SAFETY DATA SHEET

according to Regulation (EC) No. 1907/2006

Immersol 518 F / 37°C

Version 4.0
Revision date: 27.07.2023

Material: 000000-0559-056
Date of last issue: 27.07.2023

SECTION 1: Identification of the substance/mixture and of the company/undertaking
1.1 Product identifier
Product name
Unique Formula Identifier
(UFI)

:

Immersol(TM) 518 F / 37 °C:

6S20-C0W9-F00N-01PF

1.2 Relevant identified uses of the substance or mixture and uses advised against
Use of the Sub: Life Sciences, Research and Development
stance/Mixture
Industrial and professional use
Immersion oil for fluorescence-microscopy, halogen-free, lowfluorescence
1.3 Details of the supplier of the safety data sheet
Manufacturer/supplier:

Address:

Telephone:Carl Zeiss Jena GmbH
Oberkochen location
Carl-Zeiss-Straße 22
D-73447 Oberkochen+49 7364 20-0

Technical Information
TelephoneTelefax:::

Chemical and material engineering+49 7364 20-4599+49 7364 20-4521

Product Safety
E-mail address::

Chemical and material engineering
SDS@zeiss.com

1.4 Emergency telephone number
Poisening Control Center:+49 551 19240 (24 hours)

SECTION 2: Hazards identification
2.1 Classification of the substance or mixture
Classification (REGULATION (EC) No 1272/2008)
Skin irritation, Category 2
H315: Causes skin irritation.
Long-term (chronic) aquatic hazard, CatH411: Toxic to aquatic life with long lasting effects.
egory 22.2 Label elements
Labelling (REGULATION (EC) No 1272/2008)

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SAFETY DATA SHEET

according to Regulation (EC) No. 1907/2006

Immersol 518 F / 37°C

Version 4.0
Revision date: 27.07.2023

Material: 000000-0559-056
Date of last issue: 27.07.2023

Hazard pictograms:

Signal word:

Warning

Hazard statements

:

H315
H411

Precautionary statements:

Prevention:
P273 Avoid release to the environment.
P280 Wear protective gloves.

Causes skin irritation.
Toxic to aquatic life with long lasting effects.

Response:
P302 + P352
water.

IF ON SKIN: Wash with plenty of soap and2.3 Other hazards
None known.

SECTION 3: Composition/information on ingredients
3.2 Mixtures
Chemical nature:

Components
Chemical name

Adipic acid-di(8-methyl-tricyclo(5.2.1.0.2.6.) decane) ester
Succinic acid-di(8-methyl-tricyclo(5.2.1.0.2.6.) decane) ester

Halogen-free immersion oil based on ester oil.
CAS-No.
EC-No.
Index-No.
Registration number
195371-10-9
430-080-6
01-0000017636-64
195371-13-2

Bis (isopropyl) naphthalene

38640-62-9
254-052-6
01-2119565150-48
For explanation of abbreviations see section 16.

Classification

Concentration(% w/w)

Skin Irrit. 2; H315

30 - 35

Skin Irrit. 2; H315

25 - 30

Asp. Tox. 1; H304
Aquatic Chronic 1;
H410

15 - 20

SECTION 4: First aid measures
4.1 Description of first aid measures
General advice: Remove and wash contaminated clothing before re-use.
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SAFETY DATA SHEET

according to Regulation (EC) No. 1907/2006

Immersol 518 F / 37°C

Version 4.0
Revision date: 27.07.2023

Material: 000000-0559-056
Date of last issue: 27.07.2023

If inhaled:

In the case of inhalation of aerosol/mist consult a physician if
necessary.

In case of skin contact:

Wash off with soap and plenty of water.
In the case of skin irritation or allergic reactions see a physician.

In case of eye contact:

Immediately flush eye(s) with plenty of water.
If eye irritation persists, consult a specialist.

If swallowed:

Rinse mouth.
Do not give anything to drink or eat.
Do NOT induce vomiting.
Get medical attention.

4.2 Most important symptoms and effects, both acute and delayed
Symptoms: The most important known symptoms and effects are described in section 2 and / or section 11.
4.3 Indication of any immediate medical attention and special treatment needed
Treatment: No information available.

SECTION 5: Firefighting measures
5.1 Extinguishing media
Suitable extinguishing media

Unsuitable extinguishing
media

:

Carbon dioxide (CO2)
Dry chemical
Foam
Sand
Water spray jet:

High volume water jet

5.2 Special hazards arising from the substance or mixture
Specific hazards during fire- : In case of fire formation of carbonoxides and other toxic gasfighting
es/vapors is possible.
5.3 Advice for firefighters
Special protective equipment
for firefighters
Further information:

In the event of fire, wear self-contained breathing apparatus.

:

Use water spray to cool unopened containers.
Avoid extinguishing water reaching water, ground water or
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SAFETY DATA SHEET

according to Regulation (EC) No. 1907/2006

Immersol 518 F / 37°C

Version 4.0
Revision date: 27.07.2023

Material: 000000-0559-056
Date of last issue: 27.07.2023

sewage system.

SECTION 6: Accidental release measures
6.1 Personal precautions, protective equipment and emergency procedures
Personal precautions: Avoid contact with skin, eyes and clothing.
Ensure adequate ventilation.
Risk of slipping because of leaked / spilled product6.2 Environmental precautions
Environmental precautions:

Prevent discharge into sewerage system, soil or aquatic environment.

6.3 Methods and material for containment and cleaning up
Methods for cleaning up: Soak up with inert absorbent material.
Clean contaminated surface thoroughly.
6.4 Reference to other sections
Adequate disposal, For disposal considerations see section 13.

SECTION 7: Handling and storage
7.1 Precautions for safe handling
Advice on safe handling:
Advice on protection against :fire and explosion

Avoid contact with skin and eyes.
Keep away from open flames, hot surfaces and sources ofignition.

7.2 Conditions for safe storage, including any incompatibilities
Requirements for storage: Store at room temperature in the original container. Keepareas and containers
tightly closed.
Advice on common storage

7.3 Specific end use(s)Specific use(s):Keep away from food and drink.
Do not mix with other immersion liquids.

:

Apart from the uses mentioned in section 1 no other specificuses are intended.

SECTION 8: Exposure controls/personal protection
8.1 Control parametersNone.
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SAFETY DATA SHEET

according to Regulation (EC) No. 1907/2006

Immersol 518 F / 37°C

Version 4.0
Revision date: 27.07.2023

Material: 000000-0559-056
Date of last issue: 27.07.2023

8.2 Exposure controls
Personal protective equipment
Eye/face protection: Avoid contact with eyes, if necessary wear eye protection.
Hand protection
Remarks

Skin and body protection
Respiratory protection
Protective measures:

Avoid contact with skin. Use protective gloves which havebeen adapted to the respective purpose and are appropriately resistant to chemicals (DIN EN 374). Ask the glove supplierfor the penetration time of the glove material.
closed work clothing
Not required; except in case of aerosol formation.
Take off all contaminated clothing immediately.
Wash hands before breaks and at the end of workday.
Preventive skin protection:::

SECTION 9: Physical and chemical properties
9.1 Information on basic physical and chemical properties
Physical state: liquid
Colour: colourlessOdour: slight, aromatic
Boiling point/boiling range: > 250 °C
Flash point:

216 °C
Method: open cup

pH:

Not applicable

Viscosity
Viscosity, kinematic:

236 mm²/s (40 °C)
Method: DIN 51562

Solubility(ies)
Water solubility:

insoluble

Density:

1.019 g/cm³ (20 °C)
Method: DIN 51757

9.2 Other information
No data available

SECTION 10: Stability and reactivity
10.1 Reactivity
No data available
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SAFETY DATA SHEET

according to Regulation (EC) No. 1907/2006

Immersol 518 F / 37°C

Version 4.0
Revision date: 27.07.2023

Material: 000000-0559-056
Date of last issue: 27.07.2023

10.2 Chemical stability
No decomposition if stored and applied as directed.
10.3 Possibility of hazardous reactions
Hazardous reactions: None known.
10.4 Conditions to avoid
Conditions to avoid:

Protect from heat, heating sources and direct insolation.

10.5 Incompatible materials
Materials to avoid:

Oxidizing agents

10.6 Hazardous decomposition products
Hazardous decomposition: No decomposition if used as directed.
products

SECTION 11: Toxicological information
11.1 Information on hazard classes as defined in Regulation (EC) No 1272/2008
Acute toxicity
Components:
Adipic acid-di(8-methyl-tricyclo (5.2.1.0.2.6.) decane) ester:
Acute oral toxicity: LD50 (Rat): > 2,000 mg/kg
Method: Directive 96/54/EG, B.1
Acute dermal toxicity:

Bis (isopropyl) naphthalene:
Acute oral toxicity:

LD50 (Rabbit): > 2,000 mg/kg
Method: OECD Test Guideline 402

LD50 (Rat): > 4,000 mg/kg
Method: OECD Test Guideline 401

Acute inhalation toxicity:

LC50 (Rat): > 5.6 mg/l
Method: OECD Test Guideline 403

Acute dermal toxicity:

LD50 (Rat): > 4,000 mg/kg
Method: OECD Test Guideline 402:

Irritating to skin.

Skin corrosion/irritation
Product:
Remarks

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SAFETY DATA SHEET

according to Regulation (EC) No. 1907/2006

Immersol 518 F / 37°C

Version 4.0
Revision date: 27.07.2023

Date of last issue: 27.07.2023

Components:
Adipic acid-di(8-methyl-tricyclo (5.2.1.0.2.6.) decane) ester:Species: Rabbit
Exposure time
: 4hMethod: Directive 92/69/EWG, B.4
Result: Skin irritation
Bis (isopropyl) naphthalene:
Species:
Method:Result:RabbitOECD Test Guideline 404
No skin irritation

Serious eye damage/eye irritation
Product:
Remarks

Material: 000000-0559-056:

May irritate eyes.

Components:
Adipic acid-di(8-methyl-tricyclo (5.2.1.0.2.6.) decane) ester:Species: RabbitMethod: Directive 92/69/EWG, B.5
Result: No eye irritation
Bis (isopropyl) naphthalene:
Species:
Method:Result:RabbitOECD Test Guideline 405
No eye irritation

Respiratory or skin sensitisation
Components:
Adipic acid-di(8-methyl-tricyclo (5.2.1.0.2.6.) decane) ester:Species: guinea-pig
Method: Richtlinie 96/54/EG, B.6
Result: Not sensitizing.
Bis (isopropyl) naphthalene:
Species:
Method:Result:guinea-pig
OECD Test Guideline 406
Not sensitizing.

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SAFETY DATA SHEET

according to Regulation (EC) No. 1907/2006

Immersol 518 F / 37°C

Version 4.0
Revision date: 27.07.2023

Material: 000000-0559-056
Date of last issue: 27.07.2023

Germ cell mutagenicity
Product:
Germ cell mutagenicity- Assessment:

No data available

Components:
Adipic acid-di(8-methyl-tricyclo (5.2.1.0.2.6.) decane) ester:Germ cell mutagenicity- As: Cytogenetic test (chromosome aberration), chinese hamster:
sessment
No reference to mutagenic effects. (OECD TG 473)
Ames-Test, salmonella typhimurium: No reference to mutagenic effects. (EEC B 14)
Bis (isopropyl) naphthalene:
Germ cell mutagenicity- As:sessment

negative

Carcinogenicity
Product:
Carcinogenicity - Assessment:

No data available

Components:
Bis (isopropyl) naphthalene:
Carcinogenicity - Assess:ment

negative

Reproductive toxicity
Product:
Reproductive toxicity - Assessment:

No data available

Components:
Bis (isopropyl) naphthalene:
Reproductive toxicity - As:sessment

negative
negative

STOT - single exposure
Product:
Remarks:

No data available

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SAFETY DATA SHEET

according to Regulation (EC) No. 1907/2006

Immersol 518 F / 37°C

Version 4.0
Revision date: 27.07.2023

Material: 000000-0559-056
Date of last issue: 27.07.2023

STOT - repeated exposure
Product:
Remarks:

No data available

Components:
Adipic acid-di(8-methyl-tricyclo (5.2.1.0.2.6.) decane) ester:
Repeated dose toxicity : NOAEL oral, rat: 500 mg/kg (Testing period: 28 d, Subsequent
Assessment
observation period: 48 d, OECD TG 407)
Aspiration toxicity
Product:
The classification criteria are not met by the available data.
11.2 Information on other hazards
Further information
Product:
Remarks:

No data is available on the product itself.
The product is classified in accordance with EC directive /regulation.
Handle in accordance with good industrial hygiene and safety
practice.

Components:
Adipic acid-di(8-methyl-tricyclo (5.2.1.0.2.6.) decane) ester:
Remarks: The product should be handled with the care usual when dealing with chemicals.

SECTION 12: Ecological information
12.1 Toxicity
Product:
Ecotoxicology Assessment
Chronic aquatic toxicity:

Toxic to aquatic life with long lasting effects.

Components:
Adipic acid-di(8-methyl-tricyclo (5.2.1.0.2.6.) decane) ester:
Toxicity to fish
: LC50 (Cyprinus carpio): > 5.4 mg/l
Exposure time: 96 h
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SAFETY DATA SHEET

according to Regulation (EC) No. 1907/2006

Immersol 518 F / 37°C

Version 4.0
Revision date: 27.07.2023

Material: 000000-0559-056
Date of last issue: 27.07.2023

Method: Directive 92/69/EWG C.1
LC0 (Cyprinus carpio): >= 5.40 mg/l
Exposure time: 96 h
Method: Directive 92/69/EWG C.1
Toxicity to daphnia and other :aquatic invertebrates

EC50 (Daphnia (water flea)): > 6.1 mg/l
Exposure time: 48 h
Method: Directive 92/69/EWG C.2
EC0 (Daphnia (water flea)): >= 6.10 mg/l
Exposure time: 48 h
Method: Directive 92/69/EWG C.2
NOEC (Daphnia (water flea)): 1.6 mg/l
Exposure time: 504 h
Analytical monitoring: yes
Remarks: chronic toxicity to daphnia

Toxicity to algae/aquaticplants:

EC50 (Desmodesmus subspicatus (green algae)): > 3.6 mg/l
Exposure time: 72 h
Method: Directive 92/69/EWG C.3
NOEC (Desmodesmus subspicatus (green algae)): >= 3.6
mg/l
Exposure time: 72 h
Method: Directive 92/69/EWG C.3

Toxicity to microorganisms:

Bis (isopropyl) naphthalene:
Toxicity to fish:

Toxicity to daphnia and other :aquatic invertebrates

EC10 (activated sludge): > 1,000 mg/l
Exposure time: 3 hMethod: EG L133/118 (5.88)
Remarks: to respiration inhibition test applies EC50

LC0 (Fish): 0.5 mg/l
Exposure time: 96 h
Method: OECD Test Guideline 203
LL50 (Daphnia (water flea)): 1.7 mg/l
Exposure time: 48 h
Method: OECD Test Guideline 202
EC0 (Daphnia (water flea)): 0.16 mg/l
Exposure time: 48 h
Method: DIN 38412
NOEC (Daphnia (water flea)): 13 mg/l
Exposure time: 21 DAY
Method: OECD Test Guideline 202
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SAFETY DATA SHEET

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Immersol 518 F / 37°C

Version 4.0
Revision date: 27.07.2023
Toxicity to algae/aquaticplantsMaterial: 000000-0559-056
Date of last issue: 27.07.2023:

EC0 (algae): 0.15 mg/l
Exposure time: 72 h
Method: OECD Test Guideline 201

12.2 Persistence and degradability
Components:
Adipic acid-di(8-methyl-tricyclo (5.2.1.0.2.6.) decane) ester:
Biodegradability: Result: Not readily biodegradable.
Biodegradation: 13 %Exposure time: 28 days
Method: Modified Sturm Test
Bis (isopropyl) naphthalene:
Biodegradability:

Result: Not readily biodegradable.

Physico-chemical removability

Remarks: May be separated mechanically in waste water
plants.

:12.3 Bioaccumulative potential
Components:
Adipic acid-di(8-methyl-tricyclo (5.2.1.0.2.6.) decane) ester:Partition coefficient: n: log Pow: 8.9 (25 °C)
octanol/water
Method: Directive 92/69/EWG A.8
Bis (isopropyl) naphthalene:
Partition coefficient: n:octanol/waterlog Pow: > 4

12.4 Mobility in soil
Components:
Adipic acid-di(8-methyl-tricyclo (5.2.1.0.2.6.) decane) ester:
Mobility: Remarks: KOC: 50.000 (water, soil), (Method: OECD TG 121)
12.5 Results of PBT and vPvB assessment
Not relevant
12.6 Endocrine disrupting properties
No data available
12.7 Other adverse effects
Product:
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SAFETY DATA SHEET

according to Regulation (EC) No. 1907/2006

Immersol 518 F / 37°C

Version 4.0
Revision date: 27.07.2023
Additional ecological information

Material: 000000-0559-056
Date of last issue: 27.07.2023:

No data is available on the product itself.
The product is classified in accordance with EC directive /regulation.
Do not discharge into sewerage system, surface water or soil.
Adequate disposal

Components:
Adipic acid-di(8-methyl-tricyclo (5.2.1.0.2.6.) decane) ester:
Additional ecological infor: Do not discharge into sewerage system, surface water or soil.
mationAdequate disposal
Bis (isopropyl) naphthalene:
Additional ecological infor:
mation

Do not discharge into sewerage system, surface water or soil.

SECTION 13: Disposal considerations
13.1 Waste treatment methods
Product:

In accordance with local and national regulations.

Contaminated packaging:

Dispose of as unused product.
Offer rinsed packaging material to local recycling facilities.

SECTION 14: Transport information
14.1 UN number or ID number
ADR:

UN 3082

IMDG:

UN 3082

IATA:

UN 3082ADR:

ENVIRONMENTALLY HAZARDOUS SUBSTANCE, LIQUID,
N.O.S.
(Bis (isopropyl) naphthalene, mixture)

IMDG

:

ENVIRONMENTALLY HAZARDOUS SUBSTANCE, LIQUID,
N.O.S.
(BIS (ISOPROPYL) NAPHTHALENE, MIXTURE)

IATA

:

Environmentally hazardous substance, liquid, n.o.s.
(Bis (isopropyl) naphthalene, mixture)

14.2 UN proper shipping name14.3 Transport hazard class(es)Class

Subsidiary risks
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SAFETY DATA SHEET

according to Regulation (EC) No. 1907/2006

Immersol 518 F / 37°C

Version 4.0
Revision date: 27.07.2023

Material: 000000-0559-056
Date of last issue: 27.07.2023

ADR

:

9

IMDG

:

9

IATA

:

9

ADR
Packing groupClassification CodeHazard Identification Number
LabelsTunnel restriction code

:
:
:
:
:

III
M6
90
9
(E)

IMDG
Packing group
LabelsEmS Code

:
:
:

III
9
F-A, S-F

IATA (Cargo)
Packing group
Labels::III
Miscellaneous

IATA (Passenger)
Packing group
Labels::III
Miscellaneous

ADR
Environmentally hazardous

:

no

IMDG
Marine pollutant:

no14.4 Packing group

14.5 Environmental hazards

14.6 Special precautions for user
The transport classification(s) provided herein are for informational purposes only, and solely
based upon the properties of the unpackaged material as it is described within this Safety Data
Sheet. Transportation classifications may vary by mode of transportation, package sizes, and variations in regional or country regulations.
14.7 Maritime transport in bulk according to IMO instruments
Not applicable for product as supplied.

SECTION 15: Regulatory information
15.1 Safety, health and environmental regulations/legislation specific for the substance or mixture
Seveso III: Directive 2012/18/EU of the European Parliament and of the Council on the

1.3.2 E2

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SAFETY DATA SHEET

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Immersol 518 F / 37°C

Version 4.0
Revision date: 27.07.2023

Material: 000000-0559-056
Date of last issue: 27.07.2023

control of major-accident hazards involving
dangerous substances.
Other regulations:
Follow Directive 94/33/EC on the protection of young people at work and its national implementations.
Follow Directive 92/85/EC on the protection of pregnant workers and workers who have recently given birth or are breastfeeding, and its national implementations.
15.2 Chemical safety assessment
Not required.

SECTION 16: Other information
Full text of H-Statements
H304
H315
H410

:
:
:

May be fatal if swallowed and enters airways.
Causes skin irritation.
Very toxic to aquatic life with long lasting effects.

Full text of other abbreviations
Aquatic Chronic: Long-term (chronic) aquatic hazard
Asp. Tox.
: Aspiration hazard
Skin Irrit.
: Skin irritation
ADN - European Agreement concerning the International Carriage of Dangerous Goods by Inland
Waterways; ADR - Agreement concerning the International Carriage of Dangerous Goods by
Road; AIIC - Australian Inventory of Industrial Chemicals; ASTM - American Society for the Testing of Materials; bw - Body weight; CLP - Classification Labelling Packaging Regulation; Regulation (EC) No 1272/2008; CMR - Carcinogen, Mutagen or Reproductive Toxicant; DIN - Standardof the German Institute for Standardisation; DSL - Domestic Substances List (Canada); ECHA European Chemicals Agency; EC-Number - European Community number; ECx - Concentration
associated with x% response; ELx - Loading rate associated with x% response; EmS - Emergency Schedule; ENCS - Existing and New Chemical Substances (Japan); ErCx - Concentration associated with x% growth rate response; GHS - Globally Harmonized System; GLP - Good Laboratory Practice; IARC - International Agency for Research on Cancer; IATA - International Air
Transport Association; IBC - International Code for the Construction and Equipment of Ships carrying Dangerous Chemicals in Bulk; IC50 - Half maximal inhibitory concentration; ICAO - International Civil Aviation Organization; IECSC - Inventory of Existing Chemical Substances in China;
IMDG - International Maritime Dangerous Goods; IMO - International Maritime Organization; ISHL
- Industrial Safety and Health Law (Japan); ISO - International Organisation for Standardization;
KECI - Korea Existing Chemicals Inventory; LC50 - Lethal Concentration to 50 % of a test population; LD50 - Lethal Dose to 50% of a test population (Median Lethal Dose); MARPOL - International Convention for the Prevention of Pollution from Ships; n.o.s. - Not Otherwise Specified;NO(A)EC - No Observed (Adverse) Effect Concentration; NO(A)EL - No Observed (Adverse) Effect Level; NOELR - No Observable Effect Loading Rate; NZIoC - New Zealand Inventory ofChemicals; OECD - Organization for Economic Co-operation and Development; OPPTS - Officeof Chemical Safety and Pollution Prevention; PBT - Persistent, Bioaccumulative and Toxic substance; PICCS - Philippines Inventory of Chemicals and Chemical Substances; (Q)SAR - (Quanti14 / 15

SAFETY DATA SHEET

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Immersol 518 F / 37°C

Version 4.0
Revision date: 27.07.2023

Material: 000000-0559-056
Date of last issue: 27.07.2023

tative) Structure Activity Relationship; REACH - Regulation (EC) No 1907/2006 of the European
Parliament and of the Council concerning the Registration, Evaluation, Authorisation and Restriction of Chemicals; RID - Regulations concerning the International Carriage of Dangerous
Goods by Rail; SADT - Self-Accelerating Decomposition Temperature; SDS - Safety Data Sheet;
SVHC - Substance of Very High Concern; TCSI - Taiwan Chemical Substance Inventory; TECI Thailand Existing Chemicals Inventory; TRGS - Technical Rule for Hazardous Substances; TSCA
- Toxic Substances Control Act (United States); UN - United Nations; vPvB - Very Persistent andVery Bioaccumulative
Further information
Other information
Sources of key data used tocompile the Safety Data
Sheet

:
:

Relevant changes to the previous version are symbolized byvertical bars at the left edge.
Reg. 1272/2008, Annex VI
TRGS 900
TRGS 903
International dangerous goods regulations
Supplier details

The information in this safety sheet is based on the data available at the time of compilation andis intended to describe the product with respect to the precautions to be taken in its use. This information is provided without any guarantee of the properties specified.
MT / EN

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