SAFETY DATA SHEET
according to GB/T 16483 and GB/T 17519

Progesterone Formulation
Version
4.2

Revision Date:
2024/04/06

SDS Number:
5155471-00011

Date of last issue: 2023/09/30
Date of first issue: 2019/10/17

1. PRODUCT AND COMPANY IDENTIFICATION
Product name:

Progesterone Formulation

Manufacturer or supplier's details
Company: Organon & Co.
Address:

30 Hudson Street, 33nd floor
Jersey City, New Jersey, U.S.A 07302

Telephone:+1-551-430-6000

Emergency telephone number :+1-215-631-6999

E-mail address

EHSSTEWARD@organon.com:

Recommended use of the chemical and restrictions on use
Recommended use: Pharmaceutical
Restrictions on use: Not applicable

2. HAZARDS IDENTIFICATION
Emergency Overview
Appearance
Colour
Odour

:
:
:

Crystalline powder
white to off-whiteodourlessSuspected of causing cancer. May damage fertility. May damage the unborn child. May cause
harm to breast-fed children. Toxic to aquatic life. Very toxic to aquatic life with long lasting effects.
GHS Classification
Carcinogenicity:

Category 2

Reproductive toxicity:

Category 1A

Short-term (acute) aquatic
hazard:Category 2

Long-term (chronic) aquatic
hazard:Category 1

Effects on or via lactation

GHS label elements

1 / 16

SAFETY DATA SHEET
according to GB/T 16483 and GB/T 17519

Progesterone Formulation
Version
4.2

Revision Date:
2024/04/06

SDS Number:
5155471-00011

Date of last issue: 2023/09/30
Date of first issue: 2019/10/17

Hazard pictograms:

Signal word:

DangerHazard statements:

H351 Suspected of causing cancer.
H360FD May damage fertility. May damage the unborn child.
H362 May cause harm to breast-fed children.
H401 Toxic to aquatic life.
H410 Very toxic to aquatic life with long lasting effects.

Precautionary statements:

Prevention:
P201 Obtain special instructions before use.
P202 Do not handle until all safety precautions have been readand understood.
P260 Do not breathe dust.
P263 Avoid contact during pregnancy/ while nursing.
P264 Wash skin thoroughly after handling.
P270 Do not eat, drink or smoke when using this product.
P273 Avoid release to the environment.
P280 Wear protective gloves/ protective clothing/ eye protection/ face protection.
Response:
P308 + P313 IF exposed or concerned: Get medical advice/attention.
P391 Collect spillage.
Storage:
P405 Store locked up.
Disposal:
P501 Dispose of contents/ container to an approved waste
disposal plant.

Physical and chemical hazards
Not classified based on available information.
Health hazards
Suspected of causing cancer. May damage fertility. May damage the unborn child. May cause
harm to breast-fed children.
Environmental hazards
Toxic to aquatic life. Very toxic to aquatic life with long lasting effects.
Other hazards which do not result in classification
Dust contact with the eyes can lead to mechanical irritation.
Contact with dust can cause mechanical irritation or drying of the skin.
May form explosible dust-air mixture if dispersed.

2 / 16

SAFETY DATA SHEET
according to GB/T 16483 and GB/T 17519

Progesterone Formulation
Version
4.2

Revision Date:
2024/04/06

SDS Number:
5155471-00011

Date of last issue: 2023/09/30
Date of first issue: 2019/10/17

3. COMPOSITION/INFORMATION ON INGREDIENTS
Substance / Mixture:

MixtureComponents
Chemical name
Progesterone
Titanium dioxide

CAS-No.
57-83-013463-67-7

Concentration (% w/w)>= 25 -< 30>= 0.1 -< 1

4. FIRST AID MEASURES
General advice:

If inhaled:

In case of skin contact:

In case of eye contact:

If swallowed:

Most important symptoms
and effects, both acute anddelayed:Protection of first-aiders:

Notes to physician:

In the case of accident or if you feel unwell, seek medical advice immediately.
When symptoms persist or in all cases of doubt seek medical
advice.
If inhaled, remove to fresh air.
Get medical attention.
In case of contact, immediately flush skin with soap and plentyof water.
Remove contaminated clothing and shoes.
Get medical attention.
Wash clothing before reuse.
Thoroughly clean shoes before reuse.
If in eyes, rinse well with water.
Get medical attention if irritation develops and persists.
If swallowed, DO NOT induce vomiting.
Get medical attention.
Rinse mouth thoroughly with water.
Suspected of causing cancer.
May damage fertility. May damage the unborn child.
May cause harm to breast-fed children.
Contact with dust can cause mechanical irritation or drying of
the skin.
Dust contact with the eyes can lead to mechanical irritation.
First Aid responders should pay attention to self-protection,and use the recommended personal protective equipment
when the potential for exposure exists (see section 8).
Treat symptomatically and supportively.

5. FIREFIGHTING MEASURES
Suitable extinguishing media:

Unsuitable extinguishingmedia
Specific hazards during firefighting::

Water spray
Alcohol-resistant foam
Carbon dioxide (CO2)
Dry chemicalHigh volume water jet
Avoid generating dust; fine dust dispersed in air in sufficientconcentrations, and in the presence of an ignition source is apotential dust explosion hazard.
3 / 16

SAFETY DATA SHEET
according to GB/T 16483 and GB/T 17519

Progesterone Formulation
Version
4.2

Revision Date:
2024/04/06

SDS Number:
5155471-00011

Date of last issue: 2023/09/30
Date of first issue: 2019/10/17

Do not use a solid water stream as it may scatter and spread
fire.
Exposure to combustion products may be a hazard to health.
Hazardous combustion products:

Carbon oxides
Nitrogen oxides (NOx)Specific extinguishing methods:

Special protective equipment
for firefighters:

Use extinguishing measures that are appropriate to local circumstances and the surrounding environment.
Use water spray to cool unopened containers.
Remove undamaged containers from fire area if it is safe to doso.
Evacuate area.
In the event of fire, wear self-contained breathing apparatus.
Use personal protective equipment.

6. ACCIDENTAL RELEASE MEASURES
Personal precautions, protec- :tive equipment and emergency procedures

Use personal protective equipment.
Follow safe handling advice (see section 7) and personal protective equipment recommendations (see section 8).

Environmental precautions:

Avoid release to the environment.
Prevent further leakage or spillage if safe to do so.
Retain and dispose of contaminated wash water.
Local authorities should be advised if significant spillages
cannot be contained.

Methods and materials forcontainment and cleaning up:

Sweep up or vacuum up spillage and collect in suitable container for disposal.
Avoid dispersal of dust in the air (i.e., clearing dust surfaces
with compressed air).
Dust deposits should not be allowed to accumulate on surfaces, as these may form an explosive mixture if they are released into the atmosphere in sufficient concentration.
Local or national regulations may apply to releases and disposal of this material, as well as those materials and items
employed in the cleanup of releases. You will need to determine which regulations are applicable.
Sections 13 and 15 of this SDS provide information regarding
certain local or national requirements.

:

Static electricity may accumulate and ignite suspended dust
causing an explosion.
Provide adequate precautions, such as electrical grounding
and bonding, or inert atmospheres.

7. HANDLING AND STORAGE
Handling
Technical measures

4 / 16

SAFETY DATA SHEET
according to GB/T 16483 and GB/T 17519

Progesterone Formulation
Version
4.2

Revision Date:
2024/04/06

SDS Number:
5155471-00011

Local/Total ventilation:

Advice on safe handling:

Avoidance of contact:

Storage
Conditions for safe storage:

Materials to avoid:

Packaging material:

Date of last issue: 2023/09/30
Date of first issue: 2019/10/17

If sufficient ventilation is unavailable, use with local exhaust
ventilation.
Avoid contact during pregnancy and while nursing.
Do not get on skin or clothing.
Do not breathe dust.
Do not swallow.
Avoid contact with eyes.
Wash skin thoroughly after handling.
Handle in accordance with good industrial hygiene and safety
practice, based on the results of the workplace exposure assessment
Keep container tightly closed.
Minimize dust generation and accumulation.
Keep container closed when not in use.
Keep away from heat and sources of ignition.
Do not eat, drink or smoke when using this product.
Take care to prevent spills, waste and minimize release to theenvironment.
None.
Keep in properly labelled containers.
Store locked up.
Keep tightly closed.
Store in accordance with the particular national regulations.
Do not store with the following product types:
Strong oxidizing agents
Unsuitable material: None known.

8. EXPOSURE CONTROLS/PERSONAL PROTECTION
Components with workplace control parameters
Components

Progesterone
Titanium dioxide

CAS-No.

Value type
Control parameBasis(Form ofters / Permissible
exposure)
concentration
57-83-0TWA
6 μg/m3 (OEB 4) Internal
Wipe limit
60 μg/100 cm2Internal
13463-67-7
PC-TWA
8 mg/m3
CN OEL(Total dust)
Further information: G2B - Possibly carcinogenic to humans
TWA (Res2.5 mg/m3
ACGIH
pirable par(Titanium dioxide)
ticulate matter)

This substance(s) is not bioavailable and therefore does not contribute to a dust inhalation
hazard.
Titanium dioxide

5 / 16

SAFETY DATA SHEET
according to GB/T 16483 and GB/T 17519

Progesterone Formulation
Version
4.2

Revision Date:
2024/04/06

Engineering measures

SDS Number:
5155471-00011:

Date of last issue: 2023/09/30
Date of first issue: 2019/10/17

Containment technologies suitable for controlling compounds
are required to control at source and to prevent migration of
the compound to uncontrolled areas (e.g., vacuum conveying
from a closed system, packout head with inflatable seal fromstationary container, ventilated enclosure, etc.).
All engineering controls should be implemented by facility
design and operated in accordance with GMP principles toprotect products, workers, and the environment.
Essentially no open handling permitted.
Use closed processing systems or containment technologies.

Personal protective equipment
Respiratory protection: If adequate local exhaust ventilation is not available or exposure assessment demonstrates exposures outside the recommended guidelines, use respiratory protection.
Filter type
: Combined particulates and organic vapour type
Eye/face protection: Wear safety glasses with side shields or goggles.
If the work environment or activity involves dusty conditions,mists or aerosols, wear the appropriate goggles.
Wear a faceshield or other full face protection if there is apotential for direct contact to the face with dusts, mists, oraerosols.
Skin and body protection: Work uniform or laboratory coat.
Additional body garments should be used based upon thetask being performed (e.g., sleevelets, apron, gauntlets, disposable suits) to avoid exposed skin surfaces.
Use appropriate degowning techniques to remove potentiallycontaminated clothing.
Hand protection
Material
Remarks
Hygiene measures:

Chemical-resistant gloves::

Consider double gloving.
If exposure to chemical is likely during typical use, provide
eye flushing systems and safety showers close to the working place.
When using do not eat, drink or smoke.
Wash contaminated clothing before re-use.
The effective operation of a facility should include review ofengineering controls, proper personal protective equipment,
appropriate degowning and decontamination procedures,industrial hygiene monitoring, medical surveillance and theuse of administrative controls.

9. PHYSICAL AND CHEMICAL PROPERTIES
Appearance:

Crystalline powder

Colour:white to off-white

Odour

:

odourless6 / 16

SAFETY DATA SHEET
according to GB/T 16483 and GB/T 17519

Progesterone Formulation
Version
4.2

Revision Date:
2024/04/06

SDS Number:
5155471-00011

Date of last issue: 2023/09/30
Date of first issue: 2019/10/17

Odour Threshold:

No data available

pH:

No data available

Melting point/freezing point:

126 °C

Initial boiling point and boiling
range

:

No data available

Flash point:

Not applicable

Evaporation rate:

Not applicable

Flammability (solid, gas):

No data available

Upper explosion limit / Upper
flammability limit:

No data available

Lower explosion limit / Lower
flammability limit:

No data available

Vapour pressure:

Not applicable

Relative vapour density:

Not applicable

Relative density:

No data available

Density:

No data available

Solubility(ies)
Water solubility:

practically insoluble

Partition coefficient: noctanol/water
Auto-ignition temperature:

Not applicable:

No data available

Decomposition temperature:

No data available

Viscosity
Viscosity, kinematic:

Not applicable

Explosive properties:

Not explosive

Oxidizing properties:

The substance or mixture is not classified as oxidizing.

Molecular weight:

No data available

Particle characteristics
Particle size:

No data available
7 / 16

SAFETY DATA SHEET
according to GB/T 16483 and GB/T 17519

Progesterone Formulation
Version
4.2

Revision Date:
2024/04/06

SDS Number:
5155471-00011

Date of last issue: 2023/09/30
Date of first issue: 2019/10/17

10. STABILITY AND REACTIVITY
Reactivity
Chemical stability
Possibility of hazardous reactions
Conditions to avoid
Incompatible materials
Hazardous decomposition
products:::

Not classified as a reactivity hazard.
Stable under normal conditions.
Dust can form an explosive mixture in air.

:::

Avoid dust formation.
None.
No hazardous decomposition products are known.

11. TOXICOLOGICAL INFORMATION
Exposure routes:

Inhalation
Skin contact
Ingestion
Eye contact

Acute toxicity
Not classified based on available information.
Components:
Progesterone:
Acute dermal toxicity:

LD50 (Rat): > 2,000 mg/kg
Remarks: Based on data from similar materials

Titanium dioxide:
Acute oral toxicity:

LD50 (Rat): > 5,000 mg/kg

Acute inhalation toxicity:

LC50 (Rat): > 6.82 mg/l
Exposure time: 4 h
Test atmosphere: dust/mist
Assessment: The substance or mixture has no acute inhalation toxicity

Skin corrosion/irritation
Not classified based on available information.
Components:
Progesterone:
SpeciesResultRemarks:::

RabbitNo skin irritation
Based on data from similar materials

Titanium dioxide:

8 / 16

SAFETY DATA SHEET
according to GB/T 16483 and GB/T 17519

Progesterone Formulation
Version
4.2

Revision Date:
2024/04/06

SpeciesResultSDS Number:
5155471-00011::

Date of last issue: 2023/09/30
Date of first issue: 2019/10/17

RabbitNo skin irritation

Serious eye damage/eye irritation
Not classified based on available information.
Components:
Progesterone:
SpeciesResult
MethodRemarks::::

RabbitNo eye irritation
OECD Test Guideline 405
Based on data from similar materials

Titanium dioxide:
SpeciesResult::RabbitNo eye irritation

Respiratory or skin sensitisation
Skin sensitisation
Not classified based on available information.
Respiratory sensitisation
Not classified based on available information.
Components:
Progesterone:
Test Type
Exposure routes
Species
MethodResultRemarks

:
:
:
:
:
:

Maximisation Test
Skin contact
RabbitOECD Test Guideline 406
negative
Based on data from similar materials

Titanium dioxide:
Test Type
Exposure routes
SpeciesResult::::Local lymph node assay (LLNA)
Skin contact
Mouse
negative

Germ cell mutagenicity
Not classified based on available information.
Components:
Progesterone:
Genotoxicity in vitro:

Test Type: Bacterial reverse mutation assay (AMES)
9 / 16

SAFETY DATA SHEET
according to GB/T 16483 and GB/T 17519

Progesterone Formulation
Version
4.2

Revision Date:
2024/04/06

SDS Number:
5155471-00011

Date of last issue: 2023/09/30
Date of first issue: 2019/10/17

Method: OECD Test Guideline 471
Result: negative
Remarks: Based on data from similar materials
Test Type: DNA damage and repair, unscheduled DNA synthesis in mammalian cells (in vitro)
Method: OECD Test Guideline 482
Result: negative

Genotoxicity in vivo:

Test Type: Mammalian erythrocyte micronucleus test (in vivo
cytogenetic assay)
Species: Monkey
Application Route: Subcutaneous
Result: negative
Test Type: Unscheduled DNA synthesis (UDS) test withmammalian liver cells in vivo
Species: Rat
Application Route: Ingestion
Result: negative

Titanium dioxide:
Genotoxicity in vitro:

Test Type: Bacterial reverse mutation assay (AMES)
Result: negative

Genotoxicity in vivo:

Test Type: In vivo micronucleus test
Species: Mouse
Result: negative

:
:
:
:

Mouse, female
Subcutaneous
104 weeks
positive:

Limited evidence of carcinogenicity in animal studies

:
:
:
:
:
:

Rat
inhalation (dust/mist/fume)
2 Years
OECD Test Guideline 453
positive
The mechanism or mode of action may not be relevant in hu-

Carcinogenicity
Suspected of causing cancer.
Components:
Progesterone:
Species
Application RouteExposure time
ResultCarcinogenicity - Assessment
Titanium dioxide:
Species
Application RouteExposure time
MethodResultRemarks

10 / 16

SAFETY DATA SHEET
according to GB/T 16483 and GB/T 17519

Progesterone Formulation
Version
4.2

Revision Date:
2024/04/06

SDS Number:
5155471-00011

Date of last issue: 2023/09/30
Date of first issue: 2019/10/17

mans.
This substance(s) is not bioavailable and therefore does notcontribute to a dust inhalation hazard.
Carcinogenicity - Assessment:

Limited evidence of carcinogenicity in inhalation studies withanimals.

Reproductive toxicity
May damage fertility. May damage the unborn child.
May cause harm to breast-fed children.
Components:
Progesterone:
Effects on fertility:

Test Type: Fertility/early embryonic development
Species: Rat
Application Route: Subcutaneous
Result: positive

Effects on foetal development:

Test Type: Fertility/early embryonic development
Species: Rat
Application Route: Subcutaneous
Result: positive

Reproductive toxicity - Assessment:

Positive evidence of adverse effects on sexual function andfertility from human epidemiological studies., Clear evidenceof adverse effects on development, based on animal experiments., Studies indicating a hazard to babies during the lactation period

STOT - single exposure
Not classified based on available information.
STOT - repeated exposure
Not classified based on available information.
Repeated dose toxicity
Components:
Titanium dioxide:
Species
NOAEL
Application RouteExposure time

:
:
:
:

Rat
24,000 mg/kg
Ingestion
28 DaysSpecies
NOAEL
Application RouteExposure time

:
:
:
:

Rat
10 mg/m3
inhalation (dust/mist/fume)
2 yr

11 / 16

SAFETY DATA SHEET
according to GB/T 16483 and GB/T 17519

Progesterone Formulation
Version
4.2

Revision Date:
2024/04/06

SDS Number:
5155471-00011

Date of last issue: 2023/09/30
Date of first issue: 2019/10/17

Aspiration toxicity
Not classified based on available information.
Experience with human exposure
Components:
Progesterone:
General Information:

Target Organs: Endocrine system
Symptoms: Effects on fertility:

LC50 (Danio rerio (zebra fish)): > 1 - 10 mg/l
Exposure time: 96 h
Test substance: Water Accommodated Fraction
Method: OECD Test Guideline 203
Remarks: Based on data from similar materials

Toxicity to daphnia and otheraquatic invertebrates:

EC50 (Daphnia magna (Water flea)): > 1 mg/l
Exposure time: 48 h
Test substance: Water Accommodated Fraction
Remarks: Based on data from similar materials

Toxicity to fish (Chronic toxicity):

NOEC (Pimephales promelas (fathead minnow)): 0.000010
mg/l
Exposure time: 21 d

12. ECOLOGICAL INFORMATION
Ecotoxicity
Components:
Progesterone:
Toxicity to fish

Toxicity to daphnia and other :aquatic invertebrates (Chronic toxicity)
M-Factor (Chronic aquatic:
toxicity)
Titanium dioxide:
Toxicity to fish

NOEC (Daphnia magna (Water flea)): 0.1 mg/l
Exposure time: 26 d
1,000

:

LC50 (Oncorhynchus mykiss (rainbow trout)): > 100 mg/l
Exposure time: 96 h
Method: OECD Test Guideline 203

Toxicity to daphnia and otheraquatic invertebrates:

EC50 (Daphnia magna (Water flea)): > 100 mg/l
Exposure time: 48 h

Toxicity to algae/aquaticplants:

EC50 (Skeletonema costatum (marine diatom)): > 10,000 mg/l
Exposure time: 72 h

Toxicity to microorganisms:

EC50: > 1,000 mg/l
Exposure time: 3 h
12 / 16

SAFETY DATA SHEET
according to GB/T 16483 and GB/T 17519

Progesterone Formulation
Version
4.2

Revision Date:
2024/04/06

SDS Number:
5155471-00011

Date of last issue: 2023/09/30
Date of first issue: 2019/10/17

Method: OECD Test Guideline 209
Persistence and degradability
Components:
Progesterone:
Biodegradability:

Result: Readily biodegradable.
Remarks: Based on data from similar materials:

Pow: 3.65
Method: OECD Test Guideline 117

Bioaccumulative potential
Components:
Progesterone:
Partition coefficient: noctanol/water
Mobility in soil
No data available
Other adverse effects
No data available
13. DISPOSAL CONSIDERATIONS
Disposal methods
Waste from residues:

Contaminated packaging:

Do not dispose of waste into sewer.
Dispose of in accordance with local regulations.
Empty containers should be taken to an approved waste handling site for recycling or disposal.
If not otherwise specified: Dispose of as unused product.

14. TRANSPORT INFORMATIONInternational Regulations
UNRTDGUN number
Proper shipping name

:
:

Class
Packing group
LabelsEnvironmentally hazardous

:
:
:
:

UN 3077
ENVIRONMENTALLY HAZARDOUS SUBSTANCE, SOLID,
N.O.S.
(Progesterone)
9
III
9
yes

IATA-DGR
UN/ID No.
Proper shipping name::UN 3077
Environmentally hazardous substance, solid, n.o.s.
13 / 16

SAFETY DATA SHEET
according to GB/T 16483 and GB/T 17519

Progesterone Formulation
Version
4.2

Revision Date:
2024/04/06

SDS Number:
5155471-00011

Date of last issue: 2023/09/30
Date of first issue: 2019/10/17

:
:
:
:

(Progesterone)
9
III
Miscellaneous
956

:

956

:

yes

IMDG-CodeUN number
Proper shipping name

:
:

Class
Packing group
LabelsEmS Code
Marine pollutant

:
:
:
:
:

UN 3077
ENVIRONMENTALLY HAZARDOUS SUBSTANCE, SOLID,
N.O.S.
(Progesterone)
9III
9F-A, S-F
yes

Class
Packing group
LabelsPacking instruction (cargo
aircraft)Packing instruction (passenger aircraft)
Environmentally hazardous

Transport in bulk according to Annex II of MARPOL 73/78 and the IBC CodeNot applicable for product as supplied.
National Regulations
GB 6944/12268
UN number
Proper shipping name

:
:

Class
Packing group
LabelsMarine pollutant

:
:
:
:

UN 3077
ENVIRONMENTALLY HAZARDOUS SUBSTANCE, SOLID,
N.O.S.
(Progesterone)
9
III
9
no

Special precautions for user
The transport classification(s) provided herein are for informational purposes only, and solely
based upon the properties of the unpackaged material as it is described within this Safety Data
Sheet. Transportation classifications may vary by mode of transportation, package sizes, and variations in regional or country regulations.
15. REGULATORY INFORMATION
National regulatory information
Law on the Prevention and Control of Occupational Diseases
Regulation on the Administration of Precursor Chemicals
Catalogue and Classification of Precursor Chemicals:

Not listed

Yangtze River Protection Law
This product does not contain any dangerous chemicals prohibited for inland river transport.
14 / 16

SAFETY DATA SHEET
according to GB/T 16483 and GB/T 17519

Progesterone Formulation
Version
4.2

Revision Date:
2024/04/06

SDS Number:
5155471-00011

Date of last issue: 2023/09/30
Date of first issue: 2019/10/17

The components of this product are reported in the following inventories:
IECSC: not determinedAICS:

not determinedDSL:

not determined

Revision Date:

2024/04/06

Further information
Sources of key data used tocompile the Safety Data
Sheet

:

Internal technical data, data from raw material SDSs, OECD
eChem Portal search results and European Chemicals Agency, http://echa.europa.eu/

Date format:

yyyy/mm/dd

16. OTHER INFORMATION

Full text of other abbreviations
ACGIH: USA. ACGIH Threshold Limit Values (TLV)
CN OEL: Occupational exposure limits for hazardous agents in theworkplace - Chemical hazardous agents.
ACGIH / TWA
CN OEL / PC-TWA::

8-hour, time-weighted average
Permissible concentration - time weighted average

AIIC - Australian Inventory of Industrial Chemicals; ANTT - National Agency for Transport byLand of Brazil; ASTM - American Society for the Testing of Materials; bw - Body weight; CMR Carcinogen, Mutagen or Reproductive Toxicant; DIN - Standard of the German Institute forStandardisation; DSL - Domestic Substances List (Canada); ECx - Concentration associated with
x% response; ELx - Loading rate associated with x% response; EmS - Emergency Schedule;
ENCS - Existing and New Chemical Substances (Japan); ErCx - Concentration associated with
x% growth rate response; ERG - Emergency Response Guide; GHS - Globally Harmonized System; GLP - Good Laboratory Practice; IARC - International Agency for Research on Cancer; IATA
- International Air Transport Association; IBC - International Code for the Construction andEquipment of Ships carrying Dangerous Chemicals in Bulk; IC50 - Half maximal inhibitory concentration; ICAO - International Civil Aviation Organization; IECSC - Inventory of Existing Chemical Substances in China; IMDG - International Maritime Dangerous Goods; IMO - International
Maritime Organization; ISHL - Industrial Safety and Health Law (Japan); ISO - International Organisation for Standardization; KECI - Korea Existing Chemicals Inventory; LC50 - Lethal Concentration to 50 % of a test population; LD50 - Lethal Dose to 50% of a test population (Median
Lethal Dose); MARPOL - International Convention for the Prevention of Pollution from Ships;
n.o.s. - Not Otherwise Specified; Nch - Chilean Norm; NO(A)EC - No Observed (Adverse) EffectConcentration; NO(A)EL - No Observed (Adverse) Effect Level; NOELR - No Observable EffectLoading Rate; NOM - Official Mexican Norm; NTP - National Toxicology Program; NZIoC - New
Zealand Inventory of Chemicals; OECD - Organization for Economic Co-operation and Development; OPPTS - Office of Chemical Safety and Pollution Prevention; PBT - Persistent, Bioaccumulative and Toxic substance; PICCS - Philippines Inventory of Chemicals and Chemical Substances; (Q)SAR - (Quantitative) Structure Activity Relationship; REACH - Regulation (EC) No
1907/2006 of the European Parliament and of the Council concerning the Registration, Evaluation, Authorisation and Restriction of Chemicals; SADT - Self-Accelerating Decomposition Tem15 / 16

SAFETY DATA SHEET
according to GB/T 16483 and GB/T 17519

Progesterone Formulation
Version
4.2

Revision Date:
2024/04/06

SDS Number:
5155471-00011

Date of last issue: 2023/09/30
Date of first issue: 2019/10/17

perature; SDS - Safety Data Sheet; TCSI - Taiwan Chemical Substance Inventory; TDG - Transportation of Dangerous Goods; TECI - Thailand Existing Chemicals Inventory; TSCA - Toxic Substances Control Act (United States); UN - United Nations; UNRTDG - United Nations Recommendations on the Transport of Dangerous Goods; vPvB - Very Persistent and Very Bioaccumulative; WHMIS - Workplace Hazardous Materials Information System
Disclaimer
The information provided in this Safety Data Sheet is correct to the best of our knowledge, information and belief at the date of its publication. The information is designed only as a guidance forsafe handling, use, processing, storage, transportation, disposal and release and shall not be
considered a warranty or quality specification of any type. The information provided relates only
to the specific material identified at the top of this SDS and may not be valid when the SDS material is used in combination with any other materials or in any process, unless specified in the text.
Material users should review the information and recommendations in the specific context of theirintended manner of handling, use, processing and storage, including an assessment of the appropriateness of the SDS material in the user’s end product, if applicable.
CN / EN

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