The 47th NIPS International Symposium “Decoding Synapses”
Okazaki Conference Center (OCC), Okazaki, Aichi
October 26 – 28, 2016
Program
October 26 (Wed)8:15 – 9:00

Registration

9:00 – 9:05

Opening remarks
Keiji Imoto (Director General, NIPS, Japan)

9:05 – 9:10

Introduction
Masaki Fukata (NIPS, Japan)

Session 1:

Regulation of receptor trafficking
Chair: Toshihisa Ohtsuka (Univ of Yamanashi, Japan)

9:10 – 9:45
9:45 –10:20

S1

Masaki Fukata (NIPS, Japan)“Regulatory mechanisms for AMPA receptors through PSD-95”

S2

Katherine W Roche (NIH/NINDS, USA)
“PSD-95 plays diverse roles in regulating synaptic NMDA receptors”

S3Akihiko S Kato (Lilly Research Laboratory, USA)
“Selective pharmacological modulation of forebrain AMPA receptors:
Success in the development of TARP γ-8-dependent AMPA receptor
antagonist, TDAA”

10:20 – 10:55

10:55 – 11:10

Coffee BreakSpecial Lecture 1

11:10 – 12:00
12:00 – 12:10
12:10 – 13:15

Chair: Masaki Fukata (NIPS, Japan)
David S Bredt (Janssen Pharmaceutical Companies of Johnson and Johnson,USA)“Discovery of NACHO: An essential chaperone for presynaptic and postsynapticnicotinic acetylcholine receptors in brain”
Group photo
Lunch

Luncheon Satellite Seminar (Director-Invited Lecture)

12:15 – 13:05

Room B

Chair: Junichi Nabekura (NIPS, Japan)
Ryohei Yasuda (Max Planck Florida Institute, USA)
“Biochemical computation in single dendritic spines: implication in synapticplasticity”

1Session 2:

Trans-synaptic regulation
Chair: Yuko Fukata (NIPS, Japan)
S4

Eunjoon Kim (KAIST, Korea)“Regulation of neuronal synapses by the SALM/Lrfn family of synapticadhesion molecules”

S5

Katsuhiko Tabuchi (Shinshu Univ, Japan)“Distortion of the synaptic functions in the microcircuit of the brain in model
mice for neurodevelopmental disorders”

S6

Michisuke Yuzaki (Keio Univ, Japan)“Synaptic Ménage à Trois—A Bridge Over Troubled Synapses”

13:15 – 13:50

13:50 – 14:25

14:25 – 15:00
15:00 – 15:15

Coffee BreakSession 3:

Synaptic dynamics and plasticity I
Chair: Yasuo Mori (Kyoto Univ, Japan)
S7

Toshihisa Ohtsuka (Univ of Yamanashi, Japan)“Decoding short-term synaptic plasticity: implication of CAST
phosphorylation in control of synaptic plasticity at the excitatory synapses”

S8Shigeo Okabe (The Univ of Tokyo, Japan)“Maturation-dependent regulation of synaptic density and dynamics”

S9Naoki Matsuo (Osaka Univ, Japan)“Visualization and manipulation of memory engram”

15:15 – 15:50

15:50 – 16:25
16:25 – 17:00

17:00 – 17:15

17:15 – 17:30
17:35 – 18:00

ST1 Eisuke Koya (Univ of Sussex, UK)“Enhanced excitability of nucleus accumbens, but not orbitofrontal cortex
neuronal ensembles following sucrose memory recall: reversal byextinction”
ST2 Kazuhiko Yamaguchi (RIKEN, Japan)“Reassessment of synaptic plasticity in mutant mice carrying mutated
GluA2-CT with normal ability in motor learning: revival of LTD hypothesis”
Flash talk for poster presentations (2 min x 12 persons, FT1-FT12)

18:30 – 20:30

Dinner for invited speakers & informal discussion

October 27 (Thu)Special Lecture 2

9:00 – 9:50
9:50 – 10:05

Chair: Masaki Fukata (NIPS, Japan)
Masanobu Kano (The Univ of Tokyo, Japan)“Multiple phases of activity-dependent synapse elimination in the developingcerebellum”
Coffee Break2

Session 4:

10:05 – 10:40

Synaptic dynamics and plasticity II
Chair: Haruhiko Bito (The Univ of Tokyo, Japan)
S10 Keiko Tanaka-Yamamoto (KIST, Korea)“Timely regulated late endosome sorting for the maintenance of cerebellar
long-term depression”

10:40 –11:15

S11 Masahiko Watanabe (Hokkaido Univ, Japan)“Glutamate transporter GLAST controls synaptic wrapping by Bergmannglia and ensures proper wiring in Purkinje cells”

11:15 – 11:50

S12 Kazuo Emoto (The Univ of Tokyo, Japan)“Spatio-temporal regulation of dendrite development and remodeling”

11:50 – 13:00

Lunch

Special Lecture 3
Chair: Masaki Fukata (NIPS, Japan)
13:00 – 13:50
13:50 – 14:05

Session 5:

Daniel Choquet (CNRS-Bordeaux Univ, France)“The various roles of nanoscale AMPA receptor dynamics in synaptic plasticity”
Coffee BreakSynaptic imaging and manipulation I
Chair: Katherine W Roche (NIH/NINDS, USA)

14:05 – 14:40

S13 Hideji Murakoshi (NIPS, Japan)“Spatiotemporal manipulation and imaging of signaling molecules indendritic spines”

14:40 – 15:15

S14 Matthew J Kennedy (Univ of Colorado Denver Sch of Med, USA)
“Novel approaches for controlling synaptic and cellular function with light”

15:15 – 15:30
15:30 – 15:45

Session 6:

ST3 Shigeki Kiyonaka (Kyoto Univ, Japan)“Visualization of native AMPA receptors in live neurons by a novel chemicalapproach”
Coffee Break

Structural aspects of synaptic proteins
Chair: Makoto Kinoshita (Nagoya Univ, Japan)

15:45 – 16:20

S15 Shuya Fukai (The Univ of Tokyo, Japan)“Structural basis of splice insert-dependent synaptic adhesion mediated byreceptor protein tyrosine phosphatase ä”

16:20 – 16:55

S16 A Radu Aricescu (Univ Oxford, UK)“Structural basis for integration of GluD receptors within synaptic organizercomplexes”
316:55 – 17:10
17:10 – 17:25

ST4Haruka Munezane (The Univ of Tokyo, Japan)“The elucidation of the physiological function of CLAC-P/collagen XXV inneuromuscular development”

ST5 William P Dempsey (Univ of South California, USA)“In vivo single-cell labeling by confined primed conversion”

17:30 – 18:45

Poster session with coffee

18:45 – 20:30

Party for all participants & informal discussion

October 28 (Fri)
Session 7:

9:00 – 9:35
9:35 –10:10
10:10 – 10:25
10:25 – 10:40

Session 8:

Synaptic imaging and manipulation IIChair: Akihiko S Kato (Lilly Research Laboratory, USA)
S17 Junichi Nakai (Saitama Univ, Japan)“in vivo calcium imaging with genetically encoded calcium indicators andoptogenetics”
S18 Don B Arnold (Univ of South California, USA)
“Visualizing and ablating synapses in vivo using novel recombinant probes”
ST6Alvaro Carrier-Ruiz (The Univ of Tokyo, Japan)“Dentate granule cell activity during fear memory retrieval and extinction infreely moving mice”
Coffee BreakSynaptic circuit
Chair, Toshiya Manabe (The Univ of Tokyo, Japan)

10:40 – 11:15

S19 Yumiko Yoshimura (NIPS, Japan)“High reciprocal connectivity between clonal cortical neurons is establishedunder the guidance of epigenetic regulation”

11:15 –11: 50

S20 Haruhiko Bito (The Univ of Tokyo, Japan)“A critical role for activity-dependent Arc expression in long-term memory
via inverse synaptic tagging"

11:50 –11:55

Closing remarks
Masaki Fukata (NIPS, Japan)

11:55

Departures-------------------------------------------------------------------Presentation time, 25 min talk + 10 min discussion
Special lecture,

40 min talk + 10 min discussion

Short talk,

12 min talk + 3 min discussion-------------------------------------------------------------------4

Poster Presentations

P, Poster#; ST, Short talk#; FT, Flash talk#

Poster titles will be shown in the on-site program book.
P1-ST1Joe Ziminski, Sabine Hessler, Meike Sieburg, Gabriella Margetts-Smith, Hans S Crombag, andEisuke Koya
P2-ST2
Kazuhiko Yamaguchi, Shigeyoshi Itohara, and Masao Ito
P3-ST3
Shigeki Kiyonaka, Sho Wakayama, Itaru Arai, Wataru Kakegawa, Michisuke Yuzaki and Itaru
HamachiP4-ST4Haruka Munezane, Hiroaki Oizumi, Tomoyuki Yoshida, Tomoko Wakabayashi, Takeshi Iwatsubo
P5-ST5
William P Dempsey, Lada Georgieva, Patrick M Helbling, Ali Y Sonay, Thai V Truong, MichelHaffner, Periklis Pantazis
P6-ST6
Alvaro Carrier-Ruiz, Yuki Sugaya and Masanobu Kano
P7-FT1
Yoshihisa Nakahata, Kei Eto, Miho Watanabe, Hideji Murakoshi, Toshihiko Kuriu, Hiromi Hirata,
Hitoshi Ishibashi and Junichi Nabekura
P8-FT2Rizki Tsari Andriani and Yoshihiro KuboP9-FT3
Akihiro Shibata, Hideji Murakoshi
P10-FT4
Ryohei Akiyoshi, Hiroaki Wake, Daisuke Kato and Junichi Nabekura
P11-FT5
Hiromi Sano, Kenji F Tanaka and Atsushi Nambu

5P12-FT6
Mai Handa-Narumi, Takeshi Yoshimura, Tomohiro Torii, Hiroyuki Konishi, Hiroshi Kiyama andKazuhiro Ikenaka
P13-FT7
Tadahiro Nagaoka and Masashi Kishi
P14-FT8
Kazuki Obashi, Yasuhiro Inoue and Shigeo Okabe
P15-FT9
Jun Tsunoda, Chihong Song, Fabiana Lica Yakushiji, Takeshi Murata, Hiroshi Ueno, Junichi Takagi,Ryota Iino, Kazuyoshi Murata
P16-FT10
Kei Nakayama, Manabu Abe, Maya Yamazaki, Akihiro Fujikawa, Masaharu Noda, Akira Futatsugi,Katsuhiko Mikoshiba, Kenji Sakimura and Nobuyuki Shiina
P17-FT11
Hiroyuki Inada, Go Kato, Junichi Nabekura
P18-FT12
Etsuko Tarusawa, Makoto Sanbo, Masumi Hirabayashi, Takeshi Yagi and Yumiko Yoshimura
P19
Natsumi Ageta-Ishihara and Makoto Kinoshita
P20
Takeshi Yoshimura and Kazuhiro Ikenaka
P21
Kenta Kobayashi, Hiromi Sano, Shigeki Kato, Keisuke Kuroda, Shinichi Nakamuta, Tadashi Isa,Atsushi Nambu, Kozo Kaibuchi and Kazuto Kobayashi
P22
Yoko Yamagata, Yuchio Yanagawa and Keiji Imoto
P23
Akiyuki Nishimura, Caloline Sunggip, Takuro Numaga-Tomita and Motohiro Nishida
P24
Takuro Numaga-Tomita, Naoyuki Kitajima, Akiyuki Nishimura and Motohiro Nishida6

P25
Yuko Fukata, Norihiko Yokoi, Atsushi Sekiya, Tatsuro Murakami, Kenta Kobayashi and Masaki
FukataP26
Norihiko Yokoi, Yuko Fukata, Daisuke Kase, Taisuke Miyazaki, Martine Jaegle, Keiji Imoto, DiesMeijer, Masahiko Watanabe, Masaki Fukata-----------Preparation for poster, flash talk & short talk presentations<Poster>Poster boards are 90 cm in width X 120 cm in height.
Please display your poster from 15:00, Oct 26 (during the coffee break) in Room B, Okazaki
Conference Center, and keep your poster on the board for 3 days.
Core time for the presentation is from 17:30 to 18:45 on Oct 27.
<Flash talk>Prepare a 1 slide presentation in English. Your presentation will be 2 minutes in length (please notethat 2 min includes the time for presenters exchanging). This session has no discussion time.
Please send electric files (microsoft Powerpoint file and pdf file) for one presentation slide tokasosei@nips.ac.jp by Oct 18 5:00 PM. Our Symposium office will attach a slide showing yourname and affiliation with your slide. All the slides for Flash talk will be assembled in and presented
with our Symposium's MacBookAir.
Flash talk session will begin at 17:35 on Oct 26.
All the Flash talk presenters are requested to come to the stage of main hall (Room A) at 17:30 onOct 26 and wait in order of the presentation number (FT1-FT12).
<Short talk>
Short talk presentation will be 12 min talk and 3 min discussion.
*Please use your own laptop computer. Please bring and set your computer before the session
begins. Speakers are requested to be seated in the next speaker's seat area during the session

7