病態分子イメージングセンターに係る業績
講座等名

分子遺伝学部門

事業推進者名木梨達雄＜雑誌論文＞（著者名・論文標題・雑誌名・レフェリー有無・巻・ページ・発行年）
（原著）
1.

2.

Y Konishi, K Terai, Y Furuta, H Kiyonari, T Abe, Y Ueda, T Kinashi, Y Hamazaki, A
Takaori-Kondo, M Matsuda, Live-Cell FRET Imaging Reveals a Role of Extracellular
Signal-Regulated Kinase Activity Dynamics in Thymocyte Motility, iScience, Volume 10, 21
December 2018, Pages 98-113 レフェリー有D Bogdanova, A Takeuchi, M Ozawa, Y Kanda, M. A. Rahman, B Ludewig, T Kinashi and TKatakai, Essential Role of Canonical NF-κB Activity in the Development of Stromal Cell
Subsets in Secondary Lymphoid Organs, J. Immunol. December 15, 2018, 201 (12) 3580-3586

レフェリー有3.

4.

Konagaya Y, Terai K, Hirao Y, Takakura K, Imajo M, Kamioka Y, Sasaoka N, Kakizuka A,Sumiyama K, Asano T, Matsuda M A Highly Sensitive FRET Biosensor for AMPK Exhibits
Heterogeneous AMPK Responses among Cells and Organs,
Cell reports
201721(9):2628-2638 レフェリー有Mouri Y, Ueda Y, Yamano T, Matsumoto M, Tsuneyama K, Kinashi T, Matsumoto M,Modeof Tolerance Induction and Requirement for Aire Are Governed by the Cell Types That Express
Self-Antigen and Those That Present Antigen, J. immunol., 2017 199(12):3959-3971 レフェリー有5.

Kondo N, Ueda Y, Kita T, Ozawa M, Tomiyama T, Yasuda K, Lim DS, Kinashi T.
NDR1-dependent regulation of kindlin-3 controls high-affinity LFA-1 binding and immune
synapse organization. Mol Cell Biol. 2017 Jan 30. pii: MCB.00424-16. doi:
10.1128/MCB.00424-16. [Epub ahead of print]
レフェリー有＜図書＞（著者名・出版社・書名・発行年・総ページ数）
該当なし＜学会発表＞（発表者名・発表標題・学会名・開催地（海外の場合は匡名と都市名）・発表年月）
1. T Kinashi, Roles of Rap1 signaling in immunodeficiency and autoimmunity. The 9th AsianCongress of Pediatric Infectious Diseases (ACPID) Dec 2nd. 2018. Fukuoka. （国際学会 招待講演）
2. T Kinashi, N Kondo, Y Ueda, Y Kamioka, Rap1 signaling to NDR1 kinase regulate immune
synapse formation and cell polarity. The 9th Xiamen Winter Symposium, The Hippo
Signaling Pathway in Development and Disease Nov.2－5 2018. Xiamen. China. （国際学会招待講演）
3. Y Ueda, N Kondo, Y Kamioka and T Kinashi, Regulation of cell polarization by NDR1 andRab8 upon chemokine stimulation. The 9th Xiamen Winter Symposium, The Hippo Signaling
Pathway in Development and Disease Nov.2－5 2018. Xiamen. China.（国際学会 ポスター発表）
4. N Kondo, T Kinashi, LFA-1 を介したリンパ球細胞接着の一分子解析（3P-0061）分子生物学会,
2018 . Nov. 28-30 Yokohama
5. Y Ueda, N Kondo, Y Kamioka, T Kinashi, W747 talin1 binding site in cytoplasmic domain ofthe integrin beta2 subunit is crucial for Tcell migration and activation (2-A-WS14-2-O/P), The
47th Annual Meeting of the Japanese Society for Immunology 2018 . Dec 10-12 Fukuoka
6. Y Kamioka, Y Ueda, N Kondo, T Kinashi, Roles of Rap1, Talin-1 and Kindlin-3 in lymphocyte
homing to peripheral and mucosal lymph nodes (2-A-WS14-4-O/P), The 47th Annual Meetingof the Japanese Society for Immunology 2018. Dec 10-12 Fukuoka
7. T Fukuhara, Intravital observation system of the colon by two photon excitation microscopy,Inflammatory Bowel Diseases 2018 - 13th Congress of ECCO, 2018 Feb. Vienna, Austria
8. Kondo N, Ueda Y, Kinashi T, NDR1 acts as a molecular hub for the organization of

immunological synapse (3-I-W42-12-O/P), The 46th Annual Meeting of the Japanese Societyfor Immunology 2017. 12.12-12.14 Sendai.
9. Ueda Y, Kondo N, Kamioka Y, Kinashi T, Regulation of cell polarization by Rap1 via
NDR/Rab8 axis upon chemokine stimulation(1-G-W13-21-P), The 46th Annual Meeting of theJapanese Society for Immunology 2017. 12.12-12.14 Sendai.
10. Kamioka Y, Ueda Y, Kondo N, Kinashi T, Roles of Rap1 and Kindlin-3 in lymphocyte homing toperipheral lymph nodes (3-I-W42-10-O/P), The 46th Annual Meeting of the Japanese Society
for Immunology2017. 12.12-12.14 Sendai.
＜特許申請・取得状況＞
該当なし