4th World Congress on

Targeting Mitochondria
October 17-18, 2013- Hotel Ritz Carlton, Berlin – Germany

Final Agenda

Day 1 – October 17, 2013
7h30

Opening of Registrations

9h00

Opening Ceremony by Targeting Mitochondria 2013 Chairmen: Marvin Edeas – Volkmar Weissig

9h10

General Introduction of Targeting Mitochondria 2013: Huge Steps to New Medicine
Douglas Wallace, Center of Mitochondrial and Epigenomic Medicine, Philadelphia, USA

Session 1: Recent Advances on Mitochondrial Dysfunctions in Chronic Diseases
Chairmen: Volkmar Wessig, Douglas Wallace, Marvin Edeas
9h45

Structural Classification as a Platform for Predicting the Function of Mitochondrial Mutations
Rhiannon Lloyd, Institute of Biomedical and Biomolecular Sciences, University of Portsmouth, United Kingdom

10h15

Targeting Small-Conductance Calcium-Activated Potassium (SK2) Mitochondrial Channels:
A Promising Target for Neuroprotective Strategies
Carsten Culmsee, Philipps University of Marburg, Marburg, Germany

10h45 Coffee Break, Posters Session & Exhibition Space Visit

11h15

Mitochondrial Dysfunction Modifies Stem Cell Function
Riikka Hamalainen, University of Helsinki, Helsinki, Finland

Session 2: Devices, Methods & Mitochondria: Innovations & New OpportunitiesChairmen: Rodrigue Rossignol, Douglas Wallace
11h45

Nanofluidic Platform for Single Mitochondria Analysis using Fluorescence Microscopy
Douglas Wallace, Center of Mitochondrial and Epigenomic Medicine, Philadelphia, USA

12h00

mTRIP, a Novel Imaging Tool to Diagnose in situ Mitochondrial DNA Processing Dysfunction
Laurent Chatre, Pasteur Institute, Paris, France

12h30 Lunch Break, Posters Session & Exhibition Space Visit

14h00

A Yeast-based Assay to Identify Drugs Active against Human Mitochondrial Disorders
Jean-Paul di Rago, CNRS, Bordeaux, France

14h30

Carbon Nanotubes for Mitochondrial Targeting: State of the Art & Strategies
Alessia Battigelli, CNRS, Strasbourg, FranceSession 3: Strategies to Target Mitochondria:
Recent Clinical Data and Potential Therapeutic Studies- Part 1 Chairmen: Jiri Neuzil, Rifaat Safadi, Heinz Osiewacz
15h00

Mitochondria & Liver: State of the Art & Perspectives
Rifaat Safadi, Hadassah Hebrew University Hospital, Jerusalem, Israel

15h30 Coffee Break, Posters Session & Exhibition Space Visit

16h00

Liver, Oxidative Stress & Mitochondria: The Subtle Balance
José C. Fernandez-Checa, Spanish National Research Council, Barcelona, Spain

16h30

Damaged Mitochondrial DNA, a Novel Putative Target for Treatment of Diabetic Complications and otherDiseases of Mitochondrial Dysfunction
Afshan Malik, King’s College London, London, United Kingdom

16h40

The Measurement of Nitrotyrosine in Blood as an Early Predictive Parameter of Nitrosative Stressand Functional Mitochondriopathy
Clauss Muss, St. Elisabeth Universität für Forschung und Soziales, Bratislava, Slovakia

16h50

Cutaneous Respirometry in Healthy Volunteers: A Novel Technique for Monitoring Mitochondrial
Function
Floor A. Harms, Erasmus MC, University Medical Center, Rotterdam, The Netherlands

17h00

Melanin Reduces Acute Mitochondrial Superoxide Generation: A Real-Time Amperometric Study
Sarah Jayne Boulton, Institute of Cellular Medicine, Newcastle, United Kingdom

17h10

The Mitosafe Bioenergetic Balance Screening (BBS): An Innovative Method to Profile Modulators of the
Mitochondrial Metabolic Functions
Emilie Cornille-Robert, ICDD, Predictive Toxicity Department, Meyreuil, France

17h20

Calcium co-Regulates Oxidative Metabolism and ATP-Synthase Dependent Respiration in Pancreatic
Beta-Cells
Umberto De Marchi, Nestlé Institute of Health Sciences, Lausanne, Switzerland

17h30

Changed Mitochondrial Properties after Expression of Ciona Intestinalis Alternative Oxidase(Aox) in Mouse Heart
Frank N. Gellerich, Otto-Von-Guericke University, Magdeburg, Germany

17h40

Oxidative Stress alters Mitochondrial Dynamics at the Nodes of Ranvier in ex vivo transected Axons
Elena Bros, Institute For Medical Immunology, Charité-Universitätmedizin Berlin, Germany

17h50

Stomatin-Like Protein-2 Modulates Cell Function by Regulating Mitochondrial Membrane
Compartmentalization and Respiration
Joaquín Madrenas, Microbiome and Disease Tolerance Centre, Mcgill University, Montreal, Canada

18h00

Characterization of Proteins involved in RNA Trafficking into Human Mitochondria
Ali Gowher, University of Strasbourg - CNRS, Strasbourg, France

18h10

End of the First Day

19h45

Targeting Mitochondria 2013 DinnerThe Dinner will be held at Ritz Carlton Hotel. If you wish to register, please contact the conference staff.

2Day 2 – October 18, 2013
Session 3: Strategies to Target Mitochondria:
Recent Clinical Data and Potential Therapeutic Studies- Part 2 –Chairmen: Carsten Culmsee, Keshav Singh, Marvin Edeas, Volkmar Weissig
9h00

Role of Mitochondrial Quality Control in Aging: An Integrated Network of Pathways
Heinz Osiewacz, Johann Wolfgang Goethe University, Frankfurt, Germany

9h30

Targeting Muscle Mitochondria with Vitamin D: Strategies and Perspectives
Timothy Cheetham, University of Newcastle, Newcastle, United Kingdom

10h00

Cancer & Mitochondria: Therapeutics Strategies
Jiri Neuzil, Griffith Health Institute, Southport, Australia
10h30 Coffee Break, Posters Session & Exhibition Space Visit

11h00

Mitochondrial Uncoupling Proteins and its Role in Cancer
Keshav Singh, University of Alabama, Birmingham, USA

11h30

Mitochondria-Targeting Strategies in Cancer Bioenergetic Therapies: Recent Advances & Perspectives
Rodrigue Rossignol, University of Bordeaux, Bordeaux, France

12h00

Effects of Oral Supplementation with Sanomit on Tinnitus-Induced Distress: Double Blind, Randomized,
Placebo-Controlled Study
Agnieszka J. Szczepek, Charité – Universitätsmedizin, Berlin, Germany

12h30

New Antioxidant Product on Market to Target Mitochondria: Presentations and Results
Vladimir Skulachev, Moscow University, Moscow, Russia®

12h45 Lunch Break, Posters Session & Exhibition Space Visit
14h00

Impact of Antioxidants on Mitochondria in Primary Cells and in Cancer-derived Cell Lines
Miria Ricchetti, Pasteur Institute, Paris, France

14h30Mitochondria-Specific Genistein Lipidic Nanocarriers
Tamer Elbayoumi, Midwestern University, College, Glendale, USA

14h40

HB229: A Novel Parkin-Independent Inducer of Mitophagy
Michelangelo Campanella, RVC and UCL Consortium for Mitochondrial Research, London, United Kingdom

14h50

Low Abundance of the Matrix Arm of Complex I in the Mitochondria Predicts Longevity
Thomas Von Zglinicki, Institute for Ageing and Health, Newcastle University, Newcastle, United Kingdom

15h00

Targeting Mitochondria of Cancer Cells With Dichloroacetate: The Case of Oral Squamous Cell Carcinoma
Vitalba Ruggieri, I.R.C.C.S. Centro Di Riferimento Oncologico Della Basilicata, Rionero In Vulture, Italy

15h10

Selective Mitochondrial Targeting for Anxiolytic Treatment
Michaela Filiou, Max Planck Institute of Psychiatry, Munich, Germany

15h20

An Immunomodulating Fatty Acid Analogue Targeting Mitochondria Exerts Anti-Atherosclerotic
Effect beyond Plasma Cholesterol-Lowering Activity in apoe-/-Mice
Rolf Berge, Department of Clinical Science, University of Bergen, Bergen, Norway

15h30

Bornavirus X Protein: A New Tool against Neurodegenerative Disorders?
Marion Szelechowski, INSERM, CHU Purpan, Toulouse, France

15h40Targeting Mitochondria 2013 Discussion
The scientific committee will discuss the axes of the next upcoming Targeting Mitochondria World Congress 2014.
One of the strategic axes will be Modulation Diversity & Variety of Microbiota by Mitochondria.
Conclusion of Targeting Mitochondria 2013
Targeting Mitochondria Awards

16h10

All together around Drink & Snacks

16h30

End of Targeting Mitochondria 20133