Hiroshima International University
Faculty of Pharmaceutical Sciences

Kure Campus
5-1-1 Hirokoshinkai, Kure city, Hiroshima, 737-0112, Japan
http://www.hirokoku-u.ac.jp/pharm/Contents
1.

Message from the President

2.

Message from the Dean

3.

History4.

Organization

5.

Faculty of Pharmaceutical Sciences

6.

Campus Map in Kure Campus

7.

Faculty Members (Professor) and Research Work

8.

International Exchange

9.

Club Activities

10.

Location

11.

SightseeingMessage from the President

Hiroshima International University (HIU) wasestablished in 1998, and there are approximately 4,000
students now taking a wide range of courses in the field ofhealth, medical services and welfare. Our graduate school
started in 2003, and now has five master’s courses andfour doctoral courses including pharmaceutical sciences.
In the undergraduate school, we have been promotinginterprofessional education, in which, for example,
students learn the roles and responsibilities of otherproviders and how the team works together to providecare, promote health, and prevent disease.
In today's society, where the average life expectancy is increasing and the birthrate is
declining and aging, such education has led us to think that we should make further
efforts to promote health.
Therefore, we decided to strengthen education and research for health promotion
throughout the university. As part of that, we have set up a center that accepts healthconsultations and holds health classes for local residents and start the Faculty of
Health and Wellness Sciences and the Faculty of Health and Sports Sciences. These
allow us to cultivate more diverse students to extend healthy life expectancy andimprove quality of life.
It is known that various factors extend healthy life expectancy. Among them, as it
is said that "Good relationships keep us happier and healthier", good relationships arevery important. We, therefore, will make the university a place of learning, where
diverse people can meet, and grow as individuals and as part of their teams.
I welcome you to visit our campuses in Hiroshima and interact with our students
and faculty members to know more about HIU and our activities.

Masuhide Yakehiro

Message from the Dean
Institute of Pharmaceutical sciences in Hiroshima
International University is putting an effort letting all
students acquire necessary knowledge, skill andattitudes, as well as foster a sense of ethics throughpractical training as a pharmacist. We also provide
an education by witch students can create a wide
range of perspective and flexibility. In addition, withregard to the measurement for national examination,
all staffs with expertise are working on an original
system to support the study of each student.
This university will accept students who want tocontribute to the health improvement of people
through pharmaceutics, and those who wish to create
the future of Japan as a pharmacist.

Takamitsu Hori

Message from the Department Chair
The environment surrounding medical care haschanged daily in recent years. The advancement of AI(artificial intelligence) technology can be cited as afactor in such changes. In response to these changes, thepharmacist's abilities should be also required to change
flexibly.
Faculty of Pharmaceutical Sciences of our university
aims to train pharmacists who act responsibly andindependently in society with the catchphrase“pharmacists close to people”.
The meaning of “close to people” includes not only “snuggling with people (beside)”
but also “snuggling with your heart”. The future pharmacist must be required to act
as a member of healthcare professional for patients and users by accurately
grasping and analyzing their physical conditions, and also acting with the rightthoughts. All of our educational staffs will conduct pharmaceutical education to
produce graduates with the qualities mentioned above.
Let's aim to be a pharmacist who learns greatly with our educational staff andcontributes to society!

Masafumi Yamaguchi

History
Hiroshima International University is a member of Josho Gakuen Educational
Foundation together with Osaka Institute of Technology and Setsunan University.

1922

Josho Gakuen Educational Foundation was founded. Kansai Engineering
Technical School was established as the first school of the Foundation.

1949

Osaka Institute of Technology was established.

1975

Setsunan University was established.

1998

Hiroshima International University was established.
Faculty of Health and Welfare and Faculty of Health Sciences were launched.

2001

Faculty of Human Environment was launched.

2002

Faculty of Socio-Environmental Science was launched.

2003

Faculty of Nursing was launched.

2004

Faculty of Pharmaceutical Sciences was launched.

2006

Faulty of Human Environment was reorganized as Faculty of Psychological
Science.
The Faculty of Pharmaceutical Sciences shifted to the six-year system.

2011

Faculty of Health services Management was established.

2012

Graduate School of Pharmaceutical Sciences was set up.

2013

Faculty of Rehabilitation was launched.

2014

Faculty of Clinical Nutrition was launched.

2020

Faculty of Health and Wellness Sciences and the Faculty of Health and Sports
Sciences was launched.

Organization
Josho Gakuen Educational Foundation
Our foundation strives to develop specialist with science –based
practical skills who play an important role in society.

Hiroshima International University
Osaka Institute of Technology
Setsunan University
Josho Gakuen Junior and Senor High School
Josho Keiko Gakuen Junior and Senor High School

Hiroshima International University
The university is specialized in health, medical service and welfare

Kure Campus
Faculty of Pharmaceutical Sciences
Faculty of Nursing
Faculty of Clinical Nutrition

Higashi-Hiroshima Campus
Faculty of Health Sciences
Faculty of Rehabilitation
Faculty of Health and Welfare
Faculty of Psychology
Faculty of Health Services Management

Educational Policy
The School of Pharmaceutical Sciences cultivates students who acquire professional
knowledge and skills together with humanity through the study of Pharmaceutical
Sciences. The School also makes efforts to cultivate students who become excellent
pharmacists in the fields of medical care, human health and welfare. The Graduate
School of Pharmaceutical Sciences contributes to cultivate students who take active
parts in the field of Pharmaceutical Sciences and related area at university, industry
and government.

Curriculum policy
The School of Pharmaceutical Sciences aims to develop young pharmacists who
contribute community medicine based on their professional knowledge and humanity.
Such human resource is required in our society at the new era of 21st century. The
School has following objects and provides specialized curriculum.
・Cultivation of pharmacists with humanity and high ethicalstandards
・Cultivation of pharmacists who are able to contributemedical and health cares in cooperation with other special
personnel.
・Cultivation of pharmacists with professional skills andrespectable personality
・Cultivation of pharmacists with ability to resolve problem
based on scientific grounds
Year 1
The curriculum includes Liberal Arts and Basic Natural Sciences in addition to Basic
Pharmaceutical Sciences. These subjects are provided to students for acquiring a highlevel of knowledge and scientific thinking. The early exposure program for visiting
medical facilities is helpful for students to understand role of pharmacist there.
Years 2-3
The curriculum includes Biological Sciences, Organic Chemistry, Physical Chemistry
Analytical Chemistry and Environmental Chemistry, and related subjects for
Pharmaceutical Sciences. Basic Medical Sciences and Plant Sciences are provided.
These subjects are helpful for students to understand biology of the human body andthe effects of medicinal products together with drug disposition and drug toxicity. In
addition, student’s comprehension about food products and environment problems
are deepened. In the year 3, specialized education subjects such as Laboratory
Teaching are enabling students to learn experimental techniques in Pharmaceutical
Sciences.

Years 4-5
The curriculum includes Clinical Pharmacy together with practical exercise,
Pathophysiology and Pharmacology. From Year 4, students belong to one of researchlaboratories and carry out research work for long-term as graduation studies. During
the second semester in Year 4, students take the Common Achievement Tests (OSCEand CBT). The students who pass the examination are able to go a hospital andpharmacy for pharmacological practical training there for 11 weeks each in Year 5.

Year 6Students complete long-term pharmaceutical research and submit graduate thesis.
The curriculum includes several special subjects regarding the field around medicalcare such as Medical Economy, Home Healthcare, and Nutrition Management. In
addition, Students are provided several subjects for the national examination form
faculty members and they study hard the subjects and may acquire a pharmacist’s
license upon passing the examination.
Graduate School Years 1-4
The program is designed to cultivate students who become researchers oradvanced pharmacists to be able to extend the field of Clinical Pharmacy. They are
expected to become future leaders of the field. The students study individual research
project and learn leading-edge knowledge and technique in Pharmaceutical Sciences.
The graduate students in this course are expected to work in academic institutes,
general hospitals as a leader of pharmacists and pharmaceutical industries foradvances in medical treatment including developing of new drugs.

Campus Map in Kure Campus

6

3
2

4

5

1
10

8
9

１：Faculty of Pharmaceutical Sciences
２：Library
３：Education Center
４：The Secretariat Offices and Faculty of Clinical Nutrition
５：Faculty of Nursing
６：Student Dormitory
７：Gymnasium
8 ：Club House
9 ：Rose Garden
10：Herbal Garden

7

Education Center
No1 Building

Classroom

Learning
Commons(Personal)

Classroom

Learning
Commons(Group)Classroom

Classroom

Rose Garden and Club House

Student Lounge
IPE Practice Room

Cafe
RestaurantPharmaceutical Sciences Building
10F

・Laboratory of Synthetic Organic Chemistry
・Laboratory of Organic and Medicinal Chemistry
・Kampo Medicine and Pharmacognosy
・Fourth joint research room ・Graduate Students' Room

9F

・Laboratory of Environmental Chemistry
・Laboratory of Physiological Chemistry
・Laboratory of Biochemistry
・Laboratory of Pharmacology and Pathophysiology
・Laboratory of Pharmacology
・Low-Temperature room ・ Third Joint Research Room・Graduate Students' Room

8F

・Laboratory of Medicinal and Biochemical Analysis
・Laboratory of Biopharmaceutics and Pharmacokinetics
・Laboratory of Pharmaceutics
・Research Center for Pharmaceutical Health Care and Sciences
・Second Joint Research Room

7F

・Laboratory of Xenobiotic Metabolism and Environmental Toxicology
・Laboratory of Molecular Microbiological Science・Laboratory of Physical Chemistry・First Joint Research Room

6F

・Medical Pharmacy Research Center
・SGD Room ・Simulated Hospital Room・Clean Room・Community Room ・Drug Information Room

5F・Third Training Room・Fourth Training Room・Equipment Storage Room

4F

・Second Training Room・First Training Room・Seminar Room ・Equipment Storage Room

3F

・6301Classroom
・6303 Classroom

2F・Information Practice Room・RI laboratory
・Seminar Room

1F・6302 Classroom・6304 Classroom

・Mass Spectrometry laboratory NMR Spectrometry laboratory
・Laboratory Aminal Rooms
・Administation Offices
・Dean‘s Office ・Reception Room
・Room for Lecture to Graduate Students Conference Room

Laboratory Instruments of Pharmaceutical Sciences

LC-MS-MSNMR 600 MHz

X‐ray Diffraction

Confocal Microscopy

Flow Cytometry

GC-MS

LC-MS

Student Dormitories
Kure Campus

Higashi-Hiroshima Campus

Faculty
Number of Faculty members are 47 (Professor:16, Associate Professor:12,
Assistant Professor:8, Instructor:11)

Professors

Research Interests
Synthetic Organic Chemistry
1. Development of novel fluorescent sialidase probes
2. Development of HN glycoprotein inhibitors against Humanparainfluenza virus
3. Development of novel anti-dengue virus agentsKiyoshi Ikeda PhD

Takuya Sueda PhD

Masamitsu
Nakajima MD PhD

Kazumi Sugihara PhD

Organic and Medicinal Chemistry
1. Development of new synthetic reactions using N-alkynyl andN-allenyl imides
2. Development of new synthetic reactions using hypervalentorganobismuth and organoiodine compounds
3. Design and synthesis of new bioactive heterocyclic compounds
Kampo medicine and Pharmacognosy
1. Drug (Kampo)-induced pneumonia and cigarette smokeinduced Acute eosinophilic pneumonia
2. Clinical education, diagnostic method and clinical effect of
Kampo Medicine (Traditional Herbal Medicine)
3. Clinical application of diagnostic equipment for tongue image
4. Search for bioactive substance from natural sources
Environmental Chemistry
1. The mechanism of sex differences in drug metabolizing
enzymes 2)1H-NMR metabolome analysis
3. Environmental pollution and ecotoxicity caused bypharmaceuticals and personal care products (PPCPs).
4. Appropriate disposal of medical waste

Faculty
Professors

Masafumi
Yamaguchi PhD

Research Interests
Physiological Chemistry
1. Understanding the molecular pathophysiology of
Schwachman-Diamond syndrome, inherited bone marrow
failure syndromes
2. Research on neutrophil extracellular traps
3. Development small molecules for cell differentiation with afocus on leukaemia
Biochemistry
1. Functional analysis of RAS guanyl-releasing protein 2(RasGRP2) in vascular endothelial cells
2. Research on the effects of advanced glycation end products(AGEs) in lifestyle-related diseases

Takamitsu Hori PhD

Pharmacology and Pathophysiology
1. Neuropharmacological study on drug-dependence.
2. Therapeutic mechanism of anti-epileptic treatment.
3. Histopathological study on animal models for human diseases.
4. Elucidation of microglial function.
Kumatoshi
Ishihara PhD

Mitsugu Fujita PhD

Yorimitsu
Kodama PhD

Nobuhiro Mori PhD

Pharmacology
1. Search for natural products to prevent endothelial
oxidative stress
2. Research on intracellular signaling linked with osteogenic
effect of Rac GTPase
3. Pharmacological studies of Rac1 GTPase in bone metabolism
Medicinal and Biochemical Analysis
1. Application of novel chiral surfactant for asymmetric synthesis.
2. Resistance mechanism to cisplatin-based chemotherapy
and therapeutic strategies to overcome resistance
3. Molecular mechanisms of Tob/BTG-mediated signaling pathway.

Biopharmaceutics and Pharmacokinetics
1. Pharmacokinetic analysis of drug-drug interactions
2. Pharmacokinetic and molecular analysis of immunosuppressantin vitro and in vivo
3. Clarification of the modulated function of multidrug resistanceassociated proteins in diseaseFaculty
Professors

Research Interests
Pharmaceutics
Pharmaceutics
1. Nanoparticle-based drug delivery systems for tumor therapy
2. Nanoparticulation of low-soluble drugs
3. Liposomal boron delivery system for neutron capture therapy

Satoshi Kasaoka PhD

Masufumi
Takiguchi PhD

Hiroyasu
Yamanaka PhD

Hiromitsu Aoki PhD

Katsushi Miyake PhD

Akihiro Sawa PhD

Xenobiotic Metabolism and Environmental Toxicology
1. Molecular mechanism of inorganic carcinogenesis (mainly
cadmium)-epigenetic models
2. Defining roles and elucidating mechanism of metallothionein
during chemical carcinogenesis
3. Analyzing exposure effects of bisphenol A and its active
metabolite
Molecular Microbiological Science
1. Analysis of molecular mechanism in virulence expression ofpathogenic factor produced by Aeromonas strains
2. Study on biofilm formation ability in Aeromonas strains
3. Molecular epidemiological analysis of pathogenic bacteria
isolated in hospital
Physical Chemistry
1. Development of novel separation and purification method ofmacromolecules using counter-current chromatography
2. Applied research on separation and purification of enantiomers
with counter-current chromatography
3. Control the solubility of compounds using the co-crystallization
technique

Research Center for Pharmaceutical Health Care and Sciences
1. Study for Pharmaceutical Communication
2. Study for Infection Control
3. Study for appropriate use of drugs
4. Study for health behavior of osteoporosis patient by usingtranstheorical model
5. Clinical Study of Infection prevention and control
6. Clinical Study of prevention of side effect by medicine

Faculty
Visiting professor

Research Interests
Organic and Biomolecular Chemistry
1. Comparative biochemistry of cholanoids (bile acid and bilealcohol)
2. Development of bile acid derivatives for TGR5（GPCR）ligand
3. Exploration of novel agonist and antagonist of Farnesoid X
receptor
1. Research on structure, function and biogenesis of peroxisomes
2. Political study about lysosomal and peroxisomal disorders

Tsuneo Imanaka PhD

AtsukoKuramoto PhD

Language & Culture
1. Research on the cognitive aspects of language processing in the EFL(English as a Foreign Language) environment
2. Development of a web-based learning environment to facilitate EFL
learners’ proficiency levels
3. Exploration of the impact of SNS materials on Japanese EFL students

International Exchange
University and Faculty Exchange Relationships

China

Shandong University School of Pharmacy
Capital Medical University School of Rehabilitation Medicine
Rehabilitation Research Center
Wenzheng College of Soochow University
Suzhou University of Science and Technology

Korea

Daejeon University

TaiwanTzu Chi University of Science and Technology
Central Taiwan University of Sciences and Technology

UK

Oxford University

USA

The University of Tennessee The College of Pharmacy
Mercer University College of Pharmacy
The University of North Carolina at Chapel Hill
Bellevue University

Student Exchange ProgramUSA

The University of Tennessee College of Pharmacy
Mercer University College of Pharmacy

Programs for Undergraduate Students

Club Activities

Location
Japan

Hiroshima International University is locatedin Hiroshima Prefecture.

Hiroshima

Hiroshima Prefecture
Tokyo

HigashihiroshimaCampus

Kyoto
Osaka
Hiroshima city

Fukuoka

Kure Campus

From Higashi-Hiroshima Station on the Shinkansen, High-speed Railway, it takes 1
hour to Fukuoka, 1.5 hours to Osaka, and 4 hours to Tokyo.
Our two campuses are located in Kure city and Higashi-hiroshima city in Hiroshima
prefecture. The Faculty of Pharmaceutical Sciences is located at Kure Campus in Kurecity.

Sightseeing in Hiroshima and Kure
Hiroshima is a center city of economic and industry in western Japan, and is famous
for the world heritage Miyajima and Peace Memorial Park. Kure city is a historic city.
In the old days, it prospered as a military port. Currently there are many shipbuilding
and high-tech factories. Hiroshima has many delicious cuisine such as Okonomiyaki,
Momiji manju and Sea food.

Hiroshima City

Peace Memorial Park

Shopping Arcade

Hiroshima Castle

City Train
Miyajima

Okonomiyaki

Momiji manju

Kure City
Photo：Hiroshima Convention & Visitors Bureau

Hiroshima International University
Faculty of Pharmaceutical Sciences
Kure Campus
5-1-1 Hirokoshinkai, Kure city, Hiroshima, 737-0112, Japan
http://www.hirokoku-u.ac.jp/pharm/

2019.10.10

Vol.1