The Proposition 65 List
当社製品には、アメリカにてカリフォルニア州法「プロポジション65」に定められた表示をしております。
以下に、製品表示を補完するため対象物質リストを掲載いたします。

Chemical Name

Abiraterone acetate

Type of Toxicity (Date Listed)
Developmental Toxicity(04/08/2016)
Female Reproductive Toxicity(04/08/2016)
Male Reproductive Toxicity(04/08/2016)

Acetaldehyde

Cancer (04/01/1988)

Acetamide

Cancer (01/01/1990)

Acetazolamide

Developmental Toxicity(08/20/1999)

Acetochlor

Cancer (01/01/1989)

Acetohydroxamic Acid

Developmental Toxicity(04/01/1990)

2-Acetylaminofluorene

Cancer (07/01/1987)

Acifluorfen Sodium

Cancer (01/01/1990)
Cancer (01/01/1990)
Developmental Toxicity(02/25/2011)

Acrylamide

Acrylonitrile

Male Reproductive Toxicity(02/25/2011)

Cancer (07/01/1987)

Cancer (02/22/2013)
Actinomycin D

Developmental Toxicity(10/01/1992)

Aflatoxins

Cancer (01/01/1988)

Alachlor

Cancer (01/01/1989)

Alcoholic Beverages, when associated with alcohol abuse

Cancer (07/01/1988)

AldrinCancer (07/01/1988)

All-trans Retinoic Acid

Developmental Toxicity(01/01/1989)

Aloe Vera, non-decolorized whole leaf extract

Cancer (12/04/2015)

Cancer (11/02/2012)
α-Methyl styrene (alpha-Methylstyrene)

Alprazolam

Female Reproductive Toxicity(07/29/2011)

Developmental Toxicity(07/01/1990)
Developmental Toxicity(08/20/1999)

Altretamine

Amantadine Hydrochloride

Male Reproductive Toxicity(08/20/1999)

Developmental Toxicity(02/27/2001)

Amikacin Sulfate

Developmental Toxicity(07/01/1990)

1-Amino-2,4-dibromoanthraquinone

Cancer (08/26/1997)

1-Amino-2-methylanthraquinone

Cancer (10/01/1989)

4-Amino-2-nitrophenol

Cancer (01/29/1999)
Developmental Toxicity(07/15/2016)

Des-ethyl atrazine (DEA)

Female Reproductive Toxicity(07/15/2016)

3-Amino-9-ethylcarbazole hydrochloride

Cancer (07/01/1989)

A-alpha-C (2-Amino-9H-pyrido[2,3-b]indole)

Cancer (01/01/1990)

2-Aminoanthraquinone

Cancer (10/01/1989)

p-Aminoazobenzene

Cancer (01/01/1990)

o-Aminoazotoluene

Cancer (07/01/1987)

4-Aminobiphenyl (4-aminodiphenyl)

Cancer (02/27/1987)

2-Aminofluorene

Cancer (01/29/1999)

Aminoglutethimide

Developmental Toxicity(07/01/1990)

Aminoglycosides

Developmental Toxicity(10/01/1992)
Developmental Toxicity(07/01/1987)

Aminopterin

Female Reproductive Toxicity(07/01/1987)
Developmental Toxicity(08/26/1997)

Amiodarone Hydrochloride

Female Reproductive Toxicity(08/26/1997)
Male Reproductive Toxicity(08/26/1997)

AmitrazDevelopmental Toxicity(03/30/1999)

Amitrole

Cancer (07/01/1987)

Amoxapine

Developmental Toxicity(05/15/1998)

Amsacrine

Cancer (08/07/2009)
Female Reproductive Toxicity(04/01/1990)

Anabolic Steroids

Male Reproductive Toxicity(04/01/1990)

Analgesic mixtures containing Phenacetin

Cancer (02/27/1987)

Androstenedione

Cancer (05/03/2011)

Angiotensin converting enzyme (ACE) inhibitors

Developmental Toxicity(10/01/1992)

Aniline

Cancer (01/01/1990)

Aniline Hydrochloride

Cancer (05/15/1998)

o-Anisidine

Cancer (07/01/1987)

o-Anisidine Hydrochloride

Cancer (07/01/1987)

Anisindione

Developmental Toxicity(10/01/1992)

Anthraquinone

Cancer (09/28/2007)

Antimony Oxide (Antimony trioxide)

Cancer (10/01/1990)

AramiteCancer (07/01/1987)

Areca Nut

Cancer (02/03/2006)

Aristolochic Acids

Cancer (07/09/2004)

Arsenic (inorganic oxides)

Developmental Toxicity(05/01/1997)

Arsenic (inorganic arsenic compounds)

Cancer (02/27/1987)

Asbestos

Cancer (02/27/1987)

Aspirin (NOTE: It is especially important not to use aspirinduring the last three months of pregnancy, unlessspecifically directed to do so by a physician because it
may cause problems in the unborn child or complications
during delivery.)

Developmental Toxicity(07/01/1990)

Female Reproductive Toxicity(07/01/1990)

Atenolol

Developmental Toxicity(08/26/1997)
Developmental Toxicity(07/15/2016)

Atrazine

Female Reproductive Toxicity(07/15/2016)
Developmental Toxicity(07/15/2016)

Des-isopropyl atrazine (DIA)

Female Reproductive Toxicity(07/15/2016)

Auramine

Cancer (07/01/1987)

Auranofin

Developmental Toxicity(01/29/1999)

Avermectin B1 (Abamectin)

Developmental Toxicity(12/03/2010)

Azacitidine

Cancer (01/01/1992)

Azaserine

Cancer (07/01/1987)

Cancer (02/27/1987)
Azathioprine

Developmental Toxicity(09/01/1996)

Azobenzene

Cancer (01/01/1990)

Barbiturates

Developmental Toxicity(10/01/1992)

Beclomethasone Dipropionate

Developmental Toxicity(05/15/1998)
Developmental Toxicity(07/01/1991)

BenomylMale Reproductive Toxicity(07/01/1991)

Benthiavalicarb-isopropyl

Cancer (07/01/2008)

Benz(a)anthracene

Cancer (07/01/1987)
Cancer (02/27/1987)

BenzeneDevelopmental Toxicity(12/26/1997)
Male Reproductive Toxicity(12/26/1997)

Benzidine (and its salts)

Cancer (02/27/1987)

Benzidine-based Dyes

Cancer (10/01/1992)

Benzodiazepines

Developmental Toxicity(10/01/1992)

Benzofuran

Cancer (10/01/1990)

Benzophenone

Cancer (06/22/2012)

Benzotrichloride

Cancer (07/01/1987)

Benzo[a]pyrene

Cancer (07/01/1987)

Benzo[b]fluoranthene

Cancer (07/01/1987)

Benzo[j]fluoranthene

Cancer (07/01/1987)

Benzo[k]fluoranthene

Cancer (07/01/1987)

Benzphetamine Hydrochloride

Developmental Toxicity(04/01/1990)

Benzyl Chloride

Cancer (01/01/1990)

Benzyl Violet 4B

Cancer (07/01/1987)

Beryllium and beryllium compounds

Cancer (10/01/1987)

Betel quid with tobacco

Cancer (01/01/1990)

Betel quid without tobacco

Cancer (02/03/2006)

Bis(2-chloro-1-methylethyl)ether, Technical Grade

Cancer (10/29/1999)

Bis(2-chloroethyl) Ether

Cancer (04/01/1988)

Bis(chloromethyl) Ether

Cancer (02/27/1987)

2,2-Bis(bromomethyl)-1,3-propanediol

Cancer (05/01/1996)

Cancer (07/01/1987)

Bischloroethyl Nitrosourea (BCNU) (Carmustine)

Developmental Toxicity(07/01/1990)
Developmental Toxicity(04/11/2013)

Bisphenol A (BPA)

Female Reproductive Toxicity(05/11/2015)

Bitumens, extracts of steam-refined and air refinedCancer (01/01/1990)

Bracken Fern

Cancer (01/01/1990)
Developmental Toxicity(05/18/1999)

Bromacil Lithium Salt

Male Reproductive Toxicity(01/17/2003)

BromateCancer (05/31/2002)

Bromochloroacetic Acid

Cancer (04/06/2010)

Bromodichloroacetic acid

Cancer (07/29/2016)

Bromodichloromethane

Cancer (01/01/1990)

Bromoethane

Cancer (12/22/2000)

Bromoform

Cancer (04/01/1991)
Cancer (08/05/2016)
Developmental Toxicity(12/07/2004)

1-Bromopropane (1-BP)

Female Reproductive Toxicity(12/07/2004)
Male Reproductive Toxicity(12/07/2004)
Female Reproductive Toxicity(05/31/2005)

2-Bromopropane (2-BP)

2-Bromopropane (2-BP)

Male Reproductive Toxicity(05/31/2005)

Bromoxynil

Developmental Toxicity(10/01/1990)

Bromoxynil Octanoate

Developmental Toxicity(05/18/1999)

Butabarbital Sodium

Developmental Toxicity(10/01/1992)
Cancer (04/01/1988)
Developmental Toxicity(04/16/2004)
Female Reproductive Toxicity(04/16/2004)

1,3-Butadiene

Male Reproductive Toxicity(04/16/2004)

Cancer (02/27/1987)
1,4-Butanediol dimethanesulfonate (Busulfan)

Developmental Toxicity(01/01/1989)

Butyl Benzyl Phthalate

Developmental Toxicity(12/02/2005)

Butylated Hydroxyanisole

Cancer (01/01/1990)
Developmental Toxicity(06/18/1999)

2,4-D Butyric Acid

Male Reproductive Toxicity(06/18/1999)

beta-Butyrolactone

Cancer (07/01/1987)

C.I. Acid Red 114

Cancer (07/01/1992)

C.I. Basic Red 9 Monohydrochloride

Cancer (07/01/1989)

C.I. Direct Blue 15

Cancer (08/26/1997)

C.I. Direct Blue 218

Cancer (08/26/1997)

C.I. Disperse Yellow 3

Cancer (02/08/2013)

C.I. Solvent Yellow 14

Cancer (05/15/1998)

Cacodylic Acid

Cancer (05/01/1996)
Cancer (10/01/1987)

Cadmium

Developmental Toxicity(05/01/1997)
Male Reproductive Toxicity(05/01/1997)

Caffeic Acid

Cancer (10/01/1994)

CaptafolCancer (10/01/1988)

CaptanCancer (01/01/1990)

Carbamazepine

Developmental Toxicity(01/29/1999)
Cancer (02/05/2010)
Developmental Toxicity(08/07/2009)

Carbaryl

Female Reproductive Toxicity(08/07/2009)Male Reproductive Toxicity(08/07/2009)
Carbazole

Cancer (05/01/1996)

Carbon black (airborne, unbound particles of respirable
size)

Cancer (02/21/2003)

Developmental Toxicity(07/01/1989)
Carbon Disulfide

Female Reproductive Toxicity(07/01/1989)
Male Reproductive Toxicity(07/01/1989)

Carbon Monoxide

Developmental Toxicity(07/01/1989)

Carbon Tetrachloride

Cancer (10/01/1987)

Carbon-Black Extracts

Cancer (01/01/1990)

Carboplatin

Developmental Toxicity(07/01/1990)

N-Carboxymethyl-N-Nitrosourea

Cancer (01/25/2002)

CatecholCancer (07/15/2003)

Ceramic fibers (airborne particles of respirable size)

Cancer (07/01/1990)

Certain combined chemotherapy for lymphomas

Cancer (02/27/1987)

Chenodiol

Developmental Toxicity(04/01/1990)

ChloralCancer (09/13/2013)

Chloral Hydrate

Cancer (09/13/2013)
Cancer (02/27/1987)

Chlorambucil

Developmental Toxicity(01/01/1989)

Chloramphenicol Sodium Succinate

Cancer (09/27/2013)

Chlorcyclizine Hydrochloride

Developmental Toxicity(07/01/1987)

Chlordane

Cancer (07/01/1988)
Cancer (01/01/1988)

Chlordecone (Kepone)

Developmental Toxicity(01/01/1989)

Chlordiazepoxide

Developmental Toxicity(01/01/1992)

Chlordiazepoxide Hydrochloride

Developmental Toxicity(01/01/1992)

Chlordimeform

Cancer (01/01/1989)

Chlorendic Acid

Cancer (07/01/1989)

Chlorinated Paraffins (Avg. chain length C12; approx. 60
percent chlorine by weight)

Cancer (07/01/1989)

N,N-Bis(2-chloroethyl)-2-naphthylamine (Chlornapazine)

Cancer (02/27/1987)

3-Chloro-2-methylpropene

Cancer (07/01/1989)
Developmental Toxicity(07/15/2016)

2,4‑diamino‑6‑chloro-s-triazine (DACT)

Female Reproductive Toxicity(07/15/2016)

1-Chloro-4-nitrobenzene

Cancer (10/29/1999)

p-Chloro-o-toluidine

Cancer (01/01/1990)

5-Chloro-o-toluidine and its strong acid salts

Cancer (10/24/1997)

p-Chloro-o-toluidine, strong acid salts ofCancer (05/15/1998)

4-Chloro-o-phenylenediamine

Cancer (01/01/1988)

p-Chloroaniline

Cancer (10/01/1994)

p-Chloroaniline Hydrochloride

Cancer (05/15/1998)

Chloroethane (Ethyl Chloride)

Cancer (07/01/1990)

1-(2-Chloroethyl)-3-(4-methylcyclohexyl)-1-nitrosourea(Methyl-CCNU)

Cancer (10/01/1988)

Cancer (01/01/1988)
1-(2-Chloroethyl)-3-cyclohexyl-1-nitrosourea (CCNU)(Lomustine)

Developmental Toxicity(07/01/1990)
Cancer (10/01/1987)

Chloroform

Developmental Toxicity(08/07/2009)

Chloromethyl Methyl Ether (Technical Grade)

Cancer (02/27/1987)

Chloroprene

Cancer (06/02/2000)

2-Chloropropionic Acid

Male Reproductive Toxicity(08/07/2009)

Chlorothalonil

Cancer (01/01/1989)

Chlorotrianisene

Cancer (09/01/1996)

Chlorozotocin

Cancer (01/01/1992)

Chlorpyrifos

Developmental Toxicity(12/15/2017)
Cancer (02/27/1987)

Developmental Toxicity(12/19/2008)
Chromium (hexavalent compounds)

Female Reproductive Toxicity(12/19/2008)
Male Reproductive Toxicity(12/19/2008)

Chrysene

Cancer (01/01/1990)

Ciclosporin (Cyclosporin A; Cyclosporine)

Cancer (01/01/1992)

Cancer (01/29/1999)
Developmental Toxicity(01/29/1999)
Cidofovir

Female Reproductive Toxicity(01/29/1999)
Male Reproductive Toxicity(01/29/1999)

Cinnamyl Anthranilate

Cancer (07/01/1989)

Cisplatin

Cancer (10/01/1988)

Citrus Red No. 2

Cancer (10/01/1989)

Cladribine

Developmental Toxicity(09/01/1996)

Clarithromycin

Developmental Toxicity(05/01/1997)
Developmental Toxicity(05/15/1998)

Clobetasol Propionate

Female Reproductive Toxicity(05/15/1998)

Clofibrate

Cancer (09/01/1996)
Cancer (05/24/2013)

Clomiphene Citrate

Developmental Toxicity(04/01/1990)

Clorazepate Dipotassium

Developmental Toxicity(10/01/1992)

Cobalt (II) Oxide

Cancer (07/01/1992)

Cobalt Metal Powder

Cancer (07/01/1992)

Cobalt Sulfate

Cancer (05/20/2005)

Cobalt Sulfate Heptahydrate

Cancer (06/02/2000)
Developmental Toxicity(07/01/1989)

CocaineFemale Reproductive Toxicity(07/01/1989)

Coconut oil diethanolamine condensate (cocamide
diethanolamine)

Cancer (06/22/2012)

Codeine Phosphate

Developmental Toxicity(05/15/1998)

Coke Oven Emissions

Cancer (02/27/1987)
Developmental Toxicity(10/01/1992)

Colchicine

Male Reproductive Toxicity(10/01/1992)
Cancer (02/27/1987)

Conjugated Estrogens

Developmental Toxicity(04/01/1990)

Creosotes

Cancer (10/01/1988)

p-Cresidine

Cancer (01/01/1988)

CumeneCancer (04/06/2010)

Cupferron

Cancer (01/01/1988)

Cyanazine

Developmental Toxicity(04/01/1990)

Hydrogen cyanide (HCN) and cyanide salts (CN salts)

Male Reproductive Toxicity(07/05/2013)

CycasinCancer (01/01/1988)

Cycloate

Developmental Toxicity(03/19/1999)

Cycloheximide

Developmental Toxicity(01/01/1989)

Cyclopenta[cd]pyrene

Cancer (04/29/2011)
Cancer (02/27/1987)
Developmental Toxicity(01/01/1989)

Cyclophosphamide (Anhydrous)

Female Reproductive Toxicity(01/01/1989)
Male Reproductive Toxicity(01/01/1989)
Cancer (02/27/1987)

Developmental Toxicity(01/01/1989)
Cyclophosphamide (Hydrated)

Female Reproductive Toxicity(01/01/1989)
Male Reproductive Toxicity(01/01/1989)

Cyhexatin

Developmental Toxicity(01/01/1989)

Cytarabine

Developmental Toxicity(01/01/1989)

Cytembena

Cancer (05/15/1998)

D&C Orange No. 17

Cancer (07/01/1990)

D&C Red No. 19

Cancer (07/01/1990)

D&C Red No. 8

Cancer (10/01/1990)

D&C Red No. 9

Cancer (07/01/1990)
Cancer (01/01/1988)

Dacarbazine

Developmental Toxicity(01/29/1999)

Daminozide

Cancer (01/01/1990)

Danazol

Developmental Toxicity(04/01/1990)

Dantron (Chrysazin; 1,8-Dihydroxyanthraquinone)

Cancer (01/01/1992)

Daunomycin

Cancer (01/01/1988)

Daunorubicin Hydrochloride

Developmental Toxicity(07/01/1990)
Developmental Toxicity(05/15/1998)
Female Reproductive Toxicity(05/15/1998)

o,p'-DDT

Demeclocycline Hydrochloride (internal use)

Male Reproductive Toxicity(05/15/1998)

Developmental Toxicity(01/01/1992)
Cancer (01/01/1988)

Di(2-ethylhexyl)phthalate (DEHP)

Developmental Toxicity(10/24/2003)
Male Reproductive Toxicity(10/24/2003)

Di-isodecyl Phthalate (DIDP)

Developmental Toxicity(04/20/2007)
Developmental Toxicity(12/02/2005)

Di-n-butyl Phthalate (DBP)

Female Reproductive Toxicity(12/02/2005)
Male Reproductive Toxicity(12/02/2005)
Female Reproductive Toxicity(12/02/2005)

Di-n-hexyl Phthalate (DnHP)

Male Reproductive Toxicity(12/02/2005)

Di-n-propyl Isocinchomeronate (MGK Repellent 326)

Cancer (05/01/1996)

N,N'-Diacetylbenzidine

Cancer (10/01/1989)

2,4-Diaminoanisole

Cancer (10/01/1990)

2,4-Diaminoanisole Sulfate

Cancer (01/01/1988)

4,4'-Diaminodiphenyl ether (4,4'-Oxydianiline)

Cancer (01/01/1988)

2,4-Diaminotoluene

Cancer (01/01/1988)

3,3'-Dimethoxybenzidine (o-Dianisidine)

Cancer (01/01/1988)

Diazepam

Developmental Toxicity(01/01/1992)

Diazoaminobenzene

Cancer (05/20/2005)

Diazoxide

Developmental Toxicity(02/27/2001)

Dibenzanthracenes

Cancer (12/26/2014)

Dibenzo[a,e]pyrene

Cancer (01/01/1988)

Dibenzo[a,h]pyrene

Cancer (01/01/1988)

Dibenzo[a,i]pyrene

Cancer (01/01/1988)Dibenzo[a,l]pyrene

Cancer (01/01/1988)

7H-dibenzo[c,g]carbazole

Cancer (01/01/1988)

Dibenz[a,c]anthracene

Cancer (12/26/2014)

Dibenz[a,h]acridine

Cancer (01/01/1988)

Dibenz[a,h]anthracene

Cancer (01/01/1988)

Dibenz[a,j]acridine

Cancer (01/01/1988)

Dibenz[a,j]anthracene

Cancer (12/26/2014)

2,3-Dibromo-1-propanol

Cancer (10/01/1994)
Cancer (07/01/1987)

1,2-Dibromo-3-chloropropane (DBCP)

Male Reproductive Toxicity(02/27/1987)

Dibromoacetic Acid

Cancer (06/17/2008)

Dibromoacetonitrile

Cancer (05/03/2011)
Cancer (07/01/1987)
Developmental Toxicity(05/15/1998)

Ethylene dibromide

Male Reproductive Toxicity(05/15/1998)

1,4-Dichloro-2-butene

Cancer (01/01/1990)

1,3-Dichloro-2-propanol (1,3-DCP)

Cancer (10/08/2010)

3,3'-Dichloro-4,4'-diamino-diphenyl Ether

Cancer (01/01/1988)

Cancer (05/01/1996)

Dichloroacetic Acid

Developmental Toxicity(08/07/2009)
Male Reproductive Toxicity(08/07/2009)

p-Dichlorobenzene

Cancer (01/01/1989)

3,3'-Dichlorobenzidine

Cancer (10/01/1987)

3,3'-Dichlorobenzidine Dihydrochloride

Cancer (05/15/1998)

DDD (Dichlorodiphenyldichloroethane)

Cancer (01/01/1989)
Cancer (01/01/1989)

DDE (Dichlorodiphenyldichloroethylene)

Developmental Toxicity(03/30/2010)
Male Reproductive Toxicity(03/30/2010)
Cancer (10/01/1987)
Developmental Toxicity(05/15/1998)
Female Reproductive Toxicity(05/15/1998)

DDT (Dichlorodiphenyltrichloroethane)

Male Reproductive Toxicity(05/15/1998)

1,1-Dichloroethane

Cancer (01/01/1990)

Ethylene dichloride (1,2-Dichloroethane)

Cancer (10/01/1987)

Vinylidene Chloride (1,1-Dichloroethylene)

Cancer (12/29/2017)

Dichlorophene

Developmental Toxicity(04/27/1999)

1,2-Dichloropropane

Cancer (01/01/1990)

1,3-Dichloropropene

Cancer (01/01/1989)

Dichlorphenamide

Developmental Toxicity(02/27/2001)

DDVP (Dichlorvos)

Cancer (01/01/1989)
Cancer (04/06/2010)

Diclofop-Methyl

Developmental Toxicity(03/05/1999)

Dicumarol

Developmental Toxicity(10/01/1992)

Dieldrin

Cancer (07/01/1988)

Diepoxybutane

Cancer (01/01/1988)

Diesel Engine Exhaust

Cancer (10/01/1990)

Diethanolamine

Cancer (06/22/2012)

Diethyl Sulfate

Cancer (01/01/1988)

1,2-Diethylhydrazine

Cancer (01/01/1988)
Cancer (02/27/1987)

Diethylstilbestrol (DES)

Developmental Toxicity(07/01/1987)
Developmental Toxicity(01/29/1999)

Diflunisal

Female Reproductive Toxicity(01/29/1999)

Diglycidyl Resorcinol Ether (DGRE)

Cancer (07/01/1989)

Dihydroergotamine Mesylate

Developmental Toxicity(05/01/1997)

Dihydrosafrole

Cancer (01/01/1988)

Diisononyl Phthalate (DINP)

Cancer (12/20/2013)

Diisopropyl Sulfate

Cancer (04/01/1993)

Diltiazem Hydrochloride

Developmental Toxicity(02/27/2001)

3,3'-Dimethylbenzidine dihydrochloride

Cancer (04/01/1992)

3,3'-Dimethoxybenzidine dihydrochloride

Cancer (10/01/1990)

3,3'-Dimethoxybenzidine-based dyes metabolized to 3,3'dimethoxybenzidine

Cancer (06/11/2004)

Dimethyl Sulfate

Cancer (01/01/1988)

2,6-Dimethyl-N-nitrosomorpholine (DMNM)

Cancer (02/08/2013)

N,N-Dimethyl-p-toluidine

Cancer (05/02/2014)
Developmental Toxicity(05/21/2010)

N,N-Dimethylacetamide

Male Reproductive Toxicity(12/20/2013)

4-Dimethylaminoazobenzene

Cancer (01/01/1988)

7,12-Dimethylbenz(a)anthracene

Cancer (01/01/1990)

3,3'-Dimethylbenzidine (ortho-Tolidine)

Cancer (01/01/1988)

3,3'-Dimethylbenzidine-based dyes metabolized to 3,3'dimethylbenzidine

Cancer (06/11/2004)

Dimethylcarbamoyl Chloride

Cancer (01/01/1988)

N,N-Dimethylformamide

Cancer (10/27/2017)

1,2-Dimethylhydrazine

Cancer (01/01/1988)

1,1-Dimethylhydrazine (UDMH)

Cancer (10/01/1989)

Dimethylvinylchloride

Cancer (07/01/1989)

p-Dinitrobenzene

Male Reproductive Toxicity(07/01/1990)

m-Dinitrobenzene

Male Reproductive Toxicity(07/01/1990)

o-Dinitrobenzene

Male Reproductive Toxicity(07/01/1990)

3,7-Dinitrofluoranthene

Cancer (08/26/1997)

3,9-Dinitrofluoranthene

Cancer (08/26/1997)

1,6-Dinitropyrene

Cancer (10/01/1990)

1,8-Dinitropyrene

Cancer (10/01/1990)

1,3-Dinitropyrene

Cancer (11/02/2012)
Cancer (07/01/1995)

2,6-Dinitrotoluene

Male Reproductive Toxicity(08/20/1999)

Cancer (07/01/1988)
2,4-Dinitrotoluene

Male Reproductive Toxicity(08/20/1999)
Female Reproductive Toxicity(08/20/1999)

Dinitrotoluene (Technical Grade)

Dinitrotoluene Mixture, 2,4-/2,6-

Male Reproductive Toxicity(08/20/1999)

Cancer (05/01/1996)

Dinocap

Developmental Toxicity(04/01/1990)

Dinoseb

Male Reproductive Toxicity(01/01/1989)

1,4-Dioxane

Cancer (01/01/1988)
Cancer (01/01/1988)

Diphenylhydantoin (Phenytoin)

Developmental Toxicity(07/01/1987)

Diphenylhydantoin (Phenytoin), Sodium Salt

Cancer (01/01/1988)

Direct Black 38 (Technical Grade)

Cancer (01/01/1988)

Direct Blue 6 (Technical Grade)

Cancer (01/01/1988)

Direct Brown 95 (Technical Grade)

Cancer (10/01/1988)

Disodium Cyanodithioimidocarbonate

Developmental Toxicity(03/30/1999)

Disperse Blue 1

Cancer (10/01/1990)

DiuronCancer (05/31/2002)
Cancer (07/01/1987)

Doxorubicin Hydrochloride (Adriamycin)

Developmental Toxicity(01/29/1999)
Male Reproductive Toxicity(01/29/1999)

Doxycycline (internal use)

Developmental Toxicity(07/01/1990)

Doxycycline Calcium (internal use)

Developmental Toxicity(01/01/1992)

Doxycycline Hyclate (internal use)

Developmental Toxicity(10/01/1991)

Doxycycline Monohydrate (internal use)

Developmental Toxicity(10/01/1991)

Emissions from combustion of coal

Cancer (08/07/2013)

Emissions from high-temperature unrefined rapeseed oil

Cancer (01/03/2014)

EndrinDevelopmental Toxicity(05/15/1998)

Environmental Tobacco Smoke (ETS)

Developmental Toxicity(06/09/2006)
Cancer (10/01/1987)

Epichlorohydrin

Male Reproductive Toxicity(09/01/1996)

Epoxiconazole

Cancer (04/15/2011)

Ergotamine Tartrate

Developmental Toxicity(04/01/1990)

Erionite

Cancer (10/01/1988)

Estradiol 17B

Cancer (01/01/1988)

Estragole

Cancer (10/29/1999)

Estrogen-Progestogen (Combined) used as menopausal
therapy

Cancer (11/04/2011)

Estrogens, Steroidal

Cancer (08/19/2005)

EstroneCancer (01/01/1988)
Cancer (08/26/1997)

Estropipate

Developmental Toxicity(08/26/1997)

Ethanol in alcoholic beverages

Cancer (04/29/2011)

Ethinylestradiol

Cancer (01/01/1988)

Ethionamide

Developmental Toxicity(08/26/1997)

Ethoprop

Cancer (02/27/2001)

Ethyl Acrylate

Cancer (07/01/1989)

Ethyl alcohol in alcoholic beverages

Developmental Toxicity(10/01/1987)

Ethyl Dipropylthiocarbamate

Developmental Toxicity(04/27/1999)

Ethyl Methanesulfonate

Cancer (01/01/1988)

Ethyl-4-4'-dichlorobenzilate

Cancer (01/01/1990)

Ethylbenzene

Cancer (06/11/2004)

Ethylene glycol (ingested)

Developmental Toxicity(06/19/2015)
Developmental Toxicity(01/01/1989)

Ethylene Glycol Monoethyl Ether

Male Reproductive Toxicity(01/01/1989)
Developmental Toxicity(01/01/1993)

Ethylene Glycol Monoethyl Ether Acetate

Male Reproductive Toxicity(01/01/1993)
Developmental Toxicity(01/01/1989)

Ethylene Glycol Monomethyl Ether

Male Reproductive Toxicity(01/01/1989)
Developmental Toxicity(01/01/1993)

Ethylene Glycol Monomethyl Ether Acetate

Male Reproductive Toxicity(01/01/1993)
Cancer (07/01/1987)
Developmental Toxicity(08/07/2009)

Ethylene Oxide

Female Reproductive Toxicity(02/27/1987)
Male Reproductive Toxicity(08/07/2009)
Cancer (01/01/1988)

Ethylene Thiourea

Developmental Toxicity(01/01/1993)

Ethyleneimine

Cancer (01/01/1988)
Developmental Toxicity(08/20/1999)

EtodolacFemale Reproductive Toxicity(08/20/1999)
Cancer (11/04/2011)

Etoposide

Developmental Toxicity(07/01/1990)

Etoposide in combination with cisplatin and bleomycin

Cancer (11/04/2011)

Etretinate

Developmental Toxicity(07/01/1987)

Fenoxaprop Ethyl

Developmental Toxicity(03/26/1999)

Fenoxycarb

Cancer (06/02/2000)

Filgrastim

Developmental Toxicity(02/27/2001)

Fluazifop Butyl

Developmental Toxicity(11/06/1998)
Developmental Toxicity(05/15/1998)

Flunisolide

Fluorouracil

Female Reproductive Toxicity(05/15/1998)

Developmental Toxicity(01/01/1989)

Fluoxymesterone

Developmental Toxicity(04/01/1990)

Flurazepam Hydrochloride

Developmental Toxicity(10/01/1992)
Developmental Toxicity(08/20/1999)

Flurbiprofen

Female Reproductive Toxicity(08/20/1999)

Flutamide

Developmental Toxicity(07/01/1990)

Fluticasone Propionate

Developmental Toxicity(05/15/1998)

Fluvalinate

Developmental Toxicity(11/06/1998)

FolpetCancer (01/01/1989)

Formaldehyde (gas)Cancer (01/01/1988)

Fumonisin B1Cancer (11/14/2003)

5-(Morpholinomethyl)-3-[(5-nitrofurfurylidene)-amino]-2oxazolidinone

Cancer (04/01/1988)

Furan

Cancer (10/01/1993)

N-[4-(5-Nitro-2-furyl)-2-thiazolyl]acetamide

Cancer (04/01/1988)

Furazolidone

Cancer (01/01/1990)

Furfuryl Alcohol

Cancer (09/30/2016)

2-Amino-5-(5-nitro-2-furyl)-1,3,4-thiadiazole

Cancer (07/01/1987)

Furmecyclox

Cancer (01/01/1990)

AF-2;[2-(2-furyl)-3-(5-nitro-2-furyl)]acrylamide

Cancer (07/01/1987)

Fusarin C

Cancer (07/01/1995)

Gallium Arsenide

Cancer (08/01/2008)
Cancer (08/26/1997)

Ganciclovir

Developmental Toxicity(08/26/1997)
Male Reproductive Toxicity(08/26/1997)
Developmental Toxicity(08/26/1997)

Ganciclovir Sodium

Gasoline engine exhaust (condensates/extracts)

Male Reproductive Toxicity(08/26/1997)

Cancer (10/01/1990)

Cancer (12/22/2000)

Gemfibrozil

Female Reproductive Toxicity(08/20/1999)
Male Reproductive Toxicity(08/20/1999)

Glass wool fibers (inhalable and biopersistent)

Cancer (07/01/1990)

Glu-P-1 (2-Amino-6-methyldipyrido[1-2-a:3'-2'd]imidazole)

Cancer (01/01/1990)

Glu-P-2 (2-Aminodipyrido[1,2-a:3',2'-d]imidazole)

Cancer (01/01/1990)

Glycidaldehyde

Cancer (01/01/1988)

GlycidolCancer (07/01/1990)

Glyphosate

Cancer (07/07/2017)

Goldenseal root powder

Cancer (12/04/2015)
Developmental Toxicity(08/26/1997)

Goserelin Acetate

Female Reproductive Toxicity(08/26/1997)
Male Reproductive Toxicity(08/26/1997)

GriseofulvinCancer (01/01/1990)

Gyromitrin

Cancer (01/01/1988)

Halazepam

Developmental Toxicity(07/01/1990)

Halobetasol Propionate

Developmental Toxicity(08/20/1999)

Developmental Toxicity(01/29/1999)
Haloperidol

Female Reproductive Toxicity(01/29/1999)

Halothane

Developmental Toxicity(09/01/1996)

HC Blue 1

Cancer (07/01/1989)
Cancer (07/01/1988)

Heptachlor

Developmental Toxicity(08/20/1999)

Heptachlor Epoxide

Cancer (07/01/1988)

Herbal remedies containing plant species of the genus
Aristolochia

Cancer (07/09/2004)

Cancer (10/01/1987)
Hexachlorobenzene

Developmental Toxicity(01/01/1989)

Hexachlorobutadiene

Cancer (05/03/2011)

Hexachlorocyclohexane (Technical Grade)

Cancer (10/01/1987)

Hexachlorodibenzodioxin

Cancer (04/01/1988)

Hexachloroethane

Cancer (07/01/1990)

2,4-Hexadienal (89% trans, trans isomer; 11% cis, transisomer)Cancer (03/04/2005)

Developmental Toxicity(06/06/2014)
Hexafluoroacetone

Male Reproductive Toxicity(08/01/2008)
Cancer (01/01/1988)

Hexamethylphosphoramide

Male Reproductive Toxicity(10/01/1994)

n-Hexane

Male Reproductive Toxicity(12/15/2017)

2,5-Hexanedione

Male Reproductive Toxicity(12/04/2015)

Histrelin Acetate

Developmental Toxicity(05/15/1998)
Developmental Toxicity(03/05/1999)

Hydramethylnon

Male Reproductive Toxicity(03/05/1999)

Hydrazine

Cancer (01/01/1988)

Hydrazine sulfate

Cancer (01/01/1988)

Hydrazobenzene (1,2-Diphenylhydrazine)

Cancer (01/01/1988)

1-Hydroxyanthraquinone

Cancer (05/27/2005)

Hydroxyurea

Developmental Toxicity(05/01/1997)
Developmental Toxicity(08/20/1999)

Idarubicin Hydrochloride

Male Reproductive Toxicity(08/20/1999)

Ifosfamide

Developmental Toxicity(07/01/1990)

Imazalil

Cancer (05/20/2011)

Indeno[1,2,3-cd]pyrene

Cancer (01/01/1988)

Indium Phosphide

Cancer (02/27/2001)

Iodine-131

Developmental Toxicity(01/01/1989)

Iprodione

Cancer (05/01/1996)

Iprovalicarb

Cancer (06/01/2007)

IQ (2-Amino-3-methylimidazo-[4-5-f]quinoline)

Cancer (04/01/1990)

Iron Dextran Complex

Cancer (01/01/1988)

Isobutyl Nitrite

Cancer (05/01/1996)

Isoprene

Cancer (05/01/1996)

Isopyrazam

Cancer (07/24/2012)

Isotretinoin

Developmental Toxicity(07/01/1987)

Isoxaflutole

Cancer (12/22/2000)

Kresoxim-methyl

Cancer (02/03/2012)

Lactofen

Cancer (01/01/1989)

Lasiocarpine

Cancer (04/01/1988)

Lead Acetate

Cancer (01/01/1988)
Cancer (10/01/1992)
Developmental Toxicity(02/27/1987)

Lead and Lead Compounds

Female Reproductive Toxicity(02/27/1987)
Male Reproductive Toxicity(02/27/1987)

Lead Phosphate

Cancer (04/01/1988)

Lead Subacetate

Cancer (10/01/1989)

Leather Dust

Cancer (04/29/2011)
Developmental Toxicity(08/26/1997)

Leuprolide Acetate

Female Reproductive Toxicity(08/26/1997)
Male Reproductive Toxicity(08/26/1997)

Levodopa

Developmental Toxicity(01/29/1999)

Levonorgestrel Implants

Female Reproductive Toxicity(05/15/1998)

Lindane and other hexachlorocyclohexane isomers

Cancer (10/01/1989)

LinuronDevelopmental Toxicity(03/19/1999)

Lithium Carbonate

Developmental Toxicity(01/01/1991)

Lithium Citrate

Developmental Toxicity(01/01/1991)

Lorazepam

Developmental Toxicity(07/01/1990)

Lovastatin

Developmental Toxicity(10/01/1992)

Lynestrenol

Cancer (02/27/2001)

Malathion

Cancer (05/20/2016)

Malonaldehyde, Sodium Salt

Cancer (05/03/2011)

Mancozeb

Cancer (01/01/1990)

Maneb

Cancer (01/01/1990)

Marijuana Smoke

Cancer (06/19/2009)

Me-A-alpha-C (2-Amino-3-methyl-9H-pyrido[2,3-b]indole)

Cancer (01/01/1990)

Mebendazole

Developmental Toxicity(08/20/1999)
Cancer (01/01/1988)

Nitrogen Mustard (Mechlorethamine)

Developmental Toxicity(01/01/1989)
Cancer (04/01/1988)

Nitrogen Mustard Hydrochloride (Mechlorethamine
Hydrochloride)

Developmental Toxicity(07/01/1990)
Cancer (01/01/1990)

Medroxyprogesterone Acetate

Developmental Toxicity(04/01/1990)
Cancer (03/28/2014)

Megestrol Acetate

Developmental Toxicity(01/01/1991)

MeIQ (2-Amino-3,4-dimethylimidazo[4,5-f]quinoline)

Cancer (10/01/1994)

MeIQx (2-Amino-3,8-dimethylimidazo[4,5-f]quinoxaline)

Cancer (10/01/1994)

Cancer (02/27/1987)
Melphalan

Menotropins

Developmental Toxicity(07/01/1990)

Developmental Toxicity(04/01/1990)

Mepanipyrim

Cancer (07/01/2008)

Meprobamate

Developmental Toxicity(01/01/1992)

2-Mercaptobenzothiazole

Cancer (10/27/2017)

Mercaptopurine

Developmental Toxicity(07/01/1990)

Mercury and Mercury Compounds

Developmental Toxicity(07/01/1990)

Merphalan

Cancer (04/01/1988)

Mestranol

Cancer (04/01/1988)

Metam Potassium

Cancer (12/31/2010)

Methacycline Hydrochloride

Developmental Toxicity(01/01/1991)
Cancer (11/06/1998)

Metham Sodium

Developmental Toxicity(05/15/1998)

MethanolDevelopmental Toxicity(03/16/2012)

Methazole

Developmental Toxicity(12/01/1999)

Methimazole

Developmental Toxicity(07/01/1990)

Methotrexate

Developmental Toxicity(01/01/1989)

Methotrexate Sodium

Developmental Toxicity(04/01/1990)

5-Methoxypsoralen with ultraviolet A therapy

Cancer (10/01/1988)

8-Methoxypsoralen with ultraviolet A therapy

Cancer (02/27/1987)

Methyl Bromide, as a structural fumigant

Developmental Toxicity(01/01/1993)

Methyl Carbamate

Cancer (05/15/1998)
Developmental Toxicity(03/10/2000)

Methyl Chloride

Methyl Iodide

Male Reproductive Toxicity(03/07/2014)
Cancer (04/01/1988)
Cancer (11/04/2011)

Methyl Isobutyl Ketone (MIBK)

Developmental Toxicity(03/28/2014)
Developmental Toxicity(11/12/2010)

Methyl Isocyanate (MIC)

Methyl Methanesulfonate

Female Reproductive Toxicity(11/12/2010)
Cancer (04/01/1988)
Developmental Toxicity(12/04/2015)

Methyl-n-Butyl Ketone

Methyl-n-Butyl Ketone

Male Reproductive Toxicity(08/07/2009)

2-Methyl-1-nitroanthraquinone (of uncertain purity)

Cancer (04/01/1988)

N-Methyl-N'-nitro-N-nitrosoguanidine

Cancer (04/01/1988)

Methylazoxymethanol

Cancer (04/01/1988)

Methylazoxymethanol Acetate

Cancer (04/01/1988)

3-MethylcholanthreneCancer (01/01/1990)

5-Methylchrysene

Cancer (04/01/1988)

4,4'-Methylene bis(2-chloroaniline)

Cancer (07/01/1987)

4,4'-Methylene bis(2-methylaniline)

Cancer (04/01/1988)

Dichloromethane (Methylene Chloride)

Cancer (04/01/1988)

4,4'-Methylenedianiline

Cancer (01/01/1988)

4,4'-Methylenedianiline dihydrochloride

Cancer (01/01/1988)

Methyleugenol

Cancer (11/16/2001)

Methylhydrazine and its salts

Cancer (07/01/1992)

2-Methylimidazole

Cancer (06/22/2012)

4-Methylimidazole

Cancer (01/07/2011)
Cancer (05/01/1996)

Methylmercury and methylmercury compounds

Developmental Toxicity(07/01/1987)

n-Methylolacrylamide

Cancer (07/01/1990)

n-Methylpyrrolidone

Developmental Toxicity(06/15/2001)

Methyltestosterone

Developmental Toxicity(04/01/1990)

Methylthiouracil

Cancer (10/01/1989)
Cancer (01/01/1990)

MetiramDevelopmental Toxicity(03/30/1999)

Metronidazole

Cancer (01/01/1988)

Michler's Ketone

Cancer (01/01/1988)

Midazolam Hydrochloride

Developmental Toxicity(07/01/1990)

Minocycline Hydrochloride (internal use)

Developmental Toxicity(01/01/1992)

Mirex

Cancer (01/01/1988)

Misoprostol

Developmental Toxicity(04/01/1990)

Mitomycin C

Cancer (04/01/1988)

Cancer (01/23/2015)
Mitoxantrone Hydrochloride

Developmental Toxicity(07/01/1990)
Developmental Toxicity(12/11/2009)

Molinate

Female Reproductive Toxicity(12/11/2009)
Male Reproductive Toxicity(12/11/2009)

MON 13900 (Furilazole)

Cancer (03/22/2011)

MON 4660 (Dichloroacetyl-1-oxa-4-azaspiro(4,5)-decane)

Cancer (03/22/2011)

3-Monochloropropane-1,2-diol (3-MCPD)

Cancer (10/08/2010)

Monocrotaline

Cancer (04/01/1988)

MOPP (vincristine-prednisone-nitrogen mustardprocarbazine mixture)

Cancer (11/04/2011)

Mustard Gas

Cancer (02/27/1987)

MX (3-chloro-4-dichloromethyl-5-hydroxy-2(5H)-furanone)

Cancer (12/22/2000)

Developmental Toxicity(04/16/1999)
Myclobutanil

Myclobutanil

Male Reproductive Toxicity(04/16/1999)

beta-Myrcene

Cancer (03/24/2015)

Nabam

Developmental Toxicity(03/30/1999)

Nafarelin Acetate

Developmental Toxicity(04/01/1990)

Nafenopin

Cancer (04/01/1988)

Nalidixic Acid

Cancer (05/15/1998)

Naphthalene

Cancer (04/19/2002)

2-Naphthylamine

Cancer (02/27/1987)

1-Naphthylamine

Cancer (10/01/1989)

Neomycin Sulfate (internal use)

Developmental Toxicity(10/01/1992)

Netilmicin Sulfate

Developmental Toxicity(07/01/1990)

Nickel Acetate

Cancer (10/01/1989)

Nickel (Metallic)

Cancer (10/01/1989)

Nickel Carbonate

Cancer (10/01/1989)
Cancer (10/01/1987)

Nickel Carbonyl

Developmental Toxicity(09/01/1996)

Nickel compounds

Cancer (05/07/2004)

Nickel Hydroxide

Cancer (10/01/1989)

Nickel Oxide

Cancer (10/01/1989)

Nickel Refinery Dust from the Pyrometallurgical Process

Cancer (10/01/1987)

Nickel Subsulfide

Cancer (10/01/1987)

Nickelocene

Cancer (10/01/1989)

Nicotine

Developmental Toxicity(04/01/1990)
Developmental Toxicity(01/29/1999)

Nifedipine

Female Reproductive Toxicity(01/29/1999)
Male Reproductive Toxicity(01/29/1999)

1-[(5-Nitrofurfurylidene)-amino]-2-imidazolidinone

Cancer (04/01/1988)

2-(2-Formylhydrazino)-4-(5-nitro-2-furyl)thiazole

Cancer (01/01/1988)

Nimodipine

Developmental Toxicity(04/24/2001)

Niridazole

Cancer (04/01/1988)
Cancer (10/05/2005)

Nitrapyrin

Developmental Toxicity(03/30/1999)

Nitrilotriacetic Acid

Cancer (01/01/1988)

Nitrilotriacetic Acid, Trisodium Salt Monohydrate

Cancer (04/01/1989)

5-Nitroacenaphthene

Cancer (04/01/1988)

o-Nitroanisole

Cancer (10/01/1992)
Cancer (08/26/1997)

Nitrobenzene

Male Reproductive Toxicity(03/30/2010)

4-Nitrobiphenyl

Cancer (04/01/1988)

6-Nitrochrysene

Cancer (10/01/1990)

Nitrofen (Technical Grade)

Cancer (01/01/1988)

2-Nitrofluorene

Cancer (10/01/1990)

Nitrofurantoin

Male Reproductive Toxicity(04/01/1991)

Nitrofurazone

Cancer (01/01/1990)

Nitrogen Mustard N-oxide

Cancer (04/01/1988)

Nitrogen Mustard N-oxide Hydrochloride

Cancer (04/01/1988)

Nitromethane

Cancer (05/01/1997)

2-Nitropropane

Cancer (01/01/1988)

1-Nitropyrene

Cancer (10/01/1990)

4-Nitropyrene

Cancer (10/01/1990)

N-Nitroso-N-ethylurea

Cancer (10/01/1987)

N-Nitrosomethylethylamine

Cancer (10/01/1989)

N-Nitroso-N-methylurea

Cancer (10/01/1987)

N-Nitroso-N-methylurethane

Cancer (04/01/1988)

N-Nitrosodi-n-Butylamine

Cancer (10/01/1987)

N-Nitrosodi-n-propylamine

Cancer (01/01/1988)

n-Nitrosodiethanolamine

Cancer (01/01/1988)

n-Nitrosodiethylamine

Cancer (10/01/1987)

n-Nitrosodimethylamine

Cancer (10/01/1987)

N-Nitrosodiphenylamine

Cancer (04/01/1988)

p-Nitrosodiphenylamine

Cancer (01/01/1988)

N-Nitrosomethyl-n-butylamine

Cancer (12/26/2014)

N-Nitrosomethyl-n-decylamine

Cancer (12/26/2014)

N-Nitrosomethyl-n-dodecylamine

Cancer (12/26/2014)

N-Nitrosomethyl-n-heptylamine

Cancer (12/26/2014)

N-Nitrosomethyl-n-hexylamine

Cancer (12/26/2014)

N-Nitrosomethyl-n-nonylamine

Cancer (12/26/2014)

N-Nitrosomethyl-n-octylamine

Cancer (12/26/2014)

N-Nitrosomethyl-n-pentylamine

Cancer (12/26/2014)

N-Nitrosomethyl-n-propylamine

Cancer (12/26/2014)

N-Nitrosomethyl-n-tetradecylamine

Cancer (12/26/2014)

N-Nitrosomethyl-n-undecylamine

Cancer (12/26/2014)

3-(N-Nitrosomethylamino) propionitrile

Cancer (04/01/1990)

4-(N-Nitrosomethylamino)-1-(3-pyridyl)1-butanone

Cancer (04/01/1990)

N-Nitrosomethylvinylamine

Cancer (01/01/1988)

n-Nitrosomorpholine

Cancer (01/01/1988)

N-Nitrosonornicotine

Cancer (01/01/1988)

N-Nitrosopiperidine

Cancer (01/01/1988)

N-Nitrosopyrrolidine

Cancer (10/01/1987)

N-Nitrososarcosine

Cancer (01/01/1988)

o-Nitrotoluene

Cancer (05/15/1998)
Developmental Toxicity(08/01/2008)

Nitrous Oxide

Female Reproductive Toxicity(08/01/2008)
Cancer (10/01/1989)

Norethisterone (Norethindrone)

Developmental Toxicity(04/01/1990)

Norethisterone (Norethindrone) /Ethinyl Estradiol

Developmental Toxicity(04/01/1990)

Norethisterone (Norethindrone) /Mestranol

Developmental Toxicity(04/01/1990)

Norethisterone Acetate (Norethindrone Acetate)

Developmental Toxicity(10/01/1991)

Norethynodrel

Cancer (02/27/2001)

Norgestrel

Developmental Toxicity(04/01/1990)

Ochratoxin A

Cancer (07/01/1990)

Oil Orange SS

Cancer (04/01/1988)

Oral Contraceptives, Combined

Cancer (10/01/1989)

Oral Contraceptives, Sequential

Cancer (10/01/1989)

Oryzalin

Cancer (09/12/2008)
Cancer (07/01/1991)

Oxadiazon

Developmental Toxicity(05/15/1998)
Cancer (10/01/1994)

Oxazepam

Developmental Toxicity(10/01/1992)
Female Reproductive Toxicity(11/06/1998)

Oxydemeton Methyl

Male Reproductive Toxicity(11/06/1998)
Cancer (01/01/1988)

Oxymetholone

Developmental Toxicity(05/01/1997)

Oxytetracycline (internal use)

Developmental Toxicity(01/01/1991)

Oxytetracycline hydrochloride (internal use)

Developmental Toxicity(10/01/1991)
Cancer (08/20/1999)

Oxythioquinox (Chinomethionat)

Developmental Toxicity(11/06/1998)
Developmental Toxicity(08/26/1997)

Paclitaxel

Female Reproductive Toxicity(08/26/1997)
Male Reproductive Toxicity(08/26/1997)

Palygorskite fibers (> 5mm in length)

Cancer (12/28/1999)

Panfuran S

Cancer (01/01/1988)

Paramethadione

Developmental Toxicity(07/01/1990)

Parathion

Cancer (05/20/2016)

Penicillamine

Developmental Toxicity(01/01/1991)

Pentabromodiphenyl ether mixture [DE-71 (technicalgrade)]

Cancer (07/07/2017)

Pentachlorophenol

Cancer (01/01/1990)

Pentachlorophenol and By-Products of its Synthesis(Complex Mixture)

Cancer (10/21/2016)

Pentobarbital Sodium

Developmental Toxicity(07/01/1990)

Pentosan Polysulfate Sodium

Cancer (04/18/2014)

Pentostatin

Developmental Toxicity(09/01/1996)

Perfluorooctane sulfonate (PFOS)

Developmental Toxicity(11/10/2017)

Perfluorooctanoic Acid (PFOA)

Developmental Toxicity(11/10/2017)

Pertuzumab

Developmental Toxicity(01/27/2017)

Phenacemide

Developmental Toxicity(07/01/1990)

Phenacetin

Cancer (10/01/1989)

Phenazopyridine

Cancer (01/01/1988)

Phenazopyridine Hydrochloride

Cancer (01/01/1988)

Phenesterin

Cancer (07/01/1989)

Phenobarbital

Cancer (01/01/1990)

Phenolphthalein

Cancer (05/15/1998)

Phenoxybenzamine

Cancer (04/01/1988)

Phenoxybenzamine Hydrochloride

Cancer (04/01/1988)

Phenprocoumon

Developmental Toxicity(10/01/1992)
Cancer (10/01/1990)

Phenyl Glycidyl Ether

Male Reproductive Toxicity(08/07/2009)o-Phenylenediamine and its salts

Cancer (05/15/1998)

Phenylhydrazine and its salts

Cancer (07/01/1992)

o-Phenylphenate, Sodium

Cancer (01/01/1990)

o-Phenylphenol

Cancer (08/04/2000)

Phenylphosphine

Male Reproductive Toxicity(08/07/2009)

PhiP(2-Amino-1-methyl-6-phenylimidazol[4,5-b]pyridine)

Cancer (10/01/1994)

Developmental Toxicity(08/20/1999)
Pimozide

Female Reproductive Toxicity(08/20/1999)

Pioglitazone

Cancer (04/18/2014)

Pipobroman

Developmental Toxicity(07/01/1990)

Pirimicarb

Cancer (07/01/2008)

Plicamycin

Developmental Toxicity(04/01/1990)

Polygeenan

Cancer (01/01/1988)
Cancer (01/01/1988)

Polybrominated biphenyls

Developmental Toxicity(10/01/1994)
Cancer (10/01/1989)

Polychlorinated Biphenyls

Developmental Toxicity(01/01/1991)

Polychlorinated biphenyls (containing 60 or more percent
chlorine by molecular weight)

Cancer (01/01/1988)

Polychlorinated dibenzo-p-dioxins

Cancer (10/01/1992)

Polychlorinated Dibenzofurans

Cancer (10/01/1992)

Ponceau 3R

Cancer (04/01/1988)

Ponceau MX

Cancer (04/01/1988)

Potassium bromate

Cancer (01/01/1990)

Potassium dimethyldithiocarbamate

Developmental Toxicity(03/30/1999)

Pravastatin sodium

Developmental Toxicity(03/03/2000)

Prednisolone sodium phosphate

Developmental Toxicity(08/20/1999)

Primidone

Cancer (08/20/1999)

Procarbazine

Cancer (01/01/1988)
Cancer (01/01/1988)

Procarbazine hydrochloride

Developmental Toxicity(07/01/1990)

Procymidone

Cancer (10/01/1994)

Progesterone

Cancer (01/01/1988)

Pronamide

Cancer (05/01/1996)

Propachlor

Cancer (02/27/2001)

1,3-Propane Sultone

Cancer (01/01/1988)
Cancer (10/01/1994)

Propargite

Developmental Toxicity(06/15/1999)
Developmental Toxicity(07/15/2016)

Propazine

Female Reproductive Toxicity(07/15/2016)

beta-Propiolactone

Cancer (01/01/1988)

Propoxur

Cancer (08/11/2006)

Propylene glycol mono-t-butyl ether

Cancer (06/11/2004)

Propylene Oxide

Cancer (10/01/1988)

2-Methylaziridine (Propyleneimine)

Cancer (01/01/1988)
Cancer (01/01/1988)

Propylthiouracil

Developmental Toxicity(07/01/1990)

Pulegone

Cancer (04/18/2014)

Pymetrozine

Cancer (03/22/2011)

CMNP (Pyrazachlor)

Cancer (08/25/2015)

Pyridine

Cancer (05/17/2002)

Pyrimethamine

Developmental Toxicity(01/29/1999)

Quazepam

Developmental Toxicity(08/26/1997)

Quinoline and its strong acid salts

Cancer (10/24/1997)

Quizalofop-ethyl

Male Reproductive Toxicity(12/24/1999)

Radionuclides

Cancer (07/01/1989)

Reserpine

Cancer (10/01/1989)

Residual (heavy) fuel oils

Cancer (10/01/1990)
Cancer (07/01/2008)

Resmethrin

Developmental Toxicity(11/06/1998)

Retinol/retinyl esters, when in daily dosages in excess of
10,000 IU or 3,000 retinol equivalents(NOTE:Retinol/retinyl esters are required and essential
for maintenance of normal reproductive function.
Recommended daily level during pregnancy is 8000 IU)

Developmental Toxicity(07/01/1989)

Developmental Toxicity(04/01/1990)
Ribavirin

Riddelliine

Male Reproductive Toxicity(02/27/2001)
Cancer (12/03/2004)
Developmental Toxicity(02/27/2001)

Rifampin

Female Reproductive Toxicity(02/27/2001)

SafroleCancer (01/01/1988)

Salted fish, Chinese-style

Cancer (04/29/2011)

Secobarbital Sodium

Developmental Toxicity(10/01/1992)

Sedaxane

Cancer (07/01/2016)

Selenium Sulfide

Cancer (10/01/1989)

Sermorelin Acetate

Developmental Toxicity(08/20/1999)

Shale-oils

Cancer (04/01/1990)

Silica, crystalline (airborne particles of respirable size)

Cancer (10/01/1988)

Developmental Toxicity(07/15/2016)
Simazine

Female Reproductive Toxicity(07/15/2016)

Sodium dimethyldithiocarbamate

Developmental Toxicity(03/30/1999)

Sodium Fluoroacetate

Male Reproductive Toxicity(11/06/1998)

Soots, tars, and mineral oils (untreated and mildly treatedoils and used engine oils)

Cancer (02/27/1987)

Spirodiclofen

Cancer (10/08/2010)

Spironolactone

Cancer (05/01/1997)

Stanozolol

Cancer (05/01/1997)

Sterigmatocystin

Cancer (04/01/1988)

Streptomycin Sulfate

Developmental Toxicity(01/01/1991)
Cancer (01/01/1988)
Developmental Toxicity(08/20/1999)

Streptozotocin (Streptozocin)

Female Reproductive Toxicity(08/20/1999)
Male Reproductive Toxicity(08/20/1999)

Strong inorganic acid mists containing sulfuric acid

Cancer (03/14/2003)

StyreneCancer (04/22/2016)

Styrene Oxide

Cancer (10/01/1988)

Sulfallate

Cancer (01/01/1988)
Cancer (05/15/1998)

Sulfasalazine (salicylazosulfapyridine)

Sulfur Dioxide

Male Reproductive Toxicity(01/29/1999)

Developmental Toxicity(07/29/2011)
Developmental Toxicity(01/29/1999)

SulindacFemale Reproductive Toxicity(01/29/1999)

Talc containing asbestiform fibers

Cancer (04/01/1990)

Tamoxifen and its salts

Cancer (09/01/1996)

Tamoxifen Citrate

Developmental Toxicity(07/01/1990)

Temazepam

Developmental Toxicity(04/01/1990)

Teniposide

Developmental Toxicity(09/01/1996)

TerbacilDevelopmental Toxicity(05/18/1999)

Teriparatide

Cancer (08/14/2015)

Terrazole

Cancer (10/01/1994)

Testosterone and its esters

Cancer (04/01/1988)

Testosterone Cypionate

Developmental Toxicity(10/01/1991)

Testosterone Enanthate

Developmental Toxicity(04/01/1990)

Tetrabromobisphenol A

Cancer (10/27/2017)

3,3',4,4'-Tetrachloroazobenzene

Cancer (07/24/2012)
Cancer (01/01/1988)

2,3,7,8-Tetrachlorodibenzo-p-dioxin (TCDD)

Developmental Toxicity(04/01/1991)

1,1,1,2-Tetrachloroethane

Cancer (09/13/2013)

1,1,2,2-Tetrachloroethane

Cancer (07/01/1990)

Tetrachloroethylene (Perchloroethylene)

Cancer (04/01/1988)

p-a,a,a-Tetrachlorotoluene

Cancer (01/01/1990)

Tetrachlorvinphos

Cancer (05/20/2016)

Tetracycline (internal use)

Developmental Toxicity(10/01/1991)

Tetracycline Hydrochloride (internal use)

Developmental Toxicity(01/01/1991)

Tetracyclines (internal use)

Developmental Toxicity(10/01/1992)

Tetrafluoroethylene

Cancer (05/01/1997)

4,4'-Methylene bis(N,N-dimethyl)benzenamine

Cancer (10/01/1989)

Tetranitromethane

Cancer (07/01/1990)

Thalidomide

Developmental Toxicity(07/01/1987)

Thioacetamide

Cancer (01/01/1988)

4,4'-Thiodianiline

Cancer (04/01/1988)

Thiodicarb

Cancer (08/20/1999)

Thioguanine

Developmental Toxicity(07/01/1990)

Female Reproductive Toxicity(05/18/1999)
Thiophanate Methyl

Male Reproductive Toxicity(05/18/1999)

Thiouracil

Cancer (06/11/2004)

Thiourea

Cancer (01/01/1988)

Thorium Dioxide

Cancer (02/27/1987)

Titanium dioxide (airborne, unbound particles of
respirable size)

Cancer (09/02/2011)

Tobacco Smoke

Cancer (04/01/1988)
Developmental Toxicity(04/01/1988)

Tobacco Smoke (Primary)Female Reproductive Toxicity(04/01/1988)
Male Reproductive Toxicity(04/01/1988)

Tobacco, oral use of smokeless products

Cancer (04/01/1988)

Tobramycin Sulfate

Developmental Toxicity(07/01/1990)
Developmental Toxicity(01/01/1991)

TolueneFemale Reproductive Toxicity(08/07/2009)

Toluene Diisocyanate

Cancer (10/01/1989)

o-Toluidine

Cancer (01/01/1988)

o-Toluidine Hydrochloride

Cancer (01/01/1988)

Topiramate

Developmental Toxicity(11/27/2015)

Toxaphene (Polychlorinated camphenes)

Cancer (01/01/1988)

Toxins derived from Fusarium moniliforme (Fusarium
verticillioides)

Cancer (08/07/2009)trans-2-[(Dimethylamino)methylimino]-5-[2-(5-nitro-2furyl)vinyl]-1,3,4-oxadiazole

Cancer (01/01/1988)

Treosulfan

Cancer (02/27/1987)
Developmental Toxicity(03/30/1999)

Triadimefon

Female Reproductive Toxicity(03/30/1999)
Male Reproductive Toxicity(03/30/1999)

Triamterene

Cancer (04/18/2014)

Triazolam

Developmental Toxicity(04/01/1990)

S,S,S-Tributyl phosphorotrithioate (Tribufos, DEF)

Cancer (02/25/2011)

Tributyltin Methacrylate

Developmental Toxicity(12/01/1999)

Trichlormethine (Trimustine Hydrochloride)

Cancer (01/01/1992)

Trichloroacetic Acid

Cancer (09/13/2013)

Vinyl trichloride (1,1,2-Trichloroethane)

Cancer (10/01/1990)
Cancer (04/01/1988)

Trichloroethylene

Developmental Toxicity(01/31/2014)
Male Reproductive Toxicity(01/31/2014)

2,4,6-Trichlorophenol

Cancer (01/01/1988)

1,2,3-Trichloropropane

Cancer (10/01/1992)

Trientine Hydrochloride

Developmental Toxicity(02/27/2001)

Triforine

Developmental Toxicity(06/18/1999)

Trilostane

Developmental Toxicity(04/01/1990)

Trimethadione

Developmental Toxicity(01/01/1991)

Trimethyl Phosphate

Cancer (05/01/1996)

2,4,5-Trimethylaniline and its strong acid salts

Cancer (10/24/1997)

Trimetrexate Glucuronate

Developmental Toxicity(08/26/1997)

2,4,6-Trinitrotoluene

Cancer (12/19/2008)
Cancer (07/01/1992)

Triphenyltin Hydroxide

Developmental Toxicity(03/18/2002)

Tris(1,3-dichloro-2-propyl) Phosphate (TDCPP)

Cancer (10/28/2011)

Tris(1-aziridinyl)phosphine Sulfide (Thiotepa)

Cancer (01/01/1988)

Tris(2,3-dibromopropyl)phosphate

Cancer (01/01/1988)

Tris(2-chloroethyl) Phosphate

Cancer (04/01/1992)

Trp-P-1 (Tryptophan-P-1)

Cancer (04/01/1988)

Trp-P-2 (Tryptophan-P-2)

Cancer (04/01/1988)

Trypan Blue (Commercial Grade)

Cancer (10/01/1989)

Unleaded Gasoline (Wholly Vaporized)

Cancer (04/01/1988)
Cancer (04/01/1988)
Developmental Toxicity(01/01/1992)

Uracil Mustard

Female Reproductive Toxicity(01/01/1992)

Male Reproductive Toxicity(01/01/1992)
Cancer (01/01/1988)
Urethane (Ethyl Carbamate)

Developmental Toxicity(10/01/1994)

Urofollitropin

Developmental Toxicity(04/01/1990)

Valproate (Valproic acid)

Developmental Toxicity(07/01/1987)

Vanadium pentoxide (orthorhombic crystalline form)

Cancer (02/11/2005)

Vinblastine Sulfate

Developmental Toxicity(07/01/1990)
Cancer (08/20/1999)

Vinclozolin

Developmental Toxicity(05/15/1998)

Vincristine Sulfate

Developmental Toxicity(07/01/1990)

Vinyl Bromide

Cancer (10/01/1988)

Vinyl chloride

Cancer (02/27/1987)
Cancer (07/01/1990)

Vinyl cyclohexene dioxide (4-vinyl-1-cyclohexene
diepoxide)

Female Reproductive Toxicity(08/01/2008)
Male Reproductive Toxicity(08/01/2008)

Vinyl Fluoride

Cancer (05/01/1997)

Cancer (05/01/1996)

4-Vinylcyclohexene

Female Reproductive Toxicity(08/07/2009)
Male Reproductive Toxicity(08/07/2009)
Developmental Toxicity(01/27/2017)

Vismodegib

Female Reproductive Toxicity(01/27/2017)
Male Reproductive Toxicity(01/27/2017)

Warfarin

Developmental Toxicity(07/01/1987)

Wood Dust

Cancer (12/18/2009)

2,6-Xylidine (2,6-Dimethylaniline)

Cancer (01/01/1991)

Zalcitabine

Cancer (08/07/2009)

Zidovudine (AZT)

Cancer (12/18/2009)
Cancer (12/22/2000)

Zileuton

Developmental Toxicity(12/22/2000)
Female Reproductive Toxicity(12/22/2000)