GEN 3
The new standard
for light bioprinting

LUMEN X TM GEN 3

2The new standard for light bioprinting.

SETTING THE STANDARD OF BIOPRINTING SINCE 2016

Developing solutions to maximize yourresearch and deliver greater insights on
the journey to create the future of health.
Since our inception, we have been committed to meeting our customers’ needs
by producing versatile, high-quality and easy-to-use systems and solutions. Our
mission is to provide tools with cutting-edge technology which make a meaningful impact in your work, delivering greater insights on the journey to createthe future of health.

CELLINK

Unleash the power of light
printing on your research.

3Experience the new standard for benchtop DLP
bioprinters. Built from the ground up with CELLINK’s cutting-edge technology and powered by
405 nm visible light, this system brings a newdegree of precision and utility to the light-based
bioprinter space.

Backed with years of customer suggestions, thethird generation of LUMEN X™ takes every needand detail into consideration. With a new robustand rethought design, as well as user-friendly
software, this printer makes light-based bioprinting a breeze – unlocking advantages across numerous applications.

4LUMEN X TM GEN 3

The new standard for light bioprinting.

CELLINK

5MORE FROM EVERY PRINTAchieve greater results with an array ofnew features and simplified workflows.
Designed for live cell printing
LUMEN X™ Gen 3 is built with live cell printing in mind. The new tighter temperature
control, a smooth printing mechanism, andsterility across the printing workflow join
together to increase cell viability. The autoclavable build platform has increased reusability without compromising on sterility.

Modular build platforms

Tight temperature control
Work with a wider than ever range ofmaterials or focus on studying the thermal
properties of a single material by setting
the temperature anywhere between room
temperature and 60°C.

Precise and complex printing

With an expanded range of build platforms,
print a variety of model sizes and materials
with ease and say goodbye to unnecessary
waste of photoinks.

An intuitive software combined with highfeature resolution and optimized photoinks
makes working on organ-on-a-chip models
and developing microfluidic chips an effortless experience.

Temperature range

Build volume

Pixel Resolution

RT*–60°C 35 μm

68x38x100 mm

Consistent prints – every time
With a uniform distribution of intensity
across the entire build platform, the LUMEN
X™ Gen 3 ensures consistent crosslinking ofphotoinks independent of position. Levellingup the ability for array printing.

Grayscale printing
Accurately tune the stiffness of your material and create biomechanical gradientson demand to capture the finer details of
in-vivo biology.

*Room/Ambient temperature

6LUMEN X TM GEN 3

The new standard for light bioprinting.

Building life
with light.

The LUMEN X™ is optimized to build hydrogel structures by beginning with a droplet oflight-sensitive, liquid PhotoInk™ in a vat. An
industrial blue-light projector exposes a series of images onto the vat, like a slideshow.
The areas of the droplet that are exposed
will crosslink and solidify into a single layer.
The build platform moves up to allow eachlayer to stack and build the part.

This powerful printing mechanism provides
users with the ideal entry into the worldof light bioprinting, with the backing andsupport of the leading bioprinting company. Enabling easy access to high precisionand versatile bioprinting for users to create
complex structures that mimic the architecture and function of natural tissues.

With the LUMEN X™ Gen 3, we invite you topush the limits of your research, widen yourhorizons and challenge you to IDEATE more
complex models, ILLUMINATE and bringthese to life with the LUMEN X™ and thus
CREATE the future of health.

CELLINK

7

LUMEN X TM GEN 3

8The new standard for light bioprinting.

Further reading

Versatility across numerous applications.

Microfluidics

Material development

Tissue engineering

Drug development

With high precision and resolution, the LUMEN X™ Gen 3
enables the creation of complex
microfluidic structures withintricate geometries for controlled fluid flow. Users can work
directly with cells or seed themlater. The LUMEN X™ eliminates
lengthy casting processes andfinally brings a much desired
time- and cost-effective solution for reproducible microfluidic
fabrication.

The LUMEN X™ allows users todevelop and use their own materials without workarounds orextra fees, opening the door forthe development of materials
with unique properties and novel
tissue engineering applications.
With precision control over all
key parameters like temperature, intensity and exposure
times, researchers can glean agreater understanding of theirmaterial’s behavior.

Supported by the DLP technology, the LUMEN X™ enables
researchers to address one of
the most long-standing challenges - fabricating complex
vascular networks. Coupled withgrayscale printing onboard forthe first time ever, the LUMEN
X™ Gen 3 truly unlocks a newdegree of capability in capturingin-vivo like conditions.

Drive down the cost of drug
development through models
that provide greater insight.
Accurately create diseased andhealthy tissue constructs readyto be dosed with compounds forearly-stage compound selection.

CELLINK

9With our unwavering commitment to your research success, our seasoned team of biomaterial experts have developed kits with recipes
and protocols, which take you from stock solutions to ready-to-print
photoinks optimized for use on the LUMEN X™ Gen 3.

Xcite
Xcite, CELLINK’s novel photoinitiator specifically designed for developing optimal
photoinks for light-based bioprinting. With
exceptional biocompatibility, gold standard
cell viability, and rapid polymerization properties, Xcite enables researchers to developintricate cellular structures at lightningspeeds.

Xsorb
Xsorb is a biocompatible photoabsorber,specifically formulated to enable complex
structures like microfluidic systems on
CELLINK light-based systems. Producedwith stringent quality control, Xsorb provides users with exceptional control, andprecision during the DLP printing process.

PEGDA X
Fine-tuned and tailored for optimal performance, PEGDA X is the go-to starting ink
for DLP printing. Blended with low molecular weight PEGDA, this ready-to-use
photoink provides users with a mechanicallyrobust material with high print fidelity.

PEGDA Soft
Customizable and easy to use, PEGDA Softstock solution is the ideal starting point for
researchers looking for a photosensitive
material with an inherent stiffness thatclosely mimics in-vivo conditions and provides an environment conducive to permeability dependent processes like nutrient,waste and gas exchange.

GelMA 95%
The cornerstone of live cell bioprinting,GelMA provides a biodegradable basematerial with tremendous cell attachment
capabilities and mechanical properties that
accurately capture physiological conditions.
Provided as a stock solution, researchers
have the freedom to make the most of thiswonder biomaterial’s tunability. Blend withproteins, growth factors or other photosensitive polymers like PEGDA, to create theideal recipe for your research application.

10IDEATE.
ILLUMINATE.
CREATE.

LUMEN X TM GEN 3

The new standard for light bioprinting.

CELLINK

11DNA STUDIO ILLUMINATE

The go-to-bioprinting
software, now fine-tuned
for light biofabrication.
Introducing for the first time DNA STUDIO ILLUMINATE, a fresh take on the world’s leading bioprinting
software tailored for light bioprinting and its applications. Available on-board the LUMEN X™ as well as anadvanced version for desktop machines. Guiding users
all the way from construct generation to monitoring
prints and ensuring repeatable success. Now packed
with the ability to alter shapes, develop arrays for mul-tiplexed printing, view microfluidic systems and, for the
first time, set up grayscale printing for biomechanicalgradients.
Thanks to close collaboration with users and the strong
foundations of DNA STUDIO, with ILLUMINATE webring an intuitive interface which packs all the features
necessary to bring your idea to life.

CELLINK12WEBEMAILPHONEwww.cellink.com

sales@cellink.com

US: +1 (833) CELLINK
EU: +46 311 287 00