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Safety Data Sheet
1. Chemical product and company identification
Product name: PGMEA

Company information
Name of manufacturerAddress
Name of section
Telephone number
Facsimile number
Mail address
Reference No： KANTO CHEMICAL CO., INC.
： 2-1, Nihonbashi, Muromachi 2-Chome, Chuo-Ku, Tokyo, 103-0022, Japan： Electronic materials division technical department： +81-3-6214-1080： +81-3-3241-1043： el-info@kanto.co.jp: GE00058 1.0

Recommended uses andrestrictions: Electronic chemicals

2. Hazards identification
GHS classification
Physical hazards

Flammable liquids

Category 3

Health hazards

Serious eye damage/eyeirritation

Category 2BSpecific target organ toxicity(single exposure)

Category 3 (narcosis)

Specific target organ toxicity(single exposure)

Category 3 (respiratory tract irritation.)

Hazardpictograms

Signal word:

Warning

Hazard statements:

Flammable liquid and vapor
Causes eye irritation
May cause respiratory irritation
May cause drowsiness or dizziness:

Keep away from heat, hot surfaces, sparks, open flames and otherignition sources. No smoking.
Keep container tightly closed.
Ground and bond container and receiving equipment.
Use explosion-proof electrical/ventilating/lighting equipment.
Use only non-sparking tools.
Take action to prevent static discharges.
Avoid breathing mist/vapors.
Wash hands, forearms and face thoroughly after handling.
Use only outdoors or in a well-ventilated area.
Wear protective gloves/protective clothing/eye protection/faceprotection.

Precautionary statements
Prevention

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IF ON SKIN (or hair): Take off immediately all contaminatedclothing. Rinse skin with water .
IF INHALED: Remove person to fresh air and keep comfortable forbreathing.
IF IN EYES: Rinse cautiously with water for several minutes.
Remove contact lenses, if present and easy to do. Continue
rinsing.
Call a POISON CENTER or doctor if you feel unwell.
If eye irritation persists: Get medical advice/attention.

Storage:

Store in a well-ventilated place. Keep container tightly closed.
Store in a well-ventilated place. Keep cool.
Store locked up.

Disposal:

Dispose of contents/container to hazardous or special waste
collection point, in accordance with local, regional, national
and/or international regulation.

3. Composition/information on ingredients
Distinction of substance ormixture:Substance

Synonyms:

2-Methoxy-1-methylethyl acetate、PGMEA、Propylene glycol
monomethyl ether acetate

Chemical name
2-Acetoxy-1methoxypropane

Concentration (%)
min. 99.5

Formula
CH3OCH2CH(OCOCH3)CH3

TSCA
ListedEC-No.
203-603-9

CAS RN
108-65-6

4. First aid measures
First aid measures
First-aid measures afterinhalation:

Remove the victim to fresh air, and make him blow his nose andgargle.

First-aid measures after skincontact:

Wash the affected areas under running water.

First-aid measures after eye
contact:

Wash the affected areas under running water for at least 15
minutes. If necessary, get medical treatment.

First-aid measures afteringestion:

The chemical is volatile. Do not induce vomiting because it
increases the risk of aspiration into the lungs. Get medical
attention immediately. If necessary, rinse mouth with water.

Personal Protection in FirstAid and Measures:

Rescuers should wear proper protective equipment like rubber
gloves, goggles.

Suitable extinguishing media:

Dry chemical powder, carbon dioxide, dry sand, foam

Unsuitable extinguishing media:

Water spray

Firefighting instructions:

Move containers from fire area if it can be done without risk, if
not possible, apply water from a safe distance to cool andprotect surrounding area.

5. Fire fighting measures

Fight fire from windward.
Dry chemical powder, carbon dioxide or dry sand should be used
for small fires. Foam extinguisher is effective for a large scale<< GE00058 PGMEA >>Page3/7Issue date: 6/4/2009
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fire.
Personal protection (Emergencyresponse):

Wear breathing apparatus.

6. Accidental release measures
Personal Precautions, Protective Equipment and Emergency Procedures
General measures:

Wear proper protective equipment and avoid contact with skin andinhalation of vapor. Conduct operations from upwind and evacuate
people downwind. Keep away personnel except for authorized ones
from spillage area by stretching ropes.

:

Attention should be given to avoid damage to the environment byflowing of spillage to rivers.

Environmental precautionsEnvironmental precautions

Methods and Equipment for Containment and Cleaning up
For containment:

Absorb spill with inert material （e.g, diatomaceous earth,sand） and flush spillage area with copious amounts of water.

Prevention Measures for
Secondary Accidents:

Remove nearby sources of ignition and prepare extinguishingmedia.

:

Wear proper protective equipment to avoid contact with skin or
inhalation of vapor. Fire is strictly prohibited.

7. Handling and storage
Handling
Technical measures

Ventilate well at working places.
Precautions for safe handling:

Avoid formation of vapor and aerosols.
Do not allow contact with oxidizing substances.

Storage
Storage conditions:

Store the bottle tightly closed in a cool, dark place because thesubstance is hygroscopic.

Material used inpackaging/containers:

Glass, stainless steel.
Do not use polyvinyl chloride resin, polystyrene.

8. Exposure controls / Personal protection equipment
ACGIH TWA

Not established

Appropriate engineering
controls
Protective equipment: Use with an enclosed system or a local exhaust ventilation.

Respiratory protection: If necessary, wear chemical cartridge respirator with an organic
vapor cartage

Hand protection: Impervious protective gloves

Eye protection: Safety goggles

Skin and body protection: Protective clothing, protective boots

9. Physical and chemical properties
Physical state: Liquid<< GE00058 PGMEA >>

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Color: Colorless.

Odor: AromaticpH: No data available

Melting point: -66 °C

Freezing point: No data available

Boiling point: 146 °C

Flash point: 42 °C (C.C.)

Auto-ignition temperature: 354 °C

Decomposition temperature: No data available

Flammability: Flammable

Vapor pressure: 0.5 kPa (20℃)

Relative density: No data availableDensity: 0.968 g/cm³ (20℃)

Relative gas density: 4.6Solubility: Water: 19.8 g/100ml (20℃)

Partition coefficient noctanol/water (log Pow)

: 0.56

Explosive limits (vol %): 1.5 – 7.0 vol % (200℃) (in air)

Viscosity, kinematic:: 1.23 mm²/s (20℃)

Particle characteristics: No data available

10. Stability and reactivity
Reactivity: May react with oxidizing substances.

Chemical stability: Stable under normal conditions. Hydroscopic.

Possibility of hazardous
reactions: Stable under normal conditions of use.

Conditions to avoid: Light, heat, moisture.

Incompatible materials: Oxidizing substances.

Hazardous decomposition
products: Carbon monoxide.

11. Toxicological information
Acute toxicity (oral)
Acute toxicity (dermal)
Acute toxicity (inhalation)

Skin corrosion/irritation: No classification
rat LD50>10000 mg/kg: No classification
rabbit LD50>5000 mg/kg: No classification (gas)Classification not possible (vapor)
Classification not possible (dust, mist): No classification
No detailed information is available other than descriptions thatthe substance was not irritating based on the primary skinirritation index of 0.0 obtained from rabbit tests, and that thesubstance caused slight irritation or cutaneous irritation. Basedon JIS classification criteria, the substance was classified into
"No classification".

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Serious eye damage/irritation:

Respiratory sensitization
Skin sensitization::

Germ cell mutagenicity:

Carcinogenicity
Reproductive toxicity::

STOT-single exposure:

STOT-repeated exposure
Aspiration hazard::

Causes eye irritationIn a test involving 9 rabbits, conjunctival redness, chemosis,iritis and corneal opacity were observed following application of
the substance. Mean scores were 0.8, 0.5, 0.1 and 0.2,respectively. All signs of irritation disappeared after 4 days. The
effects were judged to be "slightly irritating". The substance wasconclusively estimated to be slightly to moderately irritating.
Based on these data, the substance was classified into category 2B.
Classification not possible
No classification
Several tests using guinea pigs (Magnusson-Kligman maximization
tests and the method of Maguire) concluded that the substance did
not produce sensitization. Based on these results, the substancewas classified into "No classification".
Classification not possible
Although in vitro mutagenicity tests (Ames tests and chromosomal
aberration tests) yielded negative results (Toxicity Testing
Reports of Environmental Chemicals (Chemicals Investigation
Promoting Council), there were no in vivo test data available.
Thus, classification is not possible.
Classification not possible
No classification
In combined repeated oral dose toxicity study with thereproduction/developmental toxicity tests using rats, body weightgain was significantly suppressed in parents of both sexes, but nosignificant differences from control were observed in indices thatmeasure reproductive functions of parents, fertility, anddevelopment of the offspring. In addition, in oral administration
tests using pregnant rats during the organogenetic period, noeffects were observed on development of the offspring including
teratogenicity. As results suggested no adverse effects on
reproductive functions, fertility, and development of the offspring
including teratogenicity, the substance was classified into "Noclassification".
May cause drowsiness or dizziness
May cause respiratory irritation
In an oral test in rats, observations included lethargy at all
doses (500 - 10000 mg/kg). In a dermal test in rabbits, narcotic
effects were also found as the main symptoms. In a 2-weekinhalation test with mice, an acute change, degeneration ofolfactory epithelium in the nasal cavities, occurred at dose levelsof 16.2 mg/L and higher concentrations and the effect was more
severe and more extensive in a dose-related manner. An inflammatory
exudate was found in the lumen of the nasal cavities in someanimals. Based on these data, the substance was classified into
category 3 (narcosis, respiratory tract irritation).
Classification not possible
Classification not possible

12. Ecological information
Ecotoxicity
Aquatic acute
Aquatic chronic: No classification
Oryzias LC50＞100 mg/L/96h: No classification

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Persistence and degradability
No additional information available
Bioaccumulative potential
Low bioconcentrationlog Pow : 0.56
Mobility in soilHigh mobility
Koc : 2.3
Hazardous to the ozone layerOzone: Classification not possible

13. Disposal considerations
Ecological waste information: Burn in a chemical incinerator equipped with an afterburnerand a scrubber. Or entrust approved waste disposal companies
with the disposal.

Contaminated container andpackaging: In case of disposal of empty bottles, dispose bottles after
removing the content thoroughly.

14. Transport information
International Regulations
Transport by sea(IMDG)
UN-No. (IMDG)
Proper Shipping Name (IMDG)
Packing group (IMDG)
Transport hazard class(es)(IMDG)Air transport(IATA)
UN-No. (IATA)
Proper Shipping Name (IATA)
Packing group (IATA)
Transport hazard class(es)(IATA)::::

1993
FLAMMABLE LIQUID, N.O.S.
III
3::::

1993
Flammable liquid, n.o.s.
III
3Marine pollutant: Not applicable
Transport in bulk according to Annex II of MARPOL 73/78 and the IBC Code
Pollutant category:Z
MFAG-No:128

15. Regulatory information
Regulatory information with regard to this substance in your country or region should be examined byyour own responsibility.

16. Other information
Data sources: NITE Chemical Risk Information Platform (NITE-CHRIP), National
Institute of Technology and Evaluation.
Dictionary of Organic Compounds, The society of Synthetic
Organic Chemistry, Kodansha Ltd.（1985）.
Handbook of 17524 Chemical Products, The Chemical Daily Co.
（2024）.

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The information contained herein is based on several references and the present state of ourknowledge. However the SDS does not always cover all information about the product, handle theproduct carefully.The information is intended to ordinary usage, in case of particular handlings,
conduct appropriate safety measurements.The information herein is only provision of information, andit does not represent a guarantee the properties of the product.The Safety Data Sheet(SDS) is
prepared based on JIS Z7253.