GPS Safety Summary Reference No. :JIPS_MPS_SF-002_EN

GPS/JIPS Safety Summary
1. SUBSTANCE NAME
2-Isocyanatoethyl acrylate (CAS No. 13641-96-8)

2. GENERAL STATEMENT
2-Isocyanatoethyl acrylate manufactured by our company is a functional monomer characterized
by the presence of polymerizable acrylic groups and isocyanate groups that can react with various
active hydrogen compounds in the same molecule. Its high photopolymerization properties allow
the product to be used in a wide variety of applications, including resists (liquid, film, and coloringresists), adhesives and bonding agents, printed versions, paints, and surface treatment agents. It isharmful to the human body and is life threatening if inhaled. It causes irritation to the skin and may
cause allergic skin reaction. It also causes strong eye irritation. Therefore, it is necessary to wear
protective equipment during use to protect the eyes and skin and prevent inhalation.

3. CHEMICAL IDENTITY
Item
Chemical or genericnameTrade name
CAS No.
Other Nos.
Chemical Formula
Structual Formula

Source/References

Description
2-Isocyanatoethyl acrylate
Karenz AOI
13641-96-8
Japan: Chemical Substances Control Law (2)- 4063
Japan: Industrial Safety and Health Act 2-(6)- 1615
C6H7NO3

Section 3 of the SDS issued by Resonac Corporation

4. USES AND APPLICATIONS
Main uses

2-Isocyanatoethyl acrylate is used as a raw material for electronicmaterials (liquid resist, film resist, color filter resist, semiconductor tape,adhesive, bonding agent), printing (print plate, color calibration), medicalcare (soft contact lens, dental material), fiber/paper/wood (surface
treatment agent), automobile (top coat, repair paint, part paint), homeappliance (substrate, insulation material), and building materials (cementprimer, paint, bonding agent).

5. PHYSICAL/CHEMICAL PROPERTIES
2-Isocyanatoethyl methacrylate is a colorless to slightly yellow liquid, having a pungent odor. It isstable under normal use conditions, but it is polymerized by heat, light, etc. When storing, it isnecessary to avoid sunlight and to store it in a cool and dark place to avoid polymerization.
Appearance

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GPS Safety Summary Reference No. :JIPS_MPS_SF-002_EN

ColourOdour
Melting point/Boilingpoint
Flash point
Vapour pressure
Relative density
pHPartition coefficient noctanol/water(Log Pow)
Sources/references

Colourless, light yellow, transparent color
Pungent-115 ℃ / 195 ℃
92 ℃ (Cleveland open style)35.8 Pa (25℃)
1.13 （23℃）
Not applicable (insoluble in water)
1.6
Section 9 and 10 of the SDS issued by Resonac Corporation

6. HEALTH EFFECTS
Effect assessment
Acute toxicity (oral)
Acute toxicity (dermal)
Acute toxicity (inhalation:gas)
Acute toxicity (inhalation:vapour)
Acute toxicity (inhalation:dust,mist)
Skin corrosion/irritation
Serious eye damage/eye irritation,
Respiratory sensitisation
Skin sensitisation
Germ cell mutagenicity
Carcinogenicity
Reproductive toxicity
Specific target organ toxicity — Single exposure,Specific target organ toxicity (repeatedexposure)
Aspiration hazard
ReferenceseResults （GHS Hazard Classification）
Category 3 Toxic if swallowed.
Classification not possible
Not applicable
Classification not possible
Category 2 Fatal if inhaled
Category 1C Causes severe skin burns
Category 1 Causes serious eye damage
Category 1 May cause allergy or asthma
symptoms or breathing difficulties if inhaled
Category 1 May cause an allergic skin reaction
Not classified
Classification not possible
Not classified
Not classified
Not classified
Classification not possible
Section 2 and 11 of SDS issued by Resonac
Corporation• GHS (Globally Harmonized System of Classification and Labelling of Chemicals): A system that classifies chemicals
according to the type and degree of hazards, labels the information, and provides safety data sheets according to
globally harmonized rules.
• Not applicable: Since the priority of physical state, chemical structure, chemical property, and hazard items used inthe GHS classification procedures does not fall under the category, it is not subject to the classification for thecategory.
• Not classified: Sufficient information has been obtained to implement the GHS classification, and as a result of theclassification, it does not fall under any of the hazard categories specified in the GHS.
• Classification not possible : There is not enough information for GHS classification, and classification is not possible.

7. ENVIRONMENTAL EFFECTS
Effect assessment
Hazardous to the aquatic environment, shortterm (acute)Hazardous to the aquatic environment, longterm (chronic)
Hazardous to the ozone layer

Results （GHS Hazard Classification）
Category 2 Toxic to aquatic life
Category 2 Toxic to aquatic life with long
lasting effects
Classification not possible
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Sources/references

Sections 2 and 12 of the SDS issued byResonac Corporation

Environmental fate/dynamics
log Koc=2
Mobility in soil
Persistence/degradabili Biodegradation test (28 days), Not readily biodegradablety(biodegradation rate: 45%)
Biodegradation test (28 days), Inherently biodegradable (biodegradation
rate: 86.2%)
Bioaccumulationlog Pow=1.6
potential
BCF=0.46 – 8.12 (zebrafish, 28 days)
Accumulation is suggested to be low.
Conclusion about
The criteria for persistent bioaccumulative and toxic (PBT; remaining
PBT/vPvB
persistently in the environment and possessing high bioaccumulation
potential and toxicity) and very persistent and very bioaccumulative(vPvB; remaining very persistently in the environment and possessing
very high bioaccumulation potential) chemicals are believed toinapplicable.
Sources/references
Sections 12 of the SDS issued by Resonac Corporation

8. EXPOSURE
Details
Occupational
exposuresConsumer exposures
Environmental
exposures
PrecautionsExposure potentials through main uses
Exposure to this product occurs in manufacturing facilities and various
industrial facilities that use the substance, but the exposure in operators
is relatively low because all of them are in closed processes undercontrolled conditions; therefore, there is almost no possibility of
atmospheric release of the product. However, inhalation and contact
with the skin/eyes may occur during sampling, filling, and transferoperations.
This product is not used directly by general consumers.
Since our company products are typically manufactured and used inclosed processes, the potential for release into the environment islimited.
If there is a possibility of exposure in other uses, take appropriate
measures with reference to recommended risk management measures.

9. RISK MANAGEMENT RECOMMENDATIONS
Recommended risk management measures can minimize risks to workers, consumers, and theenvironment from Section 8 exposure scenarios.
Details
WorkerRisk management recommendations
Technical measures, local exhaust, and general ventilation
Provide both local exhaust ventilation and general room ventilationequipment at the site of manufacture, storage, or handling of ourcompany products, and provide emergency showers and emergency
eyewash facility near the handling site.
Permissible concentration
It is not established.

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Consumer
Environment

Special notes(emergency measuresin case of leakage, etc.)

Precautions

Protective equipment
During operation, wear a gas mask for organic gas, gloves, apron, andboots (use a chloroprene rubber protective equipment because it
penetrates nitrile rubber and vinyl chloride protective equipment) toavoid contact with the skin; also use goggles to prevent air fromentering so that eye irritation can be avoided.
Precautions
The operation manager should educate operators about the selection of
appropriate protective equipment, proper usage method, and control
method of the work site.
This product is not used directly by general consumers.
Take care not to discharge the spilled product into rivers, etc., and affectthe environment. Since the product has a strong odor or irritancy, takeappropriate measures, such as notifying people in the vicinity of theleakage.
If the product leaks, allow it to be absorbed by an absorbent, such asvermiculite, sawdust, and sand, and treat it with dilute ammonia water(e.g., 50% ethylene glycol water mixed with concentrated ammonia
water [1/10 amount]). Immediately remove ignition sources from thevicinity and prepare suitable extinguishing media (foam, carbon dioxide,powder).
For normal handling, emergency response, disposal, and transportation
control measures, refer to sections 4, 5, 6, 7, 8, 13, and 14 of the SDS
issued by Resonac Corporation.

10. STATE AGENCY REVIEW
Hazard assessment
International ChemicalSafety Cards
OECD HPVNITE-CHRIP（NITE Chemical
Risk Information Platform）

Situations of review
nonenonehttps://www.nite.go.jp/en/chem/chrip/chrip_search/srhInput

11. REGULATORY INFORMATION／GHS CLASSIFICATION AND LABELLING INFORMATION
Regulatory information only in Japan
Applicable laws
Regulatory situations
Industrial Safety andHealth Act

Not applicable

Poisonous and Deleterious
Substances Control Act

Not applicable

Fire Service Act

Category IV flammable liquids, Class Ⅲ petroleum, waterimmiscible liquids (Article 2, Paragraph 7 of the Act, Hazardous
materials, Annexed Table 1)
Poisonous substances：Poison（Article 2 and 3 of Regulations for
the Carriage and Storage of Dangerous Goods in Ship, Cabinet
Order Concerning the Control of Hazardous Materials appended
Table 1）

Ship Safety Act

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Civil Aeronautics Act
Port Regulations Act

Act on the Assessment ofReleases of Specified
Chemical Substances in theEnvironment and thePromotion of Management
Improvement and Transfer
Register / PRTR)

Properties prohibited from transportation (Article 194 of Civil
Aeronautics Act Enforcement Regulations)Hazardous materials（Poison） (Article 21-2 of the Act, Article 12of Enforcement Ordinance, Notification of the Enforcement
Regulations of the Port Regulations Act specifying the types ofhazardous materials)
Not applicable

UN classification
UN No.

6.1(8)
UN2927 TOXIC LIQUID, CORROSIVE, ORGANIC, N.O.SHazards
Physical hazards
Health hazards

Classification results (hazard information)
Flammable liquids, Category 4
Acute toxicity (oral), Category 3
Acute toxicity (inhalation:mist) Category 2
Skin corrosion/irritation Category 1C
Serious eye damage/eye irritation, Category 1
Respiratory sensitization, Category 1
Skin sensitisation, Category 1Hazardous to the aquatic environment, short-term (acute) ,Category 2
Hazardous to the aquatic environment, long-term (chronic) ,Category 2

Environmental hazards

Labelling Information
Hazard pictograms (GHS)

Signal word (GHS)
Hazard statements (GHS)

DangerCombustible liquid (H227)
Toxic if swallowed. (H301)
Causes severe skin burns and eye damage. (H314)
May cause an allergic skin reaction. (H317)
Fatal if inhaled. (H330)
May cause allergy or asthma symptoms or breathing difficulties
if inhaled. (H334)
Toxic to aquatic life with long lasting effects. (H411)

12. CONTACT INFORMATION
CompanyAddress
Departments
Tel. / Fax

Resonac Corporation
13-9, Shiba Daimon 1-chome, Minato-Ku, Tokyo, 105-8518 Japan
Functional Chemicals Business Unit Specialty Chemicals Department+81-3-6402-5080 / +81-3-5403-5730

13. DATE OF ISSUE / REVISION, ADDITIONAL INFORMATION
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GPS Safety Summary Reference No. :JIPS_MPS_SF-002_EN

Date of issue: December 27, 2022
Revisions:
Date of revision
Revised section
December 27, 2022 5, 6, 7, 11, 13
January 1, 2023
3, 6, 7, 10, 11, 12, 13

Revised item
Update to the latest information
Update to the latest information

VersionRev.2
Rev.3

The contents are based on the safety data sheet (SDS) created on January 1, 2023.
Special instructions: none

14. DISCLAIMER
The safety summary is part of the effort for the voluntary management of chemical substance inthe chemical industry (GPS/JIPS: Japan Initiative of Product Stewardship). The purpose of thesafety summary is to provide information on the safe handling of the product as an overview andnot to provide professional information, such as the risk evaluation process and its impact onhuman health and the environment. This document is not meant to serve as an alternative to risk
evaluation, such as a Safety Data Sheet (SDS) or a Chemical Safety Report (CSR). This safetysummary is being written as accurately as possible based on data such as laws, materials, andinformation available at the time of publication, but it does not include all data. It does notguarantee anything.

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