PharmaceuticalPureFlo® Z-Series
Mini Capsule Filters

Typical Uses
Applications
Prefiltration
Bioburden Reduction
Sterile Filtration

PureFlo® Z-Series Mini Capsule Filters are gammastable and ideally suited for integration into singleuse applications. These filter capsules feature
an asymmetric hydrophilic PES membrane that
demonstrates exceptional capacity and flow
performance in liquid applications. The Z-Series Mini
capsule filters offer small- to mid-scale filtration in avariety of applications in the biopharmaceutical industry.
The Z-Series product family has been designed foreasy pre- and post-use integrity testing, assuring easy
wetting for quick and accurate integrity test results.

Process Fluids*
WFI
BufferCell culture medium
Bulk drug substance
Final drug product*Chemical compatibility information available upon request.

The compact design and available inlet and outlet
fittings allow efficient integration of Z-Series Mini
Capsules Filters into a wide range of single-use systems.
Z-Series Disc Capsule Filters provide biopharmaceuticalmanufacturers with a filtration solution configured tomeet their process needs.

Materials of Construction

Media:Polyethersulfone (PES)Media Supports:Polyester
Cage, Core, and Shell: Polypropylene
End Caps:
Nylon
O-Rings:
Silicone

Fitting Connections

See ordering guide for availability. (Custom adaptors available upon request)

Nominal Dimensions

Body Length: 60 mm (2.3”) Diameter: 60 mm (2.3”)

Effective Filtration Area

Available from 200 cm2 - 500 cm2 (0.22 ft2 - 0.54 ft2) see ordering guide for detail.

Operating Conditions

Integrity Testing*

Maximum Operating Pressure

Liquid: 5.5 bar (80 psi) at 22°C (72°F)

Maximum Forward Differential Pressure

5 bar (72 psi) at 22°C (72°F)

Maximum Reverse Differential Pressure

2.1 bar (30 psi) at 22°C (72°F)

Maximum Operating Temperature

80°C (176°F)

0.1 μm (see ordering guide for grades)

60% isopropyl alcohol bubble point ≥ 1.6 bar (23 psi) using air at 22°C

0.2 μm (see ordering guide for grades)

Water bubble point ≥ 3.5 bar (50 psi) using air at 22°C

USP Class VI

All components or raw materials used in this product conform to the requirements of USP Class VI
Biological Reactivity Tests for Plastics.

USP Cleanliness

Effluent from this product meets the requirements for a “non-fiber releasing” filter as defined by 21 CFR 210.3 (b) (6) and theharmonized requirements set forth by the USP <788>, EP, and JP for Particulate Matter in Injections.

Bacterial Endotoxins

An aqueous extraction of this product contains <0.25 EU/ml as determined by the Limulus Amebocyte
Lysate (LAL) Test.

Bacterial Retention

0.1 μm and 0.2 μm grades are quantitatively retentive towards Brevundimonas diminuta (ATCC #19146) at a minimum challenge
level of 107 CFU per cm2 of filtration area, consistent with ASTM F838-05.

Sterilization

This product can be autoclaved up to 25 cycles at 125 °C (257 °F) for 30 minutes. This product is compatible with gamma
irradiation up to 50 kGy.

*All filters are 100% integrity tested.

FILTRATIONFILTRATIONTECHNOLOGIESTECHNOLOGIESPureFlo® Z-Series Mini Capsule Filters
PureFlo Z-Series Mini Capsule Filters Ordering Guide

Filtration Media Grades
SINGLE LAYER

DUAL LAYER
PES with built-in (fine) PES
prefilter (ZS)
ZS010 = 0.1 μm
ZS020 = 0.2 μm
ZS045 = 0.45 μm

PES (S)
S004 = 0.04 μm
S010 = 0.1 μm
S020 = 0.2 μm
S045 = 0.45 μm
S065 = 0.65 μm
S080 = 0.8 μm
S120 = 1.2 μm

PES with built-in (coarse) PES
prefilter (XS)
XS010 = 0.1 μm
XS020 = 0.2 μm

Uniform particle size distribution

Wide particle size distribution

Lowest contaminant load

Highest contaminant load

PureFlo
Z-Series
Mini
CapsuleMZP =Z-Series
Mini
CapsuleNominalFiltration
Area

Filter Media GradeSelect from Filtration Media
Grades (above)

A= 200 cm2
B= 300 cm2
C= 400 cm2
D= 500 cm2

InletFitting
1H
1Q
1QF
2H
2Q
2QP
2QF3H5HLFLMMT
BH

Outlet Fitting

Options

1H = 1/8” hose barb
1Q = 1/8” male quick coupling
1QF = 1/8” female quick coupling with metal
latch
2H = 1/4” hose barb
2H-FB = 1/4” hose barb with filling bell
2H-FC = 1/4” hose barb with filling bell with cap
2Q = 1/4” male quick coupling
2QP = 1/4” male quick coupling (for plastic latch)
2QF = 1/4” female quick coupling with metallatch
3H = 3/8” hose barb
5H = 9/16” hose barb
LF = female Luer lock
LM = male Luer lock
MT = 1/2” tri-clamp
BH = 3/16’’ hose barb

Vent & Drain- N = No vent/drain- NI = No vent/drainnear inlet- NO = No vent/drainnear outlet(Leave blank for one vent/drain near inlet and one
vent/drain near outlet)

Example: MZPZS020ALMLM (Z-Series Mini Capsule, 0.2 μm PES final membrane with built-in (fine) PES prefilter, 200 cm2, male luer lock
inlet/outlet)
Custom adapters are available upon request.

Saint-Gobain Performance Plastics
Filtration Technologies
50 W. Watkins Mill Rd
Gaithersburg, MD 20878 USATel: (301) 407-2720
Fax: (240) 566-5774
www.filtration-fls.saint-gobain.com

IMPORTANT: It is the user’s responsibility to ensure the suitability and safety of Saint-Gobain Performance Plastics
products for all intended uses and that the materials to be used comply with all applicable regulatory requirements.
This product is not intended for use in or with a medical device or to diagnose, treat, cure, or prevent any disease.
Saint-Gobain Performance Plastics assumes no responsibility for any product failures that occur due to misuseof the materials it provides arising out of the design, fabrication or application of the products into which thematerials are incorporated.
WARRANTY: Except for products which have a specific written warranty, Saint-Gobain Performance Plastics
products are sold without any guaranty and/or warranty. The only obligation under any applicable productwarranty will be to replace any portion proving defective, or at our option, to refund the purchase price thereof.
SAINT-GOBAIN PERFORMANCE PLASTICS DISCLAIMS ALL IMPLIED WARRANTIES OF MERCHANTABILITY AND
FITNESS FOR A PARTICULAR PURPOSE.

PureFlo, C-Flex, Pure-Fit, and SIB are registered trademarks of Saint-Gobain Corporationor an affiliated company.
Copyright 2017 Saint-Gobain. All rights reserved.

SGHZ-C-QS-PD-TS017
Rev A. 1118