SAFETY DATA SHEET

Sikaflex®-321 HCVersion
5.0

Revision Date:
2023/03/27

SDS Number:
000000610631

Date of last issue: 2020/06/16
Date of first issue: 2016/01/27

1. PRODUCT AND COMPANY IDENTIFICATION
Chemical product name:Sikaflex®-321 HC

Supplier's company name, address and phone number
Company name of supplier: Sika Japan Ltd.
Akasaka-K-Tower 7F
1-2-7 Moto-Akasaka
Minato-ku Tokyo
107-0051 Japan
Telephone:+81 3 6434 7291

E-mail address:

EHS@jp.sika.com

Telefax:-Emergency telephone number :+81 463 24 4976

2. HAZARDS IDENTIFICATIONGHS classification of chemical product
Serious eye damage/eye irri- : Category 1tation
Carcinogenicity:

Category 2

Reproductive toxicity:

Category 1BSpecific target organ toxicity single exposure:

Category 2 (respiratory system, Central nervous system, Kidney, Liver)

Specific target organ toxicity repeated exposure:

Category 2 (Nervous system, respiratory system)

Short-term (acute) aquatic
hazard:Category 3

Long-term (chronic) aquatic
hazard:Category 3

Skin corrosion/irritation:

Category 2

GHS label elements

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SAFETY DATA SHEETSikaflex®-321 HCVersion5.0

Revision Date:
2023/03/27

SDS Number:
000000610631

Date of last issue: 2020/06/16
Date of first issue: 2016/01/27

Hazard pictograms:

Signal word:

DangerHazard statements:

H315 Causes skin irritation.
H318 Causes serious eye damage.
H351 Suspected of causing cancer.
H360 May damage fertility or the unborn child.
H371 May cause damage to organs (respiratory system, Central nervous system, Kidney, Liver).
H373 May cause damage to organs (Nervous system, respiratory system) through prolonged or repeated exposure.
H412 Harmful to aquatic life with long lasting effects.

Precautionary statements:Prevention:
P201 Obtain special instructions before use.
P202 Do not handle until all safety precautions have been readand understood.
P260 Do not breathe mist or vapours.
P264 Wash skin thoroughly after handling.
P270 Do not eat, drink or smoke when using this product.
P271 Use only outdoors or in a well-ventilated area.
P273 Avoid release to the environment.
P280 Wear protective gloves/ protective clothing/ eye protection/ face protection.
Response:
P304 + P340 + P312 IF INHALED: Remove person to fresh air
and keep comfortable for breathing. Call a POISON CENTER/
doctor if you feel unwell.
P305 + P351 + P338 + P310 IF IN EYES: Rinse cautiously withwater for several minutes. Remove contact lenses, if present
and easy to do. Continue rinsing. Immediately call a POISONCENTER/ doctor.
P308 + P311 IF exposed or concerned: Call a POISONCENTER/ doctor.
Storage:
P403 + P233 Store in a well-ventilated place. Keep container
tightly closed.
P405 Store locked up.
Disposal:
P501 Dispose of contents/ container to an approved waste
disposal plant.

Other hazards which do not result in classification
None known.
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SAFETY DATA SHEETSikaflex®-321 HCVersion
5.0

Revision Date:
2023/03/27

SDS Number:
000000610631

Date of last issue: 2020/06/16
Date of first issue: 2016/01/27

3. COMPOSITION/INFORMATION ON INGREDIENTS
Substance / Mixture:

MixtureComponents
Chemical name

CAS-No.

Concentration (% w/w)

ENCS/ISHL
number1-558, 5-5225

Titanium dioxide (> 10 μm)

13463-67-7>= 2.5 - < 10Hydrocarbons, C11-C14, nalkanes, isoalkanes, cyclics, <2%aromatics
calcium oxide

64742-47-8>= 2.5 - < 101305-78-8>= 1 - < 31-189

aluminium sulphate

10043-01-3>= 1 - < 31-25

xylene1330-20-7

1.73-3, 3-60

ethylbenzene

100-41-4>= 0.3 - < 13-28, 3-60

4,4'-methylenediphenyl diisocyanate

101-68-8>= 0.1 - < 14-118

4. FIRST AID MEASURES
General advice:

Move out of dangerous area.
Consult a physician.
Show this safety data sheet to the doctor in attendance.

If inhaled:

Move to fresh air.
Consult a physician after significant exposure.

In case of skin contact:

Take off contaminated clothing and shoes immediately.
Wash off with soap and plenty of water.
If symptoms persist, call a physician.

In case of eye contact:

Small amounts splashed into eyes can cause irreversible tissue damage and blindness.
In the case of contact with eyes, rinse immediately with plentyof water and seek medical advice.
Continue rinsing eyes during transport to hospital.
Remove contact lenses.
Keep eye wide open while rinsing.

If swallowed:

Clean mouth with water and drink afterwards plenty of water.
Do not give milk or alcoholic beverages.
Never give anything by mouth to an unconscious person.

Most important symptoms
and effects, both acute anddelayed:

Excessive lachrymation
See Section 11 for more detailed information on health effects
and symptoms.
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SAFETY DATA SHEET

Sikaflex®-321 HC
Version
5.0

Revision Date:
2023/03/27

SDS Number:
000000610631

Date of last issue: 2020/06/16
Date of first issue: 2016/01/27

irritant effects
carcinogenic effects
Causes serious eye damage.
May cause respiratory irritation.
May cause cancer.
May damage fertility or the unborn child.
May cause damage to organs.
Causes damage to organs through prolonged or repeatedexposure.
Notes to physician:

Treat symptomatically.

Suitable extinguishing media:

Carbon dioxide (CO2)

Unsuitable extinguishing
media

:

Water

5. FIREFIGHTING MEASURES

Hazardous combustion prod- :ucts

No hazardous combustion products are known

Specific extinguishing methods

Standard procedure for chemical fires.

:

Special protective equipment :for firefighters

In the event of fire, wear self-contained breathing apparatus.

6. ACCIDENTAL RELEASE MEASURES
Personal precautions, protec- :tive equipment and emergency procedures

Use personal protective equipment.
Deny access to unprotected persons.

Environmental precautions:

Do not flush into surface water or sanitary sewer system.
If the product contaminates rivers and lakes or drains inform
respective authorities.

Methods and materials forcontainment and cleaning up:

Soak up with inert absorbent material (e.g. sand, silica gel,acid binder, universal binder, sawdust).
Keep in suitable, closed containers for disposal.

Handling
Advice on protection against
fire and explosion:

Normal measures for preventive fire protection.

Advice on safe handling:

Avoid exceeding the given occupational exposure limits (see7. HANDLING AND STORAGE

4 / 13

SAFETY DATA SHEETSikaflex®-321 HCVersion5.0

Revision Date:
2023/03/27

SDS Number:
000000610631

Date of last issue: 2020/06/16
Date of first issue: 2016/01/27

section 8).
Do not get in eyes, on skin, or on clothing.
For personal protection see section 8.
Smoking, eating and drinking should be prohibited in the application area.
Follow standard hygiene measures when handling chemicalproducts
Avoidance of contact:

No data availableHygiene measures:

Handle in accordance with good industrial hygiene and safety
practice.
When using do not eat or drink.
When using do not smoke.
Wash hands before breaks and at the end of workday.

Storage
Conditions for safe storage:

Prevent unauthorized access.
Store in original container.
Keep in a well-ventilated place.
Observe label precautions.
Store in accordance with local regulations.

8. EXPOSURE CONTROLS/PERSONAL PROTECTION
Threshold limit value and permissible exposure limits for each component in the work environment
Components

CAS-No.

Hydrocarbons, C11-C14, nalkanes, isoalkanes, cyclics,<2% aromatics

64742-47-8

calcium oxide
xyleneethylbenzene

Value type(Form ofexposure)
OEL-M (Mist)

Control parameters / Permissible
concentration
3 mg/m3Basis
JP OEL
JSOH

Further information: Substance whose OEL is set based on noncarcinogenic health effects. See III, Group 1: carcinogenic to humans
TWA
200 mg/m3
ACGIH(total hydrocarbonvapor)
1305-78-8
TWA
2 mg/m3
ACGIH1330-20-7
OEL-M
50 ppmJP OEL
217 mg/m3JSOH
Further information: Group 2: Substances presumed to cause
reproductive toxicity in humans
ACL50 ppm
JP OEL ISHL
TWA20 ppm
ACGIH
100-41-4
ACL20 ppm
JP OEL ISHL
OEL-M
20 ppmJP OEL87 mg/m3
JSOH
Further information: Group 2: Substances presumed to cause
5 / 13

SAFETY DATA SHEET

Sikaflex®-321 HCVersion
5.0

Revision Date:
2023/03/27

SDS Number:
000000610631

Date of last issue: 2020/06/16
Date of first issue: 2016/01/27

reproductive toxicity in humans, Skin absorption, Group 2B: possibly carcinogenic to humans
TWA20 ppm
ACGIH
101-68-8
OEL-M
0.05 mg/m3
JP OEL
JSOH
Further information: Airway sensitizing agent; Group 1 substances
which induce allergic reactions in humans
TWA
0.005 ppm
ACGIH

4,4'-methylenediphenyl diisocyanate

Biological occupational exposure limits
Components
xyleneethylbenzene

CAS-No.

Target substance
1330-20-7 total (o-, m-,p)methylhippuric acid
Methylhippuric acids

Biologicalspecimen
Urine

100-41-4

Urine

Mandelicacid
Mandelic
acid +
Phenylglyox
ylic acid
Ethylbenzene
Sum ofmandelicacid andphenyl glyoxylic acid

Urine

Urine

Urine
Urine

Samplingtime
End ofshift at
end ofworkweek
End ofshift (Assoon aspossible
after exposureceases)
End ofshift
End ofshift at
end ofworkweek
End ofshift
End ofshift (Assoon as
possibleafter exposureceases)

Permissible
Basis
concentration
800 mg/l
JSOH

1.5 g/g creat- ACGIH
inine
BEI

150 mg/g
Creatinine
200 mg/g
Creatinine

JSOH

15 µg/lJSOH

0.15 g/g creatinine

ACGIH
BEI

JSOH

Personal protective equipment
Respiratory protection: Use respiratory protection unless adequate local exhaust
ventilation is provided or exposure assessment demonstrates
that exposures are within recommended exposure guidelines.
The filter class for the respirator must be suitable for the maximum expected contaminant concentration(gas/vapour/aerosol/particulates) that may arise when handling the product. If this concentration is exceeded, selfcontained breathing apparatus must be used.
Hand protection:

Chemical-resistant, impervious gloves complying with anapproved standard should be worn at all times when handlingchemical products if a risk assessment indicates this is nec6 / 13

SAFETY DATA SHEET

Sikaflex®-321 HCVersion
5.0

Revision Date:
2023/03/27

SDS Number:
000000610631

Date of last issue: 2020/06/16
Date of first issue: 2016/01/27

essary.
Eye protection:

Safety eyewear complying with an approved standard should
be used when a risk assessment indicates this is necessary.

Skin and body protection:

Choose body protection in relation to its type, to the concentration and amount of dangerous substances, and to the specific work-place.

9. PHYSICAL AND CHEMICAL PROPERTIES
Physical state:pasteColour:

grey, whiteOdour:characteristicOdour Threshold:

No data available

Melting point/range / Freezing :point

No data available

Boiling point/boiling range:

No data available

Flammability (solid, gas):

No data available

Lower explosion limit and upper explosion limit / flammability limit
Upper explosion limit /: No data available
Upper flammability limit
Lower explosion limit /Lower flammability limit:

No data available

Flash point:

62 °C(Method: closed cup)

Decomposition temperature:

No data available

pH:

No data available

Evaporation rate:

No data available

Auto-ignition temperature:

No data available

Viscosity
Viscosity, dynamic:

No data available

Viscosity, kinematic:

Not applicable:

No data available

Solubility(ies)
Water solubility

7 / 13

SAFETY DATA SHEET

Sikaflex®-321 HCVersion
5.0

Revision Date:
2023/03/27

SDS Number:
000000610631

Solubility in other solvents:

No data available

Partition coefficient: noctanol/water:

No data available

Vapour pressure:

0.01 hPa

Date of last issue: 2020/06/16
Date of first issue: 2016/01/27

Density and / or relative density
Density:

1.22 g/cm3 (20 °C)

Relative vapour density:No data available

Explosive properties:

No data available

Oxidizing properties:

No data available

Reactivity:

No dangerous reaction known under conditions of normal use.

Chemical stability:

The product is chemically stable.

Possibility of hazardous reactions:

No hazards to be specially mentioned.

Conditions to avoid:

No data available

Incompatible materials:

No data available

10. STABILITY AND REACTIVITY

11. TOXICOLOGICAL INFORMATION
Acute toxicity
Not classified based on available information.
Components:
xylene:Acute oral toxicity:

LD50 Oral (Rat): 3,523 mg/kgethylbenzene:
Acute oral toxicity:

LD50 Oral (Rat): 3,500 mg/kg

Acute dermal toxicity:

LD50 Dermal (Rabbit): 5,510 mg/kg

4,4'-methylenediphenyl diisocyanate:
Acute oral toxicity: LD50 Oral (Rat): > 5,000 mg/kg
Method: OECD Test Guideline 401
Acute inhalation toxicity:

LC50: 1.5 mg/l
8 / 13

SAFETY DATA SHEET

Sikaflex®-321 HC
Version
5.0

Revision Date:
2023/03/27

SDS Number:
000000610631

Date of last issue: 2020/06/16
Date of first issue: 2016/01/27

Exposure time: 4 h
Test atmosphere: dust/mist
Method: Expert judgementSkin corrosion/irritation
Causes skin irritation.
Serious eye damage/eye irritation
Causes serious eye damage.
Respiratory or skin sensitisation
Skin sensitisation
Not classified based on available information.
Respiratory sensitisation
Not classified based on available information.
Germ cell mutagenicity
Not classified based on available information.
Carcinogenicity
Suspected of causing cancer.
Reproductive toxicity
May damage fertility or the unborn child.
STOT - single exposure
May cause damage to organs (respiratory system, Central nervous system, Kidney, Liver).
STOT - repeated exposure
May cause damage to organs (Nervous system, respiratory system) through prolonged or repeatedexposure.
Aspiration toxicity
Not classified based on available information.
12. ECOLOGICAL INFORMATION
Ecotoxicity
Components:
xylene:Toxicity to fish (Chronic toxicity):

NOEC (Oncorhynchus mykiss (rainbow trout)): > 1.3 mg/l
Exposure time: 56 d

Toxicity to daphnia and other :aquatic invertebrates (Chronic toxicity)
ethylbenzene:
Toxicity to fish:

NOEC (Daphnia (water flea)): 1.17 mg/l
Exposure time: 7 d

M-Factor (Acute aquatic tox-1:

LC50 (Fish): <= 1 mg/l
Exposure time: 96 h

9 / 13

SAFETY DATA SHEET

Sikaflex®-321 HCVersion
5.0

Revision Date:
2023/03/27

SDS Number:
000000610631

Date of last issue: 2020/06/16
Date of first issue: 2016/01/27icity)
Persistence and degradability
No data available
Bioaccumulative potential
No data available
Mobility in soil
No data available
Hazardous to the ozone layer
Not applicable
Other adverse effects
Product:
Additional ecological information:

There is no data available for this product.

13. DISPOSAL CONSIDERATIONS
Disposal methods
Waste from residues:

Send to a licensed waste management company.
Do not contaminate ponds, waterways or ditches with chemical or used container.

Contaminated packaging:

Empty remaining contents.
Dispose of as unused product.
Do not re-use empty containers.
Do not burn, or use a cutting torch on, the empty drum.

14. TRANSPORT INFORMATIONInternational Regulations
UNRTDGUN number
Proper shipping nameClass
Subsidiary risk
Packing group
Labels::::::Not applicableNot applicableNot applicableNot applicableNot applicableNot applicable

IATA-DGR
UN/ID No.
Proper shipping nameClassSubsidiary risk
Packing group
Labels::::::Not applicableNot applicableNot applicableNot applicableNot applicableNot applicable
10 / 13SAFETY DATA SHEET

Sikaflex®-321 HC
Version
5.0

Revision Date:
2023/03/27

Packing instruction (cargoaircraft)
Packing instruction (passenger aircraft)
IMDG-CodeUN number
Proper shipping nameClass
Subsidiary risk
Packing group
LabelsEmS Code
Marine pollutant

SDS Number:
000000610631:

Not applicable:Not applicable

::::
:
::
:

Not applicableNot applicableNot applicableNot applicableNot applicableNot applicableNot applicableNot applicable

Date of last issue: 2020/06/16
Date of first issue: 2016/01/27

Transport in bulk according to Annex II of MARPOL 73/78 and the IBC CodeNot applicable for product as supplied.
National Regulations
Refer to section 15 for specific national regulation.
Special precautions for user
Not applicable
15. REGULATORY INFORMATION
Related Regulations
Fire Service Law
Designated Flammable Substances
Industrial Safety and Health Law
Harmful Substances Prohibited from Manufacture
Not applicable
Harmful Substances Required Permission for Manufacture
Not applicable
Substances Prevented From Impairment of Health
Not applicable
Circular concerning Information on Chemicals having Mutagenicity - Annex 2: Information on
Existing Chemicals having Mutagenicity
Not applicable
Circular concerning Information on Chemicals having Mutagenicity - Annex 1: Information on
Notified Substances having Mutagenicity
Not applicable
Substances Subject to be Notified Names
Article 57-2 (Enforcement Order Table 9)
Chemical nameTitanium(IV) oxide
Calcium oxide

Concentration (%)>=1 - <10>=1 - <10
11 / 13

Remarks-SAFETY DATA SHEET

Sikaflex®-321 HCVersion5.0

Revision Date:
2023/03/27

SDS Number:000000610631

XyleneEthylbenzene
Methylenebis(4,1-phenylene)
diisocyanate

Date of last issue: 2020/06/16
Date of first issue: 2016/01/27>=1 - <10>=0.1 - <1>=0.1 - <1-Substances Subject to be Indicated Names
Article 57 (Enforcement Order Article 18)
Chemical nameTitanium(IV) oxide
Calcium oxide
xyleneethylbenzene

Remarks-Ordinance on Prevention of Hazards Due to Specified Chemical Substances
Not applicable
Ordinance on Prevention of Lead Poisoning
Not applicable
Ordinance on Prevention of Tetraalkyl Lead Poisoning
Not applicable
Ordinance on Prevention of Organic Solvent Poisoning
Not applicable
Poisonous and Deleterious Substances Control Law
Not applicable
Act on Confirmation, etc. of Release Amounts of Specific Chemical Substances in the Environment and Promotion of Improvements to the Management Thereof
Until March 31st, 2023
Class I Designated Chemical Substances
Chemical nameCabinet Order Number
xylene80

Concentration (%)
1.7

From April 1st, 2023
Class I Designated Chemical Substances
Chemical namexyleneAdministration number
80

International Chemical Weapons Convention (CWC)
Schedules of Toxic Chemicals and Precursors
High Pressure Gas Safety Act
Not applicable16. OTHER INFORMATION
Date format:

yyyy/mm/dd
12 / 13:

Not applicable

Concentration (%)
1.7

SAFETY DATA SHEET

Sikaflex®-321 HCVersion
5.0

Revision Date:
2023/03/27

SDS Number:
000000610631

Date of last issue: 2020/06/16
Date of first issue: 2016/01/27

Full text of other abbreviations
ACGIH: USA. ACGIH Threshold Limit Values (TLV)
ACGIH BEI
: ACGIH - Biological Exposure Indices (BEI)
JP OEL ISHL
: Japan. Administrative Control Levels
JP OEL JSOH
: Japan. The Japan Society for Occupational Health. Recommendation of Occupational Exposure Limits
JSOH: Occupational exposure limits based on biological monitoring(JSOH).
ACGIH / TWA: 8-hour, time-weighted average
JP OEL ISHL / ACL: Administrative Control level
JP OEL JSOH / OEL-M: Occupational Exposure Limit-Mean
ADR: European Agreement concerning the International Carriage ofDangerous Goods by RoadCAS
: Chemical Abstracts ServiceDNEL: Derived no-effect level
EC50: Half maximal effective concentration
GHS: Globally Harmonized System
IATA: International Air Transport Association
IMDG: International Maritime Code for Dangerous Goods
LD50: Median lethal dosis (the amount of a material, given all at
once, which causes the death of 50% (one half) of a group oftest animals)
LC50: Median lethal concentration (concentrations of the chemical in
air that kills 50% of the test animals during the observation
period)MARPOL: International Convention for the Prevention of Pollution fromShips, 1973 as modified by the Protocol of 1978
OEL
: Occupational Exposure Limit
PBT: Persistent, bioaccumulative and toxic
PNEC: Predicted no effect concentration
REACH: Regulation (EC) No 1907/2006 of the European Parliamentand of the Council of 18 December 2006 concerning the Registration, Evaluation, Authorisation and Restriction of Chemicals (REACH), establishing a European Chemicals Agency
SVHC: Substances of Very High ConcernvPvB: Very persistent and very bioaccumulative
The information contained in this Safety Data Sheet corresponds to our level of knowledge at thetime of publication. All warranties are excluded. Our most current General Sales Conditions shallapply. Please consult the product data sheet prior to any use and processing.
JP / EN

13 / 13