Program
SFRR Australasia & Japan Conference 2022
Redox Pathways in Biology & Medicine
Monday 5 December
Registration Opens
Mihi whakatau

8:15 am

8:45-9:00 am

Morning Session 1
Plenary Lecture 9:00-9:40 am
Invited Speaker 9:40-10:10 am
Selected Talk 10:10-10:30 am

Morning Tea

Rangihau Te Moana
Chair Tony Kettle
Kate Carroll
TBC
Phil Hogg
Multiple covalent protein forms: new look at the mature functional protein
Pramod Subedi The identification and characterisation of an unusual disulfide bondforming protein from Salmonella typhimurium.

10:35-11:05 am

Morning Session 2Invited Speaker 11:05-11:35 am John Aitken
Selected Talk
11:35-11:55 am Judy DeHaan.
Selected Talk
Selected Talk
Selected Talk

Lunch

11:55-12:15 pm Julie Lim
12:15-12:35 pm Renita Martis
12:35-12:55 pm Annika SeddonPeter Sly
Joshua Chandler

Chair Nina Dickerhof
Oxidative stress in cystic fibrosis.
Oxidized methionine species in pediatric cystic fibrosis airways
implicate hypochlorous acid exposure in lung damage.

3:05-3:15 pm

Afternoon Session 4
Selected Talk
3:15-3:35 pm Ayaho Yamamoto
Selected Talk

3:35-3:55 pm Paul Witting

Selected Talk
Selected Talk

3:55-4:15 pm Belal Chami
4:15-4:35 pm Thomas O’Neil

Poster Session 1

Circadian regulation of glutathione homeostasis in the lens.
Cysteine analogues as protective agents against lens cataract.
Epigenetic regulation of gene expression following exposure toneutrophil oxidants.

1:00-2:00 pm

Afternoon Session 3
Plenary Speaker 2:00-2:40 pm
Selected Talk
2:40-3:00 pm

Afternoon Beak

Chair John Aitken & Judy DeHaan
Oxidative stress and fertility.
Novel antioxidant and anti-inflammatory treatments for diabeticcardiovascular complications.

4:35 pm -6:00 pm

Chair Louisa Ashby & Paul Witting
Environmentally persistent free radicals: Oxidative stress and related
gene expression effects on well-differentiated human nasal epithelium.
Neutrophil extracellular trap density increases with increasing
histopathological severity of Crohn’s disease
Can myeloperoxidase alone initiate early stages of colitis?
Defining and characterising mononuclear phagocyte populations
in human healthy and Crohn’s-affected tissue.
Six Poster Pitches
Abigail Schartfeger, Ansa Thomas, Emma Vlasuik,
Jia Jing Shao, Te Rina King-Hudson, Sana Kawaguchi

Social Get together 6:00 pm onwards at the Astro Lounge

1Tues 6 December
Dawn Dialogue

8:15-9:00 am

Chair Mark Hampton

10 min break
Morning Session 5
Plenary Lecture 9:10-9:50 am
Selected Talk
9:50-10:10 am
Selected Talk

Morning Tea

Chair Margreet Vissers
Ursula Jakob
Early life ROS as modulator of lifespan and age-associated diseases.
Heather Shearer A Streptococcus pneumoniae genome-wide screen identifies
genes that confer tolerance to hypothiocyanous acid.
10:10-10:30 am Nina Dickerhof Thiol-based antioxidant systems protect pathogens from hypothiocyanousacid.
10:35-11:00 amMorning Session 6Chair Andrew Bulmer & TBC
Invited Talk
11:00-11:30 am Gemma Figtree TBC
Selected Talk
11:30-11:50 am Shane Thomas The effect of 2-thioxanthines on the involvement of myeloperoxidase inabdominal aortic aneurysms.
Selected Talk
11:50-12:10 pm Xiaoying Wang Molecular MR imaging of unstable plaque targeting
myeloperoxidase activity in a rabbit atherothrombosis model.
Selected Talk
12:10-12:30 pm Steven Gieseg Scavenger receptor CD36 levels may be moderated by redox balance of
7,8-dihydroneopterin/neopterin with atherosclerotic plaqueInvited Speaker 12:30-1:00 pm Aki Hirayama
Serum multiple radical scavenging activity assay (MULTIS) as a
non-behavioural diagnostic biomarker for autism spectrum disorders.

Lunch
SFRR A AGM
SFRR J AGM

1:00-2:00
1:15-2:00 pm
1:15 -2:00 pm

Afternoon Session 7
Invited Speaker 2:00-2:30 pm
Selected Talk
2:30-2:45 pm
Selected Talk
Selected Talk

Afternoon Break

2:45-3:00 pm
3:00-3:15 pm

Chair Hirofumi Matsui
Yukio Nagasaki Antioxidant nanoparticle for oxidative stress diseases
Hayley Turnham The production of nanobodies as a tool for understanding ferritin in
C. elegans.
Zac Tillet
Developing conformationally selective nanobodies for peroxiredoxin 1.
Albaraa Mojadadi Characterising the effects of nano-selenium on metabolism andmicrobiome health in mouse models.

3:15-3:25 pm

Afternoon Session 8Chair Liz Ledgerwood
Selected Talk
3:25-3:45 pm Anitra Carr
Oxidative stress in sepsis: can vitamin C administration help?
Selected Talk
3:45-4:00 pm Carlos Smith Diaz Low maternal vitamin C during guinea pig pregnancy causes epigenetic
dysregulation in the hippocampus of offspring together with an
ADHD-related phenotype.
Selected Talk
4:00-4:20 pm Jereme Spiers
Identification of inflammatory nitric oxide signalling in brain-derived
extracellular vesicles using advanced surface analysis.

Poster Session 2 4:25 pm-6:00 pm

Six Poster Pitches TBC
Jennifer Supple, Chloe Mountain, Tamara Ortiz Cerda,
Nick Magon, Alice Au, Grace Borichevsky.

Conference Dinner Ilex Botanical Gardens 7:30 pm2Wednesday 7 December
Dawn Dialogue

8:15-9:00 am

Chair Mark Hampton

10 min break
Morning Session 9Plenary Lecture 9:10-9:50 am
Selected Talk
9:50-10:10 am
Selected Talk
Morning Tea

Chair Kate Carroll
Vadim Gladyshev TBC
Christine Winterbourn CO2/bicarbonate requirement for rapid inactivation of mammalian
GAPDH by low concentrations of H2O2.
10:10-10:30 am Guy Jameson
Ferroxidase reactivity of C. elegans ferritins.
10:35-11:00 am

Morning Session 10
Selected Speaker 11:00-11:20

Selected Talk

Chair Christoph Goebl & TBC
Margaret Sunde Competing roles for functional amyloid fibrils in programmed cell
death by necroptosis.
11:20-11:40
Vanessa Morris Cysteine oxidation triggers amyloid fibril formation of the tumor
suppressor p16.
11:40-11:55
Noralyn Manucat-Tan Hypochlorite – a novel inhibitor of amyloid beta aggregationand toxicity
11:55-12:10
Jake Anderson Examining the reactivity and speciation of selenoneine in vitro via
synchrotron radiation.
12:10-12:25 pm Gawain McColl Optogenetic triggered lipid peroxidation.

Lunch

12:30 pm – 1:30 pm

Selected Talk
Selected Talk
Selected Talk

Afternoon Session 11Plenary Lecture 1:30-2:10 pm
Selected Talk

2:10-2:30 pm

Selected Talk
Selected Talk
Selected Talk

2:30-2:45 pm
2:45-3:00 pm
3:00-3:15 pm

Closing Address 3:15-3:30(Executive committee meeting for SFRRA&J)

Chair Mike Berridge & Martinna Paumann-Page
Hirofumi Matsui A novel cancer therapy using proton beam: an integrated proton
dynamic therapy, iPDT.
Bob Anderson Ubiquinone negatively affects the activity of bioreductive prodrugs against
hypoxic tumour cells.
Martina Paumann-Page Peroxidasin as a modulator of cancer cell invasion.
Patries Herst
Metabolic flexibility and metastasis in a murine breast cancer model.
Yuta Koda
Design of nanomedicine based on polycysteine suppressing C26-tumor
growth on a xenograft mouse model.

Rangihau Te Moana
Tony Kettle, Louisa Ashby et al3