•This product is a pharmaceutical product approved under a Japanese law, the Law for
Ensuring the Quality, Efficacy and Safety of Drugs and Medical Devices, with a view to its
sale and use in Japan.
•Multilingual product information is a translation of the product labeling written in
Japanese and provided for your information only. It does not warrant that its contents andthe product itself conforms to laws and regulations in countries other than Japan.
•Multilingual product information is a tentative translation by the provider (or OurCompany), and may be modified or altered without notice.
•The provider (or Our Company) assumes no responsibility for any problems that occur due
to the contents of the multilingual product information.
You should read this written explanation before use. Please keep it so that you can read it when you need to.

For abdominal bloating and intestinal regulation

Newly designatedquasi-drug

Rappa Intestinal Regulator BF
protects you from stomach discomfort and helps maintain good digestion[Features]• It accelerates absorption and excretion of gas accumulated in the digestive system.

With defoaming action of dimethylpolysiloxane, it accelerates absorption and excretion of gas
excessively accumulated in the stomach and intestines.

• A combination of 3 kinds of lactobacilli produces beneficial effects ofcontrolling intestinal function.

A well-balanced combination of 3 kinds of lactobacilli including lactomin (E. faecalis and L.
acidophilus) and Bifidobacterium bifidum produces lactic and acetic acids by increased good bacteria
in the small and large intestines. It inhibits the propagation of bad bacteria and produces beneficial
effect of controlling intestinal function.

• Easy-to-swallow fine granules

Rappa Intestinal Regulator BF has a slightly sweet flavor and comes as easy-to-swallow fine granules.
It can be used with confidence by anyone from children 3 years or over to the elderly.

• This medicine is in an individual aluminum package which is convenient forcarrying around.

[Precautions]
When not to use the product[If you do not follow these instructions, the current symptoms may worsen, or adverse
reactions/incidents are more likely to occur.]This product should not be taken by the following persons.
Patients who have had an allergic symptom (rash, redness, itching, etc.) to this drugConsultation
1. The following persons should contact a physician, pharmacist, or registered salesperson for aconsultation before administration.
(1) Patients undergoing medical treatment from a physician(2) Patients or their family with a predisposition to allergic diseases(3) Patients who have experienced allergic symptoms associated with drugs or cosmetics, etc.
2. When symptoms do not improve even after taking this medicine for about 2 weeks, stop taking thismedicine and consult a physician, pharmacist or registered salesperson, being sure to take thispackage insert (instruction leaflet) with you.

[Indications]
Intestinal regulation (regulation of stool), feeling of fullness in the abdomen, soft stool and constipation[Dosage and Directions]
Take the following dosages with cold or warm water within 30 minutes after a meal.
One dose Daily doseAge
1 packAdult (15 years and older)
2/3 pack
11-14 years of age
1/2 pack
8-10 years of age
3 times
1/3 pack
5-7 years of age
1/4 pack
3-4 years of age
Do not use
Under 3 years of age[Dosage and Administration Precautions](1) Follow the dosage and directions.
(2) When allowing children 3 years old andover to take the medicine, a guardianmust be present, and caution must be
exercised to prevent them from taking an
incorrect dose.

[Ingredients and Contents]
Every 3 packs (maximum daily adult dosage) include the following ingredients:
Active IngredientsContents

E. faecalis
18 mg
L. acidophilus

Proliferates in the small intestine and produces
lactic acid to inhibit pathogenic bacteria, thereby
maintaining a normal intestinal flora*.

24 mg

Dimethyl polysiloxane

180 mgAccelerates absorption and excretion of gas inthe digestive system and eliminates feeling ofabdominal bloating.

Antifoaming

Bifidobacterium bifidum

Mainly inhabits the large intestine as the mostbeneficial bacterium, and produces lactic acidand acetic acid to inhibit pathogenic bacteria,
thereby regulating the intestines.

Intestinal regulation

LactominEffect
Proliferates rapidly in the small intestine andacts to normalize the disordered intestinal flora*caused by loose stools or constipation.

[Inactive ingredients] Magnesium aluminometasilicate, lactose, white sugar, methyl cellulose,
polysorbate 80, sorbitan fatty acid ester, anhydrous silicic acid and talc.
*The intestinal flora is a group of bacteria which number more than 100 trillion and fall into 100 different categories
inhabiting the human intestines. In a healthy individual, a favorable balance is maintained between the beneficial
and the pathogenic bacteria in the intestines. However, when suffering from diarrhea, constipation, irregular diet,stress, or in the elderly, the pathogenic bacteria increases, resulting in an imbalance in the intestine flora.

[Precautions for storage and handling](1) Keep out of reach of children.
(2) Do not transfer the medicine to a different container. (It may lead to misuse or alter the quality of the drug.)(3) Store in a cool, low-humidity place away from direct sunlight.
(4) Do not use after the use-by date indicated on the package.
(5) When only using part of one pack of this medicine, close the package tightly by folding the opening,
store in a cool and dry place, and take the remainder within 2 days.

Marketing authorization holder
3-34-14, Uchihonmachi, Suita, Osaka, Japan 564-0032

Technical partner

Kissei Pharmaceutical Co., LTD.
19-48, Yoshino, Matsumoto, Nagano
AS· GL5030310201-4