Donations
Includes contributions in goods.
*2 Subsidies
Subsidies allocated to individual researchers, such as Grants-inAid for Scientific Research (Kakenhi) and Subsidy for Promoting
University Reform, etc. are not included in the total. Expenditures
corresponding to the subsidies are also excluded from those foreducation and research, accordingly.
¥9,313 million of the ¥13,272 million in total subsidies comes fromthe Promotion and Mutual Aid Corporation for Private Schools inJapan (PMAC). ¥6,629 million of the total accounts for generalsubsidies, and ¥2,684 million for special subsidies. The PMAC, on
behalf of the government, processes applications submitted byprivate schools nationwide and receives subsidies from thegovernment. The PMAC then allocates them to applicant schools. In
FY2004, a total of ¥289.8 billion of the subsidies was distributed to502 private universities.
Source: The Promotion and Mutual Aid Corporation for Private Schools ofJapan website: http://www.shigaku.go.jp/s_hojo_h16.htm

Collections by Material Type
Domestic
Books

Foreign
Books

Domestic
JournalsForeign
Journals

Journal Titles
Currently
Received

Electronic
Journal Titles

Number of
Databases

Number ofElectronicBook Titles

Number of
Seats

Mita Media Center

2,338,267

38%

41%

10%

11%

10,41419,066

187

1,627

1,104

Hiyoshi Media Center,717,137

56%

28%

07%

09%

01,75518,874

098

1,627

1,314

Shinanomachi Media Center,369,140

16%

13%

23%

48%

02,944

20,848

076

1,637

0,168

Information and Media
Center for Science andTechnology (Yagami)

331,728

25%

12%

16%

47%

02,287

20,033

082

1,627

0,373

Shonan Fujisawa Media
Center,318,074

55%

26%

12%

07%

02,173

21,030

113

1,957

0,917

Total

4,074,346

19,57399,851

556

8,475

3,876

*3 Income from asset management and loss on disposition
Revaluation from working assets is included in loss on disposition.
*4 Expenses for education and research
Includes the adjustment for depreciation and pharmaceuticals(amount actually used).

Mita Media Center

Shonan Fujisawa Media Center

Research-related Facilities and Libraries

Keio University Annual Report on Research Activities 2004–2005

AssetsFixed assets
Tangible fixed assets
Land
Buildings
Structures
Equipment and supplies foreducation and research
Other equipment and supplies
Books
VehiclesConstruction in progress
Other fixed assets
Land lease rights
Telephone subscription rights
Facility use rights
Deposits
Profit-making business capital
Long-term loans
Specified assets*1
School bond assets producing interest
Reserve assets for the third fund

FacilityKEIO U-honbun̲E 05.11.29 7:36 PM ページ 35

Research Funds at Keio University in FY2004

3. Research Funds by Type

AmountResearch funds at Keio University from national and local public institutions, private businesses, and university funding, etc., totaled approximately ¥13.9
billion in FY2004. These funds include the Special Coordination Fund for the Promotion of Science and Technology “Program to Encourage theDevelopment of Strategic Research Centers,” of the Ministry of Education, Culture, Sports, Science and Technology (MEXT). This research grant projectprovides intensive support to organizational reform efforts for the purpose of developing an excellent research infrastructure. Others include funds forthe 21st Century COE Program for which Keio University won 12 projects, the largest number for a private university.
In the following, data on research funds is categorized by campus, affiliation of researcher, type of funds, and field of research.

The number of projects funded by specified
contributions results in the largest of all whencompared to the other types of funding. Funds
from subsidies come first in terms of amount.
Funds from subsidies, commissioned research,and specified contributions account for
approximately 90% of the total research funds.

1%
Joint Research

3%

Amount0.2%

Keio University Annual Report on Research Activities 2004–2005

Mita Campus
Hiyoshi Campus
Yagami Campus
Shinanomachi Campus

Hiyoshi Campus
Mita Campus
Shonan Fujisawa
Campus

1.6%

13.9%

Shonan Fujisawa Campus
Shin-Kawasaki Town Campus
Tsuruoka Town Campus

Joint Research:
Collaborative research through personnel exchanges
and/or sharing technology/facilities under the joint
research agreement, with or without payment ofresearch funds.

22.0%
Number of
Projects

Contracts:
Research under a contract agreement.
20

40

60

80

100

Thousand yen

CampusNumber of Projects
248

Hiyoshi Campus

152

220,735

Yagami Campus

509

3,061,612

Shinanomachi Campus

1,580

5,029,019

Shonan Fujisawa Campus

499

3,198,878

2

32,500Shin-Kawasaki Town Campus
Tsuruoka Town Campus
Total

Technical Guidance:
Research involving technical guidance such as development of equipment or apparatus.

AmountMita Campus

9426,902
13,885,447

40

60

80

100

36

1%
Thousand yenType of Funds

Number of Projects

University Funds

419

416,014

Subsidies

844

6,186,984

GrantsAmount75

131,297

1,093

1,704,757

Commissioned Research

376

4,926,284

Joint Research

178

355,713

Contracts

12

164,248

Technical Guidance

2

150

2,999

13,885,447

Specified Contributions

Total

1,915,801

2,999

20

GrantsYagami Campus

0

0

12%

Commissioned Research:
Research commissioned by government and otherpublic offices, as well as private enterprises.

Amount36.2%

Specified
Contributions

Specified Contributions:Contributions earmarked for research activities.

23.0%

Shinanomachi Campus

Number of
Projects

Grants:Research expenses provided mainly by foundations
for the purpose of improvement or accomplishmentof research.

3.1%

45%

Research Funds at Keio University in FY2004

35

The data in this section presents researchfunds by campus. The Shinanomachi Campus
came in first in both the amount and the numberof projects, while the Shonan Fujisawa Campus
and the Yagami Campus are second in theamount collected and the number of projects,
respectively.
Note that the figures for the two
campuses in the table do not necessarily reflect
the amount used and many of the projects are
conducted at the Shin-Kawasaki Town and the
Tsuruoka Town campuses (called the Frontier
Research and Education Collaborative Square(K-FRECS)). The K-FRECS act as hubs for
cutting-edge research for cross-campus
projects, and the research funds are allocatedto other campuses where the project leader isaffiliated as a member of the faculty. For further
details, see the campus pages (Shin-Kawasaki
Town Campus, pages 15-16 and Tsuruoka Town
Campus, pages 17-18).

Tsuruoka Town Campus

Commissioned Research
Joint ResearchContracts
Technical GuidanceSubsidies

35%

Subsidies:
Research funds provided mainly by government andother public offices.

Amount and Number of Projects

Shin-Kawasaki
Town Campus

University Funds
Subsidies
GrantsSpecified Contributions

AmountCommissioned
Research

Definition

1. Research Funds by Campus

Amount and Number of Projects

Technical Guidance0%
University Funds
3%

Contracts

4. Subsidies not included in Imputed Income
Some of the subsidies to the university appear as imputed income of school accounts in the financial statement (¥13,272 million in FY2004. See Income and Expenditure Statement, page 33),
but others do not. The subsidies as research fund in the table above (¥6,186 million), for example, do not appear in the statement. Accordingly, corresponding expenditures are not included in theaccount under expenses for education and research. The table below describes such subsidies not included in imputed income in the financial statement.
The ¥6,186 million as the external research funds consist of the Grants-in-Aid for Scientific Research and the 21st Century COE Program (subsidies for research center development) of the
MEXT, and the Health and Labour Sciences Research Grant of the Ministry of Health, Labour and Welfare (MHLW).
In addition, direct research expenses are classified as “deposits” while indirect expenses as “miscellaneous income” in school accounts.
Thousand yen

2. Research Funds by Affiliation of Researchers

Types of Subsidies
Thousand yen

The table on the right shows the number of projects and the amount allocatedaccording to the affiliation of the researcher. In both the number of projects and theamount, the School/Graduate School of Medicine comes out on top of the list, followedby the Faculty/Graduate School of Science and Technology, and then by the Faculty ofEnvironmental Information.
0

School/Graduate School of Medicine
Faculty/Graduate School of Science and Technology
Faculty of Environmental Information
Research Institutes
Faculty of Policy Management

1,000,000 2,000,000 3,000,000 4,000,000 5,000,000

Affiliation of Researcher
Faculty/Graduate School of Letters

Number of Projects

Amount108355,517

Faculty/Graduate School of Economics

74

351,028

Faculty/Graduate School of Law

62

153,530

Faculty/Graduate School of Business
and Commerce

57

189,685

School/Graduate School of Medicine

1,568

5,018,059

Faculty/Graduate School of Scienceand Technology

513

3,080,712

Faculty of Policy Management

77

649,107

Faculty of Environmental Information

335

2,763,564

Direct Research Expenses
Amount Granted

Grants-in-Aid for Scientific Research

2,110,986

Subsidies for Joint Industry-Academia-Government Innovation
Development Projects(Research Program on Development of Innovative Technology)

08

2,110,986

031,600

191,55009%

21st Century COE Program (Research Center Development Subsidy)

0,036,000

0,036,000(0,000000

00,00000

0,036,000

000,000

010,80030%

1,675,804

1,675,800(0,000000

00,00004

1,675,804

000,000—

Subsidy for Promoting University Reform (Expense for Promoting
the Reform of Universities)—

0,103,873

0,102,673(0,000000

01,20000

0,103,873

000,000——(9,376)989

08,06512

3,926,663

031,600

202,350

59,42101

1,005,461

281,400

035,541(9,376)989

67,48614

4,932,125

313,000

237,891

30,16500

Support Program for Contemporary Educational Needs

0,015,000

60,515

Advanced Overseas Educational Research Practice Program

0,006,673

Program for Support of Development of Law and Other
Professional Schools

Graduate School of Business Administration
Faculty of Nursing and Medical Care
Keio Law School
Graduate School of Human Relations
Others57

197,765

Keio Law School

15

7,500

Research Institutes

61

903,635

Others10

124,665

Total

2,999

13,885,447

Indirect
Expense Ratio

6,865

42

Graduate School of Media and GovernanceAmount
Allocated

989

Graduate School of Human Relations

Faculty/Graduate School of Law

Commissioned toExternal
Institutions(9,376)

Faculty of Nursing and Medical Care

Faculty/Graduate School of Business and Commerce

Interest

2,112,500

Faculty/Graduate School of Letters

20

Carried
Receipts from
Forward from Other
PrecedingInstitutions
Fiscal Year

MEXT

Faculty/Graduate School of Economics

Graduate School of Business Administration

IncomeOther Income
Refund for
Removal,Transfer, etc.

Support Program for Distinctive University Education

Graduate School of Media and GovernanceIndirect Expenses
Expenditure

IncomeContribution of the MEXT Subtotal

0,031,000

0,050,000
3,926,663

3,926,973

MHLW
Health and Labour Sciences Research Grant

1,005,461

0,946,038

Total

4,932,125

4,873,011

Source: Activities and Financial Position of Keio Gijuku: FY2004 Business Report

04%

KEIO U-honbun̲E 05.11.29 7:36 PM ページ 37

5. Research Funds by Field

OthersAmountCombined

The data in this section are compiled withreference to classification of the field of
research in other official reports such as theSurvey of Research and Development by the
Ministry of Internal Affairs and Communications,and various surveys on research expenses by theJapan Association of Private Colleges andUniversities. The field of medical science comes
first in the number of projects, but science andtechnology on top in terms of amount. Research in
the field of science and technology includes
research by both Faculties of Science andTechnology and Environmental Information.

6. Ratio of Direct Research Expense to Research Funds

Amount and Number of Projects

0%

Humanities

1%

Humanities
Social Sciences
Science and Technology

3%

Dividing total research expenses into direct
and indirect expenses/general administrative
expenses, the former accounts for over 90% of
the total while the latter account for the rest at
Keio. The universities in Japan are typicallyallowed to allocate up to 30% of the direct
research expenses from the governmental
competitive research funds they receive as
indirect expenses, but in overall terms, theactual percentage is extremely low, for example,
compared with that of North American andEuropean counterparts.

Medical Science
Combined
OthersSocial Sciences

12%
AmountMedical Science

37%
Science andTechnology

47%

37

Number of
Projects
0

20

40

60

80

AmountGeneral Administrative Expenses
Indirect
Expenses

6%

2%

Direct Research Expenses
Indirect Expenses
General Administrative Expenses

100

38

Direct Research Expenses

Thousand yen

Field

Number of Projects

AmountHumanities

181

434,446

Social Sciences

301

1,677,600

Science and Technology

825

6,484,236

Medical Science

1,638

5,093,026

53

193,839

Combined
Others

1

2,300

Total

2,999

13,885,447

Field

Indirect Expenses

General Administrative Expenses

Research Funds at Keio University in FY2004

Keio University Annual Report on Research Activities 2004–2005

92%
Definition
Thousand yen

Indirect Expenses:
Expenses provided equivalent to a certain percentage ofthe competitive research funds in addition to thedirect expenses for the research to supplementadministrative and operational costs of the institution towhich a researcher is affiliated.

Total Research Expenses
13,885,447

General Administrative Expenses:
Expenses provided to supplement administrative costs forresearch other than direct expenses for the research.

Direct Research
Expenses

Indirect Research
Expenses

General Administrative
Expenses

12,754,240

321,228

809,979

Indirect Expenses and General Administrative Expenses
Thousand yen

600,000

General Administrative
Expenses
Indirect Expenses

500,000

Humanities

9,774

483

Social Sciences

53,17567,663

Science and Technology

134,460

434,603

Medical Science

119,730

288,352

4,089

18,5330345

Combined

400,000

OthersTotal

321,228

809,979

300,000
Definition

200,000

Shown in the graphs and a table on theright is a breakdown by campus of direct
research expenses, indirect expenses, and generaladministrative expenses. The Shinanomachi
Campus and the Shonan Fujisawa Campus are
first and second respectively, in the amount of
direct research expenses and general administrative expenses, while the Shinanomachi
Campus and Yagami Campus are first and secondin direct expenses.

Direct Research Expenses

Shin-Kawasaki
Town Campus

0.2%

Tsuruoka Town Campus

Social Sciences:
Economics, Sociology, Business and Commerce, Political Science, Law, and other social sciences.

Indirect Expenses

Shin-Kawasaki
Town Campus

3.2%

0%

Mita Campus
Shonan Fujisawa
Campus

1.7%

14.0%

Shin-Kawasaki
Town Campus

Tsuruoka Town Campus
Hiyoshi Campus

0.6%

SocialSciences

Science Medical
andScienceTechnology

Combined

OthersHiyoshi Campus

0.9%

Shonan Fujisawa
CampusMita Campus

Mita Campus

10.8%

11.9%
Shonan Fujisawa
CampusYagami Campus

16.6%

33.2%

Yagami Campus

22.1%

Yagami Campus

33.5%
Shinanomachi Campus

37.0%

Shinanomachi Campus

36.3%

Shinanomachi Campus

35.3%

Science and Technology:
Applied Chemistry, Chemistry, Mechanics and Shipbuilding, Engineering, Mathematics, Electrics,
Communications, Physics, and other science and technology.

Humanities

Tsuruoka Town Campus

2.6%

0.6%
17.0%

22.5%

General Administrative
Expenses

0%

Hiyoshi Campus

Humanities:
History, Philosophy, Literature, Languages, and other humanities.

100,000

0

7. Direct Research, Indirect, and General Administrative Expenses by Campus

Mita Campus

Medical Science:
Medicine, Nursing, Pharmaceutical Science, and other health and medical sciences.

Hiyoshi Campus

Yagami Campus

Shinanomachi Campus

Shin-Kawasaki Town Campus

Shonan Fujisawa Campus

Combined:
Interdisciplinary fields.

Tsuruoka Town Campus

Thousand yen

CampusDirect Research Expenses

Indirect Expenses

General Administrative Expenses

Mita Campus

1,789,794

38,33487,673

Hiyoshi Campus

211,447

2,058

7,230

Yagami Campus

2,818,981

107,892

134,739

Shinanomachi Campus

4,624,819

118,620

285,580

Shonan Fujisawa Campus

2,875,840

54,324

268,714Shin-Kawasaki Town Campus

27,6750

4,825Tsuruoka Town Campus

405,684

021,21812,754,240

321,228

809,979

Total

KEIO U-honbun̲E 05.11.29 7:36 PM ページ 39

Competitive Research Funds

39

2 Basic Research Programs

1 Grants-in-Aid for Scientific Research (Kakenhi)
Kakenhi is designed to remarkably develop any academic research, from basic toapplied, in fields ranging from humanities and social sciences to the natural sciences,
based on the free thinking of individual researchers. The grants are meant to be provided, after
peer review, to innovative and pioneering research projects. In FY2004, the Kakenhi were
granted for approximately 49,000 research subjects out of total 113,000 applications.
The table shows the number of Kakenhi projects adopted (new and those continuing fromthe previous year) and the amounts distributed (at the time of selection, different from the dataon page 36) of the top 20 institutions from FY2002 to FY2004. The aggregate of the top 10
accounts for about 50% of the total, and that of the top 20 for about 60%. Keio University was
ranked 11th overall and first among private universities, with the amount distributed
equivalent to 1-2% of the total.

The selected researchers perform the research at their own facilities. This type includes
both group research (team-research, called CREST-type) and individual research (called
PRESTO-type).
In the Supervisor-Oriented type, in contrast with the Proposal-Oriented type, thesupervisor directly organizes and intimately supervises his/her own research team. It consistsof two programs: ERATO, discovering and breeding seeds for technological innovation, andICORP, creating seeds of innovative science and technology by coordinating outstanding
research capabilities and potential between Japan and a foreign country.

Affiliation of Research Supervisors in the Basic Research Programs
National
Universities

Number of people

PublicUniversities

Independent
Administrative
Corporations

PrivateUniversities

Others*1

Total

Proposal-Oriented Type Research
CREST (team-type)

0011

0001

00004

0001

006

023

PRESTO (individual-type)

0005

0002

00005

0006

002

020

Source: JST, http://www.jst.go.jp/kisoken/en/index.html
The research areas and subjects selected in the table include
those in progress from FY2002 to FY2004. The affiliations ofresearch supervisors as of 1 July 2005.

013*1 Others include institutions such as national research institutes,
companies, foundations, overseas research institutes, etc.

Supervisor-Oriented Type Research
ERATO

0010

0000

00001

0001

001

ICORP

0004

0000

00000

0000

000

004

Continuing Research*2

0053

0001

00004

0004

007

069

Total

0083

0004

00014

0012

016

129

Research Representatives and Subjects of Keio University in CREST
Professor Masahiko Inakage
Faculty of Environmental Information/Graduate School of Media and Governance
Professor Masaru Tomita
Director, Institute for Advanced Biosciences (IAB)/Faculty of Environmental Information
Professor Atsushi Nakajima
Faculty of Science and Technology
Professor Koji Suzuki
Faculty of Science and Technology
Professor Kimihisa Yamamoto
Faculty of Science and Technology
Professor Hideyuki Okano
School of Medicine
Professor Shigeo Koyasu

School of Medicine

Associate Professor Kohei Ito

Faculty of Science and Technology*2 Continuing Research refers to the Solution Oriented Research
for Science and Technology (SORST) program to continue theresearch (ex. extending the research period) for basic research
program for its excellence and potential.

The Research of Ubiquitous Content Production Authoring System
Establishment of Modeling Simulation Environment for Systems Biology
Nano-scale Design Oriented Towards Optomagneto Materials
Creation of “Nanochemical Probes” and their Biomedical Sensing Application
Creation of Macromolecules with Precise Metal Assembly for Nano-catalysts
Studies on the Development and Regeneration of Central Nervous System Basedon the Stem Cell System
Infectious Disease Control by Understanding the Strategy of Pathogenic Microbes
Affecting Host Immune System
Development of All-silicon Quantum Computers

3 Special Coordination Fund for Promoting Science and Technology
Kakenhi Distributed by Institution
FY2002
Rank

Institution

FY2003

FY2004

Number of
Projects

Amount(Million yen)

Institution

Number of
Projects

Amount(Million yen)

Institution

Number of
Projects

Amount(Million yen)

01

University of Tokyo

2,610

018,568

University of Tokyo

2,501

018,751

University of Tokyo

2,676

022,101

02

Kyoto University

1,881

009,448

Kyoto University

1,820

009,370

Kyoto University

2,031

012,24403

Osaka University

1,531

007,169

Osaka University

1,484

007,487

Osaka University

1,592

009,24304

Tohoku University

1,571

006,905

Tohoku University

1,542

006,889

Tohoku University

1,599

008,475

05

Nagoya University

1,045

005,248

Nagoya University

1,008

005,474

Nagoya University

1,079

006,722

06

Hokkaido University

1,138

004,738

Hokkaido University

1,103

004,920

Kyushu University

1,287

005,415

07

Kyushu University

1,271

004,511

Kyushu University

1,202

004,535

Hokkaido University

1,183

005,347

08

Tokyo Institute ofTechnology

722

003,654

Tokyo Institute ofTechnology,705

004,008

Tokyo Institute ofTechnology

09

University of Tsukuba,684

002,445

University of Tsukuba

709

002,530

10

Hiroshima University,789

002,058

Hiroshima University

753

002,130

11

Keio University543

002,003

Keio University

539

12

Kobe University

562

001,825

Kobe University

13

Chiba University453

001,698

RIKEN

14

Okazaki National
Research Institutes

194

001,648

15

Tokyo Medical and
Dental University383

001,583

16

National Institute of
Genetics

64

001,443

17

Okayama University

553

18

Kumamoto University

19
20

757

004,160

University of Tsukuba

741

002,611

Hiroshima University

842

002,403

001,961

Keio University578

002,227558

001,735

Kobe University

669

002,216381

001,609

RIKEN

437

002,149

Okazaki National
Research Institutes

175

001,566

Chiba University

538

001,858

Okayama University563

001,501

Okayama University

608

001,695

Chiba University

467

001,378

Tokyo Medical and
Dental University364

001,423

Tokyo Medical and
Dental University

360

001,354

Waseda University354

001,288

National Institute of
Genetics

60

001,311

RIKEN

,323

001,217

Kumamoto University

340

Niigata University,418

001,089

Kanazawa University

419

001,494

Research in Progress
Research Representative
Professor Keiichi Fukuda

Affiliation
School of Medicine

460

001,422

Professor Jun Murai

Faculty of Environmental Information

National Institute of
Genetics

71

001,422001,168

Kumamoto University

348

001,241

001,137

Tokyo Metropolitan
University

266

001,151

Professor Hideyuki Tokuda
Associate Professor Kotaro Oka
Professor Shinji Ozawa
Professor Kazuo Umezawa
Professor Yuichiro Anzai

Faculty of Environment Information
Faculty of Science and Technology
Faculty of Science and Technology
Faculty of Science and Technology
Faculty of Science and Technology

124,634

126,341

155,051B

064,744066,094

078,721B/A

00052%

00052%

00051%

C079,961

080,814095,596

C/A

00064%

00064%

00062%

B: Total of top 10 institutions

C: Total of top 20 institutions

Source: JSPS, http://www.jsps.go.jp/j-grantsinaid/
Data here is classified by the research institution with which the research representative is affiliated.

FY2004 Special Coordination Fund for Promotion of Science and Technology
Top Ten Universities by Amount of Funds Commissioned
100 million yen

Rank

University

Accumulated Amountfor Research in
Progress up to FY2003

Newly Commissioned Total
Research in FY2004

01

University of Tokyo

036.3

11.5

047.8

02

Kyoto University

020.2

02.9

023.1

03

Osaka University

018.1

03.2

021.3

04

Tohoku University

016.1

03.1

019.2

05

Keio University

005.1

09.8

014.9

06

Kyushu University

007.5

07.2

014.7

07

Waseda University

003.7

10.8

014.5

08

Hokkaido University 010.3

01.2

011.5

09

Tokyo Institute ofTechnology

02.7

01.1

003.8

University of Tsukuba 002.4

00.6

003.0

51.4

173.8

10

Total of Top 10 Institutions

0

122.4

Source: Office of the Special Coordination Fund for Promotion of Science and Technology, MEXT

Source: Japan Science and Technology Agency 2004, Second Edition

A

A: Total amount distributed (research expenses)

The Special Coordination Fund for Promoting Science and Technology is a budget for
coordination for implementing important matters that are essential for science and technology
promotion in accordance with the Council for Science and Technology Policy. The funds are
utilized for measures that have a high capacity as policy catalysts, such as those that set
precedents for other ministries, those that are intended for borderline or integrated projects thatany one ministry or agency cannot handle alone, those that are expected to generate asynergistic effect through multi-institutional collaboration, or those that should be tackled
promptly and actively. The areas of these measures are as follows:
1) Reform of science and technology systems in order to create excellent results and utilize
them effectively2) Strategic measures focusing on fields and domains which are expected to be promising
3) Promotion of internationalization of scientific and technological activities
Specifically, the programs under the fund include: Support for establishing organizations
for competitive research funding, Promotion of research activities tackling the key issues, etc.,
Effective promotion of joint research with industries, academia, and government,
Encouraging development of strategic research centers, Fostering talent in emergent
research fields, Urgent researches, Leadership for international scientific cooperation,
Promotion of pioneering researches, etc., Basic survey on science and technology promotions,Supporting young researchers with fixed-term appointments, and Proposal for scienceand tech in science and technology policy.

Program
Effective promotion of joint research with industries,
academia, and government
Effective promotion of joint research with industries,
academia, and government
Promotion of pioneering researches, etc
Fostering talent in emergent research fields
Fostering talent in emergent research fields
Comprehensive Researches
Comprehensive Researches

Research Subject
Regeneration of Cardiomyocytes Using Stem Cell Biology and Tissue Engineering
Research on IPv6 Protocol Stack with Low Power Consume for Mobile Terminals
Research on Ubiquitous Information Society Based on Trans-disciplinary Science
Training Program for System Biologists in Keio University
Highly Dependable Software for Capturing Environmental Information
Development of the Artificial Control Method of Blood Vessel Wall Functions
A Study on Fundamental Technology of Distributed Real-time Network for
Human Activity

Research Commissioned in FY2004
Research Representative
Affiliation
Professor Fumio Teraoka
Faculty of Science and Technology
Professor Hiroshi Yanagawa
Faculty of Science and Technology

Program
Promotion of research activities tackling the key issues
Effective promotion of joint research with industries,

Director Yuichiro Anzai

Encouraging development of strategic research centers

Research Subject
Development of Analyzing and Sharing System of Information Security
Development of Automation System for Selection of Antibody
academia, and government
Research Institute for Digital Media and Content (DMC)

Fostering talent in emergent research fields

Training Course for Technical Assistants on in vivo Medical Science

Professor Sadakazu Aiso

Research Institute for Digital Media andContent (DMC)
School of Medicine

40Competitive Research Funds

Keio University Annual Report on Research Activities 2004–2005

The competitive research fund has been defined as a “fund for research and development to be distributed to researchers and institutions making proposals
on a subject publicly announced and passing the examination based primarily on scientific and technological perspectives, by a committee composed of morethan two members including experts in the subject field,” (Reform of the Competitive Research Funding System, Council for Science and Technology Policy, April
2003). In its “Science and Technology Basic Plan FY2001-FY2005,” the Japanese government set a target for doubling the budget appropriation for competitive
research funds after the model of the United States, which holds an established position in world-leading research supported by such funds.
Amount of competitive funds and adopted rate can be indicators for the research potential of universities. National universities have long been aheadof private universities in part due to different research environments. The national universities have been better funded with government subsidies foradministration and maintenance of facilities, so in comparison they have better research facilities than their private counterparts. Well-equipped researchfacilities are a great advantage in generating high-quality research and then attaining competitive funds.
However, this situation is expected to change as the national universities have been converted into independent corporations since FY2004.
Competition for funding between universities will certainly grow more intense, though there are no perceptible changes yet.
The government budgeted ¥360.6 billion for competitive research funds in FY2004, approximately one-tenth of total allocations for science andtechnology. Grants-in-Aid for Scientific Research (Kakenhi) funded by the Ministry of Education, Culture, Sports, Science and Technology (MEXT) andthe Japan Society for the Promotion of Science (JSPS) accounted for the largest amount of all at ¥183 billion, up by ¥6.5 billion or 3.7% year-on-year. Thiswas followed by ¥46.3 billion for the Basic Research Programs through MEXT and the Japan Science and Technology Agency (JST), ¥37.9 billion for the
Health and Labour Sciences Research Grant through the Ministry of Health, Labour and Welfare (MHLW), and ¥38.6 billion for the Special
Coordination Fund for Promotion of Science and Technology thorough MEXT and JST, respectively.
The following is an overview of representative competitive research funds of MEXT: 1) Kakenhi, 2) Basic Research Programs, and 3) Special
Coordination Funds for Promoting Science and Technology. A portion of the achievements by Keio University will also be introduced here.

The Basic Research Programs of JST promote purpose-oriented basic research for the
strategic objectives of the national government, with the mission of meeting not only social andeconomic demands but also national policies for science and technology. The specific areas ofresearch are presented by the JST in strategic sectors formulated by MEXT. The JST calls for proposals from each of the research areas within the sectors and designates research supervisors.
The Basic Research Programs consist of two types: Proposal-Oriented and SupervisorOriented. In the Proposal-Oriented type, a supervisor widely seeks application proposals
from public and private universities and research institutes, reviews and selects the applications.

KEIO U-honbun̲E 05.11.29 7:36 PM ページ 41

Researchers at Keio University in FY2004

Researchers from outside KeioThis section presents data on researchers involved in research or education at Keio University (Professors, Associate Professors, Assistant Professors
and Instructors), doctoral students and awardees of doctor’s degrees, and researchers participating in research projects at Keio but not affiliated under
the any of above conditions.

Keio University has long emphasized the creation of a good environment for intellectual exchange and synergistic cooperation with researchers both within and outside the institution, withthe goal of sharing common or related research subject.
Not only undergraduate faculty/graduate school but research institutes of Keio University accept researchers from other research institutions and universities outside Keio.

Number of Researchers Accepted—Breakdown by Job Title and Status
Job Title/Status of Researchers

Number of Researchers

41

0,039

Researchers of Keio Leading-edge Laboratory of Science andTechnology (KLL) (Yagami)

0,071

Researchers employed by research, educational, or medical institutions other than the
School of Medicine of Keio University.

Senior Visiting Researchers, Keio Research Institute at SFC (Shonan Fujisawa),209

Researchers accepted by Keio Research Institute at SFC upon application from an institution
not affiliated with Keio University, or that from the applicant him/herself.
Applicants must have a master’s degree or qualified as equivalent having experienceand achievements as an independent researcher.

Visiting Researchers, Keio Research Institute at SFC (Shonan Fujisawa)

125

Researchers accepted by Keio Research Institute at SFC upon application from an institution
not affiliated with Keio University or from the applicant him/herself. Applicants musthave a bachelor’s degree or qualified as equivalent having experience and achievements
as an independent researcher.

0,255

Special Research Professors

Total

Mita Campus

0,355

00036

00012

0,403

Hiyoshi Campus

0,292

00018

00001

0,311

Yagami Campus

0,239

00018

00034

0,291

Visiting Professors and Researchers *1 (See Table A)

0,568

Others (See Table B)

1,123
1,903

00005

00075

Researchers participating in research under a commissioned research contract.

School of Medicine Researcher (Shinanomachi)

Researchers with Fixed Period Contract

0,488

Researchers participating in research without a contract of commissioned research.

81
0,0Tenured Researchers

Shinanomachi Campus

Qualifications

Shonan Fujisawa Campus

0,123

00043

00078

0,244

Total

Total

1,497

00120

00200

1,817

Place names in parentheses indicate affiliated campus.

As of 1 May 2004

Table A: Visiting Professors and Researchers
Job Title, Status/Campus

Support for Future Researchers
There are two types of doctor’s degrees: course and dissertation doctorates. Course doctorates are conferred upon completion of course work with all other requirements. Dissertation
doctorates are conferred on those who have submitted a dissertation with consent of a committee of a graduate school, and passed the examination by a board of review.
The standard period for completion of a doctoral course is three years, except for the Graduate School of Medicine, which maintains a four year standard.

Number of Doctorates Awarded

Number of Students Registered in Doctoral Courses

Course Doctorate

Mita/Hiyoshi

YagamiShinanomachi

Shonan Fujisawa

Visiting Professor

0019

24

012

0001

056

Visiting Associate Professor

0013

10

009

0000

032

Visiting Lecturer

0004

10

015

0000

029

Visiting Research Fellow

0033

42

053

0000

128

Visiting Research Associate

0002

07

001

0000

010

Total

0071

93

090

0001

255

Graduate School of Letters

<045>

121

Graduate School of Letters

003

Graduate School of Economics

<015>

073

Table B: Others

Graduate School of Economics

002

Graduate School of Law

<030>

110

Research Institute

Graduate School of Law

005

Graduate School of Human Relations

<011>

045

Institute of Cultural and Linguistic Studies (Mita)

Graduate School of Human Relations

010

Graduate School of Business and Commerce

<020>

051

Graduate School of Business and Commerce

004

Graduate School of Medicine *1

<068>

168

Graduate School of Medicine

026

Graduate School of Science and Technology<150>

Graduate School of Science and Technology

091

Graduate School of Business Administration

Graduate School of Business Administration000

Graduate School of Media and Governance

Graduate School of Media and Governance019

As of 1 May 2004

Subtotal

160

Figures in parentheses indicate the maximum number of entrants for the graduate school.

No. of Researchers at Keio University*2

No. of Researchers not Employed by Keio

Total

041

055

0,096

Institute for Media and Communications Research (Mita)

0v8

062

0,070

Keio Economic Observatory (Mita)

037

030

0,067

373

Shido Bunko, Institute of Oriental Classics (Mita)

009

002

0,011

<008>

013

International Center (Mita)

046

025

0,071

<030>

173

Teacher Training Center (Mita)

045

041

0,086

Fukuzawa Memorial Center for Modern Japanese Studies (Mita)

025

036

0,061

Institute of East Asian Studies (Mita)

022

031

0,053

Center for Japanese Studies (Mita)

011

031

0,042

Research Center for the Arts and Arts Administration (Mita)

021

015

0,036

*1 The figure for the Graduate School of Medicine refers to the number of students registered in doctoral
courses.

Dissertation Doctorate

Total

Graduate School of Letters

008

Global Security Research Institute (G-SEC) (Mita)

022

005

0,027

Graduate School of Economics

002

Research Institute for Digital Media and Content (DMC) (Mita)

077

036

0,113

Graduate School of Law

003

Institute of Physical Education (Hiyoshi)

020

041

0,061

Graduate School of Human Relations

004

Health Center (Hiyoshi)

022

002

0,024

Graduate School of Business and Commerce005

Keio Research Center for Foreign Language Education (Hiyoshi)

050

019

0,069

Graduate School of Medicine

112

Sports Medicine Research Center (Hiyoshi)

011

006

0,017

Graduate School of Science and Technology

011

Keio Research Center for the Liberal Arts (Hiyoshi)

172

047

0,219

Graduate School of Business Administration

000

Total

639

484

1,123

Graduate School of Media and Governance004

Subtotal

149

Total
As of 31 March 2005

309

Figures show the totals for FY2004. Place names in parentheses indicate location of the institution.
*1 Generic designation used for visiting professor, visiting associate professor, visiting lecturer, visiting research fellow and visiting research associate. (Excludes researchers at Keio listed in Table B).
*2 Researchers at Keio University: the figure indicates total number of researchers including teachers in the affiliated elementary and secondary schools of Keio, in addition to tenured and non-tenured researchers ofundergraduate faculties/graduate schools or research institutes. A researcher affiliated to more than two institutions is counted as one researcher of each.

42
Researchers at Keio University in FY2004

Keio University Annual Report on Research Activities 2004–2005“Tenured researchers” are those employed under full-time contracts without fixed terms. “Researchers with fixed period contract” are either full-time or part-time. Of those with fixed period
contracts, “special research professors” are paid by research funds allocated from outside Keio University as a condition of appointment.
“Researchers” in the following data only include University researchers (Professors, Associate Professors, Assistant Professors and Instructors) and excludes teachers at affiliated elementaryand secondary schools of Keio University.
In contrast to Mita and Hiyoshi campuses, there are more researchers funded by external research sources at the Yagami, Shinanomachi, and Shonan Fujisawa campuses. The number of the
non-tenured researchers (that is, the total number of researchers with fixed period contracts and special research professors) accounts for 17% overall, but is a striking 49% at Shonan Fujisawa Campus.

CampusNumber of Researchers

Research Associates of Faculty of Science and Technology (Yagami)

KEIO U-honbun̲E 05.11.29 7:36 PM ページ 43

Technology Transfer(1) Number of New Licensing Agreements

Thousand yen

50

Research needs
Research funds
Joint/commissioned
research

Patenting
Licensing
Support for businessstartups

Research
at Keio

Assessment
Commercialization

Intellectual
Property Center Society
(IPC)

Keio

(2) Licensing Revenues

43

1 Rules and Regulations for Intellectual Property and Technology Transfer

40

34

42,01240,00020
20

30,00010
10

16,62820,0005

10,000

0
1999

2000

59,53860,00050,00026

30

63,949

2001

2002

2003

2,731

0

2004

1999
(3) Startups and Products Created Using IP Rights Owned by Keio
The number of startups based on IP rights owned by Keio has
steadily increased, with two companies in FY2001, one in FY2002, four in
FY2003, and three in FY2004.
The number of products newly developed from Keio’s IP rights hasreached to approximately 30 to date.

11,189

2000

2001

2002

2003

2004

(4) External Research Funds Acquired Based on IP Rights Owned by Keio

600,000

Thousand yen

552,974

438,787

500,000
355,088

400,000
300,000

In FY2004, the Guidelines for Intellectual Property was enacted. It formed the basis for activities dealing with intellectual property and technology
transfer at Keio and clarified the organizational support of the university as a whole for these activities, with new or revision of the existing rules concerning inventions as follows.
“Rules and Regulations for Inventions” (revised)“Rules and Regulations for Tangible Achievements of Research” (new)“Rules and Regulations for Intellectual Property Mediation Committee” (new)200,000
100,000
0
2002

2003

2004

The above external research funds are included in research funds of each campus indicated in page 35.

2 Intellectual Property
Filing activities of the IPC remained active throughout FY2004 as in the previous year. The IPC filed 157 domestic patent applications, 40 PCT applications, and 58 international patent applications. Noteworthy is the fact that the number of international patents increased.
The following charts and a graph show patent applications by field of technology, campus, and inventor.
(1) Patent Applications

180
PCT

International(2) Proportion of Applications by Field ofTechnology

166

Domestic

157

160
140

122

120

44%

Information/Communications

25%

Control/Measurement

25%

Materials/Chemicals

6%(3) Number of Applications by Campus

100

83

80
62

58

60
41

38

40
20

Bio/Medical

40

30
11

2

7 7

10 11

16

1999

2000

2001

355

Shinanomachi (School of Medicine)

189

SFC

94

Hiyoshi

5

Mita

4

(4) Number of Inventors by Category

7

0
1998

Yagami (Faculty of Science and Technology)

2002

2003

2004

Professor

102

Associate Professor

47

Lecturer

51

Instructor/Assistant84

Student

285

Staff Member, Other

33

3 Technology Transfer
Technology transfer of the intellectual properties representing technologies of the university is engaged through:(1) Licensing to a company;(2) Starting a company based on intellectual property (IP) rights; and(3) Joint research with a company towards commercialization.
The following graphs indicate technology transfer by the above categories.

4 Platform for Information Exchange between Industry and Academia
The IPC strongly believes, from six years of experience in implementing IP and technology transfer activities, the importance to further
activate industry-academia collaboration through informationexchange and integration of knowledge between the two. Thus, the IPC
has started Keio Innovation Network. It is a monthly meeting on specific topics to convey technological information at Keio. The first meeting
was held in February 2005, with an overview as shown below.

The 1st Keio Innovation Network (East Building, Mita Campus)“Visible Light Communications”
Prof. Masao Nakagawa, Faculty of Science and Technology“Synthesis and Application of Transparent Nano-phosphors”
Assc. Prof. Tetsuhiko Isobe, Faculty of Science and Technology“Optical Waveguide for Photonic Networks”
Assc. Prof. Hiroyuki Tsuda, Faculty of Science and Technology“Magnetic Memories Based on Domain-wall Motion”
Instructor Eiji Saitoh, Faculty of Science and Technology

5 Others(1) 5th Intellectual Property Center Award
Every year, the IPC awards Keio researchers who generated intellectual property,
transferred it to society, and made a significant contribution to the activities of the IPC. The
winner for FY2004 was Dr. Masataka Kuwana of the School of Medicine, for his patent for“Diagnosis for Scleroderma.”(2) The Award of the Minister Bestowed to the IPC Twice in Succession forDistinguished Service for Industry-Academia-Government Collaboration
The Keio researchers and the director of the IPC who were bestowed the Award of the
Minister of State for Science and Technology Policy on “Development and Practical
Application of Techniques for the Analysis of Metabolome” in June 2004, at the Council ofIndustry-Academia-Government Collaboration Promotion in Kyoto are as follows:
Tomoyoshi Soga, Associate Professor, Faculty of Environmental Information
Masaru Tomita, Director, Institute for Advanced Biosciences
Keisuke Shimizu, Director, Intellectual Property Center
This was the second consecutive win for the IPC which received the Award of the
Minister of Education, Culture, Sport, Science and Technology in June 2003.

Presentation Ceremony of the 5th Intellectual Property Center Award

44
Technology Transfer

Keio University Annual Report on Research Activities 2004–2005

New research needs
Loyalties

Researchachievements

The Intellectual Property Center (IPC)
was established in November 1998. As
depicted in the diagram on the left, the role ofthe IPC is to act as a linking hub between
Keio and society at large. This role involves
protecting research achievements at Keio as
intellectual properties, transferring thepatents to society, giving feedback of themarket evaluations to the researchers, andultimately stimulating research activities at
the university. The IPC believes that, throughsuch activities, it has been contributing to therealization of “creating intellectual values,”“exploring entrepreneurial potential,” and“inspiring education.”

70,00044

KEIO U-honbun̲E 05.11.29 7:36 PM ページ 45

Awards for Research Activities, FY2004

Date Awarded(DD/MM/YY)

WinnerAward

Reason for Award

Awarding Institution

22/09/04

Yasuo Suga
(Prof., Fac. of Science andTechnology) et al.

The International
Conference SCIS & ISIS
2004 Best Paper Award

For the best paper from among the more than 300 submitted
to the International Conference SCIS and ISIS 2004.

SCIS & ISIS 2004
Organizing
Committee

22/09/04

Kazunobu Sawamoto(Asst. Prof., Sch. of Medicine)

FY2004 Japan Neuroscience
Society Encouragement
Award

For development of technology for visualization, separation,and transplantation of central nervous system precursor cells
and analysis of biological properties.

Japan Neuroscience
Society

29/09/04

Shigeru Tanaka(Prof., Fac. of Science andTechnology)

UBS Innovation Award,
Special Award

For “High-Performance Indoor Air Pollutant Cleaning
Technology for Creating Comfortable Environments,” work
highly-regarded for increasing the potential of this technology
for application in new businesses.

UBS Securities
Japan Ltd.

01/10/04

Hideyuki Tokuda(Chairman, Grad. Sch. ofMedia and Governance/
Prof., Fac. of Environmental
Information)

FY2004 Individual
Commendation forContribution to thePromotion of Information
Technology (Commendationof the Minister of Economy,
Trade and Industry)

For best effort toward realization of a ubiquitous network
society through dissemination of achievements of ubiquitous
computing research; for contributions relating to therecruitment and development of highly-competent software
personnel; and for other contributions toward expanded useof information technology in Japan.

Ministry of
Economy, Trade andIndustry

01/10/04

Yoshiyasu Takefuji(Prof., Fac. of Environmental
Information)

1st JICA President’s
Commendation

For best effort in JICA international cooperation projects
concerning human resource and community development indeveloping countries through long-term contributions andcooperation in technical guidance in the IT field, particularly
in security.

Japan International
Cooperation
Association (JICA)

03/10/04

Hideyuki Okano(Prof., Sch. of Medicine)Distinguished Scientists
Award, Faculty of
Pharmaceutical Science,
Catania University, Italy

For his pioneeristic studies on the self-replicating
mechanisms of neural stem cells and the regeneration ofcentral nervous systems.

Faculty of
Pharmaceutical
Science, Catania
University, Italy

10/10/04

Takanori Hattori(Instr., Fac. of Science andTechnology)

The Japan Society of High
Pressure Science andTechnology Encouragement
Award

For development of equipment technology in high-pressure
experiments using synchrotron radiation; for efforts toincrease the precision of measurement results; and forquantitative arguments based on highly-quality data.

The Japan Society ofHigh Pressure
Science andTechnology

23/10/04

Naoyuki Yoshino(Prof., Fac. of Economics)

Conferment of Honorary
Doctorate of Göteborg
University, Sweden

For distinguished achievements in the theory and analysis of
fiscal and monetary policy and for major contributions toimproving the exchange program between Keio University and
Göteborg University.

Göteborg University,
Sweden01/11/04

Hideyuki Okano(Prof., Sch. of Medicine)Japan Medical Association(JMA) Award for Medicine

For research achievements regarding “the identification ofneural stem cells in the adult brain and central nervous
system regeneration medical science,” which linked theachievements of basic research concerning neuralregeneration based on neural stem cells to central nervous
system regeneration medical science.

JMA

02/11/04

Yasuaki Einaga(Assc. Prof., Fac. of Scienceand Technology)

The JapanesePhotochemistry Association(JPA) Young Scientist
Award

For achievement on “design and characterization of photocontrollable composite magnetic materials.”

JPA

05/11/04

Kouhei Ohnishi(Prof., Fac. of Science andTechnology)

The IEEE Industrial
Electronics Society Dr.-Ing.
Eugene Mittelmann
Achievement Award

For outstanding contributions to the development of motion
control and first realization of haptic sensation for robotic
forceps.

IEEE

09/11/04

Yoshikazu Kenjyou(Prof., Fac. of Business andCommerce)

The 27th Annual Award for
Research Monographs on
Labour, 2004

For the publication, Nenkin Kaikaku to Sekkyokuteki Shakai
Hosho Seisaku—Saihaibun Seisaku no Seiji-keizaigaku(Pension Reform and Positive Social Security Measures:
Politics and Economics of Reallocation Policies), Keio
University Press, (Mar. 2004).

The Japan Institutefor Labour Policy andTraining/Yomiuri
Shimbun20/11/04

Goro Suzuki(Prof., Fac. of Economics)

Rotary Foundation District
Service Award

For important contributions to the development of scholarshipstudents as chairman of the Rotary Foundation Alumni
Association.

Rotary Foundation

22/11/04

Masao Nakagawa(Prof., Fac. of Science andTechnology)

Ericsson
Telecommunications Award
2004

For the contribution of “High-level Mobile Communications
Technology” to increasing the sophistication of CDMA, ITS,
wireless Homelink, and visible light communications
technology from the latter half of the 1970s to the present.

Nippon Ericsson K.K.

Source: Jukuho (Keio Biweekly Newsletter) No.2055–2080 (April 2004–March 2005)

45

Date Awarded(DD/MM/YY)

WinnerAward

Reason for Award

Awarding Institution

15/04/04

Nobuyoshi Shimizu(Prof., Sch. of Medicine)Award of the Minister of
Education, Culture, Sports,
Science and Technology(for Achievement in Research)

For discovering disease-causing genes through decoding of
human genomes, and for research into DNA diagnostic
methods.

Minister of
Education, Culture,
Sports, Science andTechnology (MEXT)

15/04/04

Hideyuki Okano(Prof., Sch. of Medicine)Tokyo Techno-Forum 21
Gold Medal Award

For a series of research endeavors into neural stem cells:“Identification of neural stem cells in the adult brain andresearch on regeneration of the central nervous system using
these cells.” This research promises to yield revolutionary
brain disease treatment techniques which could restore brain
functioning through the regeneration of lost neural cells.

Tokyo Techno-Forum
21

Hiroto Izumi(Sp. Rsch. Prof., Fac. of
Science and Technology)

Japan Association for Real
Estate Sciences (JARES)
Authorship Award

For authorship of Urban Planning through Relaxation of Floor
Area Ratio (FAR) Regulations, Shinzansha Publisher Co., Ltd.
(Mar. 2002), which presents the history of the system ofurban planning through relaxation of FAR regulations and ananalysis of the basis for relaxation.

JARES

21/05/04

Yoshiyuki Matsuoka(Prof., Fac. of Science andTechnology),
Masato Inoue(Instr., Fac. of Science andTechnology)

FY2003 Japan Society for
Design Engineering (JSDE)Best Paper Award

For the thesis “System for Obtaining Diverse Design Solutions
Based on Emergence.” Journal of Japan Society for Design
Engineering (in Japanese), Vol. 38, No. 8, 411-420, (2003).

JSDE

25/05/04

Hiroto Izumi(Sp. Rsch. Prof., Fac. of
Science and Technology)

2004 Association of Urban
Housing Sciences(Authorship Award)

For authorship of Urban Planning through Relaxation of FAR
Regulations, Shinzansha Publisher Co., Ltd. (Mar. 2002),
which presents a quantitative analysis of the effect on land
prices of relaxing FAR regulations.

Association of Urban
Housing Sciences

31/05/04

Shuzo Murakami(Prof., Fac. of Science andTechnology)

FY2003 Japan Association
for Wind Engineering(JAWE) Association Award(for Achievement)

For establishing the field of computational wind engineering,systematization of wind environment engineering andcontributions to the activities of the JAWE.

JAWE

Hirokazu Kono
(Prof., Grad. Sch. ofBusiness Administration)
et al.

33rd Japan Institute ofIndustrial Engineering (JIIE)
Literature Award(Contribution Award)

For research notes presented in the IE Review, Vol. 44, No. 4,
Dec. 2003 “A Study for Vitalizing Domestic Manufacturing inJapan—From the Perspective of Shop Floor Improvement
Activities—.”

JIIE

Tomoyoshi Soga
(Assc. Prof., Fac. ofEnvironmental Information),
Masaru Tomita(Dir., Institute for Advanced
Biosciences/Prof., Fac. ofEnvironmental Information),
Keisuke Shimizu(Dir., Intellectual Property
Center)Industry-AcademiaGovernment Collaborative
Distinguished Service
Commendation(Award of the Minister ofState for Science andTechnology Policy)

For development and practical application of techniques forthe analysis of metabolome.

Minister of State for
Science andTechnology Policy

28/08/04

Shoji Kasai(Prof. Emer.)

1st Japan Boki Association
Award

For the publication, Kaikei Kozo no Ronri (Logic of Accounting
Structure). Zeimukeiri Kyokai Co., Ltd., (Jun. 1994).

The Japan Boki
Association

03/09/04

Kouhei Ohnishi(Prof., Fac. of Science andTechnology)

EPE-PEMC Council Award

For his outstanding achievements in motion control including
invention of the disturbance observer and the first realizationof haptic sensation for robotic forceps.

EPE

09/09/04

Masafumi Hagiwara(Prof., Fac. of Science andTechnology) et al.

Japan Society of Kansei
Engineering (JSKE)(Best Paper Award)

For the paper “Creativity Support System for Visual
Imagination Based on Analogy and Arrangement of Concepts,”
Kansei Kogaku Kenkyu, Vol.3-1, No. 5, (Mar. 2004).

JSKE

09/09/04

Naoki Aikawa(Prof., Sch. of Medicine,Dir. of Keio University
Hospital)

FY2004 Distinguished
Emergency Services
Contributor Commendation

For best effort in guidance and education as a paramedic
instructing physician and contributions as a committee
member to improving the emergency medical system, as wellas to raising the level of emergency services.

Fire and Disaster
Management
Agency, Ministry ofInternal Affairs andCommunications

Yoshio Ohno
(Prof., Fac. of Science andTechnology)

Japan Society for Software
Science and Technology(JSSST) DistinguishedAchievements Award

For best effort as an editorial committee member in the
production and publication of the JSSST’s journal Computer
Software for over 20 years since establishment of the JSSST.

JSSST

09/06/04

20/06/04

16/09/04

46
Awards for Research Activities, FY2004

Keio University Annual Report on Research Activities 2004–2005

19/05/04

KEIO U-honbun̲E 05.11.29 7:36 PM ページ 47

Date Awarded(DD/MM/YY)

WinnerAward

Reason for Award

Awarding Institution

Date Awarded Winner(DD/MM/YY)

Award

Reason for Award

Awarding Institution

24/11/04

Toshio Suda
(Prof., Dept. of Cell
Differentiation, Sakaguchi
Laboratory of Developmental
Biology, Sch. of Medicine),
Atsushi Hirao(Assc. Prof., Dept. of Cell
Differentiation, Sakaguchi
Laboratory of Developmental
Biology, Sch. of Medicine),
Fumio Arai
(Instr., Dept. of Cell
Differentiation, Sakaguchi
Laboratory of Developmental
Biology, Sch. of Medicine)

41st Erwin von Balz Prize(Second Prize)

For research results representing the first dynamic
demonstration of molecular mechanism control from the niche
of imago bone marrow hematogenic stem cells.

Boehringer
Ingelheim GmbH

12/11/04

Akira Haseyama(Prof., Fac. of Letters)

Keio Award

For the publication, Nihon Kodai no Ho to Saiban (Law and
Trials in Ancient Japan), Sobunsha Publishing Co., (Mar. 2004).

Keio University

12/11/04

Sahoko Kaji(Prof., Fac. of Economics)

Keio Award

For the publication, Kokusai Tsuka Taisei no Keizaigaku (The
Economics of the International Currency System), Nihon
Keizai Shimbun, Inc. (Feb. 17, 2004).

Keio University

12/11/04

Ryosei Kokubun(Prof., Fac. of Law)

Keio Award

For research regarding the politics and bureaucracy ofcontemporary China.

Keio University

12/11/04

Atsushi Yashiro(Prof., Fac. of Business andCommerce)

Keio Award

For the publication, Human Resource Management ofManagerial and Professional Workers, Yuhikaku PublishingCo., Ltd. (Sep. 2002).

Keio University

12/11/04

Takeji Nishikawa(Prof., Sch. of Medicine)

Keio Award

For contributions in internationalization of dermatology.

Keio University

Yasuhiro Koike(Prof., Fac. of Science andTechnology)

Takayanagi Memorial
Award

For achievement in the development and practical use of ultrahigh speed plastic optical fiber.

Takayanagi
Foundation forElectronics Scienceand Technology

12/11/04

Toshiaki Makabe(Prof., Fac. of Science andTechnology)

Keio Award

For achievements in research related to hyperfine plasma
processing theory for semiconductor and design technology.

Keio University

03/03/05

Fumiko Yonezawa(Prof. Emer.)

L’Oréal UNESCO for Womenin Science Award

For achievements in elucidating amorphous semiconductors
and liquid metals through advanced theory and computer
simulations.

UNESCO

12/11/04

Masahiro Fukaya(Prof., Fac. of Policy
Management)

Keio Award

For groundbreaking research dealing with sociosemantics andtextual semantic space analysis systems.

Keio University

22/03/05

Yasushi Watanabe(Assc. Prof., Fac. ofEnvironmental Information)

1st Japan Society for
Promotion of Science (JSPS)Award

For ethnographic research on the political science of culture
and community in present-day America.

JSPS

12/11/04

Yasushi Watanabe(Assc. Prof., Fac. ofEnvironmental Information)

Keio Award

For publication of Afuta Amerika—Bosutonian no Kiseki to“Bunka no Seijigaku” (After America—Trajectory of the
Bostonians and “The Political Science of Culture” ), Keio
University Press (May 2004).

Keio University

22/03/05

Yasushi Watanabe(Assc. Prof., Fac. ofEnvironmental Information)

1st Japan Academy Learning
Encouragement Award

For ethnographic research on the political science of culture
and community in present-day America.

Japan Academy

27/03/05

Yasuaki Einaga(Assc. Prof., Fac. of Scienceand Technology)

The Chemical Society ofJapan (CSJ) Award forYoung Chemists

For achievement relating to “design and characterization ofnovel photo-controllable magnetic materials.”

CSJ

47

Awards Conferred by Keio University
Date Awarded(DD/MM/YY)

WinnerAward

Reason for Award

Awarding Institution

15/02/04

Masataka Kuwana(Asst. Prof., Sch. ofMedicine)

5th Keio University
Intellectual Property CenterAward

For invention of diagnostic for scleroderma.

Keio University
Intellectual Property
Center

12/06/04

Masahiro Toda
(Instr., Sch. of Medicine)

Sanshikai Award

For the results of research in immunotherapy for central
nervous system diseases.

Sanshikai, School of
Medicine, Keio
University

12/11/04

Kazunori Shibuya(Instr., Sch. of Medicine)

Sanshikai Encouragement
Award

For discovery of keratin-annexed protein (KAP) gene clusters
existing in gene introns on chromosome No. 21.

Sanshikai, School of
Medicine, Keio
University

12/11/04

Yasushi Nakao(Asst. Prof., Sch. ofMedicine)

Sanshikai Encouragement
Award

For pioneering work in the new medical field of “treatment for
the hands of musical performers.” This work includes
activities for enlightening specialists as well as educational
activities for preventing disorders directed toward
professional performers and children who play instruments.

Sanshikai, School of
Medicine, Keio
University

12/11/04

Takao Saruta(VP/Prof., Sch. of Medicine)

Fukuzawa Award

For achievement in research concerning the role of kidneys
and endocrine factors in the onset and development ofhypertension.

Keio University

12/11/04

Ikuyo Kaneko(Prof., Grad. Sch. of Mediaand Governance/Fac. of
Policy Management)

Fukuzawa Award

For research into network communities and related practiceactivities.

Keio University

48

Index
21st Century COE Program
3–5, 16, 17, 23–32, 35, 36Center for Integrated Medical ResearchInstitute of Integrated Medical Research
3, 11, 12, 20, 26, 31, 34
Center for Research Promotion (CRP)
3, 4, 21, 22, 50
Commissioned research
3, 9, 10, 22, 36, 42, 43Competitive research fund
38–40
Consortium
13, 14, 19
Contracts
3, 36, 41
Doctorate
Course doctorate
41
Doctoral Program
9, 13, 41
Doctorates
28, 41Dissertation doctorate
41
General administrative expenses
37, 38Grants3, 9, 11, 28, 33, 36, 39
Incubation
3, 13, 14, 18, 34
Indirect expenses
36–38
Industry-Academia-Government, Industry-Academia,
Industry-Government-Academia
3–4, 9, 15, 18, 22, 31, 34, 36, 44, 45
Institute for Advanced Biosciences (IAB) 3, 4, 17, 18, 21, 29, 40, 44, 45, 50
Intellectual Property Center (IPC)3, 4, 9, 12, 20, 31, 43–45, 48, 50
Joint research
3, 8, 9, 12–15, 17, 18, 22, 25, 27, 31, 32, 34, 36, 40, 43
Keio Leading-edge Laboratory of Science and Technology (KLL)3, 4, 9, 10, 21, 22, 34, 42
Keio Research Institute at SFC
3, 4, 13, 14, 21, 42
Keio Researchers Information System (K-RIS)/
research information
4

Keio Techno-Mall
4, 9, 10, 21, 29
Liaison Office4, 10
Licensing
3, 4, 43, 44
Organization for Research Advancement and Administration (ORAA)
1, 3, 4, 21, 50
Patent applications
3, 43
Post–doctoral Fellow (PD)27, 31, 32
Program to Encourage the Development of Strategic Research Centers
7, 19, 35, 40
Research Assistant (RA)20, 29–32
Research Park11, 12, 25, 26, 31, 34
Researcher
3–6, 9, 12–16, 18–28, 30–33, 35, 38–42
Researcher, tenured
41
Researcher, non-tenured
41
SFC Open Research Forum4, 13, 21
Specified contributions
10, 36
Subsidies3, 33, 36, 39
MEXT Grants-in-Aid for Scientific Research (Kakenhi )11, 33, 36, 39
MEXT Special Coordination Funds for Promotion of Science and Technology
19, 35, 39, 40
Technical guidance
36, 46
Technology transfer
4, 12, 30, 43, 44
Venture3, 4, 13, 14, 18, 21, 31

Awards for Research Activities, FY2004

Keio University Annual Report on Research Activities 2004–2005

20/01/05

KEIO U-honbun̲E 05.11.29 7:37 PM ページ 49

Contact Information
Mita Campus

Shinanomachi Campus

2-15-45 Mita, Minato-ku, Tokyo 108-8345
Tel +81-3-3453-4511

35 Shinanomachi, Shinjuku-ku, Tokyo 160-8582
Tel +81-3-3353-1211● 8-minute walk from Tamachi St.
(JR Yamanote Line or JR Keihin Tohoku Line);
Approximately 10 minutes by train from Tokyo
to Tamachi.
Approximately 20 minutes by train from Ueno
to Tamachi.
Approximately 15 minutes by train from Shibuya
to Tamachi.
● 7-minute walk from Mita St. (Asakusa or Mita Line);
Approximately 15 minutes by train from Suidobashi to Mita.
● 8-minute walk from Akabanebashi St. (Oedo Line)● 1-minute walk from Shinanomachi St. (JR Sobu Line);
Approximately 6 minutes by train from Shinjuku to
Shinanomachi.
Approximately 25 minutes by train from Tokyo to
Shinanomachi.
● 5-minute walk from Kokuritsu-kyogijo St. (Oedo Line)

Tsuruoka Town Campus■ Center Building

Shonai Airport

Bio-Lab, Institute forAdvanced Biosciences (IAB),
Keio University

ata

Sak
R7

a
gat
Nii

Tsuruoka
ChuoHigh School

JR Tsuruoka St.

Yamagata University Faculty of Agriculture
Hie
ShrineTsuruoka Minami Tsuruoka Kita
High School
High School
Tsuruoka TechnicalHigh School
Chido
MuseumOhyamaCity Library
Police Box■ Bio-lab403-1 Nipponkoku, Daihouji, Tsuruoka-shi,
Yamagata 997-0017
TEL +81-235-29-0534

49

Mita Campus● CRP: Center for Research Promotion
crp@keio.ac.jp● IPC: Intellectual Property Center
toiawasesaki-ipc@adst.keio.ac.jp● Head Office of Research Administration
ora-honbu@adst.keio.ac.jp● Office of Research Administration, Mita Campus
mshien-ft@adst.keio.ac.jp● ORAA: Office for Research Advancement andAdministrationoraa-jimukyoku@adst.keio.ac.jp

N14-1 Baba-cho, Tsuruoka-shi, Yamagata 997-0035
TEL +81-235-29-0800

Tsuruoka Park

Daitokuji
TempleHiyoshi Campus● Office of Research Administration, Hiyoshi Campus
ras-hiyoshi@adst.keio.ac.jp

Tsuruoka
City Hall
Chidokan

a/A

kita

Yagami Campus● Office of Research Administration,
Yagami Campus
yg-shien@adst.keio.ac.jpkatTsuruoka Town Campus
Campus Center, Institute forAdvanced Biosciences (IAB),
Keio University

Yamagata

Tsuruoka Park Rest House
Training Building

Hiyoshi Campus

Shonan Fujisawa Campus

4-1-1 Hiyoshi, Kohoku-ku, Yokohama-shi,
Kanagawa 223-8521
Tel +81-45-563-1111

5322 Endo, Fujisawa-shi, Kanagawa 252-8520
Tel +81-466-47-5111

HaguroR112

Shinanomachi Campus● Office of Research Administration,
Shinanomachi Campus
ras-shinanomachi@adst.keio.ac.jp● By air: approximately 60 minutes from Tokyo Haneda
Airport to Shonai Airport, approximately 25 and 18
minutes by car from Shonai Airport to Center Building
and Bio-lab, respectively.
● By train: approximately 120 minutes by Joetsu
Shinkansen (bullet train) from Tokyo St. to Niigata St.,
then approximately 120 minutes by Uetsu Honsen(main line) from Niigata St. to Tsuruoka St., then 5
minutes by car.

● 1-minute walk from Hiyoshi St. (Tokyu Toyoko Line);
Approximately 25 minutes by train from Shibuya to
Hiyoshi (20 minutes by express).
Approximately 20 minutes by train from Yokohama to
Hiyoshi (15 minutes by express).
Approximately 20 minutes by train from Shin-Yokohama
to Hiyoshi via Kikuna.

● Approximately 15 minutes by bus from Shonandai St.
(Odakyu Enoshima Line, Sagami Tetsudo Izumino Line,or Yokohama Subway Line);
Approximately 30 minutes by train from Yokohama to
Shonandai.
● Approximately 25 minutes by bus from Tsujido St.
(JR Tokaido Line);
Approximately 30 minutes by train from Yokohama to
Tsujido.

Yagami Campus

Shin-Kawasaki Town Campus

JR local lines

3-14-1 Hiyoshi, Kohoku-ku, Yokohama-shi,
Kanagawa 223-8522
Tel +81-45-563-1141

144-8 Ogura, Saiwai-ku, Kawasaki-shi,
Kanagawa 212-0054
TEL +81-44-580-1580

JR Shinkansen● 15-minute walk from Hiyoshi St. (Tokyu Toyoko Line);
Approximately 25 minutes by train from Shibuya to
Hiyoshi (20 minutes by express).
Approximately 20 minutes by train from Yokohama to
Hiyoshi (15 minutes by express).
Approximately 20 minutes by train from Shin-Yokohama
to Hiyoshi via Kikuna.
● Approximately 10 minutes by car from Shin-Kawasaki St.
(JR Yokosuka Line);
Approximately 12 minutes by train from Shinagawa to
Shin-Kawasaki.
Approximately 9 minutes by train from Yokohama to
Shin-Kawasaki.

● 10-minute walk from Shin-Kawasaki St.
(JR Yokosuka Line);
Approximately 20 minutes by train from Tokyo toShin-Kawasaki.
Approximately 12 minutes by train from Shinagawa to
Shin-Kawasaki.
Approximately 9 minutes by train from Yokohama to
Shin-Kawasaki.
● 15-minute walk from Kashimada St. (JR Nanbu Line);
Approximately 7 minutes by train from Kawasaki to
Kashimada.

Shonan Fujisawa Campus● Office of Research Administration,
Shonan Fujisawa Campus
kri-sfc@sfc.keio.ac.jp● Shin-Kawasaki Town Campus
k2-tc@adst.keio.ac.jp● Tsuruoka Town Campus
office@ttck.keio.ac.jp

Private railways

JR Yamanote Line

SubwayJR KeihinTohoku LineBus

Oedo Line
Nanboku Line
Shinjuku

Nagatsuta

Sagamiono

JR Nanbu Line

HiyoshiCampus

MachidaShinanomachi
Campus

JR Chuo Line

YagamiCampus

Odakyu Line

Chuo-rinkan
JR Yokohama Line

HiyoshiDen-en-chofu
Musashi-Kosugi

YamatoTokyu
Toyoko LineJiyu-gaoka

Mita Line

Ebisu

JR Tokaido Shinkansen

Kikuna Shin-Kawasaki

Tokyu Meguro Line

Town Campus

JR Tokaido Shinkansen

Futamatagawa

Shonan Fujisawa
Campus

Sotetsu Izumino Line

JR Yokosuka Line

Shin-Kawasaki

Tokyo

HibiyaNakameguro

Hibiya Line

Akabanebashi
Asakusa Line

Azabu-juban
Shin-Yokohama

Odakyu Enoshima Line

Mita
CampusMeguroGotandaDaimonMita
Hamamatsucho

Yokohama

Kawasaki

JR Tokaido Line

Oimachi

Shinagawa

Keikyu-Kamata
Totsuka
TsujidoKeihinkyuko LineFujisawa
Haneda Airport

Tokyo Monorail

TamachiShinbashi

Oedo Line

Kashimada
Shonandai

Akihabara

Ochanomizu

Suidobashi

Nanboku Line

ShibuyaAzaminoSotetsu Line

JR Sobu Line
Iidabashi

Kokuritsukyogijyo

Futakotamagawa

Tokyu Denentoshi Line

Yokohama
SubwayLine

Yotsuya

YoyogiShinanomachi

50
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