Nagasaki University Priority Graduate Programs (NUPGP)
for Foreign Students in Biomedical Sciences(Master Course)

Syllabus
April, 2016 ～ March, 2017

Nagasaki University Graduate School of Biomedical Sciences

Nagasaki University Priority Graduate Programs (NUPGP)
for Foreign Students in Biomedical Sciences (Master Course)
contents
Subject
LectureMolecular Biology of Neurodegenerative Diseases Ⅱ
Analytical Chemistry ｉn Health and Environmental Sciences Ⅱ
Bioorganic Chemistry for Environmental Science Ⅱ
Pharmacology and Drug Discovery Ⅱ
Natural Product Chemistry for Infectious Diseases Ⅱ
Molecular Biology of Infectious Agents Ⅰ
Inorganic Chemistry ｉn Health and Environmental Sciences Ⅰ
Synthesis of Drugs for Infectious Diseases Ⅰ
Cell Biology for Health Science Ⅰ
Chemistry of Biofunctional Molecules for Infectious Diseases Ⅰ
Pharmaceutical Organic Chemistry for Infectious Diseases Ⅰ
Resources of Marine Natural Medicines for Infectious Diseases
Resources of Natural Medicines for Infectious Diseases
Exercise and Experiment
Exercise Biomedical Sciences [Cell Regulation]
Experiment Biomedical Sciences [Cell Regulation]
Exercise Biomedical Sciences [Pharmacology and Therapeutic Innovation]
Experiment Biomedical Sciences [Pharmacology and Therapeutic Innovation]
Exercise Biomedical Sciences [Pharmaceutical Chemistry]Experiment Biomedical Sciences [Pharmaceutical Chemistry]
Exercise Biomedical Sciences [Pharmaceutical Organic Chemistry]Experiment Biomedical Sciences [Pharmaceutical Organic Chemistry]
Exercise Biomedical Sciences [Chemistry for Pharmaceuticals]
Experiment Biomedical Sciences [Chemistry for Pharmaceuticals]
Exercise Biomedical Sciences [Genome-based Drug Discovery]
Experiment Biomedical Sciences [Genome-based Drug Discovery]
Exercise Biomedical Sciences [Molecular Pharmacology of infectious Agents]
Experiment Biomedical Sciences [Molecular Pharmacology of infectious Agents]
Exercise Biomedical Sciences [Natural Product Chemistry]Experiment Biomedical Sciences [Natural Product Chemistry]
Exercise Biomedical Sciences [Medicinal Plant Biochemistry]Experiment Biomedical Sciences [Medicinal Plant Biochemistry]
Exercise Biomedical Sciences [Structure Analysis for Chemicals]
Experiment Biomedical Sciences [Structure Analysis for Chemicals]
Exercise Biomedical Sciences [Chemistry of Biofunctional Molecules]
Experiment Biomedical Sciences [Chemistry of Biofunctional Molecules]
Exercise Biomedical Sciences [Hygienic Chemistry]Experiment Biomedical Sciences [Hygienic Chemistry]
Exercise Biomedical Sciences [Analytical Chemistry]Experiment Biomedical Sciences [Analytical Chemistry]
Exercise Biomedical Sciences [Pharmacotherapeutics]
Experiment Biomedical Sciences [Pharmacotherapeutics]
Exercise Biomedical Sciences [Pharmaceutical Informatics]
Experiment Biomedical Sciences [Pharmaceutical Informatics]
Exercise Biomedical Sciences [Pharmaceutics]
Experiment Biomedical Sciences [Pharmaceutics]

Credit

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開講期間／Class period

2016年度／Academic Year 前期／First Semester
2016/04/01 ~ 2016/09/27

必修選択／Required/Elective class

選択／elective

単位数(一般/編入/留学)／Credits
1.0(general/admission/overseas)

時間割コード／Time schedule code

20165503150110

科目番号／Subject code

科目ナンバリングコード／Numbering Code

BMMP51632783

授業科目名／Subject

Molecular Biology of Neurodegenerative I／Molecular Biology of Neurodegenerative Diseases
I

編集担当教員／Professor in charge ofputting together the course syllabus

岩田修永／Iwata Nobuhisa, 城谷

授業担当教員名（科目責任者）／Professor in charge of the subject

岩田

修永／Iwata Nobuhisa

授業担当教員名（オムニバス科目等）／Professor(s)岩田

修永／Iwata Nobuhisa, 城谷

科目分類／Class type

特別コースの授業科目／NUPGP

対象年次／Year

1, 2

学期／Semester

教室／Class room
対象学生（クラス等）

曜日・校時／Day・Period

月／Mon 255031501

圭朗／Shirotani Keiro, 浅井将／Asai Masashi

圭朗／Shirotani Keiro, 浅井将／Asai Masashi

講義形態／Class Form

講義／Lecture〔薬学〕各担当教員研究室／Laboratory/Object Student

Mastercourse

担当教員Eメールアドレス/E‑mail address

iwata‑n@nagasaki‑u.ac.jp, keiroshiro@nagasaki‑u.ac.jp, asai@nagasaki‑u.ac.jp

担当教員研究室/Laboratory

Gene‑based Drug Discovery

担当教員TEL/Tel

095‑819‑2435 (Iwata), 095‑819‑2436 (Shirotani), 095‑819‑2437 (Asai)

担当教員オフィスアワー/Office hours

Mon‑Fri. 13:00‑17:00

Better understanding of molecular mechanisms of dementia and neurodegenerative diseases
in addition to their clinical symptom and pathological features is requisite fordevelopment of more effective and safer medication. This class focuses on dementia andneurodegenerative diseases, such as Alzheimer s disease, and provides you with detailed
授業の概要及び位置づけ/Course Outline and molecular mechanisms and recent topics of the disease researches. A common keyword to thediseases isproteases , which play critical roles in the disease onsets andObjectives
developments. At the end of this class, you will be aware that down‑regulation or up‑
regulation of the proteases responsible for metabolism of pathogenic peptides would bepromising avenues for medication. This class also provides much knowledge and information
how we can utilize biotechnological techniques for development of new drugs.
To understand and to be able to summarize molecular mechanisms of the diseases and
授業到達目標/Goal
potential of biotechnology against the diseases.

授業方法（学習指導法）/Method

Lecture using PC‑based slide‑show presentation and printed materials.
Basics of enzymology, such as classification of enzymes, pathophysiological functions ofsome enzymes, t in addition to the clinical symptoms, the pathological features andmolecular mechanisms of the diseases, will be reviewed. The lecture also includes
essences to understand future drug developments and early diagnostic method based on the
genomic drug discovery concept, and proteomic analysis.

授業内容/Class outline/Con

キーワード/Key word
教科書・教材・参考書/Textbook,Teachingmaterial,and Reference book
成績評価の方法・基準等/Evaluation
受講要件（履修条件）/Requirements

1st: The clinical symptoms and the pathological features of neurodegenerative diseases[Iwata]2nd: The causal genes responsible for Alzheimer s disease pathogenesis and theirfunctions [Shirotani]
3rd: Molecular mechanism of the pathogenesis of Alzheimer s disease (1) [Iwata]
4th: Molecular mechanism of the pathogenesis of Alzheimer s disease (2) [Iwata]
5th: In vivo analysis of pathogenic mechanism of Alzheimer s disease using animal models(1) [Iwata]
6th: In vivo analysis of pathogenic mechanism of Alzheimer s disease using animal models(2) [Iwata]
7th: Current status of biomarkers and disease‑modifying drugs for Alzheimer s disease[Shirotani]
8th: Recent advances of Alzheimer s disease research [Asai]dementia, neurodegenerative diseases, Alzheimer's disease, neuropathologies, animalmodels, proteases, drug discovery, clinical biomarker
A handout of selected PowerPoint slides used in each lecture.
Active participation 40%, brief examination after the class 30% and report 30%
To whom take this class must have fundamental knowledge on neurobiology and molecularbiology.

1

アクセシビリティ/Accessibility

In order to ensure equal educational opportunities for all students, Nagasaki University
strives to remove societal barriers that may interfere with academic activities, and toprovide reasonable accommodations as necessary and appropriate. If you have any questions
or concerns regarding reasonable accommodations or other support in this class, pleasefeel free to talk to the instructor (contact information above), or contact the Student
Accessibility Office.
Student Accessibility Office contact information（TEL）095‑819‑2006（FAX）095‑819‑2948（E‑MAIL）support@ml.nagasaki‑u.ac.jp

備考（URL）/Remarks(URL)

http://www.alzforum.org/

学生へのメッセージ/Message for students

In most cases this research field is different from yours, but I hope you learn how to go
ahead with disease researches.

授業計画詳細／Course Schedule
回(日時)／Time(date and time)

授業内容／Contents

1st, 4/11

The clinical symptoms and the pathological features of neurodegenerative diseases [Iwata]

2nd, 4/18

The causal genes responsible for Alzheimer[Iwata]3rd, 4/25

Molecular mechanism of the pathogenesis of Alzheimers disease (1) [Asai]

4th, 5/2

Molecular mechanism of the pathogenesis of Alzheimers disease (2) [Asai]

In vivo analysis of pathogenic mechanism of Alzheimer[Iwata]In vivo analysis of pathogenic mechanism of Alzheimer[Iwata]s disease using animal models (1)5th, 5/9
6th, 5/16

s disease pathogenesis and their functions

s disease using animal models (2)7th, 5/23

Current status of biomarkers and disease‑modifying drugs for Alzheimer

8th, 6/3

Recent advances of Alzheimer

2s disease researchs disease

開講期間／Class period

2016年度／Academic Year 前期／First Semester
2016/04/01 ~ 2016/09/27

必修選択／Required/Elective class

選択／elective

単位数(一般/編入/留学)／Credits
1.0(general/admission/overseas)

時間割コード／Time schedule code

20165503100013

科目番号／Subject code

科目ナンバリングコード／Numbering Code

BMMP53332782

授業科目名／Subject

Analytical Chemistry I／Analytical Chemistry in Health and Environmental Sciences I

編集担当教員／Professor in charge ofputting together the course syllabus

黒田直敬／Naotaka Kuroda, 岸川

授業担当教員名（科目責任者）／Professor in charge of the subject

黒田直敬／Naotaka Kuroda

授業担当教員名（オムニバス科目等）／Professor(s)黒田直敬／Naotaka Kuroda, 岸川

科目分類／Class type

講義科目（区分Ｄ）, 特別コースの授業科目／NUPGP

対象年次／Year

1, 2

学期／Semester

教室／Class room
対象学生（クラス等）

曜日・校時／Day・Period

月／Mon 255031000

直哉／Kishikawa Naoya

直哉／Kishikawa Naoya

講義形態／Class Form

講義／Lecture〔薬学〕本館５階リフレッシュルーム／Pharmaceutical School 5th floor refresh room

/Object Student

Master course

担当教員Eメールアドレス/E‑mail addressn‑kuro@nagasaki‑u.ac.jp

担当教員研究室/Laboratory

Analytical Chemistry

担当教員TEL/Tel

095‑819‑2894

担当教員オフィスアワー/Office hours

Mon.〜Fri. 13:30‑17:00
Understanding of (1) the concepts and principles underlying the highly sensitive

授業の概要及び位置づけ/Course Outline anddetection techniques using luminescence, and (2) their typical application to biomedical
Objectives
and environmental analysis.
授業到達目標/Goal

1) Learn and understand the theories on which the principles of various analyticaltechniques are based, and2) become familiar with the important details of specific methods for biomedical

授業方法（学習指導法）/Method

For the lecture, audio‑visual equipments will be employed for a better understanding.

授業内容/Class outline/Con

Study of the fundamental principles of highly sensitive detection techniques forbiomedical and environmental analysis, and their applications.

キーワード/Key wordbiomedical analysis, luminescence, fluorescence, chemiluminescence

教科書・教材・参考書/Textbook,Teachingmaterial,and Reference book
成績評価の方法・基準等/Evaluation

Reference Book: Modern Derivatization Methods for Separation Sciences, Edited by T.
Toyo'oka, 1999, John Wiley & Sons Ltd.; Chemiluminescence in Analytical Chemistry,
Edited by A.M. Garcia‑Campana, W.R.G. Baeyens, 2001, Marcel Dekker Inc.
Your performance will be evaluated by active participation (30%) and reports (70%).
Students whose unexcused absences exceed 30% of the class will receive an automatic D forthe course.

受講要件（履修条件）/Requirements

アクセシビリティ/Accessibility

In order to ensure equal educational opportunities for all students, Nagasaki University
strives to remove societal barriers that may interfere with academic activities, and toprovide reasonable accommodations as necessary and appropriate. If you have any questions
or concerns regarding reasonable accommodations or other support in this class, pleasefeel free to talk to the instructor (contact information above), or contact the Student
Accessibility Office.
Student Accessibility Office contact information（TEL）095‑819‑2006（FAX）095‑819‑2948（E‑MAIL）support@ml.nagasaki‑u.ac.jp

備考（URL）/Remarks(URL)
学生へのメッセージ/Message for students
授業計画詳細／Course Schedule
回(日時)／Time(date and time)

授業内容／Contents

1stIntroduction to detection techniques based on luminescence for biomedical andenvironmental analysis (Kuroda)

2nd

Basics of luminescence (Kuroda)

3rdFluorescence in analytical chemistry (Kishikawa)

4th

Chemiluminescence and bioluminescence in analytical chemistry (Kuroda)

5thLatest technologies of luminescence in analytical chemistry

6thApplication of luminescence to biomedical and environmental analysis (1)3(Kishikawa)(Kishikawa)7thApplication of luminescence to biomedical and environmental analysis (2)8thGeneral overview and preparing of a report (Kuroda)

4(Ohyama)

開講期間／Class period

2016年度／Academic Year 前期／First Semester
2016/04/01 ~ 2016/09/27

必修選択／Required/Elective class

選択／elective

単位数(一般/編入/留学)／Credits
1.0(general/admission/overseas)

時間割コード／Time schedule code

20165503120008

科目番号／Subject code

科目ナンバリングコード／Numbering Code

BMMP51332781

授業科目名／Subject

Bioorganic Chemistry I／Bioorganic Chemistry for Environmental Science I

編集担当教員／Professor in charge ofputting together the course syllabus

田中

正一／Tanaka Masakazu, 大庭

授業担当教員名（科目責任者）／Professor in charge of the subject

田中

正一／Tanaka Masakazu

授業担当教員名（オムニバス科目等）／Professor(s)田中

正一／Tanaka Masakazu, 大庭

科目分類／Class type

講義科目（区分Ｄ）, 特別コースの授業科目／NUPGP

対象年次／Year

1, 2

学期／Semester

教室／Class room
対象学生（クラス等）

曜日・校時／Day・Period

火／Tue 355031200

誠／Oba Makoto, 上田

篤志／Ueda Atsushi

誠／Oba Makoto, 上田

篤志／Ueda Atsushi

講義形態／Class Form

講義／Lecture〔薬学〕本館３階セミナー室／Pharmaceutical School 3rd floor seminar room

/Object Student

Master course

担当教員Eメールアドレス/E‑mail addressmatanaka@ nagasaki‑u.ac.jp

担当教員研究室/Laboratory

Pharmaceutical Chemistry

担当教員TEL/Tel

095‑819‑2423

Tuesday 16:00‑18:00
担当教員オフィスアワー/Office hours
授業の概要及び位置づけ/Course Outline and To provide the students with fundamental knowledge of 3D structures, bioorganic
molecules, including asymmetric reactions, and polymer chemistries.
Objectives

授業到達目標/Goal

To understand how the three‑dimensional structures of organic molecules can besynthesized, and also how the polymer chemistry can be applied to medicine.

授業方法（学習指導法）/Method

Lecture using PowerPoint slides and printed documents.

授業内容/Class outline/Con

This course will first cover the three‑dimensional structures of small molecules as
bioorganic molecules and deal with the activities of stereoisomers. Then, the course
will cover the basic of stereoselective synthesis of enantiomers and diastereomers.
Furthermore, the course will cover the polymer chemistry and their application to
medicine, especially in gel and regenerative medicine.

キーワード/Key word
教科書・教材・参考書/Textbook,Teachingmaterial,and Reference book
成績評価の方法・基準等/Evaluation

3D structure, stereochemistry, catalysis, polymer chemistry
Printed documents
Contribution in group discussion (50%), and completion of assignments (50%)

受講要件（履修条件）/Requirements

アクセシビリティ/Accessibility

In order to ensure equal educational opportunities for all students, Nagasaki University
strives to remove societal barriers that may interfere with academic activities, and toprovide reasonable accommodations as necessary and appropriate. If you have any questions
or concerns regarding reasonable accommodations or other support in this class, pleasefeel free to talk to the instructor (contact information above), or contact the Student
Accessibility Office.
Student Accessibility Office contact information（TEL）095‑819‑2006（FAX）095‑819‑2948（E‑MAIL）support@ml.nagasaki‑u.ac.jp

備考（URL）/Remarks(URL)
学生へのメッセージ/Message for students

The three‑dimensional structures
drug design.

of molecules and polymer chemistry are important for

授業計画詳細／Course Schedule
回(日時)／Time(date and time)

授業内容／Contents

1st

Activities of stereoisomers [M. Tanaka]

2ndBasic of stereochemistry [M. Tanaka]

3rd

Enantioselective reaction [M. Tanaka]

4th

Diastereoselective reaction [M. Tanaka]

5th

Example of asymmetric reactions [M. Tanaka]

6thPolymer chemistry [Oba]7thApplication of polymer chemistry ‑Gel‑ [Oba]

5

8th

Stereoselective synthesis of marine natural products and their application to drug
development [Ueda]

6

開講期間／Class period

2016年度／Academic Year 前期／First Semester
2016/04/01 ~ 2016/09/27

必修選択／Required/Elective class

選択／elective

単位数(一般/編入/留学)／Credits
1.0(general/admission/overseas)

時間割コード／Time schedule code

20165503173109

科目番号／Subject code

科目ナンバリングコード／Numbering Code

BMMP51232784

授業科目名／Subject

Pharmacology and Drug Discovery I／Pharmacology and Drug Discovery I

編集担当教員／Professor in charge ofputting together the course syllabus

植田

弘師／Ueda Hiroshi, 塚原

授業担当教員名（科目責任者）／Professor in charge of the subject

植田弘師／Ueda Hiroshi

授業担当教員名（オムニバス科目等）／Professor(s)植田

弘師／Ueda Hiroshi, 塚原

科目分類／Class type

特別コースの授業科目／NUPGP

対象年次／Year

1, 2

学期／Semester

教室／Class room
対象学生（クラス等）

曜日・校時／Day・Period

水／Wed 255031731

完／Tsukahara Tamotsu

完／Tsukahara Tamotsu

講義形態／Class Form

講義／Lecture〔薬学〕本館４階セミナー室／Pharmaceutical School 4th floor seminar room

/Object Student

Master course

担当教員Eメールアドレス/E‑mail address

ueda@nagasaki‑u.ac.jp
ttamotsu@nagasaki‑u.ac.jp

担当教員研究室/Laboratory

Pharmacology and Therapeutic Innovation

担当教員TEL/Tel

095‑819‑2421, 2473

担当教員オフィスアワー/Office hours

Accept any question by e‑mailTo teach the mechanism of acute and chronic pain

授業の概要及び位置づけ/Course Outline and/ To teach the new approaches of drug discovery
Objectives
against some topics
授業到達目標/Goal

To understand and to be able to summarize the mechanisms underlying pain and thetherapeutic innovation in drug discovery

授業方法（学習指導法）/Method

Lecture using power‑point slides and printed documents

授業内容/Class outline/Con

キーワード/Key word
教科書・教材・参考書/Textbook,Teachingmaterial,and Reference book
成績評価の方法・基準等/Evaluation

Pain and opioid actions are an important topic in terms of social issues and basic
science. The study of mechanisms underlying development of chronic pain, such as cancer
pain, and opioid tolerance following chronic treatments leads to a better understandingof neuronal plasticity, which is one of most important topics in neuroscience as well as
memory and learning.
The scope of therapeutic innovation reaches beyond the focus of pharmaceuticals, and its
research and development, to include innovations in drugs, devices, and diagnostics, aswell as global regulatory issues.

Chronic pain, Stroke, Infectious disease, Cancer, Medicinal chemistry

Active commitment (50%) to the lecture and examination (50%) on each topic

受講要件（履修条件）/Requirements

アクセシビリティ/Accessibility

In order to ensure equal educational opportunities for all students, Nagasaki University
strives to remove societal barriers that may interfere with academic activities, and toprovide reasonable accommodations as necessary and appropriate. If you have any questions
or concerns regarding reasonable accommodations or other support in this class, pleasefeel free to talk to the instructor (contact information above), or contact the Student
Accessibility Office.
Student Accessibility Office contact information（TEL）095‑819‑2006（FAX）095‑819‑2948（E‑MAIL）support@ml.nagasaki‑u.ac.jp

備考（URL）/Remarks(URL)
学生へのメッセージ/Message for students
授業計画詳細／Course Schedule
回(日時)／Time(date and time)

授業内容／Contents

1st

Mechanisms of acute and chronic pain (Ueda)

2nd

Epigenomic regulation of chronic pain‑related genes (Ueda)

7

3rd

Lipid mediators as key molecules for chronic pain (Ueda)

4th

Recent topics on neurogenesis (Ueda)

5th

New approaches for the drug discovery against stroke (Tsukahara)

6th

New approaches for the drug discovery against infectious diseases (Tsukahara)

7th

New approaches for the drug discovery against cancer (Tsukahara)

8thIntroduction of medicinal chemistry (Tsukahara)

8

開講期間／Class period

2016年度／Academic Year 前期／First Semester
2016/04/01 ~ 2016/09/27

必修選択／Required/Elective class

選択／elective

単位数(一般/編入/留学)／Credits
1.0(general/admission/overseas)

時間割コード／Time schedule code

20165503160012

科目番号／Subject code

科目ナンバリングコード／Numbering Code

BMMP52132785

授業科目名／Subject

Natural Product Chemistry I／Natural Product Chemistry for Infectious Diseases I

編集担当教員／Professor in charge ofputting together the course syllabus

田中隆／Tanaka Takashi, 松尾

授業担当教員名（科目責任者）／Professor in charge of the subject

田中隆／Tanaka Takashi

授業担当教員名（オムニバス科目等）／Professor(s)田中隆／Tanaka Takashi, 松尾

科目分類／Class type

講義科目（区分Ｄ）, 特別コースの授業科目／NUPGP

対象年次／Year

1, 2

学期／Semester

教室／Class room
対象学生（クラス等）

曜日・校時／Day・Period

金／Fri 255031600

洋介／Matsuo Yosuke, 齋藤義紀／Saito Yoshinori

洋介／Matsuo Yosuke, 齋藤義紀／Saito Yoshinori

講義形態／Class Form

講義／Lecture〔薬学〕本館３階セミナー室／Pharmaceutical School 3rd floor seminar room

/Object Student

Master course

担当教員Eメールアドレス/E‑mail address

Takashi Tanaka / t‑tanaka@nagasaki‑u.ac.jp

担当教員研究室/Laboratory

Natural Product Chemistry

担当教員TEL/Tel2432

担当教員オフィスアワー/Office hours

Any time (Please make appointment by E‑mail ）The aim of the lecture is to understand classification of natural products by their

授業の概要及び位置づけ/Course Outline andbiosynthesis pathway. In addition, methods used for separation, structure elucidation,
Objectives
and application to functional materials will be introduced.

授業到達目標/Goal

1) Acquire knowledge of the classification the natural products by their molecular
structures andbiosynthesis.
2) Aqcuire knowledge of the functions of important natural products and theirapplication.

授業方法（学習指導法）/Method

Lecture (with Power Point presentation)

授業内容/Class outline/Con

Natural organic compounds produced by plants and microorganisms are important source of
medicines. Many modern medicines are originated from seed compounds isolated from living
things, and many crude drugs, such as herbs and traditional medicines, are still widelyused in contemporary medicine. This class aimed to understand the chemistry of natural
products and techniques used for separation and identification of compounds..

キーワード/Key word
教科書・教材・参考書/Textbook,Teachingmaterial,and Reference book
成績評価の方法・基準等/Evaluation

Biosynthesis, structure determination, chromatography, NMR

受講要件（履修条件）/Requirements

None

アクセシビリティ/Accessibility

No text book, Reference: Medicinal Natural Products (Dewick)report(20%), exercise(80%)
In order to ensure equal educational opportunities for all students, Nagasaki University
strives to remove societal barriers that may interfere with academic activities, and toprovide reasonable accommodations as necessary and appropriate. If you have any questions
or concerns regarding reasonable accommodations or other support in this class, pleasefeel free to talk to the instructor (contact information above), or contact the Student
Accessibility Office.
Student Accessibility Office contact information（TEL）095‑819‑2006（FAX）095‑819‑2948（E‑MAIL）support@ml.nagasaki‑u.ac.jp

備考（URL）/Remarks(URL)

http://www.ph.nagasaki‑u.ac.jp/lab/natpro/index‑j.html

学生へのメッセージ/Message for students

None

授業計画詳細／Course Schedule
回(日時)／Time(date and time)

授業内容／Contents

1

Biosynthetic pathway for Natural compounds (1)2Biosynthetic pathway for Natural compounds (2)3

Separation of Natural Products and structure determination by spectroscopic and chemical
method (1)94Separation of Natural Products and structure determination by spectroscopic and chemical
method (2)5Plant polyphenols and application to functional foods

6

Biomimetic reactions of plant polyphenols

7

Chemistry of color

8

Physicochemical properties of tannins and chemical ecology

10開講期間／Class period

2016年度／Academic Year 前期／First Semester
2016/04/01 ~ 2016/09/27

必修選択／Required/Elective class

選択／elective

単位数(一般/編入/留学)／Credits
1.0(general/admission/overseas)

時間割コード／Time schedule code

20165503151011

科目番号／Subject code

科目ナンバリングコード／Numbering Code

BMMP55142783

授業科目名／Subject

Molecular Biology of Infectious AgentsⅡ／Molecular Biology of Infectious Agents Ⅱ

編集担当教員／Professor in charge ofputting together the course syllabus

北里

海雄／Kitazato Kaio

授業担当教員名（科目責任者）／Professor in charge of the subject

北里

海雄／Kitazato Kaio

授業担当教員名（オムニバス科目等）／Professor(s)北里

海雄／Kitazato Kaio

科目分類／Class type

講義科目（区分Ｄ）, 特別コースの授業科目／NUPGP

対象年次／Year

1, 2

学期／Semester

教室／Class room
対象学生（クラス等）

曜日・校時／Day・Period

講義形態／Class Form

金／Fri 255031510

講義／Lecture〔薬学〕本館２階セミナー室／Pharmaceutical School 2nd floor seminar room

/Object Student

Master course

担当教員Eメールアドレス/E‑mail address

kkholi@nagasaki‑u.ac.jp

担当教員研究室/Laboratory

Lab of Molecular Pharmacology of infectious agents

担当教員TEL/Tel

095‑819‑2457

Email anytime is OK, meeting time 5：00‑6：00pm
担当教員オフィスアワー/Office hours
授業の概要及び位置づけ/Course Outline and Aim: To teach the topics of emerging infectious diseases
Objectives

授業到達目標/Goal

Goal: To understand and to be able to summarize the emerging infectious diseases andcurrent antiviral therapy for viral diseases.

授業方法（学習指導法）/Method

Method: Lecture and seminar using PowerPoint slides or printed documents

授業内容/Class outline/Con

Class outline/
Emerging infectious diseases are an important topics in terms of social issues andscience. The study of replication of infectious agents and their interaction with hostfactors leads to a better understanding of infectious diseases and to help to develop new
drugs of anti‑infectious agents.

キーワード/Key word
教科書・教材・参考書/Textbook,Teachingmaterial,and Reference book
成績評価の方法・基準等/Evaluation

virus diseases, antivirals, vaccine development

受講要件（履修条件）/Requirements

Method of achievement evaluation/ attendance (50%) and report (50%)

アクセシビリティ/Accessibility

In order to ensure equal educational opportunities for all students, Nagasaki University
strives to remove societal barriers that may interfere with academic activities, and toprovide reasonable accommodations as necessary and appropriate. If you have any questions
or concerns regarding reasonable accommodations or other support in this class, pleasefeel free to talk to the instructor (contact information above), or contact the Student
Accessibility Office.
Student Accessibility Office contact information（TEL）095‑819‑2006（FAX）095‑819‑2948

Articles and reviews for virus diseases from top journals

備考（URL）/Remarks(URL)
学生へのメッセージ/Message for students
授業計画詳細／Course Schedule
回(日時)／Time(date and time)

授業内容／Contents

1

1. Introduction to virus diseases

2
3

Current topics in emerging virus diseases I
Current topics in emerging virus diseases II

4

Current topics in emerging virus diseases III

5

Antiviral strategies.

6

Antiviral drug development

7

Vaccine development

8

Perspective in viral therapy

11

開講期間／Class period

2016年度／Academic Year 後期／Second Semester
2016/09/28 ~ 2017/03/31

必修選択／Required/Elective class

選択／elective

単位数(一般/編入/留学)／Credits
1.0(general/admission/overseas)

時間割コード／Time schedule code

20165503141007

科目番号／Subject code

科目ナンバリングコード／Numbering Code

BMMP53242787

授業科目名／Subject

Inorganic Chemistry Ⅱ／Inorganic Chemistry in Health and Environmental Sciences Ⅱ

編集担当教員／Professor in charge ofputting together the course syllabus

中山
大山守雄／Nakayama Morio, 淵上 剛志／Fuchigami Takeshi, 麓
要／Ohyama Kaname, 西田 孝洋／Nishida Koyo

授業担当教員名（科目責任者）／Professor in charge of the subject

中山守雄／Nakayama Morio

授業担当教員名（オムニバス科目等）／Professor(s)中山大山守雄／Nakayama Morio, 淵上 剛志／Fuchigami Takeshi, 麓
要／Ohyama Kaname, 西田 孝洋／Nishida Koyo

科目分類／Class type

講義科目（区分Ｄ）, 特別コースの授業科目／NUPGP

対象年次／Year

1, 2

学期／Semester

教室／Class room
対象学生（クラス等）

曜日・校時／Day・Period

講義形態／Class Form

火／Tue 355031410

伸太郎／Fumoto Shintaro,

伸太郎／Fumoto Shintaro,

講義／Lecture〔薬学〕本館５階リフレッシュルーム／Pharmaceutical School 5th floor refresh room

/Object Student

Master course

担当教員Eメールアドレス/E‑mail address

morio@nagasaki‑u.ac.jp

担当教員研究室/Laboratory

Hygienic Chemistry

担当教員TEL/Tel

095‑819‑2441

担当教員オフィスアワー/Office hours

Monday−Friday 0:20−0:50 p.m. or by appointment
The aims of this subject are a) to be aware of what metal and metalloid elements are

授業の概要及び位置づけ/Course Outline andimportant in biology and medicine, and b) to give you state‑of‑the‑art knowledge of the
Objectives
biological inorganic chemistry and nuclear medicine.

授業到達目標/Goal

The goals of this subject are a) a broad understanding of metal and metalloid elements inbiological systems and medicine, b) to understand what essential trace elements are andexplain the biological functions of essential trace elements with showing an example, andc) to understand what radiopharmaceuticals are and explain one of their applications inmedicine.

授業方法（学習指導法）/Method

PowerPoint slides, Video, Printed matters (Scientific magazines, Newspapers, etc)

授業内容/Class outline/Con

This is an advanced class on biological inorganic chemistry with emphasis to biologicallyimportant and medically useful metal and metalloid elements. Issues of particularinterest are biological functions of essential trace elements, such as iron, zinc,cupper, selenium, etc., and the concept of metal‑containing radiopharmaceuticals fordiagnosis. This lecture is not intended to describe or explain everything you will learn
in the biological inorganic chemistry; rather, it will indicate important topics to study
and will give you an opportunity to think about these topics.

キーワード/Key word
教科書・教材・参考書/Textbook,Teachingmaterial,and Reference book

Metal, Metalloid, Essential element, Radiopharmaceutical, Nuclear Medicine, Diagnosis,
Textbook, Teaching Material, and Reference Book / Textbook and reference materials are
not specified.

成績評価の方法・基準等/Evaluation

Grading will be based on midterm and/or final exam (80%) and report (20%). (NOTICE : On‑time regular attendance is required throughout the class.)

受講要件（履修条件）/Requirements

Nothing

アクセシビリティ/Accessibility

In order to ensure equal educational opportunities for all students, Nagasaki University
strives to remove societal barriers that may interfere with academic activities, and toprovide reasonable accommodations as necessary and appropriate. If you have any questions
or concerns regarding reasonable accommodations or other support in this class, pleasefeel free to talk to the instructor (contact information above), or contact the Student
Accessibility Office.
Student Accessibility Office contact information（TEL）095‑819‑2006（FAX）095‑819‑2948（E‑MAIL）support@ml.nagasaki‑u.ac.jp

備考（URL）/Remarks(URL)
学生へのメッセージ/Message for students

Basically, the instructors will give handout s of selected PowerPoint slides to be usedin each lecture out to the attendees.

授業計画詳細／Course Schedule
回(日時)／Time(date and time)

授業内容／Contents

1stOverview: Metal and Metalloid Elements in Biology, Medicine and Environment (Nakayama)

2ndRadiopharmaceuticals in Nuclear Medicine (I) (Nakayama)

12

3rd

Radiopharmaceuticals in Nuclear Medicine (II) (Fuchigami)

4thProteomic Analysis in

Animal Model and Human I (Ohyama)

5thProteomic Analysis in

Animal Model and Human I (Ohyama)

6th

Drug Delivery Systems (Nishida and Fumoto)

7th

Drug Delivery Systems (Nishida and Fumoto)

8th

Review

13

開講期間／Class period

2016年度／Academic Year 後期／Second Semester
2016/09/28 ~ 2017/03/31

必修選択／Required/Elective class

選択／elective

単位数(一般/編入/留学)／Credits
1.0(general/admission/overseas)

時間割コード／Time schedule code

20165503191003

科目番号／Subject code

科目ナンバリングコード／Numbering Code

BMMP51542781

授業科目名／Subject

Synthesis of Drugs Ⅱ／Synthesis of Drugs for Infectious Diseases Ⅱ

編集担当教員／Professor in charge ofputting together the course syllabus

尾野村治／Onomura Osamu, 栗山

授業担当教員名（科目責任者）／Professor in charge of the subject

尾野村治／Onomura Osamu

授業担当教員名（オムニバス科目等）／Professor(s)尾野村治／Onomura Osamu, 栗山

科目分類／Class type

講義科目（区分Ｄ）, 特別コースの授業科目／NUPGP

対象年次／Year

1, 2

学期／Semester

教室／Class room
対象学生（クラス等）

曜日・校時／Day・Period

水／Wed 355031910

正巳／Kuriyama Masami

正巳／Kuriyama Masami

講義形態／Class Form

講義／Lecture〔薬学〕本館３階セミナー室／Pharmaceutical School 3rd floor seminar room

/Object Student

Master course

担当教員Eメールアドレス/E‑mail address

onomura@nagasaki‑u.ac.jp

担当教員研究室/Laboratory

Synthetic Chemistry for Pharmaceuticals

担当教員TEL/Tel

095‑819‑2429

担当教員オフィスアワー/Office hours

Mon. ‑ Fri. 10:30 ‑ 18:00
You learn systematically selective reactions which synthesize complicated organic

授業の概要及び位置づけ/Course Outline and molecules and are necessary for development of new drugs for infectious diseases.
Professional education
Objectives

授業到達目標/Goal

授業方法（学習指導法）/Method

授業内容/Class outline/Con(1) You can explain representative asymmetric reactions.
(2) You can get practical knowledge necessary for invention of new drugs.
Lectures concerning about development of new synthetic methods, which are extracted fromnew literatures and patents, are given by utilizing prints and slide‑projector. Exercises
are timely carried out.
You can learn highly selective reactions for development of new drugs, for examples,
selective organic synthesis utilizing the characteristics of nitrogen, synthesis of
optically active cyclic amino compounds, and so on.

キーワード/Key word
教科書・教材・参考書/Textbook,Teachingmaterial,and Reference book
成績評価の方法・基準等/EvaluationNone

受講要件（履修条件）/Requirements

None

アクセシビリティ/Accessibility

Documents prepared from recent literatures are distributed.
Exercise (30%), Test (30%), Report (40%)
In order to ensure equal educational opportunities for all students, Nagasaki University
strives to remove societal barriers that may interfere with academic activities, and toprovide reasonable accommodations as necessary and appropriate. If you have any questions
or concerns regarding reasonable accommodations or other support in this class, pleasefeel free to talk to the instructor (contact information above), or contact the Student
Accessibility Office.
Student Accessibility Office contact information（TEL）095‑819‑2006（FAX）095‑819‑2948（E‑MAIL）support@ml.nagasaki‑u.ac.jp

備考（URL）/Remarks(URL)
学生へのメッセージ/Message for students

In advance, master basic knowledge of organic chemistry.

授業計画詳細／Course Schedule
回(日時)／Time(date and time)

授業内容／Contents

1

Selective organic synthesis utilizing the characteristics of nitrogen I (Onomura)2

Selective organic synthesis utilizing the characteristics of nitrogen II (Onomura)

3

Selective organic synthesis utilizing the characteristics of nitrogen III (Onomura)

4

Synthesis of optically active cyclic amino compounds (Onomura)

5

Selective organic synthesis utilizing the characteristics of silicon (Kuriyama)

14

6

Selective organic synthesis utilizing the characteristics of borone (Kuriyama)

7

Selective organic synthesis utilizing the characteristics of fluorine (Kuriyama)

8

Synthesis of sugars (Kuriyama)15

開講期間／Class period

2016年度／Academic Year 後期／Second Semester
2016/09/28 ~ 2017/03/31

必修選択／Required/Elective class

選択／elective

単位数(一般/編入/留学)／Credits
1.0(general/admission/overseas)

時間割コード／Time schedule code

20165503131001

科目番号／Subject code

科目ナンバリングコード／Numbering Code

BMMP51142783

授業科目名／Subject

Cell Biology for Health Science Ⅱ／Cell Biology for Health Science Ⅱ

編集担当教員／Professor in charge ofputting together the course syllabus

武田弘資／Takeda Kohsuke, 谷村

授業担当教員名（科目責任者）／Professor in charge of the subject

武田弘資／Takeda Kohsuke

授業担当教員名（オムニバス科目等）／Professor(s)武田弘資／Takeda Kohsuke, 谷村

科目分類／Class type

講義科目（区分Ｄ）, 特別コースの授業科目／NUPGP

対象年次／Year

1, 2

学期／Semester

教室／Class room
対象学生（クラス等）

曜日・校時／Day・Period

木／Thu 255031310

進／Tanimura Susumu

進／Tanimura Susumu

講義形態／Class Form

講義／Lecture〔薬学〕本館４階セミナー室／Pharmaceutical School 4th floor seminar room

/Object Student

Master course

担当教員Eメールアドレス/E‑mail address

takeda‑k@nagasaki‑u.ac.jp

担当教員研究室/Laboratory

Cell Regulation

担当教員TEL/Tel

095‑819‑2417

At any time by e‑mail担当教員オフィスアワー/Office hours
授業の概要及び位置づけ/Course Outline and To learn the mechanisms and significance of intracellular signal transduction regulating
various cellular functions.
Objectives

授業到達目標/Goal

To undestand the mechanisms of intracellular signal transduction and their dysregulationin various diseases.

授業方法（学習指導法）/Method

Lecture using PowerPoint slides and printed documents.

授業内容/Class outline/Con
キーワード/Key word
教科書・教材・参考書/Textbook,Teachingmaterial,and Reference book
成績評価の方法・基準等/Evaluation
受講要件（履修条件）/Requirements

アクセシビリティ/Accessibility

Regarding the following respective topics, latest research achievements and perspectives,
as well as basic findings, will be provided.
signal transduction, cell motility, stress response, cancer, inflammation, metabolism,mitochondria
Reference book: Molecular Biology of the Cell 5th Edition
Attendance (40%), Report (60%)
Those who take this class must have fundamental knowledge on cell biology and molecularbiology.
In order to ensure equal educational opportunities for all students, Nagasaki University
strives to remove societal barriers that may interfere with academic activities, and toprovide reasonable accommodations as necessary and appropriate. If you have any questions
or concerns regarding reasonable accommodations or other support in this class, pleasefeel free to talk to the instructor (contact information above), or contact the Student
Accessibility Office.
Student Accessibility Office contact information（TEL）095‑819‑2006（FAX）095‑819‑2948（E‑MAIL）support@ml.nagasaki‑u.ac.jp

備考（URL）/Remarks(URL)
学生へのメッセージ/Message for students
授業計画詳細／Course Schedule
回(日時)／Time(date and time)

授業内容／Contents

1st: Oct 6

Overview [Takeda]

2nd: Oct 13

Mechanisms of signal transduction‑1 [Takeda]

3rd: Oct 20

Mechanisms of signal transduction‑2

4th: Oct 27

Dysregulation of the ubiquitin system and diseases [Takeda]

5th: Nov 10

Cell cycle regulation via protein phosphorylation and dephosphorylation (1) [Takeda]

6th: Nov 17

Cell cycle regulation via protein phosphorylation and dephosphorylation (2) [Takeda]

7th: Nov 24

Dysregulation of environmental stress response and diseases [Takeda]

8th: Dec 1

Regulation of cell motility [Tanimura]

16[Takeda]開講期間／Class period

2016年度／Academic Year 後期／Second Semester
2016/09/28 ~ 2017/03/31

必修選択／Required/Elective class

選択／elective

単位数(一般/編入/留学)／Credits
1.0(general/admission/overseas)

時間割コード／Time schedule code

20165503133006

科目番号／Subject code

科目ナンバリングコード／Numbering Code

BMMP53142782

授業科目名／Subject

Chemistry of Biofunctional Molecules Ⅱ／Chemistry of Biofunctional Molecules for
Infectious Diseases Ⅱ

編集担当教員／Professor in charge ofputting together the course syllabus

甲斐雅亮／Kai Masaaki, 椛島

授業担当教員名（科目責任者）／Professor in charge of the subject

甲斐雅亮／Kai Masaaki

授業担当教員名（オムニバス科目等）／Professor(s)甲斐雅亮／Kai Masaaki, 椛島

科目分類／Class type

講義科目（区分Ｄ）, 特別コースの授業科目／NUPGP

対象年次／Year

1, 2

学期／Semester

教室／Class room
対象学生（クラス等）

曜日・校時／Day・Period

木／Thu 255031330

力／Kabashima Tsutomu, 柴田

孝之／Shibata Takayuki

力／Kabashima Tsutomu, 柴田

孝之／Shibata Takayuki

講義形態／Class Form

講義／Lecture〔薬学〕本館４階セミナー室／Pharmaceutical School 4th floor seminar room

/Object Student

Master course

担当教員Eメールアドレス/E‑mail address

ms‑kai@nagasaki‑u.ac.jp

担当教員研究室/Laboratory

Chemistry of Biofunctional Molecules

担当教員TEL/Tel

095‑819‑2438

12:00‑18:00
担当教員オフィスアワー/Office hours
授業の概要及び位置づけ/Course Outline and To study and discuss about scientific technology for functional analysis of proteins andnucleic acids.
Objectives

授業到達目標/Goal

To understand about scientific technology for functional analysis of proteins and nucleic
acids.

授業方法（学習指導法）/Method

Presentation and discussion using printed matters, computer slides and scientificStudy on analytical technology and bio‑function of biogenetic macromolecules.

授業内容/Class outline/Con

キーワード/Key word
教科書・教材・参考書/Textbook,Teachingmaterial,and Reference book
成績評価の方法・基準等/Evaluation

1. Functional outline and techniques of biogenic macromolecules
2. Protein‑protein interaction and its analysis (1)3. Protein‑protein interaction and its analysis (2)4. Nucleic acid‑nucleic acid interaction and its analysis (1)5. Nucleic acid‑nucleic acid interaction and its analysis (2)6. Protein‑nucleic acid interaction and its analysis (1)7. Protein‑nucleic acid interaction and its analysis (2)8. Discussion of lecture
Proteins, Nucleic acids
Scientific journals, Printed matters
Report (50%), Aggressiveness (50%)

受講要件（履修条件）/Requirements

アクセシビリティ/Accessibility

In order to ensure equal educational opportunities for all students, Nagasaki University
strives to remove societal barriers that may interfere with academic activities, and toprovide reasonable accommodations as necessary and appropriate. If you have any questions
or concerns regarding reasonable accommodations or other support in this class, pleasefeel free to talk to the instructor (contact information above), or contact the Student
Accessibility Office.
Student Accessibility Office contact information（TEL）095‑819‑2006（FAX）095‑819‑2948（E‑MAIL）support@ml.nagasaki‑u.ac.jp

備考（URL）/Remarks(URL)
学生へのメッセージ/Message for students

17

開講期間／Class period

2016年度／Academic Year
後期／Second Semester
2016/09/28 ~ 2017/03/31

必修選択／Required/Elective class

選択／elective

単位数(一般/編入/留学)／Credits
1.0(general/admission/overseas)

時間割コード／Time schedule code

20165503171002

科目番号／Subject code

科目ナンバリングコード／Numbering Code

BMMP51442781

授業科目名／Subject

Pharmaceutical Organic Chemistry Ⅱ／Pharmaceutical Organic Chemistry for Infectious
Diseases Ⅱ

編集担当教員／Professor in charge ofputting together the course syllabus

石原淳(大学院大学院医歯薬学総合研究科（薬系）)

授業担当教員名（科目責任者）／Professor in charge of the subject

石原淳(大学院大学院医歯薬学総合研究科（薬系）)

授業担当教員名（オムニバス科目等）／Professor(s)石原淳(大学院大学院医歯薬学総合研究科（薬系）)

科目分類／Class type

講義科目（区分Ｄ）, 特別コースの授業科目／NUPGP

対象年次／Year

1年,2年

学期／Semester

教室／Class room
対象学生（クラス等）

曜日・校時／Day・Period

講義形態／Class Form

金/Fri

2

55031710

講義／Lecture［薬学］3F第１セミナー室／Pharmaceutical School 3rd floor seminar room

/Object Student

担当教員Eメールアドレス/E‑mail address

Master course
jishi@nagasaki‑u.ac.jp

担当教員研究室/Laboratory
担当教員TEL/Tel

095‑819‑2427

担当教員オフィスアワー/Office hours

Mon.‑Fri. 13:00‑18:00
The synthesis of natural products is a very important research field of drug discovery.

授業の概要及び位置づけ/Course Outline andIn this class, the students will learn the synthesis of natural products possess useful
Objectives
biological activities for developing drugs for the treatment of infectious diseases.
授業到達目標/Goal

1) An understanding of synthetic plans and strategies.
2) An understanding of synthetic reactions.
3) An understanding of synthetic routes.

授業方法（学習指導法）/Method

Lecture using Power Point slides and printed documents.

授業内容/Class outline/Con

This class provides several representative drug candidates for the infectious deseases as
examples in order for the students to understand how to

キーワード/Key word
教科書・教材・参考書/Textbook,Teachingmaterial,and Reference book
成績評価の方法・基準等/Evaluation

Journals (JACS, JOC, OL, TL, Angew. Chem. Int. Ed., Chem. Commun, etc.)
enthusiastic attitude (30%) and report (70%)

受講要件（履修条件）/Requirements

アクセシビリティ/Accessibility

In order to ensure equal educational opportunities for all students, Nagasaki University
strives to remove societal barriers that may interfere with academic activities, and toprovide reasonable accommodations as necessary and appropriate. If you have any questions
or concerns regarding reasonable accommodations or other support in this class, pleasefeel free to talk to the instructor (contact information above), or contact the Student
Accessibility Office.
Student Accessibility Office contact information（TEL）095‑819‑2006（FAX）095‑819‑2948（E‑MAIL）support@ml.nagasaki‑u.ac.jp

備考（URL）/Remarks(URL)
学生へのメッセージ/Message for students
授業計画詳細／Course Schedule
回(日時)／Time(date and time)

授業内容／Contents

1stDrug candidates and their syntheses (Ishihara)

2nd

Drug candidates and their syntheses (Ishihara)

3rd

Drug candidates and their syntheses (Ishihara)

4th

Drug candidates and their syntheses (Ishihara)

5thDrug candidates and their syntheses (Ishihara)

6th

Drug candidates and their syntheses (Ishihara)

7th

Drug candidates and their syntheses (Ishihara)

8th

Drug candidates and their syntheses (Ishihara)

18

開講期間／Class period

2016年度／Academic Year 後期／Second Semester
2016/09/28 ~ 2017/03/31

必修選択／Required/Elective class

選択／elective

単位数(一般/編入/留学)／Credits
0.5(general/admission/overseas)

時間割コード／Time schedule code

20165503180004

科目番号／Subject code

科目ナンバリングコード／Numbering Code

BMMP52222785

授業科目名／Subject

Resources of Marine Natural Medicines／Resources of Marine Natural Medicines for
Infectious Diseases

編集担当教員／Professor in charge ofputting together the course syllabus

山田

耕史／Yamada Koji

授業担当教員名（科目責任者）／Professor in charge of the subject

山田

耕史／Yamada Koji

授業担当教員名（オムニバス科目等）／Professor(s)山田

耕史／Yamada Koji

科目分類／Class type

講義科目（区分Ｄ）, 特別コースの授業科目／NUPGP

対象年次／Year

1, 2

学期／Semester

教室／Class room
対象学生（クラス等）

曜日・校時／Day・Period

講義形態／Class Form

金／Fri 255031800

講義／Lecture

薬用植物園２階セミナー室／Medical Plants Garden 2nd floor seminar room

/Object Student

Master course

担当教員Eメールアドレス/E‑mail address

kyamada@nagasaki‑u.ac.jp

担当教員研究室/Laboratory

Medicinal Plant Biochemistry

担当教員TEL/Tel

095‑819‑2462

Monday 13:00‑14:00
担当教員オフィスアワー/Office hours
授業の概要及び位置づけ/Course Outline andTo teach the marine natural medicines for infectious diseases
Objectives
To understand and to be able to summarize underlying marine natural medicines
授業到達目標/Goal

授業方法（学習指導法）/Method

授業内容/Class outline/Con

Lecture using power point slides and printed documents
he marine environment has proven to be a very rich source of extremely potent compounds
that have demonstrated significant activities in antimicrobial, antitumor, anti‑
inflammatory, analgesia, immunomodulation, allergy, and anti‑viral assay. There are now
significant numbers of very interesting molecules that have come from marine sources, or
have been synthesized as a result of knowledge gained from a prototypical compounds, thatare either in or approaching Phase II/III clinical trials in infectious, cancer,
analgesia, allergy, and cognitive diseases. A substantial number of other potential
agents are following in their wake in preclinical trials in these and in other diseases.
In this lecture, it introduces mainly the latest research on the marine organism, andthey are reviewed from the aspect of the medicine resource.

キーワード/Key word

Marine Natural Products, antimicrobial, antitumor, anti‑inflammatory, analgesia,
immunomodulation, allergy, anti‑viral, antiplasmodial agents

教科書・教材・参考書/Textbook,Teachingmaterial,and Reference booknone

成績評価の方法・基準等/Evaluation

The achievement level of the above‑mentioned target is evaluated by following standards.
Report (80%) and Approach attitude to the problem of class (20%)

受講要件（履修条件）/Requirements

It is desirable to have learned the foundation of organic chemistry.

アクセシビリティ/Accessibility

In order to ensure equal educational opportunities for all students, Nagasaki University
strives to remove societal barriers that may interfere with academic activities, and toprovide reasonable accommodations as necessary and appropriate. If you have any questions
or concerns regarding reasonable accommodations or other support in this class, pleasefeel free to talk to the instructor (contact information above), or contact the Student
Accessibility Office.
Student Accessibility Office contact information（TEL）095‑819‑2006（FAX）095‑819‑2948（E‑MAIL）support@ml.nagasaki‑u.ac.jp

備考（URL）/Remarks(URL)
学生へのメッセージ/Message for students

Since this lecture is based on marine natural products chemistry, to often review isrequired. The newest literature of a related field is read.

授業計画詳細／Course Schedule
回(日時)／Time(date and time)

授業内容／Contents

19

1

The possibilities of marine organisms for the medicinal sources (Yamada)

2

Materials for development of the medicine I
Antimicrobial and anticancer drugs in clinical and preclinical trials (Yamada)

3

Materials for development of the medicine II
Antiplasmodial marine natural products (Yamada)4

Marine natural products for the tool of pharmacological studies (Yamada)

20

開講期間／Class period

2016年度／Academic Year 後期／Second Semester
2016/09/28 ~ 2017/03/31

必修選択／Required/Elective class

選択／elective

単位数(一般/編入/留学)／Credits
0.5(general/admission/overseas)

時間割コード／Time schedule code

20165503181005

科目番号／Subject code

科目ナンバリングコード／Numbering Code

BMMP52322785

授業科目名／Subject

Resources of Natural Medicines／Resources of Natural Medicines for Infectious Diseases

編集担当教員／Professor in charge ofputting together the course syllabus

真木

俊英／Maki Toshihide

授業担当教員名（科目責任者）／Professor in charge of the subject

真木

俊英／Maki Toshihide

授業担当教員名（オムニバス科目等）／Professor(s)真木

俊英／Maki Toshihide

科目分類／Class type

講義科目（区分Ｄ）, 特別コースの授業科目／NUPGP

対象年次／Year

1, 2

学期／Semester

教室／Class room
対象学生（クラス等）

曜日・校時／Day・Period

講義形態／Class Form

金／Fri 255031810

講義／Lecture〔薬学〕本館５階リフレッシュルーム／Pharmaceutical School 5th floor refresh room

/Object Student

Master course

担当教員Eメールアドレス/E‑mail address

maki@nagasaki‑u.ac.jp

担当教員研究室/Laboratory

Structure Analysis for Chemicals

担当教員TEL/Tel

095‑819‑2465

担当教員オフィスアワー/Office hours

Mon. ‑ Fri. 12:00 ‑ 13:00
You will learn basic of nuclear magnetic resonance spectrometer and mass spectrometer

授業の概要及び位置づけ/Course Outline andwhich are essential instruments for structure analysis for chemicals including infectious
Objectives
diseases.
授業到達目標/Goal
授業方法（学習指導法）/Method

授業内容/Class outline/Con

キーワード/Key word
教科書・教材・参考書/Textbook,Teachingmaterial,and Reference book
成績評価の方法・基準等/Evaluation

The ability to explain basic of NMR and Mass spectrometer.
The ability to select rational instruments for structure analysis of target molecules.
Educational training for structure analysis of chemicals, searching of chemicals, related
to infectious diseases.
Almost all medical supplies are low molecule organic compounds. In order to advance drug
design and search research, it becomes skilled about a means to get to know the structureof a molecule exactly, and the capability to consider a molecule function based on arational molecular structure model is searched for. You learn about the basic principleof a nuclear‑magnetic‑resonance (NMR) method and mass spectrometry and application which
are an indispensable measuring method, in order to conduct the structural analysis of alow molecule organic compound.
nuclear magnitic resonance, mass spectrometry, chemistry, structure
Reference books: High‑Resolution NMR Techniques in Organic Chemistry, Understanding mass
spectra, etc.
Report (60%) and discussion (40%) in the class受講要件（履修条件）/Requirements

アクセシビリティ/Accessibility

In order to ensure equal educational opportunities for all students, Nagasaki University
strives to remove societal barriers that may interfere with academic activities, and toprovide reasonable accommodations as necessary and appropriate. If you have any questions
or concerns regarding reasonable accommodations or other support in this class, pleasefeel free to talk to the instructor (contact information above), or contact the Student
Accessibility Office.
Student Accessibility Office contact information（TEL）095‑819‑2006（FAX）095‑819‑2948（E‑MAIL）support@ml.nagasaki‑u.ac.jp

備考（URL）/Remarks(URL)
学生へのメッセージ/Message for students

LACS may be used for distribution of documents and announcement about this class.

授業計画詳細／Course Schedule
回(日時)／Time(date and time)

授業内容／Contents

1st

Basic of nuclear magnetic resonance spectrometer with vector model.

2nd

Advanced techniques of nuclear magnetic resonance spectrometer with vector model.

3rd

Basic of mass spectrometer: ionization methods and fragmentation pattern.

4th

Discussion about practical problems in structural analysis of chemicals.

21

2016年度／Academic Year
2年通年／Two years whole year

曜日・校時／Day・Period

開講期間／Class period

2016/09/27～2018/9/30

必修選択／Required/Elective class

必修／required

単位数(一般/編入/留学)／Credits
4.0(general/admission/overseas)

時間割コード／Time schedule code

201655082000A0

科目番号／Subject code

科目ナンバリングコード／Numbering Code

BMMP66812796

授業科目名／Subject

Exercise Biomedical Sciences：Cell Regulation／Exercise Biomedical Sciences

編集担当教員／Professor in charge ofputting together the course syllabus

武田弘資／Takeda Kohsuke, 谷村

授業担当教員名（科目責任者）／Professor in charge of the subject

武田弘資／Takeda Kohsuke

授業担当教員名（オムニバス科目等）／Professor(s)武田弘資／Takeda Kohsuke, 谷村

科目分類／Class type

Exercise Biomedical Sciences

対象年次／Year

1年,2年

学期／Semester

教室／Class room
対象学生（クラス等）

他/Others

55082000

進／Tanimura Susumu

進／Tanimura Susumu

講義形態／Class Form

演習／Seminar〔薬学〕各担当教員研究室／Laboratory/Object Student

Master course

担当教員Eメールアドレス/E‑mail address

takeda‑k@nagasaki‑u.ac.jp

担当教員研究室/Laboratory

Cell Regulation

担当教員TEL/Tel

095‑819‑2417

At any time by e‑mail担当教員オフィスアワー/Office hours
授業の概要及び位置づけ/Course Outline and To learn the approaches to elucidate the mechanisms of intracellular signal transduction
regulating various cellular functions.
Objectives

授業到達目標/Goal

To understand research articles in English and to acquire how to present and discuss
scientific data.

授業方法（学習指導法）/Method

Seminar

授業内容/Class outline/Con

Present and discuss selected research articles on the following subject.
1. Novel mechanisms and significance of intracellular signaling.
2. Signal transduction regulating cellular stress response.
3. Cell signaling and various diseases.
4. Mitochondrial functions in cell signaling.

キーワード/Key word
教科書・教材・参考書/Textbook,Teachingmaterial,and Reference book
成績評価の方法・基準等/Evaluation

signal transduction, cell signaling, stress response, cancer, metabolism, mitochondria

受講要件（履修条件）/Requirements

None

アクセシビリティ/Accessibility

Scientific journals
Presentation and discussion skills.
In order to ensure equal educational opportunities for all students, Nagasaki University
strives to remove societal barriers that may interfere with academic activities, and toprovide reasonable accommodations as necessary and appropriate. If you have any questions
or concerns regarding reasonable accommodations or other support in this class, pleasefeel free to talk to the instructor (contact information above), or contact the Student
Accessibility Office.
Student Accessibility Office contact information（TEL）095‑819‑2006（FAX）095‑819‑2948（E‑MAIL）support@ml.nagasaki‑u.ac.jp

備考（URL）/Remarks(URL)
学生へのメッセージ/Message for students

222016年度／Academic Year
2年通年／Two years whole year

曜日・校時／Day・Period

開講期間／Class period

2016/09/27～2018/9/30

必修選択／Required/Elective class

必修／required

単位数(一般/編入/留学)／Credits
16.0(general/admission/overseas)

時間割コード／Time schedule code

201655082010C0

科目番号／Subject code

科目ナンバリングコード／Numbering Code

BMMP66912796

授業科目名／Subject

Experiment Biomedical Sciences：Cell Regulation／Experiment Biomedical Sciences

編集担当教員／Professor in charge ofputting together the course syllabus

武田

学期／Semester

授業担当教員名（科目責任者）／Professor in charge of the subject

弘資／Takeda Kohsuke, 谷村

武田

科目分類／Class type

Experiment Biomedical Sciences

対象年次／Year

1年,2年

対象学生（クラス等）

55082010

進／Tanimura Susumu

弘資／Takeda Kohsuke

武武田

授業担当教員名（オムニバス科目等）／Professor(s)教室／Class room

他/Others

弘資／Takeda Kohsuke, 谷村進／Tanimura Susumu

講義形態／Class Form

実験／Experiment〔薬学〕各担当教員研究室／Laboratory/Object Student

Master course

担当教員Eメールアドレス/E‑mail address

takeda‑k@nagasaki‑u.ac.jp

担当教員研究室/Laboratory

Cell Regulation

担当教員TEL/Tel

095‑819‑2417

At any time by e‑mail担当教員オフィスアワー/Office hours
授業の概要及び位置づけ/Course Outline and To learn the approaches to elucidate the mechanisms of intracellular signal transduction
regulating various cellular functions.
Objectives

授業到達目標/Goal

To plan and perform appropriate experiments independently to obtain data for publicationin scientific journals.

授業方法（学習指導法）/Method

Experiments

授業内容/Class outline/Con

Plan and perform experiments for each research project and discuss the resulting datawith instructors and laboratory members.

キーワード/Key word
教科書・教材・参考書/Textbook,Teachingmaterial,and Reference book
成績評価の方法・基準等/Evaluation

signal transduction, cell signaling, stress response, cancer, metabolism, mitochondria

受講要件（履修条件）/Requirements

None

アクセシビリティ/Accessibility

Technical and scientific achievements.
In order to ensure equal educational opportunities for all students, Nagasaki University
strives to remove societal barriers that may interfere with academic activities, and toprovide reasonable accommodations as necessary and appropriate. If you have any questions
or concerns regarding reasonable accommodations or other support in this class, pleasefeel free to talk to the instructor (contact information above), or contact the Student
Accessibility Office.
Student Accessibility Office contact information（TEL）095‑819‑2006（FAX）095‑819‑2948（E‑MAIL）support@ml.nagasaki‑u.ac.jp

備考（URL）/Remarks(URL)
学生へのメッセージ/Message for students

23

2016年度／Academic Year
2年通年／Two years whole year

曜日・校時／Day・Period

開講期間／Class period

2016/09/27～2018/9/30

必修選択／Required/Elective class

必修／required

単位数(一般/編入/留学)／Credits
4.0(general/admission/overseas)

時間割コード／Time schedule code

201655082000A1

科目番号／Subject code

科目ナンバリングコード／Numbering Code

BMMP66812796

授業科目名／Subject

Exercise Biomedical Sciences：Pharmacology and Therapeutic Innovation／Exercise
Biomedical Sciences

編集担当教員／Professor in charge ofputting together the course syllabus

植田

弘師／Ueda Hiroshi, 塚原

授業担当教員名（科目責任者）／Professor in charge of the subject

植田弘師／Ueda Hiroshi

授業担当教員名（オムニバス科目等）／Professor(s)植田

弘師／Ueda Hiroshi, 塚原

科目分類／Class type

Exercise Biomedical Sciences

対象年次／Year

1, 2

学期／Semester

教室／Class room
対象学生（クラス等）

他／Others 055082000

完／Tsukahara Tamotsu

完／Tsukahara Tamotsu

講義形態／Class Form

演習／Seminar〔薬学〕各担当教員研究室／Laboratory/Object Student

Master course

担当教員Eメールアドレス/E‑mail address

ueda@nagasaki‑u.ac.jp
ttamotsu@nagasaki‑u.ac.jp

担当教員研究室/Laboratory

Pharmacology and Therapeutic Innovation

担当教員TEL/Tel

095‑819‑2421
095‑819‑2473

担当教員オフィスアワー/Office hours

Wed.12:00‑12:50 (Accept any question by e‑mail)Students comprehend original and review articles in molecular pharmacology area, andpresent the contents such as introduction, methods, results and discussion using
授業の概要及び位置づけ/Course Outline andPowerPoint slides. They discuss about the significance or controversial points in the
Objectives
report as well as authors
views. Audience including undergraduate, postgraduate andprofessors make comments and ask questions about the points, which are not clear.
Students can gain the skills to choose good reports of interest from databases.
Students can appropriately explain the report written in English.
授業到達目標/Goal
Students can discuss the significance of the report and related works.

授業方法（学習指導法）/Method

Seminar style
Class outline/
Through the introduction and discussion about the good reports, students learn thetechnology of presentation and knowledge of the advanced research.

授業内容/Class outline/Con

Contents/
By listening to the seminar given by elder students and professors, students learn thetechnology about the presentation and discussion skills. Regarding presentation, thechoice of topics for good reports and power‑point slide production. Regarding discussion,
they learn the logic and ability to talk.
The preparation of seminar starts with the choosing the report from the database using
PubMed and online journals. Students decide the report for presentation through a
discussion with senior students and professors. After intensive reading the report andrelated references, they produce the original figures and tables to make audience easily
understand the contents. Using the figures and tables in the report and original ones,
students explain the content of the report and discuss the importance of the paper taking
the comments by audience.

キーワード/Key word
教科書・教材・参考書/Textbook,Teachingmaterial,and Reference book
成績評価の方法・基準等/Evaluation

Research Journals (Nature, Nature Medicine, Nature Neuroscience, Science, Cell, PNAS,
J.Neuroscience)
Logical explanation and discussion (100%)

受講要件（履修条件）/Requirements24アクセシビリティ/Accessibility

In order to ensure equal educational opportunities for all students, Nagasaki University
strives to remove societal barriers that may interfere with academic activities, and toprovide reasonable accommodations as necessary and appropriate. If you have any questions
or concerns regarding reasonable accommodations or other support in this class, pleasefeel free to talk to the instructor (contact information above), or contact the Student
Accessibility Office.
Student Accessibility Office contact information（TEL）095‑819‑2006（FAX）095‑819‑2948（E‑MAIL）support@ml.nagasaki‑u.ac.jp

備考（URL）/Remarks(URL)
学生へのメッセージ/Message for students25

学期／Semester

2016年度／Academic Year
2年通年／Two years whole year

開講期間／Class period

22016/09/27～2018/9/30

必修選択／Required/Elective class

必修／required

単位数(一般/編入/留学)／Credits
16.0(general/admission/overseas)

時間割コード／Time schedule code

201655082010C1

科目番号／Subject code

科目ナンバリングコード／Numbering Code

BMMP66912796

授業科目名／Subject

Experiment Biomedical Sciences：Pharmacology and Therapeutic Innovation／Experiment
Biomedical Sciences

編集担当教員／Professor in charge ofputting together the course syllabus

植田

弘師／Ueda Hiroshi, 塚原

授業担当教員名（科目責任者）／Professor in charge of the subject

植田弘師／Ueda Hiroshi

授業担当教員名（オムニバス科目等）／Professor(s)植田

弘師／Ueda Hiroshi, 塚原

科目分類／Class type

Experiment Biomedical Sciences

対象年次／Year

1, 2

教室／Class room
対象学生（クラス等）

曜日・校時／Day・Period

他／Others 055082010

完／Tsukahara Tamotsu

完／Tsukahara Tamotsu

講義形態／Class Form

実験／Experiment〔薬学〕各担当教員研究室／Laboratory/Object Student

Master course

担当教員Eメールアドレス/E‑mail address

ueda@nagasaki‑u.ac.jp
ttamotsu@nagasaki‑u.ac.jp

担当教員研究室/Laboratory

Pharmacology and Therapeutic Innovation

担当教員TEL/Tel

095‑819‑2421
095‑819‑2473

担当教員オフィスアワー/Office hours

Wed.12:00‑12:50 (Accept any question by e‑mail)Students comprehend original and review articles in molecular pharmacology area, andpresent the contents such as introduction, methods, results and discussion using
授業の概要及び位置づけ/Course Outline andPowerPoint slides. They discuss about the significance or controversial points in the
Objectives
report as well as authors
views. Audience including undergraduate, postgraduate andprofessors make comments and ask questions about the points, which are not clear.
Students can gain the skills to choose good reports of interest from databases.
Students can appropriately explain the report written in English.
授業到達目標/Goal
Students can discuss the significance of the report and related works.

授業方法（学習指導法）/Method

Seminar style
Class outline/
Through the introduction and discussion about the good reports, students learn thetechnology of presentation and knowledge of the advanced research.

授業内容/Class outline/Con

Contents/
By listening to the seminar given by elder students and professors, students learn thetechnology about the presentation and discussion skills. Regarding presentation, thechoice of topics for good reports and power‑point slide production. Regarding discussion,
they learn the logic and ability to talk.
The preparation of seminar starts with the choosing the report from the database using
PubMed and online journals. Students decide the report for presentation through a
discussion with senior students and professors. After intensive reading the report andrelated references, they produce the original figures and tables to make audience easily
understand the contents. Using the figures and tables in the report and original ones,
students explain the content of the report and discuss the importance of the paper taking
the comments by audience.

キーワード/Key word
教科書・教材・参考書/Textbook,Teachingmaterial,and Reference book
成績評価の方法・基準等/Evaluation

Research Journals (Nature, Nature Medicine, Nature Neuroscience, Science, Cell, PNAS,
J.Neuroscience)
Logical explanation and discussion (100%)

受講要件（履修条件）/Requirements

26アクセシビリティ/Accessibility

In order to ensure equal educational opportunities for all students, Nagasaki University
strives to remove societal barriers that may interfere with academic activities, and toprovide reasonable accommodations as necessary and appropriate. If you have any questions
or concerns regarding reasonable accommodations or other support in this class, pleasefeel free to talk to the instructor (contact information above), or contact the Student
Accessibility Office.
Student Accessibility Office contact information（TEL）095‑819‑2006（FAX）095‑819‑2948（E‑MAIL）support@ml.nagasaki‑u.ac.jp

備考（URL）/Remarks(URL)
学生へのメッセージ/Message for students27

2016年度／Academic Year
2年通年／Two years whole year

曜日・校時／Day・Period

開講期間／Class period

2016/09/27～2018/9/30

必修選択／Required/Elective class

必修／required

単位数(一般/編入/留学)／Credits
4.0(general/admission/overseas)

時間割コード／Time schedule code

201655082000A2

科目番号／Subject code

科目ナンバリングコード／Numbering Code

BMMP66812796

授業科目名／Subject

Exercise Biomedical Sciences：Pharmaceutical Chemistry／Exercise Biomedical Sciences

編集担当教員／Professor in charge ofputting together the course syllabus

田中

正一／Tanaka Masakazu, 大庭

授業担当教員名（科目責任者）／Professor in charge of the subject

田中

正一／Tanaka Masakazu

授業担当教員名（オムニバス科目等）／Professor(s)田中

正一／Tanaka Masakazu, 大庭

科目分類／Class type

Exercise Biomedical Sciences

対象年次／Year

1, 2

学期／Semester

教室／Class room
対象学生（クラス等）

他／Others 055082000

誠／Oba Makoto, 上田

篤志／Ueda Atsushi

誠／Oba Makoto, 上田

篤志／Ueda Atsushi

講義形態／Class Form

演習／Seminar〔薬学〕各担当教員研究室／Laboratory/Object Student

Master course

担当教員Eメールアドレス/E‑mail addressmatanaka@nagasaki‑u.ac.jp

担当教員研究室/Laboratory

Pharmaceutical Chemistry

担当教員TEL/Tel

095‑819‑2423

Tuesday 16:00‑18:00
担当教員オフィスアワー/Office hours
授業の概要及び位置づけ/Course Outline and To profound the specialized knowledge and follow the frontier of relevant research field
through literature reading and presentation at the group meeting.
Objectives

授業到達目標/Goal

To master the skill of literature searching, and to develop the ability to exactly
understanding the key points of the charged literature articles and presentation skill.

授業方法（学習指導法）/Method

seminar
The student should select one or more original research papers each time that seem to beinteresting to most of the group members from the main international journals, read
carefully, try the best to understand the contexts, and present the reported research
work before the group members.

授業内容/Class outline/Con
1st & 2nd Introduction on literature searching
3rd ‑30th Present original research literature papers relating to the research topic of
him/herself and discuss

キーワード/Key word
教科書・教材・参考書/Textbook,Teachingmaterial,and Reference book
成績評価の方法・基準等/Evaluation

literature, presentation
Scientific journals in English
Reading ability and presentation skill (100%)

受講要件（履修条件）/Requirements

アクセシビリティ/Accessibility

In order to ensure equal educational opportunities for all students, Nagasaki University
strives to remove societal barriers that may interfere with academic activities, and toprovide reasonable accommodations as necessary and appropriate. If you have any questions
or concerns regarding reasonable accommodations or other support in this class, pleasefeel free to talk to the instructor (contact information above), or contact the Student
Accessibility Office.
Student Accessibility Office contact information（TEL）095‑819‑2006（FAX）095‑819‑2948（E‑MAIL）support@ml.nagasaki‑u.ac.jp

備考（URL）/Remarks(URL)
学生へのメッセージ/Message for students

Not only understanding the content of journal, but also presentation skill are important.

28

2016年度／Academic Year
2年通年／Two years whole year

曜日・校時／Day・Period

開講期間／Class period

2016/09/27～2018/9/30

必修選択／Required/Elective class

必修／required

単位数(一般/編入/留学)／Credits
16.0(general/admission/overseas)

時間割コード／Time schedule code

201655082010C2

科目番号／Subject code

科目ナンバリングコード／Numbering Code

BMMP66912796

学期／Semester

55082010

Experiment Biomedical Sciences：Pharmaceutical Chemistry／Experiment Biomedical Sciences

授業科目名／Subject
編集担当教員／Professor in charge ofputting together the course syllabus

田中

正一／Tanaka Masakazu, 大庭

授業担当教員名（科目責任者）／Professor in charge of the subject

田中

正一／Tanaka Masakazu

授業担当教員名（オムニバス科目等）／Professor(s)田中

正一／Tanaka Masakazu, 大庭

科目分類／Class type

Experiment Biomedical Sciences

対象年次／Year

1, 2

教室／Class room
対象学生（クラス等）

他／Others 0

誠／Oba Makoto

誠／Oba Makoto

講義形態／Class Form

実験／Experiment〔薬学〕各担当教員研究室／Laboratory/Object Student

Master course

担当教員Eメールアドレス/E‑mail addressmatanaka@nagasaki‑u.ac.jp

担当教員研究室/Laboratory

Pharmaceutical Chemistry

担当教員TEL/Tel

095‑819‑2423

Tuesday 16:00‑18:00
担当教員オフィスアワー/Office hours
授業の概要及び位置づけ/Course Outline andTo learn the fundamental experimental manipulations and techniques.
Objectives

授業到達目標/Goal

Can carry out the routine experiments independently, and can summarize and present theexperimental results.

授業方法（学習指導法）/Method

Seminar.

授業内容/Class outline/Con

A research subject will be assigned to each student, which is followed by an experimental
training. During this period, the students are required to master the fundamental
techniques for doing synthetic organic experiments. After that the students should workon their own research plan. Research results should be summarized and presented at thegroup meeting periodically.

キーワード/Key word
教科書・教材・参考書/Textbook,Teachingmaterial,and Reference book
成績評価の方法・基準等/Evaluation

Scientific journals

受講要件（履修条件）/Requirements

アクセシビリティ/Accessibility

In order to ensure equal educational opportunities for all students, Nagasaki University
strives to remove societal barriers that may interfere with academic activities, and toprovide reasonable accommodations as necessary and appropriate. If you have any questions
or concerns regarding reasonable accommodations or other support in this class, pleasefeel free to talk to the instructor (contact information above), or contact the Student
Accessibility Office.
Student Accessibility Office contact information（TEL）095‑819‑2006（FAX）095‑819‑2948（E‑MAIL）support@ml.nagasaki‑u.ac.jp

備考（URL）/Remarks(URL)
学生へのメッセージ/Message for students

Discussions on experimental results are important.

29

2016年度／Academic Year
2年通年／Two years whole year

曜日・校時／Day・Period

開講期間／Class period

2016/09/27～2018/9/30

必修選択／Required/Elective class

必修／required

単位数(一般/編入/留学)／Credits
4.0(general/admission/overseas)

時間割コード／Time schedule code

201655082000A3

科目番号／Subject code

科目ナンバリングコード／Numbering Code

BMMP66812796

授業科目名／Subject

Exercise Biomedical Sciences：Pharmaceutical Organic Chemistry／Exercise Biomedical
Sciences

編集担当教員／Professor in charge ofputting together the course syllabus

石原淳／Ishihara Jun

授業担当教員名（科目責任者）／Professor in charge of the subject

石原淳／Ishihara Jun

授業担当教員名（オムニバス科目等）／Professor(s)石原

淳／Ishihara Jun

科目分類／Class type

Exercise Biomedical Sciences

対象年次／Year

1, 2

学期／Semester

教室／Class room
対象学生（クラス等）

講義形態／Class Form

他／Others 0, 日／Sun 0

55082000

演習／Seminar〔薬学〕各担当教員研究室／Laboratory/Object Student

Master course

担当教員Eメールアドレス/E‑mail address

jishi@nagasaki‑u.ac.jp

担当教員研究室/Laboratory

Pharmaceutical Organic Chemistry

担当教員TEL/Tel

819‑2427

Mon‑Fri 13:00‑18:00
担当教員オフィスアワー/Office hours
授業の概要及び位置づけ/Course Outline and To attain the ability to properly access the databases and read journals and books to get
the information required for the synthetic studies.
Objectives

授業到達目標/Goal
授業方法（学習指導法）/Method
授業内容/Class outline/Con
キーワード/Key word
教科書・教材・参考書/Textbook,Teachingmaterial,and Reference book
成績評価の方法・基準等/Evaluation(1) Be able to get the proper journals and books from databases.
(2) Be able to understand the contents of the journals and books.
(3) Be able to discuss the chemistry described in the journals and books.
The students select the subjects on synthetic chemistry from the up‑to‑date journals andbooks and present succinctly the topics in the class.
Class outline/
The students select the subjects on synthetic chemistry from the up‑to‑date journals andbooks and discuss the topics in the class.

Journals (JACS, JOC, OL, TL, Angew.Chem.Int.Ed., Chem.Commun, etc)
Understanding (100%)

受講要件（履修条件）/Requirements

アクセシビリティ/Accessibility

In order to ensure equal educational opportunities for all students, Nagasaki University
strives to remove societal barriers that may interfere with academic activities, and toprovide reasonable accommodations as necessary and appropriate. If you have any questions
or concerns regarding reasonable accommodations or other support in this class, pleasefeel free to talk to the instructor (contact information above), or contact the Student
Accessibility Office.
Student Accessibility Office contact information（TEL）095‑819‑2006（FAX）095‑819‑2948（E‑MAIL）support@ml.nagasaki‑u.ac.jp

備考（URL）/Remarks(URL)
学生へのメッセージ/Message for students
授業計画詳細／Course Schedule
回(日時)／Time(date and time)
1st
2nd
3rd

授業内容／Contents
Learn how to get proper journals and books using databases.
Learn how to utilize the information obtained for carrying out the synthetic studies.
Present the subjects on synthetic chemistry from the up‑to‑date journals and books anddiscuss the topics in the class.
Contents above (1st‑3rd) are repeated.

30

2016年度／Academic Year
2年通年／Two years whole year

曜日・校時／Day・Period

開講期間／Class period

2016/09/27～2018/9/30

必修選択／Required/Elective class

必修／required

単位数(一般/編入/留学)／Credits
16.0(general/admission/overseas)

時間割コード／Time schedule code

201655082010C3

科目番号／Subject code

科目ナンバリングコード／Numbering Code

BMMP66912796

授業科目名／Subject

Experiment Biomedical Sciences：Pharmaceutical Organic Chemistry／Experiment Biomedical
Sciences

編集担当教員／Professor in charge ofputting together the course syllabus

石原淳／Ishihara Jun

授業担当教員名（科目責任者）／Professor in charge of the subject

石原淳／Ishihara Jun

授業担当教員名（オムニバス科目等）／Professor(s)石原

淳／Ishihara Jun

科目分類／Class type

Experiment Biomedical Sciences

対象年次／Year

1, 2

学期／Semester

教室／Class room
対象学生（クラス等）

講義形態／Class Form

他／Others 0, 日／Sun 0

55082010

実験／Experiment〔薬学〕各担当教員研究室／Laboratory/Object Student

Master course

担当教員Eメールアドレス/E‑mail address

jishi@nagasaki‑u.ac.jp

担当教員研究室/Laboratory

Pharmaceutical Organic Chemistry

担当教員TEL/Tel

819‑2427

Mon‑Fri 13:00‑18:00
担当教員オフィスアワー/Office hours
授業の概要及び位置づけ/Course Outline andTo attain the ability to construct the target molecules.
Objectives

授業到達目標/Goal
授業方法（学習指導法）/Method
授業内容/Class outline/Con
キーワード/Key word
教科書・教材・参考書/Textbook,Teachingmaterial,and Reference book
成績評価の方法・基準等/Evaluation(1) Be able to make a reasonable synthetic plan for the construction of the target
molecule.
(2) Be able to carry out the reactions to construct the target molecule.
The students carry out the experiments in the synthesis of the structurally andbiologically intriguing natural products.
Class outline/
The synthesis of biologically active natural products.
organic chemistry, organic synthesis, natural product
Journals (JACS, JOC, OL, TL, Angew.Chem.Int.Ed., Chem.Commun, etc)
Thesis (100%)

受講要件（履修条件）/Requirements

アクセシビリティ/Accessibility

In order to ensure equal educational opportunities for all students, Nagasaki University
strives to remove societal barriers that may interfere with academic activities, and toprovide reasonable accommodations as necessary and appropriate. If you have any questions
or concerns regarding reasonable accommodations or other support in this class, pleasefeel free to talk to the instructor (contact information above), or contact the Student
Accessibility Office.
Student Accessibility Office contact information（TEL）095‑819‑2006（FAX）095‑819‑2948（E‑MAIL）support@ml.nagasaki‑u.ac.jp

備考（URL）/Remarks(URL)
学生へのメッセージ/Message for students
授業計画詳細／Course Schedule
回(日時)／Time(date and time)

授業内容／Contents

1stCollect the information concerning the target molecule by searching the databases andreading journals, and then make synthetic plans.

2nd
3rd
4th
5th

Determine one synthetic route by the evaluation of the above‑mentioned synthetic plans.
Construct the required key intermediates.
Present the progress report in the group seminar and discuss the results.
Combine the intermediates prepared together to get the advanced intermediates.

31

6th
7th
8th
9th

Achieve the synthesis of the target molecule and confirm the structure by spectroscopic
analyses.
Present the final report in the group seminar and discuss the results.
Prepare a manuscript of the synthetic work for publication.
Prepare a thesis on the synthetic work.

32

2016年度／Academic Year
2年通年／Two years whole year

曜日・校時／Day・Period

開講期間／Class period

2016/09/27～2018/9/30

必修選択／Required/Elective class

必修／required

単位数(一般/編入/留学)／Credits
4.0(general/admission/overseas)

時間割コード／Time schedule code

201655082000A4

科目番号／Subject code

科目ナンバリングコード／Numbering Code

BMMP66812796

授業科目名／Subject

Exercise Biomedical Sciences：Chemistry for Pharmaceuticals／Exercise Biomedical Sciences

編集担当教員／Professor in charge ofputting together the course syllabus

尾野村治／Onomura Osamu, 栗山

授業担当教員名（科目責任者）／Professor in charge of the subject

尾野村治／Onomura Osamu

授業担当教員名（オムニバス科目等）／Professor(s)尾野村治／Onomura Osamu, 栗山

科目分類／Class type

Exercise Biomedical Sciences

対象年次／Year

1, 2

学期／Semester

教室／Class room
対象学生（クラス等）

他／Others 055082000

正巳／Kuriyama Masami

正巳／Kuriyama Masami

講義形態／Class Form

演習／Seminar〔薬学〕各担当教員研究室／Laboratory/Object Student

Master course

担当教員Eメールアドレス/E‑mail address

onomura@nagasaki‑u.ac.jp

担当教員研究室/Laboratory

Synthetic Chemistry for Pharmaceuticals

担当教員TEL/Tel

095‑819‑2429

担当教員オフィスアワー/Office hours

Mon. ‑ Fri. 10:30 ‑ 18:00
A major object is to stimulate you by learning what subjects are now current important

授業の概要及び位置づけ/Course Outline and topics in the field of synthetic organic chemistry directed toward medicinal chemistry
through identifying some important literatures in a variety of related academic articles
Objectives
授業到達目標/Goal
授業方法（学習指導法）/Method
授業内容/Class outline/Con

followed by brief description of the contents and discussions.
You can extract useful research articles by data bases and get necessary original papers.
Furthermore, you can understand the contents of the literatures.
Educational training for presentation and discussion concerning about your research arecarried out.
You read original articles written in English. By selection of research articles related
to your research and brief summary of the contents, you get new information andpresentation skills.

キーワード/Key word
教科書・教材・参考書/Textbook,Teachingmaterial,and Reference book
成績評価の方法・基準等/Evaluation

Search for academic literatures, Summarization of literatures, Presentation

受講要件（履修条件）/Requirements

None

アクセシビリティ/Accessibility

Academic journals （JACS, JOC, OL, Tetrahedron Letters, Angew. Chem. Int. Ed., Chem.
Commun. Etc.）
Understanding of research articles (100%)
In order to ensure equal educational opportunities for all students, Nagasaki University
strives to remove societal barriers that may interfere with academic activities, and toprovide reasonable accommodations as necessary and appropriate. If you have any questions
or concerns regarding reasonable accommodations or other support in this class, pleasefeel free to talk to the instructor (contact information above), or contact the Student
Accessibility Office.
Student Accessibility Office contact information（TEL）095‑819‑2006（FAX）095‑819‑2948（E‑MAIL）support@ml.nagasaki‑u.ac.jp

備考（URL）/Remarks(URL)
学生へのメッセージ/Message for students

In advance, read carefully more than three original papers.

授業計画詳細／Course Schedule
回(日時)／Time(date and time)

授業内容／Contents

1

Lecture on search skills of data bases (Scifinder, Beilstein).(Onomura & Kuriyama)

2

Lecture about methods to get original articles.(O & K)

3
4
5

Introducing one original literature related to your research, and discussion of thecontent (1) (O & K)
Introducing one original literature related to your research, and discussion of thecontent (2) (O & K)
Introducing one original literature related to your research, and discussion of thecontent (3) (O & K)

33

6
7
8
9
10
11
12
13
14
15

Introducing one original literature related to your research, and discussion of thecontent (4) (O & K)
Introducing one original literature related to your research, and discussion of thecontent (5) (O & K)
Introducing one original literature related to your research, and discussion of thecontent (6) (O & K)
Introducing one original literature related to your research, and discussion of thecontent (7) (O & K)
Introducing one original literature related to your research, and discussion of thecontent (8) (O & K)
Introducing one original literature related to your research, and discussion of thecontent (9) (O & K)
Introducing one original literature related to your research, and discussion of thecontent (10) (O & K)
Introducing one original literature related to your research, and discussion of thecontent (11) (O & K)
Introducing one original literature related to your research, and discussion of thecontent (12) (O & K)
Introducing one original literature related to your research, and discussion of thecontent (13) (O & K)

34

2016年度／Academic Year
2年通年／Two years whole year

曜日・校時／Day・Period

開講期間／Class period

2016/09/27～2018/9/30

必修選択／Required/Elective class

必修／required

単位数(一般/編入/留学)／Credits
16.0(general/admission/overseas)

時間割コード／Time schedule code

201655082010C4

科目番号／Subject code

科目ナンバリングコード／Numbering Code

BMMP66912796

授業科目名／Subject

Experiment Biomedical Sciences：Chemistry for Pharmaceuticals／Experiment Biomedical
Sciences

編集担当教員／Professor in charge ofputting together the course syllabus

尾野村治／Onomura Osamu, 栗山

授業担当教員名（科目責任者）／Professor in charge of the subject

尾野村治／Onomura Osamu

授業担当教員名（オムニバス科目等）／Professor(s)尾野村治／Onomura Osamu, 栗山

科目分類／Class type

Experiment Biomedical Sciences

対象年次／Year

1, 2

学期／Semester

教室／Class room
対象学生（クラス等）

他／Others 055082010

正巳／Kuriyama Masami

正巳／Kuriyama Masami

講義形態／Class Form

実験／Experiment〔薬学〕各担当教員研究室／Laboratory/Object Student

Master course

担当教員Eメールアドレス/E‑mail address

onomura@nagasaki‑u.ac.jp

担当教員研究室/Laboratory

Synthetic Chemistry for Pharmaceuticals

担当教員TEL/Tel

095‑819‑2429

Mon. ‑ Fri. 10:30 ‑ 18:00
担当教員オフィスアワー/Office hours
授業の概要及び位置づけ/Course Outline and You learn how to do experiment to get new and fruitful results in synthetic organic
chemistry directed toward medicinal chemistry.
Objectives

授業到達目標/Goal

授業方法（学習指導法）/Method
授業内容/Class outline/Con

Planning rational synthetic routes to target molecules.
The ability to carry out basic reactions necessary for preparation of complicatedmolecules.
The skills to isolate desired products from reaction mixtures.
The ability to prepare manuscripts to control.
Educational training for searching, planning, experimental, and presentation skills
related to your research subject.
You read original literatures written in English. By selection of research articles
related to your research project and presentation of the contents, you get new
information and presentation skills.

キーワード/Key word
教科書・教材・参考書/Textbook,Teachingmaterial,and Reference book
成績評価の方法・基準等/Evaluation

Synthetic methods, Analysis of reaction mechanism, Comparison of experimental results

受講要件（履修条件）/Requirements

None

アクセシビリティ/Accessibility

Academic journals （JACS, JOC, OL, Tetrahedron Letters, Angew. Chem. Int. Ed., Chem.
Commun. etc.）, Data bases (Scifinder, Beilstein)Completion of research articles (100%).
In order to ensure equal educational opportunities for all students, Nagasaki University
strives to remove societal barriers that may interfere with academic activities, and toprovide reasonable accommodations as necessary and appropriate. If you have any questions
or concerns regarding reasonable accommodations or other support in this class, pleasefeel free to talk to the instructor (contact information above), or contact the Student
Accessibility Office.
Student Accessibility Office contact information（TEL）095‑819‑2006（FAX）095‑819‑2948（E‑MAIL）support@ml.nagasaki‑u.ac.jp

備考（URL）/Remarks(URL)
学生へのメッセージ/Message for students

In advance, master basic knowledge of organic chemistry.

授業計画詳細／Course Schedule
回(日時)／Time(date and time)

授業内容／Contents

1

Search data bases to extract academic articles, and Read the articles to get information
for preparation of target molecules.

2

Design new synthetic routes and plan synthetic experiment. (O & K)

3

Search and read academic articles related to the new routes. (O & K)

4Analysis of obtained information and determination of reasonable 3 synthetic routes. (O &
K)

35

5

Experiment of the 1st synthetic route. (O & K)

6

Experiment of the 2nd synthetic route. (O & K)

7

Experiment of the 3rd synthetic route. (O & K)

8

Comparison of experimental results by methods 1‑3 (O & K)

9

Presentation of research results to select the best method. (O & K)

10

Generality of selected synthetic method. (O & K)

11

Measurement of physical data. (O & K)

12

Experiments for analysis of reaction mechanism. (O & K)

13

Summarization of research results for presentation in a symposium. (O & K)

14

Presentation of research results in a symposium. (O & K)

15

Preparation of a manuscript to contributable to a journal. (O & K)

36

2016年度／Academic Year
2年通年／Two years whole year

曜日・校時／Day・Period

開講期間／Class period

2016/09/27～2018/9/30

必修選択／Required/Elective class

必修／required

単位数(一般/編入/留学)／Credits
16.0(general/admission/overseas)

時間割コード／Time schedule code

201655082010C5

科目番号／Subject code

科目ナンバリングコード／Numbering Code

BMMP66912796

授業科目名／Subject

Experiment Biomedical Sciences：Genome‑based Drug Discovery／Experiment Biomedical
Sciences

編集担当教員／Professor in charge ofputting together the course syllabus

岩田修永／Iwata Nobuhisa, 城谷

授業担当教員名（科目責任者）／Professor in charge of the subject

岩田

修永／Iwata Nobuhisa

授業担当教員名（オムニバス科目等）／Professor(s)岩田

修永／Iwata Nobuhisa, 城谷

科目分類／Class type

Experiment Biomedical Sciences

対象年次／Year

1, 2

学期／Semester

教室／Class room
対象学生（クラス等）

他／Others 055082010

圭朗／Shirotani Keiro

圭朗／Shirotani Keiro

講義形態／Class Form

実験／Experiment〔薬学〕各担当教員研究室／Laboratory/Object Student

Master course

担当教員Eメールアドレス/E‑mail address

iwata‑n@nagasaki‑u.ac.jp, keiroshiro@nagasaki‑u.ac.jp, asai@nagasaki‑u.ac.jp

担当教員研究室/Laboratory

Gene‑based Drug Discovery

担当教員TEL/Tel

095‑819‑2435 (Iwata), 095‑819‑2436 (Shirotani), 095‑819‑2437 (Asai)

Mon‑Fri. 13:00‑17:00
担当教員オフィスアワー/Office hours
授業の概要及び位置づけ/Course Outline and Designing an experimental plan to solve the problems, training experimental techniques,
and evaluating obtained results.
Objectives

授業到達目標/Goal

At the end of this class, the students should be able to:
Fulfill the experiments using appropriate methods and trained techniques according to theexperimental plan, and make a paper to publish in scientific journals.

授業方法（学習指導法）/Method

Practice a research according to instructors

direction.

Molecular biology of neurodegenerative diseases.

授業内容/Class outline/Con

キーワード/Key word

1st: molecular biological experiments
2nd: cell biological experiments
3rd: biochemical & enzymological experiments
4th: histochemical experiments
5th: animal experiments
Alzheimer's disease, pathogenesis, enzyme, recombinant DNA technology, animal model, drug
discovery, development of early diagnostic metho

教科書・教材・参考書/Textbook,Teachingmaterial,and Reference book
成績評価の方法・基準等/Evaluation

Journals (JBC, J Neurosci, Neuron, Nature & its sister journals, Science, Cell & its
sister journals, etc.)

受講要件（履修条件）/Requirements

None

アクセシビリティ/Accessibility

In order to ensure equal educational opportunities for all students, Nagasaki University
strives to remove societal barriers that may interfere with academic activities, and toprovide reasonable accommodations as necessary and appropriate. If you have any questions
or concerns regarding reasonable accommodations or other support in this class, pleasefeel free to talk to the instructor (contact information above), or contact the Student
Accessibility Office.
Student Accessibility Office contact information（TEL）095‑819‑2006（FAX）095‑819‑2948（E‑MAIL）support@ml.nagasaki‑u.ac.jp

Active participation 80%, and achievement 20%

備考（URL）/Remarks(URL)
学生へのメッセージ/Message for students

Professional training37

2016年度／Academic Year
2年通年／Two years whole year

曜日・校時／Day・Period

開講期間／Class period

2016/09/27～2018/9/30

必修選択／Required/Elective class

必修／required

単位数(一般/編入/留学)／Credits
4.0(general/admission/overseas)

時間割コード／Time schedule code

201655082000A5

科目番号／Subject code

科目ナンバリングコード／Numbering Code

BMMP66812796

学期／Semester

55082000

Exercise Biomedical Sciences：Genome‑based Drug Discovery／Exercise Biomedical Sciences

授業科目名／Subject
編集担当教員／Professor in charge ofputting together the course syllabus

岩田修永／Iwata Nobuhisa, 城谷

授業担当教員名（科目責任者）／Professor in charge of the subject

岩田

修永／Iwata Nobuhisa

授業担当教員名（オムニバス科目等）／Professor(s)岩田

修永／Iwata Nobuhisa, 城谷

科目分類／Class type

Exercise Biomedical Sciences

対象年次／Year

1, 2

教室／Class room
対象学生（クラス等）

他／Others 0

圭朗／Shirotani Keiro, 浅井将／Asai Masashi

圭朗／Shirotani Keiro, 浅井将／Asai Masashi

講義形態／Class Form

演習／Seminar〔薬学〕各担当教員研究室／Laboratory/Object Student

Master course

担当教員Eメールアドレス/E‑mail address

iwata‑n@nagasaki‑u.ac.jp, keiroshiro@nagasaki‑u.ac.jp, asai@nagasaki‑u.ac.jp

担当教員研究室/Laboratory

Gene‑based Drug Discovery

担当教員TEL/Tel

095‑819‑2435 (Iwata), 095‑819‑2436 (Shirotani), 095‑819‑2437 (Asai)

Mon‑Fri. 13:00‑17:00
担当教員オフィスアワー/Office hours
授業の概要及び位置づけ/Course Outline and Training search, selection and evaluation of information, and enhancing own problem‑
solving abilities
Objectives

授業到達目標/Goal

At the end of this class, the students should be able to:
Select appropriate information necessary for own research theme from overflowing
information.
Find out fundamental problem in own research field, and discuss it.
Find appropriate avenues to resolve

授業方法（学習指導法）/Method

Presentation using slides and discussion in a small group
Cultivate ability to find out fundamental problem in own research field and solve theproblem by oneself.

授業内容/Class outline/Con

キーワード/Key word

1st: Search appropriate information necessary for own research theme using PubMed and soon.
2nd: Select appropriate information from overflowing ones.
3rd: Peruse papers published in scientific journals
4th: Find out fundamental problem in own research field, and discuss it with
instructors.
Alzheimer's disease, pathogenesis, enzyme, recombinant DNA technology, animal model, drug
discovery, development of early diagnostic method

教科書・教材・参考書/Textbook,Teachingmaterial,and Reference book
成績評価の方法・基準等/Evaluation

Journals (J Biol Chem, J Neurosci, Neuron, Nature & its sister journals, Science, Cell &its sister journals, etc.)

受講要件（履修条件）/Requirements

None

アクセシビリティ/Accessibility

In order to ensure equal educational opportunities for all students, Nagasaki University
strives to remove societal barriers that may interfere with academic activities, and toprovide reasonable accommodations as necessary and appropriate. If you have any questions
or concerns regarding reasonable accommodations or other support in this class, pleasefeel free to talk to the instructor (contact information above), or contact the Student
Accessibility Office.
Student Accessibility Office contact information（TEL）095‑819‑2006（FAX）095‑819‑2948（E‑MAIL）support@ml.nagasaki‑u.ac.jp

Active participation 80%, and achievement 20%

備考（URL）/Remarks(URL)
学生へのメッセージ/Message for students

professional training38

2016年度／Academic Year
2年通年／Two years whole year

曜日・校時／Day・Period

開講期間／Class period

2016/09/27～2018/9/30

必修選択／Required/Elective class

必修／required

単位数(一般/編入/留学)／Credits
4.0(general/admission/overseas)

時間割コード／Time schedule code

201655082000A6

科目番号／Subject code

科目ナンバリングコード／Numbering Code

BMMP66812796

授業科目名／Subject

Exercise Biomedical Sciences：Molecular Pharmacology of infectious Agents／Exercise
Biomedical Sciences

学期／Semester

編集担当教員／Professor in charge ofputting together the course syllabus

小林信之／Kobayashi Nobuyuki, 北里

小林信之／Kobayashi Nobuyuki

授業担当教員名（オムニバス科目等）／Professor(s)小林信之／Kobayashi Nobuyuki, 北里

科目分類／Class type

Exercise Biomedical Sciences

対象年次／Year1, 2

授業担当教員名（科目責任者）／Professor in charge of the subject

教室／Class room
対象学生（クラス等）

他／Others 0, 日／Sun 0

55082000

海雄／Kitazato Kaio, 春山

貴弘／Haruyama Takahiro

海雄／Kitazato Kaio, 春山

貴弘／Haruyama Takahiro

講義形態／Class Form

演習／Seminar〔薬学〕各担当教員研究室／Laboratory/Object Student

Master course

担当教員Eメールアドレス/E‑mail address

nobnob@nagasaki‑u.ac.jp

担当教員研究室/Laboratory

Molecular Pharmacology of infectious Agents

担当教員TEL/Tel

095‑819‑2456

Any time but need apointment
担当教員オフィスアワー/Office hours
授業の概要及び位置づけ/Course Outline andTo learn the nature of infectious agents
Objectives
Be able to understand English articles and recognize nature of infectious agents.
授業到達目標/Goal

授業方法（学習指導法）/Method

Use selected articles published in medical journals.
Read medical articles published in English and understand the contents.

授業内容/Class outline/Con

キーワード/Key word
教科書・教材・参考書/Textbook,Teachingmaterial,and Reference book
成績評価の方法・基準等/Evaluation

Contents/
1st ‑ 10th : Basic Bacteriology.
11th ‑ 20th : Basic Virology.
21st ‑ 30th : Infectious Diseases.
Bacteria, Virus, Infectious Diseases

Report

受講要件（履修条件）/Requirements
アクセシビリティ/Accessibility
備考（URL）/Remarks(URL)
学生へのメッセージ/Message for students

39

2016年度／Academic Year
2年通年／Two years whole year

曜日・校時／Day・Period

開講期間／Class period

2016/09/27～2018/9/30

必修選択／Required/Elective class

必修／required

単位数(一般/編入/留学)／Credits
16.0(general/admission/overseas)

時間割コード／Time schedule code

201655082010C6

科目番号／Subject code

科目ナンバリングコード／Numbering Code

BMMP66912796

授業科目名／Subject

Experiment Biomedical Sciences：Molecular Pharmacology of infectious Agents／Experiment
Biomedical Sciences

学期／Semester

編集担当教員／Professor in charge ofputting together the course syllabus

小林信之／Kobayashi Nobuyuki, 北里

小林信之／Kobayashi Nobuyuki

授業担当教員名（オムニバス科目等）／Professor(s)小林信之／Kobayashi Nobuyuki, 北里

科目分類／Class type

Experiment Biomedical Sciences

対象年次／Year1, 2

授業担当教員名（科目責任者）／Professor in charge of the subject

教室／Class room
対象学生（クラス等）

他／Others 0, 日／Sun 0

55082010

海雄／Kitazato Kaio, 春山

貴弘／Haruyama Takahiro

海雄／Kitazato Kaio, 春山

貴弘／Haruyama Takahiro

講義形態／Class Form

実験／Experiment〔薬学〕各担当教員研究室／Laboratory/Object Student

Master course

担当教員Eメールアドレス/E‑mail address

nobnob@nagasaki‑u.ac.jp

担当教員研究室/Laboratory

Molecular Pharmacology of infectious Agents

担当教員TEL/Tel

095‑819‑2456

Any time but need apointment
担当教員オフィスアワー/Office hours
授業の概要及び位置づけ/Course Outline andTo learn the nature of infectious agents.
Objectives
Be able to understand English articles and recognize nature of infectious agents.
授業到達目標/Goal

授業方法（学習指導法）/Method

Use selected articles published in medical journals.
Read medical articles published in English and understand the contents.

授業内容/Class outline/Con

キーワード/Key word
教科書・教材・参考書/Textbook,Teachingmaterial,and Reference book
成績評価の方法・基準等/Evaluation

Contents/
1st ‑ 10th : Basic Bacteriology.
11th ‑ 20th : Basic Virology.
21st ‑ 30th : Infectious Diseases.
Bacteria, Virus, Infectious Diseases

Report

受講要件（履修条件）/Requirements
アクセシビリティ/Accessibility
備考（URL）/Remarks(URL)
学生へのメッセージ/Message for students
授業計画詳細／Course Schedule
回(日時)／Time(date and time)

授業内容／Contents

1stSocial problems of emerging infectious diseases

2ndCharacterization of infectious agents

3rd

Molecular therapy of Infectious agents

4th

Molecular mechanism of replication of infectious agents

5th

Strategy for drug development of anti‑infectious agents

6th

Strategy for vaccine development of infectious agents

7th

Application of virus as vectors on human gene therapy

40

2016年度／Academic Year
2年通年／Two years whole year

曜日・校時／Day・Period

開講期間／Class period

2016/09/27～2018/9/30

必修選択／Required/Elective class

必修／required

単位数(一般/編入/留学)／Credits
4.0(general/admission/overseas)

時間割コード／Time schedule code

201655082000A7

科目番号／Subject code

科目ナンバリングコード／Numbering Code

BMMP66812796

授業科目名／Subject

Exercise Biomedical Sciences：Natural Product Chemistry／Exercise Biomedical Sciences

編集担当教員／Professor in charge ofputting together the course syllabus

田中隆／Tanaka Takashi, 松尾

授業担当教員名（科目責任者）／Professor in charge of the subject

田中隆／Tanaka Takashi

授業担当教員名（オムニバス科目等）／Professor(s)田中隆／Tanaka Takashi, 松尾

科目分類／Class type

Exercise Biomedical Sciences

対象年次／Year

1, 2

学期／Semester

教室／Class room
対象学生（クラス等）

他／Others 055082000

洋介／Matsuo Yosuke, 齋藤義紀／Saito Yoshinori

洋介／Matsuo Yosuke, 齋藤義紀／Saito Yoshinori

講義形態／Class Form

演習／Seminar〔薬学〕各担当教員研究室／Laboratory/Object Student

Master course

担当教員Eメールアドレス/E‑mail addresst‑tanaka@nagasaki‑u.ac.jp

担当教員研究室/Laboratory

Natural Product Chemistry

担当教員TEL/Tel

819‑2432

担当教員オフィスアワー/Office hours
授業の概要及び位置づけ/Course Outline andObjectives
授業到達目標/Goal

Any time (Please make appointment by E‑mail ）授業方法（学習指導法）/Method

Instruction and teaching in the labolatory

授業内容/Class outline/Con

Methods of structure determination and application.

キーワード/Key word
教科書・教材・参考書/Textbook,Teachingmaterial,and Reference book
成績評価の方法・基準等/Evaluation

Chromatography, spectroscopy, Plant, Natural medicine

How to isolate the natural compounds from plants, and how to determine the structure ofnatural compounds.
Get the ability to isolate Naturap products and determine the structure.

Textbooks of Natural product chemistry and Spectroscopic methods
Attitute and completion og thesis

受講要件（履修条件）/Requirements

アクセシビリティ/Accessibility

備考（URL）/Remarks(URL)

In order to ensure equal educational opportunities for all students, Nagasaki University
strives to remove societal barriers that may interfere with academic activities, and toprovide reasonable accommodations as necessary and appropriate. If you have any questions
or concerns regarding reasonable accommodations or other support in this class, pleasefeel free to talk to the instructor (contact information above), or contact the Student
Accessibility Office.
Student Accessibility Office contact information（TEL）095‑819‑2006（FAX）095‑819‑2948（E‑MAIL）support@ml.nagasaki‑u.ac.jp
http://www.ph.nagasaki‑u.ac.jp/lab/natpro/index‑j.html

学生へのメッセージ/Message for students
授業計画詳細／Course Schedule
回(日時)／Time(date and time)

授業内容／Contents

1

Introduction of spectroscopy, IR, UV, MS, NMR

2

1H NMR spectroscopy (1)3

1H NMR spectroscopy (2)41H NMR spectroscopy (3)513C NMR spectroscopy (1)613C NMR spectroscopy (2)7IR, UV, and CD spectroscopy

8

2D NMR spectroscopy (introduction)

9

2D NMR spectroscopy (COSY)

10

2D NMR spectroscopy (HSQC)

11

2D NMR spectroscopy (HMBC)

41

12

2D NMR spectroscopy (NOESY)

13

Mass spectroscopy

14

Chemical derivatization (1)15Chemical derivatization (2)422016年度／Academic Year
2年通年／Two years whole year

曜日・校時／Day・Period

開講期間／Class period

2016/09/27～2018/9/30

必修選択／Required/Elective class

必修／required

単位数(一般/編入/留学)／Credits
16.0(general/admission/overseas)

時間割コード／Time schedule code

201655082010C7

科目番号／Subject code

科目ナンバリングコード／Numbering Code

BMMP66912796

学期／Semester

55082010

Experiment Biomedical Sciences：Natural Product Chemistry／Experiment Biomedical Sciences

授業科目名／Subject
編集担当教員／Professor in charge ofputting together the course syllabus

田中隆／Tanaka Takashi, 齋藤

授業担当教員名（科目責任者）／Professor in charge of the subject

田中隆／Tanaka Takashi

授業担当教員名（オムニバス科目等）／Professor(s)田中隆／Tanaka Takashi, 齋藤

科目分類／Class type

Experiment Biomedical Sciences

対象年次／Year

1, 2

教室／Class room
対象学生（クラス等）

他／Others 0

嘉朗／Saito Yoshiro, 松尾

洋介／Matsuo Yosuke

嘉朗／Saito Yoshiro, 松尾

洋介／Matsuo Yosuke

講義形態／Class Form

実験／Experiment〔薬学〕各担当教員研究室／Laboratory/Object Student

Master course

担当教員Eメールアドレス/E‑mail addresst‑tanaka@nagasaki‑u.ac.jp

担当教員研究室/Laboratory

Natural Product Chemistry

担当教員TEL/Tel

819‑2432

Any time (Please make appointment by E‑mail ）担当教員オフィスアワー/Office hours
授業の概要及び位置づけ/Course Outline and To achieve the isolation and structure determination of natural products, isolating
methods and instrumentalanalysis should be studied.
Objectives

授業到達目標/Goal

The students should learn the experimental method and skill, to achieve their ability to
pursue their target bythemselves.

授業方法（学習指導法）/Method

During the experiment, student are consulted freely, and directed.

授業内容/Class outline/Con

Practice of extraction, separation, purification, and structure determination of natural
products.

キーワード/Key word

natural product, terpene, flavonoid, phenol, polyphenol

教科書・教材・参考書/Textbook,Teachingmaterial,and Reference book

English journals, English‑Japanese and Japanese‑English dictionaries,
Biochemical encyclopedia, Scientific and Chemical encyclopedia, Handbook ofAnalytical Chemistry, Handbook of Chemistry.

成績評価の方法・基準等/Evaluation

Understanding ability of English paper 50%, writing ability of English paper 50%

受講要件（履修条件）/Requirements

none

アクセシビリティ/Accessibility

In order to ensure equal educational opportunities for all students, Nagasaki University
strives to remove societal barriers that may interfere with academic activities, and toprovide reasonable accommodations as necessary and appropriate. If you have any questions
or concerns regarding reasonable accommodations or other support in this class, pleasefeel free to talk to the instructor (contact information above), or contact the Student
Accessibility Office.
Student Accessibility Office contact information（TEL）095‑819‑2006（FAX）095‑819‑2948（E‑MAIL）support@ml.nagasaki‑u.ac.jp

備考（URL）/Remarks(URL)
学生へのメッセージ/Message for students
授業計画詳細／Course Schedule
回(日時)／Time(date and time)

授業内容／Contents

1

Selection of targeted plant or other natural resources

2

HPLC and TLC analysis of plants.

3

Extraction,

4

Fractionation

5

Column chromatography

6

Column chromatography

7

Column chromatography

8

Purification of the natural compounds

9

Purification of the natural compoundswith solvent partitioning

43

10

Chemical derivatization of compounds

11

Chemical and phisical properties of natural compounds

12

Structure determination of the natural products

13

Structure determination of the natural products

14

Structure confirmation of the natural products

15

Preparation of paper

16

Preparation of paper

44

2016年度／Academic Year
2年通年／Two years whole year

曜日・校時／Day・Period

開講期間／Class period

2016/09/27～2018/9/30

必修選択／Required/Elective class

必修／required

単位数(一般/編入/留学)／Credits
4.0(general/admission/overseas)

時間割コード／Time schedule code

201655082000A8

科目番号／Subject code

科目ナンバリングコード／Numbering Code

BMMP66812796

授業科目名／Subject

Exercise Biomedical Sciences：Medicinal Plant Biochemistry／Exercise Biomedical Sciences

編集担当教員／Professor in charge ofputting together the course syllabus

山田

耕史／Yamada Koji

授業担当教員名（科目責任者）／Professor in charge of the subject

山田

耕史／Yamada Koji

授業担当教員名（オムニバス科目等）／Professor(s)山田

耕史／Yamada Koji

科目分類／Class type

Exercise Biomedical Sciences

対象年次／Year

1, 2

学期／Semester

教室／Class room
対象学生（クラス等）

講義形態／Class Form

他／Others 055082000

演習／Seminar〔薬学〕各担当教員研究室／Laboratory/Object Student

Master course

担当教員Eメールアドレス/E‑mail address

kyamada@nagasaki‑u.ac.jp

担当教員研究室/Laboratory

Medicinal Plant Biochemistry

担当教員TEL/Tel

095‑819‑2462

担当教員オフィスアワー/Office hours
授業の概要及び位置づけ/Course Outline andObjectives
授業到達目標/Goal

Monday 13:00‑14:00

授業方法（学習指導法）/Method

Oral presentation with academic documents and discussions

授業内容/Class outline/Con

In this seminar, students must read the scientific English papers for your research
themes, and your research data should be summarized in English.

It is aimed to acquire the writing ability of English article for the publishing of theexperimental papers as a scientific researcher.
It is the goal to write logically the scientific articles without grammatical errors.

キーワード/Key word
教科書・教材・参考書/Textbook,Teachingmaterial,and Reference book
成績評価の方法・基準等/Evaluation

Article search, English paper, Presentation

受講要件（履修条件）/Requirements

none

アクセシビリティ/Accessibility

English journals, JACS, JOC, JNP etc
Understanding ability of English paper 50%, writing ability of English paper 50%
In order to ensure equal educational opportunities for all students, Nagasaki University
strives to remove societal barriers that may interfere with academic activities, and toprovide reasonable accommodations as necessary and appropriate. If you have any questions
or concerns regarding reasonable accommodations or other support in this class, pleasefeel free to talk to the instructor (contact information above), or contact the Student
Accessibility Office.
Student Accessibility Office contact information（TEL）095‑819‑2006（FAX）095‑819‑2948（E‑MAIL）support@ml.nagasaki‑u.ac.jp

備考（URL）/Remarks(URL)
学生へのメッセージ/Message for students

Specialized instruction. Editing and logical consideration of the data, and in advanceplanning of the research experiment.

授業計画詳細／Course Schedule
回(日時)／Time(date and time)

授業内容／Contents

1stLecture how to write an English paper.

2nd

Lecture how to write an English paper.

3rd

Explain one English paper related to your research, and discuss on their data.

4th

Explain one English paper related to your research, and discuss on their data.

5th

Explain one English paper related to your research, and discuss on their data.

6th

Explain one English paper related to your research, and discuss on their data.

7th

Explain one English paper related to your research, and discuss on their data.

8th

Explain one English paper related to your research, and discuss on their data.

pth

Explain one English paper related to your research, and discuss on their data.

10th

Explain one English paper related to your research, and discuss on their data.

45

11th

Explain one English paper related to your research, and discuss on their data.

12th

Explain one English paper related to your research, and discuss on their data.

13th

Explain one English paper related to your research, and discuss on their data.

14th

Explain one English paper related to your research, and discuss on their data.

15th

Explain one English paper related to your research, and discuss on their data.

46

2016年度／Academic Year
2年通年／Two years whole year

曜日・校時／Day・Period

開講期間／Class period

2016/09/27～2018/9/30

必修選択／Required/Elective class

必修／required

単位数(一般/編入/留学)／Credits
16.0(general/admission/overseas)

時間割コード／Time schedule code

201655082010C8

科目番号／Subject code

科目ナンバリングコード／Numbering Code

BMMP66912796

授業科目名／Subject

Experiment Biomedical Sciences：Medicinal Plant Biochemistry／Experiment Biomedical
Sciences

編集担当教員／Professor in charge ofputting together the course syllabus

山田

耕史／Yamada Koji

授業担当教員名（科目責任者）／Professor in charge of the subject

山田

耕史／Yamada Koji

授業担当教員名（オムニバス科目等）／Professor(s)山田

耕史／Yamada Koji

科目分類／Class type

Experiment Biomedical Sciences

対象年次／Year

1, 2

学期／Semester

教室／Class room
対象学生（クラス等）

講義形態／Class Form

他／Others 055082010

実験／Experiment〔薬学〕各担当教員研究室／Laboratory/Object Student

Master course

担当教員Eメールアドレス/E‑mail address

kyamada@nagasaki‑u.ac.jp

担当教員研究室/Laboratory

Medicinal Plant Biochemistry

担当教員TEL/Tel

095‑819‑2462

Monday 13:00‑14:00
担当教員オフィスアワー/Office hours
授業の概要及び位置づけ/Course Outline and It is aimed to study how to perform the experiments of scientific theme, and to make thescientific paper in English
Objectives

授業到達目標/Goal
授業方法（学習指導法）/Method

授業内容/Class outline/Con

It is the goal to independently make the experiment plan for the research, and to publish
the research data into an academic journal.
Carrying out individual experiments, getting the personal direction on each theme, anddiscussion about the data.
The bioactive constituents obtained from marine organisms are isolated, and thosestructures are elucidated, and detailed bioactivities are studied, to develop the new
medicine material of the marine origin. In this Experiment, the research on bioactive
constituent is done for that.

キーワード/Key word
教科書・教材・参考書/Textbook,Teachingmaterial,and Reference book
成績評価の方法・基準等/Evaluation

Article, scientific English paper, Presentation

受講要件（履修条件）/Requirements

none

アクセシビリティ/Accessibility

Scientific journals:

ACS, JOC, JNP etc,

Database:

SciFinder Scholar

Complete English paper and its thesis 100%
In order to ensure equal educational opportunities for all students, Nagasaki University
strives to remove societal barriers that may interfere with academic activities, and toprovide reasonable accommodations as necessary and appropriate. If you have any questions
or concerns regarding reasonable accommodations or other support in this class, pleasefeel free to talk to the instructor (contact information above), or contact the Student
Accessibility Office.
Student Accessibility Office contact information（TEL）095‑819‑2006（FAX）095‑819‑2948（E‑MAIL）support@ml.nagasaki‑u.ac.jp

備考（URL）/Remarks(URL)
学生へのメッセージ/Message for students

Specialized instruction. Editing and logical consideration of the data, and in advanceplanning of the research experiment.

授業計画詳細／Course Schedule
回(日時)／Time(date and time)

授業内容／Contents

1stMake the strategy for the research based on the aim

2nd

Do the experiments

3rd

Do the experiments

4th

Do the experiments

5th

Do the experiments

6thAnalyze the experimental results, and solve problems.

47

2016年度／Academic Year
2年通年／Two years whole year

曜日・校時／Day・Period

開講期間／Class period

2016/09/27～2018/9/30

必修選択／Required/Elective class

必修／required

単位数(一般/編入/留学)／Credits
4.0(general/admission/overseas)

時間割コード／Time schedule code

201655082000A9

科目番号／Subject code

科目ナンバリングコード／Numbering Code

BMMP66812796

授業科目名／Subject

Exercise Biomedical Sciences：Structure Analysis for Chemicals／Exercise Biomedical
Sciences

編集担当教員／Professor in charge ofputting together the course syllabus

真木

俊英(長崎大学産学官連携戦略本部)

授業担当教員名（科目責任者）／Professor in charge of the subject

真木

俊英(長崎大学産学官連携戦略本部)

授業担当教員名（オムニバス科目等）／Professor(s)真木

俊英(長崎大学産学官連携戦略本部)

科目分類／Class type

Exercise Biomedical Sciences

対象年次／Year

1年,2年

学期／Semester

教室／Class room
対象学生（クラス等）

講義形態／Class Form

他/Others

55082000

演習／Seminar〔薬学〕各担当教員研究室／Laboratory/Object Student

Master course

担当教員Eメールアドレス/E‑mail address

maki@nagasaki‑u.ac.jp

担当教員研究室/Laboratory

Structure Analysis for Chemicals

担当教員TEL/Tel

095‑819‑2465

担当教員オフィスアワー/Office hours

Mon. ‑ Fri. 12:00 ‑ 13:00

Searching, understanding, and analysis of current publications about organic chemistry
and pharmaceutical sciences.
授業の概要及び位置づけ/Course Outline andAnalysis of research reports based on their background, experiments, and results.
Objectives
Discussion about contents of research and future subjects.

授業到達目標/Goal

授業方法（学習指導法）/Method

授業内容/Class outline/Con

Capability to search the target paper
Skill for efficient use technology of a database
Capability of understanding of specialized contents
The original paper relevant to research is chosen from a scholarly journal, and a seminar
reports.
The paper is read and comprehended.
i) Capability to read a special academic journal and to understand the contentsii) Capability to carry out reproducibility test by reading and dispelling the method ofan experimentiii) Capability to investigate the results of a paper and to use for own research.

キーワード/Key word
教科書・教材・参考書/Textbook,Teachingmaterial,and Reference book
成績評価の方法・基準等/Evaluation

database, search, summarization, presentation, discussion

受講要件（履修条件）/Requirements

None

アクセシビリティ/Accessibility

In order to ensure equal educational opportunities for all students, Nagasaki University
strives to remove societal barriers that may interfere with academic activities, and toprovide reasonable accommodations as necessary and appropriate. If you have any questions
or concerns regarding reasonable accommodations or other support in this class, pleasefeel free to talk to the instructor (contact information above), or contact the Student
Accessibility Office.
Student Accessibility Office contact information（TEL）095‑819‑2006（FAX）095‑819‑2948（E‑MAIL）support@ml.nagasaki‑u.ac.jp

Journals for organic chemistry (JACS, JOC, Org.Letter, Tetrahedron etc.)
Skill for search 20%, selection of paper 20%, presentation 20%, and the discussion 40%

備考（URL）/Remarks(URL)
学生へのメッセージ/Message for students

48

7th

Do the experiments.

8th

Do the experiments.

9th

Do the experiments.

10th

Do the experiments.

11th

Do the experiments.

12th

Do the experiments.

13th

Summarize experimental results, report, and discuss.

14th

Present the research data at an academic meeting.

15th

Publish the research results in a scientific English journal.

49

2016年度／Academic Year
2年通年／Two years whole year

曜日・校時／Day・Period

開講期間／Class period

2016/09/27～2018/9/30

必修選択／Required/Elective class

必修／required

単位数(一般/編入/留学)／Credits
16.0(general/admission/overseas)

時間割コード／Time schedule code

201655082010C9

科目番号／Subject code

科目ナンバリングコード／Numbering Code

BMMP66912796

授業科目名／Subject

Experiment Biomedical Sciences：Structure Analysis for Chemicals／Experiment Biomedical
Sciences

編集担当教員／Professor in charge ofputting together the course syllabus

真木

俊英／Maki Toshihide

授業担当教員名（科目責任者）／Professor in charge of the subject

真木

俊英／Maki Toshihide

授業担当教員名（オムニバス科目等）／Professor(s)真木

俊英／Maki Toshihide

科目分類／Class type

Experiment Biomedical Sciences

対象年次／Year

1, 2

学期／Semester

教室／Class room
対象学生（クラス等）

講義形態／Class Form

他／Others 055082010

実験／Experiment〔薬学〕各担当教員研究室／Laboratory/Object Student

Master course

担当教員Eメールアドレス/E‑mail address

maki@nagasaki‑u.ac.jp

担当教員研究室/Laboratory

Structure Analysis for Chemicals

担当教員TEL/Tel

095‑819‑2465

担当教員オフィスアワー/Office hours

Mon. ‑ Fri. 12:00 ‑ 13:00

Searching, understanding, and analysis of current publications about organic chemistry
and pharmaceutical sciences.
授業の概要及び位置づけ/Course Outline andAnalysis of research reports based on their background, experiments, and results.
Objectives
Discussion about contents of research and future subjects.

授業到達目標/Goal

授業方法（学習指導法）/Method

授業内容/Class outline/Con

Capability to search the target paper
Skill for efficient use technology of a database
Capability of understanding of specialized contents
The original paper relevant to research is chosen from a scholarly journal, and a seminar
reports.
The paper is read and comprehended.
i) Capability to read a special academic journal and to understand the contentsii) Capability to carry out reproducibility test by reading and dispelling the method ofan experimentiii) Capability to investigate the results of a paper and to use for own research.

キーワード/Key word
教科書・教材・参考書/Textbook,Teachingmaterial,and Reference book
成績評価の方法・基準等/Evaluation

database, search, summarization, presentation, discussion

受講要件（履修条件）/Requirements

None

アクセシビリティ/Accessibility

In order to ensure equal educational opportunities for all students, Nagasaki University
strives to remove societal barriers that may interfere with academic activities, and toprovide reasonable accommodations as necessary and appropriate. If you have any questions
or concerns regarding reasonable accommodations or other support in this class, pleasefeel free to talk to the instructor (contact information above), or contact the Student
Accessibility Office.
Student Accessibility Office contact information（TEL）095‑819‑2006（FAX）095‑819‑2948（E‑MAIL）support@ml.nagasaki‑u.ac.jp

Journals for organic chemistry (JACS, JOC, Org.Letter, Tetrahedron etc.)
Skill for search 20%, selection of paper 20%, presentation 20%, and the discussion 40%

備考（URL）/Remarks(URL)
学生へのメッセージ/Message for students

50

2016年度／Academic Year
2年通年／Two years whole year

曜日・校時／Day・Period

開講期間／Class period

2016/09/27～2018/9/30

必修選択／Required/Elective class

必修／required

単位数(一般/編入/留学)／Credits
4.0(general/admission/overseas)

時間割コード／Time schedule code

201655082000B0

科目番号／Subject code

科目ナンバリングコード／Numbering Code

BMMP66812796

授業科目名／Subject

Exercise Biomedical Sciences：Chemistry of Biofunctional
Sciences

編集担当教員／Professor in charge ofputting together the course syllabus

甲斐雅亮／Kai Masaaki, 椛島

授業担当教員名（科目責任者）／Professor in charge of the subject

甲斐雅亮／Kai Masaaki

授業担当教員名（オムニバス科目等）／Professor(s)甲斐雅亮／Kai Masaaki, 椛島

科目分類／Class type

Exercise Biomedical Sciences

対象年次／Year

1, 2

学期／Semester

教室／Class room
対象学生（クラス等）

他／Others 055082000
Molecules／Exercise Biomedical

力／Kabashima Tsutomu, 柴田

孝之／Shibata Takayuki

力／Kabashima Tsutomu, 柴田

孝之／Shibata Takayuki

講義形態／Class Form

演習／Seminar〔薬学〕各担当教員研究室／Laboratory/Object Student

Master course

担当教員Eメールアドレス/E‑mail address

ms‑kai@nagasaki‑u.ac.jp

担当教員研究室/Laboratory

Chemistry of Biofunctional Molecules

担当教員TEL/Tel

095‑819‑2438

担当教員オフィスアワー/Office hours
授業の概要及び位置づけ/Course Outline andObjectives
授業到達目標/Goal

12:00‑18:00

授業方法（学習指導法）/Method
授業内容/Class outline/Con

To learn how to demonstrate about contents of scientific papers, and individual
experimental data.
To attain ability of solution about individual research problems.
Comprehension of various experimental data in scientific papers related to your research,and presentation of your experimental data.
Demonstration of a scientific paper related to your research and of your experimental
data each time.

キーワード/Key word
教科書・教材・参考書/Textbook,Teachingmaterial,and Reference book
成績評価の方法・基準等/Evaluation

Presentation

受講要件（履修条件）/Requirements

none

アクセシビリティ/Accessibility

In order to ensure equal educational opportunities for all students, Nagasaki University
strives to remove societal barriers that may interfere with academic activities, and toprovide reasonable accommodations as necessary and appropriate. If you have any questions
or concerns regarding reasonable accommodations or other support in this class, pleasefeel free to talk to the instructor (contact information above), or contact the Student
Accessibility Office.
Student Accessibility Office contact information（TEL）095‑819‑2006（FAX）095‑819‑2948（E‑MAIL）support@ml.nagasaki‑u.ac.jp

Electronic dictionary, English‑Japanese dictionary, Internet information
Presentation ability(30%), Discussion ability(30%), Aggressiveness(40%)

備考（URL）/Remarks(URL)
学生へのメッセージ/Message for students
授業計画詳細／Course Schedule
回(日時)／Time(date and time)

授業内容／Contents

1st

Present an English paper, and discuss about its data (1)2ndPresent an English paper, and discuss about its data (2)3rdIntroduce experimental data, and discuss about them (1)4thIntroduce experimental data, and discuss about them (2)5thStudy how to solve research problems and get a conclusion.

6th

Repeat above plans

51

2016年度／Academic Year
2年通年／Two years whole year

曜日・校時／Day・Period

開講期間／Class period

2016/09/27～2018/9/30

必修選択／Required/Elective class

必修／required

単位数(一般/編入/留学)／Credits
16.0(general/admission/overseas)

時間割コード／Time schedule code

201655082010D0

科目番号／Subject code

科目ナンバリングコード／Numbering Code

BMMP66912796

授業科目名／Subject

Experiment Biomedical Sciences：Chemistry of Biofunctional
Biomedical Sciences

Molecules／Experiment

編集担当教員／Professor in charge ofputting together the course syllabus

甲斐雅亮／Kai Masaaki, 椛島

力／Kabashima Tsutomu, 柴田

孝之／Shibata Takayuki

授業担当教員名（科目責任者）／Professor in charge of the subject

甲斐雅亮／Kai Masaaki

授業担当教員名（オムニバス科目等）／Professor(s)甲斐雅亮／Kai Masaaki, 椛島

力／Kabashima Tsutomu, 柴田

孝之／Shibata Takayuki

科目分類／Class type

Experiment Biomedical Sciences

対象年次／Year

1, 2

学期／Semester

教室／Class room
対象学生（クラス等）

講義形態／Class Form

他／Others 055082010

実験／Experiment〔薬学〕各担当教員研究室／Laboratory/Object Student

Master course

担当教員Eメールアドレス/E‑mail address

ms‑kai@nagasaki‑u.ac.jp

担当教員研究室/Laboratory

Chemistry of Biofunctional Molecules

担当教員TEL/Tel

095‑819‑2438

12:00‑18:00
担当教員オフィスアワー/Office hours
授業の概要及び位置づけ/Course Outline andTo learn how to carry out experimets of scientific theme, and to get the positive data.
Objectives
To publish your research data as academic papers and to attain a matter degree.
授業到達目標/Goal

授業方法（学習指導法）/Method

Research of your scientific theme.

授業内容/Class outline/Con

Research one of the following scientific subjects:
1)genomics and proteomics, 2)optical organic reagents, 3)DNA analysis, 4)protein
interaction, and 5)expression regulation of gene.

キーワード/Key word
教科書・教材・参考書/Textbook,Teachingmaterial,and Reference book
成績評価の方法・基準等/Evaluation

Experiment

Reports

受講要件（履修条件）/Requirements

アクセシビリティ/Accessibility

In order to ensure equal educational opportunities for all students, Nagasaki University
strives to remove societal barriers that may interfere with academic activities, and toprovide reasonable accommodations as necessary and appropriate. If you have any questions
or concerns regarding reasonable accommodations or other support in this class, pleasefeel free to talk to the instructor (contact information above), or contact the Student
Accessibility Office.
Student Accessibility Office contact information（TEL）095‑819‑2006（FAX）095‑819‑2948（E‑MAIL）support@ml.nagasaki‑u.ac.jp

備考（URL）/Remarks(URL)
学生へのメッセージ/Message for students
授業計画詳細／Course Schedule
回(日時)／Time(date and time)

授業内容／Contents

1stGetting information about individual themes

2nd

Making the plan for the research

3rdExperiments

4thReport of individual experimental data

5th

Repeat above plans

52

2016年度／Academic Year
2年通年／Two years whole year

曜日・校時／Day・Period

開講期間／Class period

2016/09/27～2018/9/30

必修選択／Required/Elective class

必修／required

単位数(一般/編入/留学)／Credits
4.0(general/admission/overseas)

時間割コード／Time schedule code

201655082000B1

科目番号／Subject code

科目ナンバリングコード／Numbering Code

BMMP66812796

授業科目名／Subject

Exercise Biomedical Sciences：Hygienic Chemistry／Exercise Biomedical Sciences

編集担当教員／Professor in charge ofputting together the course syllabus

中山

守雄／Nakayama Morio, 淵上

中山

守雄／Nakayama Morio

授業担当教員名（オムニバス科目等）／Professor(s)中山

守雄／Nakayama Morio, 淵上

科目分類／Class type

Exercise Biomedical Sciences

対象年次／Year

1, 2

学期／Semester

授業担当教員名（科目責任者）／Professor in charge of the subject

教室／Class room
対象学生（クラス等）

他／Others 055082000

剛志／Fuchigami Takeshi, 吉田

さくら／Yoshida Sakura

剛志／Fuchigami Takeshi, 吉田

さくら／Yoshida Sakura

講義形態／Class Form

演習／Seminar〔薬学〕各担当教員研究室／Laboratory/Object Student

Master course

担当教員Eメールアドレス/E‑mail address

morio@nagasaki‑u.ac.jp

担当教員研究室/Laboratory

Hygienic Chemistry

担当教員TEL/Tel

095‑819‑2442

担当教員オフィスアワー/Office hours
授業の概要及び位置づけ/Course Outline andObjectives
授業到達目標/Goal

Monday−Friday 0:20−0:50 p.m. or by appointment

授業方法（学習指導法）/Method

Oral presentation with academic documents and discussions

授業内容/Class outline/Con

In this seminar, students must read the scientific English papers for your research
themes, and your research data should be summarized in English.

キーワード/Key word

Article search, English paper, Presentation.

教科書・教材・参考書/Textbook,Teachingmaterial,and Reference book

English journals, English‑Japanese and Japanese‑English dictionaries,
Biochemical encyclopedia, Scientific and Chemical encyclopedia, Handbook of Analytical
Chemistry,
Handbook of Chemistry.

成績評価の方法・基準等/Evaluation

Understanding ability of English paper 50%, writing ability of English paper 50%

受講要件（履修条件）/Requirements

Nothing

アクセシビリティ/Accessibility

It is aimed to acquire the writing ability of English article for the publishing of the experimental papers as ascientific researcher
It is the goal to write logically the scientific articles without grammatical errors

In order to ensure equal educational opportunities for all students, Nagasaki University
strives to remove societal barriers that may interfere with academic activities, and toprovide reasonable accommodations as necessary and appropriate. If you have any questions
or concerns regarding reasonable accommodations or other support in this class, pleasefeel free to talk to the instructor (contact information above), or contact the Student
Accessibility Office.
Student Accessibility Office contact information（TEL）095‑819‑2006（FAX）095‑819‑2948（E‑MAIL）support@ml.nagasaki‑u.ac.jp

備考（URL）/Remarks(URL)
学生へのメッセージ/Message for students

Preparation of the English paper is required in advance.

授業計画詳細／Course Schedule
回(日時)／Time(date and time)

授業内容／Contents

1stLecture how to write an English paper

2ndLecture how to write an English paper

3rd

Lecture how to write an English paper

4thLecture how to write an English paper

5thLecture how to write an English paper

6thLecture how to write an English paper

7thLecture how to write an English paper

8thLecture how to write an English paper

9thMake a plan to write an English paper : Arrangement of whole contents.

53

10th

Write the English article of theIntroduction

11th

Write the English article of theResults

and making the Figures and Tables.

12th

Write the English article of theResults.

13th

Write the English article of theDiscussion

.

14th

Write the English article of theDiscussion

.

15th

Write the complete English article with the references.

54

and

Materials and Methods.

2016年度／Academic Year
2年通年／Two years whole year

曜日・校時／Day・Period

開講期間／Class period

2016/09/27～2018/9/30

必修選択／Required/Elective class

必修／required

単位数(一般/編入/留学)／Credits
16.0(general/admission/overseas)

時間割コード／Time schedule code

201655082010D1

科目番号／Subject code

科目ナンバリングコード／Numbering Code

BMMP66912796

授業科目名／Subject

Experiment Biomedical Sciences：Hygienic Chemistry／Experiment Biomedical Sciences

編集担当教員／Professor in charge ofputting together the course syllabus

中山

守雄／Nakayama Morio, 淵上

中山

守雄／Nakayama Morio

授業担当教員名（オムニバス科目等）／Professor(s)中山

守雄／Nakayama Morio, 淵上

科目分類／Class type

Experiment Biomedical Sciences

対象年次／Year

1, 2

学期／Semester

授業担当教員名（科目責任者）／Professor in charge of the subject

教室／Class room
対象学生（クラス等）

他／Others 055082010

剛志／Fuchigami Takeshi, 吉田

さくら／Yoshida Sakura

剛志／Fuchigami Takeshi, 吉田

さくら／Yoshida Sakura

講義形態／Class Form

実験／Experiment〔薬学〕各担当教員研究室／Laboratory/Object Student

Master course

担当教員Eメールアドレス/E‑mail address

morio@nagasaki‑u.ac.jp

担当教員研究室/Laboratory

Hygienic Chemistry

担当教員TEL/Tel

095‑819‑2441

Monday−Friday 0:20−0:50 p.m. or by appointment
担当教員オフィスアワー/Office hours
授業の概要及び位置づけ/Course Outline and
It is aimed to study how to perform the experiments of scientific theme.
Objectives
It is the goal to independently make the experiment plan for the research
授業到達目標/Goal

授業方法（学習指導法）/Method

授業内容/Class outline/Con

Carrying out individual experiments, getting the personal direction on each theme, anddiscussion about the data.
Research one of the following scientific subjects: 1) trace essential elements inbiological system, 2)
selenium as nutrient, 3) biomembrane mimetic materials, 4) 99mTc radiopharmaceuticals,and 5) amyloid imaging probe

キーワード/Key word
教科書・教材・参考書/Textbook,Teachingmaterial,and Reference book
成績評価の方法・基準等/Evaluation

Strategy, Research, Presentation.

受講要件（履修条件）/Requirements

Nothing

アクセシビリティ/Accessibility

Scientific journals, Database
Laboratory work (50%), Presentation and communication skill (50%),
In order to ensure equal educational opportunities for all students, Nagasaki University
strives to remove societal barriers that may interfere with academic activities, and toprovide reasonable accommodations as necessary and appropriate. If you have any questions
or concerns regarding reasonable accommodations or other support in this class, pleasefeel free to talk to the instructor (contact information above), or contact the Student
Accessibility Office.
Student Accessibility Office contact information（TEL）095‑819‑2006（FAX）095‑819‑2948（E‑MAIL）support@ml.nagasaki‑u.ac.jp

備考（URL）/Remarks(URL)
学生へのメッセージ/Message for students

Editing and logical consideration of the data, and in advance planning of theresearch experiment

授業計画詳細／Course Schedule
回(日時)／Time(date and time)

授業内容／Contents

1stMake the strategy for the research.

2nd

Do the experiments

3rdAnalyze the experimental results, and solve problems.

4th

Summarize experimental results, report, and discuss.

5th

Present the research data at an academic meeting55

2016年度／Academic Year
2年通年／Two years whole year

曜日・校時／Day・Period

開講期間／Class period

2016/09/27～2018/9/30

必修選択／Required/Elective class

必修／required

単位数(一般/編入/留学)／Credits
4.0(general/admission/overseas)

時間割コード／Time schedule code

201655082000B2

科目番号／Subject code

科目ナンバリングコード／Numbering Code

BMMP66812796

授業科目名／Subject

Exercise Biomedical Sciences：Analytical Chemistry／Exercise Biomedical Sciences

編集担当教員／Professor in charge ofputting together the course syllabus

黒田直敬／Naotaka Kuroda, 岸川

授業担当教員名（科目責任者）／Professor in charge of the subject

黒田直敬／Naotaka Kuroda

授業担当教員名（オムニバス科目等）／Professor(s)黒田直敬／Naotaka Kuroda, 岸川

科目分類／Class type

Exercise Biomedical Sciences

対象年次／Year

1, 2

学期／Semester

教室／Class room
対象学生（クラス等）

他／Others 055082000

直哉／Kishikawa Naoya

直哉／Kishikawa Naoya

講義形態／Class Form

演習／Seminar〔薬学〕各担当教員研究室／Laboratory/Object Student

Master course

担当教員Eメールアドレス/E‑mail addressn‑kuro@nagasaki‑u.ac.jp

担当教員研究室/Laboratory

Analytical Chemistry, 5th floor

担当教員TEL/Tel

Ext. 2894

担当教員オフィスアワー/Office hours

AM 10:30‑PM 18:00
This course provides instruction and experience in organizing and presenting oral

授業の概要及び位置づけ/Course Outline andpresentations on a particular topic of interest regarding individual research project
Objectives
from literature search.
授業到達目標/Goal
授業方法（学習指導法）/Method

授業内容/Class outline/Con

キーワード/Key word
教科書・教材・参考書/Textbook,Teachingmaterial,and Reference book
成績評価の方法・基準等/Evaluation

Student will develop skills in scientific literature retrieval and oral presentation ofscientific information from literature search.
Student will summarize the contents of the literatures that relate to the individual
research project, explain, ask and answer the questions.
This course will provide how to do a literature search, to evaluate scientificinformation, to summarize the appropriate information, to develop and propose a novel
research idea, to convey that information in an oral presentation, and to further developscientific writing skills.
1. Effective use of the library and other information resources including Internet
2. Finding appropriate information utilizing the primary literature.
3. Finding and evaluating information utilizing secondary sources such as the Internet
including SciFinder Scholar and Medline
4. Preparing PowerPoint slides using effective information
5. Oral presentation of appropriate information from literature search, and ask andanswer the questions
6. Discussions of the contents of oral presentation with faculty members in laboratory
and students

Appropriate literature from the journals of analytical chemistry
Method of achievement evaluation/active participation (60%), presentation skill (20%),
ask and answer the questions (20%)

受講要件（履修条件）/Requirements

アクセシビリティ/Accessibility

In order to ensure equal educational opportunities for all students, Nagasaki University
strives to remove societal barriers that may interfere with academic activities, and toprovide reasonable accommodations as necessary and appropriate. If you have any questions
or concerns regarding reasonable accommodations or other support in this class, pleasefeel free to talk to the instructor (contact information above), or contact the Student
Accessibility Office.
Student Accessibility Office contact information（TEL）095‑819‑2006（FAX）095‑819‑2948（E‑MAIL）support@ml.nagasaki‑u.ac.jp

備考（URL）/Remarks(URL)
学生へのメッセージ/Message for students

56

2016年度／Academic Year
2年通年／Two years whole year

曜日・校時／Day・Period

開講期間／Class period

2016/09/27～2018/9/30

必修選択／Required/Elective class

必修／required

単位数(一般/編入/留学)／Credits
16.0(general/admission/overseas)

時間割コード／Time schedule code

201655082010D2

科目番号／Subject code

科目ナンバリングコード／Numbering Code

BMMP66912796

授業科目名／Subject

Experiment Biomedical Sciences：Analytical Chemistry／Experiment Biomedical Sciences

編集担当教員／Professor in charge ofputting together the course syllabus

黒田直敬／Naotaka Kuroda, 岸川

授業担当教員名（科目責任者）／Professor in charge of the subject

黒田直敬／Naotaka Kuroda

授業担当教員名（オムニバス科目等）／Professor(s)黒田直敬／Naotaka Kuroda, 岸川

科目分類／Class type

Experiment Biomedical Sciences

対象年次／Year

1, 2

学期／Semester

教室／Class room
対象学生（クラス等）

他／Others 055082010

直哉／Kishikawa Naoya

直哉／Kishikawa Naoya

講義形態／Class Form

実験／Experiment〔薬学〕各担当教員研究室／Laboratory/Object Student

Master course

担当教員Eメールアドレス/E‑mail addressn‑kuro@nagasaki‑u.ac.jp

担当教員研究室/Laboratory

Analytical Chemistry, 5th floor

担当教員TEL/Tel

Ext. 2894

AM 10:30‑PM 18:00
担当教員オフィスアワー/Office hours
授業の概要及び位置づけ/Course Outline and To learn experimental methods and skills used by analytical chemists, and to learn how toeffectively present scientific results and to further develop scientific writing skills.
Objectives

授業到達目標/Goal

授業方法（学習指導法）/Method

授業内容/Class outline/Con

キーワード/Key word
教科書・教材・参考書/Textbook,Teachingmaterial,and Reference book
成績評価の方法・基準等/Evaluation

Student will develop skills in 1) planning investigations, 2) operation of analyticalequipments, 3) collection and treatment of experimental data, 4) oral presentation ofscientific research, 5) writing scientific reports, 6) developing scientific thinking andproblem‑solving techniques.
Student will acquire knowledge and skills on experiments relating to analytical chemistry
through laboratory work and report writing skills.
To accomplish the goals, experiments have been designed to covers literature search,
proper and safe operation of laboratory equipment, data collecting and report writing.
1. Scientific literature retrieval on individual research project
2. Understanding of special techniques and instruments for individual research project
3. Planning and conducting experiments
4. Records and treatment of data obtained from the experimental protocols
5. Using a computer as a tool in writing, drawing chemical structures and data analysis
to communicate scientific information
6. Communicating effectively the results of experimental results with faculty members inlaboratory and students
7. Presentation of research results at appropriate academic conference
8. Writing scientific reports

Appropriate literature on individual research projectLaboratory work (50%), presentation and communication skill (10%), reports (30%),
presentation at academic conference (10%)

受講要件（履修条件）/Requirements

アクセシビリティ/Accessibility

In order to ensure equal educational opportunities for all students, Nagasaki University
strives to remove societal barriers that may interfere with academic activities, and toprovide reasonable accommodations as necessary and appropriate. If you have any questions
or concerns regarding reasonable accommodations or other support in this class, pleasefeel free to talk to the instructor (contact information above), or contact the Student
Accessibility Office.
Student Accessibility Office contact information（TEL）095‑819‑2006（FAX）095‑819‑2948（E‑MAIL）support@ml.nagasaki‑u.ac.jp

備考（URL）/Remarks(URL)
学生へのメッセージ/Message for students57

2016年度／Academic Year
2年通年／Two years whole year

曜日・校時／Day・Period

開講期間／Class period

2016/09/27～2018/9/30

必修選択／Required/Elective class

必修／required

単位数(一般/編入/留学)／Credits
4.0(general/admission/overseas)

時間割コード／Time schedule code

201655082000B3

科目番号／Subject code

科目ナンバリングコード／Numbering Code

BMMP66812796

授業科目名／Subject

Exercise Biomedical Sciences：Pharmacotherapeutics／Exercise Biomedical Sciences

編集担当教員／Professor in charge ofputting together the course syllabus

塚元

和弘／Tsukamoto Kazuhiro, 近藤

授業担当教員名（科目責任者）／Professor in charge of the subject

塚元

和弘／Tsukamoto Kazuhiro

授業担当教員名（オムニバス科目等）／Professor(s)塚元

和弘／Tsukamoto Kazuhiro, 近藤

科目分類／Class type

Exercise Biomedical Sciences

対象年次／Year

1, 2

学期／Semester

教室／Class room
対象学生（クラス等）

他／Others 055082000

新二／Kondo Shinji

新二／Kondo Shinji

講義形態／Class Form

演習／Seminar〔薬学〕各担当教員研究室／Laboratory/Object Student

Master course

担当教員Eメールアドレス/E‑mail address

ktsuka@nagasaki‑u.ac.jp

担当教員研究室/Laboratory

Department of Pharmacotherapeutics

担当教員TEL/Tel

095‑819‑8573

Monday‑Friday 9:00‑17:00
担当教員オフィスアワー/Office hours
授業の概要及び位置づけ/Course Outline andTo teach clinical and molecular genetics
Objectives

授業到達目標/Goal

To understand the methods to identify the disease‑susceptible and drug‑responsible genes
for multifactorial disorders, and an application to nucleic acids‑based diagnosis

授業方法（学習指導法）/Method

Lecture using PowerPoint slides and printed documents

授業内容/Class outline/Con

キーワード/Key word
教科書・教材・参考書/Textbook,Teachingmaterial,and Reference book
成績評価の方法・基準等/Evaluation

The personalized medicine composes the nucleic acids‑based diagnosis and genome‑based
gene discovery including the susceptible genes for diseases and the drug‑responsible
genes. The association study using genetic polymorphic markers is a strong tool toidentify the disease‑susceptible and drug‑responsible genes for multifactorial disorders.
genetic polymorphisms, association study, multifactorial disorders, nucleic acids‑based
diagnosis
none
brief examination at each class (40%) and report (60%)

受講要件（履修条件）/Requirements

アクセシビリティ/Accessibility

In order to ensure equal educational opportunities for all students, Nagasaki University
strives to remove societal barriers that may interfere with academic activities, and toprovide reasonable accommodations as necessary and appropriate. If you have any questions
or concerns regarding reasonable accommodations or other support in this class, pleasefeel free to talk to the instructor (contact information above), or contact the Student
Accessibility Office.
Student Accessibility Office contact information（TEL）095‑819‑2006（FAX）095‑819‑2948（E‑MAIL）support@ml.nagasaki‑u.ac.jp

備考（URL）/Remarks(URL)
学生へのメッセージ/Message for students
授業計画詳細／Course Schedule
回(日時)／Time(date and time)

授業内容／Contents

1stClinical human genetics I

2ndClinical human genetics II

3rd

Molecular human genetics I

4th

Molecular human genetics II

5thGenetic polymorphisms and detecting techniques

6thMultifactorial disorders and association study

7th

Identification of disorder‑susceptible and drug‑responsible genes

8th

Nucleic acids‑based diagnosis

58

2016年度／Academic Year
2年通年／Two years whole year

曜日・校時／Day・Period

開講期間／Class period

2016/09/27～2018/9/30

必修選択／Required/Elective class

必修／required

単位数(一般/編入/留学)／Credits
16.0(general/admission/overseas)

時間割コード／Time schedule code

201655082010D3

科目番号／Subject code

科目ナンバリングコード／Numbering Code

BMMP66912796

授業科目名／Subject

Experiment Biomedical Sciences：Pharmacotherapeutics／Experiment Biomedical Sciences

編集担当教員／Professor in charge ofputting together the course syllabus

塚元

和弘／Tsukamoto Kazuhiro, 近藤

授業担当教員名（科目責任者）／Professor in charge of the subject

塚元

和弘／Tsukamoto Kazuhiro

授業担当教員名（オムニバス科目等）／Professor(s)塚元

和弘／Tsukamoto Kazuhiro, 近藤

科目分類／Class type

Experiment Biomedical Sciences

対象年次／Year

1, 2

学期／Semester

教室／Class room
対象学生（クラス等）

他／Others 055082010

新二／Kondo Shinji

新二／Kondo Shinji

講義形態／Class Form

実験／Experiment〔薬学〕各担当教員研究室／Laboratory/Object Student

Master course

担当教員Eメールアドレス/E‑mail address

ktsuka@nagasaki‑u.ac.jp

担当教員研究室/Laboratory

Department of Pharmacotherapeutics

担当教員TEL/Tel

095‑819‑8573

Monday‑Friday 9:00‑17:00
担当教員オフィスアワー/Office hours
授業の概要及び位置づけ/Course Outline and To identify the disease‑susceptible genes or drug‑responsible genes by candidate gene‑based association study
Objectives

授業到達目標/Goal
授業方法（学習指導法）/Method

授業内容/Class outline/Con

キーワード/Key word
教科書・教材・参考書/Textbook,Teachingmaterial,and Reference book
成績評価の方法・基準等/Evaluation

To learn molecular genetics techniques and skills in both bioinformatics and statisticalanalyses, as well as to understand the concept of methodology on association study,
especially case‑control study
Performance of molecular genetics, bioinformatics, pharmacogenomics, and case‑control
study
The personalized medicine composes the nucleic acids‑based diagnosis and genome‑based
gene discovery including the susceptible genes for diseases and the drug‑responsible
genes. The association study using genetic polymorphic markers is a strong tool toidentify the disease‑susceptible and drug‑responsible genes for multifactorial disorders.
genetic polymorphisms, bioinformatics, association study, disease‑susceptibility, drug
responsibility
None
Masters dissertation (100%)

受講要件（履修条件）/Requirements

アクセシビリティ/Accessibility

In order to ensure equal educational opportunities for all students, Nagasaki University
strives to remove societal barriers that may interfere with academic activities, and toprovide reasonable accommodations as necessary and appropriate. If you have any questions
or concerns regarding reasonable accommodations or other support in this class, pleasefeel free to talk to the instructor (contact information above), or contact the Student
Accessibility Office.
Student Accessibility Office contact information（TEL）095‑819‑2006（FAX）095‑819‑2948（E‑MAIL）support@ml.nagasaki‑u.ac.jp

備考（URL）/Remarks(URL)
学生へのメッセージ/Message for students
授業計画詳細／Course Schedule
回(日時)／Time(date and time)

授業内容／Contents

1st

DNA and RNA extraction

2nd

Selection of candidate genes for the disease‑susceptibility or drug responsibility

3rdGetting information on genetic polymorphisms of candidate genes from genome database(bioinformatics)

4th

Analyses of genetic polymorphisms of candidate genes (1)5thAnalyses of genetic polymorphisms of candidate genes (2)6thAnalyses of genetic polymorphisms of candidate genes (3)

59

7th

Statistical analyses

8th

Discussion on the results

9thWriting a manuscript

10th

Submission of a master60

s dissertation

2016年度／Academic Year
2年通年／Two years whole year

曜日・校時／Day・Period

開講期間／Class period

2016/09/27～2018/9/30

必修選択／Required/Elective class

必修／required

単位数(一般/編入/留学)／Credits
4.0(general/admission/overseas)

時間割コード／Time schedule code

201655082000B4

科目番号／Subject code

科目ナンバリングコード／Numbering Code

BMMP66812796

授業科目名／Subject

Exercise Biomedical Sciences：Pharmaceutical Informatics／Exercise Biomedical Sciences

編集担当教員／Professor in charge ofputting together the course syllabus

川上茂／Kawakami Shigeru, 渕上

授業担当教員名（科目責任者）／Professor in charge of the subject

川上茂／Kawakami Shigeru

授業担当教員名（オムニバス科目等）／Professor(s)川上茂／Kawakami Shigeru, 渕上

科目分類／Class type

Exercise Biomedical Sciences

対象年次／Year

1, 2

学期／Semester

教室／Class room
対象学生（クラス等）

他／Others 0, 日／Sun 0

55082000

由貴／Fuchigami Yuki, 萩森

政頼

由貴／Fuchigami Yuki, 萩森

政頼

講義形態／Class Form

演習／Seminar〔薬学〕各担当教員研究室／Laboratory/Object Student

Master course

担当教員Eメールアドレス/E‑mail address

skawakam@nagasaki‑u.ac.jp

担当教員研究室/Laboratory

Pharmaceutical Informatics

担当教員TEL/Tel

095‑819‑8563

担当教員オフィスアワー/Office hours

9:00‑17:00

This course provides fundamental skills in organizing and presentaing document on aparticular topic regarding pharmaceutical informatics from scientific papers.【薬学教育モ
授業の概要及び位置づけ/Course Outline andデル・コアカリキュラム一般目標】A 全学年を通して：ヒューマニズムについて学ぶ A(2)医療の担
Objectives
い手としてのこころ構え、C16 製剤化のサイエンス (3)DDS（Drug Delivery System: 薬物送達システム）、C17 医薬品の開発と生産(1)医薬品開発と生産の流れ、(3)バイオ医薬品とゲノム情報
To understand the content of the scientific papers and find the relashionship between
scientific papers and own research.薬学教育モデル・コアカリキュラム到達目標を含む項目：A‑
授業到達目標/Goal(2)【研究活動に求められるこころ構え】、C16‑(3)【DDSの必要性】、【ターゲティング】、【その他のDDS】 C17‑(1)【医薬品市場と開発すべき医薬品】、C17‑(3)【遺伝子治療】

授業方法（学習指導法）/Method

Student summerizes the scientific papers, and discusses content with laboratory members.

授業内容/Class outline/Con

1st: Searching the scientific papers related to own research from Pubmed
2nd: Preparing a document for oral presentation
3rd: Oral presentation and discussion(1)4th: Oral presentation and discussion(2)5th: Oral presentation and discussion(3)6th: Oral presentation and discussion(4)7th: Oral presentation and discussion(5)8th: Oral presentation and discussion(6)9th: Oral presentation and discussion(7)10th: Oral presentation and discussion(8)11th: Oral presentation and discussion(9)12th: Oral presentation and discussion(10)13th: Oral presentation and discussion(11)14th: Oral presentation and discussion(12)15th: Oral presentation and discussion(13)キーワード/Key word
教科書・教材・参考書/Textbook,Teachingmaterial,and Reference book
成績評価の方法・基準等/Evaluation

Pharmaceutial Informatics, Presentation Skill

受講要件（履修条件）/Requirements

None

アクセシビリティ/Accessibility

In order to ensure equal educational opportunities for all students, Nagasaki University
strives to remove societal barriers that may interfere with academic activities, and toprovide reasonable accommdations as necessary and appropriate. If you have any questions
or concerns regarding reasonable accommodations or other support in this class, pleasefeel free to talk to the instructor (contact information above), or contact the Student
Accessibility Office.
Student Accessibility Office contact information(TEL) 095‑819‑2006 (FAX) 095‑819‑24948(E‑mail) support@ml.nagasaki‑u.ac.jp

Ability of presentation (70%), Ability of discussion (30%)

備考（URL）/Remarks(URL)61

学生へのメッセージ/Message for students

None

62

2016年度／Academic Year
2年通年／Two years whole year

曜日・校時／Day・Period

開講期間／Class period

2016/09/27～2018/9/30

必修選択／Required/Elective class

必修／required

単位数(一般/編入/留学)／Credits
16.0(general/admission/overseas)

時間割コード／Time schedule code

201655082010D4

科目番号／Subject code

科目ナンバリングコード／Numbering Code

BMMP66912796

授業科目名／Subject

Experiment Biomedical Sciences：Pharmaceutical Informatics／Experiment Biomedical
Sciences

編集担当教員／Professor in charge ofputting together the course syllabus

川上茂／Kawakami Shigeru, 渕上

授業担当教員名（科目責任者）／Professor in charge of the subject

川上茂／Kawakami Shigeru

授業担当教員名（オムニバス科目等）／Professor(s)川上茂／Kawakami Shigeru, 渕上

科目分類／Class type

Experiment Biomedical Sciences

対象年次／Year

1, 2

学期／Semester

教室／Class room
対象学生（クラス等）

他／Others 055082010

由貴／Fuchigami Yuki, 萩森

政頼

由貴／Fuchigami Yuki, 萩森

政頼

講義形態／Class Form

実験／Experiment〔薬学〕各担当教員研究室／Laboratory/Object Student

Master course

担当教員Eメールアドレス/E‑mail address

skawakam@nagasaki‑u.ac.jp

担当教員研究室/Laboratory

Pharmaceutical Informatics

担当教員TEL/Tel

095‑819‑8563

担当教員オフィスアワー/Office hours

9:00‑17:00

This course provides fundamental skills in organizing and presentaing document on aparticular topic regarding pharmaceutical informatics from scientific papers.【薬学教育モ
授業の概要及び位置づけ/Course Outline andデル・コアカリキュラム一般目標】A 全学年を通して：ヒューマニズムについて学ぶ A(2)医療の担
Objectives
い手としてのこころ構え、C16 製剤化のサイエンス (3)DDS（Drug Delivery System: 薬物送達システム）、C17 医薬品の開発と生産(1)医薬品開発と生産の流れ、(3)バイオ医薬品とゲノム情報
To understand the content of the scientific papers and find the relashionship between
scientific papers and own research.薬学教育モデル・コアカリキュラム到達目標を含む項目：A‑
授業到達目標/Goal(2)【研究活動に求められるこころ構え】、C16‑(3)【DDSの必要性】、【ターゲティング】、【その他のDDS】 C17‑(1)【医薬品市場と開発すべき医薬品】、C17‑(3)【遺伝子治療】

授業方法（学習指導法）/Method

Student summerizes the scientific papers, and discusses content with laboratory members.

授業内容/Class outline/Con

1st: Searching the scientific papers related to own research from Pubmed
2nd: Preparing a document for oral presentation
3rd: Oral presentation and discussion(1)4th: Oral presentation and discussion(2)5th: Oral presentation and discussion(3)6th: Oral presentation and discussion(4)7th: Oral presentation and discussion(5)8th: Oral presentation and discussion(6)9th: Oral presentation and discussion(7)10th: Oral presentation and discussion(8)11th: Oral presentation and discussion(9)12th: Oral presentation and discussion(10)13th: Oral presentation and discussion(11)14th: Oral presentation and discussion(12)15th: Oral presentation and discussion(13)キーワード/Key word
教科書・教材・参考書/Textbook,Teachingmaterial,and Reference book
成績評価の方法・基準等/Evaluation

Pharmaceutial Informatics, Presentation Skill

受講要件（履修条件）/Requirements

None

アクセシビリティ/Accessibility

In order to ensure equal educational opportunities for all students, Nagasaki University
strives to remove societal barriers that may interfere with academic activities, and toprovide reasonable accommdations as necessary and appropriate. If you have any questions
or concerns regarding reasonable accommodations or other support in this class, pleasefeel free to talk to the instructor (contact information above), or contact the Student
Accessibility Office.
Student Accessibility Office contact information(TEL) 095‑819‑2006 (FAX) 095‑819‑24948(E‑mail) support@ml.nagasaki‑u.ac.jp

Ability of presentation (70%), Ability of discussion (30%)

63備考（URL）/Remarks(URL)
学生へのメッセージ/Message for students

None

64

2016年度／Academic Year
2年通年／Two years whole year

曜日・校時／Day・Period

開講期間／Class period

2016/09/27～2018/9/30

必修選択／Required/Elective class

必修／required

単位数(一般/編入/留学)／Credits
4.0(general/admission/overseas)

時間割コード／Time schedule code

201655082000B5

科目番号／Subject code

科目ナンバリングコード／Numbering Code

BMMP66812796

授業科目名／Subject

Exercise Biomedical Sciences：Pharmaceutics／Exercise Biomedical Sciences

編集担当教員／Professor in charge ofputting together the course syllabus

西田孝洋／Nishida Koyo, 麓

授業担当教員名（科目責任者）／Professor in charge of the subject

西田孝洋／Nishida Koyo

授業担当教員名（オムニバス科目等）／Professor(s)西田

孝洋／Nishida Koyo, 麓

科目分類／Class type

Exercise Biomedical Sciences

対象年次／Year

1, 2

学期／Semester

教室／Class room
対象学生（クラス等）

他／Others 055082000

伸太郎／Fumoto Shintaro, 宮元敬天／Hirotaka Miyamoto

伸太郎／Fumoto Shintaro, 宮元敬天／Hirotaka Miyamoto

講義形態／Class Form

演習／Seminar〔薬学〕各担当教員研究室／Laboratory/Object Student

Master course

担当教員Eメールアドレス/E‑mail addresskoyo‑n@nagasaki‑u.ac.jp

担当教員研究室/Laboratory

Pharmaceutics

担当教員TEL/Tel

095‑819‑8566

担当教員オフィスアワー/Office hours

Thursday and Friday 16:00‑18:00（LACSで予定を確認すること）, Accept any question by e-mailAim/

授業の概要及び位置づけ/Course Outline and The aim of this subject is to acquire abilities to understand scientific paper(s),summarize background, method and results, and make a presentation of the paper(s).
Objectives

授業到達目標/Goal

授業方法（学習指導法）/Method
授業内容/Class outline/Con

Goal/
To acquire abilities for objective critique and creative research, students should
precisely understand positioning of findings in scientific papers at the area of relevant
study, be able to point out problems to be elucidated, and consider concrete solution.
Method/Searching and understanding scientific papers, questions and answers.
Understanding scientific papers written in English. By making a presentation of thepapers, students can obtain recent information and acquire the ability to use scientificキーワード/Key word
教科書・教材・参考書/Textbook,Teachingmaterial,and Reference book
成績評価の方法・基準等/Evaluation

Searching scientific papers

受講要件（履修条件）/Requirements

none

アクセシビリティ/Accessibility

In order to ensure equal educational opportunities for all students, Nagasaki University
strives to remove societal barriers that may interfere with academic activities, and toprovide reasonable accommodations as necessary and appropriate. If you have any questions
or concerns regarding reasonable accommodations or other support in this class, pleasefeel free to talk to the instructor (contact information above), or contact the Student
Accessibility Office.
Student Accessibility Office contact information（TEL）095‑819‑2006 （FAX）095‑819‑2948（E‑MAIL）support@ml.nagasaki‑u.ac.jp

備考（URL）/Remarks(URL)

http://www.ph.nagasaki‑u.ac.jp/

学生へのメッセージ/Message for students

Preparation studies for reading scientific papers and replying to questions are required.

Scientific journals written in English
Ability to understand scientific papers 50%

Ability for questions and answers 50%

授業計画詳細／Course Schedule
回(日時)／Time(date and time)

授業内容／Contents

1stAttending a lecture for database and searching method of scientific papers.

2nd

Attending a lecture how to read experimental methods, results and discussion.

3rd

Selecting a scientific paper, making a presentation of summary of the study, and replying
to questions (1)

65

4th

Selecting a scientific paper, making a presentation of summary of the study, and replying
to questions (2)5thSelecting a scientific paper, making a presentation of summary of the study, and replying
to questions (3)6thSelecting a scientific paper, making a presentation of summary of the study, and replying
to questions (4)7thSelecting a scientific paper, making a presentation of summary of the study, and replying
to questions (5)8thSelecting a scientific paper, making a presentation of summary of the study, and replying
to questions (6)9thSelecting a scientific paper, making a presentation of summary of the study, and replying
to questions (7)10thSelecting a scientific paper, making a presentation of summary of the study, and replying
to questions (8)11thSelecting a scientific paper, making a presentation of summary of the study, and replying
to questions (9)12thSelecting a scientific paper, making a presentation of summary of the study, and replying
to questions (10)13thSelecting a scientific paper, making a presentation of summary of the study, and replying
to questions (11)14thSelecting a scientific paper, making a presentation of summary of the study, and replying
to questions (12)15thSelecting a scientific paper, making a presentation of summary of the study, and replying
to questions (13)662016年度／Academic Year
2年通年／Two years whole year

曜日・校時／Day・Period

開講期間／Class period

2016/09/27～2018/9/30

必修選択／Required/Elective class

必修／required

単位数(一般/編入/留学)／Credits
16.0(general/admission/overseas)

時間割コード／Time schedule code

201655082010D5

科目番号／Subject code

科目ナンバリングコード／Numbering Code

BMMP66912796

授業科目名／Subject

Experiment Biomedical Sciences：Pharmaceutics／Experiment Biomedical Sciences

編集担当教員／Professor in charge ofputting together the course syllabus

西田孝洋／Nishida Koyo, 麓

授業担当教員名（科目責任者）／Professor in charge of the subject

西田孝洋／Nishida Koyo

授業担当教員名（オムニバス科目等）／Professor(s)西田

孝洋／Nishida Koyo, 麓

科目分類／Class type

Experiment Biomedical Sciences

対象年次／Year

1, 2

学期／Semester

教室／Class room
対象学生（クラス等）

他／Others 055082010

伸太郎／Fumoto Shintaro

伸太郎／Fumoto Shintaro

講義形態／Class Form

実験／Experiment〔薬学〕各担当教員研究室／Laboratory/Object Student

Master course

担当教員Eメールアドレス/E‑mail addresskoyo‑n@nagasaki‑u.ac.jp

担当教員研究室/Laboratory

Pharmaceutics

担当教員TEL/Tel

095‑819‑8566

担当教員オフィスアワー/Office hours

Thursday and Friday 16:00-18:00（LACSで予定を確認すること）, Accept any question by e-mailAim/
It is required for researchers in the clinical pharmacy to develop novel drug delivery
授業の概要及び位置づけ/Course Outline andsystem delivering drugs to specific target site. Researchers also should individually
Objectives
resolve problems of the research. The aim of this subject is to acquire these abilities
through experiments and discussion.
Goal/
The goal of this subject is to develop administration methods and formulations for
授業到達目標/Goaldelivering drugs to specific organ. Student will report findings in academic conference
and write scientific paper(s) for submitting to journal.
Method/
授業方法（学習指導法）/Method
Scheduling and performing experiments, Writing scientific papers.
Students will experiment about drug delivery system delivering drugs to specific organ.
For this purpose, absorption of drugs from organ surface, in vivo disposition of drugs,
授業内容/Class outline/Con
administration methods, administration preparations, species differences, animal scale‑up, and formulations for future clinical application will be investigated.

キーワード/Key word
教科書・教材・参考書/Textbook,Teachingmaterial,and Reference book
成績評価の方法・基準等/Evaluation

DDS

受講要件（履修条件）/Requirements

Scientific English

アクセシビリティ/Accessibility

In order to ensure equal educational opportunities for all students, Nagasaki University
strives to remove societal barriers that may interfere with academic activities, and toprovide reasonable accommodations as necessary and appropriate. If you have any questions
or concerns regarding reasonable accommodations or other support in this class, pleasefeel free to talk to the instructor (contact information above), or contact the Student
Accessibility Office.
Student Accessibility Office contact information（TEL）095‑819‑2006 （FAX）095‑819‑2948（E‑MAIL）support@ml.nagasaki‑u.ac.jp

備考（URL）/Remarks(URL)

http://www.ph.nagasaki‑u.ac.jp/

学生へのメッセージ/Message for students

none

Scientific journals written in English
50％writing paper, 50% experiment

授業計画詳細／Course Schedule
回(日時)／Time(date and time)
第1回
第2回

授業内容／Contents
Study about recent researches in drug delivery system.
Scheduling experiments. Comprehending unknown points by understanding publishedinformation.

67

第3回
第4回
第5回
第6回

Deliberating administration methods for drug delivery system.
Deliberating administration preparations for drug delivery system.
Discussion of experimental plan on seminar of Department of Pharmaceutics.
Study about disposition of drugs after administration onto organ surface.

第7回

Study about experimental method utilizing glass‑made cylindrical diffusion cell forinvestigation of absorption from organ surface.

第8回

Study about experimental condition (administration dose, volume) for organ surface
application of drugs.

第9回
第10回
第11回
第12回
第13回

Study about formulations for administration of drugs onto organ surface.
Discussion of findings in midterm conference of Department of Pharmaceutics.
Study about formulations which are applicable for clinical use.
Study about species differences and animal scale‑up.
Discussion of findings in final conference of Department of Pharmaceutics.
Writing draft in English.

第14回
第15回

Completing scientific paper and submitting it to a scientific journal.

68