主要原著論文_著書_総説リスト（尾﨑太郎）
原著論文（抜粋）
1. Heterologous expression of a polyketide synthase ACRTS2 in Aspregillus oryzae
produces host selective ACR-toxins: Co-production of minor metabolites
A. Kotani, T. Ozaki,* J. Takino, S. Mochizuki, K. Akimitsu, A. Minami,* H. Oikawa*
Biosci. Biotechnol. Biochem. 2022, 86, 287–293.
2. Biosynthetic Studies of Phomopsins Unveil Posttranslational Installation ofDehydroamino Acids by UstYa Family Proteins
K. Sogahata, T. Ozaki,* Y. Igarashi, Y. Naganuma, C. Liu, A. Minami,* H. Oikawa*Angew. Chem. Int. Ed. 2021, 60, 25729–25734; Angew. Chem. 2021, 133, 25933–25938.
3. Biochemistry‐guided prediction of the absolute configuration of fungal reduced
polyketides
J. Takino, A. Kotani, T. Ozaki, W. Peng, J. Yu, Y. Guo, S. Mochizuki, K. Akimitsu,
M. Hashimoto, T. Ye, A. Minami,* H. Oikawa*Angew. Chem. Int. Ed. 2021, 60, 23403–23411; Angew. Chem. 2021, 133, 23591–23599.
4. Biosynthesis of Cyclochlorotine: Identification of the Genes Involved in
Oxidative Transformations and Intramolecular O,N-Transacylation
Y. Jiang, T. Ozaki,* C. Liu, Y. Igarashi, Y. Ye, S. Tang, T. Ye, J. Maruyama, A.
Minami* and H. Oikawa*
Org. Lett., 2021, 23, 2616–2620.
5. Biosynthesis of Indole Diterpene Lolitrems: Radical‐Induced Cyclization of an
Epoxyalcohol Affording a Characteristic Lolitremane Skeleton
Y. Jiang, T. Ozaki, M. Harada, T. Miyasaka, H. Sato, K. Miyamoto, J. Kanazawa, C.
Liu, J. Maruyama, M. Adachi, A. Nakazaki, T. Nishikawa, M. Uchiyama, A.
Minami,* H. Oikawa*Angew. Chem. Int. Ed. 2020, 59, 17996–18002; Angew. Chem. 2020, 132, 18152–18158.

6. Oxidative Ring Contraction by a Multifunctional Dioxygenase Generates theCore Cycloocatadiene in the Biosynthesis of Fungal Dimeric Anhydride
Zopfiellin†
T. Shiina, †T. Ozaki, Y. Matsu, S. Nagamine, C. Liu, M. Hashimoto, *A. Minami
and *H. Oikawa (†equal contribution)
Org. Lett. 2020, 22, 1997–2001.
7. Acyltransferase That Catalyses the Condensation of Polyketide and Peptide
Moieties of Goadvionin Hybrid Lipopeptides
R. Kozakai, T. Ono, S. Hoshino, H. Takahashi, Y. Katsuyama, Y. Sugai, T. Ozaki, K.
Teramoto, K. Teramoto, K. Tanaka, I. Abe, S. Asamizu, and H. Onaka*Nat. Chem. 2020, 12, 869–877.
8. Minimal Lactazole Scaffold for In Vitro Thiopeptide Bioengineering
A. A. Vinogradov, M. Shimomura, Y. Goto,* T. Ozaki, S. Asamizu, Y. Sugai, H.
Suga,* and H. Onaka*Nat. Commun. 2020, 11, Article number: 2272.
9. Efficient Reconstitution of Basidiomycota Diterpene Erinacine Gene Cluster inAscomycota Host Aspergillus oryzae Based on Genomic DNA Sequences
C. Liu, A. Minami,* T. Ozaki, J. Wu, H. Kawagishi, J. Maruyama, and H. Oikawa*J. Am. Chem. Soc. 2019, 141, 15519–15523.
10. Ascomycete Aspergillus oryzae is an efficient expression host for production ofbasidiomycete terpenes by using genomic DNA sequences
S. Nagamine, C. Liu, J. Nishishita, T. Kozaki, K. Sogahata, Y. Sato, A. Minami,* T.
Ozaki, C. Schmidt-Dannert, J. Maruyama, H. Oikawa*Appl. Environ. Microbiol. 2019, 85, e00409–19.
11. Elucidation of Biosynthetic Pathway of a Plant Hormone Abscisic Acid in
Phytopathogenic Fungi
J. Takino, T. Kozaki, T. Ozaki, C. Liu, *A. Minami, and *H. Oikawa
Biosci. Biotechnol. Biochem. 2019, 83, 1642–1649.

12. Heterologous Production of Asperipin-2a: Proposal for Sequential Oxidative
Macrocyclization by a Fungi-specific DUF3328 Oxidase
Y. Ye, T. Ozaki,* M. Umemura, C. Liu, A. Minami, and H. Oikawa*
Org. Biomol. Chem. 2019, 17, 39–43.
13. Biosynthetic study of conidiation-inducing factor conidiogenone: heterologousproduction and cyclization mechanism of a key bifunctional diterpene synthase
T. Shiina, K. Nakagawa, Y. Fujisaki, T. Ozaki, C. Liu, T. Toyomasu, M. Hashimoto,
H. Koshino, A. Minami, H. Kawaide, and H. Oikawa*
Biosci. Biotechnol. Biochem. 2019, 83, 192–201.
14. Identification of the Common Biosynthetic Gene Cluster for Both Antimicrobial
Streptoaminals and Antifungal 5-Alkyl-1,2,3,4-tetrahydroquinolines
T. Ozaki, R, Sugiyama, M. Shimomura, S. Nishimura, S. Asamizu, Y. Katasuyama,
H. Kakeya,* and H. Onaka*Org. Biomol. Chem. 2019, 17, 2370–2378.
15. Total Biosynthesis of Brassicicenes: Identification of a Key Enzyme for Skeletal
Diversification
A. Tazawa, Y. Ye, T. Ozaki,* C. Liu, Y. Ogasawara, T. Dairi, Y. Higuchi, N. Kato, K.
Gomi, A. Minami, and H. Oikawa*
Org. Lett., 2019, 20, 6178–6182.
16. Unveiling Biosynthesis of the Phytohormone Abscisic Acid in Fungi:
Unprecedented Mechanism of Core Scaffold Formation Catalyzed by an
Unusual Sesquiterpene Synthase
J. Takino, T. Kozaki, Y. Sato, C. Liu, T. Ozaki, A. Minami,* and H. Oikawa*J. Am. Chem. Soc. 2018, 140, 12392–12395.
17. Enzymatic Formation of a Skipped Methyl‐Substituted Octaprenyl Side Chainof Longestin (KS‐505a): Involvement of Homo‐IPP as a Common Extender Unit†
T. Ozaki, †S. S. Sandip, L. Gao, R. Okuizumi, C. Liu, Y. Ogasawara, X. Lei, T. Dairi,
A. Minami,* and H. Oikawa* (†equal contribution)
Angew. Chem. Int. Ed. 2018, 57, 6629–6632; Angew. Chem. 2018, 130, 6739–6742.

18. Identification of Novel Sesterterpenes by Genome Mining of Phytopathogenic
Fungi Phoma and Colletotrichum sp.
L. Gao, K. Narita, T. Ozaki,* Kumakura, P. Gan, A. Minami, C. Liu, X. Lei, K.
Shirasu and H. Oikawa*
Tetrahedron Lett. 2018, 59, 1136–1139.
19. Dissection of goadsporin biosynthesis by in vitro reconstitution leading todesigner analogues expressed in vivo.
T. Ozaki,†K. Yamashita,† Y. Goto, M. Shimomura, S. Hayashi, S. Asamizu, Y. Sugai,
H. Ikeda, H. Suga,* and H. Onaka* (†equal contribution)Nat. Commun. 2017, 8, Article number: 14207.
20. Insights into the Biosynthesis of Dehydroalanines in Goadsporin.
T. Ozaki, Y. Kurokawa, S. Hayashi, N. Oku, S. Asamizu, Y. Igarashi, and H. Onaka*
ChemBioChem 2016, 17, 218–223.
21. Genome Mining Reveals a Minimum Gene Set for the Biosynthesis of 32Membered Macrocyclic Thiopeptides Lactazoles.
S. Hayashi, T. Ozaki, S. Asamizu, H. Ikeda, S. Ōmura, N. Oku, Y. Igarashi, H.
Tomoda, and H. Onaka*
Chem. Biol. 2014, 21, 679–688.
22. Cyclolavandulyl Skeleton Biosynthesis via both Condensation and Cyclization
Catalyzed by an Unprecedented Member of the cis-Isoprenyl Diphosphate
Synthase Superfamily.
T. Ozaki, P. Zhao, T. Shinada, M. Nishiyama, and T. Kuzuyama*J. Am. Chem. Soc. 2014, 136, 4837–4840.
23. Novel Tryptophan Metabolism by a Potential Gene Cluster That Is Widely
Distributed among Actinomycetes
T. Ozaki, M. Nishiyama, and T. Kuzuyama*
J. Biol. Chem. 2013, 288, 9946–9956.
24. NovQ is a Prenyltransferase Capable of Catalyzing the Addition of aDimethylallyl Group to Both Phenylpropanoids and Flavonoids
T. Ozaki, S. Mishima, M. Nishiyama, and T. Kuzuyama*
J. Antibiot.2009, 62, 385–392.

著書
英語
1.

C. Liu, A. Minami, T. Ozaki, and H. Oikawa, “Biosynthesis of Indole Diterpenes”
In Comprehensive Natural Products III: Chemistry and Biology; Liu, H.-W., Begley,T., Eds.; Elsevier: Oxford, Vol. 2, Elsevier, Chapter 16, pp. 446–466 (2020)

2.

A. Minami, T. Ozaki, C. Liu, H. Oikawa, “Sesterterpene Biosynthesis: Cyclization
Mechanisms and Oxidative Modifications” In Comprehensive Natural Products III:Chemistry and Biology; Liu, H.-W., Begley, T., Eds.; Elsevier: Oxford, Vol. 1,Elsevier, Chapter 17, pp. 553–576 (2020)

日本語
1.

酵母菌・麹菌・乳酸菌の産業応用展開 (分担執筆)
南 篤志、劉 成偉、尾﨑太郎、及川英秋
シーエムシー出版

総説・解説英語
1. Cyclopentane-forming di/sesterterpene synthases: widely distributed enzymes
in bacteria, fungi, and plants
A. Minami,* T. Ozaki, C. Liu, and H. Oikawa*Nat. Prod. Rep. 2018, 35, 1330–1346.
日本語
1. 担子菌未利用生合成遺伝子を活用した有用物質生産法の開発
南篤志, 尾﨑太郎, 及川英秋
ファインケミカル, 2021, 50, No. 4, 25–32.
2.

糸状菌由来生物活性天然物の全生合成
南篤志, 尾﨑太郎, 及川英秋
ファインケミカル,2020, 49, No. 3, 19–24.

3.

糸状菌による植物ホルモンアブシジン酸の生合成・新奇な環化酵素の発見
南篤志, 尾﨑太郎, 劉成偉, 及川英秋
バイオサイエンスとインダストリー, 2019, 77, 136–138.

4.

糸状菌テルペン環化酵素遺伝子のゲノムマイニングによる新規天然物の生産
南篤志、尾崎太郎、劉成偉、及川英秋
バイオサイエンスとインダストリー 2018, 76, 20–25.

5.

多様なリボゾーム翻訳後修飾ペプチド（RiPPs）の試験管内生合成
尾崎太郎、後藤佑樹、尾仲宏康
バイオサイエンスとインダストリー 2017, 75, 524–526.

6.

天然ペプチド骨格の合理的な設計手法の開発
尾崎太郎、菅裕明、尾仲宏康
酵素工学ニュース Vol. 78, 10–13（2017）7.

リボソームが作るペプチド系天然物の生合成
尾崎太郎
化学と工業 2017, 70, 882.

8.

翻訳後修飾による D-アミノ酸の導入
尾崎太郎
化学 2017, 72, 59–60.

9.

転移 RNA のいろいろな機能
尾崎太郎
生物工学会誌 2017, 95, 206.

10. 構造多様性を創出する新奇テルペノイド合成酵素の発見
尾崎太郎、葛山智久
バイオサイエンスとインダストリー 2014, 72, 412–414.
11. 新しいトリプトファン代謝経路を放線菌から発見
尾崎太郎、葛山智久
化学と生物 2014, 52, 148–150.