Imaging in Liquid onJupiter XR AFM
Imaging in liquid on the Jupiter™ XR AFM is enabled by the use of a liquid compatible cantilever
holder and blueDrive™ technology. Imaging is simple to set up, stable over time, and results in highquality images of a wide range of samples such as molecules, biomaterials, and various coatings.

Liquid environment experiments
From DNA molecules, to proteins, to devices that need tostay hydrated, the liquid compatible cantilever holder andblueDrive technology enable liquid imaging on Jupiter XR
AFM. High resolution data can be acquired in water, buffer
or other liquids.

a)blueDrive Photothermal Excitationa) Liquid compatible cantilever holder with a dedicated ID moduleb) liquid cantilever holder equipped with a protective membrane
mounted on the Z scanner

Asylum Research’s exclusive blueDrive technology improvesb)

tapping mode-based imaging techniques by replacing

Imaging in Liquid on Jupiter XR

piezoacoustic excitation of the cantilever with photothermal

The Jupiter XR liquid cantilever holder is made fromexcitation. With blueDrive, cantilever tuning is clean andchemically inert PEEK and is equipped with a Viton®

avoids the so-called “forest of peaks” as shown in the figure

membrane to create a semi-sealed environment when usedbelow. Having only one peak simplifies the tuning procedure

with the CellLite sample holder. The membrane preventsand speeds up the experimental setup. Additionally, unlike

evaporation during experiments and protects the Z scanner

piezoacoustic drive, blueDrive is both stable over time,from contact with liquid. The liquid cantilever holder has aenabling extended periods of data collection without anydedicated ID module which plugs in the AFM and allows foradjustments by the user, and lower noise.

automatic software identification, quick setup, and use.

a) blueDrive concept, sketch (left), actual top-view optical image(right) showing the laser focus positions.

b) Comparison of tunes performed in liquid using piezo drive (left)
which exhibits the “forest of peaks” and blueDrive (right) with asingle resonance peak. Red trace is the thermal response of thecantilever, black trace is the cantilever tune, and blue trace is thephase response.

DNA on mica in buffer. Imaged with AC40 + blueDrive.
(4.88 Hz, 512 × 512, 400 nm)
1

Accessory chuck for safe accessory operationSpecifications

The accessory chuck has an embedded ID chip, which is automatically

The Jupiter XR liquid imaging kit includes

recognized by the software to simplify the experimental setup. Thea liquid compatible cantilever holder,

accessory chuck provides a stable XY scanner attachment base for thea protective Viton membrane, and aaccessories and its flexible membrane protects the AFM from accidental

CellLite sample holder. Liquid imagingliquid spills.

on Jupiter XR also requires an accessory
chuck that can be shared with othera)b)b

environmental control accessories.
Sample compatibility• Samples up to 30 mm diameterand 5 mm thickness• Supports up to 10 mmsample translation
Cleaning• Cantilever holder
Removable clamp for cleaninga) Accessory chuck placed on the XY scanner b) Close up view of the CellLite fluid
dish mounted on the accessory chuck.

Wipe with alcohol
Do not fully immerse in fluid• CellLite

CellLite Fluid Dish Sample Holder

Easy and complete disassembly
Autoclavable

The CellLite is a fluid dish designed to accommodate samples up to35 mm in diameter. A Viton membrane attaches to the liquid cantilever

System compatibility

holder, aligns and rests on the CellLite to serve as an evaporation shield

Jupiter XR

during experiments. CellLite can accommodate a larger volume ofliquid, compared to the droplet technique, which simplifies the setup
and allows for experimental versatility. Since there are no ports to beplugged, accidental leakage is minimized. The dish is made of PEEK forchemical resistance and the O-rings are FKM (Viton equivalent).

CellLite fluid dish mounted on the accessory chuck

The foregoing brochure is copyrighted by Oxford Instruments Asylum Research, Inc. Oxford
Instruments Asylum Research, Inc. does not intend the brochure or any part thereof to form part ofany order or contract or regarded as a representation relating to the products or service concerned,
but it may, with acknowledgement to Oxford Instruments Asylum Research, Inc., be used, applied or
reproduced for any purpose. Oxford Instruments Asylum Research, Inc. reserves the right to alter,without notice the specification, design or conditions of supply of any product or service. 3/2020

Oxford Instruments
Asylum Research Inc.
6310 Hollister Avenue
Santa Barbara, CA 93117

Phone +1-805-696-6466
https://AFM.oxinst.com
AFM.info@oxinst.com