INDENA TAKES TO in-vitality 2023 ITS GREAT PRODUCTSANTHOCRAN® PHYTOSOME™ AND RELISSA™
Milan, November 22nd 2023 – Indena, the leader company in the identification, development andproduction of high quality active principles derived from plants, attends the 2023 in-vitality edition andwelcomes its guests in Milan, Allianz MiCo - Milano Congressi, Hall 4, booth 261.
Indena will present two of its most important products: its cranberry extract ANTHOCRAN®
PHYTOSOME™ and its lemon balm extract from Melissa officinalis, RELISSA™ - MELISSAPHYTOSOME™, both formulated with a proprietary Technology Platform developed by Indena,
Phytosome™, the breakthrough 100% food-grade delivery system that optimizes the performance ofmany natural actives in multiple ways, positively affecting the bioabsorption, effectiveness and target
reach of a wide range of natural compounds.
At in-vitality 2023 Indena will also share with its stakeholders its vision on sustainability, deepening its
approach to the supply chain management.
LATEST NEWS ON INDENA’S ANTHOCRAN® PHYTOSOME™ AND RELISSATM – MELISSA PHYTOSOME™
ANTHOCRAN® PHYTOSOME™ is Indena’s cranberry extract, a health food ingredient based on
Phytosome™ formulation proprietary technology. ANTHOCRAN® PHYTOSOME™ boasts a unique
phytochemical characterization, which makes it the highest quality cranberry extract on the market. It is
standardized in proanthocyanidins and contains the full polyphenol profile of natural cranberry, including
flavonols, anthocyanins and phenolic acids. ANTHOCRAN® PHYTOSOME™ offers all of cranberries’
virtues to 150 million people prone to Urinary Tract Infections (UTIs).
“A pharmacokinetic study conducted with an innovative method allowed researchers to explore themetabolic profile of cranberry extract, and provide new data to understand its protective activity for theurinary tract – explains Serena Tongiani, Chief Portfolio Officer at Indena -. In particular, valeric acids
and valerolactones, well-known metabolites of proanthocyanidins (PACs), were identified for the firsttime in the urine of healthy volunteers after taking the new cranberry formulation”.
Serena Tongiani will present the last clinical evidences about ANTHOCRAN® PHYTOSOME™ at invitality on November 23rd.
Indena’s RELISSATM – MELISSA PHYTOSOME™ is a new standardized, botanical ingredient clinicallyvalidated as support to emotional and sleep health: a new way to balance mood and manage stress.
Based on the formulation of lemon balm extract from Melissa officinalis, it’s standardized inhydroxycinnamic acids (17-23% by HPLC) and analyzed for rosmarinic acid content. RELISSA TM –MELISSA PHYTOSOME™ is formulated with Indena’s Phytosome™ technology, which optimizes its
biological performances turning a good ingredient (Melissa officinalis) into a great ingredient.
Scientific evidences confirms that RELISSATM – MELISSA PHYTOSOME™ gives 24 hours of wellbeing,
activating a virtuous circle: sleeping better causes positive thoughts and feelings, which allows to keep
stress and anxiety under control. This means having a better mood and a better quality of life. As aresults, awakings are powerful, without any sign of dizziness or drowsiness.
Moreover, RELISSATM – MELISSA PHYTOSOME™ has good interaction with microbiota, has enhanced
effect on physiological GABA pathway, is efficacious for radical scavenging and has high tolerability.
INDENA’S COMMITMENT ON SUSTAINABILITY: THE IMPORTANCE OF THE SUPPLY CHAIN MANAGEMENTIn-vitality will also be the occasion to share with stakeholders Indena’s vision on sustainability, andspecifically on supply chain management. Renato Iguera, Medicinal Plants Purchasing Manager atIndena and President of Assoerbe (the only Italian traders association representing the sector ofBotanicals and their derivatives for use in health and wellness products), will make a presentation
focused on that topic.

“The sustainability of wild plant species’ supply chains is increasingly at the center of attention, also due
to greater sensitivity of consumers and of regulatory authorities – explains Iguera -. The peculiarity ofthese supply chains represents a challenge for companies and it is important to understand which tools
and actions are available for an effective risk analysis and to guarantee sustainable and certified supplychains”.
ATTEND INDENA’S PRESENTATIONS ON NOVEMBER 23RD, ARENA SEMINARI
At 10:10 am: ANTHOCRAN® PHYTOSOME™: nuove evidenze di attività per la salute delle vieurinarie
Speaker: Serena Tongiani Chief Portfolio Officer at Indena
At 2.30 pm: Lo sfruttamento (in)sostenibile delle piante officinali selvatiche
Speaker: Renato Iguera, Presidente Assoerbe, Medicinal Plants Purchasing Manager at Indena
VISIT INDENA AT IN-VITALITY 2023: STAND 261

22-23 November 2023 – Allianz MiCo Milano Congressi, Milan Italy

Indena is the leading company dedicated to the identification, development and production of high quality active
principles derived from plants, for use in the pharmaceutical and health food industries. Backed up by a century ofbotanical experience, the company owns 100 patent families, has published more than 1000 scientific studies andco- operates with the world’s most prestigious universities and private research institutions. Indena employs over
900 staff, investing a significant amount of its annual turnover in research, making this activity the key to its
success. Headquartered in Milan, Indena has 4 production sites and 5 international branches throughout theworld and manages sales in more than 80 countries. The company's experts communicate and interact constantlywith the major international regulatory authorities and cooperate on the update of all the main pharmacopoeias.
CDMO activities are the priority in Indena’s strategic vision. Today, Indena has a multipurpose GMP plant
equipped with reactor ranging from 250 lt to 10,000 lt (Stainless Stell, Hastelloy, Glass-lined); a kilo lab LK2 tooffer different capacities for products at the highest containment level (OEL 20 ng/m3 or OEB5); two spray dryers,
large and a mid-size, working with organic solvents; a 20-liter hydrogenator being complemented by a 250-literhydrogenator (ready at the end of 2023) to satisfy a wider demand for this kind of chemistry.
www.indena.com

Indena press contacts
bcw-burson cohn & wolfe - Luisa Cavagnera
luisa.cavagnera@bcw-global.com
Ph: +39.349.7665890