PRESS RELEASE
1-6-2 Marunouchi, Chiyoda-ku, Tokyo 100-8246 Japan

June 24, 2024

Zeon announces the market release of a new cell culture microplate with superior quality stability andconvenience, contributing to accelerating drug discovery and development
Zeon Corporation
Zeon Corporation (Zeon; head office: Chiyoda-ku, Tokyo; President and CEO: Tetsuya Toyoshima) has succeeded in developing a newmicroplate for culturing cells that uses Zeon’s proprietary cyclo olefin polymers (COPs; product names: ZEONEX® and ZEONOR®)
and a proprietary coating material. The new product will be released in July 2024 as an addition to the lineup offered by Aurora
Microplates, an American business acquired by Zeon in 2022.
COPs, well known for their unique properties such as low autofluorescence, high light transmittance, low biomolecules adsorption,and low impurities, are already widely used in lab equipment associated with biochemical analysis, including containers for biologics,
analytical devices, and microplates. The newly developed cell culture microplate will deliver these outstanding properties along withexcellent quality stability and convenience.
The new product will be introduced at the upcoming pharmaceutical research and development exhibition PharmaLab EXPO Tokyo,
to be held at the Tokyo Big Sight during INTERPHEX WEEK Tokyo from June 26 to 28.

〇 New Product: Cell Culture Microplate with Proprietary CoatingAdvantages(1) Quality stability:

Minimal lot-to-lot variation, with uniform surface condition maintained by application ofproprietary coating material(2) Excellent shelf life:
Can be stored at room temperature for up to one year(3) Improved convenience: Can be used immediately with little or no need for any coating

Neurite (µm/cell)

Tends to elongate neurites further than PDL coating

MAP2-stained image

Comparison of neurite length

Analysis method
MAP2-stained cells were photographed with an image
cytometer and quantified using analytical software

Zeon has identified healthcare and life sciences as key areas for new business exploration under its STAGE 30 Medium-Term Business
Plan, which lays out the Group’s goals for 2030. The company is working to expand applications related to these area for COP, including
collaboration with Aurora Microplates. The launch of the new product is intended to fully demonstrate COP’s excellent properties
while also accelerating the pace of drug discovery and development by adding new functions that are not available in other products.

1PRESS RELEASE
1-6-2 Marunouchi, Chiyoda-ku, Tokyo 100-8246 Japan

Outline of exhibit
Dates: Wednesday, June 26–Friday, June 28, 2024
Location: Tokyo Big Sight, East Hall 7 (Booth 52-12)
Click on the banner to access the official website.
Zeon will exhibit other products in addition to the new one.
Dates: Wednesday, June 26–Thursday, June 27, 2024
Location: Congress Center Basel Hall 4.1 (Booth 76)
Click on the banner to access the official website.
Zeon will exhibit other products in addition to the new one.

About microplates offered by Aurora Microplates
Aurora Microplates provides high-performance and high-precision microplates made of COP, featuring superior properties compared
to conventional microplates, such as optimal clarity, thermal stability, biocompatibility, low auto-fluorescence, flatness, and chemicalresistance.

Characteristics of Aurora Microplates✔ Optimal clarity• Sharper images✔ Low auto-fluorescence• Reduced recording time

✔ Extreme flatness of plate and well surfaces

In keeping with its name, derived from the Greek words “geo” (Earth) and “eon” (eternity), Zeon will contribute to environmental
sustainability along with safe and comfortable living by providing innovative technologies, products, and services.

For more information, contact:
Department of Corporate Communications, Corporate Sustainability Division, Zeon Corporation
Phone: +81-3-3216-2747

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