斉木業績
2021 年
1. Yoritaka A, Kobayashi Y, Hayashi T, Saiki S, Hattori N. Randomized double-blind placebocontrolled trial of hydrogen inhalation for Parkinson's disease: a pilot study. Neurol Sci
42:4767-4770, 2021
2. Uehara Y, Ueno SI, Amano-Takeshige H, Suzuki S, Imamichi Y, Fujimaki M, Ota N, Murase
T, Inoue T*, Saiki S*, Hattori N*. Non-invasive diagnostic tool for Parkinson’s disease bysebum RNA profile with machine learning. Sci Rep 11:18550, 2021, *Corresponding author
3. Tsunemi T, Oyama G, Saiki S, Hatano T, Fukae J, Shimo Y, Hattori N. Intrajejunal infusionof levodopa/carbidopa for advanced Parkinson’s disease: a systematic review. Mov Disord
36:1759, 2021
4. Nakamura A, Kurihara S, Takahashi D, Ohashi W, Nakamura Y, Kimura S, Onuki M, Kume
A, Sasazawa Y, Furusawa Y, Obata Y, Fukuda S, Saiki S, Matsumoto M*, Hase K*.
Symbiotic polyamine metabolism regulates epithelial proliferation and macrophage
differentiation in the colon. Nat Commun 12:2105, 2021
5. Ishiguro M, Li Y, Yoshino H, Daida K, Ishiguro K, Oyama G, Saiki S, Funayama M, Hattori
N, Nishioka K. Clinical manifestations of Parkinson's disease harboring VPS35 retromercomplex component p.D620N with long-term follow-up. Parkinsonism Relat Disord
84:139-143, 2021
6. Koinuma T, Hatano T, Kamagata K, Andica C, Mori A, Ogawa T, Takeshige-Amano H,Uchida W, Saiki S, Okuzumi A, Ueno SI, Oji Y, Saito Y, Hori M, Aoki S, Hattori N.
Diffusion MRI Captures White Matter Microstructure Alterations in PRKN Disease. JParkinsons Dis 11:1221-1235, 2021
7. Kataura T, Tashiro E, Nishikawa S, Shibahara K, Muraoka Y, Miura M, Sakai S, Katoha N,Totsuka M, Hattori N, Sasazawa Y, Onodera M, Shin-ya K, Saiki S, Imoto M*. A chemical
genomics-aggrephagy integrated method studying functional analysis of autophagy inducers.
Autophagy 17:1856-1872, 2021
2022 年
1. Kataura T, Sedlackova L, Otten EG, Kumari R, Shapira D, Scialo F, Stefanatos R, Ishikawa
KI, Kelly G, Seranova E, Sun C, Maetzel D, Kenneth N, Trushin S, Zhang T, Trushina E,Bascom CC, Tasseff R, Isfort RJ, Oblong JE, Miwa S, Lazarou M, Jaenisch R, Imoto M,
Saiki S, Chronakis MP, Manjithaya R, Maddocks ODK, Sanz A, Sarkar S, Korolchuk VI.
Autophagy is required for the maintenance of NAD. Dev Cell 57:2584, 2022, DOI:
org/10.1016/j.devcel.2022.10.008
2. Sasazawa Y, Souma S, Furuya N, Miura Y, Kazuno S, Kakuta S, Suzuki A, Hashimoto R,
Hirawake-Mogi H, Date Y, Imoto M, Ueno T, Kataura T, Korolchuk VI, Tsunemi T, Hattori
N, Saiki S*. Oxidative stress-induced phosphorylation of JIP4 regulates lysosomal
positioning in coordination with TRPML1 and ALG2. EMBO J 41:e111476, 2022 PMID:36394115, DOI: 10.15252/embj.2022111476
3. Nakazato T, Kanai K, Kataura T, Nojiri S, Hattori N, Saiki S*. Plasma taurine is an axonal
excitability-translatable biomarker for amyotrophic lateral sclerosis. Sci Rep 12:915, 2022,*Corresponding author PMID: 35650294, DOI: 10.1038/s41598-022-13397-6
2023 年
Miyamoto K, Saiki S*, Matsumoto H, Suzuki A, Yamashita Y, Iseki T, Ueno SI, Shiina K,
Kataura T, Kamagata K, Imamichi Y, Sasazawa Y, Fujimaki M, Akamatsu W, Hattori N*.

Systemic metabolic alteration dependent on the thyroid-liver axis in early PD. Ann Neurol
93:303-316, 2023 *Corresponding author