ポスター

Poster＊ 学生発表賞応募演題＊ Student Presentation Award Application Poster
A. 蛋白質:機能・構造・物性・計測・工学／A. Protein General
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全原子分子動力学法による維持メチル化酵素(Dnmt1)とその捕因子の動態解析
Theoretical Analyses on Dynamic Properties of DNA methyltransferase 1 and its Cofactors Basedon All-atom Molecular Dynamics Simulations
Takunori Yasuda1, Yasuteru Shigeta2, Ryuhei Harada2 (1College of Biological Sciences, University ofTsukuba, 2Center for Computational Sciences, University of Tsukuba, 3Center for Computational Sciences,
University of Tsukuba)
3D−RISM 理論を応用した溶液中におけるペプチドの構造揺らぎの解析
Analysis of structural fluctuations of a small peptide in the solution phase by means of 3D-RISM
theoryMasatake Sugita (Sch. Computing, Tokyo Tech)
細菌べん毛形成開始するために 34 個集まってリングになる 2 回膜貫通タンパク質 FliF の N 末端・
C 末端細胞質領域欠損体の解析
Analysis of the cytoplasmic region-deficient mutants of double-transmembrane protein FliF whichforms a MS-ring in flagellar formation
Seiji Kojima1, Mitsuki Kajino1, Keiichi Hirano1, Yuna Inoue1, Tatsuro Nishikino2, Hiroyuki Terashima1,
Michio Homma1 (1Nagoya Univ, Sch Sci, Div Biol Sci, 2Osaka Univ, Ins Protein Res)
Pin1 の変異体 C113A と C113S の構造解析
Structural analysis of Pin1 mutants C113A And C113S
Teikichi Ikura, Nobutoshi Ito (Med. Res. Inst., Tokyo Med. Dent. Univ.)
Similarity and difference between substrate analogue-induced and spontaneous folding ofstaphylococcal nuclease
Yujiro Mori1, Saho Segawa2, Kosuke Maki1 (1Grad. Sch. Sci., Nagoya Univ., 2Sch. Sci., Nagoya Univ.)
タンパク質の複合体の界面の相互作用のデータベース解析
Database analysis of protein-protein interaction
Wataru Sagawa, George Chikenji (Dept. Appl. Phys., Nagoya Univ.)
Cross-seeding of human and bovine insulin amyloid fibrils induces stepwise conformationaltransition via intermediate states
Keisuke Yuzu1, Naoki Yamamoto2, Masahiro Noji3, Masatomo So3, Yuji Goto3, Tetsushi Iwasaki1,4,
Motonari Tsubaki1, Eri Chatani1 (1Grad. Sch. Sci., Kobe Univ., 2Fac. Med., Jichi Med. Univ., 3Inst. ProteinRes., Osaka Univ., 4Biosignal Res. Center, Kobe Univ.)
低温電子顕微鏡画像を記述する連続関数の計算法：マニフォールドラーニングによる研究
A Computational Method for Constructing a Continuous Function Describing Cryo-Electron
Microscopy Data: A Study using a Manifold Learning
Ryota Kojima, Takashi Yoshidome (Dep. of Appl. Phys., Tohoku Univ.)
Unguided Binding MD of Protein-Protein Complexes by PPI-ColDock
Kazuhiro Takemura, Akio Kitao (Sch. LST, Tokyo Tech)tRNA 硫黄修飾酵素における鉄硫黄クラスター構造と酵素活性の相関解析
Correlation between structures of iron-sulfur clusters and enzymatic activity in tRNA thiolation
enzymes
Masato Ishizaka1, Minghao Chen2, Shun Narai1, Masaki Horitani3, Yoshikazu Tanaka4, Min Yao1,2(1Grad. Sch. Life Sci., Hokkaido Univ., 2Facul. Adv. Life Sch., Hokkaido Univ., 3Facul. Agr., Saga Univ.,
4Grad. Sci. Life Sci., Tohoku Univ.)
Sampling large-scale motions in proteins using a coarse-grained multi-basin Go modelAi Shinobu1, Chigusa Kobayashi1, Yasuhiro Matsunaga2, Yuji Sugita1 (1RIKEN, 2Saitama Univ.)– S52 –

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Visualization of translational GTPase factor-pool formed on the archaeal ribosomal P-stalk by HSAFM
Hirotatsu Imai1, Toshio Uchiumi2, Noriyuki Kodera1 (1WPI-NanoLSI, Kanazawa Univ., 2Faculty of
Science, Niigata Univ.)
NMR 解析によるシニョリンとその変異体の立体構造の決定
Determination of structures of chignolin and its mutant by NMR analysis
Shumpei Koroku1, Ayori Mitsutake2, Yutaka Maruyama3, Koh Takeuchi4 (1Meiji University, 2Meiji
University, 3RIKEN, 4AIST)
高速 AFM を用いた磁性細菌の細胞骨格結合タンパク質 MamJ の機能解析
Functional analyses of magnetotactic bacterial cytoskeletal binding protein MamJ using highspeed AFM
Takumi Saito1, Yosuke Kikuchi2, Yoshihiro Fukumori3, Azuma Taoka2,3 (1Graduate School of Natural
Science and Technology, Kanazawa University, 2Institute of Science and Engineering, Kanazawa
University, 3Nano Life Science Institute (NanoLSI), Kanazawa University)
18 残基チオエーテル結合環状ペプチド群のシミュレーションデータの解析
Analysis of Molecular Dynamics Simulations of 18-residue Thioether Cyclic Peptides
Daiki Noguchi (Meiji university graduate school)
グラフ理論に基づくタンパク質立体構造の位相解析への VOLTES 法の応用
Application of VOLTES to topological analyses of protein structures based on graph theory
Anri Terabayashi, Kyousuke Sakata, Toshitaka Shoji, Masaki Kojima (Sch. Life Sci., Tokyo Univ. Pharm.
Life Sci.)
The molecular basis for the nucleotide selectivity of the ε subunit from bacterial F-type ATPsynthases
Alexander Krah1,2, Roland G. Huber1, Duncan G. G. McMillan3, Peter J. Bond1,4 (1Bioinformatics Institute(BII), 2Korea Institute for Advanced Study, 3TU Delft, 4Department of Biological Sciences, National
University of Singapore)
Free Energy Calculations of HIV-1 Protease Binding Indinavir and Its Drug-Resistant Mutant
Masahiko Taguchi1, Ryo Oyama2, Masahiro Kaneso2, Shigehiko Hayashi2 (1Inst. Quant. Life Sci., QST,
2Grad. Sch. Sci., Kyoto Univ.)
メタゲノムデータベース由来 PET 加水分解酵素の耐熱性および活性の改良
Improvement of thermostability and catalytic activity of a PET degrading enzyme derived frommetagenome database
Akihiko Nakamura1, Naoya Kobayashi2, Takahiro Kosugi2, Rie Koga2, Nobuyasu Koga2,3, Ryota Iino2,3(1Shizuoka Univ., 2Inst. Mol. Sci., 3SOKENDAI)
心筋カルシウムチャネル Cav1.2 と薬剤間の結合自由エネルギー計算
Calculation of the binding free energy between the Cav1.2 calcium channel and drugs
Tatsuki Negami, Tohru Terada (Grad. Sch. Agr. Life Sci., Univ. Tokyo)
標的空間を 2,3,4 次元とした Dimensional Scaling 法によるフラグメント間相互作用エネルギー行
列解析
Analysis of inter fragment interaction energy by Dimensinal Scaling method in 2,3,4 byDimensional as the target space
Yuki Abe, Masanori Yamanaka (Univ.Nihon)
蛋白質内部で水素結合を形成する荷電残基が示す強力な安定化効果についての熱力学的評価
The thermodynamic characterization of the strong stabilization effect by a buried and charged
residue forming hydrogen bonds
Hiroaki Sato, Akiko Nakazawa, Kohei Yamamoto, Shun-ichi Kidokoro (Dept. Bioeng., Nagaoka Univ.
Tech.)
インスリン受容体全長構造モデリングとその分子動力学研究
Computational modeling of full-length insulin receptor and its molecular dynamics
Yoshiharu Mori (Grad. Sch. of Sys. Info., Kobe Univ.)– S53 –

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Size evolution of antibody aggregates by the adsorption of serum albumin
Tomohito Nakayama1,2, Muneaki Hase1, Atsushi Hirano2 (1Grad. Sch. Sci. Tech., Univ. Tsukuba, 2NMRI,AIST)Theoretical Study on the Transport Cycle of the Heme ABC Transporter BhuUV-T
Koichi Tamura1, Yuji Sugita1,2,3 (1RIKEN R-CCS, 2RIKEN BDR, 3RIKEN CPR)
ヤエヤマサソリ由来殺虫性毒素 LaIT2 の C 末端ドメインの大腸菌大量発現系構築
Constructon of the E.coli ovrexpression system for the C-terminal domain of LaIT2, an insecticidal
toxin from Liocheles australasiae
Chiharu Tatsushiro1, Maiki Tamura2, Shinya Ohki2, Hayato Morita1,3 (1Grad.Sch.Sci.,Josai Univ,
2Grad.Sch.Mat Sci.,JAIST, 3Fas Sci.,Josai Univ)
高密度マイクロウェルアレイによる酵素関連タンパク質のセレクションを目的とした、ペプチドリガーゼによる遺伝子型-表現型対応付け手法の開発
Peptide ligase display (PL display) for selection of enzyme-related protein by combination withhigh-density microwell array chip
Shingo Ueno1,2, Shusuke Sato1,2, Fumi Toshioka1, Shoichi Tsuchiya1, Takanori Ichiki1,2 (1iCONM,
Kawasaki Ins. Ind. Prom., 2Grad. Sch. Eng., Univ. Tokyo)
長時間タンパク質ダイナミクスの拡散マップによる解析
Diffusion map analysis of long time protein dynamics
Hiroshi Fujisaki1, Hiroto Kikuchi1, Hiromichi Suetani2, Ayori Mitsutake3 (1Nippon Medical School,
2Grad. Sch. Eng., Oita Univ., 3Grad. Sch. Sci., Meiji Univ.)
Molecular simulation of pH effect on emission color changes through hydrogen-bond networks infirefly luciferase and its mutants
Kota Nosaka1, Yuto Kudo2, Naohisa Wada1 (1Grad. Sch. Life Sci., Univ.Toyo, 2Fac. Food and Nu. Sci.,
Univ.Toyo)Spectroelectrochemical FTIR studies of an electron-bifurcating [FeFe] hydrogenase
Nipa Chongdar2, Krzysztof Pawlak2, Olaf Rudiger2, Edward Reijerse2, Patricia Rodriguez-Macia2,
Wolfgang Lubitz2, James Birrell2, Hideaki Ogata1,2 (1ILTS, Hokkaido Univ., 2MPI/CEC)
演題取り消しD313Y 変異をもつノーマル型べん毛繊維を用いた多型変換に関与するアミノ酸相互作用の推測
Prediction of amino acid interactions for polymorphic transformation with normal flagellar
filaments with the D313Y curly mutation
Ayano Yanagita1, Minami Oohata1, Hikaru Tsufuku1, Shigeru Yamaguchi1, Fumio Hayashi2,
Kenji Oosawa1 (1Dept. Chem. & Chem. Biol., Sch. Sci. Technol., Gunma Univ., 2Ctr. Instr. Anal. Gunma
Univ.)
統計力学モデルの拡張によるタンパク質のフォールディング経路の解析
Protein folding mechanisms predicted by an extended statistical mechanical model
Koji Ooka1, Munehito Arai1,2 (1Dept. Phys., Univ. Tokyo, 2Dept. Life Sci., Univ. Tokyo)
Structural Stability and Unfolding Kinetics of a lytic polysaccharide monooxygenase, CBP21
Yuichi Nakajima, Takeshi Watanabe, Kazushi Suzuki, Hayuki Sugimoto (Grad. Sch. Sci. & Tech., Niigata
Univ.)
Search for Partial Structural Space of Specific Loop Residues by Hydrogen Bond and StericRepulsion
Hiroto Murata, George Chikenji (Dept. Appl. Phys., Nagoya Univ.)
機械学習による単粒子 X 線回折像の改善
Improvement for Noisy X-ray Single-Particle Diffraction Pattern using Convolutional Neural
Network
Atsushi Tokuhisa1,2, Yoshinobu Akinaga1,3, Kei Terayama1,4, Yasushi Okuno1,5 (1RIKEN Medical
Sciences Innovation Hub Program (MIH), 2RIKEN Center for Computational Science (R-CCS), 3VINAS
Co.,Ltd., 4Computational Life Science, Yokohama City Univ., 5Graduate School of Medicine, Kyoto Univ.)– S54 –

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c-Myb-KIX 相互作用を阻害するヘリカルペプチドの合理的設計
Rational design of an α-helical peptide to inhibit c-Myb-KIX interaction
Shunji Suetaka1, Yoshiki Oka1, Tomoko Kunihara1, Yuuki Hayashi1, Munehito Arai1,2 (1Dept. Life Sci.,
Univ. Tokyo., 2Dept. Phys., Univ. Tokyo)
Optimized Go-MARTINI coarse-grained force field parameters based on structural flexibility of FBAR protein Pacsin1 on lipid membrane
Md. Iqbal Mahmood1, Adolfo Poma2, Kei-ichi Okazaki1 (1Institute for Molecular Science, 2Institute ofPhysics, Polish Academy of Sciences, Al. Lotnikow 32/46, 02-668 Warsaw, poland)
タンパク質脱イミノ化酵素 PAD3 の構造機能相関解明
Elucidation of the structure-function relationship of peptidyl arginine deiminase type 3
Mizuki Sawata1, Kazuma Funabashi1, Tetuya Ohwada1, Hidenari Takahara2,3, Masaki Unno1,3 (1Grad.
Sch. Sci. Eng., Univ. Ibaraki, 2Sch. Agr., Univ. Ibaraki, 3Frontier., Univ. Ibaraki)
トキソプラズマ症を引き起こす病原性原虫トキソプラズマの寄生胞膜破壊に関わる Irgb6 の結晶構造
Crystal structure of Irgb6, which is involved in the destruction of a membrane-boundparasitophorous vacuole of Toxoplasma gondii
Yumiko Saijo-Hamano1, Naoki Sakai2, Yoshiaki Sakihama1, Masahiro Yamamoto3, Ryo Nitta1 (1Grad.
Sch. Med., Kobe Univ., 2RIKEN, RCS, 3RIMD, Osaka Univ.)
糸状仮足観察のための Cryo-CLEM 法の検討
A study of the Cryo-CLEM method for the observation of filopodia
Miho Nakafukasako, Tomoya Higo, Yusuke V. Morimoto, Takuo Yasunaga (Grad. Sch. Comp. Sci. Syst.
Eng., KIT.)
ヘリオロドプシンおよびシゾロドプシンの構造から明らかになった微生物型ロドプシンの多様性
Structures of heliorhodopsin and schizorhodopsin elucidate the structural diversity of microbial
rhodopsins
Wataru Shihoya1, Keiichi Inoue2, Singh Manish3, Akimitsu Higuchi1, Masae Konno2, Rei Yoshizumi3,
Takayuki Uchihashi4, Hideki Kandori3, Osamu Nureki1 (1Dept. of Biol., Grad. Sch. Sci, Univ. of Tokyo,
2ISSP, Univ. of Tokyo, 3Life Sci. Appl. Chem., Grad. Sch. Eng., NIT, 4Dept. of Phys., Grad. Sch. Sci,
Nagoya Univ.)
The relationship between designability of protein and preference of local structures: A latticemodel study
Kazuma Toko, George Chikenji (Dept.Appl.Phys.,Nagoya Univ.)
β ストランドと α ヘリックスをつなぐループが特定の主鎖二面角およびアミノ酸を選択する理由
Why loops connecting a β-strand and an α-helix prefer particular dihedral angles and amino acids
Megumi Nakajima, George Chikenji (Dept.Appl.Phys.,Nagoya Univ.)
New insight into ion transport mechanism of the Na+/H+ antiporter PaNhaP revealed by transition
path shooting and Markov state model
Titouan Jaunet, Kei-ichi Okazaki (Institute of molecular science (IMS) okazaki, japan)
Molecular dynamics simulations of the H.pylori FliG N-terminus
Dagnija Tupina1,2, Alexander Krah2, Chrystala I. Constantinidou1, Peter J. Bond2 (1Univ. of Warwick,
2A*STAR BII)
A large-scale structural and evolutionary analysis of protein loop regions
Lin Zhang1, Hafumi Nishi1,2 (1Tohoku University, 2Ochanomizu University)
Ligand Docking Parallel Cascade Selection Molecular Dynamics (ld-PaCS-MD) の開発と応用
A Development of Ligand Docking Parallel Cascade Selection Molecular Dynamics (ld-PaCS MD)
and its applications
Hayato Aida1,2, Yasuteru Shigeta2, Ryuhei Harada2 (1Bio., Degree Programs in Life and Earth Sci., Univ.
of Tsukuba., 2CCS, Univ. of Tsukuba.)– S55 –

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アスパラギン酸スキャニングを用いた赤外分光法によるタンパク質内局所的環境変化のマッピン
グ解析
Mapping of the local environmental changes in proteins by FTIR spectroscopy with aspartic acidscanning
Masanori Hashimoto, Kota Katayama, Manish Singh, Yuji Furutani, Hideki Kandori (Grad. Sch. Eng.,
Nagoya Inst. Tech.)
Computational Study of Temperature-Dependent Protein Glass Transition under Varying Solvent
Compositions
Michelle Yaochai1,2, Emmanuella Li2, Joanna Ng2, Peter J. Bond2, Alexander Krah2 (1NUS High Sch.,
2Bioinformatics Inst., A*STAR)
計算モデリングを用いたアブラナ科植物の自家不和合性を制御するタンパク質 SRK/SP11 複合体の包括的理解Comprehensive understanding of SRK/SP11 protein complexes of Brassicaceae using
computational modeling
Yoshitaka Moriwaki1, Tohru Terada1, Koji Murase2, Seiji Takayama2, Kentaro Shimizu1 (1Dept. of
Biotechnol., Grad. Sch. of Agri. and Life Sci., Univ. of Tokyo, 2Appl. Biol. Chem., Grad. Sch. of Agri. andLife Sci., Univ. of Tokyo)
Effect of the divalent cation for the activity of alcohol dehydrogenase from Sulfolobus tokodaii
Shuichiro Goda1,2, Sho Takashima2, Kosei Kajiyama2, Yuka Nagano2, Takuro Uchida2, Hideaki Unno2,
Tomomitsu Hatakeyama2 (1Fuc. Sci. Eng., Soka Univ., 2Grad. Sch. Eng., Nagasaki Univ.)
細菌機械受容チャネル MscL の G46D 変異体を用いた張力感受活性化機構の考察に関するシミュ
レーション研究
Computational Study Focusing on the Mechano-Gating in the Bacterial Mechanosensitive
Channel MscL Using G46D GOF mutant
Yasuyuki Sawada1, Ken'ichi Hashimoto2, Hisashi Kawasaki2, Masahiro Sokabe3 (1Dept. Nutrition Nagoya
Univ. Economics Fac. Human Life Sci., 2Biotechnology Res Ctr, Univ Tokyo, 3Mechanobiology Lab.
Nagoya Univ. Grad. Sch. Med.)
LI-cadherin 遺伝子上の SNP に伴う大腸がん転移リスク上昇の分子メカニズム
Molecular basis of increased risk of colorectal cancer metastasis caused by SNPs in LI-cadherin
gene
Anna Yui1, Chika Kikuchi2, Shuichiro Goda3, Takahiro Maruno4, Susumu Uchiyama4, Makoto Nakakido1,
Daisuke Kuroda1,5, Satoru Nagatoishi6, Osamu Arai7, Hiroko Iwanari8, Takao Hamakubo9,
Kouhei Tsumoto1,2,6 (1Dept. of Bioeng., Sch. of Eng., Univ. of Tokyo, 2Dept. of Chem. Biotech., Sch. ofEng., Univ. of Tokyo, 3Grad. Sch. of Sci. Eng., Soka Univ., 4Dept. of Biotech., Grad. Sch. of Eng., Osaka
Univ., 5Med. Dev. Dev. Reg. Res. Center, Sch. of Eng., Univ. of Tokyo, 6Inst. of Med. Sci., Univ. of Tokyo,
7RCAST, Univ. of Tokyo, 8Inst. of Immunol. Co., Ltd., 9Nippon Med. Sch.)Aβ 産生抑制タンパク質 ILEI の活性中心の同定
Identification of the active center of the Aβ production suppressor protein ILEIEmi Hibino1,2, Masaki Nishimura2 (1Grad. Sch. Pharm. Sci., Nagoya Univ., 2Mol. Neuro., Shiga Univ.
Med. Sci.)
GTP-チューブリンはどのようにして微小管の核を生成するか? (1) 直線型オリゴマーの形成
How do GTP-tubulins nucleate microtubules? (1)Formation of straight oligomers
Rie Ayukawa1, Seigo Iwata1, Hiroshi Imai2,5, Shinji Kamimura2, Masahito Hayashi1, Kien Ngo1,
Itsushi Minoura1, Seiichi Uchimura1, Tsukasa Makino1, Hideki Shigematsu6, Ken Sekimoto3,
Benoit Gigant4, Etsuko Muto1 (1RIKEN CBS, 2Chuo Univ., 3Paris Univ., 4Paris-Saclay Univ., 5Osaka Univ.,
6RIKEN BDR)
GTP-チューブリンはどのようにして微小管の核を生成するか? (2) オリゴマーのラテラルな相互作用
How do GTP-tubulins nucleate microtubules? (2)Lateral association of oligomers
Seigo Iwata1, Rie Ayukawa1, Hiroshi Imai2,5, Shinji Kamimura2, Ken Sekimoto3, Benoit Gigant4,
Etsuko Muto1 (1CBS, RIKEN, 2Chuo Univ., 3Paris Univ., 4Paris-Saclay Univ., 5Osaka Univ.)– S56 –

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クライオ電子顕微鏡を用いたシトクロム酸化酵素とシトクロム c の複合体構造解析
The structural analysis of cytochrome c oxidase complexed with cytochrome c using cryo-electron
microscopy
Atsuhiro Shimada1, Daisuke Kozai2, Kouki Nishikawa3,4, Yoshinori Fujiyoshi3,4, Gyokucho Sho1,
Takumi Mizutani1, Kazutoshi Tani5 (1Dept. Appl. Life Sci., Fac. Appl. Biol. Sci., Gifu Univ., 2Cell. Struct.
Phys. Inst., Nagoya Univ., 3Adv. Res. Inst., Tokyo Med. Dent. Univ., 4CeSPIA Inc., 5Grad. Sch. Med., Mie
Univ.)
重み付きアンサンブル法による Pin1 異性化のパスサンプリング
Obtaining path ensemble of Pin1-catalyzed cis-trans isomerization by weighted ensemble
simulation
Kei Moritsugu1, Norifumi Yamamoto2, Yasushige Yonezawa3, Shin-ichi Tate4, Hiroshi Fujisaki5(1Yokohama City Univ., 2Chiba Tech., 3Kindai Univ., 4Hiroshima Univ., 5Nippon Med. Sch.)
水素結合経由の J 値の定量的解析
Quantitative analysis of J value via hydrogen bonds
Hiroki Nakajima1, Taiki Koizumi1, Masaki Uuno2, Masaki Mishima1 (1Grad.Sch.Sci.,
Univ,TokyoMetropolitan, 2Grad.Sch.Sci,. Univ,Ibaraki)
Design of cyclic and linear peptides interacting with transition metal ions
Rikako Morishita, Atsuo Tamura (Grad. Sch. Sci., Kobe Univ.)
細胞壁を持たない細菌のチューブリンの解析
Analysis of bacterial tubulin in cell wall-less bacterium
Taishi Kasai1, Yuhei Tahara2, Makoto Miyata2, Daisuke Shiomi1 (1Col. Sci., Rikkyo Univ., 2Grad. sch. Sci.,
Osaka City Univ.)
コレステロールが膜貫通ペプチドの二量体化に与える影響に関する分子動力学的解析
Effect of cholesterol on the dimerization of transmembrane peptides analyzed by the molecular
dynamics simulations
Hayato Itaya1, Kota Kasahara2, Yoshiaki Yano3, Katsumi Matsuzaki3, Takuya Takahashi2 (1Grad. Sch.
Life Sci., Ritsumeikan Univ., 2Coll. Life Sci., Ritsumeikan Univ., 3Grad. Sch. Pharm. Sci., Kyoto Univ.)
残基間平均距離統計に基づく方法によるフラボヘモグロビンのフォールディング機構予測
Prediction of folding mechanism of flavohemoglobins using techniques based on inter -residue
average residue distance statistics
Maho Osugi, Takeshi Kikuchi (Dept. Bioinf. Col. Biosci. Ritsumeikan Univ.)
ドッキングシミュレーションによる Cyclin-dependent kinase-like 5 の基質タンパク質の同定
Identification of Cyclin-dependent kinase-like 5 substrate protein using docking simulation
technique
Aya Takahara1, Shoichi Katayama2, Takako Kawano2, Tetsuya Inazu2, Takeshi Kikuchi1 (1Dept. Bioinf.
Col. Biosci. Ritsumeikan Univ., 2Col. Pharm.Sci. Ritsumeikan Univ.)
構造研究のためのタンパク質連結法の開発
Development of protein ligation techniques for structural studies
Takumi Suzuki (Grad. Sch. Sci., Univ. TMU)
ネガティブ染色電子顕微鏡法により明らかにされた繊毛ダイニンの新規構造
Novel isolated ciliary dynein structure revealed by negative stain EM
Yici Lei1, Hiroshi Imai1, Akira Fukunaga1, Shinji Kamimura2 (1Dep. Biol. Sci., Grad. Sch. Of Sci., Osaka
Univ., 2Dept. Biol. Sci., Chuo Univ., 3Dept. Life Sci., Prefect. Univ. Hiroshima)
カメレオンモデルの二面角ポテンシャルの改良による NtrC の構造転移の解明
Conformational transition of NtrC elucidated by the improvement of dihedral angle potential inchameleon model
Taisei Nagata, Masaki Sasai, Tomoki P. Terada (Dept. Appl. Phys., Grad. Sch. Eng., Nagoya Univ.)– S57 –

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Expression and Purification of Intact Small Peptides through a Novel Calmodulin-Fusion Protein
System
Hao Gu1, Koki Onuma1, Takasumi Kato1, Hiroaki Ishida2, Yasuhiro Kumaki1, Takashi Tsukamoto1,3,
Takashi Kikukawa1,3, Makoto Demura1,3, Hans J. Vogel2, Tomoyasu Aizawa1,3 (1Grad. Sci. Life Sci.,
Hokkaido univ., 2Dep. of Biol. Sci., Univ. of Calgary, 3GI-CoRE, Hokkaido univ.)
RNA 結合タンパク質 FUS の液液相分離を制御するペプチドの探索
Search for peptides to control liquid-liquid phase separation of RNA binding protein FUS
Rika Chiba1,2, Nanako Iwaki1,3, Saori Kanbayashi1, Keisuke Ikeda4, Tomoshi Kameda5,
Kiyoto Kamagata1,2,3 (1IMRAM, Tohoku Univ., 2Grad. Sch. Life Sci., Tohoku Univ., 3Dep. Chem., Grad.
Sch. Sci., Tohoku Univ., 4Sch. Pharm. Pharm. Sci., Univ. Toyama, 5AIRC, AIST)
天然変性タンパク質 LAF-1RGG ドメインの一分子蛍光分光測定による構造特性評価
Conformational properties of the intrinsically-disordered RGG domain of LAF-1 detected bysingle-molecule fluorescence spectroscopy
Michiko Kimura1,2, Saya Nakano1,2, Hiroto Takahashi1, Hiroyuki Oikawa1, Satoshi Takahashi1 (1IMRAM,
Tohoku Univ., 2Grad. Sch. Life Sci., Tohoku Univ.)
Cryo-EM revealed unique and diverse binding schemes of the microtubule inner proteins at the
inner junction region of cilia
Muneyoshi Ichikawa1, Ahmad Khalifa2, Daniel Dai2, Shintaroh Kubo3, Corbin Black2, Katya Peri2,
Thomas McAlear2, Simon Veyron2, Shun-Kai Yang2, Javier Vargas2, Susanne Bechstedt2,
Jean-Francois Trempe2, Khanh-Huy Bui2 (1NAIST, 2McGill University, 3Kyoto University)
生きた細胞における DXT 法を用いた nAChR のリガンド依存的な分子内部運動の計測
Ligand-dependent intramolecular motion of nAChR in living cells detected by DXT
Koichiro Oishi1, Yuri Nishino1, Hiroshi Sekiguchi2, Yasuhiro Kashino1, Yuji C. Sasaki3, Atsuo Miyazawa1(1Grad. Sch. Sci., Univ. Hyogo, 2JASRI, 3Grad. Sch. Sci., The Univ Tokyo)
Characterization of properties of microtubule inner protein FAP85
Yoshitoki Shibao1, Corbin Black2, Muneyoshi Ichikawa1, Junya Kirima4, Kazuhiro Oiwa3,
Khanh-Huy Bui2, Tomoya Tsukazaki1 (1NAIST, 2McGill University, 3NICT, 4University of Hyogo)
Binding mode analysis of Hepatitis B virus X protein to DDB1 with Fluorescent based technology
detecting Protein-Protein Interactions
Katsumi Omagari (Department of Virology, Nagoya City University Graduate School of Medical
Sciences)
大腸菌フェリチン変異体の荷電状態に関する研究
A study on the charge states of Escherichia coli ferritin mutants
Takumi Kuwata, Daisuke Sato, Kazuo Fujiwara, Masamichi Ikeguchi (Dept. of Biosci., Soka Univ)
クライオ電子顕微鏡によるヒト PAC1 受容体の構造解析
Cryo-EM structure of the human PAC1 receptor coupled to an engineered heterotrimeric G protein
Kazuhiro Kobayashi1, Wataru Shihoya1, Tomohiro Nishizawa1, Marie Ngako Kadji Francois2,
Junken Aoki2, Asuka Inoue2, Osamu Nureki1 (1Grad. Sch. Sci., Univ. Tokyo, 2Grad. Sch. Pharm. Sci., Univ.
Tohoku)Cryo-EM structure of Thermus thermophilus V/A-ATPase during the rotary catalysis
Atsuko Nakanishi1,3, Jun-ichi Kishikawa2,3, Kaoru Mitsuoka1, Ken Yokoyama3 (1Res. Ctr. for UHVEM,
Osaka Univ., 2Inst. for Protein Res., Osaka Univ., 3Faculty of Life Sci., Kyoto Sangyo Univ.)
タンパク質における連続する 3 つの残基で構成されるユニットの運動学的特性の解析
Analysis of the Kinematic Properties of Units Comprising Three Consecutive Residues in Proteins
Keisuke Arikawa (Fcl. Eng., Kanagawa Inst. of Tech.)
Reconistitution of Cecytb-2 in Phospholipid Bilayer Nanodisc and Meaurments of its Ferric
Reductase Activity
Hamed A. Abosharaf1,2, Yuki Sakamoto1, Mohammed El behery1, Thoria Diab2, Tarek M. Mohamed2,
Tetsunari Kimura1, Motonari Tsubaki1 (1Grad. Sch. Sci., Kobe Univ., 2Fac. Sci., Tanta Univ.)– S58 –

20081A

20082A*

20083A

20084A

20085A

20086A

20087A*

20088A

20089A

20090A

20091A

20092A

20093A

クライオ電子回折法による生体分子微小結晶の高分解能構造解析
High-resolution Structure Determination of Biomolecular Microcrystals by Cryo-Electron
Diffraction
Kiyofumi Takaba, Koji Yonekura, Saori Maki-Yonekua (SPring-8, RIKEN)
液―液相分離によって形成される多相液滴の作成
Multiphase droplet formed by liquid-liquid phase separation
Kanji Tomohara, Yoshihiro Minagawa, Hiroyuki Noji (Dept. Appl. Chem., Grad. Sch. Eng., Univ. Tokyo)
データベースアノテーションに基づく液滴の分析
Analysis of liquid droplets based on database annotations
Mitsuteru Iwatsuka1, Motonori Ota1, Satoshi Fukuchi2, Hiroto Anbo2 (1Nagoya university, 2Maebashi
Institute of Technology university)
免疫阻害機能の異なるリッサウイルス P 蛋白質 C 末端ドメインの構造比較
Structural comparison of the C-terminal domain of functionally divergent lyssavirus P proteins
Aoi Sugiyama1, Tomo Nomai1, Xinxin Jiang1, Miku Minami1, Min Yao1, Katsumi Maenaka1, Naoto Ito2,
Paul Gooley3, Gregory Moseley4, Toyoyuki Ose1,5 (1Faculty of Advanced Life Sci., Hokkaido Univ.,
2Faculty of Appl. Biol. Sci., Gifu Univ., 3School of Bio21 Mol. Sci. and Biotechnol., Univ. of Melbourne,
4School of Biomed. Sci., Monash Univ., 5PRESTO, Japan Science and Technology Agency)
High resolution X-ray analysis reveals a stable structure around the catalytic amino acid Asp52
in lysozyme-sugar complex
Ichiro Tanaka1,2, Ryota Nishinomiya1 (1Grad. Sch. Sci. & Eng., Ibaraki Univ., 2Frontier Ctr, Ibaraki
Univ.)
シトクロム c が仲介する多段階電子伝達反応における呼吸鎖超複合体形成の機能的意義
Functional significance of formation of respiratory supercomplex for multiple electron transfer
reaction mediated by cytochrome c
Wataru Sato, Peter Brzezinski (Stockholm Univ. Fac. of Nat. Sci.)
PaCS-MD/MSM を用いたタンパク質複合体の速度定数評価
Kinetic rate evaluation for protein complexes by PaCS-MD/MSM
Yoshiki Miyazawa, Phouc Duy Tran, Kazuhiro Takemura, Akio Kitao (Grad. Sch. Life Sci Tech., TokyoTech)
How internal cavities destabilize a protein
Ryo Kitahara1, Mengjun Xue2, Takuro Wakamoto3, Frans A.A. Mulder4 (1Pharm. Sci., Ritsumeikan Univ.,
2Dep. Chem. Univ. Washington, 3Grad. Sch. Life Sci., Ritsumeikan Univ., 4iNANO, Univ. Aarhus)
クライオ電子線トモグラフィー法からの糸状仮足中のアクチン繊維とファシンのサブトモグラム
平均化
Subtomogram Averaging of F-Actin with Fascin in Filopodia by Cryo-Electron Tomography
Atsuko Nakanishi1, Naoko Kajimura1, Shun Kurita2, Takuo Yasunaga3, Kaoru Mitsuoka1 (1Res. Ctr.
UVHEM, Osaka Univ., 2Grad. Sch. Eng., Osaka Univ., 3Grad. Sch. Comp. Sci. Syst. Eng., KIT)
Could the biogenic zinc oxide nanoparticles inhibit the ATPase activity of ABC transporters?
Aliaa M. Radwan1,2, Mai M. El-Keiy2, Tarek M. Mohamed2, Tetsunari Kimura1 (1Grad. Sch. Sci., Kobe
Univ., 2Fac. Sci., Tanta Univ.)
Cold adaptation and high thermal stability mechanism of glucokinase from psychrophilic bacteria
are revealed by spin-labeling ESR
Akane Yato (Grad. Sch. Adv Hea Sci., Univ. Saga)
エネルギー準位統計とペプチドの分子進化
Energy level statistics and molecular evolution of peptide
Masanori Yamanaka (CST, Nihon Univ.)
ドーパミン制御タンパク質 MAO-B のミトコンドリア膜中でのダイナミクス
The dynamics of dopamine-regulated protein MAO-B in the mitochondrial membrane
Masaki Ottawa1, Lisa Matsukura1, Naoyuki Miyashita1, Ryuichi Harada2, Yuichi Kimura1,
Shozo Furumoto3 (1BOST, KINDAI Univ., 2Med. Tohoku Univ., 3CYRIC, Tohoku Univ.)– S59 –

20094A*

20095A
20096A
20097A

20098A

20099A

20100A*

20101A

20102A*

20103A

20104A

20105A

20106A

20107A

20108A

20109A

Engineering of genome editing protein Cas9 that slides along DNA faster and might enableefficient target search
Trishit Banerjee1,2, Dwiky Rendra Graha Subekti1,2, Hiroto Takahashi1, Satoshi Takahashi1,
Kiyoto Kamagata1 (1IMRAM, Tohoku University, 2Grad. Sch. Sci., Tohoku University)
Influence of disulfide-closed loop structures on the stability of alpha-helix
Yuki Yanagida, Masamichi Ikeguchi, Kiyomi Yoshida, Kazuo Fujiwara (Dept.of Biosci., Soka Univ.)
CNT aptamers selection and strucuture study
Ting-Chieh Chu, Huanwen Han, Ichiro Yamashita (Graduate School of Engineering, Osaka University)
逆並行 β-シート中の隣接ストランド間の Cα 距離の解析
Analysis of Cα distances between adjacent strands in anti-parallel β-sheets
Hiromi Suzuki (Sch. Agri., Meiji Univ.)
A method for producing recombinant cryptdin by enhancing inclusion body formation
Yuchi Song1, Weiming Geng1, Shaonan Yan1, Wendian Yang1, Yi Wang1, Tomoyasu Aizawa1,2 (1Grad.
Sch. of Life Sci, Hokkaido Univ., 2GI-CoRE, Hokkaido Univ.)
クライオ電顕データを用いた MD 力場の評価
Assessment of force-field accuracy using data of cryogenic electron microscopy
Tomotaka Oroguchi1,2, Mao Oide1,2, Taiki Wakabayashi1,2, Masayoshi Nakasako1,2 (1Faclt. Sci. Tech.,
Keio Univ., 2RIKEN SPring-8 Center)
TAT ロドプシン変異体に対する陽イオン結合の分光学的研究
Spectroscopic study of cation binding to a TAT rhodopsin mutant
Teppei Sugimoto, Kota Katayama, Hideki Kandori (Nagoya institute of technology)
Structural changes of a-synuclein along the lipid-binding and oligomerization revealed byfluorescence lifetime measurements
Ko Sasada, Ryosuke Matsubara, Koichi Fujii, Tetsunari Kimura (Kobe Univ., Grad. Sch. of Sci.)
単細胞緑藻由来の葉緑体 ATP 合成酵素完全複合体のワンステップ単離と制御機構の解析
One-step purification and functional analysis of the chloroplast ATP synthase complex
Kentaro Akiyama1,2, Ken-ichi Wakabayashi1,2, Toru Hisabori1,2 (1Grad. Sch. Life Science and Technology,
Titech, 2CLS, Titech)
フォトンファクトリーにおける生体高分子の X 線溶液散乱
Current Status of BioSAXS at the Photon Factory
Nobutaka Shimizu, Kento Yonezawa, Masatsuyo Takahashi, Keiko Yatabe, Yasuko Nagatani (KEK,
IMSS, PF)
緩和モード解析を用いた NTL9 のシミュレーションデータの解析
Analysis of simulations of NTL9 using relaxation mode analysis
Ayori Mitsutake (Dept. of Physics, Meiji Univ.)
Theoretical Studies of Association-Dissociation of Plastocyanin by Coarse Grain Simulation
Dian Fitrasari, M.S. Arwansyah, Helmia Jayyinunnisya, Kazutomo Kawaguchi,
Hidemi Nagao (Kanazawa University)
生体分子構造における形状と機能の関係
Shape similarity and functional similarity in biomolecular structures
Hirofumi Suzuki1, Takeshi Kawabata2, Kei Yura1, Genji Kurisu2 (1Waseda Univ., 2IPR, Osaka-univ.)
Pressure-induced acceleration of the cyanobacterial circadian clock
Keita Mitsuhashi1, Rina Sakurai2, Soichiro Kitazawa2, Kazuki Terauchi1, Ryo Kitahara2 (1Grad. Sch. Life
Sci., Univ. Ritsumeikan, 2Depart. Pharm., Univ. Ritsumeikan)
In-cell NMR analysis of an anticancer candidate compound against a chemokine-signaling protein
FROUNT
Sosuke Yoshinaga1, Takafumi Sato1, Airi Higashi1, Mitsuhiro Takeda1, Yuya Terashima2,3,
Etsuko Toda2,3,4, Kouji Matsushima2,3, Hiroaki Terasawa1 (1Fac. Life Sci., Kumamoto Univ., 2Grad. Sch.
Med., Univ. Tokyo, 3RIBS, Tokyo Univ. Sci., 4Nippon Med. Sch.)
Intrinsically Disordered Protein Studied by Multi-scale Divide-and-conquer Molecular Dynamics
Simulation
Hiromitsu Shimoyama1, Yasushige Yonezawa2 (1Kitasato Univ., 2Kindai Univ.)– S60 –

20110A*

20111A

20112A*

20113A

20114A

20115A*

20116A

20117A

20118A

20119A*

20120A

Saframycin A 生合成関連蛋白質のクライオ電子顕微鏡単粒子解析
Cryo-EM study on saframycin A biosynthesis related protein
Kiichi Honda1, Takashi Matsui2, Ryoko Komatsu3, Ryo Tanifuji4, Hiroki Oguri4, Takeshi Yokoyama1,
Yoshikazu Tanaka1 (1Laboratory of Applied Biological Molecular Science, Graduate School of Life
Sciences, Tohoku University, 2Laboratory of Biophysics, Department of Physics, School of Science,
Kitasato University, 3Department of Applied Chemistry, Graduate School of Engineering, Tokyo Universityof Agriculture, 4Department of Chemistry School of Science The University of Tokyo)
A Singularity-Free Torsion Angle Potential for Coarse- Grained Molecular Dynamics Simulations
Cheng Tan1, Jaewoon Jung1,2, Chigusa Kobayashi1, Yuji Sugita1,2,3 (1RIKEN Center for Computational
Science, 2RIKEN Cluster for Pioneering Research, 3RIKEN Center for Biosystems Dynamics Research)
クライオ電子顕微鏡単粒子解析による百日咳壊死毒の構造解析
Cryo-electron microscopy single particle analysis of pertussis dermonecrotic toxin
Atsushi Tsugita1, Takashi Matsui2, Yasuhiko Horiguchi3, Takeshi Yokoyama1, Yoshikazu Tanaka1(1Laboratory of Applied Biological Molecular Science, Graduate School of Life Sciences, Tohoku
University, 2Laboratory of Biophysics, Department of Physics, School of Science, Kitasato University,
3Department of Molecular Bacteriology, Research Institute for Microbial Diseases, Osaka University.)
Biflavonoids that inhibit ATPase and microtubule-gliding activities of mitotic kinesin Eg5
Tomisin H. Ogunwa1, Sadakane Kei1, Maruta Shinsaku1, Miyanishi Takayuki2 (1Department of
Bioinformatics, Graduate School of Engineering, Soka University, Hachioji, Japan, 2Graduate School ofFisheries and Environmental Sciences, Nagasaki University, Nagasaki, Japan)
分子動力学シミュレーションを用いた CDR-Grafting による合成 VHH における分子挙動の解析
Molecular dynamics analysis of structural effects of Grafting CDRs in synthetic VHHs
Seisho Kinoshita1, Makoto Nakakido1,2, Daisuke Kuroda1,2, Jose M.M. Caaveiro3, Kouhei Tsumoto1,2,4(1Dept. of Bioeng., Sch. of Eng., Univ. of Tokyo, 2Dept. of Chem. Biotech., Sch. of Eng., Univ. of Tokyo,
3Grad. Sch. of Pharm. Sci., Kyushu Univ., 4Inst. of Med. Sci., Univ. of Tokyo)
転写コアクチベータ CBP の KIX ドメインと転写因子の相互作用を標的としたペプチド阻害剤の合理的設計
Rational design of the peptide inhibitor targeting the interaction of the KIX domain of CBP withtranscriptional activators
Nao Sato1, Shunji Suetaka1, Yuuki Hayashi1, Munehito Arai1,2 (1Dept. Life Sci., Univ. Tokyo, 2Dept. Phys.,Univ. Tokyo)
分布推定アルゴリズムと勾配降下法最適化アルゴリズムによる単粒子解析初期モデル生成
Initial model generation in single particle analysis using Estimation of Distribution Algorithms andgradient descent optimization
Nobuya Mamizu1,2, Takuo Yasunaga1 (1Grad. Sch. Comp. Sci., Kyushu Inst. Tech., 2SYSTEM INFRONTIER INC.)
粗視化ペプチドの安定構造探索に向けたアミノ酸間相互作用ポテンシャルの開発
Amino-Acid Pair Interaction Potentials for Coarse Grained Peptide Folding
Chieko Terashima, Yoshiaki Tanida, Hiroyuki Sato (Fujitsu Laboratories Ltd.)
環状ペプチド中の隣接プロリンに特徴的な異性化
Characteristic isomerization of two adjacent prolines in a cyclic peptide
Yoshiaki Tanida, Chieko Terashima, Hiroyuki Sato (Fujitsu Labs.)
マイコプラズマ・モービレのモーター構成タンパク質 MMOB1620 の SAXS による構造解析
Structural Analysis of MMOB1620, Component Protein of Mycoplasma mobile’s Motor, by SAXS
Hiroki Sato1, Hisashi Kudo2,3, Yuuki Hayashi3, Syunji Suetaka3, Koji Ooka4, Munehito Arai3,4,
Makoto Miyata1,5 (1Grad. Sch. Sci., Osaka City Univ., 2Bioengineering center, Kobe Univ., 3Dept. Life Sci.,
Univ. Tokyo., 4Dept. Phys., Univ. Tokyo., 5OCARINA, Osaka City Univ.)
Multiscale Modeling Approach for Conformational Search of Macrocyclic Peptides
Hiroyuki Sato, Chieko Terashima, Yoshiaki Tanida (Fujitsu Laboratories Ltd.)– S61 –

20121A

20122A

20123A*

20124A

20125A

20126A

20127A

20128A

20129A*

20130A

20131A*

20132A*

20133A*

非リボソーム分子機械によるペプチド合成の静電的ラチェット機構
Electrostatic ratcheting mechanism of peptide synthesis by non-ribosomal molecular machine
Jun Ohnuki, Mitsunori Takano (Dept. of Pure & Appl. Phys., Waseda Univ.)
Local Structural Similarity of Mononucleotide Binding Sites Around Different Chemical Groups in
Ligands
Shota Kawakami1, Hafumi Nishi2,3, Kengo Kinoshita1,2 (1Grad. Sch. Life Sci., Tohoku Univ., 2Grad. Sch.
Info. Sci., Tohoku Univ., 3Fac. Core. Res., Ochanomizu Univ.)
Secondary structure transformation of artificially designed peptide nanofibers
Minami Kurokawa1, Mika Hirose2, Akihiro Kawamoto2, Atsuo Tamura1 (1Grad. Sch. Sci., Univ. Kobe.,
2IPR,Univ. Osaka.)
分子クラウディング環境における光活性化アデニル酸シクラーゼの光反応
Crowding effect on reaction dynamics of photoactivated adenylate cyclase
Hiroto Murakami, Masahide Terazima, Yusuke Nakasone (Grad. Sch. Sci., Univ. Kyoto)
電子伝達系における複数のタンパク質複合体の複合体形成と構造安定性に関する理論的研究
Theoretical study on complex formation and conformational stability of multiple protein complexes
in electron transport system
Rena Saito, Kazutomo Kawaguchi, Hidemi Nagao (Grad. Comput. bio., Univ. Kanazawa)
高速原子間力顕微鏡を用いたアミロイド β 線維の伸長および抗アミロイド β 抗体による 線維伸長阻害の観察
HS-AFM observation of Amyloid β elongation and inhibition by antibodies
Shogo Miyajima1, Maho Yagi-Utsumi2, Takayuki Uchihashi1,2, Koichi Kato2 (1Dept of Phys, Nagoya univ,
2EXCELLS)
Bayesian inference and Iterative Boltzmann approach to coarse-grained local potential ofdisordered proteins
Azuki Mizutani, Shoji Takada, Giovanni B Brandani (Grad. Sch. Sci, Univ. Kyoto)
NMR Studies on Cup s 7, an Novel Allergen from Cypress Pollen
Jingkang Zheng1, Tomona Iizuka1, Xiaoshaung Lu1, Tomoyasu Aizawa1,2 (1Grad. Sci. Life Sci., Hokkaido
univ., 2GI-CoRE Hokkaido univ.)
アミノ酸溶媒中における芳香族アミノ酸の溶解度
Solubility of aromatic amino acids in amino acid solutions
Akira Nomoto, Suguru Nishinami, Kentaro Shiraki (Pure and Appl. Sci, Univ. Tsukuba)
経験ベイズ推定を用いた水の効果の最適化によるタンパク質デザイン
Protein design by optimization of role of water using empirical Bayes' estimation
Tomoei Takahashi1, George Chikenji2, Kei Tokita1 (1Grad. Sch. Inform. , Nagoya Univ., 2Grad. Sch.
Eng. , Nagoya Univ.)
脱水に応答して繊維構造を可逆的に形成するクマムシ固有の天然変性タンパク質の解析
Reversible fiber formation of tardigrade-unique intrinsically disordered proteins upon dehydrationstressAkihiro Tanaka, Tomomi Nakano, Takekazu Kunieda (Dept. of Biol. Sci., Grad. Sch. of Sci., Univ. ofTokyo)
スピロプラズマのらせん反転機構
Helical reversal machinery of Spiroplasma
Yuya Sasajima1, Takayuki Kato2, Tomoko Miyata3, Keiichi Namba3,4,5, Makoto Miyata1,6 (1Grad. Sch.
Sci., Osaka City Univ., Japan, 2IPR., Osaka Univ., Japan, 3Grad. Sch. Front. Biosci., Osaka Univ., Japan,
4BDR & SPring-8 Center, Riken, Japan, 5JEOL Yokogushi Res. Alliance. Lab. Osaka Univ., Japan,
6OCARINA, Osaka City Univ., Japan)
多重平衡状態を持つ光スイッチング蛍光タンパク質「Kohinoor2.0」の開発と、細胞内小器官動態の超解像イメージングへの応用
Photoswitchable fluorescent protein with multiple equilibria states enables super-resolution
imaging of intracellular dynamics
Ryohei Noma1, Tethuichi Wazawa1, Syusaku Uto2, Kazunori Sugiura1, Takeharu Nagai1 (1Nagai
laboratory, 2no affiliation)– S62 –

20134A

シアノバクテリア由来光受容タンパク質 GAF ドメインの立体構造解析
Structural study of a GAF domain of photosensor protein from Cyanobacteria
Taiki Koizumi1, Takahiro Aizu1, Takayuki Nagae3, Yuu Hirose2, Masaki Mishima1 (1Grad. Sch Sci, Tokyo
Metropolitan University, 2Department of Environmental and Life Sciences, Toyohashi University ofTechnology, 3Grad. Sch Eng, Univ.Nagoya)B. ヘム蛋白質・膜蛋白質・核酸結合蛋白質／B. Heme-, Membrane- & nucleic acid binding-protein
20135B

20136B

20137B

20138B*

20139B

20140B*

20141B*

20142B

20143B

20144B

ウシミトコンドリア呼吸鎖酸素還元酵素の 1.3Å 分解能構造が示唆する二量体化機構
The 1.3 Å resolution structure of bovine mitochondrial respiratory oxygen reductase suggests a
dimerization mechanism
Kyoko Shinzawa-Itoh1, Miki Hatanaka1, Kazuya Fujita2, Naomine Yano1, Yumi Ogasawara1, Jun Iwata2,
Eiki Yamashita3, Tomitake Tsukihara2,3, Shinya Yoshikawa2, Kazumasa Muramoto1 (1Grad. Sch. Life
Sci., Univ. Hyogo, 2Sch. Sci., Univ. Hyogo, 3IPR, Osaka Univ.)
ゲノム編集酵素の開発に向けたエングレイルドホメオドメインアレイの構造解析
Structural basis for an array of engrailed homeodomains toward the development of genomeediting enzymes
Tomoko Sunami, Yu Hirano, Taro Tamada, Hidetoshi Kono (iQLS, QST)
ナノディスクに再構成されたイネキシン 6 ギャップ結合ヘミチャネルの構造
Structures of the Innexin-6 gap junction hemichannels in nanodiscs
Batuujin Burendei1, Ruriko Shinozaki2, Masakatsu Watanabe3, Tohru Terada4, Kazutoshi Tani5,
Yoshinori Fujiyoshi6,7, Atsunori Oshima2,8 (1Sch. Sci., Nagoya Univ., 2Grad. Sch. Pharm. Sci., Nagoya
Univ., 3Grad. Sch. Frontier Biosci., Osaka Univ., 4III/GSII, Univ. Tokyo, 5Grad. Sch. Med., Mie Univ.,
6Adv. Res., TMDU, 7CeSPIA, Inc., 8CeSPI, Nagoya Univ.)
分子動力学シミュレーションを用いた、オレキシン 2 受容体の動的性質の研究
Dynamics of Orexin 2 Receptor Using Molecular Dynamics Simulations
Shun Yokoi, Ayori Mitsutake (Meiji University)
酵母の DNA 複製開始機構の一分子観察に向けて
Toward single-molecule observation of yeast pre-replicative complex assembly and firing
Mayu Terakawa S., Tsuyoshi Terakawa (Dep. Biophys, Grad. Sch. Sci., Kyoto Univ.)
β 切断酵素と APP の生体膜中での相互作用と α 切断酵素の構造予測
Interaction Between beta-Secretase and APP in The Biological Membrane, and The Structure
Prediction of The TM domain of alpha-Secretase
Kaori Yanagino, Naoyuki Miyashita (Grad. Sch. BOST, KINDAI Univ.)
マラリア原虫のトランスロコンである EXP2 ナノポアのチャネル電流計測
Channel current measurement of EXP2 nanopore as a translocon of the malaria parasite
Mitsuki Miyagi, Sotaro Takiguchi, Kazuaki Hakamada, Masafumi Yoda, Ryuji Kawano (Department of
Biotechnology and Life Science, Tokyo University of Agriculture and Technology)
四量体と二量体のへモグロビン平衡混合物の構造の柔らかさの違いによる分離
Separation of tetramer-dimer mixtures mutant hemoglobin by structural flexibility
Shigenori Nagatomo1, Kitagawa Teizo2, Nagai Masako3 (1Dept. Chem., Univ. Tsukuba, 2Grad. Sch.Life
Sci., Univ. Hyogo, 3Res. Center Micro-Nano Tech., Hosei Univ.)
Assembly of a trimeric autotransporter transmembrane domain assisted by BamA embedded into
the nanodisc
Eriko Aoki, Kazuo Fujiwara, Masamichi Ikeguchi (Dept. of Biosci., Soka Univ.)
ナノディスク再構成型ヘム ABC トランスポーターを用いた基質輸送機構の分光学的解析
Spectroscopic analysis of allocrite transport mechanism using nanodisc-reconstituted heme ABCtransporter
Takuya Asada1, Motonari Tsubaki1, Yoshitsugu Shiro2, Hiroshi Sugimoto3, Tetsunari Kimura1,4 (1Grad.
Sch. Sci., Kobe Univ., 2Grad. Sch. Life Sci. Univ. of Hyogo, 3RIKEN SPring-8, 4K-CONNEX)– S63 –

20145B

20146B*

20147B

20148B

20149B

20150B

20151B

20152B

20153B

20154B

20155B

膜環境の違いがアルカン水酸化酵素の活性に与える影響について
An effect of membrane environment for the activity of alkane hydroxylase
Takaki Okamoto1, Tomomi Kikuchi2, Shingo Nagano1, Tomoya Hino1 (1Grad. Sch. Eng., Tottori Univ.,
2Grad. Sch. Sus. Sci., Tottori Univ.)
Investigating the dissociation process of DBD-p53/DNA complex by PaCS-MD and MSM
Mohamed Marzouk Sobeh1,2, Akio Kitao1 (1School of Life Science and Technology, Tokyo Institute ofTechnology, 2-12-1, Ookayama, Meguro-ku, Tokyo, 152-8550, Japan, 2Physics Department, Faculty of
Science, Ain Shams University, 11566, Cairo, Egypt)
Electrochemical studies of human neuroglobin and cytoglobin using nanostructured electrode
Yasuhiro Mie1, Kyoka Takahashi1, Itoga Yuka2, Kenta Sueyoshi2, Ryo Torii2, Jingkai Shen2,
Takumi Tanaka2, Hirofumi Tsujino2, Taku Yamashita3 (1Bioproduction Res. Inst., AIST, 2Grad. Sch.
Pharm. Sci., Osaka Univ., 3Sch. Pharm., Mukogawa Women’s Univ.)
スピンラベル ESR 分光法による HP1 の天然変性領域の動的構造解析： DNA 結合とリン酸化の影響
Structural dynamics of IDP region in heterochromatin protein HP1 by spin-labeling ESR: Effects
of DNA binding and phosphorylation
Toshiaki Arata1,5, Kazunobu Sato4, Ena Hirai4, Yuichi Mishima5, Takeji Takui4, Toru Kawakami5,
Hironobu Hojo5, Risa Mutoh6, Toshimichi Fujiwara5, Makoto Miyata1, Isao Suetake2,3,5 (1Dept. Biol., Grad.
Sch. Sci., Osaka City Univ., 2Nakamura Gakuen Univ., 3Twin Research Center, Osaka Univ., 4Dept. Chem.,
Grad. Sch. Sci., Osaka City Univ., 5IPR, Osaka Univ., 6Dept. Phys., Fac. Sci.,Fukuoka Univ.)
Reactive Coarse-Grained Molecular Dynamics Simulation for the Functional Dynamics of Lambda
Exonuclease
Toru Niina, Shoji Takada (Grad. Sch. Sci. Kyoto Univ.)
マイクロ秒時間領域で形成される一酸化窒素還元酵素反応中間体の分光解析
Characterization of reaction intermediate formed in the microsecond time domain of the catalytic
reaction of nitric oxide reductase
Takehiko Tosha1, Hanae Takeda1,2, Tetsunari Kimura3, Masaki Horitani4, Yoshitsugu Shiro2 (1RIKEN
SPring-8, 2Univ. of Hyogo, 3Kobe Univ., 4Saga Univ.)
PyDISH: Database and analysis tools for heme porphyrin distortion in heme proteins
Yu Takano1, Hiroko X. Kondo1,2,3, Yusuke Kanematsu1,4, Gen Masumoto5 (1Grad. Sch. Info. Sci.
Hiroshima City Univ., 2Faculty of Eng. Kitami Inst. Tech., 3RIKEN BDR, 4Grad. Sch. Adv. Sci. Eng.
Hiroshima Univ., 5RIKEN ISC)
Transient binding and non-rotational coupled motion of p53 revealed by sub-millisecond resolved
single-molecule fluorescence tracking
Dwiky Rendra Graha Subekti1,2, Satoshi Takahashi1,2, Kiyoto Kamagata1,2 (1IMRAM, Tohoku Univ.,
2Grad. Sch. Sci. Tohoku Univ.)
リン脂質二重膜ナノディスクへの再構成に伴うヒト Steap3 の三価鉄還元酵素活性の増強
Enhancement of ferric reductase activity of human Steap3 upon reconstitution into phospholipid
bilayer nanodisc
Ayane Nishi1, Akito Nakata1, Fusako Takeuchi2, Tetsunari Kimura1, Motonari Tsubaki1 (1Dept. of Chem.,
Grad. Sch. Sci., Kobe Univ., 2IPHE, Kobe Univ.)
分子動力学シミュレーションによって明らかになった SLC26A9 の塩素イオン輸送における細胞質ドメインの役割
Role of the cytoplasmic domains of SLC26A9 in chloride ion transport revealed by the molecular
dynamics simulations
Satoshi Omori1, Yuya Hanazono2, Hafumi Nishi1,3, Kengo Kinoshita1,4,5 (1GSIS, Tohoku Univ., 2Inst. for
Quantum Life Sci., QST, 3Faculty of Core Res., Ochanomizu Univ., 4ToMMo, Tohoku Univ., 5Inst. of Dev.
Aging and Cancer, Tohoku Univ.)
Time-resolved spectroscopic measurements on the transport dynamics of ABC transporter
Tetsunari Kimura1,2, Sae Hayashi1, Yuka Ikemoto3, Yoshitsugu Shiro4, Hiroshi Sugimoto2 (1Grad. Sch.
Sci., Kobe Univ., 2RIKEN, SPring-8, 3JASRI, 4Grad. Sch. Sci., Univ. Hyogo)– S64 –

20156B

20157B

20158B

大腸菌 UvrD C 末端 40 アミノ酸欠損変異体の DNA 巻き戻しダイナミクス
DNA-unwinding dynamics of Escherichia coli UvrD lacking the C-terminal 40 amino acids
Hiroaki Yokota (Grad. Sch. Creation New Photon. Indust.)
高速原子間力顕微鏡によるタンパク質膜輸送装置 Sec の動態観察
Observation of Substrate Binding Sec Translocon and Structural Change of SecA with HS-AFM
Wataru Nagaike1, Takamitsu Haruyama2, Tomoya Tsukazaki2, Takayuki Uchihashi1,3 (1Dept of phys,
Nagoya univ, 2NAIST, 3EXCELLS)
Structure of the voltage-dependent potassium channel (hERG) using cryo-electron microscopy
Tatsuki Asai1, Kano Suzuki1, Naruhiko Adachi2, Masato Kawasaki2, Toshio Moriya2, Toshiya Senda2,
Satoshi Ogasawara1, Takeshi Murata1 (1Grad. Sch. Sci., Univ. Chiba, 2KEK, Tsukuba)
C. 核酸:構造・物性・相互作用・複合体／C. Nucleic acid20159C

20160C
20161C*

20162C

20163C*

20164C

20165C

20166C

20167C*

20168C20169C*

状態遷移機械を実装する多段階 DNA コンピューティング反応の最適化
Optimization of the multi-step DNA computing reaction that implements a state machine
Shuntaro Sato1, Masayuki Yamamura2, Ken Komiya2 (1Sch. Life Sci. Tech., Tokyo Inst. Tech., 2Sch.
Comp., Tokyo Inst. Tech.)
演題取り消しDNA のメチル化パターン依存的な構造動態の解析
Structural Dynamics of DNA Depending on Methylation-Patterns
Takeru Kameda1,2, Miho M. Suzuki3, Akinori Awazu4, Yuichi Togashi2,4 (1Graduate School of Science,
Hiroshima University, 2RIKEN Center for Biosystems Dynamics Research, 3Graduate School of Medicine,
Nagoya University, 4Graduate School of Integrated Sciences for Life, Hiroshima University.)
クロマチンドメインのエントロピー駆動相分離による染色体コンパートメント形成
Entropic phase separation of chromatin domains to form chromosome compartments
Shin Fujishiro, Masaki Sasai (Grad. Sch. Appl. Phys., Nagoya Univ.)
分子動力学計算による p53-C 末端部位の DNA 結合機構の解明
DNA binding mechanisms of the p53 C-terminal domain elucidated by MD simulation
Yuta Taira, Duy Tran, Akio Kitao (Titech)
DNA curtain assay of nucleosome repositioning and collisions induced by translocases
Fritz Nagae, Shoji Takada, Tsuyoshi Terakawa (Department of Biophysics, Graduate School of Science,
Kyoto University)
核膜近傍におけるクロマチン構造形成と RNA 輸送モデルの構築
Model construction of chromatin structure formation and RNA transport near the nuclear
membraneNozomu Imai, Shin Fujishiro, Masaki Sasai (Dept. Appl. Phys., Nagoya Univ.)
ArsInsC 配列及び DNA 反復配列の物理的特性・機能性解析
Analysis of physical properties and functionalities of ArsInsC and DNA repeat sequences
Tappei Oda, Masashi Fujii, Naoaki Sakamoto, Akinori Awazu (Dept. of math. and life sci. Hiroshima
Univ.)
並列的な自己集合を基盤とした DNA 演算のナノポアデコーディング
Nanopore decoding for DNA computing based on parallel self-assembly
Sotaro Takiguchi, Ryuji Kawano (Department of Biotechnology of Life Science, Tokyo University ofAgriculture and Technology)
Local chromatin motion, chromatin quantity and nuclear volume
Shiori Iida1, Yuji Itoh2, Kayo Hibino1,2, Kazuhiro Maeshima1,2 (1Dept. of Genetics, Sch. of Life Sci.,
SOKENDAI, 2Genome Dynamics Lab., Natl. Inst. of Genetics)
分子動力学シミュレーションによる転写開始複合体の全原子構造モデリング
Modeling Atomistic Structure of Transcription Initiation Complex with DNA Bubble by Molecular
Dynamics Simulation
Genki Shino, Shoji Takada (Dept. of Biophys., Div. of Bio. Sci., Grad. Sch. of Sci., Kyoto Univ.)– S65 –

20170C

20171C*20172C*

Toward the construction of artificial organelles with controllability based on liquid-liquid phaseseparation of DNA nanostructures
Yusuke Sato (Frontier Research Institute for Interdisciplinary Sciences, Tohoku University)
DNA によるミクロ相分離 droplet の安定化と新しい人工細胞系の検討
Stabilization of micro phase-separated droplet and examination of new artificial cell system
Moe Yabuta, Yoshihiro Minagawa, Hiroyuki Noji (Department of Applied Chemistry, Graduate School ofEngineering, University of Tokyo)
Large scale simulation of DNA hydrogel
Marcos Masukawa1, Masahiro Takinoue1,2 (1Tokyo Inst. of Tech., Dept. of Comp. Sci., Sch. of Artif. Intel.,
2Tokyo Inst. of Tech., Dept. of Comput. Intel. and Syst. Sci.)
D. 電子状態／D. Electronic state20173D

銅アミン酸化酵素のプロトン化状態についての QM/MM 解析
QM/MM study for the protonation states of copper amine oxidase
Mitsuo Shoji1,2, Takeshi Murakawa3, Yasuteru Shigeta1, Hideyuki Hayashi3, Toshihide Okajima3,4 (1Univ.
Tsukuba, 2JST-PRESTO, 3Osaka Medical College, 4Osaka Univ.)
E. 水・水和・電解質／E. Water, Hydration & Electrolyte

20174E20175E20176E20177E20178E*20179E

20180E

Application of a Deep-Learning Technique to Predict the Hydration Structure around Proteins
Kosuke Kawama1, Takashi Yoshidome1, Mitsunori Ikeguchi2,3, Masateru Ohta2 (1Dep. of Appl. Phys.,
Tohoku Univ., 2RIKEN, 3Grad. Sch. of Med. Life Sci., Yokohama City Univ.)
リガンド結合サイトにおける水和の包括的解析：3D-RISM 理論アプローチ
Comprehensive Analysis of the Hydration of Small Molecule Binding Sites in Ligand-Free Protein
Structures: 3D-RISM Approach
Takashi Yoshidome1, Mitsunori Ikeguchi2,3, Masateru Ohta2 (1Dep. of Appl. Phys., Tohoku Univ., 2RIKEN,
3Grad. Sch. of Med. Life Sci., Yokohama City Univ.)
Analysis of urea effect for binding free energy of lysozyme-(GlcNac)3
Simon Hikiri, Nobuyuki Matubayasi (Grad. Sch. Eng. Sci., Osaka Univ.)
Simulation-based machine-learning approach for the water dynamics
Taku Muzukami1, Viet Cuong Nguyen3, Hieu Chi Dam2 (1Materials Science, JAIST, 2Knowledge Science,
JAIST, 3HPC systems Inc)
MED26 による TAF7 と EAF1 認識における多様な結合様式に関する分子動力学研究
Molecular dynamics study on the multiple binding modes of MED26 torecognize EAF1 and TAF7
Satoshi Goto1, Kota Kasahara2, Hidehisa Takahashi3, Hidehisa Takahashi2 (1Grad. Sch., Life Sci.,
Ritsumeikan Univ., 2Coll. Life Sci., Ritsumeikan Univ., 3Grad. Sch. Med., Yokohama City Univ.)
ヌクレオチド三リン酸の結合による細胞混雑中の蛋白質間相互作用の減少
Reduced protein-protein interactions in the cellular crowding with binding of nucleoside
triphosphates
Isseki Yu1, Michael Feig2, Yuji Sugita3 (1Maebashi Institute of Technology, 2Michigan State University,
3RIKEN Theoretical Molecular Science Lab.)
異なる配列と構造のペプチド周囲の水和ダイナミクスを MD シミュレーションで明らかにする
MD simulations reveal hydration dynamics around peptides with different sequences andstructures
Takuya Takahashi1, Shingo Nobunaga1, Takuya Azami2, Ryoi Ashida2, Takuya Fujisawa2,
Kota Kasahara1 (1Coll. Life Sci., Ritsumeikan Univ., 2Grad. Sch., Life Sci., Ritsumeikan Univ.)– S66 –

20181E

分子動力学法を用いたポリグルタミン酸周囲の水和ダイナミクス解析
Analysis of hydration dynamics around polyglutamic acid using molecular dynamics method
Takuya Fujisawa1, Takuya Takahashi2, Kota Kasahara2 (1Grad. Sch. Life Sci., Ritsumeikan Univ., 2Coll.
Life Sci., Ritsumeikan Univ.)
F. 分子遺伝・遺伝情報・制御・発生・分化／F. Molecular genetics & Development

20182F20183F*20184F

Loop extrusion of chromatin at surfaces modulates the growth dynamics of transcriptionalcondensates
Tetsuya Yamamoto1,2, Helmut Schiessel3 (1Institute for Chemical Reaction Design and Discovery,
Hokkaido University, 2PRESTO, JST, 3Instituut-Lorentz for theoretical physics, Universiteit Leiden)
細胞性粘菌の脱分化過程における細胞質 pH の測定
Measurement of cytosolic pH changes during dedifferentiation of Dictyostelium cells
Tomomi Usui1, Yusuke Morimoto2 (1Dept. Biosci. Bioinfo., Fac. Comp. Sci. and Sys. Eng., Kyushu Inst.
Tech., 2Dept. Phys. and Info. Tech., Fac. Comp. Sci. and Sys. Eng., Kyushu Inst. Tech.)
合成遺伝子回路における細胞間相互作用依存的な発現と分化多能性
Cell-cell interaction-dependent expression of a synthetic genetic circuit and its relevance topluripotency
Kei Ikemori1, Yuichi Wakamoto2 (1Col. of Art. & Sci., Univ. Tokyo, 2Grad. Sch. of Arts. & Sci., Univ.
Tokyo)
G. 筋肉・分子モーター／G. Muscle & Molecular motor

20185G

20186G

20187G

20188G

20189G

小胞輸送を担う分子モーターの分子数とダイニン阻害剤の影響
Effect of the dynein inhibitor dynarrestin on the number of motor proteins transporting synaptic
cargosKumiko Hayashi1,3, Miyamoto Miki1, Shinsuke Niwa2 (1Grad. Sch. Eng., Tohoku Univ., 2FIRS, Tohoku
Univ., 3JST, PRESTO)
X 線繊維回折解析による真核生物鞭毛軸糸の Ca2+濃度依存的らせん対称性変化[Ca2+]-dependent changes in the helical symmetry of Chlamydomonas and Ciona flagellar
axonemes revealed by X-ray fiber diffraction
Kazuhiro Oiwa1, Kenta Ishibashi1,2, Kogiku Shiba3, Kazuo Inaba3, Hiroyuki Iwamoto4,
Hitoshi Sakakibara1 (1Nat. Inst.Info.Commun.Technol, 2Osaka Univ. CiNet, 3Shimoda Marine Res. Cent.
Univ. Tsukuba, 4JASRI, SPring-8)
KIF1A/UNC-104 によるシナプス小胞前駆体輸送の数理モデル 2
Mathematical modeling of synaptic vesicle precursor transport by KIF1A/UNC- 104 2
Ryo Sasaki1, Ryota Shinagawa1, Kimiko Nagino1, Kazuo Sasaki1, Shinsuke Niwa2, Kumiko Hayashi1,3(1Dep. Appl. Phys., Grad. Sch. of Eng., Tohoku Univ., 2FRIS, Tohoku Univ., 3JST, PRESTO)
Computer simulation of molecular shuttles driven by biomolecular motors in external force field
Sweet May1, Takahiro Nitta1,2 (1Electronic and Information Systems Engineering Division, Faculty ofEngineering, Gifu University, 2Applied Physics Course,Faculty of Engineering, Gifu Univerisity)
The Impact of Defective Motors on Biosensor Integrated with Actin Filaments and Myosin
Samuel Macharia Kang'iri1, Takahiro Nitta1,2 (1ELECTRONICS AND INFORMATION SYSTEMSENGINEERING DIVISION, FACULTY OF ENGINEERING, GIFU UNIVERSITY, 2APPLIED PHYSICSCOURSE, FACULTY OF ENGINEERING, GIFU UNIVERSITY)– S67 –

20190G*

20191G

20192G

20193G

20194G

20195G

20196G

20197G

20198G

20199G

キネシン分子の空間配置が輸送複合体の運動に与える影響の評価
Molecular layout of kinesin affects the collective movement of DNA origami-based transportcomplex
Kodai Fukumoto1, Yuya Miyazono2, Hisashi Tadakuma3, Yoshie Harada1 (1IPR, Osaka Univ., 2Grad. Sch.
Front. Sci., Univ. Tokyo, 3SLST, ShanghaiTech Univ.)
キネシン・ダイニンによる軸索輸送速度の極値統計解析
Extreme value analysis of axonal transport velocity of kinesins and dyneins
Takuma Naoi1, Kimiko Nagino1, Kazuo Sasaki1, Shinsuke Niwa2, Kumiko Hayashi1,3 (1Dep. Appl. Phys.,Grad. Sch. Eng., Tohoku Univ., 2FRIS, Tohoku Univ., 3JST, PRESTO)
外眼筋の X 線回折像に対する BDM の効果
Effect of BDM on the structure of extraocular muscle revealed by x-ray diffraction
Maki Yamaguchi1, Tohru Kurihara1, Naoya Nakahara1, Tetsuo Ohno2, Toshiko Yamazawa1,
Hideki Yamauchi1, Kazuhiro Hirano1, Takuhiro Kawahara1, Shigeru Takemori1 (1Dept. Mol.Physiol., The
Jikei Univ. Sch. Med., 2Sports Med., Teikyo Heisei Univ.)
1 分子・多分子実験から迫る、心機能に特化した心筋ミオシンの性質
Molecular properties of single cardiac myosin adapted for heart functions revealed by single- andmulti-molecule approaches
Yongtae Hwang1, Takumi Washio2,3, Toshiaki Hisada2, Hideo Higuchi1, Motoshi Kaya1 (1Department of
Physics, The University of Tokyo, 2Future Center Initiative, The University of Tokyo, 3UT-Heart Inc.)
ウシミトコンドリア由来 ATP 合成酵素の内在性阻害因子 IF1 の 阻害機構解明
Elucidation of inhibition mechanism by IF1, a natural inhibitor protein for bovine mitochondrial ATP
synthase
Ryohei Kobayashi, Sougo Mori, Hiroshi Ueno, Hiroyuki Noji (Appl. Chem., Grad. Sch. Eng., Univ. Tokyo)
The N-terminal β-strand of single-headed kinesin-1 is involved in the off-axis force-generation andresultant rotation pitch
Masahiko Yamagishi1, Shoko Fujimura2, Mitsuhiro Sugawa1, Takayuki Nishizaka2, Junichiro Yajima1(1Dept. Life Sci., Grad. Arts & Sci., Univ. Tokyo, 2Dept. Physics, Gakushuin Univ.)
心筋サルコメアにおける Fhod3 と cMyBP-C の同定
Identification of Fhod3 and cMyBP-C in cardiac sarcomere
Wataru Kedouin1, Riho Takiiwa1, Nao Shimojo1, Ryu Takeya2, Takuo Yasunaga1 (1Kyushu Inst. of Tech.,
2Univ.of Miyazaki)
キネシンと微小管による印刷可能な人工筋肉のコンピュータシミュレーション
Computer simulation of printable artificial muscles composed of engineered kinesins andmicrotubules
Yurino Aoyama1, Yuichi Hiratsuka2, Takahiro Nitta3 (1Grad. Sch. Appl. Math. Phys., Gifu Univ., 2Sch.
Materials Sci., JAIST, 3Appl. Phys. Course, Faculty of Eng., Gifu Univ.)
ウニ胚形態形成の細胞骨格観察に基づくモデル化
Modeling of sea urchin gastrulation based on cytoskeleton imaging
Kaichi Watanabe1, Yuta Kurose2, Yuhei Yasui1, Naoaki Sakamoto1, Akinori Awazu1 (1Grad. Sch. ofIntegrated Sciences for Life, Univ. Hiroshima, 2Grad. Sch. Sci, Univ. Hiroshima)
ATP 合成酵素の c リングの回転は c サブユニットでのプロトンの受け取りと放出および a サブユ
ニットとの静電相互作用が協調して引き起こされる
Cooperation of proton release/uptake and electrostatic interaction between a subunit and csubunit drive c-ring rotation in ATP synthase
Noriyo Mitome1,2,3, Shintaroh Kubo4, Sumie Ohta2, Hikaru Takashima3, Yuto Shigefuji3, Toru Niina4,
Shoji Takada4 (1Fac. of Educ., Tokoha Univ., 2Dept. of Chem. and Biochem., Natn. Inst. of Tech., Numazu
coll., 3Dept. of Chem. and Bio. Engin., Natn. Inst. of Tech., Ube coll., 4Dept. of Biophys., Grad. School of
Sci., Kyoto Univ.)– S68 –

20200G

20201G

20202G

20203G

20204G

20205G

20206G

20207G*

20208G

20209G

20210G

Performance of step-finding algorithm based on the Schwarz Information Criterion depends onnoise and data points per dwell-time
Monique Honsa1,2, Kimitoshi Takeda2, Akihiro Otomo2,3, Hanjin Liu4, Tomohiro Shima4, Ryota Iino2,3(1LMU Munich, 2IMS, 3SOKENDAI, 4U Tokyo)
自由エネルギーランドスケープのスイッチングとパワーストロークを考慮した筋収縮の三状態モ
デル
Three-state model of muscle contraction with switched free energy landscapes and power stroke
Kaima Matsuda, Masaki Sasai, Tomoki P. Terada (Dept. Appl. Phys., Grad. Sch. Eng., Nagoya. Univ.)
体温に温めた心筋細胞に備わる収縮リズム恒常性
Contraction Rhythm Homeostasis in cardiomyocytes warmed to body temperature
Seine A. Shintani (Dep. of Biomedical Sci., College of Life and Health Sci., Chubu Univ.)
電子顕微鏡構造解析により明らかにされた細胞質ダイニンの休止状態の解除メカニズム
Release mechanism of the shutdown state of cytoplasmic dynein revealed by electron microscopy
Kazuki Iwasaki1, Yui Kurume1, Hiroshi Imai1, Shinji Kamimura2, Rieko Shimo-kon1,
Ryosuke Yamamoto1, Takahide Kon1 (1Grad. Sch. Sci., Osaka Univ, 2Dept.Biol.Sci.,huo Univ.)
動く幽霊~高度好塩菌ハロフェラックス・ボルカニ~
Motile ghosts of the halophilic archaeon, Haloferax volcanii
Yoshiaki Kinosita1,2, Richard Berry2 (1Molecular Physiology Lab., RIKEN, 2Department of Physics,
University of Oxford)
汎用 3 次元モデリングソフトウェア Blender を利用したタンパク質超分子構造の動的性質の理解
Understanding Supermolecular Structure and Dynamic Property of Proteins using a general
purpose 3D Graphics Modeling Software Blender
Yutaka Ueno1, Kaoru Katou1, Akira Kakugo3, Kento Matsuda3, Akihiko Konagaya2 (1AIST Tokyo, 2Tokyo
Tech., Dept. of Computer Scinence, 3Hokkaido Univ., Graduate School of Chemical Science andEngineering)
NMR による海洋性ビブリオ菌べん毛モーターの回転方向を制御する回転子タンパク質 FliG の構造変化の解析
NMR analysis of the conformational change in FliG that switches the rotational direction of theflagellar motor in marine bacterium Vibrio
Tatsuro Nishikino1, Seiji Kojima2, Michio Homma2, Yohei Miyanoiri1 (1Inst. for Protein res., Osaka
Univ., 2Div. Biol. Sci. Grad. Sch. Sci., Nagoya Univ.)
Multiple step photo regulation of mitotic kinesin Eg5 using a novel photochromic Inhibitor
composed of Spiropyran and azobenzene
Islam Md Alrazi, Kei Sadakane, Happy Ogunwa Tomisin, Shinsaku Maruta (Soka University, Graduate
School of Engineering, Department of Bioinformatics)
Modeling of condensin hinge/DNA structure by molecular dynamics simulations guided by atomic
force microscopy
Hiroki Koide1, Noriyuki Kodera2, Shveta Bisht3, Christian Haering3, Shoji Takada1, Tsuyoshi Terakawa1(1Department of Biophysics, Graduate School of Science, Kyoto University, 2Nano Life Science Institute(WPI-NanoLSI), Kanazawa University, 3Cell Biology and Biophysics Unit, Structural and Computational
Biology Unit, European Molecular Biology Laboratory (EMBL))
キネシン 1 二量体の前頭部における微小管からの解離抑制の直接観察
Direct observation of the suppression of the leading head of kinesin-1 dimer from detachment frommicrotubule
Kohei Matsuzaki1,2, Michio Tomishige1 (1Dept. Phys., Col. Sci. Eng., Aoyama Gakuin Univ.,, 2Dept. Appl.
Phys., Grad. Sch. Eng., Univ.Tokyo)
ミオシン VI の歩行運動に対するランドスケープ描像
A landscape-based view on the stepping movement of myosin VI
Tomoki P. Terada1, Qing-Miao Nie2, Masaki Sasai1 (1Dept. Appl. Phys., Grad. Sch. Eng., Nagoya Univ.,
2Dept. Appl. Phys., Zhejiang Univ. Tech.)– S69 –

20211G

20212G*

20213G

20214G

20215G*

20216G

20217G

20218G

20219G

20220G

20221G*

20222G*

微小管とキネシンの結合におけるチューブリン C 末端の役割
Role of C-terminal tail of tubulin in microtubule-kinesin binding
Yuta Taguchi, Yukinobu Mizuhara, Jun Ohnuki, Mitsunori Takano (Dept. of Pure & Appl. Phys., Waseda
Univ.)
べん毛モーター固定子の協働的な集合によるトルクの自律的制御
Cooperative stator assembly of bacterial flagellar motor for autonomous torque regulation
Kenta Ito, Shuichi Nakamura, Shoichi Toyabe (Grad. Eng., Tohoku Univ.)
光てこによる Volvox1 個体が生じる推進力の直接測定
Direct force measurement of a swimming Volvox spheroid by a high-speed optical lever system
Katsuya Shimabukuro1, Kosaku Horinaga1, Kazumo Wakabayashi1, Hikaru Emoto1, Noriko Ueki2,
Ken-ichi Wakabayashi3, Noriyo Mitome1,4 (1Chem. Bio. Eng., NIT Ube College, 2Sci. Res. Cent., Hosei
Univ, 3CLS, Tokyo Tech, 4Tokoha Univ.)
高速イメージングで明らかになった遊泳するボルボックスの速度周期性
Periodic fluctuations detected in the swimming velocity of a Volvox carteri spheroid by high speed
imaging
Naoki Uemura, Tatsuya Suehiro, Midori Nosaka, Katsuya Shimabukuro (Chem. Bio. Eng., NIT Ube
College)
好熱菌由来 F1-ATPase の完全な化学力学共役は至適生育温度において破れる
The perfect mechanochemical coupling of thermophilic F1-ATPase breaks at the optimum growthtemperature
Tomoaki Okaniwa1, Yohei Nakayama1,2, Eiro Muneyuki1 (1Grad. Sch. Sci. Eng., 2Grad. Sch. Eng.)
ATP 加水分解を選択的に抑制する F1-ATPase の速度論的制御機構
Kinetic ratchet mechanism of F1-ATPase selectively suppresses hydrolysis of ATP
Yohei Nakayama, Shoichi Toyabe (Grad. Sch. Eng., Tohoku Univ.)
Mixed motility assay を用いたフォトクロミック Eg5 阻害剤の Eg5 阻害機構の解析
Analyze inhibitory mechanism of kinesin Eg5 with photochromic Eg5 inhibitor using mixed-motility
assay
Kei Sadakane1, MD Alrazi Islam2, Happy Ogunwa Tomisin2, Shinsaku Maruta1,2 (1Sci. & Eng., Soka
Univ., 2Grad. Sch. Eng., Soka Univ.)
DNA ナノチューブ上に構築されたダイニン線形アレイの集団運動性
Collective motility of dynein linear arrays built on DNA nanotubes
Ryota Ibusuki1, Misaki Shiraga2, Akane Furuta1, Maki Yoshio1, Hiroaki Kojima1, Kazuhiro Oiwa1,2,
Ken'ya Furuta1 (1Adv. ICR. Res. Ins., NICT. Kobe, 2Grad. Sch. Sci., Univ. Hyogo)
Increasing speed of single-molecule kinesin movement in vitro
Keitaro Shibata1, Misaki Sagawa2, Hiroaki Kojima1, Ken'ya Furuta1 (1Adv. ICT. Res. Ins., NICT, 2Grad.
Sch. Sci., Univ. Hyogo)
Single-molecule analysis of artificial kinesin-1 dimers and trimers with different linker lengths
Kimitoshi Takeda1, Monique Honsa1,2, Akihiko Nakamura3, Jun Ando4, Ryota Iino1,5 (1Institute for
Molecular Science, 2LMU Munich, 3Dep. Appl. Life Sci. Agr. Shizuoka Univ, 4RIKEN, 5SOKENDAI)
バーチャル電極上の電場によるキネシンと微小管の駆動システムの制御
Controlling fundamental functions of the kinesin-microtubule by the electrical field on the virtual
cathodeKenta Hatazawa1, Ryuzo Kawamura2, Takayuki Hoshino1 (1Department of Mechanical Science andEngineering, Science and Technology, Hirosaki Univ., 2Division of Strangic Research and Development,
Graduate School of Science and Engineering, Saitama Univ.)
ダイナクチンサイドアームのコンフォメーション多様性
Conformational diversity of dynactin sidearm
Kei Saito1, Takuya Kobayashi2, Takashi Murayama2, Yoko Toyoshima1 (1Grad. Sch. Arts Sci., Univ.
Tokyo, 2Dept. of Pharmacology, Juntendo Univ. Sch. of Med.)– S70 –

20223G

20224G

20225G*

20226G

20227G

20228G*
20229G

20230G

20231G

20232G

20233G

20234G*

Constructing a simplified axoneme-like system using Chlamydomonas outer arm dynein and DNA
nanotubes
Akane Furuta1,2, Yuka Matsuda3, Ryota Ibusuki1, Misaki Sagawa3, Kazuhiro Oiwa1,3, Hiroaki Kojima1,
Ken'ya Furuta1 (1NICT, 2JSPS, 3University of Hyogo)
V/A-ATPase の膜内在性ドメイン Vo のプロトン漏洩防止機構
Mechanical inhibition of isolated Vo from V/A-ATPase for proton conductanceJun-ichi Kishikawa1,2, Atsuko Nakanishi3, Aya Furuta2, Takayuki Kato1, Keiichi Namba4,
Masatada Tamakoshi5, Kaoru Mitsuoka2, Ken Yokoyama2 (1Inst. Prot. Res., Osaka Univ., 2Dept. Mol.
Biosci., Kyoto Sangyo Univ., 3Res. Ctr. UHVEM., Osaka Univ., 4Grad. Sch. Frontier. Biosci., Osaka Univ.,
5Dept. Mol. Biol., Tokyo Univ. Pharm. Life Sci.)
FliL は低負荷条件下で大腸菌べん毛モーターの回転を支援する
FliL assists flagellar motor rotation in Escherichia coli under low load condition
Tsubasa Ishida1, Myu Yoshida2, Tohru Minamino3, Yoshiyuki Sowa1,2,4 (1Grad. Sch. Sci. & Eng., Hosei
Univ., 2Dept. Frontier Biosci., Hosei Univ., 3Grad. Sch. Frontier Biosci., Osaka Univ., 4Res. Cent. MicroNano Tech., Hosei Univ.)
Enterococcus hirae 由来 V-ATPase のナトリウムイオン濃度に依存した回転運動の 1 分子解析
Single-molecule analysis of rotation of Enterococcus hirae V-ATPase depending on sodium ion
concentration
Akihiro Otomo1,2, Tatsuya Iida1,2, Hiroshi Ueno3, Takeshi Murata4, Ryota Iino1,2 (1Inst. for. Mol. Sci,
2SOKENDAI, 3The Univ. Tokyo, 4Chiba Univ.)
Autonomous molecular swarm robots realized by sequential transfer of DNA signal
Jakia Jannat Keya1, Yuta Yamasaki2, Kazuki Sada1, Akinori Kuzuya2, Akira Kakugo1 (1Hokkaido
University, 2Kansai University)
演題取り消し鞭毛波形切り替えメカニズムの数理モデル
A mathematical model for mechanism of flagellar waveform change
Kenta Ishibashi1,2, Hitoshi Sakakibara3, Kazuhiro Oiwa2,3,4 (1Osake Univ., 2NICT-CiNet, 3Advanced ICT
Research Institute, 4University of Hyogo)
The Helical Arrangement of Axonemal Structures Depends on the Region of the Flagellum
Hitoshi Sakakibara1, Kenta Ishibashi2, Hiroyuki Iwamoto3, Hiroaki Kojima1, Kazuhiro Oiwa1,4 (1BioFunction PJ, NICT, 2CiNet, Osaka Univ., 3SPring-8, JASRI, 4Life Sci. Univ. Hyogo)
ビーズ-DNA 複合体および DNA ナノチューブを利用した人工分子モーターの実現を目指して
Towards the realization of artificial molecular motor using beads-DNA complex and DNA nanotube
Kohei Arai1, Kenta Ito1, Yuki Tsushima2, Yusuke Sato1,3, Shoichi Toyabe1 (1Appl. Phys., Grad. sch. eng.,
Tohoku univ, 2IIS, Tohoku univ., 3Front. Res. Inst. Interdiscip. Sci., Tohoku Univ)
単極毛性細菌 Vibrio cholerae におけるべん毛モーター回転切り替えの協同性
Low cooperativity of flagellar motor switching in Vibrio cholerae the bacterium of a single polar
flagellum
Hirotaka Tajima1,2, Masatoshi Nishikawa1, Yuki Miura3, Yoshiyuki Sowa1,2,3, Ikuro Kawagishi1,2,3(1Dept. Front. Biosci., Hosei Univ., 2Res. Cent. Micro-Nano Tech., Hosei Univ., 3Grad. Sch. Eng., Hosei
Univ.)
CbM4 の持つ時計回りの運動活性の解析
Analysis of the clockwise motility of CbM4
Kohei Yoshimura, Takuma Imi, Takeshi Haraguchi, Masanori Tamanaha, Kohji Ito (Grad. Sch. Sci.,
Chiba Univ.)
腸管病原性大腸菌が有するⅢ型分泌装置の ATPase の活性特性評価と HS-AFM を用いた構造ダイ
ナミクスに対する考察
Characterization of the enzymatic property and structural dynamics of the T3SS ATPase fromEnteropathogenic Escherichia coli
Aya Suzuki1, Hiroshi Ueno1, Ryo Kurosaki2, Takayuki Uchihashi2, Hiroyuki Noji1 (1Grad. Sch. Eng.,
Univ. Tokyo, 2Grad. Sch. Sci., Univ. Nagoya)– S71 –

H. 細胞生物学的課題（接着,運動,骨格,伝達,膜）／H. Cell biology
20235H
20236H
20237H
20238H

20239H

20240H

20241H*

20242H

20243H*

20244H

20245H

20246H

20247H

20248H

演題取り消し演題取り消しVisualizing of neo-self phenomena in chimeric antigen receptor (CAR)-T cells
Hiroaki Machiyama, Ei Wakamatsu, Tadashi Yokosuka (Dept. Immunol, Tokyo Med. Univ.)
ストレスファイバーの張力ホメオスタシスに関する研究
Theoretical consideration of homeostasis in stress fibers
Yuika Ueda, Daiki Matsunaga, Tsubasa Matsui, Shinji Deguchi (Grad. Eng. Sci., Univ. Osaka)
支持脂質二重膜に固定したカドヘリンのモノマー・ダイマー間構造変換の高速 AFM による追跡
Chasing the transformation between monomer and dimer structure of cadherin anchored tosupported lipid bilayer by high-speed AFM
Shigetaka Nishiguchi1, Hiroki Oda3,4, Takayuki Uchihashi1,2 (1ExCELLS, 2Nagoya Univ., 3BRH, 4Osaka
Univ.)
非接着状態がん細胞の転移能上昇に伴う細胞間接着強度の増加
Increase of intercellular adhesion strength of non-adherent cancer cells associated with theupregulation of their metastatic ability
Kenta Ishibashi1, Chikashi Nakamura1,2, Hyonchol Kim1,2 (1Grad. Sch. Eng., Tokyo Univ. Agric. Technol.,
2Cell. Mol. Biotechnol. Res. Inst., AIST)
損傷した細胞における細胞内粘性と生存確率の関係
Cytoplasmic Viscosity and Cellular Viability of the Damaged Cells
Hideaki Ota, Hideo Higuchi (Department of Physics, School of Science, The University of Tokyo)
繊毛への機械刺激依存的な、マウスノードクラウン細胞における mRNA 分解
Mechanical stimuli to a cilium activate mRNA decay in a mouse nodal crown cell
Takanobu A Katoh1, Katsutoshi Mizuno1,2, Hiroshi Hamada1 (1BDR, Riken, 2School of Medical Sciences,
University of Fukui)
運動性細胞における Ras の興奮性制御に関わる GEF の同定
Identification of GEFs regulating the excitability of Ras in motile cells
Koji Iwamoto1, Satomi Matsuoka1,2,3, Masahiro Ueda1,2,3 (1Grad. Sch. Sci., Univ. Osaka, 2Grad. Sch. of
Front. Biosci., Univ. Osaka, 3BDR, RIKEN)
クラミドモナス軸糸運動の再活性化イメージング
High hydrostatic pressure induces vigorous flagellar beating in Chlamydomonas non-motile
mutants lacking the central apparatus
Toshiki Yagi1, Masayoshi Nishiyama2 (1Pref. Univ. Hiroshima, 2Kindai Univ.)
細菌バイオフィルムと骨代謝の ASEM 免疫電顕と cryo-TEM による観察
Observation of biofilm and bone metabolism in aqueous liquid using immuno-labeled ASEM andcryo-TEM
Chikara Sato1, Shinya Sugimoto2, Eiko Sakai3, Mari Sato1, Naoki Kasahata1, Masami Naya1 (1Health &Medical Res.Inst, AIST., 2Dept. Bacteriol., The Jikei Univ. Sch. Med., 3Dental Pharmacology,Nagasaki
Univ.)
Tension at adherens junction inhibits proliferation and promotes differentiation of keratinocyte
carcinoma cells
Oleg Dobrokhotov, Masahiro Sokabe, Hiroaki Hirata (Grad. Sch. Med., Nagoya Univ.)
細胞質中における p52SHC は GRB2 の細胞膜移行を負に制御する
p52SHC in the cytoplasm negatively regulates GRB2 translocation to the plasma membrane
Ryo Yoshizawa1,2, Nobuhisa Umeki2, Masayuki Murata1, Yasushi Sako2 (1Grad.sch.arts and ahi., the univ.
Tokyo, 2Wako Inst., Riken)
細胞内脂肪滴の普遍的相挙動
Liquid-liquid crystal phase transitions in intracellular lipid droplets
Shunsuke F. Shimobayashi1, Yuki Ohsaki2 (1Chemical Biological Engineering, Princeton Univ., 2Grad.
Sch. Med., Nagoya Univ.)– S72 –

20249H

20250H

20251H

20252H*

20253H*

20254H

20255H

20256H

20257H

20258H*

20259H

20260H

陰圧条件下における金魚ケラトサイト細胞の移動速度の上昇
Enhanced movement of fish keratocyte cells under negative pressure conditions
Akihiro Yamazaki, Hitoshi Tatsumi (Kanazawa Inst. of Technology)
1 細胞自律的な細胞内温度制御の分子機構
A cell-autonomous control of intracellular temperature by mitochondrial thermogenesis
Akira Murakami1,2, Kohjiro Nagao1, Reiko Sakaguchi1, Kohki Okabe2, Harada Yoshie3, Masato Umeda1(1Dept. of Synth. Chem. And. Biol. Chem., Grad. Sch. of. Eng., Kyoto Univ., 2Grad. Sch. of Pharm. Sci.,
Univ. of Tokyo, 3Inst. for Protein Res., Osaka Univ.)
蛍光顕微鏡法による単一デスミンフィラメントの可視化
Visualization of single desmin filaments by fluorescence microscopy in vitro
Masashi Sato, Keigo Murakami, Kuniyuki Hatori (Grad. Sch. Sci. Eng., Yamagata Univ.)
収縮するアクトミオシン構造の綱引きで決まる細胞サイズ液滴内の位置対称性
A tug-of-war between contractile actomyosin structures determines the positioning symmetry incell-sized droplets
Ryota Sakamoto1, Tetsuya Hiraiwa2,3, Masatoshi Tanabe4, Kazuya Suzuki4,5, Shin'ich Ishiwata4,
Yusuke Maeda1, Makito Miyazaki6,7,8 (1Dept. Phys., Kyushu Univ., 2Dept. Phys., Tokyo Univ.,
3Mechanobio. Inst., Nat. Univ. Singapore, 4Dept. Phys., Waseda Univ., 5Cent. Lab., Hamamatsu Photonics
K.K, 6Hakubi Cent., Kyoto Univ., 7Dept. Phys., Kyoto Univ., 8Curie Inst.)
NF-κB mediated transcriptional regulation in B-cell
Johannes Nicolaus Wibisana1, Takehiko Inaba2, Yasushi Sako2, Mariko Okada1 (1IPR Osaka Univ.,
2RIKEN)
神経シナプスでの AMPA 受容体数密度の動的制御：1 分子イメジングによる解明
Dynamic regulation of the AMPA receptor number density in the neuronal synapse as revealedby single-molecule imaging
Yuri L. Nemoto1, Kazuma Naito2, Hiroko Hijikata1, Taka A. Tsunoyama1, Nao Hiramoto-Yamaki2,
Rinshi S. Kasai3, Yuki M. Shirai2, Manami S. Miyahara2, Takahiro K. Fujiwara2, Akihiro Kusumi1,2,3(1OIST, 2Kyoto University, WPI-iCeMS, 3Kyoto University, Institute for Frontier Life and Medical Sciences)γ-tubulin は中心子トリプレット微小管形成に寄与する
γ-tubulin functions in assembling centriolar triplet microtubules
Yuki Nakazawa1,2, Mao Horii3, Saki Watanabe2, Moeko Otsuki2, Akira Noga3, Ken-ichi Wakabayashi4,
Masafumi Hirono2 (1Science and Technology Group, OIST, 2Dept. Frontier Biosci.,Fac. Biosci. Appl.
Chem., Hosei Univ., 3Dept. Biosci., Grad. Sch. Sci., Univ. Tokyo, 4Inst. Innov. Res., Tokyo Inst. Tech.)
2 本の内べん毛の同調した回転は細菌の遊泳を制御する
Coordinated rotation of dual endo-flagella controls bacterial swimming
Toshiki Kuribayashi, Shuichi Nakamura (Grad. Sch. Eng., Tohoku Univ.)細胞の間隙で働く接着性 GPCR の蛍光 1 分子観察
Single molecule observation of adhesion GPCR accumulated at the cell-cell interface
Rinshi Kasai1, Yuri Nemoto2 (1Inst. Front. Life. Med. Sci., Kyoto Univ., 2OIST)
マイクロ構造化ハイドロゲル上を移動する細胞の核形態変化の定量解析
Quantitative analysis of dynamic changes in nuclear morphology in cells migrating on
microstructured gelatin hydrogel
Ryo Ishida1, Tomoko Oyama G2, Kotaro Oyama2, Mitsumasa Taguchi2, Hiromi Miyoshi1 (1Grad. Sch.
Syst., Univ. Tokyo. MetroSyst, 2QuBS., QST)ADP により調節されるマウス気管繊毛の運動活性
Motility of murine tracheal cilia modulated by ADP
Masashi Iwata1, Keiju Kawano1, Masayuki Shiina1, Toshihito Iwase1, Nobukiyo Tanaka1, Koji Ikegami2,
Tomoko Masaike1 (1Dept. of Appl. Biol. Sci., Tokyo Univ. of Science, 2Grad. Sch. of Biomedical & HealthSci., Hiroshima Univ.)
熱量および蛍光滴定により推定されたタウ-DNA 結合熱
Tau-DNA binding heat estimated by calorimetric and fluorescence titrations
Kan Matsuda, Junta Kashima, Hideyuki Komatsu (Dept. Biosci. Bioinf., Kyushu Inst. Tech.)– S73 –

20261H*

20262H

20263H

20264H

20265H

20266H

20267H

20268H

20269H

20270H

クラミドモナス繊毛交互打ち変異株の単離と解析
Isolation and analysis of Chlamydomonas mutants showing alternate ciliary beatings
Kazuma Sakamoto1,2, Toru Hisabori1,2, Ken-ichi Wakabayashi1,2 (1CLS, Tokyo Tech., 2Sch. Life Sci. Tech.,Tokyo Tech.)Response of plural phagocytosis is regulated by the attached order of antigens as far as
macrophages can recognize the time differences
Tomoyasu Sakaguchi1, Yuya Hurumoto1, Tosiki Azuma1, Amane Yosida1, Kenji Yasuda1,2,3 (1Dept. Pure
& Appl. Phys., Grad. Sch. Adv. Sci. & Eng., Waseda Univ., 2Dept. Phys., Sch. Adv. Sci. & Eng., Waseda
Univ, 3Org. Univ. Res. Initiatives, Waseda Univ.)
Dominant factor for cease phagocytosis after excess intake of antigens is explained by the volume
regulation with 0.62-μm encapsulation
Toshiki Azuma1, Yuya Furumoto1, Amane Yoshida1, Tomoyasu Sakaguchi1, Kenji Yasuda1,2,3 (1Dept.
Pure & Appl. Phys., Grad. Sch. Adv. Sci. & Eng., Waseda Univ., 2Phys., Sch. Adv. Sci. & Eng., Waseda
Univ, 3Org. Univ. Res. Initiatives, Waseda Univ.)
Measurement of the temporal rotation change of individual cells’ trajectory in collective cell
migration in agarose microchannels
Shun Koide1, Mitsuru Sentoku1, Kento Iida2, Hiromichi Hashimoto2, Masao Odaka3, Akihiro Hattori3,
Kenji Yasuda1,2,3 (1Dept. Phys., Sch. Adv. Sci. & Eng., Waseda Univ, 2Dept. Pure & Appl. Phys., Grad. Sch.
Adv. Sci. & Eng., Waseda U niv., 3Org. Univ. Res. Initiatives, Waseda Univ.)
Maximum limit of phagocytosis is explained by the shortage of consumable cell membrane with
0.9 μm envelope in phagosome
Dan Horonushi1, Yuya Furumoto2, Toshiki Azuma2, Amane Yoshida2, Tomoyasu Sakaguchi2,
Yumeno Tanaka1, Kenji Yasuda1,2,3 (1Dept. Phys., Sch. Adv. Sci. & Eng., Waseda Univ., 2Dept. Pure &Appl. Phys., Grad. Sch. Adv. Sci. & Eng., Waseda Univ., 3Org. Univ. Res. Initiatives, Waseda Univ)
Velocity split after passing through the wide-narrow-wide capillary tube caused by short-term
memory in collective cell migration
Mitsuru Sentoku1, Hiromichi Hashimoto2, Kento Iida2, Kenji Yasuda1,2,3 (1Dept. Phys., Sch. Adv. Sci. &Eng., Waseda Univ., 2Dept. Pure & Appl. Phys., Grad. Sch. Adv. Sci. & Eng., Waseda Univ., 3Org. Univ.
Res. Initiatives, Waseda Univ.)
PM2.5 antigens maintains efficiency of engulfment ability in serial phagocytosis of single
macrophages with on-chip free-flow method
Yuya Furumoto1, Toshiki Azuma1, Amane Yoshida1, Tomoyasu Sakaguchi1, Yumeno Tanaka2,
Dan Horonushi2, Kenji Yasuda1,2,3 (1Dept. Pure & Appl. Phys., Grad. Sch. Adv. Sci. & Eng., Waseda Univ.,
2Dept. Phys., Sch. Adv. Sci. & Eng., Waseda Univ., 3Org. Univ. Res. Initiatives, Waseda Univ.)
好気及び嫌気性条件で酸化及び還元型 α ディフェンシン cryptdin-4 の抗菌メカニズムの検討
Antibacterial mechanism of an α-defensin, cryptdin-4 in redox status under aerobic and anerobic
conditions
Yi Wang1, Weiming Geng1, Rina Hiramine1, Chisato Toyokawa1, Tomoyasu Aizawa1,2 (1Grad. Sci. Life
Sci., Hokkaido Univ., 2GI-CoRE, Hokkaido Univ.)
多電極電位システムを用いたハイスループット心毒性検査法の実用化を目指した少数心筋細胞集団薬剤応答の解析
Analysis of small size of cardiomyocyte population’s drug response for high-throughput
cardiotoxicity test using multi-electrode system
Kentaro Kito, Naoki Tadokoro, Masahito Hayashi, Tomoyuki Kaneko (Laboratory for Reconstructive Cell
biology, Department of Frontier Bioscience, Hosei University)
大腸菌走化性応答適応過程の高い再現性を実現する簡易培養方法の構築
Construction of simple culture method that realizes high reproducibility of Escherichia coli
chemotaxis response adaptation process
Hiroto Tanaka, Yasuaki Kazuta, Amina Yano, Hiroaki Kojima (Adv ICT Res Inst, NICT)– S74 –

20271H

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20275H

20276H

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20279H

20280H

20281H

Hysteresis is not remained in macrophages after engulfment in fluctuation of movement angles
with a single-point series phagocytosis assay
Yumeno Tanaka1, Yuya Furumoto2, Toshiki Azuma2, Amane Yoshida2, Tomoyasu Sakaguchi2,
Dan Horonushi1, Kenji Yasuda1,2,3 (1Dept. Phys., Sch. Adv. Sci. & Eng., Waseda Univ., 2Dept. Pure & Appl.
Phys., Grad. Sch. Adv. Sci. & Eng., Waseda Univ., 3Org. Univ. Res. Initiatives, Waseda Univ.)
アガロース微細加工技術を用いた環状心筋細胞ネットワークによる伝導異常モデルの構築
Construction of conduction abnormality model by circular cardiomyocyte network using agarose
microfabrication technology
Koji Emura, Masahito Hayashi, Tomoyuki Kaneko (LaRC, FB, Grad.Sci&Eng, Hosei Univ.)
Width-dependent concave velocity distribution in collective migration is explained by two fluid-likebehavior rules
Hiromichi Hashimoto1, Mitsuru Sentoku2, Syun Koide2, Kento Iida1, Kenji Yasuda1,2,3 (1Dept. Pure &Appl. Phys., Grad. Sch. Adv. Sci. & Eng., Waseda Univ., 2Dept. Phys., Sch. Adv. Sci. & Eng., Waseda Univ.,
3Org. Univ. Res. Initiatives, Waseda Univ.)
高静水圧によるウニ精子細胞内カルシウム濃度への影響
Effects of high hydrostatic pressure on intracellular Ca2+ concentration of sea urchin swimming
live sperm
Hiroshi Imai1,2, Masayoshi Nishiyama3, Yumiko Kaminoe3, Yoshie Harada4, Takahide Kon1,
Shinji Kamimura2 (1Grad. Sch. Sci., Osaka Univ., 2Dept. Biol. Sci., Chuo Univ., 3Dep. Phys., Kindai Univ.,
4IPR, Osaka Univ.)
生細胞における 1 分子イメージングと超解像顕微鏡法を用いた動態と相互作用の定量解析
Quantification of dynamics and kinetics using single-molecule and super-resolution imaging inliving cells
Yuma Ito, Makio Tokunaga (Sch. Life Sci. Tech., Tokyo Tech.)
1 分子イメージングで明らかになった糖鎖によるエクソソーム機能制御
Regulation of exosome function by glycans as revealed by single-molecule imaging
Tatsuki Isogai1, Koichiro M. Hirosawa2, Yasuhiko Kizuka2,3, Yasunari Yokota4, Kenichi G. N. Suzuki2,3(1Grad. Sch. Nat Sci Tech., 2iGCORE, Gifu. Univ., 3CREST, JST, 4Dept. Eng., Gifu Univ.)
アクチンの重合と脱重合の熱測定
Calorimetry of actin polymerization and depolymerization
Shouron Kure, Hideyuki Komatsu (Dept. Biosci. Bioinf., Kyushu Inst. Tech)
線虫 MEC-2 および相互作用チャネル蛋白質の構造・生化学的解析
The structural and biochemical analyses of MEC-2 and its partner channel proteins in C. elegans
Norihiro Takekawa1, Maria Uehori2, Shunji Nakano3, Ikue Mori3, Michio Homma4, Katsumi Imada1(1Dept. of Macromol. Sci., Grad. Sch. of Sci., Osaka Univ., 2Dept. of Chem., Fac. of Sci., Osaka Univ.,
3NSI, Grad. Sch. of Sci., Nagoya Univ., 4Div. of Biol. Sci., Grad. Sch. of Sci., Nagoya Univ.)
ヒト iPS 細胞を用いた原腸形成時の自己組織化運動
Self-organizing movement during gastrulation using human iPS cells
Ryo Kobayashi1, Chihiro Takeuchi2, Kiyoshi Ohnuma3 (1Grad. Sch. Eng., Univ. Nagaoka Tech., 2Eng.,
Univ. Nagaoka Tech., 3Inn., Univ. Nagaoka Tech)
マウス気管の繊毛運動による喘息原因物質キチンの輸送
Observation of ciliary motility of murine trachea and epithelial transport of chitin involved in thedevelopment of asthma
Arata Imaizumi1, Keiju Kawano1, Nobukiyo Tanaka1, Susumu Nakae2, Koji Ikegami3, Tomoko Masaike1(1Dept. Appl. Biol. Sci. Tokyo Univ. Sci., 2Grad. Sch. of Integrated Sci. for Life, Hiroshima Univ., 3Grad.
Sch. of Biomedical & Health Sci., Hiroshima Univ.)
リアルタイムフィードバック制御による機械的刺激に影響を受けた心筋細胞の拍動
Beat sequence of cardiomyocytes affected by to mechanical stimulus with real-time feedback
control
Shota Nozaki, Kazuki Mammoto, Takashi Miyazawa, Ryuta Watanabe, Yuta Moriyama, Ryu Kidokoro,
Toshiyuki Mitsui (Aoyama Gakuin University)– S75 –

20282H

20283H

20284H

20285H

20286H

20287H

20288H

20289H

20290H

20291H

20292H*

心筋梗塞の治療のための in vitro 移植モデルにおけるペースメーカーの入れ替わり
Pacemaker switching of in vitro transplantation model for heart infarction
Toru Nakamura, Chiho Nihei, Masahito Hayashi, Tomoyuki Kaneko (Laboratory for Reconstructive Cell
biology, Department of Frontier Bioscience, Hosei University, Grad. School of Science and Engineering)
圧力がミトコンドリアの機能に及ぼす影響
Effects of pressure on mitochondrial activity
Yoshiki Oie1, Yoshihiro Ohta2 (1Grad. Sch. Sci., Tokyo University of Agriculture and Technology, 2Tokyo
University of Agriculture and Technology)
タウ–微小管とタウ–ヘパリン相互作用の等温滴定熱測定の比較
Comparative analysis between isothermal titration calorimetries of tau–microtubule and tau–herparin interactions
Junta Kashima, Rio Okamoto, Hideyuki Komatsu (Dept. Biosci. Bioinf., Kyushu Inst. Tec)
ミトコンドリア電子伝達系のプロトンポンプ活性の単一細胞検出
Detection of proton pump activities in mitochondrial electron transfer chain in a single cell level
Yoshiki Suganuma, Masato Miura, Hiroko Kashiwagi, Yoshihiro Ohta (Tokyo University of Agriculture
and Technology, Department of Biotechnology and Life Sciences.)
単細胞 FRET とべん毛モーター回転による CheYp 濃度の同時観察による適応系のメカニズム解明
Elucidation of mechanism for adaptation system through the simultaneous observation CheYp bysingle cell FRET and flagellar motor rotation
Takuma Nakagawa, Tatsuya Yamakoshi, Che Yong-Suk, Hajime Fukuoka, Akihiko Ishijima (Grad. Sch.
Frontier Biosci. Osaka Univ.)
Simultaneous observation of chemotactic response and intracellular behavior of chemotaxis
proteins at single E. coli cell
Taro Yuri, Takuma Nakagawa, Keisuke Nishitani, Yong-Suk Che, Yumiko Uchida, Akihiko Ishijima,
Hajime Fukuoka (Grad. Sch. Frontier Biosci., Osaka Univ.)
CheB の細胞内動態とべん毛モーター回転の同時計測
Simultaneous measurement of flagellar motor rotation and Dynamics of CheB localization duringchemotactic response
Keisuke Nishitani1, Tatsuki Hamamoto2, Yong-Suk Che1, Akihiko Ishijima1, Hajime Fukuoka1 (1Grad.
Sch. Frontier Biosci. Osaka Univ., 2OIST. Grad. Univ.)
回転方向に依存したべん毛モーターの回転揺らぎの高時間分解能測定。
High temporal resolution measurement of rotational fluctuation of flagellar motor depending on
rotational direction
Koki Murai, Akihiko Ishijima, Hajime Fukuoka (Grad. Sch. Frontier Biosci. Osaka Univ.)
心筋細胞における拍動間隔の温度依存性
Temperature dependence of beating rate in cardiomyocytes
Kohei Oyama, Masahito Hayashi, Tomoyuki Kaneko (Laboratory for Reconstructive Cell Biology,
Department of Frontier Bioscience, Hosei University, Grad School of Science and Engineering)
走化性タンパク質 CheRCheB の存在と大腸菌スイッチング同調
Requirement for Chemotaxis Protein CheR and CheB for the switching coordination between two
flagellar motors on E. coli cell
Tatsuki Hamamoto2, Yumiko Uchida1, Yong-Suk Che1, Akihiko Ishijima1, Hajime Fukuoka1 (1Grad. Sch.
Frontier Biosci. Osaka Univ, 2OIST Grad. Univ)
レプトスピラ経皮侵入に関わる運動の重要性
Significance of motility for percutaneous invasion of the spirochete Leptospira
Keigo Abe1, Toshiki Kuribayashi1, Kyosuke Takabe2, Shuichi Nakamura1 (1Department of Applied
Physics, Graduate School of Engineering, Tohoku University, 2Faculty of Life and Environmental Sciences,
University of Tsukuba)– S76 –

20293H*

20294H*

20295H

20296H

20297H

蛍光および反射干渉顕微鏡による細胞－基板界面でのがん細胞膜の分子パッキングの評価
Evaluation of molecular packing of cancer cell membrane at cell-substrate interface byfluorescence and interference reflection microscopy
Hayata Noro1, Mai Fujii1, Shodai Togo1, Mami Watanabe1, Masami Suganuma2, Naritaka Kobayashi2,
Ryozo Kawamura1,2, Seiichiro Nakabayashi1,2, Takahisa Matsuzaki2, Hiroshi Yoshikawa1,2 (1Dept. of
Chem., Saitama Univ., 2Div. of Strateg. Res. and Dev., Grad. Sch. of Sci. and Eng., Saitama Univ.)
細胞接着界面の膜分子配列性の評価：がん細胞と正常細胞の比較
Characterization of molecular packing of cell membranes at cell-substrate interface:Comparison
between cancer cells and normal cells
Mai Fujii1, Hayata Noro1, Syodai Togo1, Mami Watanabe1, Masami Suganuma2, Naritaka Kobayashi2,
Ryuzo Kobayashi1,2, Seiichiro Nakabayashi1,2, Takahisa Matsuzaki2, Hiroshi Y. Yoshikawa1,2 (1Grad.
Chem., Univ. Saitama, 2Division of Strategic Research and Development, Grad. Sci. Eng., Univ. Saitama)
人工多細胞型分子ロボットの自動生産に関する研究
Toward Automated Production of Multicellular Molecular Robots
Ryo Shimizu1, Satoshi Murata1, Shin-ichiro Nomura1, Yuki Suzuki4, Ibuki Kawamata1, Gen Hayase3,
Taro Toyota2 (1Murata/Nomura Lab, Univ. Tohoku, 2Toyota Lab, Univ. Tokyo, 3MANA, 4FRIS, Univ.
Tohoku)
繊毛の初期屈曲形成に重要な根元局在型マイナーダイニン
Requirement of minor-type axonemal dyneins localized to the proximal region for the initial bend
formation of cilia
Tomohiro Komatsu, Ayuna Sahara, Yusuke Kondo, Toshiki Yagi (Dept. Life Sci. Prefectural Univ.
Hiroshima)
Formation of actin cortex structure by myosin motor activity
Mitsusuke Tarama, Tatsuo Shibata (RIKEN BDR)
I. 生体膜・人工膜／I. Biological & Artificial membrane

20298I*

20299I*

20300I*

20301I

抗菌ペプチド・マガイニン 2 と脂質膜の相互作用に対する膜電位の効果
Effect of Membrane Potential on Interaction of Antimicrobial Peptide (AMP) Magainin 2 (Mag) with
Single GUVs
Or Rashid Md. Mamun1, Moghal Md. Mizanur1, Billah Md. Masum1, Hasan Moynul1,
Yamazaki Masahito1,2,3 (1Grad. Sch. Sci. Tech., Shizuoka Univ., 2Res. Inst. Ele., Shizuoka Univ., 3Grad.
Sch. Sci., Shizuoka Univ.)
蛍光プローブでラベルされていない細胞透過ペプチド・トランスポータン 10 の巨大リポソーム内腔への侵入の検出
Detection of the Entry of Nonlabeled Cell-Penetrating Peptide (CPP) Transportan 10 (TP10) into
Single Giant Unilamellar Vesicles (GUVs)
Madhabl Lata Shuma1, Md. Mizanur Moghal1, Masahito Yamazaki1,2,3 (1Grad. Sch. Sci. Tech., Shizuoka
Univ., 2Res. Inst. Ele., Shizuoka Univ., 3Grad. Sch. Sci., Shizuoka Univ.)
脂質分子の二分子層膜横断（フリップ・フロップ）に対する浸透圧の効果
The effect of osmotic pressure on the transbilayer movement (flip-flop) of lipid molecules
Samiron Kumar Saha1, Masahito Yamazaki1,2,3 (1Grad. Sch. Sci. Tech., Shizuoka Univ., 2Res. Inst. Ele.,
Shizuoka Univ., 3Grad. Sch. Sci., Shizuoka Univ.)
脂質・コレステロールによって制御される上皮成長因子受容体の膜貫通・膜近傍ドメインの多量体形成機構
Lipid-cholesterol regulation of the oligomerization in transmembrane and juxtamembrane domainsof epidermal growth factor receptor
Ryo Maeda1, Takeshi Sato2, Yasushi Sako1 (1Cellular Informatics Lab., RIKEN, 2Kyoto Pharmaceutical
Univ.)– S77 –

20302I*

20303I*

20304I
20305I

20306I

20307I*

20308I

20309I

20310I

20311I

20312I

抗菌ペプチド・ラクトフェリシン B(4-9)の大腸菌、スフェロプラスト、および巨大リポソームの内腔への侵入に対する膜電位の効果
Effect of Membrane potential on Entry of Antimicrobial Peptide (AMP) LfcinB (4-9) into Single E.
coli Cells, Spheroplasts, and GUVs
Farzana Hossain1, Masahito Yamazaki1,2,3 (1Grad. Sch. Sci. Tech., Shizuoka Univ., 2Res. Inst. Ele.,
Shizuoka Univ., 3Grad. Sch. Sci., Shizuoka Univ.)
アミロイド線維形成とリン脂質二分子膜破壊との関係性の解明
Investigation of relationships between amyloid fibril formation and phospholipid bilayer destruction
Hiroki Takayama1, Kaori Mageshi1, Kenichi Morigaki2, Eri Chatani1 (1Graduate School of Science, Kobe
University, 2Biosignal research center, Kobe University, 3Graduate School of Agricultural Science, Kobe
University)
Regulation of actin dynamics by phosphoinositides
Yosuke Senju (RIIS, Univ. Okayama)
高速 AFM によるハブ毒液由来脂質分解酵素 PLA2 の膜認識機構の解明
Membrane recognition mechanism of phospholipase A2 from habu snake venom revealed byhigh-speed AFM (HS-AFM)
Magoto Kamiya1, Mikihiro Shibata2,3, Naoko Oda-Ueda4, Ayumi Sumino2,3 (1Grad. Sch. Math. & Phys.,
Kanazawa Univ., 2WPI-NanoLSI, Kanazawa Univ., 3InFiniti, Kanazawa Univ., 4Dept. Pharm. Sci., Sojo
Univ.)
2 種類のリン脂質種からなるモデル生体膜の構造に対するコレステロールとラノステロールの影響の比較
Comparative study of the effects of cholesterol and lanosterol on the structure of model
biomombrane formed by two phospholipid species
Akira Matsumoto, Hiroshi Takahashi (Grad. Sch. Sci and Tech., Gunma University)
細胞サイズ閉じ込め中の拡散に対する界面の効果
Effects of membrane interface properties on diffusion in cell-sized confinement
Kanae Harusawa1,2, Chiho Watanabe2, Akira Kitamura3, Masataka Kinjo3, Miho Yanagisawa2 (1Grad.
Sch. Eng., Tokyo Univ. of Agri. and Technol., 2Grad. Sch. Arts and Sci., The Univ. of Tokyo, 3Grad. Sch.
Life Sci., Hokkaido Univ.)
相分離リポソームを用いた膜タンパク質の高濃度再構成
High-density reconstitution of membrane protein into phase-separated liposome
Mizuki Kobayashi1,2, Kei Fujiwara3, Chiho Watanabe2, Miho Yanagisawa2 (1Grad. Sch. Eng., Tokyo Univ.
of Agri. and Tech, 2Grad. Sch. Arts and Sci., The Univ. of Tokyo, 3Sch and Tech.Biosciences andInformatics., Keio Univ)
鞭毛で泳ぐ単細胞緑藻クラミドモナスを用いて巨大リポソームを内側から動かす
Driving a giant liposome from inside by a flagellating unicellular green algae Chlamydomonas
Shunsuke Shiomi1, Masahito Hayashi1, Tomohiro Uemura2, Tomoyuki Kaneko1 (1LaRC, FB, Hosei Univ.,
2FB, Hosei Univ.)
ラベルされていない抗菌ペプチド・PGLa と単一 GUV との相互作用
Interaction of Nonlabeled Antimicrobial Peptide PGLa with Single Giant Unilamellar Vesicles(GUVs)MD Hazrat Ali1, Madhabl Lata Shuma1, Masahito Yamazaki1,2,3 (1Grad. Sch. Sci. Tech., Shizuoka Univ.,
2Res. Inst. Ele., Shizuoka Univ., 3Grad. Sch. Sci., Shizuoka Univ.)
Epigallocatechin gallate induces the burst of giant unilamellar vesicles in the tension-dependent
mannerNaoya Sugita1, Mika Terada1, Yukihiro Tamba1, Masahito Yamazaki2 (1Natl. Inst. Tech., Suzuka Coll.,
2Shizuoka Univ.)
筋小胞体 Ca ポンプの M2 ヘリックス:膜貫通部分のエネルギー共役における役割
Role of transmembrane portion of M2 helix in energy coupling of sarcoplasmic reticulum Ca pump
Takashi Daiho, Kazuo Yamasaki, Satoshi Yasuda, Jun-ichi Kawabe (Asahikawa Med. Univ. Biochem.)– S78 –

20313I*

20314I*

20315I

20316I

20317I

20318I*

20319I

20320I

20321I

20322I

20323I*

20324I

20325I

脂質分子混み合い効果によるバクテリオロドプシン間実行相互作用の解析
Crowding effects induced by lipid molecules on effective interactions between bacteriorhodopsins
Keiju Suda1, Ayumi Suematsu2, Rho Akiyama1 (1Kyushu University, science faculty, department ofchemistry, 2Kyushu sangyo University)
ナノサイズリポソームの脂質膜への融合条件の調査
Examination of fusion condition of nano-sized liposome to lipid membrane
Chika Arisaka, Kouki Kamiya (Grad. Sch. Sci and Tec., Univ. Gunma)
ハイドロゲル固体試料中で見られた紫膜の特異な積層構造の形成機構
Formation Mechanisms of Anomalous Purple Membrane Stacking in Hydrogels
Yasunori Yokoyama1, Riku Kurita1, Shunsuke Yano1, Koshi Takenaka1, Hiroshi Takahashi2,
Masashi Sonoyama2,3,4 (1Grad. Sch. Eng., Nagoya Univ., 2Grad. Sch. Sci. & Tech., Gunma Univ., 3GIAR,
Gunma Univ., 4GUCFW, Gunma Univ.)
ベシクル凝集構造の力学モデル
Mechanical Model of Vesicle AggregatesToshikaze Chiba1, Masayuki Imai1, Primoz Ziherl2,3 (1Grad. Sch. Sci., Tohoku Univ, 2Jozef Stefan Inst,
3Ljubljana Univ)
In vitro selection using cDNA display for liposome binding peptides to generate antibacterial
peptidesTakeru Yoshinobu, Naoto Nemoto (Graduate School of Science & Engineering, Saitama University)
Pattern Formation by Mechanochemical Feedback between Membrane Deformation and theBrusselator Model
Naoki Tamemoto, Hiroshi Noguchi (ISSP, Univ. Tokyo)
ナノサイズリポソーム融合による細胞サイズ GM1 非対称膜リポソームの構築
Construction of cell-sized GM1 asymmetric vesicles using nano-sized vesicle fusion method
Masato Suzuki1, Kouki Kamiya1,2 (1Sci. & Tech., Univ. Gunma, 2Grad. Sci. & Tech., Univ. Gunma)
電位依存性プロトンチャネルの細胞内側からの制御
Intracellular regulation of the voltage-gated proton channel
Akira Kawanabe, Yuichiro Fujiwara (Kagawa Univ.)
Artificial bilayers on hydrogel for channel current recordings
Toru Ide1,2, Minako Hirano2, Daiki Yamamoto1, Mami Asakura3, Yuki Kitamura3 (1Grad Schl Health
Systems Okayama Univ, 2GPI, 3Fac Eng Okayama Univ)
イノシトールリン脂質による KcsA の制御
Functional coupling between phosphoinositides and KcsA studied by lipid-bilayer recording
Takunari Kiya, Akira Kawanabe, Yuichiro Fujiwara (Kagawa Univ.)
自動顕微鏡計測により見出された，定常流れ場における細胞サイズのリポソームへの分子濃縮
Automated direct observation unveiled hydrodynamic accumulation of molecules into cell-sized
liposomes against a concentration gradient
Hironori Sugiyama1, Toshihisa Osaki2,3, Shoji Takeuchi2,4, Taro Toyota1,5 (1Grad. Sch. Arts and Sci., The
University of Tokyo, 2IIS, The University of Tokyo, 3KISTEC, 4Grad. Sch. Info. Sci. Tech., The University ofTokyo, 5UBI, The University of Tokyo)
平面脂質膜の組成の違いによる OmpG の膜への挿入の違いについて
Differences of OmpG into the planar lipid membranes with various compositions
Toshiyuki Tosaka1, Koki Kamiya2 (1Sci. & Tech., Univ. Gunma, 2Grad. Sci. & Tech., Univ. Gunma)
油中水滴エマルションにおけるヒドロキシプロピルセルロースのパターン形成とダイナミクス
Pattern formation and dynamics of hydroxypropyl cellulose in water-in-oil emulsion
Kazunari Yoshida1, Keitaro Horii2, Azusa Saito2, Akito Takashima2, Izumi Nishio2 (1Grad. Sch. Sci. Eng.,
Yamagata Univ., 2Col. Sci. Eng., Aoyama Gakuin Univ.)– S79 –

20326I

20327I

20328I

20329I

20330I*
20331I*

20332I*

20333I

20334I*

20335I

20336I*

20337I

20338I*

Effect of lipid quality on the association of membrane bound proteins with phosphoinositidecontaining membranes
Eiji Yamamoto1, Junko Sasaki2, Takehiko Sasaki2, Mark S. P. Sansom3 (1Department of System Design
Engineering, Keio University, 2Medical Research Institute and Graduate School of Medical and Dental
Sciences, Tokyo Medical and Dental University, 3Department of Biochemistry, University of Oxford)
気液界面における人工肺サーファクタント膜へのコレステロールの影響
Effect of cholesterol on a model lung surfactant monolayer at the air-water interface
Masahiro Hibino1, Saki Izumi2 (1Div. Sustain. Environ. Eng., Muroran Inst. Tech., 2Dept. Appl. Sci.,
Muroran Inst. Tech.)
自動生成される人工多細胞体とその電気的活性について
On multicellular lipid compartments and their electrical activity
Shin-ichiro Nomura (Dep. Robotics, TOHOKU Univ.)
分子シミュレーションによるリポソームにおける膜タンパク質拡散解析
Molecular dynamics simulation of the diffusion of membrane proteins on vesicles
Diego Ugarte, Shoji Takada (Dept. Biol., Sch. Sci., Kyoto Univ., Japan)
Observation Protein-Protein Interactions in α-hemolysin
Misa Yamaji, Ryuji Kawano (Tokyo University of Agriculture and Technology)
Outer membrane phospholipaseA (OmpLA)を用いた細胞モデルの構築
Creation of complex-functional cell model using outer membrane phospholipase A
Seren Ohnishi, Koki Kamiya (Grad. Sci., Univ.Gunma)
α-ヘモリシンナノ空間における β ヘアピンペプチドのイオン電流記録
Ion current recording of a β-hairpin peptide in confined α-hemolysin nanospace
Miyu Fukuda, Misa Yamaji, Ryuji Kawano (Department of biotechnology and life science, Tokyo
University of Agriculture and Technology)
大腸菌が引き起こすリポソームの形態変化パターン解析
Analysis of morphological change patterns of liposomes driven by encapsulated E. coli
Mai Hayakawa, Masahito Hayashi, Tomoyuki Kaneko (LaRC, FB, Grad. Sch. Sci. & Eng., Hosei Univ.)
Construct analysis system between peptide local structure in lipid membrane and membrane
deformation
Kayano Izumi, Ryuji Kawano (Department of Biotechnology and Life science, Tokyo University ofAgriculture and Technology)
サイズ選択性を有する DNA オリガミ人工チャネル
Size-selective molecular transportation by DNA origami channel
Shoji Iwabuchi1, Ibuki Kawamata1,2, Satoshi Murata1, M. Shin-ichiro Nomura1 (1Rob. Eng., Univ. Tohoku,
2Nat. Sci., Fuc. Core Res., Univ. Ochanomizu)
Protein crowder as a modulator of Min wave generation for cell division
Saki Nishikawa, Shunshi Kohyama, Nobuhide Doi, Kei Fujiwara (Faculty of science and technology, Keio
University)
脂質二分子膜に働く光捕捉力の検証
Lateral diffusion in lipid bilayers biased by optical forces
Yuto Ishihara1, Tutsunori Kishimoto1,2, Fuko Kueda3,4, Suguru N. Kudoh2, Kenichi Morigaki3,4,Chie Hosokawa1,5 (1Grad. Sch. Sci., Osaka City Univ., 2Grad. Sch. Sci. Tech., Kwansei Gakuin Univ.,
3Grad. Sch. Agr., Kobe Univ., 4Biosignal., Kobe Univ., 5PhotoBIO-OIL, AIST)
細胞膜の物理的状態の制御に向けた生物活性ナノ材料の設計並びに評価
Design and Evaluation of Bioactive Nanomaterials toward Control of Physical Properties of
Plasma Membrane
Tomohiro Nobeyama1, Hyungjin Kim2, Kazuki Shigyo3, Hirotaka Nakatsuji4, Hiroshi Sugiyama5,
Naoko Kawamura6,7, Hiromune Ando6,7, Tatsuya Murakami1,8,9 (1Grad. Sch. of Eng., Toyama Prefectural
Univ., 2Grad. Sch. of Med., Yamaguchi Univ., 3Grad. Sch. of Integrated Sciences for Life., Hiroshima Univ,
4Grad.Sch. of Eng., Osaka Univ., 5Grad.Sch.of Sci., Kyoto Univ., 6G-CHAIN., Gifu Univ, 7iGCORE.,Tokai
National Higher Education and Research System, 8Fac.of.Eng., Toyama Prefectural Univ., 9KUIAS.,Kyoto
Univ)– S80 –

J. 化学受容・神経／J. Chemoreception,Neuroscience & Sensory systems
20339J*

20340J*

20341J

20342J*

線虫の低温耐性を制御する新規の GPCR 型温度センサー分子
Novel GPCR-type temperature receptor in cold tolerance of C. elegans
Kohei Ohnishi, Toru Miura, Tomoyo Ujisawa, Akane Ohta, Atsushi Kuhara (Inst. for Integrative
Neurobiology, Konan Univ., Japan)
ヒトムスカリン性アセチルコリン受容体 (M2) のリガンド認識機構の理解に向けた赤外分光研究
Infrared spectroscopic study for elucidating ligand recognition mechanism of human M2
muscarinic acetylcholine receptor
Kohei Suzuki1, Kota Katayama1, Ryoji Suno2, Yuji Sumii1, Norio Shibata1, Hideki Kandori1 (1Grad. Sch.
Eng., Nagoya Inst. Tech, 2Kansai Medical University. Medical.)
Clostridium 属細菌の走化性アッセイ法の確立
Establishment of Methods for Chemotaxis Assays of Clostridium spp.
So-ichiro Nishiyama, Susumu Oogoshi, Hiroshi Urakami (Fac. App. Life Sci., Niigata Univ. Pharm. App.
Life Sci.)
非平衡流動場における脂質膜へのアミロイド β 凝集の単分子観察
Single Molecule Observation of Amyloid β Aggregation to Lipid Membrane under Non-equilibrium
Fluidic Condition
Akane Iida1, Hideki Nabika2 (1Grad. Sch. of Sci. and Eng., Yamagata Univ., 2Fac. of Sci., Yamagata
Univ.)
K. 神経回路・脳の情報処理／K. Neuronal circuit & Information processing

20343K

20344K

20345K

20346K

20347K

20348K

線虫 C. elegans を用いた異なる感覚情報の統合に関わる神経回路モデル
The model of neural circuit integrating different sensory information in C. elegans
Misaki Okahata1, Aguan D. Wei2, Akane Ohta1, Atsushi Kuhata1,3 (1Inst. for Integrative Neurobio., Konan
Univ., 2SEA Children’s Research Inst., 3AMED-PRIME)
海馬で合成される男性・女性ホルモンやストレスホルモンによる記憶シナプスの早い non-genomic
な制御
Rapid non-genomic modulation of synapses by hippocampus-synthesized androgen, estrogenand stress steroid
Suguru Kawato1,2, Mika Soma1,2, Mari Ikeda-Ogiue1,2, Minoru Saito2 (1Dep. Urology, Grad Sch Medicine,
Juntendo Univ., 2Dep. Life sciences, College Humanities and Sciences, Nihon Univ.)
線虫において脂肪酸代謝経路の β 酸化で働く HADH が低温馴化を制御する
HACD-1 that is beta-oxidation of fatty acid metabolism regulates cold acclimation in intestine andsensory neurons in C. elegans
Akihisa Fukumoto1, Atushi Kuhara1, Akane Ohta1, Misaki Okahata1, Youhei Minakuti2, Atushi Toyoda2(1Inst. for Integrative Neurobio., Konan Univ., 2NIG, Japan)
細胞間の活動同期性に基づく神経クラスタの統計的推測
Statistical inference of neuronal ensembles based on synchronous activity among neurons
Shun Kimura, Koujin Takeda, Yuishi Iwasaki (Grad. Sch. Sci. Eng., Univ. Ibaraki)
Integrated signaling from thermosensoryneurons at a tail interneuron regulates cold acclimation
Haruka Motomura, Satoko Fujii, Makoto Ioroi, Atsushi Kuhara, Akane Ohta (Institute for integrative
Neurobiology, Konan Univ.)
内因性カンナビノイドによる小脳 GABA シナプス伝達のシナプスタイプ別制御
Endocannabinoids regulate cerebellar GABAergic transmission in a synapse type-dependent
mannerMoritoshi Hirono1,2, Yuchio Yanagawa3 (1Dep. Physiol., Wakayama Med. Univ. Sch. Med., 2Grad. Sch.
Brain Sci., Doshisha Univ., 3Dep. Genetic and Behav. Neurosci., Gunma Univ. Grad. Sch. Med.)– S81 –

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A method to differentiate neurite non-invasively with needle agarose microfabrication technology
Yuhei Tanaka, Haruki Watanabe, Kenji Shimoda, Kenji Yasuda (Dept. Pure & Appl. Phys., Grad. Sch.
Adv. Sci. & Eng., Waseda Univ.)
微小多電極解析のための神経細胞の 1 細胞レベル長期培養環境の最適化
Optimization of the long-term cultural environment of isolated single neurons for micromultielectrode analysis
Kenji Shimoda, Yuhei Tanaka, Haruki Watanabe, Kenji Yasuda (Dept. Pure & Appl. Phys., Grad. Sch.
Adv. Sci. & Eng., Waseda Univ.)
1 神経突起の伸長を長期間観察さるための改良された µm 分解能のアガロース微細加工技術の評価
Evaluation of an improved μm resolution agarose microfabrication technology for long-term
individual neurite elongation observation
Haruki Watanabe1, Yuhei Tanaka1, Kenji Shimoda1, Kenji Yasuda1 (1Dept. Pure & Appl. Phys., Grad.
Sch. Adv. Sci. & Eng., Waseda Univ., 2Dept. Pure & Appl. Phys., Grad. Sch. Adv. Sci. & Eng., Waseda
Univ., 3Dept. Pure & Appl. Phys., Grad. Sch. Adv. Sci. & Eng., Waseda Univ., 4Dept. Pure & Appl. Phys.,Grad. Sch. Adv. Sci. & Eng., Waseda Univ.)
マウス海馬の長期増強を膜電位感受色素によるイメージングで観察する
Imaging analysis of the long-term potentiation of the mouse hippocampal activity
Yoko Tominaga, Makiko Taketoshi, Takashi Tominaga (Inst Neurosci Tokushima Bunri Univ.)
プリオンタンパク質ノックアウトマウスにおける小脳長期抑圧障害
Impairment of cerebellar long-term depression in prion protein-deficient mice ectopically
expressing PrPLP/Dpl
Yasushi Kishimoto1, Moritoshi Hirono2, Ryuichiro Atarashi3, Suehiro Sakaguchi4, Tohru Yoshioka5,
Shigeru Katamine6, Yutaka Kirino1 (1Kagawa Sch. Pharm. Sci., Tokushima Bunri Univ., 2Dep. Physiol.,Wakayama Med. Univ. Sch. Med., 3Fac. Med., Univ. of Miyazaki, 4KOSOKEN, Tokushima Univ.,
5Kaohsiung Medical Univ., 6CICORN, Nagasaki Univ.)
ミミズ短期記憶におけるセロトニンの関与
Involvement of serotonin in short-term memory of earthworms
Yoshiichiro Kitamura, Toshiaki Nakahara, Hikaru Takahashi (Dept Math Sci Phys, Col Sci Eng, KGU)
L. 行動／L. Behavior

20355L20356L*20357L20358L

蟻はピンクノイズで探索する
Ants run on a treadmill with the pink noise
Tomoko Sakiyama1, Naohisa Nagaya2, Ryusuke Fujisawa3 (1Soka University, 2Kyoto Sangyo University,
3Kyushu Institute of Technology)
隠れマルコフモデルと逆強化学習法による生物複数戦略の同定
Identification of multiple strategies by inverse reinforcement learning with hidden-Markov model
Kohei Morimoto1,2, Muneki Ikeda3,4, Yuki Tsukada3, Nakano Shunji3, Ikue Mori3,4, Naoki Honda2,5,6(1Undergrad. Info. and Math., Kyoto Univ., 2Grad. Bio., Kyoto Univ., 3Grad. Sci., Nagoya Univ., 4CBS.,
Riken, 5Research Center for Dynamic Living Systems, Kyoto Univ., 6ExCELLS, NINS.)
睡眠の剥奪はショウジョウバエによる食物臭の嗜好性を変化させる
Sleep deprivation alters food odor preference in Drosophila
Fuminori Tanizawa1,2, Hiroyuki Takemoto3 (1Kaisei Senior High School, 2Future Scientists’ School,
Shizuoka University, 3Research Institute of Green Science and Technology, Shizuoka University)
壁近くのゾンビ化した単鞭毛クラミドモナスの遊泳
Swimming of zombifield monoflagellated Chlamydomonas near wall
Ken Nagai (JAIST)– S82 –

20359L*

報酬と好奇心によって駆動される行動を表現する意思決定モデル
A decision-making model for reward and curiosity-driven behavior
Yuki Konaka1,2, Naoki Honda1,2 (1Graduate School of Biostudies, Kyoto university., 2Theoretical Biology
Research Group, Exploratory Research Center on Life and Living Systems (ExCELLS), National Institutesof Natural Sciences.)
M. 光生物:視覚・光受容・光合成・光制御／M. Photobiology

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20364M

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20368M

マウス桿体視細胞においてロドプシンを介するが光オフで生じるプロテインキナーゼ A の活性化
Rhodopsin-mediated Light-off-induced Protein Kinase A Activation in Mouse Rod Photoreceptor
Cells
Shinya Sato1, Takahiro Yamashita2, Michyuki Matsuda1,3 (1Grad. Sch. Biostud., Univ. Kyoto, 2Grad. Sch.
Sci., Univ. Kyoto, 3Grad. Sch. Med., Univ. Kyoto)
光合成酸素発生系における g=5 S2 状態の分子構造
Molecular Structure of the S2 State with a g=5 Signal in the Oxygen Evolving Complex of
Photosystem II
Hiroyuki Mino, Shota Taguchi, Takumi Noguchi (Grad. Sch. Sci., Nagoya Uni.)
QM/MM-MD による光回復酵素-紫外線損傷 DNA 複合体の逐次修復反応中における反応中間体の観測に成功
QM/MM-MD approach for photolyase-UV-damaged DNA complex achieved that observe anintermediate in the successive DNA repair reactions
Ryuma Sato1, Hiroshi Watanabe2,3, Junpei Yamamoto4, Makoto Taiji1 (1RIKEN, 2Keio univ, KQCC,
3PRESTO JST, 4Osaka univ)
光化学系Ⅱにおける D1-Asp170 の His 変異体の新規なアミノ酸変換
Novel amino acid conversion of a His mutant of D1-Asp170 in photosystem II
Yuichiro Shimada1, Tomomi Kitajima-Ihara1, Ryo Nagao1,2, Takumi Noguchi1 (1Grad. Sch. Sci., Nagoya
Univ., 2Res. Inst. Interdiscip. Sci., Okayama Univ.)
Clarification of proton transfer pathways in water photolysis in photosystem II
Ayane Sugiyama, Yuichiro Shimada, Takumi Noguchi (Division of Material Science, Graduate School of
Science, Nagoya University, Furo-cho, Chikusa-ku, Nagoya 464-8602, Japan)
光化学系Ⅱの第二キノン電子授与体 QB の反応における D1-His252 の役割
Role of D1-His252 in the reaction of the secondary quinone electron accepter QB in photosystem
II
Tomoyuki Kobayashi1, Yuichiro Shimada1, Ryo Nagao2, Takumi Noguchi1 (1Grad. Sch. Sci, Nagoya
Univ., 2Res. Inst. Interdiscip. Sci., Okayama Univ.)
光化学系Ⅱにおけるキノン電子受容体 QA・QB 間の電子移動の時間分解赤外分光検出
Time-resolved infrared detection of electron transfer between quinone electron acceptors QA andQB in photosystem II
Honami Ito, Yuki Kato, Takumi Noguchi (Grad. Sch. Sci, Nagoya Univ.)
Mutational analysis of the mechanism of an absorption red shift in a marine bacterial Cl--pumping
rhodopsin
Takashi Nagata1,2, Masayuki Karasuyama2,3, Ichiro Takeuchi3,4,5, Yu Nakajima6, Susumu Yoshizawa7,
Keiichi Inoue1,4 (1Inst. Solid State Phys., Univ. Tokyo, 2PRESTO, JST, 3Dept. Computer Sci., Nagoya Inst.
Tech., 4RIKEN Center for Advanced Intelligence Project, 5OptoBioTechnology Research Center, Nagoya
Inst. Tech., 6Bioproduction Res. Inst., Nat. Inst. Adv. Indust. Sci. Tech., 7Atmosphere and Ocean Res. Inst.,
Univ. Tokyo)
FTIR spectroelectrochemical study on the mechanism of the pH dependence of the redox
potential of the non-heme iron in photosystem II
Yuki Kato, Hiroki Watanabe, Takumi Noguchi (Grad. Sch. Sci., Nagoya Univ.)– S83 –

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20374M*

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20380M

Spectroscopic properties and energy transfer dynamics of two different forms of acpPC from
dinoflagellate Symbiodinium
Hayata Yamamoto1, Keisuke Kawakami2, Hiroko Uchida3, Akio Murakami3, Nobuo Kamiya4,
Daisuke Kosumi5 (1Dept. of Sci. and Tech., Kumamoto Univ., 2RIKEN, 3Research Center of Island Seas,
Kobe Univ., 4ReCAP, Osaka City Univ., 5IINA, Kumamoto Univ.)
Energy transfers in PSI of cyanobacterium, red alga, and dinoflagellate
Hiroki Serikawa1, Hayata Yamamoto1, Keisuke Kawakami2, Hiroko Uchida3, Akio Murakami3,
Kimiko Nagayoshi4, Toshinari Kuroki4, Susumu Takio5, Nobuo Kamiya6, Daisuke Kosumi7 (1Dept. of Sci.
and Tech., Kumamoto Univ., 2RIKEN, 3Research Center of Island Seas, Kobe Univ., 4Daiichi Seimou Co.,
Ldt., 5CWMD, Kumamoto Univ., 6ReCAP, Osaka City Univ., 7IINa, Kumamoto Univ.)
新しいタイプの光サイクル型動物オプシンの創製
Construction of a novel type of photocycle animal opsin
Kazumi Sakai1, Yoshinori Shichida2, Yasushi Imamoto1, Takahiro Yamashita1 (1Grad. Sch. Sci., Univ.
Kyoto, 2Res. Org. for Sci. and Tech., Univ. Ritsumeikan)
AUREO1-LOV ドメインの光誘起構造変化
Light-induced conformational switching of the LOV domain in aureochrome-1
Itsuki Kobayashi, Hiroto Nakajima, Osamu Hisatomi (Grad. Sch. Sci., Osaka Univ.)
演題取り消し低温赤外分光測定による(6-4)光回復酵素の修復メカニズム解明
Elucidation of the repair mechanism of (6-4) photolyase by low-temperature FTIR spectroscopy
Katsuya Maeda1, Mai Kumagai1, Daichi Yamada2, Yuma Terai3, Junpei Yamamoto3, Hideki Kandori1(1Nagoya Inst. Tech, 2Univ. Hyogo., 3Osaka Univ.)
カチオンチャネルロドプシン Ts_Rh3 における C 末端領域の重要性
Importance of the C-terminal region in cation channel rhodopsin Ts_Rh3
Rintaro Tashiro1, Kumari Sushmita2, Suneel Kateriya2, Hideki Kandori1, Satoshi Tsunoda1,3 (1Nagoya
Inst. Tech., 2Jawaharlal Nehru Univ., 3JST PRESTO)
高速 AFM によるロドプシンクラスター上トランスデューシン動的過程の観察
Dynamic process of G protein transducin on rhodopsin cluster observed by high-speed AFM
Kazuhiko Hoshikaya1, Hayato Yamashita1, Fumio Hayashi2, Kenichi Morigaki3,4, Masashi Fujii5,6,
Akinori Awazu5,6, Masayuki Abe1 (1Graduate School of Engineering Science, Osaka University, 2Graduate
School of Science, Kobe University, 3Biosignal research center, Kobe University, 4Graduate School of
Agricultural Science, Kobe University, 5Graduate School of Science, Hiroshima University, 6Graduate
School of Integrated Sciences for Life, Hiroshima University)
Biophysical characterization of different members of TAT rhodopsins: a new group of microbial
rhodopsins
Kentaro Mannen1, Takashi Nagata1,2, Oded Béjà3, Keiichi Inoue1 (1Inst. Solid State Phys., Univ. Tokyo,
2PRESTO, JST, 3Biol., Israel Inst. Tech.)Actinotalea fermentans におけるヘリオロドプシンの発現
Expression of Heliorhodopsin in Actinotalea fermentans
Rei Abe-Yoshizumi, Ai Muto, Hideki Kandori (Nagoya Inst. Tech.)
絶対嫌気性緑色硫黄光合成細菌における Rieske/cytb 複合体と c 型シトクロム間の相互作用解析
Studies on interaction between Rieske/cytb complex and c-type cytochromes in strictly anaerobic
photosynthetic green sulfur bacteria
Hiraku Kishimoto1, Takahiro Nagaoka1, Chihiro Azai2, Risa Mutoh3, Hideaki Tanaka4, Yohei Miyanoiri4,
Genji Kurisu4, Hirozo Oh-oka1 (1Grad. Sch. Sci., Osaka Univ., 2Col. Life Sci., Ritsumeikan Univ., 3Fac.
Sci., Fukuoka Univ., 4Inst. Protein Res., Osaka Univ.)
脊椎動物の非視覚オプシン Opn5 の多様化の起源の探索
Origin of diversification of vertebrate non-visual opsin Opn5
Takahiro Yamashita1, Kengo Fujii1, Kazumi Sakai1, Yasushi Imamoto1, Hideyo Ohuchi2,
Yoshinori Shichida3 (1Grad. Sch. of Sci., Kyoto Univ., 2Grad. Sch. of Med., Dent. and Pharm. Sci.,
Okayama Univ., 3Ritsumeikan Univ.)– S84 –

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20384M*

20385M*

20386M

20387M

20388M*

20389M*

20390M*

20391M

アニオンチャネルロドプシン吸収波長制御機構の解明
Mechanism of absorption wavelength shifts in anion channelrhodopsin mutants
Masaki Tsujimura1, Tomoyasu Noji1,2, Keiichi Kojima3, Yuki Sudo3, Hiroshi Ishikita1,2 (1Grad. Sch. Eng.,
Univ. Tokyo, 2RCAST., Univ. Tokyo, 3Grad. Sch. Med. Dent.& Pharm., Okayama Univ.)
AUREO1-LOV の光誘起構造変化に関与する水素結合
Hydrogen bonds involved in the light-induced conformational switching of AUREO1-LOV
Yumiko Adachi, Hiroto Nakajima, Osamu Hisatomi (Graduate School of Science, Osaka University)
新たに同定した水素結合ネットワークによる植物由来(6-4)光回復酵素の補因子 FAD の光依存的還元反応の制御A newly identified hydrogen-bonding network modulates photoreduction of the flavin cofactor inplant (6-4) photolyase
Yuhei Hosokawa1, Ryuma Sato2, Martin Saft3, Pavel Muller4, Klaus Brettel4, Lars-Oliver Essen3,
Shigenori Iwai1, Junpei Yamamoto1 (1Grad. Sch. Eng. Sci., Osaka Univ., 2Riken, 3Dept. Chem., Philipps
Univ., 4I2BC, CEA, CNRS)
分光学的手法による霊長類青感受性視物質の光反応構造解析
Photochemical dynamics of a primate blue-sensitive pigment by spectroscopic study
Shunpei Hanai1, Kota Katayama1, Takuma Sasaki1, Hiroo Imai2, Hideki Kandori1 (1Grad. Sch. Eng.,
Nagoya Inst. Tech, 2Prim. Res. Inst. Kyoto Univ.)
Rhodococcus 属細菌が有するヘリオロドプシンの物性および生理機能の探索
Study on physiological functions and physical properties of heliorhodopsin possessed by
Rhodococcus bacteria
Ai Muto, Rei Abe-Yoshizumi, Hideki Kandori (Nagoya Inst. Tech.)
光応答転写因子 Photozipper における二量体形成過程の高速 AFM 観察
High-speed AFM observation on dimer formation of a light-sensing transcription factor,
Photozipper
Akihiro Tsuji1, Kento Nomura1, Hayato Yamashita1, Osamu Hisatomi2, Masayuki Abe1 (1Grad. Sch. ofEng. Sci., Osaka Univ., 2Grad. Sch. of Sci., Osaka Univ.)
光による植物細胞の膜電位制御系の開発
Development of an light regulatory system of membrane potential in plant cell
Masae Konno1,2, Hiromu Yawo1, Hideki Kandori3,4, Keiichi Inoue1 (1ISSP, Univ. Tokyo, 2JST, PRESTO,
3Life Sci. Appl. Chem., Grad. Sch. Eng., NIT, 4OBTRC, NIT)
ビブリオ属のブループロテオロドプシンが示す異常な pH 依存的吸収変化のメカニズム
Mechanism of unusual pH-dependent color change in blue-proteorhodopsin from Vibrio califitulae
Mizuki Sumikawa (Nagoya Inst. Tech)
新規ロドプシンフォスホジエステラーゼ（Rh-PDE）8 種の分子特性
Molecular properties of eight novel rhodopsin phosphodiesterases (Rh-PDEs)
Masahiro Sugiura1, Satoshi Tsunoda1, Masahiko Hibi2, Hideki Kandori1 (1Nagoya Institute of Technology,
2Graduate School of Science, Nagoya University)
内外の配向でのセンサリーロドプシン II の表面増強赤外分光法
Surface-enhanced infrared spectroscopy on sensory rhodopsin 2 tethered with the inside oroutside facing orientation
Jingyi Tang1, Insyeerah Binti Muhammad Jauhari1, Yuji Furutani1,2 (1Grad. Sch. Eng., Nagoya Inst. Tech.,
2OptoBioTech. Research Center, Nagoya Inst. Tech.)
電子励起状態における、フィコシアノビリンの構造変化に関する理論的研究
Exploring the structural changes of phycocyanobilin in the excited states
Kenji Mishima1, Mitsuo Shoji1,2, Yasufumi Umena3, Yasuteru Shigeta1 (1CCS. Univ. Tsukuba, 2JSTPRESTO, 3Jichi Medical University)– S85 –

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20394M

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20397M*

20398M

20399M

20400M

20401M

対称 I 型ヘリバクテリア反応中心光捕集過程の理論解析と光化学系 I との比較
Theoretical analysis of light harvesting mechanism of homodimeric type-I Heliobacterial reaction
center: comparison to PSI
Akihiro Kimura1, Hirotaka Kitoh2,3, Yasuteru Shigeta3, Shigeru Itoh1 (1Department of Physics, Graduate
School of Science, Nagoya University, 2JST, PRESTO, 3Center for Computational Sciences, University ofTsukuba)
錐体・桿体視細胞の外節における脂質環境の解析
Analysis of the lipid environment in outer segment membranes of rod and cone photoreceptor cells
Shuji Tachibanaki1, Keiji Seno2, Tateki Matsui1, Masahiro Ueda1 (1Grad. Sch. of Frontier Biosci., Osaka
Univ., 2Facultiy of Med., Hamamatsu Univ. Sch. of Med.)
固体 NMR による内向きプロトンポンプロドプシン Schizorhodopsin のレチノール発色団の構造解析
Structure of retinal chromophore in Schizorhodopsin as studied by solid-state NMR
Seiya Tajima1, Hideki Kandori2, Keiichi Inoue3, Izuru Kawamura1 (1Grad. Sch. Eng. Sci, Yokohama Nat.
Uni., 2Nagoya Inst. Tech., 3Inst. Solid. State. Phys., Univ. Tokyo)
共役二重結合系を延長したレチナールアナログによる赤色感受性チャネルロドプシンの更なる長波長シフト
Red-Shift of Red-Activatable Channelrhodopsin Using One-Double-Bond-Inserted Retinal
Analogs
Yasushi Imamoto1, Yi-Chung Shen1, Toshikazu Sasaki1, Takahiro Yamashita1, Takashi Okitsu2,
Yumiko Yamano2, Akimori Wada2, Yoshinori Shichida3 (1Kyoto Univ., 2Kobe Pharm. Univ., 3Ritsumeikan
Univ.)
紅色光合成細菌の LH2 タンパク質の色素改変：色素のサイトエネルギーとタンパク質内励起エネ
ルギー移動への影響
Pigment modification in LH2 proteins from purple photosynthetic bacteria: effects on pigment siteenergy and intracomplex energy transfer
Yoshitaka Saga1, Yuji Otsuka1, Madoka Yamashita1, Shiori Nakagawa1, Yuto Masaoka2, Tsubasa Hidaka2,
Yutaka Nagasawa2 (1Fac. Sci. Eng., Kindai Univ., 2Grad. Sch. Life Sci., Ritsumeikan Univ.)
Aureochrome-1 における LOV コアから活性ドメインへの情報伝達機構
Signal transduction from LOV core to effector domain in Aureochrome-1
Hiroto Nakajima, Itsuki Kobayashi, Osamu Hisatomi (Grad. Sci. Sci., Univ. Osaka)
天然アニオンシャネルロドプシン GtACR1 の分子機構に関する理論的研究
Theoretical study on molecular mechanics of natural anion channel rhodopsin GtACR1
Takafumi Shikakura, Cheng Cheng, Shigehiko Hayashi (Kyoto Univ. Graduate School of Science)
Theoretical study of electron transport between cytochrome f and plastocyanin by using a coarsegrained simulation
Kazutomo Kawaguchi, Hidemi Nagao (Inst. Sci. Eng., Kanazawa Univ.)
緑色硫黄細菌のルブレドキシン-酸素酸化還元酵素への電子供与系
Electron transfer path to the rubredoxin-oxygen oxidoreductase in green sulfur bacteria
Wanwipa Ittarat2,4, Takeshi Sato3, Masaharu Kitashima2, Hidehiro Sakurai2,3, Kazuhito Inoue2,3,
Daisuke Seo1 (1Grad Sch Nat Sci&Tec, Kanazawa Univ, 2Dep Biol, Fac Sci, Kanagawa Univ, 3Res Ins Int
Sci, Fac Sci, Kanagawa Univ, 4BIOTEC, NSTDA, Thailand)
Heliobacterium modesticaldum 由来反応中心における励起エネルギー移動および初期電荷分離に関する研究
Studies on excitation energy transfer and primary charge separation in the reaction center
complex from Heliobacterium modesticaldum
Risa Kojima1, Hayata Yamamoto2, Chihiro Azai3, Chiasa Uragami4, Hideki Hashimoto4,
Daisuke Kosumi5, Hirozo Oh-oka1 (1Grad. Sch. Sci., Osaka Univ., 2Grad. Sch. Sci & Tech., Kumamoto
Univ., 3Coll. Life Sci., Ritsumeikan Univ., 4Fac. Sci & Tech., Kwansei Gakuin Univ., 5IINA, Kumamoto
Univ.)– S86 –

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光吸収計算によって現れた C-フィコシアニンの 6 量体構造の機能的な意味
Functional meaning of hexamer structure of C-phycocyanin revealed by calculation of absorption
wavelength
Hiroto Kikuchi (Dept. of Phys. Nippon Med. Sch.)
Connecting the spectral properties to the structure of photosystem I containing Chlorophyll-f
Rin Taniguchi1, Yutaka Shibata1, Toshiyuki Shinoda2, Tatsuya Tomo2, Shen Ye1 (1Tohoku Univ., Grad.
Sch. Sci., 2Tokyo Univ. Sci., Fac. Sci.)
海洋性藻類 Guillardia theta における微生物ロドプシンの遺伝子発現解析
Gene expression analysis of microbial rhodopsins from marine algae Guillardia theta
Yumeka Yamauchi1, Masae Konno1,2, Keiichi Inoue1,2, Hideki Kandori1,3 (1Life Sci. & Appl. Chem.,
Nagoya Inst. Tech., 2ISSP, Univ. Tokyo, 3OBTRC, Nagoya Inst. Tech.)
Theoretical study on molecular mechanism of a light-driven ion transport of Halorhodopsin
Ryo Oyama, Taisuke Hasegawa, Shigehiko Hayashi (Grad. Sch. Sci., Kyoto Univ.)
Disruption of water-mediated H-bond network in rhodopsin mutations cause night blindness
Kota Katayama1, Yuri Takeyama1, Akiko Enomoto1, Hiroo Imai2, Hideki Kandori1 (1Grad.Sch.Eng.,
Nagoya Inst. Tech, 2Primate Res. Inst. Kyoto Univ)
クロロフィル f をもつ光化学系 I 複合体の構造
Structural of photosystem I complex with chlorophyll f
Toshiyuki Shinoda1, Koji Kato2, Ryo Nagao2, Seiji Akimoto3, Jian-Ren Shen2, Fusamichi Akita2,4,
Naoyuki Miyazaki5,6, Tatsuya Tomo1 (1Fac. Sci., Tokyo Univ. Sci., 2RIIS., Okayama Univ., 3Grad. Sch. Sci.,
Kobe Univ., 4PRESTO, JST, 5IPR., Osaka Univ., 6TARA., Tsukuba Univ.)
In situ visualization of reversible state transition in live Chlamydomonas cells by noninvasive
excitation spectral microscopy
Xianjun Zhang1, Yuki Fujita1, Ryutaro Tokutsu2, Jun Minagawa2, Shen Ye1, Yutaka Shibata1 (1Tohoku
Univ., Grad. Sch. Sci., 2NIBB, Div. Environ. Photobiol.)Anion binding to mutants of the Schiff base counterion in heliorhodopsin
Anion binding to mutants of the Schiff base counterion in heliorhodopsin
Manish Singh1, Kota Katayama1, Oded Beja2, Hideki Kandori1 (1Nagoya Inst. Tech, 2Israel Inst. Tech)
光化学系 I 反応中心の電子移動におけるクロロフィルエピマー化の影響
Effect of chlorophyll epimerization on the electron transfer in photosystem I reaction center
Koji Mitsuhashi1, Keisuke Saito1,2, Hiroshi Ishikita1,2 (1Grad. Sch. Eng., Univ. Tokyo, 2RCAST, Univ.
Tokyo)
光化学系 II 水分解触媒部位の交換カップリングの起源
Origin of exchange couplings of the Mn4CaO5 cluster in photosystem II
Shunya Nishio1, Keisuke Saito1,2, Hiroshi Ishikita1,2 (1Fac. Eng., Univ. Tokyo, 2RCAST., Univ. Tokyo)
Simultaneous Mapping of Fluorescence Spectra and Lifetimes of Chlorophylls Revealed
Accumulation of Quenched LHCII
Yuki Fujita, Xianjun Zhang, Touru Kondou, Yutaka Shibata (Organic Physical Chemistry Lab., Tohoku
Univ.)
アゾベンゼン挿入 DNA と T7RNA ポリメラーゼの光転写制御ダイナミクス
Dynamics of photo-regulated transcription reaction of T7 RNA polymerase and azobenzenetethered DNA
Gennosuke Takekawa (Grad. Sch. Sci., Kyoto Univ.)
青色光センサータンパク質 VVD の光反応ダイナミクス
Photoreaction dynamics of blue light sensor protein VVD
Takafumi Nakayama, Andrea Mussini, Yusuke Nakasone, Masahide Terajima (Grad. Sch. Sci., Univ.
Kyoto)The gate-keeper role of a highly conserved helix-3 tryptophan for ion transport of thechannelrhodopsin chimera, C1C2/ChRWR
Yujiro Nagasaka1, Shoko Hososhima2, Keiichi Inoue1, Hideki Kandori2,3, Hiromu Yawo1 (1ISSP., Univ.
Tokyo, 2Grad. Sch. Eng., Nagoya Inst. of Tech, 3Optobio., Nagoya Inst. of Tech)– S87 –

O. 生命の起源・進化／O. Origin of life & Evolution
20416O
20417O

20418O*

20419O*

20420O

20421O
20422O*

20423O
20424O*

20425O

20426O*

20427O*

20428O*

演題取り消し天然の原核生物由来カルシウムチャネルにおけるイオン透過選択性の進化とその決定残基の同定
The selectivity determinant and evolution of a native prokaryotic voltage-dependent calcium
channelKatsumasa Irie1, Takushi Shimomura1,3, Yoshiki Yonekawa2, Hitoshi Nagura1, Michihiro Tateyama3,
Yoshinori Fujiyoshi4 (1CeSPI, Nagoya univ., 2Grad. Pharm. Med. Sci., Nagoya univ., 3Div. Biophys.
Neurobio., NIPS, 4CeSPL,TMDU)
Effects of Oligopeptides on Growth of Primitive Vesicles
Akiko Baba1, Kazuki Yokoyama1, Ulf Olsson2, Masayuki Imai1 (1Department of Physics, Faculty of
Science, Tohoku University, 2Department of Chemistry, Faculty of Science, Lund University)
ベシクル表面上での情報分子成長
Growth of Information Molecules on Vesicle Surface
Yuto Hachiya1, Hikaru Hatori1, Syoichi Toyabe2, Steen Rasmussen3, Masayuki Imai1 (1Phys, Tohoku
Univ., 2Appl. Phys., Grad. Sch. Eng., Tohoku Univ., 3Phys, Chem Pharm, Univ. Southern Denmark)
膜のないドロップレット内での RNA ゲノムの自己複製
Translation-coupled RNA replication in membrane-free droplets
Ryo Mizuuchi1,2, Norikazu Ichihashi1 (1Komaba Institute for Science, Univ. Tokyo, 2JST PRESTO)
Study on evolutionary fluctuation-response relationship in multicellular development
Chikara Furusawa1,2 (1BDR, RIKEN, 2UBI, Graduate School of Science, The University of Tokyo)
膜面上の高分子合成と連携した持続的なベシクルの自己生産
Sustainable Reproduction of Vesicles coupled with a Surface-Confined Template Polymerization
Minoru Kurisu1, Harutaka Aoki1, Takehiro Jimbo1, Yuka Sakuma1, Sandra Luginbuhl2, Peter Walde2,
Masayuki Imai1 (1Dept. of Phys., Tohoku Univ., 2Dept. of Mater., ETH)
How combination of DNA recombination and translation error allows efficient evolution?
Kenta Mitsutomi, Daisuke Kiga (Waseda Univ, Dept Electrical Eng and Biosci)
進化実験による最も単純な等温条件下 DNA 複製機構の探索
Minimization of Elements for Isothermal DNA Replication by an Evolutionary Approach
Hiroki Okauchi1, Yoshihiro Sakatani2, Kensuke Otuka2, Norikazu Ichihashi1,2 (1Dept. Life Sci., Univ.
Tokyo, 2Dept. Bioinfo. Eng., Univ. Osaka)
ホストパラサイト相互作用による表現型可塑性の進化
Evolution of Phenotypic Plasticity in Host-Parasite Interactions
Naoto Nishiura, Kunihiko Kaneko (The University of Tokyo Graduate School of Arts and Sciences)
高分子混雑環境下でのミクロ相分離が創成する細胞様構造体
Emergence of cell-like structure through micro phase separation in a crowding macromolecularsolution
Fumika Fujita1, Hiroki Sakuta1, Kanta Tsumoto2, Takahiro Kenmotsu1, Kenichi Yoshikawa1 (1Facul. Life
Med. Sci., Doshisha Univ., 2Facul. Eng., Mie Univ.)
人工膜小胞内リン脂質合成による自律的細胞分裂機構の構築
Development of a self-reproducing vesicular system driven by internal phospholipid synthesis
Kota Nakajima1, Shunsuke Okada2, Hiroshi Ueno1, Naoki Soga1, Takahiro Muraoka2, Hiroyuki Noji1(1Dept. Appl. Chem., Grad. Sch. Eng., Univ. Tokyo, 2Dept. Appl. Chem., Grad. Sch. Eng., Tokyo Univ. Agri.
Tech.)
細菌アクチン MreB からスピロプラズマ遊泳モーターへの進化
Development of Spiroplasma swimming motor from bacterial actin, MreB
Daichi Takahashi1, Ikuko Fujiwara1,2, Makoto Miyata1,2 (1Grad. Sch. Sci., Osaka City Univ., 2OCARINA,
Osaka City Univ.)– S88 –

20429O

20430O

遺伝暗号における適応度地形の解析
Analysis of the fitness landscape of the genetic code
Yuji Omachi1, Nen Saito1, Chikara Furusawa1,2 (1Grad. Sch. Sci. UTokyo, 2RikenBDR)~Parasite による Host 多様化の促進~ 原始的な多様性は如何にして生まれたか？
Host diversification promoted by parasites: prebiotic diversity in evolution
Rikuto Kamiura1,2, Norikazu Ichihashi1,2 (1Graduate School of Arts and Science, The University of Tokyo,
2Komaba Institute of Science, The University of Tokyo)

P .ゲノム生物学・生命情報科学: ゲノミクス・分子進化／P. Genome biology & Bioinformatics
20431P

20432P

20433P*

20434P
20435P*

20436P

20437P*

20438P

20439P

Selection originating from protein stability/foldability: Relationships between protein folding freeenergy, sequence ensemble and fitness
Sanzo Miyazawa
自己集合ペプチドのオリゴマー形成に関する分子動力学的解析
Capturing oligomerization process of self-assembly peptides by using molecular dynamics
simulations
Kota Kasahara1,3, Junya Okigawa1, Hiroki Terazawa2, Qilin Xie3, Satoshi Goto2, Hayato Itaya2,
Katsufumi Nakayama3, Takuya Takahashi1 (1Coll. Life. Sci., Ristumeikan Univ., 2Grad. Sch. Life Sci,
Ritsumeikan Univ., 3Coll. Pharm. Sci., Ritsumeikan Univ.)
Protein Data Bank に基づくタンパク質-ペプチド結合予測のための相互作用パターンの網羅的な分類と分析
Comprehensive classification and analysis of interaction patterns for protein-peptide binding
prediction based on the Protein Data Bank
Keiichiro Sato1, Kota Kasahara1,2, Takuya Takahashi1,2 (1Grad. Sch. Life Sci., Ritsumeikan Univ., 2Coll.
Life Sci., Ritsumeikan Univ.)
演題取り消し荷電性残基の分布がタンパク質の液-液相分離に与える影響の解明に向けた分子動力学シミュレーション
Molecular dynamics simulations to dissect effects of charge distributions in protein sequence on
the liquid-liquid phase separation
Hiroki Terazawa1, Junya Okigawa2, Kota Kasahara2, Hiroshi Imamura2, Minoru Kato2,
Takuya Takahashi2 (1Grad. Sch. Life Sci, Ritsumeikan Univ., 2Coll. Life Sci, Ritsumeikan Univ.)
分子動力学シミュレーションによるアクチン構造ゆらぎの解析
Structural flexibility of actin studied by molecular dynamics simulation
Ryotaro Koike, Motonori Ota (Grad. Sch. Info., Nagoya Univ.)
PC4 天然変性領域の VP16 結合の制御メカニズムの解明
Simulation study of the mechanism of PC4 unstructured region which regulates binding with VP16
Qilin Xie1, Kota Kasahara2, Masafumi Nakayama1, Takuya Takahashi2 (1Coll. Pha Sci., Ritsumeikan Univ.,
2Coll. Life Sci., Ritsumeikan Univ.)
ウニ初期胚の核及び核内動態の蛍光イメージング観察・解析
Imaging analysis of inter- and intra-nuclear dynamics of sea urchin embryo
Miko Imada1, Ayaka Sugiyama2, Sayaka Hayashi2, Kaichi Watanabe1, Yuhei Yasui1, Naoaki Sakamoto1,
Akinori Awazu1 (1Dept. Math and Life Sciences, 2Dept. Math and Life Sciences)
不凍タンパク質の予測及び解析
Prediction and analysis of antifreeze protein
Ryosuke Miyata, Kentaro Shimizu, Tohru Terada, Yoshitaka Moriwaki (Dept. of Biotechnol., Grad. Sch.
of Agri. and Life Sci., Univ. of Tokyo)– S89 –

20440P

20441P

20442P

20443P

20444P

20445P

20446P

20447P

20448P*

20449P

20450P*

20451P

酵母の胞子形成の時系列マイクロアレイデータに対する効果的な非階層的クラスタリング手法開発の検討
Consideration of efficient non-hierarchical clustering method for time series microarray data ofsporulation of S. cerevisiae
Aoi Tani1, Masahiro Sugimoto2, Takanori Sasaki1 (1Fac. Adv. Math. Sci., Meiji Univ., 2RDCMIT, Tokyo
Med. Univ.)
DTX: 新規ヒト創薬ターゲット探索のための統合化ウェブツールの開発
DTX: An integrative web tool for exploring new potential drug targets in humans
Atsushi Hijikata, Masafumi Shionyu, Tsuyoshi Shirai (Facult. Biosci, Nagahama Inst. Bio-Sci. Tech.)
DR-SIP: Predicting the Quaternary Structures of Homo-oligomeric Transmembrane Proteins
Wai Soon Chan1,2,3, Jinhao Zhou2,4, Christopher Llynard Ortiz2, Chi-Hong Chang Chien2,
Rong-Long Pan2, Lee-Wei Yang2,3,5 (1BioMol. Sim. Grp., Kansai Photon Sci. Inst., QST, Japan, 2Inst. of
BioInfo. and Struct. Bio., Nat. Tsing Hua Uni., Taiwan, 3BioInfo., TIGP, Inst. of Info. Sci., Academia Sinica,
Taiwan, 4UTHealth Grad. Sch. of Biomed. Sci., Uni. of Texas, USA, 5Phys. Div., Nat. Center for Theoretical
Sci., Nat. Tsing Hua Uni., Taiwan)
機械学習を利用した scRNAseq からの空間的遺伝子発現パターンの再構成
Prediction of spatial gene expressions from scRNAseq data by machine learning
Yasushi Okochi1,2, Shunta Sakaguchi3, Ken Nakae4, Takefumi Kondo3,5, Naoki Honda1,6,7 (1Laboratory
for Theoretical Biology, Graduate School of Biostudies, Kyoto University, 2Faculty of Medicine, Kyoto
University, 3Laboratory for Cell Recognition and Pattern Formation, Graduate School of Biostudies, Kyoto
University, 4Graduate School of Informatics, Kyoto University, 5K-CONNEX, 6Research Center for
Dynamic Living Systems, Kyoto University, 7Theoretical Biology Research Group, ExCELLS)
蛍光増強 RNA アプタマーと cDNA ディスプレイを用いた高感度抗原検出法の開発
Development of a highly sensitive antigen detection method using fluorescence-enhanced RNA
aptamer and cDNA display
So Higashide, Naoto Nemoto (Graduate School of Science & Engineering, Saitama-University)
機械学習を用いた PLP 結合タンパク質の予測
Prediction of PLP-binding proteins by using machine learning-based methods
Masafumi Shionyu, Tomohiro Hatta, Atsushi Hijikata (Fac. Biosci., Nagahama Inst. Bio-Sci. Tech.)Formation of chromatin remodeler Chd1-ADP-Pi analogues ternary complexes which mimictransient states in ATPase cycle
MD Noor A Alam, Sadakane Kei, Maruta Shinsaku (SOKA UNIVERSITY)
細胞イメージングへの応用のための蛍光増強アプタマーの開発
Development of fluorescence enhancement aptamers of dye for cell imaging applications
Tomoyuki Koike1, Takashi Kubo1, Kenjiro Hanaoka2, Mitsuyoshi Ueda3, Koichi Kuroda3, Naoto Nemoto1(1Graduate School of Science and Engineering, Saitama University., 2Graduate School of Pharmaceutical
Sciences, The University of Tokyo., 3Graduate School of Agriculture, Kyoto University.)
マルチタスク学習を用いたタンパク質-リガンド結合部位の統合的な予測
Integrated prediction of protein-ligand binding sites using multi-task learning
Haruka Nakashima, Yoshitaka Moriwaki, Tohru Terada, Kentaro Shinizu (Dept. of Biotechnol., Grad.
Sch. of Agri. and Life Sci., Univ. of Tokyo)
電顕フィッティング計算のための高速な原子モデルの GMM への変換：PCA ボックスダウンサン
プル法
Fast calculation of Gaussian mixture models for atomic models to fit them on electron microscopy
map: PCA-box down-sampling method
Takeshi Kawabata, Haruki Nakamura, Genji Kurisu (IPR, Osaka U.)
GPCR オリゴマーに影響を及ぼすがん関連ホットスポット変異の予測
Prediction of cancer associated hotspot mutations that affect GPCR oligomerization
Sakie Shimamura1, Vachiranee Limviphuvadh2, Hiroyuki Toh3, Wataru Nemoto1 (1Dept. Sch. & Tech.,Tokyo Denki Univ., 2A*STAR, BII., 3Sch. of Sci. & Tech., Kwansei Gakuin Univ.)
Remodelers exploit spontaneous nucleosome fluctuations to reorganize chromatin
Giovanni Brandani, Shoji Takada (Kyoto University, School of Science)– S90 –

20452P

20453P

20454P*

20455P*

20456P
20457P

20458P*

電顕画像と立体構造情報との照合による膜タンパク質ファミリーの判別技術開発
Development of membrane protein family identifier by collating EM images and atomic coordinate
data
Ryuji Shinozaki1, Masami Ikeda2, Chikara Sato3, Makiko Suwa1 (1College of Sci. and Eng., Aoyamagakuin
Univ., 2AIRC, AIST, 3Health med., AIST)
Analysis of Genetic Variants Through Protein and Residue Sociability
Hafumi Nishi1,2, Yuki Kagaya1, Matsuyuki Shirota3, Kengo Kinoshita1 (1Grad. Sch. Info. Sci., Tohoku
Univ., 2Faculty Core Res., Ochanomizu Univ., 3Sch. Med., Tohoku Univ.)
タンパク質機能部位予測に適切な相同配列群選択手法の構築
Construction of a set of appropriate homologous sequences to predict functional regions of aproteinYuto Takahashi1, Shoichiro Kato1, Hiroyuki Toh2, Wataru Nemoto1 (1Dept. Sch. & Tech., Tokyo Denki
Univ., 2Sch. of Sci. & Tech., Kwansei Gakuin Univ.)
転写翻訳系とゲノムが同種の無細胞ゲノム転写翻訳系の確立
In vitro genome transcription-translation system using Escherichia coli systems
Yukino Matsui, Tatsuki Deyama, Nobuhide Doi, Kei Fujiwara (Dept. Biosci. Info., Keio univ.)
A comparative study of external morphology and phylogeny in the two species of earthworms
Hayato Endou (Oyama Highschool)
Protein-Protein interaction patterns distinguish the hearing-loss phenotype between syndromic
and non-syndromic types
Thi Thu Ha Duong1,2, Kei Yura1,3,4 (1Graduate School of Humanities and Sciences, Ochanomizu
University, 2-1-1 Otsuka, Bunkyo, Tokyo 112-8610, Japan, 2nstitute of Genome Research, Vietnam
Academy of Science and Technology, 18 Hoang Quoc Viet, Cau Giay, Ha Noi, Vietnam, 3Center forInterdisciplinary AI and Data Science, Ochanomizu University, 2-1-1 Otsuka, Bunkyo, Tokyo 112-8610,
Japan, 4Graduate School of Advanced Science and Engineering, Waseda University, 3-4-1 Okubo,
Shinjuku, Tokyo 169-8555, Japan)
PLA2 産生に関与する遺伝子と経路の同定
Identification of the genes and pathways responsible for PLA2 production
Eri Hayashi1, Yuto Kimura1, Shuichi Hirose2, Satoko Nakamura3, Norimasa Kashiwagi3, Chiaki Ogino3,4,
Wataru Nemoto1 (1Dept. Sch. & Tech., Tokyo Denki Univ., 2NAGASE R&D Center, 3hem Sci. & Eng.,
Grad. Sch. of Eng., Kobe Univ., 4Org. of Adv Sci & Tec., Kobe Univ.)
Q. 生態・環境／Q. Ecology & Environment

20459Q

20460Q

20461Q

20462Q

栄養構造を持つ 12 種微生物の人工生態系における確率現象
Stochastic phenomena in synthetic ecosystems of 12 microbial species with a trophic structure
Kazufumi Hosoda1, Naomi Murakami1, Shigeto Seno2, Yutaka Osada3, Hideo Matsuda2,
Chikara Furusawa4, Michio Kondoh5 (1ITGP, Osaka univ., 2IST, Osaka univ., 3FRA, 4Sci, Univ. Tokyo /BDR, Riken, 5Life sci, Tohoku univ.)
蝶の模様の多様性と複雑性は、やわらかい要素やかたい要素を組み合わせて進化してきた
Combinations of flexible and fixed components facilitate colorful divergence and complexity inbutterflies
Takao Suzuki (Grad. Sch. Sci., Univ. Tokyo)
大阪府の石川における外来のアメリカツノウズムシの繁殖生態
The breeding ecology of the invasive alien Planaria, Girardia dorotocephala, in the middle reachesof the Isikawa river in Osaka Pref
Sakura Takahashi (Osaka Pref. Tondabayashi H.S.)
マミズクラゲの無性世代の 2 つの芽体を決める生息条件について
The habitat conditions determined two types of sprout formation of the asexual generation ofFreshwater jellyfish, Craspedacusta sowerbii
Yuki Tanino, Yuta Hirayama, Sota Moriyama (Osaka Pref.Tondabayashi H.S.)– S91 –

20463Q

20464Q

20465Q

20466Q

20467Q

金剛山地(大阪府)におけるヨツワクガビルの生息環境について
The Habitat of the Orobdella whitmani Oka in the Kongo Mountains (Osaka pref.)Yuya Uenishi (Osaka pref. Tondabayshi H.S.)
大阪府で初めて繫殖を確認したイワナ Salvelinus leucomaenis の生態とその由来の研究
The study of the ecology and origin of Salvelinus leucomaenis that has been confirmed to breed
for the first time in Osaka prefecture
Kanato Nakamura, Kaito Oana (Osaka pref. Tondabayashi H.S.)
三面コンクリート張り水路でゲンジボタルが生息できる理由
Reasons why Japanese Firefly, Luciola cruciate, can inhabit in a three-sided concrete channel
Takumi Matsuo, Tomoki Ikegawa (Osaka Pref. Tondabayashi H.S.)
海浜植物のハマヒルガオが浜辺で生育できる理由
Reasons why the beach plant, Calystegia Soldanella, can grow on the beach
Kei Yanazawa (Osaka Pref. Todabayashi H.S.)
ドジョウの繁殖行動を誘発するトリガーについて
Triggers that trigger breeding behavior in loaches, Misgurnus anguillicaudatus,
Yohei Okugawa (Osaka Pref. Tondabayashi H.S.)

R. 数理生物学・非平衡・生体リズム／R. Mathematical biology, Nonequilibrium state & Biological rhythm
20468R

20469R

20470R

20471R*

20472R
20473R

20474R
20475R

Fisher 情報量による ERK リン酸化ダイナミクスの熱力学的性質の解明
The Fisher information of time reveals the thermodynamic property of ERK phosphorylation
dynamics
Keita Ashida1, Yohei Kondo2,3,4, Kazuhiro Aoki2,3,4, Sosuke Ito1,5 (1Universal Biology Institute, The
University of Tokyo, 2Exploratory Research Center on Life and Living Systems (ExCELLS), National
Institutes of Natural Science, 3National Institute for Basic Biology, National Institutes of Natural Sciences,
4Department of Basic Biology, School of Life Science, SOKENDAI, 5JST, PRESTO)
Life-logger, 1000 匹の線虫の寿命時間スケールでの行動動態を計測するためのビデオ撮影装置の開発
Life-logger, a video-recorder of crawling motion of 1,000 C. elegans individuals during theirlifespan
Yukinobu Arata, Peter Jurica, Yasishi Sako (Cellular Informatics Laboratory, Riken)
度数情報だけで再訪性を判断するエージェントのネットワーク探索
A Random walk model on the Scale-Free Network with the Cognitive Biases
Koji Takashima, Tomoko Sakiyama (Soka University)
遺伝子発現レベルの情報から ErbB シグナルの動態を予測する数理モデリング基盤の開発
Model-based prediction of ErbB signaling dynamics solely from the information about gene
expression levels
Hiroaki Imoto, Marie Maeda, Suxiang Zhang, Mariko Okada (IPR, Osaka Univ.)
Approximation of transition density of the conductance based neuronal model with noise
Takanobu Yamanobe (Sch. Med., Hokkaido Univ.)
人工トリペプチドからなる自己集合性ナノファイバーの進行波による力発生
Force generation by a propagating wave of artificial tripeptide-based fibrous assemblies
Ryou Kubota1, Masahiro Makuta2, Ryo Suzuki3, Masatoshi Ichikawa2, Motomu Tanaka3, Itaru Hamachi1,4(1Grad. Eng., Kyoto Univ., 2Grad. Sci., Kyoto Univ., 3Inst. Adv. Stud., Kyoto Univ., 4JST ERATO)
Quantifying expressive power of gene regulatory systems
Yohei Kondo1,2, Kazuhiro Aoki1,2,3 (1ExCELLS, 2SOKENDAI, 3NIBB)
質量保存を満たす反応拡散系にみられる相分離的な挙動
Phase-separation like behavior in mass-conserved reaction diffusion systems
Michio Tateno, Shuji Ishihara (Shuji Ishihara Lab., Graduate School of Arts and Sciences, The Universityof Tokyo)– S92 –

20476R

20477R

20478R

20479R

20480R

20481R

20482R

20483R

20484R*

20485R

20486R

20487R
20488R

Investigation of related genes in the development of atopic dermatitis by geometric feature
extraction from gene expression patterns
Takuya Hasebe1, Masahiro Sugimoto2, Takanori Sasaki1 (1Grad. Sch. Adv. Math. Sci., Meiji Univ,
2RDCMIT, Tokyo Med. Univ)
脳神経系の可塑的結合力学系モデルにおける自己組織的ネットワーク
Self-organized network structures in coupled dynamical system with connection plasticity inspiredby cerebral nervous system
Amika Ohara, Masashi Fujii, Akinori Awazu (Dept. of math. and life sci. Hiroshima univ.)
ディープラーニング及びオートエンコーダーを用いた乳癌組織中の DEGs からの特徴抽出と予後予測
Feature extraction and prognosis prediction from DEGs in breast cancer tissue using Deeplearning and Autoencoder
Yusuke Mizukoshi1, Masahiro Sugimoto2, Takanori Sasaki1 (1Fac. Adv. Math. Sci., Meiji Univ.,
2RDCMIT, Tokyo Med. Univ.)
Determination of the interacting time between KaiA and KaiB during clock oscillation
Risa Mutoh1, Takahiro Iida1, Mino Hiroyuki2 (1Faculty of Sci. Fukuoka Univ., 2Grad. Sch. of Sci., Nagoya
Univ.)
オンチップ単一細胞培養システムによる 3 細胞系心筋ネットワークの拍動同期過程の観察
Observation of synchronized beating cycles of cardiomyocytes during three cell network formationin on-chip single cell measurement assay
Yoshitsune Hondo1, Kazufumi Sakamoto1, Rikuto Sekine2, Yuhei Tanaka1, Haruki Watanabe1,
Kenji Shimoda1, Kenji Yasuda1,2 (1Dept. Pure & Appl. Phys., Grad. Sch. Adv. Sci. & Eng., Waseda Univ.,
2Dept. Pure & Appl. Phys., Sch. Adv. Sci. & Eng., Waseda Univ.)
Active Inference of Gradient in Reward-oriented Behavior
WeiQing Chen1, Naoki Honda1,2 (1Grad. Sch. Bio., Univ. Kyoto, 2Theoretical Biology Research Group,
Exploratory Research Center on Life and Living Systems (ExCELLS), National Institutes of Natural
Sciences, Okazaki, Aichi, Japan.)
膜タンパク質のクラスター形成機構の数理的研究
A Mathematical study on the mechanism of cluster formation of membrane proteins
Hiroaki Takagi (Sch. Med., Nara Med. Univ.)
ES 細胞分化初期における染色体動態
The dynamics of chromosomes on early differentiation stage from ES cell
Tetsushi Komoto, Masashi Fujii, Akinori Awazu (Hiroshima univ. Grad. Sch. Integrated Sciences for Life)
Inferring domain of Interactions among Dictyostelium discoideum colony from the Ensemble ofTrajectories of cells
Udoy S. Basak1,2, Sulimon Sattari1, Md. Motaleb Hossain1, Kazuki Horikawa3, Tamkiki Komatsuzaki1(1Hokkaido University, 2Pabna University of Science and Technology, 3Tokushima University)
栄養の枯渇が引き起こす酵母の解糖系振動現象
Glycolytic Oscillation in Yeast Induced by Nutrient Depletion
Seiji Hatano1, Noboru Nagata1, Yutetsu Kuruma2, Toshihiro Kawakatsu1, Masayuki Imai1 (1Grad. Sch.
Sci., Tohoku Univ., 2ELSI, Tokyo Inst. Tech.)
ミトコンドリア呼吸鎖エナジェティクスの速度論的解析
Kinetic analysis of energetics in mitochondrial respiratory chain
Ikuo Kujiraoka1, Kotaro Takeyasu2,3, Junji Nakamura2,3 (1Graduate school of science and technology,
Univ. Tsukuba, 2Faculty of pure and applied sciences, Univ. Tsukuba, 3Tsukuba research center for energy
materials science, Univ. Tsukuba)
Chromatin dynamics in Hox-mediated animal body development
Yoshifumi Asakura1, Naoki Honda1,2 (1Grad. Sch. Biostudies, Univ. Kyoto, 2ExCELLS, NINS)
エピジェネティック修飾の変化の影響を考慮した EM 遷移のシミュレーション
A model on the effects of epigenetic modification on epithelial-mesenchymal transitions (EMT)
Kenichi Hagiwara, Masaki Sasai (Dept.Appl.phys.,Nagoya Univ.)– S93 –

20489R

20490R

20491R

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20494R

20495R

20496R

20497R

20498R

20499R*

20500R*

Length scale-dependent relaxation in chromatin with and without the transcription factory
Ashwin S. S1, Yuji Itoh2, Kazuhiro Maeshima2, Masaki Sasai1 (1Department of Applied Physics, Nagoya
University, Nagoya, JAPAN, 2Structural Biology Center, National Institute of Genetics, Mishima, JAPAN)
出芽酵母の DNA 二本鎖切断時における染色体動態の数理モデル
A mathmatical model of chromosomal dynamics in budding yeast during DNA double strand breakShinjiro Nakahata, Akinori Awazu, Masashi Fujii (Hiroshima univ. Grad. Sch. Integrated Sciences forLife)
Quantifying the length- and time-scales of influence of cells in collective motion
Sulimon Sattari1, Udoy Basak1, Md. Hossain Motaleb1, Kazuki Horikawa2, Tamiki Komatsuzaki1(1Hokkaido University Research Institute for Electronic Science, 2Tokushima Unviersity, Institute of
Biomedical Sciences)
Circular probability currents and correlation functions for gene switching coupled with epigenetic
dynamics
Bhaswati Bhattacharyya, Masaki Sasai (Department of Applied Physics, Graduate School of Engineering,
Nagoya University)
植物のストレス応答を担う植物ホルモン時空間動態の数理モデル
Mathematical model of spatiotemporal dynamics of plant hormones responsible for plant stressresponse
Mariko Arimoto, Akinori Awazu, Masashi Fujii (Grad. Sch. Sci., Univ. Hiroshima)
協同的に振る舞う遺伝子発現制御ネットワークの定量的解析
Quantitative analysis of cooperative network from sloppy gene expression dynamics
Masayo Inoue1, Kunihiko Kaneko2 (1IMS, Meiji Univ., 2Univ. of Tokyo)
ヒトゲノム中の 3 塩基リピート配列周辺エピゲノムとクロマチン構造のゲノムワイドな解析
Genome-wide analysis of epigenetic and chromatin-structural features around triplet repeat
sequences in human genome
Kenji Ojima1, Yuudai Hirose2, Masashi Fujii1, Akinori Awazu1 (1Department of Mathematical and Life
Sciences, Graduate School of Integrated Sciences for Life, Hiroshima University, 2Department ofMathematical and Life Sciences, Graduate School of Science, Hiroshima University)
バクテリアの集団運動による走性の変化
Enhanced bacterial taxis by collective movement
Tatsuro Kai, Takahiro Abe, Shuichi Nakamura, Seishi Kudo, Shoichi Toyabe (Department of Applied
Physics, Graduate School of Engineering, Tohoku University)
Fluctuation distribution of propagation time was conserved during excitation conduction in linedup cardiomyocyte networks
Kazufumi Sakamoto1, Yoshitsune Hondo1, Kenji Yasuda1,2 (1Dept. Pure & Appl. Phys., Grad. Sch. Adv.
Sci. & Eng., Waseda Univ., 2Dept. Pure & Appl. Phys., Sch. Adv. Sci. & Eng., Waseda Univ.)
Vector analysis of amoeba motion with respect to the propagation of chemoattractant cyclic-AMP
Vector analysis of amoeba motion with respect to the propagation of chemoattractant cyclic-AMP
Md. Motaleb Hossain1,2, Sulimon Sattari1, Udoy S Basak1, Kazuki Horikawa3, Tamiki Komatsuzaki1(1Hokkaido University, 2University of Dhaka, 3Tokushima University)
免疫系の記憶ダイナミクスにおける適応的な抗原の有害・無害識別Adaptive Discrimination of Risk of Antigens in Immune Memory Dynamics
Kana Yoshido1, Naoki Honda1,2 (1Grad. Sch. Biostudies, Univ. Kyoto, 2ExCELLS, NINS)ERK シグナル伝達系の進化生化学
Evolutionary biochemistry of ERK signaling network
Masaya Mukai1,2,3, Yohei Kondo2,3, Kazuhiro Aoki1,2,3 (1Division of Quantitative Biol., NIBB,
2Quantitative Biol. Group, ExCELLS, 3Dept. of Basic Biol., Sch. of Life Sci., SOKENDAI)– S94 –

S. 計測・バイオイメージング／S. Measurements ＆ Bioimaging
20501S

20502S

20503S

20504S

20505S*

20506S

20507S

20508S

20509S

20510S

BSA における AQDS 結合サイトの光誘起電子電子二重共鳴(DEER)計測
Light-induced DEER measurement on the AQDS-binding site in Bovine Serum Albumin
Hiroki Nagashima, Lewis Antill, Kiminori Maeda (Dep. Chem., Grad. Sch. Sci., Saitama University)
ヒト皮膚または培養皮膚に貼付したセラミド含有粘着性ゲルシートからのセラミド放出のマイクロ FT-IR 分光法による計測
Micro FT-IR Spectroscopic Study on Ceramide-release from Ceramide-Containing Adhesive Gel
Sheet Affixed to Human Skin or Cultured Skin
Hiroshi Takahashi1, Ryota Watanabe2, Kenichi Nishimura2, Taro Moriwaki3 (1Grad Sci Sci.&Tech.,Gunma Univ., 2ALCARE Co., Ltd., 3JASRI/SPring-8)
ウニの発生初期における核内染色体構造の動的および細胞特異的変化
Dynamic and cell specific changes in intranuclear chromosomal structures during early
development of sea urchin
Yuhei Yasui, Ayaka Sugiyama, Naoaki Sakamoto, Akinori Awazu (Integrated science for life, Hiroshima
University)
伝導度計測を用いたペプチドのリン酸化の単一分子検出
Single-molecule detection of peptide phosphorylation using electrical conductance measurement
Takanori Harashima1, Yoshiyuki Egami2, Tomoya Ono3, Tomoaki Nishino1 (1School of Science, Tokyo
Institute of Technology, 2Faculty of Engineering, Hokkaido University, 3Department of Electrical andElectronic Engineering, Kobe University)
イオン液体-スピン乾燥法で走査型電子顕微鏡の試料作製を容易にする
A simple and quick method to prepare biological specimens for scanning electron microscopy byan ionic liquid
Tatsuya Suehiro, Naoki Uemura, Saki Taguchi, Katsuya Shimabukuro (Chem. Bio. Eng., NIT Ube
College)
短波赤外光を発する量子ドットによる無侵襲マウス脳表血管造影とその焦点合わせについて
Novel angiography for mouse cerebral vasculature using short-wave infrared light emitting
quantum dots and its focusing
Tatsuto Iida1, Hiro Yamato1, Takashi Jin2, Yasutomo Nomura1,2 (1Department of Systems Life
Engineering, Maebashi Institute of Technology, 2RIKEN Center for Biosystems Dynamics Research)
Variogram/Correlogram 法を使った生物対流解析
Variogram and correlogram assay of cell motility: Bioconvection in harmful algae Chattonella
Mina Nakahara, Atsuto Kobayashi, Shinji Kamimura (Dept. Biol. Sci., Fac. Sci. & Eng., Chuo Univ.)
分裂期の染色体の 3D-AFM 像の理論予測と実測との比較
A theoretical prediction of 3D atomic force microscopy image of chromosomes in mitotic phaseand its comparison with experiments
Takashi Sumikama1, Keisuke Miyazawa1,2, Makiko Meguro-Horike3, Ryohei Kojima2, Naoko Okano2,
Shin-ichi Horike3, Adam S. Foster1,4, Takeshi Fukuma1,2 (1Nano Life Sci. Inst. (WPI-NanoLSI), Kanazawa
Univ., 2Grad. Sch. of Nat. Sci. and Tech., Kanazawa Univ., 3Div. of Func. Gen., Adv. Sci. Res. Center,
Kanazawa Univ., 4Dept. of Appl. Phys., Aalto Univ.)
原子間力顕微鏡の位相イメージングを用いた Paracoccus denitrificans 細胞に結合した膜小胞の解析
Analysis of bacterial extracellular membrane vesicles bound to Paracoccus denitrificans cell byatomic force microscopy phase imaging
Yousuke Kikuchi1, Yuuki Ichinaka1, Masanori Toyofuku2,3, Nozomu Obana3,4, Nobuhiko Nomura2,3,
Azuma Taoka1,5 (1Col. of Sci. and Eng., Kanazawa Univ., 2Life and Env. Sci., Tsukuba Univ., 3MiCS,
Tsukuba Univ., 4Trans. Med. Res., Tsukuba Univ., 5WPI-NanoLSI, Kanazawa Univ.)
神経細胞分化における細胞内温度の関与
Involvement of intracellular temperature in neuronal differentiation
Shunsuke Chuma1, Kohki Okabe2,3, Yoshie Harada1,4 (1IPR, Osaka Univ., 2Grad. Sch. Pharm. Sci., The
Univ. Tokyo, 3PRESTO, JST, 4QIQB, OTRI, Osaka Univ.)– S95 –

20511S

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20520S

原子間力顕微鏡と多孔窒化シリコン薄膜を用いた生きた細胞表面の高分解能観察方法の開発
Development of high-resolution observation method of living cell surface in atomic force
microscope using porous silicon nitride membrane
Takehiko Ichikawa1, Taiki Kitamura2, Dong Wang1,3, Hiroko Oshima3, Masanobu Oshima1,3,
Takeshi Fukuma1,2 (1NanoLSI, Kanazawa Univ., 2College of Science and Engineering, Kanazawa Univ.,
3Cancer Research Institute, Kanazawa Univ.)
自動イオンチャネル電流測定装置の開発
Development of a system for automated ionic current measurement
Minako Hirano1, Masahisa Tomita2, Chikako Takahashi1, Nobuyuki Kawashima2, Toru Ide3 (1Grad. Sch.
Creation Photon Indust., 2SYSTEC Corporation, 3Okayama Univ.)
上皮成長因子受容体癌変異への自動化 1 分子解析の薬理学的応用
Pharmacological application of automated single-molecule analysis for EGFR cancerous
mutants
Michio Hiroshima1,2, Daisuke Watanabe3, Masahiro Ueda1,3 (1RIKEN BDR, 2RIKEN CPR, 3FBS, Osaka
Univ.)
生細胞 1 分子超解像イメージングによるヒストンバリアントのナノスケール局在解析
Nano-scale localization analysis of histone variants in living cells using single-molecule superresolution imaging
Yuma Ito, Makio Tokunaga (Sch. Life Sci. Tech., Tokyo Tech)
サブミリ秒光波面シェイピングシステムによる厚さ 2mm の鶏肉を通した光集束及び蛍光イメージ
ング
Optical focusing and fluorescence imaging through a 2mm thick chicken tissue slice bysubmillisecond wavefront shaping system
Atsushi Shibukawa, Keiichi Kojima, Yuki Sudo (Grad. Sch. of Med. Dent. Pharm. Sci., Okayama Univ.)
Development of continuous non-clogging cell fractionation technique using pillar arrangement andAC electric field
Kaito Asahi1, Moe Iwamura2, Masao Odaka3,4, Akihiro Hattori3,4, Kenji Yasuda1,2,3,4 (1Dept. Phys. Sch.
Adv. Sci. & Eng., Waseda Univ., 2Dept. Pure & Appl. Phys., Grad. Sch. Adv. Sci. & Eng., Waseda Univ.,
3Org. Univ. Res. Initiatives, Waseda Univ., 4WASEDA Biosci. Res. Ins. in Singapore)
Interaction of nicked-DNA with solid state nanopores
Shimba Ichino, Kento Lloyd, Takumi Yoshikawa, Ryoma Omori, Yuuta Moriyama,
Toshiyuki Mitsui (Aogaku Univ.)
Simple precise flow speed measurement in an on-chip flow cytometer with simultaneous twowavelength differential image analysis
Toshinosuke Akimoto1, Shuya Sawa1, Masao Odaka3, Akihiro Hattori3, Mitsuru Sentoku1,
Hiromiti Hasimoto2, Kaito Asahi1, Kenji Yasuda1,2,3 (1Dept. Phys., Sch. Adv. Sci. & Eng., Waseda Univ.,
2Dept. Pure & Appl. Phys., Grad. Sch. Adv. Sci. & Eng., Waseda Univ., 3Org. Univ. Res. Initiatives,
Waseda Univ.)
多次元デジタルバイオアッセイで明らかになった、インフルエンザウイルスにおける粒子ごとの薬剤応答の多様性
Multi-Dimensional (MD) Digital Bioassay unveils heterogeneous drug-susceptibility of influenza A
virus in a single-virus resolution
Shingo Honda1, Kazuhito V. Tabata2, Yoshihiro Minagawa2, Hiroyuki Noji1,2 (1Dept. Bioeng., Grad. Sch.
Eng., Univ. Tokyo, 2Dept. Appl. Chem., Grad. Sch. Eng., Univ. Tokyo)
Ligand is not necessary for progress of engulfment in IgG-coated and non-coated mixture of
antigen cluster
Amane Yoshida1, Yuya Furumoto1, Toshiki Azuma1, Tomoyasu Sakaguchi1, Kenji Yasuda1,2,3 (1Dept.
Pure & Appl. Phys., Grad. Sch. Adv. Sci. & Eng., Waseda Univ., 2Org. Univ. Res. Initiatives, Waseda Univ.,
3WASEDA Biosci. Res. Ins. in Singapore (WABIOS))– S96 –

20521S

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20524S*

20525S

20526S

20527S

20528S

20529S
20530S

20531S

20532S

光ファイバー型蛍光相関分光装置を用いたエクソソームの同定
Identification of exosome by using optical fiber based fluorescence correlation spectroscopy
Misato Osaka1, Johtaro Yamamoto2,3, Masataka Kinjo3 (1Grad. Sch. of Life Sci., Hokkaido Univ., 2Health& Med. Res. Inst., AIST, 3Fac. of Adv. Life Sci., Hokkaido Univ.)
最大エントロピー法と変分ベイズクラスタリングを用いた 1 分子 FRET データ解析による細胞質
中 RAF のダイマー化状態の検出
Dimer formation of cytosolic RAF detected by single-molecule FRET analysis based on maximum
entropy and variational Bayes-culstering
Kenji Okamoto, Yasushi Sako (RIKEN CPR)
Investigation of automatic single-molecule tracking method for large-scale single-molecule
imaging analysis
Sotaro Mori1, Masato Yasui4, Satomi Matsuoka1,2,3,5, Masahiro Ueda1,2,3 (1Grad. Sch. Sci., Univ. Osaka,
2Grad. Sch. Sci. of Front. Biosci., Univ. Osaka, 3BDR, RIKEN, 4ZIDO Corp., 5PRESTO, JST)
ヨーロッパモノアラガイの咀嚼神経系の蛍光 NO イメージング －味覚嫌悪学習前後の NO 放出の比較
Fluorescence NO imaging for feeding nervous system of the pond snail-Comparison of NO
release before and after taste-aversive conditioning
Ayaka Itoh1, Yoshimasa Komatsuzaki2, Minoru Saito1 (1Grad. Sch. of Int. Bas. Sci., Nihon Univ., 2Coll.
Sci. Tech., Nihon Univ.)
DNA ナノデバイスを用いた細胞の機械シグナルイメージング技術開発
Development of mechanical signal imaging technique using DNA nano-device
Hiroki Fukunaga1, Takahiro Saito1, Satiko Onishi2, Mitsuhiro Iwaki1,2 (1FBS, Univ. Osaka, 2BDR, Riken)
クロモセンター領域内外におけるヘテロクロマチンタンパク質 HP1α 動態の生細胞 1 分子イメー
ジング定量解析
Dynamics of Heterochromatin protein 1α inside and outside chromocenter domain in living cells
using single-molecule imaging
Masanori Nakano1, Yuma Ito1, Takahiro Maeda1, Chikashi Obuse2, Makio Tokunaga1 (1Sch. Life Sci.
Tech., Tokyo Inst. Tech., 2Biosci. Grad Sch Sci., Osaka Univ)
補償光学系を用いた 1 分子イメージングにおける収差補正のシミュレーション
Light field simulation of single-molecule imaging for aberration correction using adaptive optics
Xiang Zhou, Yuma Ito, Makio Tokunaga (Sch. Life Sci. Tech., Tokyo Tech.)
核小体タンパク質の多色超解像 1 分子イメージング解析
Multicolor single-molecule imaging analysis of the nucleolar proteins
Supanut Sirisukhodom1, Yuma Ito1, Noriko Saitoh2, Makio Tokunaga1 (1Sch. Life Sci. Tech., Tokyo Tech.,
2Div. of Cancer Biol., The Cancer Inst. JFCR.)
Development of an enzyme-coupled fluorometric digital bioassay for ATPase
Hiroshi Ueno, Mayu Hara, Mio Sano, Hiroyuki Noji (Dept. Appl. Chem., Grad. Sch. Eng., Univ. Tokyo)
2 光子生体イメージングでみるインフルエンザウイルス感染肺In vivo imaging of the cellular pathophysiology in influenza virus-infected mouse lung
Hiroshi Ueki1, Yoshihiro Kawaoka1,2,3 (1Division of Virology, Department of Microbiology and
Immunology, Institute of Medical Science, University of Tokyo, 2Department of Special Pathogens,International Research Center for Infectious Diseases, Institute of Medical Science, University of Tokyo,
3Department of Pathobiological Sciences, School of Veterinary Medicine, University of WisconsinMadison)
Direct observation of force-induced release of SecM translation arrest
Zhuohao Yang1, Ryo Iizuka1,2, Takashi Funatsu1 (1Grad. Sch. Pharm. Sci., The Univ. Tokyo., 2Dept. Biol.
Sci., Grad. Sch. Sci., The Univ. Tokyo)
パッチクランプ AFM の開発に向けて
Toward the development of Patch Clamp Atomic Force Microscopy
Takeru Matsubara1, Shinji Watanabe2, Toshio Ando2, Noriyuki Kodera2 (1Grad. Sch. NanoLS.,
Kanazawa Univ., 2WPI-NanoLSI, Kanazawa Univ.)– S97 –

20533S*

20534S*

20535S
20536S*

20537S*

20538S*

20539S*

20540S

20541S

20542S

20543S

Biophysical analysis of pH-dependent conformational change of LDLR family members in ligand
capture and release
Aki Shiozawa1, Noriyuki Kodera2, Terukazu Nogi1 (1Grad. Sch. of Med. Lif. Sci., Yokohama City Univ.,
2WPI-NanoLSI, Kanazawa Univ.)
客観的な生物物理学データ解析に向けた初期パラメータ設定を必要としない隠 れマルコフモデル
フィッティング手法の開発
Development of a new hidden Markov model fitting algorithm without predefinition of parameters
for objective biophysical data analysis
Hanjin Liu, Tomohiro Shima, Sotaro Uemura (Sch. Sci., Univ. Tokyo)
DNA motions near geometrically anisotropic nanopores
Takumi Yoshikawa, Ryoma Omori, Shimba Ichino, Yuuta Moriyama, Toshiyuki Mitsui (Aogaku Univ.)
統計的蛍光画像解析による濃度分布イメージング
Fluorescence Imaging for Concentration Based on Statistical Analysis
Ryosuke Fukushima1, Johtaro Yamamoto2,3, Masataka Kinjo3 (1Grad. Sch. of Life Sci., Hokkaido Univ.,
2Health & Med. Res. Inst., AIST, 3Fac. of Adv. Life Sci., Hokkaido Univ.)
Hybrid Photon Counting (HPC)検出器の microED 法への応用
Hybrid Photon Counting (HPC) detector application for microED method
Keigo Takahira1,2, Kotaro Tanaka1, Takeyoshi Taguchi2, Hiroyuki Kanda2, Akihito Yamano2,
Takuo Yasunaga1 (1Grad.Sch.Comp.Sci.Syst.Eng.,KIT,Fukuoka,Japan, 2Rigaku Corporation,Tokyo,Japan)
環境の温度変化に対する RNA の状態変化を介した細胞応答の解明
Investigating cell response to environmental temperature change via RNA state changes
Hiroki Shibata1, Kohki Okabe1,2, Takashi Funatsu1 (1Grad. Sch. of Pharm. Sci., The Univ of Tokyo,
2PRESTO, JST)繊毛虫 Tetrahymena による遊泳軌跡の三次元定量
Three-dimensional analysis of the swimming trajectories of Tetrahymena
Akisato Marumo, Kyohei Matsuda, Masahiko Yamagishi, Mitsuhiro Sugawa, Junichiro Yajima (Dept. Life
Sci., Grad. Arts & Sci., Univ. Tokyo)
相関顕微鏡法（CLEM）による同一試料観察に向けた相関・位置合わせ精度の改善
Improvement of correlation and alignment accuracy toward the same sample observation by
CLEM
Yuki Gomibuchi1, Risa Ezoe2, Hiroko Takazaki1,3, Yasuhisa Honda2, Yusuke V. Morimoto1,
Takuo Yasunaga1 (1Dept. of Phys. Info. Tech., Kyushu Inst. Tech, 2Dept. of Biosci. Bioinfo., Kyushu Inst.
Tech., 3IPR. Osaka Univ.)
画像解析システム Eos の次世代開発に向けて
Approach to the next generation of our developing image processing system, Eos
Takuo Yasunaga (Comp. Sci and Sys. Eng., Kyutech)
高速原子間力顕微鏡データと分子シミュレーションのデータ同化によるミオシン V の動的構造解析
Dynamic structure analysis of myosin V by data assimilation combining HS-AFM data andmolecular simulations
Sotaro Fuchigami1, Rie Koga2, Shoji Takada1 (1Grad. Sch. of Science, Kyoto Univ., 2ExCELLS, NINS)
水素化アモルファスシリコンと有機半導体で増強された分子薄膜を用いた揮発性 化合物のセンサ
システム
A sensor system for volatile organic compound using molecular film enhanced by hydrogenatedamorphous silicon and organic semiconductor
Hikaru Hatakeyama1, Kisiro Seino1, Shu Mugita1, Kairi Shimazaki1, Hiroshi Masumoto2,
Yutaka Tsujiuchi1 (1Material Science and Engineering, Akita University, 2Frontier Research Institute forInterdisciplinary, Tohoku University)– S98 –

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20549S*

20550S

水素化アモルファスシリコンの上に積層したバクテリオロドプシンの分子間相互作用と構造変化
Inter molecular interaction and structural change of bacteriorhodopsin film laminated onhydrogenated amorphous silicon film
Yutaka Tsujiuchi1, Hikaru Hatakeyama1, Koki Shimanaka1, Hiroshi Masumoto2 (1Mat.Sci.AkitaUNIV,
2Fris.TohokuUNIV)
粒子フィルター MD シミュレーションによる高速 AFM の非斉時ビデオのデータ同化
Particle-filter MD simulations to assimilate asynchronous video data of high-speed AFM
Suguru Kato, Sotaro Fuchigami, Shoji Takada (Kyoto University)
HPD を用いた広視野蛍光 1 分子検出による局所環境変化のモニタリング
Local ambient condition monitoring by hybrid photo-detector (HPD)-based wide-field singlemolecule fluorescence detection
Atsuhito Fukasawa1, Gaku Nakano1, Takayasu Nagasawa1, Minako Hirano2, Toru Ide3, Hiroaki Yokota2(1Hamamatsu Photonics K.K., 2Grad. Sch. Creation Photon Indust., 3Grad. Sch. Interdiscip. Sci. Eng.
Health Sys.)
多様な構造をもつタンパク質複合体の単粒子解析を改善する方法の調査研究
A survey and investigation on methods to improve single particle analysis of heterogeneous
protein complexes
Kotaro Tanaka, Takuo Yasunaga (Grad. Sch. Comp. Sci. Syst. Eng., Kyutech)
生物発光共鳴エネルギー移動による発光バクテリアルシフェラーゼの高輝度化
Enhanced brightness of bacterial luciferase by bioluminescence resonance energy transfer
Tomomi Kaku, Megumi Iwano, Tetsuyuki Entani, Kenji Osabe, Takeharu Nagai (The Institute of Scientificand Industrial Reseach, Osaka University)
Wash-free デジタルバイオ計測のための split enzyme の開発
Development of a split enzyme for wash-free digital bioassay
Yanbo Ma, Hiroshi Ueno, Hiroyuki Noji (Department of Applied Chemistry, Graduate School ofEngineering, University of Tokyo)
Raman imaging for cancer diagnosis
Clement Jean-Emmanuel1, Mochizuki Kenntaro2, Fujita Katsumasa3, Komatsuzaki Tamiki1 (1RIES
Hokkaido University, 2Kyoto University, 3Osaka University)

T .バイオエンジニアリング・結晶成長・結晶化技術／T. Bioengineering, Crystal growth & Crystallization
technique20551T

20552T

20553T

20554T

FRAP 法と遺伝子組換えを併用した反応拡散分子の細胞内動態解析
FRAP combined with genetic manipulation reveals the kinetics of actin-binding proteins in cells
Takumi Saito1,2, Daiki Matsunaga1, Tsubasa Matsui1, Kentaro Noi1, Shinji Deguchi1 (1Grad. Sch. Eng.
Sci., Osaka uni., 2JSPS Research Fellow)
高汎用性を目指した改良凝固ゲル中結晶化法の開発と評価
Development and evaluation of the high-strength hydrogel method for high versatility
Taichi Naruse1, Mihoka Amano1, Noriaki Kunimune2, Tsuguo Nagasawa2, Hiroaki Adachi3,
Yusuke Mori4, Shigeru Sugiyama5 (1Grad. Sch. Sci., Kochi Univ., 2KUNIMUNE Inc., 3SOSHO Inc., 4Grad.
Sch. Eng., Osaka Univ., 5Fac. Sci. & Tec., Kochi Univ.)
DNA オリガミによる人工 γ-TuRC
Artificial γ-TuRC made by DNA origami
Daisuke Inoue (Kyushu University)
集光レーザービームによる動的微小管ネットワークの形成
Formation of dynamic microtubule networks by focused laser beam
Kei Takano1, Takuya Takeshige1, Humika Kiryu1, Ryuzo Kawamura1, Chi-shiun Wu2, Shih Yang-Hshin2,
Seiichiro Nakabayashi1, Teruki Sugiyama2,3, Hiroshi Yoshikawa1 (1Grad. Chem., Saitama Univ., 2App.
Chem., National Chiao Tung Univ., 3Mate. Sci., Nara Inst. Sci. Tech. Univ.)– S99 –

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Combination approach for identification of highly-active mutant of processive chitinase
Akasit Visootsat1,2, Akihiko Nakamura3, Tak-Wai Wang4, Ryota Iino1,2 (1Department of Functional
Molecular Science, School of Physical Sciences, The Graduate University for Advanced Studies, 2Institutefor Molecular Science, 3Department of Applied Life Sciences, Faculty of Agriculture, Shizuoka University,
4Chimie ParisTech)
Culture-independent method for screening macromolecule-degrading microbes using
deformability-based microfluidic microdroplet sorting
Mikihisa Muta1, Kai Saito1, Ryo Iizuka1, Wataru Kawakubo2, Hyun Yoon Dong3, Tetsushi Sekiguchi3,
Shuichi Shoji2, Mei Ito4, Yuji Hatada4, Takashi Funatsu1 (1Grad. Sch. of Pharm. Sci., The Univ. of Tokyo,
2Dept. of Nanosci. and Nanoeng., Waseda Univ., 3Res. Org. for Nano & Life Innov., 4Dept. of Life Sci. andGreen Chem., Saitama Inst. of Technol.)
方向性を持った運動をするアメーバ型分子ロボットの開発
Toward vector motion of the cell-sized motorized molecular
Noriki Fukami1, Yuichi Hiratsuka2, Ibuki Kawamata1, Yuki Suzuki1,3, Satoshi Murata1,
Shin-ichiro Nomura1 (1Department of Robotics, Graduate School of Engineering, Tohoku University,
Sendai 980-8579, Japan., 2Japan Advanced Institute of Science and Technology, 3Frontier ResearchInstitute for Interdisciplinary Sciences, Tohoku University)
U. その他／U. Other topics

20558U20559U

20560U

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20562U20563U20564U20565U

Topological Data Analysis of Large-scale Multicellular Networks
Suguru Shimomura1, Satoru Iwasaki1, Tadashi Nakano2 (1Graduate School of Information Science andTechnology, Osaka University, 2Institute for Datability Science, Osaka University)
Observation of floating phenomenon of Cyclotella meneghiniana by direct microscope:
Temperature dependence analysis using a heater
Yuki Ide1, Yuji Matsukawa1, Daisuke Miyashiro1, Shigeki Mayama2, Matthew L. Julius3,
Kazuo Umemura1 (1Tokyo Univ. Sci., 2Tokyo Gakugei Univ., 3St. Cloud State Univ.)
矢が優れた飛び道具である理由ー自作風洞実験装置を用いた飛行する矢に働く力の分析ー
The reason why the arrow is superior flying tool - Analysis of forces acting on flying arrows byusing a home-made wind tunnel device Haruto Tgawa, Akito Wada, Hinata Furuya, Ayumu Yamamori (Osaka Pref. Tondabayashi H.S.)
一本鎖 DNA を被覆した単層カーボンナノチューブと細胞膜間の力学的相互作用
Mechanical interaction between single-strand DNA wrapped single-walled carbon nanotubes andcell membrane
Daisuke Miyashiro1,2, Ryo Hamano1, Kazuo Umemura1 (1Tokyo University of Science, 2ESTECH CORP.)
二本鎖 DNA とカルボキシメチルセルロースで分散した単層カーボンナノチューブの吸光度特性
Absorption properties of single-walled carbon nanotubes dispersed with double-stranded DNA
and carboxymethylcellulose
Ryo Hamano1, Daisuke Miyashiro1,2, Kazuo Umemura1 (1Tokyo Univ. Sci., 2ESTEC CORP.)
空気の抵抗が雷の発生と発光に及ぼす影響
Effect of air resistance on the generation and lightning of thunderbolt
Shingo Iwasaki (HatusibaTondabayasi H.S.)
基準振動解析を用いたロドプシンの動態予測と機能の連関
Relationship between function and dynamics of rhodopsin using normal mode analysis
Yukito Kaneshige1, Masashi Fujii1,2, Fumio Hayashi3, Kenichi Morigaki4, Hayato Yamashita5,
Akinori Awazu1,2 (1Dept. Math. Sci., Grad. Sch. Sci., Hiroshima Univ., 2Dept. Math. Sci., Grad. Integ. Sci.
Life, Hiroshima Univ., 3Grad. Sch. Sci., Kobe Univ., 4Biosignal Research Center, Kobe Univ., 5Grad. Sch.
Eng. Sci., Osaka Univ.)
Attempts at CA-type formal analysis of fibrous assembly of particles
Takashi Konno (Math. Biol. Med. Univ. Fukui)– S100 –20566U
20567U20568U20569U*

20570U

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Formation of small G-protein Ras multimer induced by chemical modification of HVR domain
Rufiat Nahar1, Maruta Shinsaku2 (1NAHAR RUFIAT, 2SHINSAKU MARUTA)
模型飛行機の主翼長が滑空性能に与える影響
The Effect of Wing Length on Gliding Performance of Model Airplanes
Fumiya Yamanaka (Osaka Pref. Tondabayashi H.S.)
円環気流接合殺菌法によるウイルス感染ルートの遮断
Blocking virus infection routes by CARS-sterilizattion
Kuniaki Nagayama1, Ryoichi Matsuda2 (1N-EM Labs., 2Grad. Sch. Sci., Tokyo Univ. Sci.)
Self-Assembly of Flexible DNA Ring Motif
Shiyun Liu1, Ibuki Kawamata1,2, Satoshi Murata1 (1Grad. Sch. Eng., Univ. Tohoku, 2Div. Natural Sci. Fac.
Core Research, Univ. Ochanomuzu)
分子スウォームの自動制御のための DNA 反応回路の最適化
Optimization of the molecular circuit for automatic controlling movement of microtubules
Daiki Matsumoto1, Ibuki Kawamata1, Yuki Suzuki1,2, Satoshi Murata1, Jakia Jannat Keya3,
Akira Kakugo3, Shin-ichiro Nomura1 (1Department of Robotics, Graduate School of Engineering, Tohoku
University, Japan, 2Creative Interdisciplinary Research Division,Frontier Research Institute forInterdisciplinary Sciences,Tohoku University, 3Department of Chemistry, Faculty of Science, Hokkaio
University)
機械学習を用いた生物形態の定量化とその応用
Characterization of biological morphology by using machine learning
Masato Tsutsumi1, Nen Saito1,2, Chikara Furusawa1,2,3 (1Dept. of Physics,Grad School of Science, The
Univ. of Tokyo, 2Universal Biology Institute, The Univ. of Tokyo, 3Center for Biosystems Dynamics
Research, RIKEN)
Circularization in coding regions of Flaviviruses are crucial for viral fitness
Roland G. Huber (A*STAR BII)

– S101 –