過去 3 年の研究業績
Fukui S, Inui A, Saita M, Kobayashi D, Naito T. Clinical prediction rule for bacteremia withpyelonephritis and hospitalization judgment: chi-square automatic interaction detector(CHAID) decision tree analysis model. J Int Med Res. 2022 Jan;50(1):3000605211065658. doi:
10.1177/03000605211065658. PMID: 34986702; PMCID: PMC8743944.
Kayama M, Aoki Y, Matsuo T, Kobayashi D, Taki F. Concerns and desires of healthcare workers
caring for patients with COVID-19 in April and July 2020 in Japan: a qualitative study of openended survey comments. BMJ Open. 2022 Jan 7;12(1):e051335. doi: 10.1136/bmjopen-2021051335. PMID: 34996787; PMCID: PMC8743838.
Fukui S, Shimbo T, Kobayashi D. Both increased and decreased sleep duration over time areassociated with subsequent cancer development. Sleep Breath. 2021 Dec 3. doi:
10.1007/s11325-021-02517-7. Epub ahead of print. PMID: 34860321.
Kobayashi D, Yamamoto K, Kimura T, Shimbo T. Aspartate aminotransferase/alanine
aminotransferase ratio and subsequent cancer development. Cancer Med. 2021 Dec 1. doi:
10.1002/cam4.4473. Epub ahead of print. PMID: 34850600.
Fukui S, Inui A, Saita M, Kobayashi D, Naito T. Clinical prediction rule for bacteremia withpyelonephritis and hospitalization judgment: chi-square automatic interaction detector(CHAID) decision tree analysis model. J Int Med Res. 2022 Jan;50(1):3000605211065658. doi:
10.1177/03000605211065658. PMID: 34986702; PMCID: PMC8743944.
Yamamoto K, Ikeya T, Fukuda K, Kobayashi D. Comparison in the Development of colorectal
cancer after screening colonoscopy between elderly and younger population. EJCP (article inpress)
Osugi Y, Ishiguro K, Kobayashi D. Association Between Antidiarrheal Drug Prescription andReturn Visits Among Adult Patients With Acute Diarrhea. Cureus. 2021 Oct 15;13(10):e18807.
doi: 10.7759/cureus.18807. PMID: 34796079; PMCID: PMC8590859.
Kobayashi D, Yokota K, Yamagata-Uyama S, Saito M. Factors associated with the detectionof norovirus among asymptomatic adults. Clin Microbiol Infect. 2021 Jun 11:S1198743X(21)00321-9. doi: 10.1016/j.cmi.2021.06.004. Epub ahead of print. PMID: 34126230.

Numata K, Matsubara T, Okumura Y, Kondo K, Shirakami M, Kobayashi D. Development ofClinical Skills and Confidence Questionnaire for Triage and Action Minor Emergency Course:
Test-Retest Exam. Cureus. 2021 Sep 10;13(9):e17864. doi: 10.7759/cureus.17864. PMID:34660066; PMCID: PMC8502750.
Matsuo T, Taki F, Kobayashi D, Jinta T, Suzuki C, Ayabe A, Sakamoto F, Kitaoka K, Uehara Y,Mori N, Fukui T. Health care worker burnout after the first wave of the coronavirus disease2019 (COVID-19) pandemic in Japan. J Occup Health. 2021 Jan;63(1):e12247. doi:
10.1002/1348-9585.12247. PMID: 34375497; PMCID: PMC8354617.
Tomita S, Kuga T, Osugi Y, Kobayashi D. Factors associated with the accomplishment of home
death among patients receiving physician-led home healthcare. Geriatr Gerontol Int. 2021
Jun;21(6):525-531. doi: 10.1111/ggi.14173. Epub 2021 Apr 27. PMID: 33904229.
Kobayashi N, Noguchi T, Kobayashi D, et al. Safety and Efficacy of Percutaneous
Vertebroplasty

forOsteoporoticVertebral

Compression

Fractures:A

Multicenter

Retrospective Study in Japan. Interventional Radiology. 2021;6(2):21-28.
Yamamoto K, Ikeya T, Okuyama S, Fukuda K, Kobayashi D. Association between theFrequency of Daily Toothbrushing and Development of Nonalcoholic Fatty Liver Disease. Dig
Dis. 2021;39(6):646-652. doi: 10.1159/000514930. Epub 2021 Feb 3. PMID: 33535206.
Wake M, Kobayashi D. Associations between plasma levels of omega-3 fatty acids andsubsequent

allergic

diseases.

ClinNutr

ESPEN.

2021

Apr;42:318-324.

doi:

10.1016/j.clnesp.2021.01.013. Epub 2021 Feb 3. PMID: 33745599.
Hirano K, Shimbo T, Komatsu Y, Kobayashi D. Frequency of tooth brushing as a predictive
factor for future kidney function decline. J Nephrol. 2021 Feb 22. doi: 10.1007/s40620-02100987-2. Epub ahead of print. PMID: 33616857.
Numata K, Matsubara T, Kobayashi D. Improvement of physician's confidence in handlingminor emergencies before/after triage and action minor emergency course. Acute Med Surg.
2021 Jan 19;8(1):e624. doi: 10.1002/ams2.624. PMID: 33510898; PMCID: PMC7814961.
Yamamoto K, Ikeya T, Okuyama S, Okamoto T, Fukuda K, Kobayashi D. Negative correlation

of high serum bilirubin with cancer development in adults without hepatobiliary disease. EurJ Cancer Prev. 2021 Jan;30(1):69-75. doi: 10.1097/CEJ.0000000000000643. PMID: 33086248.
Matsuo T, Takahashi O, Kitaoka K, Arioka H, Kobayashi D. Resident Burnout and Work
Environment. Intern Med. 2021 May 1;60(9):1369-1376. doi: 10.2169/internalmedicine.587220. Epub 2020 Dec 7. PMID: 33281158; PMCID: PMC8170257.
Yamamoto K, Ikeya T, Okuyama S, Fukuda K, Kobayashi D. The association between nonalcoholic fatty liver disease (with or without metabolic syndrome) and extrahepatic cancer
development. J Gastroenterol Hepatol. 2021 Jul;36(7):1971-1978. doi: 10.1111/jgh.15350.
Epub 2020 Dec 13. PMID: 33201570.
Kuriyama N, Ozaki E, Koyama T, Matsui D, Watanabe I, Tomida S, Nagamitsu R, Hashiguchi K,Inaba M, Yamada S, Horii M, Mizuno S, Yoneda Y, Kurokawa M, Kobayashi D, Fukuda S, Iwasa
K, Watanabe Y, Uehara R. Evaluation of myostatin as a possible regulator and marker ofskeletal muscle-cortical bone interaction in adults. J Bone Miner Metab. 2021 May;39(3):404415. doi: 10.1007/s00774-020-01160-8. Epub 2020 Oct 12. PMID: 33044569.
Kobayashi D, Shimbo T. Longitudinal sleep duration and subsequent development of cancer
intheJapanese

population.

Neoplasma.

2020

Sep;67(5):1182-1190.

doi:

10.4149/neo_2020_200219N154. Epub 2020 Jul 24. PMID: 32701356.
Kobayashi D, Mizuno A, Mitsui R, Shimbo T. Frequency of daily tooth brushing andsubsequent cardiovascular events. Coron Artery Dis. 2020 Sep;31(6):545-549. doi:
10.1097/MCA.0000000000000882. PMID: 32310852.
Kobayashi D, Mizuno A, Shimbo T, Aida A, Noto H. The association of repeatedly measured
low-density lipoprotein cholesterol and all-cause mortality and cardiovascular disease in
dyslipidemic patients: A longitudinal study. Int J Cardiol. 2020 Jul 15;311:97-103. doi:
10.1016/j.ijcard.2020.03.011. Epub 2020 Mar 6. PMID: 32173131.
Kobayashi D, Kuriyama N, Noto H, Aida A, Takahashi O, Shimbo T. Development ofmalignancies and changes in time-dependent hemoglobin A1c among a nondiabetic
population:

longitudinalanalysis.

ActaDiabetol.

2020

10.1007/s00592-019-01396-5. Epub 2019 Aug 9. PMID: 31399781.

Feb;57(2):189-196.

doi:

Kobayashi D, Noto H, Takahashi O, Shimbo T. Glycemic variability and subsequentmalignancies among the population without diabetes. Diabetes Res Clin Pract. 2020
Jan;159:107987. doi: 10.1016/j.diabres.2019.107987. Epub 2019 Dec 19. PMID: 31866528.
Kobayashi D, First MB, Shimbo T, Kanba S, Hirano Y. Association of self-reported religiositywith the development of major depression in multireligious country Japan. Psychiatry Clin
Neurosci. 2020 Oct;74(10):535-541. doi: 10.1111/pcn.13087. Epub 2020 Jul 5. PMID:
32618044; PMCID: PMC7586836.
Tasaki A, Nozaki T, Morita W, Kobayashi D, Phillips BB, Kitamura N. The relationship between
high-signal intensity changes in the glenohumeral joint capsule on MRI and clinical shoulder
symptoms. Asia Pac J Sports Med Arthrosc Rehabil Technol. 2020 Jul 31;22:27-33. doi:10.1016/j.asmart.2020.06.001. PMID: 32802748; PMCID: PMC7398897.
Miyazawa R, Matsusako M, Nozaki T, Kobayashi D, Kojima F, Bando T, Tateishi U. Incidental
mediastinal masses detected at low-dose CT screening: prevalence and radiologicalcharacteristics. Jpn J Radiol. 2020 Dec;38(12):1150-1157. doi: 10.1007/s11604-020-01015-2.
Epub 2020 Jul 7. PMID: 32638279.
Matsuo T, Deshpande GA, Arioka H, Kobayashi D. Association of Residency Training With
MetabolicMeasures.

JAMANetwOpen.

2020Apr1;3(4):e205120.

doi:10.1001/jamanetworkopen.2020.5120. PMID: 32352528; PMCID: PMC7193327.
Yamamoto K, Takahashi O, Kobayashi D. Comparison of risk factors between humanintestinal

andgastricAnisakiasis.

ParasitolInt.

2020

Apr;75:102024.

doi:10.1016/j.parint.2019.102024. Epub 2019 Nov 12. PMID: 31730806.
Kanemura H, Tamura T, Nishimura N, Kobayashi D, Higashi T. Thymic epithelial tumor
treatment in Japan: analysis of hospital cancer registry and insurance claims data, 2012-2014.
Jpn J Clin Oncol. 2020 Mar 9;50(3):310-317. doi: 10.1093/jjco/hyz167. PMID: 31829410;
PMCID: PMC7061247.
M Matsuda K, Arioka H, Kobayashi D. Risk factors of partial IgA deficiency among low serum
IgA patients: a retrospective observational study. Cent Eur J Immunol. 2020;45(2):189-194.
doi: 10.5114/ceji.2020.97908. Epub 2020 Jul 27. PMID: 33456330; PMCID: PMC7792431.

Kobayashi D, Goto R, Tsugawa Y. Impact of improved price transparency on patients' demandofhealthcareservices.

Soc

SciMed.

2019

Aug;235:112390.

doi:10.1016/j.socscimed.2019.112390. Epub 2019 Jul 9. PMID: 31325901.
Kobayashi D, Takahashi O, Shimbo T. Frequency of Daily Tooth Brushing and Developmentof

anyTypeofMalignancy.

AnticancerRes.

2019Aug;39(8):4415-4421.

doi:

10.21873/anticanres.13613. PMID: 31366539.
Kobayashi D, Noto H, Shimbo T, Ino T, Osugi Y, Takahashi O, Asai K. Repeated measures ofextremely high levels of high-density lipoprotein cholesterol and subsequent all-cause
mortality and cardiovascular events: A longitudinal study. Atherosclerosis. 2019 Sep;288:1725. doi: 10.1016/j.atherosclerosis.2019.06.918. Epub 2019 Jun 29. PMID: 31295627.
Kobayashi D, Shimbo T, Hayashi H, Takahashi O. Shiatsu for chronic lower back pain:
Randomizedcontrolledstudy.

ComplementTherMed.

2019

Aug;45:33-37.

doi:

10.1016/j.ctim.2019.05.019. Epub 2019 May 16. PMID: 31331579.
Kobayashi D, Shimbo T, Noto H, Eto H, Takahashi O, Higuchi T. Low level of hemoglobin A1c
and the increased incidence of herpes zoster: longitudinal study. Eur J Clin Microbiol InfectDis. 2019 Aug;38(8):1539-1545. doi: 10.1007/s10096-019-03584-1. Epub 2019 May 20. PMID:31111373.
Kobayashi D, Kuriyama N, Yanase F, Takahashi O, Aoki K, Komatsu Y. Angiotensin-converting
enzyme inhibitor/angiotensin II receptor blocker use prior to medical intensive care unit
admission and in-hospital mortality: propensity score-matched cohort study. J Nephrol. 2019
Aug;32(4):595-603. doi: 10.1007/s40620-019-00603-4. Epub 2019 Apr 1. PMID: 30937855.
Kobayashi D, Hayashi H, Kuga H, Kuriyama N, Terasawa Y, Osugi Y, Takahashi O, Deshpande
G, Kawachi I. Alcohol consumption behaviours in the immediate aftermath of earthquakes:
time series study. BMJ Open. 2019 Mar 7;9(3):e026268. doi: 10.1136/bmjopen-2018-026268.
PMID: 30850415; PMCID: PMC6429926.
Kobayashi D, Saito M, Heike Y, Yokota K, Arioka H, Oshitani H. The association between
consuming bivalves, and acute gastroenteritis and norovirus in Tokyo, Japan. J Med Virol.
2019 Jun;91(6):986-996. doi: 10.1002/jmv.25416. Epub 2019 Feb 7. PMID: 30698827.

Osugi Y, Ino T, Kobayashi D, Iwata M, Asai K. Effect of continuation of antiplatelet therapy
on survival in patients receiving physician home visits. BMC Geriatr. 2019 Dec 23;19(1):366.
doi: 10.1186/s12877-019-1394-6. PMID: 31870311; PMCID: PMC6929486.
Oguri N, Ikeya T, Kobayashi D, Yamamoto K, Yoshimoto T, Takasu A, Okamoto T, Shiratori Y,Okuyama S, Takagi K, Nakamura K, Fukuda K. Effectiveness of risk scoring systems inpredicting endoscopic treatment in colonic diverticular bleeding. J Gastroenterol Hepatol.
2020 May;35(5):815-820. doi: 10.1111/jgh.14901. Epub 2019 Dec 9. PMID: 31677183; PMCID:
PMC7318164.
Ochi T, Bianchini G, Ando M, Nozaki F, Kobayashi D, Criscitiello C, Curigliano G, Iwamoto T,
Niikura N, Takei H, Yoshida A, Takei J, Suzuki K, Yamauchi H, Hayashi N. Predictive andprognostic value of stromal tumour-infiltrating lymphocytes before and after neoadjuvant
therapy in triple negative and HER2-positive breast cancer. Eur J Cancer. 2019 Sep;118:41-48.
doi: 10.1016/j.ejca.2019.05.014. Epub 2019 Jul 11. PMID: 31302586.
Kameoka J, Kikukawa M, Kobayashi D, Okubo T, Ishii S, Kagaya Y. A Medical Record PeerReview System to Evaluate Residents' Clinical Competence: Criterion Validity Analysis. Tohoku
J Exp Med. 2019 Aug;248(4):253-260. doi: 10.1620/tjem.248.253. PMID: 31434837.
Saito Y, Noto H, Takahashi O, Kobayashi D. Visit-to-Visit Hemoglobin A1c Variability Is
Associated With Later Cancer Development in Patients With Diabetes Mellitus. Cancer J. 2019
Jul/Aug;25(4):237-240. doi: 10.1097/PPO.0000000000000387. PMID: 31335385.
Hirano K, Kobayashi D, Kohtani N, Uemura Y, Ohashi Y, Komatsu Y, Yanagita M, Hishida A.
Optimal follow-up intervals for different stages of chronic kidney disease: a prospective
observational study. Clin Exp Nephrol. 2019 May;23(5):613-620. doi: 10.1007/s10157-01801684-4. Epub 2019 Jan 28. PMID: 30687877; PMCID: PMC6469834.
Namura M, Tsunoda H, Kobayashi D, Enokido K, Yoshida A, Watanabe T, Suzuki K, Nakamura
S, Yamauchi H, Hayashi N. The Loss of Lymph Node Metastases After Neoadjuvant
Chemotherapy in Patients With Cytology-proven Axillary Node-positive Primary BreastCancer. Clin Breast Cancer. 2019 Aug;19(4):278-285. doi: 10.1016/j.clbc.2019.03.001. Epub
2019 Mar 11. PMID: 30975473.
Numata K, Shiga T, Omura K, Umibe A, Hiraoka E, Yamanaka S, Azuma H, Yamada Y,

Kobayashi D. Comparison of acute vertigo diagnosis and treatment practices between
otolaryngologists and non-otolaryngologists: A multicenter scenario-based survey. PLoS One.
2019 Mar 7;14(3):e0213196. doi: 10.1371/journal.pone.0213196. PMID: 30845218; PMCID:PMC6405109.