Fine Chemicals
Custom Manufacturing
We produce industrial and pharmaceutical chemicals from R&D scale to a large amount, onassignments. Especially as for pharmaceutical intermediates, we undertake to manufacture themunder a strict quality control system, applying our expert technology, by utilizing facilities suited
GMP requirement. Please contact us for your request.

AzidesAmination

Heterocycles

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Fine Chemicals
Reduction

Oxidations

Acid chlorides and their derivatives

Sulfonations(Formylations)Vilsmeier reaction

Duff reaction

Cyanations

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Fine Chemicals
Halogenations

Hofmann reaction

Friedel-Crafts reaction

Fries rearrangement

Curtius rearrangement

Mannich reaction

Chloromethylation

Hazardous BCM contamination is suppressed by our technology.
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Fine Chemicals
Facility Outline

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Production Plant(Takasago & Takefu)
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5 - 140-5 - 180

211
6582
112Plant

Pilot Plant

Pressure Limit (MPa abs)
Decompossion Limit(KPa abs)
Temperature Range for Usage (ºC)

REACTORS

GL 0.5m3
GL 1m3
GL 2m3GL 3m3
GL 5m3
GL 6m3
GL 8m3
GL 12m32

Ni based alloy 3m3

1

SUS 0.5m3
SUS 2m3
SUS 5m31321

SUS 8m3
Distillation Tower (Stage)

Separators(materials)

SUS(30),(35)Basket Centrifuges
Basket Centrifuges(PTFE lining,Ni based (SUS,PTFE lining,Nialloy)
based alloy)
Decanter(SUS)

Dryers (materials)

Double Cone (GL)

Environmental Protection
Equipments

Active Carbon
Absorber

Quality Control

cGMP
ISO9001
ISO14001

Note

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Rotary Drum Filters(SUS)
Double Cone (GL)Nauta Mixers (SUS)
Chamber Type (SUS)
Vacuum Vibrating Type(SUS)
Gravity Sedimentation
Tanks
Active Carbon Absorbers
Waste Liquid Incinerator
cGMP
ISO9001
ISO14001
Passed FDA Inspection(June,1999)

Fine Chemicals
Plant
Pilot plant for pharmaceutical intermediate
Our fine chemicals have characteristic technologies, and we continue supplying functional
materials and intermediates to many fields such as pharmaceutical and electronic industries.
In order to cope to diversifying needs, we built a new pilot plant furnished small and middle size
reactors which was designed for speedy production under appropriate management.
We built additional commercial plant for pharmaceutical intermediates in Takasago plant in 2007.
These investments will enforce our productive capacity and make possible for smoother transition
from laboratory, development stage to commercial production.

Feature of the facility
Under GMP control, this plant is established closed system adequate to prevent contaminationand environmental friendly.
Equipped small and medium-size reactors enable to response various customers needs fromsmall scale at early stage to medium volume of trial timely and at low-cost.
The state-of-the-art data management and monitoring system enable to analyze and review theproduction conditions to optimize them.

Outline of the pilot plant• Five stories building, total floor area is about 1,000m2• Reactors : GL 2000L × 2, GL500L × 2• Stirring wings : Applicable for small quantity• Centrifugals : Ni based alloy and PTFE lining• Dryers : 500L Double cone dryer• The vacuum generator of the acid-proof specification• Environmental protection equipments : Acid ? alkali absorber, active carbon absorber.
• DCS (distributed control system) equipment

Outline of the commercial plant• Five stories building, total floor area is about
1,150m2• Reactors : GL 6000L × 2, GL8000L × 2• Stirring wings : The twin star, Full zone
• Centrifugals : Ni based alloy (Horizontal)• Dryers : 3000L Double cone dryer• The vacuum generator of the acid-proof
specification• Environmental protection equipments : Acid ? alkali
absorber, active carbon absorber.
• DCS (distributed control system) equipment

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