News Release

March 22, 2023
KANEKA CORPORATIONBACCHUS BIO INNOVATION CO., LTD
JGC HOLDINGS CORPORATIONSHIMADZU CORPORATION“Development of Polymer Synthesis Technology by Microorganisms using CO2
as Direct Raw Material” selected as a NEDO Green Innovation Fund Project”
Kaneka Corporation (Headquarters: Minato-ku, Tokyo; President: Minoru Tanaka; hereinafter"Kaneka"), Bacchus Bio innovation Co., Ltd (Headquarters: Kobe-city, Hyogo; President: Mikio
Tanji; hereinafter "Bacchus"), JGC Holdings Corporation (Headquarters: Yokohama-city
Kanagawa; Chairman and CEO: Masayuki Sato; hereinafter "JGC HD"), and Shimadzu
Corporation (Headquarters: Kyoto-city, Kyoto; President: Yasunori Yamamoto; hereinafter"Shimadzu") have announced that the proposal of a joint project,” Development of Polymer
Synthesis Technology by microorganisms using CO2 as direct raw material(hereinafterreferred to as ‘the Project’)” had been selected by the "Green Innovation Fund Project*1 /Promotion of Carbon Recycling Using CO2 from Biomanufacturing Technology as a Direct Raw
Material” as a planned implementation sponsored by the New Energy and Industrial
Technology Development Organization (NEDO).
This project will contribute to the realization of carbon recycling in the "Green Growth Strategy
Through Achieving Carbon Neutrality in 2050" formulated by the Ministry of Economy, Tradeand Industry with related ministries and agencies on December 25, 2020 (revised on June 18,2021). The goal of the project is to realize recycling-oriented biomanufacturing technology that
does not depend on fossil resources by developing microorganisms that produce biodegradable
polymers from CO2 and developing production process technology, combining the knowledge andtechnology that the four companies have cultivated over the years.

News Release
During the project period (FY2023 to FY2030), the following three themes will be addressed.
-Establishment of a gas fermentation biofoundry*2 using CO2 as a raw material (Bacchusand Shimadzu)-

Development and improvement of biopolymer-producing microorganisms (Kaneka)-

Development and demonstration of production technology using microorganisms capable ofproducing substances from CO2 (Kaneka, JGC HD, Shimadzu)

The following chart outlines the development and collaboration of the four companies in thisproject.

< Kaneka >Kaneka is the first company in the world to successfully commercialize KANEKA BiodegradablePolymer Green PlanetTM ("Green Planet"), which is produced by microorganisms from vegetable
oil and other raw materials. In this project, based on the synthetic microbiology and polymer
production, processing technologies it has cultivated to date, Kaneka will develop new
microorganisms that produce Green Planet directly from CO2, and will also launch a semicommercial plant to conduct production demonstration for Green Planet industrialization. Inaddition, we will lead this project as the managing company.
< Bacchus >Bacchus is a data-driven biofoundry company. Bacchus aims to drastically shorten the breedingtime of smart cells*3 by upgrading the breeding platform consolidating its proprietary
technologies. By utilizing its own digital technology, Bacchus will design cells optimized for gas
fermentation and create a variety of species. In addition, they will introduce and utilize datafrom a high-throughput evaluation system jointly developed with Shimadzu, and aim to build
an "Integrated Biofoundry*4" that will provide one-stop service from microbial breeding toprocess development with JGC HD.

News Release< JGC HD >JGC HD has a profound knowledge of the safe gas handling of gases including hydrogen gas andprocess scale-up cultivated through its EPC (Engineering, Procurement, and Construction)business in the oil and gas fields, as well as in optimized culture tank design technology in thelife science field. In this project, JGC HD will develop and scale-up a safe handling system formixed gases containing CO2, H2, and O2 and a highly efficient gas fermentation process inaddition to establishing an “Integrated Biofoundry” with Bacchus which will provide a one-stop
service from microbial breeding to process development.
< Shimadzu >Shimadzu, with the aim of solving social issues, has accumulated a variety of know-how by
providing analytical measurement and robotics technologies to a wide range of fields and data
analysis technologies using AI-based systems. In this project, Shimadzu will work on thedevelopment of high-speed productivity evaluation technology, which is indispensable for theconstruction of a biofoundry. Shimadzu will also develop an evaluation system to measure gas
fermentation in the semi-commercial plant which is to be constructed as part of the project andsupport safe and highly efficient fermentation.
*1. A project to support companies and others working on management issues toward Japan's"Carbon Neutrality in 2050," from R&D and demonstration to social implementation byFY2030. The program covers 14 fields: transportation/manufacturing-related industries
including carbon recycling/materials industries, energy-related industries, and home/officerelated industries.
*2. Biofoundry: Microorganism development platform that creates microorganisms withdesigned functions to efficiently produce useful substances*3. Smart cell: A cell that is highly designed and has an enhanced ability to efficiently produce
the desired substance*4. Integrated Biofoundry: A one-stop biomanufacturing platform that provides everything frommicrobial breeding to process development