REFERENCE INFORMATION

R-070720

㼁㻿㻼 䝥䝺䝗䝙䝌䞁ᶆ‽㘄๣䛾ド᫂᭩ᨵゞ㻌㠀ᔂቯᆺ〇๣⁐ฟヨ㦂䛾✌ാᛶ⬟☜ㄆヨ㦂䛻⏝䛔䜛 USP 䝥䝺䝗䝙䝌䞁ᶆ‽㘄๣䛻䛴䛔䛶䚸䛭䛾⌧⾜䝻䝑䝖䛾つᐃ䛜
2007 ᖺ 7 ᭶ 16 ᪥௜䛷ᨵゞ䛥䜜䜎䛧䛯䚹෌ホ౯䛻ᇶ䛵䛝䚸⿦⨨ 2䠄䝟䝗䝹ἲ䠅䛾チᐜ⠊ᅖ䜢 37 % - 70 %䛛䜙 30 % - 57 %䛻ኚ᭦䛩䜛䛸䛔䛖䜒䛾䛷䛩䚹䛯䛰䛧䚸2007 ᖺ 7 ᭶ 16 ᪥௨๓䛻ᐇ᪋䛧䛯ヨ㦂䛻䛿㐺⏝䛥䜜䜎䛫䜣䚹䛺䛚䚸⌧ᅾ䛾チᐜ⠊ᅖ䛿 2007 ᖺ 7 ᭶ 30 ᪥䜢䜒䛳䛶↓ຠ䛻䛺䜚䜎䛩䚹௨ୗ䛻ᨵゞ䛥䜜䛯ド᫂᭩䛾࿴ヂ䜢グ㏙䛧䜎䛩䚹ཎᩥ䠄୍㒊┬␎䠅䛿ḟ䛾䝃䜲䝖䛛䜙ධᡭ䛩䜛䛣䛸䛜䛷䛝䜎䛩䚹
http://www.usp.org/referenceStandards/useAndStorage/calibrators.html----------------------------------------------------------------------------------------

USP ド᫂᭩
ὀグ䠖 䛣䛾᭩㠃䛻つᐃ䛥䜜䛯⠊ᅖ䛜䛣䛾䝻䝑䝖䛾ᚑ᮶䛾⠊ᅖ䛻⨨䛝᥮䜟䜛䠄᭷ຠ᪥䠖2007 ᖺ 7 ᭶ 30 ᪥䠅䚹

USP 䝥䝺䝗䝙䝌䞁㘄๣ RS
䝻䝑䝖 P0E203
䠄䝥䝺䝗䝙䝌䞁ྡ┠ྵ᭷㔞 10 mg䠅⁐ฟヨ㦂✌ാᛶ⬟☜ㄆヨ㦂⏝ᔂቯᆺ㘄๣
USP 䝥䝺䝗䝙䝌䞁㘄๣ RS 䛿䚸⁐ฟヨ㦂ἲ<711>䛚䜘䜃⸆≀ᨺฟヨ㦂ἲ<724>䛻㛵䛩䜛 USP ୍⯡ヨ㦂ἲ䛾㡯䛻グ㍕䛥䜜䛯 USP ⿦⨨ 1 䛚䜘䜃⿦⨨ 2 䛾⿦⨨㐺ྜᛶヨ㦂䛾䛯䜑䛻ᥦ౪䛥䜜䜛䜒䛾䛷䛒䜛䚹䛣䛾㘄๣䜢㐣ᗘ䛾‵Ẽ䛻᭚䛧䛶䛿䛺䜙䛺䛔䚹⁐ฟヨ㦂ᾮ㻌 䠉ḟ䛾䜘䛖䛻ヨ㦂ᾮ䜢ㄪ〇䛩䜛䛣䛸䜢᥎ዡ䛩䜛䚹㐺㔞䛾Ỉ䜢⦆䜔䛛䛻᧠ᢾ䛧䛺䛜䜙 41䉝䜎䛷ຍ 䛩䜛䚹Ꮝ
ᚄ 0.45 ȝm 䛾䝣䜱䝹䝍䜢⏝䛔䚸ᨩᢾᶵ䜢௜タ䛧䛯㐺ᙜ䛺䜝㐣䝣䝷䝇䝁䛻ῶᅽ䜝㐣䛩䜛䚹䝣䝷䝇䝁䜢ᐦᰦ䛧䚸᧠ᢾ䛧䛺䛜䜙᭦䛻 5 ศ㛫ῶᅽ䛩䜛䚹௚䛾 37䉝䛷᳨ド䛥䜜䛯⬺Ẽ᪉ἲ䜢⏝䛔䛶䜒䜘䛔䚹⁐ฟヨ㦂ᾮ䛾 ᗘ䛿ヨ㦂㛤ጞ๓䛻
37䉝䜢ୗᅇ䛳䛶䛿䛺䜙䛺䛔䚹ุᐃྛ䚻䛾⿦⨨䛾ィ⟬್䛜䛔䛪䜜䜒⾲䛻グ㍕䛥䜜䛯つᐃ⠊ᅖෆ䛻䛒䜜䜀㐺ྜ䛸䛩䜛䚹ᡭ㡰㻌 䠉⌧⾜ USP 䛾⁐ฟヨ㦂ἲ<711>䛚䜘䜃⸆≀ᨺฟヨ㦂ἲ<724>䜢ཧ↷䚹ὀ㔘䠖㻌 ᶆ‽⁐ᾮ⥲㔞䛾 5 %䜢㉸䛘䛺䛔㔞䛷䛒䜜䜀䜰䝹䝁䞊䝹䜢⏝䛔䛶䝥䝺䝗䝙䝌䞁ᶆ‽≀㉁䜢⁐ゎ䛧䚸⁐ฟヨ㦂ᾮ䛷ᕼ㔘䛧䛶䜒䜘䛔䚹䜝㐣䛾㐣⛬䛷⸆≀䛾྾╔䛻䜘䜛ᦆኻ䛜⏕䛨䛶䛿䛺䜙䛺䛔䚹⮬ື໬䛥䜜䛯᪉ἲ䛻䜘䛳䛶䜒䛯䜙䛥䜜䜛೫䜚䛿㑊䛡䜛䜉䛝䛷䛒䜛䚹ヨ㦂ჾ䛜୍䛴䛾⿦⨨䠄ᅇ㌿䝞䝇䜿䝑䝖ἲ䜎䛯䛿䝟䝗䝹ἲ䛾䛹䛱䜙䛛䠅ᑓ⏝䛺䛾䛷䛒䜜䜀䚸✌ാᛶ⬟䛾☜ㄆ䛿䛭䛾⿦⨨䛾䜏䛻ồ䜑䜙䜜䜛䚹ྛᐜჾ䛻䛴䛔䛶 30 ศ䛷⁐ฟ䛩䜛䝥䝺䝗䝙䝌䞁 C21H26O5䜢ᐃ㔞䛧䚸䝷䝧䝹⾲♧㔞䛻ᑐ䛩䜛ⓒศ⋡䛷⾲䛩䚹500 mL䛾⬺ẼỈ䜢⁐ฟヨ㦂ᾮ䛻⏝䛔䚸37䉝䛷ヨ㦂䜢ᐇ᪋䛩䜛䚹ྛ⿦⨨䛿 50 rpm 䛾㏿ᗘ䛷᧯స䛩䜛䚹30 ศᚋ䛻ヨᩱ䜢᥇ྲྀ䛧䛶䜝㐣䛧䚸⁐ฟ䛧䛯䝥䝺䝗䝙䝌䞁䛾㔞䜢 242 nm䠄ᴟ኱྾཰Ἴ㛗䠅䛷 ᐃ䛧䛶᪤▱⃰ᗘ䛾 USP 䝥䝺䝗䝙䝌䞁ᶆ‽⁐ᾮ䛸ẚ㍑䛩䜛䚹
1௨ୗ䛾್䛿䝻䝑䝖 P0E203 䛾䜏䛻㐺⏝䛥䜜䜛150 rpm 䛷 30 ศ㛫䛻⁐ฟ䛩䜛䝥䝺䝗䝙䝌䞁䛾㔞䠄䝷䝧䝹⾲♧㔞䛻ᑐ䛩䜛ⓒศ⋡䠅
47 – 82

230 – 57

⿦⨨

1820 ᖺ䛻๰タ䛥䜜䛯⡿ᅜ⸆ᒁ᪉఍㆟䛿⸆⛉኱Ꮫ䜔་⸆ရබⓗᶵ㛵䛾௦⾲⪅䛷ᵓᡂ䛥䜜䛶䛔䜛䚹ᮏ఍㆟䛿ἲⓗ䛻ㄆ䜑䜙䜜䛯⸆≀䛾බᐃᶆ‽䛸䛺䜛 USP-NF 䛾ᨵゞ䛸Ⓨ⾜䛻䛯䛪䛥䜟䛳䛶䛔䜛䚹䝥䝺䝗䝙䝌䞁㘄๣䠖✌ാᛶ⬟☜ㄆ䛻㛵䛩䜛ὀグఱᖺ䜒䠄3 ᖺ䡚5 ᖺ䠅᪥ᖖⓗ䛻౑⏝䛧䛶䛔䜛⁐ฟヨ㦂ჾ䛷⠊ᅖእ䛾್䛜ᚓ䜙䜜䛯䛸䛝䛻䛿ᩚഛ䛧䛺䛡䜜䜀䛺䜙䛺䛔䚹᪥ᖖⓗ䛻౑⏝䛩䜛⁐ฟヨ㦂ჾ䛿ዴఱ䛺䜛䜒䛾䛷䛒䛳䛶䜒ᐃᮇⓗ䛻᳨ド䛩䜉䛝䛷䛒䜛䚹⿦⨨䜢⛣㌿䛧䛯ሙྜ䛻䛿෌᳨ド䛜ᚲせ䛻䛺䜛䚹䛒䜛 USP ⁐ฟヨ㦂ἲ䛷䛿 2 L ௨እ䛾ᐜჾ䜔 50 rpm䚸100 rpm ௨እ䛾㏿ᗘ䛜せồ䛥䜜䛶䛔䜛䚹ヨ㦂ჾ䛜✌ാᛶ⬟☜ㄆヨ㦂䛻ྜ᱁䛩䜛䛾䛷䛒䜜䜀䚸䛭䛖䛧䛯௚䛾᮲௳䛻䜒㐺ྜ䛩䜛䚹✌ാᛶ⬟☜ㄆヨ㦂䛻䛚䛡䜛ㄗᕪཎᅉ䛾஦౛ヨ㦂ᾮ䛾⬺Ẽ㻌 ୙㐺ษ䛺⬺Ẽ䛿䜘䛟䛒䜛ၥ㢟䛷䛒䜛䚹ヨ䛜⏕䛨䛯䜚䚸䝥䝻䞊䝤䛛䜙䛾✵Ẽྤฟ䛾㝿䛻వศ䛺஘ὶ䛜⏕䛨䛯䜚䛩䜛䛣䛸䛜䛒䜛䚹䜎䛯䚸䝃䞁䝥䝸䞁䜾㛫䛷䜻䝱䝸䞊䜸䞊䝞䞊䛜⏕䛨䜛ྍ⬟ᛶ䜒䛒䜛䛾䛷䚸ὀព䛩䜛䚹⮬ື䝅䝇䝔䝮䛻ᕼ㔘ᶵ⬟䛜䛺䛟྾ගᗘ䛾ㄞྲ್ྀ䛜 1.0 AU 䜢㉸䛘䜛䛣䛸䛜䛒䜛䛛䜒䛧䜜䛺䛔䚹1.0 AU 䜢㉸䛘䜛┤⥺ᛶ䛿ᶆ‽ヨᩱ䛾᳨㔞⥺䛻䜘䜚❧ド䛩䜉䛝䛷䛒䜛䚹㦂ᾮ୰䛾⁐Ꮡ䜺䝇䛜ᩄឤ䛻స⏝䛩䜛䛣䛸䛿䛩䛷䛻❧ド䛥䜜䛶䛔䜛䚹⬺Ẽ᪉ἲ䛾୍౛䜢䛒䛢䜛䛸䚸ḟ䛾䛸䛚䜚䛷䛒䜛䚹ヨ㦂ᾮ䜢⦆䜔䛛䛻᧠ᢾ䛧䛺䛜䜙 41䉝䜎䛷ຍ 䛧䚸Ꮝᚄ0.45 ȝm 䛾䝣䜱䝹䝍䛷ᨩᢾᶵ䜢௜タ䛧䛯㐺ᙜ䛺䜝㐣䝣䝷䝇䝁䛻ῶᅽ䜝㐣䛩䜛䚹䝣䝷䝇䝁䜢ᐦᰦ䛧䚸᧠ᢾ䛧䛺䛜䜙᭦䛻 5ศ㛫ῶᅽ䛩䜛䚹ヨ㦂㛤ጞ๓䛻⁐ฟヨ㦂ᾮ䛜 37䉝䜢ୗᅇ䜙䛺䛔䜘䛖䛻䛩䜛䚹ヨ㦂ᾮ䜢ᐜჾ䛻┤᥋䚸✜䜔䛛䛻⛣䛩䚹37䉝䛾ᖹ⾮䜢ಁ㐍䛩䜛䛯䜑䛻⿦⨨ 2 䛾ᅇ㌿㍈䜢ᅇ㌿䛥䛫䜛䛾䛿㑊䛡䜛䜉䛝䛷䛒䜛䚹ヨ㦂ᾮ䛿䛝䛱䜣䛸ᖹ⾮䛻㐩䛧䛯ᚋ䛻౑⏝䛩䜛䚹㘄๣㻌 䝥䝺䝗䝙䝌䞁㘄๣䛿ඖ䛾཰⣡ჾ䛻ධ䜜䚸஝⇱䛧䛯ሙᡤ䛻ಖ⟶䛩䜉䛝䛷䛒䜛䚹㐣ᗘ䛾‵Ẽ䛿㑊䛡䜛䛣䛸䚹ヨ㦂䛾㝿䛻䛿䚸ᐜჾ䛛䜙ྲྀ䜚ฟ䛧䛯䜙┤䛱䛻⁐ฟヨ㦂䜢㛤ጞ䛩䜛䛣䛸䚹ᐜჾ㻌 ᐜჾ䛿Ύί䛷䛺䛡䜜䜀䛺䜙䛺䛔䚹ᐜㄆ䛷䛝䛺䛔ᐜᶆ‽ရ㻌 USP ᶆ‽ရ䛾⌧⾜䝻䝑䝖䜢౑⏝䛧䚸䝷䝧䝹䛻グ㏙䛥䜜䛯ᣦ♧䛻ᚑ䛳䛶ྲྀ䜚ᢅ䛖䛣䛸䚹ᶆ‽⁐ᾮ䛿౑⏝ᙜ᪥䛻㒔ᗘㄪ〇䛩䜛䛣䛸䚹ჾ䜢౑⏝䛩䜛䛸⣔⤫ㄗᕪ䛾ཎᅉ䛻䛺䜛䚹᣺ື䛸ᶵᲔⓗၥ㢟㻌 Ⅼ᳨䜔䝯䞁䝔䝘䞁䝇䛜୙㐺ษ䛺䛸䛝䚸䜝㐣㻌 ヨᩱ䜢㐲ᚰศ㞳䛧䛶䛿䛺䜙䛺䛔䚹ヨᩱ䛿᥇ྲྀᚋ┤⁐ฟ䝦䝑䝗䛾Ỉᖹᗘ䚸ᅇ㌿㍈䛾ᆶ┤ᗘ䚸㥑ື䝏䜵䞊䞁䜎䛯䛿㥑ື䝧䝹䝖䛾ఙᙇᗘ䚸୰ᚰᗘ䚸䜼䜰ᯈ䛾㐠㌿᮲௳䛸䛔䛳䛯せᅉ䛜⁐ฟ䛻ᑐ䛧䛶୙฼䛻స⏝䛩䜛䚹rpm 䛾䝕䝆䝍䝹ㄞྲྀ䛿ᚲ䛪䛧䜒ಶ䚻䛾㍈ᅇ㌿㏿ᗘ䜢♧䛩䛸䛿䛛䛞䜙䛺䛔䚹㍈䛜Ἴᡴ䛴䛣䛸䜢ಶ䚻䛻☜ㄆ䛩䜛䛻䛿┠どⓗ᳨ᰝ䛜ᚲせ䛻䛺䜛䛷䛒䜝䛖䚹᣺ື䛾ᙳ㡪䜢᭱ᑠ㝈䛻䛸䛹䜑䜛䛻䛿䚸⁐ฟヨ㦂ჾ䜢ሀᅛ䛺䝧䞁䝏䛛䝔䞊䝤䝹䛻ᤣ䛘௜䛡䜛䜉䛝䛷䛒䜛䚹䝣䜯䞁䚸䝫䞁䝥䚸䛭䛾௚䛾㟈ື※䛸䛺䜛ᶵᲔタഛ䛿㊥㞳䜢㞳䛧䛶タ⨨䛩䜛䛛䚸ఱ䜙䛛䛾᪉ἲ䛷㝸㞳䛩䜉䛝䛷䛒䜛䚹ᚠ⎔䝟䝍䞊䞁䛻䜘䛳䛶⏕䛨䜛Ỉᵴෆ䛾஘ὶ䛿୍䛴௨ୖ䛾ᐜჾ䛷䛾⤖ᯝ䛻ᙳ㡪䜢୚䛘䜛䛣䛸䛜䛒䜛䚹䛱䛻䜝㐣䛩䜉䛝䛷䛒䜛䚹䝣䜱䝹䝍䛿䜝㐣≀䛾ጉᐖ䜔⸆≀䛾྾╔䛻䜘䜛ᙳ㡪䛜䛺䛔䛛ㄪ䜉䛶䛚䛟ᚲせ䛜䛒䜛䚹ྛᐜჾ䛛䜙䛾䝃䞁䝥䝸䞁䜾䛻䛿ู䚻䛾Ύί䛺䝅䝸䞁䝆䛸䝣䜱䝹䝍䜢౑⏝䛩䜉䛝䛷䛒䜛䚹䝟䝗䝹䛸ᅇ㌿䝞䝇䜿䝑䝖㻌 䛹䛱䜙䛾⿦⨨䜒ᅇ㌿㍈䛿䜎䛳䛩䛠䛷䛺䛡䜜䜀䛺䜙䛺䛔䚹䛣䜜䜢⡆༢䛻᳨ᰝ䛩䜛䛻䛿䝧䞁䝏ୖ䛷᧠ᢾ⩼௜䛝䜎䛯䛿䝞䝇䜿䝑䝖䜢䛴䜚ୗ䛢䜛㐃⤖┙௜䛝䛾ᅇ㌿㍈䜢ᅇ㌿䛥䛫䜛䛣䛸䛷䛒䜛䚹䛣䛾䛸䛝䚸ᅇ㌿㍈䛿
▮㍈䛾䜘䛖䛻ᖹ➼䛻ᅇ䜛䛣䛸䛜ồ䜑䜙䜜䜛䚹䝞䝇䜿䝑䝖䛿䜎䛳䛩䛠䛷䛒䜚䚸䜋䛠䜜䛜䛒䛳䛶䛿䛺䜙䛺䛔䚹ሷ㓟ヨ㦂ᾮ䜢᪥ᖖⓗ䛻౑⏝䛩䜛䛸䝇䝔䞁䝺䝇䝇䝏䞊䝹〇䛾䝞䝇䜿䝑䝖䛜㗵䜃䜛䛣䛸䛜䛒䜛䛛䜙ὀព䛩䜛䚹䝞䝇䜿䝑䝖䛿ᅇ㌿㍈䛾㐃
⤖┙䛻䛧䛳䛛䜚䛸ྲྀ䜚௜䛡䛺䛡䜜䜀䛺䜙䛺䛔䚹⵨Ⓨ㜵Ṇ⵹䛿⏝䛔䜛䜉䛝䛷䛒䜛䚹౑⏝䛾㝿䛻䛿䚸䜄䛳䛯䜚䛸ྜ䛳䛶䛔⮬ື໬㻌 ศᯒἲ䜔䝃䞁䝥䝸䞁䜾ἲ䜢ྵ䜏⮬ື໬䛥䜜䛯䝅䝇䝔䝮䛿䚸୪⾜ᡭືヨ㦂䜢ᐇ᪋䛧䛶ྠ᫬䛻⁐ฟᾮ䜢᥇ྲྀ䛧䚸⮬ື䝅䝇䝔䝮䛾⤖ᯝ䛸ẚ㍑䛩䜛䛣䛸䛻䜘䜚䚸ᖖ䛻᳨ド䛩䜛䚹䝣䜱䝹䝍䛾䝥䝻䞊䝤䛻䛿ワ䜎䜚䜔άᛶᡂศ䛾྾╔2䜛䛛ṍ䜣䛷䛔䜛䛛Ⅼ᳨䛩䜛䛣䛸䚹䝷䝧䝹⾲♧ෆᐜ䠄ᣦ♧஦㡯䛾䜏䠅1 㘄䛒䛯䜚䛾䝥䝺䝗䝙䝌䞁ྡ┠ྵ㔞䛿 10 mg 䛷䛒䜛䚹㘄๣඲య䛣䜜௨ୖ䛾᝟ሗ䛻䛴䛔䛶䛿䚸www.usp.org 䜢ཧ↷䛾䛣䛸䚹䜢౑⏝䛩䜛䛣䛸䚹౑⏝䛩䜛๓䛻ᰂ䜙䛛䛔ๅẟ䜢⏝䛔䛶⾲㠃䛾䝂䝭䜢㝖ཤ䛩䜛䛣䛸䚹஝⇱䛧䛯ሙᡤ䛻ᐊ 䛷ಖ⟶䛩䜛䛣䛸䚹--------------------------------------------------------------------------------------------------------------------------------------------------------᭷ຠᮇ㝈㻌౑⏝ㄝ᫂㻌⌧⾜䛾䝻䝑䝖䛿බᘧ䛾 USP ᶆ‽ရ䜹䝍䝻䜾䛻Ⓩ㘓䛥䜜䛶䛔䜛䚹䛸䛝䛸䛧䛶䚸௨๓䛾䝻䝑䝖䛜䜎䛰බᘧ䛺䜒䛾䛸䜏䛺䛥䜜䜛䛣䛸䛜䛒䜛䚹䜒䛧䛭䛖䛷䛒䜜䜀䚸䛂௨๓䛾䝻䝑䝖䠋᭷ຠ౑⏝ᮇ㛫䛃䛾ḍ䛻グ㏙䛥䜜䛶䛔䜛䛿䛪䛷䛒䜛䚹㏻ᖖ䚸௨๓䛾䝻䝑䝖䛿䚸⌧⾜䝻䝑䝖౪⤥㛤ጞᚋ⣙ 1 ᖺ㛫䚸බㄆ䛾≧ែ䛻␃䜑⨨䛛䜜䜛䚹ᙜヱ䛾 USP 䜔 NF 䛾་⸆ရྛ᮲䜎䛯䛿⌧⾜ USP-NF 䛾䛂ヨ㦂䛸ศᯒ䛻㛵䜟䜛୍⯡せồ஦㡯䛃䛻グ㍕䛥䜜䛯ᣦ♧䛻ᚑ䛖䛣䛸䚹ᮏ䝻䝑䝖䛾䝷䝧䝹䛻グ㏙䛥䜜䛯ᣦ♧䛜⌧⾜USP-NF グ㍕䛾䜒䛾䛸␗䛺䜛ሙྜ䛿䚸䝷䝧䝹䛻グ㏙䛥䜜䛯ᣦ♧䛜➨ 11 ᮲グ㍕䛾ዴఱ䛺䜛ᣦ♧䛻䜒ඃඛ䛩䜛䚹་⸆ရྛ᮲௨እ䛾౑⏝㻌౑⏝䛩䜛䝻䝑䝖䛜⌧⾜䛾䜒䛾䛷䛒䜛䛛䛹䛖䛛䜢ุ᩿䛩䜛䛾䛿౑⏝⪅䛾㈐ົ䛷䛒䜛䚹᭱᪂᝟ሗ䜢☜ᐇ䛺䜒䛾䛻䛩䜛䛯
䜑䛻䚸USP 䛿බㄆ䝻䝑䝖䜢ᣦᐃ䛧䛯䛂බᘧ USP ᶆ‽ရ䜹䝍䝻䜾䛃䜢Ⓨ⾜䛧䛶䛔䜛䚹䛣䛾᝟ሗ䛿㝸᭶Ⓨ⾜䛾ண⣙㉎ㄞ᭩䛷䛒䜛䛂Pharmacopeial Forum䛃䛻グ㍕䛥䜜䛶䛔䜛䛜䚸USP䛾 Web 䝃䜲䝖 www.uso.org 䛛䜙䜒ධᡭ䛩䜛䛣䛸䛜䛷䛝䜛䚹䛣䛾ᶆ‽ရ䜢බᐃἲ௨እ䛻౑⏝䛩䜛ሙྜ䚸䛭䛾㐺ྜᛶ䛻䛴䛔䛶䛿၏୍౑⏝⪅䛜㈐௵䜢㈇䛖䚹

ἲⓗ㏻▱஦㡯
USP 䛿䛣䛾ド᫂᭩䛜ṇ☜䛷䚸᏶඲䛷䛒䜚䚸䜎䛯᭱᪂䛷䛒䜛䛣䛸䛻䛴䛔䛶䚸⾲᫂䜒ಖド䜒䛧䛺䛔䚹䜎䛯䚸USP 䛿᫂♧ⓗ䛛䚸㯲♧ⓗ䛛䚸ἲ䛷ᐃ䜑䜙䜜䛯䜒䛾䛛䜢ၥ䜟䛪䚸௚䛾ዴఱ䛺䜛ಖド䜒᫂☜䛻ྰㄆ䛩䜛䚹䛣䜜䛻䛿ၟᴗྍ⬟ᛶ䜔≉ᐃ䛾┠ⓗ䜈䛾㐺ྜᛶ䛻䛴䛔䛶䛾ゝእ䛾ಖド䜢ྵ䜐䛜䚸䛭䜜䛻㝈ᐃ䛥䜜䛺䛔䚹USP 䛿䛣䛣䛻ྵ䜎䜜䜛᝟ሗ䛜㢳ᐈ䛾せồ䛻㐺ྜ䛩䜛䛣䛸䜢ಖド䛧䛺䛔䚹USP 䛿䛭䛾䜘䛖䛺ㄗ䜚䜔₃䜜䛾⌮⏤䛷䚸୍ษ䛾㈐䜢㈇䜟䛺䛔䚹䠄2007 ᖺ 7 ᭶ 20 ᪥䠅䛣䛾࿴ヂ䛿ᐩᒣ⏘ᴗᰴᘧ఍♫䛜సᡂ䛧䛯䜒䛾䛷䛩䚹䛯䛰䛧䚸ㄗヂ䜔㑇₃䛜䛒䛳䛶䜒䚸䛭䛾㈐䜢㈇䛔䜎䛫䜣䚹䛈㻡㻟㻝㻙㻜㻜㻣㻞㻌 ኱㜰ᕷ໭༊㇏ᓮ䠐୎┠ 㻟㻙㻢㻌㼀㻱㻸㻌 㻜㻢㻙㻢㻟㻣㻝㻙㻞㻢㻟㻣㻌㻲㻭㼄㻌 㻌㻜㻢㻙㻢㻟㻣㻞㻙㻜㻤㻠㻟㻌݈‫ޛ‬ငಅఇࡸ˟ᅈ㼔㼠㼠㼜㻦㻛㻛㼣㼣㼣㻚㼠㼛㼥㼍㼙㼍㼟㻚㼏㼛㻚㼖㼜㻛㻌3