List of Dissertation Abstract （Environment and Natural Sciences
NameSupervisor

Title
Examination of controlling

NatsukoShinyaENDO

MATSUMOTO

factors in preparation of thepolymorphic forms of 2,5bis[bis(4-chlorobenzyl)amino]3,6-dicyanopyrazine dyeLife Sciences Course）

AbstractThe title dye exhibits crystal polymorphism with different color: yellow, yellowish orange, and red.
The thermally stable yellow form is easily crystallized from several solutions, whereas it is difficult tosurely crystallize the metastable yellowish- orange and red forms. The red form was frequentlyobtained from the mixed solution including hexane. We also found that the sample solution including
hexane exhibited solvatochromism. In this presentation, the occurrence of the metastable forms will
be considered on the basis of optical properties of this dye in various solvent mixtures.

Substituent effect on
Akiko KUBO

Kiyoshi
HONDA

intramolecular

Bicyclo[3.2.0]heptane skeleton is common structure in natural products some of those having[2+2]photocycloaddition

biological activity. Regioselective intramolecular [2+2]photocycloaddition of 2,4,9-trienes havingof acyclic trienes andα,β,γ,δ-unsaturated ester moiety for constructing the bicyclo[3.2.0]heptane ring system was achieved.

determination of the products
The purpose of our study is to control the size of gold nanoparticles by adjusting the pH andYojiro

Takashi

KODAMAAMEMIYA

Size-control of Gold
Nanoparticles Using
Hydroquinone

concentrations of gold ions and hydroquinone (HQ). As a result, the size of the gold nanoparticles
was found to depend on the pH or the concentrations of reagents. HQ dissociates protons dependingon the pH of the solution. These analysis showed that the size of gold nanoparticles is proportional tothe exponentiation of the product of dissociated HQ and gold ions concentration. In this study, we cancontrol the size of gold nanoparticles by controlling product of reagent concentration.

Characterization of novel defense
ShioriKazuyuki

gene inducers based on salicylic

SHIABTAHIRATSUKA

acid quantification using
bioluminescent bacteria

we aimed to construct a high-throughput system which is more convenient and capable of treating
multiple samples than the conventional salicylic acid quantification method, and examined a method
using multi-well plate and Arabidopsis sprouts.

Fluoride anion-promoted ring

Benzofurans are used as building blocks in the synthesis of wide range of bioactive compounds.

MayumiKiyoshi

contraction reaction of 3-silyl-Among the enormous synthetic methods of benzofuran, the ring contraction reaction is the useful

SUKEKAWAHONDA

2H-1-benzopyran to 2-method. Herein, we report the fluoride anion-promoted ring contraction reaction of 3-silyl-2H-1-

benzylbenzofuranbenzopyran to 2-substituted benzofuran under the mild conditions.

Kanako

KiyoshiTACHIHONDASynthesis of isoxazolidine
derivative and polysubstituted
indane derivatives

Indane motif is basic structure which is included in natural products. I tackle synthesis ofisoxazolidine derivative and polysubstituted indane derivatives.
Tropolone is the typical examples of non-benzenoid compounds which possess pronounced aromaticcharacter. 5-(4-N,N-dianisylamino)phenyltropolone as the D-A type dye for the solar cell element wasinvestigated the molecular structures, the absorption behavior, the redox properties, and theRyoHiroyuki

HASEGAWAOTANI

Synthesis and Properties of theTroponoid Dyes for DyeSensitized Solar Cells

photovoltaic properties. These properties were compared with 5-(4-N,Ndianisylamino)phenyithiophenyltropolone and 5-(4-N,N-dianisylamino)phenylethynyltropolone of Dp-A type dye. Furthermore, based on the comparison results of these, 5-(4-N,Ndianisylamino)phenyltropolone containing 2,5-diethynylthiophene linker, as the novel p-expanded
troponoid dye, was designed and synthesized. In addition, the absorption properties in the solid state,redox behavior, and the properties as dye sensitized solar cell element of this p-expanded troponoid
dye were investigated.
2,5-Diamino-3,6-dicyanopyrazine dyes have been expected to apply to organic photoluminescent

Optical properties of 2,5-materials because of their strong fluorescence in solids in addition to that in a solution state.

diamino-3,6-dicyanopyrazine

Orange or red crystals were obtained from the derivatives having phenyl substituents at ortho or para

SayumiShinyaHATANO

MATSUMOTO dyes having phhenyl benzyl
substituents

position of the dibenzylamino groups. In this presentation, the optical properties of these twoderivatives in solid state will be discussed in terms of their crystal structure obtained from single
crystal X-ray structure analysis.

Changes in structure andproperty of bisazomethine dye

TakayaShinyaMINAMIMATSUMOTO derivatives by temperaturechange or solvation

A bisazomethine dye having diethylamino groups undergoes a structural phase transition
accompanying the change of lattice size in a high temperature region and at the same time exhibits adynamic behavior. In the case of the dipropylamino derivative, the crystal color varies depending on
the presence or absence of the solvent in the crystal, and the color reversibly changes by heating,solvent immersion and vapor exposure.
In yeast cells, the concentrations of metabolites in glycolytic pathway are known to oscillate underYu

Takashi

KAWAKITAAMEMIYA

Study of microbial interactions

some conditions. In yeast populations, these glycolytic oscillations are known to synchronize by theby analyzing oscillations

concentrations of acetaldehyde and so on. It is expected that the synchronization of glycolytic

synchrony in glycolytic pathway

oscillations exhibits microbial interactions in metabolism. We quantified this interactions.

Yichen DU

Takashi
AMEMIYA

Analysis of Glycolyticoscillations and synchronization
by a mathematical model

In this study, we have created a new glycolysis model based on three variables. The population
behavior of the cells is studied by simulations. Our results demonstrate that synchronicity depends on
membrane permeability and cell density, the mechanism of Spatio-temporal pattern has been
investigated.