北海道大学大学院理学研究院附属ゲノムダイナミクス研究センター໭ᾏ㐨኱Ꮫ ኱Ꮫ㝔⌮Ꮫ◊✲㝔㝃ᒓࢤࣀ࣒ࢲ࢖ࢼ࣑ࢡࢫ◊✲ࢭࣥࢱ࣮ ᴫせ
㸰㸮㸰㸮

概
要

Hokkaido University, Faculty of Science
Genome Dynamics Research Center2020 ᖺᗘᴫせࡢⓎ⾜࡟࠶ࡓࡗ࡚
 ᙜࢭࣥࢱ࣮ࡣࠊᖹᡂ  ᖺ  ᭶࡟ᐇ㦂⏕≀ඹྠ฼⏝㒊㛛ࠊື≀ᰁⰍయඹྠ฼⏝㒊㛛ࠊ㑇ఏᏊᐇ㦂ඹྠ฼⏝㒊㛛ࡢ  㒊㛛࡛ᵓᡂࡉࢀࡿᩍ⫱◊✲ඹྠ฼⏝᪋タ࡜ࡋ࡚Ⓨ㊊ࡋࡲࡋࡓࠋྛ㒊㛛ࡣྛࠎࠊᪧᐇ㦂⏕≀ࢭࣥࢱ࣮ࠊᪧ⌮Ꮫ㒊㝃ᒓື≀ᰁⰍయ◊✲᪋タࠊᪧ㑇ఏᏊᐇ㦂᪋タ࠿ࡽᨵ⤌ࡉࢀ࡚ࡁࡓṔྐࢆࡶࡗ࡚࠾ࡾࠊ⌧ᅾࡢᙜࢭࣥࢱ࣮ࡢ୺࡞άື࡜ࡋ࡚ࠊ㏆஺⣔ࣛࢵࢺ࣭࣐
࢘ࢫࡢ⣔⤫ಖᏑࠊ⏕≀⣔ᐇ㦂ᐊ࣭㣫⫱ᐊ࣭ᐇ㦂ᶵჾ㢮ࡢ⥔ᣢ⟶⌮࡜฼⏝⪅࡬ࡢᥦ౪࡞࡝ࠊᚑ
᮶ࡢᶵ⬟ࢆ⏕࠿ࡋࡓᨭ᥼஦ᴗࢆ㐍ࡵ࡚࠸ࡲࡍࠋࡲࡓࠊᙜࢭࣥࢱ࣮ࡢ඲ᩍဨࡀ኱Ꮫ㝔⌮Ꮫ◊✲㝔⏕≀⛉Ꮫ㒊㛛࡟ᡤᒓࡋࠊࡑࡢᩍ⫱◊✲࡜ᙜࢭࣥࢱ࣮ࡢ㐠Ⴀࢆවᢸࡋ࡚⾜ࡗ࡚࠸ࡲࡍࠋᘓ≀⮬యࡣᪧ᪋タࢆ౑⏝ࡋ࡚࠸ࡿࡓࡵࠊᐇ㦂⏕≀ඹྠ฼⏝㒊㛛ࡣࢭࣥࢱ࣮ᮾᲷࠊࡑࡢ௚ࡢ  㒊㛛ࡣࢭࣥࢱ࣮すᲷࡢ  ࢝ᡤ࡟ศ࠿ࢀ࡚◊✲ᨭ᥼άືࢆ⾜ࡗ࡚࠸ࡲࡍࡀࠊ௒ᚋࡢࡼࡾຠ⋡ⓗ࡞ࢭࣥࢱ࣮㐠Ⴀࡢࡓࡵ࡟ࠊ୍య໬ࡋࡓᘓ≀࡜ᶵ⬟ࢆᵓ⠏ࡋ࡚⾜ࡁࡓ࠸࡜࠸࠺ᑗ᮶ᵓ᝿ࡀ࠶ࡾࡲࡍࠋ
 ࡉࡽ࡟ࠊᩥ㒊⛉Ꮫ┬ࡢࢧ࣏࣮ࢺ࡟ࡼࡾࠊ᪥ᮏ඲ᅜࡢ◊✲ᶵ㛵࡟ಖ⟶ࡉࢀ࡚࠸ࡿ㈗㔜࡞⏕≀㑇ఏ㈨※ࢆ⅏ᐖ࡟ࡼࡿᦆኻ࠿ࡽᏲࡿࡓࡵࠊ኱Ꮫ㐃ᦠࣂ࢖࢜ࣂࢵࢡ࢔ࢵࣉࣉࣟࢪ࢙ࢡࢺ㸦,%%3㸧ࡀ㐍ࡵࡽࢀ࡚࠾ࡾࠊᙜࢭࣥࢱ࣮ࡣ඲ᅜ࡟  ࡘ࠶ࡿ኱Ꮫࢧࢸࣛ࢖ࢺᣐⅬࡢ  ࡘ࡜ࡋ࡚ࡶࡑࡢ㔜せ࡞ᙺ๭ࢆᢸࡗ࡚࠸ࡲࡍࠋᖹᡂ  ᖺ  ᭶࡟㉳ࡁࡓᮾ᪥ᮏ኱㟈⅏࡟ࡼࡾࠊከࡃࡢ◊✲ᶵ㛵࡛⏕≀ᮦᩱ࣭㑇ఏ㈨※ࡀኻࢃࢀ◊✲ࡢ⥅⥆࡟ᨭ㞀ࢆࡁࡓࡋࡲࡋࡓࠋ,%%3 ࡣ෌ࡧࡇࡢࡼ࠺࡞ࡇ
࡜ࡀ㉳ࡇࡿ࡜ᡃࡀᅜࡢᅜ㝿ⓗ➇தຊ࡟ࡶᝏᙳ㡪ࢆ୚࠼࠿ࡡ࡞࠸࡜ࡢ༴᝹࠿ࡽࠊឡ▱┴ᒸᓮᕷࡢᇶ♏⏕≀Ꮫ◊✲ᡤࢆ୰᰾ᣐⅬ࡜ࡋ࡚㛤ጞࡉࢀࡓࣉࣟࢪ࢙ࢡࢺ࡛ࡍࠋ ࡲࡓࠊࡈᢎ▱ࡢࡼ࠺࡟ᖹᡂ  ᖺ  ᭶  ᪥ࡢ໭ᾏ㐨⫹᣺ᮾ㒊ᆅ㟈࡟ࡼࡾᮏᏛ࡛ࡶ኱つᶍ೵㟁ࡀⓎ⏕ࡋࠊ኱ࡁ࡞⿕ᐖࢆࡶࡓࡽࡋࡲࡋࡓࠋᙜࢭࣥࢱ࣮࡛ࡣࠊࡇࡢࡼ࠺࡞኱つᶍ⮬↛⅏ᐖ࡟ᑐࡍࡿᏳᐃࡋࡓᩍ⫱◊✲⎔ቃࢆᣢ⥆ⓗ࡟ᥦ౪ࡍࡿࡓࡵࡢᨭ᥼⤌⧊࡜ࡋ࡚ࠊࡑࡢ౯್ࡀ୍ᒙ㧗ࡲࡗ࡚ࡁ࡚࠸ࡲࡍࠋࡇࢀ࡟క࠸ࠊᮏᖺᗘࡼࡾ  ᖺ࠿ࡅ࡚ᮏࢭࣥࢱ࣮୧Ჷࡢᨵಟᕤ஦ࡀᐇ᪋ࡉ
ࢀࡿ㐠ࡧ࡜࡞ࡾࡲࡋࡓࠋ⌧ᅾࡣᘓ≀ࡢᨵಟࡸᐇ㦂⏕≀ࡢ⛣㌿➼ࡢィ⏬❧᱌ࢆ㐍ࡵ࡚࠾ࡾࡲࡍࠋ ௒ᚋࡶᩍ⫱◊✲ࡢඹྠ฼⏝᪋タ࡜ࡋ࡚ࠊ฼⏝౯್ࡢ㧗࠸ᨭ᥼ࡢᥦ౪࡟ດࡵ࡚⾜ࡁࡲࡍࡢ࡛ࠊ
ࡈ⌮ゎ࡜ࡈ༠ຊࡢ⛬ࠊࡼࢁࡋࡃ࠾㢪࠸⏦ࡋୖࡆࡲࡍࠋ                 ௧࿴  ᖺ  ᭶                 ኱Ꮫ㝔⌮Ꮫ◊✲㝔                      㝃ᒓࢤࣀ࣒ࢲ࢖ࢼ࣑ࢡࢫ◊✲ࢭࣥࢱ࣮㛗                                   ᒣཱྀ ῟஧

┠ ḟ

・

２０２０年度概要の発行にあたって・センター教職員・運営委員一覧、平成 30 年度活動報告

Ｐ １

・

実験生物共同利用部門運営状況

Ｐ ３・

遺伝子実験共同利用部門・動物染色体共同利用部門運営状況

Ｐ ３１

・

添付資料

Ｐ ３９

䝀䝜䝮䝎䜲䝘䝭䜽䝇◊✲䝉䞁䝍䞊䚷ᩍ⫋ဨ䝉䞁䝍䞊㛗䚷
㻌㻌ᩍ䚷㻌ᤵ䚷䚷㻌㻌㻌㻌㻌㻌ᐇ㦂⏕≀ඹྠ฼⏝㒊㛛 㻌㻌෸ᩍᤵ䚷䚷㻌㻌෸ᩍᤵ䚷䚷
㻌㻌ຓ㻌䚷ᡭ

໭⏣䚷୍༤
ຍ⸨䚷ᚭ
ฟཱྀ䚷ၿ⾜

㑇ఏᏊᐇ㦂ඹྠ฼⏝㒊㛛㻌㻌ᩍ㻌䚷ᤵቑ⏣䚷㝯୍ື≀ᰁⰍయඹྠ฼⏝㒊㛛㻌㻌ຓ㻌䚷ᩍྜྷ⏣䚷㑳ஓ㻌㻌ᢏ⾡ᑓ㛛⫋ဨ㻌㻌◊✲ᨭ᥼᥎㐍ဨ㻌㻌஦ົ⿵ຓဨ

ᑠ㔪䚷ᕸᐇᏊ㻌䠄ᮾᲷ䠅ᑠᆏ䚷䛒䜖䜏㻌䠄すᲷ䠅ᒸᮧ䚷ᰤ⌮䚷㻌㻌䠄すᲷ䠅㻌㻌㻌㻌㻌㻌㻌㻌㻌㻌㻌㻌㻌㻌㻌㻌㻌䝉䞁䝍䞊⫋ဨ
㻌㻌

ᒣཱྀ䚷῟஧

䝀䝜䝮䝎䜲䝘䝭䜽䝇◊✲䝉䞁䝍䞊㐠Ⴀጤဨ఍ጤဨ㛗 㻌㻌㻌㻌Ọ஭䚷㝯ဢ㻌㻌㻌㻌ቑ⏣䚷㝯୍䚷㻌㻌㻌㻌ຍ⸨䚷ᚭ㻌㻌㻌㻌໭⏣䚷୍༤㻌㻌㻌㻌ຍ⸨䚷ᩔஅ㻌㻌㻌㻌㯮ᒾ䚷㯞㔛㻌㻌㻌㻌ᑠட䚷୍ᘯ䚷䚷⸨⏣䚷▱㐨䚷䚷ỈἼ䚷ㄔ
㻌㻌㻌㻌㈗ᓥ䚷♸἞㻌㻌㻌㻌ᕝཎ䚷Ꮫᩍ㻌䚷ᤵ㻌㻌㻌㻌㻌㻌⌮Ꮫ◊✲㝔ᩍ㻌䚷ᤵ㻌㻌㻌㻌㻌㻌⌮Ꮫ◊✲㝔෸ᩍᤵ㻌㻌㻌㻌㻌㻌⌮Ꮫ◊✲㝔෸ᩍᤵ㻌㻌㻌㻌㻌㻌⌮Ꮫ◊✲㝔ᩍ㻌䚷ᤵ㻌㻌㻌㻌㻌㻌⌮Ꮫ◊✲㝔ᩍ㻌䚷ᤵ㻌㻌㻌㻌㻌㻌⌮Ꮫ◊✲㝔ᩍ㻌䚷ᤵ㻌㻌㻌㻌㻌㻌⌮Ꮫ◊✲㝔ᩍ㻌䚷ᤵ㻌㻌㻌㻌㻌㻌⌮Ꮫ◊✲㝔ᩍ㻌䚷ᤵ㻌㻌㻌㻌㻌㻌⌮Ꮫ◊✲㝔ᩍ㻌䚷ᤵ㻌㻌㻌㻌㻌㻌㎰Ꮫ◊✲㝔෸ᩍᤵ㻌㻌㻌㻌㻌㻌㎰Ꮫ◊✲㝔௧࿴ඖᖺᗘ㻌㻌άືሗ࿌䞉㻌ᴫせ㻌㻞㻜㻝㻥㻌䠄㻌ᖺḟሗ࿌㻌䠅㻌㻌Ⓨ⾜㻌䠄㻌㻤᭶㻌䠅䞉㻌㐠Ⴀጤဨ఍㛤ദ㻌䠄㻌㻢᭶䞉㻤᭶䞉㻝㻞᭶䚷ィ㻟ᅇ㻌䠅䞉㻌ᐇ㦂⏕≀ඹྠ฼⏝㒊㛛㻌᪂つ฼⏝⪅ㅮ⩦఍㛤ദ㻌䠄㻌㻠᭶䞉㻡᭶䞉㻢᭶䞉㻝㻜᭶䚷ィ㻢ᅇ㻌䠅

−1−

ᮾᲷ

ᐇ㦂⏕≀ඹྠ฼⏝㒊㛛

−3−

ᐇ 㦂⏕
⏕ ≀ඹ
ඹ ྠ฼⏝㒊㛛ᙜ㒊㛛ࡣࠊ࣐࢘ࢫࠊࣛࢵࢺࠊ࢘ࢧࢠࠊࣔࣝࣔࢵࢺࡢ့ஙື≀࡟ຍ࠼ࠊ࢟ࣥ࢝ࢳࣙ࢘
ࡸ࢘ࢬࣛ➼ࡢ㫽㢮ࠊ࣓ࢲ࢝➼ࡢ㨶㢮ࠊ࢖࢝࡜࠸ࡗࡓᾏ⏘ࡢ↓⬨᳝ື≀ࠊࢥ࢜ࣟࢠࡸࢦ
࢟ࣈࣜ➼ࡢ᪻⹸ࠊࡲࡓࢩࣟ࢖ࢾࢼࢬࢼ➼ࡢᐇ㦂᳜≀࠿ࡽࠊ㔝እ᥇ྲྀࡋ࡚ࡁࡓ᳜≀ࠊࡉࡽ࡟ᶞᮌ࡟⮳ࡿࡲ࡛ࠊᵝࠎ࡞⏕≀✀ࢆ㣫⫱࣭᱂ᇵ࡛ࡁࡿࡼ࠺ᩚഛࢆ⾜ࡗ࡚࠸ࡿඹྠ฼⏝᪋タ࡛ࡍࠋ㏆ᖺࡣࠊ࣐࢘ࢫࠊࣛࢵࢺࡢࡳ࡞ࡽࡎࠊࢥ࢜ࣟࢠ࡟࠾࠸࡚ࡶ㑇ఏᏊᨵኚື
≀ࡀ㣫㣴ࡉࢀ࡚࠾ࡾࠊἲ࡟‽ᣐࡋࡓ㣫⫱タഛࡢᩚഛ࡟ࡶᚰࡀࡅ࡚࠾ࡾࡲࡍࠋࡇࢀࡽࡢ
ඹྠ฼⏝࡟ຍ࠼ࠊ࣐࢘ࢫ࡜ࣛࢵࢺࡢ㏆஺⣔ࡢ⥔ᣢ஦ᴗࡶ⾜ࡗ࡚࠾ࡾࡲࡍࠋᮏ᪋タࡢ❹ᕤࡣ᫛࿴  ᖺ࡛࠶ࡾࠊࡍ࡛࡟⠏  ᖺࢆ⤒㐣ࡋ࡚࠾ࡾࡲࡍࠋᖾ࠸ᮏᖺᗘ
࡟࠾ࡁࡲࡋ࡚ࠊᨵಟᕤ஦࡟ಀࡿᴫ⟬せồࢆᩥ㒊⛉Ꮫ┬࡟⾜ࡗࡓ࡜ࡇࢁࠊ௧࿴  ᖺᗘ࠾ࡼࡧ  ᖺᗘࡢ  ᖺ㛫࡟ࢃࡓࡿண⟬ࡢෆ♧ࢆ࠸ࡓࡔࡃࡇ࡜ࡀ࡛ࡁࡲࡋࡓࠋࡇࢀࡶ㛵ಀྛᡤࡢከ኱࡞ࡈຓຊࡀ࠶ࡗࡓ࠿ࡽࡇࡑ࡛࠶ࡾࠊࡈᨭ᥼ࢆ࠸ࡓࡔࡁࡲࡋࡓࡇ࡜࡟ឤㅰ⏦ࡋୖࡆࡲࡍࠋ௒ᚋ  ᖺᚋࡢᑗ᮶ࡶ຺᱌ࡋ࡞ࡀࡽࠊᐇ㦂⏕≀ࡢ㣫⫱࣭᱂ᇵࡀࡼࡾ෇⁥࡟ᐇ᪋࡛ࡁࡿ
ࡼ࠺ࠊ᪋タࡢタィࢆ㗦ព㐍ࡵ࡚࠸ࡿ࡜ࡇࢁ࡛ࡍࠋࡲࡓࠊᨵಟᕤ஦ࡢᮇ㛫୰࡟ࡣࠊ⌧ᅾ㣫⫱࣭᱂ᇵࡉࢀ࡚࠸ࡿᐇ㦂⏕≀ࡢ௬⛣㌿ࡀᚲ㡲࡜࡞ࡾࡲࡍࠋ௬⛣㌿ᮇ㛫୰ࡶ⁫ࡾ࡞ࡃ◊✲άືࡢᐇ᪋ࡀ⾜࠼ࡿࡼ࠺ࠊࡇࡢ⛣㌿࡟ࡘࡁࡲࡋ࡚ࡶ‽ഛࡋ࡚࠸ࡿ࡜ࡇࢁ࡛ࡍࠋ฼
⏝⪅ࡢ᪉ࠎ࡟࠾࠿ࢀࡲࡋ࡚ࡶࠊఱ༞ࠊࡈ༠ຊࢆࡼࢁࡋࡃ࠾㢪࠸࠸ࡓࡋࡲࡍࠋ
௒ᚋ࡜ࡶ◊✲⎔ቃࡢྥୖ࡜⥔ᣢࢆ┠ᣦࡋ࡚ࠊ◊✲ཬࡧᐇ㦂ࡢሙࢆᥦ౪ࡋ࡚࠸ࡃດຊ
ࢆ⥆ࡅ࡚ࡲ࠸ࡾࡲࡍࠋ௧ ࿴ඖᖺᖺ ᗘ  ᐇ 㦂⏕⏕ ≀ඹඹྠ฼⏝㒊㛛 ฼ ⏝≧ἣ ᡤ ᒓ ฼ ⏝⪅ᩘᩘᩥᏛ◊✲㝔

㸯ᆅ⌫⎔ቃ⛉Ꮫ◊✲㝔㸱⌮Ꮫ◊✲㝔

㸯㸵

㎰Ꮫ◊✲㝔

㸰ᩍ⫱Ꮫ◊✲㝔㸯ᕤᏛ◊✲㝔

㸰་Ꮫ◊✲㝔㸯㟁Ꮚ⛉Ꮫ◊✲ᡤ㸯໭᪉⏕≀ᅪࣇ࢕࣮ࣝࢻ⛉Ꮫࢭࣥࢱ࣮

㸯⥲ྜ༤≀㤋

㸯᝟ሗ⛉Ꮫ◊✲㝔

㸯

ィ

㸱㸯 



−4−

௧࿴ඖᖺᗘ฼⏝⪅䛾ෆヂ㟁Ꮚ◊㻘㻌㻝 ໭᪉䢈䡤䡬䢕䢀䢚㻘㻌㻝᝟ሗ⛉Ꮫ㻘㻌㻝

ᾏỈ㻘㻌㻢့ங㢮䞉㫽㢮
㻝㻜

ᩍ⫱㻘㻌㻝
ᩥ㻘㻌㻝
⣧Ỉ㻘㻌㻠

༤≀㤋㻘㻌㻝

⌮㻘㻌㻝㻣

་㻘㻌㻝
ᕤ㻘㻌㻞

Ỉ⏕ື≀㻘㻌㻟
᪻⹸㻘㻌㻠

㎰㻘㻌㻞

᳜≀㻘㻌㻠

ᆅ⌫⎔ቃ㻘㻌㻟
฼⏝⏦ㄳ⪅ᡤᒓ㒊ᒁ
41

H24

38

H25

ᢅ䛳䛶䛔䜛⏕≀ཬ䜃Ỉ➼฼⏝䛾⏦ㄳᩘ

41
36

H26

H27

34

H28

30

31

31

H29

H30

R1

฼⏝⏦ㄳᩘ᥎⛣⣔⤫ಖᏑ䝸䝇䝖
䝬䜴䝇䠄㻤⣔⤫䠅㻮㻭㻸㻮㻛㼏
㻮㻭㻸㻮㻛㼏㻭㼚
㻮㻷㻴㻯㻮㻭㻯㻮㻭㻛㻴㻙㼀㻢
㻯㻡㻣㻮㻸㻛㻢
㻯㻟㻴
㻸㼀㻛㻿䡒

−5−

䝷䝑䝖䠄㻝㻝⣔⤫䠅㻭㻯㻵㻭㻯㻵㻔㻿㻕
㻭㻸㻮
㻮㻺
㻷㼅㻺
㻸㻱㻭
㻸㻱㻶
㻺㻵㻳㻙䊢
㻿㻰㻶
㼀㻻
㼃㻷㻭㻴

䚷

௧࿴ඖᖺᗘ㻌ᐇ㦂⏕≀ඹྠ฼⏝㒊㛛䚷ಖᏲႠ⧋䝸䝇䝖

ᖹᡂ㻟㻝ᖺ

㻠᭶

௧࿴ඖᖺ

㻡᭶

ᐊไᚚ┙䝍䜲䝮䝇䜲䝑䝏ྲྀ᭰ᕤ஦㻢᭶㻞㝵ᐇ㦂ᐊ㻔㻤㻕᥮Ẽᡪ᧔ཤᕤ஦

㻣᭶㻞㝵ᑠ⏕≀㣫⫱ᐊ㻔㻡㻕䜶䜰䝁䞁ಟ⌮䝥䝺䝣䜱䝹䝍䞊஺᥮㻤᭶㻝㝵Ὑίᐊᾘẘჾᛶ⬟᳨ᰝᩚഛ䠄䜸䞊䝖䜽䝺䞊䝤䠅㻞㝵ᐇ㦂ᐊ㻔㻡㻕䜶䜰䝁䞁ᐊෆᶵὙίసᴗ
㠀ᖖ⏝Ⓨ㟁ᶵ⡆᫆Ⅼ᳨㞀ᐖᶞᮌᯞᡶ䛔సᴗ

㻥᭶

௧࿴㻞ᖺ

ᐃᮇΎᤲ㻔ẖ᭶䠅⎔ቃ⾨⏕⟶⌮Ⅼ᳨䠄ẖ᭶䠅ᶞᮌ෤ᅖ䛔እ䛧ᴗົᐊෆ䝗䜰䝟䝛䝹ྲྀ௜௚ᕤ஦

㻝㻞᭶ᶵᲔᐊෆ⵨Ẽ㓄⟶ಟ⌮ᶞᮌ෤ᅖ䛔ᴗົ

㻞᭶ᅡሙ㧗ᮌ㑅ᐃసᴗ

−6−௧࿴ඖᖺᗘ䚷䝀䝜䝮䝎䜲䝘䝭䜽䝇◊✲䝉䞁䝍䞊䚷฼⏝⪅◊✲ㄢ㢟䠄ᐇ㦂⏕≀ඹྠ฼⏝㒊㛛䠅ᡤ㻌㻌ᒓ㒊㻌㻌㛛㻌㻌䞉㻌㻌ศ㻌㻌㔝㻌㻌㻌➼⫋㻌ྡᆅ⌫⎔ቃ⛉Ꮫ
◊✲㝔ᆅ⌫⎔ቃ⛉Ꮫ
◊✲㝔ᆅ⌫⎔ቃ⛉Ꮫ
◊✲㝔⤫ྜ⎔ቃ⛉Ꮫ䞉⮬↛⎔ቃಖ඲ᩍ㻌ᤵ㟢ᓮ㻌㻌ྐᮁ 䚷ⅆᒣ䛻䛚䛡䜛ᇙᅵ✀Ꮚ㞟ᅋ䛾ᐃ㔞䛚䜘䜃⏕⫱ᐇ㦂⤫ྜ⎔ቃ⛉Ꮫ䞉⎔ቃ㐺ᛂ⛉Ꮫᩍ㻌ᤵἈ㔝㻌㻌㱟ᩥ 䚷ᾏ⏘⸴㢮䛾஧ḟ௦ㅰ⏘≀䛻㛵䛩䜛◊✲⎔ቃ⏕≀⛉Ꮫ䞉㝣ᇦ⏕ែᏛ

෸ᩍᤵ

ᕤ⸨䚷ᓅ

⌮Ꮫ◊✲㝔

≀⌮Ꮫ䞉㔞Ꮚ≀⌮Ꮫ෸ᩍᤵᯇỌ㻌㻌ᝅ᫂ 䚷᭷ᶵᑟయ䛻䛚䛡䜛≀ᛶ⌮Ꮫ◊✲㝔≀⌮Ꮫ䞉㟁Ꮚ≀ᛶ≀⌮Ꮫᩍ㻌ᤵἙᮏ㻌㻌඘ྖ 䚷ศᏊᛶᑟయ䛾ྜᡂ⌮Ꮫ◊✲㝔⏕≀⛉Ꮫ䞉ᙧែᶵ⬟Ꮫᩍ㻌ᤵᒣཱྀ㻌㻌῟஧ 䚷㧗➼᳜≀䛾ᶵ⬟Ⓨ⌧䞉⎔ቃᛂ⟅ไᚚᶵᵓ⌮Ꮫ◊✲㝔⏕≀⛉Ꮫ䞉⾜ື⚄⤒⏕≀Ꮫᩍ㻌ᤵᑠᕝ㻌㻌ᏹே 䚷䝣䝍䝩䝅䝁䜸䝻䜼䛾⚄⤒⾜ືᏛⓗ◊✲⌮Ꮫ◊✲㝔⏕≀⛉Ꮫ䞉⾜ື⚄⤒⏕≀Ꮫ

ᩍ㻌ᤵ

ỈἼ㻌㻌ㄔ

⌮Ꮫ◊✲㝔

⏕≀⛉Ꮫ䞉⾜ື⚄⤒⏕≀Ꮫ෸ᩍᤵ໭⏣㻌㻌୍༤ 䚷᪂䛯䛺⑓ែ䝰䝕䝹ື≀䛾సฟ䛸ཎᅉ㑇ఏᏊ䛾ྠᐃ⌮Ꮫ◊✲㝔⏕≀⛉Ꮫ䞉⾜ື⚄⤒⏕≀Ꮫ෸ᩍᤵ⏣୰㻌㻌ᬸ᫂ 䚷䝠䝯䜲䜹䛾⥅௦㣫⫱ᢏ⾡䛾㛤Ⓨ⌮Ꮫ◊✲㝔⏕≀⛉Ꮫ䞉⾜ື⚄⤒⏕≀Ꮫ෸ᩍᤵ࿴ከ㻌㻌࿴ᏹ 䚷㬆⚺㢮䜢⏝䛔䛯ⓎኌᏛ⩦䞉⏕ᡂ䛸䛭䛾⬻ෆศᏊᶵᵓ⌮Ꮫ◊✲㝔⏕≀⛉Ꮫ䞉⏕ṪⓎ⏕⏕≀Ꮫᩍ㻌ᤵ㯮ᒾ䚷㯞㔛 㻌㻌့ங㢮䛚䜘䜃㫽㢮䛻䛚䛡䜛ᛶỴᐃ䞉ཷ⢭䛻㛵䜟䜛ศᏊ䝯䜹䝙䝈䝮䛾ゎ᫂⌮Ꮫ◊✲㝔⏕≀⛉Ꮫ䞉⏕ṪⓎ⏕⏕≀Ꮫᩍ㻌ᤵᒣୗ㻌㻌ṇව 䚷⬨᳝ື≀䛻䛚䛡䜛⏕Ṫ⣽⬊ᙧᡂ䛾ไᚚᶵᵓ⌮Ꮫ◊✲㝔⏕≀⛉Ꮫ䞉⏕ṪⓎ⏕⏕≀Ꮫ෸ᩍᤵⲶཎ㻌㻌ඞ┈ 䚷⬨᳝ື≀䛾⏕Ṫᶵ⬟䛻㛵䛩䜛◊✲⌮Ꮫ◊✲㝔⏕≀⛉Ꮫ䞉⏕ṪⓎ⏕⏕≀Ꮫ

෸ᩍᤵ

ᮌᮧ㻌㻌ᩔ

⌮Ꮫ◊✲㝔

⏕≀⛉Ꮫ䞉⏕ṪⓎ⏕⏕≀Ꮫ෸ᩍᤵᑠ㇂㻌㻌཭ஓ 䚷༸ẕ⣽⬊ᙧᡂ䛸ึᮇⓎ⏕䛾ศᏊᶵᵓゎᯒ⌮Ꮫ◊✲㝔⏕≀⛉Ꮫ䞉ከᵝᛶ⏕≀Ꮫᩍ㻌ᤵᑠட㻌㻌୍ᘯ 䚷⸴㢮䛾⣔⤫㐍໬Ꮫ⌮Ꮫ◊✲㝔⏕≀⛉Ꮫ䞉ከᵝᛶ⏕≀Ꮫ

෸ᩍᤵ

᯳ཎ㻌㻌ᏹ

䚷ᾏ⏘↓⬨᳝ື≀䛾⣔⤫ศ㢮Ꮫⓗ◊✲⌮Ꮫ◊✲㝔⏕≀⛉Ꮫ䞉ከᵝᛶ⏕≀Ꮫ

෸ᩍᤵ

ຍ⸨㻌㻌ᚭ

䚷䝅䝵䜴䝆䝵䜴䝞䜶䛚䜘䜃᳜㣗ᛶ䝔䞁䝖䜴䛾㐍໬Ꮫⓗ◊✲⌮Ꮫ◊✲㝔⏕≀⛉Ꮫ䞉ከᵝᛶ⏕≀Ꮫㅮᖌゅ஭䚷ᩗ▱ 㻌㻌ᑠᆺ⏥Ẇ㢮䛾ᛶ䞉⏕Ṫᵝᘧ䛻㛵䛩䜛◊✲㎰Ꮫ◊✲㝔ᇶ┙◊✲䞉⏕≀㈨※⛉Ꮫᩍ㻌ᤵ⛅ඖ㻌㻌ಙ୍ 䚷䝃䝑䝫䝻䝣䜻䝞䝑䝍䛾㓄അ⾜ື䛸⏕Ṫ㝸㞳ᶵᵓ䛻㛵䛩䜛◊✲㎰Ꮫ◊✲㝔ᇶ┙◊✲䞉␆⏘⛉Ꮫ

෸ᩍᤵ

ᕝཎ㻌㻌Ꮫ

ᩍ⫱Ꮫ◊✲㝔

ᩍ⫱Ꮫ䞉೺ᗣయ⫱Ꮫ෸ᩍᤵ ᒣ௰䚷ຬ஧㑻 䚷㻌⏕≀᫬ィ䛻䜘䜛⾜ື䝸䝈䝮䛾ᨭ㓄ᵝᘧ䛸⾜ື䝸䝈䝮䛛䜙୰ᯡ᫬ィ䜈䛾䝣䜱䞊䝗䝞䝑䜽ᶵᵓ䛾ゎ᫂ᕤᏛ◊✲㝔ᛂ⏝≀⌮Ꮫ䞉㔞Ꮚ≀ᛶᕤᏛ

ᩍ㻌ᤵ

୹⏣㻌㻌⪽

䚷పḟඖᑟయ䛾㟁Ꮚ≧ែ䛾◊✲ᕤᏛ◊✲㝔䡰䢄䢕䡳䢚䡬⎔ቃ䡸䡹䡿䢍䞉ᛂ⏝䡰䢄䢕䡳䢚䡬䡸䡹䡿䢍

ᩍ㻌ᤵ

⏣㒊䚷㇏

䚷⇞ᩱ㟁ụෆỈศᣲືཬ䜃෾⤖⌧㇟䛾ྍど໬ほᐹ་Ꮫ◊✲㝔་ṑᏛ⥲ྜ◊✲Ჷ䞉୰ኸ◊✲㒊㛛ຓ㻌ᩍᒣ㔝㎶㻌㈗ಙ 㻌㻌⚄⤒⣔䛻䛚䛡䜛᝟ሗ䜻䝱䝸䜰䜢᫂䜙䛛䛻䛩䜛ᩥᏛ◊✲㝔ே㛫⛉Ꮫ䞉ᚰ⌮Ꮫᩍ㻌ᤵ࿴⏣㻌㻌༤⨾ 䚷䝷䝑䝖䛾㉸㡢ἼⓎኌ䛻ཬ䜌䛩Ỉ㓟໬㻼㻯㻮ཬ䜃㻼㻮㻰㻱䛾ᙳ㡪᝟ሗ⛉Ꮫ◊✲㝔 ⏕࿨ே㛫᝟ሗ⛉Ꮫ䞉䝞䜲䜸䜲䞁䝣䜷䝬䝔䜱䜽䝇ᩍ㻌ᤵ㐲⸨䚷ಇᚨ 㻌㻌ศᏊ㐍໬ゎᯒ䛻䜘䜛䜰䝯䝸䜹䛾䝠䝵䜴䝍䞁䛾ఏ᧛⤒㊰䛾᥎ᐃ㟁Ꮚ⛉Ꮫ◊✲ᡤ 㝃ᒓ♫఍๰㐀ᩘᏛ◊✲䡺䢙䡼䡬䞉ே㛫ᩘ⌮◊✲෸ᩍᤵ㟷἟㻌㻌ோᚿ 䚷䜽䝻䝁䜸䝻䜼䛻䛚䛡䜛㐺ᛂ⾜ື䛾ᐇ᫬㛫ᛶ䜢ไᚚ䛩䜛⚄⤒ᶵᵓ䛾◊✲໭᪉⏕≀ᅪ䝣䜱䞊
⏕≀ከᵝᛶ㡿ᇦ䞉ᾏ⏘⸴㢮㐺ᛂᶵ⬟䝹䝗⛉Ꮫ䝉䞁䝍䞊

෸ᩍᤵᅄ䝒಴㻌඾⁠ 䚷䝁䞁䝤㢮䛻䛴䛔䛶䚸ᇵ㣴ಖᏑἲ䛾☜❧䛸✀ⱑసฟᢏ⾡䛾㛤Ⓨ෸ᩍᤵ㜿㒊㻌㻌๛ྐ 䚷⣚⸴䝋䝌ᒓ䛚䜘䜃㏆⦕ᒓ䛻㛵䛩䜛✀⏕≀Ꮫⓗ◊✲⥲ྜ༤≀㤋◊✲㒊䞉㈨ᩱᇶ♏◊✲⣔Ặ㻌㻌ྡ◊㻌㻌✲㻌㻌ㄢ㻌㻌㢟㻌㻌ྡ䚷䝬䝒䝶䜲䜾䝃ᒓ᳜≀䛾㏦⢊⏕ែᏛ䛻㛵䛩䜛◊✲ᐃ䚷᪻⹸䛾Ꮫ⩦䛾⚄⤒ᶵᵓ䚷့ங㢮䛾⏕Ṫ䛻䛛䛛䜟䜛䝀䝜䝮ᶵ⬟䛻㛵䛩䜛◊✲䚷䝬䜴䝇⬇యእ᧯స䛻䜘䜛ಶయⓎ⏕䛻㛵䛩䜛◊✲−7−Мဇ‫إ‬ԓᴾᴾ
ᆅ⌫⎔
⎔ቃ⛉Ꮫ◊
◊✲㝔
㝔
኱Ꮫ㝔ᆅ
⤫ྜ⎔
⎔ቃ⛉
⛉Ꮫ㒊㛛
 ⮬↛⎔ቃಖ඲ศ㔝㟢ᓮ ྐᮁ฼⏝⪅: ᱵᮧᫀᏹ࣭⠊ ⍞⌈ᐊ࡟࠾࠸࡚ࠊ(1)࣡ࢱࢫࢤ✀ᏊⓎⱆ≉ᛶ࠾ࡼࡧ㇂ෆᆓ୺ᙧᡂ㐣⛬࡟㛵ࡍࡿᐇ㦂࡜ࠊ(2)ᖐ໬᳜≀࡜ᅾ᮶✀ࡢྠᡤⓗ✀ᏊⓎⱆ㛵ࡍࡿᐇ㦂ࢆ⾜ࡗࡓࠋ(1) ࣡ࢱࢫࢤ✀ᏊⓎⱆ≉ᛶ࠾ࡼࡧ㇂ෆᆓ୺ᙧᡂ㐣⛬࡟㛵ࡍࡿᐇ㦂
࣡ࢱࢫࢤ(Eriophorum vaginatum L.)ࡣࠊ‵ཎ࡟࠾࠸࡚㇂ෆᆓ୺ࢆᙧᡂࡍࡿࡀࠊࡑࡢᙧᡂ㐣⛬࡟ࡣᗘ࣭㝆Ỉ㔞ࡀ㛵୚ࡍࡿ࡜࠸࠺௬ㄝࡀ࠶ࡿࡀࠊᆅᇦ
ᛶࡀㄆࡵࡽࢀ⤫୍ⓗ࡞ぢゎࡣᚓࡽࢀ࡚࠸࡞࠸ࠋࡑ
ࡇ࡛ࠊ࣡ࢱࢫࢤࡢ✀ᏊⓎⱆ≉ᛶࡢ᳨ฟ࠾ࡼࡧ㇂ෆ
ᆓ୺ᙧᡂึᮇẁ㝵ࢆ෌⌧ࡍࡿࡇ࡜ࢆ┠ⓗ࡟ࠊ ᐊ࡟࠾࠸࡚ᶍೌᐇ㦂ࢆ⾜ࡗࡓࠋ࡞࠾ࠊⓎⱆᐇ㦂࡟౪ࡋࡓ✀Ꮚࡣࠊࢧࣟ࣋ࢶ‵ཎἾⅣ᥇᥀㊧ᆅࡢ⛣᳜ᐇ㦂࡟ࡶ⏝࠸ࡓࠋ✀Ꮚࡣࠊ⤖ᐇᮇ࡟᥇᥀㊧ᆅ࠿ࡽ᥇ྲྀࡋࡓࠋࡇࢀࡽࡢ✀Ꮚࢆࠊ200 ✰(26 cm × 52 cm × 5
cm, ⦪࣭ᶓ࣭㧗ࡉ)ࡢࣉࣛࢫࢳࢵࢡᐜჾෆ࡟ཌࡉ 4
cm ࡜࡞ࡿࡼ࠺ἾⅣࢆධࢀࠊྛ✰࡟ 3 ⢏ࡎࡘ 2019
ᖺ 7 ᭶ 14 ᪥࡟᧛✀ࡋࠊⓎⱆᩘࢆグ㘓ࡋࡓࠋྜィ࡛
3600 ⢏ (200 ✰ × 3 ⢏ × 6 ཯᚟)ࢆ᧛✀ࡋ࡚࠸ࡿࠋ
ḟ࡟ࠊ18 cm × 58 cm × 15 cm ࡢࣉࣛࣥࢱ࣮ࢆ⏝ពࡋࠊࣂ࣮࣑࢟ࣗࣛ࢖ࢺࢆཌࡉ 7 cmࠊࡑࡢୖ࡟ἾⅣ
ࢆཌࡉ 2 cm ࡟ᩜࡁࠊ10 cm 㛫㝸࡛ 10 ࡢᐇ⏕ࢆ⛣᳜ࡋࡓࠋࣉࣛࣥࢱ࣮ࡣ 4 ࡘ‽ഛࡋࠊࡑࢀࡒࢀ࡟ࠊ᪋
⫧࣭┒ᅵฎ⌮ࠊ᪋⫧ฎ⌮ࠊ┒ᅵฎ⌮ࠊ↓ฎ⌮(ᑐ↷)ࡢ࠸ࡎࢀ࠿ࢆ᪋ࡋᡂ⫱ᐇ㦂ࢆ⾜ࡗࡓࠋ᪋⫧࣭┒ᅵࡣ᭱ึࡢ 2 ࠿᭶ࡣ㐌࡟ 1 ᗘࠊࡑࢀ௨㝆ࡣ᭶࡟ 1 ᗘ⛬ᗘ⾜࠸ࠊࡑࡢ㒔ᗘࠊᐇ⏕ࡢⴥࡢ᭱኱㛗࣭ᯛᩘࢆィ ࡋࡓࠋ
9 ᭶ 1 ᪥ࡲ࡛࡟ 589 ✀Ꮚ(Ⓨⱆ⋡ 16.4%)ࡀⓎⱆࡋࡓࠋࡇࢀࡽࡢ࠺ࡕࠊ460 ᐇ⏕ࢆㄪᰝ༊࡟⛣᳜ࡋࠊ⏕Ꮡ⋡࡜ᡂ㛗ࢆグ㘓୰࡛࠶ࡿࠋ࡞࠾ࠊᐇ⏕ᡂ㛗ࡣࠊ
2019 ᖺ 10 ᭶ୗ᪪࡟ࡣࠊ ᐊࡢ᪉ࡀⰋዲ࡛࠶ࡗࡓࠋ
ᐊᐇ㦂ࡣࠊ⥅⥆୰࡛࠶ࡿࠋ
(2) ᖐ໬᳜≀࡜ᅾ᮶✀ࡢྠᡤⓗ✀ᏊⓎⱆ㛵ࡍࡿᐇ㦂ᮏᐇ㦂ࡣࠊᙜึࡣᅵተᰤ㣴᮲௳ࡢ␗࡞ࡿ⎔ቃୗ࡛ᖐ໬᳜≀ࡀᅾ᮶✀ࡢᡂ㛗࡟୚࠼ࡿᙳ㡪ࢆᐃ㔞໬ࡍࡿ┠ⓗ࡛㛤ጞࡉࢀࡓࡀࠊᅾ᮶✀ࡢⓎⱆ⋡ࡀప࠸ࡓࡵࠊィ⏬ࢆኚ᭦ࡋࠊᅵተᰤ㣴ࡀᖐ໬᳜≀ࡢ✀ᏊⓎⱆ࡜ᡂ㛗࡟୚࠼ࡿᙳ㡪ࢆほᐹࡍࡿࡇ࡜࡜ࡋࡓࠋ
ࡋ࠿ࡋ࡞ࡀࡽࠊ௨ୗࡢ⯆࿡࠶ࡿ▱ぢࡀᚓࡽࢀ࡚࠸
ࡿࠋᐇ㦂࡟౑⏝ࡉࢀࡓ᳜≀✀ࡣࠊࢧࣟ࣋ࢶ‵ཎἾⅣ᥇᥀㊧ᆅ࡛ᐃ╔ࡀㄆࡵࡽࢀࡿከᖺ⏕ⲡᮏ 3 ✀࡛࠶ࡿࠋᖐ໬✀࡟࢚ࢰࣀࢠࢩࢠࢩ(Rumex obtusifoliusL.)ࠊᅾ᮶✀࡟࣡ࢱࢫࢤ(Eriophorum vaginatum L.)࡜࣒࣍ࣟ࢖ࢫࢤ(Carex middendorffii Fr. Schmidt)ࢆ㑅ࢇࡔࠋ✀Ꮚࡣ඲࡚ 2019 ᖺ୰࡟ࠊྛ✀ࡢ✀Ꮚᩓᕸᮇ࡟᥇ྲྀࡋࡓࠋ2019 ᖺ⛅࡟ἾⅣ᥇᥀㊧ᆅ࡛᥇ྲྀࡋࡓ
⾲ᒙࡢἾⅣࢆⓎⱆᗋ࡜ࡋ࡚౑⏝ࡋࡓࠋᑠᆺࢺࣞ࢖
࡟ἾⅣࢆᩜࡁࠊࡑࡢୖ࡟ྜィ 20 ⢏࡜࡞ࡿࡼ࠺ୖグ
3 ✀ࡢ✀Ꮚࢆ᧛✀ࡋࡓࠋෆヂࡣࠊ࢚ࢰࣀࢠࢩࢠࢩ
ࡢ༢᧛ฎ⌮ࠊ࢚ࢰࣀࢠࢩࢠࢩ࡜ᅾ᮶✀ࡢΰ᧛ฎ⌮࡛࠶ࡿࠋྛ✀Ꮚΰྜฎ⌮࡟ᑐࡋ࡚ࠊ᪋⫧࡟ࡼࡾᰤ㣴ศ໙㓄ࢆసࡾᅵተᰤ㣴ࡀⓎⱆᡂ㛗࡟୚࠼ࡿᙳ㡪ࢆ ᐃࡋࡓࠋࡼࡗ࡚ࠊᐇ㦂ࡣࠊ(2 × 2)✀Ꮚฎ⌮ × 3
᪋⫧ฎ⌮ × 5 ཯᚟ࡢィ 120 ࢺࣞ࢖࡛⾜ࡗࡓࠋᩓỈࡣࠊ ᐊࡢ⮬ືࢫࣉࣜࣥࢡ࣮࡛ࣛ 1 ᪥ 7 ᅇ⾜ࡗࡓࠋⓎⱆほᐹࡣࠊྍ⬟࡞㝈ࡾẖ᪥⾜ࡗࡓࠋ࢚ࢰࣀࢠࢩ
ࢠࢩࡣࠊᐇ㦂㛤ጞ࠿ࡽ 1 㐌㛫࡛Ⓨⱆࢆ㛤ጞࡋⓎⱆᮇ㛫ࡣ 1 㐌㛫⛬ᗘ࡛࠶ࡗࡓࠋ㧗⃰ᗘ᪋⫧༊࡛Ⓨⱆ࡜ᡂ㛗ࡣⰋዲ࡛࠶ࡾࠊ࢚ࢰࣀࢠࢩࢠࢩࡢⓎⱆᮇ㛫ࡣ 1 㐌㛫⛬ᗘ࡛࠶ࡗࡓࠋ୍᪉ࠊᅾ᮶✀ 2 ✀ࡢⓎⱆࡣᴟࡵ࡚㐜ࡃࠊ࣡ࢱࢫࢤࡢ᭱ึࡢⓎⱆࡀ☜ㄆࡉࢀࡓࡢࡣ᧛✀࠿ࡽ 1 ࣨ᭶ᚋ࡛࠶ࡗࡓࠋࡲࡓࠊᐇ㦂(1)ࡼࡾࡶⓎⱆ⋡ࡣప࠿ࡗࡓࠋࡇࡢࡇ࡜ࡣࠊ࣡ࢱࢫࢤ
ࡣ▷࿨✀Ꮚ࡛࠶ࡿࡇ࡜ࢆ♧၀ࡋ࡚࠸ࡿࠋ୍᪉ࠊ࣍
࣒ࣟ࢖ࢫࢤ✀ᏊࡣࠊࡲࡗࡓࡃⓎⱆࡋ࡞࠿ࡗࡓࠋ㢧ᚤ㙾ほᐹ࠿ࡽࡣࠊ࣒࣍ࣟ࢖ࢫࢤ✀Ꮚࡢ᩿㠃ࡣ೺඲࡛࠶ࡾࠊ✀Ꮚࡀᮍ⇍࠶ࡿ࠸ࡣṚஸࡋ࡚࠸ࡿࡇ࡜ࡀ
Ⓨⱆࡋ࡞࠸せᅉ࡜ࡣ⪃࠼࡙ࡽࡃࠊ✀Ꮚ࡬ࡢప ฎ⌮ᮇ㛫ࡢຠᯝࢆࠊูಶ࡛ᐇ㦂୰࡛࠶ࡿࠋ⌧ᅾࠊᐇ⏕ࢆสࡾྲྀࡾᆅୖ㒊࠾ࡼࡧᆅୗ㒊ࡢࣂ࢖࣐࢜ࢫ
ᐃࢆ⾜࠸ࠊᡂ㛗࣭㈨※ศ㓄࡟ᑐࡍࡿ᪋⫧ࡢᙳ㡪ࢆᐃࡍࡿணᐃ࡛࠶ࡿࠋ
ㄽᩥ
Nagasato C, Kawamoto H, Tomioka T, Tsuyuzaki S,
Kosugi C, Kato T & Motomura T. (2020) Quantificationof the laminarialian zoospores in seawater by real-time
PCR. Phycologcial Research 68: 57-62
Otaki M & Tsuyuzaki S (2019) Succession oflitter-decomposing microbial organisms in deciduous
birch and oak forests, northern Japan. Acta Oecologica
101, Article 103485
Tsuyuzaki S. (2019) Vegetation changes from 1984 to2008 on Mount Usu, northern Japan, after the
1977-1978 eruptions. Ecological Research 34: 813-820
Ꮫ఍Ⓨ⾲㟢ᓮྐᮁ࣭ᱵᮧᫀᏹ࣭㈩㞵ⴌ. (2020) ࢧࣟ࣋ࢶἾⅣ
᥇᥀㊧ᆅ࡟⛣᳜ࡉࢀࡓ࣑ࢬࢦࢣ࣐ࢵࢺࡢ 2 ᖺ㛫ࡢᐃ╔≧ἣ. ➨66ᅇ᪥ᮏ⏕ែᏛ఍(ྡྂᒇ, ࣏ࢫࢱ࣮)Végh L, Tsuyuzaki S. (2020) Comparing biodiversity
indicators from field and remote sensing observations−8−

on Mount Usu. ➨ 66 ᅇ᪥ᮏ⏕ែᏛ఍(ྡྂᒇ, ࣏ࢫࢱ࣮) ⎔ቃ㐺ᛂ⛉Ꮫศ㔝⤫ྜ⎔ቃ⛉Ꮫ㒊㛛Ἀ㔝 㱟ᩥ㸦ᾏỈ฼⏝㸧ㄽᩥⓎ⾲
Kamada, T., Phan, C., Okino, T. and Vairappan, C. S.
(2019) Cytotoxicity and antibacterial potential of
halogenated chamigrenes from Malaysian red alga,
Laurencia majuscule, Planta Medica International
Open, 6, e36-e40.
Umezawa, T., Prakoso, N. I., Kannaka, M., Nogata, Y.,
Yoshimura, E., Okino, T., and Matsuda, F. (2019)
Synthesis and structure—activity relationship ofOmaezallene derivatives, Chemistry and Biodiversity,
16, e1800451.
⎔ቃ⏕≀⛉Ꮫ㒊㛛 㝣⏕⏕ែᏛศ
ศ㔝ᕤ⸨ ᓅ
◊✲ᚑ஦⪅: ኱ᔱᕼ⨾฼⏝≧ἣ࣭◊✲ᡂᯝ㢧ⰼ᳜≀ࡢ⣙ 8 ๭ࡣ㏦⢊ࢆື≀࡟㢗ࡗ࡚࠾ࡾࠊ
㏦⢊ື≀ࢆຠ⋡ⓗ࡟ㄏᘬࡍࡿࡓࡵ࡟ⰼࡢⰍ࣭ᙧ࣭
㤶ࡾ࡞࡝ࡢಙྕࢆ౑ࡗ࡚࠸ࡿࠋ᫖ᖺᗘࡢ◊✲࡛ࡣࠊ㏆⦕✀࡛᫨ኪ㛫࡛ࡢ㏦⢊⪅ㄏᘬᙧ㉁(ⰼ⻤୰⢾ᗘ࠾ࡼࡧⰾ㤶㔞)ࡢኚ໬ࡀሗ࿌ࡉࢀ࡚࠸ࡿ࣓࣐ࢶࣚ
࢖ࢢࢧ( Oenothera biennis )ࢆᑐ㇟࡟ࠊ㏦⢊⪅ᒙࡢኚ໬࡜⦾Ṫᡂຌᗘࡢ᫨ኪ㛫࡛ࡢ㐪࠸ࢆ᫂ࡽ࠿࡟ࡍࡿ
ࡇ࡜ࢆ┠ⓗ࡜ࡋ࡚◊✲ࢆ⾜࠸ࠊ࣓࣐ࢶࣚ࢖ࢢࢧࡣ
✀Ꮚᙧᡂࡢከࡃࢆ⮬Ṫ࡛ࡲ࠿࡞࠺ࡇ࡜ࡀ࡛ࡁࡿࡇ
࡜ࡀ♧ࡉࢀࡓࠋ௒ᖺᗘࡢ◊✲࡛ࡣࠊ࣓࣐ࢶࣚ࢖ࢢ
ࢧࡀ᫂἞ᮇ࡟⛣ධࡋ࡚ࡁࡓእ᮶✀࡛᪥ᮏ඲ᅜ࡟ᗈ
⠊ᅖ࡟ศᕸࡋ࡚࠸ࡿࡇ࡜ࠊ࠾ࡼࡧᆅ⌮ⓗ࡟ᗈ⠊ᅖ࡟ศᕸࡍࡿ᳜≀࡟࠾࠸࡚ࡣ⦾Ṫᡓ␎ࡸᙧែ≉ᚩ࡟ሙᡤ㛫࡛ኚ␗ࡀ⏕ࡌࡿࡇ࡜ࡀከ࠸ࡇ࡜࠿ࡽࠊ౵␎
ᚋࡢ⦾Ṫᡓ␎ࡸᙧែ≉ᚩࡀ⦋ᗘศᕸ࡟ἢࡗ࡚࡝ࡢ
ࡼ࠺࡟ኚ໬ࡍࡿ࠿ࢆ᫂ࡽ࠿࡟ࡍࡿࡇ࡜ࢆ┠ⓗ࡜ࡋ࡚ࠊ㔝እㄪᰝࢆ⾜ࡗࡓࠋ࡞࠾ࠊࡇࡢ✀ࡣኤ᪉࠿ࡽ
㛤ⰼࡍࡿ୍᪥ⰼࢆኟ࠿ࡽ⛅࡟࠿ࡅ࡚ࡘࡅࡿࡓࡵࠊ
ⰼࡢ㛤ⰼ᫬㛫ࡸ㛤ⰼࣇ࢙ࣀࣟࢪ࣮ࡢ㛗ࡉࡶ㔜せ࡞⦾Ṫᡓ␎࡟࡞ࡿ࡜⪃࠼ࡽࢀࡿࠋࡇࢀࡽࡢ⦾Ṫᡓ␎ࡢ≉ᚩࡢẚ㍑ᑐ㇟⩌࡜ࡋ࡚ࢤࣀ࣒ࢲ࢖ࢼ࣑ࢡࢫࢭ
ࣥࢱ࣮᪋タෆࡢᐇ㦂ᅡሙ࡟࠾࠸࡚⛣᳜ಶయ⩌(௨ୗᮐᖠࠊn=62)ࢆసᡂࡋẚ㍑᳨ドࢆ⾜ࡗࡓࠋ࡞࠾ࠊ
⛣᳜ಶయ⩌ࡣ 2019 ᖺ 6 ᭶࡟໭ᾏ㐨▼⊁ᕷࠕࡣࡲ࡞ࡍࡢୣබᅬࠖ࠿ࡽ᥇ྲྀࡋࡓಶయࢆ⏝࠸࡚సᡂࡋ
ࡓࠋ㔝እㄪᰝ࡟࠾࠸࡚ࡣࠊࡣࡲ࡞ࡍࡢୣබᅬ(n=44)ࠊ
Ⲉᇛ┴ࡦࡓࡕ࡞࠿ᕷᅜႠࡦࡓࡕᾏ὾බᅬ(n=40)ࠊ㫽ྲྀ┴⡿Ꮚᕷ⡿ᏊỈ㫽බᅬ(n=24)ࡢ 3 ᆅⅬ(ࡑࢀࡒࢀ௨ୗ▼⊁ࠊ᪥❧ࠊ⡿Ꮚ)࡛⾜ࡗࡓࠋձ ⰼ࠾ࡼࡧ᳜≀ಶయࡢᙧែⓗ≉ᚩࡢẚ㍑ ྛㄪᰝᆅⅬ࡟࠾࠸࡚ࠊⰼࡢ኱ࡁࡉ(ⰼࡢ㛗ᚄ࣭▷ᚄ࣭ⰼ⟄㛗)࡜ಶయࢧ࢖ࢬ(ᆅ㝿┤ᚄ࣭㧗ࡉ)ࢆ ᐃࡋ࡚ẚ㍑ࢆ࠾ࡇ࡞ࡗࡓࠋⰼࢧ࢖ࢬ࡟࠾࠸࡚ࡣࠊ▼⊁࡜ᮐᖠࡀ࡯࠿ࡢ 2 ᆅⅬࡼࡾࡶ᭷ព࡟኱ࡁ࠸ࡇ
࡜ࡀ᫂ࡽ࠿࡟࡞ࡗࡓࠋ୍᪉࡛ಶయࢧ࢖ࢬࡣࠊ▼⊁࡜᪥❧࡛ᑠࡉࡃ࡞ࡗࡓࠋղ 㛤ⰼࣇ࢙ࣀࣟࢪ࣮࡜㛤ⰼ᫬㛫ࡢ ᐃ㔝እಶయ⩌ 3 ᆅⅬ࡜ᮐᖠಶయ⩌࡟࠾࠸࡚ࠊྛಶయࡀ࠸
ࡘ᭱ึࡢⰼࢆဏ࠿ࡏࡿ࠿ࢆグ㘓ࡋࡓࠋࡲࡓࠊ㛤ⰼ᫬㛫࡟ࡘ࠸࡚ࡣᮐᖠ࡟࠾࠸࡚ᐃⅬ࣓࢝ࣛࢆタ⨨ࡋࠊ7 ᭶ 1 ᪥࠿ࡽ 10 ᭶ 28 ᪥ࡲ࡛ࡢྛ㐌࡛ⰼࡢ㛤ⰼ᫬㛫ࢆ ᐃࡋࡓࠋ㛤ⰼࣇ࢙ࣀࣟࢪ࣮
ࡣ㧗⦋ᗘᆅᇦ࡛᪩ࡲࡿഴྥࡀ࠶ࡾࠊ୍᪥ࡢ୰࡛
ࡢ㛤ⰼ㛤ጞ᫬㛫ࡣ㧗⦋ᗘᆅᇦ࡛᪩࠸ࡇ࡜ࡀ᫂
ࡽ࠿࡟࡞ࡗࡓࠋ㛤ⰼ᫬㛫ࢆㄝ᫂ኚᩘࠊ㐌ࢆᛂ⟅ኚᩘࠊࣛࣥࢲ࣒ຠᯝࢆಶయ ID ࡜ࡋ࡚⥺ᙧᅇᖐࢆ⾜࠸ࠊࡇࡢᅇᖐ⥺࡜ྛㄪᰝᆅⅬ࡜ࡢࡎࢀࢆ
ᐃࡋࡓࠋࡇࡢ⤖ᯝࠊ▼⊁࡜ᮐᖠࡢಶయ⩌ࡣ㛤ⰼ㛤ጞ᫬㛫ࡀ኱ࡁࡃኚࢃࡽ࡞࠿ࡗࡓࡀࠊ᪥❧࣭⡿Ꮚ୧ಶయ⩌ࡣᮐᖠࡼࡾࡶ㐜ࡃ㛤ⰼࡍࡿഴྥ࡟
࠶ࡗࡓࠋ௨ୖࡢ⤖ᯝ࡜Ẽ㇟᮲௳ࡢゎᯒ࠿ࡽࠊᙧែⓗ≉ᚩࡢಶయ⩌㛫ኚ␗ࡣ㢼ຊ࡞࡝ࡢẼ㇟᮲௳࡟ᛂࡌ࡚ኚ
໬ࡋ࡚࠸ࡿ࡜⪃࠼ࡽ࠼ࡓࠋࡲࡓࠊ㧗⦋ᗘᆅᇦ࡛ࡣ
⏕⫱ࢩ࣮ࢬࣥࡀ▷࠸ࡓࡵࠊ㛤ⰼࣇ࢙ࣀࣟࢪ࣮ࡀ᪩
ࡲࡾࠊ࠿ࡘ㛤ⰼᮇ㛫ࡀ▷ࡃ࡞ࡿ࡜⪃࠼ࡽࢀࡓࠋ⏕⫱ዲ㐺ᮇ㛫ࡀ㝈ࡽࢀࡿࡓࡵࠊ⦾Ṫ࡬ࡢ㈨※ᢞ㈨㔞
ࢆቑ኱ࡉࡏ࡚ࡶ⥲✀Ꮚ⏕⏘㔞ࡣ㢌ᡴࡕ࡟࡞ࡿ࡜᥎
ࡉࢀࡓࠋ୍᪉࡛ࠊኪ㛫ࡢ㏦⢊⪅ࡔࡅ࡛࡞ࡃኤᬽ
ࢀ᫬ࡢ㏦⢊⪅ࡶ฼⏝ࡍࡿࡓࡵ࡟ࠊⰼࡢࢹ࢕ࢫࣉࣞ
࢖ࢧ࢖ࢬࡢቑ኱ࡸࠊ㛤ⰼ᫬㛫ࡢኚ᭦ࡀ㐍໬ࡋࡓࡢ࡛ࡣ࡞࠸࠿࡜♧၀ࡉࢀࡓࠋ᫖ᖺ࠿ࡽࡢ⥅⥆◊✲࡜ࡋ࡚ࠊⰼࡢ㤶ࡾࡢᆅᇦ㛫ẚ㍑ࡶ⾜ࡗ࡚࠸ࡿࡀࠊࡑ
ࢀ࡟㛵ࡋ࡚ࡣ⌧ᅾゎᯒ୰࡛࠶ࡿࠋ
Ꮫ఍Ⓨ⾲኱ᔱᕼ⨾㸪ᕤ⸨ᓅ:࣓࣐ࢶࣚ࢖ࢢࢧࡢ㛤ⰼ≉ᛶ࡜ࣃࣇ࢛࣮࣐ࣥࢫࡢᆅ⌮ⓗኚ␗.᪥ᮏ⏕ែᏛ఍➨ 67 ᅇ኱఍㸪2020 ᖺ 3 ᭶ 8 ᪥㸪ྡᇛ኱Ꮫ㸦ྡྂᒇᕷ㸧኱Ꮫ㝔⌮Ꮫ◊✲㝔≀⌮Ꮫ㒊㛛 㔞Ꮚ≀⌮Ꮫศ㔝ᯇỌ ᝅ᫂㸦⣧Ỉ฼⏝㸧ㄽᩥⓎ⾲
"Co-appearance of superconductivity and ferromagnetismin a Ca2RuO4 nanofilm crystal",
H. Nobukane, K. Yanagihara, Y. Kunisada, Y. Ogasawara,
K. Isono, K. Nomura, K. Tanahashi, T. Nomura, T.

−9−

Akiyama and S. Tanda, Scientific Reports, 10 3462 (2020)"Coexistence of the Kondo effect and spin glass
physics in Fe-doped NbS2",
H. Nobukane, Y. Tabata, T. Kurosawa, D. Sakabe and S.
Tanda, Journal of Physics: Condensed Matter, 32
165803 (2020)
Ꮫ఍Ⓨ⾲"Emergence of high-temperature superconductivity ina Ca2RuO4 nanocrystals",
H. Nobukane, K. Yanagihara, Y. Kunisada, Y. Ogasawara,
K. Isono, K. Nomura, K. Tanahashi, T. Nomura, T.
Akiyama, and S. Tanda, The APS March Meeting 2020
March 2-6 2020, Denver, Colorado

and charge order in the organic superconductorE”-(BEDT-TTF)4[(H3O)Ga(C2O4)3]‫ڄ‬C6H5NO2.
Physical Review B 100, 060505(R).
Kobayashi, T., Suzuta, A., Tsuji, K., Ihara, Y., andKawamoto, A. (2019) Inhomogeneous electronic stateof organic conductor N-(BEDT-TTF)2Cu[N(CN)2]I
studied by 13C NMR spectroscopy. Physical Review B
100, 195115.
Ohnuma, A., and Kawamoto, A. (2019) 13C-NMR
study of charge fluctuation in D-(BEDT-TTF)MX salts(M = alkali metal; X = S, Se). Physical Review B 100:
245107.

π-d 㟁Ꮚ⣔ λ-(STF)2FeCl4 ࡢ㟁Ꮚࢫࣆࣥඹ㬆኱ᓥຬ࿃, Taehoon LeeA, ༡⯓Ꮥு, ᩪ⸨ὒᖹ, Ἑᮏ ඘ ྖ , ᯇ Ọ ᝅ ᫂ , ຍ ⸨ ♩ ୕ . ᪥ ᮏ ≀ ⌮ Ꮫ ఍2019 ᖺ⛅Ꮨ኱఍. 2019 ᖺ 9 ᭶ 10 ᪥㹼13 ᪥

Saito, Y., Rösslhuber, R., Löhle, A., Sanz Alonso, M.,
Wenzel, M., Kawamoto, A., Pustogow, A., and Dressel,
M. (2000) Bandwidth tuning from insulating Mott
quantum spin liquid to Fermi liquid via chemical
substitution in N-[(BEDT-TTF)1-x(BEDT-STF)x]2Cu2(CN)3.
Physical Review B accepted.

π-d ⣔᭷ᶵᑟయ λ’-(BEDT-STF)2FeBr4 ࡢ☢ᛶ࡟࠾ࡅࡿᚤどⓗᥥീ
༡⯓Ꮥு, ኱ᓥຬ࿃, ࿴⏣኱㜿, ᯇỌᝅ᫂, 㔝ᮧ୍ᡂ, ຍ⸨♩୕. ᪥ᮏ≀⌮Ꮫ఍ 2019 ᖺ⛅Ꮨ኱఍.
2019 ᖺ 9 ᭶ 10 ᪥㹼13 ᪥

Kobayashi, T., Ishikawa, T., Ohnuma, A., Sawada, M.,
Matsunaga, N., Uehara, H., and Kawamoto, A. (2020)
Spin-density wave in the vicinity of superconducting
state in O-(BETS)2GaBrxCl4-x probed by 13C NMR
spectroscopy. Physical Review Research accepted.

ᨃ୍ḟඖ᭷ᶵᑟయ(DMET-TTF)2AuBr2 ࡢ㟁Ꮚ≀ᛶబࠎᮌ⩏᫂, ᅵᒇᬛᩗ, ⃝⏣㈼ᚿ, ᯇỌᝅ᫂, Ἑᮏ඘ྖ, 㔝ᮧ୍ᡂ. ᪥ᮏ≀⌮Ꮫ఍ 2019 ᖺ⛅Ꮨ኱఍.
2019 ᖺ 9 ᭶ 10 ᪥㹼13 ᪥

Ꮫ఍Ⓨ⾲
ᅜ㝿఍㆟
S. Fukuoka, T. Minamidate, N. Matsunaga, K. Nomura, Y.
Ihara, and A. Kawamoto: Magnetic and Thermodynamic
Properties of Molecular S-d system O-(BEDT-STF)2FeCl4㸬
International Symposium on Crystalline Organic Metals,
Superconductors and Magnets (ISCOM2019),
September 22-27, 2019, Tomar, Portugal.

ᒙ≧ࣝࢸࢽ࣒࢘㓟໬≀ࢼࣀࢫࢣ࣮ࣝ⤖ᬗࡢ㍺㏦⌧
㇟♒㔝⩧, ᘏවၨ⣧, ᰗཎ⯆ୡ, ᑠ➟ཎඃோ, ᅧ㈆㞝
἞, Ჴᶫ្ኴ, ⬟ᮧ㈗ᏹ, ⛅ᒣ཭ᏹ, 㔝ᮧ୍ᡂ, ୹⏣⪽. ᪥ᮏ≀⌮Ꮫ఍ 2019 ᖺ⛅Ꮨ኱఍. 2019 ᖺ 9 ᭶
10 ᪥㹼13 ᪥ᨃ୍ḟඖ᭷ᶵᑟయ(DMET-TTF)2AuBr2 ࡢ㟁Ꮚ≀ᛶ(2)㣤⏣⍱ᖹ, బࠎᮌ⩏᫂, ᅵᒇᬛᩗ, ⃝⏣㈼ᚿ, ᯇỌᝅ᫂, Ἑᮏ඘ྖ, 㔝ᮧ୍ᡂ. ᪥ᮏ≀⌮Ꮫ఍➨ 75 ᅇᖺḟ኱఍. 2020 ᖺ 3 ᭶ 16 ᪥㹼19 ᪥
Fe1+xTe ࡢㄏ㟁⋡ ᐃᶓ஭༓⇊, ᐑᔘ୍ㄔ, 㔠஭ᜤభ, ᕷᮧ᫭୍, ୹⏣⪽,ᯇỌᝅ᫂, 㯮⃝ᚭ. ᪥ᮏ≀⌮Ꮫ఍➨ 75 ᅇᖺḟ኱఍.
2020 ᖺ 3 ᭶ 16 ᪥㹼19 ᪥≀⌮Ꮫ㒊㛛 㟁Ꮚ≀ᛶ≀⌮Ꮫศ㔝Ἑᮏ ඘ྖ㸦⣧Ỉ฼⏝㸧ㄽᩥIhara, Y., Moribe, K., Fukuoka, S., and Kawamoto, A.
(2019) Microscopic coexistence of superconductivity

A. Ohnuma, and A. Kawamoto: The Horizontal Stripe
Modulation of D-Type Salts Examined by 13C-NMR Studyon the Metallic Salt of D-(BEDT-TTF)2TlHg(SeCN)4.
International Symposium on Crystalline Organic
Metals, Superconductors and Magnets (ISCOM2019),
September 22-27, 2019, Tomar, Portugal.
T. Kobayashi, K. Tsuji, T. Ishikawa, A. Ohnuma, and A.
Kawamoto: Evidence of the Spin-Density-Wave
Fluctuation in O-(BETS)2GaCl4 Probed by 13C and
69/71
Ga NMR Spectroscopy.
International Symposium on Crystalline Organic
Metals, Superconductors and Magnets (ISCOM2019),
September 22-27, 2019, Tomar, Portugal.
M. Sawada, Y. Saito, S. Fukuoka, and A. Kawamoto:
13
C NMR Study of the Electronic Properties of
O-(ET)2GaCl4 Under Pressure.
International Symposium on Crystalline Organic
Metals, Superconductors and Magnets (ISCOM2019),
September 22-27, 2019, Tomar, Portugal.
T. Ishikawa, A. Kawamoto, and T. Koabyashi:− 10 −

Spin-Density-Wave Near Superconductivity in a
System of O-(BETS)2GaBrxCl4-x Probed by 13C-NMR.
International Symposium on Crystalline Organic
Metals, Superconductors and Magnets (ISCOM2019),
September 22-27, 2019, Tomar, Portugal.
Y. Ihara, K. Arashima, M. Hirata, T. Sasaki, and H.
Yoshida: 35Cl NMR study for anisotropic low-energy
magnetic excitations in perfect kagome antiferromagnet
Ca-kepellasite.
International Conference on Strongly CorrelatedElectron Systems (SCES2019), September 23-28, 2019,
Okayama, Japan.
K. Arashima, Y. Ihara, K. Matsui, K. Kindo, Y.
Kohama, M. Hirata, T. Sasaki, Y. Ishii, and H. Yoshida:
7
Li NMR study for the breathing Kagome
antiferromagnet Li2Cr3SbO8.
International Conference on Strongly CorrelatedElectron Systems (SCES2019), September 23-28, 2019,
Okayama, Japan.
ᅜෆᏛ఍⚟ ᒸ ⬶ ᖹ  ᫓ ᒣ ࿴ ᕼ  ஭ ཎ ៞ ᙪ  Ἑ ᮏ ඘ ྖ 㸸O %('767) )H[*D[&O ΰᬗ⣔ࡢ☢Ẽ≧ែ㸬᪥ᮏ≀⌮Ꮫ఍  ᖺ⛅Ꮨ኱఍㸪 ᖺ  ᭶  ᪥̿ ᪥㸪ᒱ㜧኱Ꮫ㸦ᒱ㜧ᕷ㸧㸬
୕ᯞ኱㍜⚟ᒸ⬶ᖹ஭ཎ៞ᙪἙᮏ඘ྖ㧗ᶫᖾ⿱➉ஂ⨾ె⏣୰ᜨ㔛ཎ⏣₶✄㎶ಖ㸸᭷ᶵศᏊࢆᤄධࡋࡓ 77)&$ 㢮⦕యࡢ㟁Ꮚ≧ែ㸬᪥ᮏ≀⌮Ꮫ఍  ᖺ⛅Ꮨ኱఍㸪 ᖺ  ᭶  ᪥̿ ᪥㸪ᒱ㜧኱Ꮫ㸦ᒱ㜧ᕷ㸧㸬஭ཎ៞ᙪⲨᓥὯᶞ຾ྜྷྖᮌᮧ೺ኴᮌᮧ
๛㸸ᐃᖖ☢ሙ 105 ᐃ࡟ࡼࡿṇᅄゅྎሪᆺ཯ᙉ☢
ᛶయ 3E 7L2 &X 32  ࡢప☢ሙ┦ࡢ☢Ẽᵓ㐀ほ 㸬᪥ᮏ≀⌮Ꮫ఍  ᖺ⛅Ꮨ኱఍㸪 ᖺ  ᭶  ᪥̿ ᪥㸪ᒱ㜧኱Ꮫ㸦ᒱ㜧ᕷ㸧㸬㒊㛛 ᙧែᶵ⬟Ꮫศศ㔝⏕≀⛉Ꮫ㒊ᒣཱྀ ῟஧1) ᳜≀⣽⬊࡟࠾ࡅࡿ⢾ࢩࢢࢼࣝఏ㐩ࢆไᚚࡍࡿ᪂つᅉᏊ ATL8 ࡢ◊✲ࠋࢩࣟ࢖ࢾࢼࢬࢼࢆᮦᩱ࡟㸪
ATL8 ࡀ⭷ᒁᅾᛶࡢࣘࣅ࢟ࢳ࣮ࣥࣜ࢞ࢮ࡜ࡋ࡚ᶵ
⬟ࡋ㸪⢾㣚㣹᮲௳࡟࠾ࡅࡿࢩࢢࢼࣝఏ㐩࡟㛵୚ࡍࡿࡇ࡜ࢆ♧ࡋࡓࠋࡉࡽ࡟㸪ATL8 ࡢࣘࣅ࢟ࢳࣥ໬ᶆ
ⓗೃ⿵ᅉᏊࢆ᥈⣴ࡋ㸪ATL8 ࡀࢹࣥࣉࣥྜᡂ㓝⣲࡜┦஫స⏝ࡍࡿࡇ࡜ࢆぢฟࡋࡓࠋ[Luo et al, Plant
Biotechnology 2019]2) ࢩࣟ࢖ࢾࢼࢬࢼࡢ࣏ࣜ㸿ศゎ㓝⣲ AtCCR4 ࡀ
AtNOT1 ࢆ㊊ሙ࡜ࡋࡓᕧ኱」ྜయࢆᙧᡂࡋ࡚࠸ࡿ
ࡇ࡜ࢆ♧ࡋࡓࠋ」ྜయ࡟ࡣᶆⓗ㑇ఏᏊࡢㄆ㆑࡟㛵ࢃࡿ࡜⪃࠼ࡽࢀࡿ RNA ⤖ྜࢱࣥࣃࢡ㉁ࡶྵࡲࢀ

࡚࠸ࡓࠋ [Arae et al, Plant and Cell Physiology 2019]ࠋ
3㸧
AtNOT1 ࡢኚ␗ᰴࡀ㞝ᛶ㓄അయ⮴Ṛ࡜࡞ࡿࡢࡣ㸪ⰼ⢊ࡢᙧᡂ㜼ᐖࡀཎᅉ࡛࠶ࡿࡇ࡜ࢆ᫂ࡽ࠿࡟ࡋࡓࠋ
࣊ࢸࣟ᥋ྜయࢆ⏝࠸ࡓゎᯒ࠿ࡽ㸪ⰼ⢊ᙧᡂ᫬ࡢ㈇ࡢⓎ⌧ไᚚ࡟㛵ࢃࡗ࡚࠸ࡿྍ⬟ᛶࢆ♧ࡋࡓࠋ
[Motomura et al, Plant and Cell Physiology 2020]4)ኴ㝧ගࡢ෇೫ගᛶࡀ࡝ࡢࡼ࠺࡟᳜≀ࡢᡂ㛗ࢆไᚚࡍࡿ࠿࡟ࡘ࠸࡚ࡢ◊✲ࠋࢩࣟ࢖ࢾࢼࢬࢼࡸࣞࢱ
ࢫࢆ⏝࠸ࡓ◊✲ࡼࡾ㸪Ⓨⱆࡸୗ⬇㍈ࡢᡂ㛗࡟࠾࠸࡚ྑ೫ගࡀຠᯝⓗ࡟స⏝ࡍࡿࡇ࡜ࢆド᫂ࡋࡓࠋኚ
␗యࢆ⏝࠸ࡓᙧ㉁ࡢゎᯒࡸࣇ࢕ࢺࢡ࣮࣒ࣟศᏊࡢ
≀⌮໬Ꮫⓗ≉ᛶࡼࡾ㸪ࡇࡢࡼ࠺࡞ྑ೫ගࡢస⏝ࡣࣇ࢕ࢺࢡ࣮࣒ࣟࢆ௓ࡋ࡚స⏝ࡋ࡚࠸ࡿࡇ࡜ࢆ᫂ࡽ
࠿࡟ࡋࡓࠋ[Lkhamkhuu et al, Plant Biotechnology
2020]5) ᳜≀ࡀ⢾/❅⣲㸦C/N㸧ᰤ㣴ࣂࣛࣥࢫ࡟ᛂ⟅ࡍࡿศᏊᶵᵓ࡟ࡘ࠸࡚㸪⣽⬊ෆࣜࣥ㓟໬ࢩࢢࢼࣝఏ㐩ࢿࢵࢺ࣮࣡ࢡ࡟ࡘ࠸࡚⥙⨶ⓗ࡟ゎᯒࡋࡓ◊✲ࠋࢩࣟ࢖ࢾࢼࢬࢼࢆᮦᩱ࡟㸪ࣜࣥ㓟໬ࣉࣟࢸ࣮࣒࢜ゎᯒࢆᐇ᪋ࡋ㸪ࡇࢀࡲ࡛࡟࡞࠸኱つᶍ࡞ C/N ࢩࢢࢼࣝఏ㐩ࢿࢵࢺ࣮࣡ࢡࡢ᝟ሗࡀᚓࡽࢀࡓࠋࡲࡓ㸪ᰤ㣴ࢩࢢࢼࣝ࡜⣽⬊Ṛไᚚ࡟㛵ࢃࡿ᪂つཷᐜయᆺ࢟
ࢼ࣮ࢮ LMK1 ࢆ༢㞳ࡋࡓࠋ[Li et al, Frontiers in
Plant Science 2020]6) ࣔࢹࣝస≀✀࡛࠶ࡿࢺ࣐ࢺࡢᯝᐇࢆ⏝࠸ࡓࣉࣟࢸ࣮࣒࢜ゎᯒᡭἲ࡟㛵ࡋ࡚ᇳ➹ࡋࡓࠋᯝᐇ࡟࠾
ࡅࡿ௦ㅰ㓝⣲ࡢάᛶไᚚ࡟㛵ࢃࡿ 14-3-3 ࢱࣥࣃࢡ㉁ࡢᶆⓗᅉᏊ࡟ࡘ࠸࡚㸪ᙜ◊✲ᐊ࡛ᐇ᪋ࡋࡓࣁ࢖
ࢫ࣮ࣝࣉࢵࢺ࠿ࡘ⥙⨶ⓗ࡞ࣉࣟࢸ࣮࣒࢜ゎᯒᡭἲ࡟ࡘ࠸࡚ゎㄝࡋࡓࠋ[Luo et al, “Plant Proteomics:
Methods and Protocol, Third Edition” 2019]7) ࠕ⎔ቃࢫࢺࣞࢫ࡟ᙉࡃࡍࡿࣂ࢖࢜ࢫࢸ࢕࣑ࣗࣛ
ࣥࢺࠖࡢ≉㞟࡜ࡋ࡚㸪ࠕ᳜≀࡟ᑐࡍࡿங㓟⳦ᇵ㣴ᾮࡢᶵ⬟ᛶࠖ࡜㢟ࡋ࡚㸪ங㓟⳦ᇵ㣴ᾮࡼࡾ༢㞳ࡋࡓ᳜≀ᡂ㛗ಁ㐍≀㉁ L-ࣇ࢙ࢽࣝங㓟ࡢᶵ⬟࡟ࡘ࠸࡚ࡢᴫせࢆグࡋࡓࠋ [┾ᮌ㸤ᒣཱྀ, in ᭱᪂㎰ᴗᢏ⾡ࠗᅵተ᪋⫧࠘ 2020]㸺ཎⴭㄽᩥ㸼
Luo, Y., Aoyama, S., Fukao, Y., Chiba, Y., Sato, T.
and Yamaguchi, J. (2019) Involvement of themembrane-localized ubiquitin ligase ATL8 in thesugar starvation response in Arabidopsis. Plant
Biotechnology,36:107-112[10.5511/plantbiotechnology.19.0328a]
Arae, T., Morita, K., Imahori, R., Suzuki, Y., Yasuda, S.,
Sato, T., Yamaguchi, J. and Chiba, C. (2019)
Identification of Arabidopsis CCR4-NOT complexes
with Pumilio RNA binding proteins, APUM5 andAPUM2. Plant and Cell Physiology, 60:
2015-2025 [10.1093/pcp/pcz089]
Motomura, K., Arae, T., Uramoto, A.H., Suzuki, Y.,
Takeuchi, H., Suzuki, T., Ichihashi, Y., Shibata,− 11 −

A., Shirasu, K., Takeda, A., Higashiyama, T.
and Chiba Y. (2020) AtNOT1 is a novel
regulator of gene expression during pollen
development. Plant and Cell Physiology, in press
Lkhamkhuu, E., Zikihara, K., Katsura, H., Tokutomi,
S., Hosokawa, T., Usami, Y., Ichihashi, M.,
Yamaguchi, J. and Monde, K. (2020) Effect ofCircularly Polarized Light on Germination,
Hypocotyl Elongation and Biomass Production of
Arabidopsis and Lettuce; Involvement of
Phytochrome B. Plant Biotechnology, 37: 1-11
[10.5511/plantbiotechnology.19.1219a]
Li, X., Sanagi, M., Yu, L., Nomura, Y., Stolze, S.C.,
Yasuda, S., Saijo, Y., Schulze, W.X., Feil, R.,
Lunn, J.E., Stitt, M., Nakagami, H., Sato, T. andYamaguchi, J. (2020) Protein phosphorylation
dynamics under carbon/nitrogen-nutrient stressand identification of a cell death-related
receptor-like kinase in Arabidopsis. Frontiers in
Plant Science, accepted㸺⥲ㄝ㸼Luo, Y., Lu, Y., Yamaguchi, J. and Sato, T. (2019)
Chapter 21, Proteome analysis of 14-3-3 targets
in tomato fruit tissues. In “Plant Proteomics:
Methods and Protocol, Third Edition” (edited by
J.V. Jorrín Novo, L. Valledor, and M.A. Castillejo)
Methods in Molecular Biology, Springer Protocol,
Humana Press, in press┾ᮌ♸Ꮚ㸪ᒣཱྀ῟஧ (2020) ᳜≀࡟ᑐࡍࡿங㓟⳦ᇵ㣴ᾮࡢᶵ⬟ᛶ㸪᭱᪂㎰ᴗᢏ⾡ࠗᅵተ᪋⫧࠘➨ 12 ᕳ㸪<⎔ቃࢫࢺࣞࢫ࡟ᙉࡃࡍࡿࣂ࢖࢜ࢫ
ࢸ࢕࣑ࣗࣛࣥࢺ> pp. 13-15㸪㎰ᒣ⁺ᮧᩥ໬༠఍
㒊㛛 ⾜ື⚄⤒⏕≀Ꮫศศ㔝⏕≀⛉Ꮫ㒊ᑠᕝ ᏹே
௧࿴ඖᖺᗘ◊✲ᡂᯝᐇ㦂⏕≀ඹྠ฼⏝㒊㛛࡛㣫⫱ࡋࡓࣇࢱ࣍ࢩࢥ࢜ࣟ
ࢠ㸦Gryllus bimaculatus㸧ࢆᮦᩱ࡜ࡋ࡚㺂⚄⤒⏕≀Ꮫⓗᐇ㦂ࢆ⾜ࡗࡓࠋ ࢥ࢜ࣟࢠࡣ㺂⭡㒊ᮎ➃ࡢᑿⴥ࡜࿧ࡤࢀࡿᶵᲔឤぬჾᐁ࡛✵Ẽὶ᣺ືࢆཷᐜࡋ㺂▷࠸Ẽὶ่⃭࡟ᑐࡋ࡚⣲᪩ࡃ㐲ࡊ࠿ࡿṌ⾜⾜ືࢆ♧ࡍࠋࡇࡢ⾜ືࡣẼὶࢆᤕ㣗⪅ࡢ᥋㏆࡜ᤊ࠼㺂ᤕ㣗࠿ࡽ㏨ࢀࡼ࠺࡜
ࡍࡿ㏨㑊⾜ື࡛࠶ࡿ࡜⪃࠼ࡽࢀ࡚࠸ࡿࠋࡲࡓ㺂࢜ࢫࢥ࢜ࣟࢠࡢⓎࡍࡿㄏᘬḷ࡟ᑐࡋ࡚࣓ࢫࡣ㡢※࡟㏆௜࠸࡚࠸ࡃ᥋㏆⾜ື㸦㡢※ᐃ఩㸧ࢆ♧ࡍࠋᡃࠎࡣ
ࡇࢀࡲ࡛࡟㺂Ẽὶឤぬ᝟ሗฎ⌮ࡢ⚄⤒ᶵᵓ࡜Ẽὶ
ㄏᑟᛶ㏨㑊⾜ື㺂ཬࡧ㡢※ᐃ఩⾜ື࡟㛵ࡍࡿ⚄⤒⾜ືᏛⓗ◊✲ࢆ⾜ࡗ࡚ࡁࡓࠋᮏᖺᗘࡣ௨ୗࡢ◊✲࡟㛵ࡍࡿᡂᯝࢆᚓࡓࠋ
ࢥ࢜ࣟࢠ⬻ෆ࡟࠾ࡅࡿከឤぬࢽ࣮ࣗࣟࣥࡢᛂ⟅≉ᛶゎᯒࢥ࢜ࣟࢠࡣ⫈ぬ่⃭࡟ᑐࡋࠊཷᐜࡍࡿ㡢ࡢ㧗ࡉ࡟ࡼࡗ࡚␗࡞ࡿ⾜ືࢆ♧ࡍࠋྠ✀࢜ࢫࡢㄏᘬḷࡢࣃࢱ࣮ࣥࡢ㡢่⃭࡟ᑐࡋ࡚ࠊࡑࡢ࿘Ἴᩘࡀㄏᘬḷ࡜ྠࡌ 5 kHz ࡢሙྜ࡟ࡣࠊ㡢※࡟㏆௜࠸࡚࠸ࡃṇࡢ㉮㡢ᛶࢆ♧ࡍࡀࠊᤕ㣗⪅࡛࠶ࡿࢥ࢘ࣔࣜࡢ᥈⣴㡢Ἴ࡟㏆࠸㧗࿘Ἴ㡢࡟࡞ࡿ࡜ࠊ㣕⩧୰࡟่⃭࠿ࡽ
㏨ࡊ࠿ࢁ࠺࡜ࡍࡿ㈇ࡢ㉮㡢ᛶࢆ♧ࡍࠋࡲࡓࠊ▷࠸Ẽὶ่⃭࡟ᑐࡋ࡚ࡣࠊ่⃭ࡢ཯ᑐ᪉ྥ࡟⛣ືࡍࡿ
㏨㑊⾜ືࢆ♧ࡍࠋ࠸ࡎࢀࡶ่⃭࡟ᑐࡋ࡚ᐃ఩ࢆ⾜࠺ࡇ࡜࠿ࡽࠊ⫈ぬ⣔ࡶẼὶឤぬ⣔ࡶ่⃭ࡢ᪉ྥࢆ᳨ฟࡍࡿ⬟ຊࢆᣢࡘࡇ࡜ࡀศ࠿ࡿࠋ㡢่⃭࠾ࡼࡧẼὶ่⃭ࡢ᪉ྥ᝟ሗࢆฎ⌮ࡍࡿ⚄⤒ᅇ㊰ࡣࠊࡑࢀࡒࢀ๓⬚⚄⤒⠇࠾ࡼࡧ᭱⤊⭡㒊⚄⤒⠇ෆ࡟Ꮡᅾࡋࠊ
่⃭࡟ᑐࡋ࡚᪉ྥឤཷᛶࢆᣢࡘୖ⾜ᛶࢽ࣮ࣗࣟࣥ
࡟ࡼࡗ࡚⬻࡬ఏ㐩ࡉࢀ࡚࠸ࡿࠋࡋࡓࡀࡗ࡚ࠊࢥ࢜
ࣟࢠࡢ⬻ෆ࡛⫈ぬ่⃭࡜Ẽὶ่⃭ࡢ᪉ྥ᝟ሗࡀㄞ
ࡳฟࡉࢀ࡚ࠊୖグࡢᐃ఩⾜ືࡀไᚚࡉࢀ࡚࠸ࡿ࡜
⪃࠼ࡽࢀࡿࠋࡇࢀࡲ࡛࡟ࠊࢥ࢜ࣟࢠ⬻ෆ࡟ࡣ」ᩘ
✀ࡢ่⃭࡟ᛂ⟅ࡍࡿከឤぬࢽ࣮ࣗࣟࣥࡀ࠸ࡃࡘ࠿
ྠᐃࡉࢀ࡚࠸ࡿࡀࠊࡑࢀࡽࡢᛂ⟅࡟࠾ࡅࡿ่⃭᪉ྥឤཷᛶࡣ୙࡛᫂࠶ࡿࠋࡑࡇ࡛ᮏ◊✲ࡣࠊࢥ࢜ࣟ
ࢠ⬻ෆ࡟࠾ࡅࡿ␗✀ឤぬࡢ᪉ྥ᝟ሗࡢ⤫ྜ࣓࢝ࢽࢬ࣒ࢆ᫂ࡽ࠿࡟ࡍࡿࡇ࡜ࢆ┠ⓗ࡜ࡋ࡚ࠊ⬻ෆከឤぬࢽ࣮ࣗࣟࣥࡢẼὶ่⃭࡜㡢่⃭࡟ᑐࡍࡿ᪉ྥឤ
ཷᛶࢆゎᯒࡋࡓࠋ⿕そࢱࣥࢢࢫࢸࣥ࣡࢖ࣖ࠿ࡽసᡂࡋࡓࢸࢺ࣮ࣟ
ࢻ㟁ᴟࢆ⬻ෆࡢ␗࡞ࡿ㸳ࡘࡢ㡿ᇦ࡟่ධࡋ㺂 5
kHz ࡲࡓࡣ 15 kHz ࡢࢺ࣮ࣥࣃࣝࢫࢆㄏᘬḷ࡜ྠࡌࣃࢱ࣮࡛ࣥᵓᡂࡋࡓ㡢่⃭࡜㺂ὶ㏿ 0.56 m/s㺂ᣢ⥆᫬㛫 200 ms ࡢẼὶࣃࣇ่⃭࡟ᑐࡍࡿ⚄⤒ᛂ⟅ࢆ⣽⬊እグ㘓ࡋࡓࠋࢫࣃ࢖ࢡࢯ࣮ࢸ࢕ࣥࢢ࡟ࡼࡗ࡚ᢳ
ฟࡋࡓࣘࢽࢵࢺࡈ࡜࡟㺂㸱✀ࡢ่⃭࡟ᑐࡍࡿᛂ⟅ᛶ࡜᪉ྥ㑅ᢥᛶࢆゎᯒࡋࡓ࡜ࡇࢁࠊグ㘓㒊఩࡟ࡼࡗ࡚ከឤぬࣘࢽࢵࢺࡢ๭ྜࡸᛂ⟅≉ᛶࡀ␗࡞ࡗࡓࠋ
඲࡚ࡢ㡿ᇦ࡛㡢ࠊẼὶ࡝ࡕࡽࡢ่⃭࡟ࡶᛂ⟅ࡍࡿከឤぬࣘࢽࢵࢺࡀグ㘓ࡉࢀࠊ㧗ḟ㒊఩࡛࠶ࡿ࢟ࣀ
ࢥయ㸦MB㸧ࡸ୰ᚰ」ྜయ㸦CX㸧࡛ከ࠿ࡗࡓࠋࡲ
ࡓẼὶࡢࡳ࡟ᛂ⟅ࡍࡿࣘࢽࢵࢺࡣ࡯࡜ࢇ࡝࡞࠿ࡗ
ࡓࡇ࡜࠿ࡽ㺂Ẽὶឤぬධຊࡣ௚ࡢឤぬ࡜⤫ྜࡉࢀࡸࡍ࠸࡜⪃࠼ࡽࢀࡿࠋ
᪉ྥឤཷᛶࢆࡼࡾከゅⓗ࡟ẚ㍑ࡍࡿࡓࡵ㺂ከḟඖᑻᗘᵓᡂἲ㸦MDS㸧ࢆ⏝࠸࡚᪉ྥࢳ࣮ࣗࢽࣥࢢ
࣮࢝ࣈࡢᙧ≧ࢆゎᯒࡋࡓࠋࡑࡢ⤖ᯝ㺂ྛࣘࢽࢵࢺࡢ
ࢳ࣮ࣗࢽࣥࢢ࣮࢝ࣈࡣ㺂ࡑࡢ㗦ࡉࢆ➨ 1 せ⣲࡜ࡋ࡚ࠊከᓠᛶࡢᗘྜ࠸ࢆ➨ 2 せ⣲࡜ࡋ࡚஧ḟඖᖹ㠃ୖ࡟ྍど໬ࡉࢀࡓࠋ᪉ྥࢳ࣮ࣗࢽࣥࢢࢆ่⃭✀㛫࡛ẚ㍑ࡍࡿ࡜ࠊ⫈ぬᛂ⟅ࡢ᪉ྥ㑅ᢥᛶࡣẼὶᛂ⟅࡟ẚ࡭࡚㧗࠿ࡗࡓࠋࡋ࠿ࡋ㺂ከឤぬࢽ࣮ࣗࣟࣥ࡟࠾
࠸่࡚⃭✀࡟ࡼࡿ᪉ྥ㑅ᢥᛶࡢ㐪࠸ࢆẚ㍑ࡋࡓ࡜
ࡇࢁ㺂ྠ୍ࣘࢽࢵࢺ࡛࠶ࡗ࡚ࡶࢳ࣮ࣗࢽࣥࢢ≉ᛶࡣ㢮ఝࡋ࡚࠸࡞࠿ࡗࡓࠋ୍᪉㺂⬻㡿ᇦ㛫࡛ẚ㍑ࡍࡿ

− 12 −

࡜㺂MB ࡸ CX ࡜ฟຊ㡿ᇦ࡛࠶ࡿഃ๪ⴥ LAL ࡣ㺂ୖ⾜ᛶࢽ࣮ࣗࣟࣥࡢᢞᑕ㡿ᇦࡼࡾࡶከᵝ࡞ࢳ࣮ࣗࢽ
ࣥࢢ≉ᛶࢆࡶࡘᛂ⟅ࡀグ㘓ࡉࢀࡓࠋ௨ୖࡢ⤖ᯝ࠿ࡽ㺂Ẽὶ่⃭࡜㡢่⃭ࡢ᪉ྥ᝟ሗࡣูࠎ࡟ฎ⌮ࡉࢀ࡚࠾ࡾࠊከឤぬࢽ࣮࡛ࣗࣟࣥ࠶ࡗ࡚ࡶ␗✀่⃭㛫ࡢ᪉ྥ᝟ሗࡣඹ᭷ࡉࢀ࡚࡞࠸ࡇ࡜ࡀࢃ࠿ࡗࡓࠋ
⫈ぬ่⃭࡜Ẽὶ่⃭ࢆྠ᫬࡟ᥦ♧ࡋ㺂␗✀ឤぬ่⃭࡟ᑐࡍࡿከឤぬࢽ࣮ࣗࣟࣥᛂ⟅ࡢຍ⟬≉ᛶ࡜᪉ྥឤཷᛶࢆㄪ࡭ࡓࠋࡑࡢ⤖ᯝ㺂ྠ᫬ᥦ♧࡟ᑐࡍࡿከឤぬᛂ⟅ࡣࠊࡑࢀࡒࢀࡢ่⃭ࢆ⊂❧ࡋ࡚୚࠼ࡓ
ሙྜࡢᛂ⟅ࡢ⥺ᙧຍ⟬࡜᭷ព࡟ኚࢃࡽ࡞࠸ࡶࡢ㺂⥺ᙧຍ⟬ࡼࡾࡶ኱ࡁࡃ࡞ࡿࡶࡢ㺂⥺ᙧຍ⟬ࡼࡾᑠࡉࡃ࡞ࡿࡶࡢࡢ࠸ࡎࢀࡶࡀほ ࡉࢀࡓࠋࡲࡓ㺂ከឤぬᛂ⟅ࡢ᪉ྥឤཷᛶࢆ⥺ᙧຍ⟬ࡋࡓࡶࡢ࡜ MDS
࡛ẚ㍑ࡋࡓ࡜ࡇࢁ㺂஫࠸࡟㢮ఝࡋ࡚࠸ࡓࠋࡋࡓࡀࡗ
࡚㺂⬻ෆከឤぬࢽ࣮ࣗࣟࣥࡣ㡢࡜Ẽὶࢆྠ᫬࡟ཷ
ᐜࡍࡿࡇ࡜࡛ឤཷᛶࡀ㠀⥺ᙧ࡟ኚ໬ࡍࡿࡀࠊࡑࡢ
ኚ໬ࡣ඲᪉ྥ࡟ᑐࡋ࡚⏕ࡌࡿࡓࡵ࡟㺂᪉ྥ㑅ᢥᛶࡀࡑࢀ࡯࡝ኚࢃࡽ࡞࠸࡜⪃࠼ࡽࢀࡿࠋ
௨ୖࡲ࡜ࡵࡿ࡜㺂ࢥ࢜ࣟࢠ⬻ෆ࡟ࡣୖ⾜ᛶࢽ࣮ࣗࣟࣥࡼࡾࡶ」㞧࡞᪉ྥ㑅ᢥᛶࢆ♧ࡍࢽ࣮ࣗࣟࣥ
ࡀᏑᅾࡋ㺂㧗ḟฎ⌮㡿ᇦ࡯࡝ከᵝ໬ࡋࡓࠋከឤぬࢽ࣮࡛ࣗࣟࣥ࠶ࡗ࡚ࡶ่⃭✀࡟ࡼࡗ࡚᪉ྥ㑅ᢥᛶࡣ␗࡞ࡾ㺂⫈ぬ่⃭࡜Ẽὶ่⃭ࢆྠ᫬࡟ཷᐜࡍࡿ࡜
ᛂ⟅ࡢ኱ࡁࡉࡀኚ໬ࡋࡓࠋⓎ⾲ㄽᩥ1) Sato, N., Shidara, H., Ogawa, H. (2019)
Trade-off between motor performance andbehavioural flexibility in the action selection ofcricket escape behaviour. Scientific Reports, 9: 18112.
ⴭ᭩ᑠᕝᏹே㸪ୖᕝෆ࠶࡙ࡉ㸦2019㸧1㸧 ᰁ㇂┿⍆㸪ᑠ
8-5 ୰ᯡࡢാࡁ inࠕ⏕ࡁ≀࡜㡢ࡢ஦඾ࠖ⏕≀㡢㡪Ꮫ఍ ⦅ Pp 302-303, ᮅ಴᭩ᗑ⥲ㄝ࣭ゎㄝ
1㸧 ᑠᕝᏹே㸪⚟ᐩཪ୕㑻㸪ᰁ㇂┿⍆㸦2019㸧ࢥ࢜ࣟࢠࡢ⫈ぬ่⃭࡟ࡼࡿ⏕ᚓⓗ⾜ືࡢಟ㣭࡜ࡑࡢ⚄⤒ᇶ┙ ㉸㡢Ἴ TECHNO 31: 1-4
ᅜ㝿఍㆟Ⓨ⾲1㸧 Ogawa, H., Tanaka, K., Someya, M., Shidara, H.
(2019)
Different cell groups encode stimulus intensity anddirection in insect mechanosensory system.
49th Annual Meeting of Society for Neuroscience,
McCormick Place㸦Chicago㸧
2㸧 Kai, K., Shidara, H., Ando, N., Ogawa, H. (2019)
Neural activity in the central complex of the crickets
during phonotaxis.

49th Annual Meeting of Society for Neuroscience,
McCormick Place㸦Chicago㸧
3㸧 Shidara, H., Ogawa, H. (2018)
Role of GABAergic inhibitory inputs on dendritic
integration for wind direction-selectivity in theinsect’s mechanosensory projection neurons.
49th Annual Meeting of Society for Neuroscience,
McCormick Place㸦Chicago㸧ᅜෆᏛ఍Ⓨ⾲1㸧 Hayashida, Y, Shidara, Y, Kai, K., Ogawa, H.㸦2019㸧
Directional tuning characteristics of multisensory
neurons in the cricket brain.
᪥ᮏẚ㍑⏕⌮⏕໬Ꮫ఍➨ 41 ᅇ኱఍㸪ᮾி኱Ꮫ㸦ᮾி㒔┠㯮༊㸧ᑠᕝᏹே㸦2019㸧2㸧 బ⸨࿴㸪ᑠࢥ࢜ࣟࢠࡢ⏕ᚓⓗ㏨㑊⾜ື࡟࠾ࡅࡿ␗࡞ࡿᡓ␎
㛫ࡢࢺ࣮ࣞࢻ࣭࢜ࣇ
᪥ᮏື≀Ꮫ఍➨ 90 ᅇ኱㜰኱఍㸪኱㜰኱Ꮫ㸦኱㜰ᕷ㸧ᑠᕝᏹே㸦2019㸧3㸧 ᮏ୸ᑦே㸪タᵹஂᚿ㸪ᑠࢥ࢜ࣟࢠࡢ㡢※ᐃ఩ࢼࣅࢤ࣮ࢩࣙࣥ࡟࠾ࡅࡿ᥋
㏆ࣇ࢙࣮ࢬࡢゎᯒ᪥ᮏື≀Ꮫ఍➨ 90 ᅇ኱㜰኱఍㸪኱㜰኱Ꮫ㸦኱㜰ᕷ㸧
4㸧 ᑠᕝᏹே㸪⏣୰ᑑᕼ, ᰁ㇂┿⍆, タᵹஂᚿ㸦2019㸧᪻⹸ࡢᶵᲔឤぬ⣔࡟࠾ࡅࡿ␗࡞ࡿ่⃭᝟ሗࡢ➢ྕ໬ࢆ࡟࡞࠺⣽⬊㞟ᅋ
Neuro2019̾➨ 42 ᅇ᪥ᮏ⚄⤒⛉Ꮫ኱఍࣭➨ 62 ᅇ᪥ᮏ⚄⤒໬Ꮫ఍኱఍ྜྠ኱఍̾ࠊᮒ㮛࣓ࢵࢭ㸦᪂₲ᕷ㸧⏕≀⛉Ꮫ㒊㒊㛛 ⾜ື⚄⤒⏕≀Ꮫศศ㔝ỈἼ ㄔ ࣡ࣔࣥࢦ࢟ࣈࣜࡢႥぬ୰ᯡࡢ୪ิⓗ࡞᝟ሗฎ⌮⤒㊰ࡢゎ᫂
᪻⹸㸦࣡ࣔࣥࢦ࢟ࣈࣜ㸧ࡢ⬻ࡢ㧗ḟႥぬ୰ᯡ㸦࢟ࣀࢥయ㸧࡟ᢞᑕࡍࡿᢚไᛶࢽ࣮ࣗࣟࣥ࡟╔┠ࡋࠊࡑࢀࡽࡀ࢟ࣀࢥయฟຊࢽ࣮ࣗࣟࣥ࠿ࡽࢩࢼࣉࢫࢆ
ཷࡅ࡚࢟ࣀࢥయࡢฟຊࢽ࣮ࣗࣟࣥࡢໝ࠸ᛂ⟅ࡢᙉᗘࢆ㐺ṇ࡞ࣞ࣋ࣝ࡟ㄪ⠇ࡍࡿ㈇ࡢࣇ࢕࣮ࢻࣂࢵ
ࢡ⤒㊰ࢆᢸࡗ࡚࠸ࡿࡇ࡜ࢆ✺ࡁṆࡵࡓࠋࡉࡽ࡟
࢟ࣀࢥయࡢࣇ࢕࣮ࢻࣂࢵࢡ⤒㊰࡟ࡣໝ࠸ཷᐜࢽ
࣮ࣗࣟࣥࡢࢱ࢖ࣉࡢ㐪࠸࡟⏤᮶ࡍࡿ  ࡘࡢ୪ิⓗ࡞⤒㊰ࡀ࠶ࡿࡇ࡜ࡲࡓ  ࡘࡢ୪ิ⤒㊰ࡢ㛫࡟┦஫స⏝ࡀ࠶ࡿࡇ࡜ࢆぢฟࡋࡓࠋࡇࡢⓎぢࡣື≀ࡢႥぬ⣔࡟࠾࠸࡚ཷᐜࢽ࣮ࣗࣟࣥ࠿ࡽ㧗ḟ୰ᯡ࡟⮳ࡿࡲ୍࡛㈏ࡋࡓ୪ิⓗ࡞᝟ሗฎ⌮⤒㊰ࡀಖࡓࢀ࡚࠸ࡿࡇ࡜ࢆึࡵ࡚᫂ࡽ࠿࡟ࡋࡓࡶࡢ࡛ࣄࢺ
࡞࡝့ங㢮ࡢ⬻ࡢႥぬ᝟ሗฎ⌮⣔ࡢᇶᮏᵓᡂࡢ⌮ゎ࡟ࡶ♧၀ࢆ୚࠼ࡿ㔜せ࡞ᡂᯝ࡛࠶ࡿࠋ௒ᚋࡣࠊ
࣡ࣔࣥࢦ࢟ࣈࣜࡢ࢟ࣀࢥయ࡟࠾ࡅࡿ୪ิ⤒㊰࠾ࡼࡧ୧⤒㊰㛫ࡢ┦஫స⏝࡟࡝ࡢࡼ࠺࡞ᶵ⬟ⓗ࡞ព࿡− 13 −

ࡀ࠶ࡿ࠿ࡢゎ᫂࡟ྲྀࡾ⤌ࡳࡓ࠸ࠋ
㸬ࢦ࢟ࣈࣜࡢ㉸㧗ឤᗘࣇ࢙ࣟࣔࣥཷᐜࢩࢫࢸ࣒ࡢ
ゎ᫂ࢺࣝ࢟ࢫࢱࣥࢦ࢟ࣈࣜࡢ࢜ࢫࡢゐゅⴥ࡟ࡣᛶࣇ࢙
ࣟࣔࣥࢆᑓ⏝࡟ฎ⌮ࡍࡿᕧ኱࡞⣒⌫యࡀ࠶ࡿࠋᮏ
✀ࡢయࡢ኱ࡁࡉࡣ࣡ࣔࣥࢦ࢟ࣈࣜࡢ  ࡯࡝ࡔࡀࠊ
ࣇ࢙ࣟࣔࣥ⣒⌫యࡢయ✚ࡣ࣡ࣔࣥࢦ࢟ࣈࣜࡢ┦ྠ⣒⌫యࡢ  ಸ࡛࠶ࡿࠋࡇࡢࡇ࡜ࡣࠊᛶࣇ࢙ࣟࣔࣥ
ࢆ≉␗ⓗ࡟ฎ⌮ࡍࡿឤぬ⣽⬊ࡢᩘࡀ࣡ࣔࣥࢦ࢟ࣈ
ࣜࡼࡾࡶከ࠸ࡇ࡜ࢆ♧၀ࡍࡿࠋࡇࡢᕧ኱⣒⌫య࠿ࡽฟຊࡍࡿ௓ᅾ⚄⤒ࡢᛂ⟅࡟ࡘ࠸࡚ㄪ࡭ࡓ࡜ࡇࢁࠊ
࣌ࣜࣉࣛࣀࣥ࡟ᑐࡋ㠀ᖖ࡟ᙉ࠸⯆ዧᛶᛂ⟅ࢆ♧ࡍࡇ࡜ࡀࢃ࠿ࡗࡓࠋࡑࡢࣇ࢙ࣟࣔࣥࢆゐゅ࡟᥋ゐࡉࡏࡓ࡜ࡁ࡟⚄⤒ࡀ⯆ዧࡍࡿ᭱ᑠࡢࣇ࢙ࣟࣔࣥ⃰ᗘࡣ  ࣇ࢙࣒ࢺࢢ࣒࡛ࣛࠊ࣡ࣔࣥࢦ࢟ࣈࣜࡢ┦ྠ࡞⚄⤒ࡢ  ಸ௨ୖࡢឤᗘ࡛࠶ࡗࡓࠋࡇࢀࡣࠊໝ
࠸࡟ᑐࡍࡿ⚄⤒ࡢឤᗘ࡜ࡋ࡚ࡣࠊࡇࢀࡲ࡛▱ࡽࢀ࡚࠸ࡿື≀ࡢ୰࡛᭱㧗࡛࠶ࡗࡓࠋཎⴭㄽᩥ1) Takahashi N, Nishino H, Domae M, Mizunami M.
(2019). Separate but interactive parallel olfactory
processing streams governed by different types of
GABAergic feedback neurons in the mushroom
body of a basal insect. J. Neurosci. 39: 8690-8704.
2) Domae M., Iwasaki M., Mizunami M. and Nishino
H. (2019). Functional unification of sex
pheromone-receptive glomeruli in an invasive
cockroach derived from the genus Periplaneta.
Neurosci. Lett.708: 134320.
3) Mizunami M., Hirohata S., Sato A., Arai R., Terao
K., Sato M. and Matsumoto Y. (2019).
Development of behavioral automaticity byextended Pavlovian training in an insect. Proc. R.
Soc. B. 286: 21182132.
ⴭ᭩1) 26) Mizunami M and Alvarez B (2019) Pavlovian
conditioning in invertebrates. In: Encyclopedia of
Animal Behavior. 2nd edition, Ed By Choe J.
Elsevier, Oxford. Pp403-410.
㒊㛛 ⾜ື⚄⤒⏕≀Ꮫศศ㔝⏕≀⛉Ꮫ㒊໭⏣ ୍༤ ࣄࢺࢤࣀ࣒࡟ࡣ 2 ୓ಶ⛬ᗘࡢ㑇ఏᏊࡀᏑᅾࡍࡿ
ࡀࠊࡑࡢ࠺ࡕ⣙ 2,000 ಶࡢ㑇ఏᏊࡀ⢭Ꮚᙧᡂ࡟㛵୚ ࡍ ࡿ ࡜ ሗ ࿌ ࡉ ࢀ ࡚ ࠸ ࡿ 㸦 Csilla Krausz,et. al,
Nature Review Urology, 2018㸧ࠋࡋ࠿ࡋࠊࡑࡢከࡃࡣ
ᶵ⬟ゎᯒࡀ㐍ࢇ࡛࠾ࡽࡎࠊ୙ዷ⑕ࡢ⑓ᅉ࣭⑓ែࢆ
ゎ᫂ࡍࡿ࠺࠼࡛㞀ᐖ࡜࡞ࡗ࡚࠸ࡿࠋ௒ᅇഅ↛࡟ࠊ๗᳨࡟࡚ ICR ࣐࢘ࢫࡢྠ୍ࣜࢵࢱ࣮ෆ࡛ࠊ㞝࡟࠾࠸࡚⢭ᕢⴎ⦰ࢆ♧ࡍ」ᩘࡢಶయࢆぢฟࡋࡓࠋࡑࡇ

࡛ࠊ⑓⌮⤌⧊Ꮫⓗ᳨⣴ࢆ⾜ࡗࡓ࡜ࡇࢁࠊ෇ᙧ⢭Ꮚ⣽⬊ࡢ⵳✚࡜ᕧ኱ከ᰾⣽⬊ࡢฟ⌧ࡀほᐹࡉࢀࠊ➨୍ῶᩘศ⿣ᮇࡢᰁⰍయศ㓄࡟ఱࡽ࠿ࡢ␗ᖖࢆ࿊ࡋ
࡚࠸ࡿࡇ࡜ࡀ᥎ᐹࡉࢀࡓࠋ௒ᚋࠊ஺㓄ヨ㦂ࢆᐇ᪋ࡋ࡚㑇ఏᛶࢆ☜ㄆࡍࡿணᐃ࡛࠶ࡿࡀࠊࡑࢀ࡟ඛ❧ࡕࣉ࣑ࣞࣜࢼࣜ࡟ 1 ༉ࡢ␗ᖖಶయ࠿ࡽࢤࣀ࣒ DNA
ࢆᢳฟࡋ࡚ࠊReseq ゎᯒࢆᐇ᪋ࡋࡓࠋGATK ࣃࢵࢣ࣮ࢪࢆ⏝࠸࡚ C57BL/6J ࡜ࡢ㛫ࡢኚ␗ࢆࢥ࣮ࣝࡋ
ࡓ࡜ࡇࢁࠊࡇࡢಶయ࡛࣍ࣔ࡟ᣢࡗ࡚࠸ࡿ࡜ࢥ࣮ࣝ
ࡉࢀࡓ SNP ࡣ 6,722,421 ಶࠊindel ࡣ 1,773,844 ಶ࡟ୖࡗࡓࡀࠊ᪤࡟ dbSNP ࢹ࣮ࢱ࣮࣋ࢫ࡟Ⓩ㘓ࡉࢀ࡚࠸ࡿኚ␗ࢆ㝖እࡋࡓ࡜ࡇࢁࠊSNP ࡣ 231,919 ಶࠊ
indel ࡣ 623,228 ಶࡢࡳ࡟⤠ࡿࡇ࡜ࡀ࡛ࡁࡓࠋSnpEff࡟࡚࢔ࣀ࣮ࢸ࣮ࢩࣙࣥࢆ⾜࠸ࠊ⩻ヂ㡿ᇦ࡟
frameshift ࡀ᳨ฟࡉࢀࡓ㑇ఏᏊࡣ 267 ಶ࡛࠶ࡾࠊࡑ
ࡢ࠺ࡕ 21 ᪥㱋ࡢ⢭ᕢ࡛㧗Ⓨ⌧ࡋࠊ࠿ࡘ㸵᪥㱋࡛ࡣ㧗Ⓨ⌧ࡋ࡞࠸㑇ఏᏊࡣ 10 ಶࡢࡳ࡛࠶ࡗࡓࠋࡇࡢ࠺
ࡕ Hils1 㑇ఏᏊ࡟ࡘ࠸᳨࡚⣴ࡋࡓࡀࠊ୙ዷಶయࡔࡅ
࡛࡞ࡃዷᛶಶయ࠿ࡽࡶ࣍ࣔࡢኚ␗ࡀ᳨ฟࡉࢀࡓࡓ
ࡵࠊೃ⿵㑇ఏᏊ࠿ࡽ㝖እࡋࡓࠋ⩻ヂ㡿ᇦ࡟ࢼࣥࢭ
ࣥࢫኚ␗ࡀ᳨ฟࡉࢀࡓ㑇ఏᏊࡣ 5 ಶ࡛࠶ࡾࠊࡇࡢ
࠺ࡕ Skint6 㑇ఏᏊ࡟࠾ࡅࡿኚ␗ W168stop ࡟ࡘ࠸࡚ࡣ࣐࢘ࢫ lupus ឤཷᛶࡢೃ⿵࡛࠶ࡿࡇ࡜ࡀሗ࿌ࡉ
ࢀ࡚࠾ࡾ㸦Genes Immun. 2017 Sep;18(3):111-117.㸧
ࠊ୙ዷࡢೃ⿵㑇ఏᏊ࠿ࡽ㝖እࡋࡓࠋ⌧ᅾࡣࠊ࣑ࢫࢭ
ࣥࢫኚ␗࡟ࡘ࠸࡚ࠊ᳨⣴ࢆ⥆⾜ࡋ࡚࠸ࡿࠋ
㒊㛛 ⾜ື⚄⤒⏕≀Ꮫศศ㔝⏕≀⛉Ꮫ㒊࿴ከ ࿴ᏹ
◊✲⤖ᯝ㡢ኌⓎኌᏛ⩦ࡢ⮫⏺ᮇไᚚཬࡧࠊ✀≉␗ⓗ࡞Ⓨኌࣃࢱ࣮ࣥ⏕ᡂ࡟㛵ࢃࡿ㑇ఏᏊ⩌ࢆ᫂ࡽ࠿࡟ࡋࠊ
ࡑࡢ⬻ෆศᏊᶵ⬟ࢆ⚄⤒⾜ືᏛⓗ࡟᳨ドࡍࡿࡇ࡜ࢆ┠ⓗ࡜ࡋ࡚◊✲ࢆ㐍ࡵ࡚࠸ࡿࠋࡑࡢࡓࡵ࡟ື≀ࣔࢹࣝ࡜ࡋ࡚㬆⚺㢮ࢯࣥࢢࣂ࣮ࢻࢆ⏝࠸ࡓ◊✲ࢆ᪋⾜ࡋ࡚࠸ࡿࠋࣄࢺࡢゝㄒࡸᑠ㫽ࡢḷࡣࠊぶ࡞࡝௚ಶయࡢⓎኌࣃࢱ࣮ࣥࢆࡲࡡࡿࡇ࡜࡛ᚋኳⓗ࡟⋓ᚓࡉࢀࡿࠋࡇࡢⓎኌᏛ⩦࡟ࡣࠊᏛ⩦ࡀຠ⋡ࡼࡃ㐍ࡴ᫬ᮇࠊࡍ࡞ࢃࡕᏛ⩦⮫⏺ᮇ㸦ឤཷᛶᮇ㸧ࡀ࠶ࡿࡇ࡜ࡀ▱ࡽࢀ࡚࠸ࡿࠋࡋ࠿ࡋ㸪⬻ෆ࡛ⓎኌᏛ⩦ࡢ⮫⏺ᮇࡀ⤊஢ࡍࡿ࣓࢝ࢽࢬ࣒ࡣṤ࡝᫂ࡽ࠿࡟ࡉࢀ
࡚࠸࡞࠸ࠋࡲࡓࠊ✀≉␗ⓗ࡞ⓎኌᏛ⩦࡟㛵ࢃࡿ⚄⤒ศᏊᇶ┙ࡶ඲ࡃศ࠿ࡗ࡚࠸࡞࠸ࠋ
௒ᖺᗘࡣࠊ㏆⦕✀࡛࠶ࡿ࢟ࣥ࢝ࢳࣙ࢘࡜࢝ࣀࢥ
ࢫࢬ࣓ࢆ⏝࠸࡚ࠊ㑇ఏᏊࡢㄞࡳฟࡋ᪉㸦㑇ఏᏊⓎ⌧ไᚚ㸧ࡀ࡝ࡢࡼ࠺࡟⬻ෆ࡛ኚࢃࡗࡓࡇ࡜࡛✀≉␗ⓗ࡞ḷࣃࢱ࣮ࣥࡀ⏕ࡲࢀࡓࡢ࠿ࢆ᫂ࡽ࠿࡟ࡋࡓࠋ
ࡇࡢ 2 ✀ࡣ㏆⦕✀࡟ࡶ࠿࠿ࢃࡽࡎࠊࡉ࠼ࡎࡾḷࡀ኱ࡁࡃ␗࡞ࡾࠊࡲࡓ㏆⦕✀ࡺ࠼࡟㞧✀ࣁ࢖ࣈࣜࢵ
ࢻಶయࢆసࡾฟࡏࡿࠋࡇࡢ㏆⦕✀ 2 ✀㛫࡛ࡢࠕ㑇− 14 −

ఏᏊࡢㄞࡳฟࡉࢀ࡚࠸ࡿ㔞ࠖ࡜ࡑࡢᏊᏞࡢ F1 ࣁ࢖ࣈࣜࢵࢻಶయ࡛ࡢࠕ㑇ఏᏊᗙࡢㄞࡳฟࡋẚࠖࡢ 2ࡘࡢ᝟ሗ࠿ࡽࠊࢤࣀ࣒ୖࡢྛ㑇ఏᏊࡢㄞࡳฟࡋ࡟
㛵ࢃࡿኚ␗ࡢ᭷↓ࢆุᐃࡋࡓࠋࡑࡢ⤖ᯝࠊࡉ࠼ࡎ
ࡾⓎኌ࡟㔜せ࡞⬻㒊఩㸦ḷ⚄⤒᰾㸧࡛⣙ 800 ಶࡢ㑇ఏᏊ࡛ࡑࡢㄞࡳฟࡋ࡟㛵ࢃࡿኚ␗ࡀ㉳ࡇࡿࡇ࡜ࡀศ࠿ࡗࡓࠋࡇࢀࡣ⬻ෆ࡛ㄞࡳฟࡉࢀ࡚࠸ࡿ㑇ఏᏊࡢ⣙ 10㸣ࡀᙳ㡪ࢆཷࡅ࡚࠸ࡿࡇ࡜ࢆព࿡ࡍࡿࠋ
≉࡟ࠊ㑇ఏᏊࡢㄞࡳฟࡋㄪ⠇࡟㛵ࢃࡿᅉᏊࡢᛶ㉁ࢆኚ࠼ࡿ trans ኚ␗࡟ࡼࡗ࡚ࠊ⚄⤒ᶵ⬟࡟㛵ࢃࡿ㑇ఏᏊ⩌ࡀከࡃࡢᙳ㡪ࢆཷࡅ࡚࠸ࡓࠋࡇࡢ㸰✀㛫࡛␗࡞ࡿㄞࡳฟࡋㄪ⠇࡟㛵ࢃࡿᅉᏊ࡜ࡋ࡚ࠊ⬻⏤᮶⚄⤒ᰤ㣴ᅉᏊ࡜ࡋ࡚▱ࡽࢀࡿ BDNF ࢆྠᐃࡋࡓࠋᐇ㝿࡟ BDNF సື⸆ࢆ࢟ࣥ࢝ࢳࣙ࢘ࡢ⬻ෆ࡟ධࢀࡿ࡜ࠊtrans ኚ␗ࢆཷࡅ࡚࠸ࡿ㑇ఏᏊ⩌ࡢㄞࡳฟࡋ᪉ࡀኚࢃࡗࡓࠋࡲࡓࠊBDNF సື⸆ࢆ㸰㐌㛫ᢞ୚ࡉࢀࡓ࢟ࣥ࢝ࢳࣙ࢘ࡣࠊᮏ᮶ࡢ࢟ࣥ࢝ࢳࣙ࢘
ࡢ≉㛗ࢆࡶࡘࡉ࠼ࡎࡾḷࣃࢱ࣮ࣥࡀᔂࢀ࡚␗ᖖ࡞
ḷࢆḷ࠺ࡼ࠺࡟࡞ࡿࡇ࡜ࢆᐇ㦂ⓗ࡟᳨ドࡋࡓࠋㄽᩥⓎ⾲
Wang H, Sawai A, Toji N, Sugioka R, Shibata Y,
Suzuki Y, Ji Y, Hayase S, Akama S, Sese J, Wada K.
Transcriptional regulatory divergence underpinningspecies-specific learned vocalization in songbirds.
PLoS Biology 17:e3000476. 2019
Sánchez-Valpuesta M, Suzuki Y, Shibata Y, Toji N, Ji Y,
Afrin N, Asogwa CN, Kojima I, Mizuguchi D, Kojima
S, Okanoya K, Okado H, Kobayashi K, Wada K.
Corticobasal ganglia projecting neurons are required
for juvenile vocal learning but not for adult vocal
plasticity in songbirds. PNAS 116:22833-22843. 2019Ꮫ఍Ⓨ⾲
ᰘ⏣ࡺࡁ㔝ࠊ࿴ከ࿴ᏹ: ␗✀㛫ࣁ࢖ࣈࣜࢵࢻࢯࣥ
ࢢࣂ࣮ࢻ࡟࠾ࡅࡿḷᏛ⩦⬟ຊ. ᪥ᮏື≀Ꮫ఍ ➨90 ᅇ኱఍, 2019 ᖺ 9 ᭶ 14 ᪥ ኱㜰ᕷ ኱㜰ᕷ❧኱Ꮫ࿴ከ࿴ᏹࠊWANG Hongdi: Ꮫ⩦࡟ࡼࡗ࡚⋓ᚓࡉࢀࡿ✀≉␗ⓗ࡞Ⓨኌࣃࢱ࣮ࣥ⏕ᡂ࡟㛵ࢃࡿ㑇ఏᏊⓎ⌧ไᚚ࣓࢝ࢽࢬ࣒. ᪥ᮏ⏕໬Ꮫ఍ ➨ 92 ᅇ኱఍,2019 ᖺ 9 ᭶ 20 ᪥, ᶓ὾ ࣃࢩࣇ࢕ࢥᶓ὾
Hongdi Wang, Azusa Sawai, Noriyuki Toji, Rintaro
Sugioka, Yukino Shibata, Yuika Suzuki, Yu Ji, Shin
Hayase, Satoru Akama, Jun Sese, Kazuhiro Wada:
Transcriptional regulatory divergence underpinningspecies-specific learned vocalization in songbirds.
Society for Neuroscience meeting, 2019, October 20,
Chicago, USA.
Yu Ji; Miguel Sánchez-Valpuesta; Kazuhiro Wada:
Regulation of repetitive syllable sequence by the
excitatory and inhibitory balance in the basal ganglia
song nucleus in songbirds. Society for Neuroscience

meeting, 2019, October 20, Chicago, USA.
㒊㛛 ⏕ṪⓎ⏕⏕≀Ꮫ
Ꮫศ㔝
⏕≀⛉Ꮫ㒊
㯮ᒾ 㯞㔛
⚾ࡓࡕࡀ◊✲ᑐ㇟࡜ࡋ࡚࠸ࡿ࢔࣐࣑ࢺࢤࢿࢬ࣑
(Tokudaia osimensis) ࡜ ࢜ ࢟ ࢼ ࣡ ࢺ ࢤ ࢿ ࢬ ࣑(Tokudaia muenninki) ࡣࠊࡑࡢᛶᰁⰍయ࡜ᛶỴᐃࡢศᏊ࣓࢝ࢽࢬ࣒࡟ࣘࢽ࣮ࢡ࡞≉ᚩࢆࡶࡘࠋࡑࡇ࡛ࠊ
ࢺࢤࢿࢬ࣑ᒓࡢᛶᰁⰍయ㐍໬ࡢ㐣⛬࠾ࡼࡧᛶỴᐃศᏊ࣓࢝ࢽࢬ࣒ࢆ᫂ࡽ࠿࡟ࡍࡿࡇ࡜ࢆ┠ⓗ࡜ࡋ࡚ࠊ㸰✀ࡢ෾⤖⥺⥔ⱆ⣽⬊ࢆᮏࢭࣥࢱ࣮すᲷ࡟࡚ಖᏑ
ࡋ࡚࠸ࡿࠋࡲࡓࠊ㸰✀ࡢ BAC ࣛ࢖ࣈ࣮ࣛࣜࢆస〇ࡋࠊྠࡌࡃすᲷ࡟࡚ಖ⟶ࡋ࡚࠸ࡿࠋಖ⟶ࡋ࡚࠸ࡿ
BAC ࣛ࢖ࣈ࣮ࣛࣜࡣࠊ࢔࣐࣑ࢺࢤࢿࢬ࣑ࡀ 384 ࢙࢘ࣝࣉ࣮ࣞࢺ 255 ᯛࠊ࢜࢟ࢼ࣡ࢺࢤࢿࢬ࣑ࡀ 384
࢙࢘ࣝࣉ࣮ࣞࢺ 420 ᯛ࡛࠶ࡿࠋࡇࢀࡽࡢ BAC ࣛ࢖ࣈ࣮ࣛࣜࡣ⊂❧⾜ᨻἲே ⌮໬Ꮫ◊✲ᡤ ච␿࣭࢔ࣞࣝࢠ࣮⛉Ꮫ ⥲ྜ◊✲ࢭࣥࢱ࣮㸦⚄ዉᕝ┴ᶓ὾ᕷ㸧࡛సᡂࠊಖᏑࡉࢀ࡚࠸ࡓࡶࡢ࡛࠶ࡿࠋᕼᑡ࡞
ࢧࣥࣉࣝࢆ᪥ᮏྛᆅ࡟ศᩓࡉࡏࠊ⅏ᐖ᫬ࡢᦆኻࢆ
᭱ᑠ㝈࡟ᢚ࠼ࡿ┠ⓗ࠿ࡽࡶࠊᙜࢭࣥࢱ࣮࡟࡚ಖ⟶ࡋ࡚࠸ࡿࠋ ᮏᖺᗘࡣࠊ≉࡟ࢺࢤࢿࢬ࣑ᒓ࡟࠾ࡅࡿ X ᰁⰍయ୙άᛶ໬ᶵᵓ࡟ࡘ࠸࡚᫂ࡽ࠿࡟ࡍࡿࡓࡵ࡟ࠊ࢜࢟
ࢼ࣡ࢺࢤࢿࢬ࣑ࡢ෾⤖⥺⥔ⱆ⣽⬊࠾ࡼࡧ BAC ࣛ࢖ࣈ࣮ࣛࣜࢆ฼⏝ࡋࡓࠋXX/XY ᆺࡢ࢜࢟ࢼ࣡ࢺࢤ
ࢿࢬ࣑࡛ࡣࠊX ࠾ࡼࡧ Y ᰁⰍయ࡟୍ᑐࡢᖖᰁⰍయ
ࡀ⼥ྜࡍࡿࡇ࡜࡛ࠊneo-X, Y ᰁⰍయࢆ⋓ᚓࡋ࡚࠸ࡿࡇ࡜ࡀࠊ⚾ࡓࡕࡢඛ⾜◊✲࠿ࡽ᫂ࡽ࠿࡟࡞ࡗ࡚
࠸ࡿࠋ᭱㏆⋓ᚓࡉࢀࡓ neo-X ᰁⰍయࡀࠊ࣓ࢫࡢయ
⣽⬊ෆ࡛୙άᛶ໬ࡢᙳ㡪ࢆཷࡅ࡚࠸ࡿࡢ࠿ࢆ᳨ドࡍࡿࡓࡵ࡟ࠊH3K27me3 ᢠయࢆ⏝࠸࡚࢜࢟ࢼ࣡ࢺ
ࢤࢿࢬ࣑࣓ࢫࡢᰁⰍయᶆᮏ࡟ᑐࡋ࡚ච␿⤌⧊໬Ꮫゎᯒࢆ⾜࡞࠸ࠊࢡ࣐ࣟࢳࣥಟ㣭ࡢ≧ែࢆ☜ㄆࡋࡓࠋࡲࡓࠊ୍⯡ⓗ࡞့ங㢮ࡢ୙άᛶ໬ X ᰁⰍయࡣࠊᵓ
㐀ⓗ࡟จ⦰ࡋࡓࣂ࣮ᑠయ࡜࿧ࡤࢀࡿᵓ㐀ࢆ࡜ࡿࡇ࡜ࡀ▱ࡽࢀ࡚࠸ࡿࠋNeo-X ᰁⰍయࡀࣂ࣮ᑠయࡢᵓ
㐀ࢆ࡜ࡿࡢ࠿ࢆ☜ㄆࡍࡿࡓࡵ࡟ࠊneo-X ᰁⰍయୖ
ࡢ BAC ࢡ࣮ࣟࣥ 13 ✀㢮ࢆ༢㞳ࡋࠊ࢜࢟ࢼ࣡ࢺࢤ
ࢿࢬ࣑࣓ࢫࡢᰁⰍయᶆᮏ࡟ᑐࡋ࡚ BAC FISH ࢆ⾜࠸ࠊ୙άᛶ໬ X ࡢᵓ㐀ࢆ☜ㄆࡋࡓࠋࡇࢀࡽࡢ⤖ᯝ
࠿ࡽࠊneo-X ᰁⰍయࡣࠊ᏶඲࡞୙άᛶ໬ࡢᙳ㡪ࢆཷࡅ࡚࠸࡞࠸ࡇ࡜ࡀ♧၀ࡉࢀࡓࠋ ࡲࡓࠊ㫽㢮࡟࠾ࡅࡿ⏕ṪⓎ⏕Ꮫ◊✲ࢆᒎ㛤ࡍࡿࡇ࡜ࢆ┠ⓗ࡜ࡋ࡚ࠊࢤࣀ࣒ᮾᲷ࡛ࢽ࣍ࣥ࢘ࢬࣛ
(Coturnix japonica) ࢆ㣫⫱ࡋ࡚࠸ࡿࠋᮏᖺᗘࡣࠊᮏ
✀࡟࠾ࡅࡿᛶỴᐃ࠾ࡼࡧᛶศ໬㛵㐃㑇ఏᏊࡢྠᐃࠊ
ྛ㑇ఏᏊࡢⓎ⌧ᵝᘧࡢ☜ㄆࢆ⾜ࡗࡓࠋࡲࡓࠊ」ᩘ
ࡢⓎ⏕ẁ㝵࡟࠶ࡿึᮇ⏕Ṫ⭢࡟࠾࠸࡚ RNA-seq ゎᯒࢆᐇ᪋ࡋࠊᚓࡽࢀࡓࢹ࣮ࢱࢆ㞤㞝㛫࡛ẚ㍑ࡍࡿ

− 15 −

ࡇ࡜࠿ࡽࠊᛶỴᐃ࡟㛵ࢃࡿ᪂つࡢ㑇ఏᏊࡢྠᐃࢆ
ヨࡳࡓࠋࡑࡢ⤖ᯝࠊW ᰁⰍయୖ࡟఩⨨ࡍࡿ
non-coding RNA ࠾ࡼࡧ protein-coding 㑇ఏᏊ 16 ✀㢮ࢆྠᐃࡋࡓࠋࡉࡽ࡟ࠊࡇࢀࡽ㑇ఏᏊࡢᶵ⬟ゎᯒࡢᡭẁ࡜ࡋ࡚ࠊCRISPR/Cas9 ࡢ⣔ࢆ⏝࠸ࡓࢤࣀ࣒
⦅㞟ᢏ⾡ࢆ☜❧ࡋࠊW ᰁⰍయୖࡢ㑇ఏᏊ࡟ࡘ࠸࡚
ࡶࢤࣀ࣒⦅㞟࡟ࡼࡿࣀࢵࢡ࢔࢘ࢺゎᯒࡀྍ⬟࡛࠶ࡿࡇ࡜ࢆ☜ㄆࡋࡓࠋࡲࡓࠊᖜᗈ࠸ື≀✀࡟࠾࠸࡚⏕Ṫ⣽⬊࡟Ⓨ⌧ࡍࡿࡇ࡜ࡀ▱ࡽࢀ࡚࠸ࡿ DAZL 㑇ఏᏊ࡟ࡘ࠸࡚Ⓨ⌧ゎᯒࢆ⾜࡞ࡗࡓ࡜ࡇࢁࠊࢽ࣍ࣥ
࢘ࢬ࡛ࣛࡣᮏ㑇ఏᏊࡢ㌿෗⏘≀࡟」ᩘࡢࣂࣜ࢔ࣥ
ࢺࡀ᳨ฟࡉࢀࠊࡉࡽ࡟ࡑࡢ✀㢮࡟ᛶᕪࡀ࠶ࡿࡇ࡜
ࡀ☜ㄆࡉࢀࡓࠋຍ࠼࡚ࠊⓎ⌧ࡍࡿ DAZL ࢱࣥࣃࢡ㉁ࡢࣂࣜ࢔ࣥࢺࡢ✀㢮࡟࠾࠸࡚ࡶࠊᛶᕪࡀㄆࡵࡽ
ࢀࡓࠋ
ㄽᩥⓎ⾲࣭Ꮫ఍Ⓨ⾲➼
1. Ogata, Y., Nishikata, M., Kitada, K., Mizushima, S.,
Jogahara, T., Kuroiwa, A. (2019) Spiny rat SRY lacks
a long Q-rich domain and is not stable in transgenic
mice. Developmental Dynamics. 248:784-794.
2. Washio, K., Mizushima, S., Jogahara, T., Kuroiwa,
A. (2019) Regulation of the Sox3 gene in XO/XO
mammal without Sry, the Amami spiny rat,
Tokudaia osimensis. Cytogenetics and Genome
Research. 159:143-150.
3. Matsuzaki, M., Mizushima, S., Dohra, H., Sasanami,
T. (2020) Expression of transferrin and albumin in
the sperm-storage tubules of Japanese quail andtheir possible involvement in long-term sperm
storage. Journal of Poultry Science. 57:88-96.
4. ᇛࣨཎ㈗㏻㸪୰ᐙ㞞㝯㸪ụᮧⱱ㸪㉺ᮏ▱኱㸪ᆏᮏಙ௓㸪ᶫᮏ㷹☻㸪୕㇂໷㸪㯮ᒾ㯞㔛㸪ᒣ⏣ᩥ㞝㸬(2020) ࢺࢡࣀࢩ࣐ࢺࢤࢿࢬ࣑ (Tokudaia
tokunoshimensis) ࡢ⏕ᜥグ㘓࡜ 2005 ᖺࠥ2016 ᖺࡢศᕸ㸬့ங㢮⛉Ꮫ㸬60:105-116.
5. Mizushima S, Sasanami T, Ono T, Kuroiwa A. The
role of inositol-trisphosphate receptors during egg
activation in Japanese quail. The 2nd International
conference on Tropical Animal Science andProduction 2019. July 9-12, 2019. Suranaree
University of Technology, Thailand.
6. 㯮ᒾ㯞㔛㸸Y ᰁⰍయࢆࡶࡓ࡞࠸့ங㢮✀ࡢᛶᰁⰍయ࡜ᛶỴᐃᶵᵓࡢ㐍໬㸦ᣍᚅㅮ₇㸧㸪㑇ఏ◊◊✲఍ࠕ᭷ᛶ⏕Ṫ࡟࠿࠿ࢃࡿᰁⰍయ࣭ࢡ࣐ࣟࢳ
࣭ࣥ᰾ືែ࡟㛵ࡍࡿ◊✲఍ࠖ㸪2019 ᖺ 6 ᭶ 5 ᪥㸪ᅜ❧㑇ఏᏛ◊✲ᡤ㸦୕ᓥᕷ㸧㸬
7. Ỉᓥ⚽ᡂ㸸࢘ࢬࣛࡢᛶᰁⰍయ㑇ఏᏊࣀࢵࢡ࢔࢘
ࢺᢏ⾡ࡢ㛤Ⓨ㸦࣏ࢫࢱ࣮Ⓨ⾲㸧㸪㑇ఏ◊◊✲఍ࠕ᭷ᛶ⏕Ṫ࡟࠿࠿ࢃࡿᰁⰍయ࣭ࢡ࣐ࣟࢳ࣭ࣥ᰾
ືែ࡟㛵ࡍࡿ◊✲఍ࠖ㸪2019 ᖺ 6 ᭶ 6 ᪥㸪ᅜ❧㑇ఏᏛ◊✲ᡤ㸦୕ᓥᕷ㸧㸬
8. ᕤ⸨൉㤿㸸ᛶᰁⰍయ࡟≉␗࡞㐍໬ࢆ㐙ࡆࡓࢺࢤࢿࢬ࣑ᒓࡢ X ᰁⰍయ୙άᛶ໬ᶵᵓ㸦࣏ࢫࢱ࣮Ⓨ⾲㸧㸪㑇ఏ◊◊✲఍ࠕ᭷ᛶ⏕Ṫ࡟࠿࠿ࢃࡿᰁⰍ
య࣭ࢡ࣐ࣟࢳ࣭ࣥ᰾ືែ࡟㛵ࡍࡿ◊✲఍ࠖ㸪2019
ᖺ 6 ᭶ 6 ᪥㸪ᅜ❧㑇ఏᏛ◊✲ᡤ㸦୕ᓥᕷ㸧㸬
9. 㯮ᒾ㯞㔛㸸Y ᰁⰍయࡢᙺ๭࡜㐠࿨−Y ࢆࡶࡓ࡞࠸့ங㢮ࡢᛶỴᐃ㸦ᣍᚅㅮ₇㸧㸪➨ 112 ᅇ᪥ᮏ⦾Ṫ⏕≀Ꮫ఍ᕷẸබ㛤ㅮᗙࠕᛶ࡟࠾ࡅࡿ࢜ࢫ࡜
࣓ࢫࡢᙺ๭࡟㛵ࡍࡿ᪂ᒎ㛤ࠖ㸪2019 ᖺ 9 ᭶ 2 ᪥㸪໭ᾏ㐨኱Ꮫ㸦ᮐᖠᕷ㸧㸬10. ➲ᾉ▱ᏹ, ᯇᓮⱆ⾰, Ỉᓥ⚽ᡂ㸸࢘ࢬࣛ⢭Ꮚࡢࢲ࢖ࢽࣥ ATPase άᛶ, ᪥ᮏᐙ⚺Ꮫ఍ 2019 ᖺᗘ⛅Ꮨ኱఍, 2019 ᖺ 9 ᭶ 17 ᪥, ᒾᡭ኱Ꮫ㸦┒ᒸᕷ㸧㸬
11. 㯮ᒾ㯞㔛㸪ዟ㔝ᮍ᮶㸪ఀ⸨Ṋᙪ㸪ᑎᑿ⨾✑㸪ᑠᕝ‪ஓ㸪㧗⏣ಟ἞㸪Ỉᓥ⚽ᡂ㸸ࢺࢤࢿࢬ࣑
ᒓ࡟࠾ࡅࡿ SRY 㑇ఏᏊ࡟౫Ꮡࡋ࡞࠸ᛶỴᐃࡢศᏊ࣓࢝ࢽࢬ࣒㸦࣏ࢫࢱ࣮Ⓨ⾲㸧㸪➨ 42 ᅇ᪥ᮏศᏊ⏕≀Ꮫ఍ᖺ఍㸪2019 ᖺ 12 ᭶ 3 ᪥㸪࣐࣓ࣜࣥࢵࢭ⚟ᒸ㸦⚟ᒸᕷ㸧㸬
12. Ỉᓥ⚽ᡂ㸪బ⸨ᮃ㸪ሯ⏣ග㸪➲ᾉ▱ᏹ㸪ᑠ㔝⌔எ㸪㯮ᒾ㯞㔛㸸࢘ࢬࣛࡢ⏕Ṫ⭢࡟࠾ࡅࡿ⏕Ṫ⣽⬊≉␗ⓗ㑇ఏᏊࡢⓎ⌧ゎᯒ㸦࣏ࢫࢱ࣮Ⓨ⾲㸧㸪➨ 42 ᅇ᪥ᮏศᏊ⏕≀Ꮫ఍ᖺ఍㸪2019 ᖺ
12 ᭶ 3 ᪥㸪࣐࣓ࣜࣥࢵࢭ⚟ᒸ㸦⚟ᒸᕷ㸧㸬
13. ᐑᮏ῟ኴ㑻㸪ዟ㔝ᮍ᮶㸪ఀ⸨Ṋᙪ㸪Ỉᓥ⚽ᡂ㸪㯮ᒾ㯞㔛㸸ࢽ࣍ࣥ࢘ࢬࣛ࡟࠾ࡅࡿᛶศ໬㛵㐃㑇ఏᏊ࠾ࡼࡧ᪂つᛶỴᐃೃ⿵㑇ఏᏊࡢゎᯒ㸦࣏ࢫࢱ࣮Ⓨ⾲㸧㸪➨ 42 ᅇ᪥ᮏศᏊ⏕≀Ꮫ఍ᖺ఍㸪2019 ᖺ 12 ᭶ 3 ᪥㸪࣐࣓ࣜࣥࢵࢭ⚟ᒸ㸦⚟ᒸᕷ㸧㸬
14. 㯮ᒾ㯞㔛㸪ዟ㔝ᮍ᮶㸪ఀ⸨Ṋᙪ㸪ᑎᑿ⨾✑㸪ᑠᕝ‪ஓ㸪㧗⏣ಟ἞㸪Ỉᓥ⚽ᡂ㸸ࢺࢤࢿࢬ࣑
ᒓ࡟࠾ࡅࡿ SRY 㑇ఏᏊ࡟౫Ꮡࡋ࡞࠸ᛶỴᐃࡢศᏊ࣓࢝ࢽࢬ࣒㸦ᣍᚅㅮ₇㸧㸪➨ 42 ᅇ᪥ᮏศᏊ⏕≀Ꮫ఍ᖺ఍㸪࣮࣡ࢡࢩࣙࢵࣉࠕᛶࡢ㐃⥆ᛶ㸦ᛶࢫ࣌ࢡࢺ࣒ࣛ㸧ࢆࡶࡓࡽࡍ࢚ࣆࢤࣀ࣒࣭
௦ㅰ࣭ᰁⰍయࠖ
㸪2019 ᖺ 12 ᭶ 5 ᪥㸪࣐࣓ࣜࣥࢵࢭ⚟ᒸ㸦⚟ᒸᕷ㸧㸬
15. 㯮ᒾ㯞㔛㸸ᛶࢆỴࡵࡿ㑇ఏᏊ㸦ᣍᚅㅮ₇㸧㸪᪂Ꮫ⾡㡿ᇦ◊✲ࠕᛶࢫ࣌ࢡࢺ࣒ࣛࠖ୺ദ㧗ᰯ⏕ྥࡅබ㛤ㅮᗙࠕᛶࡢ୙ᛮ㆟−ዪ࡜⏨−ࠖ㸪2019ᖺ 12 ᭶ 14 ᪥㸪ឡ▱┴❧ส㇂㧗➼Ꮫᰯ㸦ส㇂ᕷ㸧
16. Ỉᓥ⚽ᡂ, ሯ⏣ග, ➲ᾉ▱ᏹ, ᑠ㔝⌔எ, 㯮ᒾ㯞㔛㸸㞝࢘ࢬࣛࡢ⏕Ṫ⭢࡟࠾ࡅࡿ DAZL ࡢⓎ⌧ゎᯒ, ᪥ᮏᐙ⚺Ꮫ఍ 2020 ᖺᗘ᫓Ꮨ኱఍,2020 ᖺ 3 ᭶ 28 ᪥, ி㒔኱Ꮫ㸦ி㒔ᕷ㸧㒊㛛 ⏕ṪⓎ⏕⏕≀Ꮫ
Ꮫศ㔝
⏕≀⛉Ꮫ㒊
ᒣୗ ṇව⬨᳝ື≀࡟࠾ࡅࡿ⏕Ṫ⣽⬊ᙧᡂࡢไᚚᶵᵓ

− 16 −

᭷ᛶ⏕ṪࢆႠࡴ⏕≀࡟࡜ࡗ࡚⏕Ṫ⣽⬊ (༸࡜⢭Ꮚ) ࢆసࡾ,ࡑࢀࡽࢆཷ⢭ࡉࡏࡿࡇ࡜ࡣ,ಶయࡢᣢࡘ㝈ࡽࢀࡓᑑ࿨ࢆ㉺࠼࡚✀ࢆᏑ⥆ࡉࡏࡿࡓࡵ࡟
ᚲ㡲ࡢ㐣⛬࡛࠶ࡿࠋ⏕Ṫ⣽⬊ࡀ࡝ࡢᵝ࡞ไᚚࡢࡶ
࡜࡛ᙧᡂࡉࢀ,ཷ⢭ྍ⬟࡟࡞ࡿ࠿ࢆゎ᫂ࡍࡿࡇ࡜
ࡣ,⏕࿨⛉Ꮫ࡟ㄢࡏࡽࢀࡓᇶᮏ࿨㢟ࡢ୍ࡘ࡛,ࡑࡢᛂ⏝ࡣேᕤཷ⢭,㑊ዷ,᭷⏝⏕≀✀ࡢసฟ࡞࡝,ᡃࠎࡢ⏕ά࡟῝ࡃ㛵ಀࡍࡿ✀ࠎࡢ⏕Ṫ᧯స࡟┤⤖ࡍࡿࠋ⢭Ꮚࡣ㞝ᛶ⏕Ṫ⣽⬊ࡢቑṪ࡜ศ໬ࢆไᚚࡍࡿ
ᵝࠎ࡞ศᏊࡀᶵ⬟ࡍࡿࡇ࡜࡛ᙧᡂࡉࢀࡿࡀ,ࡑࡢศᏊᐇయࡸస⏝ᶵᗎࡣ୙᫂ࡢⅬࡀከ࠸ࠋ⢭ᏊᙧᡂࢆไᚚࡍࡿศᏊ⣽⬊ᶵᵓࡢゎᯒ࡟ࡣ⢭Ꮚᙧᡂࢆヨ㦂⟶ෆ࡛෌⌧ࡍࡿᐇ㦂⣔ࡀ᭷⏝࡛࠶ࡿࠋ㏆ᖺ,ჾᐁᇵ㣴࡟ࡼࡗ࡚࣐࢘ࢫࡢ඲⢭Ꮚᙧᡂ㐣⛬ࢆ෌⌧ࡍࡿࡇ࡜ࡀྍ⬟࡜࡞ࡗࡓࡀ,ศᩓࡋࡓ⣽⬊ࢆ⏝࠸ࡓᇵ㣴⣔࡛ࡣᡂຌࡋ࡚࠸࡞࠸ࠋ୍᪉,ᑠᆺ㨶㢮࡛࠶ࡿࢮࣈࣛࣇ࢕ࢵࢩ࡛ࣗࡣศᩓ⣽⬊ᇵ㣴⣔࡛඲⢭Ꮚᙧᡂ㐣⛬ࢆ෌⌧࡛ࡁ࡚࠸ࡿࠋྠࡌࡃᑠᆺ㨶㢮ࡢ࣓ࢲ࡛࢝ࡣ,ࡇࢀࡲ࡛ศᩓ⣽⬊ᇵ㣴⣔࡛⢭ẕ⣽⬊࠿ࡽᶵ⬟ⓗ⢭Ꮚࢆస〇࡛ࡁ࡚࠸ࡿࡀ,⢭ཎ⣽⬊࠿ࡽࡢస〇࡟ࡣᡂຌࡋ࡚࠸࡞࠸ࠋ࣓ࢲ࢝࡜ࢮࣈ
ࣛࣇ࢕ࢵࢩࣗࡣ✀㛫ࡢ㢮ఝᛶ࡜ᕪ␗ࢆㄪ࡭ࡿࡢ࡟
᭷⏝࡛,୧✀ࢆẚ㍑ࡍࡿࡇ࡜࡛⢭Ꮚᙧᡂࢆㄪ⠇ࡍࡿᶵᵓࡢࡼࡾⰋ࠸⌮ゎ࡟ࡘ࡞ࡀࡿ࡜ᮇᚅࡉࢀࡿࠋ
ࡑࡇ࡛,࣓ࢲ࡛࢝⢭ཎ⣽⬊࠿ࡽ⢭Ꮚࡲ࡛ࡢ඲⢭Ꮚᙧᡂ㐣⛬ࢆヨ㦂⟶ෆ࡛෌⌧࡛ࡁࡿศᩓ⣽⬊ᇵ㣴⣔ࢆ☜❧ࡋ,ࡇࡢ⣔ࢆ⏝࠸࡚⢭Ꮚᙧᡂࢆไᚚࡍࡿศ
Ꮚ⣽⬊ᶵᵓ࡟㏕ࡿࡇ࡜࡟ࡋࡓࠋ
ࡲࡎ,ᪧ᮶ࡢᇵ㣴ᾮ㸦S medium㸧࡟࣍ࣝࣔࣥ➼ࢆຍ࠼ࡓ᪂ࡋ࠸ᇵ㣴ᾮ㸦MS medium㸧ࢆ㛤Ⓨࡋࡓࠋࡉࡽ࡟,ࣇ࢕࣮ࢲ࣮⣽⬊࡜ࡋ࡚࣓ࢲ࢝⢭ᕢ⏤᮶ࡢయ ⣽ ⬊ ᰴ ࡛ ࠶ ࡿ Mtp1 ࢆ ⏝ ࠸ ࡓ ᇵ 㣴 㸦 MS
medium/Mtp1㸧ࡶ᳨ウࡋࡓࠋ࣓ࢲ࢝⢭ᕢ⣽⬊࠿ࡽࢭࣝࢯ࣮ࢱ࣮࡛ᚓࡓ⢭ཎ⣽⬊ࢆከࡃྵࡴ⏬ศࢆୖグ
3 ᮲௳࡛ᇵ㣴ࡋࡓ⤖ᯝ,S medium㸪MS medium㸪MS
medium/Mtp1 ࡢ㡰࡛,DNA 」〇ࡀஹ㐍ࡍࡿࡇ࡜ࡀ
ࢃ࠿ࡗࡓࠋࡲࡓ,MS medium ࡜ MS medium/Mtp1 ࡛ࡣ⢭ཎ⣽⬊࠿ࡽ⢭Ꮚࡀᙧᡂࡉࢀࡿࡇ࡜ࢆ☜ㄆࡋࡓࠋ
Mtp1 ࡣ」ᩘ✀ࡢ⣽⬊ࢆྵࡴ㞟ᅋ࡜ண᝿ࡉࢀࡓࡓ
ࡵ,ࢭࣝࢺࣜ⣽⬊,ࣛ࢖ࢹ࢕ࢵࣄ⣽⬊,⏕Ṫ⣽⬊ࡢࡑࢀࡒࢀ࡟≉␗ⓗ࡞࣐࣮࣮࢝㑇ఏᏊࡢⓎ⌧ࢆㄪ࡭ࡓࠋ
ࡑࡢ⤖ᯝ,Mtp1 ࡟ࡣࢭࣝࢺࣜ⣽⬊࡜ࣛ࢖ࢹ࢕ࢵࣄ
⣽⬊ࡀΰᅾࡋ࡚࠸ࡿ࡜⤖ㄽࡉࢀࡓࠋ⢭ཎ⣽⬊ࢆ
Mtp1 ࡜ඹᇵ㣴ࡍࡿ࡜⢭Ꮚᙧᡂࡀಁ㐍ࡉࢀࡿ࡜࠸
࠺⤖ᯝࡣ,⢭Ꮚᙧᡂ࡟ᚲ㡲ࡢࢭࣝࢺࣜ⣽⬊࡜ࣛ࢖ࢹ࢕ࢵࣄ⣽⬊ࡀ Mtp1 ࡟ྵࡲࢀ࡚࠸ࡿࡓࡵ࡜⤖ㄽࡉࢀࡓࠋ⢭Ꮚᙧᡂไᚚ࡟ࡣࢧ࢖ࢺ࢝࢖ࣥࡀ㛵ࢃࡿ࡜ண᝿
ࡉࢀࡿࠋࢧ࢖ࢺ࢝࢖ࣥࡢ 1 ✀࡛࠶ࡿⓑ⾑⑓ᢚไᅉᏊ㸦Lif㸧ࡢ࣓ࢲ࢝⢭ᕢ࡟࠾ࡅࡿᶵ⬟ࢆ㸪᪂つ࡟☜❧ࡋࡓᇵ㣴⣔ࢆ⏝࠸࡚ㄪ࡭ࡓࠋࡑࡢ⤖ᯝ,ࣂ࢟ࣗࣟ࢘࢖ࣝࢫ⏘⏕⤌᥮࠼࣓ࢲ࢝ Lif ࢱࣥࣃࢡ㉁ࡢᇵᆅ
࡬ࡢῧຍࡸ Lif 㐣๫Ⓨ⌧ Mtp1 ⣽⬊࡜ࡢඹᇵ㣴ࡀ,⢭ཎ⣽⬊ࡢቑṪࢆಁ㐍ࡍࡿࡇ࡜ࢆぢฟࡋࡓࠋࡲ
ࡓ,Lif ࡢ mRNA ࡜ࢱࣥࣃࢡ㉁ࡀ⢭ཎ⣽⬊࡜ࡑࡢ࿘ᅖࡢࢭࣝࢺࣜ⣽⬊࡛Ⓨ⌧ࡋ࡚࠸ࡿࡇ࡜ࡶ☜ㄆࡋࡓࠋࡇࢀࡽࡢ⤖ᯝࡣ Lif ࡀ࣓ࢲ࢝⢭ཎ⣽⬊ࡢቑṪࢆไᚚࡍࡿᶵ⬟ࢆᣢࡘࡇ࡜ࢆ♧၀ࡍࡿࠋㄽᩥⓎ⾲Satoh, R., Bando, H., Sakai, N., Kotani, T., andYamashita, M. (2019) Function of leukaemia inhibitory
factor in spermatogenesis of a teleost fish, the medaka
Oryzias latipes. Zygote 27 (6): 423-431.
Hagiwara, A., Ogiwara, K., Sugama, N., Yamashita, M.
and Takahashi, T. (2020) Inhibition of medaka ovulation
by gap junction blockers due to its disrupting effect on thetranscriptional process of LH-induced Mmp15 expression.
General and Comparative Endocrinology 288: 113373.
⏕≀⛉Ꮫ㒊㒊㛛 ⏕ṪⓎ⏕⏕≀ᏛᏛศ㔝Ⲷཎ ඞ┈⬨᳝ື≀ࡢ⏕Ṫჾᐁࡢᶵ⬟࡟㛵ࡍࡿ◊✲㸦◊✲┠ⓗ㸧⬨᳝ື≀ࡢ⏕Ṫάືࡣ㸪どᗋୗ㒊㸦⬻㸧㸫⬻ୗᆶయ㸫⏕Ṫ⭢࠿ࡽ࡞ࡿ⏕ṪෆศἪ⣔࡟ࡼࡾㄪ⠇ࡉࢀ㸪༸ᕢ࡛ࡘࡃࡽࢀࡿ༸࡜⢭ᕢ࡛ࡘࡃࡽࢀ
ࡿ⢭Ꮚࡢྜయ㸦ཷ⢭㸧࡟ࡼࡾ᪂ࡋ࠸ಶయࡀ࡛ࡁࡿࠋ
ᙜ◊✲ᐊ࡛ࡣ㸪༸ᕢ㸪⢭ᕢ➼࡟࠾ࡅࡿᵝࠎ࡞⌧㇟ࢆศᏊ࡛ࣞ࣋ࣝゎᯒࡋࠊࡑࡢ࣓࢝ࢽࢬ࣒ࢆゎ᫂ࡍࡿࡇ࡜ࢆ┠ⓗ࡟◊✲ࢆ㐍ࡵ࡚࠸ࡿࠋ⌧ᅾࡣࠊ⬨᳝ື≀ࡢ༸ᕢᶵ⬟㸦≉࡟༸Ꮚᙧᡂࡸ᤼༸㸧࡟㛵㐃ࡍࡿᮍゎ᫂࡞ㄢ㢟࡟ྲྀࡾ⤌ࢇ࡛࠸ࡿࠋ
㸦⤒㐣࣭⤖ᯝ㸧ᙜ◊✲ᐊ࡛ࡣ㸪ᐇ㦂ᮦᩱ࡜ࡋ࡚࣓
ࢲ࢝ࡸ࣐࢘ࢫࢆ⏝࠸࡚◊✲ࢆ⾜ࡗ࡚࠸ࡿࠋ࣓ࢲ࢝
ࡣࠊ᤼༸ᐇ⾜࡟ᚲせ୙ྍḞ࡞㓝⣲㸦᤼༸㓝⣲㸧ࡀࡍ࡛࡟ྠᐃࡉࢀ࡚࠾ࡾࠊࡉࡽ࡟⏕యእ࡛᤼༸⌧㇟ࢆほᐹ࡛ࡁࡿᇵ㣴⣔ࡀ฼⏝ྍ⬟࡞ࡇ࡜࠿ࡽࠊ᤼༸
◊✲࡟㐺ࡋࡓᐇ㦂ື≀࡛࠶ࡿࠋ࣓ࢲ࢝ࢆ⏝࠸ࡓ᤼༸㛵㐃◊✲࡜ࡋ࡚௨ୗࡢ 2 ࢸ࣮࣐࡟ࡘ࠸࡚◊✲ࢆ⾜ࡗ࡚࠸ࡿࠋࡲࡓࠊ࣐࢘ࢫࢆ⏝࠸ࡓ◊✲ࢸ࣮࣐࡜ࡋ࡚௨ୗࡢ◊✲ࢆ⾜ࡗ࡚࠸ࡿࠋ
㸦1㸧᤼༸㛵㐃㑇ఏᏊḞᦆ࣓ࢲ࢝ࡢస〇ᙜ◊✲ᐊࡢࡇࢀࡲ࡛ࡢ◊✲࡟ࡼࡾࠊ᤼༸┤๓࡟ᛴ⃭࡟ㄏᑟࡉࢀࡿ MT2-MMP ࡀࠊ᤼༸ࡢ㝿ࠊ㔜せ࡞ᙺ๭ࢆᢸ࠺ࡇ࡜ࡀ᫂ࡽ࠿࡜࡞ࡗ࡚࠸ࡿࠋࡲࡓࠊ
᰾ෆࣉࣟࢤࢫࢳࣥཷᐜయ㸦nPR㸧ࡀ MT2-MMP ࢆྵࡴᵝࠎ࡞᤼༸㛵㐃㑇ఏᏊࡢⓎ⌧ㄏᑟ࡟㛵୚ࡍࡿࡇ࡜ࡶ᫂ࡽ࠿࡜࡞ࡗ࡚࠸ࡿࠋ⌧ᅾࠊCRISPR-Cas9ࢩࢫࢸ࣒ࢆ⏝࠸࡚ࠊMT2-MMP Ḟᦆ࣓ࢲ࢝࡜ nPRḞᦆ࣓ࢲ࢝ࡢసฟࢆ㐍ࡵ࡚࠸ࡿࠋMT2-MMP Ḟᦆ࣓ࢲ࢝࡟ࡘ࠸࡚ࡣࠊࣇ࣮࣒ࣞࢩࣇࢺ࡟ࡼࡾ㏵୰࡛

− 17 −

⤊ጞࢥࢻࣥࡀධࡿኚ␗࣓ࢲ࢝ࡀ 2 ⣔⤫ᚓࡽࢀ࡚࠾
ࡾࠊ1 ⣔⤫࡟ࡘ࠸࡚ࡣ࣓࣍ࣔࢲ࢝ࡢసฟࡲ࡛⤊஢ࡋ࡚࠸ࡿࠋ⌧ᅾࠊ᤼༸ࡢ᭷↓ࢆྵࡵࡓ⾲⌧ᆺࡢゎᯒࢆ㐍ࡵ࡚࠸ࡿࠋࡲࡓࠊࡶ࠺ 1 ⣔⤫࡟ࡘ࠸࡚ࡣࠊ
࣊ࢸ࣓ࣟࢲ࢝ࡢసฟࡲ࡛㐍ࢇ࡛࠾ࡾࠊ௒ᚋ࣓࣍ࣔ
ࢲ࢝ࢆసฟࡍࡿணᐃ࡛࠶ࡿࠋ୍᪉ࠊnPR Ḟᦆ࣓ࢲ࢝࡟ࡘ࠸࡚ࡣࠊ୍㒊࢔࣑ࣀ㓟Ḟᦆࡀ࠾ࡇࡿኚ␗ࡀ
ᑟධࡉࢀࡓኚ␗࣓ࢲ࢝ࡀ 2 ⣔⤫ࠊࣇ࣮࣒ࣞࢩࣇࢺ
࡟ࡼࡾ㏵୰࡛⤊ጞࢥࢻࣥࡀධࡿኚ␗࣓ࢲ࢝ࡀ 1 ⣔⤫ᚓࡽࢀࡓࠋ⌧ᅾࠊࡇࢀࡽࡢ⣔⤫ࡢ࣊ࢸ࣓ࣟࢲ࢝
ࡢసฟࡲ࡛᏶஢ࡋ࡚࠾ࡾࠊ௒ᚋ࣓࣍ࣔࢲ࢝ࡢసฟ
࡬࡜⛣ࡿணᐃ࡛࠶ࡿࠋ
㸦2㸧༸ẕ⣽⬊࡜ℐ⬊⣽⬊ࡢ㐃㛵ᛶ༸ẕ⣽⬊ࡣℐ⬊ෆ࡛ᡂ㛗ࡋࠊཷ⢭ྍ⬟࡞≧ែ࡟࡞ࡿ࡜᤼༸ࡉࢀࡿࠋℐ⬊ࡣ༸ẕ⣽⬊࡜༸ẕ⣽⬊ࢆ
ᅖࡴℐ⬊⣽⬊ᒙ࠿ࡽᡂࡿࡀࠊ့ங㢮ࡢ◊✲࡟࠾࠸࡚ࠊ༸ẕ⣽⬊ࡀℐ⬊⣽⬊ᒙ࡜ࢥ࣑ࣗࢽࢣ̿ࢩࣙࣥ
ࢆྲྀࡾ࡞ࡀࡽࠊ༸ᡂ⇍ࡢไᚚࢆ⾜ࡗ࡚࠸ࡿࡇ࡜ࡀ
ሗ࿌ࡉࢀ࡚࠸ࡿࠋࡑࡇ࡛ࠊ၏୍ࠊ⬨᳝ື≀࡟࠾࠸࡚᤼༸ࡢศᏊᶵᵓࡢヲ⣽ࡀ᫂ࡽ࠿࡜࡞ࡗ࡚࠸ࡿ࣓
ࢲ࢝ࢆ⏝࠸࡚༸ẕ⣽⬊࡜ℐ⬊⣽⬊ᒙࡀ࠾஫࠸࡟ࢥ
࣑ࣗࢽࢣ࣮ࢩࣙࣥࢆྲྀࡗ࡚༸ᡂ⇍ࡸ᤼༸࡞࡝ࡢไ
ᚚࢆ⾜ࡗ࡚࠸ࡿࡢ࠿࡟ࡘ࠸࡚ㄪ࡭ࡓࠋ᤼༸ࡢ࣮࢟
㓝⣲࡛࠶ࡿ MT2-MMP ࢆᣦᶆ࡜ࡋࠊ༸ᕢ࠿ࡽ༢㞳
ࡋࡓℐ⬊ࢆࡑࡢࡲࡲᇵ㣴ࡍࡿሙྜ࡜ℐ⬊ࢆ₽ࡋ࡚༸ẕ⣽⬊ࢆ◚ቯᚋ࡟ᇵ㣴ࡍࡿሙྜ࡛ MT2-MMP
ࡢⓎ⌧࡟ᕪ␗ࡀ࠶ࡿ࠿࡝࠺࠿ㄪ࡭ࡓ࡜ࡇࢁࠊ◚ቯ
ᚋࡢℐ⬊ࢆᇵ㣴ࡋࡓࢣ࣮ࢫ࡛ࡣࠊMT2-MMP ࡢⓎ⌧ㄏᑟࡣࠊ༢㞳ࡋࡓℐ⬊ࢆࡑࡢࡲࡲᇵ㣴ࡍࡿሙྜ࡜ẚ㍑ࡋ࡚᭷ព࡟᪩ࡲࡗࡓࠋࡇࡢ⤖ᯝࡣࠊ༸ẕ⣽⬊࠿ࡽศἪࡉࢀࡿఱࡽ࠿ࡢᅉᏊ࡟ࡼࡾ MT2-MMP
ࡢⓎ⌧ࡀㄪ⠇㸦ᢚไ㸧ࡉࢀ࡚࠸ࡿࡇ࡜ࢆ♧၀ࡋ࡚࠸ࡿࠋ᫖ᖺᗘࡢ㏵୰⤒㐣ࡢሗ࿌࡛ࡣୖグࡢሗ࿌ࢆ⾜ࡗࡓࡀࠊ௒ᖺᗘࡢ㏵୰⤒㐣ࡣ௨ୗࡢ㏻ࡾ࡛࠶ࡿࠋ
့ங㢮ࢆ⏝࠸ࡓ◊✲࠿ࡽࠊGDF9ࠊBMP15 ࡞࡝ࡀ
MT2-MMP ࡢⓎ⌧ไᚚ࡟㛵ࢃࡗ࡚࠸ࡿྍ⬟ᛶࡀ࠶ࡿࡇ࡜ࡀ⪃࠼ࡽࢀࠊᐇ㝿࡟࣓ࢲ࢝᤼༸๓༸ẕ⣽⬊࡟ࡇࢀࡽࡢⓎ⌧ࡀ☜ㄆ࡛ࡁࡓࠋࡑࡇ࡛ࠊ༸ẕ⣽⬊࡛ࡢࢱࣥࣃࢡ㉁Ⓨ⌧ࡸᇵ㣴ᾮ୰࡬ࡢศἪࡢ᭷↓ࢆㄪ࡭ࡿࡓࡵ࡟ GDF9 ࡜ BMP15 ࡢ≉␗ⓗᢠయࡢస〇ࢆヨࡳࡓࠋBMP15 ࡟ࡘ࠸࡚ࡣ≉␗ⓗᢠయࡢస〇࡟ᡂຌࡋࠊ⌧ᅾゎᯒ୰࡛࠶ࡿࠋGDF9 ࡟ࡘ࠸࡚ࡣࠊ
኱⭠⳦࡛ࡢᢠཎస〇ࡀ୙ㄪ࡟⤊ࢃࡾࠊ≉␗ⓗᢠయࡢస〇࡟╔ᡭ࡛ࡁ࡞࠿ࡗࡓࠋࡑࡇ࡛ࠊᕷ㈍ࡢᢠయ
ࢆఱ✀㢮࠿ヨࡋࡓࡀࠊ࣓ࢲ࢝ GDF9 ࢆ≉␗ⓗ࡟ㄆ㆑ࡍࡿᢠయࢆᡭ࡟ධࢀࡿࡇ࡜ࡣ࡛ࡁ࡞࠿ࡗࡓࠋ
㸦3㸧ℐ⬊㑅ᢥᶵᵓࡢゎ့᫂ங㢮ࡢ༸ᕢ࡟ࡣࠊཎጞℐ⬊࡜ࡼࡤࢀࡿℐ⬊ࡀከᩘࢫࢺࢵࢡࡉࢀ࡚࠸ࡿࠋࡇࡢཎጞℐ⬊ࡢ୍㒊㸦ᩘ༑ಶ㹼ⓒಶ⛬ᗘ㸧ࡀఱࡽ࠿ࡢ่⃭࡟ࡼࡾᡂ㛗ࢆ㛤ጞࡋࠊ᭱⤊ⓗ࡟㸯㹼10 ಶ⛬ᗘࡢ༸Ꮚࡀ᤼༸ࡉࢀࡿࠋ

ᡂ㛗ࢆ㛤ጞࡋࡓℐ⬊ࡢ኱㒊ศࡣࠊ㏵୰࡛ᡂ㛗ࢆ೵Ṇࡋࠊ࢔࣏ࢺ࣮ࢩࢫ࡟ࡼࡾṚ⁛ࡍࡿࠋࡇࡢ㐣⛬ࡀ
ℐ⬊㑅ᢥ࡛࠶ࡿࡀࠊ⏕ࡁṧࡿℐ⬊࡜࢔࣏ࢺ࣮ࢩࢫ
࡟ࡼࡾṚ⁛ࡍࡿℐ⬊ࡣ࡝ࡢࡼ࠺࡟㑅ูࡉࢀ࡚࠸ࡿ
ࡢ࠿ࠊࡑࡢศᏊᶵᵓࢆ᫂ࡽ࠿࡟ࡍࡿࡇ࡜ࡀᮏ◊✲ࡢ┠ⓗ࡛࠶ࡿࠋ
100 ಶ๓ᚋࡢ༸Ꮚࢆ᤼༸ࡉࡏࡿࡇ࡜ࡀ࡛ࡁࡿ⸆
๣㸦PMSG/hCG ➼࡛㐣᤼༸ࢆㄏᑟࡍࡿ࡜࣐࢘ࢫࡢ
ሙྜࠊ10-20 ಶ⛬ᗘࡀ᤼༸ࡉࢀࡿ㸧ࢆ⏝࠸࡚᤼༸ࢆㄏᑟࡋࡓ࣐࢘ࢫࡢ༸ᕢ࡜㏻ᖖࡢ㐣᤼༸ࢆㄏᑟࡋ
ࡓ࣐࢘ࢫࡢ༸ᕢࢆ⏝࠸࡚ RNA-seq ゎᯒࢆ⾜ࡗࡓࠋᡂ㛗ᅉᏊࠊࢫࢸࣟ࢖ࢻ࣍ࣝࣔࣥཬࡧࡑࡢཷᐜయࠊ
࢔࣏ࢺ࣮ࢩࢫ࡞࡝࡟㛵㐃ࡍࡿᅉᏊ࡟ࡘ࠸࡚ࠊⓎ⌧㔞࡟ᕪࡢ࠶ࡿ㑇ఏᏊࢆ㑅ูࡋࠊrealtime-PCR ࢆ⾜ࡗࡓࠋࡑࡢ⤖ᯝࠊ」ᩘࡢ᭷ព࡟Ⓨ⌧㔞࡟ᕪࡀ࠶ࡿ
㑇ఏᏊࢆⓎぢࡋࡓࠋ⌧ᅾࡇࢀࡽࡢ㑇ఏᏊ࡟ࡘ࠸࡚ࠊࡉࡽ࡟ヲ⣽࡞ゎᯒࢆ⾜ࡗ࡚࠸ࡿࠋ
ㄽᩥ
1. *Hagiwara A., *#Ogiwara K., Sugama N., Yamashita
M., #Takahashi T (2019). Inhibition of medaka
ovulation by gap junction blockers due to its disrupting
effect on the transcriptional process of LH-induced
Mmp15 expression. Gen. Comp. Endocrinol.
288:113373. doi: 10.1016/j.ygcen.2019.113373.
(*: These two authors are equally contributed
to this work. #: These two are co-corresponding
authors.)
2. Ogiwara K., Takahashi T. (2019) Nuclear
Progestin Receptor Phosphorylation by Cdk9 Is
Required for the Expression of Mmp15, a
Protease Indispensable for Ovulation in Medaka.
Cells. 8(3), pii: E215. doi: 10.3390/cells8030215.
3. Takahashi T., Hagiwara A., Ogiwara K. (2019)
Follicle rupture during ovulation with emphasis
on recent progress in fish models. (review)
Reproduction 157, issue 1, DOI: 10.1530/REP-18-0251.
Ꮫ఍Ⓨ⾲Ⲷཎඞ┈ࠊ㧗ᶫᏕ⾜CDK9 ࡟ࡼࡿ᰾ᆺࣉࣟࢤࢫࢳࣥཷᐜయࡢࣜࣥ㓟໬ࡀ࣓ࢲ࢝᤼༸㓝⣲ MT2-MMP ࡢⓎ⌧ㄏᑟ࡟ᚲせ࡛࠶ࡿ➨ 90 ᅇ᪥ᮏື≀Ꮫ఍኱㜰኱఍ࠊ2019 ᖺ 9 ᭶ 12-14᪥ࠊ኱㜰ᕷ❧኱Ꮫᮡᮏ࢟ࣕࣥࣃࢫ㸦኱㜰ᕷ㸧Ώ㑓ᘺஓࠊ୰₲┤ᕫࠊ➉ᑿ㏱ࠊⲶཎඞ┈࣐࢘ࢫℐ⬊㑅ᢥ࡟࠾ࡅࡿ 17β-estradiol ࡢ㛵୚➨ 90 ᅇ᪥ᮏື≀Ꮫ఍኱㜰኱఍ࠊ2019 ᖺ 9 ᭶ 12-14᪥ࠊ኱㜰ᕷ❧኱Ꮫᮡᮏ࢟ࣕࣥࣃࢫ㸦኱㜰ᕷ㸧Ⲷཎඞ┈ࠊ⾜ಇ⏤ோࠊⴗཎⲁࠊ㧗ᶫᏕ⾜࣓ࢲ࢝᤼༸࡜༸ᡂ⇍ࡢ㛫࡟㐃㛵ᛶࡣ࠶ࡿࡢ࠿ࠊࡑ
ࢀ࡜ࡶ⊂❧ࡋ࡚㐍⾜ࡋ࡚࠸ࡿࡢ࠿㸽− 18 −

➨ 44 ᅇ᪥ᮏẚ㍑ෆศἪᏛ఍኱఍ࠊ
2019 ᖺ 11 ᭶ 8-10᪥ࠊᇸ⋢኱Ꮫ㸦ࡉ࠸ࡓࡲᕷ㸧⾜ಇ⏤ோࠊⴗཎⲁࠊ㧗ᶫᏕ⾜ࠊⲶཎඞ┈࣓ࢲ࢝༸ẕ⣽⬊⏤᮶ࡢᅉᏊ࡟ࡼࡿ᤼༸㓝⣲
MT2-MMP ࡢⓎ⌧ㄏᑟไᚚ➨ 44 ᅇ᪥ᮏẚ㍑ෆศἪᏛ఍኱఍ࠊ
2019 ᖺ 11 ᭶ 8-10᪥ࠊᇸ⋢኱Ꮫ㸦ࡉ࠸ࡓࡲᕷ㸧ࡘ࠸࡚ࡣ㏆ഐࡢ㑇ఏᏊࡢⓎ⌧ࡶపୗࡋࡓࠋࡇࢀࡽ
ࡢࡇ࡜࠿ࡽࠊᡃࠎࡀྠᐃࡋࡓ㡿ᇦࡢከࡃࡀᐇ㝿࡟dual promoter-enhancer ࡜ࡋ࡚ᶵ⬟ࡋ࡚࠸ࡿࡶࡢ࡜
⪃࠼ࡽࢀࡿࠋ௨ୖࡢᡂᯝࡣࠊ⢭Ꮚᙧᡂ࡟࠾ࡅࡿ≉␗ⓗ࡞㑇ఏᏊࡢ㌿෗άᛶ໬ࡢከࡃ࡟ከᶵ⬟ᛶࢤࣀ࣒ࡀᶵ⬟ࡍࡿ࡜࠸࠺᪂ࡋ࠸▱ぢࢆ୚࠼ࡿࡶࡢ࡛࠶
ࡾࠊ⢭Ꮚᙧᡂ࣓࢝ࢽࢬ࣒ࡢ඲ᐜゎ᫂࡟ྥࡅ࡚኱ࡁ
࡞㐍ᒎࢆࡶࡓࡽࡍࡶࡢ࡛࠶ࡿࠋ

㒊㛛 ⏕ṪⓎ⏕⏕≀Ꮫศ㔝⏕≀⛉Ꮫ㒊ᮌᮧ ᩔ

㸺ㄽᩥⓎ⾲㸼
1. Takahashi N., Kimura A.P., Otsuka K., Ohmura
K., Naito S., Yoshida M., and Ieko M. (2019)㸺◊✲ㄢ㢟ྡ㸼Dreh, a long noncoding RNA repressed by့ங㢮ࡢ⏕Ṫ࡟㛵ࢃࡿࢤࣀ࣒ᶵ⬟࡟㛵ࡍࡿ◊✲
metformin, regulates glucose transport in C2C12
skeletal muscle cells. Life Sci. 236: 116906.
㸺฼⏝≧ἣ࣭ᡂᯝ㸼㸺Ꮫ఍Ⓨ⾲㸼
ᙜ◊✲ᐊ࡛ࡣࠊ့ங㢮ࡢ⏕Ṫ࡟࠾ࡅࡿࢤࣀ࣒ᶵ
1. Bandara A.M.T.K., Matsubara S., Shiraishi A.,⬟ࢆゎ᫂ࡍࡿࡇ࡜ࢆ┠ⓗ࡜ࡋ࡚ࠊ⏕Ṫჾᐁ࡟࠾ࡅ
Satake H., and Kimura A.P. ࠕ Genome-wideࡿ㑇ఏᏊⓎ⌧ㄪ⠇ᶵᵓࢆㄪᰝࡋ࡚࠸ࡿࠋලయⓗ࡟
identification of dual promoter-enhancers in mouseࡣ༸ᕢࠊ⢭ᕢࠊ⫾┙࡛Ⓨ⌧ࡍࡿࡉࡲࡊࡲ࡞㑇ఏᏊ
testisࠖ➨ 44 ᅇ᪥ᮏẚ㍑ෆศἪᏛ఍኱఍㸦ᇸ⋢ࡀ࡝ࡢࡼ࠺࡞࣓࢝ࢽࢬ࣒࡛ไᚚࡉࢀ࡚࠸ࡿࡢ࠿ࢆ
኱Ꮫࠊ2019 ᖺ 11 ᭶ 9 ᪥㸧ศᏊ࡛ࣞ࣋ࣝㄪ࡭࡚࠾ࡾࠊᚲせ࡟ᛂࡌ࡚㑇ఏᏊࡢ
2.
኱ሯᾏࠊబ⸨ඃ⾰ࠊᮌᮧᩔࠕ࣐࢘ࢫ
Prss/ Tesspᶵ⬟ゎᯒࡶ⾜ࡗ࡚࠸ࡿࠋ௒ᖺᗘࡣࠊ⢭Ꮚᙧᡂ࡟࠾
㑇ఏᏊᗙ࠿ࡽ㌿෗ࡉࢀࡿ᪂つ㛗㙐㠀ࢥ࣮ࢻࡅࡿከᶵ⬟ᛶࢤࣀ࣒࡟ࡘ࠸࡚ࡢ᪂ࡋ࠸▱ぢࢆᚓࡓࠋRNA ࡢⓎ⌧࣭ᶵ⬟ゎᯒࠖ➨ 44 ᅇ᪥ᮏẚ㍑ෆศ
㌿෗ࢆไᚚࡍࡿᅉᏊ࡟ࡣࡉࡲࡊࡲ࡞ࡶࡢࡀ▱ࡽἪᏛ఍኱఍㸦ᇸ⋢኱Ꮫࠊ2019 ᖺ 11 ᭶ 9 ᪥㸧ࢀ࡚࠸ࡿࡀࠊᡃࠎࡣ࣐࢘ࢫ⢭ẕ⣽⬊≉␗ⓗ࡟Ⓨ⌧
ࡍࡿ Tcam1 㑇ఏᏊᗙ࡟࠾࠸࡚ࠊࣉ࣮ࣟࣔࢱ࣮࡜࢚
㒊㛛 ⏕ṪⓎ⏕⏕≀Ꮫ
Ꮫศ㔝
⏕≀⛉Ꮫ㒊
ࣥࣁࣥࢧ࣮ࡢ୧᪉ࡢάᛶࢆేࡏᣢࡘከᶵ⬟ᛶࢤࣀᑠ㇂ ཭ஓ
࣒ࠕdual promoter-enhancerࠖࡀᶵ⬟ࡍࡿࡇ࡜ࢆⓎぢࡋࡓ㸦Kurihara et al., J. Mol. Biol. 426:3069-3093,
ከࡃࡢ⏕࿨⌧㇟ࡣࠊ㑇ఏᏊ⏘≀ࡀ㐺ษ࡞᫬ᮇ࡟
2014㸧ࠋࡇࡢᡂᯝ࠿ࡽࠊᡃࠎࡣ dual promoter-enhancer㐺ษ࡞㒊఩࡛ᶵ⬟ࡍࡿࡇ࡜࡛㐍⾜ࡍࡿࠋ㑇ఏᏊ⏘ࡀ⢭Ꮚᙧᡂ࡛ࡼࡾከࡃࡢ㑇ఏᏊࡢ㌿෗άᛶ໬࡟ᶵ
≀ࡀᶵ⬟ࡍࡿ᫬ᮇ࡜㒊఩ࡣࠊ㌿෗࣭⩻ヂ࣭ࢱࣥࣃ⬟ࡍࡿྍ⬟ᛶࡀ࠶ࡿ࡜⪃࠼ࠊࡑࡢ᳨ドࢆ⾜ࡗࡓࠋ
ࢡ㉁ಟ㣭ࡢࡑࢀࡒࢀࡢ࡛ࣞ࣋ࣝไᚚࡉࢀࡿࠋ㌿෗ලయⓗ࡟ࡣࠊ࣐࢘ࢫ⢭ᕢࡼࡾ⢭ཎ⣽⬊࡜୍ḟ⢭ẕࣞ࣋ࣝࡢไᚚᶵᵓ࡜ẚ㍑ࡋࠊ⩻ヂ࡛ࣞ࣋ࣝࡢไᚚ⣽ ⬊ ࢆ ༢ 㞳 ࡋ ࡚ RNA-sequencing ゎ ᯒ ࡜ᶵᵓࡣ୙᫂࡞Ⅼࡀከ࠸ࠋ༸ẕ⣽⬊ࡣᡂ㛗ࡍࡿ㐣⛬
ChIP-sequencing ゎᯒࢆ⾜࠸ࠊⓎ⌧ࡍࡿ㑇ఏᏊࡢࣉ࡛ 1 ୓✀㢮ࢆ㉸࠼ࡿ mRNA ࢆ㌿෗ࡍࡿࠋࡇࢀࡽࡢ
࣮ࣟࣔࢱ࣮㡿ᇦ࡟Ꮡᅾࡍࡿࣄࢫࢺࣥ H3K4 ࣔࣀ࣓࡞࠿࡛༓✀㢮௨ୖࡢ mRNA ࡣࠊ⩻ヂࢆᢚไࡉࢀࢱ
ࢳࣝ໬ࣆ࣮ࢡࢆ᥈ࡋࡓࠋࡑࡢ⤖ᯝࠊከᩘࡢ㡿ᇦࢆ
ࣥࣃࢡ㉁ࢆྜᡂࡋ࡞࠸≧ែ࡛༸⣽⬊㉁࡟⵳✚ࡉࢀࠊdual promoter-enhancer ೃ⿵࡜ࡋ࡚ྠᐃࡍࡿࡇ࡜࡟
ࡑࢀࡒࢀ࡟Ỵࡵࡽࢀࡓ᫬ᮇ࡟⩻ヂࡉࢀࡿࠋࡇࡢ⩻ᡂຌࡋࠊ⯆࿡῝࠸ࡇ࡜࡟ࡑࡢᩘࡣ⢭ཎ⣽⬊ࡀ୍ḟヂไᚚࡣ༸ᙧᡂ࡜⬇Ⓨ⏕ࡢ㐍⾜࡟ᴟࡵ࡚㔜せ࡛࠶⢭ẕ⣽⬊࡟ศ໬ࡍࡿ㐣⛬࡛ᩘಸ࡟ࡶቑຍࡍࡿࡇ࡜
ࡿࠋ⩻ヂไᚚࡢ࣓࢝ࢽࢬ࣒ࡣ୺࡟୧⏕㢮༸ẕ⣽⬊ࡀࢃ࠿ࡗࡓࠋḟ࡟ࠊࡇࡢ᪉ἲ࡛ྠᐃࡉࢀࡿ㡿ᇦࡀࢆ⏝࠸ࡓ⏕໬Ꮫⓗゎᯒ࡟ࡼࡗ࡚◊✲ࡉࢀ࡚ࡁࡓࠋ
ᮏᙜ࡟ࣉ࣮ࣟࣔࢱ࣮άᛶ࡜࢚ࣥࣁࣥࢧ࣮άᛶࡢ୧
⌧ᅾ࡛ࡣࠊmRNA ࡢ㓄ิ࡟ᏑᅾࡍࡿࢩࢫᅉᏊ࡟
᪉ࢆేࡏᣢࡘࡢ࠿᳨ドࡍࡿࡓࡵࠊ࣐࢘ࢫ⢭ẕ⣽⬊RNA ⤖ྜࢱࣥࣃࢡ㉁ࡀ⤖ྜࡋ⩻ヂࢆㄪ⠇ࡍࡿࡇ⏤᮶ࡢ GC-2spd(ts)⣽⬊࡛ࡶྠᵝࡢ⥙⨶ゎᯒࢆ⾜ࡗ࡜ࡀ᫂ࡽ࠿࡜࡞ࡗ࡚ࡁ࡚࠸ࡿࠋ୍᪉ࠊ⩻ヂࢆᢚไ࡚ dual promoter-enhancer ೃ⿵ࢆྠᐃࡋࡓᚋࠊࡑࢀ
ࡉࢀࡓ mRNA ࡣ⢏Ꮚ≧ࡢᵓ㐀ࢆ࡜ࡾᏑᅾࡍࡿ࡜࠸
ࡽࡢάᛶࢆㄪ࡭ࡓࠋ࣏࣮ࣞࢱ࣮ゎᯒࡢ⤖ᯝࠊㄪ࡭࠺௬ㄝࡀ 1966 ᖺ࡟ Spirin ࡟ࡼࡗ࡚ᥦၐࡉࢀ࡚࠸ࡿࠋ
ࡓ 11 ಶࡢ㓄ิࡢ࠺ࡕ 7 ಶࡀࣉ࣮ࣟࣔࢱ࣮࡜࢚ࣥࣁ
ࡋ࠿ࡋࠊࡑࡢᐇែࡣ୙࡛᫂࠶ࡗࡓࠋ
ࣥࢧ࣮ࡢ୧᪉ࡢάᛶࢆ♧ࡋࡓࠋࡉࡽ࡟ࠊ2 ࡘࡢ㓄ᡃࠎࡣ⩻ヂࢆᢚไࡉࢀࡓ Cyclin B1 mRNA ࡀ༸ิ࡟ࡘ࠸࡚ࠊCrispr/Cas9 ࢆ⏝࠸ࡓࢤࣀ࣒⦅㞟ἲ࡟⣽⬊㉁࡛㢛⢏≧ࡢᵓ㐀ࢆ࡜ࡿࡇ࡜ࠊῶᩘศ⿣ࡢ㐍ࡼࡾ GC-2spd(ts)⣽⬊࡛Ḟᦆࡉࡏࡓ࡜ࡇࢁࠊ࠸ࡎࢀ
⾜࡟కࡗ࡚ࡇࡢ㢛⢏ᵓ㐀ࡀᾘኻࡋࠊ⩻ヂࡀάᛶ໬ࡶࡑࡢ┤ୗ࡟࠶ࡿ㑇ఏᏊࡢⓎ⌧ࡀపୗࡋࠊ1 ࡘ࡟− 19 −

ࡍࡿࡇ࡜ࢆ♧ࡋ࡚ࡁࡓࠋࡋ࠿ࡋࠊࡇࡢኚ໬ࡢᬑ㐢ᛶ࡜㢛⢏ᵓ㐀ࢆไᚚࡍࡿᶵᵓࡣ୙࡛᫂࠶ࡗࡓࠋ
Mad2 mRNA ࡣῶᩘศ⿣ࡢ➨୍ศ⿣࡟࠾ࡅࡿᰁⰍ
యศ㓄࡟㔜せ࡞ Mad2 ࢱࣥࣃࢡ㉁ࢆࢥ࣮ࢻࡍࡿࠋ
ᮏ◊✲࡛ᡃࠎࡣࠊ࣐࢘ࢫ༸ẕ⣽⬊࡟࠾࠸࡚ Mad2mRNA ࡀ Cyclin B1 mRNA ࡜ྠᵝ࡟⩻ヂࢆᢚไࡉࢀࠊ㢛⢏≧ࡢᵓ㐀ࢆ࡜ࡿࡇ࡜ࢆ᫂ࡽ࠿࡟ࡋࡓࠋࡉ
ࡽ࡟ࠊMad2 mRNA ࡢ⩻ヂᢚไࡣ Cyclin B1 mRNA࡜ྠᵝ࡟ῶᩘศ⿣ࡢ➨୍ศ⿣๓୰ᮇ㸦ῶᩘศ⿣෌
㛤ᚋ 2ࠥ4 ᫬㛫㸧࡛ゎ㝖ࡉࢀࡿࡇ࡜ࠊࡇࢀࡽ mRNAࡣ RNA ⤖ྜࢱࣥࣃࢡ㉁ Pumilio1 ࡢᶆⓗ mRNA ࡛࠶ࡿࡇ࡜ࢆ᫂ࡽ࠿࡟ࡋࡓࠋࡇࢀࡽࡢ⤖ᯝ࠿ࡽࠊ
Cyclin B1 ࡜ Mad2 mRNA ࡣྠࡌ㢛⢏࡟Ꮡᅾࡍࡿࡇ࡜ࡀண ࡉࢀࡓࠋࡋ࠿ࡋࠊࡇࢀࡽ mRNA ࢆྠ᫬࡟᳨ฟࡋࡓ⤖ᯝࠊMad2 mRNA ࡣ Cyclin B1 mRNA ࡢ㢛⢏࡜␗࡞ࡿ㢛⢏࡟Ꮡᅾࡍࡿࡇ࡜ࡀ♧ࡉࢀࡓࠋ࣐࢘ࢫ༸ẕ⣽⬊࡟࠾ࡅࡿ Pumilio1 ࡢศᕸࢆゎᯒࡋࡓ⤖ᯝࠊࡇࡢࢱࣥࣃࢡ㉁ࡣ⣽⬊㉁࡛จ㞟యࢆᙧᡂࡍࡿࡇ࡜ࠊࡇࡢจ㞟యࡣ Mad2 ࡜ Cyclin B1 ࡢ୧᪉ࡢ RNA 㢛⢏ࢆྲྀࡾᅖࡳᏑᅾࡍࡿࡇ࡜ࡀ᫂ࡽ࠿
࡜࡞ࡗࡓࠋGFP ࡛ᶆ㆑ࡋࡓ Pumilio1 ࡣෆᅾࡢPumilio1 ࡜ྠᵝࡢศᕸࢆ♧ࡋࠊ⣙ 40㸣ࡀ୙ືᛶࡢ
ᛶ㉁ࢆᣢࡘࡇ࡜ࡀ♧ࡉࢀࡓࠋGFP-Pumilio1 ࡢจ㞟యࡣῶᩘศ⿣ࡢ㐍⾜࡟క࠸ᣑᩓࡋࠊࡑࡢ࡯࡜ࢇ࡝
ࡀྍືᛶࡢᛶ㉁࡬࡜ኚ໬ࡋࡓࠋࡉࡽ࡟ࠊRNA ⤖ྜ㡿ᇦࢆḞᦆࡋࡓ Pumilio1 ࡣจ㞟యࢆᏳᐃ໬ࡋࠊ
Mad2 ࡜ Cyclin B1 mRNA ࡢ⩻ヂࢆ㜼ᐖࡋࡓࠋྠᵝ
࡟ࠊᢠ Pumilio1 ᢠయࡢᚤ㔞ὀධ࡟ࡼࡗ࡚ Pumilio1ࡢจ㞟యࡣᏳᐃ໬ࡋࠊῶᩘศ⿣ࡢ㐍⾜ࡀ㜼ᐖࡉࢀࡓࠋ௨ୖࡢ⤖ᯝ࠿ࡽࠊPumilio1 ࡢจ㞟యࡣ Mad2
࡜ Cyclin B1 mRNA ࡢ㢛⢏ᵓ㐀ࢆᏳᐃ໬ࡋࠊ⩻ヂᢚไࡢ⥔ᣢ࡟㔜せ࡛࠶ࡿࡇ࡜ࠊࡇࡢจ㞟యࡢᣑᩓࡣ
⩻ヂᢚไࡢゎ㝖ࢆಁ㐍ࡍࡿࡇ࡜ࡀ᫂ࡽ࠿࡜࡞ࡗࡓࠋⓎ⾲ㄽᩥSatoh R, Bando H, Sakai N, Kotani T, Yamashita M.
(2019) Function of leukemia inhibitory factor in
spermatogenesis of a teleost fish, the medaka Oryzias
latipes. Zygote, 27: 423-431.
Ꮫ఍Ⓨ⾲Ṋ஭ኟᾏ, ᕝᮧ⩧ᖹ, 㧗⏣⿱㈗, ᑠ㇂཭ஓ㸸࣐࢘ࢫ༸ẕ⣽⬊࡟࠾ࡅࡿ Pumilio1 ࡢ┦㌿⛣ࢆ௓ࡋࡓ⩻ヂไᚚᶵᵓ. ➨ 90 ᅇ᪥ᮏື≀Ꮫ఍኱㜰኱఍, 2019
ᖺ 9 ᭶ 14 ᪥, ኱㜰ᕷ❧኱Ꮫᮡᮏ࢟ࣕࣥࣃࢫ㸦኱㜰ᕷ㸧ᑠ㇂཭ஓ㸸Temporal and spatial control of translation
by aggregation of an RNA-binding protein Pumilio1
and its dissolution in oocytes. ➨ 42 ᅇ᪥ᮏศᏊ⏕≀Ꮫ఍ᖺ఍, 2019 ᖺ 12 ᭶ 3 ᪥, ⚟ᒸᅜ㝿఍㆟ሙ㸦⚟ᒸᕷ㸧Ṋ஭ኟᾏ, ᒣᮏ㞝ᗈ, ᑠ㇂཭ஓ㸸࣐࢘ࢫ༸ẕ⣽⬊࡟࠾ࡅࡿ㢛⢏ᙧᡂ࡜ᾘኻࢆ௓ࡋࡓ Emi2 mRNA ࡢ⩻ヂไᚚᶵᵓ㸸RNA ⤖ྜࢱࣥࣃࢡ㉁ࡢ㐪࠸࡟ࡼࡿ⩻ヂ᫬ᮇࡢไᚚ. ➨ 42 ᅇ᪥ᮏศᏊ⏕≀Ꮫ఍ᖺ఍,2019 ᖺ 12 ᭶ 5 ᪥, ⚟ᒸᅜ㝿఍㆟ሙ㸦⚟ᒸᕷ㸧㒊㛛 ከᵝᛶ⏕≀Ꮫศศ㔝⏕≀⛉Ꮫ㒊ᑠட ୍ᘯ㸦ᾏỈ฼⏝㸧
Ⓨ⾲ㄽᩥ
Santiañez, W. J. E. and Kogame, K. (2019) Proposals
to recognize Petalonia tenella comb. nov. and to resurrect
Hapterophycus canaliculatus (Scytosiphonaceae,
Phaeophyceae). Botanica Marina 62: 149-153.
Hoshino, M. and Kogame, K. (2019) Parthenogenesis israre in the reproduction of a sexual field population of
the isogamous brown alga Scytosiphon (Scytosiphonaceae,
Ectocarpales). Journal of Phycology 55: 466-472.
Kawai T., Klochkova, N. G., Kogame, K., Abe, T.,
Galanin, D. and Yotsukura, N. (2019) Marine Flora in
Northern Hokkaido and Southern Sakhalin along theCoast of the Sea of Japan. Rishiri Studies 38: 95-98.
Boo, H.-G. Qiu, Y.‐X., Kim, J.-Y., Ang, P. O. Jr., Bosch,S., De Clerck, O., He, P., Higa, A. Huang, B., Kogame,K., Liu, S.‐L., Nguyen, T. V., Suda, S., Terada, R.,
Miller, K. A., and Boo, S. M. (2019) Contrasting
patterns of genetic structure and phylogeography in themarine agarophytes Gelidiophycus divaricatus and G.
freshwateri (Gelidiales, Rhodophyta) from East Asia.
Journal of Phycology 55: 1319-1334.
Hoshino, M., Croce, M. E., Hanyuda, T. and Kogame,
K. (2020) Species delimitation of Planosiphon gracilis
morphospecies (Scytosiphonaceae, Phaeophyceae)
from Japan and the description of Pl. nakamurae sp.
nov. Phycologia 59: 116-126.
Ꮫ఍Ⓨ⾲
Hoshino, M. and Kogame, K.: Insights into the origin ofparthenogenetic populations in the brown alga
Scytosiphon lomentaria (Scytosiphonaceae, Ectocarpales).
7th European Phycological Congress, 25-30 August 2019,
Zagreb, Croatia.
ᫍ㔝㞞࿴㸪⊦㔝༓ᑜ㸪໭ᒣኴᶞ㸪ᑠட୍ᘯ㸸⛥⏘⣚⸴ࢼ࢞࢜ࣂࢿSchimmelmannia plumosaࡢศ㢮Ꮫⓗ෌᳨ウ㸪᪥ᮏ⸴㢮Ꮫ఍➨44ᅇ኱఍㸪2020ᖺ3᭶27㸪
28᪥㸪㮵ඣᓥ኱Ꮫ㸦㮵ඣᓥᕷ㸧㛵ᮏ⍠⳯㸪ᑠட୍ᘯ㸸COIࣂ࣮ࢥ࣮ࢹ࢕ࣥࢢ࡟ࡼࡿ
ᚤᑠ〓⸴ࡢከᵝᛶ㸪᪥ᮏ⸴㢮Ꮫ఍➨44ᅇ኱఍㸪2020
ᖺ3᭶27㸪28᪥㸪㮵ඣᓥ኱Ꮫ㸦㮵ඣᓥᕷ㸧ᒣཱྀᬕ௦㸪㕥ᮌ㔜຾㸪ᕝ஭ᾈྐ㸪⩚⏕⏣ᓅ᫛㸪⛅⏣᫴࿃㸪ᑠட୍ᘯ㸪ᒣཱྀឡᯝ㸪Ἑᆅṇఙ㸸NBRP− 20 −⸴㢮 ➨4ᮇ2019ᖺᗘࡢάື⤂௓㸪᪥ᮏ⸴㢮Ꮫ఍➨44ᅇ኱఍㸪2020ᖺ3᭶27㸪28᪥㸪㮵ඣᓥ኱Ꮫ㸦㮵ඣᓥᕷ㸧㒊㛛 ከᵝᛶ⏕≀Ꮫศศ㔝⏕≀⛉Ꮫ㒊᯳ཎ ᏹ㸦ᾏỈ฼⏝㸧ㄽᩥHasegawa, N. and Kajihara, H. (2019) A redescriptionof Syncarpa composita (Ascidiacea, Stolidobranchia)with an inference of its phylogenetic position within
Styelidae. ZooKeys 857: 1–15.

Hookabe, N., Schwartz, M.L., Kajihara, H., andNorenburg, J.L. (2019) Molecular systematics of theheteronemertean genus Dushia (Nemertea, Pilidiophora),
with descriptions of D. wijnhoffae sp. nov. and D.
nigra species complex comb. nov. Zootaxa 4691:
333–358.
Ikenaga, J., Hookabe, N., Kohtsuka, H., Yoshida, M.,
and Kajihara, H. (2019) A population without female:males of Baseodiscus delineatus (Nemertea:
Heteronemertea) reproduce asexually by fragmentation.
Zoological Science 36: 348–353.
Kajihara, H. and Hookabe, N. (2019) Anterior
regeneration in Baseodiscus hempricii (Nemertea:
Heteronemertea). Tropical Natural History 19: 39–42.
Kajihara, H., Ikoma, M., Yamasaki, H., and Hiruta, S.F.
(2019) Diurodrilus kunii sp. nov. (Annelida:
Diurodrilidae) and a molecular phylogeny of the genus.
Zoological Science 36: 250–258.
Kakui, K. (2019) Shell-exchange behavior in ahermit-crab-like tanaidacean (Crustacea: Malacostraca).
Zoological Science 36: 468–470.
Park, J., Kajihara, H., and Jung, J. (2019) First recordof the interstitial annelid Pharyngocirrus uchidai(Annelida: Saccocirridae) from Korea, confirmed by
topotypic DNA barcoding data from Japan. Animal
Systematics, Evolution and Diversity 35: 33–36.
⛉Ꮫ㒊㒊㛛 ከᵝᛶ⏕≀Ꮫศศ㔝⏕≀⛉ຍ⸨ ᚭ
ᙜ◊✲ᐊ࡛ࡣ㸪㔝እ࡟⏕ᜥࡍࡿ✀ࠎࡢࢩࣙ࢘ࢪ
ࣙ࢘ࣂ࢚ࢆᑐ㇟࡟㸪ศᏊ⣔⤫ゎᯒࡸ㞟ᅋ㑇ఏᏛゎᯒࢆ⾜ࡗ࡚࠸ࡿ㸬ࡲࡓ㸪㣫⫱ࡀྍ⬟࡞✀࡟ࡘ࠸࡚ࡣ㣫⫱⣔⤫ࢆ⥔ᣢࡋ㸪ᐇ㦂ࡢࡓࡵࡢヨᩱ࡜ࡋ࡚⏝࠸࡚࠸ࡿ㸬௒ᖺᗘࡣ㸪࢟ࣀࢥ㣗ࡢࢩࣙ࢘ࢪࣙ࢘ࣂ
࢚⩌ࢆ୺࡞ᑐ㇟࡟㸪ศᏊ⣔⤫ゎᯒ࡜࢟ࣀࢥẘ⪏ᛶࡢᐇ㦂ࢆ⾜ࡗࡓ㸬1) ࢟ࣀࢥ㣗ࢩࣙ࢘ࢪࣙ࢘ࣂ࢚ࡢ⣔⤫࡜㐍໬ࢩࣙ࢘ࢪࣙ࢘ࣂ࢚⛉ࡣ⣙ 4000 ✀ࡀグ㍕ࡉࢀ࡚࠾ࡾ㸪ࡑࡢ㣗ᛶࡣᶞᾮ㣗㸪ᯝ≀㣗㸪ⲡᮏ㣗㸪࢟ࣀࢥ㣗࡜ከᒱ࡟ࢃࡓࡿ㸬ࡑࡢ࠺ࡕ㸪࢟ࣀࢥ㣗ࡣ㸪
Hirtodrosophila ᒓ 㸪 Mycodrosophila ᒓ 㸪Paramycodrosophila ᒓ㸪Zygothrica ᒓ㸪࠾ࡼࡧDrosophila ளᒓࡢ quinaria ✀⩌࡜࠸ࡗࡓศ㢮⩌࡛ㄆࡵࡽࢀࡿ㸬ࡋ࠿ࡋ࡞ࡀࡽ㸪ࡇࢀࡽࡢࢩࣙ࢘
ࢪࣙ࢘ࣂ࢚⩌ࡢ⣔⤫࡟㛵ࡍࡿ᝟ሗࡣ㠀ᖖ࡟᩿∦ⓗ࡛࠶ࡿࡇ࡜࠿ࡽ㸪࢟ࣀࢥ㣗ᙧ㉁ࡀࢩࣙ࢘ࢪ
ࣙ࢘ࣂ࢚ࡢ㐍໬㐣⛬࡛࡝࠺⋓ᚓࡉࢀ࡚ࡁࡓ࠿
ࡣ୙࡛᫂࠶ࡿ㸬ᮏ◊✲࡛ࡣ㸪ୖグศ㢮⩌ࡀྵࡲ
ࢀࡿ 139 ✀ࡢࢩࣙ࢘ࢪࣙ࢘ࣂ࢚ࢆᑐ㇟࡟㸪ᘏ࡭
26 㑇ఏᏊࡢ㓄ิ᝟ሗࢆ⏝࠸࡚ศᏊ⣔⤫ᶞࢆᵓ⠏ࡋࡓ㸬ࡑࡢ⤖ᯝ㸪⣔⤫ᶞ࡟࠾࠸࡚㸪
Hirtodrosophila ᒓ 㸪 Mycodrosophila ᒓ 㸪Paramycodrosophila ᒓ㸪࠾ࡼࡧ Zygothrica ᒓࡢ࢟ࣀࢥ㣗ࢩࣙ࢘ࢪࣙ࢘ࣂ࢚ࡣ㸪 Siphlodora ளᒓ࠾ࡼࡧ Dichaetophora ᒓࡢ㠀࢟ࣀࢥ㣗ࢩࣙ࢘ࢪࣙ࢘ࣂ࢚࡜࡜ࡶ࡟኱ࡁ࡞ࢡ࣮ࣞࢻࢆᙧᡂࡋࡓ㸬୍᪉㸪Drosophila ளᒓࡢ quinaria ✀⩌࠿ࡽ࡞ࡿࢡ࣮ࣞࢻࡣ㸪㠀࢟ࣀࢥ㣗ࡢ Drosophila ளᒓࢆྵࡴࢡ࣮ࣞࢻࡢ୰࡛ศᒱࡍࡿ࡜࠸࠺ᶞᙧࡀㄆࡵ
ࡽࢀࡓ㸬ࡇࢀࡽࡢ⤖ᯝࡣ㸪࢟ࣀࢥ㣗ᙧ㉁ࡀู⣔⤫࡛⊂❧࡟㐍໬ࡋࡓྍ⬟ᛶࢆ♧၀ࡍࡿ㸬2) ࢩࣙ࢘ࢪࣙ࢘ࣂ࢚ࡢ࢟ࣀࢥẘ⪏ᛶࡢ᳨ド࢟ࣀࢥ㣗ࢩࣙ࢘ࢪࣙ࢘ࣂ࢚ࡢ୰࡟ࡣ㸪࢟ࣀࢥ⏤᮶ࡢẘ࡛࠶ࡿȘ࢔࣐ࢽࢳࣥࡸ࢖࣎ࢸࣥ㓟࡟ᑐࡋ࡚⪏ᛶࢆᣢࡘ✀ࡢᏑᅾࡀ▱ࡽࢀ࡚࠸ࡿࡀ㸪ࡇ
ࡢᙧ㉁ࡀ࢟ࣀࢥ㣗ࡢࢩࣙ࢘ࢪࣙ࢘ࣂ࢚࡛⊂⮬࡟⋓ᚓࡉࢀࡓࡶࡢ࠿㸪࠶ࡿ࠸ࡣ㠀࢟ࣀࢥ㣗ࡢࢩࣙ࢘ࢪࣙ࢘ࣂ࢚࡛ࡶ⋓ᚓࡉࢀ࡚࠸ࡿ࠿ࡣ୙᫂
࡛࠶ࡿ㸬ࡇࡢၥ㢟ࢆ᳨ドࡍࡿࡇ࡜ࢆ┠ⓗ࡟㸪ࡇࢀࡲ࡛㸪࢟ࣀࢥ㣗ࡢࢩࣙ࢘ࢪࣙ࢘ࣂ࢚ 4 ✀㸪࠾ࡼࡧ㠀࢟ࣀࢥ㣗ࡢࢩࣙ࢘ࢪࣙ࢘ࣂ࢚ 5 ✀࡟ࡘ࠸࡚㸪Ș࢔࣐ࢽࢳࣥ 0.05mg/ml ࢆྵࡴ㣵࡜㏻ᖖࡢ
㣵࡛ᡂ⹸ࢆ⥔ᣢࡋ㸪ࡑࢀࡽࡢ⏕Ꮡ⋡ࢆẚ㍑ࡍࡿ
ࡇ࡜࡛Ș࢔࣐ࢽࢳࣥ࡟ᑐࡍࡿ⪏ᛶࢆホ౯ࡋࡓ㸬ࡑࡢ⤖ᯝ㸪࢟ࣀࢥ㣗ࡢ✀࡛ࡣఱࢀࡶȘ࢔࣐ࢽࢳࣥ࡟ᑐࡍࡿ⪏ᛶࡀㄆࡵࡽࢀࡓࡀ㸪㠀࢟ࣀࢥ㣗ࡢ✀࡛ࡣ㸪⪏ᛶࡀప࠸✀㸪࠾ࡼࡧ࢟ࣀࢥ㣗ࡢ✀࡜ྠᵝࡢ⪏ᛶࢆ♧ࡍ✀ࡀㄆࡵࡽࢀࡓ㸬ࡇࢀࡽࡢ⤖ᯝࡣ㸪Ș࢔࣐ࢽࢳࣥ⪏ᛶࡢᙧ㉁ࡀ࢟ࣀࢥ㣗ࡢ⣔⤫࡛⊂⮬࡟⋓ᚓࡉࢀࡓࡢ࡛ࡣ࡞࠸ྍ⬟ᛶࢆ♧
၀ࡍࡿ㸬
ㄅୖⓎ⾲
1. ຍ⸨ᚭ㸦2019㸧Scaptomyza ᒓ㸦཮⩟┠:ࢩࣙ࢘ࢪࣙ࢘ࣂ࢚⛉㸧ࡢ⣔⤫㐍໬㸬᪻⽝㸦ࢽ࣮ࣗࢩ࣮ࣜࢬ㸧
22: 56-65㸬
2. Chen AL, Chen CC, Katoh T, Katoh TK, Watada M,
Toda MJ, Ritchie MG, Wen SY (2019) Evolution
and diversity of the courtship repertoire in the− 21 −

࠸㞟ᅋࡣ࢜ࢫࡢ஺ᑿάຊࡶᙅ࠸㸦஺ᑿάᛶᙅ㸧㸬ࡑࡢⅭ㸪㞟ᅋ㛫஺㓄ࢆࡉࡏࡿ࡜㸪஺㓄๓㝸㞳ࡸࣛࣥࢲ࣒஺㓄ࡣ࡯࡜ࢇ࡝ぢࡽࢀࡎ㸪஺ᑿάᛶࡀᙉ࠸㞟ᅋࡢ࢜ࢫ࡜஺ᑿάᛶࡀᙅ࠸㞟ᅋࡢ࣓ࢫ㛫ࡢ஺ᑿࡀᏛ఍Ⓨ⾲㢖⦾࡟⏕ࡌ㸪㠀ᑐ⛠࡞஺㓄ࣃࢱ࣮ࣥ࡟࡞ࡿ㸬ຍ⸨ᚭ㸪୕ࢶᶫᆂ㸪Ἠ㇂ὒஅ㸪Ώ㒊ⱥ᫛㸪ᡞ⏣ṇ ᭦࡟ᮏ✀࡟ࡣᛶỴᐃࢩࢫࢸ࣒ࡢ 2 ᆺ࡜ࡣ㛵ಀ࡞᠇㸸ྠᡤⓗ࡟ศᕸࡍࡿ㏆⦕ࢩࣙ࢘ࢪࣙ࢘ࣂ࢚ 2 ✀ࡃ㸪యⰍ࡟࠾࠸࡚㸪໭ᾏ㐨ෆ࡟ᗈࡃศᕸࡍࡿ୍⯡ࡢ㈨※฼⏝࡜㑇ఏศ໬㸬᪥ᮏື≀Ꮫ఍➨ 90 ᅇ኱఍㸪ⓗ࡞⥳Ⰽᆺ࡜㸪༡໭࡟ 45 ࢟ࣟ㸪ᮾす࡟ 30 ࢟ࣟ⛬
2019 ᖺ 9 ᭶ 12 ᪥㸪኱㜰ᕷ❧኱Ꮫ㸦኱㜰ᕷ㸧㸬ࡢ⠊ᅖ࡟ศᕸࡍࡿ㯮ⰍᆺࡢⰍᙬ 2 ᆺࡶᏑᅾࡍࡿ㸬㯮Ⰽᆺࡣ㸪⥳Ⰽᆺࡢᆅᇦ㞟ᅋ㛫࡟ぢࡽࢀࡿⰍᙬࡸ
㒊㛛 ከᵝᛶ⏕≀Ꮫศศ㔝⏕≀⛉Ꮫ㒊㯮Ⰽ᮲ࡢ᭷↓࡞࡝ࡢഹ࠿࡞ኚ␗࡜ࡣⴭࡋࡃ␗࡞ࡿ㸬ゅ஭ ᩗ▱ࡲࡓ⥳Ⰽᆺ࡜㯮Ⰽᆺࡢ୰㛫ᆺࢆ♧ࡍࡼ࠺࡞ಶయࡣ
ぢࡘ࠿ࡗ࡚࠸࡞࠸㸬᫖ᖺᗘࡢ஺ᑿ⾜ືࡢᐇ㦂࡛ࡣ㸪฼⏝≧ἣ࣭◊✲ᡂᯝ୧యⰍᆺࡢ㛫࡟ࡣ஺ᑿ๓㝸㞳ࡣぢ࠸ฟࡏ࡞࠿ࡗࡓ㸬ᮏᖺᗘࡣ㸪◊✲ㄢ㢟ྡࠕᑠᆺ⏥Ẇ㢮ࡢᛶ࣭⏕ṪᵝᮏᖺᗘࡣᚓࡽࢀࡓయⰍᆺ㛫ࡢ༸ࡢᏤ໬⋡ࡸ㸪ᡂ⹸ᘧ࡞࡝ࡢ⏕≀Ꮫⓗഃ㠃࡟㛵ࡍࡿ◊✲ࠖ࡜ࡋ࡚㸪ࢤ࡟࡝ࡕࡽࡢయⰍᆺࡀฟ⌧ࡍࡿ࠿ࢆ☜࠿ࡵ㸪᫂░࡞ࣀ࣒ࢲ࢖ࢼ࣑ࢡࢫ◊✲ࢭࣥࢱ࣮ᐇ㦂⏕≀ඹྠ฼⏝యⰍࡢ 2 ᆺࡀᏑᅾࡍࡿ⌮⏤ࢆ᳨ドࡋࡓ㸬㒊㛛㸦ᐇ㦂ᐊ㸦㸰㸧㸧ࡢ฼⏝⏦ㄳࢆ⾜࠸㸪ࢱࢼ࢖ࢫ ⌧ᅾࡲ࡛㸪ࢧࢵ࣏ࣟࣇ࢟ࣂࢵࢱࡢ㉺෤༸ࡢ᭱㐺┠࡜㈅ᙧ⹸⥘࡜࠸࠺ᑠᆺ⏥Ẇ㢮࡟㛵ࡍࡿ◊✲ࢆ⾜࡞ಖᏑ᪉ἲ㸪Ꮴ໬᮲௳ࡣ☜❧ࡉࢀ࡚࠸࡞࠸㸬ࡋࡓࡗࡓ㸬୍࢝᭶㛫㸦2019 ᖺ 9 ᭶㸧ࡢ฼⏝ᮇ㛫୰࡟㸪ࡀࡗ࡚㸪ྠ㞟ᅋྠኈࡢ㞤㞝ࡢ⤌ࡳྜࢃࡏ࡛ࡢᏤ໬
༓ⴥ┴ᑠ‖࡟࡚᥇㞟ࡋࡓࢼ࣑ࢱࢼ࢖ࢫᒓࡢ 1 ✀⋡ࡶ 20㹼30㸣࡜ప࠸㸬௒ᅇ㸪㯮Ⰽᆺ♂࡜⥳Ⰽᆺ♀
㸦Zeuxo sp.㸧ࡢ㉮ගᛶࡢ᭷↓ࢆ☜ㄆࡍࡿᐇ㦂ࢆᐇࡢ⤌ࡳྜࢃࡏ࡛ࡣ 17㸣㸪⥳Ⰽᆺ♂࡜㯮Ⰽᆺ♀ࡢ⤌᪋㸪ᮏ✀ࡀ㈇ࡢ㉮ගᛶࢆ♧ࡍࡇ࡜ࢆ᫂ࡽ࠿࡟ࡋࡓ㸬ࡳྜࢃࡏ࡛ࡣ 7㸣ࡔࡗࡓ㸬࢜ࢫ࡜࣓ࢫࡢ࡝ࡕࡽࡢ
ᮏ◊✲ࡣ⚾ࡢᣦᑟᏛ⏕࡛࠶ࡿᒸᮏᬸ㌍࡟ࡼࡿ⮬↛యⰍࡀ F1 ࡢయⰍ࡟ᙳ㡪ࢆཬࡰࡍ࠿᫂ࡽ࠿࡛ࡣ࡞
ྐ⛉Ꮫ≉ู◊✲ࡢ୍⎔࡜ࡋ࡚ᐇ᪋ࡋࡓ㸬ࡲࡓྠᮇ࠸ࡀ㸪⥳Ⰽᆺ♂࡜⤌ࡳྜࢃࡏࡓ᫬ࡢ㯮Ⰽᆺ♀ࡢ༸ࡢ㛫୰࡟㸪Ἀ⦖┴࡟࡚᥇㞟ࡋࡓ㈅ᙧ⹸㢮ࡢ 1 ✀Ꮴ໬⋡ࡢపࡉࡀ㸪㯮Ⰽᆺ㞟ᅋࡀᗈࡀࡗ࡚࠸࡞࠸஦㸦Heterocypris sp.㸧ࡢ㉮ගᛶࡢ᭷↓ࢆ☜ㄆࡍࡿᐇ㦂࡟ᙳ㡪ࢆཬࡰࡋ࡚࠸ࡿྍ⬟ᛶࡀ⪃࠼ࡽࢀࡓ㸬ࢧࢵࢆᐇ᪋ࡋࡓ㸬⤖ᯝ࡟ࡘ࠸࡚ࡣ㸪⌧ᅾゎᯒࢆ㐍ࡵ࡚࣏ࣟࣇ࢟ࣂࢵࢱࡢయⰍࡣ᭱⤊⩚໬ᚋࡲ࡛ศ࠿ࡽ࡞
࠸ࡿ࡜ࡇࢁ࡛࠶ࡿ㸬ᮏ◊✲ࡣ⚾ࡢᣦᑟᏛ⏕࡛࠶ࡿ࠸㸬ࡋ࠿ࡋ࡞ࡀࡽ௒ᖺᗘࡣ㸪ᚓࡽࢀࡓᏤ໬ᗂ⹸ࢆ
᐀ീࡳࡎ࡯࡟ࡼࡿ⏕≀⛉Ꮫ◊✲ᐇ⩦ࡢ୍⎔࡜ࡋ࡚ᡂ⹸ࡲ࡛⫱࡚ࡽࢀࡎ㸪యⰍࡀ␗࡞ࡿ㞟ᅋ㛫஺㓄࡛ᐇ᪋ࡋࡓ㸬࡝ࡕࡽࡢయⰍࡀฟ⌧ࡍࡿ࠿ࡣศ࠿ࡽ࡞࠿ࡗࡓ㸬ḟᖺᗘࡣᏤ໬ᗂ⹸࠿ࡽᡂ⹸࡟⮳ࡿࡲ࡛ࡢ㣫⫱ᢏ⾡ࢆ኱Ꮫ㝔㎰Ꮫ◊✲㝔☜❧ࡋ㸪㯮Ⰽᆺࡀ⥔ᣢࡉࢀ࡚࠸ࡿ࣓࢝ࢽࢬ࣒ࡢゎᇶ┙◊✲㒊㛛 ⏕≀㈨※⛉Ꮫศ㔝᫂ࢆ┠ᣦࡍ㸬
⛅ඖ ಙ୍
Drosophila montium species group (Diptera:
Drosophilidae). Journal of Evolutionary Biology
32: 1124-1140.

▷⩟ᛶ࡛⛣ື⬟ຊ࡟ஈࡋ࠸㸪ࢧࢵ࣏ࣟࣇ࢟ࣂࢵ
ࢱ Podisma sapporensis ཬࡧ㸪࣑࢝ࢻࣇ࢟ࣂࢵࢱ
Parapodisma mikado ࢆᮦᩱ࡟⏝࠸㸪㞟ᅋ㛫ࡢ㓄അ⾜ືࡢศ໬ࡢ㐍໬ࣉࣟࢭࢫࡸ㸪⏕Ṫ㝸㞳ᶵᵓࡢゎ᫂࡟ྲྀࡾ⤌ࢇ࡛࠸ࡿ㸬≉࡟ࢧࢵ࣏ࣟࣇ࢟ࣂࢵࢱࡣ㸪ࡇࢀࡽࡢ◊✲ࡢᮦᩱ࡜ࡋ࡚㸪௨ୗࡢ 2 Ⅼ࡟࠾࠸࡚≉␗ⓗ࡛࠶ࡿ㸬1㸧ᛶỴᐃࢩࢫࢸ࣒ࡢ 2 ᆺࡀ␗ᡤⓗ࡟Ᏻᐃⓗ࡟Ꮡᅾࡍࡿ㸬໭ᾏ㐨す㒊࡟ࡣ㸪࢜ࢫ XO㸪
࣓ࢫ XX ࡛ᛶỴᐃࡍࡿ XO ࣮ࣞࢫ㞟ᅋࡀ㸪໭ᾏ㐨ᮾ㒊࡟ࡣ࢜ࢫ neo-XY㸪࣓ࢫ neo-XX ࡛ᛶỴᐃࡍࡿ
neo-XY ࣮ࣞࢫ㞟ᅋࡀศᕸࡍࡿ㸬2㸧஺ᑿάᛶ(࢜ࢫࡢ஺ᑿάຊ࡜࣓ࢫࡢ஺ᑿᣄྰຊ)ࡀᆅᇦ㞟ᅋ࡛␗࡞ࡿ㸬ᮏ✀ࡢ࣓ࢫࡣ࢜ࢫ࡟ᑐࡋ࡚஺ᑿᣄྰ⾜ືࢆ♧ࡍࡀ㸪࣓ࢫࡢ஺ᑿάຊࡀᙉ࠸㞟ᅋࡣ࢜ࢫࡢ஺ᑿ
άຊࡶᙉࡃ㸦஺ᑿάᛶᙉ㸧㸪࣓ࢫࡢ஺ᑿᣄྰຊࡀᙅ

ᇶ┙◊✲㒊㛛 ␆⏘⛉Ꮫศศ㔝ᕝཎ Ꮫ
့ங㢮ึᮇ⬇ࢆᵓᡂࡍࡿ⣽⬊ (๭⌫) ࡣࠊ⬇ෆ࡟⭍ᡤ (⬊⬇⭍) ࡀ⏕ࡌࡿ⬇┙⬊ᮇ࡜࠸࠺ࢫࢸ࣮ࢪ
࡛ࠊෆ㒊⣽⬊ሢ (ICM) ࠾ࡼࡧᰤ㣴እ⬇ⴥ (TE) ࡟ศ໬ࡋࠊࡑࢀࡒࢀᑗ᮶⫾Ꮚ࠾ࡼࡧ⫾┙ࢆ୺࡟ᙧᡂ
ࡍࡿࠋ࣐࢘ࢫ⬇࡟࠾࠸࡚ࠊ⬇ෆ࡛┦ᑐⓗ࡟ෆഃ࠾ࡼࡧእഃ࡟఩⨨ࡍࡿ๭⌫ࡀࡑࢀࡒࢀ ICM ࠾ࡼࡧ
TE ࡟ศ໬ࡍࡿ࡜࠸࠺ࠊ
ࠕෆእࣔࢹࣝࠖࡀᥦၐࡉࢀ
࡚࠸ࡿࠋᐇ㦂ⓗ࡟ࡣࠊ⬇┙⬊ᮇ⬇࠿ࡽ ICM ࢆ༢㞳ࡍࡿࡇ࡜࡟ࡼࡾࠊICM እ࿘ࡢ๭⌫ࡢ┦ᑐⓗ఩⨨ࢆෆഃ࠿ࡽእഃ࡟ኚ໬ࡉࡏࡿࡇ࡜ࡀ࡛ࡁࡿࠋᮏ◊✲࡛ࡣࠊ࢘ࢩ࠾ࡼࡧ࣐࢘ࢫ༢㞳 ICM ࡢྛ๭⌫ࡀ఩⨨㛵ಀࡢኚ໬ࢆㄆ㆑ࡋࠊಶయⓎ⏕ࢆᨭᣢࡍࡿᶵ⬟ⓗTE ࡢ෌⏕⬟ࢆಖᣢࡋ࡚࠸ࡿࡇ࡜ࢆ᳨ドࡍࡿࡓࡵ− 22 −

࡟ࠊ⭍෌ᙧᡂ⬇࡟࠾ࡅࡿಶయⓎ⏕⬟ࢆẚ㍑ࡍࡿࡇ࡜࡜ࡋࡓࠋ༢㞳 ICM ࠿ࡽෆእࣔࢹࣝ࡟ᚑ࠸෌ฟ⌧ࡋࡓ TE
ࡀಶయⓎ⏕ᨭᣢ⬟ࢆ᭷ࡍࡿ࡞ࡽࡤࠊ⭍෌ᙧᡂ⬇ࡣᏊᐑෆ࡛⫾┙ࢆᙧᡂࡋࠊዷፎ‶ᮇࡲ࡛ࡢⓎ⏕ࢆ᏶㐙࡛ࡁࡿࡣࡎ࡛࠶ࡿࠋࡑࡇ࡛ࠊ࣐࢘ࢫ࠾ࡼࡧ࢘ࢩ
⭍෌ᙧᡂ⬇ࢆ௬ぶࡢᏊᐑ࡟⛣᳜ࡋࡑࢀࡽࡢⓎ⏕⬟ࢆㄪ࡭ࡓࠋ࣐࢘ࢫ⭍෌ᙧᡂ⬇ࡢ⏕Ꮡ⫾Ꮚࡣㄆࡵࡽ
ࢀࡎࠊ࢘ࢩ⭍෌ᙧᡂ⬇࠿ࡽ୍㢌ࡢฟ⏕ಶయࡀᚓࡽ
ࢀࡓࠋ⥆࠸࡚ࠊ୧✀ࡢ㏻ᖖ⬇࡜⭍෌ᙧᡂ⬇࡟࠾࠸
࡚ࠊICM ࠿ࡽὴ⏕ࡍࡿཎጞෆ⬇ⴥࡢ࣐࣮࣮࡛࢝࠶
ࡿ SOX17 ࡢᒁᅾࢆẚ㍑ࡋࡓࠋ࢘ࢩ㏻ᖖ⬇࡛ࡣࠊ
SOX17 ࡣ᪩ᮇ⬇┙⬊ᮇࡢ TE ࡛ࡶⓎ⌧ࡋ࡚࠸ࡓࡀࠊ
࣐࢘ࢫ㏻ᖖ⬇࡛ࡣᚋᮇ⬇┙⬊ᮇ࡛ึࡵ࡚Ⓨ⌧ࡋTE ࡟ᒁᅾࡍࡿࡇ࡜ࡣ࡯ࡰ࡞࠿ࡗࡓࠋ୍᪉⭍෌ᙧᡂ⬇࡛ࡣࠊ࠸ࡎࢀࡢ✀࡟࠾࠸࡚ࡶ෌ฟ⌧ TE ࡛ SOX17
ࡢⓎ⌧ࡀ᳨ฟࡉࢀࡓࠋ௨ୖࡼࡾࠊ༢㞳 ICM ࠿ࡽ෌ฟ⌧ࡋࡓ TE ࡢⓎ⏕ᨭᣢ⬟࡟ࡣ✀㛫ᕪࡀ࠶ࡾࠊࡇࢀ
ࡣ TE ࡟࠾ࡅࡿ SOX17 ࡢᒁᅾࡢ㐪࠸࡟ཎᅉࡀ࠶ࡿ
࡜⪃࠼ࡽࢀࡓࠋ
ㄽᩥⓎ⾲
Kohri N, Akizawa H, Iisaka S, Bai H, Yanagawa Y,
Takahashi M, Komatsu M, Kawai M, Nagano M,
Kawahara M. Trophectoderm regeneration to support
full-term development in the inner cell mass isolated
from bovine blastocyst.
Journal of Biological
Chemistry. 2019; 294(50): 19209-19223.

኱Ꮫ㝔ᩍ⫱Ꮫ◊✲㝔ᩍ⫱Ꮫ㒊㛛 ೺ᗣయ⫱Ꮫศ㔝ᒣ௰ ຬ஧㑻◊✲ࢸ࣮࣐⏕≀᫬ィ࡟ࡼࡿ⾜ືࣜࢬ࣒ࡢᨭ㓄ᵝᘧ࡜⾜ືࣜࢬ࣒࠿ࡽ୰ᯡ᫬ィ࡬ࡢࣇ࢕࣮ࢻࣂࢵࢡᶵᵓࡢゎ᫂ ື≀ࡢ⾜ື࣭⏕⌮ᶵ⬟࡟ࡳࡽࢀࡿ 24 ᫬㛫࿘ᮇࡢᴫ᪥ࣜࢬ࣒ࡢⓎ᣺୰ᯡ(୰ᯡ᫬ィ)ࡣࠊ⬻ෆどᗋୗ㒊
ど஺ཫୖ᰾(Suprachiasmatic nucleus: SCN)࡟ᒁᅾࡍ
ࡿࠋSCN ࡣࠊእ⏺ࡢ᫨ኪኚ໬㸦᫂ᬯࢧ࢖ࢡࣝ㸧ࢆ୺࡞ྠㄪᅉᏊ࡜ࡋ࡚⮬㌟ࡢෆᅉᛶ࿘ᮇࢆ᫂ᬯࢧ࢖
ࢡࣝࡢ࿘ᮇ࡟ྠㄪࡉࡏࡿ࡜ྠ᫬࡟ࠊ඲㌟࡟Ꮡᅾࡍࡿᮎᲈ᫬ィ࡟᫬้᝟ሗࢆఏ㐩ࡋࠊ⾜ື࡜⏕⌮ᶵ⬟ࢆ᫬㛫ⓗ࡟⤫ྜࡋ࡚࠸ࡿࠋ⏕≀᫬ィࡢࣜࢬ࣒࿘ᮇ
ࡸ఩┦࡟ᙳ㡪ࡍࡿ⎔ቃᅉᏊࢆྠㄪᅉᏊ࡜ࡼࡧࠊ⏕≀᫬ィ࡟࡜ࡗ࡚᭱ࡶᙉຊ࡞ྠㄪᅉᏊࡣ᫂ᬯࢧ࢖ࢡ
࡛ࣝ࠶ࡿࡀࠊ⩦័ⓗ࡞㐠ືࡣ᫂ᬯࢧ࢖ࢡࣝࡢᏑᅾ
ࡋ࡞࠸ᜏᖖ⎔ቃୗ࡟࠾࠸࡚⏕≀᫬ィ࡟ไᚚࡉࢀࡿ
ࡇ࡜ࡀ᝿ᐃࡉࢀࡿ⾜ືࣜࢬ࣒ࡢࣇ࣮ࣜࣛࣥ࿘ᮇࢆ
ኚ໬ࡉࡏࡿࡇ࡜ࡀሗ࿌ࡉࢀ࡚࠸ࡿࠋࡋ࠿ࡋࠊ⩦័ⓗ࡞㐠ືࡀ୰ᯡ᫬ィ࡛࠶ࡿ SCN ࡟ᑐࡋ࡚࡝ࡢࡼ࠺

࡟ᙳ㡪ࡋࠊ⾜ືࣜࢬ࣒ࢆኚ໬ࡉࡏࡿࡢ࠿࡟ࡘ࠸࡚
ࡣ᫂ࡽ࠿࡟ࡉࢀ࡚࠸࡞࠸ࠋᙜ◊✲ᐊ࡛ࡣࠊ᫖ᖺ 2᭶ࡼࡾࢤࣀ࣒ࢲ࢖ࢼ࣑ࢡࢫ◊✲ࢭࣥࢱ࣮ᮾᲷ࡟࠾
࠸࡚ୖグㄢ㢟ࢆゎỴࡍ࡭ࡃࠊ᪂ࡓ࡟ື≀ᐇ㦂ᐊࢆࢭࢵࢺ࢔ࢵࣉࡋ◊✲ࢆ㛤ጞࡋࡓࠋ2019 ᖺᗘࡣࠊᜏ
ᖖ⎔ቃୗ࡛⾜ືࣜࢬ࣒ࢆ㛗ᮇ㛫࡟ࢃࡓࡾィ ྍ⬟࡞ ᐃ⿦⨨ࢆࢭࢵࢺ࢔ࢵࣉࡋࠊ40 ༉ࡢ࣐࢘ࢫࡢ⾜ືࣜࢬ࣒ࢆྠ᫬࡟ィ ࡛ࡁࡿࡼ࠺࡟࡞ࡗࡓࠋࡲࡓࠊ
᫬ィ㑇ఏᏊ Period1 ࡢࣉ࣮ࣟࣔࢱ࣮ୗὶ࡟࣍ࢱࣝ
ࡢⓎගࢱࣥࣃࢡ㉁ Luciferase 㑇ఏᏊࢆᑟධࡋࡓࢺ
ࣛࣥࢫࢪ࢙ࢽࢵࢡ࣐࢘ࢫ㸦Period1-luc ࣐࢘ࢫ㸧ࢆ⏝࠸࡚ࠊSCN ࡢ᫬ィ㑇ఏᏊⓎ⌧ࣜࢬ࣒ࢆࢫࣛ࢖ࢫ
ࣞ࣋ࣝ࠾ࡼࡧ୍⣽⬊࡛ࣞ࣋ࣝィ ྍ⬟࡞ࢩࢫࢸ࣒
ࡢࢭࢺ࢔ࢵࣉࢆ᏶஢ࡋࡓࠋ௒ᚋࠊࡇࢀࡽࡢࢩࢫࢸ
࣒ࢆ฼⏝ࡋ࡚ࠊ⩦័ⓗ࡞㐠ືࡀ⏕≀᫬ィ୰ᯡ࡟୚࠼ࡿᙳ㡪ࢆಶయࣞ࣋ࣝ࠾ࡼࡧศᏊ࡛ࣞ࣋ࣝ᫂ࡽ࠿
࡟ࡍ࡭ࡃ◊✲ࢆ㐍ࡵ࡚࠸ࡁࡓ࠸ࠋ

኱Ꮫ㝔ᕤ
ᕤᏛ◊✲㝔
ᛂ⏝≀⌮Ꮫ㒊㛛 㔞Ꮚ≀ᛶᕤᏛศ㔝୹⏣ ⪽㸦⣧Ỉ฼⏝㸧Ꮫ⾡ㄽᩥ
Yasuzuka, S., Uji, S., Sugiura, S., Terashima, T.,
Nogami, Y., Ichimura, K., and Tanda, S. (2019)"Highly Isotropic In-plane Upper Critical Field in the
Anisotropic s-Wave Superconductor 2H -NbSe2",
Journal of Superconductivity and Novel Magnetism
doi.org/10.1007/s10948-019-05333-z.
Kitou, S., Nakano, A., Kobayashi, S., Sugawara, K.,
Katayama, N., Maejima, N., Machida, A., Watanuki, T.,
Ichimura, K., Tanda, S., Nakamura, T., and Sawa, H.
(2019) "Effect of Cu Intercalation and Pressure on
Excitonic Interaction in 1T-TiSe2", Physical Review B
99: 104109-1-10.
Ꮫ఍Ⓨ⾲ᮾἨ⍞ᕼ㸪㏕⏣ᑘோ㸪୹⏣⪽㸸Ru 㓟໬≀㉸ఏᑟⷧ⭷ࡢ㛤ᣅ㸬2019 ᖺ➨ 80 ᅇᛂ⏝≀⌮Ꮫ఍⛅ᏘᏛ⾡
ㅮ₇఍㸪2019 ᖺ 9 ᭶ 18-21 ᪥㸪໭ᾏ㐨኱Ꮫᮐᖠ࢟
ࣕࣥࣃࢫ㸦ᮐᖠᕷ㸧㸬࢚ࢿࣝࢠ࣮⎔ቃࢩࢫࢸ࣒㒊㛛ᛂ⏝࢚ࢿࣝࢠ࣮ࢩࢫࢸ࣒ศ㔝⏣㒊 ㇏㸦⣧Ỉ฼⏝㸧Ⓨ⾲ㄽᩥ
Kitami, Y., Tabe, Y., and Chikahisa, T. (2019) Controlof the Balance between Vapor and Heat Transfer for
the Reduction of Oxygen Transport Resistance in High
Current Density PEFC Operation. ECS Transactions
92(8): 213-221.

− 23 −

Ꮫ఍Ⓨ⾲㣤฼ᣅᐇ㸪బ➉Ꮥಖ㸪ቨ㇂ᑗ⏕㸪⏣㒊㇏㸪㏆ஂṊ⨾㸸PEFC ゐ፹ᒙෆࡢ㓟⣲㍺㏦᢬ᢠホ౯ἲ࡜ᵓ㐀ᙳ㡪ゎᯒ㸬➨ 56 ᅇ᪥ᮏఏ⇕ࢩ࣏ࣥࢪ࣒࢘㸪2019 ᖺ 5
᭶ 29 ᪥㸪࠶ࢃࡂࢇ࣮࣍ࣝ ᚨᓥ┴㒓ᅵᩥ໬఍㤋㸦ᚨᓥᕷ㸧㸬▮⏣῱భ㸪㣤฼ᣅᐇ㸪⏣㒊㇏㸪㏆ஂṊ⨾㸸㓟⣲㍺㏦᢬ᢠపῶࢆ┠ᣦࡋࡓⓑ㔠ᢸᣢࢢࣛࣇ࢙ࣥࡢ
PEFC ゐ፹ᒙ࡬ࡢ฼⏝࡜ࡑࡢᛶ⬟ホ౯㸬➨ 56 ᅇ᪥ᮏఏ⇕ࢩ࣏ࣥࢪ࣒࢘㸪2019 ᖺ 5 ᭶ 29 ᪥㸪࠶ࢃࡂࢇ࣮࣍ࣝ ᚨᓥ┴㒓ᅵᩥ໬఍㤋㸦ᚨᓥᕷ㸧㸬

Yada, K. and Tabe, Y.: Development of Graphene-BasedPEFC Catalyst Layer for Reduction of Oxygen
Transport Resistance. 236th ECS meeting, 2019 ᖺ 10
᭶ 14 ᪥, Hilton Atlanta (Atlanta, USA).
Tabe, Y., Yada, K., Iiri, T., and Chikahisa, T.:
EXPERIMENTAL EVALUATION OF OXYGENTRANSPORT RESISTANCES AND INFLUENCE
OF CATALYST LAYER STRUCTURE IN PEFC. The
Second Pacific Rim Thermal Engineering Conference,
2019 ᖺ 12 ᭶ 17 ᪥, Hyatt Regency Maui Resort & Spa(Maui, USA)㸬

ᑠᒣෆ๰ኴ㸪⏣㒊㇏㸪㏆ஂṊ⨾㸸ࣞࢻࢵࢡࢫࣇࣟ
኱Ꮫ㝔་Ꮫ◊✲㝔㝔࣮㟁ụ࡟࠾ࡅࡿ㟁ᴟᵓ㐀࠾ࡼࡧ㟁ゎᾮὶື᮲௳ࡀ
་ṑᏛ⥲ྜ◊✲Ჷ ୰ኸ◊✲㒊㛛ᛶ⬟࡟ཬࡰࡍᙳ㡪㸬➨ 56 ᅇ᪥ᮏఏ⇕ࢩ࣏ࣥࢪ࣒࢘㸪 ᒣ㔝㎶ ㈗ಙ
2019 ᖺ 5 ᭶ 29 ᪥㸪࠶ࢃࡂࢇ ࣮࣍ࣝᚨᓥ┴㒓ᅵᩥ໬఍㤋㸦ᚨᓥᕷ㸧㸬⚄⤒ᅇ㊰⌮ㄽ࡟ࡼࢀࡤ⣲Ꮚࡢฟຊ㛵ᩘࡢ≉ᛶ࡟౫Ꮡࡋࠊ᝟ሗ࢟ࣕࣜ࢔ࡀỴࡲࡿࠋࢫࣃ࢖ࢡࡣ⚄⤒႐ከぢ♸ᕼ㸪⏣㒊㇏㸪㏆ஂṊ⨾㸸PEFC 㧗㟁ὶᐦᗘ⣽⬊ࡀ㐣Ώ≧ែ࡟࠶ࡿ࡜ࡁ࡟⏕ࡌࡿࡓࡵࠊࢫࣃ࢖㐠㌿࡟࠾ࡅࡿỈ⵨Ẽ㍺㏦࡜⇕ఏᑟࡢࣂࣛࣥࢫไᚚ
ࢡ⏕ᡂࡣ㐣ཤࡢ⚄⤒άື࡟౫Ꮡࡍࡿࡇ࡜ࡀሗ࿌ࡉ
࡟ࡼࡿ㓟⣲㍺㏦᢬ᢠపῶ㸬➨ 56 ᅇ᪥ᮏఏ⇕ࢩ࣏ࣥࢀ࡚࠸ࡿ㸦Segundo et al.Neuroscience 1994, Yamanobeࢪ࣒࢘㸪2019 ᖺ 5 ᭶ 30 ᪥㸪࠶ࢃࡂࢇ ࣮࣍ࣝᚨᓥ
et al. Biosystems 1998㸧ࠋࡲࡓࠊ⚄⤒⣽⬊ࡣࠊᣑᩓ㐣┴㒓ᅵᩥ໬఍㤋㸦ᚨᓥᕷ㸧㸬⛬࡛㏆ఝࡉࢀࡿ࢖࢜ࣥࢳࣕࢿࣝࣀ࢖ࢬࠊࢩࢼࣉࢫ
ᖹ஭㈼㸪⏣㒊㇏㸪㏆ஂṊ⨾㸸PEFC ịⅬୗ㉳ືࡢࡓᑠ⬊ࡢ⮬Ⓨⓗᨺฟ࡟ࡼࡿࢪࣕࣥࣉࣀ࢖ࢬ࡞࡝ࢆᣢ
ࡵࡢྵỈ≧ែ࡟ᛂࡌࡓ㐠㌿ไᚚἲ㸬➨ 24 ᅇືຊ࣭ࡘ☜⋡ⓗ࡞ᣲືࢆࡍࡿ⣲Ꮚ࡛ࡶ࠶ࡿࠋࡇࢀࡽࡢࣀ
࢚ࢿࣝࢠ࣮ᢏ⾡ࢩ࣏ࣥࢪ࣒࢘㸪2019 ᖺ 6 ᭶ 20 ᪥㸪࢖ࢬ࡟ࡼࡾ⚄⤒⣽⬊ࡢᛂ⟅≉ᛶࡀኚࢃࡿࡇ࡜ࡶண
ᮾி኱Ꮫ⏕⏘ᢏ⾡◊✲ᡤ㸦ᮾி㒔┠㯮༊㸧㸬᝿ࡉࢀࡿࠋࡑࡇ࡛ࠊྛ⚄⤒⣽⬊࡟࠾࠸࡚㐣Ώᛂ⟅≉ᛶ࡜ࣀ࢖ࢬࡢᙳ㡪ࢆ཯ᫎࡋࡓฟຊ㛵ᩘࡢ≉ᛶࢆす⏣ᑦຌ㸪⏣㒊㇏㸪㏆ஂṊ⨾㸸ࣞࢻࢵࢡࢫࣇ࣮ࣟ
ᐇ㦂ⓗ࡟ồࡵࡿࡇ࡜ࡀࠊ᝟ሗ࢟ࣕࣜ࢔ࢆゎ᫂ࡍࡿ㟁ụ࡟࠾ࡅࡿ㞟⣙୺せᅉᏊ࡟ࡼࡿᛶ⬟ホ౯࡜㧗ຠ⋡໬㸬➨ 24 ᅇືຊ࣭࢚ࢿࣝࢠ࣮ᢏ⾡ࢩ࣏ࣥࢪ࣒࢘㸪 ࡓࡵ࡟ᚲせ࡛࠶ࡿ࡜⪃࠼ࡽࢀࡿࠋᐇ㦂࡛⚄⤒⣽⬊ࡢฟຊ㛵ᩘࢆㄪ࡭ࡿ᪉ἲࢆᵓ⠏ࡍࡿࡓࡵࠊ☜⋡ⓗ2019 ᖺ 6 ᭶ 20 ᪥㸪ᮾி኱Ꮫ⏕⏘ᢏ⾡◊✲ᡤ㸦ᮾ⚄⤒⣽⬊ࣔࢹࣝࡢⓎⅆάືࡀ࡝ࡢࡼ࠺࡞☜⋡㐣⛬ி㒔┠㯮༊㸧㸬
࡛࠶ࡿ࠿▱ࡿࡇ࡜ࡀ㔜せ࡛࠶ࡿࠋࡇࡢࡼ࠺࡞ၥ㢟᭷⃝្⣖㸪Can Enes Muhammet㸪⏣㒊㇏㸪㏆ஂṊ⨾㸸ព㆑ࡢࡶ࡜ࠊ௒ᖺᗘࡣ௨ୗࡢ㸱ࡘࡢࢸ࣮࣐࡟㛵ࡋ
PEFC ࢞ࢫᣑᩓᒙෆࡢᾮỈᣲື࡟ཬࡰࡍ⃿ࢀᛶᙳ࡚◊✲ࢆᐇ᪋ࡋࡓࠋ
㡪ゎᯒ㸬᪥ᮏᶵᲔᏛ఍ 2019 ᖺᗘᖺḟ኱఍㸪2019㸯㸬ࢩࢼࣉࢫࣀ࢖ࢬ࠾ࡼࡧ࢖࢜ࣥࢳࣕࢿࣝࣀ࢖ࢬ
ᖺ 9 ᭶ 11 ᪥㸪⛅⏣኱Ꮫᡭᙧ࢟ࣕࣥࣃࢫ㸦⛅⏣ᕷ㸧㸬ࢆᣢࡘ⚄⤒⣽⬊ࣔࢹࣝࡢ☜⋡㐣⛬ࡢ₞㏆ᒎ㛤⌮ㄽࢆ⏝࠸᥎⛣☜⋡ᐦᗘ㛵ᩘࡢ₞㏆ᒎ㛤ࢆィ⟬ࡋ࡚ࡁ
Zhan, J., Hirai, K., and Tabe, Y.㸸Study on Cold Start
Characteristics of PEFC with Adiabatic Temperature Rise㸬 ࡓࡀࠊࡇࢀ࡛ᑟ࠿ࢀࡿ᥎⛣☜⋡ࡢᘧ࡟ࡣ㧗ḟࡢ㏲ḟ✚ศࡀ⌧ࢀࡿࠋࡇࢀࡀࢿࢵࢡ࡜࡞ࡾ᥎⛣☜⋡ᐦ᪥ᮏᶵᲔᏛ఍⇕ᕤᏛࢥࣥࣇ࢓ࣞࣥࢫ㸪2019 ᖺ 10ᗘ㛵ᩘࡢ₞㏆ᒎ㛤ࡢィ⟬ࡀ㝈ࡽࡓሙྜ࡟ࡋ࠿࡛ࡁ
᭶ 12 ᪥㸪ྡྂᒇᕤᴗ኱Ꮫᚚჾᡤᆅ༊㸦ྡྂᒇᕷ㸧㸬࡞࠿ࡗࡓࠋࡋ࠿ࡋࠊ௒ᖺᗘࡢ◊✲࡟ࡼࡾࠊࣀ࢖ࢬ
Osanai 㸪 S., Tabe, Y., and Chikahisa, T.: Effect of㡯ࡀ࠶ࡿ᮲௳ࢆ‶ࡓࡍ࡜ࡁࠊࡇࡢไ⣙ࢆྲྀࡾ㝖ࡅ
Electrode Structure and Electrolyte Flow on Performanceࡿࡇ࡜ࡀ⌮ㄽⓗ࡟ศ࠿ࡗࡓࠋ
of Redox Flow Battery. 236th ECS meeting, 2019 ᖺ 10㸰㸬ᣑᩓ㐣⛬ࢆྵࡴ FitzHugh-Nagumo ࣔࢹࣝࡢ᥎⛣᭶ 14 ᪥, Hilton Atlanta (Atlanta, USA).
☜⋡ᐦᗘ㛵ᩘࡢ₞㏆ᒎ㛤ࢆィ⟬ࡋࡓࠋ₞㏆ᒎ㛤ࡢ➨Hirai, K. and Tabe, T.: Water Transport in PEFC Cold୍㡯ࡣ࢞࢘ࢫศᕸ࡜࡞ࡿࡀࠊFitzHugh-Nagumo ࣔࢹ
Startup with Temperature Rise Simulating AdiabaticࣝࡢỴᐃㄽⓗゎࡣゎᯒⓗ࡟ゎࡃࡇ࡜ࡀ࡛ࡁࡎࠊྠࡌ
Condition. 236th ECS meeting, 2019 ᖺ 10 ᭶ 14 ᪥,ࡃࡇࡢࣔࢹࣝࡢኚศ᪉⛬ᘧࡶゎᯒⓗ࡟ゎࡃࡇ࡜ࡀ
Hilton Atlanta (Atlanta, USA).
࡛ࡁ࡞࠸ࡓࡵࠊ࢞࢘ࢫศᕸࡢศᩓඹศᩓ⾜ิࡢィ⟬ࡀᅔ㞴࡜࡞ࡗ࡚࠸ࡓࠋᡃࠎࡣ FitzHugh-Nagumo ࣔࢹ− 24 −

ࣝࡢỴᐃㄽⓗゎࡢᩘ್ゎࠊኚศ᪉⛬ᘧࡢᩘ್ᚋ㏥
ᇶᮏゎࠊࣟࣥࣂ࣮ࢢ✚ศἲࢆ⤌ࡳྜࢃࡏࡿࡇ࡜࡛
ࡇࢀࡽࡢᅔ㞴ࢆඞ᭹ࡋࡓࠋࡉࡽ࡟ࠊࡇࡢᩘ್ィ⟬ࡢ᭷ຠᛶࢆ☜࠿ࡵࡿࡓࡵࠊ᥎⛣☜⋡ᐦᗘ㛵ᩘࡢ₞㏆ᒎ㛤࡜ࣔࣥࢸ࢝ࣝࣟࢩ࣑࣮ࣗࣞࢩࣙࣥ࡟ࡼࡿ᥎
⛣☜⋡࡜ࡢẚ㍑ࢆࡋࠊࡑࡢ⢭ᗘࢆホ౯ࡋࡓࠋ㸱㸬࢖࢜ࣥࢳࣕࢿࣝࡢ☜⋡ⓗ㛤㛢ࡢࡓࡵࣀ࢖ࢬࡀ
⏕ࡌࡿࡀࠊࡇࡢࣀ࢖ࢬࡀ࢖࢜ࣥࢳࣕࢿࣝᩘࡢቑຍ
࡜࡜ࡶ࡟࡝ࡢࡼ࠺࡞☜⋡㐣⛬࡛㏆ఝࡉࢀࡿ࠿ࡣࠊ
⚄⤒⣽⬊ࣔࢹࣝࡢᘧࡢ࡝ࡇ࡟ࠊ࡝ࡢࡼ࠺࡞ࣀ࢖ࢬ
ࢆຍ࠼ࢀࡤⰋ࠸ࡢ࠿࡜࠸࠺ၥ㢟࡜㛵㐃ࡋ࡚࠾ࡾࠊ
⚄⤒⣽⬊ࣔࢹࣝࡢᣲືࡢゎᯒ࡟ᚲせ࡞᝟ሗ࡛࠶ࡿࠋ
⚄⤒⣽⬊࡟Ꮡᅾࡍࡿ㟁఩౫Ꮡᛶ࢖࢜ࣥࢳࣕࢿࣝࡣ
ࡑࡢᣲືࡀ࣐ࣝࢥࣇ㐃㙐ࢆ⏝࠸⾲ࡉࢀࡿሙྜࡀ࠶
ࡿࠋࡇࡢሙྜ࡟ࡘ࠸࡚☜⋡ゎᯒࡢᡂᯝ࡛࠶ࡿὶయ
ຊᏛᴟ㝈ࡢࢸࢡࢽࢵࢡࢆ⏝࠸ࠊ࢖࢜ࣥࢳࣕࢿࣝࣀ
࢖ࢬࡀ࠶ࡿ☜⋡㐣⛬࡛㏆ఝࡉࢀࡿ࠿௚ࡢ◊✲⪅࡟ࡼࡾ♧ࡉࢀࡓࠋࡋ࠿ࡋࠊࡇࡢ㏆ఝࡣኚᩘࡢ⠊ᅖࡀ⏕⌮Ꮫⓗ࡟ጇᙜ࡜ࡍࡿ⠊ᅖࢆ㉸࠼࡚ࡋࡲ࠺ḞⅬࡀ࠶ࡗࡓࠋᡃࠎࡣ࠶ࡿᩘᏛⓗ࡞ࢸࢡࢽࢵࢡࢆ⏝࠸ࠊࡇࡢḞⅬࢆゎᾘࡋࡓࠋ
Ꮫ఍Ⓨ⾲
1. Yamanobe, T., Asymptotic expansion of a stochastic
FitzHugh-Nagumo model㸪➨㸳㸵ᅇ᪥ᮏ⏕≀≀⌮Ꮫ఍ᖺ఍㸪㸰㸮㸯㸷ᖺ㸷᭶㸰㸳᪥㸪ࢩ࣮࢞࢖࢔ࢥࣥ࣋ࣥࢩࣙࣥࢭࣥࢱ࣮㸪ᐑᓮྲྀࡋࠊ⬻ෆࡢ %'( ࡜⚄⤒ఏ㐩≀㉁ཬࡧࡑࡢ㛵㐃≀㉁ࠊ⫢⮚୰ࡢ %'(ࠊ⾑ᾮ୰ࡢ⏥≧⭢࣍ࣝࣔࣥࢆᐃ㔞ࡋࡓࠋ
⤖ᯝ࡜⪃ᐹ㸸 㧗⃰ᗘ⩌ࡢ⬻࠿ࡽ %'( ࡀ᳨ฟࡉࢀࡓࠋẕయ⤒⏤࡛྾཰ࡉࢀࡓ %'( ࡣࠊ ࢝᭶㏆ࡃ⤒㐣ࡋࡓᚋࡶ⬻ෆ࡟ṧ␃ࡍࡿࡇ࡜ࡀศ࠿ࡗ
ࡓࠋప⃰ᗘ⩌ࡢ⬻࠿ࡽ %'( ࡣ᳨ฟࡉࢀ࡞࠿ࡗ
ࡓࠋ㧗⃰ᗘ⩌ࠊప⃰ᗘ⩌࡜ࡶ࡟⫢⮚࠿ࡽ %'(ࡣ᳨ฟࡉࢀ࡞࠿ࡗࡓࠋ㧗⃰ᗘ⩌ࡢ⬻࡛ࡣࠊ⚄⤒ఏ㐩≀㉁ࢭࣟࢺࢽࣥࡀప⃰ᗘ⩌࣭⤫ไ⩌ࡼࡾῶᑡࡋ
ࡓࠋឤ᝟㞀ᐖࡢᝈ⪅࡛ࡣ⬻ෆࢭࣟࢺࢽࣥࡀపୗࡋ
࡚࠸ࡿࡇ࡜࠿ࡽࠊ㧗⃰ᗘ⩌࡟ࡶឤ᝟㞀ᐖࡀ⏕ࡌ࡚࠸ࡓྍ⬟ᛶࡀ࠶ࡿࠋࡉࡽ࡟ࠊ㧗⃰ᗘ⩌࡛ࡣ⾑୰ࣜ
ࣂ࣮ࢫ 7 㔞ࡀప⃰ᗘ⩌࣭⤫ไ⩌ࡼࡾୖ᪼ࡋࠊ⏥≧⭢࣍ࣝࣔࣥ 7 㔞࡟ῶᑡഴྥࡀㄆࡵࡽࢀࡓࠋ⏥≧⭢࣍ࣝࣔࣥࡣ⬻⚄⤒⣔ࡢⓎ㐩ࡸࢿࢵࢺ࣮࣡ࢡᙧᡂ࡟
ᚲ㡲ࡢ࡛࣍ࣝࣔࣥ࠶ࡿࡇ࡜࠿ࡽࠊㄆ▱ᶵ⬟ࡢⓎ㐩ࡀ㜼ᐖࡉࢀࡓྍ⬟ᛶࡶ࠶ࡿࠋࡇࢀࡲ࡛ࡢ◊✲࠿ࡽࠊ㧗⃰ᗘ⩌ࡣ௚ಶయ࡜᥋ゐࡍࡿ♫఍ⓗሙ㠃࡛ࠊ࿘Ἴᩘ 㹼N+] ࡢ୙ᛌ࡞ឤ᝟≧ែࢆ♧ࡍ㉸㡢ἼⓎኌࡀቑ኱ࡍࡿࡇ࡜ࡀࢃ࠿ࡗ࡚࠸ࡿࠋ%'( ࡢస⏝࡟ࡼࡗ࡚⬻ෆࢭࣟࢺࢽࣥࡀῶᑡࡋࠊឤ᝟㞀ᐖࡀ㧗ࡲࡗ࡚௰㛫ࡸ␗ᛶ࡜᥋ゐࡍࡿ♫఍ⓗሙ㠃࡛୙ᛌ࡞ឤ᝟≧ែࢆ♧ࡍ㉸㡢Ἴࢥ࣑ࣗࢽࢣ࣮ࢩࣙࣥࢆ⾜ࡗࡓ࡜࠸࠺ࢩࢼࣜ࢜ࡀ⪃࠼ࡽࢀࡿࠋ⏥≧⭢࣍ࣝࣔࣥపୗ࡟ࡼࡗ࡚ㄆ▱ᶵ⬟Ⓨ㐩ࡀ㜼ᐖࡉࢀࠊ♫఍ᛶࡸࢥ࣑ࣗࢽࢣ࣮ࢩࣙࣥ⬟ຊ࡟ᙳ㡪ࡋࡓྍ⬟ᛶࡶ⪃࠼ࡽࢀࡿࠋ◊✲ࢸ࣮࣐㸰኱Ꮫ㝔ᩥᏛ◊✲㝔㝔࿘⏘ᮇࡢ࢔ࣝࢥ࣮ࣝ᭚㟢ࡀࣛࢵࢺࡢ㉸㡢Ἴࢥ࣑ࣗே㛫⛉Ꮫ㒊㒊㛛 ᚰ⌮Ꮫศศ㔝ࢽࢣ࣮ࢩࣙࣥࡢⓎ㐩࡟ཬࡰࡍᙳ㡪࿴⏣ ༤⨾ ࡇࢀࡲ࡛ࡢ◊✲࠿ࡽࠊ⫾௘ᮇࡸᤵஙᮇ࡟࢔ࣝࢥ
࣮ࣝ࡟᭚㟢ࡉࢀࡓࣛࢵࢺࡣ௚ಶయ࡜᥋ゐࡍࡿ♫఍◊✲ࢸ࣮࣐㸯ⓗሙ㠃࡛ࠊ࿘Ἴᩘ 㹼N+] ࡢ୙ᛌ࡞ឤ᝟≧ែࢆ⮯⣲⣔㞴⇞๣ࢹ࢝ࣈࣟࣔࢴࣇ࢙ࢽ࣮࢚࣮ࣝࢸࣝ
㸦%'(㸧㸧ࡀࣛࢵࢺࡢ㉸㡢Ἴࢥ࣑ࣗࢽࢣ࣮ࢩࣙࣥ ♧ࡍ㉸㡢ἼⓎኌࢆ⾜࠺ࡇ࡜ࡀศ࠿ࡗࡓࠋࡑࡇ࡛ᮏ
◊✲࡛ࡣࠊ௚ಶయ࡜᥋ゐࡍࡿ♫఍ⓗ⾜ືࡀ࡝ࡢࡼ
ࡢⓎ㐩࡟ཬࡰࡍᙳ㡪⮯⣲⣔㞴⇞๣ %'( ࡣྍ⇞≀ࢆ⇞࠼࡟ࡃࡃࡋࠊ ࠺࡟ኚ໬ࡋࡓࡢ࠿ࠊ୙ᛌ࡞ឤ᝟࡜ࡣఱ࡛࠶ࡿࡢ࠿
ࢆゎ᫂ࡋࡓࠋ
ⅆ⅏ࡢᘏ↝ࢆ㜵ࡄࡇ࡜ࡀ࡛ࡁࡿࠋࡋ࠿ࡋ⬻⚄⤒⣔᪉ἲ㸸 ዷፎࣛࢵࢺࢆ  ⩌࡟ศࡅࠊ࢔ࣝࢥ࣮ࣝࢆ
ࡢⓎ㐩࡟ᚲ㡲ࡢ⏥≧⭢࣍ࣝࣔࣥࢆ㜼ᐖࡍࡿࡇ࡜࠿
ΰධࡋࡓ㣧ᩱỈࢆ୚࠼ࡓࠋ࢔ࣝࢥ࣮ࣝ⃰ᗘࡣ 㸣ࡽࠊㄆ▱ᶵ⬟ࡢ㞀ᐖࢆᘬࡁ㉳ࡇࡍྍ⬟ᛶࡀᠱᛕࡉ
ࢀ࡚࠸ࡿࠋࡑࡇ࡛ዷፎࣛࢵࢺ࡟ %'( ࢆᢞ୚ࡋࠊ ࡜ 㸣ࠊᢞ୚ᮇ㛫ࡣዷፎ 㹼 ᪥┠㸦⫾௘ᮇ㸧ࠊࡲࡓࡣ⏕ᚋ 㹼 ᪥┠㸦ᤵஙᮇ㸧࡛࠶ࡗࡓࠋ⏕ᚋ ฟ⏕ࡋࡓࣛࢵࢺࡢ㉸㡢Ἴࢥ࣑ࣗࢽࢣ࣮ࢩࣙࣥࡢኚ
᪥┠࡟௘ࣛࢵࢺࢆ㞳ஙࡉࡏࠊಶูࢣ࣮ࢪ࡛㣫⫱ࡋ
␗࡜ %'( ࡢస⏝ᶵᗎࢆ᫂ࡽ࠿࡟ࡍࡿ◊✲ࢆ⾜ࡓࠋ⏕ᚋ 㹼 ᪥࡟୙Ᏻᵝ⾜ືࢆ ᐃࡍࡿ㧗ᯫᘧࡗࡓࠋ༑Ꮠ㏞㊰ࢸࢫࢺࠊ⏕ᚋ 㹼 ᪥┠࡟  ༉ࡢࣛࢵࢺ
᪉ἲ㸸 ዷፎࣛࢵࢺࢆ  ⩌࡟ศࡅࠊ%'( ࢆᢞ࡟ࡼࡿ㜚த㐟ࡧࢸࢫࢺࠊ⏕ᚋ 㹼 ᪥┠࡟㞤㞝࣌୚ࡋࡓࠋᢞ୚㔞ࡣ㧗⃰ᗘ⩌ PJNJGD\㸦Q 㸧ࠊ࢔࡟ࡼࡿ஺ᑿ⾜ືࢸࢫࢺࠊ⏕ᚋ 㹼 ᪥┠࡟㞝ప⃰ᗘ⩌ PJNJGD\㸦Q 㸧ࠊ⤫ไ⩌ PJNJGD\
ྠኈ࡟ࡼࡿ㜚த⾜ືࢸࢫࢺࢆ⾜࠸ࠊ⾜ືࢆグ㘓ࡋ㸦Q 㸧࡜ࡋࡓࠋ%'( ࢆ⦎ங JNJGD\ ࡟࡚ゎᯒࡋࡓࠋ
ΰධࡋࠊ⮬⏤ᦤ㣗ࡉࡏࡓࠋᢞ୚ᮇ㛫ࡣዷፎ  ᪥㹼⤖ᯝ࡜⪃ᐹ㸸 ⫾௘ᮇ࢔ࣝࢥ࣮ࣝ᭚㟢⩌ࡢࣛࢵࢺฟ⏘ᚋ  ᪥┠࡛࠶ࡗࡓࠋ㉸㡢Ἴ ᐃࡀ⤊஢ࡋࡓ⏕
ࡣ୙Ᏻᵝ⾜ືࡀቑຍࡋࡓࠋࡉࡽ࡟㜚த㐟ࡧࡸ஺ᑿᚋ 㹼 ᪥┠࡟ࣛࢵࢺ࠿ࡽ⬻ࠊ⫢⮚ࠊ⾑ᾮࢆ᥇− 25 −

ሙ㠃࡛௚ಶయ࡜᥋ゐࡍࡿ㢖ᗘࡀῶᑡࡋࡓࠋ⫾௘ᮇࡢ࢔ࣝࢥ࣮ࣝ᭚㟢࡟ࡼࡾ୙Ᏻഴྥࡀ㧗ࡲࡗࡓࡇ࡜
࡟ࡼࡾࠊ௚ಶయ࡜᥋ゐࡍࡿ௰㛫㐟ࡧࡸ஺ᑿሙ㠃࡛᥋ゐࢆ㑊ࡅࠊ୙ᛌ࡞ឤ᝟ࢆ♧ࡍ㉸㡢ἼⓎኌࡀቑ኱ࡋࡓ࡜⪃࠼ࡽࢀࡿࠋᤵஙᮇ࢔ࣝࢥ࣮ࣝ᭚㟢ࣛࢵࢺ࡛ࡣ୙Ᏻഴྥ࡟ኚ໬ࡣ࡞ࡃࠊ௚ಶయ࡜ࡢ᥋ゐࢆ㑊ࡅࡿഴྥࡶ⫾௘ᮇ᭚㟢ࣛࢵࢺ࡯࡝࡛ࡣ࡞࠿ࡗࡓࠋ ࠙Ꮫ఍Ⓨ⾲ࠚ
1. Shahrier M. A. and Wada H. Acoustic characteristicsof play fighting-induced ultrasonic vocalizations injuvenile rats prenatally exposed to ethanol. 17th
International Neurotoxicology Association, September
29-October 3, 2019, Hotel Land Gut Höhne(Düsseldorf, Germany).
2. Qi Y. and Wada H. Effects of decabromodiphenyl
ether (BDE-209) on ultrasonic communication uponplay fighting in juvenile rats. 17th International
Neurotoxicology Association, September 29-October
3, 2019, Hotel Land Gut Höhne (Düsseldorf,
Germany).
3. Shahrier M. A. and Wada H. Acoustic characteristicsof play fighting-induced ultrasonic vocalizations injuvenile rats prenatally exposed to ethanol. ➨  ᅇ໭ᾏ㐨኱Ꮫ㒊ᒁᶓ᩿ࢩ࣏ࣥࢪ࣒࢘㸪 ᖺ ᭶  ᪥㸪໭ᾏ㐨኱Ꮫ་Ꮫ㒊ࣇࣛࢸ఍㤋㸦ᮐᖠᕷ㸧㸬
4. Qi Y. and Wada H. Effects of decabromodiphenyl
ether (BDE-209) on ultrasonic communication
upon play fighting in juvenile rats. ➨  ᅇ໭ᾏ㐨኱Ꮫ㒊ᒁᶓ᩿ࢩ࣏ࣥࢪ࣒࢘㸪 ᖺ  ᭶  ᪥㸪໭ᾏ㐨኱Ꮫ་Ꮫ㒊ࣇࣛࢸ఍㤋㸦ᮐᖠᕷ㸧㸬
5. ᙇ 㡼ࠊ࿴⏣༤⨾㸬༢㣫⫱࡜⩌㣫⫱ࡀᛮ᫓ᮇࣛ
ࢵࢺࡢ୙Ᏻ࠾ࡼࡧ࠺ࡘᵝ⾜ື࡟ཬࡰࡍᙳ㡪㸬➨ ᅇ໭ᾏ㐨኱Ꮫ㒊ᒁᶓ᩿ࢩ࣏ࣥࢪ࣒࢘㸪ᖺ  ᭶  ᪥㸪໭ᾏ㐨኱Ꮫ་Ꮫ㒊ࣇࣛࢸ఍㤋㸦ᮐᖠᕷ㸧㸬
6. 㔝ᓥ⏤⾰ࠊ⥏ⱙⱾࠊ࿴⏣༤⨾ࠊ⏣㎶ಙ௓ࠊ㔝ぢᒣ᱇㸬ẕぶࢆ௓ࡋࡓⓎ㐩ᮇ BDE-209 ᭚㟢࡟ࡼࡿ⬻⚄⤒⣔࠾ࡼࡧࣛࢵࢺ㉸㡢ἼⓎኌ࡬ࡢᙳ㡪ホ౯㸬➨  ᅇ⎔ቃ࣍ࣝࣔࣥᏛ఍㸪 ᖺ ᭶  ᪥㸪ᮾி኱Ꮫᘺ⏕ㅮᇽ㸦ᮾி㒔ᩥி༊㸧㸬


኱Ꮫ㝔᝟
᝟ሗ⛉Ꮫ◊
◊✲㝔
㝔
⏕࿨ே㛫᝟ሗ⛉Ꮫ㒊㒊㛛ࣂ࢖࢜࢖ࣥࣇ࢛࣐ࢸ࢕ࢡࢫศ
ศ㔝㐲⸨ ಇᚨ

᱂ᇵ✀࣭ྂ௦ࣄࣙ࢘ࢱࣥࡢศᏊ⣔⤫ゎᯒ࡜᪥ᮏࡢ
ᅛ᭷᳜≀/VSKDHULFD/EUHYLIORUD㸧ࡢྜィ  ᶆᮏ࡟
ࡘ࠸࡚ࠊ5DGVHT ࡟ࡼࡿヲ⣽࡞ከᵝᛶゎᯒࢆ⾜࠺ࡓࡵ✀Ꮚ࠿ࡽࡢ⫱ᡂ࡜ '1$ ᢳฟࢆ⾜ࡗࡓࠋຍ࠼࡚⁠㈡┴ࡢ⢖ὠ†ᗏ㑇㊧࠿ࡽⓎぢࡉࢀࡓ⣙  ୓  ༓ᖺ๓ࡢࡶࡢ࡜᥎ᐃࡉࢀࡿ✀Ꮚᶆᮏࠊឡ፾┴ࡢ᪂㇂ྂ᪂㇂㑇㊧࣭᪂㇂᳃ࣀ๓㑇㊧࠿ࡽⓎぢࡉࢀࡓᘺ⏕㹼ྂቡ᫬௦㡭࡜᥎ᐃࡉࢀࡿᯝ⓶ᶆᮏࢆධᡭࡋࠊࡇࢀ
ࡽࡢ඲㛗ࢤࣀ࣒ '1$ Ỵᐃࢆ⾜࠺ࡇ࡜ࢆ┠ⓗ࡟ '1$
ᢳฟࢆ⾜ࡗࡓࠋྂ௦㑇㊧ࡣỈᾐ࠾ࡼࡧ஝⇱ࡢ≧ែ࡛ṧ␃ '1$ ࡜࠸࠺ほⅬ࠿ࡽࡣಖᏑ≧ែࡀᝏࡃࠊ㏻
ᖖࡢᡭἲ࡟ࡼࡿ '1$ ᢳฟࡣᴟࡵ࡚㞴ࡋ࠸ࠋ௒ᅇࠊ
᪂ࡋࡃᨵⰋࡋࡓ᪉ἲ࡟ࡼࡾẚ㍑ⓗ㧗཰㔞࡛ '1$ ࢆᚓࡿࡇ࡜ࡀ࡛ࡁࡓࠋࡇࢀࡽࡢ '1$ ࡟ࡘ࠸࡚ࡣḟୡ௦ࢩ࣮ࢣࣥࢧ࡟ࡼࡿ඲㛗ࢤࣀ࣒Ỵᐃࢆ⾜࠺ணᐃ࡛࠶ࡿࠋ㞧✐࢔࣡࡜࢟ࣅࡢ㑇ఏⓗከᵝᛶ࠿ࡽ᧿ᩥ᫬௦ࡢ㎰⪔ᩥ໬࡜⮬↛⎔ቃࡢṔྐࢆゎ᫂ࡍࡿ໭᪥ᮏࡢ᧿ᩥᩥ໬ࡢ㎰⪔ࢆ 㹼 ୡ⣖࡟Ώࡗ࡚ᨭ
࠼ࡓ㞧✐࢔࣡࡜࢟ࣅࡢ '1$ ከᆺゎᯒࢆ⾜࠺ࡇ࡜࡛ࠊ
࢔࣡࡜࢟ࣅࡢ໭᪥ᮏ࡬ࡢఏ᧛࣮ࣝࢺࡸ᱂ᇵ໬࡟࠾
ࡅࡿேⅭ㑅ᢥ࠾ࡼࡧࠊ㞧✀ᙧᡂྍ⬟࡞㏆⦕㔝⏕✀࡜ࡢ㛫ࡢ㑇ఏᏊὶືࡢ⛬ᗘ࠿ࡽࠊ໭᪥ᮏࡢṔྐ࡟࠾ࡅࡿ㎰⪔ᩥ໬࡜⮬↛⎔ቃࡢ┦஫స⏝ࢆ᫂ࡽ࠿࡟
ࡍࡿࡇ࡜ࢆ┠ⓗ࡜ࡍࡿࠋ
5$'VHTἲ࡟ࡼࡾᚓࡿ '1$ከᆺࢹ࣮ࢱ࠿ࡽࠊศᏊ㐍໬ࠊ㞟ᅋ㑇ఏᏛⓗ࡞ᡭἲࢆ⏝࠸࡚ゎᯒࢆ⾜࠸ࠊ㎰Ꮫࠊ⏕ែࠊ⎔ቃ࡜ࡢ㛵㐃ࢆㄪ࡭ࠊ㑇㊧ฟᅵグ㘓࡜ྜࢃࡏ࡚᧿ᩥ᫬௦ࡢṔྐࢆ⪃ᐹࡍࡿࡓࡵࠊ᱂ᇵ✀࢔࣡࡜࢟ࣅࡢ᪥ᮏ⣔⤫ ࢧࣥࣉࣝࡢ᱂ᇵ࡟ ᐊࢆ฼⏝ࡋࡓࠋලయⓗෆᐜࡣ
௨ୗࡢ㏻ࡾࠋ
᱂ᇵ✀࢔࣡  ⣔⤫ࡢ⫱ⱑࠊฟ✑㸸ࡑࢀࡒࢀࡢⴥ࠿
ࡽ '1$ ᢳฟ㸦Ѝ5$'VHT ゎᯒእὀ㸧ࠊ᰿࠿ࡽᰁⰍయ
ほᐹ᱂ᇵ✀࢟ࣅ  ⣔⤫ࡢ⫱ⱑࠊฟ✑㸸ࡑࢀࡒࢀࡢⴥ࠿
ࡽ '1$ ᢳฟ㸦Ѝ5$'VHT ゎᯒእὀ㸧ࠊ᰿࠿ࡽᰁⰍయほᐹ࢔࣡㏆⦕㔝⏕✀  ✀ࡢ᱂ᇵ ㄽᩥ 
Satomura, K., Osada, N., Endo, T. (2019) Achiasmy
and sex chromosome evolution. Ecological Genetics
and Genomics 13: 100046.
Ꮫ఍Ⓨ⾲ 
㔛ᮧ࿴ᾈ㸪㛗⏣┤ᶞ㸪㐲⸨ಇᚨ㸸Compensatory backmutation in mammalian genome. Society of Molecular
Biology and Evolution 2019,  ᖺ  ᭶  ᪥̺ ᪥
Manchester ᱂ᇵ✀ࣄࣙ࢘ࢱࣥࡢ㉳※࡜ఏ᧛⤒㊰ゎ᫂ࡢศᏊ㔛ᮧ࿴ᾈ㸸᱂ᇵ᳜≀࢔࣡ࠊ࢟ࣅ࡜㏆⦕㔝⏕✀㛫ࡢ⣔⤫ゎᯒࡢࡓࡵࠊ࢔ࢪ࢔ࠊ࣮ࣚࣟࢵࣃࠊ࢔ࣇࣜ࢝ࠊ
࢔࣓ࣜ࢝ࡢ᱂ᇵ✀࡜㔝⏕✀㸦/DJHQDULDDE\VVLQLFD 㑇ఏᏊὶືࡢṔྐࡢ᥎ᐃ㸬➨㸮ᅇ㐍໬Ꮫⱝᡭࡢ఍㸪− 26 −

 ᖺ  ᭶  ᪥㸪໭ᾏ㐨኱Ꮫ㸦ᮐᖠᕷ㸧㔛ᮧ࿴ᾈ㸪㛗⏣┤ᶞ㸪㐲⸨ಇᚨ㸸Compensatory backmutation in mammalian genome. ➨  ᅇ᪥ᮏ㐍໬Ꮫ఍㸪 ᖺ  ᭶  ᪥̺ ᪥㸪໭ᾏ㐨኱Ꮫ㸦ᮐᖠᕷ㸧
Dai Watabe, Hiroshi Yuasa, Naoki Osada, Toshinori
Endo
Molecular analysis for origin and propagation route of
the bottle gourd (Lagenaria siceraria) ➨  ᅇ᪥ᮏ㐍໬Ꮫ఍㸪 ᖺ  ᭶  ᪥̺ ᪥㸪໭ᾏ㐨኱Ꮫ㸦ᮐᖠᕷ㸧㔛ᮧ࿴ᾈ㸪㛗⏣┤ᶞ㸪㐲⸨ಇᚨ㸸့ங㢮ࡢ㑇ఏᏊ࡟࠾ࡅࡿከ㔜⨨᥮࡟ᑐࡍࡿ⮬↛㑅ᢥ㸬➨  ᅇ᪥ᮏ㐍໬Ꮫ఍㸪 ᖺ  ᭶  ᪥̺ ᪥㸪⚟஭኱Ꮫ㸦⚟஭ᕷ㸧㔛ᮧ࿴ᾈ㸪㛗⏣┤ᶞ㸪㐲⸨ಇᚨ㸸㞧✐࢔࣡࡜࢟ࣅ
ࡢ㑇ఏⓗከᵝᛶ㸬➨  ᅇ࣏ࣖࢿࢩ࢔ࢤࣀ࣒ࡃ࡟࠺
ࡳ࣑࣮ࢸ࢕ࣥࢢ㸪 ᖺ  ᭶  ᪥̺ ᪥㸪ῐ㊰ᓥክ⯙ྎᅜ㝿఍㆟ሙ㸦ῐ㊰ᕷ㸧㟁Ꮚ⛉Ꮫ◊✲ᡤ㝃ᒓ♫఍๰㐀ᩘᏛ◊✲ࢭࣥࢱ࣮ศ㔝」㞧⣔ᩘ⌮◊✲ศ㟷἟ ோᚿ
↓⬨᳝ື≀ࡢ⚄⤒⣔ࡣ㸪⬨᳝ື≀࡟ẚ࡭࡚ᑠつᶍ࡛࠶ࡿࡀ㸪⾜ືࡢከᵝᛶࡣ⬨᳝ື≀࡟ࡣຎࡽ࡞
࠸㸬ᡃࠎ㸪ࣄࢺࡢ⬻ࡢാࡁࢆ⌮ゎࡍࡿࡓࡵ࡟ࡣ㸪ᡃࠎ࡜ࡣ␗࡞ࡿ㐍໬ࢆࡓ࡝ࡾ࡞ࡀࡽࡶ㸪ከᵝ࡞⾜ືࢆⓎ⌧ࡍࡿ↓⬨᳝ືࡢ⚄⤒⣔ࡢാࡁࢆ⌮ゎࡍࡿࡇ࡜ࡀᚲ㡲࡛࠶ࡿ㸬ࡲࡓ㸪ᡃࠎࡣ㸪㧗ᗘ࡞ィ⟬ฎ⌮⬟ຊࢆഛ࠼ࡓィ⟬ᶵࢆᡭ࡟ධࢀࡓࡀ㸪ࣟ࣎ࢵࢺࡢࡼ࠺࡞ேᕤ≀ࡣ㸪࠸ࡲࡔ࡟ண ࡀᅔ㞴࡞↓㝈ᐃ࡞⎔ቃࢆ㉮◚ࡍࡿࡇ࡜ࡣ㠀ᖖ࡟ᅔ㞴࡛࠶ࡿ㸬ࣟ࣎ࢵࢺࡣ㸪࿘ࡾࡢ⎔ቃࢆほ ࡋ㸪ࡑࡢ⤖ᯝ࡟ᛂࡌ࡚
ືసฟຊࢆỴࡵࡿࡓࡵ࡛㸪ィ 㝈⏺ࢆ㉸࠼ࡓ⎔ቃୗ࡛ࡣືస࡛ࡁ࡞࠸࠿ࡽ࡛࠶ࡿ㸬୍᪉㸪ື≀ࡣ㸪↓㝈ᐃ࡞⎔ቃࡢ୰࡛ࡶ㐺ᛂⓗ࡟᣺ࡿ⯙ࡗ࡚࠸ࡿ㸬᪤▱⎔ቃࡢ୰࡛ࡋ࠿ேᕤ≀ࢆไᚚࡍࡿ᪉ἲࡋ࠿ᣢ
ࡕྜࢃࡏ࡚࠸࡞࠸ᡃࠎ࡟࡜ࡗ࡚ࣇ࣮࣒ࣞၥ㢟࡟ᑐฎࡍࡿ࡟ࡣఱࡽ࠿ࡢᡭᮏࡀᚲせ࡛࠶ࡾ㸪ࡑࢀࡀ⏕≀࡛࠶ࡿ㸬ࡲࡓ㸪ேᕤ≀࡜ື≀ࢆẚ㍑ࡍࡿࡇ࡜࡛㸪ື≀ࡢ㐺ᛂⓗ࡞ᶵ⬟ࡢ⌮ゎࢆ῝ࡵࡿࡇ࡜ࡀ࡛ࡁࡿ㸬᭦࡟ࡑࡇ࠿ࡽ᪂ወ࡞ேᕤ≀ࡢไᚚἲࡢᥦ᱌ࢆ┠ᣦࡋ࡚࠸ࡿ㸬᪻⹸ࡢࢥ࢜ࣟࢠ(G. bimaculatus)ࡸከ㊊㢮ࡢ࣒࢜࢜࢝ࢹ࣒࢝ࢹ(S. rubiginosus㸪S. subspinipes mutilans)ࢆ⏝࠸࡚㸪Ṍ⾜ࡢㄏⓎ࡟㛵ࢃࡿ୰ᯡ⚄⤒⣔ࡢാࡁ࡟ࡘ࠸࡚ㄪ࡭ࡓ㸬Ṍ⾜ࡣ㸪ྛయ⠇ࡢ௜ᒓ⫥ࢆ༠ㄪⓗ࡟ື࠿ࡍࡇ࡜࡛ᐇ⌧ࡉࢀ࡚࠸ࡿ㸬⬻࠿ࡽࡢୗ㝆ᛶࡢಙྕࡸྛయ⠇࡛ࡢឤぬࣇ࢕࣮ࢻࣂࢵࢡࡀ࡝ࡢ
ࡼ࠺࡟Ṍ⬮ࡢືࡁࢆไᚚࡋ࡚࠸ࡿࡢ࠿ࢆㄪ࡭ࡓ㸬⾜ື⏕⌮Ꮫᐇ㦂ཬࡧࣅࢹ࢜ࢺࣛࢵ࢟ࣥࢢࢆ౑ࡗࡓ
ゎᯒ࠿ࡽ㸪᪻⹸࡛ࡣ㸪ᚋ⬻࠿ࡽࡢୗ㝆ᛶࡢಙྕ࡟
ࡼࡾࣜࢬ࣑ࢵࢡ࡞Ṍᐜࣃࢱࣥࡀ⏕ᡂࡉࢀࡿࡇ࡜ࡀ
ࢃ࠿ࡗࡓ㸬୍᪉㸪࣒࢝ࢹ࡛ࡣ㸪Ṍ⾜ࡢㄏⓎࡸࣜࢬ࣒⏕ᡂ࡟࡜ࡗ࡚᪻⹸࡯࡝⬻ࡢാࡁࡀ኱ࡁࡃࡣ࡞࠸
ࡇ࡜ࡀࢃ࠿ࡗࡓ㸬ࡲࡓ㸪⎔ቃ࡜㌟య࡜⚄⤒⣔ࡢ┦஫స⏝࠿ࡽ⏕ࡌࡿ㐺ᛂᶵ⬟ࡢⓎ⌧࣓࢝ࢽࢬ࣒࡟ࡘ
࠸࡚⪃ᐹࡋ㸪㐺ᛂⓗ࡞᣺ࡿ⯙࠸ࡀ๰Ⓨࡉࢀࡿタィ࡜ࡑࡢไᚚᵓ㐀ࡢ⌮ゎࡀ῝ࡲࡗࡓ㸬࢔ࢠࢺ࢔ࣜ(O.
kuroiwae)࡛ࡣ㸪➽㦵᱁⣔ࡢᶵᵓ࡜㐠ືไᚚ࡟ࡘ࠸
࡚X⥺࢖࣓࣮ࢪࣥࢢἲࢆ⏝࠸࡚ㄪ࡭ࡓ㸬ࡲࡓ㸪኱㢡ࢆື࠿ࡍෆ㌿➽ࡸእ㌿➽ࡢ≧ែ࡟ࡘ࠸࡚X⥺⧄⥔ᅇᢡࢆ౑ࡗࡓ᪉ἲ࡛ㄪ࡭ࡓ㸬ࡑࡢ⤖ᯝ㸪㦵᱁➽ࡢືస࡜㸪㦵᱁ࡢᙎᛶኚᙧࢆ฼⏝ࡋࡓ㧗㏿㐠ືࡢⓎ⏕࣓࢝ࢽࢬ࣒ࡢ⌮ゎࡀ῝ࡲࡗࡓ㸬࢜࢜ࢡࣔࣄࢺࢹ
(Ophiarachna incrassate)࡜ࢳࣅࢡࣔࣄࢺࢹ (Ophiactis
brachyaspis)ࢆ⏝࠸࡚㸪㌟యᵓ㐀ࡢኚ໬࡜ࣜࢬ࣑ࢵ
ࢡ࡞㐠ືࣃࢱࣥࡢ⏕ᡂ࣓࢝ࢽࢬ࣒࡟ࡘ࠸࡚ㄪ࡭ࡓ㸬ࢡࣔࣄࢺࢹࡢከࡃࡣ㸪㸳ᮏࡢ⭎ࢆᣢࡘࡀ㸪᫬ࠎ㸲ᮏ࠿ࡽ㸵ᮏࡢ⭎ࡢᮏᩘࡀ␗࡞ࡿಶయࡀᚓࡽࢀࡿ㸬ࡇࢀࡽࡢಶయᕪࢆ฼⏝ࡋ࡚㸪┙࡛ぢࡽࢀࡿ࣏ࣥࣆ
ࣥࢢࡸ⭎ࢆ౑ࡗࡓࣟࢥ࣮ࣔࢩࣙࣥᵝᘧ࡜㌟యᵓ㐀ࡢ㛵ಀࢆㄪ࡭ࡓ㸬㐠ືィ ࡢ⤖ᯝ࡟ᇶ࡙࠸࡚ᩘ⌮ࣔࢹࣜࢆᵓ⠏ࡋ࡚⪃ᐹࡋࡓ⤖ᯝ㸪㌟యࡢᵓ㐀࡜⏕ᡂࡉࢀࡿࣜࢬ࣑ࢵࢡ࡞㐠ືࣃࢱࣥࡢ⏕ᡂ࡟ࡘ࠸࡚ࡢ⌮ゎࡀ῝ࡲࡗࡓ㸬Ꮫ⾡ㄽᩥ
Y. Sugimoto, K. Naniwa, H. Aonuma and K. Osuka:“Microinjection support system for small biologicalsubject”, HardwareX (2020)
H. Aonuma, M. Mezheritskiy, B. Boldyshev, Y. Totani,
D. Vorontsov, Z. S. Igor, E. Ito and D. Varvara: “Therole of serotonin in the influence of intense locomotion
on the behavior under uncertainty in the mollusk
Lymnaea stagnalis”, Frontiers in Physiology, 11: 221–(2020)
T. Kano, K. Daichi, T. Ono, H. Aonuma and A.
Ishiguro: “Flexible coordination of flexible limbs:
Decentralized control scheme for inter- and intra-limb
coordination in brittle stars' locomotion”, Frontiers in
Neurorobotics, (13): 104– (2019)
K. Yasui, T. Kano, E. M. Standen, H. Aonuma, A.
Ijspeert and A. Ishiguro: “Decoding the essential
interplay between central and peripheral control in
adaptive locomotion of amphibious centipedes”,
Scientific Reports, 9: 18288– (2019)
D. Wakita, K. Kagaya and H. Aonuma: “A generalmodel of locomotion of brittle stars with a variable− 27 −

number of arms”, Journal of the Royal SocietyInterface, 17(162) (2019)
T. Kano, D. Kanauchi, H. Aonuma, C. G. Elizabeth and
A. Ishiguro: “Decentralized control mechanism fordetermination of moving direction in brittle stars withpenta-radially symmetric body”, Frontiers in
Neurorobotics, (13): 66– (2019)
D. Wakita, Y. Hayase and H. Aonuma: “Different
synchrony in rhythmic movement caused bymorphological difference between five- and six-armed
brittle stars”, Scientific Reports, (9): 8298– (2019)⥲ㄝ࣭ゎㄝ࣭ホㄽ➼ᑠᯘ ுࠊ㟷἟ ோᚿࠊᒸ⏣ ⨾ᬛ⏨ࠊ▼㯮 ❶ኵࠊ኱㡲㈡ බ୍ࠊ▼ᕝ ᑗே: ࠕࠕ⎔ቃࢆ཭࡜ࡍࡿࠖࢆ
Ꮫၥࡋࡼ࠺ࠖࠊࢩࢫࢸ࣒/ไᚚ/᝟ሗ, ࠕ⎔ቃࢆ཭࡜ࡍࡿไᚚἲࡢ๰ᡂࠖ≉㞟ྕࠊ63(6): 246–253 (2019)

Totani, M. Mazheritskiy, D. Vorontsov, E. Ito and T.
Dyakonova : “Interplay of past and present behavioral
experiences in the molluscan CNS”, 1st Symposium on
Invertebrate Neuroscience, Balaton Limnological
Institute, Tihany, Hungary (2019 ᖺ 8 ᭶)
Y. Totani*, H. Aonuma, J. Nakai and E. Ito : “Effect of
5-HT and insulin on leaning and memory”, 1stSymposium on Invertebrate Neuroscience, Balaton
Limnological Institute, Tihany, Hungary (2019 ᖺ 8 ᭶)ᯇ⏣ ᮅ㝧*ࠊ㟷἟ ோᚿࠊ㔠Ꮚ ಇ୍ : ࠕ࢔ࢠࢺ࢔
ࣜࡢ኱㢡ࡢ㉸㧗㏿㐠ືゎᯒࡢࡓࡵࡢ⏬ീィ ᡭἲࠖࠊ2019 ᖺᗘ ⢭ᐦᕤᏛ఍ ໭ᾏ㐨ᨭ㒊 Ꮫ⾡ㅮ₇఍ࠊภ㤋ᕤᴗ㧗➼ᑓ㛛ᏛᰯࠊJapan (2019 ᖺ 8 ᭶)

K. Naniwa*, Y. Sugimoto, K. Osuka and H. Aonuma :“Defecation initiates a stereotyped behavior in thecricket Gryllus bimaculatus”, The 9th International
Symposium on Adaptive Motion of Animals and㟷἟ ோᚿ: ࠕ ⏕ࡁ≀ࡀࡶࡘ㌟యᵓ㐀࡜㌟య㐠ືࠖࠊ Machines(AMAM2019), Lausanne, Swaziland (2019ᖺ 8 ᭶)
ࢩࢫࢸ࣒/ไᚚ/᝟ሗ, ࠕ⎔ቃࢆ཭࡜ࡍࡿไᚚἲࡢ๰
ᡂࠖ≉㞟ྕࠊ63(6): 223–228 (2019)㟷἟ ோᚿ* : ࠕMechanism underlying generating
ultra fast movement in insect ࠖࠊ 9th International
Ꮫ఍Ⓨ⾲Congress on Industrial and Applied Mathematics㟷἟ ோᚿ* : ࠕNeurobiology and biomechanics of(ICIAM 2019)ࠊValenciaࠊSpain (2019 ᖺ 7 ᭶)
ultra fast movement in the trap-jaw antࠖࠊThe 3rdᯇ⏣ ᮅ㝧*ࠊ㟷἟ ோᚿࠊ㔠Ꮚ ಇ୍ : ࠕ࢔ࢠࢺ࢔
International Symposium on Swarm Behavior andBio-Inspired Robotics (SWARM 2019)ࠊOkinawaࠊࣜࡢ኱㢡ࡢ㉸㧗㏿㐠ືィ ࡢࡓࡵࡢᅇ㌿↷ྜἲࠖࠊ
SSII2019(The 25th Symposium on Sensing via ImageJapan (2019 ᖺ 11 ᭶)
Information)ࠊࣃࢩࣇ࢕ࢥᶓ὾࢔ࢿࢵࢡࢫ࣮࣍ࣝࠊ
A. Matsuda*, H. Aonuma and S. Kaneko : “A structural
Japan (2019 ᖺ 6 ᭶)analysis based on kinetic model of trap-jaw in
Odontomachus”, AISM2019 (The 7th Asia International
Symposium on Mechatronics), Hangzhou dianzi
University, China (2019 ᖺ 9 ᭶)㟷἟ ோᚿ* : ࠕX ⥺࣐࢖ࢡࣟ࢖࣓࣮ࢪࣥࢢ࠿ࡽษ
ࡾᣅࡃ᪻⹸ࡢ㐠ືไᚚ࣓࢝ࢽࢬ࣒ࠖ
ࠊ➨ 89 ᅇ᪥ᮏື≀Ꮫ఍ࢩ࣏ࣥࢪ࣒࢘ࠕࢩࣥࢡࣟࢺࣟࣥᨺᑕග X⥺ࡣື≀Ꮫ࡝࠺ᙺ❧ࡘ࠿㸽 −SPring-8 ඛ➃฼⏝ᢏ⾡࣮࣡ࢡࢩࣙࢵࣉ−ࠖࠊ኱㜰ᕷ❧኱ᏛࠊJapan (2019ᖺ 9 ᭶)
Y. Totani*, H. Aonuma, J. Nakai and E. Ito : “Insulin
rescues memory impairment caused by the increased
5-HT content in the central nerves system in Lymnaea”,
The 10th IBRO World Congress of Neuroscience,
Degu, Korea (the Democratic People's Republic of)(2019 ᖺ 9 ᭶)
D. Wakita* and H. Aonuma : “Attempt to identify bodystructure generating a balloon-like rhythmic movementin the green brittle star”, 1st Symposium on
Invertebrate Neuroscience, Balaton Limnological
Institute, Tihany, Hungary (2019 ᖺ 8 ᭶)
V. Dyakonova*, G. Sultanachmetov, H. Aonuma, Y.

໭᪉⏕≀ᅪࣇ࢕࣮ࣝࢻ⛉Ꮫࢭࣥࢱ࣮
⏕≀ከᵝᛶ㡿ᇦ ᾏ⏘⸴㢮㐺ᛂᶵ⬟ศ㔝ᅄࢶ಴ ඾⁠㸦ᾏỈ฼⏝㸧Ⓨ⾲ㄽᩥ
Starko, S., Soto, M., Darby, H., Demes, K., Kawai, H.,
Yotsukura, N., Lindstrom, S., Keeling, P., Graham, S.,
and Marton, P. (2019) A comprehensive kelp
phylogeny sheds light on the evolution of an
ecosystem. Molecular Phylogenetics and Evolution
136: 138-150.
Zhang, J., Wang, X., Yao, J., Yotsukura, N, and Duan,
D. (2019) Screening of polymorphic microsatellites
and their application for Saccharina angustata andSaccharina longissima population genetic analysis.
Journal of Applied Phycology 31: 3295-3301.
Kawai, T., Galanin, D., Druehl, L., and Yotsukura, N.
(2019) Information of the Sakhalin kelp Saccharina
lattisima in northern Hokkaido, Japan and southern
Sakhalin, far-east Russia. Algal Resources 12: 21-26.
Kawai, T., Klochkova, N., Matsushita, N., Izergin, L.,− 28 −

and Yotsukura, N. (2019) Potential resources of
Laminaria appressirhiza for kelp fisheries in Magadan,
far-east Russia. Algal Resources 12: 55-60.
Yotsukura, N., Maeda, T., and Kawai, T. (2019) New
record of the distribution of Saccharina japonica(Laminariales, Phaeophyceae) in Hokkaido, Japan.
Algal Resources 12: 67-72.
Sudo, K., Watanabe, K., Yotsukura, N., and Nakaoka,
M. (2020) Predictions of kelp distribution shifts along
the northern coast of Japan. Ecological Research 35:
47-60.
Ꮫ఍Ⓨ⾲
Norishige Yotsukura: Current status and assignmentsof seaweed cultivation and breeding in Japan. 23rd
International Seaweed Symposium, April 29 2019,
International Convention Center, Jeju, Korea.

⥲ྜ༤≀㤋◊✲㒊 ㈨ᩱᇶ♏◊✲⣔㜿㒊 ๛ྐ㸦ᾏỈ฼⏝㸧ㄽᩥIshii, T., Shinjo, Y., Miyagi, M., Matsuura, H., Abe, T.,
Kikuchi, N. and Suzuki, M. (2019) Investigation of
Insect Repellent Activity of Cyclocolorenone Obtained
from the Red Alga Laurencia intricata. Records of
Natural Products 13(1): 81-84.
DOI: https://doi.org/10.25135/rnp.66.18.02.221
Kawai T., Klochkova, N. G., Kogame, K., Abe, T.,
Galanin, D. and Yotsukura, N. (2019) Marine Flora in
Northern Hokkaido and Southern Sakhalin along theCoast of the Sea of Japan. Rishiri Studies 38: 95-98.
Ishii, T., Miyagi, M., Shinjo, Y., Minamida, Y.,
Matsuura, H., Abe, T., Kikuchi, N. and Suzuki, M.
(2019) Two new brominated C15-acetogenins from thered alga Laurencia japonensis. Natural ProductResearch. Published online.
DOI: https://doi.org/10.1080/14786419.2019.1590712− 29 −

すᲷ㑇ఏᏊᐇ㦂ඹ
ඹྠ฼⏝㒊㛛
ື≀ᰁⰍయඹ
ඹྠ฼⏝㒊㛛

− 31 −㑇 ఏᏊᐇ㦂ඹྠ฼⏝㒊㛛㛛  ᙜ㒊㛛࡛ࡣࠊ㑇ఏᏊ⤌ࡳ᥮࠼ᐇ㦂࡟ᚲせ࡞ࢡ࣮ࣜࣥ࣋ࣥࢳࡸᏳ඲࢟ࣕࣅࢿࢵࢺࠊ኱
ᆺ࣮࢜ࢺࢡ࣮ࣞࣈ➼ࡢ≉Ṧタഛࢆഛ࠼࡚࠾ࡾࠊ⥅⥆ⓗ࡟ά⏝ࡉࢀ࡚࠸ࡲࡍࠋ㑇ఏᏊ⤌᥮࠼ᐇ㦂ࡀ୍⯡໬ࡋࡓࡇ࡜࠿ࡽ≉Ṧタഛ฼⏝௨እࡢ฼⏝⪅ࡣῶᑡࡋࡲࡋࡓࡀࠊ◊✲㐣⛬୍࡛ᐃᮇ㛫୍᫬ⓗ࡟ᚲせ࡟࡞ࡿࡶࡢࡢ◊✲ᐊ࡛‽ഛࡍࡿ࡟ࡣ㈇ᢸ࡜࡞ࡿࡼ࠺࡞ᶵჾ
ࡸࠊ◊✲ᐊࡢ❧ࡕୖࡆ᫬࡟ᶵჾࡀᩚ࠺ࡲ࡛ࡢᮇ㛫ࠊࡶࡋࡃࡣᨾ㞀ᶵჾࡢ⿵ಟ᏶஢ࡲ࡛
࡟฼⏝࡛ࡁࡿྛ✀㑇ఏᏊゎᯒᶵჾࢆ඲Ꮫ࡟ᥦ౪ࡋ࡚࠸ࡲࡍࠋࡋ࠿ࡋࠊ඲యⓗ࡟タഛ➼ࡢ⪁ᮙ໬ࡀ㐍ࡳ㸪ࡉࡽ࡟ᖹᡂ  ᖺ  ᭶࡟ࡣ኱つᶍ࡞₃Ỉ஦ᨾࡀⓎ⏕ࡋ࡚࠾ࡾࠊࡑࡢᑐ
⟇ࡀᛴົ࡛ࡍࠋ ᖹᡂ  ᖺ  ᭶࡟㉳ࡁࡓᮾ᪥ᮏ኱㟈⅏࡟ࡼࡾࠊ◊✲ᶵ㛵࡛ከࡃࡢ⏕≀ᮦᩱ࣭㑇ఏ㈨※ࡀኻࢃࢀ◊✲ࡢ⥅⥆࡟ᨭ㞀ࢆࡁࡓࡋࡲࡋࡓࠋ෌ࡧࡇࡢࡼ࠺࡞ࡇ࡜ࡀ㉳ࡇࡿ࡜ᡃࡀᅜࡢ
ᅜ㝿ⓗ➇தຊ࡟ࡶᝏᙳ㡪ࢆ୚࠼࠿ࡡ࡞࠸࡜ࡢ༴᝹࠿ࡽࠊ᪥ᖖⓗ࡟◊✲⏝⏕≀㑇ఏ㈨※ࡢಖ⟶ࢆ⾜࠺ᩥ㒊⛉Ꮫ┬ࣉࣟࢪ࢙ࢡࢺࠕ኱Ꮫ㐃ᦠࣂ࢖࢜ࣂࢵࢡ࢔ࢵࣉࣉࣟࢪ࢙ࢡࢺ
㸦,%%3㸧ࠖࡀឡ▱┴ᒸᓮᕷࡢᇶ♏⏕≀Ꮫ◊✲ᡤࢆ୰᰾ᣐⅬ࡜ࡋ࡚㛤ጞࡉࢀࠊᙜࢭࣥࢱ࣮
ࡣ໭ᾏ㐨ᆅ༊ࡢࢧࢸࣛ࢖ࢺᣐⅬ࡜ࡋ࡚ࡇࡢࣉࣟࢪ࢙ࢡࢺ࡟ཧ⏬ࡋ࡚࠸ࡲࡍࠋື ≀ᰁⰍయඹྠ฼⏝㒊㛛㛛 ື≀ᰁⰍయඹྠ฼⏝㒊㛛࡛ࡣࠊ⣽⬊ᇵ㣴タഛ࡜ࡋ࡚ࠊࢡ࣮ࣜࣥ࣋ࣥࢳࠊ&2 ࢖࣮ࣥ࢟ࣗ࣋ࢱ࣮ࠊ㐲ᚰᶵ࡞࡝ࢆࠊࡲࡓ⣽⬊ಖᏑタഛ࡜ࡋ࡚ࡣࠊᑓ⏝ࡢΥࢹ࢕࣮ࣉࣇ࣮ࣜࢨ
࣮࠾ࡼࡧ኱ᆺᾮయ❅⣲෾⤖ಖᏑᐜჾࢆഛ࠼࡚࠸ࡲࡍࠋᙜ㒊㛛࡛ࡣࠊ⣔⤫ศ㢮Ꮫࠊ㐍໬Ꮫⓗ࡟฼⏝౯್ࡀ㧗࠸࡜ᛮࢃࢀࡿึ௦ᇵ㣴⣽⬊㢮㸸့ங㢮㸦 ┠  ⛉  ✀  ள✀㸧ࠊ㫽㢮㸦 ┠  ⛉  ✀㸧ࠊ∐⹸㢮㸦 ┠⛉✀㸧࡜ࠊⓎ⏕Ꮫࡸ⏕໬Ꮫࠊ⣽⬊㑇ఏᏛ࡞࡝ࡢᐇ㦂࡟⏝࠸ࡽࢀࡿྛ✀ᇵ㣴⣽⬊ᰴࢆ෾⤖ಖᣢࡋ࡚࠾ࡾࠊᚲせ࡟ᛂࡌ࡚ෆእࡢ◊✲⪅࡬ࡢศ୚ࢆ⾜ࡗ࡚࠸ࡲࡍࠋࡇࢀࡽࡢ⣽⬊ࡢ࠺ࡕከࡃࡢࡶࡢࡣᪧ⌮Ꮫ㒊㝃ᒓື≀ᰁⰍయ◊✲᪋タ࡟࠾࠸࡚ᶞ❧ࠊ࠶ࡿ࠸ࡣ཰㞟ࡉࢀࡓࡶࡢ࡛࠶ࡾࠊྠ᪋タࡢ⤫ᗫྜᚋࡣࠊ୺࡟す⏣༓㭯Ꮚඛ⏕ࡢࡈດຊ࡟ࡼࡗ࡚⥔ᣢࡉࢀ࡚ࡁࡓࡶࡢ࡛ࡍࠋࡇࡢࡼ࠺࡞Ṕྐⓗ࡟㈗㔜࡞⣽⬊ࢆ௒ᚋࡶ౪୚ྍ⬟࡞≧ែ࡛⥔ᣢࡋ⥆ࡅࡿ࡜࡜ࡶ࡟ࠊᏛෆ࡛ࡢඛ➃ⓗ࡞◊✲࡟⏝࠸ࡽࢀࡓྛ✀ᇵ㣴⣽⬊㢮ࡸ⏕≀ヨᩱࢆᆅ㐨࡟཰㞟ࠊಖᏑࡋ࡚࠸ࡃࡇ࡜ࡶ௒ᚋࡢㄢ
㢟࡛ࡍࠋ ᖺ  ᭶ࡢ໭ᾏ㐨⫹᣺ᮾ㒊ᆅ㟈࡟క࠺㟁※႙ኻ࡛ࡣࠊᏛෆࡢከࡃࡢ◊✲ᐊ
࡛㈗㔜࡞ヨᩱࡀኻࢃࢀࡲࡋࡓࠋ⏕యヨᩱࡢಖᏑ࡜౪⤥࡟㛵ࢃࡗ࡚ࡁࡓᙜ㒊㛛࡛ࡣࠊ௒ᖺᗘ࡜᮶ᖺᗘ࡟ࢃࡓࡗ࡚ணᐃࡉࢀ࡚࠸ࡿࢭࣥࢱ࣮ᨵ⤌஦ᴗ࡟࠾࠸࡚ࠊ⥭ᛴ᫬࡟࠾ࡅࡿ
⮬ᐙⓎ㟁ᶵ⬟ࢆഛ࠼ࡓࢹ࢕࣮ࣉࣇ࣮ࣜࢨ࣮ᐊࡢタ⨨ࢆணᐃࡋ࡚࠸ࡲࡍࠋᖹᖖ᫬࡟࠾ࡅ
ࡿヨᩱಖ⟶࡟㛵ࡍࡿࣂࢵࢡ࢔ࢵࣉሙᡤࡢᥦ౪ࡸࠊ㟁※႙ኻ᫬࡟࠾ࡅࡿヨᩱ㑊㞴ሙᡤࡢ☜ಖ࡞࡝ࢆ㏻ࡌ࡚ࠊ⏕≀Ꮫⓗヨᩱಖ඲ࡢሙࢆᥦ౪ࡋࡓ࠸࡜⪃࠼࡚࠸ࡲࡍࠋ௧ ࿴ඖᖺᗘ 㑇ఏᏊᐇ㦂ඹྠ฼⏝㒊㛛࣭ື≀ᰁⰍయ◊✲㒊㛛 ಖ ᏲႠ⧋ࣜࢫࢺ
࣭ᐃᮇΎᤲ㸦ẖ᭶㸧࣭௧࿴ඖᖺ 9 ᭶  ඲Ꮫ೵㟁࡟క࠺௬タືຊタഛᕤ஦− 32 −

ඹྠ฼⏝ᶵჾ㻌䞉㻌タഛタഛ䛚䜘䜃ᶵჾྡ

䝯䞊䜹䞊ྡ䞉ᆺ␒➼ᇵ㣴ᐊ㻌䠄㻝㻜䟝䠅ᇵ㣴ᐊ㻌䠄㻝㻠䟝䠅㻼㻝ᐇ㦂ᐊ㻼㻞ᐇ㦂ᐊ㻌䠄Ᏻ඲䜻䝱䝡䝛䝑䝖䠅పᐇ㦂ᐊ㻌䠄㻠䉝䠅

⣽⬊ಖᏑᐊᾮయ❅⣲ᘧ෾⤖ಖᏑᐜჾኴ㝧᪥㓟㻌䞉㻰㻾㻙㻝㻜㻜㻜㻾㻵㻌䞉⺯ග䝞䜲䜸䜲䝯䞊䝆䝱䞊㻲㼁㻶㻵㻌㻲㻵㻸㻹㻌䞉㻲㻸㻭㻙㻣㻜㻜㻜

໬ᏛⓎග᧜ᙳ⿦⨨㻭㼀㼀㻻㻌䞉㻱㼆㻙㻯㼍㼜㼠㼡㼞㼑䝀䝹᧜ᙳ⿦⨨

㻭㼀㼀㻻㻌䞉㻭㻱㻙㻢㻥㻟㻞䝀䝹᧜ᙳ⿦⨨

㻭㼀㼀㻻㻌䞉㻭㻱㻙㻢㻥㻞㻜㑇ఏᏊᑟධ⿦⨨㻌䠄䜶䝺䜽䝖䝻䝫䝺䞊䝍䞊䠅㻮㼕㼛㻙㻾㼍㼐㻌䞉㻳㼑㼚㼑㻌㻼㼡㼘㼟㼑㼞㑇ఏᏊᑟධ⿦⨨㻌䠄䜶䝺䜽䝖䝻䝫䝺䞊䝍䞊䠅㻿㻴㻵㻹㻭㻰㼆㼁㻌䞉㻳㼀㻱㑇ఏᏊᑟධ⿦⨨㻌䠄㑇ఏᏊ㖠䠅㻮㼕㼛㻙㻾㼍㼐㻌䞉㻴㼑㼘㼕㼛㼟㻌㻳㼑㼚㼑㻌㻳㼡㼚䝹䝭䝜䝯䞊䝍䞊

㻭㼀㼀㻻㻌䞉㻭㻮㻙㻞㻞㻜㻜᳜≀ᇵ㣴䝏䝱䞁䝞䞊㻌䠄䝁䜲䝖䝖䝻䞁䠅䠄㻟ྎ䠅㻷㻻㻵㼀㻻㻌䞉㻴㻺㻸㻙㻝㻜㻭䠄㻞ྎ䠅㻘㻌㻴㻺㻮㻙㻝㻜㻭䠄㻝ྎ䠅᳜≀䜲䞁䜻䝳䝧䞊䝍䞊䠄ேᕤẼ㇟ჾ䠅㼀㻻㻹㼅㻌䞉㻯㻸㻱㻙㻟㻜㻡኱ᆺᜏ᣺䛸䛖ᇵ㣴ᶵ㻌䠄䝞䜲䜸䝅䜵䞊䜹䞊䠅㼀㻭㻵㼀㻱㻯㻌䞉㻮㻾㻙㻟㻜㻜㻸㻲኱ᆺᜏ᣺䛸䛖ᇵ㣴ᶵ㻌䠄䝞䜲䜸䝅䜵䞊䜹䞊䠅㼀㻭㻵㼀㻱㻯㻌䞉㻮㻾㻙㻝㻤㻜㻸㻲ᑠᆺᜏ᣺䛸䛖ᇵ㣴ᶵ㻌䠄䝞䜲䜸䝅䜵䞊䜹䞊䠅㻌䠄㻞ྎ䠅㼀㻭㻵㼀㻱㻯㻌䞉㻮㻾㻙㻞㻟㻲㻼ᑠᆺ㉸㐲ᚰᶵ

㻮㼑㼏㼗㼙㼍㼚㻌䞉㼀㻸㻙㻝㻜㻜ᑠᆺ㉸㐲ᚰᶵ

㻴㼕㼠㼍㼏㼔㼕㻌䞉㻴㼕㼙㼍㼏㻌㻯㻿㻝㻜㻜㉸㐲ᚰᶵ㻌䠄㻞ྎ䠅㻴㼕㼠㼍㼏㼔㼕㻌䞉㻡㻡㻼㻙㻣㻞㧗㏿෭༷㐲ᚰᶵ㻌䠄㻞ྎ䠅㼀㻻㻹㼅㻌䞉㻾㻿㻙㻝㻤㻵㼂䠄㻝ྎ䠅㻘㻌㻿㼡㼜㼞㼑㼙㼍㻞㻝䠄㻝ྎ䠅ᚤ㔞㧗㏿෭༷㐲ᚰᶵ㻌䠄㻡ྎ䠅㼀㻻㻹㼅㻌䞉㻹㻾㻙㻝㻡㻜㻘㻌㻹㻾㼄㻙㻝㻡㻜㻘㻌㻹㼄㻙㻝㻜㻜㻘㻌㻹㼄㻙㻝㻜㻣㻘㻌㻹㼄㻙㻟㻜㻣䠄ྛ㻝ྎ䠅㻼㻯㻾⿦⨨㻭㻿㼀㻱㻯㻌䞉㻼㻯㻣㻜㻝㻼㻯㻾⿦⨨㻭㻿㼀㻱㻯㻌䞉㻼㻯㻣㻜㻤㻼㻯㻾⿦⨨㼀㼍㼗㼍㼞㼍㻌䞉㼀㼔㼑㼞㼙㼍㼘㻌㻯㼥㼏㼘㼑㼞㻌㻰㼕㼏㼑㻌㼀㼛㼡㼏㼔ᐃ㔞㻼㻯㻾⿦⨨㼀㼍㼗㼍㼞㼍㻌䞉㼀㼔㼑㼞㼙㼍㼘㻌㻯㼥㼏㼘㼑㼞㻌㻰㼕㼏㼑㻌㻾㼑㼍㼘㻌㼀㼕㼙㼑㻌㻿㼥㼟㼠㼑㼙㻌䊡䝟䝹䝇䝣䜱䞊䝹䝗㟁ẼὋື⿦⨨㻮㼕㼛㻙㻾㼍㼐㻌䞉㻼㼡㼘㼟㼣㼍㼢㼑㻣㻢㻜䝤䝻䝑䝔䜱䞁䜾⿦⨨㻌䠄Ὃືᘧ䞉䝉䝭䝗䝷䜲ᘧ䠅䠄㻞ྎ䠅㻭㼀㼀㻻㻌䞉㻭㻱㻙㻢㻢㻣㻜㼁㼂䜽䝻䝇䝸䞁䜹䞊㻲㼡㼚㼍㼗㼛㼟㼔㼕㻌䞉㻲㻿㻙㻤㻜㻜ศගගᗘィ㻿㻴㻵㻹㻭㻰㼆㼁㻌䞉㼁㼂㻙㻝㻢㻜ศගගᗘィ㻮㼑㼏㼗㼙㼍㼚㻌䞉㻰㼁㻙㻢㻡ᚤ㔞ศගගᗘィ㼀㼔㼑㼞㼙㼛㻌㻿㼏㼕㼑㼚㼠㼕㼒㼕㼏㻌䞉㻺㼍㼚㼛㻰㼞㼛㼜㻌㻞㻜㻜㻜䠄ỈᖹẼὶᆺ䠅㻌䜽䝸䞊䞁䝧䞁䝏㻌䠄㻞ྎ䠅㻿㻴㻻㼃㻭㻌䞉㻿㻙㻝㻟㻜㻜䠄ỈᖹẼὶᆺ䠅㻌䜽䝸䞊䞁䝧䞁䝏㻴㼕㼠㼍㼏㼔㼕㻌䞉㻼㻯㻴㻙㻝㻟㻜㻟㻮㻿ᐇయ㢧ᚤ㙾㻻㼘㼥㼙㼜㼡㼟㻌䞉㻿㼆㻢㻝㉸㡢Ἴ◚○⿦⨨㼀㻻㻹㼅㻌䞉㼁㻰㻙㻞㻜㻝኱ᆺ䜸䞊䝖䜽䝺䞊䝤㼀㻻㻹㼅㻌䞉㻲㻸㻿㻙㻝㻜㻜㻜୰ᆺ䜸䞊䝖䜽䝺䞊䝤㼀㻻㻹㼅㻌䞉㻸㻿㼄㻙㻡㻜㻜ᑠᆺ䜸䞊䝖䜽䝺䞊䝤㼀㻻㻹㼅㻌䞉㻮㻿㻙㻞㻠㻡ᑠᆺ䜸䞊䝖䜽䝺䞊䝤㻿㻭㻺㼅㻻㻌䞉㻹㻸㻿㻙㻞㻠㻜㻜஝⇕⁛⳦ᶵ㻌䠄㻟ྎ䠅㼅㼍㼙㼍㼠㼛㻌䞉㻿㻷㻢㻜㻝䠄㻞ྎ䠅㻘㻌㻿㻳㻙㻢㻞䠄㻝ྎ䠅㉸ప㻿㻭㻺㼅㻻䞉㻹㻰㻲㻙㻟㻥㻞㻌㻘㻿㻭㻺㼅㻻䞉㻹㻰㻲㻙㻠㻥㻟㻌㻘㻌㻼㻴㻯䞉㻹㻰㻲㻙㻟㻥㻠㻙㻼㻶䠄㻞ྎ䠅෭෾ᗜ㻌䠄㻙㻤㻜䉝䠅䠄㻠ྎ䠅䝗䝷䝣䝖䝏䝱䞁䝞䞊㻰㻭㻸㼀㻻㻺㻌䞉㻰㻲㻙㻯䠄≉䠅ᰯṇ⏝ศ㖡ෆⶶᆺ㟁Ꮚኳ⛗㻭㻒㻰㻌䞉㻲㼆㻙㻞㻜㻜㻜㼕䝉䝹䝋䞊䝍䞊

㻮㼍㼥㻌㼎㼕㼛㼟㼏㼕㼑㼚㼏㼑㻌㻶㻿㻭㻹− 33 −

௧࿴ඖᖺᗘ䚷䝀䝜䝮䝎䜲䝘䝭䜽䝇◊✲䝉䞁䝍䞊䚷฼⏝⪅◊✲ㄢ㢟䠄㑇ఏᏊᐇ㦂ඹྠ฼⏝㒊㛛䞉ື≀ᰁⰍయඹྠ฼⏝㒊㛛䠅◊㻌㻌✲㻌㻌ㄢ㻌㻌㢟㻌㻌ྡᡤ㻌㻌ᒓ㒊㻌㻌㛛㻌㻌䞉㻌㻌ศ㻌㻌㔝㻌㻌➼

⫋㻌ྡ

Ặ㻌㻌ྡ

⌮Ꮫ◊✲㝔

໬Ꮫ䞉᭷ᶵ䞉⏕࿨໬Ꮫᩍ㻌ᤵᆏཱྀ㻌㻌࿴㟹

⌮Ꮫ◊✲㝔⏕≀⛉Ꮫ䞉ᙧែᶵ⬟Ꮫᩍ㻌ᤵຍ⸨㻌㻌ᩔஅ 㻌㻌䝅䝻䜲䝚䝘䝈䝘䛻䛚䛡䜛ᙧែᙧᡂ㛵㐃㑇ఏᏊ䛾ゎᯒ⌮Ꮫ◊✲㝔⏕≀⛉Ꮫ䞉⾜ື⚄⤒⏕≀Ꮫ

ᩍ㻌ᤵ

ỈἼ䚷ㄔ

⌮Ꮫ◊✲㝔

⏕≀⛉Ꮫ䞉⾜ື⚄⤒⏕≀Ꮫ෸ᩍᤵ໭⏣㻌㻌୍༤ 㻌㻌᪂䛯䛺⑓ែ䝰䝕䝹ື≀䛾సฟ䛸ཎᅉ㑇ఏᏊ䛾ྠᐃ⌮Ꮫ◊✲㝔⏕≀⛉Ꮫ䞉⾜ື⚄⤒⏕≀Ꮫ෸ᩍᤵ࿴ከ䚷࿴ᏹ 䚷㬆⚺㢮䜢⏝䛔䛯ⓎኌᏛ⩦䞉⏕ᡂ䛸䛭䛾⬻ෆศᏊᶵᵓ⌮Ꮫ◊✲㝔⏕≀⛉Ꮫ䞉⏕ṪⓎ⏕⏕≀Ꮫᩍ㻌ᤵ㯮ᒾ㻌㻌㯞㔛

⌮Ꮫ◊✲㝔⏕≀⛉Ꮫ䞉⏕ṪⓎ⏕⏕≀Ꮫᩍ㻌ᤵᒣୗ㻌㻌ṇව 㻌㻌⬨᳝ື≀䛻䛚䛡䜛⏕Ṫ⣽⬊ᙧᡂ䛾ไᚚᶵᵓ⌮Ꮫ◊✲㝔⏕≀⛉Ꮫ䞉⏕ṪⓎ⏕⏕≀Ꮫ

෸ᩍᤵ

ᮌᮧ㻌㻌ᩔ

㻌㻌့ங㢮䛾⏕Ṫ䛻䛛䛛䜟䜛䝀䝜䝮ᶵ⬟䛻㛵䛩䜛◊✲⌮Ꮫ◊✲㝔⏕≀⛉Ꮫ䞉⏕ṪⓎ⏕⏕≀Ꮫຓ㻌ᩍྜྷ⏣㻌㻌㑳ஓ

့ங㢮୙άᛶXᰁⰍయ䛾෌άᛶ໬ᶵᵓ䛾ゎᯒ⌮Ꮫ◊✲㝔⏕≀⛉Ꮫ䞉ከᵝᛶ⏕≀Ꮫᩍ㻌ᤵᑠட䚷୍ᘯ 䚷⸴㢮䛾⣔⤫㐍໬Ꮫ⌮Ꮫ◊✲㝔⏕≀⛉Ꮫ䞉ከᵝᛶ⏕≀Ꮫᩍ㻌ᤵቑ⏣㻌㻌㝯୍ 㻌㻌့ங㢮䛚䜘䜃㫽㢮䛾ศᏊ㐍໬䛸㑇ఏⓗከᵝᛶ䛻㛵䛩䜛◊✲ඛ➃⏕࿨⛉Ꮫ ⏕࿨ᶵ⬟⛉Ꮫ◊✲䞉⏕≀᝟ሗゎᯒ⛉Ꮫ◊✲
◊✲㝔

ᩍ㻌ᤵ

ฟᮧ㻌㻌ㄔ

㻌᝟ሗ⛉Ꮫ◊✲㝔 ⏕࿨ே㛫᝟ሗ⛉Ꮫ䞉㻌䝞䜲䜸䜲䞁䝣䜷䝬䝔䜱䜽䝇ᩍ㻌ᤵ㐲⸨㻌㻌ಇᚨ 㻌㻌䝠䝵䜴䝍䞁䛾ศᏊ⣔⤫ゎᯒ

⥲ྜ༤≀㤋

෸ᩍᤵ

Ụ⏣㻌㻌┿Ẏ 㻌㻌⌧⏕䛚䜘䜃㑇㊧ฟᅵ䛾ື≀㉁㈨ᩱ䛾ሷᇶ㓄ิ䛾Ỵᐃ◊✲㒊䞉㈨ᩱ㛤Ⓨ◊✲⣔௧࿴ඖᖺᗘ䚷฼⏝≧ἣᡤ㻌㻌ᒓ㻌㻌

฼㻌⏝㻌⪅㻌ᩘ኱Ꮫ㝔⌮Ꮫ◊✲㝔㻝㻝኱Ꮫ㝔ඛ➃⏕࿨⛉Ꮫ◊✲㝔㻝኱Ꮫ㝔᝟ሗ⛉Ꮫ◊✲㝔

㻝

⥲ྜ༤≀㤋

㻝

ྜ㻌㻌ィ㻌

㻝㻠

− 34 −⒴ᢚไ䝍䞁䝟䜽㉁p53䛚䜘䜃㛵㐃ᅉᏊ䛾ᵓ㐀ᶵ⬟┦㛵㻌㻌䝣䝍䝩䝅䝁䜸䝻䜼䛾Ꮫ⩦䛚䜘䜃ᛶỴᐃ䛾◊✲

XOᆺ䝖䝀䝛䝈䝭䛻䛚䛡䜛䝀䝜䝮ゎᯒ

㻌㻌⺮ⓑ㉁䛾❧యᵓ㐀ゎᯒ䛻㛵䛩䜛◊✲Мဇ‫إ‬ԓᴾᴾ
኱Ꮫ㝔⌮Ꮫ◊✲㝔໬Ꮫ㒊㒊㛛 ᭷ᶵ࣭⏕࿨໬Ꮫศ㔝ᆏཱྀ ࿴㟹㸦ᶵჾ฼⏝㸧‫ۑ‬Ꮫ఍Ⓨ⾲㭯ᒸᶞࠊ㐲⸨ᣅဢࠊ㙊⏣⍠Ἠࠊ௒ᕝᩄ᫂ࠊᆏཱྀ࿴
㟹㸸⒴ᢚไࢱࣥࣃࢡ㉁ p53 ࢆ௓ࡋࡓ⣽⬊ࢫࢺࣞࢫᛂ⟅࡟ཬࡰࡍ⣽⬊࿘ᮇࡢຠᯝ.
➨ 56 ᅇ᪥ᮏ⏕໬Ꮫ఍໭ᾏ㐨ᨭ㒊౛఍, 2019 ᖺ 7 ᭶
19 ᪥, ໭ᾏ㐨኱Ꮫ㸦໭ᾏ㐨ᮐᖠᕷ㸧㭯ᒸᶞࠊ㐲⸨ᣅဢࠊ୰ᒣ⤮⨾㔛ࠊ㙊⏣⍠Ἠࠊᆏཱྀ࿴㟹ࠊ௒ᕝᩄ᫂㸸ࢩࣥࢢࣝࢭࣝゎᯒࢆ⏝࠸ࡓ⒴ᢚ
ไࢱࣥࣃࢡ㉁ p53 ࡢ㌿෗άᛶ࡜⣽⬊࿘ᮇࡢ┦㛵ゎᯒ.
ᐃ㔞⏕≀Ꮫࡢ఍ ໭ᾏ㐨࢟ࣕࣛࣂࣥ 2019, 2019 ᖺ
11 ᭶ 6 ᪥, ໭ᾏ㐨኱Ꮫ㸦໭ᾏ㐨ᮐᖠᕷ㸧㭯ᒸᶞࠊ㐲⸨ᣅဢࠊ୰ᒣ⤮⨾㔛ࠊ㙊⏣⍠Ἠࠊᆏཱྀ࿴㟹ࠊ௒ᕝᩄ᫂㸸ࢩࣥࢢࣝࢭࣝゎᯒ࡟ࡼࡿ⒴ᢚไ
ࢱࣥࣃࢡ㉁ p53 ࡢ㌿෗άᛶ࡜⣽⬊࿘ᮇࡢ┦㛵ゎᯒ.
➨ 42 ᅇ᪥ᮏศᏊ⏕≀Ꮫ఍ᖺ఍, 2019 ᖺ 12 ᭶ 3 ᪥,⚟ᒸᅜ㝿఍㆟ሙ࣭⚟ᒸࢧࣥࣃࣞࢫ ࣍ࢸࣝ&࣮࣭࣐࣓࣍ࣝࣜࣥࢵࢭ⚟ᒸ㸦⚟ᒸ┴⚟ᒸᕷ㸧⏕≀⛉Ꮫ㒊㒊㛛 ከᵝᛶ⏕≀Ꮫศศ㔝ቑ⏣ 㝯୍◊✲ࢢ࣮ࣝࣉ㸸⌮Ꮫ◊✲㝔⏕≀⛉Ꮫ㒊㛛ቑ⏣㝯୍ࠊす⏣⩏᠇୺࡞◊✲ᡂᯝࡣ௨ୗࡢ㏻ࡾ࡛࠶ࡿࠋ
(1) ࣮ࣘࣛࢩ࢔኱㝣࡟࠾ࡅࡿ࢔ࢪ࢔࢔ࢼࢢ࣐࡜ࣚ
࣮ࣟࢵࣃ࢔ࢼࢢ࣐ࡢ㞧✀໬㏆⦕࡞࢔ࢼࢢ࣐ 2 ✀ࠊ࢔ࢪ࢔࢔ࢼࢢ࣐㸦Meles
leucurus㸧࠾ࡼࡧ࣮ࣚࣟࢵࣃ࢔ࢼࢢ࣐㸦M. meles㸧ࡣࣟࢩ࢔ࡢ࣎ࣝ࢞ᕝ-࣐࢝ᕝὶᇦࢆࢥࣥࢱࢡࢺࢰ
࣮ࣥ࡜ࡋ࡚ࠊྛࠎࡀᮾഃ࡜すഃ࡟ศᕸࡋ࡚࠸ࡿࠋ
ࡇࢀࡽ 2 ✀ࡢ㞧✀໬ࡀ⏕ࡌ࡚࠸ࡿ࠿࡝࠺࠿ࢆㄪ࡭
ࡿࡓࡵࠊࣟࢩ࢔࡜ࡢඹྠ◊✲࡜ࡋ࡚ࠊࢥࣥࢱࢡࢺ
ࢰ࣮ࣥ࿘㎶ࡢ࢔ࢼࢢ࣐࡟ࡘ࠸࡚ࠊẕ⣔㑇ఏᏊ㸦࣑ࢺࢥࣥࢻࣜ࢔ DNA㸧ࠊ∗⣔㑇ఏᏊ㸦SRY 㑇ఏᏊࠊ
CAN-SINE in ZFY㸧࠾ࡼࡧ୧ᛶ㑇ఏᏊ㸦CFTR 㑇ఏᏊࠊ࣐࢖ࢡࣟࢧࢸࣛ࢖ࢺ㸧ࡢ㑇ఏᏊᆺࢆศᯒࡋࡓࠋ
ࡑࡢ⤖ᯝࠊึࡵ࡚㞧✀ಶయࢆ᳨ฟࡍࡿࡇ࡜ࡀ࡛ࡁ
ࡓࠋࡑࡢ㞧✀໬ࡣࠊ୍ᗘࠊ୧✀ࡢ㞧✀ࡀᙧᡂࡉࢀ
ࡓᚋࠊ࡝ࡕࡽ࠿୍᪉ࡢ✀࡜ࡢᡠࡋ஺㞧ࡢ཯᚟࡟ࡼ
ࡾᵝࠎ࡞⛬ᗘ࡟ᙧᡂࡉࢀ࡚࠸ࡿࡇ࡜ࡀ᫂ࡽ࠿࡟࡞
ࡗࡓࠋࠕKinoshita et al. (2019)ࡼࡾࠖ
(2) ࢔ࢼࢢ࣐ᒓ࡟࠾ࡅࡿ⮅⮚ᆺ࢔࣑࣮ࣛࢮ㑇ఏᏊࡢࢥࣆ࣮ᩘࡢከᵝᛶ࡜㣗ᛶ့ங㢮ࡣࠊࢹࣥࣉࣥศゎ㓝⣲࡛࠶ࡿ࢔࣑࣮ࣛࢮࡢ
㑇ఏᏊᗙᩘࢆ㔜」㐍໬ࡉࡏࡿࡇ࡜࡟ࡼࡾࠊࢹࣥࣉ
ࣥ㇏ᐩ࡞㣗ᛶ࡬ࡢ㐺ᛂࢆࡣ࠿ࡗ࡚ࡁࡓࡢ࡛ࡣ࡞࠸
࠿࡜⪃࠼ࡽࢀ࡚࠸ࡿࠋࡑࡇ࡛ࠊⲡ㣗ᛶࠊ⫗㣗ᛶࠊ㞧㣗ᛶࡢ✀ࢆྵࡴ࢖ࢱࢳ⛉࡟ࡘ࠸࡚⮅⮚ᆺ࢔࣑࣮ࣛࢮ㑇ఏᏊ㸦AMY2㸧ࡢࢥࣆ࣮ᩘࢆࣜ࢔ࣝࢱ࢖࣒
PCR ἲ࡟ࡼࡾゎᯒࡋࡓ࡜ࡇࢁࠊ࢔ࢪ࢔࢔ࢼࢢ࣐࡟
࠾࠸࡚㸯ࢥࣆ࣮࠿ࡽ 4 ࢥࣆ࣮ࡢ㛫࡛㔜」ࡋ࡚࠸ࡿ
ࡇ࡜ࡀ᫂ࡽ࠿࡟࡞ࡗࡓࠋࡑࢀ࡟ᑐࡋࠊ௚ࡢ࢔ࢼࢢ
࣐ᒓࡸ௚ࡢ࢖ࢱࢳ⛉ࢸࣥᒓࡸ࢖ࢱࢳᒓ࡛ࡢࢥࣆ࣮
ᩘࡣ 1 ࢥࣆ࣮ࡢࡲࡲ࡛࠶ࡗࡓࠋ࢔ࢼࢢ࣐ᒓࡣ୍⯡ⓗ࡟㞧㣗ᛶ࡛࠶ࡿࡀࠊ࢔ࢪ࢔࢔ࢼࢢ࣐ࡣ௚✀࡟ẚ࡭࡚㣗ᛶࡢᖜࡀᗈࡃ࡞ࡾࠊ⎔ቃ࡬ࡢ㐺ᛂᗘࡀ㧗ࡃ࡞ࡗ࡚࠸ࡿྍ⬟ᛶࡀ⪃࠼ࢀࡿࠋࠕAbduriyim et al.
(2019a)ࡼࡾࠖ
(3)࢔ࢼࢢ࣐ᒓ࡟࠾ࡅࡿ୺せ⤌⧊㐺ྜ㑇ఏᏊ」ྜయ
㸦MHC㸧ࢡࣛࢫ I ࡢศᏊ㐍໬့ங㢮ࡢච␿⣔࡟࠾࠸࡚ᢠཎࡢㄆ㆑ࢆ⾜࠺ MHC
ࢱࣥࣃࢡ㉁ࡣࠊ࢘࢖ࣝࢫࢱࣥࣃࢡ㉁ࡸ⒴໬࡞࡝࡟
ࡼࡿෆᅾᛶࡢ␗ᖖࢱࣥࣃࢡ㉁ࢆㄆ㆑ࡍࡿ Class I ࡜እ᮶ᢠཎࢆㄆ㆑ࡍࡿ Class II ࡟ศ㢮ࡍࡿࡇ࡜ࡀ࡛
ࡁࡿࠋࡇࡢෆࡢ Class I ࡟ࡘ࠸࡚ࠊ࣮ࣘࣛࢩ࢔࡟⏕ᜥࡍࡿ 4 ✀ࡢ࢔ࢼࢢ࣐㸦࢔ࢪ࢔࢔ࢼࢢ࣐ࠊ࣮ࣚࣟ
ࢵࣃ࢔ࢼࢢ࣐ࠊࢽ࣍ࣥ࢔ࢼࢢ࣐ࠊ୰ᮾ࢔ࢼࢢ࣐㸧࡟ࡘ࠸࡚ศᏊ㐍໬Ꮫⓗゎᯒ࡟ࡼࡿẚ㍑ࢆ⾜ࡗࡓࠋ✀࡟ࡼࡾ␗࡞ࡿࡀࠊ1 ✀࠶ࡓࡾ 7–21 ✀ࠊ1 ಶయ࠶ࡓࡾ 2–7 ᗙ఩ࡢ Class I ࢱࣥࣃࢡ㉁ࢆࢥ࣮ࢻࡍࡿᑐ
❧㑇ఏᏊ㸦MHC I 㑇ఏᏊ㸧ࡀぢ࠸ࡔࡉࢀࡓࠋᢠཎ
ࡣࠊࢱࣥࣃࢡ㉁୰ࡢ 2 ࡘࡢ⌫≧ࢻ࣓࢖ࣥD1ࠊD2 ࡟ྵࡲࢀࡿ≉ᐃࡢ࢔࣑ࣀ㓟ṧᇶ㸦ᢠཎ⤖ྜ㒊఩㸧࡜⤖ྜࡍࡿࡓࡵࠊࡇࢀࡽࢆࢥ࣮ࢻࡍࡿ exon 2, 3 ࠾ࡼࡧࡑࡢ㛫ࡢ intron 2 ࡟ࡘ࠸࡚ࠊከᵝᛶゎᯒࢆ⾜ࡗࡓࠋࡑࡢ⤖ᯝࠊexon 2 ࡛ࡣṇࡢ⮬↛㑅ᢥࡀࠊexon 3 ࡛ࡣṇࡢ⮬↛㑅ᢥ࡜⤌᭰࠼ࡀከᵝᛶࢆࡶࡓࡽࡋ࡚࠸
ࡿࡇ࡜ࡀ♧ࡉࢀࡓࠋ2 ࡘࡢ exon 㛫࡛㑇ఏⓗ≉ᛶࡢᕪ␗ࡀぢࡽࢀࡓࡓࡵࠊMHC I 㑇ఏᏊࡣ␗࡞ࡿ┦ྠᛶࡢ㧗࠸㑇ఏᏊ㛫࡛ࡢ⤌᭰࠼࡟ࡼࡾᙧᡂࡉࢀࡓྍ
⬟ᛶࡀ࠶ࡿࠋࡲࡓࠊ࣋࢖ࢬἲ࡟ࡼࡿ⣔⤫ᶞ୰࡛✀ࢆ㉸࠼ࡓከᆺࡀぢࡽࢀࡓࡇ࡜࠿ࡽࠊࡇࡢ㑇ఏᏊᗙ
ࡢከᵝᛶࡢ⥔ᣢ࡟ࡣᖹ⾮㐍໬ࡀᐤ୚ࡋ࡚࠸ࡿࡇ࡜
ࡀ♧၀ࡉࢀࡓࠋࠕAbduriyim et al. (2019b)ࡼࡾࠖ
Ⓨ⾲ㄽᩥ
1. Kinoshita, E., Abramov, A.V., Soloviev, V.A.,
Saveljev, A.P., Nishita, Y., Kaneko, Y., and Masuda,
R. (2019) Hybridization between the European andAsian badgers (Meles, Carnivora) in theVolga-Kama region, revealed by analyses ofmaternally, paternally and biparentally inheritedgenes. Mammalian Biology 94: 140-148.
2. Abduriyim, S., Nishita, Y., Abramov, A.V.,− 35 −

Solovyev, V.A., Saveljev, A.P., Kosintsev, P.A.,
Kryukov, A.P., Raichev, G.E., Väinölä, R., Kaneko,Y., and Masuda, R. (2019a) Variation in pancreaticamylase gene copy number among Eurasianbadgers (Carnivora, Mustelidae, Meles) and its
relationship to diet. Journal of Zoology 308: 28-36.
3. Abduriyim, S., Nishita, Y., Kosintsev, P.A.,
Raichev, E., Väinölä, R., Kryukov, A.P, Abramov,
A.V., Kaneko, Y., and Masuda, R. (2019b)
Evolution of MHC class I genes in Eurasianbadgers, genus Meles (Carnivora, Mustelidae).
Heredity 122: 205-218.
4. Nishita, Y., Spassov, N., Peeva, S., Raichev, E.G.,
Kaneko, Y., and Masuda, R. (2019) Genetic
diversity of MHC class II DRB alleles in themarbled polecat, Vormela peregusna, in Bulgaria.
Ethology, Ecology and Evolution 31: 59-72.
5. Puzachenko, A.Yu., Masuda, R., and Abramov, A.V.
(2019) Sexual dimorphism of craniologicalcharacters in the Altai weasel Mustela altaica(Carnivora, Mustelidae). Russian Journal of
Theriology 18: 12-19.
Ꮫ఍Ⓨ⾲
1. す⏣⩏᠇㸪Risto Väinölä㸪Alexei V. Abramov㸪ቑ⏣㝯୍㸸࣮ࣚࣟࢵࣃ໭㒊ཬࡧᮾ㒊࡟⏕ᜥࡍࡿ࣐ࢶࢸࣥ㞟ᅋࡢ୺せ⤌⧊㐺ྜ㑇ఏᏊ」ྜయ
㸦MHC㸧ࢡࣛࢫII DRB㑇ఏᏊࡢከᵝᛶ㸬᪥ᮏ့ங㢮Ꮫ఍2019ᖺᗘ኱఍㸪2019ᖺ9᭶16ࠥ18᪥㸪୰ኸ኱Ꮫ㸦ᮾி㸧㸬ࠕ࣏ࢫࢱ࣮Ⓨ⾲ࠖ
2. ⣽㇂⚈ኸ㸪す⏣⩏᠇㸪ቑ⏣㝯୍㸸᪥ᮏᅛ᭷✀࣍ࣥࢻࢸࣥ࡟࠾ࡅࡿ୺せ⤌⧊㐺ྜ㑇ఏᏊ」ྜ
యࢡࣛࢫII DRB㑇ఏᏊࡢ㑇ఏⓗከᵝᛶ࡜㐍໬㸬᪥ᮏ့ங㢮Ꮫ఍2019ᖺᗘ኱఍㸪2019ᖺ9᭶16ࠥ
18᪥㸪୰ኸ኱Ꮫ㸦ᮾி㸧㸬ࠕ࣏ࢫࢱ࣮Ⓨ⾲ࠖ
3. 㐲⸨ඃ㸪Liang-Kong Lin㸪ᒣᓮ᫭ྖ㸪Kurtis
Jai-Chyi Pei㸪Shih-Wei Chang㸪Yen-Jean Chen㸪ⴠྜၨ஧㸪㇂ᆅ᳃⚽஧㸪ጜᓮᬛᏊ㸪㔠Ꮚᘺ⏕㸪ቑ⏣㝯୍㸸࣑ࢺࢥࣥࢻࣜ࢔DNAศᯒ࡟ᇶ࡙ࡃ
᪥ᮏࡢࣁࢡࣅࢩࣥࡢ⛣ධ࣭ศᕸᣑ኱ࡢゎ᫂㸬᪥ᮏ့ங㢮Ꮫ఍2019ᖺᗘ኱఍㸪2019ᖺ9᭶16ࠥ
18᪥㸪୰ኸ኱Ꮫ㸦ᮾி㸧㸬ࠕ࣏ࢫࢱ࣮Ⓨ⾲ࠖ
4. Aye Mee F. Bartocillo㸪Yoshinori Nishita㸪Alexei
V. Abramov㸪Ryuichi Masuda㸸Genetic diversity
and evolution of MHC class II DRB gene inJapanese and Russian raccoon dogs㸬᪥ᮏ့ங㢮
Ꮫ఍2019ᖺᗘ኱఍㸪2019ᖺ9᭶17᪥㸪୰ኸ኱Ꮫ㸦ᮾி㸧㸬ࠕཱྀ㢌Ⓨ⾲ࠖ
5. ኳụᗤ௓㸪ᓊ⏣᐀⠊㸪㓇ྥ㈗Ꮚ㸪ᡭሯ∾ே㸪ቑ⏣㝯୍㸸⣅DNAゎᯒ࡟ࡼࡗุ࡚᫂ࡋࡓⓚᒃࢱࢾ࢟ࡢ㑇ఏᵓ㐀࡜⁀ࡵ⣅ሙ฼⏝ᵝᘧ㸬᪥ᮏື≀Ꮫ఍➨90ᅇ኱㜰኱఍㸪2019ᖺ9᭶12᪥㸪኱㜰ᕷ❧኱Ꮫ㸦኱㜰ᕷ㸧㸬ࠕཱྀ㢌Ⓨ⾲ࠖ

6.

Takuma Sato, Ryuichi Masuda: Local population
structure and micro habitat of the feral Japanesemarten in Hokkaido, Japan, based on fecal DNA
analysis. 33rd European Mustelid Colloquium,
October 9, 2019, Lisbon (Portugal). ”Poster
presentation”኱Ꮫ㝔ඛඛ➃⏕࿨⛉Ꮫ◊✲㝔⏕࿨ᶵ⬟⛉Ꮫ◊✲㒊㛛⏕≀᝟ሗゎᯒ⛉Ꮫ◊✲ศ㔝ฟᮧ ㄔ㸦ᶵჾ฼⏝㸧࠙Ꮫ⾡ㄽᩥࠚ
Horie, Y., Nemoto, H., Fujita, J., Ikegawa, S., Kumaki,Y., Ohnishi, Y., Kumeta, H., Demura, M., Aizawa, T.
(2019) Studies on the Quality Control of Fermented
Brown Rice and Rice Bran with Aspergillus oryzae by
Metabolome Analysis Using 1H-NMR1H-NMR :Nippon Shokuhin Kagaku Kogaku Kaishi 66(4) :139-146
Poncet, P., Aizawa, T., Sénéchal, H. (2019) The
subtype of Cupressaceae pollinosis associated with Pru
p 7 sensitization is characterized by a sensitization to across-reactive gibberellin-regulated protein in cypress
pollen: BP14. Clinical & Experimental Allergy 49(8) :1163-1166
Yanagi, T., Takagi, T., Takahashi, H., Kikukawa, T.,Amii, H., Sonoyama, M. (2019) Comparison of two
different partially fluorinated phosphatidylcholines
with the perfluorobutyl group on thermotropic
properties of the bilayer membrane and reconstitutedbacteriorhodopsin. : Biophysical Reviews 11(3) : 395-398
Yamanashi, T., Maki, M., Kojima, K., Shibukawa, A.,
Tsukamoto, T., Chowdhury, S., Yamanaka, A., Takagi,S., Sudo, Y. (2019) Quantification of the neuralsilencing activity of anion channelrhodopsin in
Caenorhabditis elegansand their applicability forlong-term illumination : Scientific Reports 9(1) : 7863
Geng, X., Dai, G., Chao, L., Wen, D., Kikukawa, T.,
Iwasa, T. (2019) Two Consecutive Polar Amino Acids
at the End of Helix E are Important for Fast Turnoverof the Archaerhodopsin Photocycle : Photochemistry
and Photobiology 95(4) : 980-989
Iizuka, A., Kajimoto, K., Fujisawa, T., Tsukamoto, T.,
Aizawa,,T., Kamo, N., Jung, K.H., Unno, M., Demura,M., Kikukawa, T.(2019) Functional importance of theoligomer formation of the cyanobacterial H+ pumpGloeobacter rhodopsin : Scientific Reports 9(1) : 10711
Fujisawa, T., Kiyota, H., Kikukawa, T., Unno, M. (2019)
Low-Temperature Raman Spectroscopy of Halorhodopsin
from Natronomonas pharaonis:Structural Discriminationof Blue-Shifted and Red-Shifted Photoproducts :Biochemistry 58(40) : 4159-4167− 36 −

Sato, T., Kikukawa, T., Miyoshi, R., Kajimoto, K., Yonekawa,C., Fujisawa, T., Unno, M., Eki, T., Hirose, Y. (2019)
Protochromic absorption changes in the two-cysteine
photocycle of a blue/orange cyanobacteriochrome : The
Journal of Biological Chemistry 294(49) : 18909-18922
Hirabayashi, Y., Nakamura, K., Sonehara, T., Suzuki,D., Hanzawa, S., Shimizu, Y., Aizawa, T., Nakamura,K., Tamakoshi, A., Ayabe, T. (2020) Analysis of
Serotonin in Human Feces Using Solid Phase
Extraction and Column-switching LC-MS/MS : Mass
Spectrometry 8 : A0081
Yamamura, R., Nakamura, K., Kitada, N., Aizawa, T.,
Shimizu, Y., Nakamura, K., Ayabe, T., Kimura, T.,
Tamakoshi, A. (2020) : Associations of gut microbiota,
dietary intake, and serum short-chain fatty acids withfecal short-chain fatty acids. : Biosci Microbiota Food
Health. 39(1) : 11-17
࠙Ꮫ఍Ⓨ⾲ࠚ
ୖ஭ᖾྖ㸪ஂ⡿⏣༤அ㸪ஂಖ◊஧㸪Ώ㑓㍤㸪㛵༓ⲡ㸪୰㔝༤ே㸪┦ἑᬛᗣ㸪ᚨᵹΎᏕ㸸᰾☢Ẽඹ㬆ἲ࡟ࡼࡿ㣗ရࡢㄆ▱ᶵ⬟㛵㐃ࢱࣥࣃࢡ⤖ྜࢫࢡ࣮ࣜࢽࣥࢢ㸬᪥ᮏ㣗ရ໬ᏛᏛ఍➨ 25 ᅇ⥲఍࣭Ꮫ⾡኱఍㸪2019 ᖺ 6 ᭶ 6 ᪥㸪࢟ࢵࢭ࢖ᩥ໬࣮࣍ࣝ㸦ᯇᮏᕷ㸧≀⌮Ꮫ఍ᖺ఍㸪2019 ᖺ 9 ᭶ 24 ᪥㸪ࢩ࣮࢞࢖࢔ࢥ
ࣥ࣋ࣥࢩࣙࣥࢭࣥࢱ࣮㸦ᐑᓮᕷ㸧㑣㡲㐶㤶 , బ⸨ඃḟ , ሯᮏ༟ , ⳥ᕝᓠᚿ , ฟᮧ
ㄔ , ┦ἑᬛᗣ㸸⣽⬊≉␗ⓗࢤࣀ࣒⦅㞟ࢆ┠ⓗ࡜ࡋࡓ᰾㓟ࢆࢹࣜࣂ࣮ࣜࡍࡿ᪂つ୍ᮏ㙐ᢠయ scFv ࡢస〇㸬➨ 57 ᅇ᪥ᮏ⏕≀≀⌮Ꮫ఍ᖺ఍㸪2019 ᖺ 9 ᭶
24 ᪥㸪ࢩ࣮࢞࢖࢔ࢥࣥ࣋ࣥࢩࣙࣥࢭࣥࢱ࣮㸦ᐑᓮᕷ㸧
Kitahara,T., Kurane, H., Kikuchi, C., Aizawa, T.,
Kikukawa, T., Demura, M., Tsukamoto,T.㸸An Anion
Channelrhodopsin with a Naturally Super-Slow
Photocycle㸬➨ 57 ᅇ᪥ᮏ⏕≀≀⌮Ꮫ఍ᖺ఍㸪2019ᖺ 9 ᭶ 24 ᪥㸪ࢩ࣮࢞࢖࢔ࢥࣥ࣋ࣥࢩࣙࣥࢭࣥࢱ࣮
㸦ᐑᓮᕷ㸧
Iwama, K., Watanabe, Y., Tsukamoto, T., Aizawa, T.,
Demura, M., Kikukawa,T.,㸸Mastigocladopsis repens
halorhodopsin ࡢ Cl-࣏ࣥࣉάᛶ࡟࠾ࡅࡿ His166 ࡢ㔜せᛶ㸬➨ 57 ᅇ᪥ᮏ⏕≀≀⌮Ꮫ఍ᖺ఍㸪2019 ᖺ 9
᭶ 24 ᪥㸪ࢩ࣮࢞࢖࢔ࢥࣥ࣋ࣥࢩࣙࣥࢭࣥࢱ࣮㸦ᐑᓮᕷ㸧
Kikuchi, C., Aizawa, T., Kikukawa, T., Demura, M.,
Tsukamoto, T.㸸Comparative Study for Anion Transport
Activity of Anion Channelrhodopsins by Using a
Simple pH Electrode Method㸬➨ 57 ᅇ᪥ᮏ⏕≀≀⌮Ꮫ఍ᖺ఍㸪2019 ᖺ 9 ᭶ 24 ᪥㸪ࢩ࣮࢞࢖࢔ࢥࣥ࣋
ࣥࢩࣙࣥࢭࣥࢱ࣮㸦ᐑᓮᕷ㸧

Kikukawa, T., Sasaki, S., Nishiya, K., Tsukamoto, T.,
Aizawa, T., Demura, M., Tamogami,J.㸸Replacementsof “H+ donor” residues in the light-driven H+-pumprhodopsins㸬17th International Congress on Photobiology㸪ᑠᯇ㝧௓, ΎỈ⏤Ᏹ, ᒣ㔝ࡵࡄࡳ, ୰ᮧබ๎, ⥤㒊2019 ᖺ 8 ᭶ 27 ᪥㸪Hotel Crowne Plaza Barcelona Fira᫬ⰾ, ┦ἑᬛᗣ㸸ࢡ࣮ࣟࣥ⑓⮬↛Ⓨ⑕ࣔࢹࣝ
Center㸦ࣂࣝࢭࣟࢼ㸧
SAMP1/YitFc ࣐࢘ࢫࡢ⑓≧㐍⾜࡟క࠺⭠ෆ⣽⳦ྀ⳥ᕝᓠᚿ㸸ᚤ⏕≀ࣟࢻࣉࢩࣥࡢ࣍ࣔከ㔞యᙧᡂࡢ࠾ࡼࡧ⣅౽࣓ࢱ࣎ࣛ࢖ࢺࡢኚື㸬➨ 71 ᅇ᪥ᮏ⏕≀ᶵ⬟ⓗព⩏㸬ISSP ࣮࣡ࢡࢩࣙࢵࣉࠕࣞࢳࢼ࣮ࣝࢱ
ᕤᏛ఍኱఍㸪2019 ᖺ 9 ᭶ 17 ᪥㸪ᒸᒣ኱Ꮫὠᓥ࢟
ࣥࣃࢡ㉁ࡢගᶵ⬟Ⓨ⌧ࡢ≀⌮࡜໬Ꮫࠖࣉࣟࢢ࣒ࣛ㸪 ࣕࣥࣃࢫ㸦ᒸᒣᕷ㸧
2019 ᖺ 9 ᭶ 5 ᪥㸪ᮾி኱Ꮫ≀ᛶ◊✲ᡤ㸦᯽ᕷ㸧ᑠᯇ㝧௓, ΎỈ⏤Ᏹ, ୰ᮧබ๎, ⥤㒊᫬ⰾ, ┦ἑᬛຍ⸨ᮅஓࠊᮧ㒊ᆂ♸ࠊሯᮏ༟ࠊ┦ἑᬛᗣࠊฟᮧㄔࠊ
ᗣ㸸ࢡ࣮ࣟࣥ⑓⮬↛Ⓨ⑕ࣔࢹࣝࡢ⑓≧㐍⾜࡟క࠺⳥ᕝᓠᚿ㸸Indibacteralkaliphilus ⏤᮶ Na+࣏ࣥࣉᆺ⣅౽୰࣓ࢱ࣎ࣛ࢖ࢺࡢኚື㸬➨ 13 ᅇ࣓ࢱ࣮࣒࣎ࣟ
ࣟࢻࣉࢩࣥࡢ㍺㏦㐣⛬ࡢゎᯒ㸬ISSP ࣮࣡ࢡࢩࣙࢵ
ࢩ࣏ࣥࢪ࣒࢘㸪2019 ᖺ 10 ᭶ 18 ᪥㸪⟃Ἴ኱Ꮫ఍㤋ࣉࠕࣞࢳࢼ࣮ࣝࢱࣥࣃࢡ㉁ࡢගᶵ⬟Ⓨ⌧ࡢ≀⌮࡜㸦ࡘࡃࡤᕷ㸧
໬Ꮫࠖࣉࣟࢢ࣒ࣛ㸪2019 ᖺ 9 ᭶ 5 ᪥㸪ᮾி኱Ꮫ≀Gu, H., Onuma, K., Ishida, H., Kumaki, Y., Tsukamoto,ᛶ◊✲ᡤ㸦᯽ᕷ㸧T., Kikukawa, T., Demura, M., Vogel, H. J., Aizawa,
T.㸸The study of overexpression and purification of⳥ᕝᓠᚿࠊబࠎᮌᑗఃࠊす㇂ᏹ㍤ࠊሯᮏ༟ࠊ┦ἑ
recombinant small peptides through a calmodulinfusionᬛᗣࠊฟᮧㄔࠊ⏣ẕ⚄῟㸸H㸩࣏ࣥࣉᆺࣟࢻࣉࢩࣥ
protein system㸬The 7th International Life-Scienceࡢ H+ࢻࢼ࣮ṧᇶ࡟㛵ࡍࡿ◊✲㸬ISSP ࣮࣡ࢡࢩࣙ
Symposium(ILSS2019)㸪2019 ᖺ 11 ᭶ 1 ᪥㸪Hokkaidoࢵࣉࠕࣞࢳࢼ࣮ࣝࢱࣥࣃࢡ㉁ࡢගᶵ⬟Ⓨ⌧ࡢ≀⌮
University
Conference Hall㸦Sapporo㸧࡜໬Ꮫࠖࣉࣟࢢ࣒ࣛ㸪2019 ᖺ 9 ᭶ 5 ᪥㸪ᮾி኱Ꮫ≀ᛶ◊✲ᡤ㸦᯽ᕷ㸧
Kiyoshima, M., Kikukawa, T., Aizawa, T., Demura, M.,
Sudo, T., Tsukamoto, T.㸸Inversion of Proton Transport
Direction in Thermophilic Rhodopsin by Neutralizing
the Secondary Counterion Asp229㸬➨ 57 ᅇ᪥ᮏ⏕≀Haque, S., Kikukawa, T., Tamaoki, N.㸸Proteorhodopsin
photocycle driven by azobenzene derivatives㸬The 7thInternational Life-Science Symposium(ILSS2019) 㸪2019 ᖺ 11 ᭶ 1 ᪥㸪Hokkaido University ConferenceHall㸦Sapporo㸧− 37 −

Nasu, H., Sato, Y., Tsukamoto, T., Kikukawa, T.,
Demura, M., Aizawa, T.㸸Construction of a novel
recombinant protein based on single chain variablefragment (scFv) which delivers nucleic acid forcell-specific genome editing㸬The 7th International
Life-Science Symposium(ILSS2019)㸪2019 ᖺ 11 ᭶ 1
᪥㸪Hokkaido University Conference Hall㸦Sapporo㸧
Kiyoshima, M., Kikukawa, T., Aizawa, T., Demura, M.,
Sudo, Y., Tsukamoto, T.㸸Outward Proton Transport ofThermophilic Rhodopsin is Inverted by Neutralizing
the Secondary Counterion Asp229㸬The 7th International
Life-Science Symposium(ILSS2019)㸪2019 ᖺ 11 ᭶ 1
᪥㸪Hokkaido University Conference Hall㸦Sapporo㸧
Kitahara, T., Aizawa, T., Kikukawa, T., Demura, M.,
Tsukamoto, T. 㸸 Demonstration of a Naturally
Super-slow Photocycle of Geminigera cryophila Anion
Channelrhodopsin㸬The 7th International Life-Science
Symposium(ILSS2019)㸪2019 ᖺ 11 ᭶ 1 ᪥㸪Hokkaido
University Conference Hall㸦Sapporo㸧
Song, Z., Bao, K., Kitada, N., Kumaki, Y., Ohnishi, Y.,
Tsukamoto, T., Kikukawa, T., Demura, M., Nakamura,K., Ayabe, T., Yamamura, R., Nakamura, K., Tamakoshi,
A., Aizawa, T.㸸Analysis of human fecal metabolomics
under different storage conditions by NMR㸬The 7thInternational Life-Science Symposium(ILSS2019) 㸪2019 ᖺ 11 ᭶ 1 ᪥㸪Hokkaido University ConferenceHall㸦Sapporo㸧㇂ᪿ㸪኱἟ᖾᬦ㸪▼⏣༤᫛㸪⇃ᮌᗣ⿱㸪ሯᮏ༟㸪⳥ᕝᓠᚿ㸪ฟᮧㄔ㸪Vogel Hans J.㸪┦ἑᬛᗣ㸸࢝ࣝࣔࢪࣗࣜࣥࡢ࣌ࣉࢳࢻ⤖ྜ⬟ࢆᛂ⏝ࡋࡓ⤌᥮࠼࣌ࣉࢳࢻᏳᐃ໬኱㔞Ⓨ⌧ἲࡢ㛤Ⓨ࡜ NMR ゎᯒ㸬➨58 ᅇ NMR ウㄽ఍㸦2019㸧㸪2019 ᖺ 11 ᭶ 7 ᪥㸪ᕝᓮᕷࢥࣥ࣋ࣥࢩ࣮ࣙࣥ࣍ࣝ㸦ᕝᓮᕷ㸧

ᖺ 3 ᭶ 26 ᪥㸪ᅜ❧ி㒔ᅜ㝿఍㤋㸦ி㒔ᕷ㸧⥲ྜ༤≀㤋◊✲㒊 ㈨ᩱ㛤Ⓨ◊✲⣔Ụ⏣ ┿Ẏ㸦㸦ᶵჾ฼⏝㸧࠙ⴭ᭩ࠚࠚỤ⏣┿Ẏ㸦2019㸧ࠕ㑇㊧࠿ࡽฟᅵࡍࡿ࢔࣍࢘ࢻࣜࡢ
㦵ࡢື≀⪃ྂᏛ࡜⪃ྂ㫽㢮Ꮫࠖୖ⏣ᜨ௓⦅ࠗ㑇ఏᏊ࠿ࡽゎࡁ᫂࠿ࡍ㫽ࡢ୙ᛮ㆟࡞ୡ⏺࠘㸪235-253㸪
୍Ⰽฟ∧㸬࠙Ꮫ఍Ⓨ⾲ࠚ
ࠚἨὒỤ㸪Ụ⏣┿Ẏ㸪ᕝୖ࿴ே㸸㉁㔞ศᯒࢆ⏝࠸ࡓ㫽㢮㦵ࡢྠᐃ㸬᪥ᮏ㫽Ꮫ఍ 2019 ᖺᗘ኱఍㸪2019ᖺ 9 ᭶ 14 ᪥㸪ᖇி⛉Ꮫ኱Ꮫ㸦ᮾி㸧㸬Ụ⏣┿Ẏ㸪ἨὒỤ㸪⳥ᆅ኱ᶞ㸪Ꮮᅜᖹ㸸㛗Ụୗὶᇦࡢ᪂▼ჾ㸪✄స㎰⪔♫఍࡛ࢽ࣡ࢺࣜࡣ฼⏝ࡉࢀ࡚࠸ࡓࡢ࠿㸽㸫ࢥ࣮ࣛࢤࣥࢱࣥࣃࢡศᯒ࠿ࡽࡢ᳨
ウ㸬➨ 7 ᅇື≀⪃ྂᏛ఍㸪2019 ᖺ 6 ᭶ 16 ᪥㸪༓ⴥᕷᇙⶶᩥ໬㈈ㄪᰝࢭࣥࢱ࣮㸦༓ⴥᕷ㸧㸬Ụ⏣┿Ẏ㸪ἨὒỤ㸪ᕝୖ࿴ே㸪Ἀ⏣⤮㯞㸸ࠕ㬼ࢆᢪࡃዪࠖࡀࠕᢪࡃࠖ㫽ࡣఱ࠿㸽ࢥ࣮ࣛࢤࣥศᯒ࡜ᙧ
ែゎᯒ࠿ࡽࡢ᳨ウ㸬➨ 36 ᅇ᪥ᮏᩥ໬㈈⛉Ꮫ఍㸪2019 ᖺ 6 ᭶ 1 ᪥㸪ᮾி⸤⾡኱Ꮫ㸦ᮾி㸧㸬௨ୗࡢ」ᩘ㒊㛛฼⏝ࢢ࣮ࣝࣉࡢሗ࿌ࡣࠊᐇ㦂⏕≀ඹྠ฼⏝㒊㛛ࢆཧ↷ࠋ኱Ꮫ㝔⌮Ꮫ◊✲㝔⏕≀⛉Ꮫ㒊㛛 ⾜ື⚄⤒⏕≀Ꮫศ㔝ỈἼ ㄔ
⏕≀⛉Ꮫ㒊㛛 ⾜ື⚄⤒⏕≀Ꮫศ㔝໭⏣ ୍༤
⏕≀⛉Ꮫ㒊㛛 ⾜ື⚄⤒⏕≀Ꮫศ㔝࿴ከ ࿴ᏹ
⏕≀⛉Ꮫ㒊㒊㛛 ⏕ṪⓎ⏕⏕≀Ꮫศศ㔝ᒣୗ ṇව㒊㛛 ⏕ṪⓎ⏕⏕≀Ꮫศศ㔝⏕≀⛉Ꮫ㒊㯮ᒾ 㯞㔛
⏕≀⛉Ꮫ㒊㒊㛛 ⏕ṪⓎ⏕⏕≀Ꮫศศ㔝ᮌᮧ ᩔ
㒊㛛 ከᵝᛶ⏕≀Ꮫศศ㔝⏕≀⛉Ꮫ㒊ᑠட ୍ᘯ

ᏵᏊ㇦㸪ໟඞ㠀㸪໭⏣┤ஓ㸪⇃ᮌᗣ⿱㸪኱す⿱Ꮨ㸪ሯᮏ༟㸪⳥ᕝᓠᚿ㸪ฟᮧㄔ㸪୰ᮧබ๎㸪⥤㒊᫬ⰾ㸪ᒣᮧ෽኱㸪୰ᮧᖾᚿ㸪⋢⭜ᬡᏊ㸪┦ἑᬛᗣ㸸ࣄࢺ౽ヨᩱࡢಖᏑ᮲௳࡜࣓ࢱ࣮࣒࣎ࣟኚືࡢ NMR ゎᯒ㸬➨ 58 ᅇ NMR ウㄽ఍㸦2019㸪2019 ᖺ 11 ᭶ 7᪥㸪ᕝᓮᕷࢥࣥ࣋ࣥࢩ࣮ࣙࣥ࣍ࣝ㸦ᕝᓮᕷ㸧
Murabe, K., Kato, T., Tsukamoto, T., Aizawa, T.,
Demura, M., Kikukawa, T.㸸Time-resolved detection of
Na+ uptake and release reactions of Na+-pumping
rhodopsin㸬The 9th Asia and Oceania Conference on
Photobiology㸪2019 ᖺ 9 ᭶ 23 ᪥ Crowne PlazaQingdao
Ocean Spring Resort㸦Qingtao㸧ୖ஭ᖾྖࠊஂ⡿⏣༤அࠊ௒๓⏣኱ᮁࠊ಴㈡㔝ṇᘯࠊ㛵༓ⲡࠊ୰㔝༤ேࠊ┦ἑᬛᗣࠊᚨᵹΎᏕ㸸STD-NMRἲ࡟ࡼࡿ᳜≀ᢳฟ࢚࢟ࢫࡢ࢔࣑ࣟ࢖ࢻș⤖ྜࢫࢡ࣮ࣜࢽࣥࢢ㸬᪥ᮏ⸆Ꮫ఍➨ 140 ᖺ఍㸦ி㒔㸧
㸪2020

኱Ꮫ㝔᝟
᝟ሗ⛉Ꮫ◊
◊✲㝔

− 38 −⏕࿨ே㛫᝟ሗ⛉Ꮫ㒊㒊㛛ࣂ࢖࢜࢖ࣥࣇ࢛࣐ࢸ࢕ࢡࢫศ㔝㐲⸨ ಇᚨ

㈨ ᩱ࣭ࢭࣥࢱ࣮ ฼⏝ᡭ⥆ࡁࣇ࣮ࣟࢳ࣮ࣕࢺ㸦ᖹᡂ 23 ᖺᗘ௨㝆㸧࣭໭ᾏ㐨኱Ꮫ኱Ꮫ㝔⌮Ꮫ◊✲㝔㝃ᒓࢤࣀ࣒ࢲ࢖ࢼ࣑ࢡࢫ◊✲ࢭࣥࢱ࣮ᐇ㦂⏕≀ඹྠ฼⏝㒊㛛 ᪋タ฼⏝ࡢᡭᘬࡁ㸦ู⾲ 1 ඹྠ฼⏝ᶵჾࣜࢫࢺ ᖹᡂ 25 ᖺ 4 ᭶௨㝆㸧㸦ู⾲ 2 ᐇ㦂⏝ື≀౪⤥⣽๎㸧࣭໭ᾏ㐨኱Ꮫ኱Ꮫ㝔⌮Ꮫ◊✲㝔㝃ᒓࢤࣀ࣒ࢲ࢖ࢼ࣑ࢡࢫ◊✲ࢭࣥࢱ࣮つ⛬࣭໭ᾏ㐨኱Ꮫ኱Ꮫ㝔⌮Ꮫ◊✲㝔㝃ᒓࢤࣀ࣒ࢲ࢖ࢼ࣑ࢡࢫ◊✲ࢭࣥࢱ࣮㐠Ⴀጤဨ఍ෆつ࣭໭ᾏ㐨኱Ꮫ኱Ꮫ㝔⌮Ꮫ◊✲㝔㝃ᒓࢤࣀ࣒ࢲ࢖ࢼ࣑ࢡࢫ◊✲ࢭࣥࢱ࣮㛗㑅⪃ෆつ− 39 −

ࢭࣥࢱ࣮฼⏝ᡭ⥆ࡁࣇ࣮ࣟࢳ࣮ࣕࢺձ ஦๓࡟฼⏝ྍ⬟ᶵჾࡸࢫ࣮࣌ࢫࡢ✵ࡁ≧ἣࢆ☜ㄆࡋ࡚ୗࡉ࠸ࠋ
ࢭࣥࢱ࣮࢙࢘ࣈࢧ࢖ࢺ    https://www.sci.hokudai.ac.jp/gdynamics/ၥ࠸ྜࢃࡏඛ㸦ࢭࣥࢱ࣮஦ົ㸧e-mail : cepa@sci.hokudai.ac.jp (ෆ⥺ 3580)

Ўղ ฼⏝⏦ㄳ᭩࣭฼⏝⪅ྡ⡙ࢆࢭࣥࢱ࣮࢙࢘ࣈࢧ࢖ࢺࡼࡾࢲ࣮࢘ࣥࣟࢻࡍࡿࠋ
㸦඲㒊㛛ඹ㏻ࣇ࢛࣮࣐ࢵࢺ࡛ࡍࠋ㸧ὀ㸧ᐇ㦂⏕≀ඹྠ฼⏝㒊㛛㸦ᮾᲷ㸧฼⏝⪅ࡢ࠺ࡕ᪂つࡢ᪉࡜ࠊ⥅⥆฼⏝࡛࠶ࡿࡀ⏦ㄳෆᐜ࡟ኚ᭦ࡢ࠶ࡿ᪉ࡣࠊୖグࡢ௚ࠕᮾᲷ฼⏝⏦ㄳ᭩ࠖࡢᥦฟࡀᚲせ࡛ࡍࠋЎճ ྛᵝᘧ࡟ᚲせ஦㡯ࢆグධࡍࡿࠋЎմ グධ῭ࡳࡢྛᵝᘧࢆ⤒㈝ࡢᨭᡶ㈐௵⪅ࡢ e-mail ࢔ࢻࣞࢫ࠿ࡽࢭࣥࢱ࣮஦ົ
e-mail ࡬ࡢῧ௜࡟࡚ᥦฟࡍࡿࠋ
ὀ㸧ᡤᒓᶵ㛵࣭㒊ᒁ࡟࡚ྲྀᚓࡋࡓ࣓࣮ࣝ࢔ࢻࣞࢫ࡛࠶ࡿࡇ࡜ࠋЎյ ฼⏝チྍ᭩ࢆཷࡅྲྀࡿࠋЎն ฼⏝㛤ጞࠋ
ὀ 1㸧ධ㤋Ⓩ㘓ࡢࡓࡵࠊಶே ID ࡶูᵝᘧ࡟࡚ᥦฟࡋ࡚࠸ࡓࡔࡁࡲࡍࠋ
ὀ 2㸧ᐇ㦂⏕≀ඹྠ฼⏝㒊㛛㸦ᮾᲷ㸧฼⏝⪅ࡣࠊ஦๓࡟ࠕᮾᲷ᪂つ฼⏝⪅ㅮ⩦఍ࠖࡢཷㅮࡀᚲせ࡛ࡍࠋ− 40 −

໭ᾏ㐨኱Ꮫ኱Ꮫ㝔⌮Ꮫ◊✲㝔㝃ᒓࢤࣀ࣒ࢲ࢖ࢼ࣑ࢡࢫ◊✲ࢭࣥࢱ࣮
ᐇ㦂⏕≀ඹྠ฼⏝㒊㛛㸦ᮾᲷ㸧᪋タ฼⏝ࡢᡭᘬࡁ
㸯㸬฼⏝⏦ㄳ㸦㸯㸧 ᙜ㒊㛛㸦ᮾᲷ㸧㣫⫱ᐊ࣭ᐇ㦂ᐊ➼ࡢ฼⏝ࢆᕼᮃࡍࡿ᫬ࡣࠊ㟁ヰ࠿㟁Ꮚ࣓࣮࡛ࣝᚲࡎ஦๓࡟
ࡈ㐃⤡ࡃࡔࡉ࠸⅛
㸦㸰㸧 ◊✲ᐊࡈ࡜࡟฼⏝⏦ㄳ᭩ཬࡧ฼⏝⪅ྡ⡙࡬ᚲせ஦㡯ࢆグධࡋࠊᥦฟࡋ࡚࠸ࡓࡔࡁࡲࡍࠋ
฼⏝チྍ᭩㸦༢ᖺᗘ㸧ࢆ⤒㈝ࡢᨭᡶ㈐௵⪅ᐄ࡟Ⓨ⾜࠸ࡓࡋࡲࡍࠋ㸦㸱㸧 㑇ఏᏊ⤌᥮࠼ᐇ㦂ࡸື≀ᐇ㦂ࢆ⾜࠺᪉ࡣᏛෆࡢ࣮ࣝࣝ࡟ᚑࡗ࡚⏦ㄳࢆ⾜࠸ࠊࡑࡢチྍ␒ྕࡲࡓࡣᢎㄆ␒ྕࢆୖグ㸦㸰㸧฼⏝⏦ㄳ᭩࡟グ㍕ࡍࡿᚲせࡀ࠶ࡾࡲࡍࠋ㸦㸲㸧 ᪂つ฼⏝⪅ࡀᙜ㒊㛛ࡢධ㤋ࢩࢫࢸ࣒࡬Ⓩ㘓ࢆᕼᮃࡉࢀࡿሙྜࡣࠊ⌮Ꮫ◊✲㝔ࡢᐃࡵࡿ᭩ᘧ
࡛ࡢ⏦ㄳࡶ࠾㢪࠸ࡋࡲࡍࠋࡲࡓࠊᙜ㒊㛛୺ദࡢ฼⏝⪅ㅮ⩦఍ࡢཷㅮࡶ⩏ົ௜ࡅ࡚࠾ࡾࡲࡍࡢ
࡛ࠊᛀࢀࡎ࡟ཷㅮࡋ࡚ࡃࡔࡉ࠸ࠋ
㸦㸳㸧฼⏝⏦ㄳᡭ⥆ࡁࡣ㝶᫬ཷࡅ௜ࡅࡲࡍࠋ
㸦㸴㸧⥅⥆ࡋ࡚฼⏝ࡉࢀࡿሙྜࡢᖺᗘẖࡢ᭦᪂ᡭ⥆ࡁࡣ୙せ࡛ࡍࠋࡓࡔࡋࠊୖグ㸦㸰㸧࡟࠾࠸࡚
ᥦฟࡋࡓෆᐜ࡟ኚ᭦ࡸ㏣ຍࡀ⏕ࡌࡓሙྜ࡟ࡣᚲせ᭩㢮ࡢ෌ᥦฟࡋ࡚࠸ࡓࡔࡁࡲࡍࡢ࡛ࠊ⫋ဨࡢᣦ♧ࢆ௮࠸࡛ࡃࡔࡉ࠸ࠋ
㸦㸵㸧ୖグ㸦㸴㸧࡟࠾࠸࡚฼⏝⪅ྡ⡙࡟᪂ࡓ࡟㏣ຍࡉࢀࡓ⪅ࡣ㸦㸲㸧࡟ヱᙜࡋࡲࡍࡢ࡛ࠊྠᵝࡢᡭ⥆ࡁཬࡧ฼⏝⪅ㅮ⩦఍ࡢཷㅮࢆ࠾㢪࠸ࡋࡲࡍࠋ
㸦㸶㸧฼⏝ࢆ⤊஢ࡉࢀࡿሙྜ࡟ࡣᥦฟ᭩㢮ࡣ࠶ࡾࡲࡏࢇࡀࠊ᧔㏥ࡉࢀࡿ㸰㐌㛫๓ࡲ࡛࡟㐃⤡ࢆ࠾㢪࠸ࡋࡲࡍࠋ฼⏝ᩱ㔠ࡣ᭶༢఩࡛࠶ࡿⅬ࡟ࡈὀពࡃࡔࡉ࠸ࠋ
㸰㸬ࡆࡗṑ㢮㣫⫱ᐊ㸦㸯㸧ࡆࡗṑ㢮㣫⫱ᐊ࡟ධᐊࡢ㝿ࡣࠊ㜵␿ୖࠊᚲࡎⓑ⾰ࢆ╔⏝ࡋᑓ⏝ࡢୖᒚࡁ࡬ᒚࡁ᭰࠼࡚ࡃࡔ ࡉ࠸ࠋ㸦㸰㸧ࡆࡗṑ㢮㣫⫱ᐊ࡬ࡢື≀ࡢᦙධ࣭ᦙฟࡣࠊ㣫⫱㒊ᢸᙜ⫋ဨࡢᣦ♧࡟ᚑࡗ࡚ࡃࡔࡉ࠸ࠋ
㸦㸱㸧㸦ᐇ㦂⏝ື≀ࡢ౪⤥㸧  ᙜ㒊㛛࡛ࡣࠊࣛࢵࢺ࣭࣐࢘ࢫ➼ࡢᐇ㦂⏝ື≀ࡢ౪⤥ࢆ⾜ࡗ࡚࠾ࡾࡲࡍࠋ౪⤥ᕼᮃ⪅ࡣࠊู⾲㸰ࡢࠕᐇ㦂⏝ື≀౪⤥⣽๎ࠖ࡟ᚑࡗࡓᚲせᡭ⥆ࢆ῭ࡲࡏ࡚ࡃࡔࡉ࠸ࠋ
㸦㸲㸧㸦ື≀ࡢ㣫⫱㸧− 41 −  ື≀ࡢ⤥㣵࣭⤥Ỉ࣭ᗋᩜࡢ஺᥮ࡣࠊ฼⏝⪅ࡀ⾜ࡗ࡚ࡃࡔࡉ࠸ࠋ
㸦㸳㸧㸦࢚ࢧࠊᗋᩜ㸧     㣫⫱࡟ᚲせ࡞࢚ࢧཬࡧᗋᩜࡣ฼⏝⪅ࡀ⏝ពࡋ࡚ࡃࡔࡉ࠸ࠋࡓࡔࡋࠊᙜ㒊㛛࡛ࡶࡆࡗṑ㢮⏝ࡢ࢚ࢧ㸯⿄  ਻ࠊᗋᩜ㸯⿄  ਻ࢆᐇ㈝࡛࠾ศࡅ࡛ࡁࡲࡍࠋ
㸦㸴㸧㸦ᚤ⏕≀ࣔࢽࢱࣜࣥࢢ⾲ࡢᥦฟ㸧  㣫⫱ᐊ࡟࠾ࡅࡿఏᰁ⑓⶝ᘏࢆண㜵ࡍࡿࡓࡵࠊእ㒊ࡢᶵ㛵࠿ࡽᦙධࡋࡓື≀ࢆ㣫⫱ࡍࡿሙྜ
ࡣࠊᦙධࡍࡿື≀ࡀᙜ㒊㛛ࡢࠕᶆ‽సᴗᡭ㡰᭩ࠖ࡟つᐃࡍࡿ⑓ཎయ࡟ឤᰁࡋ࡚࠸࡞࠸ࡇ࡜ࢆ
ド᫂ࡍࡿ᭩㢮㸦ᚤ⏕≀ࣔࢽࢱࣜࣥࢢ⾲㸧ࢆணࡵᥦฟࡋ࡚ࡃࡔࡉ࠸ࠋࡓࡔࡋࠊᦙධ๓㸯ᖺ௨ෆ࡟ྠࡌᶵ㛵࠿ࡽྠ✀ࡢື≀ࢆᦙධࡋࡓ㝿࡟ᚤ⏕≀ࣔࢽࢱࣜࣥࢢ⾲ࢆᥦฟࡋࡓሙྜ࡟ࡣࠊᨵࡵ
࡚ᥦฟࡍࡿᚲせࡣ࠶ࡾࡲࡏࢇࠋ
㸦㸵㸧㸦ࡆࡗṑ㢮ฎ⨨ᐊࡢ฼⏝㸧  ࡆࡗṑ㢮㣫⫱ᐊࡢ฼⏝⪅ࡣࠊᙜ㒊㛛ෆ࡛㣫⫱ࡍࡿື≀࡬ࡢᐇ㦂ⓗฎ⌮ࢆ⾜࠺ࡓࡵ࡟ฎ⨨ᐊࢆ฼⏝ࡍࡿࡇ࡜ࡀ࡛ࡁࡲࡍࠋ฼⏝ࡋࡓ࠸ሙྜࡣ஦๓࡟✵ࡁ≧ἣࢆᢸᙜ⪅࡟☜ㄆࡋࠊ฼⏝ᕼᮃ᪥᫬࡜ฎ⨨ෆᐜࢆᢸᙜ⪅࡬࠾ఏ࠼ࡃࡔࡉ࠸ࠋ
㸱㸬࢞ࣛࢫᐊ࣭ᅡሙ
㸦㸯㸧ᘓ≀㸯㸰㝵࡟௜ᒓࡋࡓ࢞ࣛࢫᐊࠊཬࡧᒇእ࡟ᅡሙࡀ⏝ពࡉࢀ࡚࠸ࡲࡍࠋ฼⏝ࢆᕼᮃࡍࡿ㝿࡟ࡣ஦๓࡟ᢸᙜ⫋ဨ࡜฼⏝᪉ἲࢆᡴࡕྜࢃࡏࡓ࠺࠼࡛฼⏝⏦ㄳࢆࡋ࡚ࡃࡔࡉ࠸ࠋ
㸦㸰㸧฼⏝༊ᇦࡢ㝖ⲡࡸΎᤲࡣ฼⏝⪅ྛ⮬࡛⾜ࡗ࡚ࡃࡔࡉ࠸ࠋ㎰ල㢮ࡢ㈚ฟࡶ⾜ࡗ࡚࠸ࡲࡍࡢ࡛ࠊ
฼⏝ࡢ㝿࡟ࡣ⫋ဨ࡬⏦ࡋฟ࡚ࡃࡔࡉ࠸ࠋ
㸦㸱㸧᱂ᇵᗫᲠ≀ࡣᏛෆࡢᗫᲠ≀ฎ⌮᪉ἲ࡟ᚑࡗ࡚ฎศࡋ࡚ࡃࡔࡉ࠸ࠋ
㸲㸬Ỉᵴᐊ
㸦㸯㸧Ỉᵴᐊ࡟ࡣࠊ ᗘࢥࣥࢺ࣮࣮ࣟࣛ௜ࡢỈᵴࡀ⏝ពࡉࢀ࡚࠸ࡲࡍࠋࡲࡓࠊ㣫⫱Ỉ࡜ࡋ࡚஭Ỉ㸦㞧⏝Ỉ㸧࡜ᾏỈࢆ฼⏝࡛ࡁࡲࡍࠋ
㸦㸰㸧฼⏝⪅ࡣࠊ༙ᖺ࡟୍ᗘࠊỈᵴ࡜᤼Ỉ⁁ࡢᤲ㝖୪ࡧ࡟ℐ㐣◁ࡢὙίࢆ⾜ࡗ࡚ࡃࡔࡉ࠸ࠋࡲࡓࠊ
Ỉᵴࡢ฼⏝ࡀ⤊஢ࡋࡓሙྜࡶྠᵝ࡛ࡍࠋ㸳㸬ඹྠ฼⏝㸦㸯㸧฼⏝⪅ࡣࠊᙜ㒊㛛ࢆ฼⏝ࡋ࡚⾜࠺ᐇ㦂࣭◊✲ࡢ㐙⾜ୖࠊᚲせ࡜ㄆࡵࡽࢀࡿసᴗ࡟ࡘ࠸࡚ࠊ
ඹྠ฼⏝ᶵჾ㸦ู⾲㸯ཧ↷㸧ࢆ฼⏝ࡍࡿࡇ࡜ࡀ࡛ࡁࡲࡍࠋᕼᮃ⪅ࡣ⏦ㄳ᭩ࠕ฼⏝ᶵჾࠖḍ࡟

− 42 −

௜グࡋࠊ฼⏝᪉ἲࢆ⫋ဨ࡟☜ㄆࡋ࡚࠿ࡽࡈ฼⏝ࡃࡔࡉ࠸ࠋ
㸦㸰㸧㒊㛛ෆ࡛ࡢ㣫⫱࣭ᐇ㦂ࡢࡓࡵ୍᫬ⓗ࡟㣫ᩱㄪᩚᐊࢆ฼⏝ࡍࡿࡇ࡜ࡀ࡛ࡁࡲࡍࠋ౑⏝ᚋࡣᤲ㝖࣭ࢦ࣑ฎ⌮➼ࢆ⾜࠸ࠊඖࡢ≧ែ࡟ᡠࡋ࡚ࡃࡔࡉ࠸ࠋ
㸦㸱㸧㣫⫱࣭ᐇ㦂࡟⏝࠸ࡓ⬨᳝ື≀ࡢṚయࡣࠊᑓ⏝ࣇ࣮ࣜࢨ࣮࡟ᗫᲠࡋグ㘓⡙࡬ᩘ㔞➼ࢆグධࡋ
࡚ࡃࡔࡉ࠸ࠋ
㸦㸲㸧฼⏝⪅ࡀ㝶᫬฼⏝ሙᡤࢆΎᤲ࡛ࡁࡿࡼ࠺ࠊᤲ㝖㐨ලࡢ㈚ࡋฟࡋࢆ⾜ࡗ࡚࠾ࡾࡲࡍࠋ⫋ဨ࡟ࡈ┦ㄯ࠸ࡓࡔࡃ࠿ࠊ㸰㝵ᗯୗ࡟࠶ࡿࣟࢵ࣮࢝ࡢᤲ㝖㐨ලࢆࡈ౑⏝ࡃࡔࡉ࠸ࠋ
㸦㸳㸧Ᏻ඲࢟ࣕࣅࢿࢵࢺࠊ&2 ࢖࣮ࣥ࢟ࣗ࣋ࢱ➼ࡀタ⨨ࡋ࡚࠶ࡿඹྠ฼⏝ᐊࢆ฼⏝ࡍࡿሙྜࠊ฼⏝⏦ㄳ᭩࡬ࡢグ㍕ࡀᚲせ࡛ࡍࠋᐇ㦂࡟ᚲせ࡞ᾘ⪖ရࡣ฼⏝⪅ࡀ⏝ពࡋ㐺ษ࡟ᗫᲠࡋ࡚ࡃࡔࡉ࠸ࠋタ⨨ᶵჾ㢮ࡢ฼⏝᫬㛫ࡸሙᡤ➼࡟㛵ࡋ࡚ࡣ฼⏝⪅ྠኈࡀヰࡋྜ࠸ㄪᩚࡋ࡚ࡃࡔࡉ࠸ࠋ᪂ࡓ࡟
ᶵჾ➼ࢆ฼⏝ᐊ࡟ᣢࡕ㎸ࡴሙྜࠊ๓ࡶࡗ࡚⫋ဨࡲ࡛࠾▱ࡽࡏࡃࡔࡉ࠸ࠋ
㸴㸬✵ㄪ➼ࡢ␗ᖖ࣭ࢺࣛࣈࣝ
㸦㸯㸧ྛᐊ࡟࠶ࡿ✵ㄪไᚚ┙ࡣᡤᐃࡢタᐃ್࡟ࢭࢵࢺࡉࢀ࡚࠸ࡲࡍࡢ࡛ࠊኚ᭦ࢆᕼᮃࡍࡿሙྜࡣ ᚲࡎ⏦ࡋฟ࡚ࡃࡔࡉ࠸ࠋ
㸦㸰㸧ྛᐊࡢ㆙ሗタᐃ ᗘ㸦ୖ㝈࣭ୗ㝈㸧ࡣᙜ㒊㛛⫋ဨࡢ᪉࡛タᐃࡋࡲࡍࡀࠊ฼⏝ࡋ࡚࠸ࡿ㒊ᒇ࡟ࡘ࠸࡚≉࡟ᕼᮃࡀ࠶ࡿሙྜ࡟ࡣࡈ┦ㄯࡃࡔࡉ࠸ࠋ
㸦㸱㸧ᐊࡢ␗ᖖࢆ▱ࡽࡏࡿ㆙ሗ┙ࡀࠊ㸯㝵⋞㛵࣮࣍ࣝ࡜㸰㝵ᮾഃᗯୗ୰ኸཬࡧ㸰㝵ᮾഃᗯୗࡢ

໭➃࡟ഛࢃࡗ࡚࠸ࡲࡍࠋ㆙ሗࡀ㬆ࡗ࡚࠸ࡿ࡜ࡁࡣ⫋ဨ࡬㐃⤡㢪࠸ࡲࡍࠋ
㸦㸲㸧⫋ဨ୙ᅾࡢ᫬㛫ᖏ࡟㆙ሗࡀ㬆ࡗ࡚࠸ࡓࡾࢺࣛࣈࣝ࡟㐼㐝ࡋࡓࡾࡋࡓ㝿ࡣࠊ⌮Ꮫ㒊㸰ྕ㤋ࡢ㜵⅏ࢭࣥࢱ࣮㸦ෆ⥺ 㸧࡬ఏ࠼࡚ࡃࡔࡉ࠸ࠋ㸵㸬೵㟁㸦㸯㸧ᙜ㒊㛛࡟ࡣ೵㟁࡟ࡼࡿ⏕≀ཬࡧᐇ㦂⣔࡬ࡢᙳ㡪ࢆ᭱ᑠ㝈࡟㣗࠸Ṇࡵࡿࡓࡵࠊ✵ㄪ࡞࡝࡬ࡢᚲせ᭱ప㝈ࡢᶵჾࡢ㐠㌿ࢆಖドࡍࡿ⮬ᐙⓎ㟁⿦⨨ࡀഛࢃࡗ࡚࠸ࡲࡍࠋ
㸦㸰㸧⮬ᐙⓎ㟁⿦⨨ࡣ୍᫬ⓗ࡞㟁ຊ౪⤥ࡋ࠿࡛ࡁࡲࡏࢇࡢ࡛ࠊ஦๓࡟೵㟁ࡀ▱ࡽࡉࢀ࡚࠸ࡿሙྜ
ࡣ೵㟁๓࡟ᚲࡎྛᶵჾࡢ㟁※ࢆษࡗ࡚ࡃࡔࡉ࠸ࠋ
㸦㸱㸧೵㟁࡟ࡣ᩿Ỉࡀక࠺ሙྜࡀ࠶ࡾࡲࡍࠋ⤥Ỉ࣭⤥‫ࡈࡣ⏝౑ࡢࣞ࢖ࢺࡧཬ‮‬㐲៖ࡃࡔࡉ࠸ࠋ
㸦㸲㸧⥭ᛴ࡟೵㟁ࡀⓎ⏕ࡍࡿ࡜ᩘ⛊ᚋ࡟⮬ᐙⓎ㟁⿦⨨ࡀసືࡋࡲࡍࠋᩘศ⤒ࡗ࡚ࡶ㏻㟁ࡋ࡞࠸➼ࡢࢺࣛࣈࣝࡀ࠶ࡗࡓሙྜ࡟ࡣ⮳ᛴ⫋ဨ࡬㐃⤡㢪࠸ࡲࡍࠋ㸦⫋ဨ୙ᅾ᫬ࡣ㸴㸬㸦㸲㸧࡜ྠᵝ࡟ᑐ− 43 −

ᛂࡋ࡚ࡃࡔࡉ࠸ࠋ㸧㸶㸬⣧Ỉࠊ㉸⣧ỈࠊᾏỈ㸦㸯㸧ᙜ㒊㛛࡛ࡣࠊ⣧Ỉ㸦52㸧ࠊ㉸⣧Ỉ㸦࣑ࣜ 4㸧ࠊᾏỈࡢࡳࡢᥦ౪ࡶ⾜ࡗ࡚࠸ࡲࡍࠋᕼᮃ⪅ࡣ౯᱁ࢆ☜ㄆࡋࠊ฼⏝⏦ㄳ᭩ࢆᥦฟࡋ࡚ࡃࡔࡉ࠸ࠋ
㸦㸰㸧౑⏝ࡢ㝿࡟ࡣᚲせ㔞ศࡢᐜჾࢆᣢཧࡋࠊᡤᐃࡢ⏝⣬࡟グධࡋ࡚ࡈ฼⏝ࡃࡔࡉ࠸ࠋ
㸷㸬⤒㈝
㸦㸯㸧✵ㄪࠊࡑࡢ௚ㅖタഛࡢ⥔ᣢ࣭⟶⌮ࡢࡓࡵࡢㅖ⤒㈝ࡢ୍㒊࡜ඹ㏻ᾘ⪖ရࡢ㈝⏝࡜ࡋู࡚࡟ᐃ
ࡵࡿᩱ㔠ࢆ฼⏝⪅࡟㈇ᢸࡋ࡚࠸ࡓࡔࡁࡲࡍࠋ࡞࠾ࠊ฼⏝ᩱ㔠ࡣᖺᗘጞࡵ࠿ࡽ㸱ࣨ᭶ẖ࡟ᚩ཰ࡉࡏ࡚࠸ࡓࡔࡁࡲࡍࠋ
㸯㸮㸬ࡑࡢ௚
㸦㸯㸧ධ㤋ࡍࡿ㝿࡟Ⓩ㘓 ,& ࣮࢝ࢻࢆᚲࡎᦠᖏࡋ࡚ୗࡉ࠸ࠋ
㸦㸰㸧ᙜ㒊㛛ෆࡣᅵ㊊⚗Ṇ࡛ࡍࡢ࡛ࠊᑓ⏝ࡢୖᒚࡁࢆࡈ฼⏝ࡃࡔࡉ࠸ࠋ
㸦㸱㸧฼⏝⪅ࡀⓎὀࡋࡓᶵჾಟ⧋࣭≀ရࢆ┤᥋ᙜ㒊㛛࡬⣡ရࡍࡿ㝿ࡣࠊ஦๓࡟⣡ရᴗ⪅࡜⣡ရ᪥ࢆ⫋ဨ࡬㐃⤡ࡋࠊᦙධࡸసᴗࡢ᪥᫬ࡢㄪᩚࢆ⾜ࡗ࡚ࡃࡔࡉ࠸ࠋ㸦㸲㸧 ᙜ㒊㛛ෆ࡛ࡢ≀ရࡢᢅ࠸࡟ࡘ࠸࡚ࡣࠊ௨ୗࡢⅬ࡟ᚚὀពࡃࡔࡉ࠸ࠋ∝ ≀ရ࡟ࡣ඲࡚ᡤ᭷⪅࣭ᡤᒓㅮᗙ࡞࡝ࢆศ࠿ࡾࡸࡍ࠸ሙᡤ࡟᫂グࡋ࡚ࡃࡔࡉ࠸ࠋ
∝ ഛရ␒ྕࡀࡘ࠿࡞࠸ჾල࣭ᶵჾ࣭ᾘ⪖ရ࡟ࡘ࠸࡚ࡶᡤᒓࡀศ࠿ࡿࡼ࠺࡟ㅮᗙྡ➼ࢆࡈグධࡃࡔࡉ࠸ࠋ
∝ ኱ࡁ࡞㈨ᮦࡸ≀ရࢆฟࡋධࢀࡍࡿ㝿࡟ࡣࠊ஦๓࡟⫋ဨ࡬㐃⤡ࡋࠊ㐺ᐅ⏦ㄳ᭩ࡢ᭩ࡁ᥮࠼
ࢆ⾜ࡗ࡚ࡃࡔࡉ࠸ࠋ∝ ⏦ㄳࡢ㝿࡟฼⏝ሙᡤ࡜ࡋ࡚᫂グࡉࢀ࡚࠸࡞࠸ሙᡤ㸦౛࠼ࡤ⮬ศࡢ౑⏝ሙᡤ௨እࡢ㒊ᒇ࣭ᗯୗ࣭⋞㛵➼㸧࡟୍᫬ⓗ࡟࡛ࡶ≀ရࢆタ⨨ࡍࡿሙྜ࡟ࡣࠊ⫋ဨࡲ࡛ࡈ㐃⤡ࡃࡔࡉ࠸ࠋ
㸦㸳㸧฼⏝ࢆ⤊஢ࡍࡿ㝿࡟ࡣࠊ㒊ᒇ࣭ᶵჾ➼ࢆඖࡢ≧ែ࡟ᡠࡋࠊ⫋ဨࡢ☜ㄆࢆཷࡅ࡚ࡃࡔࡉ࠸ࠋ
㸦㸴㸧ᙜ㒊㛛㐠Ⴀ㈝ࡢ୍㒊ࡣࠊⓙᵝ࠿ࡽࡢ฼⏝ᩱ㔠࡟ࡼࡗ࡚㈥ࢃࢀ࡚࠸ࡲࡍࠋග⇕Ỉᩱࡣ㐠Ⴀ㈝⥲㢠ࡢከࡃࢆ༨ࡵ࡚࠾ࡾࠊᙜ㒊㛛ࢆ㐠Ⴀࡍࡿ࠺࠼࡛㈇ᢸ࡜࡞ࡗ࡚࠾ࡾࡲࡍࠋᙜ㒊㛛ࢆඹྠ฼⏝᪋タ࡜ࡋ࡚ࡼࡾ୍ᒙά⏝ࡍࡿࡓࡵ࡟ࡶࠊ㟁Ẽ࣭Ỉ㐨➼ࡢ↓㥏౑࠸ࢆ࡞ࡃࡋࠊ┬࢚ࢿࣝࢠ࣮໬ࢆᚰ᥃ࡅ࡚ࡃࡔࡉ࠸ࠋ

− 44 −ู⾲㸯ඹྠ฼⏝ᶵჾ
࣮࢜ࢺࢡ࣮ࣞࣈ㸦ඹྠᐇ㦂ᐊ㸧   ஝⇕⁛⳦ᶵ㸦ඹྠᐇ㦂ᐊ㸧    〇ịჾ㸦㣫ᩱㄪᩚᐊ㸧&2 ࢖࣮ࣥ࢟ࣗ࣋ࢱ㸦ඹྠᐇ㦂ᐊ㸧Ᏻ඲࢟ࣕࣅࢿࢵࢺ㸦ඹྠᐇ㦂ᐊ㸧㸫Υࣇ࣮ࣜࢨ࣮㸦୰ᗯୗ㸧




ู⾲㸰
ᐇ㦂⏝ື≀౪⤥⣽๎㸬 ᐇ㦂⏕≀ඹྠ฼⏝㒊㛛࡟࠾ࡅࡿ࣐࢘ࢫ࣭ࣛࢵࢺࡢ౪⤥࡟ࡘ࠸࡚ࡣࠊࡇࡢ⣽๎ࡢᐃࡵࡿ࡜ࡇࢁ࡟ࡼࡿࠋ㸬 ᐇ㦂⏝ື≀ࡣࠊཎ๎࡜ࡋ࡚◊✲ᐇ㦂⏝࡟౪⤥ࡍࡿࠋ㸬 ᐇ㦂⏝ື≀ࡢ㣫⫱⤒㈝ࡢ㈇ᢸࡣࠊḟࡢ࡜࠾ࡾ࡜ࡍࡿࠋ
ࣁࢶ࢝ࢿࢬ࣑  ⣔⤫ࠊᛶูࠊ㐌㱋ࡢ㸦࣐࢘ࢫ㸧ᣦᐃ᭷ࡾ  㢌ᙜࡓࡾ   ෇    ᣦᐃ↓ࡋ  㢌ᙜࡓࡾ   ෇ዷፎಶయ  㢌ᙜࡓࡾ  ෇ࢻࣈࢿࢬ࣑  ⣔⤫ࠊᛶูࠊ㐌㱋ࡢ㸦ࣛࢵࢺ㸧 ᣦᐃ᭷ࡾ  㢌ᙜࡓࡾ  ෇     ᣦᐃ↓ࡋ  㢌ᙜࡓࡾ   ෇ዷፎಶయ  㢌ᙜࡓࡾ  ෇ 㸬 ౪⤥ࡢ⏦㎸ࡳࡣࠊணࡵࡆࡗṑ㢮㣫⫱㒊ࡢᢸᙜ⫋ဨ࡜ᡴྜࡏࢆ⾜࠸ࠊᡤᐃࡢ⏝⣬࡟ᚲせ஦㡯ࢆグධࡢୖࠊ⾜࠺ࡇ࡜ࠋ㸬 㸬࡟つᐃࡍࡿ㈝⏝ࡢㄳồࡣࠊᐇ㦂⏕≀ඹྠ฼⏝㒊㛛ࡢ฼⏝ᩱࡢㄳồ࡟ྜࢃࡏ࡚
⾜࠺ࠋ౪⤥࡟㝿ࡋ࡚ᚲせ࡜࡞ࡿ㈝⏝࡟ࡘ࠸࡚ࡣࠊ⏦㎸⪅ࡀ㈇ᢸࡍࡿࠋ
− 45 −

໭ᾏ㐨኱Ꮫ኱Ꮫ㝔⌮Ꮫ◊✲㝔㝃ᒓࢤࣀ࣒ࢲ࢖ࢼ࣑ࢡࢫ◊✲ࢭࣥࢱ࣮つ⛬ᖹᡂ㸰㸮ᖺ㸯㸯᭶㸯᪥ᾏ኱㐩➨㸯㸳㸮ྕ 㸦㊃᪨㸧➨㸯᮲ ࡇࡢつ⛬ࡣ㸪ᅜ❧኱Ꮫἲே໭ᾏ㐨኱Ꮫ⤌⧊つ๎㸦ᖹᡂ㸯㸴ᖺᾏ኱㐩➨㸱㸯ྕ㸧➨㸰㸵᮲ࡢ㸵➨㸲㡯ࡢつᐃ࡟ᇶ࡙ࡁ㸪໭ᾏ㐨኱Ꮫ኱Ꮫ㝔⌮Ꮫ◊✲㝔㝃ᒓࢤࣀ࣒ࢲ࢖ࢼ࣑ࢡ
ࢫ◊✲ࢭࣥࢱ࣮㸦௨ୗࠕࢭࣥࢱ࣮ࠖ࡜࠸࠺ࠋ
㸧ࡢ⤌⧊ཬࡧ㐠Ⴀ࡟ࡘ࠸࡚ᐃࡵࡿࡶࡢ࡜ࡍࡿࠋ 㸦┠ⓗ㸧➨㸰᮲ ࢭࣥࢱ࣮ࡣ㸪໭ᾏ㐨኱Ꮫࡢ◊✲⪅࡟ᑐࡋ࡚㸪㑇ఏᏊཬࡧᰁⰍయ࡟㛵ࡍࡿ◊✲ࢆ⾜࠺ࡓࡵࡢ᪋タཬࡧタഛࢆᥦ౪ࡍࡿ࡜࡜ࡶ࡟㸪ື≀㸪᳜≀ࡑࡢ௚⏕≀ᮦᩱࡢ౪⤥ࢆ⾜࠺ࡇ࡜࡟ࡼࡾ㸪⏕≀⛉Ꮫศ㔝ࡢ◊✲ࡢ㐍ᒎ࡟ᐤ୚ࡍࡿࡇ࡜ࢆ┠ⓗ࡜ࡍࡿࠋ 㸦ඹྠ฼⏝㒊㛛㸧➨㸱᮲ ࢭࣥࢱ࣮࡟㸪ḟ࡟ᥖࡆࡿඹྠ฼⏝㒊㛛ࢆ⨨ࡃࠋ  ື≀ᰁⰍయඹྠ฼⏝㒊㛛  㑇ఏᏊᐇ㦂ඹྠ฼⏝㒊㛛  ᐇ㦂⏕≀ඹྠ฼⏝㒊㛛 㸦⫋ဨ㸧➨㸲᮲ ࢭࣥࢱ࣮࡟㸪ࢭࣥࢱ࣮㛗ࡑࡢ௚ᚲせ࡞⫋ဨࢆ⨨ࡃࠋ 㸦ࢭࣥࢱ࣮㛗㸧➨㸳᮲ ࢭࣥࢱ࣮㛗ࡣ㸪໭ᾏ㐨኱Ꮫ኱Ꮫ㝔⌮Ꮫ◊✲㝔ࡢᑓ௵ࡢᩍᤵཪࡣ෸ᩍᤵࢆࡶࡗ࡚඘࡚ࡿࠋ㸰 ࢭࣥࢱ࣮㛗ࡣ㸪໭ᾏ㐨኱Ꮫ኱Ꮫ㝔⌮Ꮫ◊✲㝔㛗㸦௨ୗࠕ◊✲㝔㛗ࠖ࡜࠸࠺ࠋ㸧ࡢ┘╩ࡢୗ࡟㸪ࢭࣥࢱ࣮ࡢᴗົࢆᤸ⌮ࡍࡿࠋ㸱 ࢭࣥࢱ࣮㛗ࡢ௵ᮇࡣ㸰ᖺ࡜ࡍࡿࠋ㸲 ࢭࣥࢱ࣮㛗ࡣ㸪෌௵ࡉࢀࡿࡇ࡜ࡀ࡛ࡁࡿࠋ㸳 ࢭࣥࢱ࣮㛗ࡢ㑅⪃ࡣ㸪◊✲㝔㛗ࡀ᥎⸀ࡍࡿೃ⿵⪅࠿ࡽ㸪⥲㛗ࡀ⾜࠺ࠋ㸴 ࢭࣥࢱ࣮㛗ೃ⿵⪅ࡢ㑅⪃࡟ࡘ࠸࡚ࡣ㸪◊✲㝔㛗ࡀู࡟ᐃࡵࡿࠋ 㸦㐠Ⴀጤဨ఍㸧➨㸴᮲ ࢭࣥࢱ࣮࡟㸪ࢭࣥࢱ࣮ࡢඹྠ฼⏝࡟㛵ࡍࡿ஦㡯ࡑࡢ௚ࡢࢭࣥࢱ࣮ࡢ㐠Ⴀ࡟㛵ࡍࡿ㔜せ஦㡯ࢆᑂ㆟ࡍࡿࡓࡵ㸪㐠Ⴀጤဨ఍ࢆ⨨ࡃࠋ㸰 㐠Ⴀጤဨ఍ࡢ⤌⧊ཬࡧ㐠Ⴀ࡟ࡘ࠸࡚ࡣ㸪◊✲㝔㛗ࡀู࡟ᐃࡵࡿࠋ 㸦㞧๎㸧➨㸵᮲ ࡇࡢつ⛬࡟ᐃࡵࡿࡶࡢࡢ࡯࠿㸪ࢭࣥࢱ࣮ࡢ⤌⧊ཬࡧ㐠Ⴀ࡟㛵ࡋᚲせ࡞஦㡯ࡣ㸪◊✲㝔ࡢᩍᤵ఍ࡢ㆟ࢆ⤒࡚㸪◊✲㝔㛗ࡀู࡟ᐃࡵࡿࠋ   㝃 ๎㸯 ࡇࡢつ⛬ࡣ㸪ᖹᡂ㸰㸮ᖺ㸯㸯᭶㸯᪥࠿ࡽ᪋⾜ࡍࡿࠋ㸰 ࡇࡢつ⛬ࡢ᪋⾜ᚋ㸪᭱ึ࡟௵࿨ࡉࢀࡿࢭࣥࢱ࣮㛗ࡢ௵ᮇࡣ㸪➨㸳᮲➨㸱㡯ࡢつᐃ࡟࠿࠿ࢃࡽࡎ㸪ᖹᡂ㸰㸰ᖺ㸱᭶㸱㸯᪥ࡲ࡛࡜ࡍࡿࠋ   㝃 ๎ ࡇࡢつ⛬ࡣ㸪ᖹᡂ㸰㸯ᖺ㸲᭶㸯᪥࠿ࡽ᪋⾜ࡍࡿࠋ   㝃 ๎ ࡇࡢつ⛬ࡣ㸪ᖹᡂ㸰㸵ᖺ㸲᭶㸯᪥࠿ࡽ᪋⾜ࡍࡿࠋ− 46 −

໭ᾏ㐨኱Ꮫ኱Ꮫ㝔⌮Ꮫ◊✲㝔㝃ᒓࢤࣀ࣒ࢲ࢖ࢼ࣑ࢡࢫ◊✲ࢭࣥࢱ࣮㐠Ⴀጤဨ఍ෆつ 㸦㊃᪨㸧
➨㸯᮲ ࡇࡢෆつࡣ㸪໭ᾏ㐨኱Ꮫ኱Ꮫ㝔⌮Ꮫ◊✲㝔㝃ᒓࢤࣀ࣒ࢲ࢖ࢼ࣑ࢡࢫ◊✲ࢭࣥࢱ࣮つ⛬㸦ᖹᡂ  ᖺᾏ኱㐩➨  ྕ㸧➨㸴᮲➨㸰㡯ࡢつᐃ࡟ᇶ࡙ࡁ㸪໭ᾏ㐨኱Ꮫ኱Ꮫ㝔⌮Ꮫ◊✲㝔㝃ᒓࢤࣀ࣒ࢲ࢖ࢼ࣑ࢡࢫ◊✲ࢭࣥࢱ࣮㐠Ⴀጤဨ఍㸦௨ୗࠕጤဨ఍ࠖ࡜࠸࠺ࠋ㸧ࡢ⤌⧊ཬࡧ㐠Ⴀ࡟ࡘ࠸࡚ᐃࡵࡿࡶࡢ࡜ࡍࡿࠋ 㸦ᑂ㆟஦㡯㸧➨㸰᮲ ጤဨ఍ࡣ㸪໭ᾏ㐨኱Ꮫ኱Ꮫ㝔⌮Ꮫ◊✲㝔㝃ᒓࢤࣀ࣒ࢲ࢖ࢼ࣑ࢡࢫ◊✲ࢭࣥࢱ࣮㸦ḟ᮲➨㸯㡯࡟࠾࠸࡚ࠕࢭࣥࢱ࣮ࠖ࡜࠸࠺ࠋ
㸧ࡢඹྠ฼⏝࡟㛵ࡍࡿ஦㡯ࡑࡢ௚ࡢࢭࣥࢱ࣮ࡢ㐠Ⴀ࡟㛵ࡍࡿ㔜せ஦㡯ࢆᑂ㆟ࡍࡿࠋ 㸦⤌⧊㸧
➨㸱᮲ ጤဨ఍ࡣ㸪ḟ࡟ᥖࡆࡿ⪅ࢆࡶࡗ࡚⤌⧊ࡍࡿࠋ ࢭࣥࢱ࣮㛗 ࢭࣥࢱ࣮ࡢᴗົࢆවົࡍࡿ໭ᾏ㐨኱Ꮫ኱Ꮫ㝔⌮Ꮫ◊✲㝔ࡢᩍᤵཬࡧ෸ᩍᤵ㸦ᅜ❧኱Ꮫἲே໭ᾏ㐨኱Ꮫ≉௵ᩍဨᑵᴗつ๎㸦ᖹᡂ㸯㸶ᖺᾏ኱㐩➨㸱㸳ྕ㸧➨㸱᮲➨㸰ྕ࡟ヱᙜࡍࡿ≉௵ᩍဨࢆྵࡴ㸧 ࡑࡢ௚⌮Ꮫ◊✲㝔㛗ࡀᚲせ࡜ㄆࡵࡓ⪅ ⱝᖸྡ㸰 ๓㡯➨㸱ྕࡢጤဨࡣ㸪⌮Ꮫ◊✲㝔㛗ࡀጤკࡍࡿࠋ 㸦௵ᮇ㸧
➨㸲᮲ ๓᮲➨㸯㡯➨㸱ྕࡢጤဨࡢ௵ᮇࡣ㸪㸯ᖺ࡜ࡍࡿࠋࡓࡔࡋ㸪⿵Ḟࡢጤဨࡢ௵ᮇࡣ㸪๓௵⪅ࡢṧ௵ᮇ㛫࡜ࡍࡿࠋ㸰 ๓㡯ࡢጤဨࡣ㸪෌௵ࡉࢀࡿࡇ࡜ࡀ࡛ࡁࡿࠋ 㸦ጤဨ㛗㸧
➨㸳᮲ ጤဨ఍࡟ጤဨ㛗ࢆ⨨ࡁ㸪⌮Ꮫ◊✲㝔ࡢ๪⌮Ꮫ◊✲㝔㛗ࡢ࠺ࡕ࠿ࡽ㸪⌮Ꮫ◊✲㝔㛗ࡀᣦྡࡍࡿ⪅ࢆࡶࡗ࡚඘࡚ࡿࠋ
㸦ጤဨ఍ࡢᣍ㞟ཬࡧ㆟㛗㸧➨㸴᮲ ጤဨ㛗ࡣ㸪ጤဨ఍ࢆᣍ㞟ࡋ㸪ࡑࡢ㆟㛗࡜࡞ࡿࠋ㸰 ጤဨ఍ࡣ㸪ጤဨ㛗ࡀᚲせ࡜ㄆࡵࡓሙྜ࡟ᣍ㞟ࡍࡿࡶࡢ࡜ࡍࡿࠋ㸱 ጤဨࡢ㸱ศࡢ㸯௨ୖࡢồࡵࡀ࠶ࡿሙྜ࡟ࡣ㸪ጤဨ㛗ࡣጤဨ఍ࢆᣍ㞟ࡋ࡞ࡅࢀࡤ࡞ࡽ࡞࠸ࠋ 㸦㆟஦㸧
➨㸵᮲ ጤဨ఍ࡣ㸪ጤဨࡢ㐣༙ᩘࡢฟᖍࡀ࡞ࡅࢀࡤ㆟஦ࢆ㛤ࡁ㸪㆟Ỵࡍࡿࡇ࡜ࡀ࡛ࡁ࡞࠸ࠋ㸰 ጤဨ఍ࡢ㆟஦ࡣ㸪ฟᖍጤဨࡢ㐣༙ᩘࢆࡶࡗ࡚Ỵࡍࡿࡶࡢ࡜ࡍࡿࠋ 㸦ጤဨ௨እࡢ⪅ࡢฟᖍ㸧➨㸶᮲ ጤဨ఍ࡀᚲせ࡜ㄆࡵࡓ࡜ࡁࡣ㸪ጤဨ఍࡟ጤဨ௨እࡢ⪅ࡢฟᖍࢆồࡵ㸪ㄝ᫂ཪࡣព
ぢࢆ⫈ࡃࡇ࡜ࡀ࡛ࡁࡿࠋ

− 47 − 㸦ᗢົ㸧➨㸷᮲ ጤဨ఍ࡢᗢົࡣ㸪⌮Ꮫ࣭⏕࿨⛉Ꮫ஦ົ㒊࡟࠾࠸࡚ฎ⌮ࡍࡿࠋ 㸦㞧๎㸧
➨  ᮲ ࡇࡢෆつ࡟ᐃࡵࡿࡶࡢࡢ࡯࠿㸪ጤဨ఍ࡢ㐠Ⴀ࡟㛵ࡋᚲせ࡞஦㡯ࡣ㸪ጤဨ఍ࡀู࡟ᐃࡵࡿࠋ   㝃 ๎ ࡇࡢෆつࡣ㸪ᖹᡂ㸰㸮ᖺ㸯㸰᭶㸲᪥࠿ࡽ᪋⾜ࡍࡿࠋ   㝃 ๎ࡇࡢෆつࡣ㸪ᖹᡂ㸰㸱ᖺ㸲᭶㸯᪥࠿ࡽ᪋⾜ࡍࡿࠋ− 48 −

໭ᾏ㐨኱Ꮫ኱Ꮫ㝔⌮Ꮫ◊✲㝔㝃ᒓࢤࣀ࣒ࢲ࢖ࢼ࣑ࢡࢫ◊✲ࢭࣥࢱ࣮㛗ೃ⿵⪅㑅⪃ෆつ


㸦㊃᪨㸧
➨㸯᮲ ࡇࡢෆつࡣ㸪໭ᾏ㐨኱Ꮫ኱Ꮫ㝔⌮Ꮫ◊✲㝔㝃ᒓࢤࣀ࣒ࢲ࢖ࢼ࣑ࢡࢫ◊✲ࢭࣥࢱ࣮つ⛬㸦ᖹᡂ㸰㸮ᖺᾏ኱㐩➨㸯㸳㸮ྕ㸧➨㸳᮲➨㸳㡯ࡢつᐃ࡟ᇶ࡙ࡁ㸪໭ᾏ㐨኱Ꮫ኱Ꮫ㝔⌮Ꮫ◊✲㝔㝃ᒓࢤࣀ࣒ࢲ࢖ࢼ࣑ࢡࢫ◊✲ࢭࣥࢱ࣮㛗ೃ⿵⪅㸦௨ୗࠕೃ⿵⪅ࠖ㸧ࡢ㑅⪃࡟㛵ࡋ㸪ᚲせ࡞஦㡯࡟ࡘ࠸࡚ᐃࡵࡿࡶࡢ࡜ࡍࡿࠋ
㸦ೃ⿵⪅ࡢ㑅⪃㸧➨㸰᮲ ೃ⿵⪅ࡢ㑅⪃ࡣ㸪ḟࡢ࠸ࡎࢀ࠿࡟ヱᙜࡍࡿሙྜ࡟⾜࠺ࠋ ࢭࣥࢱ࣮㛗ࡢ௵ᮇࡀ‶஢ࡍࡿ࡜ࡁࠋ ࢭࣥࢱ࣮㛗ࡀ㎡௵ࢆ⏦ࡋฟ࡚㸪⥲㛗ࡀㄆࡵࡓ࡜ࡁࠋ ࢭࣥࢱ࣮㛗ࡀḞࡅࡓ࡜ࡁࠋ
㸦ೃ⿵⪅ࡢ㑅⪃㸧➨㸱᮲ ೃ⿵⪅ࡣ㸪⌮Ꮫ◊✲㝔ࡢᑓ௵ࡢᩍᤵཬࡧ෸ᩍᤵࡢ࠺ࡕ࠿ࡽ㸪⌮Ꮫ◊✲㝔㛗ࡀᣦྡࡍࡿ⪅ࢆࡶࡗ࡚඘࡚ࡿࠋ
㸦ᩍᤵ఍ࡢሗ࿌㸧➨㸲᮲ ⌮Ꮫ◊✲㝔㛗ࡣ㸪๓᮲ࡢつᐃ࡟ࡼࡾᣦྡࡉࢀࡓೃ⿵⪅࡟ࡘ࠸࡚㸪໭ᾏ㐨኱Ꮫ኱Ꮫ㝔⌮Ꮫ◊✲㝔ᩍᤵ఍࡟ሗ࿌ࡍࡿࡶࡢ࡜ࡍࡿࠋ㝃 ๎ࡇࡢෆつࡣ㸪ᖹᡂ㸰㸮ᖺ㸯㸰᭶㸲᪥࠿ࡽ᪋⾜ࡍࡿࠋ㝃 ๎ࡇࡢෆつࡣ㸪ᖹᡂ㸰㸵ᖺ㸲᭶㸯᪥࠿ࡽ᪋⾜ࡍࡿࠋ− 49 −

໭ᾏ㐨኱Ꮫ኱Ꮫ㝔⌮Ꮫ◊✲㝔㝃ᒓࢤࣀ࣒ࢲ࢖ࢼ࣑ࢡࢫ◊✲ࢭࣥࢱ࣮ ᴫせ2020௧࿴ᖺ᭶Ⓨ⾜
ࠛ060-0810ࠉᮐᖠᕷ໭༊໭10᮲す8୎┠ࠝTelࠞ 011-706-3580
䛊Fax䛋 011-726-3476 䠄ᮾᲷ䠅 䞉 011-706-3588 䠄すᲷ䠅ࠝE-mailࠞ cepa@sci.hokudai.ac.jp
ࠝURLࠞ https://www.sci.hokudai.ac.jp/gdynamics/