Safety Summary Sheet
Silicic acid, aluminum sodium salt（CAS NO. 1344-00-9）
SPECIES

Silicic acid, aluminum sodium salt

PROTOCOL

RESULTS（CAS NO.: 1344-00-9）
PHYSICAL-CHEMICAL
2.1

Melting Point

2.2

Boiling Point

2.3

DensityUnknown(analogicallybased)ca. 1700 ℃*1

Not relevant

2.4

Vapour Pressure

2.5

Partition Coefficient(log Kow)

2.6.1A

Water Solubility

2.6.1.B

Dissociation Constant（pKa）

DIN/ISO 787/11

Density : ca. 2.1 g/cm3 (20 ℃)

DIN/ISO 787/11

Bulk density : 220 – 300 kg/m3

Unknown

Not vaporized (20 ℃)
Not relevant(due to inorganic compound)

Directive92/69/EEC, A.6

ca. 70 – 80 mg/l (20 ℃)
No data

ENVIRONMENTAL FATE AND PATHWAY
3.1.1

Photodegradation

Unknown

Stable (no degradation)

3.1.2

Stability in Water

Unknown

Stable (no degradation, ion exchangepossible)

3.1.3

Stability in Soil

Unknown

Stable (ion exchange possible)

3.2

Monitoring Data

3.3.1

Transport between
Environmental Compartments

3.3.2

Distribution

3.4

Biodegradation

Not relevant(due to inorganic compound)

3.5

BOD-5, COD or BOD-5／
COD ratio

See 3.4

3.6

Bioaccumulation

Bioaccumulation of silicates can bedisregarded. But silica can be activelyaccumulated by terrestrial plants andsome marine organisms

No data
Expected to be distributed mainly into
solids/sediments
No data(Koc etc.）

ECOTOXICOLOGY
4.1

Acute Toxicity to Fish

Brachydanio
rerioOECD TG 203

LC0(96 h) : 10000 mg/l (static, limittest)*2

4.2

Acute Toxicity to Aquatic
Invertebrates (Daphnia etc.)

Daphnia magna

Unknown(analogicallybased)

EC50(24 h) : >10000 mg/l*1*2

4.3

Toxicity to Aquatic Plants(Algae etc.)

Scenedesmus
subspicatus

OECD TG 201

NOEC(72 h) : 10000 mg/l*2

4.4

Toxicity to Microorganisms(Activated Sludge Respiration
Inhibition test etc.)

No data

4.5.1

Chronic Toxicity to Fish

No data

4.5.2

Chronic Toxicity to Aquatic
Invertebrates

No data1

Silicic acid, aluminum sodium salt

SPECIESPROTOCOL

RESULTS（CAS NO.: 1344-00-9）
4.6

Toxicity to Terrestrial
Organisms

No data

4.6.1

Toxicity to Sediment Dwelling
Organisms

No data

TOXICOLOGY
5.1

Toxicokinetics, Metabolism
and Distribution

5.2

Acute Toxicity

A.

Acute Oral Toxicity

B.

Acute Inhalation Toxicity

C.

Acute Dermal Toxicity

D.

Acute Toxicity, Other Routes

5.3

RatUnknown(oral gavage,absorption andexcretion)

After being decomposed in thegastro-intestinal tract, silicon wasslightly absorbed and excreted intourine

Rat

Unknown

LD50 : > 5000 mg/kg
No data

RabbitUnknown

LD50 : > 5000 mg/kg
No data

Irritation/Corrosion

A.

Skin Irritation/Corrosion

RabbitPatch test
Fed. Hazardous
Substances Act,
Section 101.11

Not irritatingB.

Eye Irritation/Corrosion

RabbitFed. Hazardous
Substances Act1973

Not irritating

5.4

Skin Sensitization

No data

5.5

Repeated Dose Toxicity

No data*3

5.6

Genetic Toxicity in vitro

A.

Gene Mutation(Bacterial Test etc.)

B.

Chromosomal Aberration

5.7

Genetic Toxicity in vivo

5.8

Carcinogenicity

5.9

Toxicity to Reproduction

A.

Toxicity to Fertility

B.

Developmental

S. typhimurium

Unknown（NTP study）

Negative
No dataRat

Unknown(oral gavage,Chromosomal
aberration)

Negative

Rat

Unknown(oral gavage,Dominant lethalassay)

Negative

Rat

Unknown (single
intra-pleuralinjection,
maximally 3 yearsobservation)

Not carcinogenic

No data*4Rat

Unknown(oral gavage,2NOAEL :Maternal & developmental ;Silicic acid, aluminum sodium salt

SPECIESPROTOCOL

RESULTS（CAS NO.: 1344-00-9）
Toxicity/Teratogenicity

Rabbitexposed during
6-15 gestationdays(organogenesisperiod))

1600 mg/kg/day
Not teratogenic

Unknown(oral gavage,exposed during
6-18 gestationdays(organogenesisperiod))

NOAEL :
Maternal & developmental ;1600 mg/kg/day
Not teratogenic

5.10

Other relevant information

No data

5.11

Experience with HumanExposure

No data*1 : Based on analogy with similar substances (e.g. silica)*2 : Greater than the solubility in water.
*3 : An effects profile similar to that of synthetic amorphous silica (SAS) is supposed, based on the assumption thatthe particle size and morphology rather than particle composition is the determinant of inflammatory response in
the lung (OECD SIAR). For SAS, NOAEC of 1 mg/m3 is derived in rats 13 weeks sub-chronic inhalation study.
*4 : Based on structure analogy with SAS, no impairment of fertility/reproductive performance is expected to occur(OECD SIAR).

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implicitly understood that Sumitomo Chemical makes no warranty or assumes no liability or
obligation for the data and information provided.

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