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ISSX to Bestow Society's Highest Honors to Yuichi Sugiyama,
Ph.D. and Robert Hanzlik, Ph.D. at 10th International Meeting
Links:
Register for the 10th International Meeting
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The R.T. Williams Distinguished Scientific Achievement Award
Sponsored by Charles Crespi and Family
The 2013 R.T. Williams Distinguished Scientific Achievement
Award is presented to an ISSX member or non-member fromany region that has made substantial and seminal scientificcontributions to the field over a sustained period. The focusof this award is the individual's scientific accomplishments
and it is intended to recognize the best in the field,internationally. The 2013 recipient is Yuichi Sugiyama,Ph.D., Head of the Sugiyama Laboratory, RIKEN Innovation
Center, Research Cluster for Innovation, in Yokohama,
Kanagawa, Japan.
Professor Sugiyama is a world leader in drug transporter and pharmacokinetic
studies, focusing on how drugs behave in the body and how they exert theirpharmacological and/or toxic effects. His work is firmly based on quantitative
principles whereby drugs are absorbed, reach their target tissue, are metabolized,and eventually secreted and how they interact with their receptors and exert apharmacological effect. A central goal of his research is to establish reliable andapplicable predictions of drug action in vivo, thereby optimizing drug therapy.
Professor Sugiyama integrated physiological, molecular, and genetic studies withpharmacokinetics and created a new research area - Molecular Pharmacokinetics.
We now understand how drugs interact with multiple components in the body,including lipid membranes and numerous proteins such as receptors, enzymes, andtransporters. Thus, a physiologically-based molecular pharmacokinetic model takes
into consideration all relevant processes in the body. Professor Sugiyama’s passion
is to dissect a majority of these processes by in vitro studies to allow one to predicta drug’s behavior in the body. His work has succeeded to a degree unmatched byany other laboratory.
Professor Sugiyama’s work has highlighted the importance of considering
pharmacokinetic properties in drug development, using good screening methods totest large numbers of drug candidates. Overall, he has produced a remarkable bodyof scientific work, with a profound impact on how we understand thepharmacokinetics, pharmacodynamics and use of drugs.
Professor Sugiyama has been actively involved in professional organizations for

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decades. Notably, he served as a Councilor of ISSX from 1998 – 2003 and waselected President-Elect in 2004. He then served as president of ISSX 2006-2007
while concurrently serving as the President of JSSX. He was Chair of thePharmaceutical Sciences World Conference in Kyoto in 2004, and has served asco-chair of a multitude of highly regarded international symposia over the years.
To recognize and celebrate Professor Sugiyama’s substantial and sustained scientificcontributions to the field of xenobiotic disposition spanning almost four decades, heis awarded the 2013 R.T. Williams Distinguished Scientific Achievement Award.
Award Presentation and Lecture: Monday, September 30
11:00 AM – 12:30 PM | FRONTENACThe Frederick J. Di Carlo Distinguished Service AwardThe 2013 Frederick J. Di Carlo Distinguished Service Awardis presented to an ISSX member from any region with anillustrious record of important service to the Society and its
goals. The 2013 recipient is Robert P. Hanzlik, Ph.D.
Professor Hanzlik has a history of service to ISSX and its
goals. A charter member of the Society, Professor Hanzlik
helped establish what has become the premier association
for academic and industrial researchers in this area. In theearly years he worked diligently to advance ISSX by serving
in leadership and service roles including Councilor (1984-1987) and as the firstchairman of the Scientific Affairs Committee (1986-1987). He was active inorganizing meetings, serving as the program co-chairman for the very first ISSX
North American Symposium (1985) and organizing and presenting a short course
titled "Reactive Metabolite Chemistry for Toxicologists” at the 2nd North American
ISSX Meeting in Florida, organized by Fred Di Carlo and Richard Welch (1987).
During the early 1990’s as ISSX grew, Professor Hanzlik’s steady hand andattention to detail significantly contributed to both the ISSX Bylaws Committee(1991) and the Publications Committee (1991-1995). Professor Hanzlik has alsoorganized several successful symposia and short courses for ISSX (6th NorthAmerican ISSX Meeting in North Carolina in 1994) and Program Committee
member for the 4th International ISSX Meeting in Seattle (1995). Professor Hanzlik
then accepted the highest levels of ISSX leadership and responsibility as ISSX
president-elect (1994 and 1995), president (1996-1997) and past president (1998-1999), providing a well-organized and strong leadership vision.
In addition to his record of outstanding support and leadership to ISSX, Professor
Hanzlik brings honor to ISSX as a distinguished scientist with an international
reputation and as a leading trainer of more than 50 graduate students andpost-doctoral fellows who now occupy positions in the pharmaceutical industry,
non-profit organizations, and academia. He has published in excess of 150 scientificpapers and has served as a member of editorial and advisory boards for several
prestigious scientific journals.
For his involvement, leadership, expertise, contributions, and commitment, ISSX is
proud to honor Professor Robert P. Hanzlik with the 2013 Frederick J. Di Carlo
Distinguished Service Award.
Award Presentation: Monday, September 30
11:00 AM – 12:30 PM | FRONTENAC

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