2009 年
1.Iwanami K, Matsumoto I, Yoshiga Y, Inoue A, Kondo Y, Yamamoto K, Tanaka Y, Minami R, Hayashi T,
Goto D, Ito S, Nishimura Y, Sumida T.:
Altered peptide ligands inhibit arthritis induced by glucose-6-phosphate isomerase peptide.
Arthritis Res Ther 11:R167,2009
2.Inoue A, Matsumoto I, Tanaka Y, Iwanami K, Kanamori A, Ochiai N, Goto D, Ito S, Sumida T.:
Tumor necrosis factor alpha-induced adipose-related protein expression in experimental arthritis and inrheumatoid arthritis.
Arthritis Res Ther 11(4):R118. Epub 2009 Aug 6
3.Segawa S, Goto D, Yoshiga Y, Hayashi T, Matsumoto I, Ito S, Sumida T.:
Low levels of soluble CD1d protein alters NKT cell function in patients with rheumatoid arthritis.
Int J Mol Med 24(4):481-486,2009
4. Kawaguchi Y, Nakamura Y, Matsumoto I, Nishimagi E, Kamatani N, Satoh T, Kuwana M, Sumida T, Hara
M.:
Muscarinic-3 acetylcholine receptor autoantibody in patients with systemic sclerosis: contribution to severe
gastrointestinal tract dysmotility.
Ann Rheum Dis 68:710-714,2009
5.Kondo Y, Ito S,Ohi Y, Satou H, Hiraoka T, Tsuboi H, Sugihara M, Hayashi T, Goto D, Matsumoto I,
Sumida T.:
Atypical Cogan's Syndrome with aortitis.
Intern Med 48:1093-1037,2009
6.Wakamatsu E, Matsumoto I, Yoshiga Y, Hayashi T, Goto D, Ito S, Sumida T.:
Altered peptide ligands regulate type II collagen-induced arthritis in mice.
Mod Rheumatol 19:366-371,2009
7.Suzuki T, Ito S, Handa S, Kose K, Okamoto Y, Minami M, Hayashi T, Goto D, Matsumoto I, Sumida T.:
A new low-field extremity magnetic resonance imaging and proposed compact MRI score: Evaluation of antitumor necrosis factor biologics on rheumatoid arthritis.
Mod Rheumatol 19:358-365,2009
8.Horikoshi M, Ito S, Ishikawa M, Umeda N, Kondo Y, Tsuboi H, Hayashi T, Goto D, Matsumoto I, Sumida
T.:
Efficacy of mizoribine pulse therapy in patients with rheumatoid arthritis who show reduced or insufficient
response to infliximab.
Mod Rheumatol 19:229-234, 2009
9.Kobayashi T, Murasawa A, Ito S, Yamamoto K, Komatsu Y, Abe A, Sumida T, Yoshie H.:
Cytokine gene polymorphisms associated with rheumatoid arthritis and periodontitis in Japanese adults.
J Periodontology 80:792-799,2009
10.Ito I, Kawasaki A, Ito S, Hayashi T, Goto D, Matsumoto I, Tsutsumi A, Geoffrey Hom, Robert R. Graham,
Takasaki Y, Hashimoto H, Ohashi J, Timothy W. Behrens, Sumida T, Tsuchiya N.:
Replication of the Association between C8orf13-BLK Region and Systemic Lupus Erythematosus in a
Japanese Population.
Arthritis Rheum 60(2):553-558,2009

11.Tsutsumi A, Kobayashi T, Ito S, Goto D, Matsumoto I, Yoshie H, Sumida T.:
Mannose binding lection gene polymorphisms and the severity of chronic periodontitis.
Jap J Clin Immunol 32:48-52,2009
12.Tanaka-Watanabe Y, Matsumoto I, Iwanami K, Inoue A, Goto D, Ito S, Tsutsumi A, Sumida T.:
B cell play crucial role as antigen presenting cells and collaborationg with inflammatory cytokines in glucose6-phoaphate isomerase-induced arthritis.
Clin Exp Immunol 155:285-294,2009

2008 年
1.Nakamura Y, Wakamatsu E, Matsumoto I, Tomiita M, Kohno Y, Mori M, Yokota S, Goto D, Ito S,
Tsutsumi A, Sumida T.:
High prevalence of autoantibodies to muscarinic-3 acetylcholine receptor in patients with juvenile-onset
Sjögren's syndrome.
Ann Rheum Dis 67(1):136-137,2008
2.Tatsumura M, Mishima H, Shiina I, Hara Y, Nishiura Y, Ishii T, Ochiai N, Ishii W, Sumida T.:
Femoral nerve palsy cuased by a huge iliopectineal synovitis extending to the iliac fossa in a rheumatoid
arthritis case.
Mod Rheumatol 18:81-85,2008
3.Kohno M, Tsutsumi A, Matsui H, Sugihara M, Suzuki T, Mamura M, Goto D, Matsumoto I, Ito S, SuguroT, Sumida T.:
Interleukin-17 gene expression in patients with rheumatoid arthritis.
Mod Rheumatol 18:15-22,2008
4.Iwanami K, Matsumoto I, Watanabe Y, Mihara M, Ohsugi Y, Mamura M, Goto D, Ito S, Tsutsumi A,
Kishimoto T, Sumida T.:
Crucial role of IL-6/IL-17 cytokine axis in the induction of arthritis by glucose-6-phosphate-isomerase.
Arthritis Rheum 58(3):754-763 ,2008
5.Ishii W, Ito S, Kondo Y, Tsuboi H, Mamura M, Goto D, Matsumoto I, Tsutsumi A, Sumida T, Okoshi Y,
Hasegawa Y, Kojima H, Sakashita S, Aita K, Noguchi M.:
Intravascular large B-cell lymphoma with acute abdomen as a presentingsymptom in a patient with systemic
lupus erythematosus.
J Clin Oncol 26(9):1553-5,2008
6.Matsui H, Tsutsumi A, Sugihara M, Suzuki T, Iwanami K, Kohno M, Goto D, Matsumoto I, Ito S, Sumida
T.:
Visfatin(pre-B cell colony-enhancing factor) gene expression in patients with rheumatoid arthritis.
Ann Rheum Dis 67(4):571-572,2008
7.Wang Y, Ito S, Chino Y, Iwanami K, Yasukochi T, Goto D, Matsumoto I, Hayashi T, Uchida K, Sumida T.:
Use of Laser Microdissection in the Analysis of Renal-infiltrating T cells in MRL/lpr Mice.
Mod Rheumatol 18:385-393,2008
8.Furuya T, Matsumoto I, Tsuchiya N, Hakoda M, Ichikawa N, Higami K, Nanke Y, Sumida T, Kamatani N,
Kotake S.:
Anti-glucose-6-phosphate isomerase, anti-cyclic citrullinated peptide antibodies and HLA-DRB1 genotypes inJapanese patients with early rheumatoid arthritis.

Clin Exp Rheumatol 26(5):918-921,2008
9.Matsumoto I, Zhang H, Yasukochi T, Iwanami K, Tanaka Y, Inoue A, Goto D, Ito S, Tsutsumi A, Sumida
T.:
Therapeutic effects of antibodies to TNF alpha and IL-6 and CTLA-4 Ig in mice with glucose-6-phosphate
isomerase-induced arthritis.
Arthritis Res Ther 10(3):R66,2008
10.Ishii W, Matsuda M, Shimojima Y, Itoh S, Sumida T, Ikeda S-I.:
Flow cytometric analysis of lymphocyte subpopulations and Th1/Th2 balance in patients with poly myositis
and dermatomyositiis.
Intern Med 47(18)1593-1599,2008
11.Yoshiga Y, Goto D, Segawa S, Ohnishi Y, Matsumoto I, Ito S, Tsutsumi A, Taniguchi M, Sumida T.:
Invariant NKT cells produce IL-17 through IL-23-dependent and -independent pathways with potential
modulation of Th17 response in collagen-induced arthritis
Int J Mol Med 22:369-374,2008
12. Kawasaki A, Ito I, Hikami K, Ohashi J, Hayashi T, Goto D, Matsumoto I, Ito S, Tsutsumi A, Koga M,
Arinami T, Robert R Graham, Geoffrey Hom, Takasaki Y, Hashimoto H, Timothy W Behrens, Sumida T,
Tsuchiya N.:
Role of STAT4 polymorphisms in systemic lupus erythematosus in a Japanese population: a case-control
association study of STAT1-STAT4 region.
Arthritis Res Ther 10:R113,2008
13. Suzuki T, Tsutsumi A, Suzuki E, Sugihara M, Muraki Y, Hayashi T, Chino Y, Goto D, Matsumoto I, Ito
S, Sumida T.:
Tristetraprolin(TTP) gene polymorphisms in patients with rheumatoid arthritis and healthy individuals.
Mod Rheumatol 18:472-479,2008
14.Iwanami K, Matsumoto I, Tanaka Y, Inoue A, Goto D, Ito S, Tsutsumi A, Sumida T.:
Arthritogenic T cell epitope in glucose-6-phosphate isomerase (GPI)-induced arthritis.
Arthritis Res Ther 10(6):R130,2008

2007 年
1.Sumida T, Wakamatsu E, Nakamura Y, Matsumoto I.:
Autoantibodies against muscarinic acetylcholine receptor in patients with Sjögren's syndrome.(review)
In Textbook of Autoantibodies Second Edition ed. by Y. Shoenfeld, M. E. Gershwin and P. L.
Meroni. Elsevier, 681-686, 2007
2.Wakamatsu E, Nakamura Y, Matsumoto I, Goto D, Ito S, Tsutsumi A, Sumida T.:
DNA microarray analysis of labial salivary gland of patients with Sjögren's syndrome.
Ann Rheum Dis 66:844-845,2007
3.Yamada H, Nakagawa Y, Wakamatsu E, Sumida T, Yamachika S, Nomura Y, Mishima K, Saito I.:
Efficacy prediction of cevimeline in patients with Sjögren's syndrome.
Clin Rheumatol 26:1320-1327,2007
4.Yamada H, Ishii W, Ito S, Iwanami K, Ogishima H, Suzuki T, Mamura M, Goto D, Matsumoto I, Tsutsumi
A, Sumida T.:

Sarcoid myositis with muscle weakness as a presenting symptom.
Mod Rheumatol 17:243-246, 2007
5. Matsuyama M, Suzuki T, Tsuboi H, Ito S, Mamura M, Goto D, Matsumoto I, Tsutsumi A, Sumida T.:
Anti-interleukin-6 receptor antibody (tocilizumab) treatment of multicentric Castleman's disease.
Intern Med 46, 771-774, 2007
6.Kobayashi T, Ito S, Yasuda K, Kuroda T, Yamamoto K, Sugita N, Tai H, Narita I, Gejyo F, Yoshie H.:
The Combined Genotypes of Stimulatory and Inhibitory Fcγ Receptor Associated with Systemic Lupus
Erythematosus and Periodontitis in Japanese.
J Periodontol 78(3) 467-474, 2007
7.Sugihara M, Tsutsumi A, Suzuki E, Wakamatsu E, Suzuki T, Ogishima H, Hayashi T, Chino Y, Ishii W,
Mamura M, Goto D, Matsumoto I, Ito S, Sumida T.:
Effects of infliximab therapy on gene expression levels of tumor necrosis factor alpha, tristetraprolin, T cell
intracellular antigen 1, and Hu antigen R in patients with rheumatoid arthritis.
Arthritis Rheum 56(7):2160-2169,2007
8.Takana Y, Yamamoto K, Takeuchi T, Nishimoto N, Miyasaka N, Sumida T, Shima Y, Takada K,
Matsumoto I, Saito K, Koike T.:
A multi-center phase I/II trial of rituximab for refractory systemic lupus erythematosus.
Mod Rheumatol 33(2):173-81,2011
9.Enami T, Suzuki T, Ito S, Yoshimi A, Sugihara M, Mamura M, Hayashi T, Goto D, Matsumoto I, Tsutsumi
A, Sumida T.:
Successful treatment of refractory thrombotic thrombodytopenic purpura with cyclosporine andcorticosteroids in a patient with systemic lupus erythematosus and antibodies to ADAMTS13.
Intern Med 46:1033-1037, 2007
10.Hayashi T, Matsumoto I, Yasukochi T, Mamura M, Goto D, Ito S, Tsutsumi A, Sumida T.:
Biased usage of synovial immunoglobulin heavy chain variable region 4 by the anti-glucose-6-phosphate
isomerase antibody in patients with rheumatoid arthritis.
Int J Mol Med 20(2):247-253,2007
11.Kobayashi T, Ito S, Kuroda T, Yamamoto K, Sugita N, Narita I, Sumida T, Gejyo F, Yoshie H.: The
Interleukin-1 and Fcg Receptor Gene Polymorphisms in Japanese Patients with Rheumatoid Arthritis andPeriodontitis
J Periodont 78(12):2311-2318,2007
12.Kuroda T, Hirose S, Tanabe N, Sato H, Nakatsue T, Ajiro J, Wada Y, Murakami S, Hasegawa H, Ito S,
Sakatsume M, Nakano M, Gejyo F.:
Mizoribine therapy for patients with lupus nephritis: the association between peak mizoribine concentrationand clinical efficacy.
Mod Rheumatol 17:206-212,2007
13.Nakayamada S, Saito K, Umehara H, Ogawa N, Sumida T, Ito S, Minota S, Nara H, Kondo H, Okada J,
Mimori T, Yoshifuji H, Sano H, Hashimoto N, Sugai S, Tanaka Y.:
Efficacy and Safety of Mizoribine for the Treatment of Sjögren’s Syndrome - A Multicenter Open-label
Clinical Trial.
Mod Rheumatol 17(6):464-469,2007

2006 年
1.Naito Y, Matsumoto I, Wakamatsu E, Goto D, Ito S, Tsutsumi A, Sumida T.:
Altered peptide ligants regulate muscarinic acetylcholine receptor reactive T cells of patients with Sjögren's
Syndrome.
Ann Rheum Dis 65:269-271,2006
2.Chino Y, Murata H, Goto D, Matsumoto I, Tsutsumi A, Sakamoto T, Ohtsuka M, Sekisawa K, Ito S,
Sumida T.:
T cell receptor BV gene repertoire in lymphocytes from bronchoalveolar lavage fjuid of polymyositis/
dermatomyositis patients with interstitial pneumonitis. Int.
J Mol Med 17:101-109,2006
3.Yoshioka H, Ito S, Handa S, Tomiha S, Kose K, Haishi T, Tsutsumi A,Sumida T.:
Low-fied compact magnetic resonance imaging system for the hand and wrist in rheumatoid arthritis.
JMRI 23:370-376,2006
4.Suzuki E, Tsutsumi A, Goto D, Matsumoto I, Ito S, Otsu M, Onodera M, Takahashi S, Sato Y, Sumida T.:
Gene transduction of tristetraprolin or its active domain reduces TNF-α production in Jurkat T cells.
Int J Mol Med.17(5)801-809,2006
5. Ito S, Sugihara M, Suzuki T, Mamura M, Goto D, Matsumoto I, Tsutsumi A, Sumida T.:
Diagnosis of Chlamydia-induced reactive arthritis.
Intern Med(letter)45(1)37-37,2006
6.Kori Y., Matsumoto I., Hua Zhang., Yasukochi T., Hayashi T., Iwanami K., Goto D., Ito S., Tsutsumi A.,
Sumida T.:
Characterization of Th1/Th2 type, glucose-6-phosphate isomerase reactive T cells in the generation ofrheumatoid arthritis.
Ann. Rheum. Dis 65:968-969,2006
7.Kai H, Shibuya K, Wang Y, Kameta H, Kameyama T, Tahara-Hanaoka S, Miyamoto A, Honda S,
Matsumoto I, Koyama A, Sumida T, Shibuya A.:
Critical role of M.tuberculosis for dendritic cell maturation to induce collagen-induced arthritis in H-2b
background of C57BL/6 mice
Immunology 118:233-239,2006
8.Ito S, Gross WL, Reinhold-Keller E, Gause A, Aries P, Ru¨ther W, Mansoury T, Awad R, Badawy S,
Murasawa A, Gejyo F.:
Rheumatology in Japan, Germany, and Egypt: Comparison of Medical Practices.
Acta Med Biol 54(2):51-58,2006
9.Suzuki E, Tsutsumi A, Sugihara M, Mamura M, Goto D, Matsumoto I, Ito S, Ikeda K, Ochiai N, Sato Y,
Sumida T.:
Expression of TNF-α, tristetraprolin, T-cell intracellular antigen-1 and Hu antigen R genes in synobium ofpatients with rheumatoid arthritis.
Int.J.Mol.Med. 18:273-278,2006
10.Tsutsumi A, Hayashi T, Chino Y, Goto D, Matsumoto I, Ito S, Sumida T.:
Significnace of antiprothrombin antibodies in patients with systemic lupus erythematosus: clinical evaluationof the antiprothrombin assay and the antiphosphatidylserine/prothrombin assay, and comparison with otherphospholipids antibody assays.

Mod Rheumatol.16:158-164,2006
11.Wakamatsu E, Matsumoto I, Yasukochi T, Naito Y, Goto D, Mamura M, Ito S, Tsutsumi A, Sumida T.:
Overexpression of phosphorylated stat1-α in labial salivary glands of patients with Sjögren's Syndrome.
Arthritis Rheum 54(11):3476-3484,2006
12.Ohnishi Y, Tsutsumi A, Matsumoto I, Goto D, Ito S, Kuwana M, Uemura Y, Nishimura Y, Sumida T.:
Altered peptide ligands control type 2collagen-reactive T cells from RA patients.
Mod Rheumatol 16:226-228,2006
13. Kurata M., Nozue M., Seino K.-I., Murata H., Sumida T., and Fukao K.:
Indications for surgery in intestinal Behcet's disease.
Hepatogastroenterology 53(67):60-3,2006

2005 年
1.Takahashi R., Tsutsumi A., Ohtani K., Muraki Y., Goto D., Matsumoto I., Wakamiya N., and Sumida T.:
Association of mannose-binding lection(MBL) gene polymorphism and serum MBL concentration withcharacteristics and progression of systemic lupus erythematosus.
Ann Rheum Dis 64(2):311-314,2005
2.Ota M., Mizukami K., Hayashi T., Sumida T., Asada T.:
Brain magnetic resonance imaging and single photon emission computerized tomography findings in a case of
relapsing polychondritis showing cognitive impairment and personality changes.
Prog Neuropsychopharmacol Bio Psychiatry.29(2):347-349,2005
3.Naito Y., Matsumoto I., Wakamatsu E., Goto D., Sugiyama T., Matsumura R., Ito S.,Tsutsumi A., SumidaT.:Muscariinic acetylcholine recepter auto antibodies in patients with Sjögren's Syndrome.
Ann Rheum Dis.64（3):510-511,2005
4.Tomoo T., Tsutsumi A., Yasukochi T., Ikeda T., Ochiai N., Ozawa K., Shibanaka Y., Ito S., Matsumoto I.,
Goto D., Sumida T.:
Analysis of abnormally expressed genes in synovium from patients with rheumatoid arthritis using a column
gel electrophoresis-coupled subtractive hybridization technique.
Int J Mol Med 15(3):453-457,2005
5.Suzuki T., Muraki Y., Yasukochi T., Hua Zhang., Kori Y., Wakamatsu E., Hayashi T., Goto D., Ito S.,
Tsutsumi A., Sumichika H., Sumida T., Matsumoto I.:
Immunoglobulin G from anti-glucose-6-phosphate isomerase antibodies positive patient with rheumatoid
arthritis induces synovitis in cynomolgus monkeys
Autoimmunity Reviews 4:475-478,2005
6.Hayashi T, Matsumoto I, Muraki Y, Takahashi R, Chino Y, Goto D, Ito S, Tsutsumi A, Sumida T.:
Clinical Characteristics of Anti-Glucose-6-Phosphate Isomerase Antibodies positive Japanese Patients with
Rheumatoid Arthritis.
Mod Rheumatol 15:258-263,2005
7.Matsumoto I, Muraki Y, Yasukochi T, Hua Zhang, Kori Y, Hayashi T, Goto D, Ito S, Tsutsumi A, Ikeda K,
Sumichika H, Sumida T.:
The exploration of joint-specific immunoreactions on immunoglobulins G of anti-glucose-6-phosphate
isomerase antibody-positive patients with rheumatoid arthritis.
Int J Mol Med 16(5):793-800,2005

8.Matsumoto I, Hua Zhang, Muraki Y, Hayashi T, Yasukochi T, Kori Y, Goto D, Ito S, Tsutsumi A, SumidaT.:A functional variant of Fcy receptor IIIA is associated with rheumatoid arthritis in anti-glucose-6-phosphate
isomerase antibodies-positive individuals.
Arthritis Res Ther 7:1183-1188,2005
9.Takahashi R, Tsutsumi A, Ohtani K, Wakamiya N, Sumida T.:
Mannose-binding lectin variant alleles are not a risk factor for arterial thrombosis in Japanese patients withsystemic lupus erythematosus.
Mod.Rheumatol (letter) 15:459-460,2005
10.Miyahara S, Ito S, Soeda A, Chino Y, Hayashi T, Takahashi R, Goto D, Matsumoto I, Tsutsumi A, SumidaT.:
Two cases of systemic lupus erythematosus complicated with colonic ulcers.
Intern Med. 44(12)1298-1306,2005
11.Ohnishi Y, Tsutsumi A, Goto D, Ito S, Matsumoto I, Taniguchi M,Sumida T.:
TCRVa14+NKT cells function as effector T cells in collagen-induced arthritis mice
Clin Exp Immunol 141:47-53,2005
12.Tsutsumi A, Takahashi R, Sumida T.:
Mannose binding lectin:genetics and autoimmune disease.
Autoimmunity Reviews 4:364-372,2005
13.Sumida T.:
Comments to the editor concerning paper by Naito,Y et al.
Ann Rheum Dis 2005
14.Kitagawa M, Goto D, Mamura M, Matsumoto I, Ito S, Tsutsumi A, Sumida T.:
Inhibitory peptides of CD40/CD154 interaction.
Mod Rheumatol 15:423-426,2005
15.Suzuki E, Hayashi T, Ito S, Miyazaki K, Yamazaki H, Machino T, Takahashi R, Chino Y, Goto D,
Matsumoto I, Tsutsumi A, Sato Y, Sumida T.:
A case of pulmonary hypertension associated with systemic lupus erythematosus without antiribonucleoprotein antibodies
ACTA MEDICA et BIOLOGICIA 53(3)87-93,2005
2004 年
1.Tsutsumi A., Adachi Y., Murata H., Kojo S., Shibuya K., Nakamura H., and Sumida T.:
G0S24, a gene that regulates TNFa production,is highly expressed in synovial tissue from patients withrheumatoid arthritis.
J Rheumatol 31(6):1044-9,2004
2.Takahashi R., Tsutsumi A., Ohtani K., Goto D., Matsumoto I., Ito S., Wakamiya N.,and Sumida T.:
Anti-mannose binding lectin antibodies in sera of Japanese patients with systemic lupus erythematosus.
Clin Exp Immunol 136(3):585-590,2004
3.Muraki Y., Tsutsumi A., Takahashi R., Suzuki E., Hayashi T., Chino Y., Goto D., Matsumoto I.,Murata H.,
Noguchi E., and Sumida T.:
Polymorphisms of IL-1β Gene in Japanese Patients with Sjögren’s Syndrome and Systemic Lupus
Erythematosus.
J Rheumatol 31:720-725,2004

4.Muraki Y., Matsumoto I., Chino Y., Hayashi T., Suzuki E., Goto D., Ito S., Murata H., Tsutsumi A., Sumida
T.:
Glucose-6-phosphate isomerase variants play a key role in the generation of anti-GPI antibodies.Possible
mechanism of autoantibody production.
Biochem Biophys Research Commun 323(2):518-522,2004
5. Asatsuma M., Ito S., Watanabe M., Takeishi H., Momura S., Wada Y., Nakano M., Gejyo F., Igarashi A.:
Increase in the ratio of matrix metalloprotease-9 to tissue inhibitor of metalloproteinase-1 in saliva frompatients with Primary Sjögren’s syndrome.
Clin Chim Acta 345:99-104, 2004
6.Kato T., Asahara H., Kurokawa MS., Fujisawa K., Hasunuma T., Inoue H., Tsuda M., Takahashi S.,
Motokawa S., Sumida T., Nishioka K.:
HTLV-I env protein acts as a major antigen in patients with HTLV-I-associated arthropathy.
Clin Rheumatol 23(5)400-9,2004
7.Kuroda T., Ohbayashi H., Murakami S., Ito S., Sakatsume M., Ueno M., Nishi S., Nakano M., Gejyo F.:
A case of Takayasu arteritis complicated with glomerulonephropathy mimicking membranoproliferative
glomerulonephritis
Clin Rheumatol 23:536-540,2004
8.Ito S., Sumida T.:
Interstitial Lung Disease Associated with Leflunomide.
Intern Med 43(12):1103-1104,2004
9.Iguchi S., Kasai A., Kishimoto H., Suzuki K., Ito S., Ogawa Y., Nishi S., Gejyo F., Ohno Y.:
Thrombosis in inferior vena cava (IVC) due to intra-cyst hemorrhage into a hepatic local cyst with autosomal
dominant polycystic kidney disease(ADPKD).
Intern Med 43:209-212,2004
10.Wada Y., Murayama S., Hirose S., In H., Kuroda T., Ito S., Nakano M., Gejyo F.:
A case of pneumatosis cystoides intestinalis in a patient with polymyositis and interstitial pneumonia.
Mod Rheumatol 14:260-263,2004
11.Alchi B., Sekiguchi T., Ogino S., Nishi S., Ito S., Mori H., Ueno M., Gejyo F.:
A 70-year-old man with weight loss, dry mouth and renal insufficiency.
Nephrol Dial Transplant 19:2661-2664,2004
12.Kanazawa M., Wada Y., Ohno T., In H., Yahata K., Izumi J., Tanaka H., Ito S., Ueno M., Nakano M.,
Gejyo F.:
Mixed connective tissue disease associated with antineutrophil cytoplasmic antibodies against proteinase-3
and systemic atherosclerosis : a case report.
Clin Rheumatol 23:456-459,2004
13.Yoko W., Ito S., Mitsuhiro U., Nakano M., Arakawa M., Gejyo F.:
Renal outcome and predictors of clinical renal involvement in patients with silent nephritis.
Nephron 98:105-111,2004

2003 年
1 . Ohnishi Y., Tsutsumi A., Sakamaki T., and Sumida T.:
T cell epitopes of type II collangen in HLA-DRB1*0101 or DRB1*0405-positive Japanese patients withrheumatoid arthritis.
International Journal of Molecular Medicine 11:331-335,2003

2 .Ohnishi Y., Tsutsumi A., and Sumida T.:
Antibodies to type II collagen and their association with HLA DR1 alleles in Japanese patients withrheumatoid arthritis.
Mod. Rheumatol. 13:69-72,2003
3.Adachi Y., Tsutsumi A., Murata H., Takemura H., Chino Y., Takahashi R., Ebitsuka T., and Sumida T.:
Behcet's disease accompanied by myelodysplastic syndrome with trisomy 8: Two case reports and review of
15 Japanese cases.
Mod Rheumatol 13:90-94, 2003
4 .Matsumoto I., David M Lee., Raphaela Goldbach-Mansky., Sumida T., Carol A Hitchon., Peter H. Schur.,
Ron J Anderson., Jonathan S Coblyn., Michael E Weinblatt., Michael Brenner., Bernard Duclos., Jean-Louis
Pasquali., Hani El-Gabalawy., Diane Mathis. , and Christophe Benoist.:
Low prevalence of antibodies to glucose-6-phosphate isomerase in patients with rheumatoid arthritis and aspectrum of other chronic autoimmune disorders
Arthritis and Rheumatism 48:944-954, 2003
5.Yoshida K., Tsutsumi A., Ohnishi Y., Akimoto T., Murata H., and Sumida T.:
T cell epitopes of prothrombin in patients with antiphospholipid syndrome.
Ann Rheum Dis. 62:1-2,2003
6.Tsutsumi A., Ikegami H., Takahashi R., Murata H., Goto D., Matsumoto I., Fujisawa T., and Sumida T.:
Mannose binding lectin gene polymorphism in patients with type I diabetes.
Human Immunology. 64:621-624, 2003
7. Kojo S., Tsutsumi A., Goto D., and Sumida T.:
Low expression levels of soluble CD1d gene in patients with rheumatoid arthritis.
The journal of Rheumatology 30:2524-2528,2003
8. Murata H., Adachi Y., Ebitsuka T., Chino Y., Takahashi R., Hayashi T., Goto D., Matsumoto I., Tsutsumi
A., Akaza H., and Sumida T.:
Reiter's syndrome following intravesical Bacille bilie de Calmette-Guerin treatment for superficial bladdercarcinoma. Report of six cases.
Mod Rheumatol. 14:82-86,2004
9.Sumida T.:
Immunological abnormality and regulation in patients with Sjögren's syndrome.
Arthritis Res Ther 5(Suppl 3):159,2003
10.Shibuya K., Shirakawa J., Kameyama T., Honda S.-1.,Tahara-Hanaoka S., Miyamoto A., Onodera M.,
Sumida T.,Nakauchi H., Miyoshi H., and Shibuya A.:
CD226(DNAM-1) is involved in LFA-1 costimlatory signal for naive T cell differentiation and proliferation.
J Exp Med 198:1829-1839,2003
11.Arakaki R., Ishimaru N., Saito I., Kobayashi M., Yasui N., Sumida T., and Hayashi Y.:
Development of Autoimmune Exocrinopathy Resembling Sjören's Syndrome in Adoptively Transferred Mice
With Autoreactive CD4+T Cells.
Arthritis and Rheumatism 48:3603-3609,2003
12.Ito S., Kuriyama H., Iino N., Iguchi S., Shimada H., Ueno M., Narita I., Nakano M., Nishi S., Karasawa R.,
Gejyo F.:
Patient with diffuse mesangial and endocapillary proliferative glomerulonephritis with hypocomplementemia
and elevated anti-streptolysin O treated with prednisolone, angiotensin-converting enzyme inhibitor, andangiotensin II receptor antagonist.
Clin Exp Nephrol 7:290-295, 2003

2002 年
1.Yasuda S., Tsutsumi A., Atsumi T., Maria L.Bertolaccini., Ichikawa K., Munther A. Khamashta., Graham
R.V. Hughes., and Koike T.:
Gene Polymorphisms of Tissue Plasminogen Activator and Plasminogen Activator Inhibitor-1 in Patients with
Antiphospholipid Antibodies.
J Rheumatol 29(6):1192-1197,2002
2.Matsumoto I., Maccioni M., David M. Lee., Madelon Maurice., Barry Simmons., Michael Brenner., Diane
Mathis., and Christophe Benoist.:
How antibodies to a ubiquitous cytoplasmic enzyme may provoke joint-specific autoimmune disease.
Nature Immunol 3(4):1-7,2002
3. Shimizudani N., Murata H., Keino H., Kojo S., Nakamura H., Morishima Y., Sakamoto T., Ohtsuka M.,
Sekizawa K., Sumida M., Sumida T., and Matsuoka T.:
Conserved CDR 3 Region of T Cell Receptor BV Gene in Lymphocytes from Bronchoalveolar Lavage Fluidof Patients with Idiopathic Pulmonary Fibrosis.
Clin Exp Immunol 129 (1):140-149,2002
4. Matsumoto I., and Sumida T.:
B cells and Immunoglobulins dependent mechanisms in rheumatoid arthritis.
Ther Apher 6(4):317,2002
5. Tsutsumi A., Ebitsuka T., Murata H., Takemura H., and Sumida T.:
A case of HLA B27 positive coxitis diagnosed 15 years after onset.
Mod Rheumatol. 12:349-353 ,2002
6.Yagi K., Furuhashi M., Aoki H., Goto D., Kuwano H., Sugamura K., Miyazono K., and Kato M.:
c-myc is a downstream target of the Smad pathway.
J Biol Chem 277(1):854-861,2002
7.Murata H., Matsumura R., Koyama A., Sugiyama T., Sueishi M., Shibuya K., Tsutsumi A., and Sumida T.:
T Cell Receptor of T Cells in the Kidneys of Patients with Lupus Nephritis.
Arthritis Rheum 46(8):2141-2147,2002
8.Yasukochi T., Ozawa K., Sato M., Sumida T., and Shibanaka, Y.:
Evaluation of the improvement of IGC technique.
Nucleic Acids Res, Suppl. 2:199-200, 2002
9. Kurata M., Nozue M., Seino K.-I., Murata H., Sumida T., and Fukao K.：
Indications for surgery in intestinal Behcet's disease.
Hepatogastroenterology 53(67):60-63,206
10.Matsumoto I., Sumida T.: B Cells and Immunoglobulins Dependent Mechanisms in Rheumatoid Arthritis:
A Possible Rationale of the Extracorporeal Immunomodulation for Rheumatoid Arthritis.
Therapeutic Apheresis 6:317-319,2002

2001 年
1. Oishi, Y., Sumida, T., Sakamoto, A., Kita, Y., Kurasawa, K., Nawata, Y., Takabayashi, K., Takahashi, H.,
Yoshida, S., Taniguchi, M., Saito, S., and Iwamoto, I.:
Selective reduction and recovery of invariant Va24JaQ T cell receptor T cells in correlation with diseaseactivity in patients with systemic lupus erythematosus.
J Rheumatol. 28:275-283, 2001.

2. Akimoto, T., Akama, T., Saito, M., Kono, i., and Sumida, T.:
Anti-prothorombin autoantibodies in gestational toxicosis and abortion.
Am J Med 110:188-191, 2001
3. Keino, H., Takeuchi, M., Kojo, S., Suzuki, J., Sakai, J., Nishioka, K., Sumida, T., and Usui, M.:
Identification of regulatory T cells among in vivo expanded ocular T cells in mice with experimental
autoimmune uveoretinitis.
Clin Exp Immunol 124:1-8, 2001
4. Kojo, S., Adachi, Y., Keino, H., Taniguchi, M., and Sumida, T.:
Dysfunction of TCR AV24AJ18+BV11+ double negative regulatory NKT cells in autoimmune diseases.
Arthritis Rheum. 44(5):1127-1138, 2001
5. Tsutsumi, A., Atsumi, T., Yamada, H., Hirayama-Kato, E., Ichikawa, K., Fujimoto, S., and Koike, T.:
Anti-phosphatidylserine/prothorombin antibodies are not frequently in patients with unexplained recurrent
miscarriages.
Am J Reprod Immunol 46(3):242-244, 2001
6. Tsutsumi, A., Sasaki, K., Wakamiya, N., Ichikawa, K., Atsumi, T., Ohtani, K., Suzuki, Y., Koike, T., andSumida, T.:
Mannose binding lectin gene: Polymorphisms in japanese patients with systemic lupus erythematosus,
rheumatoid arthritis and Sjögren's syndrome.
Genes Immun 2(2):99-104, 2001
7. Kitagawa, M., Suzuki, H., Adachi, Y., Nakamura H., Yoshino, S., and Sumida, T.:Interferon-gamma enhances interleukin-12 production in rheumatoid synovial cells via CD40-CD154
dependent and independent pathways.
J Rheumatol 28(8):1764-1771.2001
8. Shimizudani, N., Murata, H., Kojo, S., Adachi, Y., Keino, H., Tsuchida, F., Sumida, M., Kawamata, M.,
Sumida, T., Matsuoka, K.:
Analysis of T cell receptor Vbeta gene expression and clonality in bronchoalveolar fluid lymphocytes from apatient with chronic eosinophilic pneumonitis.
Lung 179:31-41.2001
9. Murata, H., and Sumida, T. Quantitative analysis of fetal michrochimerism in Japanese women withsystemic sclerosis.
Mod Rheumatol 11:259-260.2001
10. Nishio, M., Oda, A., Koizumi, K., Satoh, I., Sato, Y., Endoh, T., Tsutsumi, A., Fujihara, M., Ikebuchi, K.,
Ikdeda, H., Koike, T., and Sawada, K.:
Stem cell factor prevents Fas-mediated apoptosis of human erythroid precursor cells with Src-family kinasedependency.
Exp Hematol 29:19-29, 2001
11. Takahashi, R., Shimazak, Y., and Endoh, M.:
Influence of acidosis on PIE of UD-CG 212 CI in dog heart.
J Pharmacol Exp Ther 298(3):1060-1066.2001

2000 年
1. Wang, M., Keino, H., Matsumoto, I., Kurokawa, M., Kato, T., Nishioka, K., and Sumida, T.:A single cell analysis of Fas-ligand positive T cells in rheumatoid synovium.
J Rheumatol 27:311-318,2000

2. Enomoto, M., Takemura, H., Suzuki, M., Yuhara, T., Akama, T., Yamane, K., Sumida, T.:
Palmar Fasciitis and polyarthritis associated with gastric carcinoma: a paraneoplastic syndrome. (Case report)
Int Medicine 39(9):754-757,2000
3. Yuhara, T., Takemura, H., Akama, T., Yamane, K., and Sumida, T.:
The relationship between serum immunoglobulin and pulmonary involvement in systemic sclerosis.
J Rheumatol 27:1207-1214,2000
4. Suzuki, M., Takemura, H., Suzuki, H., and Sumida, T.:
Light chain determines the fine specificity of anti-dsDNA IgG autoantibodies obtained by a phage-display
method.
Biochem Biophys Research Commun 271:240-243, 2000.
5. Keino, H., Sakai, J.-I., Nishioka, K., Sumida, T., and Usui, M.:
Clonally accumulating ocular T cells in patient with Behcet's disease.
Am J Ophthal 130:243-245, 2000
6. Tsutsumi, A., Ichikawa, K., Matsuura, E., Sawada, KI., Koike, T.:
Heterogeneous behavior of anti-beta2-glycoprotein I antibodies on various commercially available enzyme
immunoassay plates coated with beta2-glycoprotein I.
J Rheumatol 27:391-369, 2000
7. Matsuura, E., Inagaki, J., Kasahara, H., Yamamoto, D., Atsumi, T., Kobayashi, K., Kaihara, K., Zhao, D.,
Ichikawa, K., Tsutsumi, A., Yasuda, T., Triplett, DA., Koike, T.:
Proteolytic cleavage of beta(2)-glycoprotein I: reduction of antigenicity and the structural relationship.
Int Immunol 12:1183-1192, 2000
8. Yin, W., Hasunuma, T., Kobata, T., Sumida, T., Nishioka, K.:
Synovial hyperplasia in HTLV-1 associated arthropathy is induced by tumor necrosis factor-alpha producedby HTLV-1 infected CD68+ cells.
J Rheumatol 27:874-881, 2000
9. Yuhara, T.,Takemura, H., Akama, T., Yamane, K., Sumida T.:
Necrotizing fasciitis caused by streptococcus pneumoniae in mixed connective tissue disease.
Mod Rheumatol 10:180-182,2000
10. Kojo, S., Adachi, Y., Tsutsumi, A., and Sumida, T.:
Alternative splicing forms of human CD1D gene in mononuclear cells. Biochem. Biophys.
Research Commun 276:107-111, 2000
11. Sumida, T.:T cell and autoantigens in Sjögren's syndrome.(review)
Modern Rheumatol 10:193-198, 2000
12. Okamoto, K., Kobayashi, T., Kobata, T., Hasunuma, T., Kato, K., Sumida, T., and Nishioka, K.:
Fas-associated death domain protein is a Fas-mediated apoptosis modulator in synoviocytes.
Rheumatology 39: 471-480, 2000
13. Morimoto, S., Hashimoto, H., Yamanaka, K., Tokano, Y., Nishimura, Y., Sawada, S., Kamatani, N.,
Sumida, T., Yoshizaki, K., Nakasawa, K., and Miyasaka, N.:
The multicenter cooperative study of HLA class II alleles in Japanese patients with systemic lupus
erythematosus.
Modern Rheumatol 10:235-239, 2000
14. Shibuya A., Sakamoto N., Shimizu Y., Shibuya K., Osawa M., Hiroyama T., Eyre H. J., Sutherland G. R.,
Endo Y., Fujita T., Miyabayashi T., Sakano S., Tsuji T., Nakayama E., Phillips J. H., Lanier L. L., andNakauchi H.:
Fca/m receptor mediates endocytosis of IgM-coated microbes.
Nature Immunol 1:441-446, 2000

1999 年
1. Akimoto, T., Akama, T., Kono, I., Yamane, K., and Sumida, T.:
Detergent and antigen fragility affect the ELISA for measurement of anti-prothrombin autoanticodies.
J Rheumatol 26: 580-587, 1999
2. Maeda, T., Keino, H., Asahara, H., Taniguchi, M., Nishioka, K., and Sumida, T.:
Decreased TCR AV24AJ18+ double negative T cells in rheumatoid synovium.
Br J Rheumatol 38:186-188, 1999
3. Kobayashi, T., Okamoto, K., Kobata, T., Hasunuma, T., Sumida, T., and Nishioka, K.:
TNF_ regulates Fas-mediated apoptosis signaling pathway in synovial cells.
Arthritis Rheum 42:519-526, 1999
4. Uehara, R., Fujisawa, K., Kezuka, T., Sakai, J.-I., Nishioka, K, Sumida, T., and Usui, M.:
Conserved TCR CDR3 region of infiltrating T cells in experimental autoimmune uveoritinitis.
Ophth Research 31:249-255, 1999
5. Sumida, T.:
Sjögren's syndrome.
Int Medicine 38:165-168,1999
6. Saitoh, I., Haruta, K., Shimura, M., Inoue, H., Sakurai, H., Yamada, K., Ishimaru, N., Higashiyama, H.,
Sumida, T., Ishida, H., Suda, T., Noda,T., Hayashi, Y., and Tsubota, K.:
Fas-ligand-mediated exocrinopathy resembling Sjögren's syndrome in mice transgenic for IL-10.
J Immunol 162:2488-2494, 1999
7. Usui, J., Takemura, H., Yuhara, T., Akama, T., Suzuki, H., Yamane, K., and Sumida, T.:
Dieulafoy's lesion of the esophagus as a probable complication of Takayasu's arteritis.
J Rheumatol 26: 454-456, 1999
8. Suzuki, M., Katsube, Y., Suzuki, H., Takemura, H., and Sumida, T.:
Cloning and analysis of anti-double strand DNA IgG autoantibodies obtained by a phage-display method.
Int J Mol Med 3:385-390, 1999.
9. Keino, H., Matsumoto, I., Okada, S., Kurokawa, M., Kato, T., Tokuhisa, T., Taniguchi, M., Nishioka, K.,
and Sumida, T.:A single cell analysis of TCR AV24AJ18+ DN T cells.
Microbiol Immunol 43:577-584, 1999
10. Matsumoto, I., Maeda, T., Takemoto, Y., Hashimoto, Y., Kimura, F., Iwamoto, I., Saito, Y., Nishioka, K.,
and Sumida, T.:a-amylase function as salivary glands-specific self T cell epitopes in patients with Sjögren's syndrome.
Int J Mol Med 3:485-490, 1999
11. Murata, H., Nakauchi, H., and Sumida, T.:
Microchimerism in Japanese women patients with systemic sclerosis.
Lancet 354:220,1999.
12. Kitagawa, M., Mitsui, H., Nakamura, H., Yoshino, S., Miyakawa, S., Ochiai, N., Onobori, M., Suzuki, H.,
and Sumida, T.:Differential regulation of rheumatoid synovial cell interleukin-12 production by tumor necrosis factor alphaand CD40 signals.
Arthritis Rheum 42:1917-1926, 1999
13. Akimoto, T., Akama, T., Kono, I., and Sumida, T.:
Relationship between clinical features and binding domains of anti-prothrombin autoantibodies in patientswith systemic lupus erythematosus and antiphospholipid syndrome.
Lupus 8:761-766, 1999.
14. Matsumoto, I., Okada, S., Kuroda, K., Iwamoto, I., Saito, Y., Tokuhisa, T., Nishioka, K., Sumida, T.:
Single cell analysis of T cells infiltrating labial salivary glands from patients with Sjögren's syndrome.
Int J Mol Med 4:519-527, 1999

1998 年
1. Katsube, Y., Suzuki, H., Muryoi, T., Sasaki, T.:
Analysis of k light chain contribution to anti-DNA antibody activity of a human VH4-21-encoded monoclonal
antibody(NE-1) by antibody-phage display technique.
Int J Mol Med 1:863-868, 1998
2. Nishioka, K., Hasunuma, T., Kato, T., Sumida, T., and Kobata, T.:
Apoptosis in theumatoid arthritis: A novel pathway in regulation of synovial tissue (Review).
Arthritis Rheum 41:1-9, 1998
3. Fujisawa, K., Okamoto, K., Murata, H., Hasunuma, T., Sumida, T., and Nishioka, T.:
Evidence for autoantigens of env/tax proteins in HTLV-I tax transgenic mice.
Arthritis Rheum 41:101-109, 1998.
4. Sumida, T., Hasunuma, T., Asahara, H., Maeda, T., and Nishioka, K.:
Rheumatoid arthritis and apoptosis. (Review)
Int Med 37:184-188, 1998
5. Okamoto, K., Asahara, H., Kobayashi, T., Matsuno, T., H, Hasunuma., T, Kobata., T, Sumida., andNishioka, K.:
Potential Induction of apoptosis in rheumatoid synovium by FAS ligand gene transfer.
Gene Therapy 5:331-338, 1998
6. Kita, Y., Kuroda, K., Mimori, T., Hashimoto, T., Tananiti, K., Saito, Y., Iwamoto, I., and Sumida, T.:T cell receptor clonotypes in skin lesions From Patientswith systemic lupus erythematosus.
J Investi Dermatol.110:41-46, 1998
7. Maeda, T., Webb, D.R., Kobata, T., Hirsose, S., Shirai, T., Nishioka, K., and Sumida, T.:
Deletion of signaling molecule gene resembling the cytoplasmic domain of Igb in autoimmune prone mice.
Int Immunol 6:815-821, 1998
8. Takemura, H., Suzuki, H., Fujisawa, H., Yuhara, T., Akama, T., Yamane, K., and Kashiwagi, H.:
Enhanced IL-6 production by cultured fibroblasts from patients with systemic sclerosis in response to plateletderived growth factor (PDGF).
J Rheumatol 25:1534-1539, 1998
9. Kaneko, S., Nagata, M., Takemura, H., Yuhara, T., Akama, T., Suzuki, H., Yamane, K., Kashiwagi, H.:
Gelatinous transformation of bone marrow with pancypeniai n an emaciatedpatient with systemic lupus
erythematosus.
Jpn J Rheumatol. 8:167-173, 1998

10. Imamura, F., Aono, H., Hasunuma, T., Sumida, T., Tateishi, H., Maruo, S., and Nishioka, K.:
Monoclonality of synoviocytes are responsible for rapid progression of bone destruction in rheumatoid
arthritis.
Arthritis Rheum 41:1979-1986, 1998
11. Matsumura, R., Umemiya, K., Kagami, M., Tomioka, H., Tanebe, E., Sugiyama, T., Sueishi, M.,
Nakajima, A., Azuma, M., Okumura, K., and Sumida, T.:
Glandular and Extraglandular expression of Fas-Fas ligand and apoptosis in patients with Sjögren's
syndorome.
Clin Exp Rheumatol. 16:561-568, 1998
12. Sumida, T., Maeda, T., Taniguchi, M., Nishioka, K., and Stohl, W.:
TCR AV24 Gene Expression in Double Negative T Cells in Systemic Lupus Erythematosus.
Lupus 7:565-568, 1998
13. Hasunuma, T., Sumida, T., and Nishioka, K.:
Human T cell leukemia virus type-1 and rheumatoid arthritis.
Int Rev Immunol 17:291-307, 1998.