switchSENSE®

WEBINAR

heliX® – a next generation
modular biosensor
for interaction andconformational analysis
You are cordially invited to a scientific webinar presenting
dynamicBIOSENSORS’ novel switchSENSE® measurementtechnology.
CBI ANNUAL MEETING 2020 ONLINE

Tuesday, October 27 at 01:00PM / Session ES-05

The scientific presentation will highlight the broad
range of applications of the switchSENSE® technologythat is supported by the recently launched heliX® lineof biosensor instruments, that pushes the boundaries
of what has been possible in biosensing to help you
do more:•Analysis of binding kinetics and molecular conformations in one measurement.

•Screening of conformational changes de novo by
real-time conformation referencing.

•Resolving the fastest kinetics with confidence
using advanced microfluidics and 10 ms data collection, and taking advantage of improved signal

stability for the characterization of high-affinity
binders in long dissociation measurements.
•Two-color single-photon counting fluorescence
detection for femto-molar sensitivity and the indepth analysis of bispecific binders.

•Effortless sensor functionalization and ad-vanced ligand density control with the new AdapterChip.

heliX® is based on a modular technical design and fea-tures an automatic chip-loader in conjunction with a384 well plate compatible autosampler, allowing you
to scale-up throughput to thousands of samples perday.

The Speaker I Ulrich Rant, PhD
Uli is a co-founder and CEO of Dynamic Biosensors GmbH, a Munich based biotech
venture company, which commercializes novel technologies in the field of biomolecular interaction analysis (switchSENSE®). Following its market entry in 2014, Uli
oversees the company’s activities in the continuous development and marketing ofpioneering nano-analytical instruments and biochips, focusing on growing Dynamic Biosensor’s business in EU, US, and Asia.

www.dynamic-biosensors.com

DISCOVER
MOLECULAR
INTERACTIONS
Kinetics – Affinity – Avidity
Conformational Changes
Thermodynamics

Webinar on Oct. 27 / 01:00PM
Introducing

the first modular
biosensor system.
Scalablethroughput

High performanceswitchSENSE® sensing

Easy-to-use
heliOS software

Up to thousands of samples
per day.

Each module with two-color
detection and four signals,
fM sensitivity.

Add modules to any networkby plug-and-play.

[384 well plate autosampler andautomatic 5 chip loader] x N
Combine as many autonomous
modules as you need to a scalable heliOS network.

Advanced microfluidics, kinetics with 10 ms resolution.

Control and monitor runs fromanywhere.

Conformation analysis bymolecular friction measurement.

About the technology
switchSENSE® is an automated, fluorescence-based biosensor chip technology that employs electrically actuated DNA

nanolevers for the real-time measurement of binding kinetics (k , k ) and affinities (with K values down to the fM range).
a dD
The platform offers an automated ligand density control, which allows to conveniently discriminate between affinity andavidity in one single assay. Interactions between proteins, DNA/RNA, and small molecules can be detected with femtomolar sensitivity. At the same time, protein sizes are analyzed and conformational changes as well as melting transitions(T ) can be measured using minimal amounts of sample.
MDKSH ジャパン株式会社

テクノロジー事業部門

科学機器部〒 143-0006 東京都大田区平和島 6-1-1 東京流通センター AE5-7（ショールーム）
Phone: 03-3767-4510, Fax: 03-3767-4569
Email: tp.labtyo@dksh.com

www.dynamic-biosensors.com