Nihonbashi Dia Building, 1-19-1, Nihonbashi, Chuo-ku, Tokyo 103-0027, JAPAN
Telephone: +81-3-5290-2810 Facsimile: +81-3-3231-1183
Date Issued: 2023.3.14

Innovation in Resistance Management:
VECTRONTM T500, a new vector control product,is prequalified by The World Health Organization (WHO)
Mitsui Chemicals Agro, Inc. (Tokyo; President & CEO: OZAWA Satoshi) today
announce that their Indoor Residual Spray (IRS) for malaria control,
VECTRONTM T500, has been prequalified by the WHO*1).

Mosquitoes in Bugesera district, Rwanda.
Photographed by Mitsui Chemicals Agro.

IRS village trial in Lagos, Nigeria.
Photographed by IVCCVECTRONTM T500 is a new IRS product containing TENEBENALTM, the world’s firstmeta-diamide active ingredient (IRAC Group 30) developed by Mitsui Chemicals Agrowhich has a different mode of action from existing vector control products.
VECTRONTM T500 will support the rotation of insecticides in line with best practiceinsecticide resistance management, which is critical to preserve the long-term efficacy
of vector control tools. VECTRONTM T500 has outstanding efficacy against malariavector mosquitoes including strains and populations resistant to pyrethroids and someother insecticides. It works on a variety of types of wall surfaces, including mud, andshows long residual efficacy.
VECTRONTM T500 is non-repellent, odorless and stainless formulation with low
mammalian acute toxicity, and is supplied in easy-to-handle 50g aluminum sachets.
Mitsui Chemicals Agro will launch VECTRONTM T500 in sub-Saharan African countries
from 2023 in line with locally required conditions of use.

OZAWA says: “Mitsui Chemicals Agro is an R&D driven chemical company, that has
been developing malaria vector control products to save human lives. Our mission is toprovide solutions to health challenges through the development and deployment ofinnovative, high-quality products. We are committed to malaria eradication and are
excited about the launch of VECTRONTM T500. We appreciate the support of all ourstakeholders and partners in reaching this important milestone.”
Justin McBeath CEO of IVCC added: “IVCC was established with a mission to work withpartners, such as Mitsui Chemicals Agro, to accelerate the availability of new publichealth insecticides which will help address the significant threat of insecticide resistancein malaria vectors. We are delighted to have supported Mitsui Chemicals Agro on theirachievement of the PQ-listing of this important breakthrough product which represents
another significant milestone in the fight against malaria.”

Notes to Editors
Mitsui Chemicals Agro, Inc.
Mitsui Chemicals Agro is an R&D driven company that is a global provider of solutions
by high-quality products and services in the agrochemicals field. The company has ahistory of about 100 years beginning with the manufacture and release of the firstsynthetic agrochemical in Japan. Mitsui Chemicals Agro has been contributing humanhealth and comfortable life through PPM (Professional Pest Management) business,providing unique active ingredients and formulated products. Mitsui Chemicals Agro is
100% subsidiary of Mitsui Chemicals (Tokyo: 4183, ISIN: JP3888300005) which has anannual sale of 1,612 billion yen in the fiscal year ending March 2022.
IVCC
IVCC is the only Product Development Partnership (PDP) working in vector control.
IVCC was established in 2005, through an initial $50 million grant to the Liverpool
School of Tropical Medicine (LSTM) from the Bill & Melinda Gates Foundation and hassince provided ongoing support for IVCC activities. As a registered charity in the UK,
IVCC is also funded by UK Aid, USAID and the Swiss Agency for Development andCooperation to work with stakeholders to facilitate the development of novel andimproved public health insecticides and formulations to combat the rapidly growing
problem of insecticide resistance. In addition, IVCC is also funded by Unitaid and theGlobal Fund to implement catalytic market access projects, such as NgenIRS and theNew Nets Project which support the rapid and scaled deployment of innovative vector
control interventions. IVCC brings together partners from industry, the public sector
and academia to create new solutions to prevent disease transmission. By focusing
resources and targeting practical scientific solutions we accelerate the process frominnovation to impact.

<Reference>*1) List of WHO Prequalified Vector Control Products
https://extranet.who.int/pqweb/vector-control-products/prequalified-product-list⚫ VECTRONTM T500 : https://www.vectront500.com/⚫ Mitsui Chemicals Agro, Inc.: https://www.mitsui-agro.com/en/⚫ IVCC : https://www.ivcc.com/<Contacts for inquiries about VECTRONTM T500>
International Business Div. Mitsui Chemicals Agro, Inc.
E-mail; MCAG-Vectron@mitsuichemicals.com<Contacts for inquiries about this project>
Corporate Communication Div. Mitsui Chemicals, Inc.
URL; https://form.mitsuichemicals.com/corporate/cc_pr_csr_en