SAFETY DATA SHEETS
Invivoscribe® RNA Sensitivity Panels

Catalog Number

Description

40870030

Sensitivity Panel - IVS-0003 Clonal Control RNA

40870110

Sensitivity Panel - IVS-0011 Clonal Control RNA

40870150

Sensitivity Panel - IVS-0015 Clonal Control RNA

40870200

Sensitivity Panel - IVS-0020 Clonal Control RNA

40870320

Sensitivity Panel - IVS-0032 Clonal Control RNA

SDS – RNA Sensi�vity Panels (CLP)-EN Rev. A | December 2023

1 / 10SAFETY DATA SHEETThis safety data sheet was created pursuant to the requirements of:Regula�on (EC) No. 1907/2006 as amended by Commission Regula�on (EU)2020/878 and Regula�on (EC) No. 1272/2008
Issuing Date 27-Apr-2023

0B

Revision Date 27-Apr-2023

Revision Number 1

SECTION 1: Iden�ﬁca�on of the substance/mixture and of the company/undertaking

43B

1.1.

Product iden�ﬁer
Product Code(s)Product Name

Synonyms

40830240

100% IVS-0003 Sensi�vity RNA

None40830250

10-1 IVS-0003 Sensi�vity RNA

None4083026010-2 IVS-0003 Sensi�vity RNA

None4083027010-3 IVS-0003 Sensi�vity RNA

None40830280

10-4 IVS-0003 Sensi�vity RNA

None4083029010-5 IVS-0003 Sensi�vity RNA

None40830300

10-6 IVS-0003 Sensi�vity RNA

None40830800

100% IVS-0011 Sensi�vity RNA

None4083081010-1 IVS-0011 Sensi�vity RNA

None40830820

10-2 IVS-0011 Sensi�vity RNA

None40830830

10-3 IVS-0011 Sensi�vity RNA

None40830840

10-4 IVS-0011 Sensi�vity RNA

None40830850

10-5 IVS-0011 Sensi�vity RNA

None40830860

10-6 IVS-0011 Sensi�vity RNA

None40831080

100% IVS-0015 Sensi�vity RNA

None40831090

10-1 IVS-0015 Sensi�vity RNA

None40831100

10-2 IVS-0015 Sensi�vity RNA

None4083111010-3 IVS-0015 Sensi�vity RNA

None40831120

10-4 IVS-0015 Sensi�vity RNA

None4083113010-5 IVS-0015 Sensi�vity RNA

None40831140

10-6 IVS-0015 Sensi�vity RNA

None40831430

100% IVS-0020 Sensi�vity RNA

None40831440
40831450

10-1 IVS-0020 Sensi�vity RNA

None

10-2 IVS-0020 Sensi�vity RNA

None40831460

10-3 IVS-0020 Sensi�vity RNA

None4083147010-4 IVS-0020 Sensi�vity RNA

None40831480

10-5 IVS-0020 Sensi�vity RNA

None40831490

10-6 IVS-0020 Sensi�vity RNA

None40832270

100% IVS-0032 Sensi�vity RNA

None40832280

10-1 IVS-0032 Sensi�vity RNA

None4083229010-2 IVS-0032 Sensi�vity RNA

None40832300

10-3 IVS-0032 Sensi�vity RNA

None40832310

10-4 IVS-0032 Sensi�vity RNA

None4083232010-5 IVS-0032 Sensi�vity RNA

None40832330

10-6 IVS-0032 Sensi�vity RNA

None

Pure substance/mixture
16B

1.2.

MixtureRelevant iden�ﬁed uses of the substance or mixture and uses advised against

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SECTION 1: Iden�ﬁca�on of the substance/mixture and of the company/undertaking
Recommended use
Uses advised against

17B

1.3.

Assay reagent
For professional use only

Details of the supplier of the safety data sheet
Importer
Invivoscribe Technologies
Zeppelinstrasse 185399 Hallbergmoos
Germany
Phone: +49 89 904 299 800

Supplier
Invivoscribe, Inc.
10222 Barnes Canyon Rd
Bldg. 1San Diego, CA 92121
Phone: +1 858-224-6600

Distributor
Invivoscribe Technologies, SARL
c/o Ficorec Domicilia�on Services
132, Boulevard Michelet
Hall Nord – 5ème étage
13008 Marseille
FRANCE
Tel: +33 (0)4 42 01 78 10

For further informa�on, please contact
E-mail address
customerservice@invivoscribe.com
18B

1B

1.4.

Emergency telephone number
Emergency telephone+49 89 904 299 800 (M-F 8:00 – 16:30 CET)Emergency telephone - §45 - (EC)1272/2008
Europe112

SECTION 2: Hazards iden�ﬁca�on
2.1.

Classiﬁca�on of the substance or mixture
Classiﬁcation according to Regulation (EC) No. 1272/2008 [CLP]This substance is classiﬁed as not hazardous according to regula�on (EC) 1272/2008 [CLP].

2.2.

Label elements
Hazard statements

44B

Not classiﬁed.
Unknown aqua�c toxicity
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2B

2.3.

Other hazards
No informa�on available.
Endocrine Disruptor
Informa�on

Contains 0 % of components with unknown hazards to the aqua�c environment.

This product does not contain any known or suspected endocrine disruptors.

SECTION 3: Composi�on/informa�on on ingredients

45B

3.1

Substances
The product contains no substances which at their given concentra�on, are considered to be hazardous to health.
Full text of H- and EUH-phrases: see sec�on 16
Acute Toxicity Estimate
If LD50/LC50 data is not available or does not correspond to the classiﬁcation category, then the appropriate conversion value from
CLP Annex I, Table 3.1.2, is used to calculate the acute toxicity estimate (ATEmix) for classifying a mixture based on its components
This product does not contain candidate substances of very high concern at a concentra�on >=0.1% (Regula�on (EC) No. 1907/2006(REACH), Ar�cle 59)

3B

SECTION 4: First aid measures

46B

4.1.

Descrip�on of ﬁrst aid measures

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SECTION 4: First aid measures
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60B

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4.2.

Inhala�on
Eye contact
Skin contact
Inges�on

Remove to fresh air. Get medical aten�on if symptoms occur.
Rinse thoroughly with plenty of water for at least 15 minutes, li�ing lower and upper eyelids. Consult
a physician.
Wash skin with soap and water. Get medical aten�on if symptoms occur.
Do NOT induce vomi�ng. Never give anything by mouth to an unconscious person. Rinse mouth. Get
medical aten�on if symptoms occur.

Most important symptoms and eﬀects, both acute and delayed
Symptoms
None known.
Eﬀects of Exposure
No informa�on available.
63B

64B

21B

4.3.

Indica�on of any immediate medical aten�on and special treatment needed
Note to physicians
Treat symptoma�cally.
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SECTION 5: Fireﬁgh�ng measures

47B

5.1.

Ex�nguishing media
Suitable Ex�nguishing MediaUse ex�nguishing measures that are appropriate to local circumstances and thesurrounding environment.
No informa�on available.

66B

67B

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5.2.

Unsuitable ex�nguishing media

Special hazards arising from the substance or mixture
Speciﬁc hazards arising from the chemical
No informa�on available.
68B

23B

5.3.

Advice for ﬁreﬁghters
Special protec�ve equipment andprecau�ons for ﬁre-ﬁghters

Fireﬁghters should wear self-contained breathing apparatus and full ﬁreﬁgh�ng
turnout gear. Use personal protec�on equipment.

69B

5B

SECTION 6: Accidental release measures

48B

6.1.

Personal precau�ons, protec�ve equipment and emergency procedures
Personal precau�ons
Ensure adequate ven�la�on.
For emergency responders
Use personal protec�on recommended in Sec�on 8.
70B

71B

24B

6.2.

Environmental precau�ons
Environmental precau�ons
72B

25B

6.3.

See Sec�on 12 for addi�onal Ecological Informa�on.

Methods and material for containment and cleaning up
Methods for containment
Prevent further leakage or spillage if safe to do so.
Methods for cleaning up
Dam up. Soak up with inert absorbent material. Take up mechanically, placing in appropriate
containers for disposal.
Preven�on of secondary hazards
Clean contaminated objects and areas thoroughly observing environmental regula�ons.
73B

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75B

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6.4.

Reference to other sec�ons
Reference to other sec�ons
76B

6B

See sec�on 8 for more informa�on See sec�on 13 for more informa�on

SECTION 7: Handling and storage

49B

7.1.

Precau�ons for safe handling
Advice on safe handling
General hygiene considera�ons
77B

78B

27B

7.2.

Handle in accordance with good industrial hygiene and safety prac�ce.
Handle in accordance with good industrial hygiene and safety prac�ce.

Condi�ons for safe storage, including any incompa�bili�es

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SECTION 7: Handling and storage
Storage Condi�ons
Storage class (TRGS 510)

Keep containers �ghtly closed in a dry, cool and well-ven�lated place.
Storage class 10.

Speciﬁc end use(s)Speciﬁc use(s)The iden�ﬁed uses for this product are detailed in Sec�on 1.2.

79B

80B

28B

7.3.

81B

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SECTION 8: Exposure controls/personal protec�on

50B

8.1.

Control parameters
Exposure Limits
82B

This product, as supplied, does not contain any hazardous materials with occupa�onal exposure
limits established by the region speciﬁc regulatory bodies.

Biological occupa�onal exposure limits
This product, as supplied, does not contain any hazardous materials with biological limits established by the region-speciﬁc regulatory
bodies.
Derived No Eﬀect Level (DNEL) - Workers
No informa�on available.
Derived No Eﬀect Level (DNEL) - General Public
No informa�on available.
Predicted No Eﬀect Concentra�on (PNEC)
No informa�on available.
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8.2.

Exposure controls
Engineering controls
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8B

Showers
Eyewash sta�ons
Ven�la�on systems.

Personal protec�ve equipment
Eye/face protec�on
Hand protec�on
Skin and body protec�on
Respiratory protec�onGeneral hygiene considera�ons
Environmental exposure controls

Wear safety glasses with side shields (or goggles). Eye protec�on must conform to standard EN
166.
Wear suitable gloves. Gloves must conform to standard EN 374.
Wear suitable protec�ve clothing. (EN ISO 6529).
No protec�ve equipment is needed under normal use condi�ons. If exposure limits are
exceeded or irrita�on is experienced, ven�la�on and evacua�on may be required.
Handle in accordance with good industrial hygiene and safety prac�ce.
No informa�on available.

SECTION 9: Physical and chemical proper�es

51B

9.1.

Informa�on on basic physical and chemical proper�es
Appearance
Physical state
LiquidColor
Colorless
Odor
Odorless
Odor thresholdNo informa�on available
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95B

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PropertyMel�ng point / freezing pointIni�al boiling point and boiling range
Flammability
Flammability Limit in Air
Upper ﬂammability or explosive limits
Lower ﬂammability or explosive limits
Flash point
Autoigni�on temperature
Decomposi�on temperature
SDS – RNA Sensi�vity Panels (CLP)-EN Rev. A | December 2023

ValuesRemarks • Method
No data available
No data available
No data available
No data available
No data available
No data available
No data available
No data available
No data available
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SECTION 9: Physical and chemical proper�espHNo data available
No data available
No data available
No data available
No data available
No data available
No data available
No data available
No data available
No data available
No data available
No data available
No data available
No data available
No data available

pH (as aqueous solu�on)
Kinema�c viscosity
Dynamic viscosity
Water solubility
Solubility(ies)Par��on coeﬃcient
Vapor pressure
Rela�ve density
Bulk density
Liquid density
Rela�ve vapor densityPar�cle characteris�cs
Par�cle sizePar�cle size distribu�on
30B

9.2.

Other informa�on
9.2.1.
9.2.2.

9B

Information with regard to physical hazard classes
Not applicable
Other safety characteristics
No informa�on available

SECTION 10: Stability and reac�vity

52B

10.1. Reac�vity
Reac�vity

None under normal use condi�ons.

99B

31B

10.2. Chemical stability
Stability
Explosion data

Stable under normal condi�ons.

100B

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32B

Sensi�vity to mechanical impact

None.

Sensi�vity to sta�c discharge

None.

10.3. Possibility of hazardous reac�ons
Possibility of hazardous reac�ons

None under normal processing.

10.4. Condi�ons to avoid
Condi�ons to avoid

None known based on informa�on supplied.

10.5. Incompa�ble materials
Incompa�ble materials

None known based on informa�on supplied.

10.6. Hazardous decomposi�on products
Hazardous decomposi�on products

None known based on informa�on supplied.

104B

33B

105B

34B

106B

35B

107B

10B

53B

SECTION 11: Toxicological informa�on
11.1. Informa�on on hazard classes as deﬁned in Regula�on (EC) No 1272/2008
Informa�on on likely routes of exposure
Product Informa�on
Inhala�on
Speciﬁc test data for the substance or mixture is not available.
108B

109B

110B

Eye contact

Speciﬁc test data for the substance or mixture is not available. Contact with eyes may cause irrita�on.

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SECTION 11: Toxicological informa�on
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112B

Skin contact

Speciﬁc test data for the substance or mixture is not available.

Inges�on

Speciﬁc test data for the substance or mixture is not available.

Symptoms related to the physical, chemical and toxicological characteris�cs
Symptoms
None known.
Acute toxicity
Numerical measures of toxicity
Based on available data, the classiﬁca�on criteria are not met.
Component Informa�on
Delayed and immediate eﬀects as well as chronic eﬀects from short and long-term exposure
Skin corrosion/irrita�on
Based on available data, the classiﬁca�on criteria are not met.
Serious eye damage/eye irrita�on
Based on available data, the classiﬁca�on criteria are not met.
Respiratory or skin sensi�za�on
Based on available data, the classiﬁca�on criteria are not met.
Germ cell mutagenicity
Based on available data, the classiﬁca�on criteria are not met.
Carcinogenicity
Based on available data, the classiﬁca�on criteria are not met.
Reproduc�ve toxicity
Based on available data, the classiﬁca�on criteria are not met.
STOT - single exposure
Based on available data, the classiﬁca�on criteria are not met.
STOT - repeated exposure
Based on available data, the classiﬁca�on criteria are not met.
Aspira�on hazard
Based on available data, the classiﬁca�on criteria are not met.
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122B

54B

11B

55B

11.2. Informa�on on other hazards
11.2.1.
Endocrine disrupting properties
Endocrine disrup�ng proper�es
11.2.2.
Other information
Other adverse eﬀects

12.1. Toxicity
Ecotoxicity
124B

Unknown aqua�c toxicity

No informa�on available.

12.3. Bioaccumula�ve poten�al
Bioaccumula�on

No informa�on available.

12.4. Mobility in soil
Mobility in soil

No informa�on available.

126B

38B

127B

39B

Based on available data, the classiﬁca�on criteria are not met. Based on available data, theclassiﬁca�on criteria are not met.
Contains 0 % of components with unknown hazards to the aqua�c environment.

12.2. Persistence and degradability
Persistence and degradability
125B

37B

No informa�on available.

SECTION 12: Ecological informa�on

123B

36B

This product does not contain any known or suspected endocrine disruptors.

12.5. Results of PBT and vPvB assessment
PBT and vPvB assessment
The product does not contain any substance(s) classiﬁed as PBT or vPvB.
128B

40B

12.6. Endocrine disrup�ng proper�es
Endocrine disrup�ng
proper�es
129B

41B

12.7. Other adverse eﬀects
Other adverse eﬀects
130B

This product does not contain any known or suspected endocrine disruptors.

No informa�on available.

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SECTION 13: Disposal considera�ons
13.1. Waste treatment methods
Waste from residues/unused
products
Contaminated packaging
Waste codes / waste
designa�ons according to EWC
/ AVV
131B

132B

133B

13B

57B

Dispose of in accordance with local regula�ons. Dispose of waste in accordance withenvironmental legisla�on.
Do not reuse empty containers.
According to the European Waste Catalog, Waste Codes are not product speciﬁc, but applica�on
speciﬁc. Waste codes should be assigned by the user based on the applica�on for which the
product was used.

SECTION 14: Transport informa�on
IMDG
14.1
14.2
14.3
14.4
14.5
14.6

RID

ADR

IATA

Not regulated
UN number or ID number
UN proper shipping name
Transport hazard class(es)Packing group
Environmental hazards
Special Precau�ons for Users
Special Provisions

Not regulated
Not regulated
Not regulated
Not applicableNot applicable

14.7

Mari�me transport in bulk according
to IMO instruments

No informa�on available

14.1
14.2
14.3
14.4
14.5
14.6

UN numberUN proper shipping name
Transport hazard class(es)Packing group
Environmental hazards
Special Precau�ons for Users
Special Provisions

14.1
14.2
14.3
14.4
14.5
14.6

UN number or ID number
UN proper shipping name
Transport hazard class(es)Packing group
Environmental hazards
Special Precau�ons for Users
Special Provisions

14.1
14.2
14.3
14.4
14.5
14.6

UN number or ID number
UN proper shipping name
Transport hazard class(es)Packing group
Environmental hazards
Special Precau�ons for Users
Special Provisions
Note:

None

Not regulated
Not regulated
Not regulated
Not regulated
Not applicableNot applicableNone
Not regulated
Not regulated
Not regulated
Not regulated
Not applicableNot applicableNone
Not regulated
Not regulated
Not regulated
Not regulated
Not applicableNot applicable
None
None

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SECTION 15: Regulatory informa�on
15.1. Safety, health and environmental regula�ons/legisla�on speciﬁc for the substance or mixtureNa�onal regula�ons
Germany
Water hazard class (WGK)
non-hazardous to water (nwg)
134B

European Union
Take note of Direc�ve 98/24/EC on the protec�on of the health and safety of workers from the risks related to chemical agents at
work.
Authoriza�ons and/or restric�ons on use:
This product does not contain substances subject to authoriza�on (Regula�on (EC) No. 1907/2006 (REACH), Annex XIV) This productdoes not contain substances subject to restric�on (Regula�on (EC) No. 1907/2006 (REACH), Annex XVII)Persistent Organic Pollutants
Not applicable
Ozone-deple�ng substances (ODS) regula�on (EC) 1005/2009
Not applicable
Interna�onal Inventories
Contact supplier for inventory compliance status
42B

15.2. Chemical safety assessment
Chemical Safety Report
135B

15B

No informa�on available

SECTION 16: Other informa�on

Key or legend to abbrevia�ons and acronyms used in the safety data sheet
Legend
ATE: Acute Toxicity Es�mate
SVHC: Substances of Very High Concern for Authoriza�on:
PBT: Persistent, Bioaccumula�ve, and Toxic (PBT) Substances
vPvB: Very Persistent and very Bioaccumula�ve (vPvB) Substances
Legend Sec�on 8: Exposure controls/personal protec�on
TWA
TWA (�me-weighted average)
Ceiling
Maximum limit value
SCBA
Self-contained breathing apparatus
Classiﬁca�on procedure
Classiﬁca�on according to Regula�on (EC) No. 1272/2008 [CLP]
Acute oral toxicity
Acute dermal toxicity
Acute inhala�on toxicity - gas
Acute inhala�on toxicity - vapor
Acute inhala�on toxicity - dust/mist
Skin corrosion/irrita�on
Serious eye damage/eye irrita�on
Respiratory sensi�za�on
Skin sensi�za�on
Mutagenicity
Carcinogenicity
Reproduc�ve toxicity
SDS – RNA Sensi�vity Panels (CLP)-EN Rev. A | December 2023

STEL*

STEL (Short Term Exposure Limit)
Skin designa�on

Method Used
Calcula�on method
Calcula�on method
Calcula�on method
Calcula�on method
Calcula�on method
Calcula�on method
Calcula�on method
Calcula�on method
Calcula�on method
Calcula�on method
On basis of test data
Calcula�on method
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SECTION 16: Other informa�on

STOT - single exposure
STOT - repeated exposure
Acute aqua�c toxicity
Chronic aqua�c toxicity
Aspira�on hazard
Ozone

Calcula�on method
Calcula�on method
Calcula�on method
Calcula�on method
Calcula�on method
Calcula�on method

Key literature references and sources for data used to compile the SDS
Agency for Toxic Substances and Disease Registry (ATSDR)
U.S. Environmental Protec�on Agency ChemView Database
European Food Safety Authority (EFSA)
European Chemicals Agency (ECHA) Commitee for Risk Assessment (ECHA_RAC)
European Chemicals Agency (ECHA) (ECHA_API)
EPA (Environmental Protec�on Agency)
Acute Exposure Guideline Level(s) (AEGL(s))
U.S. Environmental Protec�on Agency Federal Insec�cide, Fungicide, and Roden�cide Act
U.S. Environmental Protec�on Agency High Produc�on Volume Chemicals
Food Research Journal
Hazardous Substance Database
Interna�onal Uniform Chemical Informa�on Database (IUCLID)
Japan GHS Classiﬁca�onAustralia Na�onal Industrial Chemicals No�ﬁca�on and Assessment Scheme (NICNAS)
NIOSH (Na�onal Ins�tute for Occupa�onal Safety and Health)Na�onal Library of Medicine's ChemID Plus (NLM CIP)
Na�onal Library of Medicine’s PubMed database (NLM PUBMED)
United States of America Na�onal Toxicology Program (NTP)New Zealand's Chemical Classiﬁca�on and Informa�on Database (CCID)
Organiza�on for Economic Co-opera�on and Development Environment, Health, and Safety Publica�ons
Organiza�on for Economic Co-opera�on and Development High Produc�on Volume Chemicals Program
Organiza�on for Economic Co-opera�on and Development Screening Informa�on Data Set
World Health Organiza�on
Issuing Date
Revision Date
Revision Note

27-Apr-2023
27-Apr-2023
Ini�al Release.

This safety data sheet complies with the requirements of Commission Regula�on (EU) 2020/878 of 18 June 2020 amending Regula�on (EC)No. 1907/2006
Disclaimer
The informa�on provided in this Safety Data Sheet is correct to the best of our knowledge, informa�on and belief at the date of its
publica�on. The informa�on given is designed only as a guidance for safe handling, use, processing, storage, transporta�on, disposal andrelease and is not to be considered a warranty or quality speciﬁca�on. The informa�on relates only to the speciﬁc material designated andmay not be valid for such material used in combina�on with any other materials or in any process, unless speciﬁed in the text.
End of Safety Data SheetSDS – RNA Sensi�vity Panels (CLP)-EN Rev. A | December 2023

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