Peptide Antisera and Monoclonal Antibodies (2)Manufacturer:

Distributor:

YANAIHARA INSTITUTE INC.

PEPTIDE INSTITUTE, INC.

2480-1 AWAKURA, FUJINOMIYA-SHISHIZUOKA, 418-0011
JAPAN4-1-2 INA, MINOH-SHIOSAKA, 562-8686
JAPAN

PHONE: +81-(0)544-22-2771
FAX:+81-(0)544-22-2770
E-mail: ask＠yanaihara.co.jp
http://www.yanaihara.co.jp

PHONE: +81-(0)72-729-4121
FAX:+81-(0)72-729-4124
E-mail: info＠peptide.co.jp– 273 –

Peptide Antisera andAntisera of Yanaihara Institute Inc. ………………… 274

Monoclonal Antibodies

Antisera ofYanaiharaInstitute Inc.

Antisera of YANAIHARA INSTITUTE INC.
CodeProduct

Host (Animal)

Price:YenY260

Anti Acidic-FGF (1-15) (Bovine) Serum

Rabbit35,000

Y352

Anti ACTH (1-23) (Rat) Serum

Rabbit35,000

Y351

Anti ACTH (21-39) (Rat) Serum

Rabbit35,000

Y350

Anti ACTH (Rat) Serum

Rabbit35,000

Y410

Anti Angiostatin (128-141) (Mouse) Serum

Rabbit35,000

Y411

Anti Angiostatin (285-294) (Mouse) Serum

Rabbit35,000

Y330

Anti Atrial Natriuretic Peptide (ANP) (Rat) Serum

Rabbit35,000

Y251

Anti Basic-FGF (1-9) (Human) Serum

Rabbit35,000

Y250

Anti Basic-FGF (Human) Serum

Rabbit35,000Y170

Anti Bombesin Serum

Guinea Pig

35,000

Y340

Anti Calcitonin Gene-Related Peptide (α-CGRP) (Rat) Serum

Rabbit35,000Y470

Anti Carassius RFamide Serum

Rabbit35,000

Y294

Anti Chromogranin A (1–28) (Rat) Serum

Rabbit35,000

Y292

Anti Chromogranin A (343-360) (Rat) Serum

Rabbit35,000

Y293

Anti Chromogranin A (344-374) (Human) Serum

Rabbit35,000

Y290

Anti Chromogranin A (359-389) (Rat) Serum

Rabbit35,000

Y291

Anti Chromogranin A (94-130) (Rat) Serum

Rabbit35,000

Y221

Anti C-Peptide I (Rat) Serum

Rabbit35,000

Y222

Anti C-Peptide I (Mouse) Serum

Rabbit35,000

Y220

Anti C-Peptide II (Rat) Serum

Rabbit35,000

Y223

Anti C-Peptide II (Mouse) Serum

Rabbit35,000Y210

Anti CRF (24-41) (Human, Rat) Serum

Rabbit35,000

Y211

Anti CRF (3-41) (Human, Rat) Serum

Rabbit35,000Y230

Anti EGF (Human) Serum

Rabbit35,000Y231

Anti EGF (Rat) Serum

Rabbit35,000Y300

Anti α-Endorphin Serum

Rabbit35,000

Y182

Anti Galanin (1-15) Serum

Rabbit35,000

Y183Anti Galanin (15-29) (Rat) Serum

Rabbit35,000

Y186

Anti Galanin (20-29) (Rat) Serum

Rabbit35,000

Y184

Anti Galanin (9-30) (Human) Serum

Rabbit35,000

Y180

Anti Galanin (Porcine) Serum

Rabbit35,000Y110

Anti Gastrin 34 (1-15) (Human) Serum

Rabbit35,000Y100

Anti GIP(1-30)-OH (Porcine) Serum

Rabbit35,000

Y101

Anti GIP (Human) Serum

Rabbit35,000

Y102

Anti GIP (Rat) Serum

Rabbit35,000Y103

Anti GIP (18–42) (Rat) Serum

Rabbit35,000

Y324

Anti Glicentin (1-32) (Rat) Serum

Rabbit35,000Y320

Anti GLP-1 (7-36)-NH2 (Human) Serum

Rabbit35,000

Y321

Anti GLP-2 (14-33) (Rat) Serum

Rabbit35,000– 274 –Antisera of Yanaihara Institute Inc. (continued)
CodeProduct

Host (Animal)

Price:Yen

Y322

Anti GLP-2 (Rat) Serum

Rabbit35,000

Y323

Anti GLP-2 (Mouse) Serum

Rabbit35,000

Y311

Anti Gonadotropin-Releasing Hormone-AssociatedRabbit35,000

Rabbit35,000Pepteide (GAP) (34-56) (Human) Serum

Y312

Anti Gonadotropin-Releasing Hormone-AssociatedPeptide (GAP) (28-56) (Rat) Serum

Rabbit35,000

Y160

Anti GRP (Porcine) SerumRabbit

35,000

Y440

Anti Humanin Serum

Rabbit35,000

Y370

Anti Insulin (Human) Serum

Guinea Pig

35,000

Y380

Anti Luminal Cholecystokinin-Releasing Factor (LCRF) (Rat) Serum

Rabbit35,000Y140

Anti Met-Enkephalin-Arg6-Gly7-Leu8 Serum

Rabbit35,000Y120

Anti Motilin (Dog) Serum

Rabbit35,000

Y121

Anti Motilin (Human, Porcine) Serum

Rabbit35,000+Y400

Anti Na Channel II (467-485) (Rat) Serum

Rabbit35,000Y130

Anti Neurotensin Serum

Rabbit35,000Y430

Anti Nociceptin/Orphanin FQ (Human, Rat) Serum

Rabbit35,000

Y061Anti NPY(1-19) (Human, Rat, Mouse) Serum

Rabbit35,000Y060

Anti NPY (Human, Rat, Mouse) Serum

Rabbit35,000Y460

Anti Obestatin (Rat, Mouse) Serum

Rabbit35,000

Y461

Anti Obestatin (Human) Serum

Rabbit35,000Y450

Anti Orexin A Serum

Rabbit35,000

Y451

Anti Orexin B (Mouse, Rat) Serum

Rabbit35,000

Y042

Anti PACAP (1-15) (Human) Serum

Rabbit35,000

Y051

Anti PACAP27 (13-27) (Human) Serum

Rabbit35,000Y050

Anti PACAP27 (Human) Serum

Rabbit35,000

Y041

Anti PACAP38 (22-38) (Human) SerumRabbit

35,000Y040

Anti PACAP38 (Human) Serum

Rabbit35,000Y090

Anti Pancreastatin (33-51) (Rat) Serum

Rabbit35,000Y080

Anti Pancreatic polypeptide (PP) (18-36) (Human) Serum

Rabbit35,000

Y072

Anti Peptide YY (PYY) (Human) Serum

Rabbit35,000Y070

Anti Peptide YY (PYY) (Porcine, Rat) Serum

Rabbit35,000

Y021

Anti PHI (13-27) (Human) Serum

Rabbit35,000Y020

Anti PHI (Human) Serum

Rabbit35,000

Y022

Anti PHI (Rat) Serum

Rabbit35,000Y185

Anti Preprogalanin (89-124) (Rat) Serum

Rabbit35,000

Y190

Anti Preprorenin (21-64) (Human) Serum

Rabbit35,000

Y191

Anti Prorenin (265-294) (Human) Serum

Rabbit35,000

Y192

Anti Prorenin (314–337) (Human) Serum

Rabbit35,000

Y310

Anti Pro-LH-RH (1-26) (Human) Serum

Rabbit35,000

Y480

Anti PSA (53–92) (Human) Serum

Rabbit35,000

Y421

Anti PTH (1-15) (Rat) Serum

Rabbit35,000– 275 –

Peptide Antisera andAnti GRF/GH-RH (Rat) Serum

Monoclonal Antibodies

Y390

Antisera of Yanaihara Institute Inc. (continued)
CodeProduct

Host (Animal)

Price:YenY420

Anti PTH (1-34)-NH2 (Rat) Serum

Rabbit35,000

Y201

Anti PTHrP (1-34)-NH2 Serum

Rabbit35,000

Y202

Anti PTHrP (15-34)-NH2 Serum

Rabbit35,000

Y441

Anti Rattin-24 Serum

Rabbit35,000Y280

Anti Retinoblastoma (RB) Protein (901-928) (Human) Serum

Rabbit35,000Y030

Anti Secretin (Human) Serum

Rabbit35,000

Y031

Anti Secretin (Porcine) Serum

Rabbit35,000

Y032

Anti Secretin (Rat) Serum

Rabbit35,000Y150

Anti Substance P Serum

Rabbit35,000Y240

Anti TGF-α (Human) Serum

Rabbit35,000

Y241

Anti TGF-β1 (Human) Serum

Rabbit35,000

Y360

Anti Urocortin (3-40) (Rat) Serum

Rabbit35,000

Y361

Anti Urocortin (Rat) Serum

Rabbit35,000

Y362

Anti Urocortin 1 (Mouse, Rat) Serum

Rabbit35,000

Y363

Anti Urocortin 2 (Mouse) Serum

Rabbit35,000

Y364

Anti Urocortin 3 (Mouse) Serum

Rabbit35,000

Y365

Anti Urocortin 2 (Rat) Serum

Rabbit35,000Y010

Anti VIP (Human, Porcine) Serum

Rabbit35,000

YA010

Anti Amyloid β Protein (1-40) (Human) Serum

Rabbit40,000

YP060

Anti ATP Receptor P2X4 (370-388) (Rat) Serum

Rabbit40,000

YP030

Anti CCK-8 Serum

Rabbit40,000

YP070

Anti G-Protein: Gα olf (23-38) (Human) Serum

Rabbit40,000

YP071

Anti G-Protein: Gα i3 (105-127) (Human) Serum

Rabbit40,000

YP010

Anti LH-RH Serum

Rabbit40,000

YP050

Anti NO Synthase I (998-1024) (Human) Serum

Rabbit40,000

YP051

Anti NO Synthase II (77-105) (Rat) Serum

Rabbit40,000

YP080

Anti S100β(41-60) (Human, Mouse, Rat) Serum

Rabbit40,000

YP081

Anti S100β(74-92) (Human, Mouse) Serum

Rabbit40,000

YP020

Anti Somatostatin Serum

Rabbit40,000

YP040Anti Total Glucagon Serum

Rabbit40,000

YC010

Anti IL-1α(Rat) Serum

Rabbit60,000

YC011

Anti IL-1α (Rat) Serum

Goat

60,000

YC020

Anti IL-1β (Rat) Serum

Rabbit60,000

YC021

Anti IL-1β (Rat) Serum

Goat

60,000

YC022

Anti IL-1β (Rat) Monoclonal Antibody

YC040

Anti Leptin (Rat) Serum

YC030

Anti TNF-α (Rat) Serum

Rabbit60,000

YC031

Anti TNF-α (Rat) Serum

Goat

60,000

YC032

Anti TNF-α (Rat) Monoclonal Antibody

60,000
Rabbit– 276 –

60,00060,000EIA or ELISA Kits of Yanaihara Institute Inc.
YK-Series : Domestic Service Only ( 国内限定販売 )

YK010
YK011
YK012
YK013
YK050
YK051
YK052
YK060
YK070
YK080
YK081
YK090
YK100
YK111
YK131
YK140
YK141
YK142
YK150
YK160
YK190
YK191
YK200
YK210
YK230
YK231

C-Peptide (Rat)-EIA Kit
C-Peptide I (Mouse)-EIA Kit
C-Peptide II (Mouse)-EIA Kit
C-Peptide (Mouse)-EIA Kit
Leptin (Rat)-ELISA Kit
Leptin-HS (Rat)-ELISA Kit
Leptin (Mouse)-ELISA Kit
Insulin-ELISA Kit
Chromogranin A (Human)-EIA Kit
Peptide YY (Human)-EIA Kit
Peptide YY (Rat)-EIA Kit
Glucagon (Human, Rat, Mouse)-EIA Kit
NO Synthase I (Human, Rat)-EIA Kit
Glicentin (Rat)-EIA Kit
CRF (Human, Rat, Mouse)-HS ELISA Kit
GLP-2 (Rat)-EIA Kit
GLP-2 (Human)-EIA Kit
GLP-2 (Mouse)-EIA Kit
S-100β (Human)-ELISA Kit
GLP-1 (Human, Rat, Mouse)-EIA Kit
Urocortin 2 (Mouse)-EIA Kit
Urocortin 2 (Rat)-EIA Kit
Urocortin 3 (Mouse, Rat)-EIA Kit
Urocortin 1 (Mouse, Rat)-EIA Kit
Obestatin (Rat, Mouse)-EIA Kit
Obestatin (Human)-EIA Kit

Assay Range

Price:Yen

1.56 - 50 ng/ml
0.617 - 50 ng/ml
0.412 - 100 ng/ml
0.412 - 100 ng/ml
80 - 20,000 pg/ml
78.1 - 2500 pg/ml
0.313 - 20 ng/ml
0.137 - 100 ng/ml
0.1 - 10 pmol/ml
10 - 10,000 pg/ml
50 - 10,000 pg/ml
50 - 10,000 pg/ml
0.98 - 1000 ng/ml
206 - 50,000 fmol/ml
0.078 - 2.5 ng/ml
0.137 - 100 ng/ml
0.137 - 100 ng/ml
0.412 - 100 ng/ml
98 - 63,000 pg/ml
206 - 50,000 pg/ml
0.82 - 200 ng/ml
1.56 - 100 ng/ml
0.41 - 100 ng/ml
1.563 - 100 ng/ml
0.082 - 20 ng/ml
0.412 - 100 ng/ml

76,00076,00076,00076,00060,00060,00060,00050,00076,00076,00076,00076,00076,00076,00079,00076,00076,00076,00076,00076,00076,00076,00076,00076,00076,00076,000

Rat C-peptide EIA Kit (YK010)
C- ペプチドは、インスリンの前駆体であるプロインスリンのプロセシングにより、インスリンとほぼ等モル比で血中に放出されます。従って、 C- ペプチドの血中濃度は膵 B 細胞からのインスリン分泌をよく反映しているとされています。また、インスリン投与中においても、血中インスリン濃度に影響されることなく B 細胞からの C- ペプチドの分泌を測定できますので、膵 B 細胞機能検査としては血中 C- ペプチドの測定がインスリン測定よりむしろ優れているという利点があります。人では、既に糖尿病を対象とする臨床検査試薬として C- ペプ
チドの RIA 系は、インスリン測定とともに高い評価を受けています。
31 アミノ酸残基からなるラット C- ペプチドには、 I 型と II 型の 2 種類が存在しますが、それらは 8 位と 17位のアミノ酸残基のみが置換されており、両者の 18 位から C- 末端までのアミノ酸配列は一致しています。
こうした背景に基づき、矢内原研究所では、ラット C- ペプチド C- 末端部を認識するポリクローナル抗体を用い、安定で高感度のラット C- ペプチド特異的 EIA 系を確立するに至りました。本 EIA 系はラット膵 B 細胞機能検査試薬として初めて市販されるものであります。
本 EIA 系では、標準抗原としてラット C- ペプチド -I 、標識抗原としてビオチン化ラット C- ペプチド -I を用い、ラッ トの血漿 および尿 中の C - ペプチド の測定に 使用でき ます。添 加回収試 験 ( 1 02 . 2 - 1 0 6 . 9 % ) 、同時再現性及び日差再現性はそれぞれ CV : 3.38-8.83 及び 5.56-8.41 であり、共に満足すべき結果を得ています。
＜文献＞
1) B. Gonen et al., In "Proinsulin, Insulin, C-Peptide" (Eds. S. Baba, T. Kaneko, and N. Yanaihara)
Excepta Medica, Amsterdam, pp 246 (1979).
2) H. Yasuda et al., Endocrinol. Jpn., 23, 271 (1976).
3) J. Markussen and F. Sundby, Eur. J. Biochem., 25, 153 (1972).
4) H.S. Tager and D.F. Steiner, J. Biol. Chem., 247, 7936 (1972).
5) C. Yanaihara et al., In "Proinsulin, Insulin, C-Peptide" (Eds. S. Baba, T. Kaneko, and N. Yanaihara)
Excepta Medica, Amsterdam, pp 87 (1979).

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Peptide Antisera andProduct

Monoclonal Antibodies

Code– 278 –