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日
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免
疫
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録

第

51

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2 022

日本免疫学会総会・学術集会記録
The 51st Annual Meeting of The Japanese Society for Immunology

第 51 巻Program

Kumamoto-Jo Hall

December 7 (Wed.)

熊本城ホール

8 (Thu.)

プ
ロ
グ
ラ
ム

9 (Fri.)

特定非営利活動法人

日本免疫学会Proceedings of the Japanese Society for Immunology (JSI)Vol. 51, 2022
ISSN 0919-1984

The 51st Annual Meeting of
The Japanese Society for Immunology
December 7– 9, 2022
Kumamoto-Jo Hall
Hybrid Format

President
Akihiko Yoshimura (Keio University School of Medicine)

Vice Presidents
Toshiaki Ohteki (Medical Research Institute, Tokyo Medical and Dental University)
Masayuki Amagai (Keio University School of Medicine)
Koichi Fukunaga (Keio University School of Medicine)
Takanori Kanai (Keio University School of Medicine)
Yutaka Kawakami (School of Medicine, International University of Health and Welfare)
Tsutomu Takeuchi (Keio University School of Medicine)

Program Committee, JSI(~31/12/2022)

Miyuki Azuma

Shohei Hori

Kiyoshi Takeda*

Koji Yasutomo

Toshinori Nakayama

Kazuko Shibuya

Keiko Udaka(~31/12/2024)

Sachiko Miyake*Chair

Program Committee for the Annual Meeting
Yoko Hamazaki
Kenji Kabashima
Yumiko Oishi

Kenya Honda
Masato Kubo
Kazuko Shibuya

1

Masaru Ishii
Atsushi Kumanogoh

The 51st Annual Meeting of the Japanese Society for Immunology
Congress Secretariat
c/o A & E Planning, Co., Ltd.
6th floor, Shin-Osaka Grand Bldg., 2-14-14,
Miyahara, Yodogawa-ku, Osaka, 532-0003, Japan
TEL : +81-6-6350-7163
E-mail : jsi2022@aeplan.co.jp

複写される方へ
特定非営利活動法人 日本免疫学会では、複写複製および転載複製に係る著作権を学術著作権協会に委託しています。当該利⽤をご希望の⽅は、学術著作権協会（https://www.jaacc.org/）が提供している複製利⽤許諾システムもしくは転載許諾システムを通じて申請ください。
権利委託先： 一般社団法人学術著作権協会（https://www.jaacc.org/）

2

COVID-19 Infection Control Measures

The 51st Annual Meeting of the Japanese Society for Immunology

The 51st Annual Meeting of the Japanese Society for Immunology places utmost importance on the safety
and security of all who are involved: participants, organizers, and staff, and takes the following measures.
We would like to ask for your understanding and cooperation.

Basic guidelines on COVID-19 infection control
We will follow measures set by Kumamoto-Jo Hall based on policies of the Kumamoto prefectural
government to prevent spread of COVID-19.

Request to visitors
Please refrain from coming to the meeting venue if you don’t feel well.
Any person having a fever, cough, pain in the throat, feeling of malaise or breathing problem on the day ofthe meeting is not allowed in the meeting venue.

Practice Social Distancing
Please try to practice social distancing. Mask is not obligatory outside or at the place where you can makeenough distance from others. However, please wear a mask if you feel it is necessary.

Infection Control
Please try to cooperate us to protect you and all the others who participate and engage in the 51st Annual
Meeting of the Japanese Society for Immunology.

Please wear a mask when you talk and discuss with others.
Mask is not obligatory outside or at the place where you can makeenough distance from others.

Please use hand sanitizers placed near entrances of buildings or rooms
often.
Please use them every time you enter or exit.

3

Program of The Japanese Society for
Immunology (JSI)Vol. 51
Contents
General Information for Annual Meeting 1

Conference Program
Overview Talks (OT01-OT16) 

27

Symposia (S01-S16) 

33

Workshops (WS01-WS31) 

45

Posters (WS01-WS31) 

85Awards Ceremony and Lectures 

157

Technical Seminars (T01-T09) 

163

Clinical Seminars (C01-C12, CE01) 

169

Clinical Evening Seminar (CE01) 

175

Afternoon Seminars (A01-A02) 

179

Evening Seminars (E01-E07) 

183

Young Academy Program 

189

Information for JSI Members 

193

Author Index 

196

Acknowledgements 

211

5

The 51st Annual Meeting of the Japanese Society for Immunology
Program at a glance
December 7 (Wed.), 2022
Building / Room

Program
8
Room Number

30

9

30

10

30

11

30

12

30

OT01 S01
4F

Main HallE
J Immune response against SARS-CoV-2 will
be discussed. Sponsored by International
Immunology

Room A

OT02 S02
2F

Civic Hall

Conference Room
A1

3F

OT03 S03

E
J Perspectives of synthetic biology forcancer immunology

C01

OT04 S04

C02

Conference Room
A3

Room E

OT05 S05

T02

OT06 S06

E
J From Pathology to Physiology:
Understanding immune system throughhuman immune-mediated disorders

T03

9:00

C03

Room G

Conference Room
D1·D2

Room H

Conference Room
E1·E2

Room IJ
MSD K.K.

J
HorizonDiscovery K.K.

E
J Immune tolerance and regulation: toward acomprehensive understanding of immune andtissue homeostasis : DGFI-JSI Joint Session

8:30

11:30

Exhibition HallA·B

J
TOMY DIGITALBIOLOGY CO., LTD.
J
Janssen Pharmaceutical
K.K. / Mitsubishi Tanabe
Pharma Corporation

T04
11:45

9:00

1F

12

J
CHUGAI
PHARMATICAL CO.,LTD.

E
J Introduction to Innovative Science for"Resolution of Inflammation" : SFI-JSI
Joint Session

Room F

Conference Room
C1·C2

J
Sony
Corporation

J Non-immune cell immunology :JCR-JSI Joint Session

Room CRoom D

Conference Room
A4

T01

Room B

Conference Room
A2

11:50

E

Equipment
Exhibition

Equipment Exhibition

Poster

6

J
Standard
BioTools K.K.

12:45

13

OT | Overview Talk

S |Symposium

C | Clinical Seminar

T | Technical Seminar

WS |Workshop

A | Afternoon Seminar

E in English

J in Japanese

14

30

30

15

30

E
Special Guest Award Ceremonyand Lectures
Kumamon

A1

14:25

J

15:25

E | Evening Seminar
17

30

30

18

19

30

WS1

E
T cell development(thymus and homeostasis)

WS2

30

20

21

30

Welcome
Reception
18:45

E

19:15

Anti-tumor
Effectors, Ag
presentation

TOMY DIGITALBIOLOGY CO.,LTD.
12:55

16

Live Streaming Programs

13:55

WS3

E01

E

Infection and
Immunity I

WS4

J

Cruising in the cell
[Moderna Japan Co., Ltd]

E02

E

J

Dendritic cells andmacrophages-1:
Immune regulation anddisease perspectives

臓器間ネットワークによる個体レベルでの恒常性維持機構の解明と代謝疾患制御

WS5

E03

[Moderna Japan Co., Ltd]J
Addressing the threat ofemerging viral infections

E
Innate lymphocytes[Moderna Japan Co., Ltd]

WS6J
Clinical
Evening Seminar:
Eisai Co., Ltd.

E

Autoimmune
diseases-Tissue specific-

WS7

19:30

E

Mucosal-Skin
Immunity

WS8

E

Anti SARS-CoV-2
immune responses andAntibody producers

:45

WS9
15:30

E
Molecular andcellular diversity ofallergic disease

16:45

18:30

Equipment Exhibition
17:00

17:45

E
E
Poster Discussion Poster Discussion(Odd No.) (Even No.)

7

20:45

The 51st Annual Meeting of the Japanese Society for Immunology
Program at a glance
December 8 (Thu.), 2022
Building / Room

Program
8
Room Number

4F

Main Hall

Room A

2F

Civic Hall

Room B

Conference Room
A1

3F

Room D

Conference Room
A3

Room E

Conference Room
D1·D2

Room H

Conference Room
E1·E2

Exhibition Hall
A·B

30

11

30

12

OT08 S08

C05

OT09 S09

C06

OT10 S10

T05

OT11 S11

C07

12

J
ASAHI KASEIPharmaE
J Recent Advances in Allergic Research :JSI-JSA Joint Session
E
J Advances in research of innate immune sensor
and diseases : US-Japan Immunology Program
Co-organized Session

J
Pfizer Japan Inc

J
BeckmanCoulter K.K.
J
DAIICHI SANKYOCOMPANY, LIMITEDE
J Single-cell technologies for System
Immunology in a New Era
9:00

30

J
Takeda Pharmaceutical
Company Limited

E
J Neuro-immune and inflammatoryinteraction : DGFI-JSI Joint Session

11:30

C08

J
Otsuka PharmaceuticalCo., Ltd.

T06

J
Thermo Fisher
Scientific

T07
Room I
9:00

1F

10

C04

8:30

Room G30EJ Recent advances in immunologicalmemory : ASI-JSI Joint Session

Room F

Conference Room
C1·C2

9

OT07 S07

Room C

Conference Room
A2

Conference Room
A430

Equipment
Exhibition

11:45

Equipment Exhibition

Poster8

J
SARTORIUS
JAPAN K.K.

12:45

2:45

13

A2

OT | Overview Talk

S |Symposium

C | Clinical Seminar

T | Technical Seminar

WS |Workshop

A | Afternoon Seminar

E in English

J in Japanese

14

30

15

WS10

J

30

E

T cell function anddiseases-1 (Diseasemodels and SARSCoV-2)

Nippon Becton
Dickinson
Company, Ltd.
12:55

30

13:55

WS11

17

30

30

18

30

19

20

30

Young Academy
ProgramE
Mucosal and Skin
Surface Barrier

E04

E

WS20

E05

J
mRNA therapeutics:
Present and futureJ
HD Video Recorderof the Cell

WS13

E
B cell Development
and Activation

WS21

Molecular and cellular
diversity of allergic
diseases (II)

ヒト肝臓オルガノイドを用いた代謝・
炎症性肝疾患研究

WS14

E
Innate immunity (1)Innate inflammationand disease

WS22

E07

WS15

E

WS23

E

WS24

WS17

[Moderna Japan Co., Ltd]

E06

E

E

E

15:20

[Moderna Japan Co., Ltd]
18:45

E
Human Immunology(Immunointervention)
E

E

Cytokines andChemokines-2
15:30

J

老化に伴う慢性炎症病態と免疫Hematopoiesis
and Immune
Environment

WS25

J

[Moderna Japan Co., Ltd]

Toleranceand Immune
suppression-2

Cytokines andChemokines-1

20:05[Moderna Japan Co., Ltd]E

Dendritic cells andmacrophages-2:
Myeloid cell linage andtheir differentiation

Toleranceand Immune
suppression-1

16:45

18:25

Equipment Exhibition
16:55

21

J

E
T cell function
and diseases-2(Disease models)

Infection and
Immunity II

WS16

30

WS18

WS19

Autoimmune
diseases-Systemic-

14:05

E | Evening Seminar

E

Tumor
Immunotherapy

WS12

16

Live Streaming Programs

17:40

E
E
Poster Discussion Poster Discussion(Odd No.) (Even No.)

9

20:00

21:15

The 51st Annual Meeting of the Japanese Society for Immunology
Program at a glance
December 9 (Fri.), 2022
Building / Room

Program
8
Room Number

4F

Main Hall

Room A

2F

Civic Hall

Room B

Conference Room
A1

Room C

3F

Conference Room
A2

Room D

Conference Room
A3

Room E

Conference Room
A4

30

1F

Exhibition Hall
A·B

30

10

30

11

30

12

OT12 S12

C09

OT13 S13

T08

OT14 S14

C10

OT15 S15

C11

OT16 S16C12E
J The impact of aging and senescenceon Immunity : US-Japan Immunology
Program Co-organized Session

E
J Recent advances in clinical applicationof cytokine/JAK research : KAI-JSI Joint
SessionE
J Recent Advances in immunometabolism

9:00

11:30

9:00

11:45

Room G

Equipment
Exhibition

Equipment Exhibition

Poster10

J
Nippon Becton Dickinson
Company, Ltd.
JONO PHARMACEUTICAL
CO., LTDJ
AbbVie GK

J
Specialty Care
Medical, Sanofi K.K.

E
J Microbiota and the host immune system :US-Japan Immunology Program
Co-organized Session

Room F

30

J
Novartis
Pharma K.K.

E
J Developmental branching and interplay
between innate and adaptive immunity :DGFI-JSI Joint Session

8:30

Conference Room
C1·C2

9

T09

J
Leica
Microsystems K.K.
12:45

13:00

45

13

OT | Overview Talk

S |Symposium

C | Clinical Seminar

T | Technical Seminar

WS |Workshop

A | Afternoon Seminar

E in English

J in Japanese

30

14

30

15

30

16

30

E | Evening Seminar
17

30

WS26

E
T Cell activation
and responses(human and Vitro)

WS27

E
Tumor
Microenvironment,
Metabolism

WS28

E

Infection and
Immunity III

WS29

E

Dendritic cells andmacrophages-3:
Regulation of cytokine
production, pathogenesis

WS30

E
Innate immunity (2)Innate recognitionand signaling

WS31

E

Autoimmunity
13:00

14:15

16:00

Equipment Exhibition
14:30

Live Streaming Programs

15:15

E
E
Poster Discussion Poster Discussion(Odd No.) (Even No.)

11

18

30

19

30

20

30

21

WS 一覧
Session Workshop (Oral)

Workshop (Poster)Discussion Discussion
Time
Time
(odd number) (even number)

The numberofpresentations

Date
&
Time

Room

Presentation
No.

WS01 T cell development (thymus and homeostasis)

7

December 7 (Wed.)
15:30-16:45

Room A

WS01-01 ～WS01-21

December 7
17:00-17:45(Wed.)

17:45-18:30

WS02 Anti-tumor Effectors, Ag presentation

8

December 7 (Wed.)
15:30-16:45

Room B

WS02-01 ～WS02-28

December 7
17:00-17:45(Wed.)

17:45-18:30

WS03 Infection and Immunity I

9December 7 (Wed.)
15:30-16:45

Room C

WS03-01 ～WS03-26

December 7
17:00-17:45(Wed.)

17:45-18:30

8

December 7 (Wed.)
Room D
15:30-16:45

WS04-01 ～WS04-21

December 7
17:00-17:45(Wed.)

17:45-18:30

WS05 Innate lymphocytes

10

December 7 (Wed.)
15:30-16:45

Room E

WS05-01 ～WS05-22

December 7
17:00-17:45(Wed.)

17:45-18:30

WS06 Autoimmune diseases -Tissue specific-

8

December 7 (Wed.)
15:30-16:45

Room F

WS06-01 ～WS06-21

December 7
17:00-17:45(Wed.)

17:45-18:30

WS07 Mucosal-Skin Immunity

9

December 7 (Wed.)
Room G
15:30-16:45

WS07-01 ～WS07-22

December 7
17:00-17:45(Wed.)

17:45-18:30

No.

WS04

Title

Dendritic cells and macrophages-1:
Immune regulation and disease perspectives

Date

WS08

Anti SARS-CoV-2 immune responses andAntibody producers

12

December 7 (Wed.)
15:30-16:45

Room H

WS08-01 ～WS08-22

December 7
17:00-17:45(Wed.)

17:45-18:30

WS09

Molecular and cellular diversity of allergic
disease9

December 7 (Wed.)
15:30-16:45

Room I

WS09-01 ～WS09-20

December 7
17:00-17:45(Wed.)

17:45-18:30

WS10

T cell function and diseases-1(Disease models and SARS-CoV-2)

7

December 8 (Thu.)
14:05-15:20

Room B

WS10-01 ～WS10-25

December 7
17:00-17:45(Wed.)

17:45-18:30

WS11 Tumor Immunotherapy

10

December 8 (Thu.)
14:05-15:20

Room C

WS11-01 ～WS11-26

December 8
16:55-17:40(Thu.)

17:40-18:25

WS12 Infection and Immunity II

8December 8 (Thu.)
14:05-15:20

Room D

WS12-01 ～WS12-25

December 8
16:55-17:40(Thu.)

17:40-18:25

WS13 B cell Development and Activation

11

December 8 (Thu.)
14:05-15:20

Room E

WS13-01 ～WS13-19

December 8
16:55-17:40(Thu.)

17:40-18:25

Innate immunity (1)Innate inflammation and disease

7

December 8 (Thu.)
14:05-15:20

Room F

WS14-01 ～WS14-18

December 8
16:55-17:40(Thu.)

17:40-18:25

WS15 Autoimmune diseases -Systemic-

9

December 8 (Thu.)
14:05-15:20

Room G

WS15-01 ～WS15-20

December 8
16:55-17:40(Thu.)

17:40-18:25

WS16 Tolerance and Immune suppression-1

10

December 8 (Thu.)
14:05-15:20

Room H

WS16-01 ～WS16-19

December 8
16:55-17:40(Thu.)

17:40-18:25

WS17 Cytokines and Chemokines-1

10

December 8 (Thu.)
14:05-15:20

Room I

WS17-01 ～WS17-16

December 8
16:55-17:40(Thu.)

17:40-18:25

T cell function and diseases-2(Disease models)8

December 8 (Thu.)
15:30-16:45

Room B

WS18-01 ～WS18-25

December 8
16:55-17:40(Thu.)

17:40-18:25

9

December 8 (Thu.)
15:30-16:45

Room C

WS19-01 ～WS19-23

December 8
16:55-17:40(Thu.)

17:40-18:25

WS14

WS18

WS19 Mucosal and Skin Surface Barrier
WS20

Dendritic cells and macrophages-2:
Myeloid cell linage and their differentiation

8

December 8 (Thu.)
15:30-16:45

Room D

WS20-01 ～WS20-21

December 8
16:55-17:40(Thu.)

17:40-18:25

WS21

Molecular and cellular diversity of allergic
diseases (II)9

December 8 (Thu.)
15:30-16:45

Room E

WS21-01 ～WS21-21

December 8
16:55-17:40(Thu.)

17:40-18:25

WS22 Hematopoiesis and Immune Environment

10

December 8 (Thu.)
15:30-16:45

Room F

WS22-01 ～WS22-25

December 9
14:30-15:15(Fri.)

15:15-16:00

WS23 Human Immunology (Immunointervention)

9

December 8 (Thu.)
15:30-16:45

Room G

WS23-01 ～WS23-16

December 9
14:30-15:15(Fri.)

15:15-16:00

WS24 Tolerance and Immune suppression-2

10

December 8 (Thu.)
15:30-16:45

Room H

WS24-01 ～WS24-20

December 9
14:30-15:15(Fri.)

15:15-16:00

WS25 Cytokines and Chemokines-2

10

December 8 (Thu.)
15:30-16:45

Room I

WS25-01 ～WS25-17

December 9
14:30-15:15(Fri.)

15:15-16:00

T Cell activation and responses(human and Vitro)

9

December 9 (Fri.)
13:00-14:15

Room B

WS26-01 ～WS26-24

December 9
14:30-15:15(Fri.)

15:15-16:00

WS27 Tumor Microenvironment, Metabolism

8

December 9 (Fri.)
13:00-14:15

Room C

WS27-01 ～WS27-27

December 9
14:30-15:15(Fri.)

15:15-16:00

WS28 Infection and Immunity III

8

December 9 (Fri.)
13:00-14:15

Room D

WS28-01 ～WS28-25

December 9
14:30-15:15(Fri.)

15:15-16:00

WS26

WS29

Dendritic cells and macrophages-3:
Regulation of cytokine production, pathogenesis

8

December 9 (Fri.)
13:00-14:15

Room E

WS29-01 ～WS29-24

December 9
14:30-15:15(Fri.)

15:15-16:00

WS30

Innate immunity (2)Innate recognition and signaling

7

December 9 (Fri.)
13:00-14:15

Room F

WS30-01 ～WS30-20

December 9
14:30-15:15(Fri.)

15:15-16:00

8

December 9 (Fri.)
13:00-14:15

Room G

WS31-01 ～WS31-20

December 9
14:30-15:15(Fri.)

15:15-16:00

WS31 Autoimmunity

12

Access

The 51st Annual Meeting of the Japanese Society for Immunology

Kumamoto-Jo Map

Domestic Flight
Haneda (Tokyo)

About

1 hr 35 min

Narita (Chiba)

About

1 hr 45 min

Komaki (Nagoya)

About

1 hr 20 min

Chubu (Nagoya)

About

1 hr 20 min

Itami (Osaka)

About

1 hr 05 min

Naha (Okinawa)About

1 hr 25 min

About 46 min by Bus

Aso
Kumamoto
AirportKumamoto-jo
Hall

ShinkansenTokyo

5 hr 45 min

Nagoya3 hr 50 min

Shin-Osaka

2 hr 58 min

Shin-Kobe

2 hr 45 min

Okayama
Hiroshima
HakataKagoshima

2 hr 15 min
1 hr 37 min
33 min

12 min by City Tram

JRKumamoto
Station43 min13

Kumamoto-jo
HallFloor Plan

The 51st Annual Meeting of the Japanese Society for Immunology

Kumamoto-Jo Hall

1F 1F
Exhibition Hall B

Poster / Equipment
Exhibition
Exhibition Hall A・B
Exhibition Hall A

Foyer
1F-2F

2F

2F

3F
B１

B２

Conference Room

シビックホールB

Room B
Civic Hall A・B
Room F

A４ Room
Conference

Room
E
A３

Registration/ Cloak
E２
Entrance Lobby
H２

E１

H１

D２

A3

D１

Room D

C２

A2

C１

Foyer

A２ Room
Conference

G２

1F-2F

Conference Room

D1・2

G１
F２
F１
授乳室
救護室

Room
C
A１

Room H

Entrance Lobby

Conference Room

2F-3F

E1・2

2F-3F-4F

A4

Civic Hall A

Room I

B３

3F-4F

Room G

Conference Room

311

C1・2

Conference Room

2F-3F

A1

PC Preview
2F-3F

14

4F
4F-5F

Foyer

Exhibition Hall A・B
Exhibition Hall A

Floor Plan

The 51st Annual Meeting of the Japanese Society for Immunology

Foyer
1F-2F

2FHallKumamoto-Jo

3F3F

4F
B１

B２

Room I

B３

シビックホールB

Room B
Room F

Registration / Cloak
Entrance Lobby

E２

Civic Hall A

Room
E
A３

H２

E１

H１ Entrance Lobby

D２

Conference Room

G２

D１

A3

Foyer

Room D

D1・2

F２
F１

C１
2F-3F

1F-2F

3F-4F

授乳室

Room G
救護室

Conference Room

311

Room
C
A１

Room H

Conference Room

G１

C２

A２ Room
Conference

A2

2F-3F-4F

E1・2

Civic Hall A・B

A４ Room
Conference

A4

Conference Room

C1・2

Conference Room

2F-3F

A1

PC Preview

4F

m

2F-3F

4F
4F-5F

Foyer

4F-5F

om H

rence Room

D1・2

3F-4F

G

Room

2

Room A
Main Hall

view

401
402
403

15

Equipment Exhibition

The 51st Annual Meeting of the Japanese Society for Immunology

PosterExhibitors List
1 Veritas Corporation
2 RIKEN BioResource Research Center
3 NBRP Pathogenic eukaryotic microbes
4 Luminex Japan Corporation Ltd.
5 Air Liquide Japan G.K.
6 CSCRIE CORPORATION
7 Merck Ltd. Japan
8 miltenyi Biotec K.K.
9 Kyudo Co., Ltd.
10 FUJIFILM Wako Pure Chemical Corporation
11 Beckman Coulter K.K.
12 Thermo Fisher Scientific
13 InvivoGen Limited
14 nacalai tesque
15 Kiko Tech Co., Ltd.
16 GenScript Japan
17 Japan SLC, Inc.
18 SYSMEX CORPORATION
19 Lonza K. K.
20 DNA Chip Research Inc.
21 Axion BioSystmes Japan22·28 TOMY DIGITAL BIOLOGY CO., LTD.
23 IWAI CHEMICALS COMPANY LTD.
24 Standard BioTools K.K.
25 Horizon Discovery K.K.
26 ACROBIOSYSTEMS CO.,LTD.
27 SARTORIUS JAPAN K.K.
29 10x Genomics / SCRUM Inc.
30 QuidelOrtho
31 Sino Biological Inc
32 NanoString Technologies, Inc.
33 TechnoSuruga Laboratory Co.,Ltd.
34 Shanghai Model Organisms Center (USA), LLC
35 Tokyo Ohka Kogyo Co., Ltd.
36 Sony Corporation
37 Nippon Becton Dickinson Company, Ltd.

Kibou Project

Drink Service

Equipment
Exhibition

EV

16

ご案内
1．現地会場（熊本）での参加方法◆ オンラインで参加登録をされた方参加証（ネームカード）や領収書、参加証明書は、学術集会オンラインシステム「ONLINE CONF」
へログインのうえダウンロードしてください。ログインにはご自身で登録したメールアドレスとパス
ワードをお使いください。
ネームホルダーは、現地の受付付近でお受け取り下さい。
◆ 現地で当日参加申込をされる方

参加受付にて学術集会参加費（下記参照）をお支払いのうえ、ネームカードをお受け取りください。
ネームカードをご着⽤でない⽅の入場はお断りします。
〈当日参加費（後期登録）〉
正会員
14,000 円
学生会員 *
3,000 円学部学生会員 *無 料
非会員
17,000 円
非会員学生 *
7,000 円非会員学部学生 *無 料* 学部・大学院生は学生証の提示が必要です* お支払いは現金のみです〈参加受付開設時間〉
12 月 7 日（水）12 月 8 日（木）12 月 9 日（金）7：45 ～ 18：00
8：00 ～ 18：00
8：00 ～ 15：00◆ 名誉会員・功労会員

2 階 エントランスロビーの学会事務局デスクにお越しください。
名誉会員・功労会員の先生⽅には現地、オンライン参加に関わらず、事前に JSI 事務局よりオンライン視聴⽤の URL ＋ PW をご案内いたします。

2．オンラインでの参加方法
オンラインではオーバービュートーク、シンポジウム、テクニカルセミナー、クリニカルセ
ミナー、アフタヌーンセミナー、イブニングセミナーの発表が配信されます。ワークショッ
プ（口頭発表およびポスター）およびポスターの配信はいたしません。
◆ オンラインで参加登録をされた方学術集会オンラインシステム「ONLINE CONF」へアクセスし、抄録やオンライン配信をご覧ください。
領収書や参加証明書も「ONLINE CONF」よりダウンロードしてください。
17◆ 現地で当日参加申込をされた方 地で参加登録をした後、オンライン配信を視聴する場合は、参加証に学術集会オンラインシステ
現ム「ONLINE CONF」の ID と PW が記載さていますので、ホームページよりアクセスの上、オンライン配信をご覧ください。

3．オンデマンド配信について
 部のプログラムでは、会期中の発表を録画しオンデマンド配信いたします。
一
もう一度見たい講演や見逃した講演など、是非ご覧ください。
〈配信期間〉

プログラム実施の約 3 日後～ 2023 年 1 月 10 日（火）〈視聴方法〉

学術集会オンラインシステム「ONLINE CONF」へログインのうえご視聴ください。
〈配信するプログラム〉
Overview Talk、シンポジウム、イブニングセミナー：発表者の承諾を得た一部の発表を配信します。配信対象の発表は、プログラムページでアイコンを表示しています。
一般演題（Workshop/ 口頭発表）：配信はいたしません。
一般演題（ポスター）：配信はいたしません。

OD

4．入会手続きおよび年会費の納入
 本免疫学会に未入会の方は、学会事務局デスク（現地会場）にて入会できます。2023 年度会費お日よび未納年会費の納入も同所で受け付けます。また、学会ホームページでもお手続きできます。
入会金
年会費
		
		
		

国内正会員 海外正会員 国内学生会員 
海外学生会員 1,000 円
11,000 円
12,000 円
3,000 円
4,000 円

※一般演題の筆頭著者（発表者）は、2022 年度の会員（正会員、学生会員、功労会員、名誉会員に限ります）であることが義務付けられております。

5．プログラム、抄録集（プロシーディングス）
プログラムは、学術集会ホームページで公開し、また現地会場でも冊子を配布いたします。
会員は、抄録集（プロシーディングス）を PDF データ形式で学会ホームページの会員専用ページにて閲覧できます。閲覧にはご自身の会員番号（ID）とパスワードが必要です。
2022
年度会費を最近納入されたにもかかわらず、会員専用ページで閲覧できない際には学会事務局
へお問い合わせください。
非会員の方には 5,000 円（税込）にて Web 抄録集の閲覧 URL とパスワードを販売いたします。
必要な方は参加登録の際にお申込みください。現地会場で参加申込をする方は、学会事務局デスク
へお越しください。
18

6．授賞式・受賞講演
授賞式：12 月 7 日（水） 14:15 ～ 14:25 A 会場（メインホール）にて行います。
・日本免疫学会 功労会員表彰式
・日本免疫学会賞 授賞式
・日本免疫学会ヒト免疫研究賞 授賞式
・日本免疫学会女性免疫研究者賞 授賞式
・日本免疫学会研究奨励賞 授賞式
・International Immunology Outstanding Merit Award 授賞式
受賞講演：12 月 7 日（水）14：25 ～ 15：15 ※授賞式に引き続き行います。
日本免疫学会賞、日本免疫学会ヒト免疫研究賞、日本免疫学会女性免疫研究者賞 受賞講演

7．学術集会プログラム
本大会では以下のプログラムを実施します。
ウェルカムレセプション
	本学術集会では日本免疫学会の新しい 50 年の門出を祝し、ささやかながらウェルカムレセプ
ションの開催を大会初日に予定しております。事前申込不要・参加費不要です。
	現地会場にお越しの方は是非ご参加くださいませ。
アフタヌーンセミナー
	協力企業との密な連携のもと、次世代を担う免疫学研究者を育成するプラットホームの構築をめ
ざし、企業ならではの趣向を取り入れたセミナーです。
イブニングセミナー
	免疫学会の次の 50 年の第一歩として「未来の免疫学」と題し、「老化」「脳神経代謝」「再生」「合成生物学」「RNA 創薬」など今後免疫学の分野でも重要になってくるであろう領域について、本業として免疫を専門とされないその分野の第一人者をお招きし、わかりやすく講演していただく
セミナーです。演者の講演に加え、座長による研究成果と将来の夢について紹介があります。軽食も用意しておりますので、若い人たちの積極的なご参加を是非ともお願いします。
若手フォーラム「免疫学の未来」（免疫若手アカデミー共催）
	免疫学の未来を展望する若手座談会（フォーラム）を予定しています。当日は Web での参加も歓迎します。会場および zoom での質疑応答もあります。どんな研究をしたらよいか？どのような手法を用いるべきか？何を明らかにすべきか？将来のキャリアパスは？皆で語り合いましょう。
オーバービュートーク
	各領域の基礎知識、歴史と発展を系統的に紹介する入門者向けの教育講演です。オーバービュー
トーク終了後、休憩時間をはさまずシンポジウムに移ります。
シンポジウム	国内外の免疫の研究者による 16 テーマ（S01 ～ S16）の国際シンポジウムを開催します。
	演者の選考および形式については、プログラム委員会で指名した座長に一任いたしました。
	それぞれのシンポジウムが同時進行する形をとります。シンポジウム進行方法、各演者の講演時間などは全て座長に一任しております。
JSI-JSA Joint Symposium

19日本アレルギー学会とのジョイントセッションです。詳細はプログラムページをご確認ください。
JCR-JSI Joint Symposium
日本リウマチ学会とのジョイントセッションです。詳細はプログラムページをご確認ください。
ポスター、ワークショップ（口頭発表）
	一般演題は、すべての演題のポスター発表と一部の演題による口頭発表が行われます。口頭発表
と共にポスターでの活発な討論をお願いいたします。
	ポスター討論ではディスカッサーを設けますので、会員、参加者の皆様の熱のこもった討論、そしてさらなる交流・情報交換の場となることを期待しております。
ベストプレゼンテーション賞、ベストポスター賞
	各 Workshop、ポスターセッションでそれぞれ一件のベストプレゼンテーション賞、ベストポ
スター賞を選定する予定です。
ぜひ活発なディスカッションをお願いいたします。
ランチョンセミナー	テクニカルセミナー、クリニカルセミナーはランチョン形式で行います。お弁当の入手方法については、次項の「8. セミナー整理券」をご参照ください。
	講演の言語は「At a Glance」ページでご確認ください。
▶ テクニカルセミナー

 新の医学・生命科学関連試薬・技術・機材・器機等を使った実験法などや、アレルギー・免疫疾患・最癌・感染症研究に関連する最新の器機紹介を通じて、基礎研究・応用研究・開発研究の融合の場となるセミナーです。
▶ クリニカルセミナー

 薬品・生物学的製剤等による免疫疾患や感染症の診断や治療・予防の進展などをご紹介いた医
だくセミナーです。

8．セミナー整理券（ランチョンセミナー、イブニングセミナー）
 クニカルセミナー、クリニカルセミナー、イブニングセミナーで配布されるお弁当や軽食は、
テ「セミナー整理券」と引き換えにてお渡しいたします。「セミナー整理券」は以下のように配布いたします。
なお、お弁当の数には限りがあります。予めご了承ください。
      ◆

セミナー整理券発券デスク

 日お一人につき一枚、セミナー整理券を配布します。複数枚のお渡しはできませんのでご了承く
各ださい。
場
所：2 階 エントランスロビー
配布時間：各日 OPEN ～ 11:30 ※ 11:30 以降は各セミナー会場前で配布いたします      ◆

お弁当の引換開始時刻

 ミナー開始 15 分前より、各セミナー会場前でセミナー整理券とお弁当を引き換えのうえ、会場へ
セの入場を開始いたします。
※会場の状況、直前セッションの進行状況等により前後することがございます。
20

〈ご注意〉
・セミナー開始時刻までに来られない場合にはセミナー整理券は無効となり、整理券をお持ちでない方にご提供しますことをご了承ください。
・整理券をお持ちでなくてもセミナーを聴講することはできますが、余剰がない場合はお弁当の配布はございませんのでご了承ください。

9．機器・試薬等展示
 期中、大会会場内で機器・試薬展示を行います。休憩コーナー、ドリンクコーナーもご用意いた会しますので、是非ご来場ください。
また、出展企業より提供される景品が当たるスタンプラリーも実施します。豪華景品もご用意しておりますので、是非ご参加ください。

10．会員懇親会
 学術集会では会員懇親会を実施いたしません。ただし、1 日目の 18 時 45 分から 19 時 15 分に本
ウェルカムレセプションを行い、飲み物をご提供する予定です。

11．インターネット接続
 場内では WiFi をご利用いただけます（無料）。接続するための SSID とパスワードは、会場内で会掲示します。

12．学術集会講演会場における撮影・録音行為の規制について
学術集会講演会場（シンポジウム会場、
口頭発表会場、ポスター会場など、学会発表内容のある場所）
における撮影、録音行為を禁止いたします。ただし、学会が承認したものはその限りではありません。
こ れは、発表者の許可無く学会発表の撮影・録音がおこなわれることにより、論文未掲載の最新
データの発表が差し控えられるという現状を鑑みたものです。
会員の皆様の積極的かつ、活発な研究発表と討議がなされることを期待いたします。

21

General Information
1. On-site Participation (Kumamoto)◆Participants who registered online

Log into your account of ONLINE CONF, the online conference system, and download your meetingbadge and the receipt of the registration fee. You can log into the system with your email address andpassword you set. Badge holders are available at the Registration Desk.
◆

Participants who register on-site

Please come to the registration desk, pay registration fee below and receive a meeting badge.
Participants without wearing their meeting badges will not be allowed to enter the meeting site.
〈On-Site Registration Fees (Late)〉
Member:JPY 14,000
Student Member *:JPY 3,000
Undergraduate Student Member*:Free
Non-member:
JPY 17,000
Student Non-member*:
JPY 7,000
Undergraduate Student Non-member*:Free*Undergraduate and graduate students are required to show their student ID.
*We accept cash only.
〈Registration Desk opening hours〉
December 7 (Wed)7:45 - 18:00
December 8 (Thu)
8:00 - 18:00
December 9 (Fri)
8:00 - 15:00◆

Honorary members / Meritorious members

Please come to the JSI Secretariat Desk at Entrance Lobby, 2F.
Honorary and Meritorious members who attend on-site or virtually will receive the URL and password toview online programs from JSI secretariat prior to the meeting.

2. Online Participation
Overview Talks, Symposia, Technical Seminars, Clinical Seminars, Afternoon Seminars andEvening Seminars will be distributed online. Workshop (both oral and poster) will not be
distributed.
◆

Participants who registered online

Log into “ONLINE CONF”: the online meeting system, then you can browse abstracts and view lectures
online. A receipt of registration fee and certificate of attendance are downloadable from this system.

22         ◆Participants who registered on-siteAfter register on-site, you can view lectures online as well. ID and password to log into ONLINE CONF,
the online conference system, will be printed on your meeting badge. You can access to the system fromthe meeting website.

3. On-demand StreamingSome sessions will be recorded and available for on-demand streaming after the meeting.
You can view sessions which you want to view again, or you miss during the meeting.
〈Streaming Period〉
3 days after sessions to January 10 (Tue).
〈How to view〉
Log into “ONLINE CONF” and start viewing on-demand streaming sessions.
〈On-demand streaming sessions〉
Overview Talk / Symposia / Evening Seminars / Lectures will be available for on-demand
streaming with approval from those lecturers. Lectures available for on-demand streaming
are marked with the icon on the program page.
Regular presentations (Workshop/Oral): Not available for on-demand streaming
Regular presentations (Poster): Not available for on-demand streaming

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4. Application and Annual Membership Fee
You can join the JSI (the Japanese Society for Immunology) at the JSI desk on the meeting site. You canalso pay your membership fees at the JSI desk. For online participants, please visit the society website
to join the membership or pay membership fees.
Application fee

JPY 1,000
Annual Membership Fee Member (Domestic)
JPY 11,000
				Member (Overseas)
JPY 12,000				Student Member (Domestic) 
JPY 3,000				Student Member (Overseas) 
JPY 4,000*First Authors (Presenting authors) must be JSI members: Regular, Student, Meritorious and Honorary
members. However, foreign-registered authors residing outside Japan are excluded.

5. Meeting Program / Proceedings (Abstracts)
Digital version of Meeting Program will be available on the meeting website and printed version of
Meeting Program will be distributed to all participants on the meeting site.
Proceedings (abstracts) as a PDF file will be available at the website for JSI members. You need yourmembership ID and password to login to this website.
If you completed the payment of 2022 annual membership fee, but you cannot login to the website for
JSI members, please contact the JSI secretariat.
If you are not a JSI member, you can purchase ID and password to login to the website for JPY 5,000
through the meeting website in advance or the JSI Secretariat Desk on the meeting site.
23

6. Awards Ceremony & Lectures
Ceremonies: Wednesday, December 7, 14:15-14:25, Room A (Main Hall)· Commendation Ceremony of JSI Meritorious Member· JSI Award Ceremony· JSI Human Immunology Research Award Ceremony· JSI Women Immunologist Award Ceremony· JSI Young Investigator Award Ceremony· International Immunity Outstanding Merit Award Ceremony
Lectures: Wednesday, December 7, 14:25-15:15, Room A (Main Hall)
Lectures below will be held after the above Ceremonies.
· JSI Award Lecture· JSI Human Immunology Research Award Lecture· JSI Women Immunologist Award Lecture

7. Programs
The 51st JSI meeting will have following programs.
Welcome Reception  We would like to have a small celebration of the next 50 years of the Japanese Society for Immunology
and hold “Welcome Reception” on Day 1. No pre-registration nor participation fees are required. We
hope that all of on-site attendees will join us on this occasion.
Afternoon Seminars  Those seminars are held aimed at building platforms for developing Immunologists who are responsible
for the next generation in close collaborations with cooperative companies. Those are elaborate
seminars unique to the companies.
Evening Seminars  As a first step toward the next 50 years of the Japanese Society for Immunology, the evening
seminars entitled “Future of Immunology” will be held. We invite leading researchers whose coreareas of specialization are not Immunology but are the fields of study such as “Aging” “Brain, Nerve,
Metabolism” “Regeneration” “Synthetic Biology”, and ”mRNA drug discovery”, which will become
more important to the field of Immunology. Chairpersons of the seminars will be appointed among
young researchers, and they will be asked to speak about their research dreams.
Round-table discussion for young scientists  The round-table discussion for young researchers (forum) will be held to look toward the future of
Immunology. Refreshments will be served during the forum. We look forward to active participation ofyoung researchers in the forum.
Overview Talk  Overview talks held prior to each symposium are kind of educational lectures and especially forstudents or those who are not specialized in the topics.
S
ymposia  I nternational symposia on 16 topis (S01-S16) will be held by both domestic and overseas
immunologists. The program committee appointed chairs of symposia and left selection of speakers
to the discretion of those chairs.
  Some symposia will be conducted concurrently. Chairs decide how they lead their sessions andpresentation time of each speaker.
24

JSI-JSA Joint Symposium  The symposium will be held jointly with Japanese Society of Allergology. Refer to the program page fordetailed information.
JCR-JSI Joint Symposium  The symposium will be held jointly with Japan College of Rheumatology. Refer to the program page fordetailed information.
Workshop (Oral presentations and Poster)  All regular papers are to be presented at Poster session. Some of selected regular papers are to bepresented at Workshop as well. Discussers will join poster discussion. We hope that poster discussion
will be a great opportunity for active discussion, communication, and information exchange between
JSI members and non-members.
Best Presentation Award / Best Poster Award
The Best Presentation Award will be selected among presentations in Workshops and the Best Poster
Award will be selected among presentations in Poster sessions.
We hope you all engage active discussions.
Luncheon Seminars
  T here will be three types of sponsored seminars: Technical Seminars, Clinical Seminars and Afternoon
Seminars.
  Technical and Clinical Seminars will be held in the form of luncheon seminars. Please refer to “8.
Luncheon Seminar Ticket” for more information regarding Luncheon seminars.
  L
 anguage of each seminer can be found on “At a Glance” of the program page of our website.
◆ Technical Seminars
 T hose seminars aim to promote interaction between basic research, application research anddevelopment research through introducing experimental methods with latest life science related
regents, technologies, machines and equipment, or latest equipment for researching allergy,
immunological diseases, cancer, and infectious disease.
◆ Clinical Seminars
 T hose seminars aim to introduce developments of diagnosis, treatment and prevention of

immunological and infectious diseases caused by pharmaceutical and biological products.
◆ Afternoon Seminars
 T
 hese seminars aim to build a platform of development of immunologists who will be engaged in thenext generation through close cooperation with companies. Companies add fresh dimensions toseminars by their unique idea.

8. Luncheon Seminar Ticket (Luncheon Seminars)      A box lunch will be served for those has a Luncheon Seminar Ticket at both Technical and ClinicalSeminars. Please kindly note that number of tickets are limited. Tickets will be distributed as below:◆ Luncheon Seminar Ticket Desk
 O
 ne ticket for one person on a day. Ticket distribution is on the first come, first served basis. We are

not able to distribute more than one ticket to one person on a day.
 ocation: Entrance Lobby, 2FL T ime: OPEN-11:30 (After 11:30, you may receive a ticket in front of each session room if tickets arestill available)25

◆

Receiving a box lunch R edeem a ticket to receive a box lunch. You can receive it from 15 minutes before seminars begin in

front of each seminar room.
 * Starting time for receiving may be changed depending on previous seminar’s ending time.

〈 IMPORTANT〉
 · Please arrive at the seminar rooms before the start time. If you do not show up in the room by thestart time, your box lunch will be provided to another attendee who does not have a ticket.
· You can attend those seminars without tickets, however, a box lunch will not be served.

9. Commercial Exhibition – Exhibition of Machineries and Reagents      Exhibitions of machineries and reagents will be held. There will a resting space and drink service in the
exhibition space.
      If you collect stamps by visiting exhibition booths, you can get gifts provided by exhibitors. You havechance to win a special gift. Look forward to your participation in the stamp tally.

10. Get Together Party      Get together party will not be held this year. However, "Welcome Reception" will be held on Day 1,
18:45-19:15. Drinks will be served at the reception.

11. Internet access     Free Wi-Fi is available in the venue. The SSID and password to use Wi-Fi will be displayed in the venue.

12. Photographing and recording      Photographing and recording are prohibited in all sessions. However, photographing and recording bythose who have obtained the permission from the JSI may be granted.

26

Overview Talk

Program for Overview Talks
8:30 ~ 9:00, Wednesday, December 7
OD OT01 Overview Talk 01

Room A: Main Hall

Chairpersons: Hisashi Arase (WPI Immunology Frontier Research Center, Osaka University)
Saya Moriyama (National Institute of Infectious Diseases)

Overview of COVID-19 in Japan
Satoshi Kutsuna Graduate School of Medicine / Faculty of Medicine, Osaka University
8:30 ~ 9:00, Wednesday, December 7
OD OT02 Overview Talk 02

Room B: Civic Hall

Chairpersons: Masaru Ishii (Department of Immunology and Cell Biology, Graduate School of Medicine, Osaka University)
Hiroshi Takayanagi (Graduate School of Medicine, The University of Tokyo)

Overview of immune regulation by non-immune cells
Noriko Komatsu Department of Immunology Graduate School of Medicine and Faculty of Medicine, The University of Tokyo
8:30 ~ 9:00, Wednesday, December 7
OD OT03 Overview Talk 03

Room C: Conference Room A1

Chairpersons: Yuki Kagoya (Aichi Cancer Center Research Institute)
Seiichi Ohta (The University of Tokyo)

Current status and issues of synthetic biological approaches in cancer immunotherapy
Hiroshi Kawamoto Laboratory of Immunology, Institute for Life and Medical Sciences, Kyoto University, Kyoto, Japan / Laboratory ofRegenerative Immunology, International Center for Cell and Gene Therapy, Fujita Health University, Toyoake, Aichi, Japan

8:30 ~ 9:00, Wednesday, December 7
OD OT04 Overview Talk 04

Room D: Conference Room A2

Chairpersons: Satoko Arai (Graduate School of Medicine, The University of Tokyo)
Yohei Mikami (Keio University School of Medicine)

Resolution of inflammation: D'où venons-nous ? Que sommes-nous ? Où allons-nous ?
Yohei Mikami Division of Gastroenterology and Hepatology Department of Internal Medicine, Keio University School of Medicine
8:30 ~ 8:50, Wednesday, December 7
OD OT05 Overview Talk 05

Room E: Conference Room A3

Chairpersons: Shohei Hori (Graduate School of Pharmaceutical Sciences, The University of Tokyo)
Hideyuki Yoshida (RIKEN)

Overview talk: Immune tolerance and regulation
Hideyuki Yoshida RIKEN Center for Integrative Medical Sciences29

8:30 ~ 9:00, Wednesday, December 7
OD OT06 Overview Talk 06

Room F: Conference Room A4

Chairpersons: Motoi Yamashita (Department of Pediatrics and Developmental Biology, Graduate School of
Medical and Dental Sciences, Tokyo Medical and Dental University)
Yoshitaka Honda (Kyoto University)

Understanding immune system through human immune-mediated disorders
Motoi Yamashita Laboratory for Transcriptional Regulation, Center for Integrative Medical Sciences, RIKEN, Kanagawa, Japan
8:30 ~ 9:00, Thursday, December 8
OD OT07 Overview Talk 07

Room B: Civic Hall

Chairpersons: Masato Kubo (Tokyo University of Science/RIKEN Center for Integrative Medical Sciences (IMS), RIKEN Yokohama Institute)
Laura Mackay (University of Melbourne)

Understanding the mechanism of immunological memory
Masato Kubo Research Institute for Biomedical Science, Tokyo University of Science
8:30 ~ 9:00, Thursday, December 8
OD OT08 Overview Talk 08

Room C: Conference Room A1

Chairpersons: Masaru Ishii (Osaka University Graduate School of Medicine)
Takashi Shichita (Tokyo Metropolitan Institute of Medical Science)

Neuro-immune interaction in brain bioregulation
Takashi Shichita Stroke Renaissance Project, Tokyo Metropolitan Institute of Medical Science, Tokyo, Japan
8:30 ~ 9:00, Thursday, December 8
OD OT09 Overview Talk 09

Room D: Conference Room A2

Chairpersons: Satoko Tahara-Hanaoka (University of Tsukuba)
Hideaki Morita (National Research Institute for Child Health and Development)

Gateway to allergic reactions
Satoko Tahara-Hanaoka Department of Immunology, Faculty of Medicine, Life Science Center for Survival Dynamics, Tsukuba Advanced
Research Alliance (TARA), R&D Center for Innovative Drug Discovery, University of Tsukuba, Tsukuba-city, Japan

8:30 ~ 9:00, Thursday, December 8
OD OT10 Overview Talk 10

Room E: Conference Room A3

Chairpersons: Hideki Hara (Asahikawa Medical University)
Akinori Takaoka (Hokkaido University)

Advances in research of innate immune sensors and diseases
Hideki Hara Department of Microbiology and Immunochemistry, Asahikawa Medical University, Asahikawa, Japan / Department ofMicrobiology and Immunology, Keio University School of Medicine, Tokyo, Japan30

8:30 ~ 9:00, Thursday, December 8
OD OT11 Overview Talk 11

Room F: Conference Room A4

Chairpersons: Shinobu Suzuki (Medical Science and Business Liaison Organization, Kyoto University)
Shih-Yu Chen (Academia sinica)

Single-cell technologies for System Immunology in a New Era
Shinobu Suzuki Kyoto University, Graduate School of Medicine, Medical Science and Business Liaison Organization
8:30 ~ 9:00, Friday, December 9

OT12 Overview Talk 12

Room B: Civic Hall

Chairpersons: Yoko Hamazaki (Center for iPS cell Research and Application, Kyoto University)
Kenji Chamoto (Center for Cancer Immunotherapy and Immunobiology, Kyoto University Graduate School)

Immunity among Aging Populations – A New Research Area Emerging from the COVID-19
Pandemic
Yoko Hamazaki Laboratory of Immunobiology, Graduate school of Medicine, Kyoto University, Kyoto, Japan / Center for iPS Cell Research andApplication (CiRA), Kyoto University, Kyoto, Japan

8:30 ~ 9:00, Friday, December 9
OD OT13 Overview Talk 13

Room C: Conference Room A1

Chairpersons: Toshiaki Ohteki (Medical Research Institute, Tokyo Medical and Dental University)
Masaki Miyazaki (Kyoto University)

Recent concepts and advances in developmental branching and inteplay between innate andadaptive immunity
Ryo Morimoto Max Planck Institute of Immunobiology and Epigenetics, Freiburg, Germany
8:30 ~ 9:00, Friday, December 9
OD OT14 Overview Talk 14

Room D: Conference Room A2

Chairpersons: Kenji Kabashima (Department of Dermatology, Kyoto University Graduate School of Medicine)
Atsushi Kumanogoh (Osaka University)

Advances of cytokine-targeted therapies in inflammatory skin diseases
Tetsuya Honda Department of Dermatology, Hamamatsu University School of Medicine
8:30 ~ 9:00, Friday, December 9

OT15 Overview Talk 15

Room E: Conference Room A3

Chairpersons: Yumiko Oishi (Nippon Medical School)
Yusuke Endo (Laboratory of Medical Omics Research, KAZUSA DNA RESEARCH INSTITUTE)

Recent advances in immunometabolism research
Masakatsu Yamashita Department of Immunology, Graduate School of Medicine, Ehime University, Ehime, Japan31

8:30 ~ 9:00, Friday, December 9

OT16 Overview Talk 16

Room F: Conference Room A4

Chairpersons: Kenya Honda (Keio University School of Medicine)
Kiyoshi Takeda (Graduate School of Medicine, Osaka University)

Toward the development of defined microbial therapeutics
Kenya Honda Department of Microbiology and Immunology, Keio University School of Medicine, Tokyo, JAPAN / RIKEN Center for Integrative
Medical Sciences (IMS) , Yokohama, Japan32

SymposiumProgram for Symposia
Symposium 01

Room A 9:00 ~ 11:50 December 7

S01. Immune response against SARS-CoV-2 will be discussed.
Sponsored by International Immunology
Chairpersons: Hisashi Arase (WPI Immunology Frontier Research Center, Osaka University)
Saya Moriyama (National Institute of Infectious Diseases)
OD

OD

OD

S01-01

Adaptive responses in infection and vaccination to SARS CoV2 and its variants

9:00~9:30

Alessandro Sette La Jolla Institute for Immunology

S01-02T cell responses against SARS-CoV-2

9:30~10:00

Sho Yamasaki RIMD, IFReC, Osaka University

S01-03Host-pathogen interaction in SARS-CoV-2 infection

10:00~10:30

Hisashi Arase Laboratory of Immunochemistry, WPI Immunology Frontier Research Center, Osaka University / Department of
Immunochemistry, Research Institute for Microbial Diseases, Osaka University

OD

OD

S01-04

Broadly neutralizing antibody against SARS-CoV-2 variants

10:30~11:00

Saya Moriyama Research Center for Drug and Vaccine Development, National Institute of Infectious Diseases, Tokyo, Japan

S01-05

Tackling viral infections by human monoclonal antibodies

11:00~11:30

Davide Corti Humabs BioMed SA, A Subsidiary Of Vir Biotechnology, Bellinzona, Switzerland

S01-06

Multisystem Inflammatory Syndrome in Children (MIS-C) and Long-COVID: the SARS-CoV-2
Viral Superantigen Hypothesis and autoimmunity

11:30~11:50

Moshe Arditi Cedars-Sinai Medical Center, Department of Pediatric Infectious Diseases and Immunology, Infectious and Immunological
Diseases Research Center, Los Angeles, CA

Symposium 02

Room B 9:00 ~ 11:30 December 7

S02. Non-immune cell immunology : JCR-JSI Joint Session
Chairpersons: Masaru Ishii (Department of Immunology and Cell Biology, Graduate School of Medicine, Osaka University)
Hiroshi Takayanagi (Graduate School of Medicine, The University of Tokyo)
OD

OD

OD

OD

S02-01Landscape of immunological responses to Janus kinase inhibitors in synovial fibroblasts

9:00~9:30

Haruka Tsuchiya Department of Allergy and Rheumatology, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan

S02-02

Targeting fibroblasts in inflammatory arthritis

9:30~10:00

Adam Croft University of Birmingham, United Kingdom

S02-03

Gut pTreg development governed by “microbiota-gut-liver-brain-gut axis“

10:00~10:30

Takanori Kanai Division of Gastroenterology and Hepatology, Department of Internal Medicin,Tokyo,Japan

S02-04

Diversity of thymic stromal cells for T cell repertoire selection

10:30~11:00

Takeshi Nitta Department of Immunology, Graduate School of Medicine, The University of Tokyo
35

OD

S02-05

Cellular niches for hematopoietic stem and progenitor cells in the adult bone marrow

11:00~11:30

Yoshiki Omatsu Laboratory of Stem Cell Biology and Developmental Immunology, Graduate School of Frontier Biosciences, Osaka University

Symposium 03

Room C 9:00 ~ 11:30 December 7

S03. Perspectives of synthetic biology for cancer immunology
Chairpersons: Yuki Kagoya (Aichi Cancer Center Research Institute)
Seiichi Ohta (The University of Tokyo)
OD

OD

S03-01

VHH antibody as a drug modality: synthetic biologics

9:00~9:30

Kohei Tsumoto School of Engieering, The University of Tokyo

S03-02Controlling physicochemical property of synthetic nanoparticles and its application for thedetection of immune-related biomarkers

9:30~10:00

Seiichi Ohta Institute of Engineering Innovation, School of Engineering, The University of Tokyo, Tokyo, Japan / Department of Bioengineering,
School of Engineering, The University of Tokyo, Tokyo, Japan / Department of Chemical System Engineering, School ofEngineering, The University of Tokyo, Tokyo, Japan / JST PRESTO, Tokyo, Japan

OD

OD

S03-03New cancer therapy using photo chemical reaction

10:00~10:30

Mikako Ogawa Faculty of Pharmaceutical Sciences, Hokkaido University, Sapporo, Japan

S03-04

Synthetic immunology to enhance safety and efficacy in adoptive cancer immunotherapy

10:30~11:00

Yuki Kagoya Division of Immune Response, Aichi Cancer Center Research Institute, Nagoya, Japan / Division of Cellular Oncology,
Department of Cancer Diagnostics and Therapeutics, Nagoya University Graduate School of Medicine, Nagoya, Japan

S03-05Synthetic biology approaches in cancer immunology and immunotherapy

11:00~11:30

Naoto Hirano Tumor Immunotherapy Program, Princess Margaret Cancer Centre, Toronto, ON, Canada

Symposium 04

Room D 9:00 ~ 11:30 December 7

S04. Introduction to Innovative Science for "Resolution of
Inflammation" : SFI-JSI Joint Session
Chairpersons: Satoko Arai (Graduate School of Medicine, The University of Tokyo)
Yohei Mikami (Keio University School of Medicine)
OD

OD

S04-01

Delineation, birth, and self-organization of the intestinal stem cell niche

9:00~9:35

Ramesh Shivdasani Dana-Farber Cancer Institute and Harvard Medical School, Boston, United States

S04-02

Regulation of hypothalamic functions by mirobiota and inflammation

9:35~10:10

Gerard Eberl Institut Pasteur, Paris, France

S04-03

Pathological inflammatory memories - Immune-neuro interaction shapes the transformationof inflamed tissue -10:10~10:35

Kiyoshi Hirahara Department of Immunology, Graduate School of Medicine, Chiba University

OD

S04-04Cell death-induced chronic inflammation and metabolic changes in macrophage

10:35~11:00

Miyako Tanaka Department of Molecular Medicine and Metabolism, Research Institute of Environmental Medicine, Nagoya University, Nagoya

36

S04-05
11:00~11:25

A role of the phagocytic removal system in resolution of inflammation and its therapeutic
implication
Satoko Arai Graduate School of Medicine, The University of Tokyo, Tokyo, Japan / The Institute for AIM Medicine, Tokyo, Japan

Symposium 05

Room E 8:50 ~ 11:30 December 7

S05. Immune tolerance and regulation: toward a comprehensive
understanding of immune and tissue homeostasis : DGFI-JSI
Joint Session
Chairpersons: Shohei Hori (Graduate School of Pharmaceutical Sciences, The University of Tokyo)
Hideyuki Yoshida (RIKEN)
OD

OD

OD

S05-01

mTECs, peripheral tissue-specific antigens, and beyond

8:50~9:20

Hideyuki Yoshida RIKEN Center for Integrative Medical Sciences

S05-02Autoimmune pathology caused by the abnormal function of thymic epithelial cells

9:20~9:50

Mitsuru Matsumoto Institute for Enzyme Research, Tokushima University

S05-03

I-Ag7 β56/57 polymorphisms regulate non-cognate negative selection to CD4 T cellorchestrators of type-1 diabetes

9:50~10:25

Eric Huseby University of Massachusetts Medical School, Worcester, MA USA

S05-04

Molecular control of Treg cell differentiation and function by Foxp3 and TCR signals

10:25~10:55

Shohei Hori Graduate School of Pharmaceutical Sciences, The University of Tokyo

S05-05

Nonlymphoid-tissue Treg cells in man and mouse

10:55~11:30

Markus Feuerer Leibniz Institute for Immunotherapy, Division of Immunology, Regensburg, Germany / Chair for Immunology, University ofRegensburg, Regensburg, Germany

Symposium 06

Room F 9:00 ~ 11:30 December 7

S06. From Pathology to Physiology: Understanding immune systemthrough human immune-mediated disorders
Chairpersons: Motoi Yamashita (Department of Pediatrics and Developmental Biology, Graduate Schoolof Medical and Dental Sciences, Tokyo Medical and Dental University)
Yoshitaka Honda (Kyoto University)
OD

S06-01

Inborn errors of cell death - a novel concept in human autoinflammatory diseases

9:00~9:30

Hirotsugu Oda CECAD, University of Cologne, Cologne, Germany

S06-02Model mice of human inborn errors of immunity showing mixed manifestations ofautoinflammation, immunodeficiency and/or autoimmunity

9:30~10:00

Tsuneyasu Kaisho Department of Immunology, Institute of Advanced Medicine, Wakayama Medical University, Wakayama, Japan

37

OD

S06-03
10:00~10:30

Unwinding the molecular pathogenesis of a novel inherited immunodysregulatory disordercaused by loss-of-function mutations in DExD/H box helicase SBNO2
Kazuyuki Meguro Laboratory of Clinical Immunology and Microbiology, Division of Intramural Research, National Institute of Allergy and
Infectious Diseases, National Institutes of Health, Bethesda, USA. / Department of Allergy and Clinical Immunology,
Graduate School of Medicine, Chiba University, Chiba, Japan.

OD

S06-04IKAROS and AIOLOS deficiency in PID

10:30~11:00

Hye Sun Kuehn Immunology Service, Department of Laboratory Medicine, NIH Clinical Center, Bethesda, MD, USA.

S06-05Interference of Bcl11a-Bcl11b heterodimer function by BCL11B N441K mutant during
neurogenesis and thymopoiesis

11:00~11:30

Kazuki Okuyama Laboratory for Transcriptional Regulation, IMS, RIKEN Yokohama

Symposium 07

Room B 9:00 ~ 11:30 December 8

S07. Recent advances in immunological memory : ASI-JSI Joint
Session
Chairpersons: Masato Kubo (Tokyo University of Science/RIKEN Center for Integrative
Medical Sciences (IMS), RIKEN Yokohama Institute)
Laura Mackay (University of Melbourne)
OD

OD

S07-01Germinal center B cell selection and survival regulated by optimal BCR signaling

9:00~9:30

Takeshi Inoue Immunology Frontier Research Center, Osaka University, Osaka, Japan

S07-02

SARS-CoV-2 booster vaccination rescues attenuated IgG1 memory B cell response inpatients with primary antibody deficiency syndromes

9:30~10:00

Brian Laidlaw Washington University in St. Louis, St. Louis, MO United States of America

OD

S07-03
10:00~10:30

Generation and maintenance of epithelial-tropic CD8+ T cells in the peripheral tissues andtumor
Shiki Takamura Department of Immunology, Kindai University Faculty of Medicine, Osaka, Japan

OD

OD

S07-04

Runx3 drives a tissue-residency program that is absent in CD4+ T cells

10:30~11:00

Laura Mackay The Peter Doherty Institute for Infection and Immunity, The University of Melbourne

S07-05Development and Maintenance of Tissue resident memory T cells

11:00~11:30

Donna Farber Columbia University, New York, NY USA

Symposium 08

Room C 9:00 ~ 11:30 December 8

S08. Neuro-immune and inflammatory interaction : DGFI-JSI Joint
Session
Chairpersons: Masaru Ishii (Osaka University Graduate School of Medicine)
Takashi Shichita (Tokyo Metropolitan Institute of Medical Science)
OD

S08-01

Lipid metabolism triggering neural repair in brain ischemia

9:00~9:26

Takashi Shichita Stroke Renaissance Project, Tokyo Metropolitan Institute of Medical Science, Tokyo, Japan

38

OD

S08-02
9:26~10:02

Stroke induces a cerebral tissue-resident T cell population which modulates long-term
outcome
Arthur Liesz Institute for Stroke and Dementia Research, LMU University, Munich, Germany

OD

S08-03

Identification of a neuron-associated macrophage in the liver

10:02~10:28

Masaru Ishii Department of Immunology and Cell Biology, Graduate School of Medicine, Osaka University

S08-04

Specification of CNS macrophage subsets occurs postnatally in defined niches

10:28~11:04

Marco Prinz Institute of Neuropathology, Faculty of Medicine, University of Freiburg, Freiburg, Germany / Center for Basics in
NeuroModulation (NeuroModulBasics), Faculty of Medicine, University of Freiburg, Freiburg, Germany / Signalling ResearchCentres BIOSS and CIBSS, University of Freiburg, Freiburg, Germany

OD

S08-05

Physiological and pathological functions of microglia

11:04~11:30

Hiroaki Wake Department of Anatomy and Molecular Cell Biology Nagoya University Graduate School of Medicine

Symposium 09

Room D 9:00 ~ 11:30 December 8

S09. Recent Advances in Allergic Research : JSI-JSA Joint Session
Chairpersons: Satoko Tahara-Hanaoka (University of Tsukuba)
Hideaki Morita (National Research Institute for Child Health and Development)
OD

S09-01The Importance of Epithalial Barriers in Allergic and Autoimmune Diseases

9:00~9:30

Cezmi Akdis Swiss Institute of Allergy and Asthma Research, Davos, Switzerland

S09-02

Environmental factors trigger allergic inflammation through disruption/activation ofepithelial cells

9:30~10:00

Hideaki Morita Department of Allergy and Clinical Immunology, National Research Institute for Child Health and Development, Tokyo, Japan

OD

S09-03

Clec10a regulates mite-induced dermatitis

10:00~10:30

Kazumasa Kanemaru Department of Immunology, Faculty of Medicine, University of Tsukuba / Cellular Genetics Programme, Wellcome
Sanger Institute

OD

S09-04Homeostatic mechanisms of stratum corneum as niche for skin microbiota

10:30~11:00

Masayuki Amagai Department of Dermatology, Keio University School of Medicine / Laboratory for Skin Homeostasis, RIKEN Center for
Integrative Medical Sciences

OD

S09-05
11:00~11:30

Innate IL-13 is a skin ‘niche factor’ necessary for dermal dendritic cell differentiation andfunctionFranca Ronchese Malaghan Institute of Medical Research, Wellington, New Zealand39Symposium 10

Room E 9:00 ~ 11:30 December 8

S10. Advances in research of innate immune sensor and diseases :US-Japan Immunology Program Co-organized Session
Chairpersons: Hideki Hara (Asahikawa Medical University)
Akinori Takaoka (Hokkaido University)
OD

S10-01

Inflammasome-mediated exacerbation of infectious diseases and its application

9:00~9:30

Hideki Hara Department of Microbiology and Immunochemistry, Asahikawa Medical University, Asahikawa, Japan / Department ofMicrobiology and Immunology, Keio University School of Medicine, Tokyo, Japan

OD

OD

OD

OD

S10-02

Decoding Cell Death

9:30~10:00

Carla Rothlin Yale University, New Haven, CT, USA

S10-03Novel sensing mechanism of a damage signature for antiviral defense

10:00~10:30

Akinori Takaoka Division of Signaling in Cancer and Immunology, Institute for Genetic Medicine, Hokkaido University, Sapporo, Japan

S10-04

Tau activates microglia via the PQBP1-cGAS-STING pathway to promote brain inflammation

10:30~11:00

Hitoshi Okazawa Department of Neuropathology, Tokyo Medical and Dental University

S10-05

Understanding Microbiota-Host Innate Immunity Interactions in Crohn’s Disease

11:00~11:30

Gabriel Nunez University of Michigan Medical School, Ann Arbor, Michigan, USA

Symposium 11

Room F 9:00 ~ 11:30 December 8

S11. Single-cell technologies for System Immunology in a New Era
Chairpersons: Shinobu Suzuki (Medical Science and Business Liaison Organization, Kyoto University)
Shih-Yu Chen (Academia sinica)
OD

S11-01
9:05~9:33

Prioritized single-cell proteomics reveals molecular and functional polarization acrossprimary macrophages
Nikolai Slavov Departments of Bioengineering, Northeastern University, Cambridge, Boston, USA

OD

S11-02Single cell RNA sequencing of antigen-presenting cells in inflammatory skin diseases

9:33~10:01

Satoshi Nakamizo Department Dermatology, Kyoto University Graduate School of Medicine

S11-03Single Cell Systems-Structured View of Immune Responses

10:01~10:29

Shih-Yu Chen Institute of Biomedical Sciences, Academia Sinica, Taipei, Taiwan

S11-04

Deciphering pathogen-specific T cell responses to a clonotype resolution

10:29~10:57

Xiuyuan Lu Laboratory of Molecular Immunology, Immunology Frontier Research Center, Osaka University, Suita, Japan

S11-05Single-cell Sequencing of the B Cell Transcriptome and Repertoire Reveals Divergent
Vaccine Responses to SARS-CoV-2 S1 and S2

10:57~11:25

Tobias V. Lanz Stanford University, Division of Rheumatology and Immunology, Stanford, CA, USA40

Symposium 12

Room B 9:00 ~ 11:30 December 9

S12. The impact of aging and senescence on Immunity : US-Japan
Immunology Program Co-organized Session
Chairpersons: Yoko Hamazaki (Center for iPS cell Research and Application, Kyoto University)
Kenji Chamoto (Center for Cancer Immunotherapy and Immunobiology, Kyoto University Graduate School)
OD

S12-01
9:00~9:30

Spermidine improves defective anti-tumor immunity in aged mice by direct activation of
fatty acid oxidation in CD8+ T cells
Kenji Chamoto Division of Immunology and Genomic Medicine, Center for Cancer Immunotherapy and Immunobiology, Kyoto University
Graduate School of Medicine, Kyoto, Japan

S12-02
9:30~10:00

Escape from senescence surveillance by PD-L1-PD1 immune checkpoint and its blockade
ameliorates various senescence-associated disorders
Makoto Nakanishi Division of Cancer Cell Biology, Institute of Medical Science, University of Tokyo

OD

S12-03

Immune aging in mice and humans

10:00~10:30

Maxim Artyomov Washington University School of Medicine (St Louis)

S12-04Age-related and individual heterogeneity of immune responses to SARS-CoV-2 mRNA
vaccine10:30~11:00

Yoko Hamazaki Center for iPS Cell Research and Application (CiRA), Kyoto University, Kyoto, Japan / Laboratory of Immunobiology,
Graduate school of Medicine, Kyoto University, Kyoto, Japan

S12-05

Immune Surveillance of Senescent Cells

11:00~11:30

Scott Lowe Howard Hughes Medical Institute / Cancer Biology & Genetics Program, Sloan Kettering Institute, Memorial Sloan Kettering
Cancer Center, New York, NY USA

Symposium 13

Room C 9:00 ~ 11:30 December 9

S13. Developmental branching and interplay between innate andadaptive immunity : DGFI-JSI Joint Session
Chairpersons: Toshiaki Ohteki (Medical Research Institute, Tokyo Medical and Dental University)
Masaki Miyazaki (Kyoto University)
OD

OD

S13-01

Emergence of adaptive lymphoid lineages in vertebrates

9:00~9:30

Ryo Morimoto Max Planck Institute of Immunobiology and Epigenetics, Freiburg, Germany

S13-02To B (T), or not to B (T). That is the question. What drives the lineage choice of the adaptive
or innate immune cells?

9:30~10:00

Masaki Miyazaki Institute for Life and Medical Sciences, Dept. Immunology

OD

S13-03

Deconvolution of hematopoiesis by Polylox barcoding

10:00~10:30

Hans-Reimer Rodewald Department for Cellular Immunology, German Cancer Research Center, Heidelberg, Germany

S13-04

Immune Privileged Stem Cells, Niche, and Tregs—New "Stem-Immunology" forTransplantation, Injury, and Cancer

10:30~11:00

Joji Fujisaki Center for Inflammation Research, Division of Clinical Immunology, Beth Israel Deaconess Medical Center, Harvard Medical
School / Columbia Center for Translational Immunology, Columbia University College of Physicians and Surgeons

41

OD

S13-05

B cell: an amplifier of myeloid cell production triggered by infection

11:00~11:30

Masashi Kanayama

Department of Biodefense Research, Medical Research Institute, Tokyo Medical and Dental University (TMDU), Tokyo, Japan

Symposium 14

Room D 9:00 ~ 11:30 December 9

S14. Recent advances in clinical application of cytokine/JAK research :KAI-JSI Joint Session
Chairpersons: Kenji Kabashima (Department of Dermatology, Kyoto University Graduate School of Medicine)
Atsushi Kumanogoh (Osaka University)
OD

S14-01

Cytokine signaling: Bench to bedside and back.

9:00~9:30

John O'shea National Institute of Health

S14-02

Sensory neuronal STAT3 is critical for IL-31 receptor expression and inflammatory itch

9:30~10:00

Takaharu Okada RIKEN Center for Integrative Medical Sciences, Yokohama, Japan

S14-03

Targeting Angio-lymphokine for Autoimmune Diseases

10:00~10:30

Wan-Uk Kim Center for Integrative Rheumatoid Transcriptomics and Dynamics, The Catholic University of Korea, Seoul, Korea / Department
of Internal Medicine, The Catholic University of Korea, Seoul, Korea

OD

S14-0410:30~11:00

Severe COVID-19 immunopathology is mediated by type I IFNs and driven by activation ofcGAS-STING
Michel Gilliet Department of Dermatology, Lausanne University Hospital, Switzerland

S14-05

Recent advances in epithelial cytokine-targeted therapy in asthma

11:00~11:30

Hiroshi Nakajima Department of Allergy and Clinical Immunology, Graduate School of Medicine, Chiba University, Chiba, Japan

Symposium 15

Room E 9:00 ~ 11:30 December 9

S15. Recent Advances in immunometabolism
Chairpersons: Yumiko Oishi (Nippon Medical School)
Yusuke Endo (Laboratory of Medical Omics Research, KAZUSA DNA RESEARCH INSTITUTE)

OD

S15-01

T cell metabolic repertoire - a complex endpoint

9:00~9:30

Christoph Hess University of Cambridge, Cambridge, UK / University of Basel, Basel, Switzerland

S15-02

Regulation of brain lipid metabolism after ischemic stroke by brain immune cells

9:30~10:00

Minako Ito Medical Institute of Bioregulation, Kyushu University, Fukuoka, Japan

S15-03Krebs Cycle reborn in macrophages

10:00~10:30

Luke O'Neill School of Biochemistry and Immunology

S15-04

Regulation of social behavior by ILC3s

10:30~11:00

Michio Miyajima Keio University School of Medicine, Tokyo, Japan / RIKEN Center for Integrative Medical Sciences (IMS), Yokohama,
Kanagawa, Japan

OD

S15-05

A novel mode of autophagy terminates STING signalling

11:00~11:30

Tomohiko Taguchi Tohoku University
42Symposium 16

Room F 9:00 ~ 11:30 December 9

S16. Microbiota and the host immune system : US-Japan
Immunology Program Co-organized Session
Chairpersons: Kenya Honda (Keio University School of Medicine)
Kiyoshi Takeda (Graduate School of Medicine, Osaka University)

S16-01

Cellular senescence and cancer : a gut microbial connection

9:00~9:30

Eiji Hara Research Institute for Microbial Diseases, Osaka University, Suita JP

S16-02

TCR-Vγδ usage distinguishes pro- and anti-tumor intestinal γδ T cell subsets

9:30~10:00

Mucida Daniel Laboratory of Mucosal Immunology, The Rockefeller University, New York, NY, USA. / Department of Medicine, Divisionof Digestive and Liver Diseases, Columbia University, New York, NY, USA. / Department of Medicine and Department of
Biomedical Sciences, Cedars-Sinai Cancer Institute, Cedars-Sinai Medical Center, Los Angeles, CA, USA. / Howard Hughes
Medical Institute, The Rockefeller University, New York, NY, USA.

OD

S16-03
10:00~10:30

Identification of bacterial metabolites that exacerbate intestinal inflammation in Crohn’sdisease patients
Kiyoshi Takeda Osaka University Graduate School of Medicine / Immunology Frontier Research Center, Osaka University

OD

OD

S16-04

SARS-CoV-2 and vaccine-induced immunity

10:30~11:00

Carolina Lucas Department of Immunobiology, Yale University School of Medicine, New Haven, CT, USA

S16-05

Impact of gut microbial metabolites short-chain fatty acids on the host immunity andphysiology

11:00~11:30

Hiroshi Ohno Laboratory for Intestinal Ecosystem, RIKEN Center for Integrative Medical Sciences, Yokohama, Japan43

Workshop○ : Presenter

OralDecember 7
WS01

T cell development (thymus and homeostasis)

15:30 ~ 16:45 Room A
Chairpersons: Ichiro Taniuchi, Eri Ishikawa

Despite of a long history of the primary T cell development in the thymus, important questions remain elusive in this researcharea. For instance, precise molecular mechanism for “positive and negative selection based on self vs non-self recognition isstill unraveled. On the contrary, new questions arose in the filed such as how age-related or environmental changes affect T
cell development. The “T cell development” session is organized to share and discuss results of current studies with aiming
to advance our understanding of the regulatory mechanisms of primary T cell development in a steady-state. The topics
in the session include selection processes, T cell repertoire formation, mechanisms to establish central tolerance, roles ofthymic epithelium cells and dendritic cells, cellular signaling from TCR, transcriptional and epigenetic regulation as well as
development of new technology and materials.

WS01-01-O/P

Notch signaling triggers T-lineage program via Tcf7-dependnent and -independent mechanisms〇 Ken-Ichi Hirano, Katsuto Hozumi, Hiroyuki Hosokawa
Department of Immunology, Tokai University School of Medicine, Kanagawa, Japan

WS01-02-O/P

Phosphorylation of Runx proteins controls thymocyte fate
〇 Chihiro Ogawa, Kazuki Okuyama, Satoshi Kojo, Sawako Muroi, Ichiro Taniuchi
Riken, Center for Integrative Medical Sciences, Laboratory for Transcriptional Regulation, Yokohama, Japan

WS01-03-O/P

THEMIS acts in the cytoplasm and nucleus to regulate T cell differentiation〇 Kiyokazu Kakugawa, Hilde Cheroutre
Laboratry for ImmuneCrosstalk, RIKEN Center for Integrative Medical Science

WS01-04-O/P

Induction of central tolerance by arginine methylation〇 Ryunosuke Muro, Takeshi Nitta, Hiroshi Takayanagi
Department of Immunology, Graduate School of Medicine and Faculty of Medicine, The University of Tokyo

WS01-05-O/P

Isolation of thymic self-reactive T cells with differentiation preference for regulatory T cells
1, 2)
1, 2)
〇 Ryoji Kawakami , Shimon Sakaguchi
1)Institute for Life and Medical Sciences, Kyoto University, Kyoto, Japan, 2)Immunology Frontier Research Center, Osaka University, Osaka, Japan

WS01-06-O/P

Excess proliferation and activation of self-reactive memory-phenotype CD4+ T lymphocytes are tonicallyinhibited by regulatory T cells in steady state〇 Jing Li, Ziying Yang, Akihisa Kawajiri, Kosuke Sato, Shunichi Tayama, Yuko Okuyama, Naoto Ishii, Takeshi Kawabe
Department of Microbiology and Immunology, Tohoku University Graduate School of Medicine, Sendai, Japan.

WS01-07-O/P

Long-term caloric restriction ameliorates T cell immunosenescence in mice
〇 Sachi Tanaka, Katsunori Endo
Shinshu University, Nagano, Japan

47

WS02

Anti-tumor Effectors, Ag presentation

15:30 ~ 16:45 Room B
Chairpersons: Keiko Udaka, Toshihiko Torigoe

This session focuses on effector cells in anti-tumor responses, antigen presentation by MHC molecules, and immune responses
in the tumor microenvironment. Despite proinflammatory tissue destructions and the presence of tumor antigens, immune
responses in the tumors tend to be attenuated by the suppressive local environment. Effector cells such as CD8 and CD4 T
cells, γδT cells, and NKT eliminate tumor cells and contribute substantially to shaping the local immune responses. Various
innate lymphoid cells, DCs, macrophages, epithelial cells, and tumor cells also affect the outcome. We would like to discuss the
dynamic nature of the tumor microenvironment. The latest development in immunization methods will also be presented.

WS02-02-O/P

T-Cell Rejuvenation: a novel approach to partially reprogram T cells to improve their immunotherapeutic
properties〇 Raul Vizcardo, Yasuhiro Yamazaki, Takuya Maeda, Yin Huang, Naritaka Tamaoki, Burak Kutlu, Jessica Fioravanti,
Shobha Potluri, Nicholas P. Restifo
Lyell Immunopharma Inc, South San Francisco, CA, USA

WS02-03-O/P

scRNAseq analysis revealed that activation of progenitor-like Tex population in tumor elicited a strong
effector function in the later population in Socs3 cKO mice
〇 Setsuko Mise-Omata, Akihiko Yoshimura
Keio University School of Medicine, Department of Microbiology and Immunology, Tokyo, JAPAN

WS02-04-O/P

CD69 regulates anti-tumor CD8T cell responses〇 Ryo Nasu, Yangsong Wang , Yukihiro Endo , Ichita Hasegawa, Tatsuya Ueno, Yukiyoshi Mita,
Shinichiro Motohashi, Toshinori Nakayama, Motoko Y. Kimura
Graduate school of Medicine, Chiba University

WS02-06-O/P

Antitumor effect of anti-HLA-F antibody on colon cancer in patient-derived xenografts (PDX) model〇 Noriko Ouji-Sageshima, Masahiro Kitabatake, Ryutaro Furukawa, Toshihiro Ito
Department of Immunology, Nara Medical University, Nara, Japan

WS02-07-O/P

Consensus molecular subtypes specific roles of γδ T cells in colorectal cancer
1, 2)
1, 2)
1)
2)
3)
4)
〇 Toshiyasu Suzuki , Anna Kilbey , Rachel Ridgway , Hannah Hayman , Ryan Bryne , Michael Verzi ,
5)
3)
2)
6)
1, 2)
1, 2)
Simon Leedham , Philip Dunne , Joanne Edwards , Adrian Hayday , Owen Sansom , Seth Coffelt
1)

Cancer Research UK Beatson Institute, Glasgow, UK, 2)Institute of Cancer Sciences, University of Glasgow, Glasgow, UK, 3)School of Medicine,
Dentistry and Biomedical Sciences, Queen’s University, Belfast, UK, 4)Department of Genetics, Human Genetics Institute of New Jersey, Rutgers
Cancer Institute of New Jersey, Rutgers University, New Brunswick, New Jersey, USA , 5)Nuffield Department of Medicine, Oxford University,
Oxford, UK, 6)The Francis Crick Institute, London, UK
WS02-08-O/P

Alpha-galactosylceramide-loaded antigen-presenting cells induce direct cytotoxicity and adjuvant effects
of induced pluripotent stem cell-derived natural killer T cells
1, 2)
1)
1)
1)
1)
1)
〇 Takahiro Aoki , Genta Kitahara , Momoko Okoshi , Midori Kobayashi , Munechik Yamaguchi , Hiroko Okura ,
3)
3)
3)
3)
2)
Masami Kawamura , Tomonori Iyoda , Kanako Shimizu , Shin-Ichiro Fujii , Shinichiro Motohashi , Haruhiko Koseki1)
1)

Laboratory for Developmental Genetics, RIKEN Center for Integrative Medical Science, 2)Medical immunology, Graduate School of Medicine,
Chiba University, 3)Laboratory for Immunotherapy, RIKEN Center for Integrative Medical Science
WS02-20-O/P

Serine threonine kinase 24 (STK24) mediates immune evasion signals in tumors by inducing multiple
immunosuppressive molecules
1, 2)
1, 2)
2)
2, 3)
2)
〇 Aya Misawa , Shigeki Ohta , Ryotaro Imagawa , Yuki Katoh , Hidetoshi Sumimoto ,
4)
5)
5)
1, 2)
Naomi Goto-Matsumoto , Kenta Nakamura , Ryuhei Okuyama , Yutaka Kawakami
1)
Department of Immunology, School of Medicine, International University of Health and Welfare, Chiba, Japan, 2)Division of Cellular Signaling,
Institute for Advanced Medical Research, Keio University School of Medicine, Tokyo, Japan, 3)Division of Anatomical Science, Departmentof Functional Morphology, Nihon University School of Medicine, Tokyo, Japan, 4)Center for Basic Medical Research, School of Medicine,International University of Health and Welfare, Chiba, Japan, 5)Department of Dermatology, Shinshu University School of Medicine

48

WS02-27-O/P

Innate immune components critical to the effect of oncolytic virus therapy with HSV-1
1)

2)

3)

4)

4)

5)

〇 Shumpei Uchida , Tsukasa Seya , Shizuo Akira , Ryutaro Fukui , Kensuke Miyake , Tomoki Todo ,Norimitsu Kadowaki1)
1)

Division of Hematology, Faculty of Medicine, Kagawa Univ., Kagawa, Japan, 2)Nebuta Research Institute for Life Sciences, Aomori Univ.,
Aomori, Japan, 3)Immunology Frontier Research Center, Osaka Univ., Osaka, Japan, 4)Division of Infectious Genetics, Institute of Medical
Science, Univ. Tokyo, Tokyo, Japan, 5)Division of Innovative Cancer Therapy, Institute of Medical Science, Univ. Tokyo, Tokyo, Japan

WS03

Infection and Immunity I

15:30 ~ 16:45 Room C
Chairpersons: Masahiro Yamamoto, Sujin Kang

Immunity against infection of pathogens is important for host survival. Proinflammatory cytokines are produced in innate
immune cells. Some of the cytokines subsequently activate adaptive immune cells to mediate cellular and humoral responses.
Interferon-γ, which is produced by innate and adaptive immune cells such as innate lymphoid cells, natural killer cells, Th1
cells and CD8+ T cells further activates cell-autonomous immunity in pathogen-infected cells to eradicate the microbes. Thus,
innate, adaptive and cell-autonomous immunity consist of host defense system. In this session, we selected studies in terms ofhost defense mechanism, cell surface receptors, immune regulation, cytokine induction and etc in immunity against bacteria,
parasites and fungi in particular.

WS03-01-O/P

Porphyromnas gingivalis infection triggers enhancement of severity for EAE following inflammasome
activation in macrophages〇 Tokuju Okano, Toshihiko Suzuki
Graduate School of Medical and Dental Sciences Tokyo Medical and Dental University (TMDU)

WS03-02-O/P

The effects of malaria on bone marrow hematopoietic stem cell niches
1, 2)
1)
1)
2, 3)
1, 2)
〇 Michelle Sue Jann Lee , Julia Matsuo-Dapaah , Camila Del Rosario Zorrilla , Ken J. Ishii , Cevayir Coban
1)

Division of Malaria Immunology, Institute of Medical Science, The University of Tokyo, Japan, 2)International Vaccine Design Center (VDesC),
The Institute of Medical Science, The University of Tokyo, Japan, 3)Division of Vaccine Science, Institute of Medical Science, The University ofTokyo, Japan
WS03-03-O/P

IFN-γ induced GTPases・GBPchr5 play an important role for anti-Toxoplasma host defense
1)

1, 2, 3)

〇 Ayumi Kuratani , Masahiro Yamamoto1)
Department of Immunoparasitology, RIMD, Osaka University, 2)Laboratory of Immunoparasitology, IFReC, Osaka University, 3)CIDER, Osaka
University

WS03-04-O/P

LILRB3 and LILRA6 recognize bacteria in an allele-specific manner1)

1, 2, 3)〇 Gen Hasegawa , Kouyuki Hirayasu
Rikinari Hanayama1, 2, 3, 8), Yifan Li3), Hisashi Arase4, 5), Masaya Yamaguchi6), Shigetada Kawabata7),

1)

Department of Immunology, Graduate School of Medical Sciences, Kanazawa University, Ishikawa, Japan, 2)Advanced Preventive Medical
Sciences Research Center, Kanazawa University, Ishikawa, Japan, 3)Department of Immunology, Graduate School of Advanced Preventive
Medical Sciences, Kanazawa University, Ishikawa, Japan, 4)Department of Immunochemistry, Research Institute for Microbial Diseases, Osaka
University, Osaka, Japan, 5)Laboratory of Immunochemistry, Immunology Frontier Research Center, Osaka University, Osaka, Japan,
6)
Bioinformatics Unit, Graduate School of Dentistry, Osaka University, Osaka, Japan, 7)Department of Oral and Molecular Microbiology, Graduate
School of Dentistry, Osaka University, Osaka, Japan, 8)WPI Nano Life Science Institute (NanoLSI), Kanazawa University, Ishikawa, Japan
WS03-05-O/P

A novel role of GRIM-19 in cytokine production in macrophages upon mycobacterial infection
1, 2, 3)〇 Giichi Takaesu, Tomomi Kurane2), Masayuki Umemura1, 2, 3), Goro Matsuzaki1, 2, 3)

1)

Tropical Biosphere Research Center, University of the Ryukyus, 2)Department of Host Defense, Graduate School of Medicine, University of the
Ryukyus, 3)Advanced Medical Research Center, Faculty of Medicine, University of the Ryukyus

49

WS03-06-O/P

The intracellular pathogen Francisella tularensis escapes from adaptive immunity by metabolic
adaptation
1, 2, 3)

, Takashi Shimizu4), Emi Ito2), Francois Legoux5), Sho Yamasaki2, 6, 7, 8), Olivier Lantz5),〇 Kensuke Shibata
Masahisa Watarai4)
1)

Department of Microbiology and Immunology, Yamaguchi University Graduate School of Medicine, Ube, Japan, 2)Department of Molecular
Immunology, Research Institute for Microbial Diseases, Osaka University, Suita, Japan, 3)Department of Ophthalmology, Graduate School of
Medical Sciences, Kyushu University, 4)Joint Faculty of Veterinary Medicine, Laboratory of Veterinary Public Health, Yamaguchi University,
Ube, Japan, 5)INSERM U932, PSL University, Institut Curie, Paris, France; Laboratoire d'immunologie clinique, Institut Curie, Paris, France;
Centre d'investigation Clinique en Biothérapie, Institut Curie (CIC-BT1428), Paris, France, 6)Laboratory of Molecular Immunology, Immunology
Frontier Research Center, Osaka University, Suita, Japan, 7)Division of Molecular Design, Medical Institute of Bioregulation, Kyushu University,
Fukuoka, Japan, 8)Division of Molecular Immunology, Medical Mycology Research Center, Chiba University, Chiba , Japan
WS03-07-O/P

Immunological mechanism for reactivated cryptococcosis in persistently infected mice after treatment
with FTY720
1)
2)
2)
3)
2, 4)
4)
〇 Michiko Yoshida , Nana Nakahata , Takeshi Shinomiya , Hayato Sato , Ko Sato , Jun Kasamatsu ,
5)
5)
2)
2)
Hiromasa Tanno , Emi Kanno , Keiko Ishii , Kazuyoshi Kawakami
1)
Department of Pediatrics, Tohoku University Graduate School of Medicine, Sendai, Miyagi, Japan, 2)Department of Medical Microbiology,
Mycology and Immunology, Tohoku University Graduate School of Medicine, Sendai, Miyagi, Japan, 3)Department of Plastic and Reconstructive
Surgery, Tohoku University Graduate School of Medicine, Sendai, Miyagi, Japan, 4)Department of Intelligent Network for Infection Control,
Tohoku University Graduate School of Medicine, Sendai, Miyagi, Japan, 5)Department of Translational Science for Nursing, Tohoku University
Graduate School of Medicine, Sendai, Miyagi, Japan

WS03-08-O/P

Immune activating receptors specific for variant surface antigens of Plasmodium falciparum
1)

2)

2)

1)

3, 4, 5)

〇 Akihito Sakoguchi , Samuel Chamberlain , Matthew Higgins , Shiroh Iwanaga , Hisashi Arase1)

Department of Molecular Protozoology, Research Institute for Microbial Diseases, Osaka University, Osaka, Japan, 2)Department ofBiochemistry, University of Oxford, Oxford, UK, 3)Department of Immunochemistry, Research Institute for Microbial Diseases, Osaka University,
Osaka, Japan, 4)Laboratory of Immunochemistry, WPI Immunology Frontier Research Center, Osaka University, Osaka, Japan, 5)Center for
Infectious Disease Education and Research, Osaka University, Osaka, Japan
WS03-09-O/P

Dermanyssus gallinae suppressively modulate host immune responses during infestation
1, 2)
2, 3)
2)
4)
4)
4)
〇 Sotaro Fujisawa , Shiro Murata , Masayoshi Isezaki , Takumi Sato , Eiji Oishi , Akira Taneno ,Naoya Maekawa3), Tomohiro Okagawa3), Satoru Konnai2, 3), Kazuhiko Ohashi2, 3, 5)
1)

Department of Molecular Genetics, Graduate School of Medical Science, Kanazawa University, 2)Department of Disease Control, Faculty of
Veterinary Medicine, Hokkaido University, 3)Department of Advanced Pharmaceutics, Faculty of Veterinary Medicine, Hokkaido University,
4)
Vaxxinova Japan K.K., 5)International Affairs Office, Faculty of Veterinary Medicine, Hokkaido University

WS04


Dendritic cells and macrophages-1: Immune regulation and disease perspectives
15:30 ~ 16:45 Room D
Chairpersons: Nobuyuki Onai, Chigusa Oda

Dendritic cells (DCs) and macrophages are present in all tissues. They regulate immune responses, development, and tissue
homeostasis, participating in the initiation and progression of various diseases. They express surface receptors or sensors thatrecognize extrinsic stimuli, regulate inflammatory cytokine production, and display multiple functions, contributing to immune
responses, inflammation, and disease. In this session, we will discuss the activation of dendritic cell and macrophage lineages
and their role in immune regulation, homeostasis, and disease progression. We welcome active and constructive discussion toextend insight into the functions of DCs and macrophages.

WS04-01-O/P

Dendritic cells regulate peripheral T cell survival through the CD47-SIRPα signaling
1)
1, 2)
1)
1)
1, 2)
1)
〇 Yasuyuki Saito , Satomi Komori , Hiroki Yoshida , Risa Sugihara , Tomoko Takai , Takenori Kotani ,1)
1, 2)
Yoji Murata , Takashi Matozaki
1)
Division of Molecular and Cellular Signaling, Department of Biochemistry and Molecular Biology, Kobe University Graduate School of
Medicine, Kobe, Japan, 2)Division of Biosignal Regulation, Department of Biochemistry and Molecular Biology, Kobe University Graduate
School of Medicine, Kobe, Japan50

WS04-03-O/P

Characterization of tissue macrophages involved in the pathogenesis of type I interferonopathy
1)

1)

2)

〇 Taku Sato , Toshiaki Ohteki , Takeshi Namiki
1)

Department of Biodefense Research, Medical Research Institute, Tokyo Medical and Dental University (TMDU), Tokyo, Japan, 2)Department of
Dermatology, Graduate School of Medical and Dental Sciences, Tokyo Medical and Dental University (TMDU), Tokyo, Japan.
WS04-04-O/P

Palladium-induced association of inter-MHC class I is involved in development of metal allergy
1)

1)

2)

1)

〇 Koyu Ito , Masato Kosuge , Yuri Takeda , Kouetsu Ogasawara
1)

Department of Immunobiology, Institute of Development, Aging, and Cancer, Tohoku University, 2)Division of Oral and Maxillofacial Surgery,
Department of Disease Management Dentistry, Tohoku University Graduate School of DentistryWS04-06-O/P

Endosomal abnormalities in dendritic cells cause autoimmune liver diseases
1)

2)

1)

3)

4)

〇 Shin-Ichiroh Saitoh , Kenichi Harada , Yoshiko Mori-Saitoh , Ge-Hong Sun-Wada , Tamami Denda ,Yasunori Ota4), Hiroshi Sagara5), Yuji Watanabe5), Yoh Wada6), Kensuke Miyake1, 7)
1)Division of Infectious Genetics, Department of Microbiology and Immunology, The Institute of Medical Science, The University of Tokyo,
Japan, 2)Department of Human Pathology, Kanazawa University School of Medicine, Kanazawa, Japan., 3)Department of Biochemistry, Facultyof Pharmaceutical Sciences, Doshisha Women's College, Kohdo, Kyotanabe, Kyoto Japan., 4)Department of Pathology, Research Hospital,The
Institute of Medical Science, The University of Tokyo, Tokyo Japan., 5)Medical Proteomics Laboratory, The Institute of Medical Science, The
University of Tokyo, Tokyo Japan., 6)Division of Biological Science, Institute of Scientific and Industrial Research, Osaka University, Ibaraki,
Osaka, Japan., 7)Laboratory of Innate Immunity, The Institute of Medical Science, The University of Tokyo, Tokyo, Japan.

WS04-08-O/P

Exposure to Multi-Wall Carbon Nanotubes Promotes Fibrous Proliferation by Production of Matrix
Metalloproteiase-12 via NF-κB Activation in Chronic Peritonitis〇 Takaaki Tsunematsu, Rieko Arakaki, Mami Sato, Kunihiro Otsuka, Naozumi Ishimaru
Department of Oral Molecular Pathology, Tokushima University Graduate School of Biomedical Sciences

WS04-11-O/P

A study of the effect of high-fat diet intake on microglia functional activity in APPNL-G-F/NL-G-F
Alzheimer's disease model mice
〇 Shuhan Yang, Hirofumi Miyazaki, Yuji Owada
Department of Organ Anatomy, Graduate School of Medicine, Tohoku University, Sendai, Japan

WS04-13-O/P

Progesterone prevents murine miscarriage by suppressing the immunostimulatory activity of macrophage
1, 2)
1, 2)
1, 2)
1)
3)
2)
1)
〇 Yasuyuki Negishi , Hajime Ino , Yumi Horii , Eri Koike , Yoshio Shima , Shunji Suzuki , Rimpei Morita
1)
Department of Microbiology and Immunology, Nippon Medical School, Tokyo, Japan, 2)Department of Obstetrics and Gynecology, Nippon
Medical School, Tokyo, Japan, 3)Department of Pediatrics, Nippon Medical School Musashikosugi Hospital, Kanagawa, Japan

WS04-16-O/P

Intranasal administration of ceramide liposomes inhibits ragweed pollen-induced allergic rhinitis bytargeting CD300f
1)
1, 2)
1)
1)
1)
1, 3)
1, 4)
〇 Ayako Kaitani , Takuma Ide , Kumi Izawa , Tomoaki Ando , Akie Maehara , Lisa Yamamoto , Yasuharu Kume ,Hexing Wang1, 5), Koji Tokushige1, 5), Nobuhiro Nakano1), Ko Okumura1), Jiro Kitaura1)
1)

Atopy (Allergy) Research Center, Juntendo University Graduate School of Medicine, 2)Department of Otorhinolaryngology, Juntendo University
Graduate School of Medicine, 3)Juntendo University School of Medicine (5th year medical student), 4)Department of Ophthalmology, Juntendo
University Urayasu Hospital, 5)Department of Science of Allergy and Inflammation

51

WS05

Innate lymphocytes

15:30 ~ 16:45 Room E
Chairpersons: Shin-ichiro Fujii, Naoko Satoh-Takayama

Recent advances in the analysis of innate lymphocytes (ILCs, MAIT, NKT, NK and γδT cells) have rapidly deepened ourunderstanding of this field. The innate lymphocytes have a variety of functions; they act as direct effector cells in some cases,
while in other cases, especially under pathological conditions, they may exhibit indirect immunomodulatory effect on otherimmune responses. In this session, we would like to focus on the immunological mechanisms involved in their differentiationand in the pathogenesis of various diseases in order to understand the function or the role of innate lymphocytes in detail. In
addition, therapeutic effects on cancer, infectious diseases, and autoimmune diseases will be discussed. We look forward to alively discussion.

WS05-01-O/P

Self-antigen for mucosal-associated invariant T (MAIT) cells
1, 2)
1, 2)
1, 2)
3)
1, 2)
1, 2)
〇 Emi Ito , Ami Takeyama , Shotaro Mori , Kensuke Shibata , Eri Ishikawa , Masamichi Nagae ,1, 2)
Sho Yamasaki
1)
Department of Molecular Immunology, Research Institute for Microbial Diseases, Osaka University, Suita, Japan, 2)Immunology Frontier
Research Center, Osaka University, Suita, Japan, 3)Department of Microbiology and Immunology, Graduate School of Medicine, Yamaguchi
University, Ube, Japan

WS05-03-O/P

Elucidation of the role of C1orfX in natural killer cells
1, 2)
1, 3, 4)
, Akira Shibuya1, 3, 4)〇 Elfira Amalia Deborah , Tsukasa Nabekura
1)

Department of Immunology, Faculty of Medicine, University of Tsukuba, Japan, 2)Doctoral Program in Medical Science, Graduate School ofComprehensive Human Sciences, University of Tsukuba, Japan, 3)Life Science Center for Survival Dynamics, Tsukuba Advanced Research
Alliance (TARA), University of Tsukuba, Japan, 4)R&D Center for Innovative Drug Discovery, University of Tsukuba, Japan
WS05-05-O/P

Caloric restriction induces cellular quiescence in hepatic ILC1s
1)

1)

1)

2)

2)

〇 Megumi Tatematsu , Akane Fuchimukai , Shunsuke Takasuga , Tsukasa Nabekura , Akira Shibuya ,Takashi Ebihara1)
1)
Department of Medical Biology, Akita University Graduate School of Medicine, 2)Department of Immunology, Faculty of Medicine, and Center
for TARA, University of Tsukuba

WS05-06-O/P

Anatomic and functional compartmentalization of ILC2s in the small intestine
1)

1)

1)

1)

1, 2, 3)

〇 Satoshi Koga , Victor S Cortez , Claire E O’Leary , Hong-Erh Liang , Richard M Locksley
1)

2)

Department of Medicine, University of California San Francisco, San Francisco, California, U.S.A., Department of Microbiology &Immunology, University of California San Francisco, San Francisco, California, U.S.A. , 3)Howard Hughes Medical Institute, University ofCalifornia San Francisco, San Francisco, California, U.S.A.
WS05-07-O/P

ILC2-derived IL-13 contributes to endometriosis exacerbation
1, 2)
1)
1, 2, 3, 4)〇 Kentaro Kubota , Tsuyoshi Kiniwa , Kazuyo Moro
1)

Laboratory for Innate Immune Systems, RIKEN Center for Integrative Medical Sciences (IMS), Kanagawa, Japan, 2)Laboratory for Innate
Immune Systems, Department of Immunology and Microbiology, Osaka University Graduate School of Medicine, Osaka, Japan, 3)Laboratory
for Innate Immune Systems, Osaka University Immunology Frontier Research Center, Osaka, Japan, 4)Laboratory for Innate Immune Systems,
Department of Microbiology and Immunology, Osaka University Graduate School of Frontier Biosciences, Osaka, Japan
WS05-11-O/P

Interleukin-27 supports metabolic adaptation of Natural killer T cells and effector responses
1, 2)
1, 3)
4)
3)
5)
4)
〇 Yasuhiro Kamii , Koji Hayashizaki , Toshio Kanno , Yoshimasa Takahashi , Toshiaki Ohteki , Yusuke Endo ,1, 3)
Yuki Kinjo
1)

Department of Bacteriology, The Jikei University School of Medicine, Tokyo, Japan, 2)Division of Respiratory Diseases, Department of Internal
Medicine, The Jikei University School of Medicine, Tokyo, Japan, 3)Research Center for Drug and Vaccine Development, National Institute of
Infectious Diseases, Tokyo, Japan, 4)Department of Frontier Research and Development, Laboratory of Medical Omics Research, Kazusa DNA
Research Institute, Chiba, Japan, 5)Department of Biodefense Research, Medical Research Institute, Tokyo Medical and Dental University (TMDU),Tokyo, Japan
WS05-14-O/P

CD96 blockade ameliorates imiquimod-induced psoriasis-like dermatitis via suppression of IL-17A
production by dermal gdT cells
1)2)

1, 3, 4)

〇 Kyoko Oh-Oka , Fumie Abe , Akira Shibuya
1), Kazuko Shibuya1, 3)

Department of Immunology, Faculty of Medicine, University of Tsukuba, 2)TNAX Biopharma Corporation, 3)R&D Center for Innovative Drug
Discovery, University of Tsukuba, 4)Life Science Center for Survival Dynamics, Tsukuba Advanced Research Alliance, University of Tsukuba

52

WS05-16-O/P

Regulatory mechanism of RORγt expression in ILC3
1)

2)

1)

1)

1)

〇 Takuma Fukui , Satoshi Kojo , Eriko Sumiya , Shinichi Koizumi , Shinichiro Sawa
1)

Division of Mucosal Immunology, Medical Institute of Bioregulation, Kyushu University, Fukuoka, Japan, 2)Division of Immunology and Stemcell biology, Institute of Medical, Pharmaceutical and Health Sciences, Kanazawa University, Kanazawa, Japan
WS05-17-O/P

Aging alters landscape of pulmonary innate lymphoid cells
1, 2)
1)
3)
3)
3)
〇 Masato Asaoka , Tetsuro Kobayashi , Tommy Walter Terooatea , Jen-Chien Chang , Akiko Minoda ,2)
1, 4, 5)
Hiroki Kabata , Kazuyo Moro
1)
Laboratory for Innate Immune systems, Center for Integrative Medical Sciences, RIKEN, 2)Division of Pulmonary Medicine, Department ofMedicine, Keio University School of Medicine, 3)Laboratory for Cellular Epigenomics, Center for Integrative Medical Sciences, RIKEN,
4)Laboratory for Innate Immune Systems, Department of Microbiology and Immunology, Graduate School of Medicine, Osaka University,
5)
Immunology Frontier Research Center, Osaka University

WS05-18-O/P

A Japanese traditional medicine, Daikenchuto, alleviates colitis by reshaping microbial profiles andenhancing group 3 innate lymphoid cells
1, 2)
1, 3)
1)
1, 2)
1, 2, 3)
〇 Naoko Satoh-Takayama , Zhengzheng Shi , Tadashi Takeuchi , Ritsu Nagata , Hiroshi Ohno
1)

Laboratory for Intestinal Ecosystem, RIKEN Center for Integrative Medical Sciences, Yokohama, Kanagawa, Japan, 2)Immunobiology Laboratory,
Graduate School of Medical Life Science, Yokohama City University, Yokohama, Kanagawa, Japan, 3)Laboratory for Immune Regulation,
Graduate School of Medical and Pharmaceutical Sciences, Chiba University, Chiba, Chiba, Japan

WS06

Autoimmune diseases -Tissue specific-

15:30 ~ 16:45 Room F
Chairpersons: Sachiko Miyake, Shintaro Hojo

Organ-specific autoimmune diseases are characterized by the breakdown of immune tolerance against tissue-specific selfantigen. However, it remains largely unknown how autoreactive T cells and B cells, other immune cells and tissue resident cells
are involved in the disease development and progression. In this session, we would like to discuss the diverse mechanisms oforgan-specific autoimmune diseases including pemphigus, neuromyelitis optica, multiple sclerosis, ankylosing spondylitis, andGraves' ophtalmopathy. We hope that all attendees participate in active discussions. (Each presentation will have 7 min talk + 2
min discussion.)

WS06-01-O/P

Autoantigen-specific B cell-targeted single-cell RNA-seq indicates multiple roles of B cells in pemphigus
1, 2)
1, 3)
4)
1)
1)
〇 Jun Yamagami , Shohei Egami , Takashi Watanabe , Ayano Fukushima-Nomura , Hisashi Nomura ,
1)
4)
1, 3)
Hayato Takahashi , Osamu Ohara , Masayuki Amagai
1)
Department of Dermatology, Keio University School of Medicine, 2)Department of Dermatology, Tokyo Women’s Medical University, 3)Laboratory
for Skin Homeostasis, RIKEN Center for Integrative Medical Sciences, 4)Laboratory for integrative genomics, RIKEN Center for Integrative
Medical Sciences

WS06-02-O/P

Analysis of naïve B cell in neuromyelitis optica spectrum disorders
1)
1)
1)
1, 2)
2)
2)
〇 Shuhei Sano , Soichiro Yoshikawa , Daisuke Noto , Yasunobu Hoshino , Yuji Tomizawa , Kazumasa Yokoyama ,2)
1)
Nobutaka Hattori , Sachiko Miyake
1)

Department of Immunology, Juntendo university, Tokyo, Japan , 2)Department of neurology, Juntendo university, Tokyo, Japan

WS06-03-O/P

Roles of anti-glycolipid antibodies in different animal models of multiple sclerosis with distinct clinicalcourses
1)
1)
1, 2)
1)
3)
1)
〇 Fumitaka Sato , Yumina Nakamura , Kota Moriguchi , Ah-Mee Park , Motoi Kuwahara , Seiichi Omura ,
1)
1)
4)
1)
Sundar Khadka , Ijaz Ahmad , Susumu Kusunoki , Ikuo Tsunoda
1)
Department of Microbiology, Kindai University Faculty of Medicine, Osaka, Japan, 2)Department of Internal Medicine, Japan Self Defense
Forces Hanshin Hospital, Hyogo, Japan, 3)Department of Neurology, Kindai University Faculty of Medicine, Osaka, Japan, 4)Japan Community
Health care Organization (JCHO) Headquarters, Tokyo, Japan

WS06-04-O/P

Progressive multiple sclerosis patient-derived gut bacterial strain accelerates neuronal inflammation via
intestinal Th17 cells
1)

1)

2)

2)

2)

1)

〇 Daiki Takewaki , Wakiro Sato , Hiroaki Masuoka , Masahira Hattori , Wataru Suda , Takashi Yamamura
1)2)

National Center of Neurology and Psychiatry, Kodaira, Japan, RIKEN, Yokohama, Japan53

WS06-05-O/PγδT17 cells in Peyer’s patches acquire the encephalitogenic phenotype through the activation bycommensals and exacerbates autoimmune encephalomyelitis
1)

2)

3)

2)

〇 Seiga Komiyama , Daisuke Takahashi , Tsuneyasu Kaisho , Koji Hase
1)

2)

Division of Biochemistry, Graduate School of Pharmacy, Keio University, Tokyo, Japan, Division of Biochemistry, Faculty of Pharmacy, Keio
University, Tokyo, Japan, 3)Institute of Advanced Medicine, Wakayama Medical University, Wakayama, Japan
WS06-06-O/P

Gut microbiota regulated miRNA disturbs BBB integrity in EAE
1)

1)

2)

1)

1)

1)

〇 Manu Mallahalli , Manu Mallahalli , Hirohiko Hohjoh , Wakiro Sato , Shinji Oki , Takashi Yamamura
1)

2)

Department of Immunology, National Institute of Neuroscience, NCNP, Tokyo, Japan. , Department of Molecular Pharmacology, National
Institute of Neuroscience, NCNP, Tokyo, Japan.
WS06-07-O/P

The role of Dual-specificity phosphatase family in seronegative spondyloarthropathy〇 Ming-Han Chen
Division of Allergy- Immunology- Rheumatology, Department of Medicine, Taipei Veterans General Hospital, Taipei, Taiwan

WS06-08-O/P

Roles of Histone Deacetylases in Orbital Fibroblasts from Graves’ Ophthalmopathy Patients
1)

1)

2)

2)

3)

〇 Supanuch Ekronarongchai , Pimchanok Phankeaw , Chirayus Khawsang , Tanapat Palaga , Preamjit Saonanon ,Vannakorn Pruksakorn3), Nattiya Hirankarn4), P. Martin van Hagen4, 5, 6), Willem A. Dik5), Sita Virakul2)
1)
Medical Microbiology, Interdisciplinary Program, Graduate School, Chulalongkorn University, Bangkok, Thailand., 2)Department ofMicrobiology, Faculty of Science, Chulalongkorn University, Bangkok, Thailand., 3)Department of Ophthalmology, Faculty of Medicine,
Chulalongkorn University, Bangkok, Thailand., 4)Department of Microbiology, Faculty of Medicine, Center of Excellence in Immunology and
Immune Mediated Diseases, Chulalongkorn University, Bangkok, Thailand., 5)Laboratory Medical Immunology, Department of Immunology,
Erasmus MC, University Medical Center, Rotterdam, the Netherlands., 6)Division of Clinical Immunology, Department of Internal Medicine,
Erasmus MC, University Medical Center, Rotterdam, the Netherlands.

WS07

Mucosal-Skin Immunity

15:30 ~ 16:45 Room G
Chairpersons: Eiji Umemoto, Hisako Kayama

The skin and mucosal tissues such as intestine and lung contain high numbers of diverse immune cells. That is reasonable,considering that these tissues are the main routes of invasion of harmful pathogenic microorganisms. Accumulating evidence
has shown that immunological barriers contribute to the tissue homeostasis and pathophysiology of multiple diseases. The aimof this WS is to discuss recent findings on cellular and molecular mechanisms for establishment of the immunological barriers
through interactions between immune cells, non-immune cells, microbiota, and metabolites in the gut, lung, and skin.

WS07-01-O/P

Lactococcus lactis subsp. Cremoris C60 establishes anti-inflammatory intestinal environment by
increasing interleukin-10 producing CD4+ T cells
1, 2, 3)

〇 Noriko Tsuji, Suguru Saito2, 4), Toshio Maekawa1, 2)

1)

Microbiology/ Immune Homeostasis, Dept. Pathology and Microbiology, Nihon University School of Medicine, 2)Cellular and MolecularEngineering, Dept. Life Technology and Science, AIST, 3)Dept. Food Science, Jumonji University, 4)Dept. Dentistry, Faculty of Medicine andDentistry, University of Alberta
WS07-03-O/P

Pyruvate enhances oral tolerance via GPR31
1)

1)

2)

1)

〇 Qizhi Liu , Ryu Okumura , Eiji Umemoto , Kiyoshi Takeda
1)

Department of Microbiology and Immunology, Graduate School of Medicine, Osaka University, 2)Laboratory of Microbiology and Immunology,
School of Pharmaceutical Sciences, University of Shizuoka
WS07-04-O/P

Decoding Interactions between Environmental Small Molecules and Host Receptors in the Gut
1, 2)
1)
1, 2)
〇 Motohiko Kadoki , Daniel Graham , Ramnik Xavier
1)

Broad Institute, Massachusetts, USA, 2)Center for Computational and Integrative Biology, Massachusetts General Hospital, Massachusetts,
USA

WS07-05-O/P

CARS2-dependent sulfur metabolism controls intestinal inflammation by suppressing CD4+ T cellproliferation〇 Shunichi Tayama, Takeshi Kawabe, Kyoga Hiraide, Jing Li, Ziying Yang, Kosuke Sato, Akihisa Kawajiri,
Yuko Okuyama, Naoto Ishii
Department of Microbiology and Immunology, Tohoku University Graduate School of Medicine, Miyagi, Japan54

WS07-06-O/P

Deep profiling identifies a unique tissue resident CD4+ T-cell subset enriched in Crohn’s disease〇 Takehito Yokoi, Mari Murakami, Kiyoshi Takeda
Department of Microbiology and Immunology, Graduate School of Medicine, Osaka University, Osaka, Japan

WS07-07-O/P

Gut-resident innate lymphoid cells regulate lipid metabolism in response to malnutrition.
〇 Takuma Misawa, Shigeo Koyasu
Yokohama City, Kanagawa, Japan, RIKEN IMS Laboratory for Immune Cell Systems

WS07-15-O/P

Mode of action analysis of IL-33 as a mucosal adjuvant
1)

1)

1)

1)

1)

2)

〇 Amane Mukai , Koubun Yasuda , Shiori Egashira , Takumi Adachi , Kazufumi Matsushita , Tomoaki Hoshino ,Etsushi Kuroda1)
1)
Department of Immunology, Hyogo Medical University, School of Medicine, 2)Division of Respirology, Neurology, and Rheumatology,
Department of Medicine, Kurume University School of Medicine.

WS07-16-O/P

Skin-resident ILC1 promote barrier response against mechanical stress1)2)

1, 3, 4)〇 Tetsuro Kobayashi , Aki Minoda , Kazuyo Moro
1)

Innate Immune Systems, IMS, RIKEN, Yokohama, Japan, Cellular Epigenomics, IMS, RIKEN, Yokohama, Japan, 3)Innate Immune Systems,
Osaka University Graduate School of Medicine, Osaka, Japan, 4)Innate Immune Systems, Osaka University Immunology Frontier ResearchCenter, Osaka, Japan
WS07-17-O/P

2)

M2 macrophages generated in the termination phase of skin allergic inflammation display highefferocytic capacity and promote resolution of inflammation
1)

1)

3)

2)

1)

1)

〇 Kensuke Miyake , Junya Ito , Kazufusa Takahashi , Jun Nakabayashi , Shigeyuki Shichino , Hajime Karasuyama
1)

Inflammation, Infection and Immunity Laboratory, Advanced Research Institute, Tokyo Medical and Dental University (TMDU), Tokyo, Japan,
Institute of Education, Tokyo Medical and Dental University (TMDU), 3)Division of Molecular Regulation of Inflammatory and Immune Diseases,
Research Institute of Biomedical Sciences, Tokyo University of Science , Noda, Japan
2)

WS08

Anti SARS-CoV-2 immune responses and Antibody producers

15:30 ~ 16:45 Room H
Chairpersons: Koji Tokoyoda, Kyoko Ochiai

Anti-SARS-CoV-2 immune responses have recently become a hot topic. Under the threat of new viruses, antigen-specificantibodies produced by plasma cells prevent the body from infection. Class switching and affinity maturation of theimmunoglobulin genes in the germinal center are critical for acquiring these antibodies. The molecular mechanism includes
gene regulation, DNA damage repair machinery, cellular metabolism, and cell signaling pathways. This workshop selected
topics related to SARS-CoV-2, Germinal center, Class switch, and Plasma cells.

WS08-01-O/P

Role of germinal center response in the antibody responses against SARS-CoV-2 spike protein
1)

2)

3)

3)

4)

4)

〇 Jumana Khalil , Kosuke Miyauchi , Yuichiro Yamamoto , Kouji Noguchi , Rina Hashimoto , Kazuo Takayama ,Masato Kubo1, 2)
1)Division of Molecular Pathology, Research Institute for Biomedical Science, Tokyo University of Science, Noda, Japan, 2)Laboratory for
Cytokine Regulation, Center for Integrative Medical Sciences, RIKEN, Yokohama, Japan, 3)Department of Pharmaceutical Sciences, Faculty of
Pharmaceutical Sciences, Tokyo University of Science, Noda, Japan, 4)Center for iPS Cell Research and Application, Kyoto University, Kyoto,Japan
WS08-07-O/P

STIM-mediated store-operated calcium entry regulates maintenance and selection of germinal center B
cells
1)
2)
3)
4)
3, 5)
1)
〇 Yutaro Yada , Masanori Matsumoto , Takeshi Inoue , Daisuke Kitamura , Tomohiro Kurosaki , Yoshihiro Baba
1)

Division of Immunology and Genome Biology, Medical Institute of Bioregulation, Kyushu University, Fukuoka, Japan, 2)Department of
Pathology and Rogel Cancer Center, University of Michigan Medical School, Ann Arbor, MI, USA., 3)Laboratory for Immune Response
Dynamics, WPI Immunology Frontier Research Center, Osaka University, Suita, Osaka, Japan., 4)Division of Molecular Biology, ResearchInstitute for Biomedical Sciences, Tokyo University of Science, Noda, Chiba, Japan, 5)Laboratory for Lymphocyte Differentiation, RIKEN Center
for Integrative Medical Sciences (IMS), Yokohama, Kanagawa, Japan.

55

WS08-09-O/P

The effect of iron metabolism on antibody production of B cell
1)

1)

1)

1)

1)

1)

〇 Mayuko Shimoda , Mayumi Niimura , Yuki Takeshima , Chanida Thinyakul , Narumi Harada , Saisai Liu ,Toshiro Moroishi1, 2)
1)
Department of Cell Signaling and Metabolic Medicine, Faculty of Life Sciences, Kumamoto University, 2)Center for Metabolic Regulation of
Healthy Aging, Faculty of Life Sciences, Kumamoto University

WS08-10-O/P

HNRNPU Promotes Antibody Class Switch Recombination through NHEJ and R-loop Regulation at the IgH
locus
1, 2)
1)
3)
1)
4)
1)
〇 Ahmed M. Refaat , Nasim A. Begum , Afzal Husain , Mikiyo Nakata , Hidetaka Kosako , Tasuku Honjo
1)

Department of Immunology and Genomic Medicine, Center for Cancer Immunotherapy and Immunobiology, Kyoto University Graduate Schoolof Medicine, Kyoto, Japan, 2)Zoology Department, Faculty of Science, Minia University, El-Minia, Egypt, 3)Department of Biochemistry, Faculty ofLife Sciences, Aligarh Muslim University, Aligarh, Uttar Pradesh, India, 4)Division of Cell Signaling, Institute of Advanced Medical Sciences, The
University of Tokushima, Tokushima, Japan
WS08-11-O/P

NOP16, a novel regulator of histone modification, regulates B-cell class switch recombination〇 Yohana Mtali, Ken Takashima, Atsushi Irie, Hiroyuki Oshiumi
Department of Immunology, Graduate school of medical science, Kumamoto University, Kumamoto, Japan

WS08-13-O/P

Novel strategy for treatment of allergic diseases by regulation of IgA class switching
1)

1)

2)

〇 Naoki Morita , Reiko Shinkura , Hirotatsu Kojima
1)

Laboratory of Immunology and Infection Control, Institute for Quantitative Biosciences, The University of Tokyo, 2)Drug Discovery Initiative,
Graduate School of Pharmaceutical Sciences, The University of Tokyo

WS08-14-O/P

Identification of IgA autoantibodies against glomerular mesangial cells and the target autoantigen using
an IgA nephropathy mouse model
1, 2)
2)
2)
1)
2)
1)
〇 Yoshihito Nihei , Kei Haniuda , Mizuki Higashiyama , Hiroyuki Iwasaki , Shohei Asami , Yusuke Suzuki ,2)Daisuke Kitamura
1)

Department of Nephrology, Juntendo University Faculty of Medicine, Tokyo, Japan., 2)Division of Cancer Cell Biology, Research Institute for
Biomedical Sciences (RIBS), Tokyo University of Science, Noda, Japan.
WS08-16-O/P

Immunoglobulin A deficiency breaks immunological and neurological homeostasis〇 Takahiro Adachi
Medical Research Institute, Tokyo Medical and Dental University, Japan

WS08-19-O/P

The regulation of B cell chromatin by a non-histone chromatin protein PC4 and its interacting transcription
factors〇 Kyoko Ochiai, Kazuhiko Igarashi
Tohoku University Graduate School of Medicine

WS08-20-O/P

Genetic tracing of plasma cells reveals cellular dynamism during entry to long-lived compartment
1, 2)
2, 3)
2, 4)
2, 3)
2, 3)
2, 3)
〇 Takuya Koike , Kentaro Fujii , Kohei Kometani , Shinya Yari , Junichi Kikuta , Masaru Ishii ,2)
1, 2)
Tomohiro Kurosaki , Wataru Ise
1)
Center for Infectious Disease Education and Research, Osaka University, Osaka, Japan, 2)WPI Immunology Frontier Research Center, Osaka
University, Osaka, Japan, 3)Graduate School of Medicine and Frontier Biosciences, Osaka University, Osaka, Japan, 4)Center for iPS Cell
Research and Application, Kyoto University, Kyoto, Japan

WS08-21-O/P

In vivo predominant immunoglobulin secretion in the bone marrow IgG-secreting plasma cells〇 Shogo Tsuda, Harumi Sasaki, Akihiko Murata, Koji Tokoyoda
Division of Immunology, School of Life Science, Faculty of Medicine, Tottori University, Yonago, Japan

WS08-22-O/P

Lymphocyte infiltration into liver was enhanced in high-fat diet-loaded LDL receptor and MD-1 doubledeficient mice
〇 Sachiko Akashi-Takamura, Mrityunjoy Biswas, Susumu Tomono, Tatsuya Yamazaki, Masanori Inui,
Sajid Iftekhar Chowdhury
Department of Microbiology and Immunology, Aichi Medical University, School of Medicine, Nagakute, Japan

56

WS09

Molecular and cellular diversity of allergic disease

15:30 ~ 16:45 Room I
Chairpersons: Yumi Matsuoka-Nakamura, Yosuke Kurashima

The symphony of the allergy-related molecular and cellular interaction leads to the chronic allergic inflammation occurring in
the various tissues and resulting in the atopic dermatitis, contact hypersensitivity, allergic conjunctivitis etc. Thus, elucidationof the complexity of diverse cellular interplay which orchestrates allergic reaction is critically important to develop the next
generation of the novel first line treatment.In this session, we would like to discuss pathophysiology of allergic inflammation,
especially focus on the complex interplay among various molecular and cellular interplay of allergic disease.

WS09-01-O/P

Spontaneous dermatitis associated with elevated sebaceous lipid production in Tmem79-deficient mice
1, 2)
1, 2)
1, 2)
1, 2)
3, 4)
5, 6)
〇 Ari Morimoto , Keitaro Fukuda , Yoshihiro Ito , Hiroshi Kawasaki , Eiryo Kawakami , Makoto Arita ,7)
1, 2, 8)1, 2)Haruhiko Koseki , Takeshi Matsui, Masayuki Amagai
1)
Department of Dermatology, Keio University School of Medicine, Tokyo, Japan, 2)Laboratory for Skin Homeostasis, RIKEN Center for Integrative
Medical Sciences, Yokohama, Japan, 3)Advanced Data Science Project (ADSP), RIKEN Information R&D and Strategy Headquarters, Yokohama,Japan, 4)Artificial Intelligence Medicine, Graduate School of Medicine, Chiba University, Chiba, Japan, 5)Division of Physiological Chemistry andMetabolism, Faculty of Pharmacy, Keio University, Tokyo, Japan, 6)Laboratory for Metabolomics, RIKEN Center for Integrative Medical Sciences,
Yokohama, Japan, 7)Laboratory for Developmental Genetics, RIKEN Center for Integrative Medical Sciences, Yokohama, Japan, 8)Laboratory for
Evolutionary Cell Biology of the Skin, School of Bioscience and Biotechnology, Tokyo University of Technology, Hachioji, Japan

WS09-02-O/P

Elucidation of the pathogenesis of spontaneous dermatitis in Foxp3 Bcl6 cDKO mice
1)

2)

1)

〇 Yuki Tai , Shuhei Ogawa , Yohsuke Harada
1)

Laboratory of Pharmaceutical Immunology, Faculty of Pharmaceutical Sciences, Tokyo University of Science, Chiba, Japan, 2)Division ofIntegrated Research, Research Institute for Biomedical Sciences, Tokyo University of Science, Chiba, Japan
WS09-03-O/P

T cell-specific deletion of Pgam1, a glycolytic enzyme, ameliorates the symptoms of allergic contact
dermatitis in mice
1)

1, 2)

〇 Miyuki Omori-Miyake , Masakatsu Yamashita
1)

Dept. of Infections and Host Defenses, Ehime University Graduate School of Medicine, 2)Dept. of Immunology, Ehime University Graduate
School of Medicine
WS09-04-O/P

Decomposition of Atopic dermatitis skin RNA-seq data reveals diverse immune pathways in its
pathogenesis
1)
1, 2)
1)
3)
1)
〇 Ayano Fukushima-Nomura , Hiroshi Kawasaki , Keiji Tanese , Eiryo Kawakami , Masayuki Amagai
1)

Department of Dermatology, Keio University School of Medicine, 2)RIKEN Center for Integrative Medical Sciences, 3)RIKEN Advanced Data
Science Project
WS09-05-O/P

Inflammatory and pruritogenic actions of Oncostatin-M (OSM) in the pathogenesis of atopic dermatitis
1, 2, 3), Hiroshi Kawasaki1, 2, 3), Sonoko Takahashi4), Sotaro Ochiai4), Takaharu Okada4),〇 Tomohiro Miyai
2, 5)
Masayuki Amagai , Haruhiko Koseki1, 6)
1)

Laboratory for Developmental Genetics, RIKEN IMS, Yokohama, Japan, 2)Department of Dermatology, Keio University School of Medicine,Tokyo, Japan, 3)Development Theme for Atopic Dermatitis Therapeutics, RIKEN DMP, Yokohama, Japan, 4)Laboratory for Tissue Dynamics,
RIKEN IMS, Yokohama, Japan, 5)Laboratory for Skin Homeostasis, RIKEN IMS, Yokohama, Japan, 6)Department of Cellular and Molecular
Medicine, Chiba University School of Medicine, Chiba, Japan
WS09-06-O/P

Skin treatment with detergent induces dermatitis with H1 antihistamine-refractory itch and upregulates
IL-4 and Th17/Th22 cytokine gene expression in C57BL/6 mice
1)
1, 2)
1, 2)
1, 2)
3)
2)
〇 Seiji Kamijo , Yurie Masutani , Toru Kimitsu , Tomoko Yoshimura , Saori Ichikawa , Takasuke Ogawa ,Mitsutoshi Tominaga4), Hajime Suto1), Kenji Takamori4), Shigaku Ikeda1, 2), Ko Okumura1), Toshiro Takai1)
1)

Atopy (Allergy) Research Center, Juntendo University Graduate School of Medicine, 2)Department of Allergology and Dermatology, Juntendo
University Graduate School of Medicine, 3)Department of Materials and Biological Sciences, Japan Women’s University, 4)Juntendo Itch ResearchCenter (JIRC), Juntendo University Graduate School of Medicine

57

WS09-07-O/P

Mead acid (5,8,11-eicosatrienoic acid) inhibits retinol-induced irritant contact dermatitis through PPARαmediated pathway
1)
1, 2)
1, 3)
1)
1)
4)
5)
〇 Azusa Saika , Prabha Tiwari , Takahiro Nagatake , Koji Hosomi , Eri Node , Tetsuya Honda , Kenji Kabashima ,1)
Jun Kunisawa
1)

Laboratory of Vaccine Materials, Center for Vaccine and Adjuvant Research, and Laboratory of Gut Environmental System, Collaborative
Research Center for Health and Medicine, National Institutes of Biomedical Innovation, Health and Nutrition (NIBIOHN), Ibaraki, Osaka,
2)
Laboratory for Transcriptome Technology, RIKEN Center for Integrative Medical Sciences, Yokohama, Kanagawa, 3)Laboratory of Functional
Anatomy, Department of Life Sciences, School of Agriculture, Meiji University, Kawasaki, Kanagawa, 4)Department of Dermatology, Hamamatsu
University School of Medicine, Hamamatsu, Shizuoka, 5)Department of Dermatology, Graduate School of Medicine, Kyoto University, Kyoto,
Kyoto
WS09-08-O/P

DOCK2 is essential for MRGPRX2/B2-mediated mast cell degranulation and drug-induced anaphylaxis〇 Kazufumi Kunimura, Yoshinori Fukui
Division of Immunogenetics, Medical Institute of Bioregulation, Kyushu University, Fukuoka, Japan

WS09-09-O/P

Pollen shells promote allergic conjunctivitis through inducible goblet cell-associated antigen passage
1, 2, 3), Tomoaki Ando1), Yasuharu Kume1, 2, 3), Saaya Fukase1, 2, 3), Moe Matsuzawa1, 2, 3), Kumi Izawa1),〇 Meiko Kimura
1)
Ayako Kaitani , Nobuhiro Nakano1), Ko Okumura1), Akira Murakami3), Nobuyuki Ebihara2, 3), Jiro Kitaura1, 4)
1)
Atopy (Allergy) Research Center, Juntendo University Graduate School of Medicine (Tokyo, Japan), 2)Department of Ophthalmology, Juntendo
University Urayasu Hospital (Chiba, Japan), 3)Department of Ophthalmology, Juntendo University Graduate School of Medicine (Tokyo, Japan),4)
Department of Science of Allergy and Inflammation, Juntendo University Graduate School of Medicine (Tokyo, Japan)

December 8
WS10

T cell function and diseases-1 (Disease models and SARS-CoV-2)

14:05 ~ 15:20 Room B
Chairpersons: Masaaki Murakami, Junko Morimoto

T cells require proper activation and differentiation processes for host defense against pathogens. Multiple mechanisms,
including TCR signaling, costimulatory and inhibitory molecules, cytokines, and metabolites exert key controls on T cellfunction. A comprehensive understanding of the molecular mechanisms laying the T cell activation and differentiation areimportant subjects for future therapeutic application as well. In this session, we will discuss several topics on T cell signaling
and T cell subsets related to CNS and skin diseases and inflammmation against SARS-CoV-2. We hope active participation anddiscussion in oral and poster presentations. [Each presentation is expected to finish within 7 minutes followed by 3 minutes of
discussion.]

WS10-01-O/P

CD4+ skin-resident memory T cells persist in CD68+ cellular niches〇 Akihiko Murata, Momoka Wakazuki, Koji Tokoyoda
Division of Immunology, Department of Molecular and Cellular Biology, School of Life Science, Faculty of Medicine, Tottori University, Tottori,
Japan

WS10-02-O/P

A gain-of-function mutation of immunoreceptor DNAM-1 exacerbates CD4+ T cell-mediated autoimmune
inflammation
1, 2)
1, 2)
1, 3)
4)
1, 3, 5),
〇 Rikito Murata , Shota Kinoshita , Kenshiro Matsuda , Atsushi Kawaguchi , Akira Shibuya
1, 5)Kazuko Shibuya
1)

Department of Immunology, Faculty of Medicine, University of Tsukuba, 2)Ph.D. Program in Human Biology, University of Tsukuba, 3)LifeScience Center for Survival Dynamics, Tsukuba Advanced Research Alliance (TARA), University of Tsukuba, 4)Infection Biology, Faculty of
Medicine, University of Tsukuba , 5)R&D Center for Innovative Drug Discovery, University of Tsukuba
WS10-03-O/P

NRP1 marks a pathogenic self-reactive Th subset in autoimmune disease
1)

2)

1)

1)

1)

〇 Ben Raveney , Shohei Hori , Wakiro Sato , Takashi Yamamura , Shinji Oki
1)

2)

Department of Immunology, National Institute of Neuroscience, NCNP, Kodaira, Tokyo, Japan, Laboratory for Immunology and Microbiology,
Graduate School of Pharmaceutical Sciences, University of Tokyo, Japan
WS10-04-O/P

Role of γδ T cells in antigen specific CD4+ T cell response to Plasmodium chabaudi infection
1)

1)

2)

1)

1, 2, 3)

〇 Yarob Ibraheem , Ganchimeg Bayarsaikhan , Maria Lourdes Macalinao , Kazumi Kimura , Katsuyuki Yui
Shin-Ichi Inoue1)

1)
Division of Immunology, Department of Molecular Microbiology and Immunology, Graduate School of Biomedical Sciences, Nagasaki
University, 2)School of Tropical Medicine and Global Health, Nagasaki University, 3)Institute of Tropical Medicine, Nagasaki University

58,

WS10-05-O/P

Cytotoxic CD8+ T cells simultaneously expressing GZMA, GZMB and Perforin regulate COVID-19 severity
1, 2)
3)
1)
1, 2)
4)
5)
〇 Takuto Nogimori , Koichiro Suzuki , Yuji Masuta , Ayaka Washizaki , Hidenori Kanda , Minoru Takada ,
6)
6)
1, 2)
3, 7, 8)1, 2, 6, 9, 10)
Shohei Minami , Takeshi Kobayashi , Shokichi Takahama , Yasuo Yoshioka, Takuya Yamamoto
1)
Laboratory of Immunosenescence, Center for Vaccine and Adjuvant Research, National Institutes of Biomedical Innovation, Health andNutrition, Osaka, Japan, 2)Research Institute for Microbial Diseases, Osaka University, Osaka, Japan, 3)The Research Foundation for Microbial
Diseases of Osaka University (BIKEN), Osaka, Japan, 4)KINSHUKAI, Hanwa Memorial Hospital, Osaka, Japan, 5)KINSHUKAI, Hanwa The Second
Senboku Hospital, Osaka, Japan, 6)Department of Virology, Research Institute for Microbial Diseases, Osaka University, Osaka, Japan, 7)Vaccine
Creation Group, BIKEN Innovative Vaccine Research Alliance Laboratories, Research Institute for Microbial Diseases, Osaka University, Osaka,
Japan, 8)Institute for Open and Transdisciplinary Research Initiatives, Osaka University, Osaka, Japan, 9)Laboratory of Aging and Immune
Regulation, Graduate School of Pharmaceutical Sciences, Osaka University, Osaka, Japan, 10)Department of Virology and Immunology, Graduate
School of Medicine, Osaka University, Osaka, Japan

WS10-06-O/P

T cell responses induced by SARS-Cov-2 mRNA vaccination are associated with clonal replacement
1, 2)
3)
1)
3)
3)
〇 Hiroyasu Aoki , Masahiro Kitabatake , Shigeyuki Shichino , Atsushi Hara , Noriko Ouji-Sageshima ,Toshihiro Ito3), Kouji Matsushima1), Satoshi Ueha1)1)Division of Molecular Regulation of Inflammatory and Immune Diseases, Research Institute for Biomedical Sciences, Tokyo University of
Science, Chiba, Japan., 2)Department of Hygiene, Graduate School of Medicine, The University of Tokyo., 3)Department of Immunology, Nara
Medical University, Nara, Japan.
WS10-07-O/P

In vivo generation of designer APCs with mRNA regulates T cell immune responses
1, 2)
1)
1)
1)
1, 2)
〇 Tomoyoshi Yamano , Shota Imai , Toan Le , Xiabing Lyu , Rikinari Hanayama
1)
Department of Immunology, Graduate School of Medical Sciences, Kanazawa University, 2)WPI Nano Life Science Institute (NanoLSI),
Kanazawa University

WS11

Tumor Immunotherapy

14:05 ~ 15:20 Room C
Chairpersons: Hiroaki Ikeda, Kanako Shimizu

Recently, tumor immunotherapies such as immune checkpoint inhibitors (ICIs) and CAR-T cell therapy have been applied toclinical treatment of cancer patients. However, patients benefitted from these treatments are still limited, suggesting the needs
to better understand the mechanism of the obstacles and to develop novel and effective cancer immunotherapy that overcome
the problems. In this session, we will discuss about new approaches to overcome recent limits in adoptive immunotherapy suchas CAR-T and TCR-T cell therapy as well as ICI therapies. The suppressive mechanism such as Tregs, co-inhibitory molecules,
and new insights in B cells and antibody in tumor immunity will be also presented. We hope these presentations will stimulate
the audience resulting in exploration of the new strategy to develop novel and effective tumor immunotherapies.

WS11-04-O/P

Exhaustion-resistant CAR-T cells by overexpressing dominant negative form of NR4A factors for thetreatment of solid tumors〇 Makoto Ando, Akihiko Yoshimura
Department of Microbiology and Immunology, Keio University School of Medicine, Tokyo, Japan

WS11-05-O/P

Development of CART cell therapy against T cell malignancies
1)

2)

1)

〇 Keisuke Watanabe , Carl June , Hiroyoshi Nishikawa
1)

National Cancer Research Center Research Institute Division of Cancer Immunology, Tokyo Japan, 2)Center for Cellular Immunotherapies,
Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA
WS11-06-O/P

A novel chimeric cytokine receptor-engineered CAR-T cells achieve both potent cytotoxicity and reduced
cytokine release syndrome〇 Toshiaki Yoshikawa, Yuki Kagoya
Aichi Cancer center, Aichi, Japan

WS11-07-O/P

Targeting poor prognosis acute myeloid leukemia with CD25-targeted chemokine receptor expressing
CAR T cell therapy
1, 2)
1)
3)
3)
1)
〇 Ari Itoh-Nakadai , Mariko Murasawa-Tomizawa , Masashi Matsuda , Haruhiko Koseki , Fumihiko Ishikawa
1)
Laboratory for Human Disease Models, IMS, Riken , Yokohama, Japan, 2)Hygiene & public Health, Nippon Medical School, Tokyo, Japan, 3)
Developmental Genetics, IMS,RIKEN, Yokohama, Japan59

WS11-09-O/P

Engineering immune cell network with advanced split CAR system
1, 2, 3)〇 Atsushi Okuma
1)

Department of Biomedical Engineering, Boston University, 2)Biological Design Center, Boston University, 3)Current affiliation; Center for
Exploratory Research, Hitachi, Ltd
WS11-10-O/P

Generation of genetically engineered TCR-T cells from self-renewing multipotent progenitor cells〇 Tsukasa Shigehiro, Tomokatsu Ikawa
Research Institute for Biomedical Sciences, Tokyo University of Science, Chiba, Japan

WS11-11-O/P

Harnessing arginine metabolism to overcome hyperthermia-induced metabolic dysfunction of CAR T-cells〇 Taisuke Kondo, Justyn Dusold, Naomi Taylor
National Cancer Institute, National Institutes of Health, Maryland, USA

WS11-14-O/P

Aging-associated and CD4 T cell-dependent ectopic CXCL13 activation predisposes to anti-PD-1 therapyinduced adverse events
1)

2)

3)

2)

4)

〇 Hirotake Tsukamoto , Yoshihiro Komohara , Yusuke Tomita , Yuji Miura , Takanobu Motoshima ,Kosuke Imamura3), Toshiki Kimura3), Yukio Fujiwara2), Hiromu Yano2), Tomomi Kamba4), Takuro Sakagami3),
Hiroyuki Oshiumi5)
1)

Division of Clinical Immunology and Cancer Immunotherapy, Center for Cancer Immunotherapy and Immunobiology, Graduate Schoolof Medicine, Kyoto University, 2)Department of Cell Pathology, Graduate School of Medical Sciences, Faculty of Life Sciences, Kumamoto
University, 3)Department of Respiratory Medicine, Graduate School of Medical Sciences, Faculty of Life Sciences, Kumamoto University,
4)
Department of Urology, Graduate School of Medical Sciences, Faculty of Life Sciences, Kumamoto University, 5)Department of Immunology,
Graduate School of Medical Sciences, Faculty of Life Sciences, Kumamoto University
WS11-20-O/P

A TGF-β milieu molecule on Tregs orchestrates cancer progression in the lung
〇 Qiao Gou, Hiroyuki Takaba, Hiroshi Takayanagi
Department of Immunology, The University of Tokyo, Tokyo, Japan

WS11-23-O/P

Clonal expanded IgG-producing plasma cells triggered by Tfh cells are associated with better survival inendometrial cancer
1)

1)

1)

2)

2)

2)

〇 Mayu Fujioka , Shusei Fujioka , Hiroyuki Yoshitomi , Masayo Ukita , Haruka Suzuki , Junzo Hamanishi ,Yasuhide Takeuchi3), Sachiko Minamiguchi3), Hiroaki Ito3), Masaki Mandai2), Hideki Ueno1)
1)

Department of Immunology, Kyoto University, Kyoto, Japan, 2)Department of Gynecology and Obstetrics, Kyoto University, Kyoto, Japan,
Department of Diagnostic Pathology, Kyoto University, Kyoto, Japan

3)

WS12

Infection and Immunity II

14:05 ~ 15:20 Room D
Chairpersons: Taro Kawai, Miwa Sasai

Infection of microbes such as viruses, bacteria, fungi and parasites induces host immune responses. Activation of host innate
and adaptive immune cells by various host receptors and the subsequent signaling pathways are important for exclusion andelimination of the infecting microbes. Recent advances in understanding molecular mechanisms of how host innate and adaptive
immune receptors recognize microbe infection are highly in progress. In this workshop, studies such as immune responses,
immunological memory, macrophages, interferon and various signaling molecules in terms of pathogenic microbe infection are
particularly focused.

WS12-04-O/P

Delayed antigen-specific CD4+ T-cell induction correlates with lower antibody responses and fewer
adverse effects to SARS-CoV-2 mRNA vaccination in older adults
1, 2)
1, 3)
〇 Norihide Jo , Yoko Hamazaki
1)

Department of Life Science Frontiers, Center for iPS Cell Research and Application (CiRA), Kyoto University, 2)Alliance Laboratory for
Advanced Medical Research, Graduate school of Medicine, Kyoto University, 3)Laboratory of Immunobiology, Graduate school of Medicine,
Kyoto University
WS12-06-O/P

The underlying mechanism of the deterioration in obese patients with COVID-19
1, 2)
1, 2)
1, 2)
1)
1)
1, 2)
〇 Tadashi Hosoya , Seiya Oba , Yoji Komiya , Daisuke Kawata , Mari Kamiya , Hideyuki Iwai ,
2)
2)
2)
2)
3)
Sho Miyamoto , Takayuki Kanno , Akira Ainai , Tadaki Suzuki , Hideki Hasegawa , Shinsuke Yasuda1)
1)

Department of Rheumatology, Tokyo Medical and Dental University, 2)Department of Pathology, National Institute of Infectious Diseases,
Center for Influenza and Respiratory Virus Research, National Institute of Infectious Diseases

3)60

WS12-07-O/P

Elevated Myl9 reflects the Myl9-containing microthrombi in SARS-CoV-2-induced lung exudative
vasculitis and predicts COVID-19 severity〇 Chiaki Iwamura, Kiyoshi Hirahara, Masahiro Nemoto, Kaori Tsuji, Miki Onoue, Akane Kurosugi, Atsuhi Sasaki,
Toshinori Nakayama
Chiba Univeristy

WS12-12-O/P

The Vi capsular polysaccharide of Salmonella Typhi promotes macrophage phagocytosis by binding thehuman C-type lectin DC-SIGN
1, 2)
2)
2)
〇 Hirotaka Hiyoshi , Lillian F. Zhang , Andreas J. Bäumler
1)

Institute of Tropical Medicine, Nagasaki University, 2)University of California at Davis

WS12-16-O/P

The C-type lectin receptor Dcir1 counterbalances the antifungal response against Aspergillus fumigatus
infection〇 Fabio Yoshikawa, Shinobu Saijo
Medical Mycology Research Center, Chiba University, Chiba, Japan

WS12-18-O/P

Transcriptomic analysis of the olfactory bulb during experimental cerebral malaria (ECM)
1, 2)
1, 3)
1, 2, 3)
〇 Julia Matsuo-Dapaah , Michelle Sue Jann Lee , Cevayir Coban
1)
Division of Malaria Immunology, Institute of Medical Science (IMSUT), University of Tokyo, 2)Graduate School of Medicine, University ofTokyo, 3)International Vaccine Design Center, Institute of Medical Science (IMSUT), University of Tokyo

WS12-20-O/P

Identification of leukocyte immunoglobulin-like receptor A1 (LILRA1) as a specific receptor for Aspergillus
fumigatus conidia〇 Yasunobu Miyake, Hiroki Yoshida
Division of Molecular and Cellular Immunoscience, Department of Biomolecular Sciences, Faculty of Medicine, Saga University

WS12-23-O/P

Antiviral innate immune responses are regulated by a lipid metabolism via expression of unusual type I
IFN subtypes〇 Tasuku Nishimura, Takahisa Kouwaki, Hiroyuki Oshiumi
Department of Immunology, Faculty of Life Sciences, Kumamoto University, Kumamoto, Japan

WS13

B cell Development and Activation

14:05 ~ 15:20 Room E
Chairpersons: Makoto Tsuiji, Saya Moriyama

Autoimmune disease is a condition arising from an abnormal immune response to self. These diseases provide us withmuch insight into B cell development and activation. Furthermore, findings on the responses to T cell-independent antigens,adjuvants, and repertoire analysis of antibodies are also crucial for B cell regulation. Therefore, this workshop selected topics
related to Autoimmune diseases, B cell development, T-independent responses, adjuvants, and Repertoire.

WS13-01-O/P

Transcriptional signature of anergy in naturally occurring self-reactive B cells
1, 2)
2)
2)
2)
〇 Ryosuke Hiwa , John P. Huizar , James L. Mueller , Julie Zikherman
1)
Department of Rheumatology and Clinical Immunology, Kyoto University Hospital, Kyoto, Japan, 2)Division of Rheumatology, Rosalind Russell
and Ephraim P. Engleman Arthritis Research Center, Department of Medicine, UCSF, San Francisco, CA, USA

WS13-03-O/P

Immunological functions of Castor1 in B cells
1)
1)
1, 2)
1)
〇 Takeshi Kusuda , Toshihiko Komai , Tomohisa Okamura , Keishi Fujio
1)
Department of Allergy and Rheumatology, Graduate School of Medicine, The University of Tokyo, 2)Department of Functional Genomics and
Immunological Diseases, Graduate School of Medicine, The University of Tokyo

WS13-04-O/P

The COMMD3/8 complex is a potential therapeutic target for autoimmune diseases
1)
1, 2)
1, 2, 3)〇 Taiichiro Shirai , Akiko Nakai , Kazuhiro Suzuki
1)
Laboratory of Immune Response Dynamics, WPI Immunology Frontier Research Center, Osaka University, Suita, Osaka, Japan, 2)Department of
Immune Response Dynamics, Research Institute for Microbial Diseases, Osaka University, Suita, Osaka, Japan, 3)Center for Infectious Disease
Education and Research, Osaka University, Suita, Osaka, Japan61

WS13-05-O/P

IL-15-producing splenic B cells play pathogenic roles in the development of autoimmune hepatitis
1, 2)
1)
1)
〇 Sota Fujimori , Nobuhiro Nakamoto , Takanori Kanai
1)

Division of Gastroenterology and Hepatology, Department of Internal Medicine, Keio University School of Medicine, 2)Research Unit
Immunology & Inflammation, Innovative Research Division, Mitsubishi Tanabe Pharma Corporation
WS13-06-O/P

Essential function for EMC1(ER membrane complex subunit1) in Ca2+ influx and B cell development
1)

2)

2)

1)

〇 Kazuhiko Kawata , Chie Kikutake , Mikita Suyama , Yoshihiro Baba
1)

Division of Immunology and Genome Biology, Medical Institute of Bioregulation, Kyushu University, Fukuoka, Japan, 2)Division of
Bioinformatics, Medical Institute of Bioregulation, Kyushu University, Fukuoka, Japan

WS13-07-O/P

miR-195 accomplishes B cell development without EBF1 by regulating transcription factors.
1)

2)

3)

3)

4)

5)

〇 Yuji Miyatake , Tomokatsu Ikawa , Ken-Ichi Hirano , Katsuto Hozumi , Kiyoshi Ando , Hiroshi Kawamoto ,Ai Kotani1)
1)
Department of Advanced Medical Science, Tokai University School of Medicine, Isehara, Japan, 2)RIKEN Research Center for Allergy and
Immunology, Yokohama, Japan, 3)Department of Immunology, Tokai University School of Medicine, Isehara, Japan, 4)Department of Hematology,
Tokai University School of Medicine, Isehara, Japan, 5)Department of Immunology, Institute for Frontier Life and Medical Science, Kyoto
University, Kyoto, Japan

WS13-10-O/P

The mechanism for T cell-independent B cell activation by the bacterial polysaccharide dexstran
1, 2)
1)
1)
1)
1)
2)
〇 Yuming Huang , Kana Matsumura , Nazim Medzhidov , Toshitaro Takata , Miao Tang , Takeshi Tsubata
1)
Department of Immunology, Medical Research Institute, Tokyo Medical and Dental University., 2)Department of Pathology, Nihon University
School of DentistryWS13-11-O/P

The importance of IL-1 - IL-1 receptor signaling to T-cell-independent type 2 responses〇 Mari Tenno, Tang Xuyang, Takumi Umezu, Daisuke Kitamura
Division of Cancer Cell Biology, Research Institute for Biomedical Sciences (RIBS) Tokyo University of Science

WS13-13-O/P

Adjuvant Activity of Chemically Synthesized Alcaligenes Lipid A to Augment Immune Responses against
Haemophilus Influenzae Type B Conjugate Vaccine
1, 2)
1)
2)
1, 2)
1, 2)
2)
2)
〇 Zilai Liu , Koji Hosomi , Atsushi Shimoyama , Ken Yoshii , Xiao Sun , Haruki Yamaura , Davie Kenneth ,1)
1, 3)
4, 5, 6)2)
1, 2, 4, 7, 8)Azusa Saika , Takahiro Nagatake , Hiroshi Kiyono, Koichi Fukase , Jun Kunisawa
1)

National Institutes of Biomedical Innovation, Health, and Nutrition, Osaka, Japan, 2)Osaka University, Osaka, Japan, 3)Meiji University, Tokyo,
Japan, 4)The University of Tokyo, Tokyo, Japan, 5)University of California San Diego, California, United States, 6)Chiba University, Chiba, Japan,
7)
Kobe University, Hyōgo, Japan, 8)Waseda University, Tokyo, Japan
WS13-14-O/P

Recombinant anti-RP105 provides an adjuvant effect for gene immunization against influenza〇 Tatsuya Yamazaki, Mrityunjoy Biswas, Masanori Inui, Susumu Tomono, Sachiko Akashi-Takamura
Department of Microbiology and Immunology, Aichi Medical University, School of Medicine, Aichi, Japan

WS13-17-O/P

Evaluation of immune response induced by influenza vaccines using the repertoire analysis of variablegenes of antibodies
1)

1)

1)

2)

3)

1)

〇 Hinako Ohkusa , Mizuki Uryu , Shinichi Fujihara , Kayoko Sato , Hideki Asanuma , Makoto Tsuiji
1)

2)

Department of Microbiology, Hoshi University School of Pharmacy and Pharmaceutical Sciences, Tokyo, Japan., Department of Virology 3,
National Institute of Infectious Diseases, Tokyo, 3)Center for Influenza and Respiratory Virus Research, National Institute of Infectious Diseases,
Tokyo, Japan

62

WS14

Innate immunity (1) Innate inflammation and disease

14:05 ~ 15:20 Room F
Chairpersons: Hideyuki Yanai, Takashi Satoh

Recent studies of innate immunity clearly indicate that there are various exogenous and endogenous ligands such as pathogen
associated molecular patterns (PAMPs), danger-associated molecular patterns (DAMPs), microbiota metabolite and lipid, andthey are involved in induction of acute or chronic inflammation. Also, such inflammation is associated with homeostasis ordevelopment/exacerbation of various diseases as microbial and virus infection, tumor progression, fibrosis, neural disorder andso on. In addition, drugs targeting these phenomena are also being developed. Thus, this research field is active and growing
rapidly. In this workshop, we will focus on inflammation and disease related to innate immunity. We would like to expect youractive participation and fruitful discussion in this session.

WS14-03-O/P

HMGB1 in cancer and inflammatory diseases〇 Hideyuki Yanai
Research Center for Advanced Science and Technology, The University of Tokyo

WS14-06-O/P

Short-term epigenetic memory in monocytes induced by BNT162b2 mRNA vaccine〇 Yuta Yamaguchi, Yasuhiro Kato, Atsushi Kumanogoh
Department of Respiratory Medicine and Clinical Immunology, Osaka University Graduate School of Medicine, Suita, Japan.

WS14-09-O/P

Molecular mechanisms by which mTORC1 drives granulomas〇 Ryosuke Hiranuma, Ryota Sato, Kensuke Miyake
Division of Innate Immunity, Department of Microbiology and Immunology, The Institute of Medical Science, The University of Tokyo

WS14-11-O/P

Impact of changes of the gut microbiota on the development of liver inflammation and fibrosis in a novel
dietary mouse model of non-alcoholic steatohepatitis, “3-F mice”
1)

1)

1)

1)

2)

1)

〇 Kaichi Kasai , Yukihiro Furusawa , Yuki Tada , Naoya Igarashi , Koichi Tsuneyama , Yoshinori Nagai
1)

2)

Department of Pharmaceutical Engineering, Faculty of Engineering, Toyama Prefectural University, Department of Pathology and Laboratory
Medicine, Tokushima University Graduate School
WS14-13-O/P

Direct activation of microglia by β-glucosylceramide causes phagoptosis of neurons that aggravates
Gaucher disease
1, 2)
1)
1, 2)
〇 Takashi Shimizu , Charles Schutt , Sho Yamasaki
1)
Department of Molecular Immunology, Research Institute for Microbial Diseases, Osaka University, Osaka, Japan, 2)Laboratory of Molecular
Immunology, Immunology Frontier Research Center, Osaka University, Osaka, Japan

WS14-14-O/P

Novel lipid metabolism prevents inflammation for neural repair after ischemic stroke
1, 2)
2)
3)
2)
〇 Akari Nakamura , Seiichiro Sakai , Makoto Murakami , Takashi Shichita
1)
Graduate School of Medical and Dental Sciences, Tokyo Medical and Dental University, Tokyo, Japan, 2)Stroke Renaissance Project, Tokyo
Metropolitan Institute of Medical Science, Tokyo, Japan, 3)Laboratory of Microenvironmental and Metabolic Health Science, Center for Disease
Biology and Integrative Medicine, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan

WS14-15-O/P

Modeling bleomycin-induced lung injury using primary murine cell-derived lung organoids〇 Bin Wu, Shigeyuki Shichino, Satoshi Ueha, Kouji Matsushima
Division of molecular regulation of inflammatory and immune diseases, Institution of Biomedical Research, Tokyo University of Science

63

WS15

Autoimmune diseases -Systemic-

14:05 ~ 15:20 Room G
Chairpersons: Isao Matsumoto, Masayuki Nishide

Research on the pathogenesis of systemic autoimmune diseases helps us understand the complexity of the immune systemand the triggers that lead to its dysfunction. Molecular-targeted therapies that have emerged from basic research save many
patients across the world. However, there are still many autoimmune diseases whose pathogenesis remains uncovered, andthe next "revolution" is eagerly awaited. This workshop will explore the diverse mechanisms of autoimmune diseases such as
autoimmune arthritis, systemic lupus erythematosus, and Sjogren’s syndrome. We encourage all attendees to participate inactive and open discussion. Each presentation will have 6 min talk + 2 min discussion.

WS15-01-O/P

SLE stratification based on BAFF and IFN-I bioactivity for biologics and implications of BAFF produced byglomeruli in lupus nephritis〇 Eri Itotagawa, Takehiro Hirayama, Tatsunori Jo, Kohei Tsujimoto, Yasuhiro Kato, Hyota Takamatsu,
Atsushi Kumanogoh
Department of Respiratory Medicine and Clinical Immunology, Graduate School of Medicine, Osaka University, Japan

WS15-02-O/P

Transforming growth factor-β3 in the differentiation and function of T peripheral helper cells and its
relationship to disease activity in patients with systemic lupus erythematosus〇 Yu Shan
The First Department of Internal Medicine, School of Medicine, University of Occupational and Environmental Health, Japan, Kitakyushu, Japan

WS15-03-O/P

DOCK8-expressing T follicular helper cells newly generated beyond self-organized criticality cause
systemic lupus erythematosus (SLE)
1, 2, 3)
, Ken Tsumiyama1, 2, 3), Yumi Miyazaki1, 2), Kenichi Uto2), Keiichi Sakurai1, 3), Takahiko Horiuchi1),〇 Shunichi Shiozawa
3, 3)Tsukasa Matsubara , Takashi Yamane4), Yohei Mukai5), Takuji Enya6), Masaaki Miyazawa6), Kazuko Shiozawa7)
1)

Kyushu University Beppu Hospital, Beppu, Japan, 2)Kobe University, Kobe, Japan, 3)Institute for Rheumatic Diseases, Kato-shi, Japan, 4)
Kakogawa Central City Hospital, Kakogawa, Japan, 5)KAN Research Institute, Inc., Kobe, Japan, 6)Department of Immunology, Kindai University,
Osaka-Sayama, Osaka, Japan, 7)Hyogo Prefectural Kakogawa Medical Center, Kakogawa, Japan
WS15-04-O/P

Vorinostat ameliorates the onset and severity of SLE prone mice by inhibiting IFN-I production.
1, 2)
3)
4)
1, 2)
1, 2, 5, 6)〇 Takehiro Hirayama , Daiki Nagira , Hachiro Konaka , Hyota Takamatsu , Atsushi Kumanogoh
1)

Department of Respiratory Medicine and Clinical Immunology, Graduate School of Medicine, Osaka University, 2)Department of
Immunopathology, WPI, Immunology Frontier Research Center (iFReC), Osaka University, 3)Graduate School of Medicine, Osaka University,
4)
Department of internal medicine, Nippon life Hospital, 5)Center for Infectious Disease Education and Research (CiDER), Osaka University,
6)
Integrated Frontier Research for Medical Science Division, Institute for Open and Transdisciplinary Research Initiatives
WS15-05-O/P

Pathogenic neuropsychiatric effect of stress-induced microglial interleukin 12/23 axis in SLE
1, 2, 3)

〇 Yuki Tanaka, Nobuya Abe1, 4), Masato Tarumi1, 4), Rie Hasebe1, 2, 3), Tatsuya Atsumi4), Masaaki Murakami1, 2, 3)

1)

Division of Molecular Psychoimmunology, Institute for Genetic Medicine, Graduate School of Medicine, Hokkaido University, Sapporo, Japan,
National Institutes for Quantum and Radiological Science and Technology, Quantum Immunology , 3)Division of Molecular Neuroimmunoloy,
Department of Homeostatic Regulation, National Institute for Physiological Sciences, National Institutes of Natural Sciences, 4)Department ofRheumatology, Endocrinology and Nephrology, Faculty of Medicine and Graduate School of Medicine, Hokkaido University, Sapporo, Japan2)

WS15-06-O/P

CD153+ CD4+ T cells exacerbate the autoimmune pathology via the interaction with CD30+ cells in salivary
glands in Sjögren's syndrome
1, 2)
1)
1)
2)
2)
3)
〇 Kunihiro Otsuka , Hiroyuki Kondo , Shin-Ichi Tsukumo , Rieko Arakaki , Mami Sato , Hideo Yagita ,2)
1)
Naozumi Ishimaru , Koji Yasutomo
1)
Department of Immunology and Parasitology, Tokushima University Graduate School of Medicine, 2)Department of Oral Molecular Pathology,
Tokushima University Graduate School of Medicine, 3)Department of Immunology, Juntendo University School of Medicine

WS15-07-O/P

Role of Mucin 19 in Pathogenesis of a Mouse Model for Sjögren's Syndrome〇 Yuki Kawahito, Kai Tamura, Mami Sato, Kunihiro Otsuka, Takaaki Tsunematsu, Naozumi Ishimaru
Department of Oral Molecular Pathology, Tokushima University School of Dentistry, Tokushima, Japan64

WS15-08-O/P

Synovial phenotyping in Japanese RA patients using ultrasound-guided needle biopsy
1)

1)

2)

1)

2)

2)

〇 Risa Yoshihara , Haruka Tsuchiya , Yasunori Omata , Haruka Takahashi , Akihiro Uchio , Yuji Maenohara ,Takumi Matsumoto2), Hiroaki Harada1), Hirofumi Shoda1), Sakae Tanaka2), Tomohisa Okamura3), Keishi Fujio1)
1)
Department of Allergy and Rheumatology, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan, 2)Department of Orthopaedic
Surgery, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan, 3)Department of Functional Genomics and Immunological
Diseases, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan

WS15-09-O/P

Differential TCR repertoire for joint self-antigens determines the functional balance between theregulatory T and arthritogenic T cells in T cell-mediated autoimmune arthritis
1, 2)
1)
1)
1)
2)
1)
〇 Yusuke Takeuchi , Daiya Ohara , Hitomi Watanabe , Gen Kondoh , Akio Morinobu , Keiji Hirota
1)

Laboratory of Integrative Biological Science, Institute for Life and Medical Sciences, Kyoto University, Kyoto, Japan, 2)Department ofRheumatology and Clinical Immunology, Graduate School of Medicine, Kyoto University, Kyoto, Japan

WS16

Tolerance and Immune suppression-1

14:05 ~ 15:20 Room H
Chairpersons: Taku Okazaki, Noriko Komatsu

The generation and activation of self-reactive lymphocytes as well as excess inflammatory responses are tightly restricted bymultiple mechanisms to maintain immune tolerance. Due to the recent success of cancer immunotherapy targeting inhibitory
co-receptors, immune tolerance is rediscovered as a promising target of immunotherapy for various diseases such as cancer,
autoimmune diseases, transplant rejection, and fulminant infection. In this session, we focus on regulatory T and B cells anddiscuss the mechanisms for their differentiation, expansion, maintenance, and activation. Each speaker is allotted 5 min forpresentation and 2 min for Q&A. We welcome your participation and active discussion.

WS16-01-O/P

The Foxp3A384T mutation impairs TCR-induced proliferation of effector regulatory T cells by interfering with
c-Myc induction〇 Suzu Kawagoe, Maori Oda, Ryuichi Murakami, Shohei Hori
Laboratory of Immunology and Microbiology, Graduate School of Pharmaceutical Sciences, The University of Tokyo

WS16-02-O/P

The exon 5 of Ikzf1 is required for Foxp3-dependent gene suppression to maintain the homeostasis ofregulatory T cells〇 Kenji Ichiyama, Shimon Sakaguchi
Immunology Frontier Research Center (IFReC), Osaka University, Japan

WS16-04-O/P

Antigen-specific stimulation induced peripherally derived Treg cells which establish Treg-specificepigenome and orchestrate oral tolerance
1)
1, 2)
1)
1)
1, 2)
〇 Masaya Arai , Ryoji Kawakami , Norihisa Mikami , Yamami Nakamura , Shimon Sakaguchi
1)
Department of Experimental Immunology, Immunology Frontier Research Center (IFReC), Osaka University, Osaka, Japan, 2)Department ofExperimental Immunology, Institute for Life and Medical Sciences, Kyoto university, Kyoto, Japan

WS16-05-O/P

Tonic TCR and IL-1b signaling mediate momentary and durable phenotypic alterations in naive CD4+ T
cells〇 Takashi Sekiya
Department of Immune Regulation, National Center for Global Health and Medicine, Ichikawa, Chiba, Japan

WS16-06-O/P

Identification of a novel intestinal dendritic cell subset drives Rorgt+ Treg differentiation〇 Chengcheng Zou, Ichiro Taniuchi
Laboratory for Transcriptional Regulation, RIKEN Center for Integrative Medical Sciences

WS16-07-O/P

Development of the tolerogenic nanoparticle to induce antigen-specific regulatory T cells
1)

2)

1)

2)

2)

1)

〇 Hiroki Toriumi , Li Shunyi , Daisuke Takahashi , Takanatsu Hosokawa , Liu Yiwei , Yusuke Kinashi ,Seiga Komiyama1), Takeshi Mori2), Koji Hase1)
1)

Division of Biochemistry, Graduate School of Pharmaceutical Science, Keio University, Tokyo, Japan, 2)Department of Applied Chemistry,
Faculty of Engineering, Kyushu University, Fukuoka, Japan65

WS16-08-O/P

Benign and harmful autoimmunity by manipulating the binding stability of self-peptides that influence thekinetics of tissue antigen-specific effector regulatory T cells
1, 2)
3)
4)
5)
6)
〇 Youwei Lin , Shun Sakuraba , Chandirasegaran Massilamany , Jayagopala Reddy , Yoshimasa Tanaka ,7)
1)
Sachiko Miyake , Takashi Yamamura
1)

Department of Immunology, National Institute of Neuroscience, National Center of Neurology and Psychiatry, Tokyo, JAPAN, 2)Departmentof Neurology, National Center Hospital, National Center of Neurology and Psychiatry, Japan, 3)National Institutes for Quantum Scienceand Technology, Institute for Quantum Life Science, Kyoto, Japan, 4)Immuno-oncology CRISPR Therapeutics, Cambridge, USA, 5)Schoolof Veterinary Medicine and Biomedical Sciences, University of Nebraska-Lincoln, Lincoln, USA, 6)Nagasaki University Graduate School of
Biomedical Science, Nagasaki, Japan, 7)Department of Immunology, Juntendo University School of Medicine, Tokyo, Japan
WS16-09-O/P

TRIM28 mediated Treg function underlies suppressive tumor immune environment〇 Hodaka Hayabuchi, Shunsuke Chikuma
Dept of Microbiology and Immunology, School of Medicine, Keio University, Tokyo, Japan

WS16-12-O/P

The effect of Oxytocin on ischemic resistance in recurrence of stroke〇 Ako Matsui, Yoshihiro Harada, Minako Ito
Division of Allergy and Immunology, Medical Institute of Bioregulation, Kyushu University, Fukuoka, Japan

WS16-15-O/P

An anti-CD22 antibody that expands regulatory B cells inhibits development of type 1 diabetes andallograft rejection in mouse models
1)

2)

2)

3)

1)

〇 Wang Long , Shinji Kunitake , Ayaka Endo , Koji Atarashi , Takeshi Tsubata
1)

Pathology Department, Nihon University School of Dentistry, Immunology Department of Tokyo Medical and Dental University, 3)Departmentof Microbiology and Immunology, School of Medicine, Keio University

WS17

2)

Cytokines and Chemokines-1

14:05 ~ 15:20 Room I
Chairpersons: Takayuki Yoshimoto, Yuriko Tanaka

Cytokines and chemokines are key molecules that play critical roles in a variety of biological and immunological aspects
regarding the regulation of not only cell growth, differentiation and trafficking, but also various innate and adaptive immune
responses. Dysregulation of their expression and signal transduction pathways often causes the development of various
diseases including inflammatory, allergic and autoimmune diseases, as well as infectious and malignant neoplastic diseases.
Therefore, the clarification of mechanisms to regulate their expression and signal transduction pathways leads to the elucidationof pathogenesis of these diseases and the development of therapeutic strategy against them. In this session, we will mainly
focus on novel molecules and functions involved in the regulation of signal transduction pathways, cell trafficking, and innate
immune responses.

WS17-01-O/P

DUSP3 regulates the STAT3-mediated signaling pathways
1)

2)

3)

〇 Yuichi Sekine , Kenji Oritani , Tadashi Matsuda
1)

Kyoto Pharmaceutical University, International University of Health and Welfare , 3)Hokkaido University

WS17-03-O/P

2)

The role of TRAF5 in TLR2 expressed by B- and T-lymphocytes and macrophages
1)

1)

1)

1)

1)

2)

1)

〇 Mitsuki Azuma , Hiroaki Saito , Koyo Iwatani , Wakana Imai , Masashi Morita , Naoto Ishii , Takanori So
1)

Laboratory of Molecular Cell Biology, Graduate School of Medicine and Pharmaceutical Sciences, University of Toyama, Toyama, Japan,
Department of Microbiology and Immunology, Tohoku University Graduate School of Medicine, Sendai, Japan2)

WS17-05-O/P

Anti-inflammatory effects of novel NF-κB inhibitory compounds in two inflammatory animal models
1)

1)

1)

2)

2)

2)

〇 Hiroyuki Baba , Tadashi Hosoya , Yuma Kondo , Ryosuke Ishida , Saki Hatsuzawa , Hiroyuki Kagechika ,Shinsuke Yasuda1)
1)

Department of Rheumatology, Graduate School of Medical and Dental Sciences, Tokyo Medical and Dental University (TMDU), Tokyo, Japan,
Institute of Biomaterials and Bioengineering, Tokyo Medical and Dental University (TMDU), Tokyo, Japan2)

66

WS17-06-O/P

Mechanisms of pathogenesis induced by autoimmune disease-associated gene C8orf13
1, 2)
1, 3)
2)
3)
1)
〇 Shintaro Hojyo , Shuhei Shimoyama , Yuki Tanaka , Tatsuya Atsumi , Daisuke Kamimura ,1, 2, 4)Masaaki Murakami
1)
Molecular Psychoimmunology, Institute for Genetic Medicine, Hokkaido University, Sapporo, Japan, 2)Group of Quantum Immunology,
Institute for Quantum Life Science, National Institute for Quantum and Radiological Science and Technology, Inage, Japan, 3)Department ofRheumatology, Endocrinology and Nephrology, Faculty of Medicine and Graduate School of Medicine, Hokkaido University, Sapporo, Japan,
4)
Division of Molecular Neuroimmunology, National Institute for Physiological Sciences, National Institute of Natural Sciences, Okazaki, Japan

WS17-08-O/P

Innate immune responses triggered by CpG DNA-CXCL14 complex is mediated by Immunogloblinsuperfamily proteins
1, 2)
2)
1, 2, 3)〇 Risa Saito , Kosuke Tanegashima , Takahiko Hara
1)

Grad. Sch. of Tokyo Medical and Dental Univ., 2)Stem Cell Project, Tokyo Metropol. Inst. Med. Sci., 3)Grad. Sch. Tokyo Metropol. Univ.

WS17-09-O/P

Rap1 facilitates cell polarization via RhoA signaling in T cells
1)

2)

1)

1)

3)

1)

〇 Yoshihiro Ueda , Koichiro Higasa , Yuji Kamioka , Naoyuki Kondo , Shunsuke Horitani , Yoshiki Ikeda ,Takataro Fukuhara3), Yoshinori Fukui4), Tatsuo Kinashi1)
1)
The Department of Molecular Genetics, Institute of Biomedical Science, Kansai Medical University, 2)The Department of Genome Analysis,
Institute of Biomedical Science, Kansai Medical University, 3)Division of Gastroenterology and Hepatology, the Third Department of Internal
Medicine, Kansai Medical University, 4)Department of Immunobiology and Neuroscience, Medical Institute of Bioregulation, Kyushu University

WS17-10-O/P

Crosstalk between the β2-adrenergic receptor and chemokine receptors in lymphocyte recirculation
through lymph nodes
1, 2)
1, 2, 3)
〇 Akiko Nakai , Kazuhiro Suzuki
1)
Laboratory of Immune Response Dynamics, WPI Immunology Frontier Research Center, Osaka University, Osaka, Japan., 2)Department of
Immune Response Dynamics, Research Institute for Microbial Diseases, Osaka University, Osaka, Japan., 3)Center for Infectious Disease
Education and Research, Osaka University

WS17-11-O/P

Ligand-independent function of β2-adrenergic receptor affects IgE-mediated Ca2+-influx in mast cells
1, 2)
1, 2)
1)
1)
2)
1, 2)
〇 Kei Nagao , Yuki Fujita , Hitoshi Urakami , Atsunori Kamiya , Sachiko Miyake , Soichiro Yoshikawa
1)

Department of Cellular Physiology, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, 2)Department of
Immunology, Juntendo University School of Medicine
WS17-12-O/P

Extracellular DJ-1 has a essential role in the induction of sterile inflammation after ischemic stroke
1, 2)
2)
2)
〇 Koutarou Nakamura , Ryuki Koyama , Takashi Shichita
1)

Graduate School of Frontier Sciences, The University of Tokyo, Tokyo, JAPAN, 2)Stroke Renaissance Project, Tokyo Metropolitan Institute ofMedical Science, Tokyo, Japan

WS17-13-O/P

Conditioned medium of immortalized stem cells from human exfoliated deciduous tooth exhibit protective
effect on the peripheral neuropathy of experimental autoimmune neuritis
1)

2)

3)

4)

5)

6)

〇 Eri Sakamoto , Hideaki Hasegawa , Aruma Watanabe , Yasuhiro Katahira , Satomi Miyakawa , Izuru Mizoguchi ,Takayuki Yoshimoto7)
1)
Department of Immunoregulation, Institute of Medical Science, Tokyo Medical University, Tokyo, Japan, 2)Department of Immunoregulation,
Institute of Medical Science, Tokyo Medical University, Tokyo, Japan, 3)Department of Immunoregulation, Institute of Medical Science, Tokyo
Medical University, Tokyo, Japan, 4)Department of Immunoregulation, Institute of Medical Science, Tokyo Medical University, Tokyo, Japan,
5)
Department of Immunoregulation, Institute of Medical Science, Tokyo Medical University, Tokyo, Japan, 6)Department of Immunoregulation,
Institute of Medical Science, Tokyo Medical University, Tokyo, Japan, 7)Department of Immunoregulation, Institute of Medical Science, Tokyo
Medical University, Tokyo, Japan

67

WS18

T cell function and diseases-2 (Disease models)

15:30 ~ 16:45 Room B
Chairpersons: Masato Kubo, Motoko Kimura

T cells require proper activation and differentiation processes for host defense against pathogens. Multiple mechanisms,
including TCR signaling, costimulatory and inhibitory molecules, cytokines, and metabolites exert key controls on T cellfunction. A comprehensive understanding of the molecular mechanisms laying the T cell activation and differentiation areimportant subjects for future therapeutic application as well. In this session, we will discuss several topics on T cell signaling
and T cell subsets related to immune-senescence, autoimmune diseases, and anti-tumor immune responses. We hope active
participation and discussion in oral and poster presentations. [Each presentation is expected to finish within 7 minutes followedby 2 minutes of discussion.]

WS18-01-O/P

RIPK1 blocks T cell senescence mediated by RIPK3 and caspase-8〇 Takayuki Imanishi, Takashi Saito
Laboratory for Cell Signaling, RIKEN Center for Integrative Medical Sciences (IMS), Yokohama, Japan

WS18-02-O/P

Role of Bcl6 in DNA methylation-mediated T cell senescence and tumorigenesis
1)

2)〇 Hiroko Nakatsukasa , Akihiko Yoshimura
1)

Laboratory of Microbiology and Immunology, Graduate School of Pharmaceutical Sciences, Chiba University, Chiba, Japan, 2)Department ofMicrobiology and Immunology, Keio University School of Medicine, Tokyo, Japan

WS18-03-O/P

Human GC-Tfh cells differentiate into IL-10+ follicular T cells with regulatory functions
1, 2)
2)
1, 2)
1, 2)
2)
1, 2)
〇 Shusei Fujioka , Yusuke Imoto , Mayu Fujioka , Hiroyuki Yoshitomi , Yasuaki Hiraoka , Hideki Ueno
1)
Department of Immunology, Graduate School of Medicine, Kyoto University, Kyoto, Japan, 2)Institute for the Advanced Study of Human Biology(ASHBi), Kyoto, Japan

WS18-04-O/P

Phenotypic and functional analyses reveal self-driven memory-phenotype CD4+ T lymphocytes as aheterogeneous population distinct from foreign antigen-specific memory cells
1, 2, 3), Thomas Ciucci4, 5), Kwang Soon Kim6), Shunichi Tayama1), Akihisa Kawajiri1), Naoto Ishii1),〇 Takeshi Kawabe
2)
Dragana Jankovic , Jinfang Zhu3), Jonathan Sprent7, 8), Remy Bosselut4), Alan Sher2)
1)
Department of Microbiology and Immunology, Tohoku University Graduate School of Medicine, Sendai, Japan., 2)Immunobiology Section,
Laboratory of Parasitic Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, USA.,
3)
Molecular and Cellular Immunoregulation Section, Laboratory of Immune System Biology, National Institute of Allergy and Infectious Diseases,
National Institutes of Health, Bethesda, MD, USA., 4)Laboratory of Immune Cell Biology, Center for Cancer Research, National Cancer Institute,
National Institutes of Health, Bethesda, MD, USA., 5)David H. Smith Center for Vaccine Biology and Immunology, Department of Microbiology
and Immunology, University of Rochester, Rochester, NY, USA., 6)Department of Integrative Biosciences and Biotechnology, Pohang Universityof Science and Technology, Pohang, Republic of Korea., 7)Immunology Division, Garvan Institute of Medical Research, Darlinghurst, NSW,
Australia., 8)St. Vincent's Clinical School, University of New South Wales, Sydney, NSW, Australia.

WS18-05-O/P

Nuclear receptor RORα regulates bystander activation of memory T cells〇 Kensuke Takada, Zimeng Cai, Hironobu Mita, Mina Kozai, Shangyi Wang, Mutsumi Inaba
Laboratory of Molecular Medicine, Faculty of Veterinary Medicine, Hokkaido University

WS18-06-O/P

Charcterization of self glycolipids presented by CD1d that activate NKT cells
1, 2, 3)
, Noriyuki Tomiyasu4), Yoshihiro Izumi4), Akihiro Imamura5), Eri Ishikawa1, 2), Atsushi Kumanogoh3, 6),〇 Yuki Hosono
Hideharu Ishida5), Takeshi Bamba4), Sho Yamasaki1, 2, 6)
1)

Laboratory of Molecular Immunology, Immunology Frontier Research Center, Osaka University, Suita, Japan, 2)Department of Molecular
Immunology, Research Institute for Microbial Diseases, Osaka University, Suita, Japan, 3)Department of Respiratory Medicine and Clinical
Immunology, Graduate School of Medicine, Osaka University, Suita, Japan, 4)Division of Metabolomics, Medical Institute of Bioregulation,
Kyushu University, Fukuoka, Japan, 5)Department of Applied Bioorganic Chemistry, Gifu University, Gifu, Japan, 6)Center for Infectious Disease
Education and Research, Osaka University, Suita, Japan
WS18-07-O/P

A novel subset of Treg controls the progression of colorectal cancer in humans and mice
〇 Kazushige Obata-Ninomiya, Steven F. Ziegler
Benaroya Research Institute, WA, US

68

WS18-08-O/P

Critical roles of an endoribonuclease N4bp1 in regulating CD8 T cell homeostasis and cancer
immunosurveillance〇 Guohao Liu, Yee Kien Chong, Osamu Takeuchi
Department of Medical Chemistry Graduate School of Medicine, Kyoto University

WS19

Mucosal and Skin Surface Barrier

15:30 ~ 16:45 Room C
Chairpersons: Reiko Shinkura, Yoshiyuki Goto

Mucosal and skin lesions serve as a surface barrier against numerous foreign antigens. The surface barrier is a multilayered structure constructed by epithelial cells, intraepithelial lymphocytes, and innate and adaptive immune cells. These
immunocompetent cells interact cooperatively for the maintenance of mucosal and skin homeostasis. Microbiota that resides
on the skin and mucosal surface are unique environmental factors that modulate the function and physiology of host immuneand epithelial cells. Aberrant crosstalk between microbiota and host immune- and epithelial cells predisposes to the hostinflammatory diseases such as inflammatory bowel diseases. This workshop aims to discuss and exchange recent findingson the molecular and cellular mechanism of mucosal and skin barrier system that is based on the unique crosstalk between
microbes and host immune- and epithelial cells.

WS19-01-O/P

Roles of Disialylated Glycan in the Gut Mucosal Barrier
1, 3)
1, 3)
1, 2)
〇 Mugen Taniguchi , Ryu Okumura , Kiyoshi Takeda
1)
Laboratory of Immune Regulation, Department of Microbiology and Immunology, Graduate School of Medicine, Osaka University, Suita,
Japan., 2)Infectious Diseases Unit, Department of Medical Innovations, New Drug Research Division, Otsuka Pharmaceutical Co., Ltd.,
Tokushima, Japan., 3)WPI Immunology Frontier Research Center, Osaka University, Suita, Japan.

WS19-02-O/P

The protective function of conjunctival goblet cell mucin sialylation
1)
1, 2, 3)
, Saaya Fukase1, 2, 3), Meiko Kimura1, 2, 3), Yasuharu Kume1, 2, 3), Kumi Izawa1),〇 Tomoaki Ando , Moe Matsuzawa
Ayako Kaitani1), Ko Okumura1), Akira Matsuda3), Akira Murakami3), Nobuyuki Ebihara2, 3), Jiro Kitaura1, 4)
1)

Atopy (Allergy) Research Center, Juntendo University Graduate School of Medicine (Tokyo, Japan), 2)Department of Ophthalmology, Juntendo
University Urayasu Hospital (Chiba, Japan), 3)Department of Ophthalmology, Juntendo University Graduate School of Medicine, 4)Department of
Science of Allergy and Inflammation, Juntendo University Graduate School of Medicine (Tokyo, Japan)
WS19-03-O/P

Tuft cell-derived IL-25 induced by cecectomy ameliorates colitis development
1)

1, 2, 3)〇 Shunya Hatai , Yasutaka Motomura, Koji Hosomi4), Jun Kunisawa4), Kazuyo Moro1, 2, 3, 5)

1)

Laboratory for Innate Immune Systems, Department of Immunology and Microbiology, Osaka University Graduate School of Medicine,
Laboratory for Innate Immune Systems, RIKEN Center for Integrative Medical Sciences (IMS), 3)Laboratory for Innate Immune Systems, Osaka
University Immunology Frontier Research Center, 4)Laboratory of Vaccine Materials, Center for Vaccine and Adjuvant Research, and Laboratoryof Gut Environmental System, National Institutes of Biomedical Innovation, Health, and Nutrition (NIBIOHN), 5)Laboratory for Innate Immune
Systems, Department of Microbiology and Immunology, Osaka University Graduate School of Frontier Biosciences2)

WS19-12-O/P

Intracellular metabolic adaptation of intraepithelial CD4+CD8aa+ T lymphocytes
1)

2)

3)

1)

1)

〇 Yosuke Harada , Tomohisa Sujino , Kentaro Miyamoto , Ena Nomura , Takanori Kanai
1)

2)

Department of Gastroenterology and Hepatology, School of Medicine, Keio University, Tokyo, Japan, Center for Diagnostic and Therapeutic
Endoscopy, Keio University Hospital, Tokyo, Japan, 3)Miyarisan Pharm. Co. Ltd. Tokyo, Japan
WS19-13-O/P

Epithelial HVEM maintains intraepithelial T cell survival and contributes to host protection
1, 2)
1)
1)
1)
1)
〇 Daisuke Takahashi , Goo-Young Seo , Qingyang Wang , Zbigniew Mikulski , Mitchell Kronenberg
1)

La Jolla Institute for Immunology, 2)Keio University Faculty of Phamacy

WS19-14-O/P

Basolateral sorting of CD166 in intestinal epithelial cells by clathrin adaptor protein AP-1B is required forinteraction with intraepithelial lymphocytes
1)

2)

1)

1)

1)

1)

〇 Ryohtaroh Matsumoto , Kosuke Ogata , Daisuke Takahashi , Yusuke Kinashi , Takahiro Yamada , Aiko Saeki ,Hiroshi Ohno3), Yasushi Ishihama2), Shunsuke Kimura1), Koji Hase1)
1)

Division of Biochemistry, Graduate School of Pharmaceutical Science, Keio University, 2)Department of Molecular & Cellular BioAnalysis,
Graduate School of Pharmaceutical Sciences, Kyoto University, 3)Laboratory of Intestinal Ecosystem, RIKEN Center for Integrative Medical
Science69

WS19-18-O/P

Intestinal barrier dysfunction by intestine-specific AP-1B deficiency causes IgA nephropathy-like
symptoms
1)

1)

2)

1)

1)

〇 Yusuke Kinashi , Daisuke Takahashi , Hiroshi Ohno , Shunsuke Kimura , Koji Hase
1)

2)

Division of Biochemistry, Graduate School of Pharmaceutical Science, Keio University, Tokyo, Japan, Laboratory for Intestinal Ecosystem,
RIKEN Center for Integrative Medical Sciences, Yokohama, Japan
WS19-19-O/P

Selective IgA deficiency induces spontaneous inflammation in the ileum
1)

1)

1)

2)

1)

3)

〇 Takashi Nagaishi , Daiki Yamada , Tadahiko Inoue , Richard S. Blumberg , Ryuichi Okamoto , Takahiro Adachi
1)

2)

Department of Gastroenterology, Graduate School of Medical Science, Tokyo Medical and Dental University, Tokyo, Japan., Gastroenterology
Division, Brigham and Women’s Hospital, Harvard Medical School, Boston, MA, USA., 3)Department of Precision Health, Medical ResearchInstitute, Tokyo Medical and Dental University, Tokyo, Japan.
WS19-20-O/P

Detection of S-IgA antibodies in plasma of neonates and identification of the source〇 Kaori Ito, Kohta Saukurai, Mutsumi Furukawa, Tomonori Nochi
International Education and Research Center for Food and Agricultural Immunology, Graduate School of Agricultural Science, Tohoku University,
Miyagi, Japan

WS20


Dendritic cells and macrophages-2: Myeloid cell linage and their differentiation
15:30 ~ 16:45 Room D
Chairpersons: Yasutaka Okabe, Masako Kohyama

Dendritic cells (DCs), macrophages, and monocytes, collectively called myeloid cells, are found in almost all tissues in the
body. It has emerged that myeloid cells comprise a variety of subsets, and they are highly heterogeneous populations in termsof their phenotypes and functions. In this session, we will discuss recent progress in our understanding of the differentiationand polarization of myeloid cells as well as the identification of novel subsets.

WS20-02-O/P

Transcriptomic and functional analyses uncover an immature subpopulation of basophils in the bonemarrow and FoxO1 as a transcription factor involved in the regulation of basophil responsiveness
1)

1)

1)

2)

1)

〇 Junya Ito , Kensuke Miyake , Kazufusa Takahashi , Shigeyuki Shichino , Hajime Karasuyama
1)

Inflammation, Infection and Immunity Laboratory, Advanced Research Institute, Tokyo Medical and Dental University, Tokyo, Japan, 2)Divisionof Molecular Regulation of Inflammatory and Immune Diseases, Research Institute of Biomedical Sciences, Tokyo University of Science, Noda,
Japan

WS20-04-O/P

Activation of retinoid X receptor promotes differentiation of monocytes into CX3CR1hi macrophages in the
colon
1)

1)

2)

3)

4)

5)

1)

〇 Wakana Ohashi , Masayoshi Onuki , Eiji Umemoto , Masaru Ishii , Kiyoshi Takeda , Hiroki Kakuta , Koji Hase
1)

2)

Division of Biochemistry, Faculty of Pharmacy, Keio University, Tokyo, Japan, Laboratory of Microbiology and Immunology, School of
Pharmaceutical Sciences, University of Shizuoka, Shizuoka, Japan, 3)Department of Immunology and Cell Biology, Graduate School of Medicine,
Osaka University, Osaka, Japan, 4)Department of Microbiology and Immunology, Graduate School of Medicine, Osaka University, Osaka, Japan,
5)
Division of Pharmaceutical Sciences, Graduate School of Medicine Dentistry and Pharmaceutical Sciences, Okayama University, Okayama
Japan
WS20-05-O/P

Identification of differentiation pathway for neutrophil-like monocytes during emergency hematopoiesis
1)
1)
2)
3, 4)
5)
5)
〇 Naoki Ikeda , Ayaka Iwata , Takashi Kamatani , Tatsuhiko Tsunoda , Yoshihiro Hayashi , Hironori Harada ,Yuka Harada6), Masato Tanaka1), Kenichi Asano1)
1)

Lab. of Immune Regulation, Tokyo University of Pharmacy and Life Sciences, 2)M&D Data Science Center, Tokyo Medical and Dental University,
Graduate School of Science, The University of Tokyo, 4)RIKEN Center for Integrative Medical Sciences, 5)Lab. of Oncology, Tokyo University of
Pharmacy and Life Sciences, 6)Department of Clinical Laboratory, Komagome Hospital3)

WS20-09-O/P

CSF1-producing cells in the intestine contributes to the maintenance of macrophages〇 Daichi Nonaka, Eriko Sumiya, Shinichiro Sawa
Medical institute of bioregulation Kyushu university

WS20-10-O/P

Molecular mechanisms of short-chain fatty acids-mediated transactivation of integrin genes in dendriticcells〇 Weiting Zhao, Kazuki Nagata, Naoto Ito, Masakazu Hachisu, Chiharu Nishiyama
Department of Biological Science and Technology, Tokyo University of Science, Tokyo, Japan70

WS20-15-O/P

Migratory CD301b+ cDC2 cells instruct the fate of effector CD4 T cells through cognate interactions〇 Naoya Tatsumi, Yosuke Kumamoto
Rutgers New Jersey Medical School, Newark, NJ, USA

WS20-19-O/P

The aryl hydrocarbon receptor instructs the immunomodulatory profile of a subset of Clec4a4+ eosinophils
unique to the small intestine
1, 2)
2)
2)
2)
2)
〇 Jun Kasamatsu , Wei-Le Wang , Susan Gilfillan , Marina Cella , Marco Colonna
1)
Department of Intelligent Network for Infection Control Tohoku University Graduate School of Medicine, 2)Department of Pathology and
Immunology, Washington University School of Medicine in Saint Louis

WS20-20-O/P

Identification of a novel macrophage subset involved in pulmonary fibrosis by intravital imaging
techniques〇 Akio Suzuki, Junichi Kikuta, Masaru Ishii
Department of Immunology and Cell Biology, Graduate School of Medicine and Frontier Biosciences, Osaka University, Osaka, Japan

WS21

Molecular and cellular diversity of allergic diseases (II)

15:30 ~ 16:45 Room E
Chairpersons: Akira Shibuya, Haruka Miki

Allergic responses involve a variety of players such as hematopoietic and non-hematopoietic cells, cytokines, and IgE
antibodies. To understand and control allergic diseases, it is essentially required to clarify how these players interact each other.
This session focuses on type 2 immune cells and cytokines Th2 and ILC2 and IL-4 and IL-13, respectively. In addition, we also
discuss on mast cells and basophils, effector cells for allergic responses. We will discuss on how these players are involvedin the development of allergic airway inflammation, allergic rhinitis, anaphylaxis, food allergy, atopic dermatitis, and contact
hypersensitivity, and try to explore novel therapeutic approaches to intractable allergic diseases.

WS21-01-O/P

Tigit mediates activation-induced cell death of ILC2s
1, 2)
1)
1)
1)
3)
〇 Toshiki Yamada , Akane Fuchimukai , Megumi Tatematsu , Shunsuke Takasuga , Hideyuki Yoshida ,
4)
4, 5)
1)
Kazuko Shibuya , Akira Shibuya , Takashi Ebihara
1)

Department of Medical Biology, Akita University Graduate School of Medicine, 2)Department of Otorhinolaryngology-Head and Neck Surgery,
Akita University Graduate School of Medicine, 3)YCI Laboratory for Immunological Transcriptomics, RIKEN Center for Integrative Medical
Sciences, 4)Department of Immunology, Faculty of Medicine, University of Tsukuba, 5)Life Science Center for Survival Dynamics, Tsukuba
Advanced Research Alliance (TARA), University of Tsukuba
WS21-02-O/P

Lung local IL-7 affect the maintenance, distribution, and activation of ILC2 in allergic airway
inflammations〇 Daichi Takami, Shinya Abe, Akihiro Shimba, Koichi Ikuta
Institute for Life and Medical Sciences, Kyoto University, Kyoto, Japan

WS21-03-O/P

The role of local Th2 activation in the development of allergic rhinitis〇 Saya Tezuka, Kazufumi Matsushita, Etsushi Kuroda
Department of Immunology, Hyogo Medical University, Hyogo, Japan

WS21-04-O/P

The role of IL-13 on dendritic cells is critical for type 2 immune responses〇 Yasuyo Harada, Masato Kubo
Research Institute for Biomedical Sciences, Tokyo University of Science, Chiba, Japan

WS21-05-O/P

The anti-allergic effects of short chain fatty acids and niacin targeting IgE-dependent mast cell activation
via modulating GPCR-signaling of EP3 and GPR109A, and by epigenetic regulation
1)
1)
1)
1)
1)
2, 3)
1)
〇 Daisuke Ando , Kazuki Nagata , Tsubasa Ashikari , Kandai Ito , Naoto Ito , Makoto Arita , Chiharu Nishiyama
1)
Department of Biological Science and Technology, Tokyo University of Science, Tokyo, Japan, 2)Graduate School of Pharmaceutical Sciences,
Keio University, Tokyo, Japan, 3)RIKEN Center for Integrative Medical Science, Kanagawa, Japan71

WS21-06-O/P

Development of a murine model for oral allergy syndrome to identify IgE cross-reactive pollen and foodallergens
1, 2)
1, 3)
1)
1)
1)
1)
〇 Risa Yamamoto , Anna Kamei , Kumi Izawa , Tomoaki Ando , Ayako Kaitani , Akie Maehara ,
1, 4)
1, 3)
1, 3)
1)
1)
Yasuharu Kume , Hexing Wang , Koji Tokushige , Nobuhiro Nakano , Ko Okumura , Jiro Kitaura1)
1)

Atopy (Allergy) Research Center, Juntendo University Graduate School of Medicine, Tokyo, Japan, 2)Juntendo University School of Medicine (5thyear medical student), Tokyo, Japan, 3)Department of Science of Allergy and Inflammation, Juntendo University Graduate School of Medicine,Tokyo, Japan, 4)Department of Ophthalmology, Juntendo University Urayasu Hospital, Chiba, Japan
WS21-07-O/P

The kappa opioid alleviates the OVA-induced food allergy via the brain-gut axis and immunomodulation
1)

2)

1)

〇 Kazuki Nagata , Hiroshi Nagase , Chiharu Nishiyama
1)

Department of Biological Science and Technology, Tokyo University of Science, Tokyo, Japan, 2)University of Tsukuba, IIIS

WS21-08-O/P

Difamilast, a selective phosphodiesterase 4 inhibitor, suppresses IL-4 production by basophils andameliorates atopic dermatitis in a murine model
1, 2)
1)
1)
1, 3)
1)
〇 Kazufusa Takahashi , Kensuke Miyake , Junya Ito , Hinano Shimamura , Hajime Karasuyama
1)

Inflammation, Infection, Immunity Laboratory, Advanced Research Institute, Tokyo Medical and Dental University (TMDU), Tokyo, Japan,
Depertment of Human Pathology, Graduate School of Medical and Dental Sciences, Tokyo Medical and Dental University (TMDU), Tokyo,
Japan, 3)Depertment of Medical Science, Graduate School of Medical Sciences, Kitasato University, Kanagawa, Japan2)

WS21-09-O/P

miR-451a suppresses delayed-type hypersensitivity by regulating Th17 differentiation
1, 2)
1)
1)
〇 Takanobu Yoshida , Ken Takashima , Hiroyuki Oshiumi
1)Department of Immunology, Graduate School of Medical Sciences, Faculty of Life Sciences, Kumamoto University, 2)Department of Pediatrics,
Graduate School of Medical Sciences, Kumamoto University

WS22

Hematopoiesis and Immune Environment

15:30 ~ 16:45 Room F
Chairpersons: Tomokatsu Ikawa, Ari Itoh-Nakadai

All immune cells are derived from hematopoietic stem cells that are capable of self-renewal and differentiation into multilineage
progenitors. Progenitors further proliferate and differentiate into diverse functional mature cells in the bone marrow or in thethymus for generating T cells. Each lymphoid organ has its specific microenvironment that orchestrates the development
and homeostasis of the immune cells. Under inflammatory conditions, steady-state hematopoiesis switches to emergency
myelopoiesis to give rise to the effector cell types to protect from infection and tissue damage. In this session, we will focus on
the cellular and molecular mechanisms during immune cell development. We will also discuss hematopoietic dysregulation andmalignancies.

WS22-01-O/P

Critical role of N6-methyladenosine modification deposited by METTL16 in hematopoiesis
1)

2)

1)

〇 Masanori Yoshinaga , Michael C Bassik , Osamu Takeuchi
1)

Department of Medical Chemistry, Graduate School of Medicine, Kyoto University, 2)Department of Genetics, Stanford University

WS22-02-O/P

Tracing the evolutionary history of T cells back to invertebrates
1)

1)

2)

1)

〇 Yosuke Nagahata , Ryota Kaitani , Yutaka Satou , Hiroshi Kawamoto
1)

2)

Laboratory of Immunology, Institute for Life and Medical Sciences, Kyoto University, Department of Zoology, Graduate School of Science,
Kyoto University
WS22-03-O/P

Akkermansia muciniphila induces chronic extramedullary hematopoiesis through innate immune signals
1, 2)
1, 3)
1, 3)
1)
4)
4, 5, 6)
, Yuhua Li2, 7),〇 Yuxin Wang , Tatsuya Morishima , Maiko Sezaki , Ryo Sato , Gaku Nakato , Shinji Fukuda
1, 8)
Hitoshi Takizawa
1)
Laboratory of Stem Cell Stress, International Research Center for Medical Sciences (IRCMS), Kumamoto University, Kumamoto, 2)Zhujiang
Hospital, Southern Medical University, Guangzhou, China, 3)Laboratory of Hematopoietic Stem Cell Engineering, IRCMS, Kumamoto University,
Kumamoto, 4)Gut Environmental Design Group, Kanagawa Institute of Industrial Science and Technology , Kanagawa, 5)Institute for Advanced
Biosciences (IAB), Keio University, Tokyo, 6)Transborder Medical Research Center, University of Tsukuba, Ibaraki, 7)Bioland Laboratory(Guangzhou Regenerative Medicine and Health Guangdong Laboratory), Guangzhou, Guangdong, China, 8)Center for Metabolic Regulation of
Healthy Aging (CMHA), Kumamoto University, Kumamoto72

WS22-04-O/P

Single cell genomics revealed critical molecules affecting cell fate of human stem/progenitor cells
1, 2)
1)
1)
1)
3)
〇 Makoto Iwasaki , Joachim Luginguhehl , Yoriko Saito , Ari Itoh-Nakadai , Leonard Shultz ,2)
1)
1)
Akifumi Takaori-Kondo , Jay Shin , Fumihiko Ishikawa
1)

RIKEN Center for Integrative Medical Sciences, Yokohama, Japan, 2)Department of Hematology and Oncology, Kyoto University, Kyoto, Japan,
The Jackson Laboratory, Bar Harbor, ME

3)

WS22-05-O/P

Novel insights into heterogeneity of embryo-derived B cells divided two distinct subsets in adulthood
1)
1, 2)
1)
1)
3)
2)
〇 Keiko Fujisaki , Nanako Okamoto , Aika Otaki , Yuhei Mizunoe , Shogo Okazaki , Chiharu Nishiyama ,Ryo Goitsuka1)
1)

Division of Cell Fate Regulation, Research Institute for Biomedical Sciences, Tokyo University of Science, 2)Laboratory of Molecular Biology
and Immunology, Department of Biological Science and Technology, Tokyo University of Science, 3)Department of Microbiology, Nihon
University School of DentistryWS22-06-O/P

The function of Polycomb group proteins during B cell development〇 Mayumi Hirakawa, Tomokatsu Ikawa
Tokyo University of Science Research Institute for Biomedical Sciences Division of Immunology and allergy

WS22-07-O/P

BCR-ABL-induced senescence-associated autophagy bring about maintenance of CML stemness
1)

1)

2)

2)

〇 Yamato Tanabe , Makoto Kurachi , Tomohisa Baba , Naofumi Mukaida
1)

2)

Department of Molecular Genetics, Kanazawa University, Cancer Research Institute, Kanazawa University

WS22-08-O/P

Runx1 and Runx2 inhibit fibrotic conversion of cellular niches for hematopoietic stem cells〇 Yoshiki Omatsu, Takashi Nagasawa
Graduate School of Frontier Biosciences, Osaka University

WS22-09-O/P

Distinct binding properties of integrin adaptors talin1 and kindlin-3 to LFA1 and α4 integrins modulateadhesive responses in static and shear-flow conditions〇 Naoyuki Kondo, Yuji Kamioka, Yoshiki Ikeda, Yoshihiro Ueda, Tatsuo Kinashi
Kansai Medical University

WS22-10-O/P

The role of isolated CD35+ follicular dendritic cells in the differentiation from B cells to IgA+ GL7+ cells〇 Mari Hikosaka-Kuniishi, Toshiyuki Yamane, Doris Narki Tetteh, Hidetoshi Yamazaki
Department of Stem Cell and Developmental Biology, Mie University Graduate School of Medicine

WS23

Human Immunology (Immunointervention)

15:30 ~ 16:45 Room G
Chairpersons: Keishi Fujio, Ai Tachikawa

Mouse models have made a highly important contribution to the understanding of immune system. On the other hand, it
has become clear that human immunity has some differences from mouse immunity, and there is a growing need to better
understand human immunity itself. Recent technological advances, such as next-generation sequencing and flowcytometry, areadvancing the analysis of human immune system. Combining this understanding of human immunity with findings from mousemodels will enable a deeper understanding of the immune system. In this session, the latest findings from genome analysis,
humanized mice, mouse models, and human cell analysis that lead to a better understanding of human immunity will bepresented. We hope that these presentations will lead to a better understanding of human immunity and elucidation of disease
pathology.

WS23-01-O/P

An atlas of transcribed enhancers across helper T cell diversity for decoding human diseases
1, 2)
3)
1)
4, 5, 6)
, Kazuhiko Yamamoto3),〇 Akiko Oguchi , Akari Suzuki , Shuichiro Komatsu , Chikashi Terao
1, 7, 8, 9)
Yasuhiro Murakawa
1)

RIKEN-IFOM Joint Laboratory for Cancer Genomics, RIKEN Center for Integrative Medical Sciences, Yokohama, Japan, 2)Department ofNephrology, Graduate School of Medicine, Kyoto University, Kyoto, Japan, 3)Laboratory for Autoimmune Diseases, RIKEN Center for Integrative
Medical Sciences, Yokohama, Japan, 4)Laboratory for Statistical and Translational Genetics, RIKEN Center for Integrative Medical Sciences,
Yokohama, Japan, 5)Clinical Research Center, Shizuoka General Hospital, Shizuoka, Japan, 6)Department of Applied Genetics, School of
Pharmaceutical Sciences, University of Shizuoka, Shizuoka, Japan, 7)IFOM - the FIRC Institute of Molecular Oncology, Milan, Italy., 8)Institutefor the advanced study of human biology, Kyoto University, Kyoto, Japan, 9)Department of Medical Systems Genomics, Graduate School of
Medicine, Kyoto University, Kyoto, Japan73

WS23-02-O/P

Mechanisms of impaired hematopoiesis caused by the IKZF1N159S variant〇 Jingjie Chang, Kazuki Okuyama, Junji Harada, Chengcheng Zou, Ichiro Taniuchi
Integrative Medical Sciences (IMS), RIKEN, Yokohama, Japan

WS23-03-O/P

Actively transcribed regulatory regions drive the genetic risk of rheumatoid arthritis
1)

2)

2)

1)

2)

3)

〇 Hiroaki Hatano , Akari Suzuki , Matteo Guerrini , Michihiro Kono , Masahiro Nakano , Akiko Oguchi ,Chikashi Terao4), Yasuhiro Murakawa3), Kazuhiko Yamamoto2), Kazuyoshi Ishigaki1)
1)

Laboratory for Human Immunogenetics, RIKEN Center for Integrative Medical Sciences, Yokohama, Kanagawa, Japan, 2)Laboratory for
Autoimmune Diseases, RIKEN Center for Integrative Medical Sciences, Yokohama, Kanagawa, Japan, 3)Joint Laboratory for Cancer Genomics,
RIKEN Center for Integrative Medical Sciences RIKEN-IFOM, Yokohama, Kanagawa, Japan, 4)Laboratory for Statistical and Translational
Genetics, RIKEN Center for Integrative Medical Sciences , Yokohama, Kanagawa, Japan
WS23-04-O/P

Establishment of human immune system mice for evaluation of rejection of HLA-depleted cells inregenerative medicine
1)

1)

1)

1)

2)

2)

3)

〇 Charlotte Flahou , Natsumi Higashi , Huaigeng Xu , Akitsu Hotta , Bo Wang , Shin Kaneko , Tatsuya Morishima ,Hitoshi Takizawa3), Koji Eto1, 4), Naoshi Sugimoto1)
1)
Department of Clinical Application, Center for iPS Cell Research and Application (CiRA), Kyoto University, Kyoto, Japan, 2)Department of Cell
Growth and Differentiation, Center for iPS Cell Research and Application (CiRA), Kyoto University, Kyoto, Japan, 3)International Research Center
for Medical Sciences (IRCMS), Kumamoto University, Kumamoto, Japan, 4)Department of Regenerative Medicine, Chiba University Graduate
School of Medicine, Chiba, Japan

WS23-08-O/P

Pathogenic analysis of the idiotypic multicentric Casthleman disease (iMCD)- Aberrant immunoregulatory
disorder revealed by the iMCD model mice which was transplanted with patient’s lymph mode cells 1)

2)

2)

3)

4)

5)

〇 Kazuyuki Yoshizaki , Yoshikane Kikushige , Takuya Harada , Kazuko Uno , Mitunori Kaneko , Hiroaki Niiro ,Kouichi Akashi5)
1)
SANKEN Osaka University, Osaka, Japan, 2)Kyushu University Hospital, Fukuoka, Japan, 3)Louis Pasteur Medical Research center, Kyoto,
Japan, 4)Suita Tokusyukai Hospital, Osaka, Japan, 5)Kyushu University , Fukuoka, Japan

WS23-09-O/P

Fab fragments against human IgE Cε2 inhibit the binding of IgE to its receptors
1)

1)

2)

2)

1)

1)

1)

〇 Hexing Wang , Tomoaki Ando , Toshiaki Maruyama , Cj Okumura , Kumi Izawa , Ayako Kaitani , Yasuharu Kume ,Koji Tokushige1, 3), Nobuhiro Nakano1), Keiko Maeda1), Ko Okumura 1), Jiro Kitaura1, 3)
1)
Atopy (Allergy) Research Center, Juntendo University Graduate School of Medicine (Tokyo, Japan), 2)Abwiz Bio Inc. (CA, USA), 3)Department of
Science of Allergy and Inflammation, Juntendo University Graduate School of Medicine (Tokyo, Japan)

WS23-10-O/P

Innate IgE exacerbates allergic disease via amplification of ILC2 activation
1, 2, 3)

〇 Yasutaka Motomura, Yohei Maeda4), Masaki Hayama4), Kazuyo Moro1, 2, 3)

1)

Laboratory for Innate Immune Systems, Department of Microbiology and Immunology, Graduate School of Medicine, Osaka University,
Osaka, Japan, 2)Laboratory for Innate Immune Systems, Osaka University Immunology Frontier Research Center (IFReC), 3)Laboratory for Innate
Immune Systems, RIKEN IMS, Kanagawa, Japan, 4)Department of Otorhinolaryngology-Head and Neck surgery, Graduate School of Medicine,
Osaka University, Osaka, Japan
WS23-11-O/P

Withdrawn

WS23-13-O/P

Quantitative and qualitative differences in HBc-specific CD8 T cells could impact the level of HBsAg in
Hepatitis B patients
1)
2)
1, 3)
1, 4)
1)
〇 Shokichi Takahama , Sachiyo Yoshio , Hirotomo Murakami , Hirofumi Akita , Takuto Nogimori ,
5)
5)
6)
7)
7)
Shun Kaneko , Masayuki Kurosaki , Yasuhiro Asahina , Ryotaro Sakamori , Tetsuo Takehara , Tatsuya Kanto2),
Takuya Yamamoto1, 4, 8, 9)
1)
Laboratory of Immunosenescence, Center for Vaccine and Adjuvant Research, National Institutes of Biomedical Innovation, Health andNutrition, Osaka, Japan, 2)Department of Liver Diseases, Research Center for Hepatitis and Immunology, National Center for Global Health andMedicine, Tokyo, Japan, 3)Department of Gastroenterological Surgery, Graduate School of Medicine, Osaka University, Osaka, Japan,
4)
Laboratory of Translational Cancer Immunology and Biology, Next-generation Precision Medicine Research Center, Osaka International Cancer
Institute, Osaka, Japan, 5)Department of Gastroenterology and Hepatology, Musashino Red Cross Hospital, Tokyo, Japan, 6)Department of Liver
Disease Control, Tokyo Medical and Dental University, Tokyo, Japan., 7)Department of Gastroenterology and Hepatology, Osaka University
Graduate School of Medicine, Osaka, Japan., 8)The Research Institute for Microbial Diseases, Osaka University, Osaka, Japan., 9)Department of
Virology and Immunology, Graduate School of Medicine, Osaka University, Osaka, Japan.

74

WS24

Tolerance and Immune suppression-2

15:30 ~ 16:45 Room H
Chairpersons: Kazuko Shibuya, Daisuke Sugiura

As described in WS16 Tolerance and immune suppression-1, multiple mechanisms are involved in the establishment and themaintenance of immune tolerance. In this session, we focus on mechanisms other than the active suppression by regulatory
cells, which include thymic negative selection, antigen presentation, co-receptors, and cytokines. Each speaker is allotted 5 minfor presentation and 2 min for Q&A. We welcome your participation and active discussion.

WS24-01-O/P

PD-1 agonism by anti-CD80 inhibits T cell activation and alleviates autoimmunity
1)

1)

1)

1)

2)

1)

〇 Daisuke Sugiura , Il-Mi Okazaki , Takumi Maruhashi , Kenji Shimizu , Naozumi Ishimaru , Taku Okazaki
1)

2)

Laboratory of Molecular Immunology, Institute for Quantitative Biosciences, The University of Tokyo, Tokyo, Japan, Department of Oral
Molecular Pathology, Graduate School of Biomedical Sciences, Tokushima University, Tokushima, Japan

WS24-02-O/P

CD45 modulation augments CD8 T cell energy metabolism and function in aged mice, reverting
resistance to PD-1 blockade cancer immunotherapy
1)

1)

1)

2)

1)

〇 Sara Delghandi , Kenji Chamoto , Yuka Nakajima , Hidetaka Kosako , Tasuku Honjo
1)

Division of Immunology and Genomic Medicine, Center for Cancer Immunotherapy and Immunobiology, Kyoto University Graduate School of
Medicine, 2)Division of Cell Signaling, Fujii Memorial Institute of Medical Sciences, Tokushima University
WS24-05-O/P

A novel allergen-specific anergic T cell therapy induced by the blockade of T cell co-stimulation, Koichiro Uchida3), Ko Okumura1, 3, 4)

1, 2, 3)

1)

〇 Yui Maehara , Kazuyoshi Takeda
1)

Department of Biofunctional Microbiota, Juntendo University, 2)Laboratory of Cell Biology, Research Support Center, Graduate School of
Medicine, Juntendo University, 3)Center for Immune Therapeutics and Diagnosis, Juntendo Advanced Research Institute for Health Science,
Juntendo University, 4)Atopy (Allergy) Research Center, Graduate School of Medicine, Juntendo University
WS24-09-O/P

Identification and binding analysis of novel receptors for HLA-G2〇 Hiroshi Watanabe, Kimiko Kuroki, Katsumi Maenaka
Faculty of Pharmaceutical Science, Hokkaido University, Sapporo, Japan

WS24-10-O/P

Abrogation of self-tolerance by self-antigen complexed with MHC class II molecules
1)

1, 2)

〇 Hui Jin , Hisashi Arase1)

Department of Immunochemistry, Research Institute for Microbial Diseases, Osaka University, Osaka, Japan, 2)Laboratory of Immunochemistry,
WPI Immunology Frontier Research Center, Osaka University, Osaka, Japan
WS24-11-O/P

Induction of Regulatory T Cells by Ubiquitinated MHC II〇 Yuko Kozono, Fan Baicheng, Haruo Kozono
Research Institute for Biomedical Sciences, Tokyo University of Sciences, Noda, Chiba, Japan

WS24-15-O/P

IL-18 Regulates Immune Responses Contributing Placental Development and Fetal Growth
1, 2)
1, 2)
1, 2)
2)
1)
〇 Hajime Ino , Yumi Horii , Yasuyuki Negishi , Shunji Suzuki , Rimpei Morita
1)

Department of Microbiology and Immunology, Nippon Medical School, Tokyo, Japan, 2)Department of Gynecology and Obstetrics, Nippon
Medical School, Tokyo, Japan
WS24-17-O/P

CCR9 inhibition alters tissue distribution of plasmacytoid dendritic cells and leads to hepatic immune
suppression〇 Yuzo Koda, Nobuhiro Nakamoto, Takanori Kanai
Division of Gastroenterology and Hepatology, Department of Internal Medicine, Keio University School of Medicine

WS24-19-O/P

AIRE leaves footprints on chromatin for immunological self-tolerance〇 Kenta Horie, Nobuko Akiyama, Taishin Akiyama
Center for Integrative Medical Sciences, Riken, Yokohama, Japan

WS24-20-O/P

CXCR4 defines transit-amplifying cells of medullary thymic epithelial cells〇 Tatsuya Ishikawa

1, 2), Taishin Akiyama 1, 2), Nobuko Akiyama 1)

1)

RIKEN Center for Integrative Medical Sciences, Yokohama, Japan, 2)Graduate School of Medical Life Science, Yokohama City University,
Yokohama, Japan

75

WS25

Cytokines and Chemokines-2

15:30 ~ 16:45 Room I
Chairpersons: Tomonori Kaifu, Minako Ito

Cytokines and chemokines are key molecules that play critical roles in a variety of biological and immunological aspects
regarding the regulation of not only cell growth, differentiation and trafficking, but also various innate and adaptive immune
responses. Dysregulation of their expression and signal transduction pathways often causes the development of various
diseases including inflammatory, allergic and autoimmune diseases, as well as infectious and malignant neoplastic diseases.
Therefore, the clarification of mechanisms to regulate their expression and signal transduction pathways leads to the elucidationof pathogenesis of these diseases and the development of therapeutic strategy against them. In this session, we will mainly
focus on novel molecules and functions involved in the regulation of adaptive immune responses and development of diseases
using various disease models.

WS25-03-O/P

Lactococcus lactis subsp. Cremoris C60 restores T Cell Population in Small Intestinal Lamina Propria in
Aged Interleukin-18 Deficient Mice1, 2, 3)〇 Toshio Maekawa, Suguru Saito3, 4), Noriko Tsuji1, 2, 3, 5)

1)

Microbiology/Immune Homeostasis, Dept. Pathology and Microbiology, Nihon University, School of Medicine, Tokyo, Japan, 2)iFoodmed.
Inc. Research Inst., Ibaraki, Japan, 3)Cellular and Molecular Engineering, Dept. Life Technology and Science, AIST, 4)Dept. Dentistry, Faculty of
Medicine and Dentistry, University of Alberta, 5)Dept. Food Science, Jumonji University, Saitama, Japan
WS25-04-O/P

The source and function of soluble ST2〇 Pei-Chi Lo , Yasutaka Motomura, Kazuyo Moro1, 2, 3, 4)

1)

1)

1, 2, 3)

2)

Graduate School of Medicine, Osaka University, Osaka University Immunology Frontier Research Center (IFReC),, 3)Graduate School of
Frontier Biosciences, Osaka University, 4)RIKEN Center for Integrative Medical Sciences
WS25-05-O/P

Anti-IgE Ab treatment attenuates OVA-Ag-induced neutrophilic airway inflammation and IL-17 productionin the lungs
1, 2)
3)
2, 4)
3)
2, 4)
〇 Kazuyuki Nakagome , Mitsuru Imamura , Masaaki Kawano , Kimito Kawahata , Rie Takagi ,
5)
2, 4)
1, 2)
Hiroaki Harada , Sho Matsushita , Makoto Nagata
1)
Department of Respiratory Medicine, Saitama Medical University, Saitama, Japan , 2)Allergy Center, Saitama Medical University, Saitama,
Japan, 3)Division of Rheumatology and Allergology, Department of Internal Medicine, St Marianna University School of Medicine, Kanagawa.,
4)
Department of Allergy and Immunology, Saitama Medical University, Saitama, Japan, 5)Department of Allergy and Rheumatology, Graduate
School of Medicine, University of Tokyo, Tokyo, Japan

WS25-06-O/P

Suppression of itch sensation by IL-27
1)

1)

2)

3)

3)

4)

〇 Daiji Sakata , Yusuke Nomoto , Masahiro Yamamoto , Chisa Nakashima , Kenji Kabashima , Hiroki Yoshida ,Takuro Kanekura5), Hiromitsu Hara1)
1)

Laboratory of Immunology, Department of Infection and Immunity, Graduate School of Medical and Dental Sciences, Kagoshima University,
Department of Immunoparasitology, Division of Infectious Disease, Research Institute for Microbial Diseases, Osaka University, 3)Department of
Dermatology, Graduate School of Medicine and Faculty of Medicine, Kyoto University, 4)Laboratory of Immunology, Department of Biomolecular
Sciences, Faculty of Medicine, Saga University, 5)Department of Dermatology, Graduate School of Medical and Dental Sciences, Kagoshima
University
2)

WS25-09-O/P

Regulation and cell fate of CCR2+ inflammatory monocytes in the development of T cell-dependent
autoimmune arthritis
1, 2)
1, 2)
1)
1)
1)
2)
〇 Hiroki Mukoyama , Yusuke Takeuchi , Daiya Ohara , Hitomi Watanabe , Gen Kondoh , Akio Morinobu ,Keiji Hirota1)
1)

Laboratory of Integrative Biological Science, Institute for Life and Medical Sciences, Kyoto University, Kyoto, Japan, 2)Department ofRheumatology and Clinical Immunology, Graduate School of Medicine, Kyoto University, Kyoto, Japan

WS25-12-O/P

Analysis of IL-6 secretion from synovial fibroblasts related to cell-to-cell interactions
1)
2)
1)
1)
1)
2, 3)
〇 Haruka Takahashi , Zhuohao Yang , Haruka Tsuchiya , Risa Yoshihara , Yumi Tsuchida , Mai Yamagishi ,
2)
4)
2)
5)
1, 6)
Yoshitaka Shirasaki , Sotaro Uemura , Takashi Funatsu , Sakae Tanaka , Tomohisa Okamura , Keishi Fujio1)
1)

Department of Allergy and Rheumatology, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan, 2)Graduate School of
Pharmaceutical Sciences, The University of Tokyo, Tokyo, Japan, 3)Live Cell Diagnosis, Ltd., Asaka, Japan, 4)Department of Biological Sciences,
Graduate School of Science, The University of Tokyo, Tokyo, Japan, 5)Department of Orthopaedic Surgery, Graduate School of Medicine, The
University of Tokyo, Tokyo, Japan, 6)Department of Functional Genomics and Immunological Diseases, Graduate School of Medicine, The
University of Tokyo, Tokyo, Japan76

WS25-13-O/P

Protective effect of Recombinant Human Thrombomodulin on Streptozotocin-induced diabetes
1)
1)
2)
1, 2)
1)
1, 2)
〇 Yuko Okano , Chisa Inoue , Valeria Fridman , Atsuro Takeshita , Kota Nishihama , Taro Yasuma ,
2)
2)
1)
2)
Masaaki Toda , Corina Gabazza , Yutaka Yano , Esteban Gabazza
1)

Department of Diabetes and Endocrinology Mie University Hospital Mie Japan, 2)Department of Immunology Mie University Mie Japan

WS25-15-O/P

DNAM-1 deficiency exacerbates Concanavalin A-induced acute liver injury through neutrophil infiltration
1, 2)
3, 4)
1, 3, 4)〇 Soichi Matsuo , Tsukasa Nabekura , Akira Shibuya
1)

Department of Immunology, Faculty of Medicine, University of Tsukuba, Japan, 2)Doctoral Program in Medical Science, Graduate School ofComprehensive Human Sciences, University of Tsukuba, Japan, 3)Life Science Center for Survival Dynamics, Tsukuba Advanced Research
Alliance (TARA), University of Tsukuba, Japan, 4)R&D Center for Innovative Drug Discovery, University of Tsukuba, Japan
WS25-16-O/P

Role of intrathrombotic CX3CR1-fractalkine axis during resolution on murine deep vein thrombosis model〇 Mizuho Nosaka, Yuko Ishida, Akihiko Kimura, Yumi Kuninaka, Naofumi Mukaida, Toshikazu Kondo
Department of Forensic Medicine, Wakayama Medical University

WS25-17-O/P

CD122-selective IL/2/antiIL-2 complex enhances the synergistic potentiation in the innate immunity andmemory T cells resulting strong anti-tumor effect〇 Kanako Shimizu, Masami Kawamura, Shin-Ichiro Fujii
RIKEN Center for Integrative Medical Sciences, Yokohama, Japan

December 9
WS26

T Cell activation and responses (human and Vitro)

13:00 ~ 14:15 Room B
Chairpersons: Kiyoshi Hirahara, Hiroko Nakatsukasa

T cells are crucial for shaping the adaptive immune responses against harmful pathogens. However, they are also involved in thepathogenesis of various immune-related inflammatory diseases. The appropriate activation of T cells via various signals suchas T cell receptor stimulation, costimulatory stimulation, and stimulation are essential for adequate immune responses in vivo.
However, the precise molecular mechanisms through which T cells are activated remain uncertain. The aim of this workshop
is to discuss the cutting-edge findings of the unique features of T cell activation and responses in various situations including
virus infection and anti-tumor therapies. We welcome active discussion. [Each presentation is expected to finish within 6
minutes followed by 2 minutes of discussion.]WS26-01-O/P

Composition of the UBASH3A signalosome emphasizes its negative regulatory function in TCR signaling
1)

2)〇 Daiki Mori , Bernard Malissen
1)

Regulation of Host Defense Team, Division of Microbiology and Immunology, Center for Infectious Disease Education and Research, Osaka
University , 2)Centre d'Immunologie de Marseille-Luminy, Aix-Marseille University
WS26-02-O/P

Regulation of the TNFR family co-signaling by TNF-related recombinant proteins
1)
1)
1)
1)
1)
1)
1)
〇 Takanori So , Ayaka Sato , Hodaka Nagai , Mitsuki Azuma , Nagito Shibui , Wakana Imai , Masashi Morita ,Naoto Ishii2)
1)

Laboratory of Molecular Cell Biology, Graduate School of Medicine and Pharmaceutical Sciences, University of Toyama, 2)Department ofMicrobiology and Immunology, Tohoku University Graduate School of Medicine
WS26-03-O/P

CD62L expression is regulated by the states of energy metabolism〇 Koji Kitaoka, Maiko Hajime, Yasuharu Haku, Kenji Chamoto, Tasuku Honjo
Division of Immunology and Genomic Medicine, Center for Cancer Immunotherapy and Immunobiology, Kyoto University Graduate School

WS26-04-O/P

Robust TCR signals control epigenetic conversion of conventional T cells to regulatory T cells throughmTORC1-dependent expression of TET proteins
1)

1)

2)

2)

1)

1, 2)

〇 Tomohide Kinoshita , Mai Ohno , Norihito Hayatsu , Reiko Ohnishi , Akira Nakajima , Shohei Hori
1)

Laboratory for Immunology and Microbiology, Graduate School of Pharmaceutical Sciences, The University of Tokyo, Tokyo, Japan, 2)RIKEN
Center for Integrative Medical Sciences, Tokyo, Japan77

WS26-05-O/P

Dynamic B-pocket remodeling is a basis for HLA class I molecules to bind peptides and lipopeptides
1, 2)
1, 2)
1, 2)
〇 Minori Asa , Daisuke Morita , Masahiko Sugita
1)
Laboratory of Cell Regulation, Institute for Life and Medical Sciences, Kyoto University, 2)Laboratory of Cell Regulation and Molecular Network,
Graduate School of Biostudies, Kyoto University

WS26-06-O/P

Binding of the CD4/CD8 coreceptor to an MHC molecule positively modulates CAR-T cell response
1)

1)

1)

1)

1)

1)

〇 Hiroaki Machiyama , Ei Wakamatsu , Arata Takeuchi , Hitoshi Nishijima , Masae Furuhata , Hiroko Toyota ,Maksim Mamonkin2), Malcolm K Brenner2), Tadashi Yokosuka1)
1)

Department of Immunology, Tokyo Medical University, Tokyo, Japan, 2)Center for Cell and Gene Therapy, Baylor College of Medicine, Houston,
TX, US

WS26-07-O/P

SCD2-mediated cooperative activation of IRF3-IRF9 regulatory circuit controls type I interferontranscriptome in CD4+ T cells〇 Toshio Kanno, Yusuke Endo, Takahiro Nakajima
Kazusa DNA Research Institute.

WS26-08-O/P

Generation of CTLs from iPSCs transduced with TCR genes: development of “TCR cassette” method
1)

2)

2)

1)

〇 Seiji Nagano , Koji Terada , Yasutoshi Agata , Hiroshi Kawamoto
1)

2)

Kyoto University, Kyoto, Japan, Shiga University of Medical Science, Shiga, Japan

WS26-09-O/P

Analysis of HLA-class-I unrestricted T cell receptors obtained from tumor infiltrating lymphocytes ofbreast cancer patients〇 Abdul Hayee, Satoshi Yamaguchi, Hiroshi Hamana, Kiyomi Shitaoka, Eiji Kobayashi, Tatsuhiko Ozawa,
Ha Thi Viet My, Atsushi Muraguchi, Hiroyuki Kishi
Department of Immunology, Faculty of Medicine, Academic Assembly, University of Toyama

WS27

Tumor Microenvironment, Metabolism

13:00 ~ 14:15 Room C
Chairpersons: Mamoru Harada, Haruka Wada

Although anti-cancer immunotherapy is approved as effective in treating various types of cancers, further studies are needed
to improve the therapeutic efficacy. For that reason, in this session, studies focusing on new anti-cancer immunotherapies,
metabolism, and tumor microenvironment are presented and discussed. Active and affirmative discussion is expected.

WS27-10-O/P

Combination immunotherapy targeting stearoyl-CoA desaturase 1 (SCD1) with immunosuppressive
activity
1, 2, 3), Tomonori Yaguchi1, 4), Akiko Kubo5), Takashi Iwata1, 3), Kenji Morii1, 4), Daiki Kato1), Shigeki Ohta1, 6),〇 Yuki Katoh
Makoto Suematsu5), Yutaka Kawakami1, 6)
1)Division of Cellular Signaling, Institute for Advanced Medical Research, Keio University School of Medicine, 2)Division of Anatomical Science,
Department of Functional Morphology, Nihon University School of Medicine, 3)Department of Obstetrics and Gynecology, Keio University
School of Medicine, 4)Department of Immunology and Genomic Medicine, Center for Cancer Immunotherapy and Immunobiology(CCII),
Graduate School of Medicine, Kyoto University, 5)Department of Biochemistry, Keio University School of Medicine, 6)Department of Immunology,
School of Medicine, International University of Health and Welfare

WS27-11-O/P

A novel immunotherapy using CCL19-expressing allogeneic mesenchymal stromal cells exert anti-tumor
effect by increasing CD103+ CD8+ T cells〇 Yuichi Iida, Mamoru Harada
Department of Immunology, Faculty of Medicine, Shimane University

WS27-13-O/P

Metabolic adaptation of cancer cells to escape from immune-editing process
1)

1)

2)

1)

〇 Sisca Ucche , Soichiro Sasaki , Kazuyoshi Takeda , Yoshihiro Hayakawa
1)2)

Section of Host Defences, Institute of Natural Medicine, University of Toyama, Laboratory of Cell Biology, Graduate School of Medicine,
Juntendo University

78

WS27-14-O/P

Spermidine activates Mitochondrial trifunctional complex MTP leading to enhanced fatty acid oxidation
FAO in CD8+ T cells and stronger anti-tumor immunity in combination PD-1 blockade
1, 2, 3)
, Kenji Chamoto1), Norimichi Nomura4), Ken Matsumoto5), Kazuhiko Sonomura6, 7),〇 Muna Al-Habsi
8)
Baihao Zhang , Yuki Sugiura9), Toshihiko Ogura5), Sidonia Fagarasan3, 8), Tasuku Honjo1)
1)

Division of Immunology and Genomic Medicine, Center for Cancer Immunotherapy and Immunobiology, Kyoto University Graduate School of
Medicine, Kyoto, Japan, 2)National Genetic Center, Ministry of Health, Muscat, Oman, 3)Division of Integrated High-Order Regulatory Systems,
Center for Cancer Immunotherapy and Immunobiology, Kyoto University Graduate School of Medicine, Kyoto University, Kyoto, Japan,
4)
Department of Cell Biology, Graduate School of Medicine, Kyoto University, Kyoto, Japan, 5)Department of Developmental Neurobiology,
Institute of Development, Aging and Cancer, Tohoku University, Miyagi, Japan, 6)Center for Genomic Medicine, Graduate School of Medicine,
Kyoto University, Kyoto, Japan, 7)Life Science Research Center, Technology Research Laboratory, Shimadzu Corporation, Kyoto, Japan.,
8)
Laboratory for Mucosal Immunity, Center for Integrative Medical Sciences, RIKEN Yokohama Institute, Yokohama, Japan, 9)Department ofBiochemistry and Integrative Biology, Keio University, Tokyo, Japan
WS27-16-O/P

Single-cell RNA-seq analysis of human tumor infiltrating T cells across multiple tumor types to discoverpotential targets for combination immunotherapy
1)
1)
1)
1)
1)
〇 Yoshinobu Koguchi , Tanisha Christie , Venkatesh Rajamanickam , Noah Simons , Wesley Rosales ,Laura Seestaller Wehr2), Niranjan Yanamandra2), Sue Griffin2), James Smothers2), Johanna Kaufmann3),
Brady Bernard1), William Redmond1)
1)

Earle A. Chiles Research Institute, Providence Cancer Institute, Portland, OR, USA, 2)Immuno-Oncology & Combinations Research Unit,
GlaxoSmithKline, Collegeville, PA, USA, 3)Codagenix, Farmingdale, NY, USA
WS27-20-O/P

IFN-α/β-mediated neuropeptide signaling augments malignancy of colon cancer cells
1)
1, 2)
1, 2)
1, 2)
1, 2)
1, 2)
〇 Hidemitsu Kitamura , Huihui Xiang , Yujiro Toyoshima , Naoki Okada , Shuhei Kii , Ko Sugiyama ,
5)
6)
4)
3)
3)
Toshihiro Nagato , Hiroya Kobayashi , Kazuho Ikeo , Shinichi Hashimoto , Mishie Tanino , Akinobu Taketomi2)
1)
Division of Functional Immunology, Institute for Genetic Medicine, Hokkaido University, Sapporo, Japan, 2)Department of Gastroenterological
Surgery I, Hokkaido University Graduate School of Medicine, Sapporo, Japan, 3)Department of Pathology, Asahikawa Medical University,
Asahikawa, Japan, 4)DNA Data Analysis Laboratory, National Institute of Genetics, Mishima, Japan, 5)Department of Molecular Pathophysiology,
Institute of Advanced Medicine, Wakayama Medical University, Wakayama, Japan, 6)Department of Surgical Pathology, Asahikawa Medical
University, Asahikawa, Japan

WS27-23-O/P

Immunosuppression-elicited Galectin-7 is a crucial metastatic enhancer of squamous cell carcinoma
1)
2)
1, 3)
1)
4)
3)
〇 Jianbo An , Yushi Nagaki , Midori Hoshizaki , Tomokazu Yamaguchi , Yuta Kuze , Yumiko Imai ,Satoru Motoyama2), Yutaka Suzuki4), Keiji Kuba1)
1)

Department of Biochemistry and Metabolic Science, Akita University Graduate School of Medicine, Akita, Japan, 2)Department of Surgery,
Akita University Graduate School of Medicine, Akita, Japan, 3)Laboratory of Regulation of Intractable Infectious Diseases, National Institute of
Biomedical Innovation, Health and Nutrition, Osaka, Japan, 4)Department of Medical Genome Sciences, Graduate School of Frontier Sciences,
The University of Tokyo, Chiba, Japan
WS27-24-O/P

A novel prognostic gene signature of amino acid metabolism pathways under lung adenocarcinoma
tumor immune microenvironment
1)

1)

2)

1)

〇 Huihui Xiang , Rika Kasajima , Tetsuro Sasada , Yohei Miyagi
1)

Molecular Pathology & Genetics Division, Kanagawa Cancer Center Research Institute, Yokohama, Japan, 2)Division of Cancer Immunotherapy,
Kanagawa Cancer Center Research Institute, Yokohama, Japan

79

WS28

Infection and Immunity III

13:00 ~ 14:15 Room D
Chairpersons: Hiroyuki Oshiumi, Miwa Sasai

Humoral and cellular immunity are both important to eradicate virus and prevent reinfection. Antibodies neutralize virus
infectivity, whereas viruses evade host immune responses via mutations on their genome and sometimes utilize antibodies toenhance their infection. T cells support those humoral immunity or directly kill infected cells, and thus viral mutations also affectT cell-mediated immune responses. Moreover, cellular intrinsic mechanisms are also crucial for antiviral responses. Recent
studies have elucidated the mechanisms underlying the host-virus conflict. This workshop is focused on antiviral humoral,
cellular, and molecular immunity and viral escape from the immune system.

WS28-01-O/P

Therapeutic efficacy of monoclonal antibodies and antivirals against SARS-CoV-2 Omicron variants in thehamster model
1, 2)
1)
1, 2)
1, 2)
1)
1, 2)
1, 2)
〇 Ryuta Uraki , Maki Kiso , Masaki Imai , Seiya Yamayoshi , Mutsumi Ito , Michiko Ujie , Yuri Furusawa ,1)
1)
1)
1, 2, 3)
Atsuhiro Yasuhara , Kiyoko Iwatsuki-Horimoto , Yuko Sakai-Tagawa , Yoshihiro Kawaoka
1)
Division of Virology, Institute of Medical Science, University of Tokyo, 2)The Research Center for Global Viral Diseases, National Center
for Global Health and Medicine Research Institute, 3)Department of Pathobiological Sciences, School of Veterinary Medicine, University of
Wisconsin-Madison

WS28-02-O/P

Acquisition of resistance to wild-type spike-immune sera by emerging SARS-CoV-2 variants
1, 2)
1, 2)
1, 2)
1, 2)
1, 2)
〇 Yafei Liu , Hui Jin , Wataru Nakai , Masako Kohyama , Hisashi Arase1)

Department of Immunochemistry, Research Institute for Microbial Diseases, Osaka University, Japan, 2)Laboratory of Immunochemistry, WPI
Immunology Frontier Research Center, Osaka University, Japan
WS28-03-O/P

The SARS-CoV-2 Omicron BA.1 spike G446S potentiates antiviral T cell immunity
1)

1)

2)

3)

2)

1)

〇 Chihiro Motozono , Mako Toyoda , Hiroshi Hamana , Keiko Udaka , Hiroyuki Kishi , Takamasa Ueno
1)

2)

Division of infection and immunity, Joint research center for Human Retrovirus infection, Kumamoto University, Department of Immunology,
Faculty of Medicine, Academic Assembly, University of Toyama, 3)Department of Immunology, Kochi University
WS28-04-O/P

Analysis of SARS-CoV-2 pathogenicity in COVID-19 cynomolgus macaque model reflecting human
COVID-19 pathological conditions〇 Emiko Urano, Tomotaka Okamura, Yasuhiro Yasutomi
Tsukuba Primate Research Center, National Institutes of Biomedical Innovation, Health and Nutrition

WS28-05-O/P

Role of histone ubiquitination in SARS-CoV2 and influenza virus infection〇 Yumiko Imai, Yasuha Kinugasa, Midori Hoshizaki, Mara Llamas Covarrubias
National Institutes of Biomedical Innovation, Health and Nutrition, Center for Vaccine & Adjuvant Research

WS28-06-O/P

Characterization of airway M cell: a potential contribution to respiratory diseases
1, 2)
1)
1, 3)
1, 3)
4)
1)
〇 Shunsuke Kimura , Shingo Kawai , Takahiro Yamada , Yutaka Nakamura , Shinichiro Sawa , Hase Koji
1)

Division of Biochemistry, Faculty of Pharmacy, Keio University, Tokyo, Japan, 2)PRESTO, Japan Science and Technology Agency, Saitama,
Japan, 3)Department of Microbiology and Immunology, School of Pharmaceutical Sciences, Wakayama Medical University, Wakayama, Japan.,
4)
Division of Mucosal Immunology, Research Center for Systems Immunology, Medical Institute of Bioregulation, Kyushu University
WS28-07-O/P

Immune Profiling of HTLV-1-Specific CTLs in Peripheral Blood and Cerebrospinal Fluid of HAM/TSP
Patients for Elucidation of Immunoregulatory Mechanisms and Novel Biomarker Discovery
1)

1)

2)

3)

2)

1)

〇 Benjy Jek Yang Tan , Kenji Sugata , Tomoo Sato , Mitsuharu Ueda , Yoshihisa Yamano , Yorifumi Satou
1)

2)

Division of Genomics & Transcriptomics, Joint Research Center for Human Retrovirus Infection, Kumamoto University, Department ofRare Diseases Research, School of Medicine, St. Marianna University, Kanagawa, 3)Department of Neurology, Kumamoto University Hospital,
Kumamoto
WS28-08-O/P

Investigation of the role of follicular CD8 T cells for reducing viral reservoirs under cART treatment
1)

1)

2)

1)

1)

3)

〇 Ayaka Washizaki , Shokichi Takahama , Tomotaka Okamura , Takuto Nogimori , Yuji Masuta , Yorifumi Satou ,Takuya Yamamoto1, 4, 5)
1)
Laboratory of Immunosenescence, National Institutes of Biomedical Innovation, Health and Nutrition, Osaka, Japan, 2)Tsukuba primate research
center, National Institutes of Biomedical Innovation, Health and Nutrition, Ibaraki, Japan, 3)Division of Genomics and Transcriptomics, Joint
Research Center for Human Retrovirus Infection, Kumamoto University, Kumamoto, Japan, 4)Laboratory of Aging and Immune Regulation,
Graduate School of Pharmaceutical Sciences, Osaka University, Osaka, Japan, 5)Department of Virology and Immunology, Graduate School of
Medicine, Osaka University, Osaka, Japan

80

WS29


Dendritic cells and macrophages-3: Regulation of cytokine production, pathogenesis
13:00 ~ 14:15 Room E
Chairpersons: Chiharu Nishiyama, Kensuke Miyake

Macrophages, dendritic cells, and neutrophils sense various innate stimuli and produce inflammatory cytokines to quickly
respond to pathogen intrusion. However, aberrant activation of these innate immune cells is rather harmful to the host, whichis associated with pathogenesis of various inflammatory diseases. Therefore, the production of inflammatory cytokines fromtheses myeloid cells needs to be tightly regulated by a variety of mechanisms, including epigenetic regulation and receptormediated intracellular events. In this session, we will first discuss the regulatory mechanisms of inflammatory cytokine
production from macrophages and dendritic cells. Secondly, we will aim to understand how macrophages, dendritic cells andneutrophils are associated with inflammatory diseases, including autoinflammatory disease and glomerulonephritis.

WS29-01-O/P

Regulatory Mechanism in Innate Immune Response by a CCCH-type Zinc Finger Protein, ENZ-1〇 Norisuke Kano, Daisuke Ori, Takumi Kawasaki, Taro Kawai
Division of Science and Technology, Laboratory of Molecular Immunobiology, Nara Institute of Science and Technology, Nara, Japan

WS29-02-O/P

Regulation of Il6 Expression by a Single CpG methylation in the Il6 locus〇 Takumi Kawasaki, Benedict Shi Xiang Lian, Daisuke Ori, Taro Kawai
Nara Institute of Science and Technology (NAIST), Laboratory of Molecular Immunobiology

WS29-05-O/P

O6-alkylguanine DNA alkyltransferase (MGMT) Regulates Beta-Glucan-induced Trained Immunity inMacrophages
1, 2, 3), Salisa Benjaskulluecha1, 2), Atsadang Boonmee3), Thitiporn Pattarakankul3, 4),〇 Tanapat Palaga
3)
Benjawan Wongprom
1)

Center of Excellence in Immunology and Immune-Mediated Diseases, Chulalongkorn University, Bangkok, Thailand, 2)Interdisciplinary
Graduate Program in Medical Microbiology, Graduate School, Chulalongkorn University, Bangkok, Thailand, 3)Department of Microbiology,
Faculty of Science, Chulalongkorn University, Bangkok, Thailand, 4)Center of Excellence in Advanced Materials and Biointerfaces, Chulalongkorn
University, Bangkok, Thailand
WS29-06-O/P

Novel function of clathrin heavy chain regulating NLRP3 inflammasome formation via endocytosis inmacrophages
1)

1)

1)

1)

2)

〇 Hiep Hung Huynh , Eri Koike , Masumi Shimizu , Rimpei Morita , Akihiko Yoshimura
1)

2)

Nippon Medical School, Tokyo, Japan, Keio University School of Medicine, Tokyo, Japan

WS29-10-O/P

Dendritic and T cell abnormalities in an autoinflammatory disease with interstitial lung disease and type
I interferonopathy caused by a disability of retrograde protein trafficking
1)
1)
1, 2)
3, 4, 5)
, Kazushi Izawa5), Ryuta Nishikomori6),〇 Takashi Kato , Izumi Sasaki , Hiroaki Hemmi , Yoshitaka Honda
1)
Tsuneyasu Kaisho
1)
Department of Immunology, Institute of Advanced Medicine, Wakayama Medical University, Wakayama, Japan, 2)Laboratory of Immunology,
Faculty of Veterinary Medicine, Okayama University of Science, Imabari, Japan, 3)Institute for the Advanced Study of Human Biology (ASHBi),
Kyoto University, Kyoto, Japan, 4)Department of Immunology, Kyoto University Graduate School of Medicine, Kyoto Japan, 5)Department ofPediatrics, Kyoto University Graduate School of Medicine, Kyoto Japan, 6)Department of Pediatrics and Child Health, Kurume University Schoolof Medicine, Kurume, Japan

WS29-11-O/P

The role of RNase T2 in macrophage homeostasis.
1)

1)

1)

1)

2)

3)

〇 Ryota Sato , Kaiwen Liu , Takuma Shibata , Ryutaro Fukui , Katsuaki Hoshino , Tsuneyasu Kaisho ,Kensuke Miyake1)
1)
Division of Innate Immunity, The Institute of Medical Science, The University of Tokyo, Tokyo, Japan., 2)Department of Immunology, Facultyof Medicine, Kagawa University, Kagawa, Japan., 3)Department of Immunology, Institute of Advanced Medicine, Wakayama Medical University,
Wakayama, Japan.

WS29-14-O/P

FROUNT inhibitor disulfiram ameliorates crescentic glomerulonephritis through the inhibition of
monocytes/macrophage migration and activation
1, 2)
1)
1)
1)
1)
1)
〇 Etsuko Toda , Anri Sawada , Kazuhiro Takeuchi , Mika Terasaki , Shinobu Kunugi , Yasuhiro Terasaki ,2)
2)
1)
Kouji Matsushima , Yuya Terashima , Akira Shimizu
1)
Department of Analytic Human Pathology, Nippon Medical School, Tokyo, Japan, 2)Division of Molecular Regulation of Inﬂammatory and
Immune Diseases, Research Institute for Biomedical Sciences, Tokyo University of Science, Chiba, Japan81

WS29-15-O/P

The leukotriene B4-BLT1 axis in neutrophils exacerbates crescentic glomerulonephritis
1, 2)
1, 3)
1, 4)
1)
1, 2)
〇 Masatsugu Oh-Hora , Ryotaro Shioda , Airi Jo-Watanabe , Toshiaki Okuno , Kazuko Saeki ,3)3)1)
Maiko Nakayama , Yusuke Suzuki , Takehiko Yokomizo
1)
Department of Biochemistry, Juntendo University Graduate School of Medicine, 2)Laboratory of Molecular Immunology, Immunology Frontier
Research Center, Osaka University, 3)Department of Nephrology, Juntendo University Faculty of Medicine, 4)AMED-PRIME, Japan Agency for
Medical Research and Development

WS30

Innate immunity (2) Innate recognition and signaling

13:00 ~ 14:15 Room F
Chairpersons: Sho Yamasaki, Minako Ito

Studies of innate immunity has revealed that a variety of pattern recognition receptors(PRRs) sense pathogen associatedmolecular patterns (PAMPs) such as LPS or viral RNA followed by induction of innate immune response against bacterial andvirus infection. Also, danger-associated molecular patterns (DAMPs) such as HMGB-1 or MRP-14 induce sterile inflammationin addition to PAMPs as well. Such inflammation by exogenous and endogenous ligands should be properly controlled forhomeostasis. In this workshop, we will discuss innate immune response focusing on the point of innate recognition and theirsignaling. We welcome active discussion and communication by all participants.

WS30-03-O/P

Activation of MyD88- and TRIF-mediated Signaling Pathways by Alcaligenes Lipid A for Efficient Antigen
Presentation and T Cell Differentiation by Dendritic Cells
2)
1, 2)
2)
2)
1, 2)
1)
1, 2)
〇 Xiao Sun , Koji Hosomi , Atsushi Shimoyama , Ken Yoshii , Zilai Liu , Haruki Yamaura , Davie Kenneth ,1)
1, 3)
4, 5, 6)2)
1, 2, 4, 7, 8)Azusa Saika , Takahiro Nagatake , Hiroshi Kiyono, Koichi Fukase , Jun Kunisawa
1)

National Institutes of Biomedical Innovation, Health and Nutrition, Osaka, Japan, 2)Osaka University, Osaka, Japan, 3)Meiji University, Tokyo,
Japan, 4)The University of Tokyo, Tokyo, Japan, 5)University of California San Diego (UCSD), San Diego, CA, United States, 6)Chiba University,
Chiba, Japan, 7)Kobe University, Kobe, Japan, 8)Waseda University, Tokyo, Japan

WS30-05-O/P

Withdrawn

WS30-07-O/P

NOP16, a novel epigenetic modifier, suppresses the excessive innate inflammatory response by
regulating cellular stress〇 Ken Takashima, Yohana Mtali, Hiroyuki Oshiumi
Department of Immunology, Faculty of Life Sciences, Kumamoto University, Kumamoto, Japan

WS30-08-O/P

A lethal cross-talk between innate immune and adrenergic receptor signaling〇 Shuto Tanaka, Masataka Kawakita, Kazuhiko Takahara
Laboratory of Immunobiology, Graduate School of Biostudies, Kyoto University, Kyoto, Japan.

WS30-13-O/P

Glucagon-like Peptide-1 Receptor Agonist ameliorates inflammatory myopathies via suppressing muscle
fiber necroptosis〇 Mari Kamiya, Marina Tsuchida, Hirokazu Sasaki, Natsuka Umezawa, Shinsuke Yasuda
Department of Rheumatology, Graduate School of Medical and Dental Sciences, Tokyo Medical and Dental University (TMDU)

WS30-16-O/P

Kinetics of signaling via common Fc receptor γ (FcRγ) chain determine dendritic cell responses byaltering chromatin status
1, 2, 3)〇 Miyuki Watanabe, Sho Yamasaki1, 2, 4)

1)
Department of Molecular Immunology, Research Institute for Microbial Diseases, Osaka University, Osaka, Japan, 2)Laboratory of Molecular
Immunology, Immunology Frontier Research Center, Osaka University, Osaka, Japan, 3)Division of Mucosal Immunology, Research Center for
Systems Immunology, Medical Institute of Bioregulation, Kyushu University, Fukuoka, Japan, 4)Center for Infectious Disease Education andResearch (CiDER), Osaka University, Osaka, Japan

WS30-19-O/P

The Ragulator complex regulates NLRP3 inflammasome activation through interaction with HDAC6〇 Kohei Tsujimoto, Tatsunori Jo, Hyota Takamatsu, Atsushi Kumanogoh
Department of Respiratory Medicine and Clinical Immunology, Graduate School of Medicine, Osaka University

82

WS31

Autoimmunity

13:00 ~ 14:15 Room G
Chairpersons: Hiroaki Niiro, Keiji Hirota

Both effector innate and adaptive immune cells are involved in the development of autoimmunity. In addition, chemokinesand cytokines play an important role in the aberrant recruitment and dysfunction of these immune cells. On the other hand,autoimmunity can be counteracted by suppressive immune cells such as regulatory T cells (Tregs), which have potential
therapeutic applications. MHC is a well-known molecule associated with susceptibility to autoimmune diseases. Notably,
ectopic expression of MHC on non-immune cells leads to autoimmunity through a unique mechanism. Autoantibodies are often
useful for subclassifying disease phenotypes and exert effector functions in the formation of immune complexes. In view of theabove, we have selected 8 outstanding abstracts for this session and look forward to active participation and discussion.

WS31-01-O/P

Moesin deficiency leads to the local CXCL13 expression and inflammation in the kidney〇 Satoko Ichioka, Hiroki Satooka, Takako Hirata
Department of Fundamental Biosciences, Shiga University of Medical Science

WS31-02-O/P

Neutrophils exacerbate the pathogenesis of pulmonary fibrosis by cleaving IL-33
1)
1, 2)
1, 2)
〇 Yuki Hara , Yasutaka Motomura , Kazuyo Moro
1)
Laboratory for Innate Immune Systems, Department of Microbiology and Immunology, Graduate School of Medicine, Osaka University, Osaka,
Japan, 2)Laboratory for Innate Immune Systems, RIKEN IMS, Kanagawa, Japan

WS31-03-O/P

Tissue-specific deficiency of clonally expanded regulatory T cells underlies tissue-restricted inflammationin Foxp3A384T mutant mice
〇 Yoshimichi Hoshiya
Laboratory of Immunology and Microbiology, Graduate School of Pharmaceutical Sciences, The University of Tokyo, Tokyo, Japan

WS31-04-O/P

Treatment for autoimmune diseases with engineered exosome
1)
2, 3)
2)
2, 3)
〇 Shota Imai , Tomoyoshi Yamano , Xiabing Lyu , Rikinari Hanayama
1)

Department of immunology, School of Frontier Science initiative division of Nano life science, Kanazawa University, Kanazawa, Japan,
Department of Immunology, Graduate School of Medical Sciences, Kanazawa University, Kanazawa, Japan, 3)WPI Nano Life Science Institute(NanoLSI), Kanazawa University, Kanazawa, Japan2)

WS31-05-O/P

A new transcriptional mechanism of ectopic MHC class II expression induced by IFN-γ
1, 2)
1, 2)
1, 2)
1, 2)
〇 Wataru Nakai , Yuta Shimizu , Masako Kohyama , Hisashi Arase1)

Department of Immunochemistry, Research Institute for Microbial Diseases, Osaka University, 2)Laboratory of Immunochemistry, WPI
Immunology Frontier Research Center, Osaka University
WS31-06-O/P

Autoantibodies to the Survival of Motor Neuron (SMN) complex as a novel marker for pulmonary arterial
hypertension in patients with mixed connective tissue disease (MCTD)
1)
2, 3)
1)
1)
2)
1)
〇 Yasuyuki Todoroki , Minoru Satoh , Satoshi Kubo , Shumpei Kosaka , Shin Tanaka , Shingo Nakayamada ,1)
Yoshiya Tanaka
1)
First Department of Internal Medicine, University of Occupational and Environmental Health, Japan, 2)Department of Human, Information andLife Sciences, University of Occupational and Environmental Health, Japan, 3)Kitakyushu Yahata Higashi Hospital

WS31-07-O/P

RNase-induced Fc gamma receptor stimulation of Ro60/SSA- and La/SSB- immune complexes.
1, 2, 3)

〇 Ryota Naito
Hisashi Arase2, 3), Koichiro Ohmura1), Shuhei Higuchi2, 3), Wataru Nakai2, 3), Masako Kohyama2, 3), Akio Morinobu1),

1)

Department of Rheumatology and Clinical Immunology, Graduate School of Medicine, Kyoto University, Kyoto, Japan, 2)World PremierInternational Immunology Frontier Research Center, Osaka University, Suita, Japan, 3) Research Institute for Microbial Diseases, Osaka
University, Suita, Japan
WS31-08-O/P

HLA analysis of the Nivolumab-induced ACTH deficiency
1)

2)

2)

3)

1)

1)

〇 Keiko Udaka , Mitsuru Nishiyama , Shogo Funakoshi , Takashi Shiina , Takeyuki Shimizu , Toshihiro Komatsu ,Hiroshi Hamana4), Hiroyuki Kishi4), Kousuke Onoue5), Yuki Tanaka5), Tetsu Aihara6), Youki Nakagawa6)
1)
Department of Immunology, School of Medicine, Kochi University, Nankoku, Japan, 2)Department of Endocrinology, Metabolism andNephrology, School of Medicine, Kochi University, Nankoku, Japan, 3)Division of Basic Medical Science and Molecular Medicine, Departmentof Molecular Life Science, Tokai University, Isehara, Japan, 4)Department of Immunology, Faculty of Medicine, Academic Assembly, Universityof Toyama, Toyama, Japan, 5)AI Drug Development Division, NEC Corporation, Tokyo, Japan, 6)Advanced Science Course, School of Medicine,
Kochi University, Nankoku, Japan83

Poster○ : PresenterDecember 7
WS01

T cell development (thymus and homeostasis)WS01-01-O/P

Notch signaling triggers T-lineage program via Tcf7-dependnent and -independent mechanisms〇 Ken-Ichi Hirano, Katsuto Hozumi, Hiroyuki Hosokawa
Department of Immunology, Tokai University School of Medicine, Kanagawa, Japan

WS01-02-O/P

Phosphorylation of Runx proteins controls thymocyte fate
〇 Chihiro Ogawa, Kazuki Okuyama, Satoshi Kojo, Sawako Muroi, Ichiro Taniuchi
Riken, Center for Integrative Medical Sciences, Laboratory for Transcriptional Regulation, Yokohama, Japan

WS01-03-O/P

THEMIS acts in the cytoplasm and nucleus to regulate T cell differentiation〇 Kiyokazu Kakugawa, Hilde Cheroutre
Laboratry for ImmuneCrosstalk, RIKEN Center for Integrative Medical Science

WS01-04-O/P

Induction of central tolerance by arginine methylation〇 Ryunosuke Muro, Takeshi Nitta, Hiroshi Takayanagi
Department of Immunology, Graduate School of Medicine and Faculty of Medicine, The University of Tokyo

WS01-05-O/P

Isolation of thymic self-reactive T cells with differentiation preference for regulatory T cells
1, 2)
1, 2)
〇 Ryoji Kawakami , Shimon Sakaguchi
1)Institute for Life and Medical Sciences, Kyoto University, Kyoto, Japan, 2)Immunology Frontier Research Center, Osaka University, Osaka, Japan

WS01-06-O/P

	Excess proliferation and activation of self-reactive memory-phenotype CD4+ T lymphocytes are tonicallyinhibited by regulatory T cells in steady state〇 Jing Li, Ziying Yang, Akihisa Kawajiri, Kosuke Sato, Shunichi Tayama, Yuko Okuyama, Naoto Ishii, Takeshi Kawabe
Department of Microbiology and Immunology, Tohoku University Graduate School of Medicine, Sendai, Japan

WS01-07-O/P

Long-term caloric restriction ameliorates T cell immunosenescence in mice
〇 Sachi Tanaka, Katsunori Endo
Shinshu University, Nagano, Japan

WS01-08-P

	Reinforcement learning in the process of gene expression〇 Tomoyuki Yamaguchi
Research Institute, Nozaki Tokushukai Hospital

WS01-09-P	Investigation of regulatory machinery of Cd8a expression in cytotoxic T cells via the CRISPR/Cas9 screen
system〇 Jiawen Zheng, Ichiro Taniuchi
Laboratory for Transcriptional Regulation, IMS, RIKEN Yokohama, Japan

WS01-10-P

Cohesin-mediated chromatin regulation in the regulatory T cells is required for the immune homeostasis〇 Kentaro Fujiwara, Kazuko Miyazaki, Hiroshi Kawamoto, Masaki Miyazaki
Kyoto University, Institute for Life and Medical Sciences, Kyoto, Japan

WS01-11-P	Synergistic action between E2A and Notch signal determines the cell fate of T cell versus innate lymphoidcell in the thymus〇 Kazuko Miyazaki, Hiroshi Kawamoto, Masaki Miyazaki
Institute for Life and Medical Sciences, Kyoto University

WS01-12-P

Notch-dependent functional conversion of Runx1 at the initiation of T-lineage program〇 Yuichi Kama, Katsuto Hozumi, Hiroyuki Hosokawa
Department of Immunology, Tokai University School of Medicine

WS01-13-P

Role of CD69 on thymic regulatory T cell development〇 Yukihiro Endo, Tastuya Ueno, Ichita Hasegawa, Yangsong Wang, Ryo Nasu, Motoko Kimura
Department of Experimental Immunology, Graduate School of Medicine, Chiba University

87Lck interactomes using two BioID methods in miceWS01-14-P

1, 2)
1)〇 Junji Harada , Ichiro Taniuchi
1)

Laboratory for Transcriptional Regulation, IMS, RIKEN, Kanagawa, Japan, 2)Department of RIKEN Molecular and Chemical Somatology,
Graduate School of Medical and Dental Sciences, Tokyo Medical and Dental University, Tokyo, Japan

WS01-15-P

	Self-reactive memory-phenotype CD4+ T lymphocytes can induce mild and systemic inflammation bydifferentiating into effector and regulatory T cells
1, 2)
1)
1)
1)
1)
1)
1)
〇 Akihisa Kawajiri , Jing Li , Ziying Yang , Keita Koinuma , Kosuke Sato , Shunichi Tayama , Yuko Okuyama ,
2)
1)
3)
4)
1, 3)
Hideo Harigae , Naoto Ishii , Jinfang Zhu , Kwang Soon Kim , Takeshi Kawabe
1)

Department of Microbiology and Immunology, Tohoku University Graduate School of Medicine, Sendai, Japan., 2)Department of Hematology,
Tohoku University Graduate School of Medicine, Sendai, Japan., 3)Molecular and Cellular Immunoregulation Section, Laboratory of Immune
System Biology, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, USA., 4)Department of Life
Sciences, Pohang University of Science and Technology, Pohang, Republic of Korea

Role of central tolerance in tumor progression

WS01-16-P〇 Yangsong Wang, Ryo Nasu, Ichita Hasegawa, Yukihiro Endo, Shunka Kanou, Motoko Y Kimura
Department of Experimental Immunology, Graduate School of Medicine, Chiba University

Role of HIF-1α in T cell behavior

WS01-17-P〇 Hidefumi Kojima
Division of Host Defense, Research Center for Advanced Medical Science Dokkyo Medical Univ. Sch. of Med.

The critical role of Rap1GAPs in T cell recirculation and egress from lymph node

WS01-18-P〇 Shunsuke Horitani , Yoshihiro Ueda , Yuji Kamioka , Naoyuki Kondo , Yoshiki Ikeda , Takataro Fukuhara ,Makoto Naganuma1), Tatsuo Kinashi2)
1)

2)

2)

2)

2)

1)

1)

Division of Gastroenterology and Hepatology, the third Department of Internal Medicine, 2)Department of Molecular Genetics, Institute of
Biomedical Science, Kansai Medical University
WS01-19-P

	The immunosuppressive effects of gallate-type procyanidin through modulating cell metabolism in CD4+
T cells〇 Katsunori Endo, Sachi Tanaka
Shinshu University, Nagano, Japan

cDC1-dependent generation of memory CD4 T cells

WS01-20-P〇 Kana Matsuo, Kokoro Ohki, Koji Tokoyoda
Division of Immunology, School of Life Science, Faculty of Medicine, Tottori University, Yonago, Japan

Regulatory T cell-dependent maintenance of memory T helper cells in vivo

WS01-21-P〇 Sano Nagano, Uki Kimura, Mei Sakagami, Koji Tokoyoda
Division of Immunology, School of Life Science, Faculty of Medicine, Tottori University, Yonago, Japan

December 7
WS02

Anti-tumor Effectors, Ag presentation

WS02-01-P

	T cell receptor repertoire analysis revealed tissue tropism of tumor-reactive T-cell clones in cell cycle
reporter mice
1)
1, 2)
1)
3)
1)
1)
〇 Mikiya Tsunoda , Hiroyasu Aoki , Haruka Shimizu , Munetomo Takahashi , Haru Ogiwara , Shigeyuki Shichino ,1)
1)
Kouji Matsushima , Satoshi Ueha
1)
Division of Molecular Regulation of Inflammatory and Immune Diseases, Research Institute for Biomedical Sciences, Tokyo University of
Science, Chiba, Japan, 2)Department of Hygiene, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan, 3)Faculty of Medicine,
The University of Tokyo

WS02-02-O/P	T-Cell Rejuvenation: a novel approach to partially reprogram T cells to improve their immunotherapeutic
properties〇 Raul Vizcardo, Yasuhiro Yamazaki, Takuya Maeda, Yin Huang, Naritaka Tamaoki, Burak Kutlu, Jessica Fioravanti,
Shobha Potluri, Nicholas P. Restifo
Lyell Immunopharma Inc, South San Francisco, CA, USA88WS02-03-O/P	scRNAseq analysis revealed that activation of progenitor-like Tex population in tumor elicited a strong
effector function in the later population in Socs3 cKO mice
〇 Setsuko Mise-Omata, Akihiko Yoshimura
Keio University School of Medicine, Department of Microbiology and Immunology, Tokyo, JAPAN

WS02-04-O/P

CD69 regulates anti-tumor CD8T cell responses〇 Ryo Nasu, Yangsong Wang, Yukihiro Endo, Ichita Hasegawa, Tatsuya Ueno, Yukiyoshi Mita,
Shinichiro Motohashi, Toshinori Nakayama, Motoko Y. Kimura
Graduate school of Medicine, Chiba University

WS02-05-P

Liver mononuclear cells-derived NK cells for treatment of hepatocellular carcinoma〇 Xin Hu, Masayuki Fujino, Xiao-Kang Li
Division of Transplantation Immunology, National Research Institute for Child Health and Development

WS02-06-O/P

Antitumor effect of anti-HLA-F antibody on colon cancer in patient-derived xenografts (PDX) model〇 Noriko Ouji-Sageshima, Masahiro Kitabatake, Ryutaro Furukawa, Toshihiro Ito
Department of Immunology, Nara Medical University, Nara, Japan

WS02-07-O/P

Consensus molecular subtypes specific roles of γδ T cells in colorectal cancer

1, 2)
1, 2)
1)
2)
3)
4)
〇 Toshiyasu Suzuki , Anna Kilbey , Rachel Ridgway , Hannah Hayman , Ryan Bryne , Michael Verzi ,
5)
3)
2)
6)
1, 2)
1, 2)
Simon Leedham , Philip Dunne , Joanne Edwards , Adrian Hayday , Owen Sansom , Seth Coffelt
1)

Cancer Research UK Beatson Institute, Glasgow, UK, 2)Institute of Cancer Sciences, University of Glasgow, Glasgow, UK, 3)School of Medicine,
Dentistry and Biomedical Sciences, Queen’s University, Belfast, UK, 4)Department of Genetics, Human Genetics Institute of New Jersey, Rutgers
Cancer Institute of New Jersey, Rutgers University, New Brunswick, New Jersey, USA, 5)Nuffield Department of Medicine, Oxford University,
Oxford, UK, 6)The Francis Crick Institute, London, UK
WS02-08-O/P

	Alpha-galactosylceramide-loaded antigen-presenting cells induce direct cytotoxicity and adjuvant effects
of induced pluripotent stem cell-derived natural killer T cells
1, 2)
1)
1)
1)
1)
1)
〇 Takahiro Aoki , Genta Kitahara , Momoko Okoshi , Midori Kobayashi , Munechik Yamaguchi , Hiroko Okura ,Masami Kawamura3), Tomonori Iyoda3), Kanako Shimizu3), Shin-Ichiro Fujii3), Shinichiro Motohashi2), Haruhiko Koseki1)
1)

Laboratory for Developmental Genetics, RIKEN Center for Integrative Medical Science, 2)Medical immunology, Graduate School of Medicine,
Chiba University, 3)Laboratory for Immunotherapy, RIKEN Center for Integrative Medical Science
WS02-09-P

	Anti-NKT cell antibody treatment enhances anti-tumor activity of NKT cells toward CD1d (-) tumors in a
CD32 dependent manner〇 Mariko Takami, Shinichiro Motohashi
Graduate School of Medicine, Chiba University, Chiba, Japan

WS02-10-P	Blockade of aryl hydrocarbon receptor (AhR) signaling enhances anti-tumor efficacy of iNKT cell-based
immunotherapy〇 Ayana Ishii, Mariko Takami, Shinichiro Motohashi
Department of Medical Immunology, Graduate School of Medicine, Chiba University, Chiba, Japan

WS02-11-P	Bioinformatic analysis of glioblastoma patient samples revealed a novel immunoregulatory pathway
initiated by MAIT cells〇 Masaki Terabe, Taijun Hana
Neuro-Oncology Branch, NCI, USA

WS02-12-P

	B16 melanoma cells that survive cytotoxic agents are recognized by host immunity but evade
immunological elimination〇 Yukie Ando, Sara Hatazawa, Akihiro Nakamura, Yutaka Horiuchi, Takashi Murakami
Dept. Microbiol., Fac. Med., Saitama Med. Univ.

WS02-13-P

NLRC5 confers to immune response upon cancer ICI therapy and serves as a prediction biomarker〇 Xin Sun , Toshiyuki Watanabe , Ning An , Hideo Yagita , Koichi Kobayashi
1)

2)

1)

3)

1)

1)

Department of Immunology, Faculty of Medicine and Graduate School of Medicine, Hokkaido University, Sapporo, Japan, 2)Hokkaido Medical
Center for Rheumatic Diseases, Sapporo, Japan, 3)Department of Immunology, Juntendo University School of Medicine, Tokyo, Japan89

WS02-14-P

Activation of MHC class I by controlling NLRC5 nucleocytoplasmic trafficking〇 Baohui Zhu, Ryota Ouda, Koichi Kobayashi
Department of Immunology, Hokkaido University Graduate School of Medicine, Sapporo, Japan

WS02-15-P

Identification of Zinc Finger protein as a novel regulator of MHC class I〇 Ryota Ouda , Noyuri Zama , Masashi Watanabe , Xin Sun , Shigetsugu Hatakeyama , Koichi Kobayashi
1)

1)

2)

1)

2)

1)

1)

2)

Department of Immunology, Faculty of Medicine and Graduate School of Medicine, Hokkaido University, Department of Biochemistry, Facultyof Medicine and Graduate School of Medicine, Hokkaido University
WS02-16-P

Rapid and efficient detection of neoantigens that elicit immune response and mediate tumor rejection
1)
1)
1, 2)
1)
〇 Serina Tokita , Takayuki Kanaseki , Satoru Matsumoto , Toshihiko Torigoe

1)

Department of Pathology, Sapporo Medical University, Sapporo, Japan, 2)Department of Surgery, IMS Sapporo Digestive Disease Center
General Hospital, Sapporo, Japan

WS02-17-P

	Proteogenomic approach to obtain a comprehensive picture of HLA-I immunopeptidome for Head andNeck Squamous Cell Carcinoma〇 Noriko Iwamoto , Takashi Shimada , Tarsem L. Moudgil , Ryan Meng , Alexa K. Dowell , Rom S Leidner ,William L Redmond2), Eric Tran2), Brian D Peining2), Yoshinobu Koguchi2), Bernard A. Fox2, 3)
1)

1)

2)

2)

2)

2)

1)

Technology Research Laboratory, Shimadzu Corporation, Japan, 2)Earle A. Chiles Research Institute, Providence Portland Cancer Institute,
Portland, OR, USA, 3)UbiVac, Portland. OR, USA

WS02-18-P	Direct identification of an HLA class II neoantigen that induces patient CD4+ T cell responses fromcolorectal cancer tissue
1)
1)
1)
1, 2)
〇 Satoru Matsumoto , Takayuki Kanaseki , Serina Tokita , Toshihiko Torigoe
1)

Department of Pathology, Sapporo Medical University School of Medicine, Hokkaido, Japan, 2)IMS Sapporo Digestive Disease Center General
Hospital, Hokkaido, Japan
WS02-19-P

Infiltration of tumor-specific regulatory T cells is mediated by MHC class II molecules on endothelial cells〇 Toshihiro Komatsu , Takeyuki Shimizu , Yoshiaki Kubota , Keiko Udaka
1)

1)

2)

1)

1)

2)

Department of Immunology, School of Medicine, Kochi University, Kochi, Japan, Departtment of Anatomy, School of Medicine, Keio
University, Tokyo, Japan
WS02-20-O/P

	Serine threonine kinase 24 (STK24) mediates immune evasion signals in tumors by inducing multiple
immunosuppressive molecules
1, 2)
1, 2)
2)
2, 3)
2)
〇 Aya Misawa , Shigeki Ohta , Ryotaro Imagawa , Yuki Katoh , Hidetoshi Sumimoto ,
4)
5)
5)
1, 2)
Naomi Goto-Matsumoto , Kenta Nakamura , Ryuhei Okuyama , Yutaka Kawakami
1)
Department of Immunology, School of Medicine, International University of Health and Welfare, Chiba, Japan, 2)Division of Cellular Signaling,
Institute for Advanced Medical Research, Keio University School of Medicine, Tokyo, Japan, 3)Division of Anatomical Science, Departmentof Functional Morphology, Nihon University School of Medicine, Tokyo, Japan, 4)Center for Basic Medical Research, School of Medicine,International University of Health and Welfare, Chiba, Japan, 5)Department of Dermatology, Shinshu University School of Medicine

WS02-21-P

Single-cell transcriptome reveals comprehensive immune profiles of T follicular helper cell lymphoma
1, 2)
3)
1)
2, 3)
2, 3)
〇 Sakurako Suma , Manabu Fujisawa , Yoshiaki Abe , Yasuhito Suehara , Shigeru Chiba ,2, 3, 4)Mamiko Sakata-Yanagimoto1)
Department of Hematology, Graduate School of Comprehensive Human Sciences, University of Tsukuba, Tsukuba, Japan., 2)Department of
Hematology, University of Tsukuba Hospital, Tsukuba, Japan., 3)Department of Hematology, Faculty of Medicine, University of Tsukuba, Tsukuba,
Japan., 4)Division of Advanced Hemato-Oncology, Transborder Medical Research Center, University of Tsukuba, Tsukuba, Japan

WS02-22-P

Spred2 downregulates cancer stemness in HCC cells,targeting on miR-506-3p and its downstream KLF4
〇 Tong Gao, Sachio Ito, Masahiro Fujisawa, Toshiaki Ohara, Teizo Yoshimura, Tianyi Wang, Akihiro Matsukawa
Graduate School of Medicine, Dentistry and Pharmaceutical Science,Okayama University,Okayama,Japan

WS02-23-P

	Basal extrusion of single-oncogenic mutant cells induces dome-like structures with macrophage
accumulation
1, 2)
1)
1)
〇 Miho Sekai , Takanobu Shirai , Yasuyuki Fujita
1)

Department of Molecular Oncology, Graduate School of Medicine, Kyoto University, 2)Eisai Co., Ltd.

WS02-24-P

AltR on epithelial cells recognizes MHC-I to eliminate precancerous cells〇 Shiyu Ayukawa , Nagisa Kamoshita , Takeshi Maruyama
1)

1)

2)

2)

2)

Adv. Sci. Eng., Waseda University., WIAS, Waseda University

90

WS02-25-P

	Loss of Phospholipase Cγ1 suppresses hepatocellular carcinogenesis through blockade of STAT3mediated cancer development in the tumor microenvironment〇 Sang-Kyu Ye, Eun-Bi Seo, Yong-Jin Kwon, Seul-Ki Kim, Songhee Lee, Hyunseung Lee, Chae Myung Kang,
Su Min Park, Kumhee Noh, Ae Jin Jeong
Department of Pharmacology and Biomedical Sciences, Seoul National University College of Medicine, Seoul, Republic of Korea

WS02-26-P

Selective expansion of tumor-antigen specific CD8 T cells with engineered exosome
1)
1, 2)
1)
1, 2)
〇 Xiabing Lyu , Tomoyoshi Yamano , Shota Imai , Rikinari Hanayama

1)

Department of Immunology, Graduate school of medicine, Kanazawa University, Kanazawa, Japan, 2)WPI Nano Life Science Institute, Kanazawa
University, Kanazawa, Japan
WS02-27-O/P

Innate immune components critical to the effect of oncolytic virus therapy with HSV-1〇 Shumpei Uchida , Tsukasa Seya , Shizuo Akira , Ryutaro Fukui , Kensuke Miyake , Tomoki Todo ,Norimitsu Kadowaki1)
1)

2)

3)

4)

4)

5)

1)

Division of Hematology, Faculty of Medicine, Kagawa Univ., Kagawa, Japan, 2)Nebuta Research Institute for Life Sciences, Aomori Univ.,
Aomori, Japan, 3)Immunology Frontier Research Center, Osaka Univ., Osaka, Japan, 4)Division of Infectious Genetics, Institute of Medical
Science, Univ. Tokyo, Tokyo, Japan, 5)Division of Innovative Cancer Therapy, Institute of Medical Science, Univ. Tokyo, Tokyo, Japan
WS02-28-P

Enzyme-driven de-glycosylation improves antigens recognition〇 Chih-Yu Lin, Shih-Yu Chen
Institute of Biomedical Science, Academia Sinica, Taipei, Taiwan

December 7
WS03

Infection and Immunity I

WS03-01-O/P

 orphyromnas gingivalis infection triggers enhancement of severity for EAE following inflammasomeP
activation in macrophages〇 Tokuju Okano, Toshihiko Suzuki
Graduate School of Medical and Dental Sciences Tokyo Medical and Dental University (TMDU)

WS03-02-O/P

The effects of malaria on bone marrow hematopoietic stem cell niches
1, 2)
1)
1)
2, 3)
1, 2)
〇 Michelle Sue Jann Lee , Julia Matsuo-Dapaah , Camila Del Rosario Zorrilla , Ken J. Ishii , Cevayir Coban

1)
Division of Malaria Immunology, Institute of Medical Science, The University of Tokyo, Japan, 2)International Vaccine Design Center (VDesC),
The Institute of Medical Science, The University of Tokyo, Japan, 3)Division of Vaccine Science, Institute of Medical Science, The University ofTokyo, Japan

WS03-03-O/P

IFN-γ induced GTPases・GBPchr5 play an important role for anti-Toxoplasma host defense〇 Ayumi Kuratani , Masahiro Yamamoto
1)

1, 2, 3)

1)

Department of Immunoparasitology, RIMD, Osaka University, 2)Laboratory of Immunoparasitology, IFReC, Osaka University, 3)CIDER, Osaka
University
WS03-04-O/P

LILRB3 and LILRA6 recognize bacteria in an allele-specific manner〇 Gen Hasegawa , Kouyuki Hirayasu
Rikinari Hanayama1, 2, 3, 8)
1)

1, 2, 3)

, Yifan Li3), Hisashi Arase4, 5), Masaya Yamaguchi6), Shigetada Kawabata7),

1)

Department of Immunology, Graduate School of Medical Sciences, Kanazawa University, Ishikawa, Japan, 2)Advanced Preventive Medical
Sciences Research Center, Kanazawa University, Ishikawa, Japan, 3)Department of Immunology, Graduate School of Advanced Preventive
Medical Sciences, Kanazawa University, Ishikawa, Japan, 4)Department of Immunochemistry, Research Institute for Microbial Diseases, Osaka
University, Osaka, Japan, 5)Laboratory of Immunochemistry, Immunology Frontier Research Center, Osaka University, Osaka, Japan,
6)
Bioinformatics Unit, Graduate School of Dentistry, Osaka University, Osaka, Japan, 7)Department of Oral and Molecular Microbiology, Graduate
School of Dentistry, Osaka University, Osaka, Japan, 8)WPI Nano Life Science Institute (NanoLSI), Kanazawa University, Ishikawa, Japan
WS03-05-O/P

A novel role of GRIM-19 in cytokine production in macrophages upon mycobacterial infection〇 Giichi Takaesu

1, 2, 3), Tomomi Kurane2), Masayuki Umemura1, 2, 3), Goro Matsuzaki1, 2, 3)

1)

Tropical Biosphere Research Center, University of the Ryukyus, 2)Department of Host Defense, Graduate School of Medicine, University of the
Ryukyus, 3)Advanced Medical Research Center, Faculty of Medicine, University of the Ryukyus

91

WS03-06-O/P

	The intracellular pathogen Francisella tularensis escapes from adaptive immunity by metabolic
adaptation〇 Kensuke Shibata
Masahisa Watarai4)

1, 2, 3)

, Takashi Shimizu4), Emi Ito2), Francois Legoux5), Sho Yamasaki2, 6, 7, 8), Olivier Lantz5),

1)
Department of Microbiology and Immunology, Yamaguchi University Graduate School of Medicine, Ube, Japan, 2)Department of Molecular
Immunology, Research Institute for Microbial Diseases, Osaka University, Suita, Japan, 3)Department of Ophthalmology, Graduate School of
Medical Sciences, Kyushu University, 4)Joint Faculty of Veterinary Medicine, Laboratory of Veterinary Public Health, Yamaguchi University,
Ube, Japan, 5)INSERM U932, PSL University, Institut Curie, Paris, France; Laboratoire d'immunologie clinique, Institut Curie, Paris, France;
Centre d'investigation Clinique en Biothérapie, Institut Curie (CIC-BT1428), Paris, France, 6)Laboratory of Molecular Immunology, Immunology
Frontier Research Center, Osaka University, Suita, Japan, 7)Division of Molecular Design, Medical Institute of Bioregulation, Kyushu University,
Fukuoka, Japan, 8)Division of Molecular Immunology, Medical Mycology Research Center, Chiba University, Chiba , Japan

WS03-07-O/P

	Immunological mechanism for reactivated cryptococcosis in persistently infected mice after treatment
with FTY720
1)
2)
2)
3)
2, 4)
4)
〇 Michiko Yoshida , Nana Nakahata , Takeshi Shinomiya , Hayato Sato , Ko Sato , Jun Kasamatsu ,
5)
5)
2)
2)
Hiromasa Tanno , Emi Kanno , Keiko Ishii , Kazuyoshi Kawakami
1)
Department of Pediatrics, Tohoku University Graduate School of Medicine, Sendai, Miyagi, Japan, 2)Department of Medical Microbiology,
Mycology and Immunology, Tohoku University Graduate School of Medicine, Sendai, Miyagi, Japan, 3)Department of Plastic and Reconstructive
Surgery, Tohoku University Graduate School of Medicine, Sendai, Miyagi, Japan, 4)Department of Intelligent Network for Infection Control,
Tohoku University Graduate School of Medicine, Sendai, Miyagi, Japan, 5)Department of Translational Science for Nursing, Tohoku University
Graduate School of Medicine, Sendai, Miyagi, Japan

WS03-08-O/P

Immune activating receptors specific for variant surface antigens of Plasmodium falciparum〇 Akihito Sakoguchi , Samuel Chamberlain , Matthew Higgins , Shiroh Iwanaga , Hisashi Arase
1)

2)

2)

1)

3, 4, 5)1)

2)

Department of Molecular Protozoology, Research Institute for Microbial Diseases, Osaka University, Osaka, Japan, Department ofBiochemistry, University of Oxford, Oxford, UK, 3)Department of Immunochemistry, Research Institute for Microbial Diseases, Osaka University,
Osaka, Japan, 4)Laboratory of Immunochemistry, WPI Immunology Frontier Research Center, Osaka University, Osaka, Japan, 5)Center for
Infectious Disease Education and Research, Osaka University, Osaka, Japan
WS03-09-O/P

Dermanyssus gallinae suppressively modulate host immune responses during infestation
1, 2)
2, 3)
2)
4)
4)
4)
〇 Sotaro Fujisawa , Shiro Murata , Masayoshi Isezaki , Takumi Sato , Eiji Oishi , Akira Taneno ,
3)
3)
2, 3)
2, 3, 5)
Naoya Maekawa , Tomohiro Okagawa , Satoru Konnai , Kazuhiko Ohashi
1)

Department of Molecular Genetics, Graduate School of Medical Science, Kanazawa University, 2)Department of Disease Control, Faculty of
Veterinary Medicine, Hokkaido University, 3)Department of Advanced Pharmaceutics, Faculty of Veterinary Medicine, Hokkaido University,
4)
Vaxxinova Japan K.K., 5)International Affairs Office, Faculty of Veterinary Medicine, Hokkaido University
WS03-10-P

Prophylactic Effect of Ivermectin on SARS-CoV-2 Induced Disease in a Syrian Hamster Model〇 Takayuki Uematsu , Tomomi Takano , Anna Kitajima , Hidehito Matsui , Noritada Kobayashi , Hideaki Hanaki
1)

2)

1)

3)

1)

1)

3)

2)

Biomedical Laboratory, Division of Biomedical Research, Kitasato University Medical Center, Saitama, Japan., Laboratory of Veterinary
Infectious Disease, Department of Veterinary Medicine, Kitasato University, Towada, Japan., 3)Infection Control Research Center, Ōmura Satoshi
Memorial Institute, Kitasato University, Tokyo, Japan
WS03-11-P

A single immunization with cellular vaccine provides the dual protection against SARS-CoV-2 and cancer〇 Shogo Ueda, Shin-Ichiro Fujii, Kanako Shimizu
RIKEN, IMS

WS03-12-P

Molecular mechanism of enhanced infectivity by SARS-CoV-2 Omicron
1, 2)
1, 2)
1, 2)
1, 2)
1, 2)
〇 Shuhei Higuchi , Liu Yafei , Wataru Nakai , Masako Kohyama , Hisashi Arase

1)
Laboratory of Immunochemistry, WPI Immunology Frontier Research Center, Osaka University, 2)Department of Immunochemistry, ResearchInstitute for Microbial Diseases, Osaka University

WS03-13-P

	Zika virus induces pathogenic T cell-attracting chemokines in the central nervous system and exacerbates
experimental autoimmune encephalomyelitis〇 Naganori Kamiyama, Thanyakorn Chalalai, Sotaro Ozaka, Shimpei Ariki, Yomei Kagoshima, Nozomi Sachi,
Takashi Kobayashi
Department of Infectious Disease Control, Faculty of Medicine, Oita University, Oita, Japan92

WS03-14-P

Analysis of immune responses in a murine oral candidiasis model
1)
1)
1, 2)
1)
1)
1)
〇 Kenji Toyonaga , Emi Kaji , Jun-Ichi Nagao , Sonoko Tasaki , Sari Kishikawa , Kanae Negoro-Yasumatsu ,1, 2)
Yoshihiko Tanaka
1)Section of Infection Biology, Department of Functional Bioscience, Fukuoka Dental College, Fukuoka, Japan, 2)Oral Medicine Research Center,
Fukuoka Dental College, Fukuoka, Japan
WS03-15-P

The effect of LPS preconditioning on the Plasmodium berghei ANKA blood stage infection〇 Takeshi Ono , Yoko Yamaguchi , Manabu Kinoshita
1)

1)

2)

1)

Department of Global Infectious Diseases and Tropical Medicine, National Defense Medical College, Saitama, Japan, 2)Department of
Immunology and Microbiology, National Defense Medical College, Tokorozawa, Japan
WS03-16-P

Investigation of Th17-cell mediated immune response against the pathogenic fungus Candida albicans
1, 2)
1)
1)
1, 3)
1)
2)
1, 3)
〇 Emi Kaji , Kenji Toyonaga , Sonoko Tasaki , Jun-Ichi Nagao , Sari Kishikawa , Mizuko Ikeda , Yosihiko Tanaka

1)Section of Infection Biology, Department of Functional Bioscience, Fukuoka Dental College, Fukuoka, Japan, 2)Department of Anaesthesia
Management, Fukuoka Dental College, Fukuoka, Japan, 3)Oral Medicine Research Center., Fukuoka Dental College, Fukuoka, Japan
WS03-17-P

Role of thymic stromal lymphopoietin in the protection against Strongyloides venezuelensis infection〇 Koubun Yasuda , Atsuhide Koida , Takumi Adachi , Kazufumi Matsushita , Etsushi Kuroda
1)

2)

1)

1)

1)

1)

2)

Department of Immunology, Hyogo Medical University, Hyogo, Japan, Department of Otolaryngology–Head and Neck Surgery, Kyoto
Prefectural University of Medicine, Kyoto, Japan

WS03-18-P

	The alteration of intestinal microbiota, short chain fatty acids receptors and type 2 immune responses
against gastrointestinal nematode parasite in aged mice
〇 Motoko Morimoto , Wakako Ikeda-Ohtsubo

2)

1)

1)

2)

School of Food Industrial Sciences, Miyagi University, Graduate School of Agricultural Sciences, Tohoku University

WS03-19-P

Antibiotics enhance the bacterial evasion from host immunity〇 Uki Kimura , Saiki Karen , Nobuhiro Matsuyama , Akiko Takaya , Koji Tokoyoda
1)

1)

1)

2)

1)

1)

Division of Immunology, School of Life Science, Faculty of Medicine, Tottori University, Yonago, Japan., 2)Department of Natural Products
Chemistry, Graduate School of Pharmaceutical Sciences, Chiba University, Chiba, Japan.
WS03-20-P

The evaluation of a novel tuberculosis vaccine with cynomolgus monkeys〇 Natsuko Yamakawa, Yasuhiro Yasutomi
Tsukuba Primate Research Center, National Institutes of Biomedical Innovation, Health and Nutrition (NIBIOHN), Ibaraki, Japan

WS03-21-P

WS03-22-P

Withdrawn	Cervical lymph node-derived CXCR3+ regulatory T cells alleviate anxiety-like behavior via attenuation ofsepsis-associated encephalopathy in the septic mouse model〇 Masafumi Saito , Yuko Ono , Kyosuke Agawa , Kimihiro Yamashita , Joji Kotani
1)

1)

2)

2)

1)

1)

Division of Disaster and Emergency and Critical Care Medicine, Kobe University Graduate School of Medicine, 2)Division of Gastrointestinal
Surgery, Department of Surgery, Kobe University Graduate School of Medicine
WS03-23-P

Development of periodontitis mediated by T-cell immune response against periodontal bacteria〇 Jun-Ichi Nagao , Sari Kishikawa , Kenji Toyonaga , Emi Kaji , Kanae Negoro-Yasumatsu , Sonoko Tasaki ,Yoshihiko Tanaka1, 2)
1, 2)

1)

1)

1)

1)

1)

1)
Section of Infection Biology, Department of Functional Bioscience, Fukuoka Dental Collage, 2)Oral Medicine Research Center, Fukuoka Dental
College93

WS03-24-P

	Distinct roles of IL-27 produced by innate cells in shaping the immune response against Plasmodium
parasite〇 Ganchimeg Bayarsaikhan , Shin-Ichi Inoue , Kazumi Kimura , Hiroki Yoshida , Masahiro Yamamoto ,Katsuyuki Yui1, 4)
1)

1)

1)

2)

3)

1)
Division of Immunology, Department of Molecular Microbiology and Immunology, Graduate School of Biomedical Sciences, Nagasaki
University, Nagasaki, Japan, 2)Division of Molecular and Cellular Immunoscience, Department of Biomolecular Science, Faculty of Medicine,
Saga University, Saga, Japan, 3)Laboratory of Immunoparasitology, WPI Immunology Frontier Research Center, Osaka University, Osaka, Japan,
4)
Institute of Tropical Medicine, Nagasaki University, Nagasaki Japan

WS03-25-P	Improvement of post-exercise immune compromise by consumption of probiotic mix of 30 strains ofbacteria〇 Rintaro Fujikawa, Tatsunori Mori, Keita Suzuki
AuB Ltd. Tokyo, Japan

WS03-26-P

	Interleukin-17A released from intestinal γδT cells induces cytokine storm in mice with severe dengue〇 Takeshi Kurosu , Daisuke Okuzaki , Masaaki Murakami
1)

2)

1)

3)

2)

National Institute of Infectious Diseases, WPI Immunology Research Center, Osaka University, 3)Institute for Genetic Medicine and Graduate
School of Medicine, Hokkaido University

December 7
WS04

Dendritic cells and macrophages-1: Immune regulation and disease perspectives

WS04-01-O/P

Dendritic cells regulate peripheral T cell survival through the CD47-SIRPα signaling
1)
1, 2)
1)
1)
1, 2)
1)
〇 Yasuyuki Saito , Satomi Komori , Hiroki Yoshida , Risa Sugihara , Tomoko Takai , Takenori Kotani ,1)
1, 2)
Yoji Murata , Takashi Matozaki
1)
Division of Molecular and Cellular Signaling, Department of Biochemistry and Molecular Biology, Kobe University Graduate School of
Medicine, Kobe, Japan, 2)Division of Biosignal Regulation, Department of Biochemistry and Molecular Biology, Kobe University Graduate
School of Medicine, Kobe, Japan

WS04-02-P

Identification of E3 ligase for CIITA〇 Yusuke Kasuga , Masashi Watanabe , Ryota Ouda , Shigetsugu Hatakeyama , Koich Kobayashi
1)

2)

1)

2)

1)

1)

2)

Department of Immunology, Hokkaido University Graduate School of Medicine, Sapporo, Hokkaido, Japan, Department of Medical Chemistry,
Hokkaido University Graduate School of Medicine, Sapporo, Hokkaido, Japan
WS04-03-O/P

Characterization of tissue macrophages involved in the pathogenesis of type I interferonopathy〇 Taku Sato , Toshiaki Ohteki , Takeshi Namiki
1)

1)

2)

1)

Department of Biodefense Research, Medical Research Institute, Tokyo Medical and Dental University (TMDU), Tokyo, Japan, 2)Department of
Dermatology, Graduate School of Medical and Dental Sciences, Tokyo Medical and Dental University (TMDU), Tokyo, Japan
WS04-04-O/P

Palladium-induced association of inter-MHC class I is involved in development of metal allergy〇 Koyu Ito , Masato Kosuge , Yuri Takeda , Kouetsu Ogasawara
1)

1)

2)

1)

1)

Department of Immunobiology, Institute of Development, Aging, and Cancer, Tohoku University, 2)Division of Oral and Maxillofacial Surgery,
Department of Disease Management Dentistry, Tohoku University Graduate School of DentistryWS04-05-P

DC have dual function of T cell stimulation and suppression for presented each antigen
1, 2)
1, 3)
1)
3)
2)
〇 Yoshihiro Oya , Tadamichi Kasuya , Ryutato Matsumura , Hiroshi Nakajima , Ethan Shevach
1)

National Hospital Organization Chibahigashi National Hospital, Chiba, Japan, 2)National Institute of Allergy and Infectious Diseases, National
Institutes of Health, MD, U.S.A, 3)Graduate School of Medicine, Chiba University, Chiba, Japan
WS04-06-O/P

Endosomal abnormalities in dendritic cells cause autoimmune liver diseases〇 Shin-Ichiroh Saitoh , Kenichi Harada , Yoshiko Mori-Saitoh , Ge-Hong Sun-Wada , Tamami Denda ,Yasunori Ota4), Hiroshi Sagara5), Yuji Watanabe5), Yoh Wada6), Kensuke Miyake1, 7)
1)

2)

1)

1)

3)

4)

Division of Infectious Genetics, Department of Microbiology and Immunology, The Institute of Medical Science, The University of Tokyo,
Japan, 2)Department of Human Pathology, Kanazawa University School of Medicine, Kanazawa, Japan., 3)Department of Biochemistry, Facultyof Pharmaceutical Sciences, Doshisha Women's College, Kohdo, Kyotanabe, Kyoto, Japan., 4)Department of Pathology, Research Hospital,The
Institute of Medical Science, The University of Tokyo, Tokyo, Japan., 5)Medical Proteomics Laboratory, The Institute of Medical Science, The
University of Tokyo, Tokyo, Japan., 6)Division of Biological Science, Institute of Scientific and Industrial Research, Osaka University, Ibaraki,
Osaka, Japan., 7)Laboratory of Innate Immunity, The Institute of Medical Science, The University of Tokyo, Tokyo, Japan94

WS04-07-P

	The gut microbial metabolite 10-oxo-cis-6,trans-11-octadecadienoic acid ameliorates colitis in mice withactivating the NRF2 pathway in dendritic cells〇 Miki Ando , Kazuki Nagata , Naoki Kodama , Takuya Yashiro , Naoto Ito , Gaku Ichihara , Masayuki Yamamoto ,Shigenobu Kishino4), Jun Ogawa4), Chiharu Nishiyama1)
1)

1)

1)

1)

1)

2)

3)

1)
Department of Biological Science and Technology, Tokyo University of Science, Tokyo, Japan, 2)Department of Occupational and Environmental
Health, Tokyo University of Science, Tokyo, Japan, 3)Department of Medical Biochemistry, Tohoku University Graduate School of Medicine,
Miyagi, Japan, 4)Division of Applied Life Sciences, Graduate School of Agriculture, Kyoto University, Kyoto, Japan

WS04-08-O/P	Exposure to Multi-Wall Carbon Nanotubes Promotes Fibrous Proliferation by Production of Matrix
Metalloproteiase-12 via NF-κB Activation in Chronic Peritonitis〇 Takaaki Tsunematsu, Rieko Arakaki, Mami Sato, Kunihiro Otsuka, Naozumi Ishimaru
Department of Oral Molecular Pathology, Tokushima University Graduate School of Biomedical Sciences

WS04-09-P

Dendritic cell-mediated selective induction of memory CD8+ T cell subsets〇 Momo Kamei , Kazuhiko Matsuo , Shiki Takamura , Takashi Nakayama
1)

1)

2)

1)

1)

2)

Division of Chemotherapy, Kindai University Faculty of Pharmacy, Department of Immunology, Kindai University Faculty of Medicine

WS04-10-P

A new approach to analysis of phagocytosis using CellProfiler〇 Akito Hattori , Kana Onodera , Riko Hidai , Manami Shizu , Miho Shimizu , Yuki Nishigai , Mizuki Hirahara ,Saori Fukuda2), Kazuya Iwabuchi1), Hideyuki Okano3), Etsuro Ohta2, 3, 4, 5)
1)

2)

1)

2)

2)

2)

2)

1)
Program in Cellular Immunology, Graduate School of Medical Science, Kitasato University, Kangawa, Japan, 2)Department of Immunology II,
Kitasato University School of Allied Health Sciences, Kanagawa, Japan, 3)Department of Physiology, Keio University School Medicine, Tokyo,
Japan, 4)R&D center for Cell Design, Institute for Regenerative Medicine and Cell Design, Kitasato University, Kanagawa, Japan, 5)Division ofClinical Immunology, Graduate School of Medical Sciences, Kitasato University, Kanagawa, Japan

WS04-11-O/P

	A study of the effect of high-fat diet intake on microglia functional activity in APP NL-G-F/NL-G-F Alzheimer's
disease model mice
〇 Shuhan Yang, Hirofumi Miyazaki, Yuji Owada
Department of Organ Anatomy, Graduate School of Medicine, Tohoku University, Sendai, Japan

WS04-12-P

Endocytosis of amyloid β42 (Aβ) in differentiated microglia like cells can be interrupted by IKK inhibitor〇 Duo Wang, Yasuhiro Yoshida

University of Occupational and Environmental Health, Japan
WS04-13-O/P

Progesterone prevents murine miscarriage by suppressing the immunostimulatory activity of macrophage
1, 2)
1, 2)
1, 2)
1)
3)
2)
1)
〇 Yasuyuki Negishi , Hajime Ino , Yumi Horii , Eri Koike , Yoshio Shima , Shunji Suzuki , Rimpei Morita

1)
Department of Microbiology and Immunology, Nippon Medical School, Tokyo, Japan, 2)Department of Obstetrics and Gynecology, Nippon
Medical School, Tokyo, Japan, 3)Department of Pediatrics, Nippon Medical School Musashikosugi Hospital, Kanagawa, Japan

WS04-14-P

Multifaceted role of an atypical cyclin protein in regulating inflammation〇 Yee Kien Chong , Sarang Tartey , Osamu Takeuchi
1)

2)

1)

1)

Department of Medical Chemistry, Graduate School of Medicine, Kyoto University, Kyoto, Japan., 2)IBM Biosciences Inc, Mountain View,
California, US
WS04-15-P

Mass spectrometric identification of tryptophan nitration sites on proteins in M1-polarized macrophages〇 Eri Shimura , Ayako Shigenaga , Aiki Murayama , Tomoya Nakagawa , Ryo Ishihara , Takeshi Baba ,Fumiyuki Yamakura3)
1)

2)

1)

1)

1)

1)

1)
Faculty of Medicine, Juntendo University, 2)Institute of Health and Sports Science & Medicine, Juntendo University, 3)Faculty of Health Science,
Juntendo University

WS04-16-O/P	Intranasal administration of ceramide liposomes inhibits ragweed pollen-induced allergic rhinitis bytargeting CD300f
1)
1, 2)
1)
1)
1)
1, 3)
1, 4)
〇 Ayako Kaitani , Takuma Ide , Kumi Izawa , Tomoaki Ando , Akie Maehara , Lisa Yamamoto , Yasuharu Kume ,
1, 5)
1, 5)
1)
1)
1)
Hexing Wang , Koji Tokushige , Nobuhiro Nakano , Ko Okumura , Jiro Kitaura
1)
Atopy (Allergy) Research Center, Juntendo University Graduate School of Medicine, 2)Department of Otorhinolaryngology, Juntendo University
Graduate School of Medicine, 3)Juntendo University School of Medicine (5th year medical student), 4)Department of Ophthalmology, Juntendo
University Urayasu Hospital, 5)Department of Science of Allergy and Inflammation95

WS04-17-P

	Polycomb Repressive Complex 2 Epigenetically Regulates Pro-inflammatory Responses in
Lipopolysaccharide-tolerant macrophages
1, 2)
2, 3)
2, 4)
1, 2)
〇 Atsadang Boonmee , Salisa Benjaskulluecha , Patipark Kueanjinda , Benjawan Wongprom ,
1, 2)
5)
5)
1, 2, 3)
Thitiporn Pattarakankul , Junichiro Takano , Haruhiko Koseki , Tanapat Palaga
1)
Department of Microbiology, Faculty of Science, Chulalongkorn University, Bangkok, Thailand, 2)Center of Excellence in Immunology and
Immune-mediated Diseases, Chulalongkorn University, Bangkok Thailand, 3)Inter-disciplinary Graduate Program in Medical Microbiology,
Graduate School, Chulalongkorn University, Bangkok, Thailand, 4)Department of Microbiology, Faculty of Medicine, Chulalongkorn University,
Bangkok, Thailand, 5)Laboratory for Developmental Genetics, RIKEN Center for Integrative Medical Sciences, Yokohama, Japan

Analysis of physiological function of mutant LRRK2-expressing microglia

WS04-18-P〇 Riko Hidai , Akito Hattori , Kana Onodera , Manami Shizu , Miho Shimizu , Yuki Nishigai , Mizuki Hirahara ,Saori Fukuda2), Masashi Sato1), Kazuya Iwabuchi1), Etsuro Ohta2, 3, 4)
1)

1)

2)

2)

2)

2)

2)

1)
Program in Cellular Immunology, Graduate School of Medical Science, Kitasato University, 2)Department of Immunology II, Kitasato University
School of Allied Health Sciences, 3)R&D center for Cell Design, Institute for Regenerative Medicine and Cell Design, Kitasato University,
4)
Division of Clinical Immunology, Graduate School of Medical Sciences, Kitasato University

WS04-19-P

	Lipopolysaccharide pre-conditioning upregulates renal macrophage function and ameliorates acutekidney injury associated with Staphylococcus aureus bacteremia
1)
2)
1, 3)
1)
2)
2)
2)
〇 Keiko Tanoue , Hiroyuki Nakashima , Seigo Ito , Hiroyasu Goto , Kazuma Mori , Kazuki Koiwai , Azusa Kato ,2)
1)2)
Masahiro Nakashima , Naoki Oshima , Manabu Kinoshita
1)
Department of Nephrology and Endocrinology, National Defense Medical College, Saitama, Japan, 2)Department of Immunology andMicrobiology, National Defense Medical College, Saitama, Japan, 3)Department of Internal Medicine, Self-Defence Force Iruma Hospital,
Saitama, Japan

WS04-20-P

	Unique cell harvesting technology without trypsinization -Evaluation of surface protein quantity andcytokine production level in mouse macrophage collected by temperature-response cultureware UpCell®〇 Eriko Ikeda, Asumi Yoshihara, Yuzo Kasuya
Cultureware Development Department, CellSeed inc., Tokyo, Japan

WS04-21-P

Elucidation of the pathogenesis of NASH by intravital imaging technology〇 Junichi Kikuta, Sayaka Ishida, Masaru Ishii
Department of Immunology and Cell Biology, Graduate School of Medicine and Frontier Biosciences, Osaka University, Osaka, Japan

December 7
WS05

Innate lymphocytes

WS05-01-O/P

Self-antigen for mucosal-associated invariant T (MAIT) cells
1, 2)
1, 2)
1, 2)
3)
1, 2)
1, 2)
〇 Emi Ito , Ami Takeyama , Shotaro Mori , Kensuke Shibata , Eri Ishikawa , Masamichi Nagae ,1, 2)
Sho Yamasaki
1)
Department of Molecular Immunology, Research Institute for Microbial Diseases, Osaka University, Suita, Japan, 2)Immunology Frontier
Research Center, Osaka University, Suita, Japan, 3)Department of Microbiology and Immunology, Graduate School of Medicine, Yamaguchi
University, Ube, Japan

WS05-02-P

MR1 deficiency enhances IL-17 immune responses in allergic contact dermatitis〇 Masashi Satoh, Chizuru Oowa, Kazuya Iwabuchi
Department of Immunology, Kitasato University School of Medicine, Sagamihara, Japan

WS05-03-O/P

Elucidation of the role of C1orfX in natural killer cells
1, 2)
1, 3, 4)
, Akira Shibuya1, 3, 4)〇 Elfira Amalia Deborah , Tsukasa Nabekura

1)
Department of Immunology, Faculty of Medicine, University of Tsukuba, Japan, 2)Doctoral Program in Medical Science, Graduate School ofComprehensive Human Sciences, University of Tsukuba, Japan, 3)Life Science Center for Survival Dynamics, Tsukuba Advanced Research
Alliance (TARA), University of Tsukuba, Japan, 4)R&D Center for Innovative Drug Discovery, University of Tsukuba, Japan

WS05-04-P

Role of homeostatic MHC class I recognition in regulating the function of mature tissue-resident NK cells
1)
1)
1)
2, 3)
1)
〇 Ka He , Yui Yamamae , So-Ichiro Sasaki , Hideaki Tahara , Yoshihiro Hayakawa

1)
Section of Host Defences, Institute of Natural Medicine, University of Toyama, Toyama, Japan, 2)Project Division of Cancer Biomolecular
Therapy, Institute of Medical Science, The University of Tokyo, Tokyo, Japan, 3)Department of Cancer Drug Discovery and Development, Osaka
International Cancer Center, Osaka, Japan96

WS05-05-O/P

Caloric restriction induces cellular quiescence in hepatic ILC1s〇 Megumi Tatematsu , Akane Fuchimukai , Shunsuke Takasuga , Tsukasa Nabekura , Akira Shibuya ,Takashi Ebihara1)
1)

1)

1)

2)

2)

1)

Department of Medical Biology, Akita University Graduate School of Medicine, 2)Department of Immunology, Faculty of Medicine, and Center
for TARA, University of Tsukuba
WS05-06-O/P

Anatomic and functional compartmentalization of ILC2s in the small intestine〇 Satoshi Koga , Victor S Cortez , Claire E O’Leary , Hong-Erh Liang , Richard M Locksley
1)

1)

1)

1)

1)

1, 2, 3)2)

Department of Medicine, University of California San Francisco, San Francisco, California, U.S.A., Department of Microbiology &Immunology, University of California San Francisco, San Francisco, California, U.S.A., 3)Howard Hughes Medical Institute, University ofCalifornia San Francisco, San Francisco, California, U.S.A.
WS05-07-O/P

ILC2-derived IL-13 contributes to endometriosis exacerbation
1, 2)
1)
1, 2, 3, 4)〇 Kentaro Kubota , Tsuyoshi Kiniwa , Kazuyo Moro
1)

Laboratory for Innate Immune Systems, RIKEN Center for Integrative Medical Sciences (IMS), Kanagawa, Japan, 2)Laboratory for Innate
Immune Systems, Department of Immunology and Microbiology, Osaka University Graduate School of Medicine, Osaka, Japan, 3)Laboratory
for Innate Immune Systems, Osaka University Immunology Frontier Research Center, Osaka, Japan, 4)Laboratory for Innate Immune Systems,
Department of Microbiology and Immunology, Osaka University Graduate School of Frontier Biosciences, Osaka, Japan
WS05-08-P

Low-dose LPS exposure suppresses ILC2-mediated airway inflammation via interstitial macrophages
1, 2)
2)
1, 2, 3, 4)〇 Naoto Fujioka , Tetsuro Kobayashi , Kazuyo Moro
1)

Laboratory For Innate Immune Systems, Department Of Immunology And Microbiology, Osaka University Graduate School Of Medicine,
Osaka, Japan, 2)Laboratory For Innate Immune Systems, RIKEN Center For Integrative Medical Sciences (IMS), Yokohama, Japan, 3)Laboratory
For Innate Immune Systems, Osaka University Immunology Frontier Research Center, Osaka, Japan, 4)Laboratory For Innate Immune Systems,
Department of Microbiology and Immunology, Osaka University Graduate School Of Frontier Biosciences, Osaka, Japan
WS05-09-P

Enrichment of type I interferon signalling in the colonic ILC2 during experimental colitis〇 Emi Irie, Junya Tsunoda, Kentaro Iwata, Yoshiaki Takada, Yohei Mikami, Takanori Kanai
Keio University School of Medicine, Tokyo, Japan

WS05-10-P

IL-33 attenuate renal fibrosis via group2 innate lymphoid cells
1)
1)
1, 2)
1)
1, 2)
〇 Ryuichi Nagashima , Hiroki Ishikawa , Yoshihiro Kuno , Chikara Kohda , Masayuki Iyoda

1)
Department of Microbiology and Immunology, Showa University School of Medicine, 2)Division of Nephrology, Department of Medicine,Showa University School of Medicine

WS05-11-O/P

Interleukin-27 supports metabolic adaptation of Natural killer T cells and effector responses
1, 2)
1, 3)
4)
3)
5)
4)
〇 Yasuhiro Kamii , Koji Hayashizaki , Toshio Kanno , Yoshimasa Takahashi , Toshiaki Ohteki , Yusuke Endo ,1, 3)
Yuki Kinjo
1)
Department of Bacteriology, The Jikei University School of Medicine, Tokyo, Japan, 2)Division of Respiratory Diseases, Department of Internal
Medicine, The Jikei University School of Medicine, Tokyo, Japan, 3)Research Center for Drug and Vaccine Development, National Institute of
Infectious Diseases, Tokyo, Japan, 4)Department of Frontier Research and Development, Laboratory of Medical Omics Research, Kazusa DNA
Research Institute, Chiba, Japan, 5)Department of Biodefense Research, Medical Research Institute, Tokyo Medical and Dental University (TMDU),Tokyo, Japan

WS05-12-P

The regulatory mechanism of NKT cell and macrophage in ConA-induced hepatitis〇 Chizuru Oowa, Masashi Satoh, Kazuya Iwabuchi
Department of Immunology, Kitasato University School of Medicine, Sagamihara, Japan

WS05-13-P

Polycomb group gene Eed is required for invariant NKT development and maturation〇 Yun Guo, Masamoto Kanno, Tomoharu Yasuda
Department of Immunology, Graduate School of Biomedical & Health Sciences, Hiroshima University, Hiroshima, Japan

WS05-14-O/P

	CD96 blockade ameliorates imiquimod-induced psoriasis-like dermatitis via suppression of IL-17A
production by dermal gdT cells〇 Kyoko Oh-Oka , Fumie Abe , Akira Shibuya
1)

2)

1, 3, 4)1)

, Kazuko Shibuya1, 3)

Department of Immunology, Faculty of Medicine, University of Tsukuba, 2)TNAX Biopharma Corporation, 3)R&D Center for Innovative Drug
Discovery, University of Tsukuba, 4)Life Science Center for Survival Dynamics, Tsukuba Advanced Research Alliance, University of Tsukuba

97

WS05-15-P

	Role of IL-21 receptor in IL-17-producing γδT cells in the onset of experimental autoimmune
encephalomyelitis〇 Junichi Ishikawa, Akira Suto, Takahiro Kageyama, Kazuyuki Meguro, Shigeru Tanaka, Taro Iwamoto, Arifumi Iwata,
Shunsuke Furuta, Kei Ikeda, Kotaro Suzuki, Hiroshi Nakajima
Department of Allergy and Clinical Immunology, Graduate School of Medicine, Chiba University, Chiba, Japan

WS05-16-O/P

Regulatory mechanism of RORγt expression in ILC3
〇 Takuma Fukui , Satoshi Kojo , Eriko Sumiya , Shinichi Koizumi , Shinichiro Sawa
1)

2)

1)

1)

1)

1)

Division of Mucosal Immunology, Medical Institute of Bioregulation, Kyushu University, Fukuoka, Japan, 2)Division of Immunology and Stemcell biology, Institute of Medical, Pharmaceutical and Health Sciences, Kanazawa University, Kanazawa, Japan
WS05-17-O/P

Aging alters landscape of pulmonary innate lymphoid cells
1, 2)
1)
3)
3)
3)
〇 Masato Asaoka , Tetsuro Kobayashi , Tommy Walter Terooatea , Jen-Chien Chang , Akiko Minoda ,Hiroki Kabata2), Kazuyo Moro1, 4, 5)
1)

Laboratory for Innate Immune systems, Center for Integrative Medical Sciences, RIKEN, 2)Division of Pulmonary Medicine, Department ofMedicine, Keio University School of Medicine, 3)Laboratory for Cellular Epigenomics, Center for Integrative Medical Sciences, RIKEN,
4)Laboratory for Innate Immune Systems, Department of Microbiology and Immunology, Graduate School of Medicine, Osaka University,
5)
Immunology Frontier Research Center, Osaka University
WS05-18-O/P	A Japanese traditional medicine, Daikenchuto, alleviates colitis by reshaping microbial profiles andenhancing group 3 innate lymphoid cells
1, 2)
1, 3)
1)
1, 2)
1, 2, 3)
〇 Naoko Satoh-Takayama , Zhengzheng Shi , Tadashi Takeuchi , Ritsu Nagata , Hiroshi Ohno
1)

Laboratory for Intestinal Ecosystem, RIKEN Center for Integrative Medical Sciences, Yokohama, Kanagawa, Japan, 2)Immunobiology Laboratory,
Graduate School of Medical Life Science, Yokohama City University, Yokohama, Kanagawa, Japan, 3)Laboratory for Immune Regulation,
Graduate School of Medical and Pharmaceutical Sciences, Chiba University, Chiba, Chiba, Japan
WS05-19-P

	Differences of cytokine secretion capacity and gene expression of ILC2s in asthma patients and healthy
volunteers
1)
1)
2)
1, 2, 3, 4), Mai Yamagishi5), Misato Irie1),〇 Hiroki Kabata , Rie Baba , Yoshitaka Shirasaki , Takashi Kamatani
1)
1)
1)
6, 7)
Masako Matsusaka , Katsunori Masaki , Jun Miyata , Kazuyo Moro , Sotaro Uemura2), Koichi Fukunaga1)
1)

Division of Pulmonary Medicine, Keio University School of Medicine, 2)The University of Tokyo, 3)Tokyo Medical and Dental University,
Tokyo Medical and Dental University Hospital, 5)Live Cell Diagnosis, 6)RIKEN Center for IMS, 7)Osaka University

4)

WS05-20-P

Analysis for induction mechanisms of peritonitis regulated by adipose tissue
1, 2)
1, 2)
2)
3)
2)
〇 Ritsu Nagata , Naoko Satoh-Takayama , Tommy Terooatea , Yuichi Akama , Akiko Minoda ,3)
1, 2, 4)
Motomu Shimaoka , Hiroshi Ohno
1)
Graduate School of Medical Life Science, Yokohama City University, Kanagawa, Japan, 2)RIKEN Center for Integrative Medical Sciences,
Kanagawa, Japan, 3)Department of Molecular Pathobiology and Cell Adhesion Biology, Mie University Graduate School of Medicine, Tsu, Mie,
4)
Laboratory for Immune Regulation, Graduate School of Medical and Pharmaceutical Sciences, Chiba University, Chiba, Japan

WS05-21-P

Protein phosphatase 2A regulates NK cell effector function through mTOR pathway〇 Yui Yamamae, Yoshihiro Hayakawa
Section of Host Defences, Institute of Natural Medicine, University of Toyama, Toyama, Japan

WS05-22-P

	Ablation of the intracellular immune checkpoint molecule CIS potentiates antitumor effects against
glioblastoma by unleashing the functions of NK cells derived from human peripheral blood
1, 2, 3)
, Ryosuke Maeoka1), Takayuki Morimoto1), Ryosuke Matsuda1), Fumihiko Nishimura1),〇 Tsutomu Nakazawa
1, 3)
Mitsutoshi Nakamura , Shuichi Yamada1), Ichiro Nakagawa1), Young-Soo Park1), Takahiro Tsujimura2, 3),
Hiroyuki Nakase1)
1)

Department Neurosurgery, Nara Medical University, 2)Grandsoul Research Institute for Immunology, 3)Clinic Grandsoul Nara98

December 7
WS06

Autoimmune diseases -Tissue specific-

WS06-01-O/P

Autoantigen-specific B cell-targeted single-cell RNA-seq indicates multiple roles of B cells in pemphigus
1, 2)
1, 3)
4)
1)
1)
〇 Jun Yamagami , Shohei Egami , Takashi Watanabe , Ayano Fukushima-Nomura , Hisashi Nomura ,
1)
4)
1, 3)
Hayato Takahashi , Osamu Ohara , Masayuki Amagai
1)
Department of Dermatology, Keio University School of Medicine, 2)Department of Dermatology, Tokyo Women’s Medical University, 3)Laboratory
for Skin Homeostasis, RIKEN Center for Integrative Medical Sciences, 4)Laboratory for integrative genomics, RIKEN Center for Integrative
Medical Sciences

WS06-02-O/P

Analysis of naïve B cell in neuromyelitis optica spectrum disorders
1)
1)
1)
1, 2)
2)
2)
〇 Shuhei Sano , Soichiro Yoshikawa , Daisuke Noto , Yasunobu Hoshino , Yuji Tomizawa , Kazumasa Yokoyama ,2)
1)
Nobutaka Hattori , Sachiko Miyake
1)

Department of Immunology, Juntendo university, Tokyo, Japan, 2)Department of neurology, Juntendo university, Tokyo, Japan

WS06-03-O/P	Roles of anti-glycolipid antibodies in different animal models of multiple sclerosis with distinct clinicalcourses
1)
1)
1, 2)
1)
3)
1)
〇 Fumitaka Sato , Yumina Nakamura , Kota Moriguchi , Ah-Mee Park , Motoi Kuwahara , Seiichi Omura ,
1)
1)
4)
1)
Sundar Khadka , Ijaz Ahmad , Susumu Kusunoki , Ikuo Tsunoda
1)
Department of Microbiology, Kindai University Faculty of Medicine, Osaka, Japan, 2)Department of Internal Medicine, Japan Self Defense
Forces Hanshin Hospital, Hyogo, Japan, 3)Department of Neurology, Kindai University Faculty of Medicine, Osaka, Japan, 4)Japan Community
Health care Organization (JCHO) Headquarters, Tokyo, Japan

WS06-04-O/P

	Progressive multiple sclerosis patient-derived gut bacterial strain accelerates neuronal inflammation via
intestinal Th17 cells〇 Daiki Takewaki , Wakiro Sato , Hiroaki Masuoka , Masahira Hattori , Wataru Suda , Takashi Yamamura
1)

1)

2)

1)

2)

2)

1)

2)

National Center of Neurology and Psychiatry, Kodaira, Japan, RIKEN, Yokohama, Japan

WS06-05-O/P	γδT17 cells in Peyer’s patches acquire the encephalitogenic phenotype through the activation bycommensals and exacerbates autoimmune encephalomyelitis〇 Seiga Komiyama , Daisuke Takahashi , Tsuneyasu Kaisho , Koji Hase
1)

2)

3)

2)

1)

2)

Division of Biochemistry, Graduate School of Pharmacy, Keio University, Tokyo, Japan, Division of Biochemistry, Faculty of Pharmacy, Keio
University, Tokyo, Japan, 3)Institute of Advanced Medicine, Wakayama Medical University, Wakayama, Japan
WS06-06-O/P

Gut microbiota regulated miRNA disturbs BBB integrity in EAE〇 Manu Mallahalli , Manu Mallahalli , Hirohiko Hohjoh , Wakiro Sato , Shinji Oki , Takashi Yamamura
1)

1)

2)

1)

1)

1)

1)

2)

Department of Immunology, National Institute of Neuroscience, NCNP, Tokyo, Japan., Department of Molecular Pharmacology, National
Institute of Neuroscience, NCNP, Tokyo, Japan.
WS06-07-O/P

The role of Dual-specificity phosphatase family in seronegative spondyloarthropathy〇 Ming-Han Chen
Division of Allergy- Immunology- Rheumatology, Department of Medicine, Taipei Veterans General Hospital, Taipei, Taiwan

WS06-08-O/P

Roles of Histone Deacetylases in Orbital Fibroblasts from Graves’ Ophthalmopathy Patients
1)
1)
2)
2)
3)
〇 Supanuch Ekronarongchai , Pimchanok Phankeaw , Chirayus Khawsang , Tanapat Palaga , Preamjit Saonanon ,Vannakorn Pruksakorn3), Nattiya Hirankarn4), P. Martin van Hagen4, 5, 6), Willem A. Dik5), Sita Virakul2)
1)

Medical Microbiology, Interdisciplinary Program, Graduate School, Chulalongkorn University, Bangkok, Thailand., 2)Department ofMicrobiology, Faculty of Science, Chulalongkorn University, Bangkok, Thailand., 3)Department of Ophthalmology, Faculty of Medicine,
Chulalongkorn University, Bangkok, Thailand., 4)Department of Microbiology, Faculty of Medicine, Center of Excellence in Immunology and
Immune Mediated Diseases, Chulalongkorn University, Bangkok, Thailand., 5)Laboratory Medical Immunology, Department of Immunology,
Erasmus MC, University Medical Center, Rotterdam, the Netherlands., 6)Division of Clinical Immunology, Department of Internal Medicine,
Erasmus MC, University Medical Center, Rotterdam, the Netherlands

99

WS06-09-P

	Low MICA transcription levels are associated with the risk of Graves’ disease: Mendelian randomization
study
1)
1)
2)
2)
2)
3)
1, 4)
〇 Yoichi Sutoh , Shohei Komaki , Taiki Yamaji , Shiori Nakano , Ryoko Katagiri , Norie Sawada , Hideki Ohmomo ,
1)
1)
1)
2, 3)
1, 4)
Tsuyoshi Hachiya , Yayoi Otsuka-Yamasaki , So Umekage , Motoki Iwasaki , Atsushi Shimizu
1)
Division of Biomedical Information Analysis, Iwate Tohoku Medical Megabank Organization, Disaster Reconstruction Center, Iwate Medical
University, 2)Division of Epidemiology, National Cancer Center Institute for Cancer Control, 3)Division of Cohort research, National Cancer
Center Institute for Cancer Control, 4)Biomedical Laboratory Sciences, Institute of Biomedical Sciences, Iwate Medical University

WS06-10-P

Roles of Histone Methyltransferases in Orbital Fibroblast in the pathogenesis of Graves’ Ophthalmopathy〇 Sita Virakul , Sopita Visamol , Tanapat Palaga , Preamjit Saonanon , Vannakorn Pruksakorn ,Nattiya Hirankarn4), P. Martin Van Hagen5, 6), Willem A. Dik5)
1)

2)

1)

3)

3)

1)

Department of Microbiology, Faculty of Science, Chulalongkorn University, Bangkok, Thailand, 2)Medical Microbiology, Interdisciplinary
Program, Graduate School, Chulalongkorn University, Bangkok, Thailand, 3)Department of Ophthalmology, Faculty of Medicine, Chulalongkorn
University, Bangkok, Thailand, 4)Center of Excellence in Immunology and Immune mediated Disease, Department of Microbiology, Facultyof Medicine, Chulalongkorn University, Bangkok, Thailand, 5)Department of Immunology, Laboratory Medical Immunology, Erasmus MC,
University Medical Center, Rotterdam, The Netherlands, 6)Department of Internal Medicine, Division of Clinical Immunology, Erasmus MC,
University Medical Center, Rotterdam, The Netherlands
WS06-11-P

Elastin as novel biomarkers of orbital fibroblasts from Graves’ Ophthalmopathy (GO)〇 Rajit Chompoowong , Jutamas Wongphoom , Nakarin Kitkumtorn , Tanapat Palaga , Preamjit Saonanon ,Vannakorn Pruksakorn5), Nattiya Hirankarn6), P. Martin Van Hagen6, 7, 8), Willem A. Dik7, 8), Sita Virakul4)
1)

2)

3)

4)

5)

1)

Medical Microbiology, Interdisciplinary Program, Graduate School, Chulalongkorn University, Bangkok, Thailand, 2)Department of Pathology,
King Chulalongkorn Memorial Hospital, Bangkok, Thailand, 3)Department of Oral Biology, Faculty of Dentistry, Mahidol University, Bangkok,
Thailand, 4)Department of Microbiology, Faculty of Science, Chulalongkorn University, Bangkok, Thailand, 5)Department of Ophthalmology,
Faculty of Medicine, Chulalongkorn University, Bangkok, Thailand, 6)Center of Excellence in Immunology and Immune Mediated Disease,
Department of Microbiology, Faculty of Medicine, Chulalongkorn University, Bangkok, Thailand, 7)Department of Immunology, Laboratory
Medical Immunology, Erasmus MC, University Medical Center, Rotterdam, The Netherlands, 8)Department of Internal Medicine, Division ofClinical Immunology, Erasmus MC, University Medical Center, Rotterdam, The Netherlands
WS06-12-P

The role of Clec1A in the development of experimental autoimmune encephalomyelitis〇 Xiao-Qi Ye, Yulia Makusheva, Soo-Hyun Chung, Ce Tang, Yoichiro Iwakura
Center for Animal Disease Models, Research Institute for Biomedical Sciences, Tokyo University of Science

WS06-13-P

Interferon-γ signaling in Treg cells is required for suppression of EAE〇 Masaaki Okamoto , Masahiro Yamamoto
1)

1, 2, 3)

1)

Department of Immunoparasitology, Research Institute for Microbial Diseases, Osaka University, 2)Laboratory of Immunoparasitology, WPI
Immunology Frontier Research Center, Osaka University, 3)Department of Immunoparasitology, Center for Infectious Disease Education andResearch, Osaka University
WS06-14-P

	AQP4 peptide immunization induces neurological disease with clinical features of neuromyelitis optica
spectrum disorder in mice
〇 Shota Miyake, Kenichi Serizawa, Yoshichika Katsura, Keigo Yorozu, Mitsue Kurasawa, Haruna Tomizawa-Shinohara,
Hideyuki Yasuno, Yoshihiro Matsumoto
Product Research Department, Chugai Pharmaceutical Co., Ltd, Kanagawa, Japan

WS06-15-P

Autoreactive lymphocytes are generated in draining lymph nodes〇 Wataru Okada, Sano Nagano, Kana Matsuo, Miya Yoshino, Koji Tokoyoda
Division of Immunology, School of Life Science, Faculty of Medicine, Tottori University, Yonago, Japan

WS06-16-P

WS06-17-P

Withdrawn
	Regulatory mechanism of up-regulation of IL-10 by the Ca2+-activated K+ channelinhibition in miceregulatory T cells〇 Miki Matsui, Kyoko Endo, Susumu Ohya
Department of Pharmacology, Graduate School of Medical Sciences, Nagoya City University, Nagoya, Japan

WS06-18-P

The protective effect of Limonite on streptozotocin-induced type 1 diabetes
1)
1, 2)
1)
1)
1, 2)
〇 Tomoko Ano , Taro Yasuma , Corina N. D'Alessandro-Gabazza , Valeria Fridman D'Alessandro , Chisa Inoue ,
1, 2)
1, 2)
1)
2)
2)
1)
Yuko Okano , Atsuro Takeshita , Masaaki Toda , Kota Nishihama , Yutaka Yano , Esteban C Gabazza
1)

Department of Immunology, Mie University Graduate School of Medicine, 2)Department of Diabetes and Endocrinology, Mie University
Graduate School of Medicine

100Single cell-RNA sequencing of T cells in Akita mouse developing experimental autoimmune uveitis

WS06-19-P〇 Yoshiaki Nishio , Kozo Harimoto , Tomohito Sato , Masataka Ito , Masaru Takeuchi
1)

1)

1)

2)

1)

1)

2)

Department of Ophthalmology, National Defense Medical Collage, Saitama, Japan, Department of Developmental Anatomy, National Defense
Medical Collage, Saitama, Japan

Relevance of the TRAb-IgM induced by Epstein-Barr virus reactivation to Graves’ disease

WS06-20-P〇 Keiko Nagata , Kazuhiko Hayashi , Takeshi Imamura
1)

2)

1)

1)

2)

Division of Pharmacology, Faculty of Medicine, Tottori University, Department of Pathology, Faculty of Medicine, Tottori University

Expression analysis of follicular helper T cells in multiple sclerosis relapses

WS06-21-P〇 Ayako Koguchi , Reiko Kawasaki , Daisuke Motooka , Kaori Sakuishi , Tatsushi Toda
1)

1)

2)

1)

3)

1)

2)

Department of Neurology, the University of Tokyo, Tokyo, Japan, NGS core facility, Genome Information Research Center, Research Institutefor Microbial Diseases, Osaka University, Osaka, Japan, 3)Department of Neurology, Teikyo University, Chiba Medical Center, Chiba, Japan

December 7
WS07

Mucosal-Skin Immunity

WS07-01-O/P	
Lactococcus lactis subsp. Cremoris C60 establishes anti-inflammatory intestinal environment by
increasing interleukin-10 producing CD4+ T cells〇 Noriko Tsuji

1, 2, 3), Suguru Saito2, 4), Toshio Maekawa1, 2)

1)

Microbiology/ Immune Homeostasis, Dept. Pathology and Microbiology, Nihon University School of Medicine, 2)Cellular and MolecularEngineering, Dept. Life Technology and Science, AIST, 3)Dept. Food Science, Jumonji University, 4)Dept. Dentistry, Faculty of Medicine andDentistry, University of Alberta
WS07-02-P

	Gut dysbiosis abrogates the establishment of oral tolerance through the dysregulation of the crosstalk
between CD103+ conventional dendritic cells and innate lymphoid cells in mesenteric lymph nodes〇 Tomohiro Fukaya, Tomofumi Uto, Moe Tominaga, Katsuaki Sato
Division of Immunology, Department of Infectious Diseases, Faculty of Medicine, University of Miyazaki

WS07-03-O/P

Withdrawn

WS07-04-O/P

Decoding Interactions between Environmental Small Molecules and Host Receptors in the Gut
1, 2)
1)
1, 2)
〇 Motohiko Kadoki , Daniel Graham , Ramnik Xavier
1)

Broad Institute, Massachusetts, USA, 2)Center for Computational and Integrative Biology, Massachusetts General Hospital, Massachusetts, USA

WS07-05-O/P	CARS2-dependent sulfur metabolism controls intestinal inflammation by suppressing CD4+ T cellproliferation〇 Shunichi Tayama, Takeshi Kawabe, Kyoga Hiraide, Jing Li, Ziying Yang, Kosuke Sato, Akihisa Kawajiri,
Yuko Okuyama, Naoto Ishii
Department of Microbiology and Immunology, Tohoku University Graduate School of Medicine, Miyagi, Japan

WS07-06-O/P

Deep profiling identifies a unique tissue resident CD4+ T-cell subset enriched in Crohn’s disease〇 Takehito Yokoi, Mari Murakami, Kiyoshi Takeda
Department of Microbiology and Immunology, Graduate School of Medicine, Osaka University, Osaka, Japan

WS07-07-O/P

Gut-resident innate lymphoid cells regulate lipid metabolism in response to malnutrition〇 Takuma Misawa, Shigeo Koyasu
Yokohama City, Kanagawa, Japan, RIKEN IMS Laboratory for Immune Cell Systems

WS07-08-P

	An Il23a-Venus reporter strain reveals the spatio-temporal regulation of IL-23-producing cDC2 subset in
gut-associated lymphoid tissues〇 Daiya Ohara, Hitomi Watanabe, Yusuke Takeuchi, Yoonha Lee, Mukoyama Hiroki, Gen Kondoh, Keiji Hirota
Institute for life and medical science, kyoto university, kyoto, japan

101

WS07-09-P

	Secretory leukocyte protease inhibitor ameliorates murine experimental colitis by protecting theintestinal epithelial barrier
1, 2)
1, 2)
1, 2)
1)
1)
〇 Sotaro Ozaka , Shimpei Ariki , Yomei Kagoshima , Naganori Kamiyama , Nozomi Sachi ,1)
1)
1)
Thanyakorn Chalalai , Astri Dewayani , Takashi Kobayashi
1)
Department of Infectious Disease Control, Faculty of Medicine, Oita University, Oita, Japan, 2)Department of Gastroenterology, Faculty of
Medicine, Oita University, Oita, Japan

WS07-10-P

Roles of IL5 on maintenance of intestinal homeostasis in Ncx KO mice
〇 Yoshio Katsumata

1, 2)

1)

Department of Pediatric Surgery, Graduate School of Medicine, Chiba University,Chiba, Japan, 2)Department of Biomedical Science, Graduate
School of Medicine, Chiba University, Chiba, Japan
WS07-11-P	Deubiquitinase OTUD3 prevents colitis by regulating microbiota-dependent STING activation in stromalcell
Bo Li1), 〇 Haruka Tani1, 2), Taiki Sakaguchi1), Hisako Kayama1, 2, 3), Kiyoshi Takeda1, 2, 4)

1)
Laboratory of Immune Regulation, Department of Microbiology and Immunology, Graduate School of Medicine, Osaka University, Suita, Osaka,
Japan, 2)WPI Immunology Frontier Research Center, Osaka University, Suita, Osaka, Japan., 3)Institute for Advanced Co-Creation Studies, Osaka
University, Suita, Osaka, Japan., 4)Integrated Frontier Research for Medical Science Division, Institute for Open and Transdisciplinary Research
Initiatives, Osaka University, Suita, Japan.

WS07-12-P

Plasmodium infection causes the dysfunction of gastrointestinal system
1, 2)
1, 3)
1, 4)
1, 3, 4)
〇 Mariko Kamioka , Julia Matsuo-Dapaah , Michelle Sue Jann Lee , Cevayir Coban
1)

Division of Malaria Immunology, Department of Microbiology and Immunology, Institute of Medical Science, University of Tokyo (IMSUT),JSPS Research Fellowship for Young Scientists, Japan Society for the Promotion of Science, 3)Graduate School of Medicine, University ofTokyo, 4)International Vaccine Design Center, Institute of Medical Science, University of Tokyo (IMSUT)
2)

WS07-13-P

Prip2 is required for the formation of gut-associated lymphoid tissue〇 Naoko Kiya , Shinichiro Sawa , Miho Matuda
1)

1)

2)

1)

Division of Mucosal Immunology, Research Center for Systems Immunology, Medical Institute of Bioregulation, Kyushu University.,
Laboratory of Molecular and Cellular Biochemistry, Division of Oral Biological Sciences, Kyushu University

2)

WS07-14-P

Analysis of fibroblasts that initiate iBALT formation during influenza virus infection〇 Shini-Ichi Koizumi , Eriko Sumiya , Satoshi Kojo , Natoto Noguchi , Shinichiro Sawa
1)

1)

2)

1)

1)

1)

2)

Division of mucosal immunology, Medical Institute of Bioregulation, Kyushu university, Division of immunology and stem cell biology,
Pharmaceutical and Health Sciences, Kanazawa university
WS07-15-O/P

Mode of action analysis of IL-33 as a mucosal adjuvant〇 Amane Mukai , Koubun Yasuda , Shiori Egashira , Takumi Adachi , Kazufumi Matsushita , Tomoaki Hoshino ,Etsushi Kuroda1)
1)

1)

1)

1)

1)

2)

1)

Department of Immunology, Hyogo Medical University, School of Medicine, 2)Division of Respirology, Neurology, and Rheumatology,
Department of Medicine, Kurume University School of Medicine
WS07-16-O/P

Skin-resident ILC1 promote barrier response against mechanical stress〇 Tetsuro Kobayashi , Aki Minoda , Kazuyo Moro
1)

2)

1)

1, 3, 4)Innate Immune Systems, IMS, RIKEN, Yokohama, Japan, Cellular Epigenomics, IMS, RIKEN, Yokohama, Japan, 3)Innate Immune Systems,
Osaka University Graduate School of Medicine, Osaka, Japan, 4)Innate Immune Systems, Osaka University Immunology Frontier ResearchCenter, Osaka, Japan
WS07-17-O/P

2)

	M2 macrophages generated in the termination phase of skin allergic inflammation display highefferocytic capacity and promote resolution of inflammation〇 Kensuke Miyake , Junya Ito , Kazufusa Takahashi , Jun Nakabayashi , Shigeyuki Shichino , Hajime Karasuyama
1)

1)

1)

2)

3)

1)

1)

Inflammation, Infection and Immunity Laboratory, Advanced Research Institute, Tokyo Medical and Dental University (TMDU), Tokyo, Japan,
Institute of Education, Tokyo Medical and Dental University (TMDU), 3)Division of Molecular Regulation of Inflammatory and Immune Diseases,
Research Institute of Biomedical Sciences, Tokyo University of Science, Noda, Japan2)

WS07-18-P

Dermatitis and other inflammatory diseases induced by GATA3 mutations in T cells〇 Shoichiro Miyatake
Department of Immunology, Graduate School of Environmental Health Sciences, Azabu University, Kanagawa, Japan102

Role for skin sensory nerves in controlling inflammation in the mouse model of atopic dermatitis

WS07-19-P〇 Sonoko Takahashi, Takaharu Okada
RIKEN Center for Integrative Medical Sciences, Kanagawa, Japan
WS07-20-P	Lymphotoxin β receptor signaling mediates the formation of high endothelial venule-like vessels in
atopic dermatitis-like skin lesions in mice
1)
1)
1, 2)
1)
3)
1, 4)
〇 Shuto Kanameishi , Sachiko Ono , Yuki Honda Keith , Ryota Asahina , Tetsuya Honda , Kenji Kabashima

1)
Department of Dermatology, Graduate School of Medicine, Kyoto University, Kyoto, Japan, 2)Immunology Division, Garvan Institute of Medical
Research, Sydney, NSW, Australia, 3)Department of Dermatology, Hamamatsu University School of Medicine, Hamamatsu, Japan, 4)Singapore
Immunology Network (SIgN) and Skin Research Institute of Singapore, Agency for Science, Technology and Research, Biopolis, Singapore

Different mucosal adjuvanticity of polymyxin B for influenza virus and SARS-CoV-2

WS07-21-P〇 Naoto Yoshino, Takashi Odagiri, Masahiro Kimura, Yasushi Muraki
Division of Infectious Diseases and Immunology, Department of Microbiology, School of Medicine, Iwate Medical University, Iwate, Japan
WS07-22-P

	Senescence of alveolar epithelial cells impacts initiation and chronic phases of murine fibrosinginterstitial lung disease
1)
2, 3)
3)
4)
3)
〇 Junko Nishio , Zento Yamada , Kaori Motomura , Tetsuo Mikami , Toshihiro Nanki
1)

Department of Immunopathology and Immunoregulation, Toho University School of Medicine, 2)Department of Internal Medicine, Toho
University Graduate School of Medicine, 3)Division of Rheumatology, Department of Internal Medicine, Toho University School of Medicine,
4)
Department of Pathology, Toho University School of Medicine

December 7
WS08

Anti SARS-CoV-2 immune responses and Antibody producers

WS08-01-O/P

Role of germinal center response in the antibody responses against SARS-CoV-2 spike protein〇 Jumana Khalil , Kosuke Miyauchi , Yuichiro Yamamoto , Kouji Noguchi , Rina Hashimoto , Kazuo Takayama ,Masato Kubo1, 2)
1)

2)

3)

3)

4)

4)

1)
Division of Molecular Pathology, Research Institute for Biomedical Science, Tokyo University of Science, Noda, Japan, 2)Laboratory for
Cytokine Regulation, Center for Integrative Medical Sciences, RIKEN, Yokohama, Japan, 3)Department of Pharmaceutical Sciences, Faculty of
Pharmaceutical Sciences, Tokyo University of Science, Noda, Japan, 4)Center for iPS Cell Research and Application, Kyoto University, Kyoto, Japan

WS08-02-P

Development of neutralizing antibodies for SARS-CoV-2 by analyzing B cell receptors in FFPE lung lobe
〇 Sadahiro Iwabuchi , Tomohide Tsukahara , Toshitugu Okayama , Tadashi Imafuku , Kazuho Ikeo ,Toshikazu Kondo4), Toshihiko Torigoe2), Hiroki Yamaue5), Shinichi Hashimoto1)
1)

2)

3)

1)

3)

1)

Department of Molecular Pathophysiology, Wakayama Medical University, Wakayama, Japan, 2)Department of Pathology, Sapporo Medical
University School of Medicine, Hokkaido, Japan, 3)Laboratory of DNA Data Analysis, National Institute of Genetics, Shizuoka, Japan,
4)
Department of Forensic Medicine, Wakayama Medical University, Wakayama, Japan, 5)Department of Cancer Immunology, Wakayama Medical
University, Wakayama, Japan
WS08-03-P

	Early CD4+T cell responses elicited by COVID-19 mRNA vaccine predicts long term immunologicalmemory
1)
1)
2)
1, 2)
1, 2)
2)
1)
〇 Jie Bai , Asako Chiba , Goh Murayama , Taiga Kuga , Yoshiyuki Yahagi , Naoto Tamura , Sachiko Miyake

1)
Juntendo University Graduate School of Medicine, Department of Immunology, 2)Juntendo University School of Medicine, Department ofInternal Medicine and Rheumatologyc

WS08-04-P

Prediction of the structure of IRF4 transcription factor complex and control of IRF4 complex formation〇 Katsuya Sato, Hitoshi Nagaoka
Department of Molecular Pathobiochemistry, Gifu University School of Medicine, Gifu, Japan

WS08-05-P

Distinctive high expression of antiretroviral APOBEC3 protein in germinal center B cells〇 Shota Tsukimoto , Sachiyo Tsuji-Kawahara , Takuji Enya , Yoshiyuki Hakata , Tetsuo Tsukamoto ,Masaaki Miyazawa2, 4)
1, 2)

2)

1)

2)

2)

3)

Department of Anesthesiology, Faculty of Medicine, Kindai University, Osaka, Japan, 2)Department of Immunology, Faculty of Medicine, Kindai
University, Osaka, Japan, 3)Department of Health Informatics, Niigata University of Health and Welfare, Niigata, Japan, 4)Anti-Aging Center,
Kindai University, Osaka, Japan103

WS08-06-P

STAP-1 regulates germinal center formation through CD40 signals in B cells〇 Shoya Kawahara , Jun-Ichi Kashiwakura , Kenji Oritani , Tadashi Matuda
1)

2)

3)

1)

1)

Department of Immunology, Graduate School of Pharmaceutical Sciences, Hokkaido University, Hokkaido, Japan, 2)Department of Life Science,
Faculty of Pharmaceutical Sciences, Hokkaido University of Science, Hokkaido, Japan, 3)Department of Hematology, International University of
Health and Welfare, Tochigi, Japan
WS08-07-O/P	
STIM-mediated store-operated calcium entry regulates maintenance and selection of germinal center B cells
1)
2)
3)
4)
3, 5)
1)
〇 Yutaro Yada , Masanori Matsumoto , Takeshi Inoue , Daisuke Kitamura , Tomohiro Kurosaki , Yoshihiro Baba

1)

Division of Immunology and Genome Biology, Medical Institute of Bioregulation, Kyushu University, Fukuoka, Japan, 2)Department of
Pathology and Rogel Cancer Center, University of Michigan Medical School, Ann Arbor, MI, USA., 3)Laboratory for Immune Response
Dynamics, WPI Immunology Frontier Research Center, Osaka University, Suita, Osaka, Japan., 4)Division of Molecular Biology, ResearchInstitute for Biomedical Sciences, Tokyo University of Science, Noda, Chiba, Japan, 5)Laboratory for Lymphocyte Differentiation, RIKEN Center
for Integrative Medical Sciences (IMS), Yokohama, Kanagawa, Japan
WS08-08-P

The dynamics of essential trace element metabolism in B cell immune response〇 Akihiko Muto
Department of Biochemistry, Tohoku University Graduate School of Medicine

WS08-09-O/P

The effect of iron metabolism on antibody production of B cell
〇 Mayuko Shimoda , Mayumi Niimura , Yuki Takeshima , Chanida Thinyakul , Narumi Harada , Saisai Liu ,Toshiro Moroishi1, 2)
1)

1)

1)

1)

1)

1)

1)

Department of Cell Signaling and Metabolic Medicine, Faculty of Life Sciences, Kumamoto University, 2)Center for Metabolic Regulation of
Healthy Aging, Faculty of Life Sciences, Kumamoto University
WS08-10-O/P

	HNRNPU Promotes Antibody Class Switch Recombination through NHEJ and R-loop Regulation at the IgH
locus
1, 2)
1)
3)
1)
4)
1)
〇 Ahmed M. Refaat , Nasim A. Begum , Afzal Husain , Mikiyo Nakata , Hidetaka Kosako , Tasuku Honjo

1)

Department of Immunology and Genomic Medicine, Center for Cancer Immunotherapy and Immunobiology, Kyoto University Graduate Schoolof Medicine, Kyoto, Japan, 2)Zoology Department, Faculty of Science, Minia University, El-Minia, Egypt, 3)Department of Biochemistry, Faculty ofLife Sciences, Aligarh Muslim University, Aligarh, Uttar Pradesh, India, 4)Division of Cell Signaling, Institute of Advanced Medical Sciences, The
University of Tokushima, Tokushima, Japan
WS08-11-O/P

NOP16, a novel regulator of histone modification, regulates B-cell class switch recombination〇 Yohana Mtali, Ken Takashima, Atsushi Irie, Hiroyuki Oshiumi
Department of Immunology, Graduate school of medical science, Kumamoto University, Kumamoto, Japan

WS08-12-P

	PP2A family molecule is involved in the regulation of IgE class switch recombination and thedifferentiation in human peripheral blood B cells〇 Kano Tanabe, Yukinori Kozuma
Faculty of Health Science, Kumamoto Health Science Uniersity, Japan

WS08-13-O/P

Novel strategy for treatment of allergic diseases by regulation of IgA class switching〇 Naoki Morita , Reiko Shinkura , Hirotatsu Kojima
1)

1)

2)

1)

Laboratory of Immunology and Infection Control, Institute for Quantitative Biosciences, The University of Tokyo, 2)Drug Discovery Initiative,
Graduate School of Pharmaceutical Sciences, The University of Tokyo

WS08-14-O/P	Identification of IgA autoantibodies against glomerular mesangial cells and the target autoantigen using
an IgA nephropathy mouse model
1, 2)
2)
2)
1)
2)
1)
〇 Yoshihito Nihei , Kei Haniuda , Mizuki Higashiyama , Hiroyuki Iwasaki , Shohei Asami , Yusuke Suzuki ,2)Daisuke Kitamura
1)
Department of Nephrology, Juntendo University Faculty of Medicine, Tokyo, Japan., 2)Division of Cancer Cell Biology, Research Institute for
Biomedical Sciences (RIBS), Tokyo University of Science, Noda, Japan

WS08-15-P

A mechanism for anti-mesangium IgA production in an IgA nephropathy mouse model
1)
1, 2)
3)
1)
1)
〇 Mizuki Higashiyama , Kei Haniuda , Yoshihito Nihei , Riku Hisato , Daisuke Kitamura

1)
Division of Molecular Biology, Research Institute for Biomedical Sciences(RIBS), Tokyo University of Science, Chiba, Japan, 2)Department of
Immunology, University of Toronto, Toronto, Canada, 3)Department of Nephrology, Juntendo University Faculty of Medicine, Tokyo, Japan104

Immunoglobulin A deficiency breaks immunological and neurological homeostasis

WS08-16-O/P〇 Takahiro Adachi
Medical Research Institute, Tokyo Medical and Dental University, Japan

Deduced function of DOCK11 in B cells in secondary immune responses with protein antigens

WS08-17-P〇 Yuma Sugiyama , Mitsuhiro Fujiwra , Akihiko Sakamoto , Akihiko Nishikimi , Mitsuo Maruyama
1)

2)

1)

2)

1, 3)

1)

Department of Inflammation and Immunosenescence, Geroscience Research Center, Research Institute, National Center for Geriatrics andGerontology, Obu, Aichi, Japan, 2)Biosafety Division, Research Institute, National Center for Geriatrics and Gerontology, Obu, Aichi, Japan,
3)
Department of Aging Research, Nagoya University Graduate School of Medicine, Nagoya, Japan

Histone variant H3.3 expression controls the plasma cell differentiation

WS08-18-P〇 Yuichi Saito , Yoshihiro Baba , Yasuyuki Ohkawa , Akihito Harada
1)

1)

2)

2)

1)

Division of Immunology and Genome Biology, Medical Institute of Bioregulation, Kyushu University, Fukuoka, Japan, 2)Division ofTranscriptomics, Medical Institute of Bioregulation, Kyushu University, Fukuoka, Japan

WS08-19-O/P	The regulation of B cell chromatin by a non-histone chromatin protein PC4 and its interacting transcription
factors〇 Kyoko Ochiai, Kazuhiko Igarashi
Tohoku University Graduate School of Medicine

Genetic tracing of plasma cells reveals cellular dynamism during entry to long-lived compartment

WS08-20-O/P

1, 2)
2, 3)
2, 4)
2, 3)
2, 3)
2, 3)
〇 Takuya Koike , Kentaro Fujii , Kohei Kometani , Shinya Yari , Junichi Kikuta , Masaru Ishii ,2)
1, 2)
Tomohiro Kurosaki , Wataru Ise
1)
Center for Infectious Disease Education and Research, Osaka University, Osaka, Japan, 2)WPI Immunology Frontier Research Center, Osaka
University, Osaka, Japan, 3)Graduate School of Medicine and Frontier Biosciences, Osaka University, Osaka, Japan, 4)Center for iPS Cell
Research and Application, Kyoto University, Kyoto, Japan

In vivo predominant immunoglobulin secretion in the bone marrow IgG-secreting plasma cells

WS08-21-O/P〇 Shogo Tsuda, Harumi Sasaki, Akihiko Murata, Koji Tokoyoda
Division of Immunology, School of Life Science, Faculty of Medicine, Tottori University, Yonago, Japan
WS08-22-O/P	Lymphocyte infiltration into liver was enhanced in high-fat diet-loaded LDL receptor and MD-1 doubledeficient mice
〇 Sachiko Akashi-Takamura, Mrityunjoy Biswas, Susumu Tomono, Tatsuya Yamazaki, Masanori Inui,
Sajid Iftekhar Chowdhury
Department of Microbiology and Immunology, Aichi Medical University, School of Medicine, Nagakute, Japan

December 7
WS09

Molecular and cellular diversity of allergic disease

WS09-01-O/P

Spontaneous dermatitis associated with elevated sebaceous lipid production in Tmem79-deficient mice
1, 2)
1, 2)
1, 2)
1, 2)
3, 4)
5, 6)
〇 Ari Morimoto , Keitaro Fukuda , Yoshihiro Ito , Hiroshi Kawasaki , Eiryo Kawakami , Makoto Arita ,7)
1, 2, 8)1, 2)Haruhiko Koseki , Takeshi Matsui, Masayuki Amagai
1)
Department of Dermatology, Keio University School of Medicine, Tokyo, Japan, 2)Laboratory for Skin Homeostasis, RIKEN Center for Integrative
Medical Sciences, Yokohama, Japan, 3)Advanced Data Science Project (ADSP), RIKEN Information R&D and Strategy Headquarters, Yokohama,Japan, 4)Artificial Intelligence Medicine, Graduate School of Medicine, Chiba University, Chiba, Japan, 5)Division of Physiological Chemistry andMetabolism, Faculty of Pharmacy, Keio University, Tokyo, Japan, 6)Laboratory for Metabolomics, RIKEN Center for Integrative Medical Sciences,
Yokohama, Japan, 7)Laboratory for Developmental Genetics, RIKEN Center for Integrative Medical Sciences, Yokohama, Japan, 8)Laboratory for
Evolutionary Cell Biology of the Skin, School of Bioscience and Biotechnology, Tokyo University of Technology, Hachioji, Japan

WS09-02-O/P

Elucidation of the pathogenesis of spontaneous dermatitis in Foxp3 Bcl6 cDKO mice
〇 Yuki Tai , Shuhei Ogawa , Yohsuke Harada
1)

2)

1)

1)

Laboratory of Pharmaceutical Immunology, Faculty of Pharmaceutical Sciences, Tokyo University of Science, Chiba, Japan, 2)Division ofIntegrated Research, Research Institute for Biomedical Sciences, Tokyo University of Science, Chiba, Japan105

WS09-03-O/P	T cell-specific deletion of Pgam1, a glycolytic enzyme, ameliorates the symptoms of allergic contact
dermatitis in mice
〇 Miyuki Omori-Miyake , Masakatsu Yamashita
1)

1, 2)

1)

Dept. of Infections and Host Defenses, Ehime University Graduate School of Medicine, 2)Dept. of Immunology, Ehime University Graduate
School of Medicine
WS09-04-O/P	Decomposition of Atopic dermatitis skin RNA-seq data reveals diverse immune pathways in its
pathogenesis
1)
1, 2)
1)
3)
1)
〇 Ayano Fukushima-Nomura , Hiroshi Kawasaki , Keiji Tanese , Eiryo Kawakami , Masayuki Amagai

1)

Department of Dermatology, Keio University School of Medicine, 2)RIKEN Center for Integrative Medical Sciences, 3)RIKEN Advanced Data
Science Project
WS09-05-O/P

Inflammatory and pruritogenic actions of Oncostatin-M (OSM) in the pathogenesis of atopic dermatitis
1, 2, 3), Hiroshi Kawasaki1, 2, 3), Sonoko Takahashi4), Sotaro Ochiai4), Takaharu Okada4),〇 Tomohiro Miyai
2, 5)
Masayuki Amagai , Haruhiko Koseki1, 6)
1)

Laboratory for Developmental Genetics, RIKEN IMS, Yokohama, Japan, 2)Department of Dermatology, Keio University School of Medicine,Tokyo, Japan, 3)Development Theme for Atopic Dermatitis Therapeutics, RIKEN DMP, Yokohama, Japan, 4)Laboratory for Tissue Dynamics,
RIKEN IMS, Yokohama, Japan, 5)Laboratory for Skin Homeostasis, RIKEN IMS, Yokohama, Japan, 6)Department of Cellular and Molecular
Medicine, Chiba University School of Medicine, Chiba, Japan
WS09-06-O/P	Skin treatment with detergent induces dermatitis with H1 antihistamine-refractory itch and upregulates
IL-4 and Th17/Th22 cytokine gene expression in C57BL/6 mice
1)
1, 2)
1, 2)
1, 2)
3)
2)
〇 Seiji Kamijo , Yurie Masutani , Toru Kimitsu , Tomoko Yoshimura , Saori Ichikawa , Takasuke Ogawa ,
1)
1, 2)
1)
1)
4)
4)
Mitsutoshi Tominaga , Hajime Suto , Kenji Takamori , Shigaku Ikeda , Ko Okumura , Toshiro Takai
1)
Atopy (Allergy) Research Center, Juntendo University Graduate School of Medicine, 2)Department of Allergology and Dermatology, Juntendo
University Graduate School of Medicine, 3)Department of Materials and Biological Sciences, Japan Women’s University, 4)Juntendo Itch ResearchCenter (JIRC), Juntendo University Graduate School of Medicine

WS09-07-O/P	Mead acid (5,8,11-eicosatrienoic acid) inhibits retinol-induced irritant contact dermatitis through PPARαmediated pathway
1)
1, 2)
1, 3)
1)
1)
4)
5)
〇 Azusa Saika , Prabha Tiwari , Takahiro Nagatake , Koji Hosomi , Eri Node , Tetsuya Honda , Kenji Kabashima ,1)
Jun Kunisawa
1)
Laboratory of Vaccine Materials, Center for Vaccine and Adjuvant Research, and Laboratory of Gut Environmental System, Collaborative
Research Center for Health and Medicine, National Institutes of Biomedical Innovation, Health and Nutrition (NIBIOHN), Ibaraki, Osaka,
2)
Laboratory for Transcriptome Technology, RIKEN Center for Integrative Medical Sciences, Yokohama, Kanagawa, 3)Laboratory of Functional
Anatomy, Department of Life Sciences, School of Agriculture, Meiji University, Kawasaki, Kanagawa, 4)Department of Dermatology, Hamamatsu
University School of Medicine, Hamamatsu, Shizuoka, 5)Department of Dermatology, Graduate School of Medicine, Kyoto University, Kyoto, Kyoto

WS09-08-O/P

DOCK2 is essential for MRGPRX2/B2-mediated mast cell degranulation and drug-induced anaphylaxis〇 Kazufumi Kunimura, Yoshinori Fukui
Division of Immunogenetics, Medical Institute of Bioregulation, Kyushu University, Fukuoka, Japan

WS09-09-O/P

Pollen shells promote allergic conjunctivitis through inducible goblet cell-associated antigen passage
1, 2, 3), Tomoaki Ando1), Yasuharu Kume1, 2, 3), Saaya Fukase1, 2, 3), Moe Matsuzawa1, 2, 3), Kumi Izawa1),〇 Meiko Kimura
1)
Ayako Kaitani , Nobuhiro Nakano1), Ko Okumura1), Akira Murakami3), Nobuyuki Ebihara2, 3), Jiro Kitaura1, 4)
1)
Atopy (Allergy) Research Center, Juntendo University Graduate School of Medicine (Tokyo, Japan), 2)Department of Ophthalmology, Juntendo
University Urayasu Hospital (Chiba, Japan), 3)Department of Ophthalmology, Juntendo University Graduate School of Medicine (Tokyo, Japan),4)
Department of Science of Allergy and Inflammation, Juntendo University Graduate School of Medicine (Tokyo, Japan)

WS09-10-P

Analysis of lymphocyte differentiation and proliferation in NC/Nga mice
〇 Hikaru Tsuzuki , Miyoko Matsushima , Ayumi Tajima , Moeko Ohara , Nodoka Shimasaki , Hinata Taniguchi ,Hina Kawashima2), Sayaka Takagi2), Fuzuki Hayashi2), Nanami Yoshida2), Tsutomu Kawabe1)
1)

1)

1)

1)

1)

1)

1)

Department of Integrated Health Sciences, Nagoya University Graduate School of Medicine, Aichi, Japan, 2)Department of Medical Technology,
Nagoya University School of Health Sciences, Aichi, Japan106

WS09-11-P

	Chronic psychological stress exacerbates IgE-dependent chronic allergic inflammation by suppressing
M2-macrophage-mediated efferocytosis〇 Hitoshi Urakami , Yuki Fujita , Kei Nagao , Kensuke Miyake , Hajime Karasuyama , Sachiko Miyake ,Soichiro Yoshikawa1, 3)
1)

1)

1)

2)

2)

3)

1)
Department of Cellular Physiology, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama,
Japan, 2)Inflammation, infection and Immunity Laboratory, Advanced Research Institute, Tokyo Medical and Dental University (TMDU), Tokyo,
Japan, 3)Department of Immunology, Juntendo University School of Medicine, Tokyo, Japan

WS09-12-P

Treg transfer cures atopic skin disorders caused by a loss-of-function genetic CARD11 mutation
1)
1, 2)
3)
1)
1)
4)
〇 Yuki Oyamada , Yusuke Nomoto , Shinsuke Yasukawa , Daiji Sakata , Ei'Ichi Iizasa , Shohei Hori ,Takuro Kanekura2), Hiromitsu Hara1)
1)

Department of Immunology, Kagoshima University Graduate School of Medical and Dental Sciences, Kagoshima, Japan, 2)Department of
Dermatology, Kagoshima University Graduate School of Medical and Dental Sciences, Kagoshima, Japan, 3)Department of Dermatology,
Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan, 4)Laboratory for Immunology and Microbiology, Graduate School of
Pharmaceutical Sciences, The University of Tokyo, Tokyo, Japan
WS09-13-P

Effects of Josamycin on Scratching Behavior in NC/Nga Mice with Atopic Dermatitis-Like Skin Lesion〇 Katsuhiko Matsui
Department of Clinical Immunology, Meiji Pharmaceutical University, Tokyo, Japan

WS09-14-P

Withdrawn

WS09-15-P

Modulation of proinflammatory responses by diazinon in mast cells〇 Moeko Ohara , Miyoko Matsushima , Hina Kawashima , Hikaru Tsuzuki , Nodoka Shimasaki , Ayumi Tajima ,Hinata Taniguchi1), Sayaka Takagi2), Fuzuki Hayashi2), Nanami Yoshida2), Tsutomu Kawabe1)
1)

1)

1)

2)

1)

1)

1)
Department of Integrated Health Sciences, Nagoya University Graduate School of Medicine, Aichi, Japan, 2)Department of Medical Technology,
Nagoya University School of Health Sciences, Aichi, Japan

WS09-16-P

Salicylaldehyde ameliorates mouse anaphylaxis via suppression of IgE-mediated mast cell activation〇 Tsubasa Ashikari, Kazuki Nagata, Yuki Iizuka, Masakazu Hachisu, Chiharu Nishiyama
Department of Biological Science an Technology, Tokyo University of Science, Tokyo, Japan

WS09-17-P

In vitro generation of IL-9-producing mucosal mast cells from bone marrow cells〇 Nobuhiro Nakano, Jiro Kitaura, Hideoki Ogawa, Ko Okumura
Atopy (Allergy) Research Center, Juntendo University Graduate School of Medicine

WS09-18-P	
α-glucosidase inhibitor acarbose suppresses mast cell degranulation and systemic anaphylaxis throughthe gut microbiota
1, 2)
2)
1)
〇 Kyosuke Yakabe , Koji Hase , Yun-Gi Kim
1)

Research Center for Drug Discovery, Faculty of Pharmacy, Keio University, Tokyo, Japan, 2)Division of Biochemistry, Faculty of Pharmacy, Keio
University, Tokyo, Japan
WS09-19-P

	ADAR1 in bronchial epithelial cells is involved in the airway mucosal immune system in a mouse modelof asthma〇 Ayae Tanaka , Nobuhide Tsuruoka , Toshibumi Taniguchi , Masahiko Hatano , Takayoshi Owada ,Hirokuni Hirata5), Kazuhiro Kurasawa1), Masafumi Arima1)
1)

2)

3)

4)

5)

1)
Department of Rheumatology, Dokkyo Medical University, School of Medicine, Tochigi, Japan, 2)Department of Reproductive Medicine,
Graduate School of Medicine, Chiba University, Chiba, Japan, 3)Department of Infectious Diseases, Chiba University Hospital, Chiba, Japan,
4)
Department of Biomedical Science (M14), Graduate School of Medicine, Chiba University, Chiba, Japan, 5)Department of Respiratory Medicine
and Clinical Immunology, Dokkyo Medical University Saitama Medical Center, Saitama, Japan107

WS09-20-P

	The emerging role of periostin in NF-κB–mediated inflammation with type 2 inflammation and itching inallergic skin inflammation〇 Satoshi Nunomura , Daisuke Uta , Isao Kitajima , Yasuhiro Nanri , Kosuke Matsuda , Midori Kitajima ,Naoko Ejiri3), Yuko Honda1), Hironobu Takedomi1), Tsugunobu Andoh4), Simon J Conway5)
1)

2)

3)

1)

2)

3)

1)

Division of Medical Biochemistry, Department of Biomolecular Sciences, Saga Medical School, 2)Department of Applied Pharmacology, Facultyof Pharmaceutical Sciences, University of Toyama, 3)Department of Clinical Laboratory and Molecular Pathology, Graduate School of Medical
and Pharmaceutical Science, University of Toyama, 4)Department of Pharmacology and Pathophysiology, College of Pharmacy, Kinjo Gakuin
University, 5)Herman B. Wells Center for Pediatric Research, Indiana University School of Medicine, Indianapolis

December 7
WS10

T cell function and diseases-1 (Disease models and SARS-CoV-2)

WS10-01-O/P

CD4+ skin-resident memory T cells persist in CD68+ cellular niches〇 Akihiko Murata, Momoka Wakazuki, Koji Tokoyoda
Division of Immunology, Department of Molecular and Cellular Biology, School of Life Science, Faculty of Medicine, Tottori University, Tottori,
Japan

WS10-02-O/P	A gain-of-function mutation of immunoreceptor DNAM-1 exacerbates CD4+ T cell-mediated autoimmune
inflammation
1, 2)
1, 2)
1, 3)
4)
1, 3, 5),
〇 Rikito Murata , Shota Kinoshita , Kenshiro Matsuda , Atsushi Kawaguchi , Akira Shibuya
1, 5)Kazuko Shibuya
1)

Department of Immunology, Faculty of Medicine, University of Tsukuba, 2)Ph.D. Program in Human Biology, University of Tsukuba, 3)LifeScience Center for Survival Dynamics, Tsukuba Advanced Research Alliance (TARA), University of Tsukuba, 4)Infection Biology, Faculty of
Medicine, University of Tsukuba, 5)R&D Center for Innovative Drug Discovery, University of Tsukuba
WS10-03-O/P

NRP1 marks a pathogenic self-reactive Th subset in autoimmune disease〇 Ben Raveney , Shohei Hori , Wakiro Sato , Takashi Yamamura , Shinji Oki
1)

2)

1)

1)

1)

1)

2)

Department of Immunology, National Institute of Neuroscience, NCNP, Kodaira, Tokyo, Japan, Laboratory for Immunology and Microbiology,
Graduate School of Pharmaceutical Sciences, University of Tokyo, Japan
WS10-04-O/P

Role of γδ T cells in antigen specific CD4+ T cell response to Plasmodium chabaudi infection〇 Yarob Ibraheem , Ganchimeg Bayarsaikhan , Maria Lourdes Macalinao , Kazumi Kimura , Katsuyuki Yui
Shin-Ichi Inoue1)
1)

1)

2)

1)

1, 2, 3),

1)
Division of Immunology, Department of Molecular Microbiology and Immunology, Graduate School of Biomedical Sciences, Nagasaki
University, 2)School of Tropical Medicine and Global Health, Nagasaki University, 3)Institute of Tropical Medicine, Nagasaki University

WS10-05-O/P

Cytotoxic CD8+ T cells simultaneously expressing GZMA, GZMB and Perforin regulate COVID-19 severity
1, 2)
3)
1)
1, 2)
4)
5)
〇 Takuto Nogimori , Koichiro Suzuki , Yuji Masuta , Ayaka Washizaki , Hidenori Kanda , Minoru Takada ,
6)
6)
1, 2)
3, 7, 8)1, 2, 6, 9, 10)
Shohei Minami , Takeshi Kobayashi , Shokichi Takahama , Yasuo Yoshioka, Takuya Yamamoto
1)
Laboratory of Immunosenescence, Center for Vaccine and Adjuvant Research, National Institutes of Biomedical Innovation, Health andNutrition, Osaka, Japan, 2)Research Institute for Microbial Diseases, Osaka University, Osaka, Japan, 3)The Research Foundation for Microbial
Diseases of Osaka University (BIKEN), Osaka, Japan, 4)KINSHUKAI, Hanwa Memorial Hospital, Osaka, Japan, 5)KINSHUKAI, Hanwa The Second
Senboku Hospital, Osaka, Japan, 6)Department of Virology, Research Institute for Microbial Diseases, Osaka University, Osaka, Japan, 7)Vaccine
Creation Group, BIKEN Innovative Vaccine Research Alliance Laboratories, Research Institute for Microbial Diseases, Osaka University, Osaka,
Japan, 8)Institute for Open and Transdisciplinary Research Initiatives, Osaka University, Osaka, Japan, 9)Laboratory of Aging and Immune
Regulation, Graduate School of Pharmaceutical Sciences, Osaka University, Osaka, Japan, 10)Department of Virology and Immunology, Graduate
School of Medicine, Osaka University, Osaka, Japan

WS10-06-O/P

T cell responses induced by SARS-Cov-2 mRNA vaccination are associated with clonal replacement
1, 2)
3)
1)
3)
3)
〇 Hiroyasu Aoki , Masahiro Kitabatake , Shigeyuki Shichino , Atsushi Hara , Noriko Ouji-Sageshima ,3)
1)
1)
Toshihiro Ito , Kouji Matsushima , Satoshi Ueha
1)
Division of Molecular Regulation of Inflammatory and Immune Diseases, Research Institute for Biomedical Sciences, Tokyo University of
Science, Chiba, Japan., 2)Department of Hygiene, Graduate School of Medicine, The University of Tokyo., 3)Department of Immunology, Nara
Medical University, Nara, Japan

WS10-07-O/P

In vivo generation of designer APCs with mRNA regulates T cell immune responses
1, 2)
1)
1)
1)
1, 2)
〇 Tomoyoshi Yamano , Shota Imai , Toan Le , Xiabing Lyu , Rikinari Hanayama
1)

Department of Immunology, Graduate School of Medical Sciences, Kanazawa University, 2)WPI Nano Life Science Institute (NanoLSI),
Kanazawa University

108

WS10-08-P

	A novel authentic SARS-CoV-2-based assay for unveiling antiviral functions of vaccine-induced T cell
immunity
1, 2)
1)
1, 2)
〇 Mako Toyoda , Chihiro Motozono , Takamasa Ueno
1)

Division of Infection and Immunity, Joint Research Center for Human Retrovirus Infection, Kumamoto University, Kumamoto, Japan, 2)Graduate
School of Medical Sciences, Kumamoto University, Kumamoto, Japan

WS10-09-P

Analysis of immune responses to COVID-19 vaccine in liver transplant recipients
1, 2)
1)
1, 2)
2)
2)
〇 Yuta Nagatsuka , Takuto Nogimori , Hirotomo Murakami , Shogo Kobayashi , Yoshifumi Iwagami ,
2)
2)
2)
2)
2)
Daisaku Yamada , Yoshito Tomimaru , Takehiro Noda , Hidenori Takahashi , Yuichiro Doki , Hidetoshi Eguchi2),
Takuya Yamamoto1, 3, 4, 5, 6)
1)

Laboratory of Immunosenescence, National Institutes of Biomedical Innovation, Health and Nutrition, Osaka, Japan, 2)Department of Surgery,
Osaka Rosai Hospital, Osaka, Japan, 3)Research Institute for Microbial Diseases, Osaka University, Osaka, Japan, 4)Laboratory of Aging and
Immune Regulation, Graduate School of Pharmaceutical Sciences, Osaka University, Osaka, Japan, 5)Department of Virology, Research Institutefor Microbial Diseases, Osaka University, Osaka, Japan, 6)Department of Virology and Immunology, Graduate School of Medicine, Osaka
University, Osaka, Japan
WS10-10-P

	Structural basis of antigen recognition by distinct public TCRs recognizing an identical epitope conserved
across SARS-CoV-2 variants
1, 2)
1, 2)
1, 2)
1, 2)
1, 2)
〇 Masamichi Nagae , Shotaro Mori , Taiki Ito , Xiuyuan Lu , Sho Yamasaki
1)

Research Institute for Microbial Diseases, Osaka University, 2)Immunology Frontier Research Center (IFReC), Osaka University

WS10-11-P

Vitamin C treatment promotes the persistence and immune responses of CD8+ T cells〇 Kenta Kondo, Tatsuya Hasegawa, Koji Terada, Yasutoshi Agata
Department of Biochemistry and Molecular Biology, Shiga University of Medical Science, Shiga, Japan

WS10-12-P

Induction of immunogical memory in mice administrated with OML-based vaccine〇 Emi Onohara, Naoya Kojima
Department of Applied Biochemistry, Tokai Uiversity

WS10-13-P

Revealing the mechanism of immune surveillance of T cells in the skin
〇 Mami Ishibashi, Gyohei Egawa, Satoshi Nakamizo, Kenji Kabashima
Department of Dermatology, Kyoto University Graduate School of Medicine, Kyoto, Japan

WS10-14-P

Development of a novel contact hypersensitivity model using humanized NOG-hIL-4 Tg mice
〇 Yusuke Ohno
Central Institute for Experimental Animals

WS10-15-P

Activation of IL-1 signaling pathways induce a unique T cell subset, GM-CSF producing CD4+ T cells〇 Sho Ishigaki, Keiko Yoshimoto, Mitsuhiro Akiyama, Kotaro Matsumoto, Katsuya Suzuki, Yuko Kaneko
Division of Rheumatology, Department of Internal Medicine, Keio University School of Medicine, Tokyo, Japan

WS10-16-P

Loss-of-function mutation in human PDLIM1 causes immunodeficiency by T cell exhaustion〇 Takashi Tanaka , Christoph Geier
1)

2, 3, 4)

1)

Laboratory for Inflammatory Regulation, REKEN Center for Integrative Medical Sciences、Yokohama, JAPAN, 2)Immunology Outpatient Clinic,
Vienna, Austria, 3)Department of Rheumatology and Clinical Immunology, University Medical Center Freiburg, Freiburg, Germany, 4)Center for
Chronic Immunodeficiency (CCI), University Medical Center Freiburg, Freiburg, Germany
WS10-17-P

Themis in peripheral CD8 T cells regulates hapten-induced allergic skin inflammation〇 Masayuki Kitajima, Harumi Suzuki, Takayuki Okada
Research Institute National Center for Global Health and Medicine, Dept. of Immunology and Pathology, Chiba, Japan

WS10-18-P

IL-7 regulates the expression of CD69 and CD103 on TRM cells in skin
〇 Marii Ise, Taku Kuwabara, Yuriko Tanaka, Taku Naito, Motonari Kondo
Department of Molecular Immunology, Faculty of Medicine, Toho University, Tokyo, Japan

WS10-19-P

Elevated expression of a novel immune checkpoint molecule, ILDR2 in inflammatory brain〇 Chenyang Zhang, Farzana Sultana, Shigenori Nagai, Miyuki Azuma
Department of Molecular Immunology, Graduate School of Medical and Dental Sciences, Tokyo Medical and Dental University (TMDU)

109

WS10-20-P

	A selective PPARα modulator-mediated metabolic manipulation ameliorates autoimmunity by limiting
glutaminolysis in Th17 cells〇 Satoshi Masuyama , Masayuki Mizui , Masashi Morita , Tatsusada Okuno , Yoshitaka Isaka
1)

1)

2)

3)

1)

1)

2)

Department of Nephrology, Osaka University Graduate School of Medicine, Osaka, Japan, Department of Nephrology, National Hospital
Organization Osaka Minami Medical Center, Osaka, Japan, 3)Department of Neurology, Osaka University Graduate School of Medicine, Osaka, Japan
WS10-21-P

	Mitochondrial cysteinyl-tRNA synthetase (CARS2)-dependent sulfur metabolism exacerbates
experimental autoimmune encephalomyelitis in mice
〇 Kyoga Hiraide, Yuya Kitamura, Shunichi Tayama, Yuko Okuyama, Kosuke Sato, Hibiki Suzuki, Keita Koinuma,
Takeshi Kawabe, Naoto Ishii
Department of Microbiology and Immunology, Tohoku University Graduate School of Medicine, Japan

In vitro generation of brain regulatory T cells by co-culturing with astrocytes

WS10-22-P

1, 2)
2)
3)
〇 Shinichi Yamamoto , Akihiko Yoshimura , Minako Ito

1)Center for Immune Therapeutics and Diagnosis, Advanced Research Institute for Health Science, Juntendo University, 2)Department ofMicrobiology and Immunology, Keio University School of Medicine, 3)Division of Allergy and Immunology, Medical Institute of Bioregulation,
Kyushu University

Clonally expanded CD8+ T cells in early phase of β-amyloid pathology in Alzheimer’s disease model mouse

WS10-23-P〇 Masaki Ohyagi , Minako Ito , Akihiko Yoshimura
1)

2)

1)

1)

2)

Keio University School of Medicine, Tokyo, Japan, Medical Institute of Bioregulation, Kyushu University, Fukuoka, Japan

Induction of Eomes-expressing Th cells via upregulation of type I interferon

WS10-24-P〇 Tzu Wen Yeh , Chenyang Zhang , Ben Raveney , Fumio Takahashi , Marco Prinz , Takashi Yamamura ,Shinji Oki1)
1)

1)

1)

1)

1)

2)

1)

Department of Immunology, National Center of Neurology and Psychiatry, Tokyo, JP, 2)Institute of Neuropathology, University of Freiburg,
Freiburg, Germany

Analysis of Brain Immune Cells in Autism Spectrum Disorder

WS10-25-P〇 Natsumi Awata, Ako Matsui, Yutaro Kobayashi, Minako Ito
Medical Institute of Bioregulation, Kyushu University, Fukuoka, Japan

December 8
WS11

Tumor Immunotherapy

WS11-01-P	In vivo visualization of the immune responses of CAR-T cells against B cell lymphoma using an intravital
imaging technique〇 Erika Yamashita , Kaho Fujii , Raizo Yamamoto , Masaru Ishii
1)

2)

2)

1, 2)

1)

Department of Immunology and Cell Biology, Graduate School of Medicine, Osaka University, 2)Department of Immunology and Cell Biology,
Graduate School of Frontier Bioscience, Osaka University
WS11-02-P	CD62L expression levels in the peripheral blood T cells predict the generation of antitumor T cell grafts
with long-lived potential〇 Hitomi Kasuya, Yuki Kagoya
Division of Immune Response, Aichi Cancer Center Research Institute, Nagoya, Japan

WS11-03-P

Antitumor efficacy of NR4a knock out HER2 CAR T-cell therapy for solid tumors〇 Kensuke Nakagawara , Makoto Ando , Tanakorn Srirat , Setsuko Mise-Omata , Mari Ikeda ,Shunsuke Chikuma2), Koichi Fukunaga1), Akihiko Yoshimura2)
1)

2)

2)

2)

2)

1)

Division of Pulmonary Medicine, Department of Medicine, Keio University School of Medicine, Tokyo, Japan., 2)Department of Microbiology
and Immunology, Keio University School of Medicine, Shinjuku-ku, Tokyo, Japan
WS11-04-O/P

	Exhaustion-resistant CAR-T cells by overexpressing dominant negative form of NR4A factors for thetreatment of solid tumors〇 Makoto Ando, Akihiko Yoshimura
Department of Microbiology and Immunology, Keio University School of Medicine, Tokyo, Japan110

WS11-05-O/P

Development of CART cell therapy against T cell malignancies〇 Keisuke Watanabe , Carl June , Hiroyoshi Nishikawa
1)

2)

1)

1)

National Cancer Research Center Research Institute Division of Cancer Immunology, Tokyo Japan, 2)Center for Cellular Immunotherapies,
Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA
WS11-06-O/P	A novel chimeric cytokine receptor-engineered CAR-T cells achieve both potent cytotoxicity and reduced
cytokine release syndrome〇 Toshiaki Yoshikawa, Yuki Kagoya
Aichi Cancer center, Aichi, Japan

WS11-07-O/P

	Targeting poor prognosis acute myeloid leukemia with CD25-targeted chemokine receptor expressing
CAR T cell therapy
1, 2)
1)
3)
3)
1)
〇 Ari Itoh-Nakadai , Mariko Murasawa-Tomizawa , Masashi Matsuda , Haruhiko Koseki , Fumihiko Ishikawa
1)

Laboratory for Human Disease Models, IMS, Riken, Yokohama, Japan, 2)Hygiene & public Health, Nippon Medical School, Tokyo, Japan,
Developmental Genetics, IMS,RIKEN, Yokohama, Japan3)

WS11-08-P	Targeting patient-specific anti-apoptotic molecules combined with CXCR4 expressing CAR T-cells
overcomes poor prognosis ALL
1, 2)
1)
1)
3)
4)
4)
〇 Ryo Nakagawa , Yoriko Saito , Ari Itoh-Nakadai , Shinsuke Takagi , Sadaaki Takata , Hanae Amitani ,
4)
3)
4)
3)
2)
Mikiko Endo , Naoyuki Uchida , Yukihide Momozawa , Shuichi Taniguchi , Hideo Harigae , Fumihiko Ishikawa1)
1)

Laboratory for Human Disease Models, RIKEN IMS, Yokohama, Kanagawa, Japan., 2)Department Hematology and Rheumatology, Tohoku Univ.,
Sendai, Miyagi, Japan., 3)Department of Hematology, Toranomon Hospital, Tokyo, Japan., 4)Laboratory for Genotyping Development, RIKEN IMS,
Yokohama, Kanagawa, Japan

WS11-09-O/P

Engineering immune cell network with advanced split CAR system〇 Atsushi Okuma

1, 2, 3)

1)

Department of Biomedical Engineering, Boston University, 2)Biological Design Center, Boston University, 3)Current affiliation; Center for
Exploratory Research, Hitachi, Ltd
WS11-10-O/P

Generation of genetically engineered TCR-T cells from self-renewing multipotent progenitor cells〇 Tsukasa Shigehiro, Tomokatsu Ikawa
Research Institute for Biomedical Sciences, Tokyo University of Science, Chiba, Japan

WS11-11-O/P

Harnessing arginine metabolism to overcome hyperthermia-induced metabolic dysfunction of CAR T-cells〇 Taisuke Kondo, Justyn Dusold, Naomi Taylor
National Cancer Institute, National Institutes of Health, Maryland, USA

WS11-12-P

Tracing the fate of Nivolumab–PD-1 complex via proximity biotinylation enzyme AirID〇 Haruka Higashiyama, Tatsuya Sawasaki
Proteo-Science Center (PROS), Ehime University, Ehime, Japan

WS11-13-P

Loss of tapasin confers the sensitivity to PD-1 blockade on lung cancer cells
1, 2)
1)
1)
1)
〇 Keigo Moniwa , Serina Tokita , Takayuki Kanaseki , Toshihiko Torigoe

1)

Department of Pathology, Sapporo Medical University, Sapporo, Japan, 2)Department of Respiratory Medicine, Sapporo Medical University,
Sapporo, Japan

WS11-14-O/P

	Aging-associated and CD4 T cell-dependent ectopic CXCL13 activation predisposes to anti-PD-1 therapyinduced adverse events〇 Hirotake Tsukamoto , Yoshihiro Komohara , Yusuke Tomita , Yuji Miura , Takanobu Motoshima ,Kosuke Imamura3), Toshiki Kimura3), Yukio Fujiwara2), Hiromu Yano2), Tomomi Kamba4), Takuro Sakagami3),
Hiroyuki Oshiumi5)
1)

2)

1)

3)

2)

4)

Division of Clinical Immunology and Cancer Immunotherapy, Center for Cancer Immunotherapy and Immunobiology, Graduate Schoolof Medicine, Kyoto University, 2)Department of Cell Pathology, Graduate School of Medical Sciences, Faculty of Life Sciences, Kumamoto
University, 3)Department of Respiratory Medicine, Graduate School of Medical Sciences, Faculty of Life Sciences, Kumamoto University,
4)
Department of Urology, Graduate School of Medical Sciences, Faculty of Life Sciences, Kumamoto University, 5)Department of Immunology,
Graduate School of Medical Sciences, Faculty of Life Sciences, Kumamoto University111

WS11-15-P

	Elucidation of immune response in murine models of pancreatic cancer receiving combination therapy of
proton beam irradiation and anti-PD-L1 antibody〇 Alessandro Nasti , Yoshio Sakai , Tuyen Thuy Bich Ho , Akihiro Seki , Shingo Inagaki , Norihiko Ogawa ,Kyo Kume4), Munetoshi Maeda4), Hiroyasu Tamamura5), Kazutaka Yamamoto5), Makoto Sasaki5), Shuichi Kaneko1, 2)
1)

2)

1)

2)

3)

3)

1)
Information-Based Medicine Development, Graduate School of Medical Sciences, Kanazawa University, Kanazawa, Japan., 2)Department
of Gastroenterology, Kanazawa University Hospital, Kanazawa, Japan., 3)System biology, Graduate School of Advanced Preventive Medical
Sciences, Kanazawa University, Kanazawa, Japan., 4)Proton Medical Research Division, Research & Development Department, The Wakasa Wan
Energy Research Center, Tsuruga, Japan, 5)Proton Therapy Center, Fukui Prefectural Hospital, Fukui, Japan

WS11-16-P

	Exploration of predictive markers for the efficacy of immune checkpoint inhibitors in metastatic renal cell
carcinoma〇 Ryuta Sobu, Soki Kashima, Mizuki Kobayashi, Ryohei Yamamoto, Taketoshi Nara, Kazuyuki Numakura,
Mitsuru Saito, Shintaro Narita, Tomonori Habuchi
Akita University Graduate School of Medicine, Department of Urology, Akita, Japan

WS11-17-P

Effects of immune checkpoint blockade in Immune Aging and its molecular mechanisms〇 Taeko Hayakawa, Akihiko Yoshimura
Department of Microbiology and Immunology, Keio University School of Medicine

WS11-18-P

Chromatin remodeling complex curtails the efficacy of PD-1 blockade in anti-cancer drug-resistant tumor〇 Masahiro Okada, Kanako Shimizu, Shin-Ichiro Fujii
Laboratory for Immunotherapy, RIKEN Center for Integrative Medical Sciences

WS11-19-P

Immunological contribution in the development of lung cancer with pulmonary fibrosis〇 Tatsuki Nishioka , Masahiro Kitabatake , Noriko Ouji-Sageshima , Takehiro Sakabe , Shigetp Hontsu ,Shigeo Muro2), Toshihiro Ito1)
1)

1)

1)

1)

2)

1)

Department of Immunology, Nara Medical University, 2)Department of Respirology, Nara Medical University

WS11-20-O/P

A TGF-β milieu molecule on Tregs orchestrates cancer progression in the lung
〇 Qiao Gou, Hiroyuki Takaba, Hiroshi Takayanagi
Department of Immunology, The University of Tokyo, Tokyo, Japan

WS11-21-P

Extrinsic and intrinsic inhibition of T cell response by co-inhibitory receptors, TIGIT and CD96
〇 Ann Hattori, Ei Wakamatsu, Hiroaki Machiyama, Ryuji Hashimoto, Hiroko Toyota, Masae Furuhata,
Hitoshi Nishijima, Arata Takeuchi, Tadashi Yokosuka
Tokyo Medical University

WS11-22-P

Immune response of B cells in tumor-draining lymph node
〇 Yasuhiro Kanda, Nanjun Li, Madoka Ozawa, Tomoya Katakai
Department of Immunology, Niigata University Graduate School of Medical and Dental Sciences, Niigata, Japan

WS11-23-O/P	Clonal expanded IgG-producing plasma cells triggered by Tfh cells are associated with better survival inendometrial cancer〇 Mayu Fujioka , Shusei Fujioka , Hiroyuki Yoshitomi , Masayo Ukita , Haruka Suzuki , Junzo Hamanishi ,Yasuhide Takeuchi3), Sachiko Minamiguchi3), Hiroaki Ito3), Masaki Mandai2), Hideki Ueno1)
1)

1)

1)

2)

2)

2)

1)

Department of Immunology, Kyoto University, Kyoto, Japan, 2)Department of Gynecology and Obstetrics, Kyoto University, Kyoto, Japan,
Department of Diagnostic Pathology, Kyoto University, Kyoto, Japan3)

WS11-24-P

Essential conditions for tumor-specific cell death by anti-pan-HLA class II mAb, mAb 4713
1, 2)
1, 3)
1)
〇 Takeshi Hirano , Shuji Matsuoka , Hideo Yagita
1)

Department of Immunological Diagnosis, Graduate School of Medicine, Juntendo University, 2)Department of Lactic Acid Bacteria Biological
Function Reseach, Graduate School of Medicine, Juntendo University, 3)Division of Cancer Immunotherapy, Exploratory Oncology Research andClinical Trial Center, National Cancer CenterWS11-25-P	Lymphocytosis correlates with hyperleukocytosis and favorable survival in childhood acute myeloblastic
leukemia: A complex pathogenetic role of lymphocytes〇 Bambang Ardianto, Christine Christine, Inggar Armytasari, Rina Triasih, Sri Mulatsih, Eddy Supriyadi,
Pudjo Hagung Widjajanto, Alexandra Widita Swipratami Pangarso, Ignatius Purwanto, Sutaryo Sutaryo
Department of Child Health, Faculty of Medicine, Public Health, and Nursing, Universitas Gadjah Mada/Dr. Sardjito General Hospital,
Yogyakarta, Indonesia

112WS11-26-P

	Chimeric antigen receptor binding affinity required for targeting the intracellular oncoprotein PRAME〇 Hiroyuki Hiratsuka, Yasushi Akahori, Hiroshi Shiku, Yoshihiro Miyahara, Hiroshi Fujiwara
Department of Personalized Cancer Immunotherapy, Mie University graduate School of medicine

December 8
WS12

Infection and Immunity II

WS12-01-P

SEPIVAC SWE™: an emulsion based adjuvant for prophylactic vaccines〇 Ko Sugahara, Célia Hérou, Hocine Nouari, Juliette Ben Arous
SEPPIC SA, Paris La Défense, La Garenne Colombes France

WS12-02-P

	Heterologous booster immunization with SARS-CoV-2 spike protein after mRNA vaccine elicits durable
and broad antibody responses〇 Tomohiro Takano, Ryutaro Kotaki, Saya Moriyama, Yu Adachi, Taishi Onodera, Kazutaka Terahara,
Masanori Isogawa, Takayuki Matsumura, Yoshimasa Takahashi
Research Center for Drug and Vaccine Development, National Institutes of Infectious Diseases

WS12-03-P

	Profiling antibody and autoantibody signatures after SARS-CoV-2 infection or COVID-19 vaccination withhigh-density peptide microarrays〇 Kirsten Heiss , Yuvaraj Mahendran , Fiordiligie Casilag , Renate Sekul , Volker Stadler
1)

1)

1)

1)

1)

2)

2)

Research and Development, PEPperPRINT GmbH, Heidelberg, Germany, Management, PEPperPRINT GmbH, Heidelberg, Germany

WS12-04-O/P

	Delayed antigen-specific CD4+ T-cell induction correlates with lower antibody responses and fewer
adverse effects to SARS-CoV-2 mRNA vaccination in older adults
1, 2)
1, 3)
〇 Norihide Jo , Yoko Hamazaki
1)

Department of Life Science Frontiers, Center for iPS Cell Research and Application (CiRA), Kyoto University, 2)Alliance Laboratory for
Advanced Medical Research, Graduate school of Medicine, Kyoto University, 3)Laboratory of Immunobiology, Graduate school of Medicine,
Kyoto University
WS12-05-P

Memory B-cell dynamics associated with evolution of SARS-CoV-2 neutralizing antibody〇 Taishi Onodera , Yu Adachi , Ryutaro Kotaki , Takeshi Inoue , Ryo Shinnakasu , Saya Moriyama ,Tomohiro Kurosaki2), Yoshimasa Takahashi1)
1)

1)

1)

2)

2)

1)

1)
Research Center for Drug and Vaccine Development, National Institute of Infectious Diseases, Japan, 2)Laboratory of Lymphocyte
Differentiation, WPI Immunology Frontier Research Center, Osaka University; Osaka, Japan

WS12-06-O/P

The underlying mechanism of the deterioration in obese patients with COVID-19
1, 2)
1, 2)
1, 2)
1)
1)
1, 2)
〇 Tadashi Hosoya , Seiya Oba , Yoji Komiya , Daisuke Kawata , Mari Kamiya , Hideyuki Iwai ,
2)
2)
2)
2)
3)
Sho Miyamoto , Takayuki Kanno , Akira Ainai , Tadaki Suzuki , Hideki Hasegawa , Shinsuke Yasuda1)
1)

Department of Rheumatology, Tokyo Medical and Dental University, 2)Department of Pathology, National Institute of Infectious Diseases,
Center for Influenza and Respiratory Virus Research, National Institute of Infectious Diseases

3)

WS12-07-O/P	Elevated Myl9 reflects the Myl9-containing microthrombi in SARS-CoV-2-induced lung exudative
vasculitis and predicts COVID-19 severity〇 Chiaki Iwamura, Kiyoshi Hirahara, Masahiro Nemoto, Kaori Tsuji, Miki Onoue, Akane Kurosugi, Atsuhi Sasaki,
Toshinori Nakayama
Chiba Univeristy

WS12-08-P

	Analysis of Fcγ receptor-mediated target-effector cells binding via influenza vaccine-induced antibodies
in a non-human primate model〇 Yuji Masuta , Shokichi Takahama , Takuto Nogimori , Saya Moriyama , Yoshimasa Takahashi ,Takuya Yamamoto1, 3, 4)
1)

1)

1)

2)

2)

1)
Laboratory of Immunosenescence, Center for Vaccine and Adjuvant Research, National Institutes of Biomedical Innovation, Health andNutrition, Osaka, Japan, 2)Research Center for Drug and Vaccine Development, National Institute of Infectious Diseases, Tokyo, Japan,
3)
Laboratory of Aging and Immune regulation, Graduate School of Pharmaceutical Sciences, Osaka University, Osaka, Japan, 4)Department of
Virology and Immunology, Graduate School of Medicine, Osaka University, Osaka, Japan113

WS12-09-P	An inactivated whole particle H5N1 vaccine confers protective antibody responses for 5 years incynomolgus monkeys〇 Misako Nakayama, Naoko Kitagawa, Hirohito Ishigaki, Thanh Cong Nguyen, Saori Suzuki, Hideaki Ishida,
Kazumasa Ogasawara, Yasushi Itoh
Department of Pathology, Shiga University of Medical Science - Otsu (Japan)

WS12-10-P

Characterization of mRNA contained lipid nanoparticle based liver-stage malaria vaccine
1)
1, 2)
3)
1)
1)
4)
〇 Sayuri Nakamae , Satoshi Miyagawa , Koki Ogawa , Jiun-Yu Jian , Mayumi Taniguchi , Takeshi Annoura ,Katsuyuki Yui5), Kenji Hirayama6), Shigeru Kawakami3), Shusaku Mizukami1, 6)
1)

Department of Immune Regulation, Shionogi Global Infectious Diseases Division, Institute of Tropical Medicine, Nagasaki University,
Nagasaki, Japan, 2)Laboratory for Drug Discovery and Disease Research, SHIONOGI & CO., LTD., Osaka, Japan, 3)Department of Pharmaceutical
Informatics, Graduate School of Biomedical Sciences, Nagasaki University, Nagasaki, Japan, 4)Department of Parasitology, National Institute of
Infectious Diseases, Tokyo, Japan, 5)Shionogi Global Infectious Diseases Division, Institute of Tropical Medicine, Nagasaki University, Nagasaki,
Japan, 6)School of Tropical Medicine and Global Health, Nagasaki University, Nagasaki, Japan
WS12-11-P	What determines the survival fate upon lethal viral infection? -properties and dynamics of circulating
immune cells〇 Riho Saito , Tomohiko Okazaki
1)

2)

1)

Laboratory of Molecular Biology, Graduate School of Pharmaceutical Sciences, The University of Tokyo, 2)​Laboratory of Molecular Cell Biology,
Institute for Genetic Medicine, Hokkaido University

WS12-12-O/P	The Vi capsular polysaccharide of Salmonella Typhi promotes macrophage phagocytosis by binding thehuman C-type lectin DC-SIGN
2)
2)
1, 2)
〇 Hirotaka Hiyoshi , Lillian F. Zhang , Andreas J. Bäumler
1)

Institute of Tropical Medicine, Nagasaki University, 2)University of California at Davis

WS12-13-P

	Translocation of prohibitin 2 in macrophages is inhibited by mycobacterial protein PE_PGRS30 resulting
in mitochondrial dysfunction and apoptosis〇 Kazunori Matsumura, Satoshi Takaki
Department of Immune Regulation, The Research Center for Hepatitis and Immunology, Research Institute, National Center for Global Healthand Medicine, Ichikawa, Chiba, Japan

WS12-14-P

Effect of Zmp1-deficient BCG vaccination in protective immunity to pulmonary tuberculosis〇 Masayuki Umemura
Goro Matsuzaki1, 2, 3)

1, 2, 3), Masayori Yoshisato1, 2), Ryusei Shimotada1, 2), Julia Toguchi1, 2), Giichi Takaesu1, 2, 3),

1)

Tropical Biosphere Research Center, University of the Ryukyus, Okinawa, Japan, 2)Department of Host Defense, Graduate School of Medicine,
University of the Ryukyus, Okinawa, Japan, 3)Advanced Medical Research Center, Faculty of Medicine, University of the Ryukyus, Okinawa, Japan

WS12-15-P

Immunological analysis of periodontal disease-induced cognitive disorders in mice
1)
1, 2)
1)
1)
1)
1)
〇 Sari Kishikawa , Jun-Ichi Nagao , Kenji Toyonaga , Emi Kaji , Kanae Negoro-Yasumatsu , Sonoko Tasaki ,1, 2)
Yoshihiko Tanaka
1)Section of Infection Biology, Department of Functional Bioscience, Fukuoka Dental College, Fukuoka, Japan, 2)Oral Medicine Research Center,
Fukuoka Dental College, Fukuoka, Japan

WS12-16-O/P

	The C-type lectin receptor Dcir1 counterbalances the antifungal response against Aspergillus fumigatus
infection〇 Fabio Yoshikawa, Shinobu Saijo
Medical Mycology Research Center, Chiba University, Chiba, Japan

WS12-17-P

	Modulation of host immune response by extracellular vesicles from parasitic nematode, Trichinella
spiralis〇 Sukhonthip Khueangchiangkhwang, Zhiliang Wu, Yoichi Maekawa
Department of Parasitology and Infectious Diseases, Gifu University Graduate School of Medicine

WS12-18-O/P

Transcriptomic analysis of the olfactory bulb during experimental cerebral malaria (ECM)
1, 2)
1, 3)
1, 2, 3)
〇 Julia Matsuo-Dapaah , Michelle Sue Jann Lee , Cevayir Coban

1)
Division of Malaria Immunology, Institute of Medical Science (IMSUT), University of Tokyo, 2)Graduate School of Medicine, University ofTokyo, 3)International Vaccine Design Center, Institute of Medical Science (IMSUT), University of Tokyo114

WS12-19-P

	Induction of Anisakis-specific IgE dependent on commensal bacteria in stomach during gastric Anisakis
infection〇 Chikako Shimokawa , Tadashi Takeuchi , Tamotsu Kato , Hiromu Sugiyama , Hiroshi Ohno , Hajime Hisaeda
1)

2)

2)

1)

1)

2)

1)

2)

Department of Parasitology, National Institute of Infectious Diseases, Laboratory for Intestinal Ecosystem, RIKEN Center for Integrative
Medical Sciences

WS12-20-O/P

	Identification of leukocyte immunoglobulin-like receptor A1 (LILRA1) as a specific receptor forAspergillus
fumigatus conidia〇 Yasunobu Miyake, Hiroki Yoshida
Division of Molecular and Cellular Immunoscience, Department of Biomolecular Sciences, Faculty of Medicine, Saga University

Theilovirus 3C protease cleaves innate immune sensor MDA5 to inhibit double-stranded RNA recognition

WS12-21-P〇 Akihiko Komuro , Masahiko Miyamoto , Toshiki Himeda , Takako Okuwa , Masaaki Nameta , Yutaka Yoshida ,Benyapa Chunhaphinyokul1), Nobuyuki Tanaka4), Masaya Higuchi2)
1)

1)

2)

2)

3)

3)

1)

Faculty of Pharmaceutical Sciences, Niigata University of Pharmacy and Applied Life Sciences, Niigata/Japan, 2)Kanazawa Medical University
School of Medicine, Ishikawa, Japan, 3)Niigata University, 4)Division of Tumor Immunology, Miyagi Cancer Center Research Institute, Miyagi/
Japan
WS12-22-P

	Riplet-mediated polyubiquitination of LGP2 modulate RIG-I activities to avoid excessive cytokine
expression during viral infection〇 Takahisa Kouwaki, Hiroyuki Oshiumi
Department of immunology, Graduate school of Medical Sciences, Kumamoto University

WS12-23-O/P

	Antiviral innate immune responses are regulated by a lipid metabolism via expression of unusual type I
IFN subtypes〇 Tasuku Nishimura, Takahisa Kouwaki, Hiroyuki Oshiumi
Department of Immunology, Faculty of Life Sciences, Kumamoto University, Kumamoto, Japan

WS12-24-P

Seeking an immunotherapy target for treating antimicrobial-resistant Staphylococcus aureus Infection〇 Kei Sakamoto , Yuko Tanishita , Akito Ariyoshi , Daisuke Sasaki , Katsunori Yanagihara , Gabriel Nuñez ,Hideki Hara2, 4)
1)

2)

1)

1)

1)

3)

1)
Department of Laboratory Medicine, Nagasaki University Graduate School of Biomedical Sciences, Nagasaki, Japan, 2)Department ofMicrobiology and Immunology, Keio University School of Medicine, Tokyo, Japan, 3)Department of Pathology and Rogal Cancer Center,
University of Michigan Medical School, MI, USA, 4)Department of Microbiology and Immunochemistry, Asahikawa Medical University,
Asahikawa, Japan

WS12-25-P

Physiological relevance of TRAF6 signaling in dendritic cells in controlling C. rodentium infection〇 Thanyakorn Chalalai , Naganori Kamiyama , Shimpei Ariki , Sotaro Ozaka , Nozomi Sachi , Yomei Kagoshima ,Ryu Okumura2), Kiyoshi Takeda2), Takashi Kobayashi1)
1)

1)

1)

1)

1)

1)

1)

Department of Infectious Disease Control, Faculty of Medicine, Oita University, Oita, Japan, 2)Department of Microbiology and Immunology,
Graduate School of Medicine, Osaka University, Suita, Osaka, Japan

December 8WS13

B cell Development and Activation

WS13-01-O/P

Transcriptional signature of anergy in naturally occurring self-reactive B cells
1, 2)
2)
2)
2)
〇 Ryosuke Hiwa , John P. Huizar , James L. Mueller , Julie Zikherman

1)
Department of Rheumatology and Clinical Immunology, Kyoto University Hospital, Kyoto, Japan, 2)Division of Rheumatology, Rosalind Russell
and Ephraim P. Engleman Arthritis Research Center, Department of Medicine, UCSF, San Francisco, CA, USA

WS13-02-P

Augmentation of auto-antibody production in Parm1-deficient NZB mice
〇 Sayaka Fukushima , Mizuki Ishikawa , Kagefumi Todo , Haruka Honda , Masaki Hikida
1)

1)

1)

2)

1)

1)

2)

Graduate School of Engineering Science, Akita University, Department of Health and Nutrition, Tokiwa University

WS13-03-O/P

Immunological functions of Castor1 in B cells
1)
1)
1, 2)
1)
〇 Takeshi Kusuda , Toshihiko Komai , Tomohisa Okamura , Keishi Fujio
1)

Department of Allergy and Rheumatology, Graduate School of Medicine, The University of Tokyo, 2)Department of Functional Genomics and
Immunological Diseases, Graduate School of Medicine, The University of Tokyo115

WS13-04-O/P

The COMMD3/8 complex is a potential therapeutic target for autoimmune diseases
1)
1, 2)
1, 2, 3)〇 Taiichiro Shirai , Akiko Nakai , Kazuhiro Suzuki

1)

Laboratory of Immune Response Dynamics, WPI Immunology Frontier Research Center, Osaka University, Suita, Osaka, Japan, 2)Department of
Immune Response Dynamics, Research Institute for Microbial Diseases, Osaka University, Suita, Osaka, Japan, 3)Center for Infectious Disease
Education and Research, Osaka University, Suita, Osaka, Japan
WS13-05-O/P

IL-15-producing splenic B cells play pathogenic roles in the development of autoimmune hepatitis
1, 2)
1)
1)
〇 Sota Fujimori , Nobuhiro Nakamoto , Takanori Kanai

1)

Division of Gastroenterology and Hepatology, Department of Internal Medicine, Keio University School of Medicine, 2)Research Unit
Immunology & Inflammation, Innovative Research Division, Mitsubishi Tanabe Pharma Corporation
WS13-06-O/P

Essential function for EMC1(ER membrane complex subunit1) in Ca2+ influx and B cell development〇 Kazuhiko Kawata , Chie Kikutake , Mikita Suyama , Yoshihiro Baba
1)

2)

2)

1)

1)

Division of Immunology and Genome Biology, Medical Institute of Bioregulation, Kyushu University, Fukuoka, Japan, 2)Division of
Bioinformatics, Medical Institute of Bioregulation, Kyushu University, Fukuoka, Japan

WS13-07-O/P

miR-195 accomplishes B cell development without EBF1 by regulating transcription factors〇 Yuji Miyatake , Tomokatsu Ikawa , Ken-Ichi Hirano , Katsuto Hozumi , Kiyoshi Ando , Hiroshi Kawamoto ,Ai Kotani1)
1)

2)

3)

3)

4)

5)

1)

Department of Advanced Medical Science, Tokai University School of Medicine, Isehara, Japan, 2)RIKEN Research Center for Allergy and
Immunology, Yokohama, Japan, 3)Department of Immunology, Tokai University School of Medicine, Isehara, Japan, 4)Department of Hematology,
Tokai University School of Medicine, Isehara, Japan, 5)Department of Immunology, Institute for Frontier Life and Medical Science, Kyoto
University, Kyoto, Japan
WS13-08-P

	bHLH transcription factor E2A and Ets-related gene Erg synergistically orchestrates B cell signature gene
expression through the regulation of enhancer activity〇 Reiko Hidaka, Kazuko Miyazaki, Hiroshi Kawamoto, Masaki Miyazaki
Kyoto University, Institute for Life and Medical Sciences, Department of Immunology

WS13-09-P

A novel subpopulation of B1 B cells whose secretion of natural antibodies is suppressed by complexin 2〇 Emi Tsuru , Hiroki Mogawa , Masaaki Mizobuchi , Masayuki Tsuda
1)

2)

2)

1)

1)

Institute for Laboratory Animal Research, Science Research Center, Kochi University, Kochi, Japan, 2)Equipment Support Planning Office, Kochi
University, Kochi, Japan

WS13-10-O/P

The mechanism for T cell-independent B cell activation by the bacterial polysaccharide dexstran
1, 2)
1)
1)
1)
1)
2)
〇 Yuming Huang , Kana Matsumura , Nazim Medzhidov , Toshitaro Takata , Miao Tang , Takeshi Tsubata
1)

Department of Immunology, Medical Research Institute, Tokyo Medical and Dental University., 2)Department of Pathology, Nihon University
School of DentistryWS13-11-O/P

The importance of IL-1 - IL-1 receptor signaling to T-cell-independent type 2 responses〇 Mari Tenno, Tang Xuyang, Takumi Umezu, Daisuke Kitamura
Division of Cancer Cell Biology, Research Institute for Biomedical Sciences (RIBS) Tokyo University of Science

WS13-12-P

DNase γ is required for T cell-independent type II immune response〇 Kei Kato , Kei Haniuda , Saori Fukao , Daisuke Kitamura
1)

2)

3)

1)

1)

Research Institute for Biomedical Sciences, Tokyo University of Science, Chiba, Japan, 2)Department of Immunology, University of Toronto,
Toronto, Canada, 3)Princess Margaret Cancer Centre, University Health Network, Toronto, Canada
WS13-13-O/P	Adjuvant Activity of Chemically Synthesized Alcaligenes Lipid A to Augment Immune Responses against
Haemophilus Influenzae Type B Conjugate Vaccine
1, 2)
1)
2)
1, 2)
1, 2)
2)
2)
〇 Zilai Liu , Koji Hosomi , Atsushi Shimoyama , Ken Yoshii , Xiao Sun , Haruki Yamaura , Davie Kenneth ,1)
1, 3)
4, 5, 6)2)
1, 2, 4, 7, 8)Azusa Saika , Takahiro Nagatake , Hiroshi Kiyono, Koichi Fukase , Jun Kunisawa
1)

National Institutes of Biomedical Innovation, Health, and Nutrition, Osaka, Japan, 2)Osaka University, Osaka, Japan, 3)Meiji University, Tokyo,
Japan, 4)The University of Tokyo, Tokyo, Japan, 5)University of California San Diego, California, United States, 6)Chiba University, Chiba, Japan,
7)
Kobe University, Hyōgo, Japan, 8)Waseda University, Tokyo, Japan
WS13-14-O/P

Recombinant anti-RP105 provides an adjuvant effect for gene immunization against influenza〇 Tatsuya Yamazaki, Mrityunjoy Biswas, Masanori Inui, Susumu Tomono, Sachiko Akashi-Takamura
Department of Microbiology and Immunology, Aichi Medical University, School of Medicine, Aichi, Japan116

B cell antigen receptors expressed on embryo-derived innate-like B cells

WS13-15-P〇 Yuhei Mizunoe , Aika Otaki , Keiko Fujisaki , Shogo Okazaki , Ryo Goitsuka
1)

1)

1)

2)

1)

1)

Division of Cell Fate Regulation, Research Institute for Biomedical Sciences, Tokyo University of Science, 2)Department of Microbiology, Nihon
University School of DentistryWS13-16-P

	Single-cell RNA-sequencing of the synovial cells in gp130F759, a murine rheumatoid arthritis model,
revealed changes in B-cell repertoire at the transitional phase from innate to acquired immunity〇 Katsuhiko Ishihara , Ayano Yahagi , Masanori Iseki
1)

2)

3)

1)

Department of Design for Medical and Health Care, Kawasaki University of Medical Welfare, 2)Microanatomy and Developmental Biology,
Tokyo Women’s Medical University,, 3)Department of Immunology and Molecular Genetics, Kawasaki Medical School
WS13-17-O/P	Evaluation of immune response induced by influenza vaccines using the repertoire analysis of variablegenes of antibodies〇 Hinako Ohkusa , Mizuki Uryu , Shinichi Fujihara , Kayoko Sato , Hideki Asanuma , Makoto Tsuiji
1)

1)

1)

2)

3)

1)

1)

2)

Department of Microbiology, Hoshi University School of Pharmacy and Pharmaceutical Sciences, Tokyo, Japan., Department of Virology 3,
National Institute of Infectious Diseases, Tokyo, 3)Center for Influenza and Respiratory Virus Research, National Institute of Infectious Diseases,
Tokyo, Japan

Characterization of VHHs from unique semi-synthetic alpaca VHH phage display library

WS13-18-P

1, 2)
2, 3)
1)
〇 Narutoshi Tsukahara , Akikazu Murakami , Hidehiro Kishimoto1)

Department of Immunology & Parasitology, Graduate School of Medicine, University of the Ryukyus, Okinawa, Japan, 2)RePHAGEN Co., Ltd.,
Okinawa, Japan, 3)Department of Oral Microbiology, Graduate School of Biomedical Sciences, Tokushima University, Tokushima, JapanThe analysis of anti-apoptotic effect in B cells by anti-RP105 mAb or TLR ligands

WS13-19-P〇 Sajid Iftekhar Chowdhury, Sachiko Akashi-Takamura
Department of Microbiology and Immunology, Aichi Medical University

December 8
WS14

Innate immunity (1) Innate inflammation and disease

WS14-01-P

	The complement receptor C5aR may control regulatory T cells via activation of dendritic cells in head andneck squamous cell carcinoma〇 Masaki Imai, Sayuri Yamazaki
Department of Immunology, Nagoya City University Graduate School of Medical Sciences, Nagoya, Japan

WS14-02-P

	Fusobacterium nucleatum infection activates the non-canonical inflammasome pathway to exacerbate
inflammatory response in acute colitis mice
〇 Kotchakorn Boonyaleka, Tokuju Okano, Toshihiko Suzuki
Graduate School of Medical and Dental Sciences, Tokyo Medical and Dental University

WS14-03-O/P

HMGB1 in cancer and inflammatory diseases〇 Hideyuki Yanai
Research Center for Advanced Science and Technology, The University of Tokyo

WS14-04-P

	Heat acclimation ameliorated heat stress-induced acute kidney injury by preserving the number ofresident macrophages in mice
〇 Hiroyasu Goto , Hiroyuki Nakashima , Seigo Ito , Kazuma Mori , Keiko Tanoue , Azusa Kato ,Masahiro Nakashima2), Naoki Oshima1), Manabu Kinoshita2)
1)

2)

3)

2)

1)

2)

1)

Department of Nephrology and Endocrinology, National Defense Medical College, Saitama, Japan, 2)Department of Immunology andMicrobiology, National Defense Medical College, Saitama, Japan, 3)Department of Internal Medicine, Self-Defense Force Iruma Hospital,
Saitama, Japan
WS14-05-P

	Optimal design of the plastic hollow microneedle: enable accurate dosing and Th1 response under
intradermal HBsAg vaccination〇 Natsumi Koike , Shintaro Onishi , Takatoshi Niitsu , Tomoya Nishimura , Shingo Kakuo , Takehiko Toujou ,Takuya Mori1)
1)

1)

2)

1)

2)

1)

Biological Science Research, Kao Corporation, Tochigi, Japan, 2)Processing Development Research, Kao Corporation, Tochigi, Japan

117

2)

WS14-06-O/P

Short-term epigenetic memory in monocytes induced by BNT162b2 mRNA vaccine〇 Yuta Yamaguchi, Yasuhiro Kato, Atsushi Kumanogoh
Department of Respiratory Medicine and Clinical Immunology, Osaka University Graduate School of Medicine, Suita, Japan

WS14-07-P	Circulating neutralizing IgM regulated by IL-13 protects against disseminated infection by Streptococcus
pneumoniae: comparative evaluation to organ-specific T1 response〇 Natsuo Yamamoto , Tsuyoshi Suzuki , Rie Zenda , Kiwamu Nakamura , Ken Iseki , Keiji Kanemitsu ,Philip Askenase3)
1)

2)

2)

1)

2)

1)

1)

Department of infection control, Fukushima Medical University, 2)Department of emergency and critical care medicine, Fukushima Medical
University, 3)Sect. Allerg. Immunol. Sch. of Med. Yale Univ.

WS14-08-P

Altered interaction between monocytes and platelets in preeclampsia〇 Mikako Nagashima, Yuji Takeda, Shinichi Saito, Saima Sabrina, Akemi Araki, Hironobu Asao
Department of Immunology, Yamagata University School of Medicine, Yamagata, Japan

WS14-09-O/P

Molecular mechanisms by which mTORC1 drives granulomas〇 Ryosuke Hiranuma, Ryota Sato, Kensuke Miyake
Division of Innate Immunity, Department of Microbiology and Immunology, The Institute of Medical Science, The University of Tokyo

WS14-10-P	1’-Acetoxychavicol acetate protects against LPS-induced lung injury and acetaminophen-induced acuteliver injury〇 Daisuke Ori, Guang Han Ong, Candra Trinugraha Afi, Taro Kawai
Division of Biological Science, Graduate School of Science and Technology, Nara Institute of Science and Technology, Ikoma, Japan

WS14-11-O/P

	Impact of changes of the gut microbiota on the development of liver inflammation and fibrosis in a novel
dietary mouse model of non-alcoholic steatohepatitis, “3-F mice”〇 Kaichi Kasai , Yukihiro Furusawa , Yuki Tada , Naoya Igarashi , Koichi Tsuneyama , Yoshinori Nagai
1)

1)

1)

1)

2)

1)

1)

2)

Department of Pharmaceutical Engineering, Faculty of Engineering, Toyama Prefectural University, Department of Pathology and Laboratory
Medicine, Tokushima University Graduate School
WS14-12-P

	Amelioration of inflammatory innate immune responses by a high-molecular weight sulfatedpolysaccharide Fucoidan
1, 2)
1)
3)
4)
5)
〇 Yoshiyuki Miyazaki , Toshiya Satoyama , Hayato Nakano , Shugo Takeuchi , Hideaki Takeuchi ,2, 6)Daisuke Tachikawa
1)

Faculty of Agriculture, Kyushu University, Fukuoka, Japan, 2)NPO Research Institute of Fucoidan, Fukuoka, Japan, 3)Ventuno Co., LTD.,
Fukuoka, Japan, 4)Kaisou-science no kai Co., LTD., Tokyo, Japan, 5)Kamerycah Inc., CA, United States, 6)Wakamiya Hospital, Oita, Japan

WS14-13-O/P	Direct activation of microglia by β-glucosylceramide causes phagoptosis of neurons that aggravates
Gaucher disease
1, 2)
1)
1, 2)
〇 Takashi Shimizu , Charles Schutt , Sho Yamasaki
1)

Department of Molecular Immunology, Research Institute for Microbial Diseases, Osaka University, Osaka, Japan, 2)Laboratory of Molecular
Immunology, Immunology Frontier Research Center, Osaka University, Osaka, Japan
WS14-14-O/P

Novel lipid metabolism prevents inflammation for neural repair after ischemic stroke
1, 2)
2)
3)
2)
〇 Akari Nakamura , Seiichiro Sakai , Makoto Murakami , Takashi Shichita
1)

Graduate School of Medical and Dental Sciences, Tokyo Medical and Dental University, Tokyo, Japan, 2)Stroke Renaissance Project, Tokyo
Metropolitan Institute of Medical Science, Tokyo, Japan, 3)Laboratory of Microenvironmental and Metabolic Health Science, Center for Disease
Biology and Integrative Medicine, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan
WS14-15-O/P

Modeling bleomycin-induced lung injury using primary murine cell-derived lung organoids〇 Bin Wu, Shigeyuki Shichino, Satoshi Ueha, Kouji Matsushima
Division of molecular regulation of inflammatory and immune diseases, Institution of Biomedical Research, Tokyo University of Science

WS14-16-P

Direct effects of monosodium urate crystal on human endothelial cells in hyperuricemia〇 Motokazu Tsuneto , Yuka Katsukura , Naruomi Yamada , Akika Fukawa , Ichiro Hisatome
1)

2)

2)

1)

2)

1)

2)

Division of regenerative medicine and therapeutics, Department of medicine, Tottori university, Food Microbiology and Function ResearchLaboratories, R&D Division, Meiji Co., Ltd.

118

Inflammasome Activation is Regulated by Fever stress-dependent Integrity of Centrosome

WS14-17-P

1)
1, 2)
1)
〇 Riku Saito , Hideki Hara , Akihiko Yoshimura

1)
Department of Microbiology and Immunology, Keio University School of Medicine, Tokyo, Japan, 2)Department of Microbiology and
Immunochemistry, Asahikawa Medical University, Hokkaido, Japan

Analysis of metabolic reprogramming in macrophages utilizing genome-wide CRISPR screening

WS14-18-P〇 Shota Yasukura , Masanori Yoshinaga , Michael C Bassik , Osamu Takeuchi
1)

1)

2)

1)

1)

Department of Medical Chemistry, Kyoto University Graduate School of Medicine, Kyoto, Japan, 2)Department of Genetics, Bassik Lab, Stanford
University School of Medicine, Stanford CA, USA

December 8
WS15

Autoimmune diseases -Systemic-

WS15-01-O/P

	SLE stratification based on BAFF and IFN-I bioactivity for biologics and implications of BAFF produced byglomeruli in lupus nephritis〇 Eri Itotagawa, Takehiro Hirayama, Tatsunori Jo, Kohei Tsujimoto, Yasuhiro Kato, Hyota Takamatsu,
Atsushi Kumanogoh
Department of Respiratory Medicine and Clinical Immunology, Graduate School of Medicine, Osaka University, Japan

WS15-02-O/P	Transforming growth factor-β3 in the differentiation and function of T peripheral helper cells and its
relationship to disease activity in patients with systemic lupus erythematosus〇 Yu Shan
The First Department of Internal Medicine, School of Medicine, University of Occupational and Environmental Health, Japan, Kitakyushu, Japan

WS15-03-O/P

	DOCK8-expressing T follicular helper cells newly generated beyond self-organized criticality cause
systemic lupus erythematosus (SLE)
1, 2, 3)
, Ken Tsumiyama1, 2, 3), Yumi Miyazaki1, 2), Kenichi Uto2), Keiichi Sakurai1, 3),〇 Shunichi Shiozawa
1)Takahiko Horiuchi , Tsukasa Matsubara3, 3), Takashi Yamane4), Yohei Mukai5), Takuji Enya6), Masaaki Miyazawa6),
Kazuko Shiozawa7)
1)

Kyushu University Beppu Hospital, Beppu, Japan, 2)Kobe University, Kobe, Japan, 3)Institute for Rheumatic Diseases, Kato-shi, Japan,
Kakogawa Central City Hospital, Kakogawa, Japan, 5)KAN Research Institute, Inc., Kobe, Japan, 6)Department of Immunology, Kindai University,
Osaka-Sayama, Osaka, Japan, 7)Hyogo Prefectural Kakogawa Medical Center, Kakogawa, Japan4)

WS15-04-O/P

Vorinostat ameliorates the onset and severity of SLE prone mice by inhibiting IFN-I production
1, 2)
3)
4)
1, 2)
1, 2, 5, 6)〇 Takehiro Hirayama , Daiki Nagira , Hachiro Konaka , Hyota Takamatsu , Atsushi Kumanogoh

1)
Department of Respiratory Medicine and Clinical Immunology, Graduate School of Medicine, Osaka University, 2)Department of
Immunopathology, WPI, Immunology Frontier Research Center (iFReC), Osaka University, 3)Graduate School of Medicine, Osaka University,
4)
Department of internal medicine, Nippon life Hospital, 5)Center for Infectious Disease Education and Research (CiDER), Osaka University,
6)
Integrated Frontier Research for Medical Science Division, Institute for Open and Transdisciplinary Research Initiatives

WS15-05-O/P

Pathogenic neuropsychiatric effect of stress-induced microglial interleukin 12/23 axis in SLE〇 Yuki Tanaka

1, 2, 3)

, Nobuya Abe1, 4), Masato Tarumi1, 4), Rie Hasebe1, 2, 3), Tatsuya Atsumi4), Masaaki Murakami1, 2, 3)

1)

Division of Molecular Psychoimmunology, Institute for Genetic Medicine, Graduate School of Medicine, Hokkaido University, Sapporo, Japan,
National Institutes for Quantum and Radiological Science and Technology, Quantum Immunology, 3)Division of Molecular Neuroimmunoloy,
Department of Homeostatic Regulation, National Institute for Physiological Sciences, National Institutes of Natural Sciences, 4)Department ofRheumatology, Endocrinology and Nephrology, Faculty of Medicine and Graduate School of Medicine, Hokkaido University, Sapporo, Japan2)

WS15-06-O/P

	CD153+ CD4+ T cells exacerbate the autoimmune pathology via the interaction with CD30+ cells in salivary
glands in Sjögren's syndrome
1, 2)
1)
1)
2)
2)
3)
〇 Kunihiro Otsuka , Hiroyuki Kondo , Shin-Ichi Tsukumo , Rieko Arakaki , Mami Sato , Hideo Yagita ,2)
1)
Naozumi Ishimaru , Koji Yasutomo
1)
Department of Immunology and Parasitology, Tokushima University Graduate School of Medicine, 2)Department of Oral Molecular Pathology,
Tokushima University Graduate School of Medicine, 3)Department of Immunology, Juntendo University School of Medicine

WS15-07-O/P

Role of Mucin 19 in Pathogenesis of a Mouse Model for Sjögren's Syndrome〇 Yuki Kawahito, Kai Tamura, Mami Sato, Kunihiro Otsuka, Takaaki Tsunematsu, Naozumi Ishimaru
Department of Oral Molecular Pathology, Tokushima University School of Dentistry, Tokushima, Japan119

WS15-08-O/P

Synovial phenotyping in Japanese RA patients using ultrasound-guided needle biopsy〇 Risa Yoshihara , Haruka Tsuchiya , Yasunori Omata , Haruka Takahashi , Akihiro Uchio , Yuji Maenohara ,Takumi Matsumoto2), Hiroaki Harada1), Hirofumi Shoda1), Sakae Tanaka2), Tomohisa Okamura3), Keishi Fujio1)
1)

1)

2)

1)

2)

2)

1)

Department of Allergy and Rheumatology, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan, 2)Department of Orthopaedic
Surgery, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan, 3)Department of Functional Genomics and Immunological
Diseases, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan
WS15-09-O/P

	Differential TCR repertoire for joint self-antigens determines the functional balance between theregulatory T and arthritogenic T cells in T cell-mediated autoimmune arthritis
1, 2)
1)
1)
1)
2)
1)
〇 Yusuke Takeuchi , Daiya Ohara , Hitomi Watanabe , Gen Kondoh , Akio Morinobu , Keiji Hirota
1)

Laboratory of Integrative Biological Science, Institute for Life and Medical Sciences, Kyoto University, Kyoto, Japan, 2)Department ofRheumatology and Clinical Immunology, Graduate School of Medicine, Kyoto University, Kyoto, Japan

WS15-10-P	Pathophysiological analysis of arthritis in Inter alpha trypsin inhibitor heavy chain 4 (ITIH4)-deficient mice
〇 Tamaki Iwai, Ayako Ohyama, Taihei Nishiyama, Yuya Kondo, Hiroto Tsuboi, Isao Matsumoto
Department of Rheumatology, Faculty of Medicine, University of Tsukuba

WS15-11-P

	Pathogenetic role of IFNγ producing T cells in lupus model mice induced by Toll-like receptor 7 agonist
imiquimod〇 Reona Tanimura, Yuya Kondo, Masaru Shimizu, Ryota Sato, Hiroto Tsuboi, Takayuki Sumida, Isao Matsumoto
Department of Rheumatology, Faculty of Medicine, University of Tsukuba

WS15-12-P

The analysis of immunological features of plasma cells in SLE model mice, MRL/lpr〇 Emi Minegishi , Yuki Tanaka , Keiko Yoshimoto , Yumi Ikeda , Kotaro Otomo , Katsuya Suzuki ,Tsutomu Takeuchi2), Yuko Kaneko2)
1)

2)

1)

2)

2)

2)

1)

Keio University School of Medicine, 2)Division of Rheumatology, Department of Internal Medicine, Keio University School of Medicine

WS15-13-P

The analysis of immunological features of regulatory T cells in MRL/lpr, a mouse model of SLE〇 Yuki Tanaka
Keio University School of Medicine, Tokyo, Japan

WS15-14-P

	IL-21 receptor induced via glycolysis in naïve B cells and its potential as a trigger for exacerbation of
disease activity in SLE
1)
1)
1)
1)
1, 2)
〇 Masanobu Ueno , Shigeru Iwata , Yasuyuki Todoroki , Kaoru Yamagata , Koshiro Sonomoto ,
1)
1)
1)
1)
1)
Kentaro Hanami , Yusuke Miyazaki , Hiroko Miyata , Atsushi Nagayasu , Ryuichiro Kanda , Shingo Nakayamada1),
Yoshiya Tanaka1)
1)

The First Department of Internal Medicine, School of Medicine, University of Occupational and Environmental Health, Japan, 2)Department ofClinical Nursing, University of Occupational and Environmental Health, Japan

WS15-15-P

Analysis of patrolling monocytes that induce lupus nephritis〇 Reika Tanaka
Division of Innate Immunity, Department of Microbiology and Immunology, The Institute of Medical Science, The University of Tokyo

WS15-16-P

Alteration of Tph/Treg and Th17/Treg balance in SLE patients by belimumab〇 Shinji Maeda, Shuntaro Isogai, Shin-Ya Tamechika, Tomoyo Maeda, Taio Naniwa, Akio Niimi
Department of Respiratory Medicine, Allergy and Clinical Immunology, Nagoya City University Graduate School of Medical Sciences, Nagoya, Japan

WS15-17-P	Identification of a novel autoantibody which facilitates T cell-mediated Sjogren’s syndrome likesialadenitis
1)
2, 3)
4)
4)
1)
〇 Mana Iizuka , Satoru Takahashi , Isao Matsumoto , Takayuki Sumida , Akihiko Yoshimura

1)
Department of Microbiology and Immunology, Keio University School of Medicine, 2)Department of Anatomy and Embryology, Faculty of
Medicine, University of Tsukuba, 3)Laboratory Animal Resource Center, University of Tsukuba, 4)Department of Internal Medicine, Faculty of
Medicine, University of Tsukuba

WS15-18-P

Pathological analysis of nasal tissue in a murine model of Sjögren’s syndrome〇 Tamura Kai, Yuki Kawahito, Mami Sato, Kunihiro Otsuka, Takaaki Tsunematsu, Naozumi Ishimaru
Department of Oral Molecular Pathology,​Tokushima University School of Dentistry,Tokushima,Japan120

WS15-19-P

	IL-26 facilitates cartilage destruction and infiltration of inflammatory cells into synovium in a collageninduced arthritis model〇 Yuki Shirakawa , Ryo Hatano , Takumi Itoh , Haruna Otsuka , Ko Okumura , Chikao Morimoto
1)

1)

1)

1)

2)

1)

1)

Department of Therapy Development and Innovation for Immune Disorders and Cancers, Graduate School of Medicine, Juntendo University,
Tokyo, Japan, 2)Atopy (Allergy) Research Center, Graduate School of Medicine, Juntendo University, Tokyo, Japan
WS15-20-P	Investigation of the source, therapeutic response and clinical significance of citrullinated ITIH4 inautoimmune arthritis〇 Ayako Ohyama, Tamaki Iwai, Taihei Nishiyama, Hiroto Tsuboi, Yuya Kondo, Isao Matsumoto
Department of Rheumatology, Faculty of Medicine, University of Tsukuba

December 8
WS16Tolerance and Immune suppression-1

WS16-01-O/P

	The Foxp3A384T mutation impairs TCR-induced proliferation of effector regulatory T cells by interfering with
c-Myc induction〇 Suzu Kawagoe, Maori Oda, Ryuichi Murakami, Shohei Hori
Laboratory of Immunology and Microbiology, Graduate School of Pharmaceutical Sciences, The University of Tokyo

WS16-02-O/P	The exon 5 of Ikzf1 is required for Foxp3-dependent gene suppression to maintain the homeostasis ofregulatory T cells〇 Kenji Ichiyama, Shimon Sakaguchi
Immunology Frontier Research Center (IFReC), Osaka University, Japan

WS16-03-P

	Foxp3-transduced T cells acquire regulatory T cell-like epigenome, gene expression, and suppressive
activity in vivo
〇 Yuxi Wei, Shotaro Funatsu, Ryuichi Murakami, Akira Nakajima, Shohei Hori
Laboratory for Immunology and Microbiology, Graduated School of Pharmaceutical Sciences, The University of Tokyo

WS16-04-O/P

	Antigen-specific stimulation induced peripherally derived Treg cells which establish Treg-specificepigenome and orchestrate oral tolerance
1)
1, 2)
1)
1)
1, 2)
〇 Masaya Arai , Ryoji Kawakami , Norihisa Mikami , Yamami Nakamura , Shimon Sakaguchi
1)

Department of Experimental Immunology, Immunology Frontier Research Center (IFReC), Osaka University, Osaka, Japan, 2)Department ofExperimental Immunology, Institute for Life and Medical Sciences, Kyoto university, Kyoto, Japan
WS16-05-O/P

	
Tonic TCR and IL-1b signaling mediate momentary and durable phenotypic alterations in naive CD4+ T cells〇 Takashi Sekiya
Department of Immune Regulation, National Center for Global Health and Medicine, Ichikawa, Chiba, Japan

WS16-06-O/P

Identification of a novel intestinal dendritic cell subset drives Rorgt+ Treg differentiation〇 Chengcheng Zou, Ichiro Taniuchi
Laboratory for Transcriptional Regulation, RIKEN Center for Integrative Medical Sciences

WS16-07-O/P

Development of the tolerogenic nanoparticle to induce antigen-specific regulatory T cells〇 Hiroki Toriumi , Li Shunyi , Daisuke Takahashi , Takanatsu Hosokawa , Liu Yiwei , Yusuke Kinashi ,Seiga Komiyama1), Takeshi Mori2), Koji Hase1)
1)

2)

1)

1)

2)

2)

1)

Division of Biochemistry, Graduate School of Pharmaceutical Science, Keio University, Tokyo, Japan, 2)Department of Applied Chemistry,
Faculty of Engineering, Kyushu University, Fukuoka, Japan121

WS16-08-O/P	Benign and harmful autoimmunity by manipulating the binding stability of self-peptides that influence thekinetics of tissue antigen-specific effector regulatory T cells
1, 2)
3)
4)
5)
6)
〇 Youwei Lin , Shun Sakuraba , Chandirasegaran Massilamany , Jayagopala Reddy , Yoshimasa Tanaka ,7)
1)
Sachiko Miyake , Takashi Yamamura
1)
Department of Immunology, National Institute of Neuroscience, National Center of Neurology and Psychiatry, Tokyo, JAPAN, 2)Departmentof Neurology, National Center Hospital, National Center of Neurology and Psychiatry, Japan, 3)National Institutes for Quantum Scienceand Technology, Institute for Quantum Life Science, Kyoto, Japan, 4)Immuno-oncology CRISPR Therapeutics, Cambridge, USA, 5)Schoolof Veterinary Medicine and Biomedical Sciences, University of Nebraska-Lincoln, Lincoln, USA, 6)Nagasaki University Graduate School of
Biomedical Science, Nagasaki, Japan, 7)Department of Immunology, Juntendo University School of Medicine, Tokyo, Japan

WS16-09-O/P

TRIM28 mediated Treg function underlies suppressive tumor immune environment〇 Hodaka Hayabuchi, Shunsuke Chikuma
Dept of Microbiology and Immunology, School of Medicine, Keio University, Tokyo, Japan

WS16-10-P	Suppressive function in TIGIT+ iTreg cells is serially transmitted into new stimulated T cells via CD 155
signaling with recall of TIGIT expression
1, 2)
3)
4)
2)
2)
2)
〇 Naoko Negishi , Koichiro Uchida , Kazuko Shibuya , Jiro Kitaura , Ko Okunura , Sonoko Habu

1)
Department of Indoor Environment Neurophysiological Research, Juntendo University Graduate School of Medicine, Tokyo, Japan., 2)Atopy
Research Center, Juntendo University Graduate School of Medicine, Tokyo, Japan., 3)Juntendo Advanced Research Institute for Health Science,
Juntendo University School of Medicine, Tokyo, Japan., 4)Department of Immunology, Faculty of Medicine, University of Tsukuba, Tsukuba, Japan

WS16-11-P

Expression and function of sialyl Lewis X glycans on mouse regulatory T cells〇 Kanae Ohishi, Shogo Nishida, Asaki Ishikura, Hiroko Nakatsukasa, Hirohito Abo, Hiroto Kawashima
Laboratory of Microbiology and Immunology, Graduate School of Pharmaceutical Sciences, Chiba University, Chiba, Japan

WS16-12-O/P

The effect of Oxytocin on ischemic resistance in recurrence of stroke〇 Ako Matsui, Yoshihiro Harada, Minako Ito
Division of Allergy and Immunology, Medical Institute of Bioregulation, Kyushu University, Fukuoka, Japan

WS16-13-P

	The role of regulatory T cells and dendritic cells in controlling the tumor microenvironment of humanhead and neck squamous cell carcinoma
1, 2)
1)
1, 2)
3, 4)
1)
〇 Kiyoshi Minohara , Masaki Imai , Takuma Matoba , James Badger Wing , Hiroaki Shime ,1)
1, 5, 6)
7)
8, 9)
8)
Mizuyu Odanaka , Ryuta Uraki, Akimichi Morita , Naganari Ohkura , Shimon Sakaguchi , Sayuri Yamazaki1)
1)
Department of Immunology, Nagoya City University Graduate School of Medical Sciences, Nagoya, Japan, 2)Department of Oto-rhinolaryngology and Head-and-neck-surgery, Nagoya City University Graduate School of Medical Sciences, Nagoya, Japan, 3)Laboratory of
Human Immunology (Single Cell Immunology), Immunology Frontier Research Center, Osaka University, Osaka, Japan., 4)Human Single Cell
Immunology Team, Center for Infectious Disease Education and Research (CiDER), Osaka University, Osaka, Japan., 5)Division of Virology,
Institute of Medical Science, University of Tokyo, Tokyo, Japan., 6)The Research Centerfor Global Viral Diseases, National Center for Global
Health and Medicine Research Institute, Tokyo, Japan., 7)Department of Geriatric and Environmental Dermatology, Nagoya City University
Graduate School of Medical Sciences, Nagoya, Japan, 8)Department of Experimental Immunology, World Premier International Research Center
Initiative, Immunology Frontier Research Center, Osaka University, Osaka, Japan, 9)Department of Frontier Research in Tumor Immunology,
Center of Medical Innovation and Translational Research, Graduate School of Medicine, Osaka University, Osaka, Japan

WS16-14-P

The survival factors of GATA3+ Tregs in the convalescence stage of glomerulonephritis〇 Ryota Sakai, Mariko Toguchi, Koichi Amano
Saitama Medical Center, Saitama Medical University, Saitama, Japan

WS16-15-O/P	An anti-CD22 antibody that expands regulatory B cells inhibits development of type 1 diabetes andallograft rejection in mouse models〇 Wang Long , Shinji Kunitake , Ayaka Endo , Koji Atarashi , Takeshi Tsubata
1)

2)

2)

1)

3)

1)

Pathology Department, Nihon University School of Dentistry, Immunology Department of Tokyo Medical and Dental University, 3)Departmentof Microbiology and Immunology, School of Medicine, Keio University

WS16-16-P

2)

Spatially heterogeneous immune regulations by resident macrophages in the liver〇 Yu Miyamoto, Junichi Kikuta, Masaru Ishii
Department of Immunology and Cell Biology, Osaka University Graduate School of Medicine, Osaka, Japan

WS16-17-P

FoxO1 suppresses IL-27-induced Tr1 cell differentiation〇 Shigenori Nagai, Miyuki Azuma
Graduate School of Medical and Dental Sciences, Tokyo Medical and Dental University, Tokyo, Japan

122

Single cell suppression profiling of human regulatory T cells

WS16-18-P

1)
1)
2)
3, 4)
1, 2)
〇 Jonas Søndergaard , Janyerkye Tulyeu , David Priest , Shimon Sakaguchi , James Wing

1)
Human Immunology Team, Center for Infectious Disease Education and Research (CIDER), Osaka University, Suita, Japan, 2)Laboratory of
Human Immunology (Single Cell Immunology), WPI Immunology Frontier Research Center (IFReC), Osaka University, Suita, Japan,
3)
Laboratory of Experimental Immunology, WPI Immunology Frontier Research Center (IFReC), Osaka University, Suita, Japan, 4)Department ofExperimental Pathology, Institute for Frontier Medical Sciences, Kyoto University, Kyoto, Japan

WS16-19-P

	Co-operative but distinct role of medullary thymic epithelial cells and dendritic cells in the production ofTregs in the thymus〇 Junko Morimoto , Minoru Matsumoto , Mitsuru Matsumoto
1)

2)

1)

1)

Division of Molecular Immunology, Institute for Enzyme Research, Tokushima University, Tokushima, Japan, 2)Department of MolecularPathology, Tokushima University Graduate School of Biomedical Sciences, Tokushima, Japan

December 8
WS17

Cytokines and Chemokines-1

WS17-01-O/P

DUSP3 regulates the STAT3-mediated signaling pathways〇 Yuichi Sekine , Kenji Oritani , Tadashi Matsuda
1)

2)

3)

1)

Kyoto Pharmaceutical University, 2)International University of Health and Welfare, 3)Hokkaido University

WS17-02-P

Functional role of STAP-2 in pathogenesis of idiopathic pulmonary fibrosis〇 Fuki Kobayashi , Jun-Ichi Kashiwakura , Kenji Oritani , Tadashi Matsuda
3)

2)

1)

1)

1)

Department of Immunology, Graduate School of Pharmaceutical Sciences, Hokkaido University, Hokkaido, Japan, 2)Department of Life Science,
Faculty of Pharmaceutical Sciences, Hokkaido University of Science, Hokkaido, Japan, 3)Department of Hematology, International University of
Health and Welfare, Tochigi, Japan
WS17-03-O/P

The role of TRAF5 in TLR2 expressed by B- and T-lymphocytes and macrophages〇 Mitsuki Azuma , Hiroaki Saito , Koyo Iwatani , Wakana Imai , Masashi Morita , Naoto Ishii , Takanori So
1)

1)

1)

1)

1)

2)

1)

1)

Laboratory of Molecular Cell Biology, Graduate School of Medicine and Pharmaceutical Sciences, University of Toyama, Toyama, Japan,
Department of Microbiology and Immunology, Tohoku University Graduate School of Medicine, Sendai, Japan2)

WS17-04-P

TAK1 limits death receptor Fas-induced proinflammatory cell death in macrophages〇 Kengo Maeda, Shinsuke Taki, Hideki Sanjo
Department of Molecular and Cellular Immunology, Shinshu University School of Medicine, Nagano, Japan

WS17-05-O/P

Anti-inflammatory effects of novel NF-κB inhibitory compounds in two inflammatory animal models〇 Hiroyuki Baba , Tadashi Hosoya , Yuma Kondo , Ryosuke Ishida , Saki Hatsuzawa , Hiroyuki Kagechika ,Shinsuke Yasuda1)
1)

1)

1)

2)

2)

2)

1)

Department of Rheumatology, Graduate School of Medical and Dental Sciences, Tokyo Medical and Dental University (TMDU), Tokyo, Japan,
Institute of Biomaterials and Bioengineering, Tokyo Medical and Dental University (TMDU), Tokyo, Japan2)

WS17-06-O/P

Mechanisms of pathogenesis induced by autoimmune disease-associated gene C8orf13
1, 2)
1, 3)
2)
3)
1)
〇 Shintaro Hojyo , Shuhei Shimoyama , Yuki Tanaka , Tatsuya Atsumi , Daisuke Kamimura ,1, 2, 4)Masaaki Murakami
1)
Molecular Psychoimmunology, Institute for Genetic Medicine, Hokkaido University, Sapporo, Japan, 2)Group of Quantum Immunology,
Institute for Quantum Life Science, National Institute for Quantum and Radiological Science and Technology, Inage, Japan, 3)Department ofRheumatology, Endocrinology and Nephrology, Faculty of Medicine and Graduate School of Medicine, Hokkaido University, Sapporo, Japan,
4)
Division of Molecular Neuroimmunology, National Institute for Physiological Sciences, National Institute of Natural Sciences, Okazaki, Japan

WS17-07-P

Placental ACKR3 regulates hematopoietic stem cells in offspring by scavenging mother-derived CXCL12〇 Ayumi Fukuoka, Gillian Wilson, Marieke Pingen, Gerard Graham
Chemokine Research Group, Institute of Infection, Immunity and Inflammation, University of Glasgow, UK

WS17-08-O/P	Innate immune responses triggered by CpG DNA-CXCL14 complex is mediated by Immunogloblinsuperfamily proteins
1, 2)
2)
1, 2, 3)〇 Risa Saito , Kosuke Tanegashima , Takahiko Hara
1)

Grad. Sch. of Tokyo Medical and Dental Univ., 2)Stem Cell Project, Tokyo Metropol. Inst. Med. Sci., 3)Grad. Sch. Tokyo Metropol. Univ.

123Rap1 facilitates cell polarization via RhoA signaling in T cells

WS17-09-O/P〇 Yoshihiro Ueda , Koichiro Higasa , Yuji Kamioka , Naoyuki Kondo , Shunsuke Horitani , Yoshiki Ikeda ,Takataro Fukuhara3), Yoshinori Fukui4), Tatsuo Kinashi1)
1)

2)

1)

1)

3)

1)

1)

The Department of Molecular Genetics, Institute of Biomedical Science, Kansai Medical University, 2)The Department of Genome Analysis,
Institute of Biomedical Science, Kansai Medical University, 3)Division of Gastroenterology and Hepatology, the Third Department of Internal
Medicine, Kansai Medical University, 4)Department of Immunobiology and Neuroscience, Medical Institute of Bioregulation, Kyushu University
WS17-10-O/P

	Crosstalk between the β2-adrenergic receptor and chemokine receptors in lymphocyte recirculation
through lymph nodes
1, 2)
1, 2, 3)
〇 Akiko Nakai , Kazuhiro Suzuki

1)
Laboratory of Immune Response Dynamics, WPI Immunology Frontier Research Center, Osaka University, Osaka, Japan., 2)Department of
Immune Response Dynamics, Research Institute for Microbial Diseases, Osaka University, Osaka, Japan., 3)Center for Infectious Disease
Education and Research, Osaka University

Ligand-independent function of β2-adrenergic receptor affects IgE-mediated Ca2+-influx in mast cells

WS17-11-O/P

1, 2)
1, 2)
1)
1)
2)
1, 2)
〇 Kei Nagao , Yuki Fujita , Hitoshi Urakami , Atsunori Kamiya , Sachiko Miyake , Soichiro Yoshikawa

1)

Department of Cellular Physiology, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, 2)Department of
Immunology, Juntendo University School of Medicine

Extracellular DJ-1 has a essential role in the induction of sterile inflammation after ischemic stroke

WS17-12-O/P

1, 2)
2)
2)
〇 Koutarou Nakamura , Ryuki Koyama , Takashi Shichita
1)

Graduate School of Frontier Sciences, The University of Tokyo, Tokyo, JAPAN, 2)Stroke Renaissance Project, Tokyo Metropolitan Institute ofMedical Science, Tokyo, Japan

WS17-13-O/P	Conditioned medium of immortalized stem cells from human exfoliated deciduous tooth exhibit protective
effect on the peripheral neuropathy of experimental autoimmune neuritis〇 Eri Sakamoto , Hideaki Hasegawa , Aruma Watanabe , Yasuhiro Katahira , Satomi Miyakawa , Izuru Mizoguchi ,Takayuki Yoshimoto7)
1)

2)

3)

4)

5)

6)

1)
Department of Immunoregulation, Institute of Medical Science, Tokyo Medical University, Tokyo, Japan, 2)Department of Immunoregulation,
Institute of Medical Science, Tokyo Medical University, Tokyo, Japan, 3)Department of Immunoregulation, Institute of Medical Science, Tokyo
Medical University, Tokyo, Japan, 4)Department of Immunoregulation, Institute of Medical Science, Tokyo Medical University, Tokyo, Japan,
5)
Department of Immunoregulation, Institute of Medical Science, Tokyo Medical University, Tokyo, Japan, 6)Department of Immunoregulation,
Institute of Medical Science, Tokyo Medical University, Tokyo, Japan, 7)Department of Immunoregulation, Institute of Medical Science, Tokyo
Medical University, Tokyo, Japan

WS17-14-P

Mesenchymal stromal cells regulate epithelial stem cell metabolism in the colon by producing CXCL12〇 Mayu Yagita , Hisako Kayama , Takashi Nagasawa , Atsushi Kumanogoh , Kiyoshi Takeda
1)

2)

3)

1)

2)

1)

Department of Respiratory Medicine, Clinical Immunology, Graduate School of Medicine, Osaka University, Suita, Japan., 2)Laboratory of
Immune Regulation, Department of Microbiology and Immunology, Graduate School of Medicine, Osaka University, Osaka, Japan, 3)Laboratoryof Stem Cell Biology and Developmental Immunology, Graduate School of Frontier Biosciences, Osaka University, Suita, Japan
WS17-15-P

Oncostatin M receptor β mediates skin wound healing by promoting fibroblast accumulation and function〇 Yuko Ishida , Yumi Kuninaka , Tadasuke Komori , Mizuho Nosaka , Akihiko Kimura , Atsushi Miyajima ,Yoshihiro Morikawa2), Mariko Kawaguchi1), Toshikazu Kondo1)
1)

1)

2)

1)

1)

3)

1)
Department of Forensic Medicine, Wakayama Medical University, Wakayama, Japan, 2)Department of Anatomy and Neurobiology, Wakayama
Medical University, Wakayama, Japan, 3)Laboratory of Cell Growth and Differentiation, Institute for Quantitative Biosciences, The University ofTokyo, Tokyo, Japan

WS17-16-P

Physiological function of chemokine CCL20 and its receptor CCR6 in multiple sclerosis in mice
〇 Nozomi Sachi, Naganori Kamiyama, Sotaro Ozaka, Shimpei Ariki, Thanyakorn Chalalai, Yomei Kagoshima,
Takashi Kobayashi
Department of Infectious Disease Control, Faculty of Medicine, Oita University, Oita, Japan.

December 8
WS18

T cell function and diseases-2 (Disease models)

WS18-01-O/P

RIPK1 blocks T cell senescence mediated by RIPK3 and caspase-8〇 Takayuki Imanishi, Takashi Saito
Laboratory for Cell Signaling, RIKEN Center for Integrative Medical Sciences (IMS), Yokohama, Japan124

WS18-02-O/P

Role of Bcl6 in DNA methylation-mediated T cell senescence and tumorigenesis〇 Hiroko Nakatsukasa , Akihiko Yoshimura
1)

2)

1)

Laboratory of Microbiology and Immunology, Graduate School of Pharmaceutical Sciences, Chiba University, Chiba, Japan, 2)Department ofMicrobiology and Immunology, Keio University School of Medicine, Tokyo, Japan

WS18-03-O/P

Human GC-Tfh cells differentiate into IL-10+ follicular T cells with regulatory functions
1, 2)
2)
1, 2)
1, 2)
2)
1, 2)
〇 Shusei Fujioka , Yusuke Imoto , Mayu Fujioka , Hiroyuki Yoshitomi , Yasuaki Hiraoka , Hideki Ueno

1)
Department of Immunology, Graduate School of Medicine, Kyoto University, Kyoto, Japan, 2)Institute for the Advanced Study of Human Biology(ASHBi), Kyoto, Japan

WS18-04-O/P

	Phenotypic and functional analyses reveal self-driven memory-phenotype CD4+ T lymphocytes as aheterogeneous population distinct from foreign antigen-specific memory cells
1, 2, 3), Thomas Ciucci4, 5), Kwang Soon Kim6), Shunichi Tayama1), Akihisa Kawajiri1), Naoto Ishii1),〇 Takeshi Kawabe
2)
Dragana Jankovic , Jinfang Zhu3), Jonathan Sprent7, 8), Remy Bosselut4), Alan Sher2)
1)

Department of Microbiology and Immunology, Tohoku University Graduate School of Medicine, Sendai, Japan., 2)Immunobiology Section,
Laboratory of Parasitic Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, USA.,
3)
Molecular and Cellular Immunoregulation Section, Laboratory of Immune System Biology, National Institute of Allergy and Infectious Diseases,
National Institutes of Health, Bethesda, MD, USA., 4)Laboratory of Immune Cell Biology, Center for Cancer Research, National Cancer Institute,
National Institutes of Health, Bethesda, MD, USA., 5)David H. Smith Center for Vaccine Biology and Immunology, Department of Microbiology
and Immunology, University of Rochester, Rochester, NY, USA., 6)Department of Integrative Biosciences and Biotechnology, Pohang University of
Science and Technology, Pohang, Republic of Korea., 7)Immunology Division, Garvan Institute of Medical Research, Darlinghurst, NSW, Australia,
8)
St. Vincent's Clinical School, University of New South Wales, Sydney, NSW, Australia
WS18-05-O/P

Nuclear receptor RORα regulates bystander activation of memory T cells〇 Kensuke Takada, Zimeng Cai, Hironobu Mita, Mina Kozai, Shangyi Wang, Mutsumi Inaba
Laboratory of Molecular Medicine, Faculty of Veterinary Medicine, Hokkaido University

WS18-06-O/P

Charcterization of self glycolipids presented by CD1d that activate NKT cells
1, 2, 3)
, Noriyuki Tomiyasu4), Yoshihiro Izumi4), Akihiro Imamura5), Eri Ishikawa1, 2), Atsushi Kumanogoh3, 6),〇 Yuki Hosono
5)
Hideharu Ishida , Takeshi Bamba4), Sho Yamasaki1, 2, 6)
1)
Laboratory of Molecular Immunology, Immunology Frontier Research Center, Osaka University, Suita, Japan, 2)Department of Molecular
Immunology, Research Institute for Microbial Diseases, Osaka University, Suita, Japan, 3)Department of Respiratory Medicine and Clinical
Immunology, Graduate School of Medicine, Osaka University, Suita, Japan, 4)Division of Metabolomics, Medical Institute of Bioregulation,
Kyushu University, Fukuoka, Japan, 5)Department of Applied Bioorganic Chemistry, Gifu University, Gifu, Japan, 6)Center for Infectious Disease
Education and Research, Osaka University, Suita, Japan

WS18-07-O/P

A novel subset of Treg controls the progression of colorectal cancer in humans and mice
〇 Kazushige Obata-Ninomiya, Steven F. Ziegler
Benaroya Research Institute, WA, US

WS18-08-O/P

	Critical roles of an endoribonuclease N4bp1 in regulating CD8 T cell homeostasis and cancer
immunosurveillance〇 Guohao Liu, Yee Kien Chong, Osamu Takeuchi
Department of Medical Chemistry Graduate School of Medicine, Kyoto University

WS18-09-P

Nr4a promotes T cell mediated immunosenescence〇 Daisuke Aki, Akihiko Yoshimura
Department of Microbiology and Immunology, Keio University School of Medicine, Tokyo, Japan

WS18-10-P

Aging process augments Th17-type airway inflammation by IL-18〇 Masakiyo Nakahira, Etsushi Kuroda
Department of Immunology, Hyogo Medical University

WS18-11-P

Bob1 regulates memory T follicular helper cells to control antigen-specific humoral immunity
1, 2)
1)
1)
1)
1)
1)
〇 Masahiro Yanagi , Ippei Ikegami , Shiori Kamiya , Taiki Sato , Hiroshi Sakamoto , Mihoko Ohashi ,1)2)1)
Ryuta Kamekura , Hirofumi Chiba , Shingo Ichimiya
1)

Department of Human Immunology, Research Institute for Frontier Medicine, Sapporo Medical University School of Medicine, Sapporo, Japan,
Department of Respiratory Medicine and Allergology, Sapporo Medical University School of Medicine, Sapporo, Japan

2)

125

WS18-12-P

A role of Achaete-scute complex homolog 2 in T follicular regulatory cell development
1, 2)
2)
2)
2)
2)
2)
〇 Kazuma Iida , Kotaro Suzuki , Takahiro Kageyama , Kazuyuki Meguro , Shigeru Tanaka , Arifumi Iwata ,2)2)
Akira Suto , Hiroshi Nakajima
1)

Leading Graduate School Program, 2)Department of Allergy and Clinical Immunology, Graduate School of Medicine Chiba University, Chiba, Japan

WS18-13-P

Arf pathway plays a critical role in metabolic reprogramming during T cell activation
1)
1, 2)
1)
3, 4)
5)
〇 Mami Sumiyoshi , Yui Kotani , Satoshi Matsuda , Yoichi Maekawa , Chikako Shimokawa
1)

Department of Cell Signaling, Institute of Biomedical Science, Kansai Medical University, Osaka, Japan, 2)Department of Biological Science,
Graduate School of Human and Science, Nara Women's University, Nara, Japan, 3)Department of Parasitology and Infectious Diseases, Gifu
University Graduate School of Medicine, Gifu, Japan, 4)Domain of Integrated Life Systems, Centre for Highly Advanced Integration of Nano andLife Sciences (G-CHAIN), Gifu University, Gifu, Japan, 5)Department of Parasitology, National Institute of Infectious Disease, Tokyo, Japan
WS18-14-P

	Rapid accumulation of circulating memory-phenotype CD4+ T lymphocytes in the gut critically contributes
to tissue injury driven by intestinal ischemia and reperfusion
1, 2)
1)
1)
1)
1)
1)
2)
〇 Kosuke Sato , Jing Li , Ziying Yang , Akihisa Kawajiri , Shunichi Tayama , Yuko Okuyama , Motoshi Wada ,Naoto Ishii1), Takeshi Kawabe1)
1)Department of Microbiology and Immunology, Tohoku University Graduate School of Medicine, Sendai, Japan., 2)Department of PediatricSurgery, Tohoku University Graduate School of Medicine, Sendai, Japan
WS18-15-P

	Aryl hydrocarbon receptor signals in epithelial cells govern the recruitment and location of Helios+ Tregs
in the gut〇 Yusuke Yoshimatsu , Kentaro Miyamoto , Tomohisa Sujino , Yohei Mikami , Nobuhiro Nakamoto ,Takanori Kanai1)
1)

2)

1)

1)

1)

1)

Division of Gastroenterology and Hepatology, Department of Internal Medicine, Keio University School of Medicine, Tokyo, Japan, 2)Miyarisan
Pharmaceutical Co., Research Laboratory, Tokyo, Japan

WS18-16-P

Fluctuations in SOCS1 expression in the pathogenesis of SLE〇 Reiko Takahashi, Yoshitaka Imura
Department of Clinical Immunology and Rheumatology, Tazuke Kofukai Medical Research Institute, Kitano Hospital, Osaka, Japan

WS18-17-P

Abcd1-deficiency supports Th1-lineage commitment〇 Reina Maeda, Mitsuki Azuma, Masashi Morita, Takanori So
Laboratory of Molecular Cell Biology, Graduate School of Medicine and Pharmaceutical Sciences, University of Toyama, Toyama, Japan

WS18-18-P

	Agonistic anti-PD-1 antibodies stimulating immunosuppressive activity of PD-1 alleviate inflammatory
diseases
1)
1, 2)
1, 3)
1, 2)
1, 2)
4)
〇 Akio Ohta , Kensuke Suzuki , Masaki Tajima , Yosuke Tokumaru , Yuya Oshiro , Satoshi Nagata ,
4)
5)
5)
3)
Haruhiko Kamada , Miho Kihara , Kohei Nakano , Tasuku Honjo
1)

Department of Immunology, Foundation for Biomedical Research and Innovation at Kobe, 2)Pharmaceutical R&D Division, Meiji Seika Pharma
Co. Ltd., 3)Center for Cancer Immunotherapy and Immunobiology, Graduate School of Medicine, Kyoto University, 4)Center for Drug Design
Research, National Institutes of Biomedical Innovation, Health and Nutrition, 5)Laboratory for Animal Resources and Genetic Engineering, RIKEN
Center for Biosystems Dynamics Research
WS18-19-P

A PKD inhibitor cancels the effect of PD-1 blockade in a murine model of cancer immunotherapy〇 Shunsuke Chikuma
Microbiology and Immunology, Keio University School of Medicine, Tokyo, Japan

WS18-20-P	Immunological Functions of Memory-Phenotype CD4+ T lymphocytes in Anti-Tumor Responses and Graftversus-Host Disease〇 Ziying Yang, Hideaki Watanabe, Jing Li, Akihisa Kawajiri, Kosuke Sato, Shunichi Tayama, Yuko Okuyama,
Naoto Ishii, Takeshi Kawabe
Department of Microbiology and Immunology, Tohoku University Graduate School of Medicine, Sendai, Japan

WS18-21-P	Inhibition of ACC1-dependent de novo fatty acid biosynthesis augments Th9 cell differentiation and antitumor activity〇 Takahiro Nakajima, Toshio Kanno, Yusuke Endo
Department of Frontier Research and Development, Laboratory of Medical Omics Research, Kazusa DNA Research Institute, Chiba, Japan

126

The molecular mechanism of T cell dysfunction by NR4A transcription factors and its rejuvenation

WS18-22-P〇 Tanakorn Srirat, Akihiko Yoshimura
Keio University
WS18-23-P

	Nutrient condition in the microenvironment determines essential metabolisms of CD8 T cells forenhanced IFNγ production by metformin〇 Ruoyu Chao, Mikako Nishida, Nahoko Yamashita, Miho Tokumasu, Weiyang Zhao, Ikuru Kudo, Heiichiro Udono
Department of Immunology, Okayama University Graduate School of Medicine, Dentistry, and Pharmaceutical Sciences Japan

Dependence of tumor-reactive T cells on antigen presentation pathway

WS18-24-P

1)
1, 2)
1)
1)
1)
〇 Haruka Shimizu , Hiroyasu Aoki , Mikiya Tsunoda , Kouji Matsushima , Satoshi Ueha
1)

Division of Molecular Regulation of Inflammatory and Immune Diseases, Research Institute for Biomedical Sciences, Tokyo University of
Science, Tokyo, Japan, 2)Department of Hygiene, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan
WS18-25-P

	PD-1highCXCR5–CD4+ Peripheral Helper T (Tph) cells Promote CXCR3+ Plasmablasts in the early phaseof COVID-19
1, 2, 3), Subhasis Mohanty4), Kenneth Hoehn5), Patrick Wong2), Steven Kleinstein2, 5, 6),〇 Hiromitsu Asashima
2, 4, 7)
Akiko Iwasaki, Albert Shaw4), David Hafler1, 2), Tomokazu Sumida1, 2), Isao Matsumoto3)
1)

Department of Neurology, Yale School of Medicine, New Haven, CT, USA, 2)Department of Immunobiology, Yale School of Medicine, New
Haven, CT, USA, 3)Department of Rheumatology, Faculty of Medicine, University of Tsukuba, Tsukuba city, Ibaraki, Japan., 4)Section of Infectious
Diseases, Department of Internal Medicine, Yale School of Medicine, Yale University, New Haven, CT, USA, 5)Department of Pathology, Yale
School of Medicine, New Haven, CT, USA, 6)Interdepartmental Program in Computational Biology and Bioinformatics, Yale University, New
Haven, CT, USA, 7)Howard Hughes Medical Institute, Chevy Chase, MD, USA

December 8
WS19

Mucosal and Skin Surface Barrier

WS19-01-O/P

Roles of Disialylated Glycan in the Gut Mucosal Barrier
1, 2)
1, 3)
1, 3)
〇 Mugen Taniguchi , Ryu Okumura , Kiyoshi Takeda

1)

Laboratory of Immune Regulation, Department of Microbiology and Immunology, Graduate School of Medicine, Osaka University, Suita,
Japan., 2)Infectious Diseases Unit, Department of Medical Innovations, New Drug Research Division, Otsuka Pharmaceutical Co., Ltd.,
Tokushima, Japan., 3)WPI Immunology Frontier Research Center, Osaka University, Suita, Japan
WS19-02-O/P

The protective function of conjunctival goblet cell mucin sialylation
1)
1, 2, 3)
, Saaya Fukase1, 2, 3), Meiko Kimura1, 2, 3), Yasuharu Kume1, 2, 3), Kumi Izawa1),〇 Tomoaki Ando , Moe Matsuzawa
1)
1)
Ayako Kaitani , Ko Okumura , Akira Matsuda3), Akira Murakami3), Nobuyuki Ebihara2, 3), Jiro Kitaura1, 4)
1)
Atopy (Allergy) Research Center, Juntendo University Graduate School of Medicine (Tokyo, Japan), 2)Department of Ophthalmology, Juntendo
University Urayasu Hospital (Chiba, Japan), 3)Department of Ophthalmology, Juntendo University Graduate School of Medicine, 4)Department of
Science of Allergy and Inflammation, Juntendo University Graduate School of Medicine (Tokyo, Japan)

WS19-03-O/P

Tuft cell-derived IL-25 induced by cecectomy ameliorates colitis development〇 Shunya Hatai , Yasutaka Motomura
1)

1, 2, 3)

, Koji Hosomi4), Jun Kunisawa4), Kazuyo Moro1, 2, 3, 5)

1)

Laboratory for Innate Immune Systems, Department of Immunology and Microbiology, Osaka University Graduate School of Medicine,
Laboratory for Innate Immune Systems, RIKEN Center for Integrative Medical Sciences (IMS), 3)Laboratory for Innate Immune Systems, Osaka
University Immunology Frontier Research Center, 4)Laboratory of Vaccine Materials, Center for Vaccine and Adjuvant Research, and Laboratoryof Gut Environmental System, National Institutes of Biomedical Innovation, Health, and Nutrition (NIBIOHN), 5)Laboratory for Innate Immune
Systems, Department of Microbiology and Immunology, Osaka University Graduate School of Frontier Biosciences2)

WS19-04-P

	IkappaBzeta regulates IL-17-triggered gene program in intestinal epithelial cells that restricts colonizationof SFB and prevents autoimmune disorders〇 Soh Yamazaki , Naohiro Inohara , Yousuke Tsuneoka , Hideo Yagita , Takaharu Katagiri , Takashi Nishina ,Tetuo Mikami5), Hiroyasu Nakano1)
1)

2)

3)

1)

4)

1)

1)

Department of Biochemistry, Toho University School of Medicine, 2)Department of Pathology, University of Michigan Medical School,
Department of Anatomy, Toho University School of Medicine, 4)Department of Immunology, Juntendo University Graduate School of Medicine,5)
Department of Pathology, Toho University School of Medicine
3)127

WS19-05-P

	Visible pathogenetic analysis of ulcerative colitis-like inflammatory bowel disease using ER-stress
reporter gene and HLA-DR4 transgenic mice
〇 Ryo Ikeda , Atsushi Irie , Yoshihiro Komohara , Hiroyuki Oshiumi
1)

1)

2)

1)

1)

2)

Dep Immunol, Grad Sch Med Sci, Kumamoto university,, Dep Cell Pathol, Grad Sch Med Sci, Kumamoto university

WS19-06-P

Changes in intestinal GABA concentration by intervention in gut microbiota and its physiological effects〇 Mion Ikegami , Gaku Harata , Kenji Miyazawa , Yushiro Fuji , Hiroshi Matsufuji , Yusuke Nakanishi ,Kyoko Takashi1)
1)

2)

2)

1)

1)

1)

1)

Graduate School of Bioresource Sciences, Nihon University, Kanagawa, Japan, 2)Technical Research Laboratory, Takanashi Milk Products Co.,
Ltd, Kanagawa, Japan

WS19-07-P

	Antibiotics promote epithelial cell death and eosinophilic infiltration in the gut caused by an aluminumcontaining food additive〇 Ayako Wakabayashi , Atsuko Owaki , Ken Iwatsuki , Yasuhiro Nishiyama , Shoji Matsune , Rimpei Morita
1)

1)

2)

3)

1)

4)

1)

2)

Department of Microbiology and Immunology, Nippon Medical School, Tokyo, Japan, Department of Nutritional Science and Food Safety,
Faculty of Applied Bioscience, Tokyo University of Agriculture, Tokyo, Japan, 3)Department of Neurological Science, Nippon Medical School,
Tokyo, Japan, 4)Department of Otolaryngology, Nippon Medical School Musashi Kosugi Hospital, Kanagawa, Japan
WS19-08-P

	Augmented leptin-induced trefoil factor 3 expression and epidermal growth factor receptor transactivationdifferentially influences neoplasia progression in the stomach and colorectum of dietary fat-induced
obese mice
〇 Kyoko Inagaki-Ohara
Division of Host Defense, Department of Life Sciences, Faculty of Life and Environmental Sciences, Prefectural University of Hiroshima

WS19-09-P	Irisin promotes intestinal epithelial cell proliferation via Wnt/beta-catenin and integrin beta 1/FAK
signaling pathway〇 Gaowa Arong, Eun Jeong Park, Motomu Shimaoka
Mie University

WS19-10-P	Local MMP9-plasminogen axis is involved in the development of inflammation in intestine of dogs andpatients
1, 2)
3)
1)
2, 4)
1, 5)
3)
〇 Takeshi Yamasaki , Noriyuki Nagata , Toru Atsumi , Rie Hasebe , Yuki Tanaka , Yong Bin Teoh ,
6)
7)
1)
1)
3)
Hiroshi Ohta , Yoshihiro Matsuno , Shimpei Kubota , Shintaro Hojyo , Mitsuyoshi Takiguchi , Masaaki Murakami1, 2, 5)
1)Division of Molecular Psychoimmunology, Institute for Genetic Medicine, Graduate School of Medicine, Hokkaido University, Sapporo,
Japan, 2)Division of Molecular Neuroimmunology, National Institute for Physiological Sciences, National Institute of Natural Sciences, Okazaki,
Japan, 3)Laboratory of Veterinary Internal Medicine, Department of Clinical Sciences, Graduate School of Veterinary Medicine, Hokkaido
University, Sapporo, Japan, 4)Center for infectious Cancers, Institute for Genetic Medicine, Graduate School of Medicine, Hokkaido University,
Sapporo, Japan, 5)Group of Quantum Immunology, Institute for Quantum Life Science, National Institute for Quantum and Radiological Scienceand Technology (QST), Inage, Japan, 6)Laboratory of Veterinary Internal Medicine, Department of Small Animal Clinical Sciences, School of
Veterinary Medicine, Rakuno Gakuen University, Ebetsu, Hokkaido, Japan, 7)Department of Surgical Pathology, Hokkaido University Hospital,
Sapporo, Japan

WS19-11-P

	
High-efficient genetic engineering of enteroids using mouse isolated crypts revealing the intestinal function
1)
1, 2)
1)
2)
1, 2)
1, 2)
〇 Shuya Ohira , Yuki Yokoi , Yuito Kaibori , Yu Shimizu , Tokiyoshi Ayabe , Kiminori Nakamura
1)

Graduate School of Life Science, Hokkaido University, Sapporo, Japan, 2)Department of Cell Biological Science, Faculty of Advanced Life
Science, Hokkaido University, Sapporo, Japan

WS19-12-O/P

Intracellular metabolic adaptation of intraepithelial CD4+CD8aa+ T lymphocytes〇 Yosuke Harada , Tomohisa Sujino , Kentaro Miyamoto , Ena Nomura , Takanori Kanai
1)

2)

3)

1)

1)

1)

2)

Department of Gastroenterology and Hepatology, School of Medicine, Keio University, Tokyo, Japan, Center for Diagnostic and Therapeutic
Endoscopy, Keio University Hospital, Tokyo, Japan, 3)Miyarisan Pharm. Co. Ltd. Tokyo, Japan
WS19-13-O/P

Epithelial HVEM maintains intraepithelial T cell survival and contributes to host protection
1, 2)
1)
1)
1)
1)
〇 Daisuke Takahashi , Goo-Young Seo , Qingyang Wang , Zbigniew Mikulski , Mitchell Kronenberg

1)

La Jolla Institute for Immunology, 2)Keio University Faculty of Phamacy

128

WS19-14-O/P	Basolateral sorting of CD166 in intestinal epithelial cells by clathrin adaptor protein AP-1B is required forinteraction with intraepithelial lymphocytes〇 Ryohtaroh Matsumoto , Kosuke Ogata , Daisuke Takahashi , Yusuke Kinashi , Takahiro Yamada , Aiko Saeki ,Hiroshi Ohno3), Yasushi Ishihama2), Shunsuke Kimura1), Koji Hase1)
1)

2)

1)

1)

1)

1)

1)
Division of Biochemistry, Graduate School of Pharmaceutical Science, Keio University, 2)Department of Molecular & Cellular BioAnalysis,
Graduate School of Pharmaceutical Sciences, Kyoto University, 3)Laboratory of Intestinal Ecosystem, RIKEN Center for Integrative Medical
ScienceWS19-15-P
WS19-16-P

Withdrawn	Notch signal controls final differentiation of TCRγδ+CD8αα+ intraepithelial lymphocytes in the small
intestine〇 Chieko Ishifune, Koji Yasutomo
Department of Immunology and Parasitology, Tokushima University Graduate School of Biomedical Sciences, Tokushima, Japan

WS19-17-P

Characterization of CD8 positive γδT cells in psoratic skin inflammation〇 Himawari Matsunaga, Koichi Sudo, Kazuhiko Takahara

Laboratory of Immunobiology, Graduate School of Biostudies, Kyoto University, Kyoto, Japan
WS19-18-O/P	
Intestinal barrier dysfunction by intestine-specific AP-1B deficiency causes IgA nephropathy-like symptoms〇 Yusuke Kinashi , Daisuke Takahashi , Hiroshi Ohno , Shunsuke Kimura , Koji Hase
1)

1)

2)

1)

1)

1)

2)

Division of Biochemistry, Graduate School of Pharmaceutical Science, Keio University, Tokyo, Japan, Laboratory for Intestinal Ecosystem,
RIKEN Center for Integrative Medical Sciences, Yokohama, Japan
WS19-19-O/P

Selective IgA deficiency induces spontaneous inflammation in the ileum〇 Takashi Nagaishi , Daiki Yamada , Tadahiko Inoue , Richard S. Blumberg , Ryuichi Okamoto , Takahiro Adachi
1)

1)

1)

2)

1)

1)

3)

2)

Department of Gastroenterology, Graduate School of Medical Science, Tokyo Medical and Dental University, Tokyo, Japan., Gastroenterology
Division, Brigham and Women’s Hospital, Harvard Medical School, Boston, MA, USA., 3)Department of Precision Health, Medical ResearchInstitute, Tokyo Medical and Dental University, Tokyo, Japan
WS19-20-O/P

Detection of S-IgA antibodies in plasma of neonates and identification of the source〇 Kaori Ito, Kohta Saukurai, Mutsumi Furukawa, Tomonori Nochi
International Education and Research Center for Food and Agricultural Immunology, Graduate School of Agricultural Science, Tohoku University,
Miyagi, Japan

WS19-21-P

IL-21 and IL-5 coordinately induce surface IgA+ cells
1, 2)
2)
1)
〇 Masaaki Hashiguchi , Hidefumi Kojima , Yoshiko Iwai

1)
Department of Cell Biology, Institute of Advanced Medical Sciences, Nippon Medical School, 2)Divison of Host Defense, Research Center for
Advanced Medical Science, Dokkyo Medical University School of Medicine

WS19-22-P

Does BNT162b2 inoculation enhance in the oral mucosal immunity?
〇 Tomoko Shimizu, Keiichi Tsukinoki
Kanagawa Dental University, Yokosuka, Kanagawa, Japan

WS19-23-P

	Different ability between Peyer’s patches and Cecal patches to generate IgA+/ IgG2b+ B cells that arereactive to commensal microbiota
1)
1)
2)
3)
1, 4)
1)
〇 Hiraku Okada , Masato Tsuda , Satoshi Hachimura , Yoshimasa Takahashi , Kyoko Takahashi , Akira Hosono
1)

Department of Food Bioscience and Biotechnology, College of Bioresource Sciences, Nihon University, Fujisawa-shi, Kanagawa, Japan,
Research Center for Food Safety, Graduate School of Agricultural and Life Sciences, The University of Tokyo, Tokyo, Japan., 3)Research Center
for Drug and Vaccine Development, National Institute of Infectious Diseases, Tokyo, Japan., 4)Department of Applied Biological Science, College
of Bioresource Sciences, Nihon University, Fujisawa-shi, Kanagawa, Japan
2)

129

December 8
WS20

Dendritic cells and macrophages-2: Myeloid cell linage and their differentiation

WS20-01-P

	Unique cell harvesting technology without trypsinization - Recovery of various cell types by temperatureresponse cultureware UpCell® 〇 Asumi Yoshihara, Eriko Ikeda, Yuzo Kasuya
Cultureware Development Department, CellSeed inc., Tokyo, Japan

WS20-02-O/P	Transcriptomic and functional analyses uncover an immature subpopulation of basophils in the bonemarrow and FoxO1 as a transcription factor involved in the regulation of basophil responsiveness〇 Junya Ito , Kensuke Miyake , Kazufusa Takahashi , Shigeyuki Shichino , Hajime Karasuyama
1)

1)

1)

2)

1)

1)

Inflammation, Infection and Immunity Laboratory, Advanced Research Institute, Tokyo Medical and Dental University, Tokyo, Japan, 2)Division of
Molecular Regulation of Inflammatory and Immune Diseases, Research Institute of Biomedical Sciences, Tokyo University of Science, Noda, Japan

WS20-03-P

	Properties and functional analysis of cultured common lymphoid progenitor-derived monocytic cells(cCLP-M)〇 Yohei Kawano, Mizuki Moriyama, Shun Ohki, Yasuo Kitajima, Tomoharu Yasuda
Dept. of Immun., Hiroshima University, Hiroshima, Japan

WS20-04-O/P

Activation of retinoid X receptor promotes differentiation of monocytes into CX3CR1hi macrophages in the colon〇 Wakana Ohashi , Masayoshi Onuki , Eiji Umemoto , Masaru Ishii , Kiyoshi Takeda , Hiroki Kakuta , Koji Hase
1)

1)

2)

1)

3)

4)

5)

1)

2)

Division of Biochemistry, Faculty of Pharmacy, Keio University, Tokyo, Japan, Laboratory of Microbiology and Immunology, School of
Pharmaceutical Sciences, University of Shizuoka, Shizuoka, Japan, 3)Department of Immunology and Cell Biology, Graduate School of Medicine,
Osaka University, Osaka, Japan, 4)Department of Microbiology and Immunology, Graduate School of Medicine, Osaka University, Osaka, Japan,
5)
Division of Pharmaceutical Sciences, Graduate School of Medicine Dentistry and Pharmaceutical Sciences, Okayama University, Okayama Japan
WS20-05-O/P

Identification of differentiation pathway for neutrophil-like monocytes during emergency hematopoiesis
1)
1)
2)
3, 4)
5)
5)
〇 Naoki Ikeda , Ayaka Iwata , Takashi Kamatani , Tatsuhiko Tsunoda , Yoshihiro Hayashi , Hironori Harada ,Yuka Harada6), Masato Tanaka1), Kenichi Asano1)
1)

Lab. of Immune Regulation, Tokyo University of Pharmacy and Life Sciences, 2)M&D Data Science Center, Tokyo Medical and Dental University,
Graduate School of Science, The University of Tokyo, 4)RIKEN Center for Integrative Medical Sciences, 5)Lab. of Oncology, Tokyo University of
Pharmacy and Life Sciences, 6)Department of Clinical Laboratory, Komagome Hospital3)

WS20-06-P

Role of innate myeloid cells in functional recovery after ischemic stroke〇 Jun Tsuyama, Takashi Shichita
Tokyo Metropolitan Institute of Medical Science, Tokyo, Japan

WS20-07-P

	The role of an intracellular chaperones of long-chain fatty acids FABP7 in liver macrophages during liverdiseases〇 Hirofumi Miyazaki, Shuhan Yang, Yuji Owada
Department of Organ Anatomy, Graduate school of medicine, Tohoku university

WS20-08-P

Altered immune cell composition in human Primary biliary cholangitis liver〇 Shuhe Ma, Hideki Ueno
Immunology Group, Institute for the Advanced Study of Human Biology (ASHBi) KUIAS Kyoto University, Kyoto, Japan

WS20-09-O/P

CSF1-producing cells in the intestine contributes to the maintenance of macrophages〇 Daichi Nonaka, Eriko Sumiya, Shinichiro Sawa
Medical institute of bioregulation Kyushu university

WS20-10-O/P

	
Molecular mechanisms of short-chain fatty acids-mediated transactivation of integrin genes in dendritic cells〇 Weiting Zhao, Kazuki Nagata, Naoto Ito, Masakazu Hachisu, Chiharu Nishiyama
Department of Biological Science and Technology, Tokyo University of Science, Tokyo, Japan

130

WS20-11-P

	The deficiency of a nuclear receptor NR4A3 deteriorate psoriasis by enhancing TLR7-mediated activationof dendritic cells〇 Mayuka Katagiri , Naoto Ito , Natsuki Minamikawa , Takuya Yashiro , Nobuhiro Nakano , Kazuki Nagata ,Akihiko Yoshimura3), Chiharu Nishiyama1)
1)

1)

1)

1)

2)

1)

1)
Department of Biological Science and Technology, Tokyo University of Science, Tokyo, Japan, 2)Atopy (Allergy) Research Center, Juntendo
University Graduate School of Medicine, Tokyo, Japan, 3)Department of Microbiology and Immunology, Keio University School of Medicine,Tokyo, Japan

WS20-12-P	The roles of transcription factors PU.1, IRF4, and IRF8 in regulation of the genes expressed in dendritic cells〇 Naoto Ito , Mayumi Hirakawa , Natsuki Minamikawa , Mayuka Katagiri , Kazuki Nagata , Tomokatsu Ikawa ,Chiharu Nishiyama1)
1)

2)

1)

1)

1)

2)

1)

Department of Biological Science and Technology, Faculty of Advanced Engineering, Tokyo University of Science, Tokyo, Japan, 2)ResearchInstitute for Biomedical Sciences, Tokyo University of Science, Chiba, Japan

WS20-13-P

SIRPα and CD47 promote cDC2 survival through the regulation of transcriptional factor Nr4a3
1, 2)
2)
2)
2)
2)
1, 2)
〇 Satomi Komori , Yasuyuki Saito , Taichi Nishimura , Hiroki Yoshida , Risa Sugihara , Tomoko Takai ,
2)
2)
1, 2)
Takenori Kotani , Yoji Murata , Takashi Matozaki
1)

Division of Biosignal Regulation, Department of Biochemistry and Molecular Biology, Kobe University Graduate School of Medicine, Kobe,
Japan, 2)Division of Molecular and Cellular Signaling, Department of Biochemistry and Molecular Biology, Kobe University Graduate School of
Medicine, Kobe, Japan
WS20-14-P

	An optimized small molecule inhibitor cocktail supports maturation of dendritic cells in human monocyte
derived dendritic cell culture system
1)
1, 2)〇 Shintaro Matsuba , Nobuyuki Onai
1)

Department of Immunology, Kanazawa Medical University, Uchinada, Japan, 2)Research support center, Medical Research Institute, Kanazawa
Medical University, Uchinada, Japan

WS20-15-O/P

Migratory CD301b+ cDC2 cells instruct the fate of effector CD4 T cells through cognate interactions〇 Naoya Tatsumi, Yosuke Kumamoto
Rutgers New Jersey Medical School, Newark, NJ, USA

WS20-16-P

Advanced classification of liver resident and bone marrow-derived macrophages〇 Hiroyuki Nakashima , Azusa Kato , Hiromi Miyazaki , Seigo Ito , Masahiro Nakashima , Manabu Kinoshita
1)

1)

2)

3)

1)

1)

1)

2)

Department of Immunology and Microbiology, National Defense Medical College, Division of Biomedical Engineering, National Defense
Medical College Research Institute, 3)Department of Internal Medicine, Self-Defense Force Iruma Hospital
WS20-17-P

Constitutive loss of conventional dendritic cells promotes tumor development〇 Moe Tominaga, Tomofumi Uto, Tomohiro Fukaya, Katsuaki Sato
Division of Immunology, Department of Infectious Diseases, Faculty of Medicine, University of Miyazaki

WS20-18-P

The novel CD103- dendritic cell-like subset found in rat thymus〇 Yasushi Sawanobori, Hisashi Ueta, Yusuke Kitazawa, Nobuko Tokuda
Department of Anatomy, Dokkyo Medical University, Mibu, Tochigi, Japan

WS20-19-O/P	The aryl hydrocarbon receptor instructs the immunomodulatory profile of a subset of Clec4a4+ eosinophils
unique to the small intestine
1, 2)
2)
2)
2)
2)
〇 Jun Kasamatsu , Wei-Le Wang , Susan Gilfillan , Marina Cella , Marco Colonna

1)
Department of Intelligent Network for Infection Control Tohoku University Graduate School of Medicine, 2)Department of Pathology and
Immunology, Washington University School of Medicine in Saint Louis

WS20-20-O/P

	
Identification of a novel macrophage subset involved in pulmonary fibrosis by intravital imaging techniques〇 Akio Suzuki, Junichi Kikuta, Masaru Ishii
Department of Immunology and Cell Biology, Graduate School of Medicine and Frontier Biosciences, Osaka University, Osaka, Japan

WS20-21-P

	Single-cell RNA sequencing analysis for the differentiation pathway of arthritis-associatedosteoclastogenic macrophages〇 Tomoya Agemura, Junichi Kikuta, Masaru Ishii
Department of Immunology and Cell Biology, Graduate School of Medicine and Frontier Biosciences, Osaka University

131December 8
WS21

Molecular and cellular diversity of allergic diseases (II)WS21-01-O/P

Tigit mediates activation-induced cell death of ILC2s
1, 2)
1)
1)
1)
3)
〇 Toshiki Yamada , Akane Fuchimukai , Megumi Tatematsu , Shunsuke Takasuga , Hideyuki Yoshida ,
4)
4, 5)
1)
Kazuko Shibuya , Akira Shibuya , Takashi Ebihara
1)
Department of Medical Biology, Akita University Graduate School of Medicine, 2)Department of Otorhinolaryngology-Head and Neck Surgery,
Akita University Graduate School of Medicine, 3)YCI Laboratory for Immunological Transcriptomics, RIKEN Center for Integrative Medical
Sciences, 4)Department of Immunology, Faculty of Medicine, University of Tsukuba, 5)Life Science Center for Survival Dynamics, Tsukuba
Advanced Research Alliance (TARA), University of Tsukuba

WS21-02-O/P

Lung local IL-7 affect the maintenance, distribution, and activation of ILC2 in allergic airway inflammations〇 Daichi Takami, Shinya Abe, Akihiro Shimba, Koichi Ikuta
Institute for Life and Medical Sciences, Kyoto University, Kyoto, Japan

WS21-03-O/P

The role of local Th2 activation in the development of allergic rhinitis〇 Saya Tezuka, Kazufumi Matsushita, Etsushi Kuroda
Department of Immunology, Hyogo Medical University, Hyogo, Japan

WS21-04-O/P

The role of IL-13 on dendritic cells is critical for type 2 immune responses〇 Yasuyo Harada, Masato Kubo
Research Institute for Biomedical Sciences, Tokyo University of Science, Chiba, Japan

WS21-05-O/P	The anti-allergic effects of short chain fatty acids and niacin targeting IgE-dependent mast cell activation
via modulating GPCR-signaling of EP3 and GPR109A, and by epigenetic regulation
1)
1)
1)
1)
1)
2, 3)
1)
〇 Daisuke Ando , Kazuki Nagata , Tsubasa Ashikari , Kandai Ito , Naoto Ito , Makoto Arita , Chiharu Nishiyama

1)
Department of Biological Science and Technology, Tokyo University of Science, Tokyo, Japan, 2)Graduate School of Pharmaceutical Sciences,
Keio University, Tokyo, Japan, 3)RIKEN Center for Integrative Medical Science, Kanagawa, Japan

WS21-06-O/P

	Development of a murine model for oral allergy syndrome to identify IgE cross-reactive pollen and foodallergens
1, 2)
1, 3)
1)
1)
1)
1)
〇 Risa Yamamoto , Anna Kamei , Kumi Izawa , Tomoaki Ando , Ayako Kaitani , Akie Maehara ,Yasuharu Kume1, 4), Hexing Wang1, 3), Koji Tokushige1, 3), Nobuhiro Nakano1), Ko Okumura1), Jiro Kitaura1)
1)

Atopy (Allergy) Research Center, Juntendo University Graduate School of Medicine, Tokyo, Japan, 2)Juntendo University School of Medicine (5thyear medical student), Tokyo, Japan, 3)Department of Science of Allergy and Inflammation, Juntendo University Graduate School of Medicine,Tokyo, Japan, 4)Department of Ophthalmology, Juntendo University Urayasu Hospital, Chiba, Japan
WS21-07-O/P

The kappa opioid alleviates the OVA-induced food allergy via the brain-gut axis and immunomodulation〇 Kazuki Nagata , Hiroshi Nagase , Chiharu Nishiyama
1)

2)

1)

1)

Department of Biological Science and Technology, Tokyo University of Science, Tokyo, Japan, 2)University of Tsukuba, IIIS

WS21-08-O/P

	Difamilast, a selective phosphodiesterase 4 inhibitor, suppresses IL-4 production by basophils andameliorates atopic dermatitis in a murine model
1, 2)
1)
1)
1, 3)
1)
〇 Kazufusa Takahashi , Kensuke Miyake , Junya Ito , Hinano Shimamura , Hajime Karasuyama

1)

Inflammation, Infection, Immunity Laboratory, Advanced Research Institute, Tokyo Medical and Dental University (TMDU), Tokyo, Japan,
Depertment of Human Pathology, Graduate School of Medical and Dental Sciences, Tokyo Medical and Dental University (TMDU), Tokyo,
Japan, 3)Depertment of Medical Science, Graduate School of Medical Sciences, Kitasato University, Kanagawa, Japan2)

WS21-09-O/P

miR-451a suppresses delayed-type hypersensitivity by regulating Th17 differentiation
1, 2)
1)
1)
〇 Takanobu Yoshida , Ken Takashima , Hiroyuki Oshiumi

1)Department of Immunology, Graduate School of Medical Sciences, Faculty of Life Sciences, Kumamoto University, 2)Department of Pediatrics,
Graduate School of Medical Sciences, Kumamoto University
WS21-10-P	Effect of subcutaneous immunotherapy on proliferation of group 2 innate lymphoid cells (ILC2) in an
asthma model〇 Masaya Matsuda, Asuka Hirano, Fumiya Yonezawa, Kazuyuki Kitatani, Takeshi NabeLaboratory of Immunopharmacology, Faculty of Pharmaceutical Sciences, Setsunan University, Hirakata, Japan132

WS21-11-P

Soluble TIM-4 levels in serum are associated with severe asthma phenotype
1, 2)
1)
2)
2, 3)
2)
1)
〇 Yuki Tanabe , Hisaya Akiba , Norihiro Harada , Sonoko Harada , Kazuhisa Takahashi , Sachiko Miyake

1)

Department of Immunology, Juntendo University School of Medicine, Tokyo, Japan, 2)Department of Respiratory Medicine, Juntendo University
School of Medicine, Tokyo, Japan, 3)Atopy (Allergy) Research Center, Juntendo University Graduate School of Medicine, Tokyo, Japan

WS21-12-P

	The inhibition of OVA-induced airway hyperresponsiveness and eosinophilic airway inflammation in tightjunction protein claudin-3-deficient mice
〇 Yumiko Ishii , Ayaka Shiota , Keiko Kan-O , Tomohiro Ogawa , Norio Yamamoto , Seiji Shinozaki , Aimi Ogawa ,Satoru Fukuyama1), Koichiro Matsumoto2), Isamu Okamoto1)
1)

1)

1)

1)

1)

1)

1)

1)

Department of respiratory medicine, Graduate school of medical science, Kyushu university, 2)Department of medicine, Division of oral andmedical management, Fukuoka dental college
WS21-13-P

Nematode ascarosides attenuate mammalian type 2 inflammatory responses〇 Masahiro Kiuchi, Kota Kokubo, Atsushi Onodera, Kiyoshi Hirahara, Toshinori Nakayama
Department of Immunology, Graduate School of Medicine, Chiba University

WS21-14-P

TRPA1 channel mediates cold air-induced aggravation of airway inflammation〇 Yoichi Dotake, Takahiro Matsuyama, Hiromi Matsuyama, Koichi Takagi, Kentaro Machida, Hiromasa Inoue
Department of Pulmonary Medicine, Graduate School of Medical and Dental Sciences, Kagoshima University, Kagoshima, Japan

WS21-15-P

Wdfy4 promotes antigen-specific IgE production in allergic asthma models〇 Yusuke Murakami, Tomoya Narita, Takashi Ishii, Naomi Yamashita
Faculty of Pharmacy, Department of Pharmaceutical Sciences, Musashino University, Tokyo, Japan

WS21-16-P

Confirmation of the inhibitory effect of P2Y6 receptor antagonist on allergic reaction〇 Manabu Nakano

1, 2)

1)

Department of Bioscience and Laboratory Medicine, Hirosaki University Graduate School of Health Sciences, 2)Research Center for Biomedical
Sciences, Hirosaki University Graduate School of Health Sciences
WS21-17-P

A role of eosinophils in oral tolerance for food allergy〇 Shunjirou Kurihara, Masaya Yokota, Kotaro Suzuki, Takahiro Kageyama, Kazuyuki Meguro, Shigeru Tanaka,
Arifumi Iwata, Akira Suto, Hiroshi Nakajima
Department of Allergy and Clinical Immunology, Graduate School of Medicine Chiba University

WS21-18-P

Detection of migration of IgE+ cells from draining lymph node after skin sensitization〇 Mayuko Hashimoto , Yutaka Kusumoto , Takahiro Adachi , Michio Tomura
1)

1)

2)

1)

1)

2)

Laboratory of Immunology Faculty of Pharmacy, Osaka Ohtani University, Osaka, Japan, Medical Research Institute Pathophysiology
Immunology, Tokyo Medical and Dental University, Tokyo, Japan
WS21-19-P

An isolated living environment suppresses papain-induced asthma〇 Takuya Yashiro , Kazuyo Moro
1)

1, 2)

1)

Laboratory for Innate Immune Systems, Department of Microbiology and Immunology, Graduate School of Medicine, Osaka University, Osaka,
Japan, 2)Laboratory for Innate Immune Systems, RIKEN IMS, Yokohama, Japan
WS21-20-P

Environmental enrichment suppresses skin allergic inflammation in mice
1, 2)
1)
1, 2)
1)
2)
1, 2)
〇 Yuki Fujita , Hitoshi Urakami , Kei Nagao , Atsunori Kamiya , Sachiko Miyake , Soichiro Yoshikawa
1)

Department of Cellular Physiology, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, 2)Department of
Immunology, Juntendo University Graduate School of Medicine
WS21-21-P

	Adaptive discrimination between harmful and harmlss antigens in immune system based onmathematical modeling〇 Kana Yoshido , Naoki Honda
1)

1, 2, 3)

1)

Graduate School of Biostudies, Kyoto University, 2)Graduate School of Integrated Sciences for Life, Hiroshima University, 3)Exploratory
Research Center on Life and Living Systems (ExCELLS), National Institutes of Natural Sciences

133December 9
WS22

Hematopoiesis and Immune Environment

WS22-01-O/P

Critical role of N 6-methyladenosine modification deposited by METTL16 in hematopoiesis〇 Masanori Yoshinaga , Michael C Bassik , Osamu Takeuchi
1)

2)

1)

1)

Department of Medical Chemistry, Graduate School of Medicine, Kyoto University, 2)Department of Genetics, Stanford University

WS22-02-O/P

Tracing the evolutionary history of T cells back to invertebrates〇 Yosuke Nagahata , Ryota Kaitani , Yutaka Satou , Hiroshi Kawamoto
1)

1)

2)

1)

1)

2)

Laboratory of Immunology, Institute for Life and Medical Sciences, Kyoto University, Department of Zoology, Graduate School of Science,
Kyoto University
WS22-03-O/P

Akkermansia muciniphila induces chronic extramedullary hematopoiesis through innate immune signals
1, 2)
1, 3)
1, 3)
1)
4)
4, 5, 6)
, Yuhua Li2, 7),〇 Yuxin Wang , Tatsuya Morishima , Maiko Sezaki , Ryo Sato , Gaku Nakato , Shinji Fukuda
Hitoshi Takizawa1, 8)
1)

Laboratory of Stem Cell Stress, International Research Center for Medical Sciences (IRCMS), Kumamoto University, Kumamoto, 2)Zhujiang
Hospital, Southern Medical University, Guangzhou, China, 3)Laboratory of Hematopoietic Stem Cell Engineering, IRCMS, Kumamoto University,
Kumamoto, 4)Gut Environmental Design Group, Kanagawa Institute of Industrial Science and Technology, Kanagawa, 5)Institute for Advanced
Biosciences (IAB), Keio University, Tokyo, 6)Transborder Medical Research Center, University of Tsukuba, Ibaraki, 7)Bioland Laboratory(Guangzhou Regenerative Medicine and Health Guangdong Laboratory), Guangzhou, Guangdong, China, 8)Center for Metabolic Regulation of
Healthy Aging (CMHA), Kumamoto University, Kumamoto
WS22-04-O/P

Single cell genomics revealed critical molecules affecting cell fate of human stem/progenitor cells
1, 2)
1)
1)
1)
3)
〇 Makoto Iwasaki , Joachim Luginguhehl , Yoriko Saito , Ari Itoh-Nakadai , Leonard Shultz ,2)
1)
1)
Akifumi Takaori-Kondo , Jay Shin , Fumihiko Ishikawa
1)

RIKEN Center for Integrative Medical Sciences, Yokohama, Japan, 2)Department of Hematology and Oncology, Kyoto University, Kyoto, Japan,
The Jackson Laboratory, Bar Harbor, ME

3)

WS22-05-O/P

Novel insights into heterogeneity of embryo-derived B cells divided two distinct subsets in adulthood
1)
1, 2)
1)
1)
3)
2)
〇 Keiko Fujisaki , Nanako Okamoto , Aika Otaki , Yuhei Mizunoe , Shogo Okazaki , Chiharu Nishiyama ,1)
Ryo Goitsuka
1)
Division of Cell Fate Regulation, Research Institute for Biomedical Sciences, Tokyo University of Science, 2)Laboratory of Molecular Biology
and Immunology, Department of Biological Science and Technology, Tokyo University of Science, 3)Department of Microbiology, Nihon
University School of DentistryWS22-06-O/P

The function of Polycomb group proteins during B cell development〇 Mayumi Hirakawa, Tomokatsu Ikawa
Tokyo University of Science Research Institute for Biomedical Sciences Division of Immunology and allergy

WS22-07-O/P

BCR-ABL-induced senescence-associated autophagy bring about maintenance of CML stemness〇 Yamato Tanabe , Makoto Kurachi , Tomohisa Baba , Naofumi Mukaida
1)

1)

1)

2)

2)

2)

Department of Molecular Genetics, kanazawa University, Cancer Research Institute, Kanazawa University

WS22-08-O/P

Runx1 and Runx2 inhibit fibrotic conversion of cellular niches for hematopoietic stem cells〇 Yoshiki Omatsu, Takashi Nagasawa
Graduate School of Frontier Biosciences, Osaka University

WS22-09-O/P	Distinct binding properties of integrin adaptors talin1 and kindlin-3 to LFA1 and α4 integrins modulateadhesive responses in static and shear-flow conditions〇 Naoyuki Kondo, Yuji Kamioka, Yoshiki Ikeda, Yoshihiro Ueda, Tatsuo Kinashi
Kansai Medical University

WS22-10-O/P

The role of isolated CD35+ follicular dendritic cells in the differentiation from B cells to IgA+ GL7+ cells〇 Mari Hikosaka-Kuniishi, Toshiyuki Yamane, Doris Narki Tetteh, Hidetoshi Yamazaki
Department of Stem Cell and Developmental Biology, Mie University Graduate School of Medicine

134

WS22-11-P

	5-aminolevulinic acid (5-ALA) synthesis deficient mice display an immune abnormality and reduced
cytokine release〇 Shinichi Saitoh, Yuji Takeda, Saima Sabrina, Mikako Nagashima, Hironobu Asao
Department of Immunology, Yamagata University Faculty of Medicine

WS22-12-P

GATA4 enhances cGAS-STING-dependent production of type I interferons in lupus monocytes〇 Taiga Kuga , Asako Chiba , Gou Murayama , Kosuke Hosomi , Tomoya Nakagawa , Makio Kusaoi , Ken Yamaji ,Naoto Tamura1), Sachiko Miyake2)
1)

2)

1)

2)

2)

1)

1)

1)
Department of Internal Medicine and Rheumatology, Juntendo University Graduate School of Medicine, 2)Departments of Immunology,
Juntendo University Graduate School of Medicine

WS22-13-P

Novel cell fraction of myeloid leukemia in Tet2-deficient mice discovered by single-cell analysis〇 Yurina Miyajima , Erina Furuhata , Tomohiro Miyai , Harukazu Suzuki
1)

1)

2)

1)

1)

Laboratory for Cellular Function Conversion Technology, RIKEN IMS, Yokohama, Japan, 2)Laboratory for Developmental Genetics, RIKEN IMS,
Yokohama, Japan
WS22-14-P

T-cell progenitors retain Mast-cell potential〇 Ryota Kaitani, Yosuke Nagahata, Hiroshi Kawamoto
Laboratory of Immunology, Institute for Life and Medical Sciences, Kyoto university

WS22-15-P

Novel mechanisms for the regulation of Irf8 gene expression during dendritic cell differentiation〇 Takaya Yamasaki, Akira Nishiyama, Tomohiko Tamura
Department of Immunology, Yokohama City University Graduate School of Medicine, Yokohama, Japan

WS22-16-P

The Regnase-1/3-Nfkbiz axis controls hematopoietic lineage priming〇 Takuya Uehata , Daisuke Ori , Masaki Miyazaki , Hiroshi Kawamoto , Osamu Takeuchi
1)

2)

3)

1)

3)

1)

2)

Medical Chemistry, Graduate School of Medicine, Kyoto University, Kyoto, Japan, Graduate School of Science and Technology, Nara Instituteof Science and Technology, Nara, Japan, 3)Institute for Life and Medical Sciences, Kyoto University, Kyoto, Japan
WS22-17-P	Subsecond Rap1 activation by outside-in signaling of LFA1/ICAM1 interactions strengthens L-selectin
mediated rolling of T cells〇 Yuji Kamioka, Yoshihiro Ueda, Naoyuki Kondo, Yoshiki Ikeda, Tatsuo Kinashi
Department of Molecular Genetics, Institute of Biomedical Science, Kansai Medical University, Osaka, Japan

WS22-18-P

Analysis of various human immune responses by applying the human-type artificial lymphoid tissues〇 Yuka Kobayashi, Takeshi Watanabe, Hiroshi Kawamoto
Institute for Life and Medical Sciences, Kyoto University, Kyoto, Japan

WS22-19-P

Micro- and macro-anatomical frameworks of lymph nodes for filtering lymph-borne substances〇 Tomoya Katakai, Madoka Ozawa, Shihori Nakajima
Department of Immunology, Niigata University Graduate School of Medical and Dental Sciences

WS22-20-P	Hepatic ILC1s Lacking IL-7 receptor Arise Independently of Conventional Group 1 ILCs throughParenchymal Niches〇 Takuma Asahi, Koichi Ikuta
Laboratory of Immune Regulation, Department of Virus Research, Institute for Life and Medical Sciences, Kyoto University, Kyoto, Japan

WS22-21-P

Embryo-derived innate-like B cells expressing the J-chain in cardiac fat-associated lymphoid clusters
1, 2)
1)
1)
3)
2)
1)
〇 Nanako Okamoto , Keiko Fujisaki , Yuhei Mizunoe , Shogo Okazaki , Chiharu Nishiyama , Ryo Goitsuka
1)

Division of Cell Fate Regulation, Research Institute for Biomedical Sciences, Tokyo University of Science, 2)Laboratory of Molecular Biology
and Immunology, Department of Biological Science and Technology, Tokyo University of Science, 3)Department of Microbiology, Nihon
University School of DentistryWS22-22-P	Cartilage-degrading cells in the primary ossification center contributes to perinatal bone marrowdevelopment〇 Eriko Sumiya, Shinichiro Sawa
Medical Institute of Bioregulation, Kyushu University, Fukuoka, Japan135

WS22-23-P

	Neural crest-derived mesenchymal cells support thymic regeneration after lethal irradiation〇 Doris Narki Tetteh, Hidetoshi Yamazaki, Mari Hikosaka-Kuniishi
Stem Cell and Developmental Biology, Mie University Graduate School of Medicine, Japan

Dynamic kinetics of fibroblasts during acute oesophageal inflammation

WS22-24-P〇 Kentaro Iwata , Yuya Hagihara , Yoshiaki Takada , Rino Ishihara , Yohei Mikami , Takanori Kanai
1)

2)

1)

1)

1)

1)

1)

Division of Gastroenterology and Hepatology, Department of Internal Medicine, Keio University School of Medicine, Tokyo, Japan., 2)National
Hospital Organization Saitama Hospital, Saitama, Japan

Evolution of thymic involution through the lens of learning theory

WS22-25-P〇 Shuhei Horiguchi , Tetsuya Kobayashi
1)

2)

1)

Graduate School of Information Science and Technology, The University of Tokyo, Tokyo, Japan, 2)Institute of Industrial Science, The Universityof Tokyo, Tokyo, Japan

December 9
WS23

Human Immunology (Immunointervention)

WS23-01-O/P

An atlas of transcribed enhancers across helper T cell diversity for decoding human diseases
1, 2)
3)
1)
4, 5, 6)
, Kazuhiko Yamamoto3),〇 Akiko Oguchi , Akari Suzuki , Shuichiro Komatsu , Chikashi Terao
Yasuhiro Murakawa1, 7, 8, 9)
1)

RIKEN-IFOM Joint Laboratory for Cancer Genomics, RIKEN Center for Integrative Medical Sciences, Yokohama, Japan, 2)Department ofNephrology, Graduate School of Medicine, Kyoto University, Kyoto, Japan, 3)Laboratory for Autoimmune Diseases, RIKEN Center for Integrative
Medical Sciences, Yokohama, Japan, 4)Laboratory for Statistical and Translational Genetics, RIKEN Center for Integrative Medical Sciences,
Yokohama, Japan, 5)Clinical Research Center, Shizuoka General Hospital, Shizuoka, Japan, 6)Department of Applied Genetics, School of
Pharmaceutical Sciences, University of Shizuoka, Shizuoka, Japan, 7)IFOM - the FIRC Institute of Molecular Oncology, Milan, Italy., 8)Institutefor the advanced study of human biology, Kyoto University, Kyoto, Japan, 9)Department of Medical Systems Genomics, Graduate School of
Medicine, Kyoto University, Kyoto, Japan
WS23-02-O/P

Mechanisms of impaired hematopoiesis caused by the IKZF1N159S variant〇 Jingjie Chang, Kazuki Okuyama, Junji Harada, Chengcheng Zou, Ichiro Taniuchi
Integrative Medical Sciences (IMS), RIKEN, Yokohama, Japan

WS23-03-O/P

Actively transcribed regulatory regions drive the genetic risk of rheumatoid arthritis〇 Hiroaki Hatano , Akari Suzuki , Matteo Guerrini , Michihiro Kono , Masahiro Nakano , Akiko Oguchi ,Chikashi Terao4), Yasuhiro Murakawa3), Kazuhiko Yamamoto2), Kazuyoshi Ishigaki1)
1)

2)

2)

1)

2)

3)

1)

Laboratory for Human Immunogenetics, RIKEN Center for Integrative Medical Sciences, Yokohama, Kanagawa, Japan, 2)Laboratory for
Autoimmune Diseases, RIKEN Center for Integrative Medical Sciences, Yokohama, Kanagawa, Japan, 3)Joint Laboratory for Cancer Genomics,
RIKEN Center for Integrative Medical Sciences RIKEN-IFOM, Yokohama, Kanagawa, Japan, 4)Laboratory for Statistical and Translational
Genetics, RIKEN Center for Integrative Medical Sciences, Yokohama, Kanagawa, Japan
WS23-04-O/P

	Establishment of human immune system mice for evaluation of rejection of HLA-depleted cells inregenerative medicine〇 Charlotte Flahou , Natsumi Higashi , Huaigeng Xu , Akitsu Hotta , Bo Wang , Shin Kaneko , Tatsuya Morishima ,Hitoshi Takizawa3), Koji Eto1, 4), Naoshi Sugimoto1)
1)

1)

1)

1)

2)

2)

3)

1)
Department of Clinical Application, Center for iPS Cell Research and Application (CiRA), Kyoto University, Kyoto, Japan, 2)Department of Cell
Growth and Differentiation, Center for iPS Cell Research and Application (CiRA), Kyoto University, Kyoto, Japan, 3)International Research Center
for Medical Sciences (IRCMS), Kumamoto University, Kumamoto, Japan, 4)Department of Regenerative Medicine, Chiba University Graduate
School of Medicine, Chiba, Japan

WS23-05-P

A novel ischemic infraction model using humanized NOG-IL-34 Tg mouse〇 Ikumi Katano, Takeshi Takahashi, Mamoru Ito
CIEA

WS23-06-P

Generation of the novel humanized mice with hemophilia A〇 Akihisa Oda , Masahiro Kitabatake , Noriko Ouji-Sageshima , Shoko Furukawa , Takeshi Kawamura ,Toshikazu Takahashi3), Toshihiro Ito2), Keiji Nogami1)
1)

2)

2)

1)

1)

1)
Department of Pediatrics, Nara Medical University, 2)Department of Immunology, Nara Medical University, 3)Central Institute for Experimental
Animals136

WS23-07-P

	Analysis of the effect of baricitinib on acute lung injury induced by selective human CD25 stimulation inhumanized mice
〇 Shin-Ya Tamechika, Shinji Maeda, Shuntaro Isogai, Tomoyo Maeda, Taio Naniwa, Akio Niimi
Department of Respiratory Medicine, Allergy and Clinical Immunology, Nagoya City University School Medical Sciences, Nagoya City, Japan

WS23-08-O/P	Pathogenic analysis of the idiotypic multicentric Casthleman disease (iMCD)― Aberrant immunoregulatory disorder revealed by the iMCD model mice which was transplanted withpatient’s lymph mode cells ―〇 Kazuyuki Yoshizaki , Yoshikane Kikushige , Takuya Harada , Kazuko Uno , Mitunori Kaneko , Hiroaki Niiro ,Kouichi Akashi5)
1)

2)

2)

3)

4)

5)

1)
SANKEN Osaka University, Osaka, Japan, 2)Kyushu University Hospital, Fukuoka, Japan, 3)Louis Pasteur Medical Research center, Kyoto,
Japan, 4)Suita Tokusyukai Hospital, Osaka, Japan, 5)Kyushu University, Fukuoka, Japan

WS23-09-O/P

Fab fragments against human IgE Cε2 inhibit the binding of IgE to its receptors〇 Hexing Wang , Tomoaki Ando , Toshiaki Maruyama , Cj Okumura , Kumi Izawa , Ayako Kaitani ,Yasuharu Kume1), Koji Tokushige1, 3), Nobuhiro Nakano1), Keiko Maeda1), Ko Okumura 1), Jiro Kitaura1, 3)
1)

1)

2)

2)

1)

1)

1)

Atopy (Allergy) Research Center, Juntendo University Graduate School of Medicine (Tokyo, Japan), 2)Abwiz Bio Inc. (CA, USA), 3)Department of
Science of Allergy and Inflammation, Juntendo University Graduate School of Medicine (Tokyo, Japan)
WS23-10-O/P

Innate IgE exacerbates allergic disease via amplification of ILC2 activation〇 Yasutaka Motomura

1, 2, 3)

, Yohei Maeda4), Masaki Hayama4), Kazuyo Moro1, 2, 3)

1)

Laboratory for Innate Immune Systems, Department of Microbiology and Immunology, Graduate School of Medicine, Osaka University,
Osaka, Japan, 2)Laboratory for Innate Immune Systems, Osaka University Immunology Frontier Research Center (IFReC), 3)Laboratory for Innate
Immune Systems, RIKEN IMS, Kanagawa, Japan, 4)Department of Otorhinolaryngology-Head and Neck surgery, Graduate School of Medicine,
Osaka University, Osaka, Japan
WS23-11-O/P

Withdrawn

WS23-12-P

Transition of antibody titers after the SARS-CoV-2 mRNA vaccine in Japanese healthcare workers〇 Masahiro Kitabatake, Noriko Ouji-Sageshima, Ryutaro Furukawa, Atsushi Hara, Toshihiro Ito
Department of Immunology, Nara Medical University, Nara, Japan

WS23-13-O/P	Quantitative and qualitative differences in HBc-specific CD8 T cells could impact the level of HBsAg in
Hepatitis B patients
1)
2)
1, 3)
1, 4)
1)
〇 Shokichi Takahama , Sachiyo Yoshio , Hirotomo Murakami , Hirofumi Akita , Takuto Nogimori ,Shun Kaneko5), Masayuki Kurosaki5), Yasuhiro Asahina6), Ryotaro Sakamori7), Tetsuo Takehara7), Tatsuya Kanto2),
Takuya Yamamoto1, 4, 8, 9)
1)

Laboratory of Immunosenescence, Center for Vaccine and Adjuvant Research, National Institutes of Biomedical Innovation, Health andNutrition, Osaka, Japan, 2)Department of Liver Diseases, Research Center for Hepatitis and Immunology, National Center for Global Health andMedicine, Tokyo, Japan, 3)Department of Gastroenterological Surgery, Graduate School of Medicine, Osaka University, Osaka, Japan,
4)
Laboratory of Translational Cancer Immunology and Biology, Next-generation Precision Medicine Research Center, Osaka International Cancer
Institute, Osaka, Japan, 5)Department of Gastroenterology and Hepatology, Musashino Red Cross Hospital, Tokyo, Japan, 6)Department of Liver
Disease Control, Tokyo Medical and Dental University, Tokyo, Japan., 7)Department of Gastroenterology and Hepatology, Osaka University
Graduate School of Medicine, Osaka, Japan., 8)The Research Institute for Microbial Diseases, Osaka University, Osaka, Japan., 9)Department of
Virology and Immunology, Graduate School of Medicine, Osaka University, Osaka, Japan
WS23-14-P	Naïve CD4 T cells expressing a high level of CXCR3 increase with age and radiation exposure in atomicbomb survivors〇 Kengo Yoshida , Munechika Misumi , Waka Ohishi , Tomonori Hayashi , Yoichiro Kusunoki
1)

2)

3)

1)

1)

2)

1)

Department of Molecular Biosciences, Radiation Effects Research Foundation, Hiroshima, Department of Statistics, Radiation Effects Research
Foundation, Hiroshima, 3)Department of Clinical Studies, Radiation Effects Research Foundation, Hiroshima

137

WS23-15-P

	Deep immune correlates of COVID-19 disease progression and outcome〇 David Priest , Janyerkye Tulyeu , Jonas Sondergaard , Yuki Togami , Yumi Mitsuyama , Takeshi Ebihara ,Hisatake Matsumoto3), Hiroshi Ogura3), James Wing1, 2)
1)

2)

2)

3)

4)

3)

1)

Laboratory of Human Single Cell Immunology WPI-IFReC, OSAKA UNIVERSITY, Japan, 2)Human Immunology Group, CiDER, OSAKAUNIVERSITY, Japan, 3)Department of Traumatology and Acute Critical Medicine, Osaka University Graduate School of Medicine, Japan,
4)
Division of Trauma and Surgical Critical Care, Osaka General Medical Center, Japan
WS23-16-P

	The dominant immune mechanism for Long-COVID differs in gender
1, 2)
1)
1, 2)
3)
3)
4)
〇 Yayoi Iwamoto , Hiroyuki Yoshitomi , Natsumi Iwasaki , Toyohiro Hirai , Isao Ito , Takao Hashiguchi ,5)
1, 2)Koichi Hirahata , Hideki Ueno
1)
Department of Immunology, Graduate School of Medicine, Kyoto University, Kyoto, Japan, 2)Institute for the Advanced Study of Human Biology(ASHBi), Kyoto University, Kyoto, Japan, 3)Department of Respiratory Medicine, Graduate School of Medicine, Kyoto University, Kyoto, Japan.,
4)
Laboratory of Medical Virology, Institute for Frontier Life and Medical Sciences, Kyoto University, Kyoto, Japan, 5)Hirahata Clinic, Tokyo, Japan

December 9
WS24Tolerance and Immune suppression-2

WS24-01-O/P

PD-1 agonism by anti-CD80 inhibits T cell activation and alleviates autoimmunity〇 Daisuke Sugiura , Il-Mi Okazaki , Takumi Maruhashi , Kenji Shimizu , Naozumi Ishimaru , Taku Okazaki
1)

1)

1)

1)

2)

1)

1)

Laboratory of Molecular Immunology, Institute for Quantitative Biosciences, The University of Tokyo, Tokyo, Japan, 2)Department of Oral
Molecular Pathology, Graduate School of Biomedical Sciences, Tokushima University, Tokushima, Japan

WS24-02-O/P

	CD45 modulation augments CD8 T cell energy metabolism and function in aged mice, reverting
resistance to PD-1 blockade cancer immunotherapy〇 Sara Delghandi , Kenji Chamoto , Yuka Nakajima , Hidetaka Kosako , Tasuku Honjo
1)

1)

1)

2)

1)

1)

Division of Immunology and Genomic Medicine, Center for Cancer Immunotherapy and Immunobiology, Kyoto University Graduate School of
Medicine, 2)Division of Cell Signaling, Fujii Memorial Institute of Medical Sciences, Tokushima University
WS24-03-P

PD-1 is responsible for the control of Th2 responses and allergic gastritis〇 Naoko Ikuta , Masaki Tajima , Yukako Kamita , Hiroshi Hiai , Tasuku Honjo , Akio Ohta
3)

4)

3)

1)

1)

2)

3)

2)

Kyoto Disease Model Institute, Kyoto, Japan., Department of Immunology and Genomic Medicine, Graduate School of Medicine, Kyoto
University, Kyoto, Japan., 3)Department of Immunology, Foundation for Biomedical Research and Innovation at Kobe, Kobe, Japan., 4) Integrated
High-Order Regulatory Systems Division, Center for Cancer Immunotherapy and Immunobiology (CCII), Graduate School of Medicine, Kyoto
University, Kyoto, Japan

WS24-04-P

PD-1 is required for the suppression of inflammatory responses in aged mice
〇 Yoshiro Osaki
Nara Institute of Science Technology Nara Japan

WS24-05-O/P

A novel allergen-specific anergic T cell therapy induced by the blockade of T cell co-stimulation〇 Yui Maehara , Kazuyoshi Takeda
1)

1, 2, 3)

, Koichiro Uchida3), Ko Okumura1, 3, 4)

1)

Department of Biofunctional Microbiota, Juntendo University, 2)Laboratory of Cell Biology, Research Support Center, Graduate School of
Medicine, Juntendo University, 3)Center for Immune Therapeutics and Diagnosis, Juntendo Advanced Research Institute for Health Science,
Juntendo University, 4)Atopy (Allergy) Research Center, Graduate School of Medicine, Juntendo University
WS24-06-P

Extra loop of LAG-3 is dispensable for its inhibitory function〇 Taisuke Narazaki, Daisuke Sugiura, Takumi Maruhashi, Il-Mi Okazaki, Kenji Shimizu, Taku Okazaki
Laboratory of Molecular Immunology, Institute for Quantitative Biosciences, The University of Tokyo, Tokyo, Japan

WS24-07-P

Stable pMHCII serves as the ligand of LAG-3 to trigger its inhibitory function〇 Takumi Maruhashi, Daisuke Sugiura, Il-Mi Okazaki, Kenji Shimizu, Taku Okazaki
Laboratory of Molecular Immunology, Institute for Quantitative Biosciences, The University of Tokyo, Tokyo, Japan

WS24-08-P

	VSIG4/CRIg, a new B7 family ligand, directly regulates early CD8+ T cell activation through its counterreceptor in a narrow window〇 Amrita Widyagarini , Yohei Kawano , Chenyang Zhang , Miyuki Azuma
1)

2)

1)

1)

1)

Department of Molecular Immunology, Graduate School of Medical and Dental Sciences, Tokyo Medical and Dental University, Tokyo, Japan,
Department of Immunology, Graduate School of Biomedical and Health Sciences, Hiroshima University, Hiroshima, Japan

2)

138

WS24-09-O/P

Identification and binding analysis of novel receptors for HLA-G2〇 Hiroshi Watanabe, Kimiko Kuroki, Katsumi Maenaka
Faculty of Pharmaceutical Science, Hokkaido University, Sapporo, Japan

WS24-10-O/P

Abrogation of self-tolerance by self-antigen complexed with MHC class II molecules〇 Hui Jin , Hisashi Arase
1)

1, 2)

1)

Department of Immunochemistry, Research Institute for Microbial Diseases, Osaka University, Osaka, Japan, 2)Laboratory of Immunochemistry,
WPI Immunology Frontier Research Center, Osaka University, Osaka, Japan
WS24-11-O/P

Induction of Regulatory T Cells by Ubiquitinated MHC II〇 Yuko Kozono, Fan Baicheng, Haruo Kozono
Research Institute for Biomedical Sciences, Tokyo University of Sciences, Noda, Chiba, Japan

WS24-12-P

The role of Fcrl5 in autoimmune disease〇 Chisato Ono , Yuta Kochi , Shinya Tanaka , Kazuhiko Yamamoto , Yoshihiro Baba
1)

2)

1)

3)

1)

1)

Division of Immunology and Genome Biology, Department of Molecular Genetics, Medical Institute of Bioregulation, Kyushu University,
Fukuoka, Japan, 2)Department of Genomic Function and Diversity, Medical Research Institute, Tokyo Medical and Dental University, Tokyo,
Japan, 3)RIKEN Center for Integrative Medical Sciences, Kanagawa, Japan
WS24-13-P

Cell death-deficient mice develop T cell exhaustion〇 Takao Seki , Shion Miyoshi , Kenta Moriwaki , Soh Yamazaki , Hiroyasu Nakano
1)

2)

1)

1)

1)

1)

2)

Department of Biochemistry, Toho University School of Medicine, Tokyo, Japan, Department of Respiratory Medicine, Toho University
Graduate School of Medicine, Tokyo, Japan
WS24-14-P

Effects of localization changes of caveolin-1 on Nrf2-HO-1 activation induced by quercetin〇 Fuzuki Hayashi , Miyoko Matsushima , Hikaru Tsuzuki , Moeko Ohara , Nodoka Shimasaki , Ayumi Tajima ,Hinata Taniguchi2), Hina Kawashima1), Sayaka Takagi1), Nanami Yoshida1), Tsutomu Kawabe2)
1)

2)

2)

2)

2)

2)

1)

Department of Medical Technology, Nagoya University School of Health Sciences, Aichi, Japan, 2)Department of Integrated Health Sciences,
Nagoya University Graduate School of Medicine, Aichi, Japan
WS24-15-O/P

IL-18 Regulates Immune Responses Contributing Placental Development and Fetal Growth
1, 2)
1, 2)
1, 2)
2)
1)
〇 Hajime Ino , Yumi Horii , Yasuyuki Negishi , Shunji Suzuki , Rimpei Morita
1)

Department of Microbiology and Immunology, Nippon Medical School, Tokyo, Japan, 2)Department of Gynecology and Obstetrics, Nippon
Medical School, Tokyo, Japan
WS24-16-P

Identification of a scavenger-inducing factor promoting inflammatogenic DAMP clearance
1, 2)
1)
2)
1)
〇 Kento Otani , Jun Tsuyama , Koji Hase , Takashi Shichita

1)
Stroke Renaissance Project,Tokyo Metropolitan Institute of Medical Science,Tokyo,Japan, 2)Keio University Graduate School of Pharmaceutical
Sciences,Tokyo,Japan

WS24-17-O/P	CCR9 inhibition alters tissue distribution of plasmacytoid dendritic cells and leads to hepatic immune
suppression〇 Yuzo Koda, Nobuhiro Nakamoto, Takanori Kanai
Division of Gastroenterology and Hepatology, Department of Internal Medicine, Keio University School of Medicine

WS24-18-P

	Cardiac glycoside regulates immune cell migration by blocking protein-protein interaction between
lysosomal Ragulator complex and Myosin phosphatase-RhoA interacting protein (MPRIP)〇 Tatsunori Jo

1, 2, 3), Hyota Takamatsu1, 2, 3), Atsushi Kumanogoh1, 2, 3)

1)Integrated Frontier Research for Medical Science Division, Institute for Open and Transdisciplinary Research Initiatives, Osaka University,
Suita, Osaka, Japan, 2)Department of Respiratory Medicine and Clinical Immunology, Graduate School of Medicine, Osaka University, Suita,
Osaka, Japan, 3)Department of Immunopathology, WPI, Immunology Frontier Research Center (iFReC), Osaka University, Suita, Osaka, Japan
WS24-19-O/P

AIRE leaves footprints on chromatin for immunological self-tolerance〇 Kenta Horie, Nobuko Akiyama, Taishin Akiyama
Center for Integrative Medical Sciences, Riken, Yokohama, Japan

WS24-20-O/P

CXCR4 defines transit-amplifying cells of medullary thymic epithelial cells〇 Tatsuya Ishikawa

1, 2), Taishin Akiyama 1, 2), Nobuko Akiyama 1)

1)

RIKEN Center for Integrative Medical Sciences, Yokohama, Japan, 2)Graduate School of Medical Life Science, Yokohama City University,
Yokohama, Japan139

December 9
WS25

Cytokines and Chemokines-2

WS25-01-P

Involvement of chemokine receptor CCR4 in DSS-induced colitis model〇 Tatsuma Honzawa , Kazuhiko Matsuo , Osamu Yoshie , Takashi Nakayama
1)

1)

2)

1)

1)

2)

Kindai University Faculty of Pharmacy, Higashi-osaka, Japan, The Health and Kampo Institute, Sendai, Japan

WS25-02-P

Identification of pathogenic Th17 cells in gastrointestinal tract using chemokine receptor deficient mice
〇 Shimpei Ariki, Sotaro Ozaka, Nozomi Sachi, Yomei Kagoshima, Thanyakorn Chalalai, Naganori Kamiyama,
Takashi Kobayashi
Department of Infectious Disease Control Faculty of Medicine, Oita University, Yufu, Japan

WS25-03-O/P	Lactococcus lactis subsp. Cremoris C60 restores T Cell Population in Small Intestinal Lamina Propria in
Aged Interleukin-18 Deficient Mice
〇 Toshio Maekawa

1, 2, 3), Suguru Saito3, 4), Noriko Tsuji1, 2, 3, 5)

1)

Microbiology/Immune Homeostasis, Dept. Pathology and Microbiology, Nihon University, School of Medicine, Tokyo, Japan, 2)iFoodmed.
Inc. Research Inst., Ibaraki, Japan, 3)Cellular and Molecular Engineering, Dept. Life Technology and Science, AIST, 4)Dept. Dentistry, Faculty of
Medicine and Dentistry, University of Alberta, 5)Dept. Food Science, Jumonji University, Saitama, Japan
WS25-04-O/P

The source and function of soluble ST2〇 Pei-Chi Lo , Yasutaka Motomura
1)

1, 2, 3), Kazuyo Moro1, 2, 3, 4)

1)

Graduate School of Medicine, Osaka University, 2)Osaka University Immunology Frontier Research Center (IFReC),, 3)Graduate School of
Frontier Biosciences, Osaka University, 4)RIKEN Center for Integrative Medical Sciences
WS25-05-O/P	Anti-IgE Ab treatment attenuates OVA-Ag-induced neutrophilic airway inflammation and IL-17 productionin the lungs
1, 2)
3)
2, 4)
3)
2, 4)
〇 Kazuyuki Nakagome , Mitsuru Imamura , Masaaki Kawano , Kimito Kawahata , Rie Takagi ,
5)
2, 4)
1, 2)
Hiroaki Harada , Sho Matsushita , Makoto Nagata
1)

Department of Respiratory Medicine, Saitama Medical University, Saitama, Japan, 2)Allergy Center, Saitama Medical University, Saitama,
Japan, 3)Division of Rheumatology and Allergology, Department of Internal Medicine, St Marianna University School of Medicine, Kanagawa.,
4)
Department of Allergy and Immunology, Saitama Medical University, Saitama, Japan, 5)Department of Allergy and Rheumatology, Graduate
School of Medicine, University of Tokyo, Tokyo, Japan
WS25-06-O/P

Suppression of itch sensation by IL-27〇 Daiji Sakata , Yusuke Nomoto , Masahiro Yamamoto , Chisa Nakashima , Kenji Kabashima , Hiroki Yoshida ,Takuro Kanekura5), Hiromitsu Hara1)
1)

1)

2)

3)

3)

4)

1)

Laboratory of Immunology, Department of Infection and Immunity, Graduate School of Medical and Dental Sciences, Kagoshima University,
Department of Immunoparasitology, Division of Infectious Disease, Research Institute for Microbial Diseases, Osaka University, 3)Department of
Dermatology, Graduate School of Medicine and Faculty of Medicine, Kyoto University, 4)Laboratory of Immunology, Department of Biomolecular
Sciences, Faculty of Medicine, Saga University, 5)Department of Dermatology, Graduate School of Medical and Dental Sciences, Kagoshima
University
2)

WS25-07-P

CCR4 involvement in Th2 cell expansion in lymph nodes of atopic dermatitis model mice
〇 Kosuke Kitahata , Kazuhiko Matsuo , Osamu Yoshie , Takashi Nakayama
1)

1)

1)

2)

1)

2)

Kindai University, Health and Kampo InstituteWS25-08-P

IL-9 regulates Tfh cells to control humoral memory responses
1, 2)
1)
1)
1)
1)
1)
〇 Taiki Sato , Ippei Ikegami , Masahiro Yanagi , Shiori Kamiya , Ryuta Kamekura , Mihoko Ohashi ,2)
1)
Atsushi Watanabe , Shingo Ichimiya
1)

Department of Human Immunology, Research Institute for Frontier Medicine, Sapporo Medical University School of Medicine, 2)Department ofThoracic Surgery, Sapporo Medical University School of Medicine

WS25-09-O/P

	Regulation and cell fate of CCR2+ inflammatory monocytes in the development of T cell-dependent
autoimmune arthritis
1, 2)
1, 2)
1)
1)
1)
2)
〇 Hiroki Mukoyama , Yusuke Takeuchi , Daiya Ohara , Hitomi Watanabe , Gen Kondoh , Akio Morinobu ,Keiji Hirota1)
1)

Laboratory of Integrative Biological Science, Institute for Life and Medical Sciences, Kyoto University, Kyoto, Japan, 2)Department ofRheumatology and Clinical Immunology, Graduate School of Medicine, Kyoto University, Kyoto, Japan140

WS25-10-P

	Reduced expression of CX3CR1 in CD14++CD16+ peripheral monocytes is associated with immunologicaland clinical features of patients with systemic lupus erythematosus〇 Keiko Yoshimoto , Katsuya Suzuki , Yumi Ikeda , Noriyasu Seki , Kazuoto Hiramoto , Shuntaro Saito ,Jun Kikuchi1), Hironari Hanaoka1), Kunio Sugahara2), Kenji Chiba2), Tsutomu Takeuchi1), Yuko Kaneko1)
1)

1)

1)

2)

1)

1)

1)
Division of Rheumatology, Department of Internal Medicine, Keio University School of Medicine, 2)Research Unit/Immunology & Inflammation,
Mitsubishi Tanabe Parma Corporation

WS25-11-P

	Tocilizumab treatment of COVID-19, Castleman Disease and Rheumatoid Arthritis: blocking IL-6 improves
pathology in immune diseases with a varying etiologies
1)
1, 2)
3)
〇 Kazuko Uno , Kazuyuki Yoshizaki , Toshio Tanaka
1)

Louis Pasteur Center for Medical Research, Kyoto, Japan, 2)The Institute of Scientific and Industrial Research, SANKEN, Osaka University,
Osaka, Japan, 3)Kinki Central Hospital, Hyogo, Japan

Analysis of IL-6 secretion from synovial fibroblasts related to cell-to-cell interactions

WS25-12-O/P〇 Haruka Takahashi , Zhuohao Yang , Haruka Tsuchiya , Risa Yoshihara , Yumi Tsuchida , Mai Yamagishi ,Yoshitaka Shirasaki2), Sotaro Uemura4), Takashi Funatsu2), Sakae Tanaka5), Tomohisa Okamura1, 6), Keishi Fujio1)
1)

2)

1)

1)

1)

2, 3)

1)

Department of Allergy and Rheumatology, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan, 2)Graduate School of
Pharmaceutical Sciences, The University of Tokyo, Tokyo, Japan, 3)Live Cell Diagnosis, Ltd., Asaka, Japan, 4)Department of Biological Sciences,
Graduate School of Science, The University of Tokyo, Tokyo, Japan, 5)Department of Orthopaedic Surgery, Graduate School of Medicine, The
University of Tokyo, Tokyo, Japan, 6)Department of Functional Genomics and Immunological Diseases, Graduate School of Medicine, The
University of Tokyo, Tokyo, Japan

Protective effect of Recombinant Human Thrombomodulin on Streptozotocin-induced diabetes

WS25-13-O/P

1, 2)
1, 2)
1)
1)
2)
1)
〇 Yuko Okano , Chisa Inoue , Valeria Fridman , Atsuro Takeshita , Kota Nishihama , Taro Yasuma ,
2)
2)
1)
2)
Masaaki Toda , Corina Gabazza , Yutaka Yano , Esteban Gabazza
1)

Department of Diabetes and Endocrinology Mie University Hospital Mie Japan, 2)Department of Immunology Mie University Mie Japan

Recombinant thrombomodulin ameliorates diabetes by inhibition of pancreatic β cell apoptosis

WS25-14-P

1, 2)
2)
1, 2)
2)
1, 2)
〇 Atsuro Takeshita , Chisa Inoue , Yuko Okano , Kota Nishihama , Taro Yasuma ,1)
1)
1)
Valeria Fridman-D'Alessandro , Masaaki Toda , Corina N. D'Alessandro-Gabazza , Yutaka Yano2), Esteban Gabazza1)
1)

Mie University Graduate School of Medicine, Department of Immunology, 2)Mie University Hospital, Department of Diabetes and Endocrinology

DNAM-1 deficiency exacerbates Concanavalin A-induced acute liver injury through neutrophil infiltration

WS25-15-O/P

1, 2)
3, 4)
1, 3, 4)〇 Soichi Matsuo , Tsukasa Nabekura , Akira Shibuya

1)
Department of Immunology, Faculty of Medicine, University of Tsukuba, Japan, 2)Doctoral Program in Medical Science, Graduate School ofComprehensive Human Sciences, University of Tsukuba, Japan, 3)Life Science Center for Survival Dynamics, Tsukuba Advanced Research
Alliance (TARA), University of Tsukuba, Japan, 4)R&D Center for Innovative Drug Discovery, University of Tsukuba, Japan

Role of intrathrombotic CX3CR1-fractalkine axis during resolution on murine deep vein thrombosis model

WS25-16-O/P〇 Mizuho Nosaka, Yuko Ishida, Akihiko Kimura, Yumi Kuninaka, Naofumi Mukaida, Toshikazu Kondo
Department of Forensic Medicine, Wakayama Medical University
WS25-17-O/P

	CD122-selective IL/2/antiIL-2 complex enhances the synergistic potentiation in the innate immunity andmemory T cells resulting strong anti-tumor effect〇 Kanako Shimizu, Masami Kawamura, Shin-Ichiro Fujii
RIKEN Center for Integrative Medical Sciences, Yokohama, Japan

December 9
WS26

T Cell activation and responses (human and Vitro)

WS26-01-O/P

Composition of the UBASH3A signalosome emphasizes its negative regulatory function in TCR signaling〇 Daiki Mori , Bernard Malissen
1)

2)

1)

Regulation of Host Defense Team, Division of Microbiology and Immunology, Center for Infectious Disease Education and Research, Osaka
University, 2)Centre d'Immunologie de Marseille-Luminy, Aix-Marseille University141

WS26-02-O/P

Regulation of the TNFR family co-signaling by TNF-related recombinant proteins〇 Takanori So , Ayaka Sato , Hodaka Nagai , Mitsuki Azuma , Nagito Shibui , Wakana Imai , Masashi Morita ,Naoto Ishii2)
1)

1)

1)

1)

1)

1)

1)

1)

Laboratory of Molecular Cell Biology, Graduate School of Medicine and Pharmaceutical Sciences, University of Toyama, 2)Department ofMicrobiology and Immunology, Tohoku University Graduate School of Medicine
WS26-03-O/P

CD62L expression is regulated by the states of energy metabolism〇 Koji Kitaoka, Maiko Hajime, Yasuharu Haku, Kenji Chamoto, Tasuku Honjo
Division of Immunology and Genomic Medicine, Center for Cancer Immunotherapy and Immunobiology, Kyoto University Graduate School

WS26-04-O/P	Robust TCR signals control epigenetic conversion of conventional T cells to regulatory T cells throughmTORC1-dependent expression of TET proteins〇 Tomohide Kinoshita , Mai Ohno , Norihito Hayatsu , Reiko Ohnishi , Akira Nakajima , Shohei Hori
1)

1)

2)

2)

1)

1, 2)

1)

Laboratory for Immunology and Microbiology, Graduate School of Pharmaceutical Sciences, The University of Tokyo, Tokyo, Japan, 2)RIKEN
Center for Integrative Medical Sciences, Tokyo, Japan

WS26-05-O/P

Dynamic B-pocket remodeling is a basis for HLA class I molecules to bind peptides and lipopeptides
1, 2)
1, 2)
1, 2)
〇 Minori Asa , Daisuke Morita , Masahiko Sugita

1)
Laboratory of Cell Regulation, Institute for Life and Medical Sciences, Kyoto University, 2)Laboratory of Cell Regulation and Molecular Network,
Graduate School of Biostudies, Kyoto University

WS26-06-O/P

Binding of the CD4/CD8 coreceptor to an MHC molecule positively modulates CAR-T cell response〇 Hiroaki Machiyama , Ei Wakamatsu , Arata Takeuchi , Hitoshi Nishijima , Masae Furuhata , Hiroko Toyota ,Maksim Mamonkin2), Malcolm K Brenner2), Tadashi Yokosuka1)
1)

1)

1)

1)

1)

1)

1)

Department of Immunology, Tokyo Medical University, Tokyo, Japan, 2)Center for Cell and Gene Therapy, Baylor College of Medicine, Houston,
TX, US

WS26-07-O/P	SCD2-mediated cooperative activation of IRF3-IRF9 regulatory circuit controls type I interferontranscriptome in CD4+ T cells〇 Toshio Kanno, Yusuke Endo, Takahiro Nakajima
Kazusa DNA Research InstituteWS26-08-O/P

Generation of CTLs from iPSCs transduced with TCR genes: development of “TCR cassette” method〇 Seiji Nagano , Koji Terada , Yasutoshi Agata , Hiroshi Kawamoto
1)

1)

2)

2)

1)

2)

Kyoto University, Kyoto, Japan, Shiga University of Medical Science, Shiga, Japan

WS26-09-O/P	Analysis of HLA-class-I unrestricted T cell receptors obtained from tumor infiltrating lymphocytes ofbreast cancer patients〇 Abdul Hayee, Satoshi Yamaguchi, Hiroshi Hamana, Kiyomi Shitaoka, Eiji Kobayashi, Tatsuhiko Ozawa,
Ha Thi Viet My, Atsushi Muraguchi, Hiroyuki Kishi
Department of Immunology, Faculty of Medicine, Academic Assembly, University of Toyama

WS26-10-P

Dynamics of the PI3K signaling pathway through the cytosolic domain of ICOS
〇 Ei Wakamatsu, Hiroaki Machiyama, Hiroko Toyota, Masae Furuhata, Hitoshi Nishijima, Arata Takeuchi,
Tadashi Yokosuka
Department of Immunology, Tokyo Medical University, Tokyo, Japan

WS26-11-P

Regulation of OX40 co-signaling by OX40 ligand-mannose-binding lectin fusion protein〇 Ayaka Sato , Takanori So , Mitsuki Azuma , Hodaka Nagai , Masashi Morita , Yuko Okuyama , Naoto Ishii
1)

1)

1)

1)

1)

2)

2)

1)

Laboratory of Molecular Cell Biology, Graduate School of Medicine and Pharmaceutical Sciences, University of Toyama, Toyama, Japan,
Department of Microbiology and Immunology, Tohoku University Graduate School of Medicine, Sendai, Japan2)

WS26-12-P

Activation of the TNFR co-signaling pathway by single-chain TNF-ligand recombinant proteins
1)
1)
1)
1)
1)
1)
1)
〇 Hodaka Nagai , Takanori So , Mitsuki Azuma , Ayaka Sato , Nagito Shibui , Sayaka Ogawara , Yuta Tsutsui ,Masashi Morita1), Naoto Ishii2), Shimpei Matsuyama1), Ayano Suzuki1)
1)

Laboratory of Molecular Cell Biology, Graduate School of Medicine and Pharmaceutical Sciences, University of Toyama, Toyama, Japan,
Department of Microbiology and Immunology, Tohoku University Graduate School of Medicine, Sendai, Japan

2)

142

WS26-13-P

Dissociation of LAG-3 Cluster from TCR-Microclusters by Immune Checkpoint Blockade〇 Takashi Saito, Akiko Hashimoto-Tane
Lab. Cell Signaling, RIKEN Center for Integrative Medical Sciences, Yokohama, Japan

WS26-14-P

SATB1-dependent mitochondrial ROS production controls TCR signaling in CD4 T cells〇 Taku Kuwabara, Marii Ise, Taku Naito, Yuriko Tanaka, Motonari Kondo
Department of Molecular Immunology, Toho University School of Medicine, Tokyo, Japan

WS26-15-P	
Coccomyxa sp. KJ extracts affects the fate of T cells stimulated by toxic shock syndrome toxin-1, asuperantigen secreted by Staphylococcus aureus〇 Satoko Komatsu , Shino Ohshima , Hirofumi Kashiwagi , Yumiko Goto , Yusuke Ohno , Soga Yamada ,Akiko Kanno1), Tomoka Shimizu2), Toshiro Seki4), Atsushi Yasuda4), Hitoshi Kuno1), Yoshie Kametani2, 5)
1)

2)

3)

3)

2)

2)

1)

DENSO CORPORATION, Aichi, Japan, 2)Department of Molecular Life Science, Division of Basic Medical Science, Tokai University School of
Medicine, Kanagawa, Japan, 3)Department of Obstetrics and Gynecology, Tokai University School of Medicine, Kanagawa, Japan, 4)Department
of Internal Medicine, Division of Nephrology, Endocrinology and Metabolism, Tokai University School of Medicine, Kanagawa, Japan, 5)Instituteof Advanced Biosciences, Tokai University, Kanagawa, Japan
WS26-16-P

	Selection of highly responsive TCRs by analysis combining the expression of multiple markers on
BW5147.3 T cells〇 Thi Viet My Ha , Hiroshi Hamana , Eiji Kobayashi , Ozawa Tatsuhiko , Son Tung Dang , ABDUL Hayee ,Hiroyuki Kishi1)
1)

1)

1)

1)

2)

1)

1)

Department of Immunology, Faculty of Medicine, Academic Assembly, University of Toyama, 2)Department of Pathology, Faculty of Medicine,
University of Toyama
WS26-17-P

A molecular basis for specific recognition of lipopeptides by TCRs
〇 Daisuke Morita, Masahiko Sugita
Lab. of Cell Regulation, Institute for Life and Medical Sciences, Kyoto university, Kyoto, Japan

WS26-18-P

	A biomimetic five-module chimeric antigen receptor (5MCAR) designed forantigen-specific therapy in
type1 diabetes
1, 2)
1)
2)
2)
2)
1)
〇 Shio Kobayashi , Martin A. Thelin , Heather L. Parrish , Neha R. Deshpande , Mark S. Lee , Alborz Karimzadeh ,Monika A. Niewczas3, 4), Michael S. Kuhns2, 5, 6, 7), Thomas Serwold1)1)Section of Immunobiology, Research Division, Joslin Diabetes Center, Harvard Medical School, Boston, MA, USA, 2)Department of
Immunobiology, The University of Arizona College of Medicine, Tucson, AZ, USA, 3)Harvard Catalyst – Biostatistical Consulting (Joslin Diabetes
Center site), Boston, MA, USA, 4)Section on Genetics and Epidemiology, Research Division, Joslin Diabetes Center, Harvard Medical School,
Boston, MA, USA, 5)The BIO-5 Institute, The University of Arizona College of Medicine, Tucson, AZ, USA, 6)The Arizona Center on Aging, The
University of Arizona College of Medicine, Tucson, AZ, USA, 7)The University of Arizona Cancer Center, Tucson, AZ, USA
WS26-19-P

	Development of a model to predict abatacept responsiveness in established RA by CD4+ Foxp3+
regulatory T cell phenotype in peripheral blood〇 Shuntaro Isogai, Shinji Maeda, Taio Naniwa, Akio Niimi
Nagoya city University School Medical Sciences Department of Respiratory Medicine, Allergy and Clinical Immunology

WS26-20-P	Estimation of sensitization status in renal transplant recipients by assessing indirect pathway CD4+
T-cells response to donor cell-pulsed dendritic cell
〇 Kenta Iwasaki
Department of Kidney Diseases and Transplant Immunology, Aichi Medical University School of Medicine

WS26-21-P

Rapid cloning of antigen-specific T-cell receptors by applying T cell cis-activation〇 Eiji Kobayashi , Tatsuhiko Ozawa , Kazuto Tajiri , Seisuke Kusano , Shigeyuki Yokoyama , Atsushi Muraguchi ,Hiroyuki Kishi1)
1)

1)

2)

3)

3)

1)

1)

Department of Immunology, University of Toyama, Toyama, Japan, 2)The Third Department of Internal Medicine, University of Toyama, Toyama,
Japan, 3)RIKEN Cluster for Science, Technology and Innovation Hub, Yokohama, Japan

WS26-22-P

Identification of T cells responding to mycobacterial lipids
1, 2)
1, 2)
3)
4)
1, 2)
〇 Yuki Sakai , Xiuyuan Lu , Yoshihiko Hoshino , Takashi Yoshiyama , Sho Yamasaki

1)
Department of Molecular Immunology, Research Institute for Microbial Diseases, Osaka University, Suita, Osaka, Japan, 2)Laboratory of
Molecular Immunology, Immunology Frontier Research Center (iFReC), Osaka University, Suita, Osaka, Japan, 3)Fukujuji Hospital, Japan AntiTuberculosis Association, Matsuyama, Kiyose, Tokyo, Japan., 4)Department of Mycobacteriology, Leprosy Research Center, National Institute of
Infectious Diseases, Aoba, Higashi-Murayama, Tokyo, Japan143

WS26-23-P	Effects of radiation exposure on the relationship between intracellular ROS of blood cells and immunerelated cell frequencies in atomic bomb survivors〇 Tomonori Hayashi , Naohiro Kato , Keiko Furudoi , Seishi Kyoizumi , Kyoji Furukawa , Misa Imaizumi ,Ayumi Hida5), Waka Ohishi6)
1)

2)

3)

1)

4)

5)

1)

Dept. Molecular Biosciences, RERF, 2)Dept. Statistics, RERF, 3)Biosample Research Center, RERF, 4)Biostatistics Center, Kurume University,
Dept. Nagasaki Clinical Studies, 6)Dept. Hiroshima Clinical Studies

5)

WS26-24-P

	High-throughput sequencing of the cancer patients' TCR repertoire at the single-cell level〇 Hidetaka Tanno
Tokyo Metropolitan Institute of Medical Science

December 9
WS27

Tumor Microenvironment, Metabolism

WS27-01-P

	Glucomannan Polysaccharide from Mycelia of Agaricus blazei Murrill Inhibits the Expression of Immune
Checkpoint Molecules and Axl receptor〇 Hajime Kobori , Taro Yasuma , Masaaki Toda , Taira Ikeo , Jing Wu , Toshio Mori , Hirofumi Hirai
Hirokazu Kawagishi3), Corina N. D'Alessandro-Gabazza2), Esteban C. Gabazza2)
1)

2)

2)

3)

3)

3)

3, 4, 5),

1)

Iwade Research Institute of Mycology Co., Ltd, Tsu, Mie, Japan, 2)Department of Immunology, Mie University School of Medicine, Tsu, Mie,
Japan, 3)Department of Applied Biological Chemistry, Faculty of Agriculture, Shizuoka University, Shizuoka, Japan., 4)Research Institute of Green
Science and Technology, Shizuoka University, Shizuoka, Japan., 5)Graduate School of Science and Technology, Shizuoka University, Shizuoka,
Japan
WS27-02-P

	Modulation of Tumor Immune Microenvironment by Depleting Intratumoral Iron with Polymeric Iron
Chelators
1, 2)
1, 2)
3)
4)
2)
1, 2)
〇 Haochen Guo , Takahiro Nomoto , Hiroaki Kino , Jun Ishihara , Makoto Matsui , Yi-Jung Sung ,Nobuhiro Nishiyama1, 2, 3)
1)

Department of Life Science and Technology, Tokyo Institute of Technology, 2)Laboratory for Chemistry and Life Science, Institute of Innovative
Research, Tokyo Institute of Technology, 3)Innovation Center of NanoMedicine (iCONM), Kawasaki Institute of Industrial Promotion, 4)Faculty ofEngineering, Imperial College London
WS27-03-P

	Interleukin 4 Induced 1 (IL4I1) reorganizes tumor immune microenvironment in a mouse melanoma model
1, 2)
1)
1)
1, 2)
〇 Shiho Hirose , Tetsuo Mashima , Kunbai En , Hiroyuki Seimiya

1)
Division of Molecular Biotherapy, Cancer Chemotherapy Center, Japanese Foundation for Cancer Research, 2)Department of Computational
Biology and Medical Sciences, Graduate School of Frontier Sciences, The University of Tokyo

WS27-04-P	Spermidine-derived fatty acid oxidation regulates T cell differentiation and function in cancer
immunotherapy
1)
1, 2)
1)
3)
2, 4)
1)
〇 Aprilia Maharani , Muna Al-Habsi , Kenji Chamoto , Toshihiko Ogura , Sidonia Fagarasan , Tasuku Honjo

1)
Department of Immunology and Genomic Medicine, Kyoto University Graduate School of Medicine, Kyoto, Japan, 2)Division of Integrated
High-Order Regulatory Systems, Center for Cancer Immunotherapy and Immunobiology, Kyoto University Graduate School of Medicine, Kyoto
University, Kyoto, Japan, 3)Department of Developmental Neurobiology, Institute of Development, Aging and Cancer, Tohoku University, Miyagi,
Japan, 4)Laboratory for Mucosal Immunity, Center for Integrative Medical Sciences, RIKEN Yokohama Institute, Yokohama, Japan

WS27-05-P

	cDC1 accumulation in the tumor microenvironment by mXCL1-V21CA59C enhances CD8+ T cell priming
and antitumor immunity〇 Kazuhiko Matsuo , Momo Kamei , Shiki Takamura , Takashi Nakayama
1)

1)

2)

1)

1)

2)

Division of Chemotherapy, Kindai Univerisity Faculty of Pharmacy, Department of Immunology, Kindai Univerisity Faculty of Medicine

WS27-06-P

	Ropeginterferon alfa-2b activates T lymphocytes to exhibit antitumor activity and induces tumor-specificmemory immunity〇 Yasuhiro Nakashima, Kazuki Sakatoku, Joji Nagasaki, Hirohisa Nakamae, Masayuki Hino
Hematology, Graduate School of Medicine, Osaka Metropolitan University, Osaka, Japan144

WS27-07-P

	ILC2-derived OX40L-OX40 signal promotes cytotoxic CD8+ T cell-mediated antitumor immunity in murine
melanoma
1)
1)
1)
1)
1)
1, 2)
〇 Yuko Okuyama , Akira Okajima , Nao Sakamoto , Ryuto Tanabe , Ayaka Hashimoto , Atsuko Asao ,
1)
1)
1)
1)
Ziying Yang , Akihisa Kawajiri , Takeshi Kawabe , Naoto Ishii
1)
Department of Microbiology and Immunology, Tohoku University Graduate School of Medicine, Miyagi, Japan, 2)Department of Disaster Public
Health, International Research Institute of Disaster Science, Tohoku University, Miyagi, Japan

WS27-08-P

	Clec4A4 acts as negative immune checkpoint regulator expressed on conventional dendritic cells tosuppress tumor immunity〇 Tomofumi Uto, Tomohiro Fukaya, Moe Tominaga, Katsuaki Sato
Division of Immunology, Department of Infectious Diseases, Faculty of Medicine, University of Miyazaki

WS27-09-P

Intra-tumor cell infection with Salmonella enhances anti-tumor immunity〇 Yutaka Horiuchi, Sara Hatazawa, Yukie Ando, Akihiro Nakamura, Takashi Murakami
Dept. Microbiol., Saitama Med. Univ.

WS27-10-O/P

	Combination immunotherapy targeting stearoyl-CoA desaturase 1 (SCD1) with immunosuppressive activity
1, 2, 3), Tomonori Yaguchi1, 4), Akiko Kubo5), Takashi Iwata1, 3), Kenji Morii1, 4), Daiki Kato1), Shigeki Ohta1, 6),〇 Yuki Katoh
Makoto Suematsu5), Yutaka Kawakami1, 6)
1)Division of Cellular Signaling, Institute for Advanced Medical Research, Keio University School of Medicine, 2)Division of Anatomical Science,
Department of Functional Morphology, Nihon University School of Medicine, 3)Department of Obstetrics and Gynecology, Keio University
School of Medicine, 4)Department of Immunology and Genomic Medicine, Center for Cancer Immunotherapy and Immunobiology(CCII),
Graduate School of Medicine, Kyoto University, 5)Department of Biochemistry, Keio University School of Medicine, 6)Department of Immunology,
School of Medicine, International University of Health and Welfare
WS27-11-O/P	A novel immunotherapy using CCL19-expressing allogeneic mesenchymal stromal cells exert anti-tumor
effect by increasing CD103+ CD8+ T cells〇 Yuichi Iida, Mamoru Harada
Department of Immunology, Faculty of Medicine, Shimane University

WS27-12-P

	Regulation of pro-tumorigenic cytokines by the activation of Ca2+-activated K+ channel KCa3.1 in THP-1derived M2 macrophages〇 Susumu Ohya, Miki Matsui, Kyoko Endo

Department of Pharmacology, Graduate School of Medical Sciences, Nagoya City University, Nagoya, Japan
WS27-13-O/P

Metabolic adaptation of cancer cells to escape from immune-editing process〇 Sisca Ucche , Soichiro Sasaki , Kazuyoshi Takeda , Yoshihiro Hayakawa
1)

1)

2)

1)

1)

2)

Section of Host Defences, Institute of Natural Medicine, University of Toyama, Laboratory of Cell Biology, Graduate School of Medicine,
Juntendo University
WS27-14-O/P	Spermidine activates Mitochondrial trifunctional complex MTP leading to enhanced fatty acid oxidation
FAO in CD8+ T cells and stronger anti-tumor immunity in combination PD-1 blockade
1, 2, 3)
, Kenji Chamoto1), Norimichi Nomura4), Ken Matsumoto5), Kazuhiko Sonomura6, 7),〇 Muna Al-Habsi
8)
Baihao Zhang , Yuki Sugiura9), Toshihiko Ogura5), Sidonia Fagarasan3, 8), Tasuku Honjo1)
1)
Division of Immunology and Genomic Medicine, Center for Cancer Immunotherapy and Immunobiology, Kyoto University Graduate School of
Medicine, Kyoto, Japan, 2)National Genetic Center, Ministry of Health, Muscat, Oman, 3)Division of Integrated High-Order Regulatory Systems,
Center for Cancer Immunotherapy and Immunobiology, Kyoto University Graduate School of Medicine, Kyoto University, Kyoto, Japan,
4)
Department of Cell Biology, Graduate School of Medicine, Kyoto University, Kyoto, Japan, 5)Department of Developmental Neurobiology,
Institute of Development, Aging and Cancer, Tohoku University, Miyagi, Japan, 6)Center for Genomic Medicine, Graduate School of Medicine,
Kyoto University, Kyoto, Japan, 7)Life Science Research Center, Technology Research Laboratory, Shimadzu Corporation, Kyoto, Japan.,
8)
Laboratory for Mucosal Immunity, Center for Integrative Medical Sciences, RIKEN Yokohama Institute, Yokohama, Japan, 9)Department ofBiochemistry and Integrative Biology, Keio University, Tokyo, Japan145

WS27-15-P

	Type 1 conventional dendritic cells of bone marrow assist the progression of multiple myeloma andconsist of tumor microenvironment in the transplanted Vk*MYC mouse model
1, 2, 3)
, Shogo Tsuda1), Tomoki Takubo1), Haruka Toyoshima1), Miya Yoshino1), Tsuneyasu Kaisho4),〇 Sayaka Suzuki
2)
Tetsuya Fukuda , Koji Tokoyoda1)
1)Division of Immunology, School of Life Science, Faculty of Medicine, Tottori University, Yonago, Japan, 2)Department of Hematology, Tottori
University Hospital, Yonago, Japan, 3)Division of Clinical Laboratory Medicine, Department of Multidisciplinary Internal Medicine, School of
Medicine, Tottori University Faculty of Medicine, Yonago, Japan, 4)Department of Physiological Regulation Mechanisms, Institute of Advanced
Medicine, Wakayama Medical University, Wakayama, Japan

WS27-16-O/P	Single-cell RNA-seq analysis of human tumor infiltrating T cells across multiple tumor types to discoverpotential targets for combination immunotherapy
1)
1)
1)
1)
1)
〇 Yoshinobu Koguchi , Tanisha Christie , Venkatesh Rajamanickam , Noah Simons , Wesley Rosales ,Laura Seestaller Wehr2), Niranjan Yanamandra2), Sue Griffin2), James Smothers2), Johanna Kaufmann3),
Brady Bernard1), William Redmond1)
1)

Earle A. Chiles Research Institute, Providence Cancer Institute, Portland, OR, USA, 2)Immuno-Oncology & Combinations Research Unit,
GlaxoSmithKline, Collegeville, PA, USA, 3)Codagenix, Farmingdale, NY, USA
WS27-17-P

	Combined effects of immune checkpoint blockers, a CD40 agonistic antibody, and a CSF1 receptor
inhibitor on pancreatic cancer in mice
1)
1)
2)
1, 3)
1, 4)
1)
〇 Juri Ichikawa , Hiroshi Okuda , Shingo Kato , Daisuke Kurotaki , Wataru Kawase , Haruka Yoshida ,Tomohiko Tamura1)
1)

Department of Immunology, Yokohama City University Graduate School of Medicine, Yokohama, Japan, 2)Department of Gastroenterology andHepatology, Yokohama City University Graduate School of Medicine, Yokohama, Japan, 3)Laboratory of Chromatin Organization in Immune Cell
Development, International Research Center for Medical Sciences, Kumamoto University, Kumamoto, Japan, 4)Department of Cancer Genomics,
Kanagawa Cancer Center Research Institute, Yokohama, Japan
WS27-18-P

	Mycobacterium Tuberculosis-specific Tbet+ CD4+ memory T cells contribute to trained immunity against
cancer and viral infection
1, 2, 3)
, Nobuyoshi Kobayashi4), Yuta Ohira4), Kou Hioki1), Tomoya Hayashi1, 2, 3), Michelle S.J. Lee5),〇 Burcu Temizoz
4)Takayuki Horii , Cevayir Coban3, 5, 6), Kouji Kobiyama1, 2, 3), Ken J. Ishii1, 2, 3, 6)
1)
Division of Vaccine Science, The Institute of Medical Science, The University of Tokyo, Tokyo, Japan, 2)Center for Adjuvant and Vaccine
research, National Institutes of Biomedical Innovation, Health and Nutrition (NIBIOHN), Osaka, Japan, 3)International Vaccine Design
Center (VDesC), The Institute of Medical Science (IMSUT), The University of Tokyo, Tokyo, Japan, 4)Central Research Laboratories, Zeria
Pharmaceutical Co., Ltd., Kumagaya-shi, Saitama, Japan, 5)Division of Malaria Immunology, Department of Microbiology and Immunology,
The Institute of Medical Science (IMSUT), The University of Tokyo, Tokyo, Japan, 6)WPI Immunology Frontier Research Center (IFReC), Osaka
University, Osaka, Japan

WS27-19-P

Extracellular low pH in myeloma microenvironments induce tolerogenic dendritic cells〇 Mariko Ishibashi, Rimpei Morita
Nippon Medical School

WS27-20-O/P

IFN-α/β-mediated neuropeptide signaling augments malignancy of colon cancer cells
1)
1, 2)
1, 2)
1, 2)
1, 2)
1, 2)
〇 Hidemitsu Kitamura , Huihui Xiang , Yujiro Toyoshima , Naoki Okada , Shuhei Kii , Ko Sugiyama ,
3)
3)
4)
5)
6)
Toshihiro Nagato , Hiroya Kobayashi , Kazuho Ikeo , Shinichi Hashimoto , Mishie Tanino , Akinobu Taketomi2)
1)

Division of Functional Immunology, Institute for Genetic Medicine, Hokkaido University, Sapporo, Japan, 2)Department of Gastroenterological
Surgery I, Hokkaido University Graduate School of Medicine, Sapporo, Japan, 3)Department of Pathology, Asahikawa Medical University,
Asahikawa, Japan, 4)DNA Data Analysis Laboratory, National Institute of Genetics, Mishima, Japan, 5)Department of Molecular Pathophysiology,
Institute of Advanced Medicine, Wakayama Medical University, Wakayama, Japan, 6)Department of Surgical Pathology, Asahikawa Medical
University, Asahikawa, Japan
WS27-21-P

SerpinB9, a hypoxic response-related molecule responsible for immunotherapy resistance〇 Mamoru Harada, Yuichi Iida, Hitoshi Kotani
Department of Immunology, Faculty of Medicine, Shimane University, Izumo, Shimane, Japan

WS27-22-P

	Comprehensive analyses of immune profile in tumor-microenvironment of tongue squamous cell
carcinoma〇 Pissacha Daroonpan, Ryo Ouchi, Miyuki Azuma
Department of Molecular Immunology, Tokyo Medical and Dental University, Tokyo, Japan

146

Immunosuppression-elicited Galectin-7 is a crucial metastatic enhancer of squamous cell carcinoma

WS27-23-O/P

1)
2)
1, 3)
1)
4)
3)
〇 Jianbo An , Yushi Nagaki , Midori Hoshizaki , Tomokazu Yamaguchi , Yuta Kuze , Yumiko Imai ,2)
4)1)
Satoru Motoyama , Yutaka Suzuki , Keiji Kuba
1)

Department of Biochemistry and Metabolic Science, Akita University Graduate School of Medicine, Akita, Japan, 2)Department of Surgery,
Akita University Graduate School of Medicine, Akita, Japan, 3)Laboratory of Regulation of Intractable Infectious Diseases, National Institute of
Biomedical Innovation, Health and Nutrition, Osaka, Japan, 4)Department of Medical Genome Sciences, Graduate School of Frontier Sciences,
The University of Tokyo, Chiba, Japan
WS27-24-O/P	A novel prognostic gene signature of amino acid metabolism pathways under lung adenocarcinoma
tumor immune microenvironment〇 Huihui Xiang , Rika Kasajima , Sasada Tetsuro , Yohei Miyagi
1)

1)

2)

1)

1)

Molecular Pathology & Genetics Division, Kanagawa Cancer Center Research Institute, Yokohama, Japan, 2)Division of Cancer Immunotherapy,
Kanagawa Cancer Center Research Institute, Yokohama, Japan

Establishment of Anti-Estrogenic Therapy targeting IL-34 in Triple-Negative Breast Cancer

WS27-25-P〇 Nabeel Kajihara, Ken-Ichiro Seino
Division of Immunobiology, Graduate School of Medicine, Hokkaido University, Japan

Integrated multiomics profiling identifies the differentiation program of regulatory T cells in human tumors

WS27-26-P

1)
1)
1, 2)
1)
1)
3)
〇 Takuma Irie , Kota Itahashi , Junichiro Yuda , Shogo Kumagai , Tokiyoshi Tanegashima , Yi-Tzu Lin ,
1)
1)
1, 3)
Sho Watanabe , Shohei Koyama , Hiroyoshi Nishikawa
1)

Division of Cancer Immunology, Research Institute/Exploratory Oncology Research & Clinical Trial Center (EPOC), National Cancer Center,
Department of Hematology, National Cancer Center Hospital East, 3)Department of Immunology, Nagoya University Graduate School of Medicine

2)

The symbiotic system in the tumor microenvironment that supports tumor progression

WS27-27-P〇 Xiaoyun Li , Zhengtao Xiao , Jason Locasale , Isabel Lopez-Mejia , Lluis Coll , Ping-Chih Ho
1)

2)

2)

3)

1)

3)

1)

2)

Ludwig Institute for Cancer Research Lausanne, University of Lausanne, Lausanne, Switzerland, Department of Pharmacology and Cancer
Biology, Duke University School of Medicine, Durham, USA, 3)Center for Integrative Genomics, University of Lausanne, Lausanne, Switzerland

December 9
WS28

Infection and Immunity III

WS28-01-O/P

	Therapeutic efficacy of monoclonal antibodies and antivirals against SARS-CoV-2 Omicron variants in thehamster model
1, 2)
1)
1, 2)
1, 2)
1)
1, 2)
1, 2)
〇 Ryuta Uraki , Maki Kiso , Masaki Imai , Seiya Yamayoshi , Mutsumi Ito , Michiko Ujie , Yuri Furusawa ,1)
1)
1)
1, 2, 3)
Atsuhiro Yasuhara , Kiyoko Iwatsuki-Horimoto , Yuko Sakai-Tagawa , Yoshihiro Kawaoka
1)
Division of Virology, Institute of Medical Science, University of Tokyo, 2)The Research Center for Global Viral Diseases, National Center
for Global Health and Medicine Research Institute, 3)Department of Pathobiological Sciences, School of Veterinary Medicine, University of
Wisconsin-Madison

WS28-02-O/P

Acquisition of resistance to wild-type spike-immune sera by emerging SARS-CoV-2 variants
1, 2)
1, 2)
1, 2)
1, 2)
1, 2)
〇 Yafei Liu , Hui Jin , Wataru Nakai , Masako Kohyama , Hisashi Arase1)
Department of Immunochemistry, Research Institute for Microbial Diseases, Osaka University, Japan, 2)Laboratory of Immunochemistry, WPI
Immunology Frontier Research Center, Osaka University, Japan

WS28-03-O/P

The SARS-CoV-2 Omicron BA.1 spike G446S potentiates antiviral T cell immunity〇 Chihiro Motozono , Mako Toyoda , Hiroshi Hamana , Keiko Udaka , Hiroyuki Kishi , Takamasa Ueno
1)

1)

2)

3)

2)

1)

1)

2)

Division of infection and immunity, Joint research center for Human Retrovirus infection, Kumamoto University, Department of Immunology,
Faculty of Medicine, Academic Assembly, University of Toyama, 3)Department of Immunology, Kochi University
WS28-04-O/P	Analysis of SARS-CoV-2 pathogenicity in COVID-19 cynomolgus macaque model reflecting human
COVID-19 pathological conditions〇 Emiko Urano, Tomotaka Okamura, Yasuhiro Yasutomi
Tsukuba Primate Research Center, National Institutes of Biomedical Innovation, Health and Nutrition

WS28-05-O/P

Role of histone ubiquitination in SARS-CoV2 and influenza virus infection〇 Yumiko Imai, Yasuha Kinugasa, Midori Hoshizaki, Mara Llamas Covarrubias
National Institutes of Biomedical Innovation, Health and Nutrition, Center for Vaccine &Adjuvant Research147

WS28-06-O/P

Characterization of airway M cell: a potential contribution to respiratory diseases
1, 2)
1)
1, 3)
1, 3)
4)
1)
〇 Shunsuke Kimura , Shingo Kawai , Takahiro Yamada , Yutaka Nakamura , Shinichiro Sawa , Hase Koji

1)

Division of Biochemistry, Faculty of Pharmacy, Keio University, Tokyo, Japan, 2)PRESTO, Japan Science and Technology Agency, Saitama,
Japan, 3)Department of Microbiology and Immunology, School of Pharmaceutical Sciences, Wakayama Medical University, Wakayama, Japan.,
4)
Division of Mucosal Immunology, Research Center for Systems Immunology, Medical Institute of Bioregulation, Kyushu University
WS28-07-O/P

	Immune Profiling of HTLV-1-Specific CTLs in Peripheral Blood and Cerebrospinal Fluid of HAM/TSP
Patients for Elucidation of Immunoregulatory Mechanisms and Novel Biomarker Discovery〇 Benjy Jek Yang Tan , Kenji Sugata , Tomoo Sato , Mitsuharu Ueda , Yoshihisa Yamano , Yorifumi Satou
1)

1)

2)

3)

2)

1)

1)

2)

Division of Genomics & Transcriptomics, Joint Research Center for Human Retrovirus Infection, Kumamoto University, Department ofRare Diseases Research, School of Medicine, St. Marianna University, Kanagawa, 3)Department of Neurology, Kumamoto University Hospital,
Kumamoto
WS28-08-O/P

Investigation of the role of follicular CD8 T cells for reducing viral reservoirs under cART treatment〇 Ayaka Washizaki , Shokichi Takahama , Tomotaka Okamura , Takuto Nogimori , Yuji Masuta , Yorifumi Satou ,Takuya Yamamoto1, 4, 5)
1)

1)

2)

1)

1)

3)

1)

Laboratory of Immunosenescence, National Institutes of Biomedical Innovation, Health and Nutrition, Osaka, Japan, 2)Tsukuba primate research
center, National Institutes of Biomedical Innovation, Health and Nutrition, Ibaraki, Japan, 3)Division of Genomics and Transcriptomics, Joint
Research Center for Human Retrovirus Infection, Kumamoto University, Kumamoto, Japan, 4)Laboratory of Aging and Immune Regulation,
Graduate School of Pharmaceutical Sciences, Osaka University, Osaka, Japan, 5)Department of Virology and Immunology, Graduate School of
Medicine, Osaka University, Osaka, Japan
WS28-09-P

Establishment of anti-TMPRSS2 mAbs that potently inhibit infection of any variants of SARS-CoV-2〇 Michishige Harada , Takehisa Matsumoto , Mizuki Yamamoto , Jin Gohda , Akiko Idei , Kouske Miyauchi ,Mikako Shirouzu1), Jun-Ichiro Inoue2), Takashi Saito1)
1)

1)

2)

2)

3)

1)

1)

1-7-22 Suehiro-cho, Tsurumi-ku, Yokohama City, Kanagawa, 230-0045, Japan, 2)4-6-1 Shirokanedai, Minato-ku, Totkyo, 108-8639, Japan,
2-1 Hirosawa, Wako, Saitama 351-0198, Japan3)

WS28-10-P	Induction of antibodies which cross-neutralize various SARS-CoV-2 variants in COVID-19 convalescentpatients〇 Takeo Kuwata, Yu Kaku, Kikiko Shimizu, Shashwata Biswas, Kaho Matsumoto, Shuzo Matsushita
Joint research Center for Human retrovirus Infection, Kumamoto University, Kumamoto, Japan

WS28-11-P

SARS-CoV-2 vaccination robustly increases memory B cells while persistently maintains memory T cells〇 Akihiko Yoshimura, Setsuko Mise-Omata, Mari Ikeda
Department of Microbiology and Immunology, Keio University School of Medicine

WS28-12-P

	In-depth analysis of SARS-CoV-2-specific CD8+ T cells of moderate/severe COVID-19 convalescents using
single cell RNA-sequencing analysis〇 Hideki Ogura , Jin Gohda , Xiuyuan Lu , Mizuki Yamamoto , Hiromoto Murakami , Kunihiro Shirai ,Sho Yamasaki3), Jun-Ichi Hirata4), Satoshi Ishido1)
1)

2)

3)

2)

4)

4)

1)

Department of Microbiology, Hyogo Medical University, Hyogo, Japan, 2)Research Center for Asian Infectious Diseases, The Institute ofMedical Science, The University of Tokyo, Tokyo, Japan, 3)Department of Molecular Immunology, Research Institute for Microbial Diseases,
Osaka University, Suita, Japan, 4)Department of Emergency and Critical Care Medicine, Hyogo Medical University, Hyogo, Japan

WS28-13-P

Establishment of a mouse model for SARS-CoV-2 virus infection and analysis of itsaftereffects〇 Hitomi Watanabe , Kazuko Miyazaki , Toru Okamoto , Gen Kondoh , Masaki Miyazaki
1)

1)

2)

1)

1)

1)

2)

Kyoto University, Institute for Life and Medical Sciences, laboratory of integrative biological sciences, Institute for Advanced Co-Creation
Studies Research Institute for Microbial Diseases Osaka University
WS28-14-P

	FOXO1 inhibitor has the anti-viral and anti-inflammatory effects against SARS-CoV-2 infection in a Syrian
hamster model〇 Ryutaro Furukawa, Noriko Ouji Sageshima, Masahiro Kitabatake, Toshihiro Ito
Department of Immunology, Nara Medical University, Nara, Japan148

WS28-15-P

Elucidation of SARS-CoV2 entry mechanism by using human functional monoclonal antibodies
1)
1)
2, 3)
4)
5)
2, 3)
〇 Ryota Otsubo , Takeharu Minamitani , Kouji Kobiyama , Shiori Ueno , Ken-Ichi Imadome , Ken Ishii ,6, 7, 8)4)
1)Kouhei Tsumoto, Wataru Kamitani , Teruhito Yasui
1)

Laboratory of Infectious Diseases and Immunity, Center for Vaccine and Adjuvant Research(CVAR), National Institutes of Biomedical
Innovation, Health and Nutrition (NIBIOHN), Osaka, Japan, 2)Division of Vaccine Science, Department of Microbiology and Immunology, The
Institute of Medical Science, The University of Tokyo, Tokyo, Japan, 3)Laboratory of Adjuvant Innovation, CVAR, NIBIOHN, Osaka, Japan,
4)
Department of Infectious diseases and Host Defense, Graduate School of Medicine, Gunma University, Gunma, Japan, 5)Department ofAdvanced Medicine for infections, National Center for Child Health and Development (NCCHD), Tokyo, Japan, 6)Center for Drug Discovery
Research (CDDR), NIBIOHN, Oasaka, Japan, 7)Department of Bioengineering, School of Engineering, The University of Tokyo, Tokyo, Japan,
8)
Medical Proteomics Laboratory, The Institute of Medical Science, The University of Tokyo, Tokyo, Japan
WS28-16-P

	Improved immunogenicity of the recombinant vaccinia virus by targeting the immunomodulatory A46R
gene locus
1)
1)
1)
1)
1, 2)
〇 Akihiko Sakamoto , Hinata Hashimoto , Hiroaki Osawa , Saya Yamauchi , Tetsushi Mizuno ,Kyouhei Yamagata1), Keigo Mitsuhashi1), Jingru Che1), Ryohei Ogawa3), Mitsuhiro Iyori1, 4), Hisatoshi Shida5),
Shigeto Yoshida1)
1)

Kanazawa University School of Pharmacy, Kanazawa, Ishikawa, Japan, 2)Graduate School of Medical Sciences, Kanazawa University, Kanazawa,
Ishikawa, Japan, 3)Faculty of Medicine, Academic Assembly, University of Toyama, Toyama, Toyama, Japan, 4)Department of Pharmaceutical
Sciences, Musashino University, Tokyo, Japan, 5)Institute for Genetic Medicine, Hokkaido University, Sapporo, Japan
WS28-17-P

Combination of protein and DNA vaccine enhanced T-cell-mediated immune responses〇 Shih-Jen Liu

1, 2, 3)

, Hung-Chun Liao1, 4)

1)National Institute of Infectious Diseases and Vaccinology, National Health Research Institutes, Miaoli, Taiwan, 2)Graduate Institute of Biomedical
Sciences, China Medical University, Taichung, Taiwan, 3)Graduate Institute of Medicine, College of Medicine, Kaohsiung Medical University,
Kaohsiung, Taiwan, 4)Department of Life Sciences, National Tsing Hua University, Hsinchu, Taiwan
WS28-18-P

Concomitant cytotoxic effector differentiation of CD4+ and CD8+ T cells in response to EBV infected B cells〇 Yumi Tamura, Keita Yamane, Moeka Mori, Yohei Kawano, Shun Ohki, Yasuo Kitajima, Tomoharu Yasuda
Department of Immunology, Graduate School of Biomedical and Health Sciences, Hiroshima University, Hiroshima, Japan

WS28-19-P

Enhanced detection of virus-specific CD8+ T cells by XCL1 chemokine〇 Yuta Kimura , Takuto Nogimori , Ayaka Washizaki , Takuya Yamamoto
1)

2)

2)

1)

2, 3, 4)

, Yasuko Tsunetsugu-Yokota1, 2, 5)

2)Graduate School of Medical Technology, Tokyo University of Techology, Tokyo, Japan, Laboratory of Immunosenescence, Center for Vaccine
and Adjuvant Research, National Institutes of Biomedical Innovation, Health and Nutrition, Osaka, Japan, 3)Laboratory of Aging and Immune
Regulation, Graduate School of Pharmaceutical Sciences, Osaka University, Osaka, Japan, 4)Department of Virology, Research Institute forMicrobial Diseases, Osaka University, Osaka, Japan, 5)Department of Medical Technology, School of Human Sciences, Tokyo University ofTechnology, Tokyo, Japan
WS28-20-P

	Autologous PBMC vaccination in STLV-1-infected Japanese macaques as a preclinical model for a novel
immunotherapy for adult T-cell leukemia/lymphoma
1, 2)
1, 3)
4)
〇 Atsuhiko Hasegawa , Mari Kannagi , Hirofumi Akari

1)
Department of Immunotherapeutics, Tokyo Medical & Dental University, Tokyo, Japan, 2)Institute for Clinical Research, National Hospital
Organization Kyushu Cancer Center, Fukuoka, Japan, 3)Department of Microbiology, Kansai Medical University, Osaka, Japan, 4)Center for
Human Evolution Modeling Research, Primate Research Institute, Kyoto University, Kyoto, Japan

WS28-21-P

Immune response to endogenous retroviruses〇 Kagefumi Todo , Masaki Hikida
1)

2)

1)

Department of Health and Nutrition, Tokiwa University, 2)Graduate School of Engineering Science, Akita University

WS28-22-P

Spermidine enhanced the cellular and humoral immune response by cyclic GMP-AMP in HBsAg vaccination〇 Hiroyasu Ito , Daisuke Ito , Masahito Shimizu
1)

2)

2)

1)

Department of Joint Research Laboratory of Clinical Medicine, Fujita Health University School of Medicine, 2)Department of Gastroenterology,
Gifu University Graduate School of Medicine
WS28-23-P

Identification of integrins as a receptor for chronic encephalomyelitis virus〇 Kazuya Takeda, Tomonori Kaifu, Akira Nakamura
Division of Immunology, Faculty of Medicine, Tohoku Medical and Pharmaceutical University, Sendai, Japan149

A novel drug targeting approach: Inhibition of Plasmodium parasite life cycle

WS28-24-P

1, 2)
1, 3)
3, 4)
3, 4)
3, 4, 5), Cevayir Coban1, 2, 3, 4)〇 Rashmi Dash , Michelle Sj Lee , Hideo Negishi , Ken. J. Ishii , Shiroh Iwanaga

1)Division of Malaria Immunology, Institute of Medical Science (IMSUT), University of Tokyo, 2)Graduate School of Frontier Science, The
University of Tokyo, 3)Division of Vaccine science, IMSUT, 4)International Vaccine Design Center, IMSUT, 5)Department of Protozoology, RIMD,
Osaka University

Application of Compact Immunoassay System to On-Site COVID Antibody Testing

WS28-25-P〇 Akihiro Shirai, Kazuyo Yoshida, Koki Hoshikawa, Shun Nakamoto, Yuki Akasaka, Shunsuke Hazama,
Kazuyoshi Horii
Sysmex Corporation, Kobe, Japan

December 9
WS29

Dendritic cells and macrophages-3: Regulation of cytokine production, pathogenesis

WS29-01-O/P

Regulatory Mechanism in Innate Immune Response by a CCCH-type Zinc Finger Protein, ENZ-1〇 Norisuke Kano, Daisuke Ori, Takumi Kawasaki, Taro Kawai
Division of Science and Technology, Laboratory of Molecular Immunobiology, Nara Institute of Science and Technology, Nara, Japan

WS29-02-O/P

Regulation of Il6 Expression by a Single CpG methylation in the Il6 locus〇 Takumi Kawasaki, Benedict Shi Xiang Lian, Daisuke Ori, Taro Kawai
Nara Institute of Science and Technology (NAIST), Laboratory of Molecular Immunobiology

WS29-03-P

Positive effects on selective autophagy by quercetin-induced heme oxygenase-1〇 Hinata Taniguchi , Miyoko Matsushima , Sayaka Takagi , Moeko Ohara , Hikaru Tsuzuki , Nodoka Shimasaki ,Ayumi Tajima1), Hina Kawashima2), Fuzuki Hayashi2), Nanami Yoshida2), Tsutomu Kawabe1)
1)

1)

2)

1)

1)

1)

1)
Department of Integrated Health Sciences, Nagoya University Graduate School of Medicine, Aichi, Japan, 2)Department of Medical Technology,
Nagoya University School of Health Sciences, Aichi, Japan

WS29-04-P

Synergistic effects of Toll-like receptor signaling on inflammation induced by silica nanoparticles〇 Nanami Yoshida , Miyoko Matsushima , Moeko Ohara , Hikaru Tsuzuki , Nodoka Shimasaki , Ayumi Tajima ,Hinata Taniguchi2), Hina Kawashima1), Sayaka Takagi1), Fuzuki Hayashi1), Tsutomu Kawabe2)
1)

2)

2)

2)

2)

2)

1)
Department of Medical Technology, Nagoya University School of Health Sciences, Aichi, Japan, 2)Department of Integrated Health Sciences,
Nagoya University Graduate School of Medicine, Aichi, Japan

WS29-05-O/P

	O6-alkylguanine DNA alkyltransferase (MGMT) Regulates Beta-Glucan-induced Trained Immunity inMacrophages
1, 2, 3), Salisa Benjaskulluecha1, 2), Atsadang Boonmee3), Thitiporn Pattarakankul3, 4),〇 Tanapat Palaga
3)
Benjawan Wongprom
1)
Center of Excellence in Immunology and Immune-Mediated Diseases, Chulalongkorn University, Bangkok, Thailand, 2)Interdisciplinary
Graduate Program in Medical Microbiology, Graduate School, Chulalongkorn University, Bangkok, Thailand, 3)Department of Microbiology,
Faculty of Science, Chulalongkorn University, Bangkok, Thailand, 4)Center of Excellence in Advanced Materials and Biointerfaces, Chulalongkorn
University, Bangkok, Thailand

WS29-06-O/P

	Novel function of clathrin heavy chain regulating NLRP3 inflammasome formation via endocytosis inmacrophages〇 Hiep Hung Huynh , Eri Koike , Masumi Shimizu , Rimpei Morita , Akihiko Yoshimura
1)

1)

1)

1)

1)

2)

2)

Nippon Medical School, Tokyo, Japan, Keio University School of Medicine, Tokyo, Japan

WS29-07-P	Sphingosine-1-phosphate lyase promotes inflammasome activation via the development of endoplasmic
reticulum network〇 Fumiyuki Sasaki, Masumi Shimizu, Rimpei Morita
Department of Microbiology and Immunology, Nippon Medical School, Tokyo, Japan

WS29-08-P

Gelsolin-actin axis organizes NLRP3 inflammasome activation〇 Masumi Shimizu , Jiyeon Lee , Fumiyuki Sasaki , Akihiko Yoshimura , Lark Kyun Kim , Rimpei Morita
1)

2)

1)

1)

3)

2)

2)

1)

Department of Microbiology and Immunology, Nippon Medical School, Tokyo, Japan, Severance Biomedical Science Institute, Yonsei
University School of Medicine, 3)Department of Microbiology and Immunology, Keio University School of Medicine, Tokyo, Japan150

WS29-09-P

	Caspase-11 triggers NLRP3 inflammasome activation in macrophages infected with Acinetobacterbaumannii〇 Yasuyuki Matsuda, Kenichiro Mori, Hideki Hara
Department of Microbiology and Immunochemistry, Asahikawa Medical University, Asahikawa, Japan

WS29-10-O/P

	Dendritic and T cell abnormalities in an autoinflammatory disease with interstitial lung disease and type
I interferonopathy caused by a disability of retrograde protein trafficking
1)
1)
1, 2)
3, 4, 5)
, Kazushi Izawa5), Ryuta Nishikomori6),〇 Takashi Kato , Izumi Sasaki , Hiroaki Hemmi , Yoshitaka Honda
1)
Tsuneyasu Kaisho
1)

Department of Immunology, Institute of Advanced Medicine, Wakayama Medical University, Wakayama, Japan, 2)Laboratory of Immunology,
Faculty of Veterinary Medicine, Okayama University of Science, Imabari, Japan, 3)Institute for the Advanced Study of Human Biology (ASHBi),
Kyoto University, Kyoto, Japan, 4)Department of Immunology, Kyoto University Graduate School of Medicine, Kyoto Japan, 5)Department ofPediatrics, Kyoto University Graduate School of Medicine, Kyoto Japan, 6)Department of Pediatrics and Child Health, Kurume University Schoolof Medicine, Kurume, Japan
WS29-11-O/P

The role of RNase T2 in macrophage homeostasis〇 Ryota Sato , Kaiwen Liu , Takuma Shibata , Ryutaro Fukui , Katsuaki Hoshino , Tsuneyasu Kaisho ,Kensuke Miyake1)
1)

1)

1)

1)

2)

3)

1)

Division of Innate Immunity, The Institute of Medical Science, The University of Tokyo, Tokyo, Japan., 2)Department of Immunology, Facultyof Medicine, Kagawa University, Kagawa, Japan., 3)Department of Immunology, Institute of Advanced Medicine, Wakayama Medical University,
Wakayama, Japan
WS29-12-P	Differential pathogenesis of non-alcoholic steatohepatitis in type 2 diabetic TSOD mice and their control
TSNO mice〇 Naoya Igarashi
Department of Pharmaceutical Engineering, Faculty of Engineering, Toyama Prefectural University

WS29-13-P	Analysis of liver macrophage subsets in a novel dietary mouse model of non-alcoholic steatohepatitis,“3-F mice”〇 Yuki Tada , Kaichi Kasai , Nana Makiuchi , Koichi Tsuneyama , Yoshinori Nagai
1)

1)

1)

2)

1)

1)

Department of Pharmaceutical Engineering, Faculty of Engineering, Toyama Prefectural University, Toyama, Japan, 2)Department of Pathology
and Laboratory Medicine, Tokushima University Graduate School, Tokushima, Japan
WS29-14-O/P	FROUNT inhibitor disulfiram ameliorates crescentic glomerulonephritis through the inhibition of
monocytes/macrophage migration and activation
1, 2)
1)
1)
1)
1)
1)
〇 Etsuko Toda , Anri Sawada , Kazuhiro Takeuchi , Mika Terasaki , Shinobu Kunugi , Yasuhiro Terasaki ,2)
2)
1)
Kouji Matsushima , Yuya Terashima , Akira Shimizu
1)
Department of Analytic Human Pathology, Nippon Medical School, Tokyo, Japan, 2)Division of Molecular Regulation of Inﬂammatory and
Immune Diseases, Research Institute for Biomedical Sciences, Tokyo University of Science, Chiba, Japan

WS29-15-O/P

The leukotriene B4-BLT1 axis in neutrophils exacerbates crescentic glomerulonephritis

1, 2)
1, 3)
1, 4)
1)
1, 2)
〇 Masatsugu Oh-Hora , Ryotaro Shioda , Airi Jo-Watanabe , Toshiaki Okuno , Kazuko Saeki ,3)3)1)
Maiko Nakayama , Yusuke Suzuki , Takehiko Yokomizo
1)
Department of Biochemistry, Juntendo University Graduate School of Medicine, 2)Laboratory of Molecular Immunology, Immunology Frontier
Research Center, Osaka University, 3)Department of Nephrology, Juntendo University Faculty of Medicine, 4)AMED-PRIME, Japan Agency for
Medical Research and Development

WS29-16-P

	JAK inhibition ameliorates bone destruction by simultaneously targeting mature osteoclasts and theirprecursors〇 Yari Shinya, Kikuta Junichi, Masaru Ishii
Department of Immunology and Cell Biology, Graduate School of Medicine and Frontier Biosciences, Osaka University, Osaka, Japan

WS29-17-P	Analysis of the mechanism of heterotopic ossification and immune response in fibrodysplasia ossificans
progressiva (FOP)
1, 2)
3)
2)
4)
3)
〇 Asuka Terashima , Wenqiang Yin , Kazuo Okamoto , Takehito Ono , Hiroshi Takayanagi

1)Bone and Cartilage Regenerative Medicine, The University of Tokyo Hospital, 2)Department of Osteoimmunology, Graduate School of Medicine
and Faculty of Medicine, The University of Tokyo, 3)Department of Immunology, Graduate School of Medicine and Faculty of Medicine, The
University of Tokyo, 4)Department of Cell Signaling, Graduate School of Medical and Dental Sciences, Tokyo Medical and Dental University

151

MAFB in macrphage is important in the recovery of AKI

WS29-18-P

1, 2)
2)
1, 2)
2, 3)
2, 3)
2)
〇 Maho Kanai , Teppei Nishino , Akari Kimura , Toshiaki Usui , Naoki Morito , Michito Hamada ,2)Satoru Takahashi
1)Ph.D. Program in Human Biology, University of Tsukuba, 2)Laboratory of Anatomy and Embryology, University of Tsukuba, 3)Department ofNephrology, Faculty of Medicine, University of Tsukuba

WS29-19-P

	Sustained reduction of alveolar macrophages predisposes the post-intensive care syndrome after
successful treatment of severe peritonitis in mice
〇 Azusa Kato , Hiroyuki Nakashima , Kazuma Mori , Keiko Tanoue , Hiroyasu Goto , Kazuki Koiwai ,Masahiro Nakashima1), Manabu Kinoshita1)
1)

1)

1)

2)

2)

1)

1)
Department of Immunology and Microbiology, National Defense Medical College, Saitama, Japan, 2)Department of Nephrology and
Endocrinology, National Defense Medical College, Saitama, Japan

Changes in the fetal membrane due to Subchorionic hematoma

WS29-20-P〇 Eriko Yasuda, Haruta Mogami, Yu Matsuzaka, Asako Inohaya, Masahito Takakura, Yusuke Ueda, Yosuke Kawamura,
Yoshitsugu Chigusa, Masaki Mandai
Department of Gynecology and Obstetrics, Kyoto University Graduate School of Medicine, Kyoto, Japan
WS29-21-P	Increased IDO, CD38 and LDH expression in lung macrophages and endothelial cells indicating NAD+dysmetabolism in cynomolgus macaques infected with SARS-CoV-2〇 Cong Thanh Nguyen, Hinata Soh, Misako Nakayama, Hirohito Ishigaki, Yasushi Itoh
Division of Pathogenesis and Disease Regulation, Department of Pathology, Shiga University of Medical Science, Shiga, Japan

Repetitive reduction of granulocytes and monocytes ameliorates pulmonary arterial hypertension

WS29-22-P〇 Yujin Nishioka , Daichi Takemasa , Goh Murayama , Makio Kusaoi , Taiga Kuga , Takumi Saito ,Yukitomo Hagiwara1), Kenta Kaneda2), Ken Yamaji1), Naoto Tamura1)
1)

2)

1)

1)

1)

1)

1)

Department of Internal Medicine and Rheumatology, Juntendo University School of Medicine, 2)JIMRO Co.,Ltd.

Immunomodulatory effects of D-allose on the function of plasmacytoid dendritic cells

WS29-23-P

1, 2)
1, 3)
1)
3)
2)
〇 Katsuaki Hoshino , Kenjiro Takao , Makiko Suzuki , Minoru Miyake , Kazuya Akimitsu

1)
Department of Immunology, Faculty of Medicine, Kagawa University, Miki, Kagawa, Japan, 2)International Institute of Rare Sugar Research and
Education, Kagawa University, Miki, Kagawa, Japan, 3)Department of Oral and Maxillofacial Surgery, Faculty of Medicine, Kagawa University,
Miki, Kagawa, Japan

WS29-24-P

	Leukotriene B4 receptor 1 defines functionally and epigenetically distinct DCs that control allergic skininflammation
1, 2)
2)
2)
3)
2)
3)
〇 Tomoaki Koga , Fumiyuki Sasaki , Kazuko Saeki , Soken Tsuchiya , Toshiaki Okuno , Yukihiko Sugimoto ,2)
1)
Takehiko Yokomizo , Mitsuyoshi Nakao
1)

Department of Medical Cell Biology, Institute of Molecular Embryology and Genetics, Kumamoto University, 2)Department of Biochemistry, Juntendo
Graudate School of Medicine, 3)Department of Pharmaceutical Biochemistry, Graduate School of Pharmaceutical Sciences, Kumamoto University

December 9
WS30

Innate immunity (2) Innate recognition and signaling

WS30-01-P

Natural killer T-like cell activity interferes with the pathogenesis of alcohol-induced murine osteoporosis〇 Munehiro Naruo

1, 2, 3)

, Yasuyuki Negishi1), Takahisa Okuda4), Ken Okazaki2), Rimpei Morita1)

1)

Department of Microbiology and Immunology, Nippon Medical School, Tokyo, Japan, 2)Department of Orthopaedic Surgery, Tokyo Women's
Medical University, Tokyo, Japan, 3)Department of Orthopaedic Surgery, Tomei Atsugi Hospital, Kanagawa, Japan, 4)Department of Legal
Medicine, Nihon University School of Medicine, Tokyo, Japan
WS30-02-P

Analysis on the functional role of TXP in antigen cross-presentation〇 Moe Ikegawa, Takumi Kawasaki, Taro Kawai
Laboratory of Molecular Immunobiology, Graduate School of Science and Technology, Nara Institute of Science and Technology, Ikoma Nara, Japan152

WS30-03-O/P	Activation of MyD88- and TRIF-mediated Signaling Pathways by Alcaligenes Lipid A for Efficient Antigen
Presentation and T Cell Differentiation by Dendritic Cells
1, 2)
1)
2)
1, 2)
1, 2)
2)
2)
〇 Xiao Sun , Koji Hosomi , Atsushi Shimoyama , Ken Yoshii , Zilai Liu , Haruki Yamaura , Davie Kenneth ,1)
1, 3)
4, 5, 6)2)
1, 2, 4, 7, 8)Azusa Saika , Takahiro Nagatake , Hiroshi Kiyono, Koichi Fukase , Jun Kunisawa
1)

National Institutes of Biomedical Innovation, Health and Nutrition, Osaka, Japan, 2)Osaka University, Osaka, Japan, 3)Meiji University, Tokyo,
Japan, 4)The University of Tokyo, Tokyo, Japan, 5)University of California San Diego (UCSD), San Diego, CA, United States, 6)Chiba University,
Chiba, Japan, 7)Kobe University, Kobe, Japan, 8)Waseda University, Tokyo, Japan

WS30-04-P

Molecular mechanism of ANGPTL6 recognition by immune activation receptor LILRA2
1)
1, 2)
1)
3, 4)
5)
5)
〇 Jiaqi Wang , Atsushi Furukawa , Rika Yamazaki , Kouyuki Hirayasu , Tsuyoshi Kadomatsu , Yuichi Oike ,Hisashi Arase3), Katsumi Maenaka1)
1)

Faculty of Pharmaceutical Sciences, Hokkaido University, Sapporo, Japan, 2)Faculty of Pharmaceutical Sciences, Kanazawa University,
Kanazawa, Japan, 3)Research Institute for Microbial Diseases, Osaka University, Osaka, Japan, 4)Advanced Preventive Medical Sciences ResearchCenter, Kanazawa University, Kanazawa, Japan, 5)Department of Molecular Genetics, Kumamoto University, Kumamoto, Japan

WS30-05-O/P

Roles of the innate immune receptor RP105 in the development of nonalcoholic steatohepatitis〇 Shun Takano
Department of Pharmaceutical Engineering, Faculty of Engineering, Toyama Prefectural University

WS30-06-P

	The Bruton’s tyrosine kinase (Btk) inhibitor acalabrutinib suppress LPS-induced sepsis via inhibition of
marginal zone B cells activation〇 Shinya Hatano, Kazuhiko Kawata, Yoshihiro Baba
Division of Immunology and Genome Biology, Medical Institute of Bioregulation, Kyushu University, Fukuoka, Japan

WS30-07-O/P	NOP16, a novel epigenetic modifier, suppresses the excessive innate inflammatory response by
regulating cellular stress〇 Ken Takashima, Yohana Mtali, Hiroyuki Oshiumi
Department of Immunology, Faculty of Life Sciences, Kumamoto University, Kumamoto, Japan

WS30-08-O/P

A lethal cross-talk between innate immune and adrenergic receptor signaling〇 Shuto Tanaka, Masataka Kawakita, Kazuhiko Takahara
Laboratory of Immunobiology, Graduate School of Biostudies, Kyoto University, Kyoto, Japan

WS30-09-P

	The rapid phagocytic activation via AnnexinA2-Galectin-3-F-actin signaling axis in serum-MAF treatedmacrophages〇 Kumpei Kawakatsu, Yoshika Seta, Takahito Nishikata
Frontiers of Innovative Research in Science and Technology (FIRST), Konan University

WS30-10-P

	An Aicardi–Goutières syndrome-causative point mutation in Adar1 gene invokes multi-organ
inflammation and late-onset encephalopathy in mice
〇 Taisuke Nakahama, Yukio Kawahara
Department of RNA Biology and Neuroscience, Graduate School of Medicine, Osaka University

WS30-11-P

Protein-protein interaction of RNA binding proteins induced by anti-viral response
1)
2)
2, 3)
1, 4)
1, 4)
〇 Yoshimasa Asano , Koji Onomoto , Mitsutoshi Yoneyama , Yuta Otobe , Hikari Yoshitane
1)

Department of Biological Sciences, Graduate School of Science, The University of Tokyo, 2)Division of Molecular Immunology, Medical
Mycology Research Center, Chiba University, 3)Research Institute of Disaster Medicine, Chiba University, 4)Tokyo Metropolitan Institute ofMedical Science
WS30-12-P

NOD1 suppresses ER stress-induced inflammation via IRE1/ASK1/MAPK pathway
1, 2)
2, 3)
2)
4)
1)
2)
〇 Yoshitaka Kimura , Miyako Yamanaka , Daisuke Tsukui , Noriko Miura , Yusuke Yoshino , Hajime Kono

1)

Department of Microbiology and Immunology, Teikyo University School of Medicine, Tokyo, Japan, 2)Department of Internal Medicine, Teikyo
University of Medicine, Tokyo, Japan, 3)Division of Regenerative Therapy, Juntendo University Graduate School of Medicine, Tokyo, Japan,
4)
School of Pharmacy, Tokyo University of Pharmacy and Life Sciences, Tokyo, Japan
WS30-13-O/P	Glucagon-like Peptide-1 Receptor Agonist ameliorates inflammatory myopathies via suppressing muscle
fiber necroptosis〇 Mari Kamiya, Marina Tsuchida, Hirokazu Sasaki, Natsuka Umezawa, Shinsuke Yasuda
Department of Rheumatology, Graduate School of Medical and Dental Sciences, Tokyo Medical and Dental University (TMDU)

153

Nanaomycin E inhibits NLRP3 inflammasome activation by preventing mitochondrial dysfunction

WS30-14-P〇 Naoki Takemura, Tatsuya Saitoh
Laboratory of Bioresponse Regulation, School of Pharmaceutical Sciences, Osaka University, Osaka, Japan

Type I IFN-inducing cell death by low molecular compounds

WS30-15-P〇 Hideo Negishi , Yusuke Wada , Yoshitaka Shirasaki , Ken Ishii
1)

1)

2)

1)

1)

Division of Vaccine Science, the Institute of Medical Science, University of Tokyo, Tokyo, Japan., 2)Graduate School of Pharmaceutical
Sciences, The University of Tokyo, Tokyo, Japan
WS30-16-O/P

	Kinetics of signaling via common Fc receptor γ (FcRγ) chain determine dendritic cell responses byaltering chromatin status〇 Miyuki Watanabe

1, 2, 3)

, Sho Yamasaki1, 2, 4)

1)

Department of Molecular Immunology, Research Institute for Microbial Diseases, Osaka University, Osaka, Japan, 2)Laboratory of Molecular
Immunology, Immunology Frontier Research Center, Osaka University, Osaka, Japan, 3)Division of Mucosal Immunology, Research Center for
Systems Immunology, Medical Institute of Bioregulation, Kyushu University, Fukuoka, Japan, 4)Center for Infectious Disease Education andResearch (CiDER), Osaka University, Osaka, Japan
WS30-17-P	Roles of an innate immune receptor RP105 in the disruption of intestinal barrier function associated withmetabolic syndrome〇 Koudai Kani, Shun Takano, Riko Ishibashi, Yukihiro Furusawa, Yoshinori Nagai
Department of Pharmaceutical Engineering, Faculty of Engineering, Toyama Prefectural University, Toyama, Japan

Sa15-21 mAb induces activation signal through TLR4/MD-2 in the Liver

WS30-18-P〇 Mrityunjoy Biswas, Masanori Inui, Tatsuya Yamazaki, Susumu Tomono, Sajid Iftekhar Chowdhury,
Sachiko Akashi-Takamura
Aichi Medical University School of Medicine, Nagakute, Aichi, JapanThe Ragulator complex regulates NLRP3 inflammasome activation through interaction with HDAC6

WS30-19-O/P〇 Kohei Tsujimoto, Tatsunori Jo, Hyota Takamatsu, Atsushi Kumanogoh
Department of Respiratory Medicine and Clinical Immunology, Graduate School of Medicine, Osaka University

TLR7 stress response drives histiocytosis in SLC29A3 disorders

WS30-20-P〇 Takuma Shibata, Ryota Sato, Shin-Ichiroh Saitoh, Kensuke Miyake
Division of Innate Immunity, Department of Microbiology and Immunology, The Institute of Medical Science, The University of Tokyo, Tokyo, Japan.

December 9
WS31

Autoimmunity

WS31-01-O/P

Moesin deficiency leads to the local CXCL13 expression and inflammation in the kidney〇 Satoko Ichioka, Hiroki Satooka, Takako Hirata
Department of Fundamental Biosciences, Shiga University of Medical Science

WS31-02-O/P

Neutrophils exacerbate the pathogenesis of pulmonary fibrosis by cleaving IL-33
1)
1, 2)
1, 2)
〇 Yuki Hara , Yasutaka Motomura , Kazuyo Moro
1)

Laboratory for Innate Immune Systems, Department of Microbiology and Immunology, Graduate School of Medicine, Osaka University, Osaka,
Japan, 2)Laboratory for Innate Immune Systems, RIKEN IMS, Kanagawa, Japan
WS31-03-O/P

	Tissue-specific deficiency of clonally expanded regulatory T cells underlies tissue-restricted inflammationin Foxp3A384T mutant mice
〇 Yoshimichi Hoshiya
Laboratory of Immunology and Microbiology, Graduate School of Pharmaceutical Sciences, The University of Tokyo, Tokyo, Japan

WS31-04-O/P

Treatment for autoimmune diseases with engineered exosome
1)
2, 3)
2)
2, 3)
〇 Shota Imai , Tomoyoshi Yamano , Xiabing Lyu , Rikinari Hanayama
1)

Department of immunology, School of Frontier Science initiative division of Nano life science, Kanazawa University, Kanazawa, Japan,
Department of Immunology, Graduate School of Medical Sciences, Kanazawa University, Kanazawa, Japan, 3)WPI Nano Life Science Institute(NanoLSI), Kanazawa University, Kanazawa, Japan2)

154

WS31-05-O/P

A new transcriptional mechanism of ectopic MHC class II expression induced by IFN-γ
1, 2)
1, 2)
1, 2)
1, 2)
〇 Wataru Nakai , Yuta Shimizu , Masako Kohyama , Hisashi Arase1)
Department of Immunochemistry, Research Institute for Microbial Diseases, Osaka University, 2)Laboratory of Immunochemistry, WPI
Immunology Frontier Research Center, Osaka University

WS31-06-O/P

	Autoantibodies to the Survival of Motor Neuron (SMN) complex as a novel marker for pulmonary arterial
hypertension in patients with mixed connective tissue disease (MCTD)
1)
2, 3)
1)
1)
2)
1)
〇 Yasuyuki Todoroki , Minoru Satoh , Satoshi Kubo , Shumpei Kosaka , Shin Tanaka , Shingo Nakayamada ,1)
Yoshiya Tanaka
1)

First Department of Internal Medicine, University of Occupational and Environmental Health, Japan, 2)Department of Human, Information andLife Sciences, University of Occupational and Environmental Health, Japan, 3)Kitakyushu Yahata Higashi Hospital
WS31-07-O/P

RNase-induced Fc gamma receptor stimulation of Ro60/SSA- and La/SSB- immune complexes〇 Ryota Naito
Hisashi Arase2, 3)

1, 2, 3)

, Koichiro Ohmura1), Shuhei Higuchi2, 3), Wataru Nakai2, 3), Masako Kohyama2, 3), Akio Morinobu1),

1)
Department of Rheumatology and Clinical Immunology, Graduate School of Medicine, Kyoto University, Kyoto, Japan, 2)World PremierInternational Immunology Frontier Research Center, Osaka University, Suita, Japan, 3) Research Institute for Microbial Diseases, Osaka
University, Suita, Japan

WS31-08-O/P

HLA analysis of the Nivolumab-induced ACTH deficiency〇 Keiko Udaka , Mitsuru Nishiyama , Shogo Funakoshi , Takashi Shiina , Takeyuki Shimizu , Toshihiro Komatsu ,Hiroshi Hamana4), Hiroyuki Kishi4), Kousuke Onoue5), Yuki Tanaka5), Tetsu Aihara6), Youki Nakagawa6)
1)

2)

2)

3)

1)

1)

1)

Department of Immunology, School of Medicine, Kochi University, Nankoku, Japan, 2)Department of Endocrinology, Metabolism andNephrology, School of Medicine, Kochi University, Nankoku, Japan, 3)Division of Basic Medical Science and Molecular Medicine, Departmentof Molecular Life Science, Tokai University, Isehara, Japan, 4)Department of Immunology, Faculty of Medicine, Academic Assembly, Universityof Toyama, Toyama, Japan, 5)AI Drug Development Division, NEC Corporation, Tokyo, Japan, 6)Advanced Science Course, School of Medicine,
Kochi University, Nankoku, Japan
WS31-09-P	Identification of susceptibility genes for ANCA-associated vasculitis in SCG/Kj mice by the establishmentof congenic mice and the RNA-sequence〇 Yoshitomo Hamano , Shuji Matsuoka , Akihito Nagahara , Ko Okumura , Hideo Yagita , Fuyu Ito , Takumi
Kobayashi3), Kazuho Ikeo3), Wako Yumura4), Naoki Maruyama4), Kazuo Suzuki5)
1)

1)

1)

1)

1)

2)

1)

Department of Immunological Diagnosis, Juntendo University Graduate School of Medicine, 2)Asia International Institute of Infectious Disease
Control, Teikyo University, 3)The National Institute of Genetics, 4)Tokyo Metropolitan Institute of Gerontology, 5)A-CLIP InstituteWS31-10-P

	Th2 response enhances the differentiation into follicular B cells to progress the pulmonary autoimmune
lesions in a mouse model of Sjögren’s syndrome〇 Mami Sato, Aya Ushio, Kunihiro Otsuka, Takaaki Tsunematsu, Naozumi Ishimaru
Department of Oral Molecular Pathology, Tokushima University Graduate School of Biomedical Sciences, Tokushima, Japan

WS31-11-P	Universal LCMS-based assay platform, refmAb-Q nSMOL, for monitoring monoclonal antibody
therapeutics using Fab-selective proteolysis〇 Takashi Shimada , Noriko Iwamoto , Yoshinobu Koguchi , Kotoko Yokoyama , Akinobu Hamada ,Atsushi Yonezawa4), Brian Piening2), Eric Tran2), Bernard Fox2), William Redmond2)
1)

1)

2)

1)

3)

1)

Technology Research Laboratory, Shimadzu Corporation, Kyoto, Japan, 2)Earle A. Chiles Research Institute, Providence Cancer Institute,
Portland, Oregon, 3)Division of Molecular Pharmacology, National Cancer Center Research Institute, Tokyo, Japan, 4)Clinical Pharmacology andTherapeutics, Kyoto University Hospital, Kyoto, Japan
WS31-12-P

Computer model of foam cell formation in atherosclerosis〇 Satoshi Yamada , Akihiko Yoshimura , Masaaki Murakami
1)

2)

3, 4)

1)

Depeartment of Information Science and Engineering, Okayama University of Science, Okayama, Japan, 2)School of Medicine, University of
Keio, Tokyo, Japan, 3)Institute for Genetic Medicine, Hokkaido University, Sapporo, Japan, 4)Institute for quantum life science, National institutes
for quantum and radiological science and technology, Chiba, Japan
WS31-13-P

	The importance of RIG-I like signaling and IFN pathway were suggested in the pathogenesis of antimelanoma differentiation-associated gene 5–positive dermatomyositis (MDA5 DM)〇 Yoshinobu Koyama
Center for autoimmune diseases, division of rheumatology, Japanese Red Cross Okayama Hospital155

WS31-14-P

	Complete Freund’s adjuvant treatment changed the ileal and fecal microbiota differently with alteredimmunoglobulin isotype and anti-tuberculosis antibody responses〇 Sundar Khadka, Seiichi Omura, Fumitaka Sato, Ijaz Ahmad, Ikuo Tsunoda
Department of Microbiology, Kindai University Faculty of Medicine, Osaka, Japan

WS31-15-P

Functional analyses of pathogenic T cells in autoimmune prone mice
〇 Yuriko Tanaka , Akiko Inoue , Taku Naito , Taku Kuwabara , Marii Ise , Terumi Kohwi-Shigematsu ,Motonari Kondo1)
1)

2)

1)

1)

1)

3)

1)
Department of Molecular Immunology, Toho University School of Medicine, 2)Department of Otolaryngology, Toho University School of
Medicine, 3)Department of Orofacial science, University of California San Francisco School of DentistryWS31-16-P

Agonistic anti-PD-1 antibodies downregulate autoantibody development in lupus model mice
1, 2)
1, 2)
1, 2)
1)
3)
3)
〇 Yosuke Tokumaru , Kensuke Suzuki , Iori Ohkura , Masaki Tajima , Satoshi Nagata , Haruhiko Kamada ,Tasuku Honjo1), Akio Ohta1)
1)Foundation for Biomedical Research and Innovation at Kobe, 2)Meiji Seika Pharma Co., Ltd., 3)National Institutes of Biomedical Innovation,
Health and Nutrition
WS31-17-P

Polyclonal Tregs have a therapeutic potency after autoimmune disease onset〇 Yuji Nishimura, Yosuke Nagahata, Hiroshi Kawamoto
Laboratory of Immunology, Institute for Life and Medical Sciences, Kyoto University

WS31-18-P

NADPH oxidase regulates the stability of regulatory T cells and the development of autoimmunity〇 Hiroki Satooka, Takako Hirata
Department of Fundamental Biosciences, Shiga University of Medical Science

WS31-19-P

FOXM1 regulates fibrotic activity of skin fibroblasts derived from patients with systemic sclerosis〇 Tomoaki Higuchi, Yasushi Kawaguchi
Division of Rheumatology, Department of Internal Medicine, Tokyo Women’s Medical University School of Medicine

WS31-20-P

Functional differences between brain and spinal cord Tregs and tissue repair〇 Mahiro Watnabe, Minako Ito, Ako Matsui
Division of Allergy and Immunology, Kyusyu University, Fukuoka, Japan156

Awards Ceremony and Lectures

Awards Ceremony and Lectures
12 月 7 日（水） Wednesday, 7th December
各賞授賞式・受賞講演

Awards Ceremony and Lectures
日本免疫学会功労会員表彰式 / Commendation Ceremony for JSI Meritorious Member
功労会員（2023 年度 2 名）
Meritorious Member（2023, 2 members）
清野

宏

氏

Dr. Hiroshi Kiyono
山本

一彦

氏

Dr. Kazuhiko Yamamoto

第 25 回日本免疫学会賞授賞式 / 25th JSI Award Ceremony
第 25 回日本免疫学会賞受賞者
25th JSI Award Winner「免疫炎症・骨破壊の動態解明」“Study of immune cellular dynamics in vivo”
石井優氏（大阪大学大学院医学系研究科 免疫細胞生物学教室）

Dr. Masaru Ishii, Osaka University

第 9 回日本免疫学会ヒト免疫研究賞授賞式 /9th JSI Human Immunology Research Award Ceremony
第 9 回日本免疫学会ヒト免疫研究賞受賞者
9th JSI Human Immunology Research Award Winner「腫瘍微小環境の免疫制御機構の解明と新規がん免疫療法への展開」“Elucidation of immunosuppressive mechanisms in the tumor microenvironment for successful cancer
immunotherapy”
西川博嘉

氏（名古屋大学大学院医学系研究科 微生物・免疫学講座 分子細胞免疫学）

Dr. Hiroyoshi Nishikawa, Nagoya University

159

第 9 回日本免疫学会女性免疫研究者賞授賞式 /9th JSI Women Immunologist Award Ceremony
第 9 回日本免疫学会女性免疫研究者賞受賞者
9th JSI Women Immunologist Award Winner「制御性 T 細胞と樹状細胞による免疫制御の研究」“The role of regulatory T cell-dendritic cell crosstalk in immune regulation”
山崎

小百合

氏（名古屋市立大学大学院医学研究科 免疫学）

Dr. Sayuri Yamazaki, Nagoya City University※各種授賞式に引き続き、受賞講演を行います。
*The above Award Lectures will start following the ceremonies.

第 17 回日本免疫学会研究奨励賞授賞式 / 17th JSI Young Investigator Award Ceremony
第 17 回日本免疫学会研究奨励賞受賞者（五十音順）
17th JSI Young Investigator Award Winners「恒常性を制御する自然免疫ダイナミズムの解明」“Elucidation of innate immune dynamism maintaining homeostasis”
金山

剛士

氏（東京医科歯科大学 難治疾患研究所 生体防御学分野）

Dr. Masashi Kanayama, Tokyo Medical and Dental University「新たな自己反応性 T 細胞の産生・分化機構ならびに免疫学的機能の解明」“Homeostatic mechanisms and functional significance of a novel, self-reactive T lymphocyte population”
河部

剛史

氏（東北大学大学院医学系研究科 病理病態学講座 免疫学分野）

Dr. Takeshi Kawabe, Tohoku University「RNA 編集による免疫制御機構の解明」“Immune regulation by RNA editing”
中濱

泰祐

氏（大阪大学大学院医学系研究科 神経遺伝学教室）

Dr. Taisuke Nakahama, Osaka University「死細胞由来分子による腫瘍免疫微小環境制御機構の解析」“Regulation of immunosuppressive network at the tumor microenvironment by dead-cell derived molecules”
半谷匠

氏（東京大学先端科学技術研究センター 炎症疾患制御分野）

Dr. Sho Hangai, The University of Tokyo「腸管の粘膜免疫機構と微生物叢の解析を基盤とした疾患制御法の開発」“Regulation of intestinal bacteria-mediated diseases by antigen-specific mucosal immune responses andmetagenomic data”
藤本康介

氏（大阪公立大学大学院医学研究科・医学部 メタゲノム解析研究センター ゲノム免疫学）

Dr. Kosuke Fujimoto, Osaka Metropolitan University※研究奨励賞受賞者の研究課題については、12 月 8 日（木）16 時 55 分からポスター発表をいたします。
*JSI Young Investigator Award Winners' posters discussion will start at 16:55 on 8th December.
160

International Immunology Outstanding Merit Award Ceremony
International Immunology Outstanding Merit Award for 2021 Winner“Selective expression of claudin-5 in thymic endothelial cells regulates the blood-thymus barrier and T-cell export”
Dr. Takahiro Nagatake, Meiji University

若手免疫学研究支援事業 / Outstanding Young Immunology Researcher Award Winners Introduction
2022 年若手免疫学研究支援事業受賞者（五十音順）
Outstanding Young Immunology Researcher Award 2022 Winners「抗ウイルス免疫応答を制御する線維芽細胞サブセットの同定」“Identification of fibroblast subsets that regulate antiviral immune responses”
小泉真一

氏（九州大学 生体防御医学研究所）

Dr. Shinichi Koizumi, Kyushu University「腸内細菌および免疫系が脳発生・脳発達に及ぼす影響の解明」“Elucidation of the effects of microbiota and the immune system on the brain development”
宮島

倫生

氏（慶應義塾大学医学部 解剖学教室）

Dr. Michio Miyajima, Keio University「濾胞性ヘルパー T 細胞による胚中心維持・収束の分子基盤の解明」“Molecular mechanisms of germinal center maintenance and termination regulated by T follicular helper cells”
森大輝

氏（大阪大学 感染症総合教育研究拠点）

Dr. Daiki Mori, Osaka University

若手女性研究者研究支援事業 / Outstanding Young Women Researcher Award Winners Introduction
2022 年若手女性研究者研究支援事業受賞者（五十音順）
Outstanding Young Women Researcher Award 2022 Winners“Investigation of the role of B-cell-intrinsic TBK1 for germinal center formation”
Dr. Lee Michelle Sue Jann, The University of Tokyo「自己免疫寛容構築における胸腺 T 前駆細胞由来樹状細胞の役割の解明」“Investigation of the role of Thymic T progenitor cell-derived dendritic cells in establishing self-tolerance”
和田はるか

氏（北海道大学 遺伝子病制御研究所 免疫生物分野）

Dr. Haruka Wada, Hokkaido University1612022 年度「きぼう」プロジェクト 免疫学博士課程学生支援 採択者紹介 /“Kibou Projects 2022” Scholarship for Doctoral Students in Immunology Winners Introduction
阿比留龍喜

氏（東京大学）

Mr. Ryuki Abiru, The University of Tokyo伊東加織

氏（東北大学）

Ms. Kaori Ito, Tohoku University
伊藤直人

氏（東京理科大学）

Mr. Naoto Ito, Tokyo University of Science岡本翔太

氏（大阪大学）Mr. Shota Okamoto, Osaka University河合真悟

氏（慶應義塾大学）

Mr. Shingo Kawai, Keio University
栗原新奈

氏（東京大学）

Ms. Nina Kurihara, The University of Tokyo佐藤皓祐氏（東北大学）

Mr. Kosuke Sato, Tohoku University田中

麗華氏（東京大学）

Ms. Reika Tanaka, The University of Tokyo
山﨑貴弥

氏（横浜市立大学）

Mr. Takaya Yamasaki, Yokohama City University
安藤雄太郎

氏（東京大学）Mr. Yutaro Ando, The University of Tokyo亀井萌百氏（近畿大学）

Ms. Momo Kamei, Kindai University※「きぼう」プロジェクト免疫学博士課程学生支援の採択者の研究課題については、12 月 8 日（木）16 時 55 分からポスター発表をいたします。
* “Kibou Projects” Scholarship for Doctoral Students in Immunology Winners' Poster discussion will start at 16:55 on 8th
December.

162

Technical SeminarTechnical Seminar
11:45-12:45, Wednesday, December 7

T01

Technical Seminar 01

Room B: Civic Hall

T01-01Development of CAR technology coping with cancer immune evasion
Koji Tamada Department of Immunology, Yamaguchi University Graduate School of Medicine
T01-02Aiming for the development of effective cell therapy for solid tumors
Yoshihiro Miyahara Department of Personalized Cancer Immunotherapy, Mie University Graduate School of Medicine
Sony Corporation
11:45-12:45, Wednesday, December 7

T02

Technical Seminar 02

Room E: Conference Room A3

Chairperson: Yuki Kagoya (Aichi Cancer Center Research Institute)

T02-01 CRISPR screening in immune cells: from manipulation to application
Kalvin Sahota Horizon Discovery Biosciences Limited
Horizon Discovery K.K.
11:45-12:45, Wednesday, December 7

T03

Technical Seminar 03

Room F: Conference Room A4

Chairperson: Kiyoshi Hirahara (Graduate School of Medicine, Chiba University)

T03-01 3D chromatin structure dynamics during dendritic cell differentiation and activation
Daisuke Kurotaki Laboratory of Chromatin Organization in Immune Cell Development, IRCMS, Kumamoto University
TOMY DIGITAL BIOLOGY CO., LTD.
11:45-12:45, Wednesday, December 7

T04

Technical Seminar 04

Room H: Conference Room D1&D2

T04-01 40+ true high-parameter imaging protein analyses
Rieko Ikeda Standard BioTools K.K.
T04-02 New insights in the pathogenesis of atopic dermatitis and sarcoidosis
Kenji Kabashima Department of Dermatology, Kyoto University School of Medicine
Standard BioTools K.K.
165

11:45-12:45, Thursday, December 8

T05

Technical Seminar 05

Room E: Conference Room A3

Chairperson: Mamoru Harada (Department of Immunology Shimane University Faculty of Medicine)T05-01 Novel CAR-T Cell Platform for Treatment of Solid Tumors
Koji Tamada Yamaguchi University Graduate School of Medicine
Beckman Coulter K.K.
11:45-12:45, Thursday, December 8

T06

Technical Seminar 06

Room H: Conference Room D1&D2

T06-01

Study of disorder-specific macrophage subtypes -Towards understanding the mechanismof fibrosis onsetTakashi Satoh Department of Immune Regulation, Graduate School and Faculty of Medicine, Tokyo Medical and Dental University (TMDU)
Thermo Fisher Scientific

11:45-12:45, Thursday, December 8

T07

Technical Seminar 07

Room I: Conference Room E1&E2

T07-01

Quantifying the power of the immune system to fight cancer using the Incucyte(R)Live-Cell Analysis Platform
Nicola Bevan Manager, Cell Imaging Applications, SARTORIUS
SARTORIUS JAPAN K.K.

11:45-12:45, Friday, December 9

T08

Technical Seminar 08

Room C: Conference Room A1

T08-01Novel approaches to immunology research using image enabled cell analysis and sorting~ 次世代 高速イメージングセルソーターのご紹介、“ソーティングを次のステージへ”~
A Middlebrook BD Biosciences, San Jose, CA
Nippon Becton Dickinson Company, Ltd.

166

11:45-12:45, Friday, December 9

T09

Technical Seminar 09

Room G: Conference Room C1&C2

Chairperson: Shintaro Tanaka (Leica Microsystems K.K.)

T09-01 New normal of fluorescence microscopy and fluorescence lifetime imaging
Nobuhide Tsurumaki Leica Microsystems K.K.
T09-02 New normal of fluorescence microscopy and fluorescence lifetime imaging
Suguru Osari Leica Microsystems K.K.
Leica Microsystems K.K.

167

Clinical Seminar

Clinical Seminar
11:45-12:45, Wednesday, December 7

C01 Clinical Seminar 01

Room C: Conference Room A1

Chairperson: Hiroaki Dobashi (Department of Internal Medicine, Division of Hematology, Rheumatology andRespiratory Medicine, Faculty of Medicine, Kagawa Univ)

Reconsidering IL-6 receptor inhibition in autoimmune arthritis -Relation to neutrophils,
their extracellular traps, and citrullinated proteins in jointsIsao Matsumoto Department of Rheumatology, Faculty of Medicine, University of Tsukuba

C01-01

C01-02 Remission with rheumatoid arthritis treatment
Katsuya Suzuki Division of Rheumatology, Department of Internal Medicine, Keio University School of Medicine
CHUGAI PHARMATICAL CO., LTD.
11:45-12:45, Wednesday, December 7

C02 Clinical Seminar 02

Room D: Conference Room A2

Chairperson: Yutaka Kawakami (Department of Immunology, School of Medicine, International University of
Health and Welfare)C02-01 Patient stratification and optimization of combined immunotherapy
Shohei Koyama Division of Cancer Immunology, Research Institute/Exploratory Oncology Research & Clinical Trial Center (EPOC), National
Cancer / Department of Respiratory Medicine and Clinical Immunology, Osaka University Graduate School of Medicine

MSD K.K.
11:45-12:45, Wednesday, December 7

C03 Clinical Seminar 03

Room G: Conference Room C1&C2

Chairperson: Takanori Kanai (School of Medicine, Department of Internal Medicine (Gastroenterology andHepatology), Keio University)

C03-01 Intestinal immunity and the treatment of inflammatory bowel disease.
Yohei Mikami Division of Gastroenterology and Hepatology, Department of Internal Medicine, Keio University School of Medicine
C03-02 Importance of Treat-to-Target Strategies in Inflammatory Bowel DiseaseToshimitsu Fujii Tokyo Medical and Dental University, Department of Gastroenterology and Hepatology
Janssen Pharmaceutical K.K. / Mitsubishi Tanabe Pharma Corporation17111:45-12:45, Thursday, December 8

C04 Clinical Seminar 04

Room B: Civic Hall

Chairperson: Takanori Kanai (School of Medicine, Department of Internal Medicine (Gastroenterology andHepatology), Keio University)

C04-01

Recent progress of integrin research and integrin-targeted therapeutics for immune
diseases
Tatsuo Kinashi Department of Molecular Genetics, Institute of Biomedical Science, Kansai Medical University
Takeda Pharmaceutical Company Limited

11:45-12:45, Thursday, December 8

C05 Clinical Seminar 05

Room C: Conference Room A1

Chairperson: Tetsuji Sawada (TOKYO MEDICAL UNVERSITY HOSPITAL)

C05-01 Advances in Muti-omic research on Rheumatoid Arthritis
Katsuya Suzuki Division of Rheumatology, Department of Internal Medicine Keio University School of Medicine
C05-02 Treatment Strategy for Rheumatoid Arthritis Patients with Chronic Kidney Disease
Naoki Sawa Departments of Nephrology and Rheumatology Toranomon Hospital
ASAHI KASEI Pharma
11:45-12:45, Thursday, December 8

C06 Clinical Seminar 06

Room D: Conference Room A2

Chairperson: Takahiko Horiuchi (Kyushu University Beppu Hospital , Department of Rheumatology, Hematology
and Metabolic Diseases)

C06-01 The pathogenesis and treatment strategy for rheumatoid arthritis
Michihito Kono Department of Rheumatology, Endocrinology and Nephrology, Faculty of Medicine and Graduate School of Medicine, Hokkaido
University

C06-02 Intestinal Immunity and JAKs
Atsushi Mizoguchi Chairman and Professor, Department of Immunology, Kurume University School of Medicine
Pfizer Japan Inc172

11:45-12:45, Thursday, December 8

C07 Clinical Seminar 07

Room F: Conference Room A4

Chairperson: Takuji Iwamoto (Department of orthopedic surgery, Keio University School of Medicine)

C07-01 The role of RANKL in bone and the immune system
Hiroshi Takayanagi Department of Immunology Graduate School of Medicine and Faculty of Medicine The University of TokyoDAIICHI SANKYO COMPANY, LIMITED
11:45-12:45, Friday, December 8

C08 Clinical Seminar 08

Room G: Conference Room C1&C2

C08-01Developing therapies to target immune regulation: towards antigen-specificimmunosuppression
Shimon Sakaguchi Laboratory of Experimental Immunology, WPI Immunology Frontier Research Center, Osaka University
Otsuka Pharmaceutical Co., Ltd.

11:45-12:45, Friday, December 9

C09 Clinical Seminar 09

Room B: Civic Hall

Chairperson: Tsutomu Takeuchi (Vice President of Saitama Medial University/Emeritus Professor, Keio University)

C09-01

Progress in treatment strategies for spondylarthritis: precision medicine for psoriatic
arthritis
Yoshiya Tanaka The First Department of Internal Medicine, University of Occupational and Environmental Health, Japan
Novartis Pharma K.K.,

11:45-12:45, Friday, December 9

C10 Clinical Seminar 10

Room D: Conference Room A2

Chairperson: Takanori Kanai (Department of Gastroenterology and Hepatology, Keio University School of
Medicine)

C10-01 Cancer immunotherapy and tumor microenvironment
Yosuke Togashi Department of Tumor Microenvironment, Faculty of Medicine, Dentistry and Pharmaceutical Sciences , Okayama University
ONO PHARMACEUTICAL CO., LTD173

11:45-12:45, Friday, December 9

C11 Clinical Seminar 11

Room E: Conference Room A3

Chairperson: Kenji Kabashima (Graduate School of Medicine and Faculty of Medicine Kyoto University)

C11-01
Discovery Story: Journey to the Birth of Upadacitinib
JOCHENG SALFELD AbbVie GK Vice President Immunology & Virology Discovery Research ABC/CRC Site Head Distinguished Research Fellow
C11-02 Upadacitinib, a Janus-kinase inhibitor, for the treatment of atopic dermatitis
Tetsuya Honda Department of Dermatology, Hamamatsu University School of Medicine
AbbVie GK
11:45-12:45, Friday, December 9

C12 Clinical Seminar 12

Room F: Conference Room A4

Chairperson: Masato Kubo (RIKEN/Tokyo University of Science)

Multiple inflammatory cytokines shape the pathogenicity of memory CD4+ T cells during
chronic allergic inflammation
Kiyoshi Hirahara Department of Immunology, Graduate School of Medicine, Chiba University

C12-01

C12-02 Distinct roles for IL-4 and IL-13 in type 2 inflammation
Ariel Munitz Department of Clinical Microbiology and Immunology, Faculty of Medicine, Tel Aviv University
Specialty Care Medical, Sanofi K.K.

174

Clinical Evening Seminar

Clinical Evening Seminar
19:30-20:45, Wednesday, December 7

CE01 Clinical Evening Seminar 01

Room F: Conference Room A4

Chairperson: Tsutomu Takeuchi (Vice President of Saitama Medial University/Emeritus Professor, Keio University)

CE01-1

Andomized comparison between reduced dose and maximum tolerable dose ofconcomitant methotrexate at adalimumab initiation in patients with rheumatoid
arthritis with inadequate response to methotrexate; MIRACLE study
Hiroya Tamai Division of Rheumatology, Department of Internal Medicine, Keio University School of Medicine

CE01-2 Optimal use of methotrexate in the management of rheumatoid arthritis
Yuko Kaneko Division of Rheumatology, Department of Internal Medicine, Keio University School lof Medicine
Eisai Co., Ltd.

177

Afternoon Seminar

Afternoon Seminar
12:55-13:55, Thursday, December 7

A01 Afternoon Seminar 01

Room B: Civic Hall

Chairpersons: Shigeo Koyasu (RIKEN Center for Integrative Medical Sciences, Laboratory for Immune Cell Systems)
Akihiko Yoshimura (School of Medicine, Department of Microbiology and Immunology, Keio Univesity)

A01-01

T follicular helper cells in blood mirror salivary gland-infiltrating T cells in primary
Sjogren's syndrome

Saori Abe Department of Rheumatology, Institute of Medicine, University of Tsukuba

A01-02

Localization of T cells in lymphoid tissues and expression of Regnase-1 contribute to
the development of autoimmune diseases
Keiko Yasuda Department of Medical Chemistry, Graduate School of Medicine, Kyoto University
TOMY DIGITAL BIOLOGY CO., LTD.

12:55-13:55, Thursday, December 8

A02 Afternoon Seminar 02

Room B: Civic Hall

Chairpersons: Shigeo Koyasu (RIKEN Center for Integrative Medical Sciences, Laboratory for Immune Cell Systems)
Akihiko Yoshimura (School of Medicine, Department of Microbiology and Immunology, Keio Univesity)

A02-01 Fatty acid metabolism in the generation of memory precursor population of CD4+T cells
Yusuke Endo Laboratory of Medical Omics Research, KAZUSA DNA RESEARCH INSTITUTE
A02-02

Group 2 innate lymphoid cells exacerbate allergic inflammation by increasing allergic
susceptibility
Yasutaka Motomura Laboratory for Innate Immune Systems, Department of Microbiology and Immunology, Graduate School of Medicine,
Osaka University / Laboratory for Innate Immune Systems, Osaka University Immunology Frontier Research Center(IFReC) / Laboratory for Innate Immune Systems, RIKEN IMS

A02-03Tumor-infiltrating PD-1+ effector T cells and reguratory T cells as novel biomarkers
and therapeutic targets for cancer immunotherapies
Yosuke Togashi Department of Tumor Microenvironment, Faculty of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University
Nippon Becton Dickinson Company, Ltd.

181

Evening SeminarEvening Seminar
19:30-20:45, Wednesday, December 7

E01

Evening Seminar 01

Room C: Conference Room A1細胞と免疫免疫学の進むべき道
座長：茂呂 和世（大阪大学医学系研究科）

pDC は何者か？
座長：樗木 俊聡（東京医科歯科大学）

E01
Cruising in the cell
Atsushi Miyawaki RIKEN Center for Brain Science Laboratory for Cell Function Dynamics / RIKEN Center for Advanced Photonics
Biotechnological Optics Research Team

Moderna Japan Co., Ltd
19:30-20:45, Wednesday, December 7
OD E02

Evening Seminar 02

脳神経代謝と免疫

Room D: Conference Room A2神経回路と免疫系の新たなクロストーク学の創成にむけてゲートウェイ反射による組織特異的炎症誘導機構
座長：村上 正晃（北海道大学遺伝子）

中枢神経系の免疫・非免疫機能を司る多様なマクロファージ
座長：増田 隆博（九州大学薬学研究科）

臓器間ネットワークによる個体レベルでの恒常性維持機構の解明と代謝疾患制御片桐 秀樹 東北大学大学院医学系研究科糖尿病代謝内科学分野

E02

Moderna Japan Co., Ltd185

19:30-20:45, Wednesday, December 7

E03 Evening Seminar 03
感染と免疫

Room E: Conference Room A3

ウイルス学と免疫学のコラボの最適解

新型コロナウイルスの進化
座長：佐藤 佳（東京大学医科学研究所）

次のパンデミックに１００日でワクチンを世界に提供するには？
座長：石井 健（東京大学医科学研究所）

E03

Addressing the threat of emerging viral infections

河岡 義裕

National Center for Global Health and Medicine / University of Tokyo / University of Wisconsin-Madison

Moderna Japan Co., Ltd
18:45-20:00, Thursday, December 8
OD E04

Evening Seminar 04

Room C: Conference Room A1

RNA 創薬 ～免疫学との接点～
RNA 創薬 ～免疫学との接点～
座長：竹内 理（京都大学）

mRNA 創薬 ～パンデミックからの学び～
座長：萩原 百合子（モデルナ・ジャパン）

E04

mRNA therapeutics: Present and future位髙 啓史

東京医科歯科大学

生体材料工学研究所 / 大阪大学

感染症総合教育研究拠点

Moderna Japan Co., Ltd186

18:45-20:00, Thursday, December 8
OD E05

Evening Seminar 05

Room D: Conference Room A2

合成情報生物と免疫
合成免疫学の魅力～免疫系は「調べる」時代から「創る」時代へ～
座長：伊川 友活（東京理科大学生命医科学研究所）

機能ゲノム学による自己免疫疾患の病態解明
座長：石垣 和慶（理化学研究所）

E05

HD Video Recorder of the Cell

谷内江 望

UBC, University of British Columbia School of Biomedical Engineering (SBME)

Moderna Japan Co., Ltd
18:45-20:00, Thursday, December 8

E06 Evening Seminar 06

Room E: Conference Room A3

再生医療と免疫細胞を薬剤として使う戦略：現状と課題
座長：河本 宏（京都大学）

単純化のすゝめ
座長：山崎 聡（筑波大学, 医学医療系）

E06
ヒト肝臓オルガノイドを用いた代謝・炎症性肝疾患研究
Takebe Takanori Institute of Research, Tokyo Medical and Dental University / Communication Design Center, Yokohama City University /Center for Stem Cell and Organoid Medicine, Cincinnati Children's Hospital Medical Center / Division of Gastroenterology,
Hepatology and Nutrition and Division of Developmental Biology, Cincinnati Children's Hospital Medical Center Professor,
Tokyo Medical and Dental University

Moderna Japan Co., Ltd187

18:45-20:00, Thursday, December 8
OD E07

Evening Seminar 07

Room F: Conference Room A4

老化・AI と免疫T 細胞の老化疲弊と老化関連疾患
座長：吉村 昭彦（慶應義塾大学）

数理モデルによる CAR シグナルの挙動の予想と新規 CAR の構築
座長：近藤 泰介（NCI, USA）

E07

老化に伴う慢性炎症病態と免疫中西 真 Institute of Medical Science, University of Tokyo

Moderna Japan Co., Ltd

188

Young Academy Program

Young Academy Program
20:05-21:15, Thursday, December 8

若手座談会（フォーラム）Room B: Civic Hall

免疫学の未来若手研究者を中心にキャリアパスや研究について語り合いましょう！
企画、進行：鈴木 忍（京都大学）
ア シ ス ト：安藤 眞（慶應義塾大学）、田中 ゆり子（東邦大学）、角南 理己（京都大学）、安田 圭子（京都大学）
共登

催：免疫若手アカデミー
壇

者：免疫若手アカデミーメンバー他

191日本免疫学会からのお知らせ特定非営利活動法人日本免疫学会からのお知らせ
1. 学会のホームページアドレス
日本免疫学会から会員の皆様へのお知らせは、ホームページを通じて行っておりますので、随時ご覧ください。

ホームページアドレス：https://www.jsi-men-eki.org/
2. 会員への電子メールによる情報配信について
日本免疫学会では、電子メールにて、会員の皆様への緊急なお知らせやお願いを配信しております。未だメール
アドレスを会員データベースに登録されていない方は、至急会員専用ページ (https://www.men-eki.org/meneki_web/
jsp/welcome.html) よりご登録いただくか、学会事務局（info@meneki.or.jp）へご連絡ください。

3. 会費納入について
本学会は、10 月 1 日より、新年度（2023 年度 <2022 年 10 月 1 日～ 2023 年 9 月 30 日 >）となりました。新年度の会費は、学会事務局より送付いたしました「年会費用振替用紙」にてお振込みいただくか、会員専用ページ（https://www.men-eki.org/meneki_web/jsp/welcome.html）より簡便なクレジットカードによる会費決済をおこなえますので、より多くの会員の皆様にご利用をお願い申し上げます。クレジットカード決済の際に、年会費と併せて寄附金を納付いただける場合に限り、クレジット手数料は無料（全額学会負担）となります。
新規入会の方は、学会ホームページ「入会申込」のボタンより、オンラインで手続きをお願いいたします。

4. 2023 年度

特定非営利活動法人日本免疫学会役員（各五十音順）

理事長：小安重夫（2022 年 12 月 31 日迄）黒崎知博
（2023 年 1 月 1 日から 2024 年 12 月 31 日迄）理 事：久保允人、黒崎知博、反町典子、中山俊憲、三宅健介、山崎 晶、吉村昭彦
（2022 年 12 月 31 日迄）岡田峰陽＊、椛島健治、河本 宏、熊ノ郷 淳、渋谷 彰、高柳 広、竹田 潔、三宅幸子、山崎 晶＊
（2023 年 1 月 1 日から 2024 年 12 月 31 日迄）
荒瀬 尚、石井 健、樗木俊聡、大野博司、渋谷和子、新藏礼子、竹内 理
（2023 年 1 月 1 日から 2026 年 12 月 31 日迄）＊
理事長推薦理事につき 2022 年 12 月 14 日開催の通常総会にて承認後
監 事：清野 宏、山本一彦
（2022 年 12 月 31 日迄）
小安重夫、岩倉洋一郎
（2023 年 1 月 1 日から 2024 年 12 月 31 日迄）

5. 日本免疫学会へのご寄附のお願い
ご存じのとおり、本学会は、2005 年度の NPO 法人化を機に、社会貢献活動にも積極的に取り組み、「免疫ふしぎ未来」
をはじめとして、一般社会に対して、より広く免疫学の魅力と重要性をアピールする活動も広げ、免疫研究への一層の理解と、啓蒙に努めております。
その一方で、収入の減少及び消費税値上げ等により、実質的な資産の減少が著しく、これまで、各種事業の見直し等、学会として対応策を講じてまいりましたが、年々、健全な学会運営をとりまく環境は厳しくなっております。
皆様のご協力のお蔭で、本学会は 2016 年 11 月 7 日をもちまして、本認定特定非営利活動法人として認定されましたが、本認定期間においても、より多くの方々（毎年 100 名以上）からの寄附があることが認定継続の要件となっております。
つきましては、今後、社会へのより一層の貢献のために、各種事業による免疫学の普及啓発事業等の活動をさらに発展させ、本学会の財政健全化のためにも、より多くの皆様からの寄附を募集いたします。
寄附のお申し込みの詳細につきましては、本学会ホームページ、ご寄附のお願い（https://www.jsi-men-eki.org/
kifu/）をご覧ください。クレジットカードでのお支払いも可能です。また、会員専用ページ (https://www.men-eki.
org/meneki_web/jsp/welcome.html) より、年会費と併せて寄附金を納付いただければ、クレジット決済手数料は無料（全額学会負担）となりますので、本学会活動にご理解とご賛同をいただき、ご支援・ご協力をいただければ幸いです。
なお、本学会の主たる目的である業務に関係する寄附金は、個人・法人ともに税法上の優遇措置が与えられます。
ご不明な点等ありましたら、下記の学会事務局までお問い合わせください。

6. 特定非営利活動法人 日本免疫学会 事務局
〒 101-0024 東京都千代田区和泉町 1-4-2 KUMAKI ビル 2F
電話 : 03 (5809) 2019   FAX: 03 (5809) 2089   e-mail: info@meneki.or.jp
（文責 :

195

事務局長

浅井保至）

Author Index○ : PresenterA
A. Begum, Nasim
Abe, Fumie
Abe, Nobuya
Abe, Saori
Abe, ShinyaAbe, Yoshiaki
Abo, Hirohito
Adachi, Takahiro

WS08-10-O/P
WS05-14-O/P
WS15-05-O/P
A01-01
WS21-02-O/P
WS02-21-P
WS16-11-P○WS08-16-O/P
WS19-19-O/P
WS21-18-P
Adachi, Takumi
WS03-17-P
WS07-15-O/P
Adachi, Yu
WS12-02-P
WS12-05-P
Afi, Candra Trinugraha
WS14-10-P
Agata, Yasutoshi
WS10-11-P
WS26-08-O/P
Agawa, Kyosuke
WS03-22-P
Agemura, Tomoya ○WS20-21-P
Ahmad, Ijaz
WS06-03-O/P
WS31-14-P
Aihara, Tetsu
WS31-08-O/P
Ainai, Akira
WS12-06-O/P
Akahori, Yasushi
WS11-26-P
Akama, Yuichi
WS05-20-P
Akari, Hirofumi
WS28-20-P
Akasaka, Yuki
WS28-25-P
Akashi, Kouichi
WS23-08-O/P
Akashi-Takamura, Sachiko○WS08-22-O/P
WS13-14-O/P
WS13-19-P
WS30-18-P○S09-01
Akdis, Cezmi○WS18-09-P
Aki, Daisuke
Akiba, Hisaya
WS21-11-P
Akimitsu, Kazuya
WS29-23-P
Akira, Shizuo
WS02-27-O/P
Akita, Hirofumi
WS23-13-O/P
Akiyama, Mitsuhiro WS10-15-P
Akiyama, Nobuko
WS24-19-O/P
WS24-20-O/P
Akiyama, Taishin
WS24-19-O/P
WS24-20-O/P
Al-Habsi, Muna
WS27-04-P○WS27-14-O/P
Amagai, Masayuki ○S09-04
WS06-01-O/P
WS09-01-O/P
WS09-04-O/P
WS09-05-O/P
Amano, Koichi
WS16-14-P
Amitani, Hanae
WS11-08-P○WS27-23-O/P
An, Jianbo
An, Ning
WS02-13-P
Anastasakis, Dimitrios

S06-03○WS21-05-O/P
WS13-07-O/P○WS11-04-O/P
WS11-03-P○WS04-07-P
Ando, Miki
Ando, Tomoaki
WS04-16-O/P
WS09-09-O/P○WS19-02-O/P
WS21-06-O/P
WS23-09-O/P○WS02-12-P
Ando, Yukie
WS27-09-P
Andoh, Tsugunobu WS09-20-P
Annoura, Takeshi
WS12-10-P○WS06-18-P
Ano, Tomoko
Aoki, Hiroyasu
WS02-01-P○WS10-06-O/P
WS18-24-P○WS02-08-O/P
Aoki, Takahiro○WS16-04-O/P
Arai, Masaya○S04-05
Arai, Satoko
Arakaki, Rieko
WS04-08-O/P
WS15-06-O/P
Araki, Akemi
WS14-08-P○S01-03
Arase, Hisashi
WS03-04-O/P
WS03-08-O/P
WS03-12-P
WS24-10-O/P
WS28-02-O/P
WS30-04-P
WS31-05-O/P
WS31-07-O/P
Ardianto, Bambang ○WS11-25-P
Ariki, Shimpei
WS07-09-P
WS17-16-P○WS25-02-P
WS03-13-P
WS12-25-P
Arima, Masafumi
WS09-19-P
Arita, Makoto
WS09-01-O/P
WS21-05-O/P
Ariyoshi, Akito
WS12-24-P
Armytasari, Inggar WS11-25-P○WS19-09-P
Arong, Gaowa
Artyomov, Maxim ○S12-03○WS26-05-O/P
Asa, Minori○WS22-20-P
Asahi, Takuma
Asahina, Ryota
WS07-20-P
Asahina, Yasuhiro
WS23-13-O/P
Asami, Shohei
WS08-14-O/P
Asano, Kenichi
WS20-05-O/P
Asano, Yoshimasa ○WS30-11-P
Asanuma, Hideki
WS13-17-O/P
Asao, Atsuko
WS27-07-P
Asao, Hironobu
WS14-08-P
WS22-11-P○WS05-17-O/P
Asaoka, MasatoAndo, Daisuke
Ando, KiyoshiAndo, Makoto

Asashima, Hiromitsu○WS18-25-P
Ashikari, Tsubasa ○WS09-16-P
WS21-05-O/P
Askenase, Philip
WS14-07-P
Atarashi, Koji
WS16-15-O/P
Atsumi, Tatsuya
WS15-05-O/P
WS17-06-O/P
Atsumi, Toru
WS19-10-P○WS10-25-P
Awata, Natsumi
Ayabe, Tokiyoshi
WS19-11-P
Aydinok, Yesim
S06-03○WS02-24-P
Ayukawa, Shiyu○WS17-03-O/P
Azuma, Mitsuki
WS18-17-P
WS26-02-O/P
WS26-11-P
WS26-12-P
Azuma, Miyuki
WS10-19-P
WS16-17-P
WS24-08-P
WS27-22-P

B○WS17-05-O/P
WS05-19-P
WS04-15-P
WS22-07-O/P
WS08-07-O/P
WS08-18-P
WS13-06-O/P
WS24-12-P
WS30-06-P
Badger Wing, James WS16-13-P○WS08-03-P
Bai, Jie
Baicheng, Fan
WS24-11-O/P
Bamba, Takeshi
WS18-06-O/P
Bassik, Michael C WS14-18-P
WS22-01-O/P
Bäumler, Andreas J. WS12-12-O/P
Bayarsaikhan, Ganchimeg○WS03-24-P
WS10-04-O/P
Ben Arous, Juliette WS12-01-P
Benjaskulluecha, Salisa
WS04-17-P
WS29-05-O/P
Bernard, Brady
WS27-16-O/P○T07-01
Bevan, Nicola
Biswas, Mrityunjoy ○WS30-18-P
WS08-22-O/P
WS13-14-O/P
Biswas, Shashwata WS28-10-P
Blumberg, Richard S. WS19-19-O/P
Boonmee, Atsadang○WS04-17-P
WS29-05-O/P
Baba, Hiroyuki
Baba, RieBaba, Takeshi
Baba, Tomohisa
Baba, Yoshihiro

196

Boonyaleka, Kotchakorn○WS14-02-P
Bosselut, Remy
WS18-04-O/P
Brenner, Malcolm K WS26-06-O/P
Brewer, R. Camille S11-05
Bryne, Ryan
WS02-07-O/P
Bustamante, Jacinta S06-03

CCai, Zimeng
WS18-05-O/P
Caruso, Roberta
S10-05
Casanova, Jean-Laurent
S06-03
Casilag, Fiordiligie WS12-03-P
Cella, Marina
WS20-19-O/P
Chalalai, Thanyakorn WS03-13-P
WS07-09-P○WS12-25-P
WS17-16-P
WS25-02-P
Chamberlain, SamuelWS03-08-O/P○S12-01
Chamoto, Kenji
WS24-02-O/P
WS26-03-O/P
WS27-04-P
WS27-14-O/P
Chang, Jen-Chien WS05-17-O/P○WS23-02-O/P
Chang, Jingjie○WS18-23-P
Chao, Ruoyu
Che, Jingru
WS28-16-P
Chen, Ming-Han ○WS06-07-O/P○S11-03
Chen, Shih-Yu
WS02-28-P
Cheroutre, Hilde
WS01-03-O/P
Chiba, Asako
WS08-03-P
WS22-12-P
Chiba, Hirofumi
WS18-11-P
Chiba, Kenji
WS25-10-P
Chiba, Shigeru
WS02-21-P
Chigusa, Yoshitsugu WS29-20-P
Chikuma, Shunsuke WS11-03-P
WS16-09-O/P○WS18-19-P
Chompoowong, Rajit○WS06-11-P
Chong, Yee Kien ○WS04-14-P
WS18-08-O/P
Chowdhury, Sajid Iftekhar
WS08-22-O/P○WS13-19-P
WS30-18-P
Christie, Tanisha
WS27-16-O/P
Christine, Christine WS11-25-P
Chung, Soo-Hyun
WS06-12-P
Chunhaphinyokul, Benyapa
WS12-21-P

Ciucci, Thomas
Coban, Cevayir

Coffelt, SethColl, Lluis
Colonna, Marco
Conway, Simon J
Corti, Davide
Croft, Adam

WS18-04-O/P
WS03-02-O/P
WS07-12-P
WS12-18-O/P
WS27-18-P
WS28-24-P
WS02-07-O/P
WS27-27-P
WS20-19-O/P
WS09-20-P○S01-05○S02-02

D
D'Alessandro-Gabazza, Corina N.
WS06-18-P
WS25-14-P
WS27-01-P
Dang, Son Tung
WS26-16-P○S16-02
Daniel, Mucida
Daroonpan, Pissacha○WS27-22-P○WS28-24-P
Dash, Rashmi
Deborah, Elfira Amalia○WS05-03-O/P
Del Rosario Zorrilla, Camila
WS03-02-O/P○WS24-02-O/P
Delghandi, Sara
Denda, Tamami
WS04-06-O/P
Denda-Nagai, Kaori S09-03
Deshpande, Neha R. WS26-18-P
Dewayani, Astri
WS07-09-P
Dik, Willem A.
WS06-08-O/P
WS06-10-P
WS06-11-P
Doki, Yuichiro
WS10-09-P○WS21-14-P
Dotake, Yoichi
Dowell, Alexa K.
WS02-17-P
Dunne, Philip
WS02-07-O/P
Dusold, Justyn
WS11-11-O/P

E
E O’Leary, Claire
WS05-06-O/P○S04-02
Eberl, Gerard
Ebihara, Nobuyuki WS09-09-O/P
WS19-02-O/P
Ebihara, Takashi
WS05-05-O/P
WS21-01-O/P
Ebihara, Takeshi
WS23-15-P
Edwards, Joanne
WS02-07-O/P
Egami, Shohei
WS06-01-O/P
Egashira, Shiori
WS07-15-O/P
Egawa, Gyohei
S11-02
WS10-13-P
Eguchi, Hidetoshi
WS10-09-P
Ejiri, Naoko
WS09-20-P
Ekronarongchai, Supanuch○WS06-08-O/P
En, Kunbai
WS27-03-P
Endo, Ayaka
WS16-15-O/P
Endo, Katsunori
WS01-07-O/P○WS01-19-P
Endo, Kyoko
WS06-17-P

Endo, Mikiko
Endo, YukihiroEndo, Yusuke

Enya, Takuji
Enya, Takuji
Eto, Koji

WS27-12-P
WS11-08-P○WS01-13-P
WS01-16-P
WS02-04-O/P
WS05-11-O/P
WS18-21-P
WS26-07-O/P○A02-01
WS08-05-P
WS15-03-O/P
WS23-04-O/P

F
Fagarasan, Sidonia S12-01
WS27-04-P
WS27-14-O/P○S07-05
Farber, Donna○S05-05
Feuerer, Markus
Fioravanti, Jessica WS02-02-O/P
Flahou, Charlotte ○WS23-04-O/P
Fleming, Mark
S06-03Fox, Bernard
WS31-11-P
Fox, Bernard A.
WS02-17-P
Fridman, Valeria
WS25-13-O/P
Fridman D'Alessandro, Valeria
WS06-18-P
Fridman-D'Alessandro, Valeria
WS25-14-P
Fuchimukai, Akane WS05-05-O/P
WS21-01-O/P
Fuji, Yushiro
WS19-06-P
Fujihara, Shinichi
WS13-17-O/P
Fujii, Kaho
WS11-01-P
Fujii, Kentaro
WS08-20-O/P
Fujii, Shin-Ichiro
WS02-08-O/P
WS03-11-P
WS11-18-P
WS25-17-O/P○C03-02
Fujii, Toshimitsu
Fujikawa, Rintaro ○WS03-25-P○WS13-05-O/P
Fujimori, Sota
Fujino, Masayuki
WS02-05-P
Fujio, Keishi
WS13-03-O/P
WS15-08-O/P
WS25-12-O/P○WS11-23-O/P
Fujioka, Mayu
WS18-03-O/P○WS05-08-P
Fujioka, Naoto
Fujioka, Shusei
WS11-23-O/P○WS18-03-O/P○S13-04
Fujisaki, Joji
Fujisaki, Keiko
WS13-15-P○WS22-05-O/P
WS22-21-P
Fujisawa, Manabu WS02-21-P
Fujisawa, Masahiro WS02-22-P
Fujisawa, Sotaro ○WS03-09-O/P
Fujita, Yasuyuki
WS02-23-P
Fujita, Yuki
WS09-11-P
WS17-11-O/P○WS21-20-P
Fujiwara, Hiroshi
WS11-26-P
Fujiwara, Kentaro ○WS01-10-P
Fujiwara, Yukio
WS11-14-O/P

Fujiwra, Mitsuhiro
Fukao, Saori
Fukase, Koichi

WS08-17-P
WS13-12-P
WS13-13-O/P
WS30-03-O/P
Fukase, Saaya
WS09-09-O/P
WS19-02-O/P
Fukawa, Akika
WS14-16-P
Fukaya, Tomohiro ○WS07-02-P
WS20-17-P
WS27-08-P
Fukuda, Keitaro
WS09-01-O/P
Fukuda, Saori
WS04-10-P
WS04-18-P
Fukuda, Shinji
WS22-03-O/P
Fukuda, Tetsuya
WS27-15-P
Fukuhara, Takataro WS01-18-P
WS17-09-O/P
Fukui, Ryutaro
WS02-27-O/P
WS29-11-O/P○WS05-16-O/P
Fukui, Takuma
Fukui, Yoshinori
WS09-08-O/P
WS17-09-O/P
Fukunaga, Koichi
WS05-19-P
WS11-03-P○WS17-07-P
Fukuoka, Ayumi
Fukushima, Sayaka ○WS13-02-P
Fukushima-Nomura, Ayano
WS06-01-O/P○WS09-04-O/P
FUKUYAMA, Satoru WS21-12-P
Funakoshi, Shogo WS31-08-O/P
Funatsu, Shotaro
WS16-03-P
Funatsu, Takashi
WS25-12-O/P
Furudoi, Keiko
WS26-23-P
Furuhashi, Kazuhiro S13-04
Furuhata, Erina
WS22-13-P
Furuhata, Masae
WS11-21-P
WS26-06-O/P
WS26-10-P
Furukawa, Atsushi WS30-04-P
Furukawa, Kyoji
WS26-23-P
Furukawa, Mutsumi WS19-20-O/P
Furukawa, Ryutaro WS02-06-O/P
WS23-12-P○WS28-14-P
Furukawa, Shoko
WS23-06-P
Furusawa, Yukihiro WS14-11-O/P
WS30-17-P
Furusawa, Yuri
WS28-01-O/P
Furuta, Shunsuke
WS05-15-P

G
Gabazza, Corina
Gabazza, Esteban

WS25-13-O/P
WS25-13-O/P
WS25-14-P
Gabazza, Esteban C WS06-18-P
Gabazza, Esteban C. WS27-01-P○WS02-22-P
Gao, Tong
Geier, Christoph
WS10-16-P
Genevieve, David
S06-03Gilfillan, Susan
WS20-19-O/P○S14-04
Gilliet, Michel
Gohda, Jin
WS28-09-P
WS28-12-P
Goitsuka, Ryo
WS13-15-P

197

WS22-05-O/P
WS22-21-P
Goto, Hiroyasu
WS04-19-P○WS14-04-P
WS29-19-P
Goto, Yumiko
WS26-15-P
Goto-Matsumoto, Naomi
WS02-20-O/P○WS11-20-O/P
Gou, Qiao
Graham, Daniel
WS07-04-O/P
Graham, Gerard
WS17-07-P
Griffin, Sue
WS27-16-O/P
Guerrini, Matteo
WS23-03-O/P○WS27-02-P
Guo, Haochen○WS05-13-P
Guo, YunH○WS26-16-P
Ha, Thi Viet My
Habu, Sonoko
WS16-10-P
Habuchi, Tomonori WS11-16-P
Hachimura, Satoshi WS19-23-P
Hachisu, Masakazu WS09-16-P
WS20-10-O/P
Hachiya, Tsuyoshi WS06-09-P
Hafler, David
WS18-25-P
Hafner, Markus
S06-03
Hagen, P. Martin Van WS06-11-P
Hagihara, Yuya
WS22-24-P
Hagiwara, Yukitomo WS29-22-P
Hajime, Maiko
WS26-03-O/P
Hakata, Yoshiyuki
WS08-05-P
Haku, Yasuharu
WS26-03-O/P
Hamada, Akinobu
WS31-11-P
Hamada, Michito
WS29-18-P
Hamana, Hiroshi
WS26-09-O/P
WS26-16-P
WS28-03-O/P
WS31-08-O/P
Hamanishi, Junzo
WS11-23-O/P
Hamano, Yoshitomo ○WS31-09-P○OT12
Hamazaki, Yoko
○S12-04
WS12-04-O/P
Hana, Taijun
WS02-11-P
Hanaki, Hideaki
WS03-10-P
Hanami, Kentaro
WS15-14-P
Hanaoka, Hironari WS25-10-P
Hanayama, Rikinari WS02-26-P
WS03-04-O/P
WS10-07-O/P
WS31-04-O/P
Haniuda, Kei
WS08-14-O/P
WS08-15-P
WS13-12-P
Hara, Atsushi
WS10-06-O/P
WS23-12-P○S16-01
Hara, Eiji
○OT10
Hara, Hideki○S10-01
WS12-24-P
WS14-17-P
WS29-09-P
Hara, Hiromitsu
WS25-06-O/P
Hara, Takahiko
WS17-08-O/P○WS31-02-O/P
Hara, Yuki

Hara, Hiromitsu
Harada, Akihito
Harada, Hiroaki

WS09-12-P
WS08-18-P
WS15-08-O/P
WS25-05-O/P
Harada, Hironori
WS20-05-O/P○WS01-14-P
Harada, Junji
WS23-02-O/P
Harada, Kenichi
WS04-06-O/P
Harada, Mamoru
WS27-11-O/P○WS27-21-P
Harada, Michishige ○WS28-09-P
Harada, Narumi
WS08-09-O/P
Harada, Norihiro
WS21-11-P
Harada, Sonoko
WS21-11-P
Harada, Takuya
WS23-08-O/P○WS21-04-O/P
Harada, Yasuyo
Harada, Yohsuke
WS09-02-O/P
Harada, Yoshihiro
WS16-12-O/P○WS19-12-O/P
Harada, Yosuke
Harada, Yuka
WS20-05-O/P
Harata, Gaku
WS19-06-P
Harigae, Hideo
WS01-15-P
WS11-08-P
Harimoto, Kozo
WS06-19-P
Hase, Koji
WS06-05-O/P
WS09-18-P
WS16-07-O/P
WS19-18-O/P
WS20-04-O/P
WS24-16-P
WS19-14-O/P
Hasebe, Rie
WS15-05-O/P
WS19-10-P
Hasegawa, Atsuhiko○WS28-20-P○WS03-04-O/P
Hasegawa, Gen
Hasegawa, Hideaki WS17-13-O/P
Hasegawa, Hideki WS12-06-O/P
Hasegawa, Ichita
WS01-13-P
WS02-04-O/P
WS01-16-P
Hasegawa, Tatsuya WS10-11-P
Hashiguchi, Masaaki○WS19-21-P
Hashiguchi, Takao WS23-16-P
Hashimoto, Ayaka
WS27-07-P
Hashimoto, Hinata WS28-16-P
Hashimoto, Mayuko ○WS21-18-P
Hashimoto, Rina
WS08-01-O/P
Hashimoto, Ryuji
WS11-21-P
Hashimoto, Shinichi WS08-02-P
WS27-20-O/P
Hashimoto-Tane, Akiko
WS26-13-P○WS19-03-O/P
Hatai, Shunya
Hatakeyama, Shigetsugu
WS02-15-P
WS04-02-P○WS23-03-O/P
Hatano, Hiroaki
Hatano, Masahiko WS09-19-P
Hatano, Ryo
WS15-19-P○WS30-06-P
Hatano, Shinya
Hatazawa, Sara
WS02-12-P
WS27-09-P
Hatsuzawa, Saki
WS17-05-O/P○WS04-10-P
Hattori, Akito
WS04-18-P○WS11-21-P
Hattori, Ann

Hattori, Masahira
WS06-04-O/P
Hattori, Nobutaka
WS06-02-O/P
Hayabuchi, Hodaka ○WS16-09-O/P
Hayakawa, Taeko ○WS11-17-P
Hayakawa, Yoshihiro WS27-13-O/P
WS05-04-P
WS05-21-P
Hayama, Masaki
WS23-10-O/P
Hayashi, Fuzuki
WS09-10-P
WS09-15-P○WS24-14-P
WS29-03-P
WS29-04-P
Hayashi, Kazuhiko WS06-20-P
Hayashi, Tomonori WS23-14-P○WS26-23-P
Hayashi, Tomoya
WS27-18-P
Hayashi, Yoshihiro WS20-05-O/P
Hayashizaki, Koji
WS05-11-O/P
Hayatsu, Norihito
WS26-04-O/P
Hayday, Adrian
WS02-07-O/P○WS26-09-O/P
Hayee, Abdul
WS26-16-P
Hayman, Hannah
WS02-07-O/P
Hazama, Shunsuke WS28-25-P○WS05-04-P
He, Ka○WS12-03-P
Heiss, Kirsten
Hemmi, Hiroaki
WS29-10-O/P
Hérou, Célia
WS12-01-P○S15-01
Hess, Christoph
Hiai, Hiroshi
WS24-03-P
Hida, Ayumi
WS26-23-P
Hidai, Riko
WS04-10-P○WS04-18-P○WS13-08-P
Hidaka, Reiko
Higasa, Koichiro
WS17-09-O/P
Higashi, Natsumi
WS23-04-O/P
Higashiyama, Haruka○WS11-12-P
Higashiyama, Mizuki WS08-14-O/P○WS08-15-P
Higgins, Matthew
WS03-08-O/P
Higuchi, Masaya
WS12-21-P○WS03-12-P
Higuchi, Shuhei
WS31-07-O/P
Higuchi, Tomoaki ○WS31-19-P
Hikida, Masaki
WS13-02-P
WS28-21-P
Hikosaka-Kuniishi, Mari
○WS22-10-O/P
WS22-23-P
Himeda, Toshiki
WS12-21-P
Hino, Masayuki
WS27-06-P
Hioki, Kou
WS27-18-P
Hirahara, Kiyoshi ○S04-03
WS12-07-O/P
WS21-13-P○C12-01
Hirahara, Mizuki
WS04-10-P
WS04-18-P
Hirahata, Koichi
WS23-16-P
Hirai, Hirofumi
WS27-01-P
Hirai, Toyohiro
WS23-16-P
Hiraide, Kyoga
WS07-05-O/P○WS10-21-P
Hirakawa, Mayumi WS20-12-P○WS22-06-O/P
Hiramoto, Kazuoto WS25-10-P

Hirankarn, Nattiya

WS06-08-O/P
WS06-10-P
WS06-11-P
Hirano, Asuka
WS21-10-P○WS01-01-O/P
Hirano, Ken-Ichi
WS13-07-O/P○S03-05
Hirano, Naoto○WS11-24-P
Hirano, Takeshi
Hiranuma, Ryosuke ○WS14-09-O/P
Hiraoka, Yasuaki
WS18-03-O/P
Hirata, Hirokuni
WS09-19-P
Hirata, Jun-Ichi
WS28-12-P
Hirata, Takako
WS31-01-O/P
WS31-18-P
Hirata, Yuichi
S13-04
Hiratsuka, Hiroyuki ○WS11-26-P
Hirayama, Kenji
WS12-10-P
Hirayama, Takehiro WS15-01-O/P○WS15-04-O/P
Hirayasu, Kouyuki WS03-04-O/P
WS30-04-P
Hiroki, Mukoyama
WS07-08-P○WS27-03-P
Hirose, Shiho
Hirota, Keiji
WS07-08-P
WS15-09-O/P
WS25-09-O/P
Hisaeda, Hajime
WS12-19-P
Hisato, Riku
WS08-15-P
Hisatome, Ichiro
WS14-16-P○WS13-01-O/P
Hiwa, Ryosuke
Hiyoshi, Hirotaka ○WS12-12-O/P
Ho, Ping-Chih
WS27-27-P
Ho, Tuyen Thuy Bich WS11-15-P
Hoehn, Kenneth
WS18-25-P
Hohjoh, Hirohiko
WS06-06-O/P○WS17-06-O/P
Hojyo, Shintaro
WS19-10-P
Honda, Haruka
WS13-02-P○OT16
Honda, Kenya
Honda, Naoki
WS21-21-P○OT14
Honda, Tetsuya
WS07-20-P
WS09-07-O/P
C11-02
Honda, Yoshitaka
WS29-10-O/P
Honda, Yuko
WS09-20-P
Honda Keith, Yuki
WS07-20-P
Honjo, Tasuku
S12-01
WS08-10-O/P
WS18-18-P
WS24-02-O/P
WS24-03-P
WS26-03-O/P
WS27-04-P
WS27-14-O/P
WS31-16-P
Hontsu, Shigetp
WS11-19-P
Honzawa, Tatsuma ○WS25-01-P○S05-04
Hori, Shohei
WS09-12-P
WS10-03-O/P
WS16-01-O/P
WS16-03-P
WS26-04-O/P○WS24-19-O/P
Horie, Kenta
Horiguchi, Shuhei ○WS22-25-P
Horii, Kazuyoshi
WS28-25-P
Horii, Takayuki
WS27-18-P

198

Horii, Yumi

WS04-13-O/P
WS24-15-O/P
Horitani, Shunsuke ○WS01-18-P
WS17-09-O/P
Horiuchi, Takahiko WS15-03-O/P
Horiuchi, Yutaka
WS02-12-P○WS27-09-P
Hoshikawa, Koki
WS28-25-P
Hoshino, Katsuaki WS29-11-O/P○WS29-23-P
Hoshino, Tomoaki
WS07-15-O/P
Hoshino, Yasunobu WS06-02-O/P
Hoshino, Yoshihiko WS26-22-P
Hoshiya, Yoshimichi ○WS31-03-O/P
Hoshizaki, Midori
WS27-23-O/P
WS28-05-O/P
Hosokawa, Hiroyuki WS01-01-O/P
WS01-12-P
Hosokawa, Takanatsu
WS16-07-O/P
Hosomi, Koji
WS09-07-O/P
WS13-13-O/P
WS19-03-O/P
WS30-03-O/P
Hosomi, Kosuke
WS22-12-P
Hosono, Akira
WS19-23-P○WS18-06-O/P
Hosono, Yuki
Hosoya, Tadashi ○WS12-06-O/P
WS17-05-O/P
Hotta, Akitsu
WS23-04-O/P
Hozumi, Katsuto
WS01-01-O/P
WS01-12-P
WS13-07-O/P○WS02-05-P
Hu, XinHuang, Yin
WS02-02-O/P○WS13-10-O/P
Huang, Yuming
Huizar, John P.
WS13-01-O/P
Husain, Afzal
WS08-10-O/P○S05-03
Huseby, Eric
Huynh, Hiep Hung ○WS29-06-O/P

I○WS10-04-O/P
WS04-07-P○WS27-17-P
WS09-06-O/P
WS18-11-P
WS25-08-P○WS31-01-O/P
Ichioka, Satoko○WS16-02-O/P
Ichiyama, KenjiIde, Takuma
WS04-16-O/P
Idei, Akiko
WS28-09-P
Igarashi, Kazuhiko WS08-19-O/P
Igarashi, Naoya
WS14-11-O/P○WS29-12-P○WS18-12-P
Iida, Kazuma○WS27-11-O/P
Iida, Yuichi
WS27-21-P
Iijima, Hideki
S16-03
Iizasa, Ei'Ichi
WS09-12-P○WS15-17-P
Iizuka, Mana
Iizuka, Yuki
WS09-16-P
Ikawa, Tomokatsu
WS11-10-O/P
WS13-07-O/P
WS20-12-P
WS22-06-O/P
Ibraheem, Yarob
Ichihara, Gaku
Ichikawa, Juri
Ichikawa, Saori
Ichimiya, Shingo

Ikeda, Eriko

WS20-01-P○WS04-20-P
Ikeda, Kei
WS05-15-P
Ikeda, Mari
WS11-03-P
WS28-11-P
Ikeda, Mizuko
WS03-16-P○WS20-05-O/P
Ikeda, Naoki○WS19-05-P
Ikeda, Ryo
Ikeda, Rieko
T04-01
Ikeda, Shigaku
WS09-06-O/P
Ikeda, Yoshiki
WS01-18-P
WS17-09-O/P
WS22-09-O/P
WS22-17-P
Ikeda, Yumi
WS15-12-P
WS25-10-P
Ikeda-Ohtsubo, Wakako
WS03-18-P
Ikegami, Ippei
WS18-11-P
WS25-08-P○WS19-06-P
Ikegami, Mion
○WS30-02-P
Ikegawa, Moe
Ikeo, Kazuho
WS08-02-P
WS27-20-O/P
WS31-09-P
Ikeo, Taira
WS27-01-P
Ikuta, Koichi
WS21-02-O/P
WS22-20-P○WS24-03-P
Ikuta, Naoko
Imadome, Ken-Ichi WS28-15-P
Imafuku, Tadashi
WS08-02-P
Imagawa, Ryotaro WS02-20-O/P○WS14-01-P
Imai, Masaki
WS16-13-P
Imai, Masaki
WS28-01-O/P
Imai, Shota
WS02-26-P
WS10-07-O/P○WS31-04-O/P
Imai, Wakana
WS17-03-O/P
WS26-02-O/P
Imai, Yumiko
WS27-23-O/P○WS28-05-O/P
Imaizumi, Misa
WS26-23-P
Imamura, Akihiro
WS18-06-O/P
Imamura, Kosuke
WS11-14-O/P
Imamura, Mitsuru
WS25-05-O/P
Imamura, Takeshi
WS06-20-P
Imanishi, Takayuki ○WS18-01-O/P
Imoto, Yusuke
WS18-03-O/P
Imura, Yoshitaka
WS18-16-P
Inaba, Mutsumi
WS18-05-O/P
Inagaki, Shingo
WS11-15-P
Inagaki-Ohara, Kyoko○WS19-08-P
Ino, Hajime
WS04-13-O/P○WS24-15-O/P
Inohara, Naohiro
S10-05
WS19-04-P
Inohaya, Asako
WS29-20-P
Inoue, Akiko
WS31-15-P
Inoue, Chisa
WS06-18-P
WS25-13-O/P
WS25-14-P
Inoue, Hiromasa
WS21-14-P
Inoue, Jun-Ichiro
WS28-09-P
Inoue, Shin-Ichi
WS03-24-P
WS10-04-O/P
Inoue, Tadahiko
WS19-19-O/P○S07-01
WS08-07-O/P
WS12-05-P
Inui, Masanori
WS08-22-O/P
WS13-14-O/P
WS30-18-P
Irie, Atsushi
WS08-11-O/P
WS19-05-P○WS05-09-P
Irie, Emi
Irie, MisatoWS05-19-P○WS27-26-P
Irie, Takuma
Irimura, Tatsuro
S09-03
Isaka, Yoshitaka
WS10-20-P○WS10-18-P
Ise, Marii
WS26-14-P
WS31-15-P
Ise, Wataru
WS08-20-O/P
Iseki, Ken
WS14-07-P
Iseki, Masanori
WS13-16-P
Isezaki, Masayoshi WS03-09-O/P○WS10-13-P
Ishibashi, Mami
Ishibashi, Mariko ○WS27-19-P
Ishibashi, Riko
WS30-17-P
Ishida, Hideaki
WS12-09-P
Ishida, Hideharu
WS18-06-O/P
Ishida, Ryosuke
WS17-05-O/P
Ishida, Sayaka
WS04-21-P○WS17-15-P
Ishida, Yuko
WS25-16-O/P
Ishido, Satoshi
WS28-12-P○WS19-16-P
Ishifune, Chieko
Ishigaki, Hirohito
WS12-09-P
WS29-21-P
Ishigaki, Kazuyoshi WS23-03-O/P○WS10-15-P
Ishigaki, Sho
Ishihama, Yasushi WS19-14-O/P
Ishihara, Jun
WS27-02-P
Ishihara, Katsuhiko ○WS13-16-P
Ishihara, Rino
WS22-24-P
Ishihara, Ryo
WS04-15-P○WS02-10-P
Ishii, Ayana
Ishii, Keiko
WS03-07-O/P
Ishii, Ken
WS28-15-P
WS30-15-P
Ishii, Ken J.
WS03-02-O/P
WS27-18-P
WS28-24-P○S08-03
Ishii, Masaru
WS04-21-P
WS08-20-O/P
WS11-01-P
WS16-16-P
WS20-04-O/P
WS20-20-O/P
WS20-21-P
WS29-16-P
Ishii, Naoto
WS01-06-O/P
WS01-15-P
WS07-05-O/P
WS10-21-P
WS17-03-O/P
WS18-04-O/P
WS18-14-P
WS18-20-P
WS26-02-O/P
WS26-11-P
WS26-12-P
WS27-07-P
Inoue, Takeshi

Ishii, Takashi
Ishii, Yumiko
Ishikawa, Eri

WS21-15-P○WS21-12-P
WS05-01-O/P
WS18-06-O/P
Ishikawa, Fumihiko WS11-07-O/P
WS11-08-P
WS22-04-O/P
Ishikawa, Hiroki
WS05-10-P
Ishikawa, Junichi ○WS05-15-P
Ishikawa, Mizuki
WS13-02-P
Ishikawa, Tatsuya ○WS24-20-O/P
Ishikura, Asaki
WS16-11-P
Ishimaru, Naozumi WS04-08-O/P
WS15-06-O/P
WS15-07-O/P
WS15-18-P
WS24-01-O/P
WS31-10-P
Isogai, Shuntaro
WS15-16-P
WS23-07-P○WS26-19-P
Isogawa, Masanori WS12-02-P
Itahashi, Kota
WS27-26-P○E04
Itaka, Keiji
Ito, Daisuke
WS28-22-P
Ito, Emi
WS03-06-O/P○WS05-01-O/P
Ito, Fuyu
WS31-09-P
Ito, Hiroaki
WS11-23-O/P○WS28-22-P
Ito, Hiroyasu
Ito, Isao
WS23-16-P
Ito, Junya
WS07-17-O/P○WS20-02-O/P
WS21-08-O/P
Ito, Kandai
WS21-05-O/P○WS19-20-O/P
Ito, Kaori○WS04-04-O/P
Ito, Koyu
Ito, Mamoru
WS23-05-P
Ito, Masataka
WS06-19-P○S15-02
Ito, Minako
WS10-22-P
WS10-23-P
WS10-25-P
WS16-12-O/P
WS31-20-P
Ito, Mutsumi
WS28-01-O/P
Ito, Naoto
WS04-07-P
WS20-10-O/P
WS20-11-P○WS20-12-P
WS21-05-O/P
Ito, Sachio
WS02-22-P
Ito, Seigo
WS04-19-P
WS14-04-P
WS20-16-P
Ito, Taiki
WS10-10-P
Ito, Toshihiro
WS02-06-O/P
WS10-06-O/P
WS11-19-P
WS23-06-P
WS23-12-P
WS28-14-P
Ito, Yoshihiro
WS09-01-O/P
Itoh, Takumi
WS15-19-P
Itoh, Yasushi
WS12-09-P
WS29-21-P
Itoh-Nakadai, Ari ○WS11-07-O/P
WS11-08-P

199

WS22-04-O/P○WS15-01-O/P
WS04-10-P
WS04-18-P
WS05-02-P
WS05-12-P
Iwabuchi, Sadahiro ○WS08-02-P
Iwagami, Yoshifumi WS10-09-P
Iwai, Hideyuki
WS12-06-O/P○WS15-10-P
Iwai, Tamaki
WS15-20-P
Iwai, Yoshiko
WS19-21-P
Iwakura, Yoichiro
WS06-12-P○WS02-17-P
Iwamoto, Noriko
WS31-11-P
Iwamoto, Taro
WS05-15-P○WS23-16-P
Iwamoto, Yayoi○WS12-07-O/P
Iwamura, Chiaki
Iwanaga, Shiroh
WS03-08-O/P
WS28-24-P
Iwasaki, Akiko
WS18-25-P
Iwasaki, Hiroyuki
WS08-14-O/P○WS26-20-P
Iwasaki, Kenta○WS22-04-O/P
Iwasaki, Makoto
Iwasaki, Motoki
WS06-09-P
Iwasaki, Natsumi
WS23-16-P
Iwata, Arifumi
WS05-15-P
WS18-12-P
WS21-17-P
Iwata, Ayaka
WS20-05-O/P
Iwata, Kentaro
WS05-09-P○WS22-24-P
Iwata, Shigeru
WS15-14-P
Iwata, Takashi
WS27-10-O/P
Iwatani, Koyo
WS17-03-O/P
Iwatsuki, Ken
WS19-07-P
Iwatsuki-Horimoto, Kiyoko
WS28-01-O/P
Iyoda, Masayuki
WS05-10-P
Iyoda, Tomonori
WS02-08-O/P
Iyori, Mitsuhiro
WS28-16-P
Izawa, Kazushi
WS29-10-O/P
Izawa, Kumi
WS04-16-O/P
WS19-02-O/P
WS21-06-O/P
WS23-09-O/P
WS09-09-O/P
Izumi, Yoshihiro
WS18-06-O/P
Itotagawa, Eri
Iwabuchi, Kazuya

J
Jankovic, Dragana WS18-04-O/P
Jeong, Ae Jin
WS02-25-P
Jian, Jiun-Yu
WS12-10-P○WS24-10-O/P
Jin, Hui
WS28-02-O/P
Jing, Huie
S06-03○WS12-04-O/P
Jo, Norihide
Jo, Tatsunori
WS15-01-O/P○WS24-18-P
WS30-19-O/P
Jo-Watanabe, Airi
WS29-15-O/P
June, Carl
WS11-05-O/P
Junichi, Kikuta
WS29-16-P

K
Kabashima, Kenji

S11-02
WS07-20-P
WS09-07-O/P
WS10-13-P
WS25-06-O/P○T04-02
Kabata, Hiroki
WS05-17-O/P○WS05-19-P
Kadoki, Motohiko ○WS07-04-O/P
Kadomatsu, Tsuyoshi WS30-04-P
Kadowaki, Norimitsu WS02-27-O/P
Kagechika, Hiroyuki WS17-05-O/P
Kageyama, Takahiro WS05-15-P
WS18-12-P
WS21-17-P
Kagoshima, Yomei WS03-13-P
WS07-09-P
WS12-25-P
WS17-16-P
WS25-02-P○S03-04
Kagoya, Yuki
WS11-02-P
WS11-06-O/P○WS15-18-P
Kai, Tamura
Kaibori, Yuito
WS19-11-P
Kaifu, Tomonori
WS28-23-P
Kaisho, Tsuneyasu ○S06-02
WS06-05-O/P
WS27-15-P
WS29-10-O/P
WS29-11-O/P○WS04-16-O/P
Kaitani, Ayako
WS09-09-O/P
WS19-02-O/P
WS21-06-O/P
WS23-09-O/P
Kaitani, Ryota
WS22-02-O/P○WS22-14-P
Kaji, Emi
WS03-14-P○WS03-16-P
WS03-23-P
WS12-15-P
Kajihara, Nabeel ○WS27-25-P
Kakiuchi, Miwako
S13-04
Kaku, Yu
WS28-10-P
Kakugawa, Kiyokazu○WS01-03-O/P
Kakuo, Shingo
WS14-05-P
Kakuta, Hiroki
WS20-04-O/P○T02-01
Kalvin, Sahota○WS01-12-P
Kama, Yuichi
Kamada, Haruhiko WS18-18-P
WS31-16-P
Kamatani, Takashi WS05-19-P
WS20-05-O/P
Kamba, Tomomi
WS11-14-O/P
Kamei, Anna
WS21-06-O/P○WS04-09-P
Kamei, Momo
WS27-05-P
Kamekura, Ryuta
WS18-11-P
WS25-08-P
Kametani, Yoshie
WS26-15-P○WS05-11-O/P
Kamii, Yasuhiro○WS09-06-O/P
Kamijo, Seiji
Kamimura, Daisuke WS17-06-O/P
Kamioka, Mariko ○WS07-12-P

Kamioka, Yuji

WS01-18-P
WS17-09-O/P
WS22-09-O/P○WS22-17-P
Kamita, Yukako
WS24-03-P
Kamitani, Wataru
WS28-15-P
Kamiya, Atsunori
WS17-11-O/P
Kamiya, Mari
WS12-06-O/P○WS30-13-O/P
Kamiya, Shiori
WS18-11-P
WS25-08-P
Kamiya, Atsunori
WS21-20-P
Kamiyama, Naganori○WS03-13-P
WS07-09-P
WS12-25-P
WS17-16-P
WS25-02-P
Kamoshita, Nagisa WS02-24-P○WS29-18-P
Kanai, Maho
○S02-03
Kanai, Takanori
WS05-09-P
WS13-05-O/P
WS18-15-P
WS19-12-O/P
WS22-24-P
WS24-17-O/P
Kanameishi, Shuto ○WS07-20-P
Kanaseki, Takayuki WS02-16-P
WS02-18-P
WS11-13-P
Kanayama, Masashi○S13-05
Kanda, Hidenori
WS10-05-O/P
Kanda, Ryuichiro
WS15-14-P○WS11-22-P
Kanda, Yasuhiro
Kaneda, Kenta
WS29-22-P
Kaneko, Mitunori
WS23-08-O/P
Kaneko, Shin
WS23-04-O/P
Kaneko, Shuichi
WS11-15-P
Kaneko, Shun
WS23-13-O/P
Kaneko, Yuko
WS10-15-P
WS15-12-P
WS25-10-P
CE01-2
Kanekura, Takuro
WS09-12-P
WS25-06-O/P
Kanemaru, Kazumasa○S09-03
Kanemitsu, Keiji
WS14-07-P
Kang, Chae Myung WS02-25-P○WS30-17-P
Kani, Koudai
Kannagi, Mari
WS28-20-P
Kanno, Akiko
WS26-15-P
Kanno, Emi
WS03-07-O/P
Kanno, Masamoto WS05-13-P
Kanno, Takayuki
WS12-06-O/P
Kanno, Toshio
WS05-11-O/P
WS18-21-P○WS26-07-O/P○WS29-01-O/P
Kano, Norisuke
Kan-O, Keiko
WS21-12-P
Kanou, Shunka
WS01-16-P
Kanto, Tatsuya
WS23-13-O/P
Karasuyama, Hajime WS07-17-O/P
WS09-11-P
WS20-02-O/P
WS21-08-O/P

Karen, Saiki
WS03-19-P
Karimzadeh, Alborz WS26-18-P○WS14-11-O/P
Kasai, Kaichi
WS29-13-P
Kasajima, Rika
WS27-24-O/P
Kasamatsu, Jun
WS03-07-O/P○WS20-19-O/P
Kashima, Soki
WS11-16-P
Kashiwagi, Hirofumi WS26-15-P
Kashiwakura, Jun-Ichi
WS08-06-P
WS17-02-P○WS04-02-P
Kasuga, Yusuke○WS11-02-P
Kasuya, Hitomi
Kasuya, Tadamichi WS04-05-P
Kasuya, Yuzo
WS04-20-P
WS20-01-P○E02
Katagiri, Hideki
Katagiri, Mayuka
WS20-12-P○WS20-11-P
Katagiri, Ryoko
WS06-09-P
Katagiri, Takaharu WS19-04-P
Katahira, Yasuhiro
WS17-13-O/P
Katakai, Tomoya
WS11-22-P○WS22-19-P○WS23-05-P
Katano, Ikumi
Kato, Azusa
WS04-19-P
WS14-04-P
WS20-16-P○WS29-19-P
Kato, Daiki
WS27-10-O/P○WS13-12-P
Kato, KeiKato, Naohiro
WS26-23-P
Kato, Shingo
WS27-17-P○WS29-10-O/P
Kato, Takashi
Kato, Tamotsu
WS12-19-P
Kato, Yasuhiro
WS14-06-O/P
WS15-01-O/P
Katoh, Yuki
WS02-20-O/P○WS27-10-O/P
Katsukura, Yuka
WS14-16-P
Katsumata, Yoshio ○WS07-10-P
Katsura, Yoshichika WS06-14-P
Kaufmann, Johanna WS27-16-O/P
Kawabata, Shigetada WS03-04-O/P
Kawabe, Takeshi
WS01-06-O/P
WS01-15-P
WS07-05-O/P
WS10-21-P○WS18-04-O/P
WS18-14-P
WS18-20-P
WS27-07-P
Kawabe, Tsutomu
WS09-10-P
WS09-15-P
WS24-14-P
WS29-03-P
WS29-04-P
Kawagishi, Hirokazu WS27-01-P○WS16-01-O/P
Kawagoe, Suzu
Kawaguchi, Atsushi WS10-02-O/P
Kawaguchi, Mariko WS17-15-P
Kawaguchi, Yasushi WS31-19-P
Kawahara, Shoya ○WS08-06-P
Kawahara, Yukio
WS30-10-P
Kawahata, Kimito
WS25-05-O/P○WS15-07-O/P
Kawahito, Yuki
WS15-18-P

200

Kawai, Shingo
Kawai, Taro

WS28-06-O/P
WS14-10-P
WS29-01-O/P
WS29-02-O/P
WS30-02-P
Kawajiri, Akihisa
WS01-06-O/P○WS01-15-P
WS07-05-O/P
WS18-04-O/P
WS18-14-P
WS18-20-P
WS27-07-P
Kawakami, Eiryo
WS09-01-O/P
WS09-04-O/P
Kawakami, Kazuyoshi
WS03-07-O/P
Kawakami, Ryoji ○WS01-05-O/P
WS16-04-O/P
Kawakami, Shigeru WS12-10-P
Kawakami, Yutaka WS27-10-O/P
WS02-20-O/P
Kawakatsu, Kumpei ○WS30-09-P
Kawakita, Masataka WS30-08-O/P
Kawamoto, Hiroshi ○OT03
WS01-10-P
WS01-11-P
WS13-07-O/P
WS13-08-P
WS22-02-O/P
WS22-14-P
WS22-16-P
WS22-18-P
WS26-08-O/P
WS31-17-P
Kawamura, Masami WS02-08-O/P
WS25-17-O/P
Kawamura, Takeshi WS23-06-P
Kawamura, Yosuke WS29-20-P
Kawano, Masaaki
WS25-05-O/P○WS20-03-P
Kawano, Yohei
WS24-08-P
WS28-18-P
Kawaoka, Yoshihiro WS28-01-O/P○E03
Kawasaki, Hiroshi
WS09-01-O/P
WS09-04-O/P
WS09-05-O/P
Kawasaki, Reiko
WS06-21-P
Kawasaki, Takumi
WS29-01-O/P○WS29-02-O/P
WS30-02-P
Kawase, Wataru
WS27-17-P
Kawashima, Hina
WS09-10-P
WS09-15-P
WS24-14-P
WS29-03-P
WS29-04-P
Kawashima, Hiroto WS16-11-P
Kawata, Daisuke
WS12-06-O/P
Kawata, Kazuhiko ○WS13-06-O/P
WS30-06-P
Kayama, Hisako
S16-03
WS07-11-P
WS17-14-P
Kenneth, Davie
WS13-13-O/P
WS30-03-O/P
Khadka, Sundar
WS06-03-O/P○WS31-14-P

○WS08-01-O/P
Khalil, Jumana
Khawsang, Chirayus WS06-08-O/P
Khueangchiangkhwang, Sukhonthip○WS12-17-P
Kihara, Miho
WS18-18-P
Kii, Shuhei
WS27-20-O/P
Kikuchi, Jun
WS25-10-P
Kikushige, Yoshikane WS23-08-O/P○WS04-21-P
Kikuta, Junichi
WS08-20-O/P
WS16-16-P
WS20-20-O/P
WS20-21-P
Kikutake, Chie
WS13-06-O/P
Kilbey, Anna
WS02-07-O/P
Kim, Kwang Soon
WS01-15-P
WS18-04-O/P
Kim, Lark Kyun
WS29-08-P
Kim, Seul-Ki
WS02-25-P○S14-03
Kim, Wan-Uk
Kim, Yun-Gi
WS09-18-P
Kimitsu, Toru
WS09-06-O/P
Kimura, Akari
WS29-18-P
Kimura, Akihiko
WS17-15-P
WS25-16-O/P
Kimura, Kazumi
WS03-24-P
WS10-04-O/P
Kimura, Masahiro
WS07-21-P○WS09-09-O/P
Kimura, Meiko
WS19-02-O/P
Kimura, Motoko
WS01-13-P
Kimura, Motoko Y
WS01-16-P
Kimura, Shunsuke WS19-14-O/P
WS19-18-O/P○WS28-06-O/P
Kimura, Toshiki
WS11-14-O/P
Kimura, Uki
WS01-21-P○WS03-19-P
Kimura, Yoshitaka ○WS30-12-P○WS28-19-P
Kimura, Yuta
Kinashi, Tatsuo
WS01-18-P
WS17-09-O/P
WS22-09-O/P
WS22-17-P○C04-01
Kinashi, Yusuke
WS16-07-O/P
WS19-14-O/P○WS19-18-O/P
Kiniwa, Tsuyoshi
WS05-07-O/P
Kinjo, Yuki
WS05-11-O/P
Kino, Hiroaki
WS27-02-P
Kinoshita, Manabu WS03-15-P
WS04-19-P
WS14-04-P
WS20-16-P
WS29-19-P
Kinoshita, Shota
WS10-02-O/P
Kinoshita, Tomohide○WS26-04-O/P
Kinugasa, Yasuha
WS28-05-O/P
Kishi, Hiroyuki
WS26-09-O/P
WS26-16-P
WS26-21-P
WS28-03-O/P
WS31-08-O/P
Kishikawa, Sari
WS03-14-P
WS03-16-P
WS03-23-P○WS12-15-P
Kishimoto, Hidehiro WS13-18-P
Kishino, Shigenobu WS04-07-P
Kiso, Maki
WS28-01-O/P
Kitabatake, Masahiro WS02-06-O/P
WS10-06-O/P
WS11-19-P
WS23-06-P○WS23-12-P
WS28-14-P
Kitagawa, Naoko
WS12-09-P
Kitahara, Genta
WS02-08-O/P
Kitahata, Kosuke ○WS25-07-P
Kitajima, Anna
WS03-10-P
Kitajima, Isao
WS09-20-P
Kitajima, Masayuki ○WS10-17-P
Kitajima, Midori
WS09-20-P
Kitajima, Yasuo
WS20-03-P
WS28-18-P
Kitamura, Daisuke WS08-14-O/P
WS08-15-P
WS13-11-O/P
WS13-12-P
WS08-07-O/P
Kitamura, Hidemitsu○WS27-20-O/P
Kitamura, Yuya
WS10-21-P○WS26-03-O/P
Kitaoka, Koji
Kitatani, Kazuyuki
WS21-10-P
Kitaura, Jiro
WS04-16-O/P
WS09-09-O/P
WS09-17-P
WS16-10-P
WS19-02-O/P
WS21-06-O/P
WS23-09-O/P
Kitazawa, Yusuke
WS20-18-P
Kitkumtorn, Nakarin WS06-11-P
Kiuchi, Masahiro ○WS21-13-P○WS07-13-P
Kiya, Naoko
Kiyono, Hiroshi
WS13-13-O/P
WS30-03-O/P
Kleinstein, Steven
WS18-25-P
Kobayashi, Eiji
WS26-09-O/P
WS26-16-P○WS26-21-P○WS17-02-P
Kobayashi, Fuki
Kobayashi, Hiroya WS27-20-O/P
Kobayashi, Koich
WS04-02-P
Kobayashi, Koichi
WS02-13-P
WS02-14-P
WS02-15-P
Kobayashi, Midori
WS02-08-O/P
Kobayashi, Mizuki WS11-16-P
Kobayashi, Nobuyoshi
WS27-18-P
Kobayashi, Noritada WS03-10-P○WS26-18-P
Kobayashi, Shio
Kobayashi, Shogo WS10-09-P
Kobayashi, Takashi WS03-13-P
WS07-09-P
WS12-25-P
WS17-16-P
WS25-02-P
Kobayashi, Takeshi WS10-05-O/P
Kobayashi, Takumi WS31-09-P
Kobayashi, Tetsuro WS05-08-P
WS05-17-O/P○WS07-16-O/P
Kobayashi, Tetsuya WS22-25-P○WS22-18-P
Kobayashi, Yuka
Kobayashi, Yutaro
WS10-25-P
Kobiyama, Kouji
WS27-18-P
WS28-15-P○WS27-01-P
Kobori, Hajime
Kochi, Yuta
WS24-12-P○WS24-17-O/P
Koda, Yuzo
Kodama, Naoki
WS04-07-P○WS05-06-O/P
Koga, Satoshi○WS29-24-P
Koga, Tomoaki○WS06-21-P
Koguchi, Ayako
Koguchi, Yoshinobu WS02-17-P○WS27-16-O/P
WS31-11-P
Kohda, Chikara
WS05-10-P
Kohwi-Shigematsu, Terumi
WS31-15-P
Kohyama, Masako WS03-12-P
WS28-02-O/P
WS31-05-O/P
WS31-07-O/P
Koida, Atsuhide
WS03-17-P
Koike, Eri
WS04-13-O/P
WS29-06-O/P○WS14-05-P
Koike, Natsumi○WS08-20-O/P
Koike, Takuya
Koinuma, Keita
WS01-15-P
WS10-21-P
Koiwai, Kazuki
WS04-19-P
WS29-19-P
Koizumi, Shinichi
WS05-16-O/P
Koizumi, Shini-Ichi ○WS07-14-P
Koji, Hase
WS28-06-O/P
Kojima, Hidefumi ○WS01-17-P
WS19-21-P
Kojima, Hirotatsu
WS08-13-O/P
Kojima, Naoya
WS10-12-P
Kojo, Satoshi
WS01-02-O/P
WS05-16-O/P
WS07-14-P
Kokubo, Kota
WS21-13-P
Komai, Toshihiko
WS13-03-O/P
Komaki, Shohei
WS06-09-P
Komatsu, Noriko ○OT01
Komatsu, Satoko ○WS26-15-P
Komatsu, Shuichiro WS23-01-O/P
Komatsu, Toshihiro ○WS02-19-P
WS31-08-O/P
Kometani, Kohei
WS08-20-O/P
Komiya, Yoji
WS12-06-O/P
Komiyama, Seiga ○WS06-05-O/P
WS16-07-O/P
Komohara, Yoshihiro WS11-14-O/P
WS19-05-P
Komori, Satomi
WS04-01-O/P○WS20-13-P
Komori, Tadasuke
WS17-15-P○WS12-21-P
Komuro, Akihiko
Konaka, Hachiro
WS15-04-O/P
Kondo, Hiroyuki
WS15-06-O/P○WS10-11-P
Kondo, Kenta
Kondo, Motonari
WS10-18-P
WS26-14-P
WS31-15-P
Kondo, Naoyuki
WS01-18-P
WS17-09-O/P

201○WS22-09-O/P
WS22-17-P○WS11-11-O/P
Kondo, Taisuke
Kondo, Toshikazu
WS08-02-P
WS17-15-P
WS25-16-O/P
Kondo, Yuma
WS17-05-O/P
Kondo, Yuya
WS15-10-P
WS15-11-P
WS15-20-P
Kondoh, Gen
WS07-08-P
WS15-09-O/P
WS25-09-O/P
WS28-13-P
Konnai, Satoru
WS03-09-O/P
Kono, Hajime
WS30-12-P
Kono, Michihiro
WS23-03-O/P○C06-01
Kono, Michihito
Kosaka, Shumpei
WS31-06-O/P
Kosako, Hidetaka
WS24-02-O/P
WS08-10-O/P
Koseki, Haruhiko
WS02-08-O/P
WS09-01-O/P
WS09-05-O/P
WS11-07-O/P
Koseki, Haruhiko
WS04-17-P
Kosuge, Masato
WS04-04-O/P
Kotaki, Ryutaro
WS12-02-P
WS12-05-P
Kotani, Ai
WS13-07-O/P
Kotani, Hitoshi
WS27-21-P
Kotani, Joji
WS03-22-P
Kotani, Takenori
WS04-01-O/P
WS20-13-P
Kotani, Yui
WS18-13-P
Kouwaki, Takahisa ○WS12-22-P
WS12-23-O/P
Koyama, Ryuki
WS17-12-O/P
Koyama, Shohei
WS27-26-P○C02-01
Koyama, Yoshinobu ○WS31-13-P
Koyasu, Shigeo
WS07-07-O/P
Kozai, Mina
WS18-05-O/P
Kozono, Haruo
WS24-11-O/P○WS24-11-O/P
Kozono, Yuko
Kozuma, Yukinori
WS08-12-P
Kronenberg, Mitchell WS19-13-O/P
Kuba, Keiji
WS27-23-O/P
Kubo, Akiko
WS27-10-O/P○OT07
Kubo, Masato
WS08-01-O/P
WS21-04-O/P
Kubo, Satoshi
WS31-06-O/P○WS05-07-O/P
Kubota, Kentaro
Kubota, Shimpei
WS19-10-P
Kubota, Yoshiaki
WS02-19-P
Kudo, Ikuru
WS18-23-P
Kueanjinda, Patipark WS04-17-P○S06-04
Kuehn, Hye Sun
Kuffa, Peter
S10-05Kuga, Taiga
WS08-03-P○WS22-12-P
WS29-22-P
Kuhns, Michael S. WS26-18-P
Kumagai, Shogo
WS27-26-P
Kumamoto, Yosuke WS20-15-O/P
Kumanogoh, Atsushi WS14-06-O/P
WS15-01-O/P

WS15-04-O/P
WS17-14-P
WS18-06-O/P
WS24-18-P
WS30-19-O/P
WS11-15-P
WS04-16-O/P
WS09-09-O/P
WS19-02-O/P
WS21-06-O/P
WS23-09-O/P

Kume, Kyo
Kume, Yasuharu

Kunimura, Kazufumi○WS09-08-O/P
WS17-15-P
WS25-16-O/P
Kunisawa, Jun
WS09-07-O/P
WS13-13-O/P
WS19-03-O/P
WS30-03-O/P
Kunitake, Shinji
WS16-15-O/P
Kuno, Hitoshi
WS26-15-P
Kuno, Yoshihiro
WS05-10-P
Kunugi, Shinobu
WS29-14-O/P
Kurachi, Makoto
WS22-07-O/P
Kurane, Tomomi
WS03-05-O/P
Kurasawa, Kazuhiro WS09-19-P
Kurasawa, Mitsue
WS06-14-P○WS03-03-O/P
Kuratani, Ayumi
Kurihara, Shunjirou ○WS21-17-P
Kuroda, Etsushi
WS03-17-P
WS07-15-O/P
WS18-10-P
WS21-03-O/P
Kuroki, Kimiko
WS24-09-O/P
Kurosaki, Masayuki WS23-13-O/P
Kurosaki, Tomohiro S07-01
WS08-07-O/P
WS08-20-O/P
WS12-05-P○WS03-26-P
Kurosu, Takeshi
Kurosugi, Akane
WS12-07-O/P
Kurotaki, Daisuke
WS27-17-P○T03-01
Kusano, Seisuke
WS26-21-P
Kusaoi, Makio
WS22-12-P
WS29-22-P○WS13-03-O/P
Kusuda, Takeshi
Kusumoto, Yutaka
WS21-18-P
Kusunoki, Susumu WS06-03-O/P
Kusunoki, Yoichiro WS23-14-P
Kutlu, Burak
WS02-02-O/P
Kutsuna, Satoshi ○OT01
Kuwabara, Taku
WS10-18-P
WS31-15-P○WS26-14-P
Kuwahara, Motoi
WS06-03-O/P○WS28-10-P
Kuwata, Takeo
Kuze, Yuta
WS27-23-O/P
Kwon, Yong-Jin
WS02-25-P
Kyoizumi, Seishi
WS26-23-P
Kuninaka, Yumi

L
Laidlaw, Brian
Lantz, Olivier
Lanz, Tobias V.
Le, Toan○S07-02
WS03-06-O/P○S11-05
WS10-07-O/P

Lee, HyunseungWS02-25-P
Lee, Jiyeon
WS29-08-P
Lee, Mark S.
WS26-18-P
Lee, Michelle S.J.
WS27-18-P
Lee, Michelle Sj
WS28-24-P
Lee, Michelle Sue Jann
○WS03-02-O/P
WS07-12-P
WS12-18-O/P
Lee, Songhee
WS02-25-P
Lee, Yoonha
WS07-08-P
Leedham, Simon
WS02-07-O/P
Legoux, Francois
WS03-06-O/P
Leidner, Rom S
WS02-17-P
Lenardo, Michael
S06-03○WS07-11-P
Li, Bo○WS01-06-O/P
Li, Jing
WS01-15-P
WS07-05-O/P
WS18-14-P
WS18-20-P
Li, Nanjun
WS11-22-P
Li, Xiao-Kang
WS02-05-P○WS27-27-P
Li, Xiaoyun
Li, Yifan
WS03-04-O/P
Li, Yuhua
WS22-03-O/P
Lian, Benedict Shi Xiang
WS29-02-O/P
Liang, Hong-Erh
WS05-06-O/P
Liao, Hung-Chun
WS28-17-P○S08-02
Liesz, Arthur○WS02-28-P
Lin, Chih-Yu
Lin, Yi-Tzu
WS27-26-P○WS16-08-O/P
Lin, Youwei○WS18-08-O/P
Liu, Guohao
Liu, Kaiwen
WS29-11-O/P○WS07-03-O/P
Liu, Qizhi
Liu, Saisai
WS08-09-O/P○WS28-17-P
Liu, Shih-Jen○WS28-02-O/P
Liu, Yafei○WS13-13-O/P
Liu, Zilai
WS30-03-O/P
Llamas Covarrubias, Mara
WS28-05-O/P○WS25-04-O/P
Lo, Pei-Chi
Locasale, Jason
WS27-27-P○WS16-15-O/P
Long, Wang
Lopez-Mejia, Isabel
WS27-27-P○S12-05
Lowe, Scott○S11-04
Lu, Xiuyuan
WS10-10-P
WS26-22-P
WS28-12-P○S16-04
Lucas, Carolina
Luginguhehl, Joachim
WS22-04-O/P○WS02-26-P
Lyu, Xiabing
WS10-07-O/P
WS31-04-O/P

M
M Locksley, Richard WS05-06-O/P
M. Refaat, Ahmed ○WS08-10-O/P○WS20-08-P
Ma, Shuhe
Macalinao, Maria Lourdes

WS10-04-O/P
Machida, Kentaro
WS21-14-P
Machiyama, Hiroaki WS11-21-P○WS26-06-O/P
WS26-10-P○S07-04
Mackay, Laura
Maeda, Keiko
WS23-09-O/P○WS17-04-P
Maeda, Kengo
Maeda, Munetoshi WS11-15-P○WS18-17-P
Maeda, Reina○WS15-16-P
Maeda, Shinji
WS23-07-P
WS26-19-P
Maeda, Takuya
WS02-02-O/P
Maeda, Tomoyo
WS15-16-P
WS23-07-P
Maeda, Yohei
WS23-10-O/P
Maehara, Akie
WS04-16-O/P
WS21-06-O/P○WS24-05-O/P
Maehara, Yui
Maekawa, Naoya
WS03-09-O/P
Maekawa, Toshio
WS07-01-O/P○WS25-03-O/P
Maekawa, Yoichi
WS12-17-P
WS18-13-P
Maenaka, Katsumi WS24-09-O/P
WS30-04-P
Maenohara, Yuji
WS15-08-O/P
Maeoka, Ryosuke
WS05-22-P
Maharani, Aprilia ○WS27-04-P
Mahendran, Yuvaraj WS12-03-P
Makiuchi, Nana
WS29-13-P
Makusheva, Yulia
WS06-12-P
Malissen, Bernard WS26-01-O/P○WS06-06-O/P
Mallahalli, Manu
WS06-06-O/P
Mamonkin, Maksim WS26-06-O/P
Mandai, Masaki
WS11-23-O/P
WS29-20-P
Maruhashi, Takumi WS24-01-O/P
WS24-06-P○WS24-07-P
Maruyama, Mitsuo WS08-17-P
Maruyama, Naoki
WS31-09-P
Maruyama, Takeshi WS02-24-P
Maruyama, Toshiaki WS23-09-O/P
Masaki, Katsunori WS05-19-P
Mashima, Tetsuo
WS27-03-P
Massilamany, Chandirasegaran
WS16-08-O/P
Masuda, Takahiro
S08-04
Masuoka, Hiroaki
WS06-04-O/P
Masuta, Yuji
WS10-05-O/P○WS12-08-P
WS28-08-O/P
Masutani, Yurie
WS09-06-O/P
Masuyama, Satoshi ○WS10-20-P
Matoba, Takuma
WS16-13-P
Matozaki, Takashi
WS04-01-O/P
WS20-13-P
Matsuba, Shintaro ○WS20-14-P
Matsubara, Tsukasa WS15-03-O/P
Matsuda, Akira
WS19-02-O/P
Matsuda, Hiroshi
S09-03
Matsuda, Kenshiro WS10-02-O/P
Matsuda, Kosuke
WS09-20-P
Matsuda, Masashi WS11-07-O/P
Matsuda, Masaya ○WS21-10-P

202

Matsuda, Ryosuke
Matsuda, Satoshi
Matsuda, Tadashi

WS05-22-P
WS18-13-P
WS17-01-O/P
WS17-02-P
Matsuda, Yasuyuki ○WS29-09-P
Matsufuji, Hiroshi
WS19-06-P
Matsui, Ako
WS10-25-P○WS16-12-O/P
WS31-20-P
Matsui, Hidehito
WS03-10-P
Matsui, Katsuhiko ○WS09-13-P
Matsui, Makoto
WS27-02-P○WS06-17-P
Matsui, Miki
WS27-12-P
Matsui, Takeshi
WS09-01-O/P
Matsukawa, Akihiro WS02-22-P
Matsumoto, Hisatake WS23-15-P
Matsumoto, Isao
WS15-10-P
WS15-11-P
WS15-17-P
WS15-20-P
WS18-25-P○C01-01
Matsumoto, Kaho
WS28-10-P
Matsumoto, Ken
WS27-14-O/P
Matsumoto, Kenji
S09-02
Matsumoto, Koichiro WS21-12-P
Matsumoto, Kotaro WS10-15-P
Matsumoto, Masanori WS08-07-O/P
Matsumoto, Minoru WS16-19-P
Matsumoto, Mitsuru ○S05-02
WS16-19-P
Matsumoto, Ryohtaroh○WS19-14-O/P
Matsumoto, Satoru WS02-16-P○WS02-18-P
Matsumoto, Takehisa WS28-09-P
Matsumoto, Takumi WS15-08-O/P
Matsumoto, Yoshihiro WS06-14-P
Matsumura, Kana
WS13-10-O/P
Matsumura, Kazunori○WS12-13-P
Matsumura, Ryutato WS04-05-P
Matsumura, Takayuki WS12-02-P
Matsunaga, Himawari○WS19-17-P
Matsune, Shoji
WS19-07-P
Matsuno, Yoshihiro WS19-10-P○WS01-20-P
Matsuo, Kana
WS06-15-P
Matsuo, Kazuhiko
WS04-09-P
WS25-01-P
WS25-07-P○WS27-05-P○WS25-15-O/P
Matsuo, Soichi
Matsuo-Dapaah, Julia
WS03-02-O/P
WS07-12-P○WS12-18-O/P
Matsuoka, Shuji
WS11-24-P
WS31-09-P
Matsusaka, Masako WS05-19-P
Matsushima, Kouji WS02-01-P
WS10-06-O/P
WS14-15-O/P
WS18-24-P
WS29-14-O/P
Matsushima, Miyoko WS09-10-P

WS09-15-P
WS24-14-P
WS29-03-P
WS29-04-P
Matsushita, Kazufumi WS03-17-P
WS07-15-O/P
WS21-03-O/P
Matsushita, Sho
WS25-05-O/P
Matsushita, Shuzo WS28-10-P
Matsuyama, Hiromi WS21-14-P
Matsuyama, Nobuhiro
WS03-19-P
Matsuyama, Shimpei WS26-12-P
Matsuyama, Takahiro WS21-14-P
Matsuzaka, Yu
WS29-20-P
Matsuzaki, Goro
WS03-05-O/P
WS12-14-P
Matsuzawa, Moe
WS09-09-O/P
WS19-02-O/P
Matuda, Miho
WS07-13-P
Matuda, Tadashi
WS08-06-P
Medzhidov, Nazim WS13-10-O/P
Meguro, Kazuyuki ○S06-03
WS05-15-P
WS18-12-P
WS21-17-P
Meng, Ryan
WS02-17-P○T08-01
Middlebrook, A
Mikami, Norihisa
WS16-04-O/P
Mikami, Tetsuo
WS07-22-P
Mikami, Tetuo
WS19-04-P○OT04
Mikami, Yohei
WS05-09-P
WS18-15-P
WS22-24-P○C03-01
Mikulski, Zbigniew WS19-13-O/P
Minami, Shohei
WS10-05-O/P
Minamiguchi, Sachiko
WS11-23-O/P
Minamikawa, Natsuki WS20-11-P
WS20-12-P
Minamitani, Takeharu WS28-15-P○WS15-12-P
Minegishi, Emi
Mino, Nanami
S02-04
Minoda, Aki
WS07-16-O/P
Minoda, Akiko
WS05-17-O/P
WS05-20-P
Minohara, Kiyoshi ○WS16-13-P○WS02-20-O/P
Misawa, Aya
Misawa, Takuma ○WS07-07-O/P
Mise-Omata, Setsuko○WS02-03-O/P
WS11-03-P
WS28-11-P
Misumi, Munechika WS23-14-P
Mita, Hironobu
WS18-05-O/P
Mita, Yukiyoshi
WS02-04-O/P
Mitsuhashi, Keigo
WS28-16-P
Mitsuyama, Yumi
WS23-15-P
Miura, Noriko
WS30-12-P
Miura, Yuji
WS11-14-O/P
Miyagawa, Satoshi WS12-10-P
Miyagi, Yohei
WS27-24-O/P
Miyahara, Yoshihiro WS11-26-P○T01-02○WS09-05-O/P
Miyai, Tomohiro
WS22-13-P
Miyajima, Atsushi
WS17-15-P

Miyajima, Michio ○S15-04○WS22-13-P
Miyajima, Yurina
Miyakawa, Satomi WS17-13-O/P
Miyake, Kensuke
WS02-27-O/P
WS04-06-O/P○WS07-17-O/P
WS09-11-P
WS14-09-O/P
WS20-02-O/P
WS21-08-O/P
WS29-11-O/P
WS30-20-P
Miyake, Minoru
WS29-23-P
Miyake, Sachiko
WS06-02-O/P
WS08-03-P
WS09-11-P
WS16-08-O/P
WS17-11-O/P
WS21-11-P
WS22-12-P○WS06-14-P
Miyake, Shota
Miyake, Yasunobu ○WS12-20-O/P
Miyake, Sachiko
WS21-20-P
Miyamoto, Kentaro WS18-15-P
WS19-12-O/P
Miyamoto, Masahiko WS12-21-P
Miyamoto, Sho
WS12-06-O/P
Miyamoto, Yu
S08-03○WS16-16-P
Miyata, Hiroko
WS15-14-P
Miyata, Jun
WS05-19-P
Miyatake, Shoichiro ○WS07-18-P○WS13-07-O/P
Miyatake, Yuji
Miyauchi, Kosuke
WS08-01-O/P
Miyauchi, Kouske
WS28-09-P
Miyawaki, Atsushi ○E01
Miyazaki, Hirofumi WS04-11-O/P○WS20-07-P
Miyazaki, Hiromi
WS20-16-P
Miyazaki, Kazuko
WS01-10-P○WS01-11-P
WS13-08-P
WS28-13-P
Miyazaki, Masaki ○S13-02
WS01-10-P
WS01-11-P
WS13-08-P
WS22-16-P
WS28-13-P
Miyazaki, Yoshiyuki ○WS14-12-P
Miyazaki, Yumi
WS15-03-O/P
Miyazaki, Yusuke
WS15-14-P
Miyazawa, Kenji
WS19-06-P
Miyazawa, Masaaki WS08-05-P
WS15-03-O/P
Miyoshi, Shion
WS24-13-P
Mizobuchi, Masaaki WS13-09-P
Mizoguchi, Atsushi ○C06-02
Mizoguchi, Izuru
WS17-13-O/P
Mizui, Masayuki
WS10-20-P
Mizukami, Shusaku WS12-10-P
Mizuno, Seiya
S09-03
Mizuno, Tetsushi
WS28-16-P○WS13-15-P
Mizunoe, Yuhei
WS22-05-O/P
WS22-21-P
Mogami, Haruta
WS29-20-P
Mogawa, Hiroki
WS13-09-P

Mohanty, Subhasis WS18-25-P
Momozawa, Yukihide WS11-08-P○WS11-13-P
Moniwa, Keigo○WS26-01-O/P
Mori, Daiki
Mori, Kazuma
WS04-19-P
WS14-04-P
WS29-19-P
Mori, Kenichiro
WS29-09-P
Mori, Moeka
WS28-18-P
Mori, Shotaro
WS05-01-O/P
WS10-10-P
Mori, Takeshi
WS16-07-O/P
Mori, Takuya
WS14-05-P
Mori, Tatsunori
WS03-25-P
Mori, Toshio
WS27-01-P
Moriguchi, Kota
WS06-03-O/P
Morii, Kenji
WS27-10-O/P
Morikawa, Yoshihiro WS17-15-P○WS09-01-O/P
Morimoto, Ari
Morimoto, Chikao
WS15-19-P
Morimoto, Junko ○WS16-19-P
Morimoto, Motoko ○WS03-18-P○OT13
Morimoto, Ryo○S13-01
Morimoto, Takayuki WS05-22-P
Morinobu, Akio
WS15-09-O/P
WS25-09-O/P
WS31-07-O/P
Mori-Saitoh, Yoshiko WS04-06-O/P
Morishima, Tatsuya WS22-03-O/P
WS23-04-O/P
Morita, Akimichi
WS16-13-P
Morita, Daisuke
WS26-05-O/P○WS26-17-P○S09-02
Morita, Hideaki
Morita, Masashi
WS10-20-P
Morita, Masashi
WS17-03-O/P
WS18-17-P
WS26-02-O/P
WS26-11-P
WS26-12-P○WS08-13-O/P
Morita, Naoki
Morita, Rimpei
WS04-13-O/P
WS19-07-P
WS24-15-O/P
WS29-06-O/P
WS29-07-P
WS29-08-P
WS30-01-P
WS27-19-P
Morito, Naoki
WS29-18-P
Moriwaki, Kenta
WS24-13-P
Moriyama, Mizuki
WS20-03-P○S01-04
Moriyama, Saya
WS12-02-P
WS12-08-P
WS12-05-P
Moro, Kazuyo
WS05-07-O/P
WS05-08-P
WS05-17-O/P
WS05-19-P
WS07-16-O/P
WS19-03-O/P
WS21-19-P
WS23-10-O/P
WS25-04-O/P
WS31-02-O/P
Moroishi, Toshiro
WS08-09-O/P

203

Motohashi, Shinichiro WS02-04-O/P
WS02-08-O/P
WS02-09-P
WS02-10-P
Motomura, Kaori
WS07-22-P
Motomura, Yasutaka
WS19-03-O/P○WS23-10-O/P
WS25-04-O/P
WS31-02-O/P○A02-02
Motooka, Daisuke
WS06-21-P
Motoshima, Takanobu
WS11-14-O/P
Motoyama, Satoru WS27-23-O/P
Motozono, Chihiro ○WS28-03-O/P
WS10-08-P
Moudgil, Tarsem L. WS02-17-P○WS08-11-O/P
Mtali, Yohana
WS30-07-O/P
Mueller, James L.
WS13-01-O/P○WS07-15-O/P
Mukai, Amane
Mukai, Yohei
WS15-03-O/P
Mukaida, Naofumi WS22-07-O/P
WS25-16-O/P
Mukoyama, Hiroki ○WS25-09-O/P
Mulatsih, Sri
WS11-25-P
Muna Al-Habsi, Muna S12-01○C12-02
Munitz, Ariel
Muraguchi, Atsushi WS26-09-O/P
WS26-21-P
Murakami, Akikazu WS13-18-P
Murakami, Akira
WS09-09-O/P
WS19-02-O/P
Murakami, Hiromoto WS28-12-P
Murakami, Hirotomo WS10-09-P
WS23-13-O/P
Murakami, Makoto WS14-14-O/P
Murakami, Mari
WS07-06-O/P
Murakami, Masaaki WS03-26-P
WS15-05-O/P
WS17-06-O/P
WS19-10-P
WS31-12-P
Murakami, Ryuichi WS16-01-O/P
WS16-03-P
Murakami, Takashi WS02-12-P
WS27-09-P
Murakami, Yusuke ○WS21-15-P
Murakawa, Yasuhiro WS23-01-O/P
WS23-03-O/P
Muraki, Yasushi
WS07-21-P
Murasawa-Tomizawa, Mariko
WS11-07-O/P
Murata, Akihiko
WS08-21-O/P○WS10-01-O/P○WS10-02-O/P
Murata, Rikito
Murata, Shiro
WS03-09-O/P
Murata, Yoji
WS04-01-O/P
WS20-13-P
Murayama, Aiki
WS04-15-P
Murayama, Goh
WS08-03-P
WS29-22-P
Murayama, Gou
WS22-12-P
Muro, Ryunosuke
S01-04○WS01-04-O/P
Muro, Shigeo
WS11-19-P
Muroi, Sawako
WS01-02-O/P

Muto, Akihiko○WS08-08-P

N
Nabe, Takeshi
WS21-10-P
Nabekura, Tsukasa WS05-05-O/P
WS25-15-O/P
WS05-03-O/P
Nagae, Masamichi WS05-01-O/P○WS10-10-P
Nagahara, Akihito
WS31-09-P
Nagahata, Yosuke ○WS22-02-O/P
WS22-14-P
WS31-17-P
Nagai, Hodaka
WS26-02-O/P○WS26-12-P
WS26-11-P
Nagai, Shigenori
WS10-19-P○WS16-17-P
Nagai, Yoshinori
WS14-11-O/P
WS29-13-P
WS30-17-P
Nagaishi, Takashi ○WS19-19-O/P
Nagaki, Yushi
WS27-23-O/P○WS01-21-P
Nagano, Sano
WS06-15-P○WS26-08-O/P
Nagano, Seiji
Naganuma, Makoto WS01-18-P
Nagao, Jun-Ichi
WS03-14-P
WS03-16-P○WS03-23-P
WS12-15-P
Nagao, Kei
WS09-11-P○WS17-11-O/P
WS21-20-P
Nagaoka, Hitoshi
WS08-04-P
Nagasaki, Joji
WS27-06-P
Nagasawa, Takashi WS17-14-P
WS22-08-O/P
Nagase, Hiroshi
WS21-07-O/P
Nagashima, Mikako ○WS14-08-P
WS22-11-P
Nagashima, Ryuichi ○WS05-10-P
Nagata, Kazuki
WS04-07-P
WS09-16-P
WS20-10-O/P
WS20-11-P
WS20-12-P
WS21-05-O/P○WS21-07-O/P○WS06-20-P
Nagata, Keiko
Nagata, Makoto
WS25-05-O/P
Nagata, Noriyuki
WS19-10-P
Nagata, Ritsu
WS05-18-O/P○WS05-20-P
Nagata, Satoshi
WS18-18-P
WS31-16-P
Nagatake, Takahiro WS09-07-O/P
WS13-13-O/P
WS30-03-O/P
Nagato, Toshihiro
WS27-20-O/P○WS10-09-P
Nagatsuka, Yuta
Nagayasu, Atsushi WS15-14-P
Nagira, Daiki
WS15-04-O/P○WS31-07-O/P
Naito, Ryota
Naito, Taku
WS10-18-P
WS26-14-P

WS31-15-P
Nakabayashi, Jun
WS07-17-O/P
Nakagawa, Ichiro
WS05-22-P○WS11-08-P
Nakagawa, Ryo
Nakagawa, Tomoya WS22-12-P
WS04-15-P
Nakagawa, Youki
WS31-08-O/P
Nakagawara, Kensuke ○WS11-03-P
Nakagome, Kazuyuki○WS25-05-O/P
Nakahama, Taisuke ○WS30-10-P
Nakahata, Nana
WS03-07-O/P
Nakahira, Masakiyo ○WS18-10-P
Nakai, Akiko
WS13-04-O/P○WS17-10-O/P
Nakai, Wataru
WS03-12-P
WS28-02-O/P○WS31-05-O/P
WS31-07-O/P
Nakajima, Akira
WS16-03-P
WS26-04-O/P
Nakajima, Hiroshi ○S14-05
WS04-05-P
WS18-12-P
WS21-17-P
WS05-15-P
Nakajima, Shihori
WS22-19-P
Nakajima, Takahiro ○WS18-21-P
WS26-07-O/P
Nakajima, Yuka
WS24-02-O/P
Nakamae, Hirohisa WS27-06-P
Nakamae, Sayuri ○WS12-10-P
Nakamizo, Satoshi ○S11-02
WS10-13-P
Nakamoto, Nobuhiro WS13-05-O/P
WS18-15-P
WS24-17-O/P
Nakamoto, Shun
WS28-25-P○WS14-14-O/P
Nakamura, Akari
Nakamura, Akihiro WS02-12-P
WS27-09-P
Nakamura, Akira
WS28-23-P
Nakamura, Kenta
WS02-20-O/P
Nakamura, Kiminori WS19-11-P
Nakamura, Kiwamu WS14-07-P
Nakamura, Koutarou○WS17-12-O/P
Nakamura, Mitsutoshi
WS05-22-P
Nakamura, Yamami WS16-04-O/P
Nakamura, Yumina WS06-03-O/P
Nakamura, Yutaka WS28-06-O/P
Nakanishi, Makoto ○S12-02○E07
Nakanishi, Yusuke WS19-06-P
Nakano, Hayato
WS14-12-P
Nakano, Hiroyasu
WS19-04-P
WS24-13-P
Nakano, Kohei
WS18-18-P
Nakano, Manabu ○WS21-16-P
Nakano, Masahiro WS23-03-O/P
Nakano, Nobuhiro WS04-16-O/P
WS09-09-O/P○WS09-17-P
WS20-11-P
WS21-06-O/P
WS23-09-O/P
Nakano, Shiori
WS06-09-P

Nakao, Mitsuyoshi WS29-24-P
Nakase, Hiroyuki
WS05-22-P
Nakashima, Chisa WS25-06-O/P
Nakashima, Hiroyuki WS04-19-P
WS14-04-P○WS20-16-P
WS29-19-P
Nakashima, Masahiro
WS04-19-P
WS14-04-P
WS20-16-P
WS29-19-P○WS27-06-P
Nakashima, Yasuhiro
Nakata, Mikiyo
WS08-10-O/P
Nakato, Gaku
WS22-03-O/P
Nakatsukasa, Hiroko WS16-11-P○WS18-02-O/P
Nakayama, Maiko
WS29-15-O/P
Nakayama, Misako ○WS12-09-P
WS29-21-P
Nakayama, Takashi WS04-09-P
WS25-01-P
WS25-07-P
WS27-05-P
Nakayama, Toshinori WS02-04-O/P
WS12-07-O/P
WS21-13-P
Nakayamada, Shingo WS15-14-P
WS31-06-O/P
Nakazawa, Tsutomu○WS05-22-P
Nameta, Masaaki
WS12-21-P
Namiki, Takeshi
WS04-03-O/P
Naniwa, Taio
WS15-16-P
WS23-07-P
WS26-19-P
Nanki, Toshihiro
WS07-22-P
Nanri, Yasuhiro
WS09-20-P
Nara, Taketoshi
WS11-16-P
Narazaki, Taisuke ○WS24-06-P
Narita, Shintaro
WS11-16-P
Narita, Tomoya
WS21-15-P
Naruo, Munehiro ○WS30-01-P
Nasti, Alessandro ○WS11-15-P
Nasu, Ryo
WS01-13-P
WS01-16-P○WS02-04-O/P○WS30-15-P
Negishi, Hideo○WS16-10-P
Negishi, Naoko
Negishi, Yasuyuki ○WS04-13-O/P
WS24-15-O/P
WS30-01-P
Negishi, Hideo
WS28-24-P
Negoro-Yasumatsu, Kanae
WS03-14-P
WS03-23-P
WS12-15-P
Nemoto, Masahiro WS12-07-O/P
Nguyen, Thanh Cong WS12-09-P
Nguyen, Cong Thanh○WS29-21-P
Niewczas, Monika A. WS26-18-P○WS08-14-O/P
Nihei, Yoshihito
WS08-15-P
Niimi, Akio
WS15-16-P
WS23-07-P
WS26-19-P
Niimura, Mayumi
WS08-09-O/P
Niiro, Hiroaki
WS23-08-O/P

204

Niitsu, Takatoshi
Nishida, Mikako
Nishida, Shogo
Nishigai, Yuki

WS14-05-P
WS18-23-P
WS16-11-P
WS04-10-P
WS04-18-P
Nishihama, Kota
WS06-18-P
WS25-13-O/P
WS25-14-P
Nishijima, Hitoshi
WS11-21-P
WS26-06-O/P
WS26-10-P
Nishikata, Takahito WS30-09-P
Nishikawa, Hiroyoshi WS11-05-O/P
WS27-26-P
Nishikimi, Akihiko
WS08-17-P
Nishikomori, Ryuta WS29-10-O/P
Nishimura, Fumihiko WS05-22-P
Nishimura, Taichi
WS20-13-P
Nishimura, Tasuku ○WS12-23-O/P
Nishimura, Tomoya WS14-05-P○WS31-17-P
Nishimura, Yuji
Nishina, Takashi
WS19-04-P
Nishino, Teppei
WS29-18-P○WS07-22-P
Nishio, Junko○WS06-19-P
Nishio, Yoshiaki
Nishioka, Tatsuki ○WS11-19-P○WS29-22-P
Nishioka, Yujin
Nishiyama, Akira
WS22-15-P
Nishiyama, Chiharu WS04-07-P
WS09-16-P
WS20-10-O/P
WS20-11-P
WS20-12-P
WS21-05-O/P
WS21-07-O/P
WS22-05-O/P
WS22-21-P
Nishiyama, Mitsuru WS31-08-O/P
Nishiyama, Nobuhiro WS27-02-P
Nishiyama, Taihei
WS15-10-P
WS15-20-P
Nishiyama, Yasuhiro WS19-07-P○S02-04
Nitta, Takeshi
WS01-04-O/P
Nochi, Tomonori
WS19-20-O/P
Noda, Takehiro
WS10-09-P
Node, Eri
WS09-07-O/P
Nogami, Keiji
WS23-06-P
Nogimori, Takuto ○WS10-05-O/P
WS10-09-P
WS12-08-P
WS23-13-O/P
WS28-08-O/P
WS28-19-P
Noguchi, Emiko
S09-03
Noguchi, Kouji
WS08-01-O/P
Noguchi, Natoto
WS07-14-P
Noh, Kumhee
WS02-25-P
Nomoto, Takahiro
WS27-02-P
Nomoto, Yusuke
WS09-12-P
WS25-06-O/P
Nomura, Ena
WS19-12-O/P
Nomura, Hisashi
WS06-01-O/P
Nomura, Norimichi S12-01
WS27-14-O/P○WS20-09-O/P
Nonaka, Daichi
Nosaka, Mizuho
WS17-15-P○WS25-16-O/P

Noto, Daisuke
WS06-02-O/P
Nouari, Hocine
WS12-01-P
Numakura, Kazuyuki WS11-16-P○S10-05
Nunez, Gabriel
Nuñez, Gabriel
WS12-24-P
Núñez, Gabriel
S10-01
Nunomura, Satoshi ○WS09-20-P

O
Oba, Seiya
WS12-06-O/P
Obata-Ninomiya, Kazushige○WS18-07-O/P○WS08-19-O/P
Ochiai, Kyoko
Ochiai, Sotaro
S14-02
WS09-05-O/P○WS23-06-P
Oda, Akihisa○S06-01
Oda, Hirotsugu
Oda, Maori
WS16-01-O/P
Odagiri, Takashi
WS07-21-P
Odanaka, Mizuyu
WS16-13-P
Ogasawara, Kazumasa WS12-09-P
Ogasawara, Kouetsu WS04-04-O/P
Ogata, Kosuke
WS19-14-O/P
Ogawa, Aimi
WS21-12-P○WS01-02-O/P
Ogawa, Chihiro
Ogawa, Hideoki
WS09-17-P
Ogawa, Jun
WS04-07-P
Ogawa, Koki
WS12-10-P○S03-03
Ogawa, Mikako
Ogawa, Norihiko
WS11-15-P
Ogawa, Ryohei
WS28-16-P
Ogawa, Shuhei
WS09-02-O/P
Ogawa, Takasuke
WS09-06-O/P
Ogawa, Tomohiro
WS21-12-P
Ogawara, Sayaka
WS26-12-P
Ogiwara, Haru
WS02-01-P○WS23-01-O/P
Oguchi, Akiko
WS23-03-O/P○WS28-12-P
Ogura, Hideki
Ogura, Hiroshi
WS23-15-P
Ogura, ToshihikoS12-01
WS27-04-P
WS27-14-O/P○WS07-08-P
Ohara, Daiya
WS15-09-O/P
WS25-09-O/P
Ohara, Moeko
WS09-10-P○WS09-15-P
WS24-14-P
WS29-03-P
WS29-04-P
Ohara, Osamu
WS06-01-O/P
Ohara, Toshiaki
WS02-22-P
Ohashi, Kazuhiko
WS03-09-O/P
Ohashi, Mihoko
WS18-11-P
WS25-08-P
Ohashi, Wakana ○WS20-04-O/P
Oh-Hora, Masatsugu○WS29-15-O/P○WS19-11-P
Ohira, Shuya
Ohira, Yuta
WS27-18-P○WS16-11-P
Ohishi, Kanae
Ohishi, Waka
WS23-14-P
WS26-23-P
Ohkawa, Yasuyuki WS08-18-P
Ohki, Kokoro
WS01-20-P

Ohki, Shun

WS20-03-P
WS28-18-P
Ohkura, Iori
WS31-16-P
Ohkura, Naganari
WS16-13-P○WS13-17-O/P
Ohkusa, Hinako
Ohmomo, Hideki
WS06-09-P
Ohmura, Koichiro
WS31-07-O/P
Ohnishi, Reiko
WS26-04-O/P○S16-05
Ohno, Hiroshi
WS05-18-O/P
WS05-20-P
WS12-19-P
WS19-14-O/P
WS19-18-O/P
Ohno, Mai
WS26-04-O/P○WS10-14-P
Ohno, Yusuke
WS26-15-P○WS05-14-O/P
Oh-Oka, Kyoko
Ohshima, Shino
WS26-15-P○WS18-18-P
Ohta, Akio
WS24-03-P
WS31-16-P
Ohta, Etsuro
WS04-10-P
WS04-18-P
Ohta, Hiroshi
WS19-10-P○S03-02
Ohta, Seiichi
Ohta, Shigeki
WS02-20-O/P
WS27-10-O/P
Ohteki, Toshiaki
S13-05
WS04-03-O/P
WS05-11-O/P
Ohya, Susumu
WS06-17-P○WS27-12-P○WS10-23-P
Ohyagi, Masaki
Ohyama, Ayako
WS15-10-P○WS15-20-P
C01-01
Oike, Yuichi
WS30-04-P
Oishi, Eiji
WS03-09-O/P○WS19-23-P
Okada, Hiraku
Okada, Masahiro ○WS11-18-P
Okada, Naoki
WS27-20-O/P
Okada, Takaharu ○S14-02
WS07-19-P
WS09-05-O/P
Okada, Takayuki
WS10-17-P○WS06-15-P
Okada, Wataru
Okagawa, Tomohiro WS03-09-O/P
Okajima, Akira
WS27-07-P
Okamoto, Isamu
WS21-12-P
Okamoto, Kazuo
WS29-17-P
Okamoto, Masaaki ○WS06-13-P
Okamoto, Nanako WS22-05-O/P○WS22-21-P
Okamoto, Ryuichi
WS19-19-O/P
Okamoto, Toru
WS28-13-P
Okamura, Tomohisa WS13-03-O/P
WS15-08-O/P
WS25-12-O/P
Okamura, Tomotaka WS28-04-O/P
WS28-08-O/P
Okano, Hideyuki
WS04-10-P○WS03-01-O/P
Okano, Tokuju
WS14-02-P
Okano, Yuko
WS06-18-P○WS25-13-O/P
WS25-14-P
Okayama, Toshitugu WS08-02-P

Okazaki, Il-Mi

WS24-01-O/P
WS24-06-P
WS24-07-P
Okazaki, Ken
WS30-01-P
Okazaki, Shogo
WS13-15-P
WS22-05-O/P
WS22-21-P
Okazaki, Taku
WS24-01-O/P
WS24-06-P
WS24-07-P
Okazaki, Tomohiko WS12-11-P
Okazawa, Hitoshi ○S10-04
Oki, Shinji
WS06-06-O/P
WS10-03-O/P
WS10-24-P
Okoshi, Momoko
WS02-08-O/P
Okuda, Hiroshi
WS27-17-P
Okuda, Takahisa
WS30-01-P○WS11-09-O/P
Okuma, Atsushi
Okumura, Cj
WS23-09-O/P
Okumura, Ko
WS04-16-O/P
WS09-06-O/P
WS09-09-O/P
WS09-17-P
WS15-19-P
WS19-02-O/P
WS21-06-O/P
WS23-09-O/P
WS24-05-O/P
WS31-09-P
Okumura, Ryu
WS07-03-O/P
WS12-25-P
WS19-01-O/P
Okuno, Tatsusada WS10-20-P
Okuno, Toshiaki
WS29-15-O/P
WS29-24-P
Okunura, Ko
WS16-10-P
Okura, Hiroko
WS02-08-O/P
Okuwa, Takako
WS12-21-P
Okuyama, Kazuki ○S06-05
WS01-02-O/P
WS23-02-O/P
Okuyama, Ryuhei
WS02-20-O/P
Okuyama, Yuko
WS01-06-O/P
WS01-15-P
WS07-05-O/P
WS10-21-P
WS18-14-P
WS18-20-P
WS26-11-P○WS27-07-P
Okuzaki, Daisuke
WS03-26-P
Omata, Yasunori
WS15-08-O/P○S02-05
Omatsu, Yoshiki○WS22-08-O/P
Omori-Miyake, Miyuki○WS09-03-O/P
Omura, Seiichi
WS06-03-O/P
WS31-14-P
Onai, Nobuyuki
WS20-14-P○S15-03
O'Neill, Luke
Ong, Guang Han
WS14-10-P
Onishi, Shintaro
WS14-05-P○WS24-12-P
Ono, Chisato
Ono, Sachiko
WS07-20-P
Ono, Takehito
WS29-17-P○WS03-15-P
Ono, Takeshi
Ono, Yuko
WS03-22-P

205

Onodera, Atsushi
Onodera, Kana

WS21-13-P
WS04-10-P
WS04-18-P
Onodera, Taishi
WS12-02-P○WS12-05-P○WS10-12-P
Onohara, Emi
Onomoto, Koji
WS30-11-P
Onoue, Kousuke
WS31-08-O/P
Onoue, Miki
WS12-07-O/P
Onuki, Masayoshi
WS20-04-O/P
Oowa, Chizuru
WS05-02-P○WS05-12-P○WS14-10-P
Ori, Daisuke
WS22-16-P
WS29-01-O/P
WS29-02-O/P
Oritani, Kenji
WS08-06-P
WS17-01-O/P
WS17-02-P○WS24-04-P
Osaki, Yoshiro
Osari, Suguru
T09-02
Osawa, Hiroaki
WS28-16-P○S14-01
O'shea, John
Oshima, Naoki
WS04-19-P
WS14-04-P
Oshiro, Yuya
WS18-18-P
Oshiumi, Hiroyuki
WS08-11-O/P
WS11-14-O/P
WS12-22-P
WS12-23-O/P
WS19-05-P
WS21-09-O/P
WS30-07-O/P
Ota, Yasunori
WS04-06-O/P
Otake-Kasamoto, Yuriko
S16-03
Otaki, Aika
WS13-15-P
WS22-05-O/P○WS24-16-P
Otani, Kento
Otobe, Yuta
WS30-11-P
Otomo, Kotaro
WS15-12-P○WS28-15-P
Otsubo, Ryota
Otsuka, Haruna
WS15-19-P
Otsuka, Kunihiro
WS04-08-O/P○WS15-06-O/P
WS15-07-O/P
WS15-18-P
WS31-10-P
Otsuka-Yamasaki, Yayoi
WS06-09-P
Ouchi, Ryo
WS27-22-P
Ouda, Ryota
WS02-14-P○WS02-15-P
WS04-02-P
Ouji Sageshima, Noriko
WS28-14-P
Ouji-Sageshima, Noriko○WS02-06-O/P
WS10-06-O/P
WS11-19-P
WS23-06-P
WS23-12-P
Owada, Takayoshi WS09-19-P
Owada, Yuji
WS04-11-O/P
WS20-07-P
Owaki, Atsuko
WS19-07-P○WS04-05-P
Oya, Yoshihiro○WS09-12-P
Oyamada, Yuki

Ozaka, Sotaro

Ozawa, Madoka
Ozawa, Tatsuhiko○WS07-09-P
WS17-16-P
WS25-02-P
WS03-13-P
WS12-25-P
WS11-22-P
WS22-19-P
WS26-09-O/P
WS26-21-P

P
Palaga, Tanapat

WS04-17-P
WS06-08-O/P
WS06-11-P○WS29-05-O/P
WS06-10-P
Pangarso, Alexandra Widita Swipratami
WS11-25-P
Park, Ah-Mee
WS06-03-O/P
Park, Eun Jeong
WS19-09-P
Park, Su Min
WS02-25-P
Park, Young-Soo
WS05-22-P
Parrish, Heather L. WS26-18-P
Pattarakankul, Thitiporn
WS04-17-P
WS29-05-O/P
Peining, Brian D
WS02-17-P
Phankeaw, Pimchanok
WS06-08-O/P
Piening, Brian
WS31-11-P
Pingen, Marieke
WS17-07-P
Potluri, Shobha
WS02-02-O/P
Priest, David
WS16-18-P○WS23-15-P○S08-04
Prinz, Marco
WS10-24-P
Pruksakorn, Vannakorn
WS06-08-O/P
WS06-11-P
WS06-10-P
Purwanto, Ignatius WS11-25-P

R
Rajamanickam, Venkatesh
WS27-16-O/P○WS10-03-O/P
Raveney, Ben
WS10-24-P
Reddy, Jayagopala WS16-08-O/P
Redmond, William WS27-16-O/P
WS31-11-P
Redmond, William L WS02-17-P
Restifo, Nicholas P. WS02-02-O/P
Ridgway, Rachel
WS02-07-O/P
Robinson, William H. S11-05
Rodewald, Hans-Reimer○S13-03
Ronchese, Franca ○S09-05
Rosales, Wesley
WS27-16-O/P○S10-02
Rothlin, CarlaS
S Cortez, Victor

WS05-06-O/P

Sabrina, Saima

WS14-08-P
WS22-11-P
Sachi, Nozomi
WS07-09-P○WS17-16-P
WS25-02-P
WS03-13-P
WS12-25-P
Saeki, Aiko
WS19-14-O/P
Saeki, Kazuko
WS29-15-O/P
WS29-24-P
Sagara, Hiroshi
WS04-06-O/P
Saijo, Shinobu
WS12-16-O/P○WS09-07-O/P
Saika, Azusa
WS13-13-O/P
WS30-03-O/P
Saito, Hiroaki
WS17-03-O/P○WS03-22-P
Saito, Masafumi
Saito, Mitsuru
WS11-16-P○WS12-11-P
Saito, Riho
○WS14-17-P
Saito, Riku
○WS17-08-O/P
Saito, Risa
Saito, Shinichi
WS14-08-P
Saito, Shuntaro
WS25-10-P
Saito, Suguru
WS07-01-O/P
WS25-03-O/P
Saito, Takashi
WS18-01-O/P○WS26-13-P
WS28-09-P
Saito, Takumi
WS29-22-P○WS04-01-O/P
Saito, Yasuyuki
WS20-13-P
Saito, Yoriko
WS11-08-P
WS22-04-O/P○WS08-18-P
Saito, Yuichi○WS22-11-P
Saitoh, Shinichi
Saitoh, Shin-Ichiroh ○WS04-06-O/P
WS30-20-P
Saitoh, Tatsuya
WS30-14-P
Sakabe, Takehiro
WS11-19-P
Sakagami, Mei
WS01-21-P
Sakagami, Takuro
WS11-14-O/P
Sakaguchi, Shimon WS01-05-O/P
WS16-02-O/P
WS16-04-O/P
WS16-13-P
WS16-18-P
C08-01
Sakaguchi, Taiki
WS07-11-P○WS16-14-P
Sakai, Ryota
Sakai, Seiichiro
WS14-14-O/P○WS26-22-P
Sakai, Yuki
Sakai, Yoshio
WS11-15-P
Sakai-Tagawa, Yuko WS28-01-O/P
Sakamori, Ryotaro WS23-13-O/P
Sakamoto, Akihiko WS08-17-P○WS28-16-P○WS17-13-O/P
Sakamoto, Eri
Sakamoto, Hiroshi WS18-11-P○WS12-24-P
Sakamoto, Kei
Sakamoto, Nao
WS27-07-P○WS25-06-O/P
Sakata, Daiji
Sakata, Daiji
WS09-12-P
Sakata-Yanagimoto, Mamiko
WS02-21-P
Sakatoku, Kazuki
WS27-06-P
Sakoguchi, Akihito ○WS03-08-O/P
Sakuishi, Kaori
WS06-21-P
Sakuraba, Shun
WS16-08-O/P

Sakurai, Keiichi
WS15-03-O/P
Salfeld, Jocheng
C11-01
Sanjo, Hideki
WS17-04-P○WS06-02-O/P
Sano, Shuhei
Sansom, Owen
WS02-07-O/P
Saonanon, Preamjit WS06-11-P
WS06-08-O/P
WS06-10-P
Sasada, Tetsuro
WS27-24-O/P
Sasaki, Atsuhi
WS12-07-O/P
Sasaki, Daisuke
WS12-24-P
Sasaki, Fumiyuki ○WS29-07-P
WS29-08-P
WS29-24-P
Sasaki, Harumi
WS08-21-O/P
Sasaki, Hirokazu
WS30-13-O/P
Sasaki, Izumi
WS29-10-O/P
Sasaki, Makoto
WS11-15-P
Sasaki, Soichiro
WS27-13-O/P
Sasaki, So-Ichiro
WS05-04-P
Sato, Ayaka
WS26-02-O/P○WS26-11-P
WS26-12-P○WS06-03-O/P
Sato, Fumitaka
WS31-14-P
Sato, Hayato
WS03-07-O/P
Sato, Katsuaki
WS27-08-P○WS08-04-P
Sato, Katsuya
Sato, Kayoko
WS13-17-O/P
Sato, Ko
WS03-07-O/P
Sato, Kosuke
WS01-06-O/P
WS01-15-P
WS07-05-O/P
WS10-21-P○WS18-14-P
WS18-20-P
Sato, Mami
WS04-08-O/P
WS15-06-O/P
WS15-07-O/P
WS15-18-P○WS31-10-P
Sato, Masashi
WS04-18-P
Sato, Ryo
WS22-03-O/P
Sato, Ryota
WS14-09-O/P
WS15-11-P○WS29-11-O/P
WS30-20-P
Sato, Taiki
WS18-11-P○WS25-08-P○WS04-03-O/P
Sato, Taku
Sato, Takumi
WS03-09-O/P
Sato, Tomohito
WS06-19-P
Sato, Tomoo
WS28-07-O/P
Sato, Wakiro
WS06-04-O/P
WS06-06-O/P
WS10-03-O/P
Sato, Katsuaki
WS07-02-P
WS20-17-P○WS05-02-P
Satoh, Masashi
WS05-12-P
Satoh, Minoru
WS31-06-O/P○T06-01
Satoh, Takashi
Satoh-Takayama, Naoko○WS05-18-O/P
WS05-20-P
Satooka, Hiroki
WS31-01-O/P○WS31-18-P
Satoshi, Yamaguchi WS26-09-O/P

206

Satou, Yorifumi

WS28-07-O/P
WS28-08-O/P
Satou, Yutaka
WS22-02-O/P
Satoyama, Toshiya WS14-12-P
Saukurai, Kohta
WS19-20-O/P○C05-02
Sawa, Naoki
Sawa, Shinichiro
WS05-16-O/P
WS07-13-P
WS07-14-P
WS20-09-O/P
WS22-22-P
WS28-06-O/P
Sawada, Anri
WS29-14-O/P
Sawada, Norie
WS06-09-P
Sawanobori, Yasushi○WS20-18-P
Sawasaki, Tatsuya WS11-12-P
Schutt, Charles
WS14-13-O/P
Seestaller Wehr, Laura
WS27-16-O/P
Seimiya, Hiroyuki
WS27-03-P
Seino, Ken-Ichiro
WS27-25-P○WS02-23-P
Sekai, Miho
Seki, Akihiro
WS11-15-P
Seki, Noriyasu
WS25-10-P○WS24-13-P
Seki, Takao
Seki, Toshiro
WS26-15-P○WS17-01-O/P
Sekine, Yuichi○WS16-05-O/P
Sekiya, Takashi
Sekul, Renate
WS12-03-P
Seo, Eun-Bi
WS02-25-P
Seo, Goo-Young
WS19-13-O/P
Serizawa, Kenichi
WS06-14-P
Serwold, Thomas
WS26-18-P
Seta, Yoshika
WS30-09-P
Sette, Alessandro ○S01-01
Seya, Tsukasa
WS02-27-O/P
Sezaki, Maiko
WS22-03-O/P○WS15-02-O/P
Shan, Yu
Shaw, Albert
WS18-25-P
Sher, Alan
WS18-04-O/P
Shevach, Ethan
WS04-05-P
Shi, Zhengzheng
WS05-18-O/P
Shibata, Kensuke ○WS03-06-O/P
WS05-01-O/P
Shibata, Takuma
WS29-11-O/P○WS30-20-P
Shibui, Nagito
WS26-02-O/P
WS26-12-P
Shibuya, Akira
S09-03WS05-05-O/P
WS05-14-O/P
WS10-02-O/P
WS21-01-O/P
WS25-15-O/P
WS05-03-O/P
Shibuya, Kazuko
S09-03WS05-14-O/P
WS10-02-O/P
WS16-10-P
WS21-01-O/P
Shichino, Shigeyuki WS02-01-P
WS07-17-O/P
WS10-06-O/P
WS14-15-O/P
WS20-02-O/P
Shichita, Takashi ○OT08○S08-01

WS14-14-O/P
WS17-12-O/P
WS20-06-P
WS24-16-P
Shida, Hisatoshi
WS28-16-P
Shigehiro, Tsukasa ○WS11-10-O/P
Shigenaga, Ayako WS04-15-P
Shiina, Takashi
WS31-08-O/P
Shiku, Hiroshi
WS11-26-P
Shima, Yoshio
WS04-13-O/P
Shimada, Takashi
WS02-17-P○WS31-11-P
Shimamura, Hinano WS21-08-O/P
Shimaoka, Motomu WS05-20-P
WS19-09-P
Shimasaki, Nodoka WS09-10-P
WS09-15-P
WS24-14-P
WS29-03-P
WS29-04-P
Shimba, Akihiro
WS21-02-O/P
Shime, Hiroaki
WS16-13-P
Shimizu, Akira
WS29-14-O/P
Shimizu, Atsushi
WS06-09-P
Shimizu, Haruka
WS02-01-P○WS18-24-P
Shimizu, Kanako
WS02-08-O/P
WS03-11-P
WS11-18-P○WS25-17-O/P
Shimizu, Kenji
WS24-01-O/P
WS24-06-P
WS24-07-P
Shimizu, Kikiko
WS28-10-P
Shimizu, Masahito WS28-22-P
Shimizu, Masaru
WS15-11-P
Shimizu, Masumi
WS29-07-P○WS29-08-P
WS29-06-O/P
Shimizu, Miho
WS04-10-P
WS04-18-P
Shimizu, Takashi
WS03-06-O/P○WS14-13-O/P
Shimizu, Takeyuki
WS02-19-P
WS31-08-O/P
Shimizu, Tomoka
WS26-15-P
Shimizu, Tomoko ○WS19-22-P
Shimizu, Yu
WS19-11-P
Shimizu, Yuta
WS31-05-O/P
Shimoda, Mayuko ○WS08-09-O/P
Shimokawa, Chikako○WS12-19-P
WS18-13-P
Shimonishi, Shohei T07-01
Shimotada, Ryusei WS12-14-P
Shimoyama, Atsushi WS13-13-O/P
WS30-03-O/P
Shimoyama, Shuhei WS17-06-O/P○WS04-15-P
Shimura, Eri
Shin, Jay
WS22-04-O/P
Shinkura, Reiko
WS08-13-O/P
Shinnakasu, Ryo
WS12-05-P
Shinomiya, Takeshi WS03-07-O/P
Shinozaki, Seiji
WS21-12-P○WS29-16-P
Shinya, Yari
Shioda, Ryotaro
WS29-15-O/P
Shiota, Ayaka
WS21-12-P
Shiozawa, Kazuko WS15-03-O/P

Shiozawa, Shunichi ○WS15-03-O/P○WS28-25-P
Shirai, Akihiro
Shirai, Kunihiro
WS28-12-P○WS13-04-O/P
Shirai, Taiichiro
Shirai, Takanobu
WS02-23-P○WS15-19-P
Shirakawa, Yuki
Shirasaki, Yoshitaka WS05-19-P
WS25-12-O/P
WS30-15-P
Shirouzu, Mikako
WS28-09-P
Shitaoka, Kiyomi
WS26-09-O/P
Shivdasani, Ramesh○S04-01
Shizu, Manami
WS04-10-P
WS04-18-P
Shoda, Hirofumi
WS15-08-O/P
Shultz, Leonard
WS22-04-O/P
Shunyi, Li
WS16-07-O/P
Simons, Noah
WS27-16-O/P○S11-01
Slavov, Nikolai
Smothers, James
WS27-16-O/P
So, Takanori
WS17-03-O/P
WS18-17-P○WS26-02-O/P
WS26-11-P
WS26-12-P○WS11-16-P
Sobu, Ryuta
Soh, Hinata
WS29-21-P
Sondergaard, Jonas WS23-15-P
Søndergaard, Jonas○WS16-18-P
Sonomoto, Koshiro WS15-14-P
Sonomura, Kazuhiko WS27-14-O/P
Sonomura, Kazuhiro S12-01
Sprent, Jonathan
WS18-04-O/P○WS18-22-P
Srirat, Tanakorn
WS11-03-P
Stadinski, Brian
S05-03
Stadler, Volker
WS12-03-P
Su, Helen
S06-03Suda, Wataru
WS06-04-O/P
Sudo, Koichi
WS19-17-P
Suehara, Yasuhito WS02-21-P
Suematsu, Makoto WS27-10-O/P○WS12-01-P
Sugahara, Ko
Sugahara, Kunio
WS25-10-P
Suganami, Takayoshi S04-04
Sugata, Kenji
WS28-07-O/P
Sugihara, Risa
WS04-01-O/P
WS20-13-P
Sugimoto, Naoshi
WS23-04-O/P
Sugimoto, Yukihiko WS29-24-P
Sugita, Masahiko
WS26-05-O/P
WS26-17-P
Sugiura, Daisuke ○WS24-01-O/P
WS24-06-P
WS24-07-P
Sugiura, Yuki
WS27-14-O/P
Sugiyama, Hiromu WS12-19-P
Sugiyama, Ko
WS27-20-O/P
Sugiyama, Yuma ○WS08-17-P
Sujino, Tomohisa
WS18-15-P
WS19-12-O/P
Sultana, Farzana
WS10-19-P
Suma, Sakurako ○WS02-21-P
Sumida, Takayuki
WS15-11-P
WS15-17-P
Sumida, Tomokazu WS18-25-P

Sumimoto, Hidetoshi WS02-20-O/P
Sumiya, Eriko
WS05-16-O/P
WS20-09-O/P○WS22-22-P
WS07-14-P
Sumiyoshi, Mami ○WS18-13-P
Sun, Xiao
WS13-13-O/P○WS30-03-O/P○WS02-13-P
Sun, Xin
WS02-15-P
Sung, Yi-Jung
WS27-02-P
Sun-Wada, Ge-Hong WS04-06-O/P
Supriyadi, Eddy
WS11-25-P
Sutaryo, Sutaryo
WS11-25-P
Suto, Akira
WS05-15-P
WS18-12-P
WS21-17-P
Suto, Hajime
WS09-06-O/P○WS06-09-P
Sutoh, Yoichi
Suyama, Mikita
WS13-06-O/P
Suzuki, Akari
WS23-01-O/P
WS23-03-O/P○WS20-20-O/P
Suzuki, Akio
Suzuki, Ayano
WS26-12-P
Suzuki, Haruka
WS11-23-O/P
Suzuki, Harukazu
WS22-13-P
Suzuki, Harumi
WS10-17-P
Suzuki, Hibiki
WS10-21-P
Suzuki, Katsuya
WS10-15-P
WS15-12-P
WS25-10-P○C01-02○C05-01
Suzuki, Kazuhiro
WS13-04-O/P
WS17-10-O/P
Suzuki, Kazuo
WS31-09-P
Suzuki, Keita
WS03-25-P
Suzuki, Kensuke
WS18-18-P
WS31-16-P
Suzuki, Koichiro
WS10-05-O/P
Suzuki, Kotaro
WS18-12-P
WS21-17-P
WS05-15-P
Suzuki, Makiko
WS29-23-P
Suzuki, Saori
WS12-09-P○WS27-15-P
Suzuki, Sayaka○OT11
Suzuki, Shinobu
Suzuki, Shunji
WS04-13-O/P
WS24-15-O/P
Suzuki, Tadaki
WS12-06-O/P
Suzuki, ToshihikoWS03-01-O/P
WS14-02-P
Suzuki, Toshiyasu ○WS02-07-O/P
Suzuki, Tsuyoshi
WS14-07-P
Suzuki, Yusuke
WS08-14-O/P
WS29-15-O/P
Suzuki, Yutaka
WS27-23-O/P

T
Tachikawa, Daisuke WS14-12-P
Tada, Yuki
WS14-11-O/P○WS29-13-P
Taguchi, Tomohiko ○S15-05
Tahara, Hideaki
WS05-04-P
Tahara-Hanaoka, Satoko
S09-03207○OT09○WS09-02-O/P
WS09-10-P
WS09-15-P
WS24-14-P
WS29-03-P
WS29-04-P
Tajima, Masaki
WS18-18-P
WS24-03-P
WS31-16-P
Tajiri, Kazuto
WS26-21-P
Takaba, Hiroyuki
WS11-20-O/P
Takada, Kensuke ○WS18-05-O/P
Takada, Minoru
WS10-05-O/P
Takada, Yoshiaki
WS05-09-P
WS22-24-P○WS03-05-O/P
Takaesu, Giichi
WS12-14-P
Takagi, Koichi
WS21-14-P
Takagi, Rie
WS25-05-O/P
Takagi, Sayaka
WS09-10-P
WS09-15-P
WS24-14-P
WS29-03-P
WS29-04-P
Takagi, Shinsuke
WS11-08-P
Takahama, Shokichi WS10-05-O/P
WS12-08-P○WS23-13-O/P
WS28-08-O/P
Takahara, Kazuhiko WS19-17-P
WS30-08-O/P
Takahashi, Daisuke WS06-05-O/P
WS16-07-O/P○WS19-13-O/P
WS19-18-O/P
WS19-14-O/P
Takahashi, Fumio
WS10-24-P
Takahashi, Haruka WS15-08-O/P○WS25-12-O/P
Takahashi, Hayato WS06-01-O/P
Takahashi, Hidenori WS10-09-P
Takahashi, Kazufusa WS07-17-O/P
WS20-02-O/P○WS21-08-O/P
Takahashi, Kazuhisa WS21-11-P
Takahashi, Kyoko
WS19-23-P
Takahashi, Munetomo
WS02-01-P
Takahashi, Reiko ○WS18-16-P
Takahashi, Satoru WS15-17-P
WS29-18-P
Takahashi, Sonoko S14-02○WS07-19-P
WS09-05-O/P
Takahashi, Takeshi WS23-05-P
Takahashi, Toshikazu WS23-06-P
Takahashi, Yoshimasa
WS05-11-O/P
WS12-02-P
WS12-08-P
WS19-23-P
WS12-05-P
Takai, Tomoko
WS04-01-O/P
WS20-13-P
Takai, Toshiro
WS09-06-O/P
Takaki, Satoshi
WS12-13-P
Takakura, Masahito WS29-20-P
Tai, Yuki
Tajima, Ayumi

Takamatsu, Hyota

WS15-01-O/P
WS15-04-O/P
WS24-18-P
WS30-19-O/P○WS21-02-O/P
Takami, Daichi○WS02-09-P
Takami, Mariko
WS02-10-P
Takamori, Kenji
WS09-06-O/P○S07-03
Takamura, Shiki
WS04-09-P
WS27-05-P
Takano, Junichiro
WS04-17-P○WS30-05-O/P
Takano, Shun
WS30-17-P
Takano, Tomohiro ○WS12-02-P
Takano, Tomomi
WS03-10-P
Takao, Kenjiro
WS29-23-P○S10-03
Takaoka, Akinori
Takaori-Kondo, Akifumi
WS22-04-O/P
Takashi, Kyoko
WS19-06-P
Takashima, Ken
WS08-11-O/P
WS21-09-O/P○WS30-07-O/P
Takasuga, Shunsuke WS05-05-O/P
WS21-01-O/P
Takata, Sadaaki
WS11-08-P
Takata, Toshitaro
WS13-10-O/P
Takaya, Akiko
WS03-19-P
Takayama, Kazuo
WS08-01-O/P
Takayanagi, Hiroshi S02-04
WS01-04-O/P
WS11-20-O/P
WS29-17-P○C07-01
Takebe, Takanori ○E06
○WS28-23-P
Takeda, Kazuya
Takeda, Kazuyoshi WS24-05-O/P
WS27-13-O/P
Takeda, Kiyoshi
WS07-03-O/P
WS07-06-O/P
WS07-11-P
WS17-14-P
WS19-01-O/P
WS20-04-O/P○S16-03
WS12-25-P
Takeda, Yuji
WS14-08-P
WS22-11-P
Takeda, Yuri
WS04-04-O/P
Takedomi, Hironobu WS09-20-P
Takehara, Tetsuo
WS23-13-O/P
Takemasa, Daichi
WS29-22-P
Takemura, Naoki ○WS30-14-P
Takeshima, Yuki
WS08-09-O/P
Takeshita, Atsuro
WS06-18-P○WS25-14-P
WS25-13-O/P
Taketomi, Akinobu WS27-20-O/P
Takeuchi, Arata
WS11-21-P
WS26-06-O/P
WS26-10-P
Takeuchi, Hideaki
WS14-12-P
Takeuchi, Kazuhiro WS29-14-O/P
Takeuchi, Masaru
WS06-19-P
Takeuchi, Osamu
WS04-14-P
WS14-18-P
WS18-08-O/P

WS22-01-O/P
WS22-16-P
Takeuchi, Shugo
WS14-12-P
Takeuchi, Tadashi
WS05-18-O/P
WS12-19-P
Takeuchi, Tsutomu WS15-12-P
WS25-10-P
Takeuchi, Yasuhide WS11-23-O/P
Takeuchi, Yusuke
WS07-08-P○WS15-09-O/P
WS25-09-O/P○WS06-04-O/P
Takewaki, Daiki
Takeyama, Ami
WS05-01-O/P
Taki, Shinsuke
WS17-04-P
Takiguchi, Mitsuyoshi WS19-10-P
Takizawa, Hitoshi
WS22-03-O/P
WS23-04-O/P
Takubo, Tomoki
WS27-15-P
Tamai, Hiroya
CE01-1○T01-01
Tamada, Koji
○T05-01
Tamamura, Hiroyasu WS11-15-P
Tamaoki, Naritaka WS02-02-O/P
Tamechika, Shin-Ya WS15-16-P○WS23-07-P
Tamura, Kai
WS15-07-O/P
Tamura, Naoto
WS08-03-P
WS22-12-P
WS29-22-P
Tamura, Tomohiko WS22-15-P
WS27-17-P○WS28-18-P
Tamura, Yumi
Tan, Benjy Jek Yang ○WS28-07-O/P○WS08-12-P
Tanabe, Kano
Tanabe, Ryuto
WS27-07-P○WS22-07-O/P
Tanabe, Yamato○WS21-11-P
Tanabe, Yuki
○WS09-19-P
Tanaka, Ayae
Tanaka, Masato
WS20-05-O/P○S04-04
Tanaka, Miyako
Tanaka, Nobuyuki
WS12-21-P○WS15-15-P
Tanaka, Reika○WS01-07-O/P
Tanaka, Sachi
WS01-19-P
Tanaka, Sakae
WS15-08-O/P
WS25-12-O/P
Tanaka, Shigeru
WS05-15-P
WS18-12-P
WS21-17-P
Tanaka, Shin
WS31-06-O/P
Tanaka, Shinya
WS24-12-P○WS30-08-O/P
Tanaka, Shuto○WS10-16-P
Tanaka, Takashi
Tanaka, Toshio
WS25-11-P
Tanaka, YoshihikoWS03-14-P
WS03-23-P
WS12-15-P
Tanaka, Yoshimasa WS16-08-O/P
Tanaka, Yoshiya
WS15-14-P
WS31-06-O/P○C09-01
Tanaka, YosihikoWS03-16-P○WS15-05-O/P
Tanaka, Yuki
WS15-12-P○WS15-13-P
WS17-06-O/P
WS19-10-P
WS31-08-O/P

Tanaka, Yuriko

WS10-18-P
WS26-14-P○WS31-15-P
Tanegashima, Kosuke
WS17-08-O/P
Tanegashima, Tokiyoshi
WS27-26-P
Taneno, Akira
WS03-09-O/P
Tanese, Keiji
WS09-04-O/P
Tang, Ce
WS06-12-P
Tang, Miao
WS13-10-O/P
Tani, Haruka
WS07-11-P
Taniguchi, Hinata
WS09-10-P
WS09-15-P
WS24-14-P○WS29-03-P
WS29-04-P
Taniguchi, Mayumi WS12-10-P
Taniguchi, Mugen ○WS19-01-O/P
Taniguchi, Shuichi WS11-08-P
Taniguchi, Toshibumi WS09-19-P
Tanimura, Reona ○WS15-11-P
Tanino, Mishie
WS27-20-O/P
Tanishita, Yuko
WS12-24-P
Taniuchi, Ichiro
S06-05
WS01-02-O/P
WS01-09-P
WS01-14-P
WS16-06-O/P
WS23-02-O/P○WS26-24-P
Tanno, Hidetaka
Tanno, Hiromasa
WS03-07-O/P○WS04-19-P
Tanoue, Keiko
WS14-04-P
WS29-19-P
Tartey, Sarang
WS04-14-P
Tarumi, Masato
WS15-05-O/P
Tasaki, Sonoko
WS03-14-P
WS03-16-P
WS03-23-P
WS12-15-P
Tatematsu, Megumi ○WS05-05-O/P
WS21-01-O/P
Tateno, Hiroaki
S09-03
Tatsuhiko, Ozawa
WS26-16-P○WS20-15-O/P
Tatsumi, Naoya
Tayama, Shunichi
WS01-06-O/P
WS01-15-P○WS07-05-O/P
WS10-21-P
WS18-04-O/P
WS18-14-P
WS18-20-P
Taylor, Naomi
WS11-11-O/P○WS27-18-P
Temizoz, Burcu○WS13-11-O/P
Tenno, Mari
Teoh, Yong Bin
WS19-10-P○WS02-11-P
Terabe, Masaki
Terada, Koji
WS10-11-P
WS26-08-O/P
Terahara, Kazutaka WS12-02-P
Terao, Chikashi
WS23-01-O/P
WS23-03-O/P
Terasaki, Mika
WS29-14-O/P
Terasaki, Yasuhiro WS29-14-O/P
Terashima, Asuka ○WS29-17-P
Terashima, Yuya
WS29-14-O/P
Terooatea, Tommy WS05-20-P

208

Terooatea, Tommy Walter
WS05-17-O/P
Tetteh, Doris Narki ○WS22-23-P
WS22-10-O/P○WS21-03-O/P
Tezuka, Saya
Thelin, Martin A.
WS26-18-P
Thi Viet My, Ha
WS26-09-O/P
Thinyakul, Chanida WS08-09-O/P
Tiwari, Prabha
WS09-07-O/P○WS29-14-O/P
Toda, Etsuko
Toda, Masaaki
WS06-18-P
WS25-13-O/P
WS25-14-P
WS27-01-P
Todo, Kagefumi
WS13-02-P○WS28-21-P
Toda, Tatsushi
WS06-21-P
Todo, Tomoki
WS02-27-O/P
Todoroki, Yasuyuki ○WS31-06-O/P
WS15-14-P
Togami, Yuki
WS23-15-P○C10-01
Togashi, Yosuke○A02-03
Toguchi, Julia
WS12-14-P
Toguchi, Mariko
WS16-14-P○WS02-16-P
Tokita, Serina
WS02-18-P
WS11-13-P
Tokoyoda, Koji
WS01-20-P
WS01-21-P
WS03-19-P
WS06-15-P
WS08-21-O/P
WS10-01-O/P
WS27-15-P
Tokuda, Nobuko
WS20-18-P
Tokumaru, Yosuke WS18-18-P○WS31-16-P
Tokumasu, Miho
WS18-23-P
Tokushige, Koji
WS04-16-O/P
WS21-06-O/P
WS23-09-O/P
Tomimaru, Yoshito WS10-09-P
Tominaga, Mitsutoshi WS09-06-O/P
Tominaga, Moe
WS07-02-P○WS20-17-P
WS27-08-P
Tomita, Yusuke
WS11-14-O/P
Tomiyasu, Noriyuki WS18-06-O/P
Tomizawa, Yuji
WS06-02-O/P
Tomizawa-Shinohara, Haruna
WS06-14-P
Tomono, Susumu
WS08-22-O/P
WS13-14-O/P
WS30-18-P
Tomura, Michio
WS21-18-P
Torigoe, ToshihikoWS02-16-P
WS02-18-P
WS08-02-P
WS11-13-P○WS16-07-O/P
Toriumi, Hiroki
Toujou, Takehiko
WS14-05-P○WS10-08-P
Toyoda, Mako
WS28-03-O/P○WS03-14-P
Toyonaga, Kenji
WS03-16-P
WS03-23-P
WS12-15-P

Toyoshima, Haruka WS27-15-P
Toyoshima, Yujiro
WS27-20-O/P
Toyota, Hiroko
WS11-21-P
WS26-06-O/P
WS26-10-P
Tran, Eric
WS02-17-P
WS31-11-P
Triasih, Rina
WS11-25-P
Tsubata, Takeshi
WS13-10-O/P
WS16-15-O/P
Tsuboi, Hiroto
WS15-10-P
WS15-11-P
WS15-20-P
Tsuchida, Marina
WS30-13-O/P
Tsuchida, Yumi
WS25-12-O/P
Tsuchiya, Haruka ○S02-01
WS15-08-O/P
WS25-12-O/P
Tsuchiya, Soken
WS29-24-P
Tsuda, Masato
WS19-23-P
Tsuda, Masayuki
WS13-09-P○WS08-21-O/P
Tsuda, Shogo
WS27-15-P
Tsuiji, Makoto
WS13-17-O/P
Tsuji, Kaori
WS12-07-O/P○WS07-01-O/P
Tsuji, Noriko
WS25-03-O/P
Tsuji-Kawahara, Sachiyo
WS08-05-P
Tsujimoto, Kohei
WS15-01-O/P○WS30-19-O/P
Tsujimura, Takahiro WS05-22-P
Tsukahara, Narutoshi○WS13-18-P
Tsukahara, Tomohide WS08-02-P
Tsukamoto, Hirotake○WS11-14-O/P
Tsukamoto, Tetsuo WS08-05-P
Tsukimoto, Shota ○WS08-05-P
Tsukinoki, Keiichi
WS19-22-P
Tsukui, Daisuke
WS30-12-P
Tsukumo, Shin-Ichi WS15-06-O/P
Tsumiyama, Ken
WS15-03-O/P○S03-01
Tsumoto, Kohei
Tsumoto, Kouhei
WS28-15-P
Tsunematsu, Takaaki○WS04-08-O/P
WS15-07-O/P
WS15-18-P
WS31-10-P
Tsuneoka, Yousuke WS19-04-P
Tsuneto, Motokazu ○WS14-16-P
Tsunetsugu-Yokota, Yasuko
WS28-19-P
Tsuneyama, Koichi WS14-11-O/P
WS29-13-P
Tsunoda, Ikuo
WS06-03-O/P
WS31-14-P
Tsunoda, Junya
WS05-09-P○WS02-01-P
Tsunoda, Mikiya
WS18-24-P
Tsunoda, Tatsuhiko WS20-05-O/P○WS13-09-P
Tsuru, Emi
Tsurumaki, Nobuhide T09-01
Tsuruoka, Nobuhide WS09-19-P
Tsutsui, Yuta
WS26-12-P○WS20-06-P
Tsuyama, Jun
WS24-16-P○WS09-10-P
WS09-15-P
WS24-14-P
WS29-03-P
WS29-04-P
Tulyeu, Janyerkye
WS16-18-P
WS23-15-P
Tsuzuki, Hikaru

U○WS27-13-O/P
WS16-10-P
WS24-05-O/P
Uchida, Naoyuki
WS11-08-P
Uchida, Shumpei ○WS02-27-O/P
Uchio, Akihiro
WS15-08-O/P
Udaka, Keiko
WS02-19-P
WS28-03-O/P○WS31-08-O/P
Udono, Heiichiro
WS18-23-P
Ueda, Mitsuharu
WS28-07-O/P○WS03-11-P
Ueda, Shogo
Ueda, Yoshihiro
WS01-18-P○WS17-09-O/P
WS22-09-O/P
WS22-17-P
Ueda, Yusuke
WS29-20-P
Ueha, Satoshi
WS02-01-P
WS10-06-O/P
WS14-15-O/P
WS18-24-P○WS22-16-P
Uehata, Takuya
Uematsu, Takayuki ○WS03-10-P
Uemura, Sotaro
WS05-19-P
WS25-12-O/P
Ueno, Hideki
WS11-23-O/P
WS18-03-O/P
WS20-08-P
WS23-16-P○WS15-14-P
Ueno, Masanobu
Ueno, Shiori
WS28-15-P
Ueno, Takamasa
WS28-03-O/P
WS10-08-P
Ueno, Tastuya
WS01-13-P
Ueno, Tatsuya
WS02-04-O/P
Ueta, Hisashi
WS20-18-P
Ujie, Michiko
WS28-01-O/P
Ukita, Masayo
WS11-23-O/P
Umekage, So
WS06-09-P
Umemoto, Eiji
WS07-03-O/P
WS20-04-O/P
Umemura, Masayuki WS03-05-O/P○WS12-14-P
Umezawa, Natsuka WS30-13-O/P
Umezu, Takumi
WS13-11-O/P
Uno, Kazuko
WS23-08-O/P○WS25-11-P
Urakami, Hitoshi ○WS09-11-P
WS17-11-O/P
WS21-20-P
Uraki, Ryuta
WS16-13-P○WS28-01-O/P○WS28-04-O/P
Urano, Emiko
Uryu, Mizuki
WS13-17-O/P
Ushio, Aya
WS31-10-P
Usui, Toshiaki
WS29-18-P
Uta, Daisuke
WS09-20-P
Ucche, Sisca
Uchida, KoichiroUto, Kenichi
Uto, Tomofumi

WS15-03-O/P
WS07-02-P
WS20-17-P○WS27-08-P

V
Van Hagen, P. Martin WS06-08-O/P
WS06-10-P
Verzi, Michael
WS02-07-O/P
Virakul, Sita
WS06-08-O/P○WS06-10-P
WS06-11-P
Visamol, Sopita
WS06-10-P○WS02-02-O/P
Vizcardo, Raul

WS11-25-P
Widyagarini, Amrita ○WS24-08-P
Wilson, Gillian
WS17-07-P
Wing, James
WS16-18-P
WS23-15-P
Wong, Patrick
WS18-25-P
Wongphoom, Jutamas
WS06-11-P
Wongprom, Benjawan
WS29-05-O/P
WS04-17-P○WS14-15-O/P
Wu, Bin
Wu, Jing
WS27-01-P
Wu, Zhiliang
WS12-17-P

X
W
Wada, Motoshi
WS18-14-P
Wada, Yoh
WS04-06-O/P
Wada, Yusuke
WS30-15-P
Wakabayashi, Ayako○WS19-07-P
Wakamatsu, Ei
WS11-21-P
WS26-06-O/P○WS26-10-P
Wakazuki, Momoka WS10-01-O/P○S08-05
Wake, Hiroaki
Wang, Bo
WS23-04-O/P○WS04-12-P
Wang, Duo
Wang, Hexing
WS04-16-O/P
WS21-06-O/P○WS23-09-O/P○WS30-04-P
Wang, Jiaqi
Wang, Qingyang
WS19-13-O/P
Wang, Shangyi
WS18-05-O/P
Wang, Tianyi
WS02-22-P
Wang, Wei-Le
WS20-19-O/P
Wang, Yangsong
WS01-13-P○WS01-16-P
WS02-04-O/P○WS22-03-O/P
Wang, Yuxin
Washizaki, Ayaka
WS10-05-O/P○WS28-08-O/P
WS28-19-P
Watanabe, Aruma WS17-13-O/P
Watanabe, Atsushi WS25-08-P
Watanabe, Hideaki WS18-20-P
Watanabe, Hiroshi ○WS24-09-O/P
Watanabe, Hitomi
WS07-08-P
WS25-09-O/P○WS28-13-P
WS15-09-O/P
Watanabe, Keisuke ○WS11-05-O/P
Watanabe, Masashi WS02-15-P
WS04-02-P
Watanabe, Miyuki ○WS30-16-O/P
Watanabe, Sho
WS27-26-P
Watanabe, Takashi WS06-01-O/P
Watanabe, Takeshi WS22-18-P
Watanabe, Toshiyuki WS02-13-P
Watanabe, Yuji
WS04-06-O/P
Watarai, Masahisa WS03-06-O/P
Watnabe, Mahiro ○WS31-20-P○WS16-03-P
Wei, Yuxi
Widjajanto, Pudjo Hagung

209

Xavier, Ramnik
Xiang, Huihui
Xiao, Zhengtao
Xu, Huaigeng
Xuyang, Tang

WS07-04-O/P
WS27-20-O/P○WS27-24-O/P
WS27-27-P
WS23-04-O/P
WS13-11-O/PY
Y. Kimura, Motoko WS02-04-O/P○E05
Yachie, Nozomu○WS08-07-O/P
Yada, Yutaro
Yafei, Liu
WS03-12-P
Yagita, Hideo
WS02-13-P
WS11-24-P
WS15-06-O/P
WS19-04-P
WS31-09-P○WS17-14-P
Yagita, Mayu
Yaguchi, Tomonori WS27-10-O/P
Yahagi, Ayano
WS13-16-P
Yahagi, Yoshiyuki
WS08-03-P
Yakabe, Kyosuke ○WS09-18-P
Yamada, Daiki
WS19-19-O/P
Yamada, Daisaku
WS10-09-P
Yamada, Naruomi
WS14-16-P
Yamada, Satoshi ○WS31-12-P
Yamada, Shuichi
WS05-22-P
Yamada, Soga
WS26-15-P
Yamada, Takahiro
WS19-14-O/P
WS28-06-O/P○WS21-01-O/P
Yamada, Toshiki
Yamada, Zento
WS07-22-P○WS06-01-O/P
Yamagami, Jun
Yamagata, Kaoru
WS15-14-P
Yamagata, Kyouhei WS28-16-P
Yamagishi, Mai
WS05-19-P
WS25-12-O/P
Yamaguchi, Masaya WS03-04-O/P
Yamaguchi, Munechik
WS02-08-O/P
Yamaguchi, Tomokazu
WS27-23-O/P
Yamaguchi, Tomoyuki○WS01-08-P
Yamaguchi, Yoko
WS03-15-P○WS14-06-O/P
Yamaguchi, Yuta
Yamaji, Ken
WS22-12-P
WS29-22-P

Yamaji, Taiki
WS06-09-P
Yamakawa, Natsuko○WS03-20-P
Yamakura, Fumiyuki WS04-15-P
Yamamae, Yui
WS05-04-P○WS05-21-P
Yamamoto, Kazuhiko WS23-01-O/P
WS23-03-O/P
WS24-12-P
Yamamoto, Kazutaka WS11-15-P
Yamamoto, Lisa
WS04-16-O/P
Yamamoto, Masahiro WS03-03-O/P
WS03-24-P
WS06-13-P
WS25-06-O/P
Yamamoto, Masayuki WS04-07-P
Yamamoto, Mizuki WS28-09-P
WS28-12-P
Yamamoto, Natsuo ○WS14-07-P
Yamamoto, Norio
WS21-12-P
Yamamoto, Raizo
WS11-01-P○WS21-06-O/P
Yamamoto, Risa
Yamamoto, Ryohei WS11-16-P
Yamamoto, Shinichi ○WS10-22-P
Yamamoto, Takuya WS10-05-O/P
WS10-09-P
WS12-08-P
WS23-13-O/P
WS28-08-O/P
WS28-19-P
Yamamoto, Yuichiro WS08-01-O/P
Yamamura, Takashi WS06-04-O/P
WS06-06-O/P
WS10-03-O/P
WS10-24-P
WS16-08-O/P
Yamanaka, Miyako WS30-12-P
Yamane, Keita
WS28-18-P
Yamane, Takashi
WS15-03-O/P
Yamane, Toshiyuki WS22-10-O/P
Yamano, Tomoyoshi WS02-26-P
WS31-04-O/P○WS10-07-O/P
Yamano, Yoshihisa WS28-07-O/P○S01-02
Yamasaki, Sho
S11-04WS03-06-O/P
WS05-01-O/P
WS10-10-P
WS14-13-O/P
WS18-06-O/P
WS26-22-P
WS28-12-P
WS30-16-O/P
Yamasaki, Takaya ○WS22-15-P
Yamasaki, Takeshi ○WS19-10-P
Yamashita, Erika ○WS11-01-P
Yamashita, Kimihiro WS03-22-P
Yamashita, Masakatsu○OT15
WS09-03-O/P
Yamashita, Motoi ○OT06
S06-05
Yamashita, Nahoko WS18-23-P
Yamashita, Naomi WS21-15-P
Yamauchi, Saya
WS28-16-P
Yamaue, Hiroki
WS08-02-P
Yamaura, Haruki
WS13-13-O/P

WS30-03-O/P
Yamayoshi, Seiya
WS28-01-O/P
Yamazaki, Hidetoshi WS22-10-O/P
WS22-23-P
Yamazaki, Rika
WS30-04-P
Yamazaki, Sayuri
WS14-01-P
WS16-13-P○WS19-04-P
Yamazaki, Soh
WS24-13-P
Yamazaki, Tatsuya WS08-22-O/P
WS30-18-P○WS13-14-O/P
Yamazaki, Yasuhiro WS02-02-O/P
Yanagi, Masahiro ○WS18-11-P
WS25-08-P
Yanagihara, Katsunori
WS12-24-P○WS14-03-O/P
Yanai, Hideyuki
Yanamandra, Niranjan
WS27-16-O/P○WS04-11-O/P
Yang, Shuhan
WS20-07-P
Yang, Zhuohao
WS25-12-O/P
Yang, Ziying
WS01-06-O/P
WS01-15-P
WS07-05-O/P
WS18-14-P○WS18-20-P
WS27-07-P
Yano, Hiromu
WS11-14-O/P
Yano, Yutaka
WS06-18-P
WS25-13-O/P
WS25-14-P
Yari, Shinya
WS08-20-O/P
Yashiro, Takuya
WS04-07-P○WS21-19-P
WS20-11-P
Yasuda, Atsushi
WS26-15-P○WS29-20-P
Yasuda, Eriko
Yasuda, Keiko
A01-02○WS03-17-P
Yasuda, Koubun
WS07-15-O/P
Yasuda, Shinsuke
WS17-05-O/P
WS30-13-O/P
WS12-06-O/P
Yasuda, Tomoharu WS20-03-P
WS28-18-P
WS05-13-P
Yasuhara, Atsuhiro WS28-01-O/P
Yasui, Teruhito
WS28-15-P
Yasukawa, Shinsuke WS09-12-P○WS14-18-P
Yasukura, Shota
Yasuma, Taro
WS06-18-P
WS25-13-O/P
WS25-14-P
WS27-01-P
Yasuno, Hideyuki
WS06-14-P
Yasutomi, Yasuhiro WS03-20-P
WS28-04-O/P
Yasutomo, Koji
WS15-06-O/P
WS19-16-P○WS02-25-P
Ye, Sang-Kyu○WS06-12-P
Ye, Xiao-Qi○WS10-24-P
Yeh, Tzu Wen
Yin, Wenqiang
WS29-17-P
Yiwei, Liu
WS16-07-O/P○WS07-06-O/P
Yokoi, Takehito
Yokoi, Yuki
WS19-11-P

Yokomizo, Takehiko WS29-15-O/P
WS29-24-P
Yokosuka, Tadashi WS11-21-P
WS26-06-O/P
WS26-10-P
Yokota, Masaya
WS21-17-P
Yokoyama, Kazumasa
WS06-02-O/P
Yokoyama, Kotoko WS31-11-P
Yokoyama, Shigeyuki WS26-21-P
Yoneyama, Mitsutoshi
WS30-11-P
Yonezawa, Atsushi WS31-11-P
Yonezawa, Fumiya WS21-10-P
Yorozu, Keigo
WS06-14-P
Yoshida, Haruka
WS27-17-P
Yoshida, Hideyuki ○OT05○S05-01
S06-05
WS21-01-O/P
Yoshida, Hiroki
WS03-24-P
WS04-01-O/P
WS20-13-P
WS25-06-O/P
WS12-20-O/P
Yoshida, Kazuyo
WS28-25-P○WS23-14-P
Yoshida, Kengo
Yoshida, Michiko ○WS03-07-O/P
Yoshida, Nanami
WS09-10-P
WS09-15-P
WS24-14-P
WS29-03-P○WS29-04-P
Yoshida, Shigeto
WS28-16-P
Yoshida, Takanobu ○WS21-09-O/P
Yoshida, Yasuhiro
WS04-12-P
Yoshida, Yutaka
WS12-21-P○WS21-21-P
Yoshido, Kana
Yoshie, Osamu
WS25-01-P
WS25-07-P
Yoshihara, Asumi
WS04-20-P○WS20-01-P○WS15-08-O/P
Yoshihara, Risa
WS25-12-O/P
Yoshii, Ken
WS13-13-O/P
WS30-03-O/P
Yoshikawa, Fabio ○WS12-16-O/P
Yoshikawa, Soichiro WS06-02-O/P
WS09-11-P
WS17-11-O/P
WS21-20-P
Yoshikawa, Toshiaki ○WS11-06-O/P
Yoshimatsu, Yusuke ○WS18-15-P
Yoshimoto, Keiko
WS10-15-P
WS15-12-P○WS25-10-P
Yoshimoto, Takayuki WS17-13-O/P
Yoshimura, Akihiko S10-01
WS02-03-O/P
WS10-22-P
WS10-23-P
WS11-04-O/P
WS11-17-P
WS14-17-P
WS15-17-P
WS18-02-O/P
WS18-09-P
WS18-22-P

210

WS20-11-P○WS28-11-P
WS29-06-O/P
WS29-08-P
WS31-12-P
WS11-03-P
Yoshimura, Teizo
WS02-22-P
Yoshimura, Tomoko WS09-06-O/P
Yoshinaga, Masanori WS14-18-P○WS22-01-O/P
Yoshino, Miya
WS06-15-P
WS27-15-P○WS07-21-P
Yoshino, Naoto
Yoshino, Yusuke
WS30-12-P
Yoshio, Sachiyo
WS23-13-O/P
Yoshioka, Yasuo
WS10-05-O/P
Yoshisato, Masayori WS12-14-P
Yoshitane, Hikari
WS30-11-P
Yoshitomi, Hiroyuki WS11-23-O/P
WS18-03-O/P
WS23-16-P
Yoshiyama, Takashi WS26-22-P
Yoshizaki, Kazuyuki ○WS23-08-O/P
WS25-11-P
Yuda, Junichiro
WS27-26-P
Yui, Katsuyuki
WS03-24-P
WS12-10-P
WS10-04-O/P
Yumura, Wako
WS31-09-P

Z
Zama, Noyuri
Zenda, Rie
Zhang, Baihao

WS02-15-P
WS14-07-P
S12-01
WS27-14-O/P
Zhang, Chenyang ○WS10-19-P
WS10-24-P
WS24-08-P
Zhang, Lillian F.
WS12-12-O/P
Zhang, Yu
S06-03○WS20-10-O/P
Zhao, Weiting
Zhao, Weiyang
WS18-23-P○WS01-09-P
Zheng, Jiawen○WS02-14-P
Zhu, BaohuiZhu, Jinfang
WS01-15-P
WS18-04-O/P
Ziegler, Steven F.
WS18-07-O/P
Zikherman, Julie
WS13-01-O/P
Zou, Chengcheng ○WS16-06-O/P
WS23-02-O/P

Acknowledgements
The Organizing Committee would like to express its appreciation to thefollowing organizations and individuals for their generous support.


Those listed as of Nov. 1, 2022.

Sponsorship » Platinum Sponsors» Gold Sponsors

211» Silver Sponsors» Bronze Sponsors

212

Seminars 
AbbVie GK

Novartis Pharma K.K.,

ASAHI KASEI Pharma

ONO PHARMACEUTICAL CO., LTD

Beckman Coulter K.K.

Otsuka Pharmaceutical Co., Ltd.

CHUGAI PHARMATICAL CO., LTD.

Pfizer Japan Inc

DAIICHI SANKYO COMPANY, LIMITEDSARTORIUS JAPAN K.K.

Eisai Co., Ltd.

Sony Corporation

Horizon Discovery K.K.

Specialty Care Medical, Sanofi K.K.

J anssen Pharmaceutical K.K.
Mitsubishi Tanabe Pharma Corporation

Standard BioTools K.K.
Takeda Pharmaceutical Company Limited

Leica Microsystems K.K.

Thermo Fisher Scientific

MSD K.K.

TOMY DIGITAL BIOLOGY CO., LTD.

Nippon Becton Dickinson Company, Ltd.

Exhibitors 
10x Genomics / SCRUM Inc.

Miltenyi Biotec K.K.

ACROBIOSYSTEMS CO.,LTD.

nacalai tesque

Air Liquide Japan G.K.

NanoString Technologies, Inc.

Axion BioSystmes Japan

NBRP Pathogenic eukaryotic microbes

Beckman Coulter K.K.

Nippon Becton Dickinson Company, Ltd.

CSCRIE CORPORATION

QuidelOrtho

DNA Chip Research Inc.

RIKEN BioResource Research Center

FUJIFILM Wako Pure Chemical Corporation

SARTORIUS JAPAN K.K.

GenScript Japan

Shanghai Model Organisms Center (USA), LLC

Horizon Discovery K.K.

Sino Biological Inc

InvivoGen Limited

Sony Corporation

IWAI CHEMICALS COMPANY LTD.

Standard BioTools K.K.

Japan SLC, Inc.

SYSMEX CORPORATION

Kiko Tech Co., Ltd.

TechnoSuruga Laboratory Co.,Ltd.

Kyudo Co., Ltd.

Thermo Fisher Scientific

Lonza K. K.

Tokyo Ohka Kogyo Co., Ltd.

Luminex Japan Corporation Ltd.

TOMY DIGITAL BIOLOGY CO., LTD.

Merck Ltd. Japan

Veritas Corporation

213

Advertisers 
Astellas Pharma Inc

Moderna Japan Co., Ltd.

EVIDENT CORPORATION

Nihon Servier Co., Ltd.

Gilead Sciences K.K. / EA Pharma Co., Ltd.

SYSMEX CORPORATIONMIYARISAN PHARMACEUTICAL CO. LTD.

Screen Advertisers 
10x Genomics / SCRUM Inc.

Tokyo Ohka Kogyo Co., Ltd.

HP Banner Sponsors 
Bio-Rad Laboratories K.K.

VectorBuilder Inc.

NIKON SOLUTIONS CO., LTD.

Session Sponsors Sony Corporation

Symposium 2's Sponsors 
Oxford University Press

Donors ／寄付 Janssen Pharmaceutical K.K.

杏林製薬株式会社

旭化成ファーマ株式会社

協和キリン株式会社

あすか製薬株式会社

クラシエ製薬株式会社

アステラス製薬株式会社

佐藤製薬株式会社

アストラゼネカ株式会社

沢井製薬株式会社

アルフレッサファーマ株式会社

住友ファーマ株式会社

栄研化学株式会社

参天製薬株式会社

エーザイ株式会社

株式会社三和化学研究所

大塚製薬株式会社

塩野義製薬株式会社

株式会社大塚製薬工場

ゼリア新薬工業株式会社

小野薬品工業株式会社

第一三共株式会社

科研製薬株式会社

大正製薬株式会社

キッセイ薬品工業株式会社

大鵬薬品工業株式会社
214

武田薬品工業株式会社

日本たばこ産業株式会社

田辺三菱製薬株式会社

日本ベーリンガーインゲルハイム株式会社

中外製薬株式会社

ニプロファーマ株式会社

株式会社ツムラ

バイエル薬品株式会社

帝人ファーマ株式会社

扶桑薬品工業株式会社

テルモ株式会社

ブリストル・マイヤーズ スクイブ株式会社

トーアエイヨー株式会社

丸石製薬株式会社

東和薬品株式会社

マルホ株式会社

鳥居薬品株式会社

株式会社ミノファーゲン製薬

日本化薬株式会社

Meiji Seika ファルマ株式会社

日本ケミファ株式会社

持田製薬株式会社

日本新薬株式会社

株式会社ヤクルト本社

日本製薬株式会社

ロート製薬株式会社

日本臓器製薬株式会社

わかもと製薬株式会社

Meeting/Program Sponsors ／開催助成、プログラム助成 
BioLegend, Inc.

Nakatani Foundation

Chugai Foundation for Innovative Drug Discovery Science

TERUMO LIFE SCIENCE FOUNDATION

Mochida Memorial Foundation for Medical and Pharmaceutical Research TOMY DIGITAL BIOLOGY CO.,LTD.

Cooperation ／協力 Kumamoto International Convention and Tourism Bureau

Supporting Members for The Japanese Society for Immunology 
A&E PLANNING CO., LTD.

KAKETSUKEN

Asahi Kasei Pharma Corporation

KM Biologics Co., Ltd.

BioLegend Japan KK

Miltenyi Biotec K.K.

Bio-Rad Laboratories K.K.

NACALAI TESQUE, INC.

Chugai Pharmaceutical Co., Ltd.

Nippon Becton Dickinson Company, Ltd.

DAIICHI SANKYO COMPANY, LIMITEDTAKARA BIO INC.

FUJIFILM Wako Pure Chemical Corporation

Takeda Pharmaceutical Company Limited

FUJIREBIO Inc.

Yakult Honsha Co.,Ltd.

Kaken Pharmaceutical Co.,Ltd.

YODOSHA CO., LTD.

215

日本免疫学会総会・学術集会記録
ISSN 0919−1984
2022 年 11 月 30 日
2022 年 11 月 30 日
発

行

製

作

第 51 巻

プログラム

印刷
発行

特定非営利活動法人 日本免疫学会〒 101-0024 東京都千代田区神田和泉町 1-4-2
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