The 34th Annual Scientific Meeting of the British Society ofToxicological Pathology (BSTP)
held jointly with the British Toxicology Society (BTS)
EMERGENT EPIGENETIC THERAPIES
Tuesday 19th & Wednesday 20th November 2019
Hilton Newcastle and Gateshead Hotel, Bottle Bank, Gateshead, UK

REGISTRATION IS STILL OPEN
AND WILL CLOSE AT MIDNIGHT ON SUNDAY 20th OCTOBER 2019
Approximately 11.5 hours of educational activity will be recorded on Attendance Certificates
Approved by the Royal Society of Biology for purposes of CPD, this event may be counted as 36 credits

If you have any queries regarding this meeting, please contact the BSTP Secretariat bstpoffice@aol.com or visit the BSTP website:
http://www.bstp.org.uk/bstp-bts-joint-meeting/1

Welcome
The BSTP’s 34th Annual Scientific Meeting will, this year, be held jointly with the British Toxicology
Society (BTS) and will cover the topic of emergent epigenetic therapies.
Recently we have seen an explosion of discoveries related to the cellular regulation of phenotypes
through epigenetic mechanisms. As epigenetic changes are reversible, this offers the potential for
epigenetic therapies based on cellular reprogramming (e.g. cancer, neuro degenerative disease), withfurther opportunities in the detection of microRNAs (e.g. blood, exhaled air) and their use as
diagnostic tools.
The Organising Committee are working to bring experienced researchers from all over the world, as
well as leaders in the industry to discuss recent advances in epigenetic therapies. This meeting will
include talks from academic researchers investigating the role of epigenetics in various diseases.
There will also be presentations from toxicologists/pathologists working in pharmaceutical/
biotechnology companies exploring epigenetic mechanisms and their therapeutic/diagnostic
potential.
The first day of the meeting will include the Annual General Meeting of the BSTP, followed by a drinks
and canapé reception.
Submission of abstracts for THE BSTP/BTS MEETING on Emergent Epigenetic Therapies• Abstracts should be submitted using the online system.
• Abstracts should be no more than 500 words in total, to include references.
• Abstracts will be printed in black and white.
Bursaries
Five free places will be available for PhD students/residents working in the field of toxicology or
toxicologic pathology. Applications to be submitted to the BSTP Secretariat by 30th August 2019 forapproval by a representative of the BSTP and BTS. The five approved applicants will be required toprovide an article on the meeting (or their own research) to both societies for publication in theirrespective newsletters OR present a poster at the meeting.
Sponsorship and Promotional Opportunities
We feel that by participating in this conference it would allow your company to showcase a range ofproducts to a diverse group of toxicological and experimental pathologists. Please contact the BSTP
at bstpoffice@aol.com more information.
IMPORTANT DEADLINES
 Applications for the bursaries will close at midnight on Monday 30th September 2019 The deadline for the submission of abstracts is 4pm on Monday 30th September 2019 Early bird registration has been extended and will end at midnight on Sunday 13th October
2019 Registration will close at midnight on Sunday 20th October 2019
So, if you are you looking for some high quality CPD and would you like to broaden yourunderstanding on epigenetics this is the meeting for you.
We hope to see you in November!

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Programme
08.30 - 09.30Tuesday 19th November 2019
Registration

08.30 - 09.00

Committee Meeting of the BSTP and BTS Scientific Committee

09.30 - 09.45

Welcome Introduction
Dr Begonya Garcia, President of the BSTP

09.45 - 10.30

Getting up close and personal with epigenetics in health and disease (overview)
Professor Ann Daly, Newcastle University, UK

10.30 - 11.00
11.00 - 11.45
11.45 - 12.30
12.30 - 13.00
13.00 - 13.45
13.45 - 14.30

14.30 - 15.15
15.15 - 15.30
15.30 - 16.00
16.00 - 17.00

Refreshments and Poster Exhibition
The epigenome as a mediator of environmental effects on development and implications
in disease development
Professor Richard Meehan, University of Edinburgh, UK
Environmentally induced epigenetic toxicity
Dr Emma Marczylo, Public Health England, UK
Technology on the Pitch
Complimentary “elevator pitch” from the Trade Exhibitors
Lunch and Poster Exhibition
Epigenetic transgenerational effects promoted by toxicants
Dr Fatima Smagulova, Research Institute for Environmental and Occupational Health,FranceGenomic imprinting, developmental programming and adverse effects of early life
environments
Dr Robert Feil, IGMM, France
Short Oral Communication
To be confirmed
Refreshments and Poster ExhibitionEpigenetic effects of endocrine disrupting chemicals: Mechanisms, evaluation andpathologies
Dr Joëlle Rüegg, Karolinska Institute, Sweden

17.00 - 18.00

BSTP Annual General Meeting18.00 onwards

Drinks and Canapé Reception

You are advised that the programme timings, lecture title and speakers may be subject to change without notice3

Provisional Programme
08.30 - 09.00
09.00 - 09.15
09.15 - 10.00
10.00 - 10.45

Wednesday 20th November 2019
Registration and Poster Exhibition
Introduction to Day 2
Dr Chris Powell, President of the BTS - tbc
Epigenetic modifications and cancer
Dr Maria Berdasco, Josep Carreras Leukaemia Research Institute (IJC), Spain
Epigenetic acetylation and disease pathologies: More than just histones!
Professor Patrick Matthias, FMI, Switzerland

10.45 - 11.15

Refreshments and Poster Exhibition

11.15 - 12.00

Epigenetic mechanisms in cognitive impairment linked to aging and Alzheimer's disease
Dr Christian Griñán-Ferré, University of Barcelona, Spain

12.00 - 13.00

Epigenetics and liver fibrosis
Professor Jelena Mann, Newcastle University, UK

13.00 - 13.45
13.45 - 14.45
14.45 - 15.30
15.30 - 16.00
16.00 - 16.30

16.30 - 17.0017.00

Lunch and Poster ExhibitionNon-clinical safety considerations for the development of emerging epigenetic therapies
Dr Remi Terranova, Novartis, Switzerland
Pre-clinical development of epigenetic therapies: Drugging bromodomains
Dr Inma Rioja Pastor, GlaxoSmithKline, UK
Refreshments and Poster Exhibition
Pathology case study
Dr Thierry Flandre, Novartis, Switzerland
Roundtable discussion
Emergent epigenetic therapies and toxicity: Pathological landscape?
Chairs: To be confirmed
Closing Remarks

You are advised that the programme timings, lecture title and speakers may be subject to change without notice4Registration
THE EARLY REGISTRATION FEE HAS BEEN EXTENDED AND WILL NOW END AT MIDNIGHT ON
SUNDAY 13TH OCTOBER 2019!

Registration

Full meeting registration fee
Before 13th Oct After 13th Oct
2019
2019
£350.00£440.00£450.00£560.00

Day delegate registration fee
Before 13th Oct After 13th Oct
2019
2019
£210.00£265.00£320.00£400.00

BSTP/BTS Member
Non-Member
Early Career Pathologist/£200.00£250.00£140.00£175.00
Toxicologist * see below
BSTP/BTS Student Member£100.00£125.00£70.00£87.50* Early Career Pathologist/Toxicologist you are required to provide written confirmation of your status fromyour Head of Department (on headed paper) when submitting your registration form.

Full meeting registration fee includes: All scientific sessions including a USB flash drive
containing the meeting booklet; attendance certificate and refreshments during breaks andlight lunches on both days. Attendance at the evening drinks and canapé reception on thefirst day of the meeting.
Day delegate registration fee includes: All scientific sessions on the day booked including aUSB flash drive containing the meeting booklet; attendance certificate and refreshments
during breaks and a light lunch. Attendance at the evening drinks and canapé reception is
only applicable upon booking attendance at the first day of the meeting.
A list of the terms and conditions is available on the online registration form.
Cancellation Policy: All requests for cancellations to bookings must be received in writing by
30th September 2019. Refund requests received up to 30th September 2019 will incur a 25%
processing fee. Refund requests received after 30th September 2019 will not be processed.
Those who cancel after 20th October 2019 and have not paid will be invoiced for the fullamount.
Replacements: Substitutions can be made at any time up to 20th October 2019.
If you have any queries, please contact:
BSTP Secretariat
BSTP │ PO Box 819 │ Harrogate │ North Yorkshire HG1 9XF │ UK
Tel:
Email:
Website:+ 44 (0)7894 123 533
bstpoffice@aol.com
www.bstp.org.uk

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Bursary Opportunities
The BSTP and BTS are delighted to announce that there are still free places available for stipendiarystudents studying a relevant pathology or toxicology project, or pathology and/or toxicology
residents/trainees/early career pathologists/toxicologists. Applications to be submitted by 30th
September to the BSTP President – Begonya Garcia - begonya.garcia@crl.com for approval by arepresentative of the BSTP and BTS. The five approved applicants will be required to provide a shortarticle on the meeting (or their own research) to both societies for publication in their respective
newsletters or present a poster at the meeting.
In addition (if not already a member of the BSTP), successful candidates will be invited to join thesociety and will receive a year’s free membership of the BSTP worth £60.
Applications will be assessed by representatives from the BSTP and BTS on merit.
Successful applicants will be notified on or before 14th October 2019.
To apply, please include:
A brief description of the relevance of the meeting to your training or career requirements andprovide the following information:a.

A brief CV.

b.

A letter of recommendation from your supervisor or Head of Department.

c.

Up to 3 suggestions for future educational activities/topics that would be helpful to yourtraining in toxicological pathology or toxicology.

d.

If not already a member of the BSTP, request and complete an application form formembership of the BSTP to enable you to access a year’s free membership (worth £60).

e.

An abstract of your posterf.

After the meeting has taken place, an article on the meeting (or your own research) should
be sent to both societies for publication in their newsletters.

Submission of Abstracts for BSTP-BTS congress on Emergent Epigenetic Therapies•Abstracts should be submitted using the Online system•
Abstracts should be no more than 500 words in total, to include references.
•Abstracts will be printed in black and white.
For more details please visit:
http://www.bstp.org.uk/events/34th-annual-scientific-meeting-agm-held-jointly-with-the-bts/

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How to get there…………….

Hilton Newcastle and Gateshead Hotel
Bottle BankGateshead NE8 2AR
UK
Tel: +44 191 490 9739
Web: https://www3.hilton.com/en/hotels/united-kingdom/hilton-newcastle-gatesheadNCLHIHI/index.html
VIEW MAPBY ROADThe Hilton hotel in Gateshead is located on the scenic south shore of the Quayside, about 10minutes' walk from the city centre.
••••

At roundabout, take 3rd exit onto A184 / Askew Road toward Gateshead Quays / Gateshead
Town Centre / A184 (0.8 mi.)Turn left onto A167 (0.0 mi.)Bear left onto Bottle Bank (0.1 mi.)Arrive at Bottle Bank (0.0 mi.)For detailed road information via the A1(M), check your route using http://www.bing.com/maps/

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BY PUBLIC TRANSPORT

If you are travelling by train,
https://www.nationalrail.co.uk/

checkwiththeNationalRailEnquiryLine-From the railway station it is approximately a 13-minute walk to Bottle Bank via the A186 High Level
Bridge, or if you prefer to travel by taxi it is a 10-minute journey.

BY AIR

Driving time from Newcastle International Airport is approximately 20 minutes.
Check the hotel link for more information:
https://www3.hilton.com/en/hotels/united-kingdom/hilton-newcastle-gateshead-NCLHIHI/mapsdirections/index.html

LOCAL TAXISYou need to be aware that at peak times there may be a delay in a taxi reaching you. You are strongly
advised to book your taxi well in advance of the time it is required. If you require a taxi from the hotelto the airport or railway station you are advised to book it in the evening through the Conierge at yourhotel.

Need somewhere to stay?
All delegates are responsible for making their own travel and accommodation arrangements.
The BSTP and BTS have been able to secure a limited number of rooms at a preferential room rate at
the Hilton Newcastle and Gateshead Hotel:
http://eventsathilton.com/show/5c9ca6fc581e402ab482fe8a£119.00 – single room per night including breakfast£129.00 – double room per night including breakfast
If you book accommodation at the hotel, please inform the BSTP Secretariat so that, if necessary, wecan increase the number of rooms available.
Other hotels in the area:
If you need to find other hotels in the area put Newcastle upon Tyne into a hotel search engine suchas http://www.hotels.com or http://www.booking.com or https://www.trivago.co.uk
Please don’t hesitate to contact bstpoffice@aol.com if you have problems finding a suitable hotel.

Disclaimer
The BSTP and BTS have made every effort to ensure that the information above is accurate,
however all items are subject to change from time to time. The BSTP and BTS have no control
over links that are presented in this file and you visit them at your own risk. The inclusion of
any link in this file does not mean that the BSTP and BTS endorse the activities, products or
views of that particular organisation. The BSTP and BTS does not intend to create any
contractual agreement or other legal relation with members or any other person.

8Sponsors
There are a number sponsorship opportunities still available, if your company is interested inproviding sponsorship for this event, either financial or by the provision of delegate materials,
please contact the BSTP Secretariat as soon as possible – bstpoffice@aol.com

THIS COULD BE YOUR
COMPANY LOGO!

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