SAFETY DATA SHEETS
Invivoscribe® RNA Sensitivity Panels

This document includes the Safety Data Sheets for reagents included in Invivoscribe RNA Sensitivity Panels, Catalog Numbers listed below.

Catalog Number

Description

40870030

Sensitivity Panel - IVS-0003 Clonal Control RNA

40870110

Sensitivity Panel - IVS-0011 Clonal Control RNA

40870150

Sensitivity Panel - IVS-0015 Clonal Control RNA

40870200

Sensitivity Panel - IVS-0020 Clonal Control RNA

40870320

Sensitivity Panel - IVS-0032 Clonal Control RNA

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Invivoscribe® RNA Sensitivity Panels
Conforms to HCS 2021 – Unites States

SAFETY DATA SHEET
Section 1: Identification
GHS product identifier :100% IVS-0003 Sensitivity RNA
10-1 IVS-0003 Sensitivity RNA
10-2 IVS-0003 Sensitivity RNA
10-3 IVS-0003 Sensitivity RNA
10-4 IVS-0003 Sensitivity RNA
10-5 IVS-0003 Sensitivity RNA
10-6 IVS-0003 Sensitivity RNA
100% IVS-0011 Sensitivity RNA
10-1 IVS-0011 Sensitivity RNA
10-2 IVS-0011 Sensitivity RNA
10-3 IVS-0011 Sensitivity RNA
10-4 IVS-0011 Sensitivity RNA
10-5 IVS-0011 Sensitivity RNA
10-6 IVS-0011 Sensitivity RNA
100% IVS-0015 Sensitivity RNA
10-1 IVS-0015 Sensitivity RNA
10-2 IVS-0015 Sensitivity RNA
10-3 IVS-0015 Sensitivity RNA
10-4 IVS-0015 Sensitivity RNA
10-5 IVS-0015 Sensitivity RNA
10-6 IVS-0015 Sensitivity RNA
100% IVS-0020 Sensitivity RNA
10-1 IVS-0020 Sensitivity RNA
10-2 IVS-0020 Sensitivity RNA
10-3 IVS-0020 Sensitivity RNA
10-4 IVS-0020 Sensitivity RNA
10-5 IVS-0020 Sensitivity RNA
10-6 IVS-0020 Sensitivity RNA
100% IVS-0032 Sensitivity RNA
10-1 IVS-0032 Sensitivity RNA
10-2 IVS-0032 Sensitivity RNA
10-3 IVS-0032 Sensitivity RNA
10-4 IVS-0032 Sensitivity RNA
10-5 IVS-0032 Sensitivity RNA
10-6 IVS-0032 Sensitivity RNA
Product typePart number :40830240
40830250
40830260
40830270
40830280
40830290
40830300
40830800
40830810
40830820
40830830
40830840
40830850
40830860
40831080
40831090
40831100
4083111040831120
4083113040831140
40831430
40831440
40831450
40831460
40831470
40831480
40831490
40832270
40832280
40832290
40832300
40832310
40832320
40832330:

Other means of identification :100% IVS-0003 Sensitivity RNA
10-1 IVS-0003 Sensitivity RNA
10-2 IVS-0003 Sensitivity RNA
10-3 IVS-0003 Sensitivity RNA
10-4 IVS-0003 Sensitivity RNA
10-5 IVS-0003 Sensitivity RNA
10-6 IVS-0003 Sensitivity RNA
100% IVS-0011 Sensitivity RNA
10-1 IVS-0011 Sensitivity RNA
10-2 IVS-0011 Sensitivity RNA
10-3 IVS-0011 Sensitivity RNA
10-4 IVS-0011 Sensitivity RNA
10-5 IVS-0011 Sensitivity RNA
10-6 IVS-0011 Sensitivity RNA
100% IVS-0015 Sensitivity RNA
10-1 IVS-0015 Sensitivity RNA
10-2 IVS-0015 Sensitivity RNA
10-3 IVS-0015 Sensitivity RNA
10-4 IVS-0015 Sensitivity RNA
10-5 IVS-0015 Sensitivity RNA
10-6 IVS-0015 Sensitivity RNA
100% IVS-0020 Sensitivity RNA
10-1 IVS-0020 Sensitivity RNA
10-2 IVS-0020 Sensitivity RNA
10-3 IVS-0020 Sensitivity RNA
10-4 IVS-0020 Sensitivity RNA
10-5 IVS-0020 Sensitivity RNA
10-6 IVS-0020 Sensitivity RNA
100% IVS-0032 Sensitivity RNA
10-1 IVS-0032 Sensitivity RNA
10-2 IVS-0032 Sensitivity RNA
10-3 IVS-0032 Sensitivity RNA
10-4 IVS-0032 Sensitivity RNA
10-5 IVS-0032 Sensitivity RNA
10-6 IVS-0032 Sensitivity RNA

LiquidRelevant identified issues of the substance or mixture and uses advised against
Identified uses For use as qualitative PCR controls.
Restrictions on use

SDS-RNA Sensitivity Panels Rev. A | October 2022:

For professional users only.

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Invivoscribe® RNA Sensitivity Panels

Section 1: Identification
Supplier’s details:

Invivoscribe, Inc.
10222 Barnes Canyon Road, Building 1
San Diego, CA
92121 USA
Tel: 1 858 224 6000
Toll Free: 1 866 623 8105
Email: customerservice@invivoscribe.com
Website: invivoscribe.com

Emergency telephone (with hours of operation):

1 866 623 8105
8 AM – 5 PM PST

Section 2. Hazards Identification
OSHA/HCS status:

Classification of the substance or mixture:

While this material is not considered hazardous by the OSHA Hazard Communication Standard(29 CFR 1910:1200), this SDS contains valuable information critical to the safe handling andproper use of the product. This SDS should be retained and available for employees and otherusers of this product.
Not classified.

::No signal word.
No known significant effects or critical hazards.

:
:
:
:
:

Not applicable.
Not applicable.
Not applicable.
Not applicable.
None known.

GHS label elements
Signal word
Hazard statements
Precautionary statements
Prevention
Response
Storage
DisposalHazards not otherwise classified

Section 3. Compositions/information on ingredients
Substance/mixture: Mixture
Other means of identification: Not available.
There are no additional ingredients present which, within the current knowledge of the supplier and in the concentrations applicable, areclassified as hazardous to health or the environment and hence require reporting in this section.
Occupational exposure limits, if available, are listed in Section 8.

Section 4. First aid measures
Description of necessary first aid measures
Eye contact: Immediately flush eyes with plenty of water, occasionally lifting the upper and lower eyelids. Check forand remove any contact lenses. Get medical attention if irritation occurs.
Inhalation: Remove victim to fresh air and keep at rest in a position comfortable for breathing. Get medical
attention if symptoms occur.
Skin contact: Flush contaminated skin with plenty of water. Get medical attention if symptoms occur.
Ingestion: Wash out mouth with water. If material has been swallowed and the exposed person is conscious,
give small quantities of water to drink. Do not induce vomiting unless directed to do so by medical
personnel. Get medical attention if symptoms occur.

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Section 4. First aid measures
Most important symptoms/effects, acute and delayed
Potential acute health effects
Eye contact: No known significant effects or critical hazards.
Inhalation: No known significant effects or critical hazards.
Skin contact: No known significant effects or critical hazards.
Ingestion: No known significant effects or critical hazards.
Over-exposure signs/symptoms
Eye contact
Inhalation
Skin contact
Ingestion::::

No known significant effects or critical hazards.
No known significant effects or critical hazards.
No known significant effects or critical hazards.
No known significant effects or critical hazards.

Indication of immediate medical attention and special treatment needed, if necessary
Notes to physician: Treat symptomatically. Contact poison treatment specialist immediately if large quantities have been
ingested or inhaled.
Specific treatments: No specific treatment.
Protection of first aiders: No action shall be taken involving any personal risk or without suitable training.
See toxicological information (Section 11)

Section 5. Fire-fighting measures
Extinguishing media
Suitable extinguishing media
Unsuitable extinguishing media
Specific hazards arising from the chemical
Hazardous thermal decomposition products
Special protective actions for fire-fighters

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:
:
:
:

Special protective equipment for fire-fighters:

Use an extinguishing agent suitable for the surrounding fire.
None known.
In a fire or if heated, a pressure increase will occur and the container may burst.
No specific data.
Promptly isolate the scene by removing all persons from the vicinity of the incident if
there is a fire. No action shall be taken involving personal risk or without suitabletraining.
Fire-fighters should wear appropriate protective equipment and self-contained
breathing apparatus (SCBA) with a full face-piece operated in positive pressure
mode.

Section 6. Accidental release measures
Personal precautions, protective equipment and emergency procedures
For non-emergency personnel : No action shall be taken involving any personal risk or without suitable training.
Evacuate surrounding areas. Keep unnecessary and unprotected personnel from entering. Do nottouch or walk through spilled material. Put on appropriate personal protective equipment.
For emergency responders: If specialized clothing is required to deal with the spillage, take note of any information in Section 8
on suitable and unsuitable materials. See also the information in “For non-emergency personnel”.
Environmental precautions: Avoid dispersal of spilled material and runoff and contact with soil, waterways, drains, and sewers.
Inform the relevant authorities if the product has caused environmental pollution (sewers,
waterways, soil or air).
Methods and materials for containment and cleaning up
Small spill : Stop leak if without risk. Move containers from spill area. Dilute with water and mop up if water soluble. Alternatively, or
if water soluble, absorb with an inert dry material and place in an appropriate waste disposal container. Dispose of via alicensed waste disposal contractor.

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Section 6. Accidental release measures
Large spill :Stop leak if without risk. Move containers from spill area. Prevent entry into sewers, water courses, basements or
confined areas. Wash spillages into an effluent treatment plant or proceed as follows. Contain and collect spillage with
non-combustible, absorbent material e.g. sand, earth, vermiculite or diatomaceous earth and place in container for
disposal according to local regulations (see Section 13). Dispose of via a licensed waste disposal contractor. Note: see
Section 1 for emergency contact information and Section 13 for waste disposal.

Section 7. Handling and storage
Precautions for safe handlingProtective measures
Advice on general occupational hygiene

Conditions for safe storage, including any incompatibilities:::

Put on appropriate personal protective equipment (see Section 8)..
Eating, drinking and smoking should be prohibited in areas where thismaterial is handled, stored and processed. Workers should wash
hands and face before eating, drinking and smoking. See also Section
8 for additional information on hygiene measures.
Store in accordance with local regulations. Store in original container
protected from direct sunlight in a dry, cool and well-ventilated area,
away from incompatible materials (see Section 10) and food anddrink. Keep container tightly closed and sealed until ready for use.
Containers that have been opened must be carefully resealed andkept upright to prevent leakage. Do not store in unlabeled containers.
Use appropriate containment to avoid environmental contamination.
See Section 10 for incompatible materials before handling or use.

Section 8. Exposure to controls/personal protection
Control parameters
Occupational exposure limits
None.
Appropriate engineering controls
Environmental exposure controls::

Good general ventilation should be sufficient to control worker exposure to airborne contaminants.
Emissions from ventilation or work process equipment should be checked to ensure they comply
with the requirements of environmental protection legislation.

Individual protection measures
Hygiene measures: Wash hands, forearms and face thoroughly after handling chemical products, before eating, smoking andusing the lavatory and at the end of the working period. Appropriate techniques should be used to remove
potentially contaminated clothing. Wash contaminated clothing before reusing. Ensure that eyewash
stations and safety showers are close to the workstation location.
Eye/face protection: Safety eyewear complying with an approved standard should be used when a risk assessment indicated this isnecessary to avoid exposure to liquid splashes, mists, gases or dusts. In contact is possible, the following
protection should be worn, unless the assessment indicates a higher degree of protection: safety glasses withside-shields.
Skin protection
Hand protection:

Body protection:

Other skin protection:

Respiratory protection :Chemical-resistant, impervious gloves complying with and approved standard should be worn at all times
when handling chemical products if a risk assessment indicates this is necessary.
Personal protective equipment for the body should be selected based on the task being performed and therisks involved and should be approved by a specialist before handling this product.
Appropriate footwear and any additional skin protection measures should be selected based on the task being
performed and the risks involved and should be approved by a specialist before handling this product.
Based on the hazard and potential for exposure, select a respirator that meets the appropriate standard or
certification. Respirators must be used according to a respiratory protection program to ensure proper fitting,training, and other important aspects of use.

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Section 9. Physical and chemical properties
Appearance
Physical state
Color
Odor
Odor threshold
pH
Melting/freezing point
Initial boiling point and boiling range
Flash point
Evaporation rate
Flammability (solid, gas)
Lower and upper explosive (flammable) limits
Vapor pressure
Vapor density
Relative density
Solubility
Solubility in water
Partition coefficient: n-octanol/water
Auto-ignition temperature
Decomposition temperature
Viscosity
Flow time (ISO 2431)

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:
:

Liquid. [Clear.]
Colorless.
Slight.
Not available.
Not available.
Not available.
Not available.
Does not flash.
Not available.
Not available.
Not available.
Not available.
Not available.
Not available.
Not available.
Not available.
Not applicable.
Not available.
Not available.
Not available.
Not available.

Section 10. Stability and reactivity
Reactivity :Chemical stability
Possibility of hazardous reactions
Conditions to avoid
Incompatible materials
Hazardous decomposition products

:
:
:
:
:

No dangerous reaction known under conditions of normal use.
The product is stable.
Under normal conditions of storage and use, hazardous reactions will not occur.
No specific data.
Reactive or incompatible with the following materials: oxidizing materials.
Under normal conditions of storage and use, hazardous decomposition products should not
be produced.

Section 11. Toxicological information
Information on toxicological effects
Acute toxicity
There is no data available.
Irritation/Corrosion
There is no data available.
Sensitization
There is no data available.
Mutagenicity
There is no data available.
Carcinogenicity
There is no data available.
Reproductive toxicity
There is no data available.
Teratogenicity
There is no data available.

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Section 11. Toxicological information
Specific Target organ toxicity (single exposure)
There is no data available.
Specific Target organ toxicity (repeated exposure)
There is no data available.
Aspiration hazard
There is no data available.
Information on the likely routes of exposure: Routes on entry anticipated: Oral, Dermal, Inhalation.
Potential acute health effects
Eye contact
Inhalation
Skin contact
Ingestion::::

No known significant effects or critical hazards.
No known significant effects or critical hazards.
No known significant effects or critical hazards.
No known significant effects or critical hazards.

Symptoms related to the physical, chemical and toxicological characteristics
Eye contact: No known significant effects or critical hazards.
Inhalation: No known significant effects or critical hazards.
Skin contact: No known significant effects or critical hazards.
Ingestion: No known significant effects or critical hazards.
Short term exposure
Potential immediate effects: No known significant effects or critical hazards.
Potential delayed effects: No known significant effects or critical hazards.
Long term exposure
Potential immediate effects: No known significant effects or critical hazards.
Potential delayed effects: No known significant effects or critical hazards.
Potential chronic health effects
General: No known significant effects or critical hazards.
Carcinogenicity: No known significant effects or critical hazards.
Mutagenicity: No known significant effects or critical hazards.
Reproductive toxicity: No known significant effects or critical hazards.
Numerical measures of toxicity
Acute toxicity estimates
There is no data available.

Section 12. Ecological information
Toxicity
There is no data available.
Persistence and degradability
There is no data available.
Bioaccumulative potential
There is no data available.
Mobility in soil
Soil/water partition coefficient (Koc)
Other adverse effects

SDS-RNA Sensitivity Panels Rev. A | October 2022::

Not available.
No known significant effects or critical hazards.

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Section 13. Disposal considerations
Disposal methods:

The generation of waste should be avoided or minimized wherever possible. Disposal of this product, solution andany by-products should comply with the requirements of environmental protection and waste disposal legislation
and any regional local authority requirements. Dispose of surplus and non-recyclable products via a licensed waste
disposal contractor. Waste should not be disposed of untreated to the sewer unless fully compliant with therequirements of all authorities with jurisdiction. Waste packaging should be recycled. Incineration or landfill should
only be considered when recycling is not feasible. This material and its container must be disposed of in a safe way.
Empty containers or liners may retain some product residues. Avoid dispersal of spilled material and runoff andcontact with soil, waterways, drains and sewers.

Section 14. Transport information
DOT Classification

IMDG

IATA

UN number

Not regulated.

Not regulated.

Not regulated.

UN proper shipping name

-

-

-

Transport hazard class(es)

-

-

-

Packing group

-

-

-

Environmental Hazards

No.

No.

No.
AERG : Not applicableSpecial precautions for user:

Transportation in bulk according to IMO instruments:

Transport within user’s premises: always transport in closed containers that are
upright and secure. Ensure that persons transporting the product know what to
do in the event of an accident or spillage.
Not available.

Section 15. Regulatory information
U.S. Federal regulations:

Clean Air Act Section 112 (b) Hazardous Air Pollutants (HAPs) :Clean Air Act Section 602 Class I Substances:

TSCA 8(a) CDR Exempt/Partial exemption: Not determined.
Clean Water Act (CWA) 311: Edetic Acid; Hydochloric Acid.
ListedNot listed

Clean Air Act Section 602 Class II Substances
DEA List I Chemicals (Precursor Chemicals)
DEA List II Chemicals (Essential Chemicals)

Not listed
Not listed
Not listed:::

SARA 302/304
Composition/information on ingredients
Name

%

EHS

Hydrochloric acid

0.001Yes.

SARA 304 RQ

SARA 302 TPQ

SARA 304 RQ(lbs)(gallons)(lbs)(gallons)

500

-

5000

-

:

634763213.6 lbs / 288182499 kg:

Not applicable.
No products were found

:
:
:
:

None of the components are listed.
None of the components are listed.
None of the components are listed.
None of the components are listed.
This product does not require a Safe Harbor warning under California Prop. 65.

SARA 311/312
Classification
Composition/information on ingredients
State regulations
Massachussetts
New York
New Jersey
Pennsylvania
California Prop. 65

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Section 15. Regulatory information
International regulations
Chemical Weapon Convention List Schedules I, II & III Chemicals
Not Listed.
Montreal Protocol
Not Listed.
Stockholm Convention on Persistent Organic Pollutants
Not Listed.
Rotterdam Convention on Prior Informed Consent (PIC)
Not Listed.
UNECE Aarhus Protocol on POPs and Heavy Metals
Not Listed.
Inventory list
United States (TSCA 8b):

All components are active or exempted.

Section 16. Other information
Procedure used to derive the classification
Classification
Not classified.
History
Date of issue/Date of revision
Date of previous issue
VersionInternal code
Prepared by
Key to abbreviations

Justification

:
:
:
:
:
:

4/15/2021
Not applicable.
1651-004
Invivoscribe, Inc.
ATE = Acute Toxicity Estimate
BCF = Bioconcentration Factor
GHS = Globally Harmonized System of Classification and Labelling of Chemicals
IATA = International Air Transport Association
IBC = Intermediate Bulk Container
IMGD = International Maritime Dangerous Goods
LogPow = logarithm of the octanol/water portion coefficient
MARPOL = International Convention for the Prevention of Pollution From Ships, 1973 as
modified by the Protocol of 1978 (“Marpol” = maritime pollution)
N/A = Not available
SGG = Segregation GroupUN = United Nations

Notice to reader
To the best of our knowledge, the information contained herein is accurate. However, neither the above-named supplier, nor any of its subsidiaries, assumes
any liability whatsoever for the accuracy or completeness of the information contained herein.
Final determination of suitability of any material is the sole responsibility of the user. All materials may present unknown hazards and should be used withcaution. Although certain hazards are described herein, we cannot guarantee that these are the only hazards that exist.

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