Anatomy
Schedule of First- and Second-Semester Major and Minor Subjects
Credits
Major subject: 6 credits per year
Minor subject: 1 credit per year
Supervising professors
Professor Shinichi Abe, Associate Professor Satoru Matsunaga, Senior Assistant Professor Masahito
Yamamoto, Assistant Professor Hidetomo Hirouchi
Educational objectives
To understand the structure of the human body, which is the basis of dental treatment; to develop
the ability to collect and analyze the information necessary for research in the field of anatomy; andto improve the ability to advance research by the acquisition of new research methods
Ⅰ．Principal research activity
To investigate the morphology and internal structure of the jawbone in dentulous and edentulous
jaws using micro-CT to facilitate nondestructive measurements of samples
Ⅱ．Departmental features
In addition to reviewing macroscopic anatomy, we also conduct comprehensive research using thelatest techniques in molecular biology.
Ⅲ．Department-specific curriculum
Advanced content related to clinical dentistry will be taught to graduate students during cadaveric
dissections.
Ⅳ．Objectives〇To explain the relationship between anatomy and other basic disciplines〇To explain the relationship between anatomy and clinical disciplines
Ⅴ．Methods〇Abstract-reading sessions will be held regularly to incorporate the latest research knowledge inother fields.
〇There will be active participation at clinical conferences where our research will be presented.

Ⅵ．Evaluation methods and criteria〇Students will undergo a comprehensive assessment related to the validity of experimental data,
will provide a summary of experimental results, and will participate in report writing, daily
observation records, and oral examinations.
〇Students will be required to submit their papers to international journals with high impact factors
for professional evaluation.
〇Passing grade: a minimum of 7 points each for post-tests, oral examinations, and reports
Ⅶ．Prospects after completion of graduate school〇We hope that our students will become clinicians with a solid foundation and knowledge ofanatomy and a commitment to continuous learning.
〇Only graduate students with excellent research abilities and who wish to conduct research atoverseas universities will be employed as researchers.
Lecture content
・Changes in jawbone morphology and nerve and blood vessel pathways associated with tooth loss
・The relationship between deciduous teeth roots, succeeding permanent teeth, and the surrounding
permanent teeth in the jawbones of children
・Mechanobiology of the jawbone using the multiscale method
・Cell biology underlying the mechanisms of muscle reactivation
・Creation of epithelial-mesenchymal hybrid cell sheets

Histology and Developmental Biology

Unit
Major subject 6 unit/year
Minor subject 1 unit/year

StaffsProfessor, Hitoshi Yamamoto
Senior Assistant Professor, Norio Kasahara
Senior Assistant Professor, Kei Kitamura

Educational goals
Students will sufficiently learn study methods of and knowledge about development,
growth, changes with aging, maintenance of homeostasis, and regeneration of structuresin the maxillofacial area including the teeth and periodontal tissue in the histology,
developmental biology, oral histology and developmental biology of the oral histology
fields and accurately understand the morphological characteristics and functions. In
addition, their ability of collecting information on new findings of the latest studies andobjective analytical ability will be cultivated as well as cultivation of their researchpromotion ability and research instruction ability.

I. Main study content
・Studies on development, growth, aging, maintenance of homeostasis, and regenerationof structures in the maxillofacial area including the teeth and periodontal tissue1

・Studies on ultrastructure of the teeth including crystal formation

II. Characteristics of the course
In the laboratory of this course, morphological studies are performed using various
types of light microscope and transmission and scanning electron microscopes, and at
the same time, the structures and functions are constantly investigated from biochemicalor physiological data. The study subjects are all structures in the maxillofacial area, anddevelopment, formation and growth, destruction, repair, and regeneration of these arecomprehensively investigated.
All full-time faculty members of this laboratory are concurrently in charge of the Schoolof Dentistry, but all of them are familiar with light microscopic and electron
microscopic research techniques including immunohistological/cytochemical study
methods and are experts able to sufficiently utilize these. In addition, the equipment
necessary to solve diverse subjects of the above studies is installed. Furthermore, joint
research with universities and research institutions in Japan and other countries areactively performed and persons wanting to study abroad are also managed.

III. Original curriculum of the courseFirst year: Students will select a theme from the research area described above anddesign a research plan to solve it. If a graduate student desires a certain theme, it will beprioritized. They will widely collect references regardless of those from Japan or othercountries to design a research plan and cultivate the ability to completely understandthese. They will participate in various related academic meetings including international
conferences and acquire the latest information. At the same time, they will learn lecture2and poster presentation methods. Furthermore, students will initiate learningtechnologies necessary to carry out research. They will also initiate preliminary
experiment.
Second year: Students will more completely learn technologies necessary to carry out
research and apply and develop these for their own study. Since characteristic andspecial methods are used in studies on hard tissue, such as teeth and bone, students will
understand the principles of the methods and practice these. Specifically, students willcomply various regulations and practice the methods, such as experimental animal
handling and human sample collection methods including unique sample preparation touse various types of light microscope, electron microscope, and other research facilities.
In addition, they will learn basic microscope operation methods and special application
methods. Furthermore, they will learn immunohistochemical and biochemical searchmethods as needed. Students will also initiate training as an educator throughparticipating in student practice from this year.
Third year: Students will collect and analyze data and present the study results inacademic meetings of related areas in Japan and other countries. If possible, they will
prepare and submit a doctoral dissertation for publication.
In addition, they will directly or indirectly instruct student practice to practice being an
educator.
Fourth year: Students will prepare, defend, and submit a doctoral dissertation. If
possible, they will summarize data not used in the doctoral dissertation into papers andsubmit these for publication. In addition, they will practice as an educator.

IV. Attainment goal
3

・The acquisition of basic knowledge necessary for a study in histology, developmental
biology, oral histology and the oral tissue development
・Acquirement of various histological and developmental research methods
・Collection of information about the new findings of the highest study
・Acquisition of the ability about histology and the developmental biology for education

V. Strategy
1) Passive methods: Lectures and practices2) Active methods: Experiments, sample preparations, microscopic examinations
3) Media: Various reference books and reports, participation in academic conferences

VI. Assessment method/criteria
Assessment method: Comprehensively assessed based on the validity of experimental
data, way of summarizing experimental results, report preparation, records of daily
observation, and oral examination.
Grading criteria: Oral examination and reports graded 6 or higher each will be regarded
as a pass.

VII. Prospects after completion of graduate schoolStudents will mainly become an educator or researcher (in Japan or other countries), butthey may become a clinician. Even if a student aims at becoming an educator or
researcher, he/she will practice being a clinician through gaining the cooperation ofpart-time instructors as needed.

4

講座名

Department of Physiology

特⾊Features of the course
To develop the ability to think logically, practice evidence-based medicine/dentistry and explain
physiological/biological responses or processes in clinical settings as well as to acquire the researchability in the broad fields of physiological sciences, postgraduate students will learn thephysiological mechanisms of sensory, motor and autonomic functions in not only the orofacial area
but also the organ systems by experiments- and classroom-based leanings and understand theregulatory mechanisms in maintenance of homeostasis of the whole body.

⼀般⽬標
To develop the ability to think logically, practice evidence-based medicine/dentistry and explain
physiological/biological responses or processes in clinical settings as well as to acquire the researchability in the broad fields of physiological sciences, postgraduate students will cultivate knowledge
in the orofacial/whole organ system physiology, various experimetal skills, presentation skills, paper
writing skills, information retrieval skills, skills in an information technology, internationality, andeducational skills, by classroom- and experiment-based learning.

⾏動⽬標Specific Behavioral Objectives
Postgraduate students will become to be able to acquire and explain followings;
1) To be able to acquire experimental skills,
2) To be able to acquire research skills for problem formulation and solving,3) To be able to collect and organize research information and to acquire the ability to objectively
analyze them,3) To be able to make presentations, write papers, and present research results in both Japaneseand English.
4) To acquire the ability to retrieve information for the research as well as for practicing evidencebased medicine/dentistry,5) To acquire the teaching ability for basic physiology to the undergraduate dental students,
6) To be able to explain mechanism of mechanical-electrochemical transduction in sensory
generation,7) To be able to explain transmembrane ion mechanism of tooth-forming cells (ameloblasts,
cementoblasts and odontoblasts) and bone cells,8) To be able to explain mechanism of functional expression of intracellular clock genes,9) To be able to explain pain receptive/integrative mechanism in the peripheral and central nervous
systems,
10) To be able to explain regulatory mechanisms in maintenance of homeostasis of the orofacial area
and whole body, and
11) To be able to play an active role in clinical practice as a dentist who is able to understands
biological phenomena scientifically and physiologically that occur in clinical settings in dentistry.
Learning Strategy0Evaluation

Pre and Post study

Text and Reference Book

Office hour

講義内容

Contents of lecture
Students will learn followings by lectures with or without experiments;
1. Mechano-electrochemical transduction mechanism of sensory receptor cells
1）Morphological characteristics of sensory receptors in the oral mucosa
2）Characteristics of mechano-sensitive ion channels in sensory receptor cells
2. Ionic mechanisms in tooth-forming cells
1）Characteristics of various ion channels2）Characteristics of intracellular second messenger signaling, and intercellular signalingmechanisms
3. Mechanism of saliva secretion
4. Functional expression of intracellular clock genes
5. Pain receptive and integrative mechanism in the nervous system
6. various experimental methods,
7. information retrieval skills
8. presentation, paper writing skills in both Japanese and English.
9. orofacial physiology
10. systemic physiology

■ S.mutans の分子遺伝学■ 幹細胞の機能解明とその癌の診断及び、治療への応用■ iPS 細胞、組織幹細胞維持機構の解明■ 組織再生におけるサイトカインの役割■ iPS 細胞と組織幹細胞の増殖分化・細胞死制御機構■ 「幹細胞の運命決定機構」の解明■ 癌と iPS 細胞、組織幹細胞■ 幹細胞の Epigenetics■ 疾患細胞由来 iPS 細胞を用いた疾患病態解明■ 遺伝子編集技術を用いた疾患細胞 iPS の正常化

■ Molecular genetics of S.mutans■ The function of tissue stem cell
■ The maintenance mechanism of tissue stem cell
■ Role of cytokines in tissue regeneration■

Proliferation and cell death mechanism of tissue stem
cells and iPS cells■ The fate determination mechanism of stem cell
■ iPS cells as a cancer stem cell, tissue stem cells■ The epigenetics of stem cell■

The understanding of disease mechanism by patients
derived iPS cells■

Normalization of patient derived iPS cell by gene
editing technology

Pathology
Lecture plan for major and minor subjects of the first and second semesters
Credit:Major subject, 6 credits/ year
Minor subject, 1 credit/ year
Person in charge
Professor: Kenichi Matsuzaka
Senior lecturer: Katsutoshi Kokubun
Assistant professor: Kei Nakajima
Assistant professor: Takatoshi Chujo
Assistant professor: Yoshihiko Akashi
Course objectives
1: To clarify the specificity of oral diseases in order to identify the diseasestate of oral diseases and to determine treatment plans.
2: To make dentistry successful, to clarify the wound healing mechanismof oral tissues and to discuss the reactions of biological tissues tobiomaterials.
3: To publish our research in international conferences and journals, tosearch for papers related to domestic and international research and to
explain the gist of these topics.

I. Main research content
1: The mechanism of invasion in oral cancer.
2: Pathogenesis-related factors in odontogenic tumors and salivary glandtumors.
3: Wound healing of teeth, tooth supporting tissues, and oral mucosa.
4: Biomaterials and tissue reactions.
5: Regeneration and reconstruction of teeth, tooth supporting tissues, andsalivary glands by tissue engineering.
II. Features of the Department
The purpose of our Department is to investigate the pathophysiology of oraldiseases from a morphological point of view by incorporating molecularbiology. These studies are extensive and wide-ranging, and are intended toenhance the ability of microstructural observations at the research level byperforming diagnosis of pathological specimens from the Suidobashi Hospital,
the Ciba Dental Center and so on. Discussions with academic advisors areheld as needed. A weekly progress briefing will interpret and examine thestudy data and set goals for the next week.
III. Original curriculum of the Department
1st year: Learn all techniques required for pathological and molecularstudies. Complete a paper on the contents (case reports, clinical reports, etc.)
presented by academic advisors. In the meantime, identify your pathologicalresearch topic of interest and start preliminary experiments.
2nd year: After the experimental protocol is designed, begin theexperiments and concentrate on data collection. The first report is presented
at a conference.
3rd year: Produce needed research data and prepare for thesis review.
4th year: Take the thesis examination and submit the thesis. Do theresearch and clinic that you choose.
IV. Course objectives
1: To understand the pathological features of oral diseases.
2: To guide research methods, considerations, and conclusions in line withresearch objectives.
V. Strategy
1: Diagnosis of pathology specimens requested by oral surgery
departments or other departments.
2: In vivo and in vitro experiments and research using pathology specimens
are performed according to the research theme.
VI. Evaluation system and standard
A passing score of 6 or more is given for each method used to compile theexperimental data, interpret the data, write the experimental notes, andcomprehensively evaluate the results through discussion (10-point method).

VII. Goals for the future
1: You can aim to be a university researcher.
2: It is possible to aim at becoming an oral cytology specialist dentist and/or
an oral pathology specialist.
3: You can aim to study abroad (our faculty members have studied at the
University of Oranda Nijmegen, the University of British Columbia,
Canada, and Harvard University).
4: You can become an evidence-based dental clinician.

Lesson content
1. Tooth and periodontal wound healing (regeneration and differentiation)1) Dental pulp cell kinetics and regeneration.
2) Periodontal ligament cell kinetics and regeneration.
3) Wound healing of oral mucosa.
2. Biomaterials and tissue reactions
1) Control of surface shape, properties and cell kinetics of biomaterials
3. Regeneration and reconstruction of oral tissues
1) 3D construction in vitro.
2) Construction of artificial oral tissue by tissue engineering.
3) Oral tissue regeneration by stem cell application.
4. Elucidation of the pathology of oral lesions
1) Oral mucosal disease.
2) Odontogenic disease.
3) Salivary gland disease.

講座名Department of Microbiology

特⾊Features of the course
Oral diseases such as periodontitis and dental caries are infectious disease caused by biofilm called
dental plaque. To clarity the etiology of these diseases, investigation of the biodilm in oral cavity
and immunoresponses againit the biofiom is essential. In this couse, investigation of the oral biofilm
and immunoresponses against the oral biofilm are carried out.

General Instructional objective

⼀般⽬標This couse aimed to investigate the mechanisms of biofilm formation focusing on the inter bacterial
communication by experiment using molecular biological technique and realize the pathogenicity ofdental plaque by literture review.

Specific Behavioral Objectives

⾏動⽬標1) Investigate the virulence of periodontopathic bacteria by molecular microbiological technique.
2) Investigate the immunoresponse against periodontipathi bacteria.
3) Investigate the effedt of oral bacteria on systemic disease.
4) Investigate the interbacterial communication.
5) Investigate the stress responses against environmental stress in oral bacteria.

Learning Strategy
1) Experiment2) Literature review

Evaluation
1) Monthly interview
2) Thesis paper

Pre and Post study
Read the papers associated with current experiments.

Text and Reference Book
Infection and Immunity
Journal of Bacteriology
Applied Environmental Microbiology
Clinical Microbiology
Office hour
Monday 16:00-19:00 Shin-kan 6F Laboratory of Microbiology

Contents of lecture

講義内容
1. Virulence factor of bacteria
2. Technique for molecula biology
3. Handling of bacteria
4. In silico analysis
5. Regulation in gene expression

Pharmacology
Lecture schedule for Major and Minor subjects (1st and 2nd semesters)

Course credit
Major subject
Minor subject

6 credits/year
1 credit /year

Instructors
Professor Masataka Kasahara
Assistant Professor Aki Takahashi
Assistant Professor Longqiang Yang
Assistant Professor Satoshi Yamamoto
1.

Education Goals (Diploma Policy)
1) Learn lab skills for biomedical research in the fields of cell biology, molecular biology and biochemistry etc.
2) Learn how to ask scientific questions and develop problem-solving strategies.
3) Learn scientific information retrieval skills and literature review.
4) Develop the global and interdisciplinary vision, and gain knowledge.
5) Develop critical thinking skills.

2.

Research Interests
1) Gene therapy of hypophosphatasia (Dr. Takahashi)
2) Development of biomaterials for dental tissue regeneration (Dr. Yang)
3) Analysis of exosomes from parotid gland saliva (Dr. Yamamoto)

3.

Course Features
1) Lab skills and techniques for a wide range of studies, e.g., animal experiments, cell biology, molecular biology,
chemical physics research, etc.
2) Studies focused on salivary glands, including the mechanism, therapy and drug development of drug-induced
xerostomia (dry mouth), pathology of xerostomia, development of saliva diagnostics.
3) Joint research with domestic/oversea universities and institutions, e.g., Nippon Medical University, Nippon
University Department of Pharmacology, Japan National Cancer Center, Sichuan University (China), etc.

4.

Curriculum for PhD program

1st grade:
1) Decide the research project for doctoral thesis2) Learn basic lab skills3) Learn research article reading skills4) Conduct literature review for the research project5) Prepare research proposal, preliminary study and data interpretation
2nd grade:
1) The same program as the 1st grade
2) Research progress report and presentation skills training at the lab and conferences
3) Conduct experiments and data interpretation
4) Conclude the research
3rd grade:
1) Research article manuscript preparation-13-2) Manuscript submission
4th grade:
1) Manuscript revision
2) Doctoral thesis defense
5.

Expected Outcome
1) Have critical thinking skills
2) Have problem-solving skills
3) Receive research training with global vision
4) Be able to apply pharmacological knowledge in clinical practice

6.

Strategy1) Learn critical thinking skills(1) Literature review and seminars(2) Research proposal preparation and presentation(3) Basic structure of research articles and academic writing
2) Learn problem-solving skills(1) Research proposal preparation, preliminary study and data interpretation.
(2) Research information retrieval and strategies(3) Research information collection and review
3) Train researcher with global vision(1) Attend oversea or international conferences and give oral/poster presentations(2) Have seminars with oversea researchers on scientific research
4) Know how to apply pharmacological knowledge in clinical practice(1) Give lab course and lecture to undergraduate students, and presentation at journal club.

7.

Evaluation
1) Comprehensive evaluation based on how to ask a scientific question, hypothesis development, research proposal
preparation, experiments conduction, data interpretation and analysis, preparation for new scientific questionand hypothesis.
2) Discussion of experiments data, progress report and presentation skills.

8.

Prospects
Develop critical thinking and problem-solving skills. To continue study at oversea institutions, and become a researchsupervisor at a university and institution. To become a clinician with good knowledge and skills for systematic healthmanagement and related medicine.

9.

Lectures
1. Function and roles of salivary glands
１）Mechanism of saliva secretion
２）Salivary glands and biological control system
３）Mechanism of xerostomia (dry mouth)
2. Roles of free radicals in dental pulp tissue１）Mechanism of free radicals２）Free radicals and anti-inflammatory drugs
３）Dental pulp cells and free radicals
４）Dental pulp blood vessels and free radicals-14-

3. Cancer cells and drug resistance１）Molecular biology of cancer drug resistance２）Studies to eliminate drug resistance
4. Clinical pharmacology
１）Drug interactions２）Evaluation of anti-inflammatory drugs and antibiotics used in oral surgery and periodontal disease３）Evaluation of drugs in dental anesthesia acting on the central nervous system and sympathetic nerves
４）Dental pulp and drugs
５）Therapeutic drug monitoring (TDM)-15-

Dental Materials Science
First and second semester main subject and sub-subject lecture schedule
Single main subject: 6 credits per year
Sub-subject: 1 credit per year
Masayuki Hattori (Professor), Masaaki Kasahara (Lecturer), Tomoko Someya (Lecturer)
1. Educational goals
To understand the basic knowledge of materials used in dentistry and instruments, understand theconnection with dentistry-specific technology in dental clinics, study the theory and application,and become a competent research instructor. (Diploma Policy: 1, 2, 3)
2. Main research contents
・ Evaluation of mechanical, physical, chemical and biological properties of dental materials
・ Basic examination for new dental material development
・ Development of titanium alloy and examination of titanium for clinical dental application
・ Evaluation of adhesiveness of tooth substance and restoration
・ Evaluation of fiber reinforced composite resin
・ Dental application of CAD/CAM
・ Elucidation of mechanical function of human mandible mainly by bone quality analysis
3. Features of the course
We are conducting research and development and evaluation for materials and instruments used in
dentistry, and along with improvement and development of materials and instruments actually usedin clinical practice, future dentistry such as CAD/CAM and biomechanics.
4. Course-specific curriculum
1) Measurement method of mechanical properties of dental materials, qualitative analysis by EPMA,
XRD, fatigue characteristic measurement method
2) Dental application of titanium3) Dental application of high-strength ceramics
4) Dental application of fiber reinforced resin, construction of abutment by FRC post
5) Cohesion and adhesion in dentistry6) CAD/CAM in dentistry
5. Attainment target
1) Measure the material properties with an universal tester and analyze the material with SEM, EPMA,
and XRD.
2) Create dental titanium and titanium alloys.
3) Evaluate the physical properties of high-strength ceramics such as zirconia.
4) Evaluate the construction of abutments using fiber-reinforced resin and FRC posts.
5) Evaluate the adhesive resin cement and bonding material.
6) Create dental materials that can be applied to CAD/CAM.
6. Strategy
Lectures, exercises, abstract reading sessions
7. Evaluation method/criteria
Comprehensive evaluation will be made based on the attendance rate of lectures and abstract reading
sessions, presentations at abstract reading sessions, and oral examinations.

8. Prospects after graduate school
After graduate school, there are many teachers who are active on the front lines of the dental world,such as practitioners, working doctors, university faculty and staff, and management of dental
material manufacturers, making use of their specialized knowledge and skills in materials andinstruments. Clinical reports are also published in dental magazines.
9. Lecture content items
For each item, check the latest technology using the Internet (30 minutes each time)
Physical characteristic test method for dental materials
1) Measurement method for mechanical properties
2) Qualitative analysis of dental restoration materials by EPMA and XRD3) Fatigue characteristic measurement method using a dental material fatigue tester
Dental application of titanium
1) Titanium characteristics and processing2) Titanium casting3) Reaction between titanium casting and buried material
Dental application of high-strength ceramics
1) Characteristics of dental zirconia
2) Processing of dental zirconia
Fiber reinforced resin and FRC post
1) Types of fiber materials
2) Fiber reinforcement theory and fiber post
Bonding and bonding in dentistry
1) Types of bonding materials and adhesives, bonding and bonding mechanisms
2) Adhesion with tooth substance and various dental materials
CAD/CAM and dentistry1) How to make a dental prosthesis device by CAD/CAM
2) Characteristics of CAD/CAM equipment

Department of Epidemiology and Public Health
前期・後期主科目および副科目講義計画表

単 位 主科目 年 6 単位
副科目 年 1 単位
担当者
杉原直樹 教授
石塚洋一 講師
Naoki Sugihara
Yoichi Ishizuka

佐藤涼一 講師
Ryouichi Sato

鈴木誠太郎 助教
Seitaro Suzuki

教育目標
Human resource development with the ability to contribute to the development of dental medicine
and the ability to conduct research and teaching at an international level by presenting new
knowledge to promote the maintenance and improvement of the health of the people, bothindividually (clinical) and in the community (community health).
Ⅰ．主な研究内容
1) Epidemiological research on oral diseases (dental caries, root caries, periodontal disease, dental
erosion) in adults and the elderly, and the development of prevention guidelines.
2) The relationship between oral diseases and lifestyle and oral environment in children and students.
3) Research on the percentile curve of present teeth
4) Oral health behavior in the life stages of Japanese people5) Development and evaluation of preventive technologies for oral health (including clinical trials)
6) Prevention of dental erosion and root caries by fluoride
7) Development of fluoride sustained release devices8) Analysis of clock gene expression in salivary glands
Ⅱ．講座の特色
1) To be able to learn epidemiological surveys and evaluation of the results (including statisticalanalysis) necessary for community health activities.
2) To be able to conduct epidemiological research on dental diseases.
3) In clinical dentistry, preventive measures to maintain and improve individual oral functions byassessing individual dental disease risks are becoming more important. To be able to researchmethods of assessing individual risk of dental disease and preventive measures.
4) The department is a certified training institution of the Japanese Society for Oral Health and a
specialist training institution of the Japanese Society of Gerodontology.
Ⅲ．講座独自のカリキュラム
1) Journal club for English textbooks or literature on standard preventive dentistry (or oral hygiene)2) Lectures and discussions on medical statistics for presentation at conferences and papers
3) Lecture and practice on medical statistical analysis using SAS and SPSS
Ⅳ．到達目標Dentists and researchers who have acquired the ability to promote the maintenance andimprovement of individual (clinical) and population (community health) health, and who have highcommunication skills to work internationally.
Ⅴ．方略
1) Lecture (oral hygiene and preventive dentistry)2) Demonstration (practice of statistical analysis using data obtained from community healthactivities)-18-3) Epidemiological survey (learning survey methods by participating in an epidemiological survey)
4) Practical experiment5) Discussion (discussion using research results)
6) Presentation at academic conferences
7) Writing papers
Ⅵ．評価方法・基準
1) Survey or experimental method and validity of data
2) Summary of experimental results3) Record of daily observations and oral examination
4) Report writing
Ⅶ．大学院修了後の展望
1) General practitioner
2) Employed dentists
3) Government (national and local governments)
4) Training institutions for dentists and dental hygienists (universities, junior colleges), others-19-Forensic Odontology and Forensic Anthropology
Professor : Masatsugu Hashimoto, Associate Professor : Noboru Ishikawa
Lecturor: Yasutaka Nakamura
Education Goals

Forensic odontology is a division of social dentistry whose ultimate purpose is to apply theknowledge of dentistry, inspect the evidence of the field of dentistry necessary for thejurisdiction, and make a proper evaluation. Therefore, education goals of Forensic Odontology
and Anthropology is to produce researchers who understand the purpose above described andcan carry it out.
Ⅰ Main Research Fields:
Forensic Odontological Fields:
1) Developments of the computer system for personal identification by the comparison ofante- and postmortem dental records and the examination of its effectiveness2) Establishment of the standard for age estimation of unknown body applicable to themodern Japanese
3) Studies on the analysis method of Bite mark evidence and its application to the actual
cases4) Establishment of the method for DNA extraction from very old teeth and bones
Forensic Anthropological Fields:
1) Consideration of the method for examination of the facial images observed on thephotographs/video
2) Establishment of personal identification method by morphological features of themaxillofacial regions
3) Consideration of new methos for personal identification from skeletal remains
4) Research on the estimation of time after death from dental point of view
Ⅱ Features of Department of Forensic Odontology and Anthropology
Forensic odontology and forensic anthropology focus on who criminal and victim are to
identify the body by utilizing dental and anatomical features. Other areas of activity include
appraisal of the mechanism of action of bite marks and injury to the dental area.
Furthermore, by learning various cases of trials, students will acquire high ethical standards,
humanity and cooperation as dentist.
Ⅲ Curriculum
Graduate students are able to conduct original research and participate in forensic
examinations. Therefore, even if you are a graduate student, you need to maintain strict
confidentiality. This course emphasizes the development of the ability to think for oneself andprogress things.
Ⅳ Attainment Target and Strategy
In the first year, in addition to acquiring basic knowledge and attending lectures, students
will plan their own experiments. In the second and third years, it will be started original
research and trained in report writing, presentation, and discussion of cases. In the final year,
students will compile their research results and prepare to publish them in an article.
Ⅴ Evaluation method and Criteria
Validity of experimental methods and results, quality of reports, and quality of papers will be
evaluated comprehensively.
Ⅵ Prospects after Graduate School
Priority will be given to the person's wishes.
The majority of graduates are active as clinicians. In some cases, the person will be hired asan educational staff member.
Contents of lectures:
Forensic Odontological Identification
Dental Identification
Bite Mark Examination and Personal Identification
Examination of Injures in Oral Region
Forensic Anthropological Identification
Facial Characteristics and Personal Identification
DNA polymorphysm and Personal Identification
Basic knowleges of General Genetics and DNA
DNA Polymorphysm and Data Analysis of Genetic Marker
Forensic Science and Law
Relationship between Forensic Science and Law
Forensic Science Examination and Law

歯 内 療 法 学
Department of Endodontics
前期・後期主科目および副科目講義計画表

単 位 主科目 年 6 単位
副科目 年 1 単位
担当者
古澤成博 教授
藤井理絵 講師 山田雅司 講師 佐古 亮 助教

田宮資己 助教

Educational goals
To develop the ability to confirm and diagnose basic matters related to tooth hard tissue
disease, pulp disease, and apical periodontal tissue disease. In addition, to acquire newresearch means necessary for these treatments, improve the ability to gather information, andcultivate research guidance ability that is familiar with both clinical and basic aspects.
Ⅰ. Main research contents
At this department, we have conducted biological evaluation of endodontic-related materials,
focusing on clinical pathological research.
As a future outlook, we wish to develop into new fields while making the best use of these assets. In
particular, molecular biology techniques are used to identify and correlate gene expression associatedwith treatment. In addition, the latest clinical technology will be verified and its evaluation will be
examined.
1)Pathology and diagnosis of pulpitis and apical periodontitis
2) Evaluation of periodontal ligament tissue protection and tooth transplantation / replantation
3) Cytokine therapy for bone defects in the endodontic area
4) Genetic diagnosis of bacteria in the root canal5) Drug discovery, verification and development of new technologies
II. Features of the course
Based on the fundamental policy that research results should be returned to clinical practice, many
drugs and materials developed from the research results of this department are still favored byclinicians. In the future, especially in terms of research, we would like to expand joint research withbasic laboratories rather than closed research on a course-by-course basis, and actively engage in
research that is beneficial to dentistry in general. However, the ultimate goal is to establish a newtreatment concept and method, and we would like to always keep in mind the return to clinical practice.

Ⅲ．Course-specific curriculum
Taking advantage of being a clinical course, it is possible for one to acquire various advanced clinicaltechniques in addition to research techniques. It is also possible to reflect research results andtechniques in actual clinical practice. (1) Mechanical root canal enlargement method and various root
canal filling methods, (2) Surgical endodontic treatment, (3) Treatment using a surgical microscope, etc.
It is also possible to acquire more advanced endodontics knowledge and skills through seminars
organized by the department.
Ⅳ．Attainment target
To acquire new research methods, improve the ability to gather information, and cultivate researchguidance ability familiar with basic and clinical aspects.
In addition, as a training facility accredited by the Japanese Society of Conservative of Dentistry and-22-

Japan Endodontic Association, training will be conducted with its own curriculum, with the ultimate
aim of acquiring certified doctor / instructor qualifications. Studying at graduate school gives you enoughtime to obtain these qualifications.
V. Strategy
Lectures, presentations, practical training

VI. Evaluation method / criteria
Comprehensive evaluation by oral examination and report writing regarding specialized areas.
Ⅶ．Prospects after graduate school
Those that have completed a course of graduate school not only lead the research side of thedepartment, but also play a central role in the clinical and educational aspects. We would like toprepare a post, as much as possible, where one can continue to play an active role as a leader inthe department.
Lecture contents
1. Diagnosis and pathology of pulp and apical periodontal disease
1) Pathology and diagnosis of pulpitis
2) Diagnosis of onset of apical periodontitis
3) Bone defect and X-ray diagnosis
2. The basics and clinical aspects of endodontic treatment materials
1) Pulp treatment materials and its reaction
2) Root canal filling materials and its reaction
3) Relationship between material composition and biological reaction
3. Acquiring basic research and techniques related to treatments related to the field of endodontics
1) Instruments for root canal treatment made of Ni-Ti
2) Imaging diagnosis using CBCT and establishing treatment policy
3) Endodontic treatment using a surgical microscope
4. Acquiring basic research and techniques related to surgical endodontic treatment
1) Protection of periodontal ligament tissue and tooth replantation / transplantation
2) Effect of barrier membrane on bone wound cavity
3) Retropreparation using retro-tip (ultrasonic tip)-23-

大学院生臨床研修プログラム

講座名

歯内療法学講座

主任教授名

古澤成博

プログラム責任者名（プログラムの管理・運営）

古澤成博

研修期間

３年間

受け入れ人数

８名まで

指導医

古澤成博

Program contents
1. Clinical cases necessary to obtain a certified doctor of the Japanese Society of Conservative
Dentistry
2. Clinical cases necessary to obtain a certified doctor of Japan Endodontic Association
3. Clinical cases, basic academic skills, and clinical techniques necessary to obtain a certified
doctor of Japanese Society of Oral Implantology
Specific application criteria to become academic society-certified doctors whose
requirements will be met at the end of the program
1. To obtain a certified doctor of the Japanese Society of Conservative Dentistry, it is necessary
to have a total of 6 years or more of academic membership history, submission of papers toacademic journals, academic presentations at academic societies, acquisition of training
credits, passing exams, etc. By finishing this program, with the subsequent training, therequirements will be fulfilled.
2. To obtain a certified doctor of the Japan Endodontic Association, it is necessary to have amembership history of 5 years or more, submission of papers to academic journals, academicpresentations at academic conference, aquisition of training credits, presentations of clinicalcases, and passing examinations. The requirements can be met in this program andsubsequent training.
3. In this program, the requirements can be met in the initial and subsequent training.

-24-

-25-

Periodontology
Objective
To develop abilities for data collection and analysis necessary for research and practice in thefield of periodontology. And to acquire abilities to conduct new research and implement novel
clinical practice.
Learning “Periodontology” aims to achieve “1. Present novel findings in the field”, “2. Possess
ability to contribute to the development of dental science”, and “3. Possess abilities to conduct andlead research in line with the international standard” in the Graduate School diploma policy.
Ⅰ．Research topics

1) Periodontal regeneration and its mechanisms
2) Tissue responses to dental implant3) Microbiological and immunological investigation of periodontal diseases
4) Periodontal medicine
II. Features of the department
1) Productive research group2) Acquiring advanced clinical skill
3) Program for the certified periodontist
III. Special activities
1) Literature review session
2) Case review meeting
3) Research progress meeting4) Lab meeting (in English)5) Instructions by clinical professors and visiting instructors
6) Hands-on courses on periodontal surgery
7) Joint meeting with Keio University School of Medicine
IV. Specific objective
Complete PhD thesis within 4 years
V. Learning strategies
1st year: Selection of research topic. Acquiring the basic experimental technique.
2nd year: Implementing experiments according to the research plan.
3rd year: Implementing experiments and presenting results at academic conferences.
4th year: Writing thesis paper and submission to an international journal
VI. Evaluation
1. Attendance (40%), Practice (60%)
2. Evaluation of lab notebooks, presentations and discussions at lab meetings
3. Evaluations at the thesis defense.
VII. Prospects after completion of the graduate program
1. Certification for periodontal specialist
2. Job opportunities in the college and hospitals
3. Research activities abroad

Operative Dentistry
Lecture plan for major and minor subjects of the first and second semesters
Credit:Major subject: 6 credits / year
Minor subject: 1 credit / year
Staff
Professor: Takashi Muramatsu
Associate professor: Hiroki Sugito
Senior Assistant professor: Akiko Haruyama
Senior Assistant professor: Hidenori Hamba
Assistant professor: Keiki Nakamura
Assistant professor: Keisuke Mitomo
Assistant professor: Sae Akehashi-Chikaraishi
Assistant professor: Hisako Ishizuka
Objectives
1. To understand the cause, diagnosis, and treatment of dental caries and non-cariogenic hardtissue diseases.
2. To master technique of operative dentistry treatment
3. To carry out research about material science, cariology and pulp biology
I．Main research contents
Considering "what is the restoration for?", The answer is "for the pulp." Therefore, in this course, we
are working on research on the three themes of "dental materials," "dental caries," and "pulp." In thecourse, we are engaged in research on the three themes of "dental materials," "dental caries," and"pulp." Establishing conservative and restoration treatment by studying the progression andremineralization of caries, and based on the study of the dentin-pulp complex, which is a defense
mechanism, and further researching adhesive materials to prevent secondary caries.
１）Development of new diagnostic methods and technologies for dental caries２）Application of micro-CT for dental research３）Mechanism of abfraction formation
４）Mechanism of suppressing demineralization and promoting remineralization of enamel
５）damage recovery system for dental treatment in dental pulp
６）Pulp stem cell differentiation, proliferation and potential for clinical application
７）Pathology and clinical application of pulp revascularization
８）Clinical application of dental laser device９）Color of restoration materials and dentin10）Adhesive mechanism of dentin / restoration material and its long-term stability11）Verification and development of drugs and new technologies
II. Features of the Department
Caries treatment is not merely removed, filled, and repaired, but is diagnosed after scientificexamination and analysis of the etiology and pathophysiology, and the treatment strategy isdetermined to be remineralization or filling and restorative treatment. After treatment, it is not theend, but the maintenance after that must be considered. Therefore, it is now called caries
management instead of caries treatment. This program is designed so that these viewpoints can be
grasped scientifically, and that training can provide feedback to clinical treatment.

III. Original curriculum of the Department
In this course, we understand basic caries treatment, cariology, dental material science, and pulp
biology. In addition to conservative treatment certified doctors and conservative treatment
specialists, there are staff that have certified doctors and specialists for oral and maxillofacial
surgery, periodontal treatment and pathology. You can learn a wide range of specialized clinicalpractice.

IV．Course object
1. To learn cariology, material science and pulp biology scientifically
2. To be a certified doctor by Japanese Society of Conservative Dentistry
V．Strategy
LecturePresentation
Practice
VI．Evaluation system and standard
1st grade:oral examination, case presentation and report
2nd grade:clinical practice
3rd grade:
examination of certified doctor
VII．Goals for the future
1. To be an independent doctor who directs research, education and clinical treatment.
2. To be an international doctor who collaborate about research, education and clinical treatment.
Lesson content
1．Caries examination
1) Bacterial examination
2) Laser examination
3) X-ray-free image examination
2. Treatment of dental caries
1) Remineralization therapy2) Operative dentistry treatment
3. Pulp biology and treatment
1) Response of dental pulp for dental treatment
2) Clinical application of dental pulp stem cell
4. Maintenance
1) Long term remineralization therapy
2) Prognosis of materials
3) Esthetic treatment
4) RepairPediatric Dentistry
The lecture plan for postgraduate students who choose pediatric dentistry
as the main or minor subject.

The number of credits
As the main subject: six credits per year
As the minor subject: one credit per year
Teaching staffs
Seikou Shintani, Professor.
Keiichiro Tsujino, Senior assistant professor.
Hiroki Imai, Senior assistant professor.
Atsuo Sakurai, Senior assistant professor.
Hiromi Homma, Senior assistant professor.
Yuki Arai, Assistant professor.
Ayano Nakauchi, Assistant professor.
Educational objectives
To cultivate the ability for accomplishment of original research containing new research methods inthe field of pediatric dentistry, we will teach the needed knowledge, philosophy, and skills.
Furthermore, for postgraduate students who choose pediatric dentistry as the main subject, they will
acquire more advanced knowledge and skills as pediatric dentists, and will cultivate the ability toteach younger students and dentists as an instructor.
I. Contents of the research
1) Morphological and functional research on the development of dentition and dental occlusion
2) Molecular study concerning the evolution of genes involved in tooth formation
3) Molecular biological study concerning aetiological factors which influence on the onset of congenitalabnormalities(1) Genetic analysis of aetiological factors associated with congenital abnormalities(2) The immuohistochemical study of factors associated with dental abnomalities
4) Epidemiological studies concerning oral diseases and oral health management in children5) An observation study of behavior control for children with disabilities at a dental facility6) Molecular study concerning oral bacteria associated with oral and systematic diseases.
II. Features of our department
Our department trains human resources who can carry out research on themes related to oral healthmanagement in childhood and trains clinicians who can practice oral health management for children.
Therefore, aims of our department are to acquire the knowledge and skills not only in pediatricdentistry but also in dentistry for children with disabilities through research activities and dailyclinical practice.
III. The characteristical curriculum for postgraduate students
The first and second year
1) In order to acquire a specialist certified by the Japanese Society of Pediatric Dentistry, postgraduate
students practice oral health management for children according to the training curriculum
established by the society.
2) Postgraduate students practice oral health management for children with disabilities according to
the training curriculum established by the Japanese Society for Disability and Oral Health..

- 31 -

The second, third, and fourth year
Postgraduate students create a research plan for the selected subject and conduct the research.
IV. The goals that should be accomplish are to1) Acquire the knowledge and skills necessary for research in the fields of pediatric dentistry anddentistry for children with disabilities
2) Be able to carry out original research.
3) Be able to practice more advanced dentistry for children and persons with disabilities.
4) Obtain the qualifications of specialists certified by the Japanese Society of Pediatric Dentistry andcertified doctors by the Japanese Society for Disability Dentistry.
V. Learning strategy
1) Lecture2) Journal club3) Academic meeting4) Dental practice5) Clinical conference6) Clinical and basic research in the fields of pediatric dentistry7) Regular meetings of research progress
VI. Evaluation items
1) Evaluation of the validity of research methods and interpretation of results by scrutinizing thenotebook that records the research content
2) Regular case presentations and oral examinations of pediatric patients that treated by postgraduate
students themselves3) Contents and completeness of presentations regarding clinical or basic research on pediatricdentistry at academic meeting4) Content and completeness of papers regarding clinical or basic research on pediatric dentistryVII. After the completion of graduate school
1) Graduates are mainly engaged in pediatric dentistry as specialists.
2) Graduates are engaged in dental practice for children with disabilities as certified dentists.
3) Graduates are enrolled in our department and continue to study their own themes.
4) Graduates qualify themselves for dental clinical instructor and teach younger dentists andundergraduate students.
Contents of lectures
1) The development of cranium, maxillofacial area, dentition, and dental occlusion in children(1) Methods of morphological and functional research on normal growth(2) Developmental abnormalities and their clinical evaluation methods
2) The development of teeth and developmental abnormalities(1) Clinical evaluation methods for tooth formation and dysplasia(2) Clinical evaluation methods for tooth eruption and abnormal eruption
3) Oral health management in children(1) Clinical evaluation methods for oral diseases and abnormalities in children(2) Prevention and treatment methods for dental caries and periodontal disease(3) Treatments methods for dental trauma and oral soft tissue diseases- 32 -

(4) Evaluation methods for the effectiveness of equipments used in pediatric dental practice4) Occlusal guidance(1) Examination and evaluation methods of dentition and dental occlusion(2) Various occlusal guidance methods(3) Evaluation methods for the effectiveness of equipments used for occulusal guidance5) Dental treatment for children with disabilities(1) Evaluation methods of oral health status and oral health management(2) Characteristic oral findings and dental treatment methods for each type of disability6) Diseases of infants and younger children(1) Oral findings and treatment methods- 33 -

- 34 -

Department of Oral and Maxillofacial Surgery
Main and Sub-subject lecture schedule
Main-subject : 6 unit / year
Sub-subject : 1 unit / year
Staff
Professor : Masayuki Takano
Senior Assistant Professor : Akira Watanabe, Takeshi Onda, Masato Narita,
Takamichi Morikawa
Assistant Professor : Shuji Yoshida, Keisuke Ohno, Hiroshi Kato, Ken-ichiro Shigeno,
Naoyuki Kogou, Takaharu Ariizumi
Educational objectives
We raise Surgion-scientist who have necessary Technology, Technique ,Information gathering ability, Information analysis ability for research and clinicalpractice on oral surgery, and have experienced both clinical medicine and basic
research.

Ⅰ. Main research contents










Basic and clinical environment on the treatment of malignant tumors in the
maxillofacial and oral region
Molecular biological analysis of oral cancer
Regenerative medicine with iPS
Research on wound healing and regenerative medicine
Research on jaw deformities
Research on reconstruction method after malignant tumor resection
Research on congenital anomalies such as cleft lip and palate
Research on maxillofacial deformity, temporomandibular joint disease, oral
maxillofacial implants
Basic and clinical environment on speech language

Ⅱ. Features of our department
Department of Oral and Maxillofacial surgery is responsible for the three primaryaxes of clinical environment, research, and education. However, in graduate school, as amatter of course, research is the most important item, but we think that it is indispensable
to learn the diagnosis, management, and treatment of basic oral surgery diseases as aclinical course. In addition, learning the basics of oral surgery clinical environment raises
questions through patients about what is lacking in the current clinical practice and how
to save patients' suffering, and it will also be a great motivation for research. And we areworking hard to return cutting-edge research and clinical environment for patients everyday.

Ⅲ. Our department curriculum
As an original curriculum, in the 1st year of graduate school, mainly outpatienttraining what you’ll learn the basics of oral surgery including tooth extraction. In the 2nd
and 3rd year, in hospital ward training what you’ll acquire basic matters as the major
surgical assistant for systemic management for pre- and post-operative patients. At thesame time, you’ll acquire skills that can apply the basic matters learned in the first year in
outpatient clinics.

Ⅳ. Achievement object for each year

1st
2nd
3rd
4th

(including clinical requirements, acquired techniques or qualifications): The minor surgery: Management of patients: The application of minor oral surgery and general management: The preparation of Thesis

Ⅴ. Strategy
Model training, clinical practice, training at other facilities

Ⅵ. Evaluation method / criteria
Oral presentations, journal presentations, and formative assessment
 Comprehensively evaluate the validity of experimental data, how to summarize
experimental results, report creation, etc., and daily observation records and oral
examinations.
 Post-test, oral examination, report: 6 points or more are passed.

Ⅶ. Prospects after graduate school
Resident of our department, dispatch to related hospitals

Ⅷ. Lecture contents
1. 1. Basic and clinical of oral cancer
1) Anatomy and metabolism of the oral mucosa
2) Mechanism of oral cancer
3) Histopathology of oral cancer
4) Treatment method for oral cancer and its evaluation
2. 2. Maxillofacial reconstructive surgery
1) Clinical anatomy and surgery necessary for maxillofacial reconstruction2) Microvascular surgery
3) Mandibular reconstructive surgery
4) Nerve reconstructive surgery5) Functional evaluation after reconstructive surgery
3. 3. Clinical application of biomaterials
1) Wound healing / regenerative medicine
2) Biomaterials in maxillofacial prosthesis
3) Histopathology of artificial tooth roots4) Biochemistry and histopathology of bone-forming proteins
4. Analysis, evaluation and treatment of maxillofacial morphology and dysfunction
1) Image diagnosis of jaw deformity
2) Treatment plan / treatment method for jaw deformity3) Functional evaluation after jaw orthodontic surgery (temporomandibular joint,
masticatory ability, nerve function)
5. Morphology / embryology of maxillofacial / oral region1) Elucidation and prevention of congenital anomalies, especially analysis of candidate
genes2) Mechanical analysis of mandibular morphology and mandibular defects
3) Analysis of maxillofacial morphology in jaw developmental abnormalities
4) Relationship with temporomandibular joint development, especially apoptosis
6. Exercise physiology of stomatognathic function
1) Functional evaluation for temporomandibular joint abnormalities
2) Functions before and after jaw orthodontic surgery3) Evaluation method for cleft palate language

4) Functional evaluation after reconstruction of the mandible
5) Study of speech by magnetoencephalogram
7. Clinical application of biomaterials
1) Biomaterials for recovery of stomatognathic function2) Mechanics related to biomaterial application in the stomatognathic functional area
8. Congenital anomalies such as cleft lip and palate
1) Cause
2) Diagnosis and treatment
3) Gene analysis

Department of Removable Prosthodontics and Gerodontology
Main subject and sub-subject lecture schedule in first and second semester
Credits Main subject 6 credits per year
Sub-subject 1 credit per year
Lecturers
Takayuki UEDA; Chief Professor, Masahiro RYU; Senior Assistant Professor, Tomofumi TAKANO;
Senior Assistant Professor, Midori OHTA; Assistant Professor, Yasuhiro HORIBE; Assistant Professor,
Akihiro ISHIDA; Assistant Professor, Takeshi SAITO; Assistant Professor
1. Educational goals(1) To acquire information gathering / organizing ability and logical thinking ability throughclinical research activities.
(2) To acquire evidence-based knowledge and techniques centered on prosthodontics andgerodontology.
(3) To be a specialist with a research mind and a global perspective.
2. Main research contents(1) Evaluation of materials for artificial teeth and denture bases, development of new technologies(2) Removable prosthesis treatment applying digital technology(3) Management and evaluation of removable prosthesis treatment(4) Evaluation of oral function and management of oral function in the elderly people(5) Evaluation of oral hygiene and oral hygiene management for the elderly people(6) Maxillofacial prosthetics/ prosthesis(7) Nutrition and oral function of the elderly people(8) Cognitive decline and oral function
3. Features of the course(1) We have a clinical training program linked to the required cases of application for certified
specialist of the Japan Prosthodontic Society and Japanese Society of Gerodontology. If you
complete the three-year course, you will be awarded a certificate of completion, and you will beable to meet the application qualifications of a specialist certified by the Japan Prosthodontic
Society and a specialist certified by the Japanese Society of Gerodontology. After that, if you
study for two years, you can obtain the specialists from each academic society.
(2) You can join the lecturers of this course and conduct out-of-hospital training where you canexperience dental care in various external environments different from the university hospital.
(3) You can join the daily morning meetings and the weekly journal club, which is reading sessions
to experience various research and clinical evidence.
4. Course-specific curriculum
In the research, we provide a journal club, small group discussions, and individual advice forthe goals.
In clinical practice, we provide lectures, case studies, small group discussions, and individual
advice for clinical practice.
5. Attainment targetIn order to play an active role in society, the ability to understand and evaluate domestic andforeign research related to the prosthodontics and gerodontology, the ability to guide and educate
students, and future prosthodontics and gerodontology, etc. Gain the ability to become a specialist.
First year: Acquire the ability to understand and present original articles in Japan and overseas.
Acquire the research planning method. Present the removable and fixed prosthetic
cases with the POMR method.
Second year: Make a research plan and conduct experiments. Learn statistical methods.
Presented at the Japan Prosthodontic Society and the Japanese Society of
Gerodontology. You will be able to plan highly specialized prosthetic treatments andhome visits.
Third year: Analyze the research results and make presentations at the Japan Prosthodontic
Society and the Japanese Society of Gerodontology.
Fourth year: Complete an original article in English. Submit to a highly acclaimed English
journal and make a final presentation at an international conference.
6. Strategy
In the research, abstracts and group discussions will be conducted under the supervision of thechief professor. In individual guidance, in addition to the chief professor, one or more academic
advisors are in charge of each student. In clinical practice, lectures, case studies, small group
discussions, and clinical practice are conducted. In clinical practice, an instructor is decided foreach case, and guidance is given according to the clinical training program.
7. Evaluation method / criteria
General goals, action goals, and evaluation criteria are prepared according to each curriculum.
The instructor uses it to evaluate it as an observation record.
8. Prospects after graduate school
One year after graduating from graduate school, you can try to apply for specialists such as theJapan Prosthodontic Society and the Japanese Society of Gerodontology.
9. Lecture contents
1) Examination of the oral functions in elderly patients and edentulous patients.
(1) Examination of edentulous patients.
(2) Diagnosis and examination of masticatory disorders, pronunciation disorders and aesthetic
disorders(3) Treatment planning for removable dentures and implant overdentures.
2) Rehabilitation with removable dentures(1) Removable denture and functional rehabilitations(2) Postoperative management of denture wearers(3) Evaluation of patient satisfaction
3) Diagnosis of functional disorders(1) Diagnosis of eating, swallowing and masticatory disorders(2) Diagnosis of pronunciation disorder(3) Diagnosis of aesthetic disorders(4) Diagnosis of jaw dysfunction4) Evaluation method of oral functions(1) Recording the EMG

(2) Recording the mandibular movement(3) Recording the occlusal contact state(4) Inspection of occlusal force distribution(5) Test of saliva production(6) Tongue function evaluation
5) Making an experimental plan
(1) Searching literature and using the literature database(2) Hypothesis planning and protocol creation(3) Data analysis method and statistical processing(4) Presentation technique and conference presentation method(5) Writing a scientific article in Japanese and English
6) Accumulation method of case presentations(1) Case photography method(2) Digital data management method(3) Personal information protection
Graduate Student Clinical Training Program
Course name

Department of Removable Prosthodontics and Gerodontology

Chief Professor Name

Prof. Takayuki UEDA

Program manager name(management/operation)

Prof. Takayuki UEDA

Training period

4 years from the 1st year

Number of people accepted

16

Instructors

Prof. Takayuki UEDA (Instructor of Japan Prosthodontic Society,
Instructor of Japanese Society of Gerodontology)
Dr. Masahiro RYU (Instructor of Japan Prosthodontic Society,
Instructor of Japanese Society of Gerodontology, Certified
Instructor of Sarcopenia and Frailty of Japanese Association on
Sarcopenia and Frailty, JSDR-Certified Clinician of theJapanese Society of Dysphagia Rehabilitation)
Dr. Tomofumi TAKANO (Specialist of Japan Prosthodontic
Society, Certified Doctor of Japanese Society of Gerodontology)
Dr. Midori OHTA
Dr. Yasuhiro HORIBE (Certified Doctor of Japanese Society of
Gerodontology, Certified Instructor of Sarcopenia and Frailty ofJapanese Association on Sarcopenia and Frailty)
Dr. Takeshi SAITO (Certified Doctor of the Japanese Society of
Gerodontology)
Dr. Akihiro ISHIDA (Certified Doctor of the Japanese Society of
Gerodontology)

Program contentsOur course is aimed to become a specialist who can provide advanced medical care centeredon prosthodontics and gerodontology to the public, and can educate junior dentists, dental
technicians, and dental hygienists. This course is an accredited training facility of the Japan
Prosthodontic Society and the Japanese Society of Gerodontology, and after completing thisprogram, it will be possible to acquire accredited doctors according to the regulations of eachsociety. After deciding on a doctor for each case, we will provide guidance according to the clinicaltraining program created by linking with the required cases of application for a specialist
certified by the Japan Prosthodontic Society and a specialist certified by the Japanese Society of
Gerodontology.
After you complete the course, you will receive a certificate of completion.
Specific application criteria for academic society-certified doctors who meet the qualification
requirements at the end of the program

The clinical training program of this course is characterized by being linked to the required
cases of applications for certified doctors of the Japan Prosthodontic Society and the JapaneseSociety of Gerodontology. After completing the 3-year clinical training course and submitting acase report, a certificate of completion will be awarded. Furthermore, the prepared case report
can be submitted as it is as application documents for the Japan Prosthodontic Society certified
specialist and the Japanese Society of Gerodontology certified specialist.
For specialists of the Japan Prosthodontic Society and specialists of the Japanese Society of
Gerodontology, it is necessary to have continuous membership history and training at a training
institution for at least 5 years. Therefore, in order to acquire a specialist of the Japan
Prosthodontic Society and a specialist of the Japanese Society of Gerodontology, it is necessary
to carry out one year of training as a clinical specialist course student or aresident after graduate
school.

Fixed Prosthodontics
Credit:Major subject, 6 credits/ year
Minor subject, 1 credit/ year
Person in charge
Professor: Hideshi Sekine
Associate Professor: Shuntaro Nomoto
Lecturer: Ryuichi Hisanaga
Lecturer: Mamoru Yotsuya
Assistant Professor: Takanori Sakai
Assistant Professor: Yu Tsuyuki
Assistant Professor: Takahiro Kawasaki
Assistant Professor: Shota Kuroda
Course objectives
1. To consider the solutions to disorders caused by tooth defect and tooth loss.
2. To clarify the characteristics of materials used for prosthetic treatment.
3. To present related research contents to domestic and international research
conferences and write research paper.
I. Main research contents
1. Prosthetic approach to the physiological function of the stomatognathic system
2. Harmony with the human body in the Fixed prosthesis
3. Response to stomatognathic dysfunction
4. Required properties of biomaterials in the fixed prosthodontics
II. Features of the Department
The purpose of this course is to investigate how to use a fixed prosthesis toeliminate aesthetic and dysfunction associated with dental diseases and maintaina recovered state for a long period of time. These studies are extensive and use aclinical approach to patients and volunteers and an experimental approach usingmaterials, models, animals, etc. If necessary, we will cooperate with basic andclinical researchers.
III. Original curriculum of the Department
1st year: Learn how to find research themes in prosthodontics. Complete the tasks(clinical report, basic research, research review) presented by the instructor. In themeantime, identify the prosthetic topics of interest and start a preliminary
experiment.
12nd year: Complete the research protocol based on the results of preliminary
experiments. We will consider the data processing of experimental results.
3rd year: Create the necessary research data and start writing a treatise.
4th year: Complete the treatise, undergo the treatise review, and submit the treatise.
IV. Course purpose
Understand prosthetic methods to resolve oral dysfunction. The purpose of theactivity is to solve unknown questions. Learn how to find and solve research
themes.
V. Strategy
Participate in the graduate school study group, collect information on research,and report on progress.
Participate in the abstract reading session to learn research methods,
understand the current situation of prosthetic questions, and understand related
papers.
Participate in related academic societies and seminars to improve yourknowledge and insight.
The experimental method is decided according to the research theme, and theexperimental results are derived.
The experimental results will be summarized in the paper and will pass theexamination.
VI. Evaluation system and standard
A passing score of 6 or more is given for each method used to compile theexperimental

data,interpret

the

data,

write

the

experimental

notes,

andcomprehensively evaluate the results through discussion (10-point method).
VII. Goals for the future
You can aim to become a university researcher.
It is possible to aim to become a specialist in dental prosthodontics inaccordance with the system accredited by a specialized society.
You can aim to study abroad (our faculty members studied at Boston University
and the University of Illinois in the United States).
You can be an evidence-based dentist.

Lecture content items (core subjects): Fixed Prosthodontics
1. Prosthodontic approach to physiology of the stomatognathic system21) Physiological mobility of natural teeth
2) Chewing function, pronunciation function3) Occlusal contact / translation
4) Three-dimensional analysis of mandibular movement
2. Harmony with the human body in the Fixed Prosthodontics
1) Research on mandibular movement control function2) Color studies in Fixed Prosthesis
3) Changes in dentition and occlusal relationship with aging
4) Research related fitness of fixed prosthesis
3. Digital Dentistry in Fixed Prosthodontics
1) Application of digital technology in prosthetic diagnosis
2) Clinical application of optical impression method
3) Manufacture of prosthesis with digital machining method
4. Responding of temporomandibular disorders (TDM)
1) Pathophysiology and etiology of temporomandibular disorders
2) Diagnosis and treatment of temporomandibular disorders
5. Research on biomaterial materials
1) Development of adhesive system in prosthetic area
2) Prosthetic supra structure of implant treatment
3) Intraoral adaptation of ceramic prosthesis
4) Application of hard resin to molars5) Adsorption of oral bacteria to prosthetic materials6) Basic research on clinical application of ceramic implant body3

Department of Removable Partial Prosthodontics

Shuichiro Yamashita (Chair Professor), Akinori Tasaka (Associate professor), Mariko Ohira(Assistant professor), Akihiro Tanaka (Assistant professor), Kazuhiro Ikeda (Assistantprofessor), Yoshimitsu Kato (Assistant professor)

Educational Objectives
To acquire the ability to carry out research in the field of prosthodontics and related fields,
as well as the ability to provide guidance to future generations, students will acquire theability to gather information, analyze, and present necessary for basic and clinical research.
In addition, we respect the acquisition of basic skills necessary for active self-study
attitude, logical thinking, and problem finding and solving.

Ⅰ．Main Research Activities
１）Research on the role of occlusion in stomatognathic functions２）Accuracy of removable partial denture framework fabricated by CAD/CAM technology.
３）Applying intraoral scanner to partially edentulous dentition
４）Study of an eating dysfunctions in the dependent elderly
５）Relationship between inclination of occlusal plane and jaw movements
６）Study on fatigue of removable partial denture

Ⅱ．Features of the Department
In order to be able to respond appropriately to various disorders caused by occlusal collapse,
it is necessary to objectively evaluate and understand the process leading up to the disorder.
In the case of partial tooth loss, many problems are intertwined in a complex manner over time
to cause the disorder. From this perspective, we are conducting research on the various topics
mentioned above.

Ⅲ．Department-specific CurriculumThis department's training program is designed to provide the training necessary to obtain
medical specialties from various academic societies, and the qualification requirements for
medical specialties from each academic society can be fulfilled in this program.

Ⅳ．Achievement of Goals
In order to acquire the ability to conduct research in the field of prosthodontics and related
fields and the ability to provide guidance to future generations, students will acquire theability to gather and analyze information necessary for basic and clinical research. In theend, students will complete a doctoral research paper, which will be published in aninternational journal.

Ⅴ．Learning Strategy

51

Conferences, Seminars, Self-study, Clinical study

Ⅵ．Evaluation Method and Criteria
Comprehensive evaluation will be made based on the validity of experimental data, summary ofexperimental results, presentation techniques, daily observation records, and oral
examinations. A score of 6.7 or higher in each section will be considered passing. If the levelof achievement in the oral examination is not sufficient, feedback will be given through areport.

Ⅶ．Prospects after Completing Graduate SchoolStudents will have the opportunity to further develop their research results in graduate
school, while at the same time improving their clinical and educational skills tocomprehensively diagnose and treat prosthetic cases.

Lecture contents
１．Methods for evaluating stomatognathic functions associated with missing teeth will be
discussed.
２．Evaluate the accuracy of removable partial denture framework fabricated by CAD/CAM
technology will be discussed.
３． Methods to improve the accuracy of intraoral scanning for partially edentulous dentition
will be discussed.
４． The diagnostic accuracy of the assessment method for dysphagia screening new system andthe actual survey of the eating and swallowing function of the dependent elderly in thefacility of the health care service will be discussed.
５．In determining the new the vertical dimension in occlusal and occlusal plane, theimportance to consider the most appropriate method for the patient's unique jaw and oral
system, rather than using average values will be discussed.
６．The discrepancies between clinical and academic practice in removable partial denture
design and the influence of using new materials and techniques in the fabrication of clasp
retainers will be discussed.

Graduate Student Clinical Training Program
Department

emovable Partial Prosthodontics

Chair Professor

Shuichiro Yamashita

Program Director

Shuichiro Yamashita

Training period

Three years

Number of students accepted

Up to 8 students

Medical advisor

Shuichiro Yamashita, Akinori Tasaka

52

Program Contents

The purpose of this program is to provide the training necessary to obtain medical
specialties from each professional society.
Specific application criteria for academic medical specialists who meet the eligibility
requirements upon completion of the programThis program can fulfill the qualification requirements for medical specialists of eachspecialty society.

53Orthodontics
Curriculum

Unit

Main subject 6unit/ySub-subject 1unit/yPerson in charge
Professor and chair Yasushi Nishii
Sinor assistant professor Haruyo Miyazaki, Kunihiko Nojima, Teruo Sakamoto, Hinorori Katada,
Takanobu Ishii, Chie Tachiki
Assistant professor Taiki Morikawa, Tomohiro Ebisawa, Yuki Iijima

教育目標
In accordance with the Graduate School Diploma Policy, discover new findings in orthodontics,
acquire the knowledge, skills, and attitudes that contribute to the development oforthodontics, and enable research guidance through research.
Ⅰ．Main research・Integration of 3D morphological analysis of maxillofacial morphology and orthodontic
diagnosis
・Masticatory muscle analysis of jaw deformity
・Evaluation of periodontal ligament response to orthodontic force
・Analysis of the reaction of osteoblasts and osteoclasts to orthodontic force
・Incidence analysis to mandibular condyle resorption
・Maxillofacial morphology analysis with AI
・Genetic analysis of jaw deformities

Ⅱ．Feature of Department
I．Through extensive research, medical care, and educational practices, we will develop researchon the morphology and function of the stomatognathic cavity from a highly specialized
standpoint from a biological basis. From general malocclusion to occlusal abnormalities,
jaw deformities, and congenital anomalies, the research results are returned to clinicalpractice, leading to the provision of high-quality medical care.
Ⅲ．Original curriculum
II．The three-year system, which is implemented as specialized clinical training after graduation,requires graduate students to take the course in parallel with research, and will acquire
the basics and clinical skills of orthodontics. After graduating from graduate school, it
can be used as part of the qualification to obtain a certified doctor of the Japanese
Orthodontic Society.
Ⅳ．Learning Attainment Targets
Freshman: Acquisition of basic knowledge and skills of orthodontics and extraction ofresearch subjects
Sophomore: Establishment of research method. Development of orthodontic clinical theory
and clinical skills
Junior: Conducting research, integrating correctional knowledge and technology
Senior: Summary of research results, presentation at academic conferences, submission of-57-

papers

Ⅴ．Strategy
・Lectures, practical training, clinical guidance (knowledge and skills of orthodontics) byclass teachers and all academic advisors
・Individual guidance by tutorials with your academic advisor
・Research progress presentation at graduate school debriefing session, group discussion on
its contents, and guidance by all academic advisors
Ⅵ．Evaluation method / criteria
・Paper test and submission of clinical trials (knowledge and skills of orthodontics)
・Evaluation of validity of experimental data, how to summarize experimental results, report
creation, etc.
する。
・Thesis evaluation
Ⅶ．Career after graduate school
Recommendations for residents and assistant professors

Lecture contents
１．Quantitative analysis of stomatognathic function
Muscle activity analysis by masticatory EMG and jaw movement analysis by nasohexagraph
Relationship between occlusal abnormalities and dysfunction
Relationship between measurement of expression pressure of perioral muscles in the dentition
and malocclusion due to habit
２．Computer-assisted orthodontics Morphological analysis / diagnostic skills
Dental morphology measurement with a three-dimensional dentition model
Surgical orthodontic treatment diagnosis support by 3D maxillofacial dentition morphology
model
Orthodontic evaluation of 3D soft tissue facial model

３．Application of 3D finite element method to orthodontic treatment
3D FEM analysis for the orthopedic treatment
3D FEM analysis of tooth movement dynamics by TAD

４．Aging of maxillofacial and dentition
Effects of orthodontic treatment and oral growth on oral health
3D morphological analysis of dentition stability
５．Congenital diseases / jaw deformities and orthodontic treatment
Classification and diagnosis / treatment of maxillofacial malformations / deformities
Diagnosis and treatment of occlusal abnormalities in bone system diseases and metabolic
diseases-58-

６．Cell biological analysis of tissue response to corrective and external force loads
Cell biological of tooth movement
Cell biological of bone response to external force-59-大学院生臨床研修プログラム

講座名歯科矯正学講座

主任教授名

西井康

プログラム責任者名（プログラムの管理・運営）

西井康

研修期間

４年間

受け入れ人数

3 名／年まで
西井 康、野嶋邦彦、坂本輝雄、立木千恵

指導医

宮崎晴代、片田英憲、石井武展

プログラムの内容
日本矯正歯科学会認定医研修機関（基本研修、臨床研修）としての研修を行う。3 年間の基本研修修了にあたっては、治験例 4 症例、保定観察症例 1 症例、論文 1 編を提出し、筆記試験と合わせ、合格の水準に達する事が必要である．
プログラム修了時に資格要件を満たす学会認定医等の具体的申請基準

認定条件は学会在籍期間が５年以上であること。学会の認めた研修機関で年間 1320 時間以上の修練を２年間、その後の研修期間または指導医常勤の医療機関における修練期間をあわせて５年以上が必要である。また、その間に 150 症例程度の臨床経験と論文が必要となる。
本プログラムは４年間の研修機関における修練実績として認定される。

-60-

Oral and Maxillofacial Radiology
Staff
Dr. Tazuko K. Goto, Professor and Chair
Dr. Mamoru Wakoh, Associate Professor
Dr. Mika Otonari-Yamamoto, Lecturer
Dr. Kento Odaka, Assistant Professor

Educational Curriculum
The core philosophy of the Graduate School here at Tokyo Dental College is one that focuseson the development of fully rounded individuals. Therefore, our most fundamental aim is tosupport and nurture young professionals, encouraging them to develop as broad a mind as
possible so that they will be able to play a role on both the domestic and international stage.
Every student will be expected to acquire a comprehensive knowledge of their field, not justthat of the oral cavity. Therefore, they will learn how oral medicine relates to the entire body,brain function, and pathology in general. Using the latest that technology and artificial
intelligence has to offer, they will also develop their ability to empathize with their patients.
In this way, our Graduate School programs aim to produce young dental professionals capableof serving the wider community.

1. Main Scope of Research
1) Oral Cavity and Brain Functiona) Relationship among the sense of taste, the brain, and the body as a whole(hypertension, diabetes, and so on). Imaging modality: Functional MRI.
b) Relationship between brain function and the oral and maxillofacial region (senseof taste, sense of smell, occlusion, pain, sports, psychology). Imaging modality:
Functional MRI.
c) Relationship between tooth loss and development of Alzheimer’s disease. Imaging
modality: PET.
2) Groundbreaking Developments in Diagnostic Imaging
3) 3-Dimensional Morphologya) Research into diseases of the jaw using 3-D printing. Imaging modality: CT andmicro-CT.
b) Diagnosis based on 3-dimensional morphology. Imaging modality: MRI and CT.
4) Clinical Case Studiesa) Relationship among diagnostic imaging and clinical and pathological findings.
Imaging modality: MRI, US, CT, plain radiography, etc.

2. Global and Liberal Arts: Special features of this department
All our staff are dedicated to fostering the widest possible outlook in our Graduate School
students. Each and every one has a rich background of experience in dental medicine on both
the domestic and international stage. One of our aims is to bring our experience as human-60-beings, not just medical professionals, to bear in our work here. Therefore, all our students
are encouraged to select the direction that best suits their needs as an individual in terms ofresearch content, level, and future ambitions. We provide a welcoming research environment,with a male-to-female ratio of one-to-one. It is in this setting that each student will be given
free rein to develop and pursue their own goals.
1) This department provides the kind of work environment that might be found at a
general university overseas. We collaborate with specialists from a wide range ofbackgrounds encompassing, science, engineering, the liberal arts, and more. We also
enjoy a strong relationship with the world of business.
2) Each student will also be enthusiastically encouraged to grow as a clinician. As such,they will be expected to hone not only their skills in diagnostic imaging, but also in thevarious practical aspects of dentistry in a clinical setting.

3. Unique Aspects of Departmental Curricula
1) Researcha) Students will have access to individual instruction at any time.
b) Students will be able to attend weekly research meetings. They will be
encouraged to freely discuss their work, particularly with regard to how it isprogressing, and share information.
c) Students will also be able to attend monthly departmental meetings to discuss
their work, at which they will be given feedback and assessment on how they
are progressing.
2) Clinical Practicea) Students will be able to discuss cases encountered the previous day at morning
conferences.
b) Students will master the fundamentals of clinical medicine in weekly
conferences, clinical practice sessions, and clinical study meetings.
c) Students will acquire a high level of diagnostic ability through attending
weekly conferences on cases of particular interest.
d) Students will acquire certification as oral and maxillofacial radiologist from theJapanese Society for Oral and Maxillofacial Radiology.

4.

Yearly Goals

1st year: Submit ethical clearance applications for research; gathering of information byreading the relevant literature; development of a research plan; commencement ofresearch project.
2nd year: Continuance of research work; giving presentations at domestic academic
conferences.
3rd year: Continuance of research work: preparation of paper, presentation at international-61-

academic conferences; taking of examination for certification as oral and maxillofacial
radiologist.
4th year: Submittance of paper for publication in academic journal; taking of examination
for Doctor of Philosophy; preparation for study overseas.

5.

Teaching Methods
Research meetings, conferences, seminars, lectures, etc.

6.

Assessment and Standards
Assessment will be based on the results obtained in relation to each educational goal to beachieved. A minimum of 70% will be required to obtain a pass.

7.

Post-Graduation Support
1) After graduating on completion of the 4-year course, the students will be able to receive
support in attaining their career goals, whatever their chosen path, whether it be as auniversity-level educator, diagnostic clinician, public servant, dental practitioner, orother.
2) On completion of the course, the students will also be able to aim for further
qualifications, including as a Certified Specialist/Senior Specialist (supervisory doctor)
for Oral and Maxillofacial Radiology, Certified Specialist/Senior Specialist (supervisory
doctor for the Temporomandibular Joint, Specialist in PET, and Specialist in
Malignant Tumors in the Oral Cavity.
*Qualification as a Specialist of Oral and Maxillofacial Radiology indicates eligibility
to advertise under the regulations of the Ministry of Health, Labor and Welfare.

Lecture Contents
Diagnostic Imaging, Anatomy, Neurophysiology, Statistics, General Dentistry, etc.

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-63-

Dental Anesthesiology
Curriculum for main major and sub-major during first and second semesters
Units Main major
6 units per year
Sub-major 1 unit per year
Faculty members
Professor: Tatsuya Ichinohe
Senior Assistant Professor: Toshiyuki Handa, Kyotarou Koshika
Assistant Professor: Jun Kawaguchi, Hirokazu Kukidome, Kaori Yoshida, Ayano Hagiwara,
Kaori Takahashi
Learning objectives
To learn fundamental ability to promote and lead scientific researches through obtaining researchcompetencies on ideas, skills and information collection and analysis, and to achieve new knowledge inthe field of dental anesthesiology.
Ⅰ. Main research subjects
1) Local anesthesia(1) Respiratory and hemodynamic effects of vasoconstrictors contained in local anesthetic solution(2) Effects of vasoconstrictors contained in local anesthetic solution on dental pulp
(3) Evaluation of local anesthetic effect2) Systemic management of dental patients(1) Hemodynamic stability during general anesthesia(2) General anesthesia and tissue blood flow/tissue oxygenation(3) Intravenous sedation(4) Monitoring equipment(5) Geriatric, medially compromised and disabled patients
3) Pain clinic(1) Treatment of chronic pain(2) Management of postoperative pain
Ⅱ. Characteristics of the department
1) Graduate students select research subjects required for practicing “safe, comfortable andpain-free dentistry”. Thus, research products will be available for near-future clinical activities.
2) Graduate students receive clinical training till the first semester of second grade and then they go
into research life in third and fourth grade.
Ⅲ. Unique curriculum of the department
1) Medical anesthesia training during first or second grade
2) Case report on the Journal of Japanese Dental Society of Anesthesiology3) Qualification of the Japanese Board of Dental Anesthesiology during graduate student
Ⅳ. Learning objectives
1) First and second grade: To learn basic knowledge and clinical skills on dental anesthesiology andpublication of a case report
2) Third and fourth grade: To conduct research and complete thesis, and be qualified as the Japanese
Board of Dental Anesthesiology
Ⅴ. Learning strategies
1) Knowledge: Lectures, presentation at the department meeting, participation in academic- 64 -

meetings, and publication of scientific articles
2) Skills: Clinical training and practices using simulators
3) Research: Experiment, presentation at academic meetings and publication of scientific articles
Ⅵ. Evaluation
1) Knowledge: Oral examination and report submission2) Skills: Clinical experiences and skill check3) Research: Research ethics, level of understanding, presentation ability and writing talent4) Activeness as a graduate student
Comprehensively evaluated as follows;
A: Excellent, B: Good, C: Satisfactory, D: Unsatisfactory
Ⅶ. Carrier path after graduation
They can receive medical anesthesia training for 1 – 2 years and be qualified as a Board Certified
Dental Anesthesiology Specialist. After that, they will be;1) Faculty member of a dental anesthesiology department
2) Dental anesthesiologist in a general hospital3) Dental anesthesiologist in a local dental center for disabled patients
Lecture contents
Each item requires 1 - 2 hours review and self-study on relative issues after lecture.
1) Local anesthesia(1) Respiratory and hemodynamic effects of vasoconstrictors contained in local anesthetic solution(2) Effects of vasoconstrictors contained in local anesthetic solution on dental pulp
(3) Evaluation of local anesthetic effect2) Systemic management of dental patients(1) Hemodynamic stability during general anesthesia(2) General anesthesia and tissue blood flow/tissue oxygenation(3) Intravenous sedation(4) Monitoring equipment(5) Geriatric, medially compromised and disabled patients
3) Pain clinic(1) Treatment of chronic pain(2) Management of postoperative pain4) Medical statistics(1) Medical statistics- 65 -

Clinical training program
Department

Dental Anesthesiology

Chair

Professor Tatsuya Ichinohe

Person in charge

Professor Tatsuya Ichinohe

Training length

4 years

Maximum students

16

Instructors

Tatsuya Ichinohe, Toshiyuki Handa, Kyotarou Koshika,
Jun Kawaguchi, Hirokazu Kukidome, Kaori Yoshida,
Ayano Hagiwara, Kaori Takahashi

Contents
Clinical training for qualification of the Japanese Board of Dental Anesthesiology and Board ofJapanese Society for Disability and Oral Health.
A total of 1000 general anesthesia cases, 7000 of intravenous sedation cases and 1500 pain clinic
cases are given in Suidobashi Hospital and Chiba Dental Center.
Medical anesthesia training during first or second grade.
Requirements for qualification
Japanese Board of Dental Anesthesiology
1) 2 years membership or more
2) 200 general anesthesia cases3) 50 intravenous sedation cases4) 1 publication on the Journal of Japanese Board of Dental Anesthesiology
Japanese Board of Dental Anesthesiology
1) 3 years membership or more
2) 60 systemic management cases for 20 patients
3) 1 presentation in an annual meeting of Japanese Board of Dental Anesthesiology- 66 -

Oral Health and Clinical Science
Unit) Main subject six units/year
Sub-subject one unit/year
Instructor)
・Prof. Ken-ichi Fukuda, Associate Prof. Yumi Otawa
Assistant Prof. Atsushi Hanzawa, Assistant Prof. Tomoyasu Noguchi
・Prof. Ryo Ichida , Associate Prof. Mai Okubo
・Prof. Tomotaka Takeda, Associate Prof. Kazunori Nakajima
Educational goals)
Accumulate and practice as a clinician.
Acquire information gathering ability and analytical ability necessary for basic and clinicalresearch in each field.
Acquire the ability to carry out research and the ability to teach younger students.
Ⅰ．Contents【Division of Special needs dentistry and Orofacial Pain】
1) Analysis of oxygen supply and demand and heart rate variability of the masticatory muscles
during bruxism and physical therapy2) Pain-related gene polymorphism analysis related to orofacial pain onset vulnerability
3) Nerve MRI image analysis for local pathophysiology of orofacial neurosensory damage
4) Orofacial region Imaging of central nervous system function of chronic pain
5) Relationship between glossodynia onset factors and potential developmental disorders
6) Analysis of pathological conditions of dental patients with special needs and devising behavior
therapy【Division of Dysphagia Rehabilitation】
1)Determination of the Relationships Tongue Hardness, Thickness, and Pressure Using
Ultrasonic Elastography2)Development of a method to visualize and evaluate changes in eating motivation
3)Development of a new eating and swallowing function questionnaire including self-awarenessand coping ability4)Search for the relationship between swallowing function and oxidative stress in the elderly5)Sensory Processing Issues with Feeding Problems6)Investigation of the swallowing function and chlorpromazine equivalent dose of antipsychotic
drugs in patients with psychiatric disorders
7)Effect of Neuromuscular Electrical Stimulation on Masseter Muscle Thickness and Maximal
Bite Force among Healthy Persons8)Exploring the relationship between knowledge about oral function and oral functional status【Division of Sports dentistry】
1) Effect of stomatognathic condition on systemic athletic performance2) Effect of stomatognathic condition on equilibrium function
3) Effect of stomatognathic condition on brain activity
4) Research on the expression of masticatory muscle activity during sports and physical exercise
5) Effect of sports clenching and mouthguard on stomatognathic trauma
6) Effect of sports clenching and mouthguard on concussion-67-7) New development of mouthguard material8) Effect of gum chewing on brain activity9) Effects of gum chewing on stress reduction10) Epidemiological study on stomatognathic sports trauma11) Study on the effect of oral device for sleep apnea treatment
Ⅱ．Features
This course was established in April 2015 by integrating three laboratories: Special needs
dentistry and Orofacial Pain, Dysphagia Rehabilitation, and Sports Dentistry. Based on theabundant clinical cases of Suidobashi Hospital, this clinical course focuses on research activities
aimed at improving the oral quality of life of patients. This is a new type of complex course that
conducts clinical, research, and educational activities in units of one oral cavity, rather thanspecializing in a specific field.

Ⅲ．Curriculum
The clinical training program of this course aims to provide training necessary for acquiringcertified (specialized) doctors of academic societies in each field, and this program must satisfy thequalification requirements of certified (specialized) doctors of each specialized academic society.
Ⅳ．Attainment target
By studying as a clinician, students will acquire the information gathering ability and analyticalability necessary for basic and clinical research in each field, which will eventually lead to thecompletion of their dissertation. The treatise at the time of completion will be published in theinternational journal.

Ⅴ．Strategy
Conference, English journal reading session, clinical training

Ⅵ．Evaluation method / criteria
Comprehensive evaluation will be made based on the validity of experimental data, how tosummarize experimental results, presentation techniques, daily observation records, and oral
examinations. Each pass is 6.7 points or more.

Ⅶ．Prospects after graduate school
It is possible to have the ability to comprehensively diagnose, formulate a treatment policy, andtreat while making use of clinical research in each field as one oral unit, not by dental disease.
Lecture content items
1. Orofacial Pain Relief and related pathophysiology
2. Behavior therapy for patients with special needs and related pathology
3. Dysphagia rehabilitation and related pathophysiology
4. Prevention of sports injuries and related occlusal studies-68-Oral Implantology
First and second semester, main subject and sub-subject lecture schedule
Credits: Main subject
6 credits/year
Sub-subject
1 credit/year
In charges:
Prof. Yasutomo Yajima, Assoc. Prof. Taichi Ito, Lecturer. Yoshitaka Furuya,
Lecturer. Hodaka Sasaki, Assis. Prof. Tomoki Hirano, and Assis. Prof. Yukari Oda
Educational goals
To understand the importance of basic research by learning implantology, a comprehensive
multidisciplinary field, in order to become a dentist who can practice evidence-based clinicaldentistry.
To become aware of ethical issues as a scientist; develop presentation skills (oral presentation
and writing ability); and develop an understanding of how to gather data, perform research, andanalyze the data correctly.

Ⅰ．Main goals of a research program
1. Improve the success rate of implants (development of new materials, implant systems, andimplant designs, along with elucidation of mechanical mechanisms).
2. Expansion of indications for implants (mechanisms and prognoses of various bone augmentation
methods as well as management of soft tissues).
3. Shorten the healing period (immediate loading, early loading, and immediate implant placement
after tooth extraction; healing mechanisms with immediate loading).
4. Pursuit of aesthetics (changes in peri-implant tissue, relationship between implants andperiodontal bacteria).
5. Medical safety (development of navigation systems; development of educational programs).
Ⅱ．Features of the department
The Department of Oral and Maxillofacial Implantology is the newest department in Tokyo Dental
College, which was established in 2009. New departments have great advantages, such as a newresearch system with a novel viewpoint not bound by old customs. In addition, as few universities
have a department of implantology, our department will be at the forefront of implantology research.
We would like to feature this department as a “base for disseminating information on implantology
to the world”.
Ⅲ．Specific goals of the curriculum
1st year: To learn clinical practice methods and understand the logical thinking and procedureof initiating a paper and completing a paper (case report, medical statistics), which
will be guided by the instructor. Additionally, clinical practice will help develop
problem solving skills using one's own information gathering and analytical ability.
2nd year: To discuss the research you are interested in with your instructor, you will need tocreate a protocol, and conduct a pilot experiment. To collect data for the final
experiment, additional experiments will be performed and the protocol will be modified
accordingly.
rd
3 year: To give a presentation on your own experiment at an academic conference and complete
a paper for publication after finalizing data analysis.
th
4 year: To submit a paper and instruct undergraduate students on experiments that they will-70-

perform with the instructor. In addition, you will perform clinical practice similar tothat of scientists and perform research on new themes.
Ⅳ．Archiving goals
１．To acquire evidence on implant treatments and develop a successful treatment plan.
２．To receive credits for certification as a doctor recognized by the Japanese Society of Oral
Implantology and Japanese Academy of Maxillofacial Implants.
Ⅴ． Strategy
・Write a clinical paper ・Give a presentation at an academic conference ・Give a presentation
at a clinical meeting ・Attend a seminar ・Attend journal club
Ⅵ．Evaluation and Standards
・Evaluation of clinical observation records ・Evaluation of a step-up test in accordance withimplant guidelines ・Comprehensive evaluation by reviewing a paper that you wrote.
Ⅶ．Possibilities after the graduate course
It is possible to be an assistant professor or resident in the department of oral and maxillofacial
implantology. In addition, it is possible to study abroad（Federal Republic of Germany: Göttingen
University, Friedrich-Alexander University Erlangen-Nürnberg, Hannover Medical School).

Lecture Content
１．General outline in oral implantology１）Specificity in dental implant treatment
２）Flow of dental implant treatment and future implantology３）Biological reactions of implants to tissue interfaces４）Surface chemistry and surface topography of implant materials
２．Special topics in dental implantology１）Treatment planning and indications
２）Implant placement surgery３）Complications４）Superstructure５）Maintenance
３．The relation between implantology and basic dentistry
４．The relation between implantology and clinical dentistry
５．Current status and future prospects of regenerative medicine in implantology
６．Practicum
１）Anatomy for implant treatment２）Implant placement for a dental model-71-

Clinical Training Program for Graduate Students

Department name

Department of Oral and Maxillofacial Implantology

Chief professor name

Yasutomo Yajima

Person inprogramchargeoftheYasutomo Yajima

Training period

4 years

Accepted number of students

Up to 20 students

Instructors

Yasutomo Yajima, Todshikazu Iijima, Tatsuo Shiigai, and Takayuki
TakedaContents of program
Chiba Dental Center: training on implant treatment in the Implant Department of the college
and completion of a clinical paper.
Private clinic of clinical professors: training on implant treatment in the private clinic.
Specific application criteria that meet eligibility requirements at the end of the program (e.g.,
certified doctors by an academic society)
The application criteria for a certification as a doctor by the Japanese Society of Oral
Implantology are as follows: enrollment in a training facility for a total of 5 years or more,
completion of training, a presentation at an academic conference, and a publication in ajournal. At the end of this program, most criteria will be met other than years of enrollment.
It is also possible to carry out a curriculum that matches being a certified doctor of theJapanese Society of Maxillofacial Implants.

-72-

Department of Oral Oncology, Oral and Maxillofacial Surgery
Adquisition Unit Requirements

Major subject (Oral aObjec Maxillofacial Surgery): 6 credits per year (minimum 24 Credits tograduate) or more
Sub-subjects (Optional): 1 credit per year (minimum 4 Credits to graduate)
Specialized Lectures: 2 credits per year (minimum 4 Credits to graduate)
Seminars: 1 credit per year (tminimum 3 Credits to graduate)
Academic stuff/ Instructor’s Information
Takeshi Nomura (Chief Professor/Academic advisor/Mentor)
Hirokazu Saito (Assistant Professor)
Kinue Kurihara (Assistant Professor)
Daiki Suzuki (Assistant Professor/Oral cancer program coordinator)
Masaki Minabe (Assistant Professor)
I.

Graduate Program Objectives and Student Learning Outcomes
Based on the diploma policy of the Graduate School of Dentistry at Tokyo Dental College, ourdepartment offers research oriented educational program in the field of oral and maxillofacial
surgery and oral oncology that fosters expertise and enhances critical thinking in students bydeveloping comprehensive and multiple points of view; cherishes international diversity; andpromotes for students’ career paths.

II. Research Subjects
1. Oral cancer
1) Development of diagnostic study for the Oral potentially malignant disorders (OPMDs)
2) Exosome analysis in saliva will be taken from patients with oral squamous cell carcinoma
3) Characterization of O-glycans of mucins extracted from mucoepidermoid carcinoma
4) Elucidation of the mechanism of epithelial mesenchymal transition (EMT) in oral squamous cell
carcinoma
2．Oral complications resulting from systemic disease1) Diagnosis and treatment of autoimmune blistering disease in oral mucosa
2) Effect of bacterial infection on bone quality and structure in medication related osteonecrosis of thejaw3) Gene panel testing for Gorlin syndrome4) Oral microbiota in the patients of palmoplantar pustulosis
III. Characteristics of our department
The work place is located at Ichikawa General Hospital, Tokyo Dental College in Chiba prefecture.
Our department involves the division of Oral Medicine, Oral and Maxillofacial Surgery. Throughmedical and dental collaboration, the department also provide specialized medical care for diseases
related to oral cavity. Additionally, oral cancer center was established in 2006 and have agreements
in various hospitals. Furthermore, we provide advanced oral cancer treatment in cooperation witheach of the concerned department which consists of oral and maxillofacial surgeon, plastic surgery,head and neck radiology, maxillofacial prosthetics and oral rehabilitation team. We provide diagnostic
procedures and treatment techniques for oral cancer to undergraduate dental students, as well aspractical surgical techniques for oral cancer to graduate dental students. Furthermore, we boost thesurgical treatment not only oral cancer but also oral and maxillofacial disease such as jaw deformity,-1-

cleft lip and palate as physician scientists. Through highly advanced medical treatment, our teamchallenge the innovative translational research.

IV. Curriculum overview:First-Year: The student participation in the treatment of outpatient and inpatient medical care will
be done at Ichikawa General Hospital. Especially, learning about clinical practice in the treatment oforal cancer patients will be done at oral cancer center. In order to increase individual chances ofsuccess, the candidate will be assigned the specific professors in the area of research such as physician
scientists through clinical practice.
From 2nd – 4th Year: Each candidates decides on a research theme and start the life in academia. Our
department is held monthly meeting and whole students taken an active part in the discussion foreach research. Furthermore, we hold monthly journal clubs and participate in academic activities.
The students (candidates) will be able to participate in several annual meetings abroad such as theOral and Maxillofacial Surgery Congress. The article should be completed in four years and thestudents have a degree once be done thesis defense.
Case Material
An adequate volume and diversity of clinical exposure is available to provide a complete and effective
educational experience. This includes an appropriate number of cases in the following areas: Facial
trauma surgery, Orthognathic surgery, Temporomadibular joint surgery, Dental implant surgery,
Head and neck pathology, Complex maxillofacial reconstructive surgery, Outpatient anesthesia,
Aesthetic surgery, Sleep apnea surgery, Advanced presprosthetic surgery, Dentoalveolar surgery,
Cleft lip/palate and craniofacial surgery, Oral cancer surgery.
V. Achievement goal
The post-graduate students will have got the way of learning about how to structured scientific evidence
upon completion of this program. And also it will be able to play a role as a medical scientist on the basisof scientific skill. In addition, the candidate could be advance in the field of research and lead the mostadvanced dental science. The possibility of becoming the next leaders and human resources that
contribute to the improvement of dentistry as an oral and maxillofacial surgeon is proposed.
VI. Strategy (Conferred a degree equivalent to a bachelor's degree)
1. Training course of oral and maxillofacial surgery: Year1
2. Basic research for producing quality theses: Year 2, 3, and 4
3. Undergraduate student lecture: 1 credit per year or more
4. Oral Oncology, Oral and Maxillofacial surgery lecture: 10 credit per year or more
5. Meeting: 1 credit per month
6. Journal club: 1 credit per month
7. Case conference: every day
8. Present research results at a conference: as needed
9. Join external workshops: as needed
VII. Formative evaluation (Conferred a degree equivalent to a bachelor's degree)
Achieve a passing score: Oral examination, Report, Portfolio
VIII Prospects after completion of graduate school
1. Senior resident or associate professor (Department of Oral Oncology, Oral and Maxillofacial
surgery)
2. Clinical staff in affiliated hospital
3. Staff in formal or international laboratory (post-doctoral fellow)-2-

IX. Oral Oncology, Oral and Maxillofacial surgery lecture
1. Oral and Maxillofacial Surgery (1.5h)
2. Oral Medicine (1.5h)
3. Oral Oncology (1.5h)
4. Dental anesthesiology (1.5h)
5. Surgical Pathology (1.5h)
6. Surgical anatomy (1.5h)
7. Emergency medicine (1.5h)
8. Team medicine (Nutrition Support Team) (1.5h)
9. Supportive care (oral management, dysphagia rehabilitation, oral and maxillofacial prosthesis andimplant) (1.5h)
10. Palliative medicine (1.5h)-3-Department of Oral Medicine and Hospital Dentistry
Ⅰ．Instructional objectives
Oral Medicine and Hospital Dentistry is an academic discipline primarily concerned with attending
to healthcare in cooperation with medicine, dentistry, and many other disciplines based not only on asurgical approach, but on a multifaceted view and knowledge of the diagnosis and treatment of oraldiseases that considers their systemic and genetic background. In this course, students aim to obtain adoctorate (in dentistry) by acquiring the international-level information-gathering and analysis
capabilities necessary for basic and clinical research, and preparing a dissertation that compiles
research on oral medicine and hospital dentistry that can contribute to the progress of dental medicine.

Ⅱ．Primary areas of research・The effects of psychiatric sedatives on biological functions
・The pathology of dysphagia and oral management in patients with acute stroke
・The relationship between caries-causing bacteria and the risk of stroke・Perioperative management of oral function: effects and standard techniques
・Dental approaches to feeding and dysphagia
・Sarcopenia and oral dysfunction
・Diagnosis and treatment of dysphagia in patients following tongue cancer surgery
・Diagnosis and treatment of dysfunction in patients with maxillofacial defects
・Sleep apnea

Ⅲ．Features of the course
The course is set up at Tokyo Dental College Ichikawa General Hospital. The hospital’s
flagship department is the Department of Dentistry and Oral Surgery, which covers oral medicine,
dentistry for medically compromised patients and disabled patients, perioperative management of oral
function, dysphagia rehabilitation, maxillofacial prosthetics, and oral surgery. The department is staffedwith certified physicians and clinical instructors specializing in all fields, allowing students to obtaincertifications from various academic societies while enrolled in graduate school. Thus, a defining
feature of this course is that it provides many opportunities for students to engage proactively not only
in research but also in clinical practice. The research involved is distinctively collaborative, as it
includes not only basic research on medical and clinical dentistry, but also a wide variety of diseases
for which students can engage in diagnosis and treatment in coordination with adjacent medical
departments.

Ⅳ．A unique course curriculum
・A program in which students participate in medical training in adjacent medical departments (with thepossibility of choosing from Internal Medicine, Surgery, Anesthesia, and other departments) at
Ichikawa General Hospital to acquire knowledge and clinical skills related to medical diseases andsystemic management
・Mastering diagnosis/treatment regimen planning and patient management through clinical experience
beginning in year 1
・Meeting with instructors once a month and making intra-office research progress reports
・Participating in journal clubs, group discussions, and clinical conferences
・Presenting a report on a case or simple research results at an academic conference and publishing apaper in a professional journal in year 2・Medical office-led exam prep courses for obtaining certification from various academic societies

Ⅴ．Achievement objectives
・Acquire knowledge of basic medical diseases and learn systemic management of diseases in medical
training.
・Acquire the information-gathering and analysis capabilities necessary for basic and clinical research.
・Present dissertation research results at an academic conference (domestic or international) andcomplete a dissertation.
・Acquire the research capability, capacity for providing educational guidance, and basic clinical skills
to be a leader in next-generation dentistry settings.
・Obtain certification from academic societies while enrolled in, or shortly after completing, graduate
school.

Ⅵ．Learning strategy
・Medical office-led lectures（5 times/year）
・Graduate school seminars（8 times/year）
・Research for dissertation preparation（2nd grade - 4th grade）
・medical training（6 months during the 1st grade）
・Journal clubs（monthly）
・Progress report meetings（monthly）
・clinical conferences（as needed）

・Participation in/presentation at academic conferences（as needed）
・Participation in workshops（as needed）

Ⅶ．Assessment methods/criteria
・In regard to the validity of experiment data, summary of experimental results, and manuscript
preparation, progress is confirmed at monthly graduate school meetings, where general assessment isconducted via oral examination, reports, and portfolios.
・For oral examinations, reports, and portfolios, a passing score is 6 points or higher for each.

Ⅷ．Prospects after graduate school・Oral Medicine and Hospital Dentistry course resident or assistant professor
・Working in a clinical setting as a dentist capable of systemic management in the department ofdentistry and oral surgery at an affiliated hospital・Working in a clinical setting as a dentist capable of systemic management in regional dental
associations and dental centers
・Studying at an affiliated research institution outside Japan

Ⅸ．Lecture contents
・Oral Medicine（1.5h×3）・Adjacent Medicine（1.5h×6）（Internal Medicine, Surgery, Anesthesia etc.）
・Dental anesthesiology（1.5h×3）
・Oral and Maxillofacial Surgery（1.5h×3）
・Dentistry for medically compromised patients and disabled patients（1.5h×3）
・Dysphagia rehabilitation（1.5h×2）
・Oral and maxillofacial prosthesis（1.5h×2）
・Oral pathology（1.5h×2）
・Emergency medicine, Basic life support（1.5h×2）・Team medicine（1.5h×2）（Multidisciplinary cooperation：NST, RST, Home visiting nursing）
・Perioperative management of oral function（1.5h）
・Oral implantology（1.5h×2）