Publications (English peer-revied papers) Shinji Nagahiro
1.

Nagahiro S, Tada Y, Satomi J, Kinouchi T, Kuwayama K, Yagi K, Nakajima K，Matsushita N,
Miyamoto T, Yamaguchi T, Shimada K, Korai M, Mure H, Okayama Y, Abe T, Harada M,
Kitazato KT, Kanematsu Y, Treatment of unruptured cerebral aneurysms with themineralocorticoid receptor blocker eplerenone –Pilot study, Journal of Stroke andCerebrovascular Diseases, 20182.

Okazaki T, Nakagawa H, Hayase H, Irie S, Inagaki T, Saito O, Yamashina M, Nagahiro S, Saito
K, Idiopathic and chronic epidural hematoma in the lumbar spine: A case report and review ofliteratures, Neurol Med Chir (Tokyo), 58, 138-144, 20183.

Kageji T, Mizobuchi Y, Nakajima K, Nagahiro S, Postoperative Hematoma Requiring
Recraniotomy in 1149 Consecutive Patients with Intracranial Tumors, Operative Neurosurgery,
13(3), 392-397, 20174.

Shiba I, Kouzaki R, Yamada H, Endo Y, Takino T, Sato H, Kitazato K, Kageji T, Nagahiro S, Uto
Y, Design and synthesis of novel anti-metastatic hypoxic cytotoxin TX-2137 targeting AKT kinase.
Anticancer Res 37(7), 3877-3883, 2017

5.

Ganbold M, Harada M, Khashbat D, Abe T, Kageji T, Nagahiro S, Differences In High-Intensity
Signal Volume Between Arterial Spin Labeling And Contrast-Enhanced T1-Weighted Imaging
May Be Useful For Differentiating Glioblastoma From Brain Metastasis. J Med Invest 64(1.2),
58-63, 2017

6.

Davis GA, Ellenbogen RG, Bailes J, Cantu RC, Johnston KM, Manley GT, Nagahiro S, Sills A,
Tator CH, McCrory P, The Berlin international consensus meeting on concussion in sport.
Neurosurgery 0: 1-5, 2017

7.

McCrory P, Meeuwisse W, Dvorak J, Aubry M, Bailes J, Broglio S, Cantu RC, Cassidy D,
Echemendia RJ, Castellani RJ, Davis GA, Ellenbogen R, Emery C, Engebretsen L, FeddermannDemont N, Giza CC, Guskiewicz KM, Herring S, Iverson GL, Johnston KM, Kissick J, Kutcher
J, Leddy JJ, Maddocks D, Makdissi M, Manley GT, McCrea M, Meehan WP, Nagahiro S,
Patricios J, Putukian M, Schneider KJ, Sills A, Tator CH, Turner M, Vos PE.. Consensus statementon concussion in sport-the 5th international conference on concussion in sport held in Berlin,
October 2016. Br J Sports Med 0, 1-10, 2017

8.

Emery CA, Black AM, Kolstad A, Martinez G, Nettel-Aguirre A, Engebretsen L, Johnston K,
Kissick J, Maddocks D, Tator C, Aubry M, Dvorák J, Nagahiro S, Schneider K, What strategies
can be used to effectively reduce the risk of concussion in sport? Br J Sports Med 51(12), 978984, 20179.

Okazaki T, Nakagawa H, Yagi K, Hayase H, Nagahiro S, Saito K, Bone scintigraphy for the1

diagnosis of the responsible level of osteoporotic vertebral compression fractures in percutaneous
balloon kyphoplasty. Clin Neurol Neurosurg 152, 23-27, 2017
10. Uehara T, Minematsu K, Ohara T, Kimura K, Okada Y, Hasegawa Y, Tanahashi N, Suzuki A,
Takagi S, Nakagawara J, Arii K, Nagahiro S, Ogasawara K, Uchiyama S, Matsumoto M, Iihara
K, Toyoda K, PROMISE-TIA study Investigators. Incidence, predictors, and etiology ofsubsequent ischemic stroke within one year after transient ischemic attack. Int J Stroke 12(1), 8489, 2017
11. Yamamoto N, Satomi J, Yamamoto Y, Izumi Y, Nagahiro S, Kaji R, Usefulness of 3-Tesla
magnetic resonance arterial spin-labeled imaging for diagnosis of cranial dural arteriovenous
fistula. J Neurol Sci 372, 428-432, 201712. Yagi K, Nakagawa H, Okazaki T, Irie S, Inagaki T, Saito O, Nagahiro S, Saito K, Noninfectious
prevertebral soft-tissue inflammation and hematoma eliciting swelling after anterior cervicaldiscectomy and fusion. J Neurosurg Spine 26(4), 459-465, 2017
13. Yamamoto N, Satomi J, Yamamoto Y, Shono K, Kanematsu Y, Izumi Y, Nagahiro S, Kaji R, Risk
Factors of Neurological Deterioration in Patients with Cerebral Infarction due to Large-Artery
Atherosclerosis. J Stroke Cerebrovasc Dis 26(8), 1801-1806, 2017
14. Mizobuchi Y, Muramatsu K, Ohtani M, Satomi J, Fushimi K, Matsuda S, Nagahiro S, The current
status of microvascular decompression for the treatment of hemifacial spasm in Japan: An analysisof 2907 patients using the Japanese diagnosis procedure combination database. Neurol Med Chir
(Tokyo) 57(4), 184-190, 2017
15. Kanematsu Y, Satomi J, Kuwayama K, Yamaguchi I, Yoshioka S, Kinouchi T, Tada Y, Yamamoto
N, Matsubara S, Satoh K, Nagahiro S, Treatment Outcome of Carotid Artery Stenting Underwent
within 14 Days of Stroke Onset - Consideration of Safety and Efficacy of Urgent Carotid Artery
Stenting for Neurologically Progressing Patients. Neurol Med Chir (Tokyo) 57(6), 278-283, 201716. Sogabe S, Satomi J, Tada Y, Kanematsu Y, Kuwayama K, Yagi K, Yoshioka S, Mizobuchi Y, Mure
H, Yamaguchi I, Abe T, Yamamoto N, Kitazato KT, Kaji R, Harada M, Nagahiro S, Intra-arterial
high signals on arterial spin labeling perfusion images predict the occluded internal carotid arterysegment. Neuroradiology 59(6), 587-595, 2017
17. Aoki J, Kimura K, Morita N, Harada M, Metoki N, Tateishi Y, Todo K, Yamagami H, Hayashi K,
Terasawa Y, Fujita K, Yamamoto N, Deguchi I, Tanahashi N, Inoue T, Iwanaga T, Kaneko N,
Mitsumura H, Iguchi Y, Ueno Y, Kuramoto Y, Ogata T, Fujimoto S, Yokoyama M, Nagahiro S,
YAMATO Study Investigators. YAMATO study (Tissue-type plasminogen activator andedaravone combination therapy). Stroke 48(3), 712-719, 201718. Shono K, Satomi J, Tada Y, Kanematsu Y, Yamamoto N, Izumi Y, Kaji R, Harada M, Nagahiro S,
2

Optimal timing of diffusion-weightd imaging to avoid false-negative findings in patients withtransient ischemic attack. Stroke 48(7), 1990-1992, 2017
19. Kageji T, Miyamoto T, Kotani Y, Kaji T, Bando Y, Mizobuchi Y, Nakajima K, Nagahiro S,
Congenital craniopharyngioma treated by radical surgery: case report and review of the literature.
Childs Nerv Syst 33(2), 357-362, 201720. Yagi K, Nakagawa H, Mure H, Okita S, Nagahiro S, Cryptic Recanalization of Chronic Vertebral
Artery Occlusion by Head Rotation. J Stroke Cerebrovasc Dis 26(4), e60-e61, 2017
21. Yamaguchi I, Satomi J, Yamamoto N, Yoshioka S, Tada Y, Yagi1 K, Kanematsu Y, Nagahiro S,
Coexistence of quasi-moyamoya disease and POEMS syndrome in a Patient with Intracranial
Hemorrhage: A Case Report and Literature Review. NMC Case Report Journal 4(1), 5-9, 2017
22. Takahashi JC, Funaki T, Houkin K, Inoue T, Ogasawara K, Nakagawara J, Kuroda S, Yamada K,
Miyamoto S, JAM Trial Investigators. Significance of the Hemorrhagic Site for Recurrent
Bleeding: Prespecified Analysis in the Japan Adult Moyamoya Trial.Stroke 47(1), 37-43, 201623. Yamamoto N, Satomi J, Harada M, Izumi Y, Nagahiro S, Kaji R. Is the susceptibility vessel signon 3-tesla magnetic resonance T2*-weighted imaging a useful tool to predict recanalization in
intravenous tissue plasminogenn activator? Clin Neuroradiol 26(3), 317-323, 201624. Miyamoto T, Kung DK, Kitazato KT, Yagi K, Shimada K, Tada Y, Korai M, Kurashiki Y, Kinouchi
T, Kanematsu Y, Satomi J, Hashimoto T, Nagahiro S, Site-specific elevation of interleukin-1βandmatrix metalloproteinase-9 in the Willis circle by hemodynamic changes is associated withrupture in a novel rat cerebral aneurysm model. J Cereb Blood Flow Metab Epub ahead of print(PMID: 27798272 DOI: 10.1177/0271678X16675369), 2016
25. Korai M, Kitazato KT, Tada Y, Miyamoto T, Shimada K, Matsushita N, Kanematsu Y, Satomi J,
Hashimoto T, Nagahiro S, Hyperhomocysteinemia induced by excessive methionine intake
promotes rupture of cerebral aneurysms in ovariectomized rats. J Neuroinflammation 13(1), 165,
2016
26. Bando M, Yamada H, Kusunose K, Fukuda D, Amano R, Tamai R, Torii Y, Hirata Y, Nishio S,
Satomi J, Nagahiro S, Sata M . Noninvasive quantitative tissue characterization of carotid plaques
using color-coded mapping based on ultrasound integrated backscatter. JACC Cardiovasc
Imaging 9(5), 625-627, 2016
27. Majigsuren M, Abe T, Kageji T, Matsuzaki K, Takeuchi M, Iwamoto S, Otomi Y, Uyama N,
Nagahiro S, Harada M. Comparison of brain tumor contrast-enhancement on T1-CUBE and 3DSPGR images. Magn Reson Med Sci 15(1), 34-40, 201628. Satomi J, Hadeishi H, Yoshida Y, Suzuki A, Nagahiro S, Histopathological findings in brains ofpatients who died in the acute stage of poor-grade subarachnoid hemorrhage. Neurol Med Chir
3

(Tokyo) 56(12), 766-770, 2016
29. Kageji T, Obata F, Oka H, Kanematsu Y, Tabata R, Tani K, Bando H, Nagahiro S, Drip-and-ship
thrombolytic therapy supported by the telestroke system for acute ischemic stroke patients living
in medically under-served areas. Neurol Med Chir (Tokyo). 56(12), 753-758, 2016
30. Ogino H, Hanibuchi M, Takizawa H, Sakiyama S, Sumiomo H, Iwamoto S, Ikushima H,
Nakajima K. Nagahiro S, Yamago T,

Toyoda Y, Bando Y. Nishioka Y. Primary pulmonary

synovial sarcoma showing a prolonged survival with multimodality therapy. Intern Med 55(4),381-387, 201631. Mizobuchi Y, Shouno K, Nakajima K, Nagahiro S, Trigeminal neuralgia caused by fibrous bands:
case illustration. J Neurosurg 124, 186-187, 201632. Mizobuchi Y, Shouno K, Nakajima K, Nagahiro S, Trigeminal neuralgia caused by fibrous bands:
case illustration. J Neurosurg 124(1), 186-187, 2016
33. Yamamoto Y, Okazaki T, Yoda K, Tada Y, Nagahiro S, Successful emergency carotid
endarterectomy after thrombolysis with intravenous recombinant tissue-type plasminogenactivator. The Journal of Medical Investigation 63(3-4), 300-304, 201634. Morigaki R, Mure H, Kaji R, Nagahiro S, Goto S, Therapeutic perspective on tardive syndrome
with special reference to deep brain stimulation. Front Psychiatry 7, 207, 201635. Mizobuchi Y, Nagahiro S, A review of sport-related head injuries. Korean J Neurotrauma 12(1),1-5, 2016
36. Kageji T, Sogabe S, Mizobuchi Y, Nakajima K, Nagahiro S, Nakagawa Y, Radiation-induced
meningiomas after BNCT in patients with malignant glioma. Appl Radiat Isot 106, 256-259, 201537. Sumiyoshi M, Kitazato KT, Yagi K, Miyamoto T, Kurashiki Y, Matsushita N, Kinouchi T,
Kuwayama K, Satomi J, Nagahiro S, The accumulation of brain water-free sodium is associatedwith ischemic damage independent of the blood pressure in female rats. Brain Res 1616, 37-44,
2015
38. Minagawa T, Tamura A, Ichihara T, Hisaka Y, Nagahiro S, Increasing upper-limb joint range of
motion in post-stroke hemiplegic patients by daily hair-brushing. British J Neuroscience Nursing
11(3), 201539. Hara K, Kageji T, Mizobuchi Y, Kitazato KT, Okazaki T, Fujihara T, Nakajima K, Mure H,
Kuwayama K, Hara T, Nagahiro S, Blocking of the interaction between Wnt progeins and theircoreceptors contributes to the anti-tumor effects of adenovirus-mediated DKK3 in glioblastoma.
Cancer Lett 356, 496-505, 201540. Hama Y, Uehara T, Ohara T, Kimura K, Okada Y, Hasegawa Y, Tanahashi N, Suzuki A, Takagi S,
4Nakagawara J, Arii K, Nagahiro S, Ogasawara K, Nagao T, Uchiyama S, Matsumoto M, Iihara K,
Toyoda K, Minematsu K, Clinical Characteristics of Transient Ischemic Attack Patients with
Atrial Fibrillation: AnalysEs of a Multicenter Retrospective Study. Cerebrovasc Dis Extra 5(2),84-90, 201541. Hosomi N, Nagai Y, Kohriyama T, Ohtsuki T, Aoki S, Nezu T, Maruyama H, Sunami N, Yokota
C, Kitagawa K, Terayama Y, Takagi M, Ibayashi S, Nakamura M, Origasa H, Fukushima M, Mori
E, Minematsu K, Uchiyama S, Shinohara Y, Yamaguchi T, Matsumoto M; J-STARS Collaborators,
The Japan Statin Treatment Against Recurrent Stroke (J-STARS): A Multicenter, Randomized,
Open-label, Parallel-group Study. EBioMedicine 2(9), 1071-1078, 201542. Shimada K, Furukawa H, Wada K, Wei Y, Tada Y, Kuwabara A, Shikata F, Kanematsu Y, Lawton
MT, Kitazato KT, Nagahiro S, Hashimoto T, Angiotensin-(1-7) protects against the developmentof aneurysmal subarachnoid hemorrhage in mice. J Cereb Blood Flow Metab 35, 1163-1168, 2015
43. Yamamoto N, Satomi J, Yuki Y, Furukawa T, Tada Y,Harada M, Nagahiro S, Kaji R, The
susceptibility vessel sign containing two compositions on 3-tesla T2*-weighted image and single
corticosubcortical infarct on diffusion-weighted image are associated with cardioembolic stroke.
J Neurol Sci 359(1-2), 141-145, 201544. Satomi J, Ghaibeh AA, Moriguchi H, Nagahiro S, Predictability of the future development of
aggressive behavior of cranial dural arteriovenous fistulas based on decision tree analysis. J
Neurosurg 123, 86-90, 2015
45. Tada Y, Yagi K, Uno M Matsushita N, Kanematsu Y, Kuwayama K, Shimada K, Nishi K,
Hirasawa M, Satomi J, Kitazato KT, Kageji T, Matsumura E, Nagahiro S, Improvement of plasma
biomarkers after switching stroke patients from other angiotensin II type I receptor blockers toolmesartan. J Stroke Cerebrovasc Dis 24, 1487-1492, 201546. Sumiyoshi M, Satomi J, Kitazato KT, Yagi K, Kurashiki Y, Korai M, Miyamoto T, Kuwayama K,
Nagahiro S, PPARγ-dependent- and -independent inhibition of the HMGB1/TLR9 Pathway by
eicosapentaenoic acid attenuates ischemic brain damage in ovariectomized rats. J Stroke
Cerebrovasc Dis 24(6), 1187-1195, 2015
47. Yamamoto N, Satomi S, Izumi Y, Yuki Y, Nagahiro S, Ryuji K, Predictors of a favorable outcome
after recanalization in patients with cerebral major vessel occlusion. J Stroke Cerebrovasc Dis24(12), 2793-2799, 2015
48. Abe T, Mizobuchi Y, Sako W, Irahara S, Otomi Y, Obama Y, Nakajima K, Khashbat D, Majigsuren
M, Kageji T, Nagahiro S, Harada M, Clinical Significance of Discrepancy between Arterial Spin
Labeling Images and Contrast-enhanced Images in the Diagnosis of Brain Tumors. Magn Reson
Med Sci 14(4), 313-319, 20155

49. Yagi K, Irie S, Inagaki T, Ishii Y, Saito O, Lee T, Nakagawa H, Saito K, Nagahiro S, Intraoperativearachnoid plasty has possibility to prevent chronic subdural hematomas after surgery for
unruptured cerebral aneurysms. Neurol Med Chir 55, 493-497, 2015
50. Kataoka H, Miyamoto S, Ogasawara K, Iihara K, Takahashi JC, Nakagawara J, Inoue T, Mori E,
Ogawa K, On Behalf of the JET-2 Investigators, Results of prospective cohort study on
symptomatic cerebrovascular occlusive disease showing mild hemodynamic compromise[Japanese extracranial-intracranial bypass trial (JET)-2 study]. Neurol Med Chir 55, 460-468,
2015
51. Etminan N, Brown RD Jr, Beseoglu K, Juvela S, Raymond J, Morita A, Torner JC, Derdeyn CP,
Raabe A, Mocco J, Korja M, Abdulazim A, Amin-Hanjani S, Al-Shahi Salman R, Barrow DL,
Bederson J, Bonafe A, Dumont AS, Fiorella DJ, Gruber A, Hankey GJ, Hasan DM, Hoh BL,
Jabbour P, Kasuya H, Kelly ME, Kirkpatrick PJ, Knuckey N, Koivisto T, Krings T, Lawton MT,
Marotta TR, Mayer SA, Mee E, Pereira VM, Molyneux A, Morgan MK, Mori K, Murayama Y,
Nagahiro S, Nakayama N, Niemelä M, Ogilvy CS, Pierot L, Rabinstein AA, Roos YB, Rinne J,
Rosenwasser RH, Ronkainen A, Schaller K, Seifert V, Solomon RA, Spears J, Steiger HJ,
Vergouwen MD, Wanke I, Wermer MJ, Wong GK, Wong JH, Zipfel GJ, Connolly ES Jr, Steinmetz
H, Lanzino G, Pasqualin A, Rüfenacht D, Vajkoczy P, McDougall C, Hänggi D, LeRoux P, Rinkel
GJ, Macdonald RL, The unruptured intracranial aneurysm treatment score: A multidisciplinaryconsensus. Neurology 85(10), 881-889, 2015
52. Abe T, Mizobuchi Y, Nakajima K, Otomi Y, Irahara S, Obama Y, Majigsuren M, Khashbat D,
Kageji T, Nagahiro S, Harada M, Diagnosis of brain tumors using dynamic contrast-enhanced
perfusion imaging with a short acquisition time. Springerplus 24(4), 88, 201553. Shimada K, Furukawa H, Wada K, Korai M, Wei Y, Tada Y, Kuwahara A, Shikata F, Kitazato KT,
Nagahiro S, Lawton MT, Hashimoto T. Protective role of peroxisome proliferator-activatedreceptor-γ in the development of intracranial aneurysm rupture. Stroke 46, 1664-1672, 2015
54. Mori E, Minematsu K, Nakagawara J, Hasegawa Y, Nagahiro S, Okada Y, Truelsen T, Lindsten
A, Ogawa A, Yamaguchi T, on behalf of DIAS-J Investigators. Safety and tolerability ofdesmoteplase within 3 to 9 hours after symptoms onset in Japanese patients with ischemic stroke.
Stroke 46(9), 2549-2554, 2015
55. Yamamoto N, Satomi J, Tada Y, Harada M, Izumi Y, Nagahiro S, Kaji R. Two-layered
susceptibility vessel sign on 3-tesla T2*-weighted imaging is a presictive biomarker of stroke
subtype. Stroke 46, 269-271, 2015
56. Yagi K, Lidington D, Wan H, Fares JC, Meissner A, Sumiyoshi M, Ai J, Folz WD, Nedospasov
SA, Offermanns S, Nagahiro S, Macdonald RL, Bolz SS. Therapeutically targeting tumor necrosis
factor-a/sphingosine-1-phophate signaling corrects myogenic reactivity in subarachnoid
6hemorrhage. Stroke 46, 2260-2270, 2015
57. Nakajima N, Nagahiro S, Satomi J, Tada Y, Nakajima K, Sogabe S, Hanaoka M, Matsubara S,
Uno M, Satoh K. Prevention of retrograde blood flow into large or giant internal carotid arteryaneurysms by endovascular coil embolization with high-flow bypass: surgical technique and longterm results. World Neurosurg 83, 1127-1134, 2015
58. Goto S, Morigaki R, Okita S, Nagahiro S, Kaji R. Development of a highly sensitive
immunohistochemical method to detect neurochemical molecules in formalin-fixed and paraffinembedded tissues from autopsied human brains. Front Neuroanat 9(22), 201559. Mizobuchi Y, Kageji T, Yamaguchi T, Nagahiro S, Craniotomy for cerebellar hemangioblastoma
excision in a patient with von Hipel-Lindau disease complicated by uncontrolled hypertension
due to pheochromocytoma. Int J Surg Case Rep 17, 96-99, 2015
60. Yoshioka S, Kuwayama K, Satomi J, Nagahiro S, Transarterial N-Butyl-2-cyanoacrylate
embolization of an intraosseous dural arteriovenous fistula associated with acute epidural
hematoma: technical case report. Neurosurgery 11(3), 468-471, 2015
61. Yamamoto N, Satomi J, Tada Y, Harada M, Izumi Y, Nagahiro S, Kaji R, Two-layered
susceptibility vessel sign on 3-tesla T2*-weighted imaging is a presictive biomarker of stroke
subtype, Stroke, 46, 2015
62. Yagi K, Lidington D, Wan H, Fares JC, Meissner A, Sumiyoshi M, Ai J, Folz WD, Nedospasov
SA, Offermanns S, Nagahiro S, Macdonald RL, Bolz SS, Therapeutically targeting tumor necrosis
factor-a/sphingosine-1-phophate signaling corrects myogenic reactivity in subarachnoid
hemorrhage, Stroke, 46: 2260-2270, 201563. Hara K, Kageji T, Mizobuchi Y, Kitazato KT, Okazaki T, Fujihara T, Nakajima K, Mure H,
Kuwayama K, Hara T, Nagahiro S, Blocking of the interaction between Wnt proteins and theirco-receptors contributes to the anti-tumor effects of adenovirus-mediated DKK3 in glioblastoma,
Cancer Letters, 356: 496-505, 2015
64. Tada Y, Wada K, Shimada K, Makino H, Liang EI, Murakami S, Kudo M, Kitazato KT, Nagahiro
S, Hashimoto T, Roles of hypertension in the rupture of intracranial aneurysms, Stroke, 45: 579586, 2014
65. Kageji T, Mizobuchi Y, Nagahiro S, Nakagawa Y, Kumada H, Correlation between radiation doseand histopathological findings in patients with glioblastoma treated with boron neutron capture
therapy (BNCT), Applied Radiation and Isotopes, 88: 20-22, 20147

66. Okazaki T, Yamamoto Y, Yoda K, Nagahiro S, The ratio of D-dimer to brain natriuretic peptide
may help to differentiate between cerebral infarction with and without acute aortic dissection,
Journal of the Neurological Sciences, 340：133-138, 2014
67. Matsubara S, Satoh K, Satomi J, Shigekiyo T, Kinouchi T, Miyake H, Nagahiro S, Acquired pial
and dural arteriovenous fistulae following superior sagittal sinus theombosis in patients withprotein S deficiency: A report of two cases, Neurol Med Chir (Tokyo), 54: 245-252, 2014
68. Tada Y, Wada K, Shimada K, Makino H, Liang EI, Murakami S, Kudo M, Shikata F, Silva RAP,
Kitazato KT, Hasan DM, Kanematsu Y, Nagahiro S, Hashimoto T, Estrogen protects against
intracranial aneurysm rupture in ovariectomized mice, Hypertension, 63: 1339-1344, 201469. Etminan N, Beseoglu K, Barrow DL, Bedersonn J, Brown RD Jr, Connolly ES Jr, Derdeyn CP, H
nggi D, Hasan D, Juvela S, Kasuya H, Kirkpatrick PJ, Knuckey N, Koivisto T, Lanzino G, Lawton
MT, LeRoux P, McDougall CG, Mee E, Mocco J, Molyneux A, Morgan MK, Mori K, Morita A,
Murayama Y, Nagahiro S, Pasqualin A, Raabe A, Raymond J, Rinkel GJE, R fenacht D, Seifert V,
Spears J, Steiger HJ, Steinmetz H, Torner JC, Vajkoczy P, Wanke I, Wong GKC, Wong JH,
MacDonald RL, Multidisciplinary consensus on assessment of unruptured intracranial aneurysms:
Proposal of an international research group, Stroke, 45: 1523-1530, 2014
70. Miyamoto S, Miyamoto S, Yoshimoto T, Hashimoto N, Okada Y, Tsuji, I, Tominaga T,
Nakagawara J, Takahashi JC, on behalf of the JAM Trial Investigators; Yamada K, Tomata Y,
Fukui T, Fukuuchi Y, Ohmoto T, Kuwabara Y, Nagata I, Ono J, Machida T, Sakakibara R, Yamane
K, Okita S, Iwama T, Kaku Y, Saito N, Fukuyama H, Houkin K, Kuroda S, Yabe I, Moriwaka F,
Ogawa A, Ogasawara K, Yoshida K, Fujii K, Yamada M, Sato K, Akutsu T, Yamagata S, Takeuchi
S, Hayashi K, Horie N, Yamada K, Osato T, Watanabe T, Honjo K, Sako K, Nakase H, Kawaguchi
S, Nisimura F, Yamao J, Naritomi H, Inoue T, Abe H, Suzuki A, Ishikawa T, Akiyama Y, Suenaga
T, Fujimura M, Nagahiro S, Uno M, Nishi K, Satomi J, Okada Y, Kawashima A, Yamaguchi K,
Tsutsumi Y, Effect of extracranial-intracranial bypass for patients with hemorrhagic moyamoya
disease - Results of the Japan adult moyamoya trial-, Stroke, 45: 1415-1421, 2014
71. Tada Y, Satomi J, Kanematsu Y, Kuwayama K, Matsushita N, Abe T, Harada M, Nagahiro S, Postischemic hyperperfusion after clipping of a reptured internal carotid-posterior communicating art
ery aneurysm under suction decomperession, Interdisciplinary Neurosurgery: Advanced
Techniques and Case Management, 1: 62-65, 201472. Hirasawa M, Mure H, Toi H, Nagahiro S, Surgical results of lumbor interbody fusion using
calcium phosphote cement, Neurol Med Chirur, 54: 722-726, 20148

73. Kageji T, Nagahiro S, Mizobuchi Y, Matsuzaki K, Nakagawa Y, Kumada H, Boron neutron
capture therapy (BNCT) for newly-diagnosed glioblastoma: Comparison of clinical results
obtained with BNCT and conventional treatment, The Journal of Medical Investigation, 61: 254263, 2014
74. Kageji T, Nagahiro S, Mizobuchi Y, Matsuzaki K, Nakagawa Y, Kumada H, Boron neutron
capture therapy (BNCT) for newly-diagnosed glioblastoma: Comparison of clinical results
obtained with BNCT and conventional treatment, J Med Invest, 61: 254-263, 2014
75. Kageji T, Mizobuchi Y, Nagahiro S, Nakagawa Y, Kumada H, Correlation between rediatio doseand histopathological findings in patients with glioblastoma treated with boron neutron capture
therapy (BNCT), Appl Radiat Isot, 88: 20-22, 2014
76. Tada Y, Satomi J, Kuwayama K, Sogabe S, Fujita K, Yamamoto N, Kaji R, Harada M, Nagahiro
S, Intra-arterial signal on arterialspin labeling perfusion MRI to identigy the presence of acutemiddle cerebral occlusion, Cerebrovascular Disease, 9: 191-196, 2014
77. Yamamoto N, Terasawa Y, Satomi J, Sakai W, Harada M, Izumi Y, Nagahiro S, Kaji R, Predictorsof neurologic deterioration in patients with small-vessel occlusion and infarcts in the territory of
perforating arteries, J Stroke Cerebrovascular Disease, 23: 2151-2155, 2014
78. Yamamoto N, Satomi J, Harada M, Izumi Y, Nagahiro S, Kaji R, Is the susceptibility vessel signon 3-tesla magnetic resonance T2*-weighted imaging a useful tool to predict recanalization in
intravenous tissue plasminogenn activator?, Clin Neuroradiol, 2014
79. Fujinami J, Uehara T, Kimura K, Okada Y, Hasegawa Y, Tanahashi N, Suzuki A, Takagi S,
Nakagawara J, Arii K, Nagahiro S, Ogasawara K, Nagao T, Uchiyama S, Matsumoto M, Iihara K,
Minematsu K, Incidence and predictors of ischemic stroke events during hospitalization inpatients with transient ischemic attack, Cerebrovascular Disease, 37: 330-335, 2014
80. Uehara T, Kimura K, Okada Y, Hasegawa Y, Tanahashi N, Suzuki A, Takagi S, Nagakagawa J,
Arii K, Nagahiro S, Ogasawara K, Nagao T, Uchiyama S, Matsumoto M, Iihara K, Minematsu K,
Factors associated with onset-to-door time in patients with transient ischemic attack admitted to
stroke centers, Stroke, 45: 611-613, 2014
81. Tanaka K, Uehara T, Kimura K, Okada Y, Hasegawa Y, Tanahashi N, Suzuki A, Takagi S,
Nakagawara J, Arii K, Nagahiro S, Ogasawara K, Nagao T, Uchiyama S, Matsumoto M, Iihara K,
Toyoda K, Minematsu K, Features of patients with transient monocular blindness: a multicenter
retrospective study in Japan, J Stroke Cerebrovascular Disease, 23: e151-155, 20149

82. Mure H, Morigaki R, Koizumi H, Okita S, Kawarai T, Miyamoto R, Kaji R, Nagahiro S, Goto S,
Dedp brain stimulation of the thelamic ventral lateral anterior nucleus for DYT6 dystonia,
Stereotactic Functional Neurosurgery, 92: 393-396, 2014
83. Nagahiro S, Mizobuchi Y, Current topics in sports-related head injuries: A review , Neurol Med
Chir, 54: 878-886, 2014
84. Tada Y, Makino H, Furukawa H, Shimada K, Wada K, Liang EI, Murakami S, Kudo M, Kung DK,
Kitazato KT, Nagahiro S, Lawton MT, Hashimoto T, Roles of estrogen in the formation of
intracranial aneurysms in ovariectomized female mice, Neurosurgery, 75: 690-695, 2014
85. Terasawa Y, Yamamoto N, Morigaki R, Fujita K, Izumi Y, Satomi J, Harada M, Nagahiro S, Kaji
R, Brush sign on 3-T t2*-weighted MRI as a potential predictor of hemorrhagic transformation
after tissue plasminogen activator therapy, Stroke 45: 274-276, 2014
86. Tada Y, Satomi J, Kanematsu Y, Kuwayama K, Matsushita N, Abe T, Harada M, Nagahiro S, Postischemic hyperperfusion after clipping of a reptured internal carotid-posterior communicatingartery aneurysm under suction decomperession, Interdisciplinary, Neurosurgery: Advanced
Techniques and Case Management, 1: 62-65, 2014
87. Okazaki T, Kageji T, Mizobuchi Y, Miyamoto T, Nagahiro S, Nine-year interval recurrence after
treatment of boron neutron capture therapy in a patient with glioblastoma: A case report, Applied
Radiation and Isotopes, 88: 28-31, 2014
88. Yamamoto N, Terasawa Y, Satomi J, Morigaki R, Fujita K, Harada M, Izumi Y, Nagahiro S, Kaji
R, Reversibility of ischemic findings on 3-tesla magnetic resonance T2*-weighted image after
recanalization, The Journal of Medical Investigation, 61: 190-196, 201489. Inoue N, Watanabe H, Okamura K, Sakaki M, Kageji T, Nagahiro S, Kagami S, Atypical teratoid
rhabdoid tumor in the cavernous sinus of a toddler presenting with ovulomotor nerve palsy, Childs
Nerv Syst, 30: 1463-1468, 2014
90. Goto S, Kawarai T, Morigaki R, Okita S, Koizumi H, Nagahiro S, Munoz EL, Lee LV, Kaji R,
Defects in the striatal neuropeptide Y system in X-linked dystonia-parkinsonism, Brain, 136:
1555-1567, 2013
91. Yamamura Y, Morigaki R, Kasahara J, Yokoyama H, Tanabe A, Okita S, Koizumi H. Nagahiro S,
Kaji R, Goto S, Dopamine signaling negatively regulates striatal phosphorylation of Cdk5 attyrosine 15 in mice, Frontiers in Cellular Neuroscience, 7, 12: 1-10, 201310

92. Fujita K, Sakai W, Harada M, Sakaki M, Mure H, Nagahiro S, Izumi Y, Kaji R, Basal ganglia
hyperintensity on T1-weighted imaging of a patient with central nervous system matestasis
producing carcinc, Internal Medicine, 52: 381-383, 2013
93. Kamitani T, Nimura Y, Nagahiro S, Miyazaki S, Tomatsu T, Catastrophic head and neck injuries
in Judo players in Japan from 2003 to 2010, The American Journal of Sports Medicine, 2013
94. Morita N, Harada M, Satomi J, Terasawa Y, Kaji R, Nagahiro S, Frequency of emerging positive
diffusion-weighted imaging in early repeat examinations at least 24h after transient ischemic
attacks, Neuroradiology, 55: 399-403, 2013
95. Koizumi H, Morigaki R, Okita S, Nagahiro S, Kaji R, Nakagawa M, Goto S, Response ofstriosomal opioid signaling to dopamine depletion in 6-hydroxydopamine-lesioned rat model ofParkinson’s disease: a potential compensatory role, Front Cell Neurosci, 17(7): 74, 2013
96. Miyagi T, Uehara T, Kimura K, Okada Y, Hasegawa Y, Tanahashi N, Suzuki A, Takagi S,
Nakagawara J, Arii K, Nagahiro S, Ogasawara K, Nagao T, Uchiyama S, Matsumoto M, Iihara K,
Toyoda K, Minematsu K, Features of patients with transient monocular blindness: a multicenter
retrospective study in Japan. Examination timing and lesion patterns in diffusion-weighted
magnetic resonance imaging of patients with classically defined transient ischemic attack,Cerebrovescular Disease, 22: e310-316, 2013
97. Morigaki R, Nakataki M, Kawarai T, Lee LV, Teleg RA, Tabuena MDP, Mure H, Sako W, Pasco
PMD, Nagahiro S, Iga J, Ohmori T,

Goto S, Kaji R, Depression in X-linked dystonia-

parkinsonism: A case-control study, Parkinsonism and Related Disorders, 19: 844-846, 2013
98. Nakajima K, Maekawa Y, Kataoka K, Ishifune C, Nishida J, Arimochi H, Kitamura A, Yoshimoto
T, Tomita S, Nagahiro S, Yasutomo K, The ARNT-STAT3 axis regulates the differentiation ofintestinal intraepithelial TCRαβ+CD8αα+cells, Nature Communications, 1-11, 2013

99. Yamamura Y, Morigaki R, Kasahara J, Yokoyama H, Tanabe A, Okita S, Koizumi H. Nagahiro S,
Kaji R, Goto S, Dopamine signaling negatively regulates striatal phosphorylation of Cdk5 attyrosine 15 in mice, Frontiers in Cellular Neuroscience, 7: 1-10, 2013100. Miyamoto R, Goto S, Sako W, Miyashiro A, Kim I, Escande F, Harada M, Morigaki R, Asanuma
K, Mizobuchi Y, Nagahiro S, Izumi Y, Kaji R, Generalized dystonia in a patient with a novel
mutation in the GLUD1 gene, Movement Disorders, 27(9): 1198-1199, 2012
101. Kinouchi T, Kitazato KT, Shimada K, Yagi K, Tada Y, Matsushita Y, Sumiyoshi M, Satomi J,
11

Kageji T, Nagahiro S, Activation of signal transducer and activator of transcription-3 by aperoxisome proliferator-activated receptor gamma agonist contributes to neuroprotection in theperi-infarct region after ischemia in oophorectomized rats, Stroke, 43: 478-483, 2012
102. Okazaki T, Kageji T, Kuwayama K, Kitazato KT, Mure H, Hara K, Morigaki R, Mizobuchi, Y,
Matsuzaki K, Nagahiro S, Up-regulation of endogenous PML induced by a combination ofinterferon-beta and temozolomide enhances p73/YAP-mediated apoptosis in glioblastoma,
Cancer Letters, 28: 199-207, 2012
103. Matsushita N, Kitazato KT, Tada Y, Sumiyoshi M, Shimada K, Yagi K, Kanematsu Y, Satomi J,
Nagahiro S, Increase in body Na+-to-water ratio is associated with cerebral aneurysm formationin oophorectomized rats, Hypertension, 60: 1309-1315, 2012
104. Morigaki R, Satomi J, Shikata E, Nagahiro S, Aneurysm of the lateral spinal artery: A case report,
Clinical Neurology and Neurosurgery, 114: 713-716, 2012
105. Okita S, Morigaki R, Koizumi H, Kaji R, Nagahiro S, Goto S, Cell type-specific localization of
optineurin in the striatal neurons of mice: Implications for neuronal vulnerability in huntington's
disease, Neurosciences, 202: 363-370, 2012
106. Bando Y, Takahashi T, Uehara H, Kageji T, Nagahiro S, Izumi K

Case Report: Autopsy caseof amebic granulomatous meningoencephalitis caused by Balamuthia mandrillaris in Japan,
Pathology International, 62: 418-423, 2012107. Bando Y, Takahashi T, Uehara H, Kageji T, Nagahiro S, Izumi K, Case Report: Autopsy case ofamebic granulomatous meningoencephalitis caused by Balamuthia mandrillaris in Japan,
Pathology International, 62: 418-423, 2012108. Kondo A, Date I, Endo S, Fujii K, Fujii Y, Fujimitsu T, Hasegawa M, Hatayama T, Hongo K,
Inoue T, Ishikawa M, Ito M, Kayama T, Kohmura E, Matsushima T, Munemoto S, Nagahiro S,
Ohno K, Okumura T, Ryu H, Shigeno T, Shirane R, Tagusagawa Y, Tanabe H, Yamada K,
Yamakami I, A proposal for standardized analysis of the results of microvascular decompression
for trigeminal neuralgia and hemifacial spasm, Acta Neurochir, 154: 773-778, 2012109. Hanaoka M, Matsubara S, Satoh K, Nagahiro S, Dural arteriovenous fistulae after cerebral
infarction: report of two cases, Neurosurgery, 68(2), ES75-ES80, 2011110. Morigaki R, Nagahiro S, Kaji R, Goto S, Currrent use of thalamic surgeries for treating movement
disorders, Justin L Song (Ed.), Thalamus: Anatomy, Functions and Disorders, New York, Nova
12

Science Publishers, Inc.: 1-31, 2011111. Morigaki R, Sako W, Okita S, Kasahara J, Yokoyama H, Nagahiro S, Kaji R, Goto S, Cyclindependent kinase 5 with phosphorylation of tyrosine 15 residue is enriched in striatal matrix
compartment in adult mice, Neuroscience, 189: 25-31, 2011112. Sako W, Morigaki R, Mizobuchi Y, Tsuzuki T, Ima H, Ushio Y, Nagahiro S, Kaji R, Goto S,
Bilateral pallidal deep brain stimulation in primary meige syndrome, Parkinsonism and Related
Disorders, 17: 123-125, 2011113. Sako W, Morigaki R, Okita S, Kasahara J, Yokoyama H, Nagahiro S, Kaji R, Goto S, Identificationand localization of a neuron-specific isoform of TAF1 in rat brain: implications forneuropathology of DYT3 dystonia, Neuroscience, 189: 100-107, 2011114. Shimada K, Kitazato KT, Kinouchi T, Yagi K, Tada Y, Satomi J, Kageji T, Nagahiro S, Activationof estrogen receptor-α and of angiotensin-converting enzyme 2 suppresses ischemic brain damage
in oophorectomized rats, Hypertension, 57: 1161-1166, 2011115. Tada Y, Kitazato KT, Yagi K, Shimada K, Matsushita N, Kinouchi T, Kanematsu Y, Satomi J,
Kageji T, Nagahiro S, Statins promote the growth of experimentally induced cerebral aneurysms
in estrogen-deficient rats, Stroke, 42: 2286-2293, 2011116. Kashihara M, Nakao S, Kawasaki J, Takata S, Nagahiro S, Kaji R, Yasui N, Long-term outcomeof severe stroke patients: Is the ADL status at discharge from a stroke center indicative of thelong-term outcome?, The Journal of Medical Investigation, 58: 227-234, 2011117. Tamura A, Ichihara T, Minagawa T, Kuwamura Y, Kondo H, Takata S, Yasui N, Nagahiro S,
Exercise intervention soon after stroke patient onset to prevent muscle atrophy, British Journal of
Neuroscience Nursing, 7: 574-579, 2011118. Kageji T, Mizobuchi Y, Nagahiro S, Nakagawa Y, Kumada H, Long-survivors of glioblastoma
treated with boron neutron capture therapy (BNCT), Applied Radiation and Isotopes, 69: 18001802, 2011119. Kageji T, Mizobuchi Y, Nagahiro S, Nakagawa Y, Kumada H, Clinical results of boron neutron
capture therapy (BNCT) for glioblastoma, Applied Radiation and Isotopes, 69: 1823-1825, 2011
120. Morigaki R, Nagahiro S, Kaji R, Goto S, Thalamic deep brain stimulation for Parkinson's Disease,
DIAGNOSIS AND TREATMENT OF PARKINSON'S DISEASE, ed by Abdul Quyyum Rana,13

2011, pp233-252
121. Nagahiro S, Revised organ transplant act and neurosurgeons, JMAJ, 54: 375-380, 2011122. Kageji T, Mizobuchi Y, Nagahiro S, Nakagawa Y, Kumada H, Boron neutron capture therapy
combined with fractionated photon irradiation for glioblastoma: A recursive partitioning analysis
of BNCT patients, Applied Radiation and Isotopes, 69: 1790-1792, 2011123. Nakajima N, Nagahiro S, Sano T, Satomi J, Tada Y, Yagi K, Kitazato KT, Satoh K. Kruppel-like
Zinc-Finger Transcription Factor 5 (KLF5) is highly expressed in large and giant unruptured
cerebral aneurysms, World Neurosurg, 78: 114-121, 2011124. Harada M, Morita N, Uno M, Satomi J, Izumi Y, Asanuma K, Nishitani H, Kaji R, Nagahiro S,
Incidence and clinical correlation of intracranial hemorrhages observed by 3-tesla gradient echo
T2*-weighted images following intravenous thrombolysis with recombinant tissue plasminogenactivator, Cerebrovascular Diseases, 29: 571-575, 2010125. Inoue N, Nagahiro S, Kaji R, Goto S, Long-term suppression of Meige syndrome after pallidal
stimulation: a 10-year follow-up study, Movement Disorders, 25: 1756-1758, 2010126. Matsuzaki K, Kageji T, Watanabe H, Hirose T, Nagahiro S, Pilomyxoid astrocytoma of thecervical spinal cord successfully treated with chemotherapy - case report -, Neurologia medicochirurgica, 50: 939-942, 2010
127. Mure H, Matsuzaki K, Kitazato KT, Mizobuchi Y, Kuwayama K, Kageji T, Nagahiro S, Akt2 and
Akt3 play a pivotal role in malignant gliomas, Neuro-Oncology, 12: 221-232, 2010
128. Nakagawara J, Minematsu K, Okada Y, Tanahashi N, Nagahiro S, Mori E, Shinohara Y,
Yamaguchi T, Thrombolysis with 0.6 mg/kg intravenous alteplase for acute ischemic stroked inroutine clinical practice (The Japan post-marketing alteplase registration study (J-MARS), Stroke,
41(9): 1984-1989, 2010129. Okazaki T, Nishi T, Yamashiro S, Koga K, Nagahiro S, Fujioka S, De novo formation and ruptureof an intracranial aneurysm 10 months after normal findings on conventional magnetic resonanceangiography in a patient with no history of intracranial lesions - case report -, Neurologia medicochirurgica, 50: 309-312, 2010
130. Sako W, Morigaki R, Nagahiro S, Kaji R, Goto S, Olfactory type G-protein α subunit in striosomematrix Dopamine systems in adult mice, Neuroscience, 170: 497-502, 201014

131. Tada Y, Yagi K, Kitazato KT, Tamura T, Kinouchi T, Shimada K, Matsushita N, Nakajima N,
Satomi J, Kageji T, Nagahiro S, Reduction of endothelial tight junction proteins is related tocerebral aneurysm formation in rats, Journal of Hypertension, 28: 1883-1891, 2010132. Tada Y, Uno M, Matsubara S, Suzue A, Shimada K, Morita N, Harada M, Nagahiro S,
Reversibility of ischemic findings on 3-T T2*-weighted imaging after emergency superficial
temporal artery-middle cerebral artery anastomosis in patients with progressive ischemic stroke two case reports -, Neurologia medico-chirurgica, 50: 1006-1011, 2010
133. Yagi K, Tada T, Kitazato KT, Tamura T, Satomi J, Nagahiro S, Ibudilast inhibits cerebral
aneurysms by down-regulating inflammation -Related molecules in the vascular wall of rats-,
Neurosurgery, 66: 551-559, 2010
134. Kuwayama K, Matsuzaki K, Mizobuchi Y, Mure H, Kitazato KT, Kageji T, Nakao M, Nagahiro
S, Promyelocytic leukemia protein induces apoptosis due to caspase-8 activation via therepression of NFkB activation in glioblastoma, Neuro-Oncology, 11: 132-141, 2009135. Morita N, Harada M, Uno M, Matsubara S, Nagahiro S, Nishitani H, Evaluation of initial
diffusion-weighted image findings in acute stroke patients using a semiquantitative score, Magn
Reson Med Sci, 8: 47-53, 2009136. Mure H, Matsuzaki K, Kitazato KT, Mizobuchi Y, Kuwayama K, Kageji T, Nagahiro S, Akt2 and
Akt3 play a pivotal role in malignant gliomas, Neuro-Oncology, 12(3): 221-232, 2009137. Okazaki T, Kageji T, Matsuzaki K, Horiguchi H, Hirose T, Watanabe H, Ohnishi T, Nagahiro S,
Primary anaplastic pleomorphic xanthoastrocytoma with widespread neuroaxis dissemination atdiagnosis - a pediatric case report and review of the literature, Journal of Neurooncology, 94: 431437, 2009138. Tada Y, Kitazato KT, Tamura T, Yagi K, Shimada K, Kinouchi T, Satomi J, Nagahiro S, Role ofmineralocorticoid receptor on experimental cerebral aneurysms in rats, Hypertension, 56: 552557, 2009139. Tamura T, Jamous MA, Kitazato KT, Yagi K, Tada Y, Uno M, Nagahiro S, Endothelial damage
due to impaired nitric oxide bioavailability triggers cerebral aneurysm formation in female rats,
Journal of Hypertension, 27: 1284-1292, 2009
140. Yagi K, Kitazato KT, Uno M, Tada Y, Kinouchi T, Shimada K, Nagahiro S, Edaravone, a free
radical scavenger, inhibits MMP-9-related brain hemorrhage in rats treated with tissue
15

plasminogen activator, Stroke, 40: 626-631, 2009141. Yamasaki H, Matsubara S, Sasaki I, Nagahiro S, Retinal artery embolization during carotid
angioplasty and carotid artery stenting -case report-, Neurologia medico-chirurgica, 49: 213-216,
2009
142. Liu H, Kitazato KT, Uno M, Yagi K, Kanematsu Y, Tamura T, Tada Y, Kinouchi T, Nagahiro S,
Protective mechanisms of the angiotensin II type 1 receptor blocker candesartan against cerebral
ischemia: in-vivo and in-vitro studies, Journal of Hypertension, 26(7): 1435-1445, 2008
143. Morigaki R, Uno M, Matsubara S, Satoh K, Nagahiro S, Choreoathetosis due to rupture of a distal
accessory anterior cerebral artery aneurysm, Cerebrovascular Diseases, 25: 285-287, 2008
144. Mizobuchi Y, Matsuzaki K, Kuwayama K, Kitazato K, Mure H, Kageji T, Nagahiro S, REIC/Dkk3 induces cell death in human malignant glioma, Neuro-Oncology, 10: 244-253, 2008
145. Morita N, Harada M, Uno M, Matsubara S, Matsuda T, Nagahiro S, Nishitani H, Ischemic findingsof T2*-weighted 3-Tesla MRI in acute stroke patients, Cerebrovascular Diseases, 26: 367-375,
2008
146. Oto J, Suzue A, Inui D, Fukuta Y, Hosotsubo K, Torii M, Nagahiro S, Nishimura M, Plasma
proinflammatory and anti-inflammatory cytokine and catecholamine concentrations as predictorsof neurological outcome in acute stroke patients, Journal of Anesthesia, 22: 207-212, 2008
147. Goto S, Shimazu H, Matsuzaki K, Tamura T, Murase N, Nagahiro S, Kaji R, Thalamic Vocomplex vs pallidal deep brain stimulation for focal hand dystonia, Neurology, 70: 1500-1501,
2008
148. Manabe S, Satoh K, Matsubara S, Satomi J, Hanaoka M, Nagahiro S, Characteristics, diagnosis
and treatment of hypoglossal canal dural areteriovenous fistula: report of nine cases,
Neuroradiology, 50: 715-721, 2008
149. Uno M, Suzue A, Nishi K, Nagahiro S, Hemodynamic cerebral ischemia during carotid
endarterectomy evaluated by intraoperative monitoring and post-operative diffusion-weighted
imaging, Neurol Res, 29：70-77, 2007
150. Tamura A, Ichihara T, Takata S, Minagawa T, Kuwamura Y, Bando T, Yasui N, Nagahiro S, Studyon factors related to loss of lower extremity muscle mass in elderly acute stroke patients, The
Journal of Nursing Investigation, 6: 23-27, 200716

151. Jamous MA, Nagahiro S, Kitazato KT, Tamura T, Aziz HA, Shono M, Satoh K, Endothelial injury
and inflammatory response induced by hemodynamic changes preceding intracranial aneurysm
formation: experimental study in rats, J.Neurosurg., 107: 405-411, 2007
152. Suzue A, Uno M, Kitazato KT, Nishi K, Yagi K, Liu H, Tamura T, Nagahiro S, Comparison
between early and late carotid endarterectomy for symptomatic carotid stenosis inn relation tooxidized low-density lipoprotein and plaque vulnerability, Journal of Vascular Surgery, 46(5):870-875, 2007
153. Kageji T, Nagahiro S, Matsuzaki K, Kanematsu Y, Nakatani M, Y.Okamoto, Watanabe T,
Successful neoadjuvant synchronous chemo- and radiotherapy for disseminated primary
intracranial chriocarcinoma: case report, Neurooncol, 83:199-204, 2007
154. Hanaoka M, Satoh K, Satomi J, Matsubara S, Nagahiro S, Takimoto O, Ohbayashi M,
Microcatheter pull-up technique in the transvenous embolization of an isolated sinus duralarteriovenous fistula, J. Neurosurg, 104：974-977, 2006
155. Kageji T, Nagahiro S, Matsuzaki K, Mizobuchi Y, Toi H, Nakagawa Y, Kumada H, Boron newtron
capture therapy using mixed epithermal and thermal neutron beams in patients with malignant
glioma －Correlation between radiation dose and radiation injury and clinical outcome－, Int. J.
Radiation Concology Biol. Phys, 65：1446-1455, 2006
156. Yamada K, Goto S, Matsuzaki K, Tamura T, Murase N, Shimazu H, Nagahiro S, Kuratsu J, R Kaji,
Alleviation of camptocormia by bilateral subthalamic nucleus stimulation in a patient with
Parkinson's disease, Parkinsonism and Related Disorders, 12：372-375, 2006
157. Tamura A, Ichihara T, Takata S, Minagawa T, Kuwamura Y, Bando T, Kondo H, Yasui N, Nagahiro
S, Changes in lower extremity muscle mass among bedridden patients with post-stroke.
hemiplegia in the acute post-stroke period, The Journal of Nursing Investigation, 5：18-21, 2006
158. Morigaki R, Uno M, Suzue A, Nagahiro S, Hemichorea due to hemodynamic ischemia associatedwith extracranial carotid artery stenosis, J.Neurosurg, 105：142-147, 2006
159. Goto S, Yamada K, Shimazu H, Murase N, Matsuzaki K, Tamura T, Nagahiro S, Kuratsu J, KajiR, Impact of bilateral pallidal stimulation on DYT1-generalized dystonia in Japanese patients,
Movement Disorders, 21：1785-1787, 2006
160. Uno M, Kitazato KT, Suzue A, Matsuzaki K, Harada M, Itabe H, Nagahiro S, Inhibition of brain
damage by edaravone, a free radical scavenger, can be monitored by plasma biomarkers that detect17

oxidative and astrocyte damage in patients with acute cerebral infarction, Free Radical Biology& Medicine, 39: 1109-1116, 2005
161. Uno M, Harada M, Takimoto O, Kitazato KT, Suzue A, Yoneda K, Morita N, Itabe H, Nagahiro
S, Elevation of plasma oxidized LDL in acute stroke patients is associated with ischemic lesions
depicted by DWI and predictive of infarct enlargement, Neurological Research, 27: 94-102, 2005
162. Yagi K, Kageji T, Nagahiro S, Murayama Y, Multiple cystic cavernous angiomas associated withhemorrhage, Acta Neurochir, 147: 201-203, 2005
163. Jamous MA, Nagahiro S, Kitazato KT, Satoh K, Satomi J, Vascular corrosion casts mirroring earlymorphological changes that lead to the formation of saccular cerebral aneurysm: an experimental
study in rats, J. Neurosurg., 102: 532-535, 2005
164. Satomi J, Satoh K, Matsubara S, Nakajima N, Nagahiro S, Angiographic changes in venous
drainage of cavernous sinus dural arteriovenous fistulae after palliative transarterial embolization
or observational management: A proposed stage classification, Neurosurgery, 56: 494-502, 2005
165. Uno M, Kitazato KT, Suzue A, Itabe H, Liu H, Nagahiro S, Contribution of an imbalance
betweenn oxidant-antioxidant systms to plaque vulnerability in patients with carotid arterystenosis, J.Neurosurg., 103: 518-525, 2005
166. Jamous MA, Nagahiro S, Kitazato KT, Satomi J, Satoh K, Role of estrogen deficiency in theformation and progression of cerebral aneurysms. Part I: experimental study of the effect ofoophorectomy in rats, J.Neurosurg, 103：1046-1051, 2005
167. Jamous MA, Nagahiro S., Kitazato KT, Tamura T, Kuwayama K, Satoh K, Role of estrogen
deficiency in the formation and progression of cerebral aneurysms.

Part II: experimental studyof the effect of hormone replacement therapy in rats, J.Neurosurg, 103：1052-1057, 2005
168. Yagi K, Satoh K, Satomi J, Matsubara S, Nagahiro S, Evaluation of aneurysm stability after
endovascular embolization with guglielmi detachable coils: Correlation between long-term
stability and volume embolization ratio, Neurologia medico-chirurgica, 45：561-566, 2005
169. Matsuzaki M, Uno M, Kageji T, Hirose T, Nagahiro S, Anaplastic ganglioglioma of
cerebellopontine angle: A case report and review of literatures, Neurol Med Chir (Tokyo), 45:
591-595, 2005
170. Okazaki T, Satomi J, Satoh K, Hirasawa M, Nagahiro S, Rescue revascularization therapy with a18

stent-in-stent technique for acute intracranial internal carotid artery occlusion - case report -,Neurologia medico-chirurgica, 45(5): 253-258, 2005
171. Nagahiro S, Kageji T, Clinoidal meningioma encasing the internal carotid artery, Neurosurgery ofComplex Vascular Lesions and Tumors, ed. by S.Kobayashi, Thieme Medical Publishers New
York, 2005, pp211-214
172. Jamous MA, Satoh K, Satomi J, Matsubara S, Nakajima N, Uno M, Nagahiro S, Detection ofenlarged cortical vein by magnetic resonance imaging contributes to early diagnosis and better
outcome for patients with anterior cranial fossa dural arteriovenous fistula, Neurol Med Chir,
44(10), 516-520, 2004
173. Horiguchi H, Sano T, Qian ZR, Hirokawa M, Kagawa N, Yamaguchi T, Hirose T, Nagahiro S,
Expression of cell adhesion molecules in chordomas: an immunohistochemical study of 16 cases,
Acta Neuropathol, 107, 91-96, 2004
174. Jamous MA, Satoh K, Matsubara S, Satomi J, Nakajima N, Uno M, Nagahiro S, Ischemic basilar
artery dissecting aneurysm treated by stenting only--case report, Neurol Med Chir, 44(2), 77-81,
2004
175. Kageji T, Nagahiro S, Mizobuchi Y, Toi H, Nakagawa Y, Kumada H, Radiation injury of boron
neutron capture therapy using mixed epithermal- and thermal neutron beams in patients withmalignant glioma
176. Kageji T

Appl Radiat Isot, 61(5), 1063-1067, 2004

Nagahiro S, Uyama S, Mizobuchi Y, Toi H, Nakamura M, Nakagawa Y,

Histopathological findings in autopsied glioblastoma patients treated by mixed neutron beam
BNCT, Journal of Neuro-Oncology, 68, 25-32, 2004
177. Kanematsu M, Satoh K, Nakajima N, Hamazaki F, Nagahiro S, Ruptured aneurysm arising froma basilar artery fenestration and associated with a persistent primitive hypoglossal artery. Case
report and review of the literature J Neurosurg, 101(3), 532-535, 2004
178. Liu H, Uno M, Kitazato KT, Suzue A, Manabe S, Yamasaki H, Shono M, Nagahiro S, Peripheral
oxidative biomarkers constitute a valuable indicator of the severity of oxidative brain damage inacute cerebral infarction, Brain Research, 1025, 43-50, 2004
179. Manabe S, Nishimura N, Yamamoto Y, Kitamura H, Morimoto S, Imai M, Nagahiro S, Seino S,
Sasaki T, Identification and characterization of Noc2 as a potential Rab3B effector protein inepithelial cells, Biochem Biophys Res Commun, 316, 218-225, 2004
180. Nakajima N, Nagahiro S, Matsubara S, Satoh K, Ruptured de novo thrombotic giant aneurysm
induced by ethyl 2-cyanoacrylate: case report, Sugical Neurology, 62, 346-352, 2004

19

181. Nomura M, Kannuki S, Kuwayama K, Kohyama Y, Hayashi Y, Yamamoto E, Kaji T, Uehara K,
Nishikado A, Ito S, Nakaya Y, Nagahiro S, A patient with Wallenberg's syndrome induced bysevere cough, J. Clinical Neuroscience, 11, 179-182, 2004
182. Uno M, Satoh K, Matsubara S, Satomi J, Nakajima N, Nagahiro S, Does multimodality therapyof arteriovenous malformations improve patient outcome?, Neurol Res, 26(1), 50-54, 2004
183. Yagi K, Kageji T, Nagahiro S, Horiguchi H, Growing teratoma syndrome in a patient with a nongerminomatous germ cell tumor in the neurohypophysis--case report, Neurol Med Chir , 44(1),33-37, 2004
184. Yagi K, Satoh K. Satomi J, Nagahiro S, Primitive vertebrovasilar system associated with aruptured aneurysm, AJNR, 25, 781-783, 2004
185. Kageji T, Nagahiro S, Horiguchi H, Watanabe T, Szuya H, Okamoto Y, Kuroda Y, Successful
high-dose chemotherapy for widespread neuroaxis dissemination of an optico-hypothalamic
juvenile pilocytic astrocytoma in an infant: a case report, Journal of Neuro-Oncology, 62, 281287, 2003
186. Matsuzaki K, Minami T, Tojo M, Honda Y, Saitoh N, Nagahiro S, Saya H, Nakao M, PMLnuclear bodies are involved in cellular serum response, Genes to Cells, 8, 275-286, 2003
187. Matsuzaki K, Minami T, Tojo M, Honda Y, Uchimura Y, Saitoh H, Yasuda H, Nagahiro S, Saya
H, Nakao M, Serum response factor is modulated by the SUMO-1 conjugation system,
Biochemical and Biophysical Research Communications, 306, 32-38, 2003
188. Ogawa K, Nagahiro S, Arakaki R, Ishimaru N, Kobayashi M, Hayashi Y, Anti-α-Fodrin
autoantibodies in moyamoya disease, Stroke, 34, e244-e246, 2003
189. Shinno K, Nagahiro S, Uno M, Kannuki S, Nakaiso M, Sano N, Horiguchi H, Neurocutaneous
melanosis associated with malignant leptomeningeal melanoma in an adult: clinical significanceof 5-S-cysteinyldopa in the cerebrospinal fluid---case report, Neurol Med Chir, 43(12), 619-625,
2003
190. Toi H, Uno M, Harada M, Yoneda K, Morita N, Matsubara S, Satoh K, Nagahiro S, Diagnosisof acute brain-stem infarcts using diffusion-weighed MRI, Neuroradiology, 45, 352-356, 2003
191. Uno M, Kitazato KT, Nishi K, Itabe H, Nagahiro S, Raised plasma oxidised LDL in acutecerebral infarction, J Neurol Neurosurg Psychiat, 74, 312-316, 2003
192. Yamasaki H, Mizusawa N, Nagahiro S, Yamada S, Sano T, Itakkura M, Yoshimoto K, GHsecreting pituitary adenomas infrelquently contain inactivating mutations of PRKA1A and LOHof 17q23-24, Clinical Endocrinology, 58, 464-470, 2003
193. Kageji T, Nagahiro S, Otersen B, Gabel D, Nakaichi M, Nakagawa Y, Subcellular biodistribution20

of sodium borocaptate (BSH: Na2B12H11SH) in a rat glioma model in boron neutron capture
therapy, Journal of Neuro-Oncology, 59(2), 135-142, 2002
194. Nishi K, Uno M, Fukuzawa K, Horiguchi H, Shinno K, Nagahiro S, Clinicopathologicalsignificance of lipid peroxidation in carotid plaques, Atherosclerosis, 160(2), 289-296, 2002
195. Kageji T, Nagahiro S, Uyama S. Mizobuchi Y, Nakagawa Y

Clinical review of BNCT

using mixed neutron beam in patients with malignant glioma, Research and Development in
Neutron Capture Therapy, Monduzzi Editore, Medimond Inc., 2002, pp1085-1091
196. Kaji Y, Nakayama H, Akutagawa M, Shichijo F, Zhang Q, Nagashino H, Kinouchi Y, Nagahiro
S, Integrated EEG monitoring system of brain functions during operations, Recent Advances in
Human Brain Mapping, ed. by K.Hirata et al., ELSEVIER, 2002, pp289-296,
197. Kitade S, Zhang Q, Shichijo F, Nagahiro S, Kinouchi Y, Morita Y, ERP and topography in a caseof semantic amnesia with severe impairment in face cognition, Recent Advances in Human Brain
Mapping, ed. by K.Hirata et al., ELSEVIER, 2002, pp777-782
198. Uno M, Harada M, Yoneda K, Matsubara S, Satoh K, Nagahiro S, Can diffusion- and perfusionweighted magnetic resonance imaging evaluate the efficacy of acute thrombolysis in patientswith internal carotid artery or middle cerebral artery occlusion?, Neurosurgery, 50, 28-35, 2002
199. Nakaiso M, Uno M, Harada M, Kageji T, Takimoto O, Nagahiro S, Brain abscess andglioblastoma identified by combined proton magnetic resonance spectroscopy and diffusionweighted magnetic resonance imaging--two case reports, Neurol Med Chir, 42(8), 346-348, 2002
200. Nishi K, Itabe H, Uno M, Kitazato KT, Horiguchi H, Shinno K, Nagahiro S, Oxidized LDL incarotid plaques and plasma associates with plaque instability, Arteriosclearosis, Thrombosis, and
Vascular Biology, 22, 1649-1654, 2002
201. Shichijo F, Kaji Y, Akutagawa M, Takimoto O, Nagahiro S, Nakayama H, Zhang Q, Kinouchi Y,
The new Windows-based deviation ratio topography system, Recent Advances in Human Brain
Mappinged, by K.Hirata et al., ELSEVIER, 2002, pp377-382

202. Uno M, Nishi K, Shinno K, Nagahiro S, Carotid endarterectomy with external shunt: a new
device and indication for use: technical note, Neurosurgery, 48(5), 1174-1177, 2001
203. Uno M, Hamazaki F, Kohno T, Sebe A, Horiguchi H, Nagahiro S, Combined therapeutic
approach of intra-arterial thrombolysis and carotid endarterectomy in selected patients with acutethrombotic carotid occlusion, J Vasc Surg, 34(3), 532-540, 2001
204. Bando K, Satoh K, Matsubara S, Nakatani M, Nagahiro S, Hyperperfusion phenomenon after
percutaneous transluminal angioplasty for atherosclerotic stenosis of the intracranial vertebral
artery, J Neurosurg, 94, 826-830, 2001
21

205. Horiguchi H, Sano T, Toi H, Kageji T, Hirokawa M, Nagahiro S, Endolymphatic sac tumor
associated with a von Hippel-Lindau disease patient: an immunohistochemical study, Mod
Pathol, 14, 727-732, 2001
206. Jamous MA, Satoh K, Kageji T, Satomi J, Matsubara S, Nagahiro S, Hayashi M, Nakagawa S
Anterior ischemic optic neuropathy after combined ophthalmic artery embolization andcraniofacial surgery ─case report─, Neurol Med Chir, 41, 419-422, 2001
207. Kageji T, Nagahiro S, Kitamura K, Nakagawa Y, Hatanaka H, Haritz D, Grochulla F,
Haselsberger K, Gabel D, Optimal timing of neutron irradiation for boron neutron capture
therapy after intravenous infusion of sodium borocaptate in patients with glioblastoma,
International Journal of Radiation, Oncology, Biology and Physics, 51, 120-130, 2001
208. Kageji T, Nagahiro S, Matsumoto K, Otersen B, Gabel D, Nakaichi M, Nakagawa Y, Subcellularbiodistribution of Na2B12H11SH (BSH) in rat glioma model, Frontiers in Neutron Capture
Therapy, ed.by Hawthorne et al., Kluwer Academic, Plenum Publishers, New York, 2001,
pp927-931
209. Kageji T, Nagahiro S, Matsumoto K, Otersen B, Gabel D, Nakagawa Y, Membrane binding of
Na2B12H11SH (BSH) with phosphatidylcholine in boron neutron capture therapy
Frontiers in Neutron Capture Therapy, ed.by Hawthorne et al., Kluwer Academic, Plenum
Publishers, New York, 2001, pp1039-1044
210. Matsubara S, Satoh K, Satomi J, Miyamoto T, Uno M, Nagahiro S, Guglielmi detachable coilembolization for ruptured lower-midbasilar trunk aneurysms - a report of five cases -,Neuroradiology, 43, 884-890, 2001
211. Murayama Y, Sakurama K, Satoh K, Nagahiro S, Identification of the carotid artery dural ringby using three-dimensional computerized tomography angiography. Technical note, J Neurosurg,
95(3), 533-536, 2001
212. Satoh K, Satomi J, Nakajima N, Matsubara S, Nagahiro S, Cerebellar hemorrhage caused bydural arteriovenous fistula: a review of five cases, Journal of Neurosurgery, 94, 422-426, 2001
213. Uno M, Harada M, Nagahiro S, Quantitative evaluation of cerebral metabolites and cerebral
blood flow in patients with carotid stenosis, Neurol Res, 23(6), 573-580, 2001
214. Uno M, Harada M, Okada T, Nagahiro S, Diffusion-weighted and perfusion-weighted magnetic
resonance imaging to monitor acute intra-arterial thrombolysis, J Stroke Cerebrovasc Dis, 9(3),113-120, 2000
215. Horiguchi H, Hirose T, Sano T, Nagahiro S, Seki K, Fujimoto N, Kaneko F, Kusaka K,
Meningioma with granulofilamentous inclusions, Ultrastructural Pathology, 24, 267-271, 2000

22

216. Kawano Y, Miyazaki T, Watanabe T, Suzue A, Kannuki S, Kageji T, Onishi T, Kaneko M,
Kanamaru S, Wakata Y, Nakagawa R, Suenaga K, Suzuya H, Abe T, Nagahiro S, Kuroda Y,
Takaue Y, HLA-mismatched CD34-selected stem cell transplant complicated by HHV-6
reactivation in the central nervous system, Bone Marrow Transplantation, 25, 787-790, 2000
217. Nakajima N, Nagahiro S, Sano T, Satomi J, Satoh K, Phenotypic modulation of smooth muscle
cells in human cerebral aneurysmal walls, Acta Neuropathol, 100, 475-480, 2000
218. Horiguchi H, Hirose T, Sano T, Nagahiro S, Loss of chromosome 10 in glioblastoma: relation to
proliferation and angiogenesis, Pathol Int, 49(8), 681-686, 1999
219. Morioka M, Fukunaga K, Hasegawa S, Okamura A, Korematsu K, Kai Y, Hamada, J Nagahiro
S, Miyamoto E, Ushio Y, Activities of calcineurin and phosphatase 2A in the hippocampus after
transient forebrain ischemia, Brain Research, 828, 135-144, 1999
220. Satoh K, Satomi J, Nakajima N, Nagahiro S, Endovascular treatment using detachable coils for
non-ruptured intracranial aneurysm, Interventional Neuroradiology, 5 (Suppl 1), 67-70, 1999
221. Uno M, Ueda S, Shinno K, Nishi K, Nishitani K, Nagahiro S, Coronary artery stenosis evaluatedby combined carotid and coronary angiography in patients undergoing carotid endarterectomy,
Neurol Med Chir , 39(8), 567-574, 1999
222. Horiguchi H, Hirose T, Kannuki S, Nagahiro S, Sano T, Gliosarcoma: an immunohistochemical,
ultrastructural and fluorescence in situ hybridization study, Pathol Int, 48(8), 595-602, 1998
223. Nagahiro S, Uno M, Satoh K, Pathophysiology and treatment of cerebral ischemia,
Microcirculation annual, 14: 33-34, 1998
224. Nagahiro S, Uno M, Satoh K, Goto S, Morioka M, Ushio Y, Pathophysiology and treatment of
cerebral ischemia, The Journal of Medical Investigation, 45: 57-70, 1998
225. Satoh K, Satomi J, Matsubara S, Nagahiro S, Measurement of volume ratio to predict coilcompaction, on aneurysmal embolization, Interventional Neuroradiology,

30; 4(Suppl 1):

179-182, 1998
226. Shichijo F, Soga T, Nagahiro S, Functional dynamic EEG monitoring with deviation ratio
topography (DRT)

Brain Topography Today, ed. by Y.Koga et al., Elsevier Science B.V., 1998,

pp636-641
227. Shinno K, Ueda S, Uno M, Nishitani K, Nagahiro S, Harada M, Hyperperfusion syndrome
following carotid endarterectomy: evaluation using diffusion-weighted magnetic resonanceimaging--case report, Neurol Med Chir, 38(9), 557-561, 1998
228. Uno M, Nakajima N, NishK, Shinno K, Nagahiro S, Hyperperfusion syndrome after
extracranial-intracranial bypass in a patient with moyamoya disease
23

─case report─, Neurol

Med Chir, 38(7): 420-424, 1998
229. Inoue N, Yamamoto YL, Korematsu K, Goto S, Nagahiro S, Oyama T, Yamada K, Ushio Y,
Effectiveness of retrograde perfusion of the cerebral vein for attenuating neuronal injury after
transient ischemia following reperfusion in the rat brain, Neurol Med Chir (Tokyo), 37(3), 243249, 1997
230. Mimata C, Kitaoka M, Nagahiro S, Iyama K, Hori H, Yoshioka H, Ushio Y, Differential
distribution and expressions of collagens in the cerebral aneurysmal wall, Acta Neuropathol,
94:197-206, 1997
231. Hondo H, Shichijo F, Nagahiro S, Izumidani T, Nishitani K, Matsumoto K, CT-controlledstereotactic aspiration surgery for hypertensive putaminal hemorrhage: Hematoma volume andsurgical outcome, Brain Hemorrhage '97
232. Nishi K,, 55-60, 1997

Uno M, Ueda S, Nishitani K, Shinno K, Nagahiro S, Horiguchi H, Sano T, Carotid

endoarterectomy for radiation-induced carotid artery stenosis ─Case report─, Neurologia
medico-chirurgica, 37(11):, 844-848, 1997
233. Morioka M, Nagahiro S, Fukunaga K, Miyamoto E, Ushio Y, Calcineurin in the adult rat
hippocampus: Different distribution in CAI and CA3 subfields, Neuroscience, 78(3):673-684,
1997
234. Nagahiro S, J. Hamada, Y. Sakamoto, Y. Ushio, Follow-up evaluation of dissecting aneurysmsof the vertebrovasilar circulation by using gadolinium-enhanced magnetic resonance imaging, J
Neurosurg, 87, 385-390, 1997
235. Satoh K, Matsubara S, Hondoh H, Nagahiro S, Intracranial Aneurysm Embolization Using
Interlocking Detachable Coils. Correlation between Volume Embolization Rate and CoilCompaction, Interv Neuroradiol, 30; 3 (Suppl 2), 125-128, 1997
236. Hamada J, Kai Y, Nagahiro S, Hashimoto N, Iwata H, Ushio Y, Embolization with cellulose
porous beads, II: Clinical trial, AJNR Am J Neuroradiol, 17(10), 1901-1906, 1996
237. Hamada J, Nagahiro S, Mimata C, Kaku T, Ushio Y, Reconstruction of the posterior inferior
cerebellar artery in the treatment of giant aneurysms. Report of two cases, J Neurosurg, 85(3),496-499, 1996
238. Hamada J, Kai Y, Nagahiro S, Hashimoto N, Ushio Y , A new particulate embolic agent:clinical
trial, Advances in Interventional Neuroradiology and Intravascular Neurosurgery, 11-14, 1996
239. Inoue N, Goto S, Korematsu K, Oyama T, Yamada K, Nagahiro S, Ushio Y, Cytochrome oxidase
activity during acute focal ischaemia in rat brain. A pathophysiology of acute focal ischaemia:
Part 2, Acta Neurochir , 138(9), 1126-1131, 199624

240. Inoue N, Yamamoto YL, Nagao T, Goto S, Nagahiro S, Ushio Y, Alterations of local cerebral
blood flow, phorbol 12,13-dibutyrate binding activity, and histological damage during acutefocal ischaemia in rat brain. A pathophysiology of acute focal ischaemia: Part 1, Acta Neurochir,
138(9), 1118-1124, 1996
241. Kai Y, Hamada J, Nagahiro S, Ushio Y, Cellulose beads for a particulate embolic agent-an
experimental study, Advances in Interventional Neuroradiology and Intravascular Neurosurgery,
7-10, 1996
242. Yamada K, Goto S, Sato K, Yoshikawa M, Okamura A, Nagahiro S, Ushio Y, 'REACTIVE
CHANGE'OF THE SUBSTANTIA NIGRA NEURONS SUBSEQUENT TO STRIATAL
INFARCTION IN RATS, Biomedical Research, 17(5), 339-346, 1996
243. Korematsu K, Goto S, Nagahiro S, Yamada K, Yoshikawa M, Okamura A, Ushio A, Timesequential change in apomorphine-induced rotational behavior following transient middle
cerebral artery occlusion in rats, Biomedical Research, 17(5), 395-398, 1996
244. Nagahiro S, Mantani A, Yamada K, Ushio Y, Multiple cerebral arterial occlusion in a young
patient with Sj gren syndrome: case report, Neurosurgery, 38, 592-595, 1996
245. Hirai T, Korogi Y, Sakamoto Y, Takahashi M, Nagahiro S, Ushio Y, Three-dimensional Time-ofFlight Magnetic Resonance Angiography in the Evaluation of Moyamoya Disease, International
Journal of Neuroradiology, 2(1), 20-24, 1996
246. Diksic M, Nagahiro S, Grdisa M, The regional rate of serotonin synthesis estimated by the amethyl-tryptophan method in rat brain from a single time point, J Cereb Blood Flow Metab, 15,806-813, 1995
247. Du C, Korogi Y, Nagahiro S, Sakamoto Y, Takeda A, Ushio Y, Hirai T, Higashida Y, Takahashi
M, Hemifacial spasm: three-dimensional MR images in the evaluation of neurovascularcompression, Radiology, 197, 227-231, 1995
248. Hirai T, Korogi Y, Sakamoto Y, Hamatake S, Murakami R, Ikushima I, Takahashi M Nagahiro
S, Ushio Y, MR angiography of the persistent trigeminal artery variant, J Computer Assisted
Tomography, 19, 495-497, 1995
249. Korematsu K, Goto S, Nagahiro S, Inoue N, Oyama T, Yamada K, Ushio Y, Changes ofphosphotyrosine immunoreativity on microglia in the rat substantia nigra following striatal
ischemic injury, Glia, 13, 147-153, 1995
250. Korogi Y, Nagahiro S, Du C, Sakamoto Y, Takada A, Ushio Y, Ikushima I, Takahashi M,
Evaluation of vascular compression in trigeminal neuralgia by 3D time-of-flight MRA, J Comput
Assist Tomogr, 19(6), 879-884, 1995

25

251. Morioka M, Fukunaga K, Nagahiro S, Kurino M, Ushio Y, Miyamoto E, Glutamate-induced lossof Ca2+//calmodulin-dependent protein kinase II activity in cultured rat hippocampal neurons, J
Neurochem, 64, 2132-2139, 1995
252. Nagahiro S, Ushio Y, Sumi M, Takahashi M, Godolinium-DTPA-enhanced MRI in transientcerebral ischemia: experimental study, Proceedings of the XV symposium Neuroradiologicum,
Takahashi M, Korogi Y, Moseley I, Springer, 1995
253. Sugimoto S, Yamamoto YL, Nagahiro S, Diksic M, Permeability changes and brain tissue
damage after intracarotid administration of cisplatin studied by double-tracer autoradiography
in rats, J Neuro-Oncol, 24, 229-240, 1995
254. Tsuiki K, Takada A, Nagahiro S, Grdisa M, Diksic M, Pappius HM, Synthesis of serotonin intraumatized rat brain, J Neurochem, 64, 1319-1325, 1995
255. Yamada K, Goto S, Oyama T, Yoshikawa M, Nagahiro S, Ushio Y, Striatal cells containing theCa2+binding protein calretinin (protein-10) in ischemia-induced neuronal injury, Acta
Neuropathol, 89, 172-177, 1995
256. Goto S, Nagahiro S, Korematsu K, Kogo K, Ushio Y, Subdivisional ischemic injury of thestriatum causes apomorphine-induced rotational behavior in rats, Acta Neuropathol, 87, 211-216,
1994
257. Goto S, Yamada K, Inoue N, Nagahiro S, Ushio Y, Increased expression of growth-associatedprotein GAP-43/B-50 following cerebral hemitransection and striatal ischemic injury in thesubstantia nigra of adult rats, Brain Res, 647, 333-339, 1994
258. Goto S, Yamada K, Oyama T, Korematsu K, Nagahiro S, Ushio Y, Fukunaga K, Miyamoto E,
Hoffer W, Cellular localization of type II Ca2+/calmodulin-dependent protein kinase in the rat
basal ganglia and intrastriatal lgrafts derived from fetal striatal primordia, in comparison withthat of Ca2+/calmodulin-regulated protein phosphatase, calcineurin, Neuroscience, 62, 698-705,
1994
259. Korematsu K, Goto S, Nagahiro S, Ushio Y, Microglial response to transient focal cerebral
ischemia: an immunocytochemical study on the rat cerebral cortex using anti-phosphotyrosine
antibody, J Cereb Blood Flow Metab, 14, 825-830, 1994
260. Nagahiro S, Goto S, Korematsu K, Sumi M, Takahashi M, Ushio Y, Diseruption of the bloodcerebrospinal fluid barrier by transient cerebral ischemia, Brain Res, 633, 305-311, 1994
261. Nagahiro S, Goto S, Kogo K, Sumi M, Takahashi M, Ushio Y, Sequential changes in ischemic
edema following transient focal cerebral ischemia in rats: magnetic resonance imaging study,
Neurol Med Chir (Tokyo), 34, 412-417, 1994

26

262. Nagahiro S, Kochi M, Seto H, Uemura S, Ushio Y, Surgical results of malignant skull basetumors with intracranial extension, Skull Base Surgery, Sumi M, Karger (Basel), 1994,

pp152-155
263. Yamada K, Goto S, Inoue N, Nagahiro S, Ushio Y, Elevated immunoreactivity for glutamic aciddecarboxylase in the rat cerebral cortex following transient middle cerebral artery occlusion,
Acta Neuropathol, 88, 55-59, 1994
264. Yamada K, Goto S, Oyama T, Inoue N, Nagahiro S, Ushio Y, In vivo induction of the growth
associated protein GAP43/B-50 in rat astrocytes following transient middle cerebral artery
occlusion, Acta Neuropathol, 88, 553-557, 1994
265. Yamashiro S, Nagahiro S, Mimata C, Kuratsu J, Ushio Y, Malignant trigeminal shwannoma
associated with xeroderma pigmentosum -case report-, Neurol Med Chir (Tokyo), 34, 817-820,
1994
266. Goto S, Nagahiro S, Korematsu K, Ushio Y, Fukunaga K, Miyamoto E, Hofer W, Cellular
colocalization of calsium/calmodulin-dependent protein kinase II and calcineurin in the rat
cerebral cortex and hippocampus, Neurosci Let, 149, 189-192, 1993
267. Goto S, Nagahiro S, Ushio Y, Kitaoka M, Nishi S, Fukui M, Immunocytochemical detection of
calcineurin and microtubule-associated protein 2 in central neurocytoma, J Neuro-oncol, 16, 1924, 1993
268. Goto S, Nagahiro S, Korematsu K, Ushio Y, Striatonigral involvement following transicent focal
cerebral ishcemia in the rats: an immunohistochemical study on a reversible ischemia model,
Acta Neuropathol, 85, 515-520, 1993
269. Goto S, Korematsu K, Nagahiro S, Ushio Y, Distinct neuronal subset reveals perikaryal
immunostaining for synaptophysin (protein p38) inn the striatum of rats, Acta Neuropathol, 86,
302-305, 1993
270. Goto S, Korematsu K, Inoue N, Yamada K, Oyama T, Nagahiro S, Ushio Y, N-methyl-D-asparate
receptor antagonist MK-801 induced circling behabvior in rats with unilateral striatal ischemic
lesions of nigral 6-hydroxydopamine lesions, Acta Neuropathol, 86, 480-483, 1993
271. Goto S, Korematsu K, Oyama T, Yamada K, Hamada J, Inoue N, Nagahiro S, Ushio Y, Neuronal
induction of 72-kDa heat shock protein following methamphetamine-induced hyperthermia inthe mouse hippocampus, Brain Res, 626, 351-356, 1993
272. Korematsu K, Goto S, Nagahiro S, Ushio Y, Changes of immunoreactivity for synaptophysin("Protein p38") following a transient cerebral ischemia in the rat striatum, Brain Res, 616, 320324, 199327

273. Nagahiro S, Goto S, Yoshioka S, Ushio Y, Dissecting aneurysm of the posterior inferior
cerebellar artery: case report, Neurosurgery, 33, 739-742, 1993
274. Sumi M, Takahashi M, Nagahiro S, Korogi Y, Sakamoto Y, Nishimura R, Morishita S, Hamatake
S, Ushio Y, Correlation of sequential magnetic resonance imaging of experimental brainischemia with histologic changes in gerbils, Investigative Radiology, 28, 994-1003, 1993
275. Goto S, Nagahiro S, Ushio Y, Hofer W, A simple enhancement method for the silver-goldintensified diaminobenzidine reaction in the light microscopic immunoperoxidase technique, J
Histochem Cytochem, 40, 1423-1425, 1992
276. Goto S, Nagahiro S, Ushio Y, Hirano A, Calcineurin, a calcium/calmodulin-regulated protein
phosphatase, in mammalian neuroendocrine cells and neoplasms, Neurosci Let, 143, 51-54, 1992
277. Hamada J, Sato K, Nagahiro S, Ushio Y, Dynamic magnetic resonance appearance of thevertebral dissecting aneurysms, case report, Neurol Med Chir (Tokyo), 32, 698-700, 1992
278. Morioka M, Fukunaga K, Yasugawa S, Nagahiro S, Ushio Y, Miyamoto E, Regional andtemporal alterations in Ca2+/calmodulin-dependent protein kinase II and calcineurin in the
hippocampus of rat brain after transient forbrain ischemia, J Neurochem, 58, 1798-1809, 1992
279. Nagahiro S, Ushio Y, Pathophysiology of hemifacial spasm: electophysiological study,
Kumamoto Med J, 43, 41-52, 1992
280. Nagahiro S, Takada A, Ushio Y, Surgical treatment of hemifacial spasm: results of microvasculardecompression, Kumamoto Med J, 43, 53-62, 1992
281. Diksic M, Nagahiro S, Chaly T, Sourkes TL, Yamamoto YL, Feindel W, Serotonin synthesis ratemeasured in living dog brain by positron emission tomography, J Neurochem, 56, 153-162, 1991
282. Itoyama Y, Seto H, Nagahiro S, Kuratsu J, Uemura S, Ushio Y, Intracranial cystic
hemangiopericytoma, case report, Neurol Med Chir (Tokyo), 31, 210-213, 1991
283. Nagahiro S, Takada A, Matsukado Y, Ushio Y, Microvascular decompression for hemifacial
spasm; patterns of vascular compression in unsuccessfully operated patients, J Neurosurg, 75,
388-392, 1991
284. Nagahiro S, Yamamoto YL, Diksic M, Mitsuka S, Sugimoto S, Feindel W, Neurotoxicity ater
intracarotid 1,3-bis(2-chloroethyl)-1--nitroso-urea admininstration in the rat: hemodynamicchanges studies by double-tracer autoradiogaraphy, Neurosurgery, 29, 19-26, 1991
285. Yoshioka S, Kochi M, Nagahiro S, Ushio Y, Shuntgraphy for functional evaluation of ventriculoperitoneal shunt in children, In Hydrocephalus-pathogenesis and treatment, ed by Matsumoto S
and Tamaki N, Springer-Verlag, 1991, pp473-48028286. Diksic M, Nagahiro S, Sourkes TL, Yamamoto YL

A new method to measure brain

serotonin thesis in vivo. I. Theory and basic data for a biological model., J Cereb Blood Flow
Metab, 10, 1-12, 1990
287. Diksic M, Nagahiro S, Sourkes TL, Biological model for the in vivo measurement of rate ofserotonin synthesis in the brain, J Neural Transm, 29, 131-140, 1990
288. Itoyama Y, Nagahiro S, Seto H, Sueyoshi N, Kuratsu J, Ushio Y, Brain metastasis from malignant
fibrous histiocytoma of the heart; case report, Neurosurgery, 26, 692-695, 1990
289. Nagahiro S, Takada A, Diksic M, Sourkes TL, Missala K, Yamamoto YL, A new method tomeasure brain serotonin synthesis in vivo. II. A practical autoradiographic method tested innormal and lithium-treated rats, J Cereb Blood Flow Metab, 10, 13-21, 1990
290. Nagahiro S, Diksic M, Yamamoto YL, Riml H, Non-invasive in-vivo autoradiographic method
to measure axonal transport in serotonergic neurons in the rat brain, Brain Res, 506, 120-128,
1990
291. Diksic M, Trani M, Nagahiro S, Synthesis of 6-{18F]fluoropyridoxal and radioactivity
distribution in rat at 60 min., Nucl Med Biol, 16, 413-418, 1989
292. Nishi T, Matsukado Y, Nagahiro S, Fukushima M, Koga K, Hemifacial spasm due tocontralateral acoustic neurinoma; case report, Neurology, 37, 339-342, 1987
293. Hirata Y

Matsukado Y, Nagahiro S, Kuratsu J, Intracerebral venous angioma with arterial

blood supply: a mixed angioma, Neurosurgery, 37, 227-232, 1986
294. Nagahiro S, Matsukado Y, Kuratsu J, Saito Y, Takamura S, Syringomyelia and syringobulbia
associated with an ependymoma of the cauda equina involving the conus medullaris; case report,
Neurosurgery, 18, 357-360, 1986
295. Yokota A, Matsukado Y, Fuwa I, Moroki K, Nagahiro S, Anterior basal encephalocele of theneonatal and inantile period, Neurosurgery, 19, 468-478, 1986
296. Kuratsu J, Matsukado Y, Hattori R, Nagahiro S, Immunopathological significance of IgG inmeningioma in relation to the pseudopsammoma bodies, Acta Neurochirurgica, 78, 38-42, 1985
297. Nagahiro S, Matsukado Y, Miura M, Yoshioka S, Cervical dermal sinus associated withmeningitis and motor paralysis, Brain & Development, 7, 504-507, 1985
298. Wada S, Matsukado Y, Nagahiro S, Urasaki E, Yatomi Y, Characteristics and generation sites of
wave

IV-V

complexinhuman

auditory

brain-stem

Electroencephalography and clinical, Neurophysiology, 61, 76, 1985

29

responses(ABBS)