Biosimilars

Research-Grade Biosimilar Monoclonal Antibodies
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Research-Grade Biosimilar Monoclonal Antibodies
Bio X Cell InVivoSIM™ non-therapeutic antibodies are research-grade biosimilar monoclonal antibodies that have the same active biological component
as the original therapeutic antibodies. Biosimilars make it possible to study the biological effects of a drug without the need to source an expensive
pharmaceutical-grade therapeutic. Our InVivoSIM™ antibodies feature greater than 95% purity and are free of preservatives, stabilizers, and carrier
proteins. InVivoSIM™ antibodies are screened for murine pathogens and protein aggregation, feature binding validation via Immunoblot and are
guaranteed to contain less than 1 endotoxin unit per milligram. InVivoSIM™ antibodies are for Research Use Only (RUO) and are not for therapeutic use.
α-human CD20 (Rituximab Biosimilar)

α-human HER2 (Trastuzumab Biosimilar)

α-human PD-1 (Nivolumab Biosimilar)

α-human CTLA-4 (Ipilimumab Biosimilar)

InVivoSIMTM
CatalogProduct Name

Application

InVivoSIM™ anti-human C5 (Eculizumab Biosimilar)

Inhibition of the activation of C5, Functional assays, ELISA, IP

SIM0011

InVivoSIM™ anti-human CD20 (Rituximab Biosimilar)

FC, ELISA, WB

SIM0008

InVivoSIM™ anti-human CTLA-4 (Ipilimumab Biosimilar)

CTLA-4 neutralization, FC, ELISA, WB

SIM0004

InVivoSIM™ anti-human EGFR (Cetuximab Biosimilar)

GFR blockade, ELISA, FC

SIM0002
SIM0005

InVivoSIM™ anti-human HER2 (Trastuzumab Biosimilar)

FC, ELISA, IHC, WB

InVivoSIM™ anti-human IL-6R (Tocilizumab Biosimilar)

Functional assays, ELISA

SIM0014

InVivoSIM™ anti-human IL-17A (Secukinumab Biosimilar)

Functional assays, ELISA, IF, IHC, FC

SIM0013SIM0003

InVivoSIM™ anti-human PD-1 (Nivolumab Biosimilar)

Blocking of PD-1/PD-L signaling, FC, IHC, WB

InVivoSIM™ anti-human PD-1 (Pembrolizumab Biosimilar)

Blocking of PD-1/PD-L signaling, Functional assays

SIM0010

InVivoSIM™ anti-human PD-L1 (Atezolizumab Biosimilar)

FC, WB

SIM0009

InVivoSIM™ anti-human TNFα (Adalimumab Biosimilar)

TNFα neutralization, FC, ELISA, IF, IP, IHC, WB

SIM0001

InVivoSIM™ anti-human TNFα (Infliximab Biosimilar)

TNFα neutralization, FC, ELISA, WB

SIM0006

InVivoSIM™ anti-human VEGF (Bevacizumab Biosimilar)

VEGF neutralization, FC, ELISA, IP, WB

SIM0007

InVivoSIM™ anti-human VEGFR-2 (Ramucirumab Biosimilar)

Functional assays, IHC, FC

SIM0012

Don’t see the antibody of your interest? Contact us for more information: customerservice@bioxcell.com
IF Immunofluorescence | IHC Immunohistochemistry | WB Western blot | IP Immunoprecipitation | FC Flow cytometry (requires flurochrome conjugation)

For over 20 years, scientists have trusted Bio X Cell as their go-to source for in vivo functional grade antibodies. This isreflected in over 15,000 peer-reviewed publications citing Bio X Cell products. We understand this responsibility is ofparamount importance and remain committed to producing antibodies of unparalleled quality and consistency, enabling
our partners around the globe to accelerate research and discoveries.
Bio X Cellbioxcell.com | 1.866.787.3444
customerservice@bioxcell.com
Conditions: For Research Use Only. Not for use in diagnostic or theraputic procedures. Not for resale.
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