---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------SAFETY DATA SHEET
Date Updated: Sep/27/2022---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------< 1 > Product and Company Information---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------RapidS
Product Name
PALM, Protein S-Palmitoylation Detection Kit
Code Number
F017B
Component
2× Binding BufferCompany
BioDynamics Laboratory Inc.
Address
9-7 Hongo 2-Chome, Bunkyo-Ku, Tokyo 113-0033 JAPANPhone+81-3-5803-9983
Fax+81-3-5684-6270---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------<2 > Hazards Identification (Evaluated as a single compound below (Sodium dodecyl sulfate))---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------Classification
Acute toxicity (Oral) (Category 4)
Acute toxicity (Skin) (Category 2)
Skin corrosive / Irritation (Category 2)
Serious eyes damage /Eyes irritation (Category 1)
Specification target internal organs / systemic toxicity (single exposure) (Category 1)
Specification target internal organs/systemic toxicity (repeat exposure) (Category 2)
Aquatic environmental toxicity: acute (Category 1, 3)
Symbol:Signal word
DangerHazard statement(s)H302: Harmful if swallowed
H310: Fatal in contact with skin
H315: Causes skin irritation.
H318: Causes serious eye damage.
H370: Causes damage to the following organs: central nervous system
H373: May cause damage to the following organs through prolonged or repeated exposure: liver
H400: Very toxic to aquatic life
H412: Harmful to aquatic life with long lasting effects.
Precautionary statement(s)P260: Do not breathe dust/fume/gas/mist/vapors/spray
P262: Do not get in eyes, on skin, orP264: Wash face, hands and any exposed skin thoroughly after
P270: Do not eat, drink or smoke when using this productP273: Avoid release to the environment.
P280: Wear protective gloves/protective clothing/eye protection/face protection
P330: Rinse mouth
P361: Remove/Take off immediately all contaminated clothing
P364: Wash contaminated clothing before reuse
P391: Collect spillage
P301+P312: IF SWALLOWED: Call a POISON CENTER or doctor/physician if you feel unwellP302+P352: IF ON SKIN: Gently wash with plenty of soap and water
1

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P305+P351+P338: IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do.
Continue rinsing. Immediately call a POISON CENTER/doctor.
P308+P313: IF exposed or concerned Call a POISON CENTER or doctor/physician
P332+P313: If skin irritation occurs: Get medical advice/attention
P405: Store locked up
P501: Dispose of contents/container to an approved waste disposal plant
Supplemental Hazard Statementsnone---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------< 3> Composition/Information on Ingredients---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------Component
2× Base Buffer
Description of the productMixture of substances listed below with nonhazardous additions
Hazardous Ingredient(s)Sodium dodecyl sulfate
CAS #: 151-21-3
Percent: 4 %Synonym: Sodium lauryl sulfate---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------< 4 > First Aid Measures (Sodium dodecyl sulfate)---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------EyeIf this chemical contacts the eyes, immediately wash the eyes with large amounts of water, occasionally lifting
the lower and upper lids. Consult a doctor immediately. Contact lenses should not be worn when working withthis chemical.
Skin
If this chemical contacts the skin, immediately flush the contaminated skin with water. If this chemical
penetrates the clothing, immediately remove the clothing and flush the skin with water. Get medical attention
promptly.
Breathing
If a person breathes large amounts of this chemical, move the exposed person to fresh air at once. If breathinghas stopped, perform mouth-to-mouth resuscitation. Keep the affected person warm and at rest. Consult adoctor as soon as possible.
Swallow
If this chemical has been swallowed, consult a doctor immediately.
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------< 5 > Fire-Fighting Measures (Sodium dodecyl sulfate)---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------Extinguishing Media
Water spray, Carbon dioxide, dry chemical powder or alcohol-resistant foam.
Protective Equipment
Wear self-contained breathing apparatus and protective suit.
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------< 6 > Accidental Release Measures (Sodium dodecyl sulfate)---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------Personal precautions
Chemical protection suit including self-contained breathing apparatus.
Methods For Cleaning Up
Sweep spilled substance into covered containers. Carefully collect remainder. Then store anddispose of according to local regulations.
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------< 7 > Handling and Storage---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------Handling
Wear appropriate protective gloves, clothing and goggles.
Storage
Keep tightly closed. Store at room temperature.
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------< 8 > Exposure Controls / Personal protection---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------Exposure Limits
Not available.
Wear appropriate protective eyeglasses or chemical safety goggles, protective gloves and protective lab coat. Use an approved
respirator. Safety shower and eye wash are required. Mechanical exhaust is needed to control exposure. Carry out according to goodindustrial hygiene and safety procedures, such as, wash thoroughly after handling, remove and wash contaminated clothing.
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------< 9 > Physical/Chemical Properties---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------Appearance
Form: Liquid
Boiling point/range
No data available
Melting point/range
No data available
2ver.1

Flash point
No data available
Auto Ignition Temp
No data available
Decomposition Temp
No data available
Water solubility
No data available---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------< 10 > Stability and Reactivity---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------Stability
Stable under recommended storage conditions.
Materials to Avoid
No information available.
Hazardous decomposition products
No information available.
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------< 11 > Toxicological Information (Sodium dodecyl sulfate)---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------Effective of short-term exposure:
The substance is irritating to the eyes, skin and respiratory tract.
Effective of long-term or repeated exposure: Repeated or prolonged contact with skin may cause dermatitis.
Inhalation
Sore throat. CoughSkinRedness.
Eyes
Pain. Redness.
Ingestion
Nausea. Vomiting. Diarrhoea.
Acute toxicity
LD50 Intraperitoneal - mouse - 250 mg/kg
LD50 Intravenous - mouse - 118 mg/kg
LD50 Intraperitoneal - rat - 210 mg/kg
LD50 Intravenous - rat - 118 mg/kg
LD50 Inhalation - rat – > 3900 mg/m3/1H
LD50 Oral - rat - > 1288 mg/kg---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------< 12 > Ecological Information (Sodium dodecyl sulfate)---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------This substance is toxic to aquatic organisms. It is strongly advised not to let the chemical enter into the environment.
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------< 13 > Disposal Considerations---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------Dispose of in accordance with local regulations.
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------< 14 > Transport Information---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------DOT Classification
Not regulated (United States).
IATA
Not regulated.
RID/ADR
Not regulated.
Special Provisions for Transport Not applicable.
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------< 15 > Regulatory Information---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------US State Regulations:
TSCA inventory Item
ListedSARA 313
No
California Proposition 65
No
Canadian Regulations:
DSL inventory ItemNDSL inventory Item

ListedNo

Japanese Government Regulations:Poisonous and Deleterious Substances Control Act
Industrial Safety and Health Act
PRTR

Not listed
Not listed
Listed: Class I Designated Chemical Substances

3ver.1

--------------------------------------------------------------------------------------------------------------------------------------------------------------------< 16 > Reference--------------------------------------------------------------------------------------------------------------------------------------------------------------------1) Japan CHEmicals Collaborative Knowledge database2) NITE Chemical Risk Information Platform)
3) THE MERCK INDEX 13TH EDITION
4) UNECE web page (GHS pictograms)--------------------------------------------------------------------------------------------------------------------------------------------------------------------< 17 > Other Information--------------------------------------------------------------------------------------------------------------------------------------------------------------------DISCLAIMER
For R&D use only. Not for drug, household or other uses.
WARRANTY
The above information is believed to be correct but does not purport to be all inclusive and shall be used only as a guide. The
information in this document is based on the present state of our knowledge and is applicable to the product with regard toappropriate safety precautions. It does not represent any guarantee of the properties of the product. Biodynamics Laboratory Inc.,
shall not be held liable for any damage resulting from handling or from contact with the above product.

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---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------SAFETY DATA SHEET
Date Updated: Sep/27/2022---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------< 1 > Product and Company Information---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------RapidS
Product Name
PALM, Additional Components for Affinity Purification
Code Number
F017B
Company
BioDynamics Laboratory Inc.
Address
9-7 Hongo 2-Chome, Bunkyo-Ku, Tokyo 113-0033 JAPANPhone+81-3-5803-9983
Fax+81-3-5684-6270---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------<2 > Hazards Identification---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------Classification
Flammable Liquid, Category 3
Symbol:Signal word: Danger
Hazard statement(s)H226 Flammable liquid and vapor.
Precautionary Statement(s)P210 Keep away from heat, sparks, open flames and hot surfaces. — No smoking.
P233 Keep container tightly closed.
P241 Use explosion-proof electrical, ventilating and lighting equipment.
P242 Use only non-sparking tools.
P243 Take precautionary measures against static discharge.
P280 Wear protective gloves, eye protection, protective clothing.
P303+P361+P353 If on skin (or hair): Take off immediately all contaminated clothing. Rinse skin with water/shower.
P370+P378 In case of fire: use regular dry chemical, carbon dioxide, water, or alcohol-resistant foam.
P403+P235 Store in a well-ventilated place. Keep cool.
P501 Dispose of contents in accordance with applicable local regulations.
Supplemental Hazard Statements: none---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------< 3> Composition/Information on Ingredients---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------Component:
Affinity Beads
Description of the product:

Mixture of substances listed below with nonhazardous additions

Hazardous Ingredient(s)Ethanol

CAS #: 64-17-5
Percent: 25%
Synonym: ethyl alcohol---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------< 4 > First Aid Measures---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------Inhalation
If adverse effects occur, remove to uncontaminated area. If not breathing, give artificial respiration or oxygen by5ver.1

qualified personnel. Seek immediate medical attention.
Rinse affected area with soap and water for at least 15 minutes. Seek medical assistance if necessary.
Immediately flush eyes, including under the eyelids with copious amounts of water for at least 15 minutes. Seek
immediate medical attention.
Ingestion
If a large amount is swallowed, get medical attention.
Most Important Symptoms/Effects, Acute and Delayed
Respiratory tract irritation, skin irritation, eye irritation, liver damage, and central nervous system depression.
Indication of any immediate medical attention and special treatment needed, if necessary
If any of the above symptoms are present, seek immediate medical attention.
No further relevant information available.
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------< 5 > Fire-Fighting Measures---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------Fire and Explosion Hazards
Severe fire hazard. Vapor is heavier than air. Vapors or gases may ignite at distant ignition sources
and flash back. Vapor/air mixtures are explosive above flash point. See Section 9, “Physical andChemical Properties” for flammability properties.
Extinguishing MediaSuitable: Regular dry chemical, carbon dioxide, fine water spray, and alcohol resistant foam.
Unsuitable: None listed.
Specific Hazards Arising from the Chemical
Thermal decomposition will form oxides of carbon.
Special Protective Equipment and Precautions for Fire-Fighters
Avoid inhalation of material or combustion byproducts. Wear full protective clothing and NIOSH
approved self-contained breathing apparatus (SCBA).
NFPA Ratings (0 = Minimal; 1 = Slight; 2 = Moderate; 3 = Serious; 4 = Severe)
Health = 2 Fire = 3 Reactivity = 0---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------< 6 > Accidental Release Measures---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------Personal Precautions, Protective Equipment and Emergency Procedures
Immediately contact emergency personnel. Keep unnecessary personnel away. Use suitable protective equipment; see
Section 8, “Exposure Controls and Personal Protection”.
Methods and Materials for Containment and Clean up
Do not touch spilled material. Notify safety personnel of spills. Absorb with sand or other non-combustible material. Collectspilled material in appropriate container for disposal. Isolate hazard area and deny entry.
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------< 7 > Handling and Storage---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------Safe Handling Precautions
See Section 8, “Exposure Controls and Personal Protection”. Handle glass ampoules with care.
Storage
Store and handle in accordance with all current regulations and standards. Sealed ampoules, as
received, should be stored in the dark at temperatures between 10 °C and 30 °C. Keep separated
from incompatible substances.
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------< 8 > Exposure Controls / Personal protection---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------Exposure Limits
OSHA (PEL): 1000 ppm TWA or 1900 mg/m3 TWA
ACGIH (TLV): 1000 ppm STELNIOSH (REL): 1000 ppm TWA or 1900 mg/m3 TWA
3300 ppm IDLH (10 % LEL)
Engineering Controls
Provide local exhaust or process enclosure ventilation system. Ensure compliance with applicableexposure limits.
Personal Protection
In accordance with OSHA 29 CFR 1910.132, subpart I, wear appropriate Personal Protective
Equipment (PPE) to minimize exposure to this material.
Respiratory Protection
If workplace conditions warrant a respirator, a respiratory protection program that meets OSHA
29CFR 1910.134 must be followed. Refer to NIOSH 42 CFR 84 for applicable certified respirators.
Eye/Face Protection
Wear splash resistant safety goggles with a face shield. An eye wash station should be readily
available near areas of use.
Skin and Body Protection
Personal protective equipment for the body should be selected based on the task being performed
and the risks involved and should be approved by a specialist before handling this product.
Chemical-resistant gloves should be worn at all times when handling chemicals.
Skin Contact
Eye Contact

6ver.1

---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------< 9 > Physical/Chemical Properties---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------Appearance
Form: Suspension
Molecular FormulaC2H5OH
Molar Mass (g/mol)
46.07
Odorvinous
Odor threshold
5 ppm to 10 ppm
pH
not available
Evaporation rate (CCl4 = 1)
1.4
Melting point/freezing point (ºC)
–117 (–179 ºF)
Density (g/mL)
0.78775 at 20 ºCSpecific Gravity (water = 1)
0.7893
Vapor Pressure (mmHg)
40 at 19 ºC
Vapor Density (air = 1)
1.59
Viscosity (cP)
1.22 to 1.41 at 20 ºC
Solubility(ies)benzene, ether, acetone, chloroform, organic solvents
Partition coefficient (n-octanol/water):
not available
Autoignition Temperature (ºC)
363 (685 ºF)
Thermal Decomposition (ºC)
not applicable
Initial boiling point and boiling range (ºC)
78.3 to 78.5 (173 ºF)
Explosive Limits, LEL (Volume %)3.3
Explosive Limits, UEL (Volume %)19Flash Point (ºC)
13 ºC (TCC)
Flammability (solid, gas)
not applicable---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------< 10 > Stability and Reactivity---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------Reactivity
Stable at normal temperatures and pressure.
Stability
StablePossible Hazardous Reactions
None listed.
Conditions to Avoid
Avoid heat, flames, sparks and other sources of ignition. Ampoules may rupture or
explode if exposed to heat.
Incompatible Materials
Acids, bases, combustible materials, halo carbons, halogens, metal oxides, metal salts,metals, oxidizing materials, peroxides.
Fire/Explosion Information
See Section 5, “Fire Fighting Measures”.
Hazardous Decomposition
Thermal decomposition will produce oxides of carbon.
Hazardous Polymerization
Will Not Occur---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------< 11 > Toxicological Information---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------For EthanolInhalation
Ethanol may cause irritation of mucous membranes, headache, drowsiness, fatigue, nervousness,dullness, narcosis, lack of concentration, somnolence, and symptoms of drunkenness. Reproductive
effects have been reported in animals.
Skin Contact
Ethanol may cause irritation, mild redness and burning, sensitization, allergic, contact dermatitis.
Chronic exposure to ethanol may result in defatting of the skin.
Eye Contact
Ethanol may cause irritation, conjunctivitis, and corneal cloudiness. Vapors exposure at sufficiently
high concentrations may cause stinging and watering of the eye.
Ingestion
Ethanol short term exposure may cause headache, drowsiness, emotional lability, decreased
inhibitions, exhilaration, boastfulness, talkativeness, remorse, belligerency, gradual visualimpairment, muscular incoordination, slurring of speech, and symptoms of drunkenness; long term
exposure may result in liver damage. Reproductive effects have been reported in animals.
Acute ToxicityNot classified.
Ethanol, Rat, Oral LD50: 7060 mg/kg
Rat, Inhalation LC50: 124.7 mg/L (4 h)Skin Corrosion/Irritation
Not classified.
Ethanol, Rabbit skin, moderate: 20 mg (24 h)
Human skin: 70 %7ver.1

Serious Eye damage/Eye irritation Not classified.
Ethanol, Rabbit eyes, mild: 500 mg (24 h)
Rabbit eyes, severe: 500 mg
Respiratory Sensitization
No data available.
Skin Sensitization
No data available.
Germ Cell Mutagenicity
Not classified.
Human, 15 mmol/L (24 h), 100 mmol/L (3 h)Carcinogenicity
Not classified, this SRM is not for human consumption.
Reproductive Toxicity
Not classified.
Rat, Oral TDLo: 112 mg/kg (14 d)
Human, Oral TDLo (37 weeks pregnant): 250 mg/kg
Listed as a Carcinogen/Potential Carcinogen
No
IARC lists ethanol (as related to alcoholic beverages) as Group 1(carcinogenic to humans).
Specific Target Organ Toxicity, Single Exposure
Not classified.
Specific Target Organ Toxicity, Repeated Exposure
Not classified.
Aspiration Hazard
No data available.
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------< 12 > Ecological Information---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------Ecotoxicity Data
Rainbow trout (Oncorhynchus mykiss) LC50 (static): 12.0 mL/L to 16.0 mL/L (96 h)
Fathead minnow (Pimephales promelas) LC50 (static): >100 mg/L (96 h)
Freshwater water flea (Daphnia magna) EC50 (static): 2 mg/L (48 h)
Persistence and Degradability
No data available.
Bioaccumulative Potential
No data available.
Mobility in Soil
No data available.
Other Adverse effects
No data available.
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------< 13 > Disposal Considerations---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------Dispose of in accordance with local regulations.
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------< 14 > Transport Information---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------U.S. DOT and IATA: UN1170, Ethanol, Hazard Class 3, Packing Group III, Excepted Quantities E1.
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------< 15 > Regulatory Information---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------US State Regulations:
TSCA inventory Item
ListedSARA Title III Sections 311/312 Hazardous Categories (40 CFR 370.21)
ACUTE HEALTH: Yes.
CHRONIC HEALTH: Yes.
FIRE: Yes.
REACTIVE: No.
PRESSURE: No
California Proposition 65
Warning!
This product contains a chemical (ethanol) known to
the state of California to cause cancer andreproductive/developmental effects.
Canadian Regulations:
DSL inventory ItemNDSL inventory Item

NoNo

Japanese Government Regulations:Poisonous and Deleterious Substances Control Act
Industrial Safety and Health Act

Not listed
Notifiable Substances (Law Art.57, Enforcement
Oder Art.18) - Ethanol
Notifiable Substances (Law Art.57-2, Enforcement
8ver.1Oder Art.18-2 AttachedTableNo.9) - Ethanol
PRTRNot listed---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------< 16 > Reference---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------1) ChemAdvisor, Inc., MSDS, Ethyl Alcohol, 09 December 2015.
2) Hazardous Substances Data Bank, National Library of Medicine, Ethanol, CAS# 64-17-5, Full Record, available at
http://toxnet.nlm.nih.gov/ (accessed Aug 2017).
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------< 17 > Other Information---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------DISCLAIMER
For R&D use only. Not for drug, household or other uses.
WARRANTY
The above information is believed to be correct but does not purport to be all inclusive and shall be used only as a guide. The
information in this document is based on the present state of our knowledge and is applicable to the product with regard to
appropriate safety precautions. It does not represent any guarantee of the properties of the product. Biodynamics Laboratory Inc.,
shall not be held liable for any damage resulting from handling or from contact with the above product.

9ver.1