ISSN 0914-9198

Journal ofTOXICOLOGICPATHOLOGY
http://wwwsoc.nii.ac.jp/jstp3/english/Journal.html

Vol. 23
No. 3Autumn
2010
Published by
The Japanese Society of Toxicologic Pathology
The Journal of Toxicologic Pathology has been selected for coverage in Thomson Reuters
products and services. Beginning with volume 21, number 1, year 2008, the journal isindexed and abstracted in:
Science Citation Index Expanded (also known as SciSearch R )Journal Citation Reports/Science Edition
Biological Abstracts
BIOSIS Previews

Editor-in-Chief
Dai Nakae, Tokyo
Editor Emeritus
Eisei Ishikawa (1988–1997)
Former Editors-in-Chief
Kunio Doi (1998–2003)
Kunitoshi Mitsumori (2003-2007)
Editorial Board (Editors)
Wijit Banlunara, Bangkok
Satoshi Furukawa, Saitama
Paul-Georg Germann, Barsbüttel
Katsumi Imaida, Kagawa
Keisuke Izumi, Tokushima
Hijiri Iwata, Itingen
Jong-Koo Kang, Cheongju
Osamu Katsuda, Nara
Wolfgang Kaufmann, Ludwigshafen
Yuji Oishi, Osaka
Kumiko Ogawa, Tokyo
Jin Ren, Shanghai
Hiroshi Satoh, Tokyo
John Curtis Seely, North Carolina

Makoto Shibutani, Tokyo
Kazumoto Shibuya, Tokyo
Masami Suzuki, Shizuoka
James Swenberg, North Carolina
Kazutoshi Tamura, Shizuoka
Leander Tryphonas, Ontario
Tetsuya Tsukamoto, Aichi
Masahiro Tsutsumi, Nara
Klaus Weber, Itingen
Midori Yoshida, TokyoNaomi Yoshimi, Okinawa
Katsuhiko Yoshizawa, Osaka

Description
The Journal of Toxicologic Pathology is an official periodical journal of the Japanese Society of Toxicologic Pathology. The journal
accepts original papers, short communications, case reports and review articles. One volume published each year is composed of fournumbers. Members of the Society are entitled to receive all publications in exchange for his or her membership fee. All articles
published in the Journal of Toxicologic Pathology represent the opinion(s) of the authors(s) and should not be construed to reflect theopinion of the Society.
The Journal of Toxicologic Pathology has been selected for coverage in Thomson Reuters products and services. Beginning withvolume 21, number 1, year 2008, the journal is indexed and abstracted in:◆ Science Citation Index Expanded (also known as SciSearch®)◆ Journal Citation Reports/Science Edition◆ Biological Abstracts◆ BIOSIS Previews
Mailing address: Dai Nakae, M.D., Ph.D., Editor-in-Chief
Editorial Office, Journal of Toxicologic Pathology, c/o Publication Center, IPEC, Inc., 1-24-12 Sugamo, Toshima,
Tokyo 170-0002, Japan
Journal of Toxicologic Pathology homepage: http://wwwsoc.nii.ac.jp/jstp3/english/Journal.html
Free access to full papers ofVols.1(1988)–10(1997): http://www.journalarchive.jst.go.jp/japanese/jnltop_ja.php?cdjournal=tox1988
Vol. 11 (1998) or later: http://www.jstage.jst.go.jp/browse/tox/-char/en
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Online ISSN 1881-915X
Cover: A: Cultured Japanese amberjack Seriola quinqueradiata suffering from ascites occurring in the winter, with pale coloration of the gills,a heart with a white membrane and a congested liver. The scale bar indicates 3 cm. g: gill. h: heart. l: liver. B: Histopathologicalfeatures of the kidney. Renal tubular epithelia are necrotized ( ). Some swollen reticular cells ( ) are observed in the hematopoietic
tissue. H&E. C: Histopathological features of the heart. Severe fibrin deposition ( ) occurs in the epicardium and the pericardial
cavity (pc). PTAH. ep: epicardium. pe: pericardium. D: Histopathological features of the liver. The hepatic parenchyma displays
many vacuolated spaces. Azan. E: Histopathological features of the liver. Dilated sinusoids contained many erythrocytes ( ) andeosinophilic materials ( ). Necrotic lesions ( ) were also observed around the dilated sinusoids. H&E. F: The hepatic vein showscongestion, while edema and fibrin deposition ( ) occur in the perivascular tissue. Azan. (See Kobayashi T, p.165–169)