The 46th Annual Meeting of The Japanese Society for Immunology
Submission ID

Program No.

Oral Presentation Time

Submission ID order

1st Author

Affiliation

Title

Date

Time

Venue

Session Title

Chair1Chair2
SachikoTakamura(Akashi)

100002 1-B-W4-9-O/P

Presentation: 7min,
Discussion: 2min

Toshihiko
Kobayashi

Department of Molecular Immunology &amp;
Inflammation, Research Institute, NCGM

Regulatory role of an oligopeptide transporter SLC15A3 during the systemic inflammation

Dec. 12(Tue.), 201714:55-16:15

Room B

Endogenous innate immunity
and inflammation-2

Osamu
Takeuchi

100007 1-H-W16-3-O/P

Presentation: 6min,
Discussion: 2min

Takashi Izawa

Department of Orthodontics and Dentofacial
Orthopedics, Tokushima University Graduate
School of Biomedical Sciences, Tokushima,
Japan

Crosstalk between cytokine RANKL and AhR signaling in osteoclasts controls bonehomeostasis

Dec. 12(Tue.), 201714:55-16:15

Room H

Cytokines and chemokines-2

Takayuki
YoshimotoTakashi
Kobayashi

100009 1-I-W18-7-O/P

Presentation: 7min,
Discussion: 3min

Kota Kokubo

Department of Immunology, Graduate School of <strong>Menin controls the memory Th2 cell function by maintaining the epigenetic integrity
Medicine, Chiba University, Chiba, Japanof Th2 cells.</strong>

Dec. 12(Tue.), 201714:55-16:15

Room I

Helper T cells

Masakatsu
YAMASHITA

Motoko Y.
KIMURA

100010 1-I-W17-1-O/P

Presentation: 7min,
Discussion: 3min

Yuki Hitomi

Department of Human Genetics, Graduate
School of Medicine, the University of Tokyo,
Tokyo Japan

Dec. 12(Tue.), 201713:20-14:40

Room I

Human Immunology

Koji Yasutomo Keishi Fujio

100011 1-I-W17-7-P

Poster Presentation

Tomonori Hayashi

Department of Molecular Biosciences, Radiation <strong>Relationship between T-cell Frequencies before Vaccination, Cytokine Levels, andEffects Research Foundation, Hiroshima, Japan Influenza Vaccine Response</strong>

Dec. 12(Tue.), 2017

Odd Number / 16:30-17:30, Exhibition
Human Immunology
Even Number / 17:30-18:30 Hall

Koji Yasutomo Keishi Fujio

100012 2-B-W20-2-O/P

Presentation: 7min,
Discussion: 3min

Takeshi Machida

Department of Immunology, Fukushima Medical <strong>Significant role for splenic marginal zone B cells in anti-dsDNA autoantibody
University, Fukushima, Japanproduction in lupus-prone mice with an MRL background</strong>

Dec. 13
14:25-15:45(Wed.), 2017

100013 1-D-W7-11-P

Poster Presentation

Motomi Yamazaki

Department of Gastroenterology, Nihon
University School of Medicine

Effects of H1N1 influenza virus infection on maternal and fetal in pregnant mouse

Dec. 12(Tue.), 2017

100014 1-C-W5-9-P

Poster Presentation

Yusei Miyazaki

Hokkaido Medical Center, Sapporo, Japan<strong>Fingolimod induces BAFF and expands circulating transitional B cells without
activating memory B cells and plasma cells in multiple sclerosis</strong>

100015 3-I-W42-5-O/P

Presentation: 7min,
Discussion: 3minHonglian Tong

Division of Molecular and Cellular
Immunoscience, Department of Biomolecular
Sciences, Faculty of Medicine, Saga University,
Saga, Japan

100016 1-H-W16-10-P

Poster Presentation

Munehiro
Yamaguchi

Department of Internal Medicine, Division ofAllergology and Respiratory Medicine, School of
Medicine, Showa University, Tokyo, Japan

100017 2-H-W24-8-P

Poster Presentation

Risa Nakamura

Department of Parasitology, NEKKEN, Nagasaki
Type 2 innate lymphoid cells exacerbate severe amebic liver abscess in mice
University, Nagasaki, Japan

Dec. 13
16:00-17:00(Wed.), 2017

Exhibition Immune response to parasite Yoichi
infections
Hall
Maekawa

100018 2-I-W25-1-O/P

Presentation: 7min,
Discussion: 3min

Tomofumi Uto

Division of Immunology, Department of
Infectious Diseases, Faculty of Medicine,
University of Miyazaki, Miyazaki, Japan

Critical role of plasmacytoid dendritic cells in the induction of oral tolerance for the control ofallergic sensitization

Dec. 13
14:25-15:45(Wed.), 2017

Room I

Dendritic cells andMacrophages-1: Organspecific Immune Tolerance

Satoshi Ishido

Kenichi Asano

100019 2-F-W22-14-O/P

Presentation: 8min,
Discussion: 3min

Osamu Kaminuma Yamanashi

Establishment of non-transgenic monoclonal T cell receptor-expressing mice

Dec. 13
14:25-15:45(Wed.), 2017

Room FT cell-1: T cell development
and repertoire selection

TaishinAkiyamaTakeshi Nitta

100020 2-H-W24-13-P

Poster Presentation

Motoko Morimoto

School of Food, Agricultural, and Environmental
Antibiotic-induced changes in the intestinal microbiota affect the host resistance against
Sciences, Miyagi University, Sendai City, Miyagi,
helminths in murine small intestineJapan

Dec. 13
16:00-17:00(Wed.), 2017

Exhibition Immune response to parasite Yoichi
infections
Hall
Maekawa

100021 3-H-W40-4-P

Poster Presentation

Kensuke
Yanashima

Atopy (Allergy) Research Center, Juntendo
University Graduate School of Medicine, Tokyo,
Japan

Dec. 14(Thu.), 2017

Odd Number / 16:00-17:00, Exhibition
Granulocyte & Mast cells
Even Number / 17:00-18:00 Hall

Atsuhito Nakao

100022 3-I-W43-13-O/P

Presentation: 7min,
Discussion: 3min

Junpei Suzuki

Department of Hematology, Clinical Immunology<strong>The tumor suppressor menin epigenetically regulates CD8 T cell senescence via
and Infectious Diseases, Ehime University
the modulation of glutamine metabolism</strong>
Graduate School of Medicine, Ehime, Japan

Dec. 14(Thu.), 201714:25-15:45

Room IT cell-3 : T cell function

Harumi Suzuki Ei Wakamatsu

100023 3-G-W38-2-O/P

Presentation: 7min,
Discussion: 4min

Maiko Okumura

1st Department of Internal Medicine, Graduate
School of Medicine and Pharmaceutical
Sciences (Medicine), University of Toyama

Production of Ro52/TRIM21 autoantibodies that react to PEP08 epitope in Ro52 clinicallyrelate to the morbidity and severity of interstitial lung disease in connective tissue diseases.

Dec. 14(Thu.), 201712:50-14:10

Room G

Systemic autoimmune
disease (2)Yoshiya Tanaka

Masayuki
Nishide100024 1-D-W8-5-O/P

Presentation: 6min,
Discussion: 2.5min

Eiji SHINYA

Nippon Medical School, Tokyo, Japan

Hematopoietic cell kinase (Hck) augmented the interaction between HIV-1 Nef and
SERINC5, which might promote HIV-1 infection by excluding SERINC5 from virion
incorporation in immature dendritic cells

Dec. 12(Tue.), 201714:55-16:15

Room D

Virus infection-2

Takashi Fujita

HiroyukiOshiumi100025 2-I-W25-8-P

Poster Presentation

Yasuyuki Negishi

Department of Microbiology and Immunology,
Nippon Medical School, Tokyo, Japan

Adoptive transfer of innate immune cells induce murine fetal loss

Dec. 13
16:00-17:00(Wed.), 2017

Exhibition Dendritic cells andMacrophages-1: OrganHall
specific Immune Tolerance

Satoshi Ishido

Kenichi Asano

100026 1-G-W13-1-P

Poster Presentation

Ikuo Nobuhisa

Department of Stem Cell Regulation, Medical
Research Institute, Tokyo Medical and Dental
University (TMDU), Tokyo, Japan

Role of adhesion molecules induced by a transcription factor Sox17 in intra-aortic
hematopoietic cell cluster formation in midgestation mouse embryos

Dec. 12(Tue.), 2017

Odd Number / 16:30-17:30, Exhibition Hematopoiesis and immune
environments
Even Number / 17:30-18:30 Hall

TakashiNagasawa

HitoshiTakizawa

100027 3-C-W30-5-P

Poster Presentation

Hirofumi Miyazaki

Department of Organ Anatomy, Graduate School FABP7 is involved in the M2 polarization of macrophages via mitochondrial fatty-acidof Medicine, Tohoku University
oxidation

Dec. 14(Thu.), 2017

Odd Number / 16:00-17:00, Exhibition Dendritic cells andTomohiko
Macrophages-2: Development
Even Number / 17:00-18:00 Hall
Tamuraand Recognition

Masafumi
Nakayama

100028 3-C-W31-17-P

Poster Presentation

Aya Ushio

Department of Oral Molecular Pathology,
Graduate school of Biomedical Sciences,
Tokushima University, Tokushima, Japan

Dec. 14(Thu.), 2017

Odd Number / 16:00-17:00, Exhibition Dendritic cells andTsuneyasu
Macrophages-3: Inflammatory
Even Number / 17:00-18:00 Hall
KaishoResponses

Rikinari
Hanayama

Center for Life Science Research, University of

Identification of the disease causal variants in human primary biliary cholangitis (PBC)
susceptibility gene loci <em>NFKB1/MANBA</em>

Hitoshi
Kohsaka

Shinsuke
YasudaOdd Number / 16:30-17:30, Exhibition
Virus infection-1
Even Number / 17:30-18:30 Hall

Taro Kawai

Mitsutoshi
Yoneyama

Dec. 12(Tue.), 2017

Odd Number / 16:30-17:30, Exhibition Tissue-specific immune
diseases I
Even Number / 17:30-18:30 Hall

Mitsuru
Matsumoto

Daisuke
Kamimura

Apaf1 plays a negative regulatory role in T cell responses by suppressing activation of
antigen-stimulated T cells

Dec. 14(Thu.), 201712:50-14:10

SatoshiMatsudaTadashiYokosuka

IL-34 induces lung fibrosis via M2 macrophages differentiation in mouse lung injured modelDec. 12(Tue.), 2017

Odd Number / 16:30-17:30, Exhibition
Takayuki
Cytokines and chemokines-2
Even Number / 17:30-18:30 Hall
Yoshimoto<strong>Synthetic host defense peptide IDR-1018 activates various functions of humanmast cells</strong>

CCL22-producing resident macrophages enhances autoimmune lesions in a mouse modelof Sj&ouml;gren&rsquo;s syndrome

1 / 30

Room B

Room I

Systemic autoimmune
disease (1)T cell-2 : T cell signaling

Takashi
Kobayashi
Masahiro
Yamamoto

Masahiro
Yamamoto
YosukeKurashima

The 46th Annual Meeting of The Japanese Society for Immunology
Submission ID

Program No.

Oral Presentation Time

1st Author

Submission ID orderAffiliation

Title

Date

Time

Venue

Session Title

Chair1Chair2

Hiroaki Ikeda

Koji Tamada

Naganari
OhkuraTakashi Sekiya

Kenji Izuhara

Koubun Yasuda

100029 2-C-W21-10-P

Poster Presentation

Soki Kashima

Department of immunology, Institute for Frontier
WT1-specific CTLs regenerated from T cell derived iPS cells exert therapeutic effect inLife and Medical Sciences, Kyoto University,
xenograft model of renal cell carcinoma
Kyoto, Japan

100030 3-A-W27-14-O/P

Presentation: 10min,
Discussion: 3min

Hiroki Satooka

Department of Fundamental Biosciences, Shiga The ERM protein moesin regulates CD8<sup>+</sup> regulatory T cell homeostasis andUniversity of Medical Science, Shiga, Japan
self-torelance

Dec. 14(Thu.), 201714:25-15:45

100031 1-A-W1-13-P

Poster Presentation

Chika Kanamori

Department of Animal medical science, Facultyof Life science, Kyoto Sangyo University, Kyoto,Japan<strong>Effects of Cryptomeria Japonica pollen and cigarette smoke on immune
cells</strong>

Dec. 12(Tue.), 2017

Odd Number / 16:30-17:30, Exhibition Allergy-1 : Lower airway
allergic inflammation
Even Number / 17:30-18:30 Hall

100032 3-D-W32-16-P

Poster Presentation

Naosuke Morikawa Osaka University, Osaka, Japan

Graduate School of Pharmaceutical Sciences,<strong>LY341495, an mGluR2/3 antagonist, attenuates the immunosuppressive functionof myeloid-derived suppressor cells and inhibits the melanoma tumor growth.</strong>

Dec. 14(Thu.), 2017

Odd Number / 16:00-17:00, Exhibition Tumor immunology-1 (Tumor Yutaka
antigens, antigen presenting
Even Number / 17:00-18:00 Hall
Kawakami
cells, anti-tumor T cells)

Hirokazu
Matsushita

100033 3-C-W31-5-O/P

Presentation: 8min,
Discussion: 3min

Tanapat Palaga

Department of Microbiology, Faculty of Science, Notch Signaling Regulates Macrophages Activation by LPS in the Presence of Immune
Chulalongkorn University, Bangkok, Thailand
ComplexDec. 14(Thu.), 201714:25-15:45

Room C

Dendritic cells andTsuneyasu
Macrophages-3: Inflammatory
KaishoResponses

Rikinari
Hanayama

100034 2-B-W20-1-O/P

Presentation: 7min,
Discussion: 3min

Sumie Hiramatsu

Department of Nephrology, Rheumatology,
Endocrinology and Metabolism, Okayama
University Graduate School of Medicine,
Dentistry and Pharmaceutical Sciences,
Okayama, Japan.

Dec. 13
14:25-15:45(Wed.), 2017

Room B

Systemic autoimmune
disease (1)100035 2-I-W25-7-P

Poster Presentation

Yo Ueda<strong>Inhibition of the mTOR Pathway and Glutaminolysis Facilitates the Expansion of
Department of Rheumatology and Clinicalimmunology, Kobe University Graduate School of Myeloid-Derived Suppressor Cells and Synergistically Ameliorates Arthritis in SKG
Medicine, Kobe, Japan
Mice</strong>

Dec. 13
16:00-17:00(Wed.), 2017

Exhibition Dendritic cells andMacrophages-1: OrganHall
specific Immune Tolerance

100036 3-G-W39-7-O/P

Presentation: 7min,
Discussion: 4min

Harumi Shirai

Department of Allergy and Rheumatology,
Graduate School of Medicine, The University ofTokyo, Tokyo, Japan

Investigation of pathogenesis of Adult onset Still&rsquo;s disease through lymphocyte
subsets analysis in peripheral blood followed by RNA-sequencing

Dec. 14(Thu.), 201714:25-15:45

Room G

100037 1-C-W6-4-O/P

Presentation: 7min,
Discussion: 3min

Kojiro Sato

Department of Rheumatology and Applied
Immunology, Saitama Medical University,
Saitama, Japan

Analysis of the function of Nfatc1 isoforms in the differentiation of osteoclasts and an
attempt to make short-form specific Nfatc1 knockout mice with the CRISPR/Cas9 system

Dec. 12(Tue.), 201714:55-16:15

100038 3-D-W32-9-O/P

Presentation: 7min,
Discussion: 3min

Takuto Nosaka

Second Department of Internal Medicine, Faculty<strong>Alveolar macrophages drive hepatocellular carcinoma lung metastasis inof Medical Sciences, Fukui University, Eiheijicollaboration with interstitial macrophages</strong>
machi, Japan

Dec. 14(Thu.), 201712:50-14:10

100039 2-C-W21-11-P

Poster Presentation

Rong Zhang

Division of Cancer Immunotherapy, Exploratory
Oncology Research &amp; Clinical Trial Center,
National Cancer Center, Kashiwa, Japan

Type 1 IFN-producing myeloid cells influence on host immune system to inhibit tumor
growthDec. 13
16:00-17:00(Wed.), 2017

Exhibition
Cell therapy
Hall100040 1-B-W4-1-O/P

Presentation: 7min,
Discussion: 2min

Ayako
Wakabayashi

Department of Microbiology and Immunology,
Nippon Medical School, Tokyo, Japan

Enhancement of epithelial cell death, cytoplasmic HMGB1 expression in IECs, and increaseof HMGB1 release by oral CT-stimulation

Dec. 12(Tue.), 201714:55-16:15

Room B

100041 1-A-W1-3-O/P

Presentation: 7min,
Discussion: 3min

Satoko TaharaHanaoka

Department of Immunology, Faculty of Medicine, Inhibition of house dust mite-induced Th2 responses by Allergin-1 immunoreceptor on
University of Tsukuba, Tsukuba, Japandendritic cells

Dec. 12(Tue.), 201713:20-14:40

100042 1-I-W18-1-O/P

Presentation: 7min,
Discussion: 3min

Soh Yamazaki

Department of Biochemistry, Toho University
School of Medicine

The AP-1 transcription factor JunB is essential for development of Th17 cells

Dec. 12(Tue.), 2017

100043 3-E-W34-8-O/P

Presentation: 7min,
Discussion: 3min

Tsubasa Okano

Department of Pediatrics and Developmental
Biology, Graduate School of Medical and Dental
Sciences, Tokyo Medical and Dental University(TMDU), Tokyo, Japan

100044 1-F-W11-3-O/P

Presentation: 9min,
Discussion: 2min

Naoto Nishii

100045 1-H-W16-11-P

Poster Presentation

100046 1-E-W9-17-P

Dec. 13
16:00-17:00(Wed.), 2017

Exhibition
Cell therapy
Hall
Room A

Tolerance and immune
suppression -2

Hitoshi
Kohsaka

Shinsuke
YasudaSatoshi Ishido

Kenichi Asano

Systemic autoimmune
disease (3)KimitoKawahata

ShingoNakayamada

Room C

Tissue-specific immune
diseases II

NaozumiIshimaru

Hiroto Tsuboi

Room D

Tumor immunology-1 (Tumor
antigens, antigen presenting
cells, anti-tumor T cells)

YutakaKawakami

Hirokazu
Matsushita

Hiroaki Ikeda

Koji Tamada

Endogenous innate immunity
and inflammation-2

Osamu
Takeuchi

SachikoTakamura(Akashi)Room A

Allergy-1 : Lower airway
allergic inflammation

Kenji Izuhara

Koubun Yasuda

14:55-16:15

Room I

Helper T cells

Masakatsu
YAMASHITA

Motoko Y.
KIMURA

Maternal B cells, engrafted in patients with X-linked severe combined immunodeficiency (XDec. 14
SCID), could undergo class switch recombination without somatic hypermutation and cause(Thu.), 2017
IgG1 gammopathy.

12:50-14:10

Room EB cell development andfunction

Yoshiteru
Sasaki

Reiko Shinkura

Department of Molecular Immunology, Graduate Systemic administration of low dose TLR7 agonist augments antitumor responses in the
School, Tokyo Medical and Dental University
PD-1 checkpoint blockade-resistant and regulatory T cell-dominant murine tumor models

Dec. 12(Tue.), 201713:20-14:40

Room F

Combination cancer
Hiroyoshi
immunothrapy -beyond
immune checkpoint inhibitors- Nishikawa

Yoshihiro
Hayakawa

Izumi Sasaki

Department of Immunology, Institute ofAdvanced Medicine, Wakayama Medical
University, Wakayama, Japan

Roles of arginine and methionine metabolism in cholera toxin-induced adjuvant effects

Dec. 12(Tue.), 2017

Odd Number / 16:30-17:30, Exhibition
Takayuki
Cytokines and chemokines-2
Even Number / 17:30-18:30 Hall
YoshimotoTakashi
Kobayashi

Poster Presentation

Kazuhiro Negoro

Department of Immunology, Institute ofAdvanced Medicine, Wakayama Medical
University, Wakayama, Japan

An Ets family member, Ets2 is required for Cholera toxin-induced arginase-1 gene
expression

Dec. 12(Tue.), 2017

Odd Number / 16:30-17:30, Exhibition Immune response to bacteial
Goro Matsuzaki Yuki Kinjo
infections
Even Number / 17:30-18:30 Hall

100047 3-B-W29-4-O/P

Presentation: 11min,
Discussion: 2min

Takanori So

Department of Microbiology and Immunology,
Early activation of group 2 innate lymphoid cells in the lung is critically controlled by the
Tohoku University Graduate School of Medicine,
TNFR superfamily molecule GITR
Sendai, Japan

Dec. 14(Thu.), 201714:25-15:45

100049 3-I-W42-8-P

Poster Presentation

Kaoru Toshima

Division of Glycopathology, Institute of Molecular
Biomembrane and Glycobiology, Tohoku Medical Sphingomyelin is involved in TCR-induced apoptosis in thymocyte development
and Pharmaceutical University, Miyagi, Japan

Dec. 14(Thu.), 2017

Odd Number / 16:00-17:00, Exhibition
T cell-2 : T cell signaling
Even Number / 17:00-18:00 Hall

100050 2-G-W23-1-O/P

Presentation: 10min,
Discussion: 3min

Kazuhiko
Yamamura

Department of Dermatology, Graduate School of
The transcription factor EPAS1 links DOCK8 deficiency to atopic skin inflammation via IL-31
Medical Sciences, Kyushu University, Fukuoka,
inductionJapan

Dec. 13
14:25-15:45(Wed.), 2017

100051 3-I-W43-9-P

Poster Presentation

Ryoyo Ikebuchi

Laboratory of Immunology, Faculty of Pharmacy,
Single-cell gene and protein expression analysis revealed functional and migratory
Osaka Ohtani University, Tondabayashi, Osaka,heterogeneity in regulatory T cells of inflamed skinJapan

Dec. 14(Thu.), 2017

DNA Methylation-dependent regulation of Cathepsin E gene expression by the transcription
factor Kaiso in MRL/lpr mice.

2 / 30

Room B

Room G

Innate Lymphocyte-2(ILC1,2,3)

Allergy-3 : Allergic dermatitis,
food allergy and allergic
conjunctivitis

Odd Number / 16:00-17:00, Exhibition
T cell-3 : T cell function
Even Number / 17:00-18:00 Hall

SusumuNAKAE

Shinichiro
SAWA

SatoshiMatsudaTadashiYokosuka

Kenji Izuhara

Tomohiro
YoshimotoHarumi Suzuki Ei Wakamatsu

The 46th Annual Meeting of The Japanese Society for Immunology
Submission ID

Program No.

Oral Presentation Time

Submission ID order

1st Author

Affiliation

Title

Date

Time

Venue

Session Title

Chair1Chair2100052 3-F-W36-9-O/P

Presentation: 7min,
Discussion: 3min

Masaaki
HASHIGUCHI

Department of Immunology, Dokkyo Medical
University School of Medicine, Mibu, Tochigi,
Japan

100053 1-D-W8-1-O/P

Presentation: 6min,
Discussion: 2.5min

Takayuki Chikata

Center for AIDS Research, Kumamoto
University, Kumamoto, Japan

100054 1-C-W5-10-P

Poster Presentation

Koji Shinoda

Department of Neurology, Neurological Institute,
A distinct repertoire of the &gamma;&delta; T cell population is associated with disease
Graduate School of Medical Sciences, Kyushu
severity of multiple sclerosis
University, Fukuoka, Japan

Dec. 12(Tue.), 2017

Odd Number / 16:30-17:30, Exhibition Tissue-specific immune
diseases I
Even Number / 17:30-18:30 Hall

100055 3-D-W33-5-O/P

Presentation: 7min,
Discussion: 3min

Chie Kudo-Saito<strong>Targeting the pathogenic mesenchymal stromal/stem cells prevents immune
Department of Immune Medicine, National
Cancer Center Research Institute, Tokyo, Japan exhaustion</strong>

Dec. 14(Thu.), 201714:25-15:45

Tumor immunology-2(Immunosuppression andmodulation in tumor
immunity)Toshihiko
Torigoe

Yoshihiro
Hayakawa

100056 1-A-W2-1-P

Poster Presentation

Oji Nakamura

Department of Applied Biological Chemistry,
Tokyo University of Agriculture and Technology,
Tokyo, Japan

Dec. 12(Tue.), 2017

Odd Number / 16:30-17:30, Exhibition Allergy-2: Upper airway
allergic inflammation andEven Number / 17:30-18:30 Hall
allergic responses

Tomohiro
YoshimotoRyoji Yagi

100057 3-B-W28-10-P

Poster Presentation

Masato Kamei

Department of Immunology, Juntendo University
MAIT cells exacerbate the disease course of oxazolone colitis.
School of Medicine, Tokyo, Japan

Dec. 14(Thu.), 2017

Odd Number / 16:00-17:00, Exhibition Innate Lymphocyte-1 (NKT,
MAIT, gdT, NK)
Even Number / 17:00-18:00 Hall

Kensuke
ShibataKazuyaIWABUCHI

100058 2-G-W23-2-O/P

Presentation: 10min,
Discussion: 3min

Akihiko Murata

Division of Immunology, Department of
Molecular and Cellular Biology, School of Life
Science, Faculty of Medicine, Tottori University,
Japan

Local skin memory response in contact dermatitis involves tissue resident memory T cells

Dec. 13
14:25-15:45(Wed.), 2017

Room G

Allergy-3 : Allergic dermatitis,
food allergy and allergic
conjunctivitis

Kenji Izuhara

Tomohiro
Yoshimoto

100059 3-I-W43-5-O/P

Presentation: 7min,
Discussion: 3min

Akihiro Shimba

Institute for Frontier Life and Medical Sciences,
Kyoto University, Kyoto, Japan

Glucocorticoids drive diurnal changes in distibution and response of T cells via IL-7 receptor
expression

Dec. 14(Thu.), 201714:25-15:45

Room IT cell-3 : T cell function

Harumi Suzuki Ei Wakamatsu

100060 3-B-W28-11-O/P

Presentation: 11min,
Discussion: 2min

Goh Murayama

Department of Immunology, Juntendo University
Role of mucosal-associated invariant T cells in lupus pathogenesis
School of Medicine, Tokyo, Japan

Dec. 14(Thu.), 201712:50-14:10

Room B

Innate Lymphocyte-1 (NKT,
MAIT, gdT, NK)

Kensuke
ShibataKazuyaIWABUCHI

100061 1-H-W15-6-O/P

Presentation: 6min,
Discussion: 2min

Masaaki Kawano

Department of Allergy and Immunology, Facultyof Medicine, Saitama Medical University,
Saitama, Japan<strong>Dopamine fluctuates cytokine secretion in innate and adaptive immune
responses</strong>

Dec. 12(Tue.), 201713:20-14:40

Room H

Cytokines and chemokines-1

Masaaki
Murakami

Akihiro Kimura

100062 2-F-W22-1-O/P

Presentation: 8min,
Discussion: 3min

Yoichi Sutoh

Iwate Tohoku Medical Megabank Organization,
Iwate Medical University, Yahaba, Japan<strong>Origin of thymic selection inferred from the deviated antigen receptor usage inlamprey</strong>

Dec. 13
14:25-15:45(Wed.), 2017

Room FT cell-1: T cell development
and repertoire selection

TaishinAkiyamaTakeshi Nitta

100063 1-I-W18-17-P

Poster Presentation

Shunta Kaneko

The RORgt-CCR6-CCL20 axis enhances Th17 cells invasion into the synovia of patients in
Department of Internal Medicine, Faculty of
Medicine, University of Tsukuba, Ibaraki, Japan. rheumatoid arthritis

Dec. 12(Tue.), 2017

Odd Number / 16:30-17:30, Exhibition
Helper T cells
Even Number / 17:30-18:30 Hall

Masakatsu
YAMASHITA

Motoko Y.
KIMURA

100064 1-A-W2-2-P

Poster Presentation

Inoue Akiko

Department of Otorhinolaryngology, Toho
University School of Medicine, Tokyo, Japan

Study of relationship of allergy and chronic rhinosinusitis

Dec. 12(Tue.), 2017

Odd Number / 16:30-17:30, Exhibition Allergy-2: Upper airway
allergic inflammation andEven Number / 17:30-18:30 Hall
allergic responses

Tomohiro
YoshimotoRyoji Yagi

100065 2-I-W25-5-O/P

Presentation: 7min,
Discussion: 3min

Sho Sendo

Department of Rheumatology and Clinical
Immunology, Kobe University Graduate Schoolof Medicine, Kobe, Japan.

<strong>CD11b<sup>+</sup>Gr1<sup>dim</sup> Tolerogenic Dendritic Cell-like Cells
Dec. 13Differentiated from Monocytic-MDSCs Suppress the Progression of Interstitial Lung Disease(Wed.), 2017
in SKG Mice</strong>

14:25-15:45

Room I

Dendritic cells andMacrophages-1: Organspecific Immune Tolerance

Satoshi Ishido

Kenichi Asano

100066 1-D-W7-9-O/P

Presentation: 6min,
Discussion: 2min

Tomoko Takahashi School of Science, The University of Tokyo

Department of Biological Sciences, Graduate

LGP2 upregulates apoptosis-related genes by acting as an RNA silencing modulator during
viral infection

Dec. 12(Tue.), 201713:20-14:40

Room D

Virus infection-1

Taro Kawai

Mitsutoshi
Yoneyama

100067 2-A-W19-17-O/P

Presentation: 7min,
Discussion: 3min

Chiao-Ching Hsu

Laboratory of Immune Regulation, Graduate
School of Medicine, Osaka University, Japan<strong>Human LYPD8 protein has motility inhibitory functions to pathogenic flagellated
bacteria</strong>

Dec. 13
14:25-15:45(Wed.), 2017

Room A

Mucosal-Skin Immunity-1

Kenji
Kabashima

Yoshiyuki Goto

100068 2-B-W20-11-P

Poster Presentation

Chi Liu

Division of Transplantation Immunology, National<strong>Combination of 5-aminolevulinic acid and iron prevents skin fibrosis in murine
Center for Child Health and Development, Tokyo,
sclerodermatous grafts-versus-host disease</strong>Japan

Dec. 13
16:00-17:00(Wed.), 2017

Exhibition Systemic autoimmune
disease (1)Hall

Hitoshi
Kohsaka

Shinsuke
Yasuda100070 1-B-W3-2-O/P

Presentation: 7min,
Discussion: 2min

SachikoC4b binding protein negatively regulates cell-surface TLRs response

Dec. 12(Tue.), 201713:20-14:40

Room B

100071 3-G-W39-2-P

Poster Presentation

Shizuyo Tsujimura School of Medicine University of Occupational
and Environmental Health, Kitakyushu, Japan<strong>The Characteristic of the P glycoprotein expression on the B cell subsets inrheumatoid arthritis</strong>

Dec. 14(Thu.), 2017

Odd Number / 16:00-17:00, Exhibition Systemic autoimmune
disease (3)Even Number / 17:00-18:00 Hall

100072 2-B-W20-14-P

Poster Presentation

Mareki Ohtsuji

Toin Human Science and Technology Center,
Department of Biomedical Engineering, Toin
University of Yokohama,Kanagawa,Japan<strong>Inhibitory effect of the blocking of monocyte recruitment from the blood on
spontaneously occurring arthritis </strong><strong>in arthritis-prone Fc&gamma;RIIBdeficient mice</strong>

Dec. 13
16:00-17:00(Wed.), 2017

Exhibition Systemic autoimmune
disease (1)Hall100073 2-G-W23-17-P

Poster Presentation

Kazunobu OKON

Department of Applied Biological Chemistry,
Tokyo University of Agriculture and Technology

Studies of the anti-allergic activity of honeybush

Dec. 13
16:00-17:00(Wed.), 2017

Exhibition Allergy-3 : Allergic dermatitis,
food allergy and allergic
Kenji IzuharaHallconjunctivitis

100074 3-I-W43-6-P

Poster Presentation

Guangwei Cui

Laboratory of Immune Regulation, Institute for
Frontier Life and Medical Sciences, Kyoto
University, Kyoto, Japan

Competition between STAT5 and PI3K of the IL-7R modulates T cell and type 2 ILC
development in vivo

Dec. 14(Thu.), 2017

Akashi- Aichi Medical University School of Medicine,

Takamura

Nagakute, JapanThe First Department of Internal Medicine,

Tumor necrosis factor superfamily member (TNFSF) 13, APRIL and TNFSF13B, BAFF
downregulate homeostatic immunoglobulin production in intestines

Dec. 14(Thu.), 201712:50-14:10

Room F

Mucosal-Skin Immunity-2

Koji Hase

Gyohei Egawa

Control of HIV-1 by an HLA-B*52:01-HLA-C*12:02 protective haplotype

Dec. 12(Tue.), 201714:55-16:15

Room D

Virus infection-2

Takashi Fujita

HiroyukiOshiumiMitsuru
Matsumoto

Daisuke
Kamimura

Effect of honeybush extracts on the murine model of pollen allergy

3 / 30

Room D

Endogenous innate immunity
and inflammation-1

Odd Number / 16:00-17:00, Exhibition
T cell-3 : T cell function
Even Number / 17:00-18:00 Hall

Tatsuya Saitoh Takuya Uehata
KimitoKawahata

ShingoNakayamada

Hitoshi
Kohsaka

Shinsuke
YasudaTomohiro
YoshimotoHarumi Suzuki Ei Wakamatsu

The 46th Annual Meeting of The Japanese Society for Immunology
Submission ID

Program No.

Oral Presentation Time

Submission ID order

1st Author

Affiliation

Title

Date

Time

Venue

Session Title

Room B

Innate Lymphocyte-1 (NKT,
MAIT, gdT, NK)

Chair1Chair2100075 3-B-W28-2-O/P

Presentation: 11min,
Discussion: 2min

Tsukasa NabekuraLife Science Center, Tsukuba Advanced
Research Alliance, University of Tsukuba,
Ibaraki, Japan

100076 3-A-W26-11-P

Poster Presentation

Cuiying He

Department of Immunology and Parasitology,
University of Occupational and Environmental
Health, Kitakyushu, Japan.

<strong>Urban particulate matter 2.5 induced immunosuppression in splenocytes is relatedwith lipopolysaccharide level on particulate matter 2.5</strong>

Dec. 14(Thu.), 2017

Odd Number / 16:00-17:00, Exhibition Tolerance and immune
suppression -1
Even Number / 17:00-18:00 Hall

100077 1-B-W4-14-P

Poster Presentation

Takashi Mino

Institute for Frontier Life and Medical Sciences,
Kyoto University<strong>Regnase-1 regulates inflammatory mRNAs during pioneer rounds oftranslation</strong>

Dec. 12(Tue.), 2017

Odd Number / 16:30-17:30, Exhibition Endogenous innate immunity Osamu
and inflammation-2
Even Number / 17:30-18:30 Hall
Takeuchi

100078 1-B-W3-8-O/P

Presentation: 7min,
Discussion: 2min

Masahiro Nagata

Department of Molecular Immunology, Research
Intracellular metabolite, &beta;-glucosylceramide, is an endogenous adjuvant acting throughInstitute for Microbial Diseases, Osaka
MincleUniversity, Osaka, Japan

Dec. 12(Tue.), 201713:20-14:40

100079 1-E-W9-14-P

Poster Presentation

Hideo Negishi

Department of Molecular Immunology, Instituteof Industrial Science, The University of Tokyo,
Tokyo, Japan

Identification and analysis of commensal bacteriophage in the intestine

Dec. 12(Tue.), 2017

Odd Number / 16:30-17:30, Exhibition Immune response to bacteial
Goro Matsuzaki Yuki Kinjo
infections
Even Number / 17:30-18:30 Hall

100080 1-E-W9-2-O/P

Presentation: 7min,
Discussion: 3min

Imai Takashi

Division of Molecular Immunology, Medical
Institute of Bioregulation, Kyushu University,
Fukuoka, Japan<strong>Glycolipids in group A <em>Streptococcus </em>are recognized by Mincle totrigger host immune responses</strong>

Dec. 12(Tue.), 201713:20-14:40

Room E

Immune response to bacteial
infections

Goro Matsuzaki Yuki Kinjo

100081 2-G-W23-16-O/P

Presentation: 10min,
Discussion: 3min

MAYUMI UETA

Departments of Frontier Medical Science andDifference in the tear cytokines between chronic Stevens-Johnson syndrome patients andTechnology for Ophthalmology, Kyoto Prefectural
Atopic keratoconjunctivitis
University of Medicine, Kyoto, Japan

Dec. 13
14:25-15:45(Wed.), 2017

Room G

Allergy-3 : Allergic dermatitis,
food allergy and allergic
conjunctivitis

Kenji Izuhara

Tomohiro
Yoshimoto100082 1-I-W18-2-O/P

Presentation: 7min,
Discussion: 3min

SHINYA TANAKA

Research Institute for Biomedical Sciences,
Tokyo University of Science, Chiba, Japan<strong>Tripartite motif-containing 33 (Trim33) mediates a pro-inflammatory phenotype ofTh17 cells.</strong>

Dec. 12(Tue.), 201714:55-16:15

Room I

Helper T cells

Masakatsu
YAMASHITA

Motoko Y.
KIMURA

100083 3-G-W39-1-P

Poster Presentation

Tatsuhiko Ozawa

Department of Immunology, Graduate School of
Evolution of anti-citrullinated peptide antibody (ACPA): analysis of autoantigen under native
Medicine and Pharmaceutical Sciences,condition using a human monoclonal ACPA
University of Toyama, Toyama, Japan

Dec. 14(Thu.), 2017

Odd Number / 16:00-17:00, Exhibition Systemic autoimmune
disease (3)Even Number / 17:00-18:00 Hall

KimitoKawahata

ShingoNakayamada

100084 3-G-W39-8-O/P

Presentation: 7min,
Discussion: 4min

Noriko Arase

Department of Immunochemistry, Research
Recognition of SS-A/IgG/HLA-DR complex by autoantibodies in Sjogren&rsquo;s syndrome
Institute for Microbial Diseases, Osaka University

Dec. 14(Thu.), 201714:25-15:45

Systemic autoimmune
disease (3)KimitoKawahata

ShingoNakayamada

100085 2-A-W19-15-P

Poster Presentation

Kazuaki Nakata

College of Bioresource Sciences, Nihon
University, Kanagawa, Japan

Kenji
Kabashima

Yoshiyuki Goto

100086 3-F-W37-8-P

Poster Presentation

Tomomi
HashizumeTakizawa

Nihon University School of Dentistry at Matsudo,
recombinant <em>Salmonella</em>-derived antigen-specific intestinal IgA antibody
Chiba, Japan

Eiji Umemoto

Jun Kunisawa

Toshihiko
Torigoe

Kenichiro Seino

Masakatsu
YAMASHITA

Motoko Y.
KIMURA

Tracking the fate of antigen-specific versus cytokine-activated natural killer cells after
cytomegalovirus infection

Dec. 14(Thu.), 201712:50-14:10

miR-21-5p regulates intestinal epithelial permeability through ADP-ribosylation factor 4(ARF4)

Dec. 13
16:00-17:00(Wed.), 2017

Surface IgA<sup>+</sup> Peyer&rsquo;s patch B cells play key roles for induction of

Dec. 14(Thu.), 2017

responses

Room G

Endogenous innate immunity
and inflammation-1

Exhibition
Mucosal-Skin Immunity-1
Hall

Odd Number / 16:00-17:00, Exhibition
Mucosal-Skin Immunity-3
Even Number / 17:00-18:00 Hall

KazuyaIWABUCHI

Taku Okazaki

Shunsuke
Chikuma
SachikoTakamura(Akashi)

Tatsuya Saitoh Takuya Uehata

100087 1-F-W12-2-O/P

Presentation: 10min,
Discussion: 3min

Harada Michishige (IMS)

100088 1-I-W18-16-P

Poster Presentation

Izumi Kurata

Division of Rheumatology, Department of
The Role of Follicular Helper 17 T cells and Desialylation of Autoantibody in Glucose-6Internal Medicine, Faculty of Medicine, University
phosphate Isomerase Induced Arthritis
of Tsukuba, Tsukuba, Japan

Dec. 12(Tue.), 2017

Odd Number / 16:30-17:30, Exhibition
Helper T cells
Even Number / 17:30-18:30 Hall

100089 3-E-W34-7-O/P

Presentation: 7min,
Discussion: 3min

Mineto Ota

The Department of Allergy and Rheumatology,
Graduate School of Medicine, The University ofTokyo, Tokyo, Japan

Abnormal B cell receptor repertoire maturation in SLE unveiled by RNA sequencing of
immune cells

Dec. 14(Thu.), 201712:50-14:10

Room EB cell development andfunction

Yoshiteru
Sasaki

Reiko Shinkura

100090 2-A-W19-11-O/P

Presentation: 7min,
Discussion: 3min

Tomohiro FUKAYA Infectious Diseases, Faculty of Medicine,

Critical role of IL-22 binding protein in the control of skin inflammation

Dec. 13
14:25-15:45(Wed.), 2017

Room A

Mucosal-Skin Immunity-1

Kenji
Kabashima

Yoshiyuki Goto

100091 2-F-W22-7-O/P

Presentation: 8min,
Discussion: 3min

Kenta Kondo

Institute of Advanced Medical Sciences,
University of Tokushima, Tokushima, Japan.

Thymoproteasome-dependent positive selection conditions <em>in vivo</em> immune
responses in CD8<sup>+</sup> T cells

Dec. 13
14:25-15:45(Wed.), 2017

Room FT cell-1: T cell development
and repertoire selection

TaishinAkiyamaTakeshi Nitta

100092 2-B-W20-15-P

Poster Presentation

Nobuhito
NEMOTO

Department of immunology, Yamagata
University, Yamagata, Japan

Integrated analysis of intestinal immunity at initial onset and relapse stages in arthritis mouse Dec. 13
model(Wed.), 2017

Hitoshi
Kohsaka

Shinsuke
Yasuda100093 1-E-W9-18-P

Poster Presentation

Masanori Iseki

Department of Immunology and Molecular
Genetics, Kawasaki Medical School, Kurashiki,Japan

BST-1/CD157 on B cells negatively regulates Toll-like receptor signaling

100094 2-I-W25-3-O/P

Presentation: 7min,
Discussion: 3min

Hisako Kayama

Graduate School of Medicine, Osaka University, Spi-C inhibits expression of a subset of Toll-like receptor 4-inducible genes in intestinal
Suita, Japan
CX<sub>3</sub>CR1<sup>high</sup> macrophages and prevents colonic inflammation

100095 1-B-W3-14-P

Poster Presentation

Shimpei Watanabe Ltd., Tokyo, Japan

100096 2-B-W20-6-O/P

Presentation: 7min,
Discussion: 3min

Sonia Zeggar

RIKEN Center for Integrative Medical Science

CD81 is associated with non-apoptotic cell death in B cell lymphoma cell lines through HLA- Dec. 12
DR&alpha;/&beta; engagement(Tue.), 2017

Room B

Kensuke
Shibata

Division of Immunology, Department of
University of Miyazaki

R&amp;D Innovation Group, Kracie Holdings,

Arctigenin suppresses the activation of NLRP3 and AIM2 inflammasomes.

Department ofNephrology,Rheumatology,Endocrinology andLgals9 deficiency attenuates nephritis and arthritis in pristane induced mice model of SLE
Metabolism,Okayama University graduate schoolof medecine,Okayama,Japan

4 / 30Dec. 12(Tue.), 201714:55-16:15

16:00-17:00

Immune responses in cacer
immunotherapy

Exhibition Systemic autoimmune
disease (1)Hall

Odd Number / 16:30-17:30, Exhibition Immune response to bacteial
Goro Matsuzaki Yuki Kinjo
infections
Even Number / 17:30-18:30 Hall

Dec. 13
14:25-15:45(Wed.), 2017
Dec. 12(Tue.), 2017

Room F

Room I

Dendritic cells andMacrophages-1: Organspecific Immune Tolerance

Satoshi Ishido

Kenichi Asano

Odd Number / 16:30-17:30, Exhibition Endogenous innate immunity
Tatsuya Saitoh Takuya Uehata
and inflammation-1
Even Number / 17:30-18:30 Hall

Dec. 13
14:25-15:45(Wed.), 2017

Room B

Systemic autoimmune
disease (1)Hitoshi
Kohsaka

Shinsuke
Yasuda

The 46th Annual Meeting of The Japanese Society for Immunology
Submission ID

Program No.

Oral Presentation Time

1st Author

Submission ID orderAffiliation

Title

Date

Time

Venue

Session Title

Room G

Hematopoiesis and immune
environments

Chair1Chair2

SIRP&alpha;<sup>+</sup> dendritic cells regulate homeostasis of fibroblastic reticular cells
via TNF receptor ligands in the adult spleenDec. 12(Tue.), 201713:20-14:40

TakashiNagasawa

HitoshiTakizawa<strong>Suppression of murine tumor growth through CD8+ CTLs via activated DEC-205+
dendritic cells by sequential administration of &alpha;-galactosylceramide in vivo: A possible
mechanism for SSM (Maruyama Vaccine)</strong>

Dec. 14(Thu.), 2017

Odd Number / 16:00-17:00, Exhibition Tumor immunology-1 (Tumor Yutaka
antigens, antigen presenting
Even Number / 17:00-18:00 Hall
Kawakami
cells, anti-tumor T cells)

Hirokazu
Matsushita

NaozumiIshimaru

Hiroto Tsuboi

100097 1-G-W13-16-O/P

Presentation: 6min,
Discussion: 2min

Yasuyuki Saito

Division of Molecular and Cellular Signaling,
Department of Biochemistry and Molecular
Biology, Kobe University Graduate School of
Medicine, Kobe, Japan

100098 3-D-W32-12-P

Poster Presentation

Hidemi Takahashi

Department of Microbiology and Immunology,
Nippon Medical School, Tokyo, Japan

100099 1-C-W6-3-P

Poster Presentation

Masato Kinoshita

Dendritic cell-specific ablation of the protein tyrosine phosphatase Shp-1 induces
Department of Nephrology and Rheumatology,
Gunma University Graduate School of Medicine, autoimmune sialadenitis characterized by infiltration of CD4<sup>+</sup> T cells and B
Gunma, Japan
cells

Dec. 12(Tue.), 2017

Odd Number / 16:30-17:30, Exhibition Tissue-specific immune
diseases II
Even Number / 17:30-18:30 Hall

100100 1-A-W1-4-O/P

Presentation: 7min,
Discussion: 3min

Koji Hayashizaki

Department of Immunology, Graduate School of Myosin light chains 9 and 12 are functional ligands for CD69 that regulate airway
Medicine, Chiba University, Chiba, Japaninflammation

Dec. 12(Tue.), 201713:20-14:40

Room A

Allergy-1 : Lower airway
allergic inflammation

Kenji Izuhara

Koubun Yasuda

100101 2-F-W22-5-O/P

Presentation: 8min,
Discussion: 3min

Satoshi Kojo

Lab. for Transcriptional Regulation, RIKEN IMS, Regulation of Runx3 activity in immune system development by the C-terminal end amino
Yokohama, Japanacid sequence

Dec. 13
14:25-15:45(Wed.), 2017

Room FT cell-1: T cell development
and repertoire selection

TaishinAkiyamaTakeshi Nitta

100102 1-D-W7-5-O/P

Presentation: 6min,
Discussion: 2min

Tatsuya Yamazaki Aichi Medical University, School of Medicine<strong>Neutralizing anti-hemagglutinin IgG and IgA mAb induced by gene-basehydrodynamic injection have a therapeutic effect in<u> upper respiratory influenza virus
infection</u></strong>

Dec. 12(Tue.), 201713:20-14:40

Room D

Virus infection-1

Taro Kawai

Mitsutoshi
Yoneyama

100103 3-E-W34-1-O/P

Presentation: 7min,
Discussion: 3min

Sachiko Hirose

Toin Human Science and Technology Center,
Department of Biomedical Engineering, Toin
University of Yokohama, Yokohama, Japan<strong>Independent effect of inhibitory </strong><strong>IgG Fc receptor</strong><strong>IIB on</strong><strong> B cells and monocytes </strong><strong>on<em>Yaa</em>-induced murine lupus</strong>

Dec. 14(Thu.), 201712:50-14:10

Room EB cell development andfunction

Yoshiteru
Sasaki

Reiko Shinkura

100104 1-H-W16-9-O/P

Presentation: 6min,
Discussion: 2min

Kazuko Uno

Louis Pasteur Center for Medical Research

Using non-negative matrix factorization analysis of IFN/Cytokine production and those ofserum levels to identify groups at high-risk of disease or those in the early stages of disease

Dec. 12(Tue.), 201714:55-16:15

Room H

Cytokines and chemokines-2

Takayuki
YoshimotoTakashi
Kobayashi

100105 1-H-W16-12-P

Poster Presentation

Toshikazu Kondo

Department of Forensic Medicine, Wakayama
Medical University, Wakayama, JapanThe absence of CCL3 exaggerates CaCl<sub>2</sub>-induced aortic aneurysm

Dec. 12(Tue.), 2017

Odd Number / 16:30-17:30, Exhibition
Takayuki
Cytokines and chemokines-2
Even Number / 17:30-18:30 Hall
YoshimotoTakashi
Kobayashi

100106 3-D-W32-8-P

Poster Presentation

Shinsuke Nakajima Cancer Research Institute, Kanazawa University, Caspase-1-induced pyroptosis potentiates anti-tumor immunity

Dec. 14(Thu.), 2017

Odd Number / 16:00-17:00, Exhibition Tumor immunology-1 (Tumor Yutaka
antigens, antigen presenting
Even Number / 17:00-18:00 Hall
Kawakami
cells, anti-tumor T cells)

Hirokazu
Matsushita

100107 1-H-W15-5-O/P

Presentation: 6min,
Discussion: 2min

Mizuho Nosaka

Department of Forensic Medicine, Wakayama
Medical University, Wakayama, Japan

Dec. 12(Tue.), 201713:20-14:40

100108 1-E-W9-7-P

Poster Presentation

Krisana Asano

Department of Microbiology and Immunology,<strong>Establishment of a mouse uterine infection model of <em>Staphylococcus aureus
Hirosaki University Graduate School of Medicine,</em>for studying a role of toxic shock syndrome toxin-1</strong>
Aomori, Japan

Dec. 12(Tue.), 2017

Odd Number / 16:30-17:30, Exhibition Immune response to bacteial
Goro Matsuzaki Yuki Kinjo
infections
Even Number / 17:30-18:30 Hall

100109 1-G-W13-4-O/P

Presentation: 6min,
Discussion: 2min

Takao Sudo

Department of Immunology and Cell Biology,
Osaka University Graduate School of Medicine,
Osaka, Japan

Dec. 12(Tue.), 201713:20-14:40

Room G

Hematopoiesis and immune
environments

TakashiNagasawa

HitoshiTakizawa

100110 1-A-W2-9-O/P

Presentation: 7min,
Discussion: 3min

Dat Nguyen-Tien

Division of Molecular Biology, Research Institute<strong>A selection technique for human IgE<sup>+</sup> memory B cells and thefor Biomedical Sciences, Tokyo University offunction of the &ldquo;new&rdquo; isoform of human IgE</strong>
ScienceDec. 12(Tue.), 201714:55-16:15

Room A

Allergy-2: Upper airway
allergic inflammation andallergic responses

Tomohiro
YoshimotoRyoji Yagi

100111 1-I-W17-8-P

Poster Presentation

Segawa Seiji

Department of Internal Medicine, Faculty of
Medicine, University of Tsukuba, Japan.

The analysis of placenta specific 8 in monocytes from Adult Still&rsquo;s disease

Dec. 12(Tue.), 2017

Odd Number / 16:30-17:30, Exhibition
Human Immunology
Even Number / 17:30-18:30 Hall

Koji Yasutomo Keishi Fujio

100112 3-I-W43-16-P

Poster Presentation

Ruka Setoguchi

RIKEN Center for Integrative Medical Sciences,
Kanagawa, Japan<strong>Impairment of memory CD8 T cell maintenance in MHC class II deficient mice iscaused by inflammation not by CD4 T cell deficiency</strong>

Dec. 14(Thu.), 2017

Odd Number / 16:00-17:00, Exhibition
T cell-3 : T cell function
Even Number / 17:00-18:00 Hall

Harumi Suzuki Ei Wakamatsu

100113 1-A-W2-10-O/P

Presentation: 7min,
Discussion: 3min

Mariana Almeida

Department of Immunology, Faculty of Medicine, Inhibition of house dust mite-induced MAP kinase activation in dendritic cells by Allergin-1
University of Tsukuba, Tsukuba, Japanimmunoreceptor

Dec. 12(Tue.), 201714:55-16:15

100114 3-D-W33-8-O/P

Presentation: 7min,
Discussion: 3min

Marija Mojic

Division of Pathogenic Biochemistry Institute of <strong>Tumor-specific CTL&#39;s reduced clonality and proliferation index, not the
Natural Medicine, University of Toyama, Toyama, inhibitory immune checkpoint expression, as hallmarks of B16 melanoma immuneJapanevasion</strong>

Dec. 14(Thu.), 201714:25-15:45

100115 1-H-W15-10-P

Poster Presentation

Takehiko Shibata

Department of Immunology, National Institute of
The role of RSV-induced Gas6/Axl signaling in secondary bacterial infection.
Infectious Diseases, Tokyo, Japan

Dec. 12(Tue.), 2017

Odd Number / 16:30-17:30, Exhibition
Masaaki
Cytokines and chemokines-1
Even Number / 17:30-18:30 Hall
Murakami

Akihiro Kimura

100116 1-D-W7-4-O/P

Presentation: 6min,
Discussion: 2min

Kayoko Sato

Influenza Virus Research Center, National
Institute of Infectious Diseases, Tokyo, Japan

Dec. 12(Tue.), 201713:20-14:40

Room D

Virus infection-1

Taro Kawai

Mitsutoshi
Yoneyama

100117 2-A-W19-8-O/P

Presentation: 7min,
Discussion: 3min

Takahiro Nagatake of Biomedical Innovation, Health and Nutrition

and ameliorated skin inflammation in DNFB-induced contact hypersensitivity modelDec. 13
14:25-15:45(Wed.), 2017

Room A

Mucosal-Skin Immunity-1

Kenji
Kabashima

Yoshiyuki Goto

Poster Presentation

Siddhika Pareek<strong>Comparative analysis of gut microbiome diversity between Japanese and Indiancohorts exhibits a diet-dependent synergism between bacteria and fungi</strong>

Dec. 13
16:00-17:00(Wed.), 2017

Exhibition
Mucosal-Skin Immunity-1
Hall

Kenji
Kabashima

Yoshiyuki Goto

Department of Microbiology and Immunology,

Division of Immunology and Molecular Biology,

100118 2-A-W19-2-P

Ishikawa, Japan

Absence of CCR5 axis exaggerates thrombus formation through reduced uPA, tPA and
VEGF expression in murine DVT mode

Stressed microenvironment induced by 5-FU promotes the proliferation of HSPC in bonemarrow

TLR agonists enhance avidity and ADCC activities of virus-specific antibodies upon abooster immunization of influenza vaccines

Laboratory of Vaccine Materials and Laboratoryof Gut Environmental System, National Institutes 17,18-EpETE, a metabolite of omega-3 essential fatty acids, inhibited neutrophil mobility(NIBIOHN), Osaka, Japan
Laboratory of Immune Regulation, Graduate
School of Medicine, Osaka University, Osaka,Japan

5 / 30

Room H

Cytokines and chemokines-1

Masaaki
Murakami

Akihiro Kimura

Room A

Allergy-2: Upper airway
allergic inflammation andallergic responses

Tomohiro
YoshimotoRyoji Yagi

Room D

Tumor immunology-2(Immunosuppression andmodulation in tumor
immunity)Toshihiko
Torigoe

Yoshihiro
Hayakawa

The 46th Annual Meeting of The Japanese Society for Immunology
Submission ID

Program No.

Oral Presentation Time

1st Author

Submission ID orderAffiliation

Title
The effects of <em>peptidylarginine deiminase 4</em> in imiquimod-induced lupus model
mice.

Date

100119 2-B-W20-9-O/P

Presentation: 7min,
Discussion: 3min

Norio Hanata

Department of Allergy and Rheumatology,
Graduate School of Medicine, The University ofTokyo, Tokyo, Japan

100120 3-H-W40-5-P

Poster Presentation

Kyosuke Inui

Department of Immunology, Graduate School of
Pharmaceutical Sciences, Hokkaido University, STAP-2 negatively controls Fc&epsilon;RI-mediated mast cell activation.
Hokkaido, Japan

Dec. 14(Thu.), 2017

100121 1-E-W10-13-P

Poster Presentation

Sonoko Tasaki

Section of Infection Biology, Department of
Investigation of mechanisms underlying the T cell response in oral candidasis.
Functional Biosciences, Fukuoka Dental College.

100122 3-H-W40-6-P

Poster Presentation

Kazumi Kasakura

100123 2-C-W21-5-P

Poster Presentation

100124 1-G-W13-15-P

Time

Session Title

Room B

Systemic autoimmune
disease (1)Chair1Chair2

Hitoshi
Kohsaka

Shinsuke
YasudaOdd Number / 16:00-17:00, Exhibition
Granulocyte & Mast cells
Even Number / 17:00-18:00 Hall

Atsuhito Nakao

YosukeKurashima

Dec. 12(Tue.), 2017

Odd Number / 16:30-17:30, Exhibition Immune response to
mycobacteial and fungal
Even Number / 17:30-18:30 Hall
infections

Kazuyoshi
Kawakami

Hiromitsu Hara

Department of Biological Science andTechnology, Tokyo University of Science, Tokyo, The effect of commensal bacteria on anaphylactic reaction
Japan

Dec. 14(Thu.), 2017

Odd Number / 16:00-17:00, Exhibition
Granulocyte & Mast cells
Even Number / 17:00-18:00 Hall

Atsuhito Nakao

YosukeKurashima

Shuhei Yonamine

Department of Dermatology, Graduate School of
Rapid isolation of tumor antigen specific antibodies from semi-synthetic alpaca VHH phage
Medicine, University of the Ryukyus, Nishihara,display library for cancer immunotherapy.
Okinawa, Japan.

Dec. 13
16:00-17:00(Wed.), 2017

Hiroaki Ikeda

Koji Tamada

Poster Presentation

Krutula NairRIKEN Center for Integrative Medical Sciences,
Yokohama, Japan

Dec. 12(Tue.), 2017

Odd Number / 16:30-17:30, Exhibition Hematopoiesis and immune
environments
Even Number / 17:30-18:30 Hall

TakashiNagasawa

HitoshiTakizawa

100125 3-F-W37-19-P

Poster Presentation

Naoto Yoshino

Division of Infectious Diseases and Immunology,
Department of Microbiology, School of Medicine, Mucosal adjuvanticity of surfactin correlates with the surface-active property
Iwate Medical University, Iwate, Japan

Dec. 14(Thu.), 2017

Odd Number / 16:00-17:00, Exhibition
Mucosal-Skin Immunity-3
Even Number / 17:00-18:00 Hall

Eiji Umemoto

Jun Kunisawa

100126 3-E-W35-2-O/P

Presentation: 7min,
Discussion: 3min

Mayuko Shimoda

Laboratory of Host Defense, Research Institutefor Microbial Diseases Osaka University, Suita,
Osaka, Japan

Dec. 14(Thu.), 201714:25-15:45

Room E

Germinal center reaction andplasma cells

Masaki Hikida

Wataru Ise

100127 3-G-W38-1-O/P

Presentation: 7min,
Discussion: 4min

Shigeru Iwata

The First Department of Internal Medicine,
reprograming in T</strong>
School of Medicine, University of Occupational&amp; Environmental Health, Japan, Kitakyushu,
Fukuoka, Japan<strong>helper 1
Dec. 14cells</strong><strong>and </strong><strong>its relevance to (Thu.), 2017 12:50-14:10
pathogenesis of SLE</strong>Room G

Systemic autoimmune
disease (2)Yoshiya Tanaka

Masayuki
Nishide100128 2-A-W19-16-O/P

Presentation: 7min,
Discussion: 3min

Yuki Usui

Division of Systems Immunology, Institute ofMedical Science, The University of Tokyo<strong>Maintenance of intestinal barrier function by long-term intake of LB81
yogurt</strong>

Dec. 13
14:25-15:45(Wed.), 2017

Room A

Mucosal-Skin Immunity-1

Kenji
Kabashima

Yoshiyuki Goto

100129 1-C-W5-7-O/P

Presentation: 7min,
Discussion: 3min

Satoshi Yamada

Department of Intelligent MechanicalEngineering, Okayama University of Science,
Okayama, Japan

Computer model of a gateway of immune cells across blood-brain barrier

Dec. 12(Tue.), 201713:20-14:40

Room C

Tissue-specific immune
diseases I

Mitsuru
Matsumoto

Daisuke
Kamimura

100130 3-A-W26-5-O/P

Presentation: 10min,
Discussion: 3min

Shigenori Nagai

Department of Molecular Immunology, Tokyo
Medical and Dental University, Tokyo, Japan

PI3K-Akt pathway enhances type 1 regulatory T cell differentiation induced by IL-27

Dec. 14(Thu.), 201712:50-14:10

Room A

Tolerance and immune
suppression -1

Taku Okazaki

Shunsuke
Chikuma

100131 2-B-W20-4-O/P

Presentation: 7min,
Discussion: 3min

Takamasa Cho

Division of Clinical Nephrology andRheumatology,Niigata University, Niigata,Japan

Anti-ribosomal-P antibody induces psychosis and hepatitis

Dec. 13
14:25-15:45(Wed.), 2017

Room B

Systemic autoimmune
disease (1)Hitoshi
Kohsaka

Shinsuke
Yasuda100132 3-G-W39-9-O/P

Presentation: 7min,
Discussion: 4min

Yoshinobu Koyama Rheumatology, Japan Red Cross Okayama

Exercise-induced pulmonary hypertension at early stage of systemic sclerosis: changes ingene expression of peripheral blood cells

Dec. 14(Thu.), 2017

Room G

Systemic autoimmune
disease (3)KimitoKawahata

ShingoNakayamada

100133 2-F-W22-12-P

Poster Presentation

Ryo Yokota

Quantification of inter-sample differences in repertoire of T cell receptors

Dec. 13
16:00-17:00(Wed.), 2017

Exhibition T cell-1: T cell development
and repertoire selection
Hall

TaishinAkiyamaTakeshi Nitta

100134 2-F-W22-10-O/P

Presentation: 8min,
Discussion: 3minKazumasa Kaneko of Tokyo, Tokyo, Japan

Graduate School of Engineering, The University

Mathematical modeling of thymic T cell development via interaction with thymic epithelialcells

Dec. 13
14:25-15:45(Wed.), 2017

Room FT cell-1: T cell development
and repertoire selection

TaishinAkiyamaTakeshi Nitta

100135 1-I-W18-5-P

Poster Presentation

Kyoko NISHIDA

Department of Immunology and Pathology,
National Center for Global Health and Medicine

NQO1 play a pathogenic role in autoimmune diseases through the suppression of IL-10
production in Th17 cells

Dec. 12(Tue.), 2017

Odd Number / 16:30-17:30, Exhibition
Helper T cells
Even Number / 17:30-18:30 Hall

Masakatsu
YAMASHITA

Motoko Y.
KIMURA

100136 1-E-W9-3-P

Poster Presentation

Yukiko Akahori

International University of Health and Welfare,
Narita, Japan

Dectin-1 mediates innate immune responses in <em>Streptococcus pneumoniae</em>
infection

Dec. 12(Tue.), 2017

Odd Number / 16:30-17:30, Exhibition Immune response to bacteial
Goro Matsuzaki Yuki Kinjo
infections
Even Number / 17:30-18:30 Hall

100137 1-E-W9-12-P

Poster Presentation

Shiho Suzuki

Dept Bacterial Infection and Host Responce,
Tokyo Medical and Dental Univ (TMDU), Tokyo,
Japan

The microbial-host interactions that drive the activation of the Nlrc4 inflammasome in<em>Shigella</em>-infected macrophages

Dec. 12(Tue.), 2017

Odd Number / 16:30-17:30, Exhibition Immune response to bacteial
Goro Matsuzaki Yuki Kinjo
infections
Even Number / 17:30-18:30 Hall

100138 1-C-W6-1-O/P

Presentation: 7min,
Discussion: 3min

Ota Mitsutoshi

Division of Psychoimmunology, Institute for<strong>NF-kB Arthritis Inducer 1 (NAI1) in chondrocytes regulates joint inflammation via
Genetic Medicine, Hokkaido University, Sapporo,
NF-kB activation</strong>Japan

Dec. 12(Tue.), 201714:55-16:15

Poster Presentation

Naoko KumagaiTakei

Department of Hygiene, Kawasaki Medical Scool, The analysis for function of human CD8+T cell line with and without long-term exposure toKurashiki, Japanasbestos fibers

Dec. 14(Thu.), 2017

Odd Number / 16:00-17:00, Exhibition (Immunosuppression andmodulation in tumor
Even Number / 17:00-18:00 Hall

Michio Miyajima

Laboratory for Mucosal Immunity, Center for
Systemic metabolic shift induced by PD-1 deficiency perturbs brain monoamines andIntegrative Medical Sciences, RIKEN Yokohama
emotional behaviour
Institute, Yokohama, JapanA ThPOK-independent CD4-skewed differentiation by loss of Tet proteins and SATB1<strong>GANP maintains antibody structural integrity during somatic
hypermutation</strong>

Dec. 13
14:25-15:45(Wed.), 2017

Venue

Exhibition
Cell therapyHall<strong>IFN-</strong><strong>&gamma;</strong><strong>-T-bet mediated metabolic

Center for Autoimmune Diseases, Division of
Hospital,Okayama, Japan

Institute of Industrial Science, the University ofTokyo, Tokyo, Japan

14:25-15:45

Room C

Tissue-specific immune
diseases II

NaozumiIshimaru

Hiroto Tsuboi

Toshihiko
Torigoe

Yoshihiro
Hayakawa

Tumor immunology-2

100139 3-D-W33-15-P

immunity)

100140 3-I-W43-15-O/P

Presentation: 7min,
Discussion: 3min

6 / 30Dec. 14(Thu.), 201714:25-15:45

Room IT cell-3 : T cell function

Harumi Suzuki Ei Wakamatsu

The 46th Annual Meeting of The Japanese Society for Immunology
Submission ID

Program No.

Oral Presentation Time

1st Author

Submission ID orderAffiliation

Title

Date

Time

Venue

Chair1Chair2

Odd Number / 16:30-17:30, Exhibition
Takayuki
Cytokines and chemokines-2
Even Number / 17:30-18:30 Hall
YoshimotoTakashi
Kobayashi

Session Title

100141 1-H-W16-13-P

Poster Presentation

Yasu-Taka Azuma

Laboratory of Veterinary Pharmacology, Divisionof Veterinary Science, Osaka Prefecture
Exacerbated TNBS-induced colitis in interleukin-19 knockout mice
University Graduate School of Life andEnvironmental Science, Izumisano, Japan

100142 2-C-W21-2-P

Poster Presentation

Hiroshi Hamana

Department of Innovative Cancer
Immunotherapy, Graduate School of Medicine
and Pharmaceutical Sciences, University of
Toyama, JapanT cell receptor (TCR) gene cloning from tumor infiltrating lymphocytes of breast cancer
patients toward TCR gene therapy

100143 2-B-W20-18-P

Poster Presentation

Yuki Tanaka

Psychoimmunology, Institute for Genetic
Medicine, Hokkaido University, Sapporo, Japan<strong>Enriched environment, which might suppresses the Gateway Reflex attenuated the Dec. 13
development of EAE via inhibiting immune cell accumulation in the L5 spinal cord.</strong> (Wed.), 2017

100144 1-E-W10-7-O/P

Presentation: 7min,
Discussion: 3min

Yasunobu Miyake

Division of Molecular and Cellular
Immunoscience, Department of Biomolecular
Sciences, Faculty of Medicine, Saga University,
Saga, Japan

Immunosuppressive receptor, Siglec binds to pathogenic fungus, <em>Trichophyton
mentagrophytes</em>, and negatively regulates host immune responses

Dec. 12(Tue.), 2017

100145 2-H-W24-14-P

Poster Presentation

Caroline M. Kijogi

Division of Immunology, Department of
Molecular Microbiology and Immunology,
Graduate School of Biomedical Sciences,
Nagasaki University, Nagasaki, Japan.

<strong>T-cell responses to <em>Plasmodium falciparum </em>and <em>Schistosoma
mansoni </em>infections in asymptomatic children living in the endemic region of Mbita,
western Kenya.</strong>

Dec. 13
16:00-17:00(Wed.), 2017

Exhibition Immune response to parasite Yoichi
infections
Hall
Maekawa

Masahiro
Yamamoto

100146 1-H-W16-4-O/P

Presentation: 6min,
Discussion: 2min

Yurina Miyajima

Laboratory for Innate Immune Systems, RIKEN
IMSFunction of BMP2 and BMP7 produced by ILC2 in the adipose tissue

Dec. 12(Tue.), 201714:55-16:15

Room H

Cytokines and chemokines-2

Takayuki
YoshimotoTakashi
Kobayashi

100147 3-B-W29-5-O/P

Presentation: 11min,
Discussion: 2min

Natsuko Otaki

Laboratory for Innate Immune Systems, RIKENIMSThe role of group 2 innate lymphoid cells in pulmonary fibrosis

Dec. 14(Thu.), 201714:25-15:45

Room B

Innate Lymphocyte-2(ILC1,2,3)

SusumuNAKAE

Shinichiro
SAWA

100148 3-C-W31-6-O/P

Presentation: 8min,
Discussion: 3min

Sayako Chiba

Division of Gastroenterology and Hepatology,
Department of Internal Medicine, Keio University Glycolysis regulates LPS-induced cytokine production in M2 polarized human macrophages
School of Medicine, Tokyo, Japan

Dec. 14(Thu.), 201714:25-15:45

Room C

Dendritic cells andTsuneyasu
Macrophages-3: Inflammatory
KaishoResponses

Rikinari
Hanayama

100149 3-C-W31-7-O/P

Presentation: 8min,
Discussion: 3min

Akihiro KimuraDept. of Immunology and Pathology, ResearchInstitute National Center for Global Health andMedicine, Chiba, Japan<strong>The novel ubiquitin ligase complex, NQO1-PDLIM2 inhibits TLR-dependent
production of selective cytokines by degrading I&kappa;B-&zeta;</strong>

Dec. 14(Thu.), 201714:25-15:45

Room C

Dendritic cells andTsuneyasu
Macrophages-3: Inflammatory
KaishoResponses

Rikinari
Hanayama

100150 1-H-W15-7-O/P

Presentation: 6min,
Discussion: 2min

Keiko Yoshimoto

Division of Rheumatology, Department ofInternal Medicine, Keio University School of
Medicine, Tokyo, Japan

BAFF signaling inhibitors ameliorate enhanced production of IL-6 and IL-10 by pSS
monocytes and consequently suppress IgG overproduction by affecting differentiation of B
cells.

Dec. 12(Tue.), 201713:20-14:40

Room H

Cytokines and chemokines-1

100151 3-G-W38-5-P

Poster Presentation

Kato Yasuhiro

Department of Respiratory Medicine and Clinical
Immunology, Graduate School of Medicine,The role of Stimulator of interferon genes (STING) in the pathogenesis of SLE
University of Osaka, Japan

Dec. 14(Thu.), 2017

100152 3-I-W43-12-P

Poster Presentation

Yumiko Kanno

Department of Immunology, Dokkyo Medical
University School of Medicine, Mibu,
Shimotsuga, Tochigi, Japan

100153 1-A-W2-3-P

Poster Presentation

Dong-Young Kim

100154 1-I-W17-15-O/P

Presentation: 7min,
Discussion: 3min

100155 3-F-W37-14-P

Dec. 12(Tue.), 2017

Dec. 13
16:00-17:00(Wed.), 2017

Exhibition
Cell therapy
Hall

Hiroaki Ikeda

Koji Tamada

16:00-17:00

Exhibition Systemic autoimmune
disease (1)Hall

Hitoshi
Kohsaka

Shinsuke
Yasuda14:55-16:15

Room E

Kazuyoshi
Kawakami

Hiromitsu Hara

Immune response to
mycobacteial and fungal
infections

Masaaki
Murakami

Akihiro Kimura

Odd Number / 16:00-17:00, Exhibition Systemic autoimmune
disease (2)Even Number / 17:00-18:00 Hall

Yoshiya Tanaka

Masayuki
NishideDec. 14(Thu.), 2017

Odd Number / 16:00-17:00, Exhibition
T cell-3 : T cell function
Even Number / 17:00-18:00 Hall

Harumi Suzuki Ei Wakamatsu

Department of Otorhinolaryngology-Head andAnti-allergic effect of intranasal vitamin D treatment by inhibiting dendritic cell activation in
Neck Surgery, Seoul National University College
the allergic rhinitis mouse modelof Medicine, Seoul, Korea

Dec. 12(Tue.), 2017

Odd Number / 16:30-17:30, Exhibition Allergy-2: Upper airway
allergic inflammation andEven Number / 17:30-18:30 Hall
allergic responses

Tomohiro
YoshimotoIwamoto Sanju

Division of Physiology and Pathology,
Department of Pharmacology, Toxicology andTherapeutics, Showa University of Pharmacy,
Tokyo, Japan

Atypical development of human Th17 lineage from na&iuml;ve CD4 T cells in psoriasis.

Dec. 12(Tue.), 201713:20-14:40

Koji Yasutomo Keishi Fujio

Poster Presentation

Hideo Kataoka

Department of Oral Microbiology, Showa
University School of Dentistry, Tokyo, JapanMALDI-TOF-MS Analysis of gut microbiota in murine model of food allergy

Dec. 14(Thu.), 2017

Odd Number / 16:00-17:00, Exhibition
Mucosal-Skin Immunity-3
Even Number / 17:00-18:00 Hall

100156 3-G-W38-3-O/P

Presentation: 7min,
Discussion: 4min

Yusuke Takeshima Graduate School of Medicine, the University ofTokyo, Tokyo, Japan

Comprehensive analysis of genome and transcriptome analysis of immune cell subsets inperipheral blood mononuclear cells (PBMCs) revealed mitochondria contribution in B cells
to systemic lupus erythematosus.

Dec. 14(Thu.), 201712:50-14:10

100157 3-B-W29-10-P

Poster Presentation

Shindo Ryodai

Toho University School of Medicine, Tokyo,
Japan<strong>ROR&gamma;t-positive cells mediate RIPK3- and MLKL-dependent lethal ileitis inneonatal mice</strong>

Dec. 14(Thu.), 2017

Odd Number / 16:00-17:00, Exhibition Innate Lymphocyte-2(ILC1,2,3)
Even Number / 17:00-18:00 Hall

100158 1-C-W5-4-O/P

Presentation: 7min,
Discussion: 3minFumitaka Sato

Kindai University, Osakasayama, Japan

Protective and detrimental effects of curdlan, a Th17 cell inducer, in immune-mediateddemyelination induced by a neurotropic viral infection

Dec. 12(Tue.), 201713:20-14:40

100159 3-E-W34-10-P

Poster Presentation

Shoya Yasuda

Department of Computational Intelligence andSystems Science, Tokyo Institute of Technology, Mathematical modeling of BAFFR-mediated B cell survival signa
Yokohama, Japan

Dec. 14(Thu.), 2017

100160 1-E-W10-4-O/P

Presentation: 7min,
Discussion: 3min

Shihoko KomineAizawa

Nihon University School of Medicine, Tokyo,
Japan

Induction of CD8<sup>+</sup>- MHC-I-restricted, antigen-specific T cells by recombinant
BCG protects against mycobacterial infection

Dec. 12(Tue.), 201714:55-16:15

100161 1-H-W15-11-P

Poster Presentation

Yuji Takeda

Department of Immunology, Yamagata University Analysis of cytokine signals using flow cytometry is useful for detection of contractive andFaculty of Medicine, Yamagata, Japan
fluctuating signals.

Dec. 12(Tue.), 2017

100162 2-A-W19-4-P

Poster Presentation

Masahisa Hemmi

Graduate School of Pharmaceutical Sciences,
Osaka University,Osaka, Japan

1Department of Allergy and Rheumatology,

HIF-1&alpha; plays a key role in regulation of homeostatic energy metabolism in cytotoxic T
lymphocytes.

Th17 promotes the induction of antigen-specific gut-mucosal CTLs following intramuscular
vaccination of an adenovirus vector

7 / 30

Room I

Human Immunology

Ryoji Yagi

Eiji Umemoto

Jun Kunisawa

Yoshiya Tanaka

Masayuki
NishideSusumuNAKAE

Shinichiro
SAWA

Mitsuru
Matsumoto

Daisuke
Kamimura

Odd Number / 16:00-17:00, Exhibition B cell development andfunction
Even Number / 17:00-18:00 Hall

Yoshiteru
Sasaki

Reiko Shinkura

Immune response to
mycobacteial and fungal
infections

Kazuyoshi
Kawakami

Hiromitsu Hara

Odd Number / 16:30-17:30, Exhibition
Masaaki
Cytokines and chemokines-1
Even Number / 17:30-18:30 Hall
Murakami

Akihiro Kimura

Dec. 13
16:00-17:00(Wed.), 2017

Room G

Room CRoom E

Systemic autoimmune
disease (2)Tissue-specific immune
diseases I

Exhibition
Mucosal-Skin Immunity-1
Hall

Kenji
Kabashima

Yoshiyuki Goto

The 46th Annual Meeting of The Japanese Society for Immunology
Submission ID

Program No.

Oral Presentation Time

1st Author

Submission ID orderAffiliation

Title

Date

Time

Transcriptional profile of human macrophages stimulated by ultra-high molecular weight
polyethylene particulate debris of orthopaedic implants uncovers a common gene
expression signature of rheumatoid arthritis

Dec. 14(Thu.), 2017

Protease allergen-induced local IL-17A production in skin tissue and accumulation of IL17A<sup>+</sup> &gamma;&delta; T cells in skin draining lymph nodes; possible
contribution to enhancement of skin eosinophilia and serum IgE response

Dec. 13
14:25-15:45(Wed.), 2017

Venue

Chair1Chair2

Exhibition Dendritic cells andTsuneyasu
Macrophages-3: Inflammatory
Hall
KaishoResponses

Rikinari
Hanayama

Allergy-3 : Allergic dermatitis,
food allergy and allergic
conjunctivitis

Tomohiro
Yoshimoto

Session Title

100163 3-C-W31-14-P

Poster Presentation

Mohamad Alaa
TerkawiDepartment of Orthopedic Surgery, Faculty of
Medicine and Graduate School of Medicine,
Hokkaido University, Sapporo, Japan

100164 2-G-W23-3-O/P

Presentation: 10min,
Discussion: 3min

Seiji Kamijo

Atopy (Allergy) Research Center, Juntendo
University Graduate School of Medicine, Tokyo,
Japan

100165 1-H-W16-14-P

Poster Presentation

Kyosuke Kanai

Department of Virology, Tottori University Faculty
Role of IL-35 in Lipopolysaccharide-Induced Airway Eosinophilia
of Medicine, Yonago, Japan

Dec. 12(Tue.), 2017

Odd Number / 16:30-17:30, Exhibition
Takayuki
Cytokines and chemokines-2
Even Number / 17:30-18:30 Hall
Yoshimoto

100166 3-A-W26-4-O/P

Presentation: 10min,
Discussion: 3min

Daisuke Kimura

Division of Immunology, Department of
Molecular Microbiology and Immunology,
Nagasaki University Graduate School of
Biomedical Sciences, Nagasaki, Japan

Dec. 14(Thu.), 201712:50-14:10

Room A

Tolerance and immune
suppression -1

100167 3-C-W31-9-O/P

Presentation: 8min,
Discussion: 3min

Takuya Yashiro

Department of Biological Science andTechnology, Faculty of lndustrial Science andDefect of NR4A3 leads to impaired ability of migration in intestinal dendritic cells
Technology, Tokyo University of Science, Tokyo,
Japan

Dec. 14(Thu.), 201714:25-15:45

Room C

Dendritic cells andTsuneyasu
Macrophages-3: Inflammatory
KaishoResponses

100168 2-H-W24-2-O/P

Presentation: 7min,
Discussion: 3min

Mana Miyakoda

Division of Immunology, Department of
Molecular Microbiology and Immunology,
Graduate School of Biomedical Sciences,
Nagasaki University

Mechanisms underlying metformin-mediated enhancement of the protective immune
responses against malaria infection.

Dec. 13
14:25-15:45(Wed.), 2017

Room H

Immune response to parasite
infections

100169 2-A-W19-6-P

Poster Presentation

Ito Sayami

Project for Vaccine and Immune Regulation,
Graduate School of Pharmaceutical Sciences,
Osaka University

Elucidation of the induction mechanism of transcutaneous immune responses with the selfdissolving microneedle patch

Dec. 13
16:00-17:00(Wed.), 2017

100170 1-D-W8-9-O/P

Presentation: 6min,
Discussion: 2.5min

Takahisa Kouwaki

Department of Immunology, Graduate school of
Medical Sciences, Faculty of Life Sciences,
Kumamoto University, Kumamoto, Japan<strong>Zyxin</strong> <strong>is a positive factor in a MAVS/IPS-1-dependent</strong><strong>type</strong> <strong>?</strong> <strong>interferon</strong><strong>expression pathway during viral infection.</strong>

Dec. 12(Tue.), 2017

100171 2-I-W25-9-P

Poster Presentation

Hideki Minematsu

Katayama Chemical Industries Co.,Ltd, Osaka,Japan

Effects of liposome-encapsulated clodronate which can deplete macrophages <em>invivo</em>.

100172 1-C-W6-6-O/P

Presentation: 7min,
Discussion: 3min

Tomomi Sato

100173 1-I-W18-6-P

Poster Presentation

100174 3-D-W32-2-PInterleukin-27-dependent loss of CD4<sup>+</sup> T cell-memory during malaria infection

Odd Number / 16:00-17:00,
Even Number / 17:00-18:00

Room G

Kenji Izuhara

Taku Okazaki

Takashi
Kobayashi
Shunsuke
Chikuma
Rikinari
Hanayama

Yoichi
Maekawa

Masahiro
Yamamoto

Exhibition
Mucosal-Skin Immunity-1
Hall

Kenji
Kabashima

Yoshiyuki Goto

Room D

Virus infection-2

Takashi Fujita

HiroyukiOshiumiDec. 13
16:00-17:00(Wed.), 2017

Exhibition Dendritic cells andMacrophages-1: OrganHall
specific Immune Tolerance

Satoshi Ishido

Kenichi Asano

Department of Fundamental Biosciences, Shiga Characterization of rheumatoid arthritis-associated interstitial pneumonia using collagenUniversity of Medical Science, Shiga, Japan
induced arthritis mice

Dec. 12(Tue.), 201714:55-16:15

Room C

NaozumiIshimaru

Hiroto Tsuboi

Nobumasa
Watanabe

Tokyo Metropolitan Institute of Medical Science,
Tokyo, Japan

MHC-II-dependent autonomous immune responses of in vitro-differentiated Th17 cells

Dec. 12(Tue.), 2017

Odd Number / 16:30-17:30, Exhibition
Helper T cells
Even Number / 17:30-18:30 Hall

Masakatsu
YAMASHITA

Motoko Y.
KIMURA

Poster Presentation

Ayumi Hongo

Department of Pathology, Sapporo Medical
University, Sapporo, Japan

Presence of proline in N-terminal extensions of epitope sequences influences HLA-A24
antigen processing and decreases CD8+ T-cell responses

Dec. 14(Thu.), 2017

Odd Number / 16:00-17:00, Exhibition Tumor immunology-1 (Tumor Yutaka
antigens, antigen presenting
Even Number / 17:00-18:00 Hall
Kawakami
cells, anti-tumor T cells)

Hirokazu
Matsushita

100175 3-F-W37-6-O/P

Presentation: 7min,
Discussion: 2min

Hideaki Takagi

Division of Immunology, Department of
Infectious Diseases, Faculty of Medicine,
University of Miyazaki

Tolerogenesis of gastrointestinal plasmacytoid dendritic cells impacts the induction of oral
tolerance

Dec. 14(Thu.), 201714:25-15:45

Eiji Umemoto

Jun Kunisawa

100176 1-F-W12-3-P

Poster Presentation

Makoto Kubo

Division of Immunology, Kitasato University
School of Allied Health Sciences, Kanagawa,Japan

Analysis of immune responses in prostate cancer patients received iridium-192 high-doserate prostate brachytherapy

Dec. 12(Tue.), 2017

Odd Number / 16:30-17:30, Exhibition Immune responses in cacer
immunotherapy
Even Number / 17:30-18:30 Hall

Toshihiko
Torigoe

Kenichiro Seino

100177 1-D-W8-4-O/P

Presentation: 6min,
Discussion: 2.5min

Takamasa Ueno

Center for AIDS Research, Kumamoto
University, Kumamoto, Japan<strong>Relative resistance of MHC-B to Nef-mediated downregulation is conserved
among primate lentiviruses and correlates with reduced viral loads in HIV-1-infectedindividuals</strong>

Dec. 12(Tue.), 201714:55-16:15

Room D

Virus infection-2

Takashi Fujita

HiroyukiOshiumi100178 3-I-W42-9-O/P

Presentation: 7min,
Discussion: 3min

Eun Jeong Park

Mie University Graduate School of Medicine,Mie, Japan&beta;7 integrin-mediated homing of exosomes to the gut

Dec. 14(Thu.), 201712:50-14:10

Room IT cell-2 : T cell signaling

SatoshiMatsudaTadashiYokosuka

100179 2-A-W19-1-P

Poster Presentation

Jianshi Jin

RIKEN Quantitative Biology Center (QBiC),
Osaka, Japan

A novel high-throughput method for bacteria counting based on <em>de-novo</em> 16S
rRNA sequence identification with single-base resolution

Dec. 13
16:00-17:00(Wed.), 2017

Exhibition
Mucosal-Skin Immunity-1
Hall

Kenji
Kabashima

Yoshiyuki Goto

100180 1-I-W17-14-O/P

Presentation: 7min,
Discussion: 3min

Daisuke SUZUKI

Center for iPS Cell Research and Application,
Kyoto University, Kyoto, Japan

Differential natural killer (NK) cell immunity against class-I human leukocyte antigen (HLA)knockout (KO) platelets and megakaryocytes

Dec. 12(Tue.), 201713:20-14:40

Room I

Human Immunology

Koji Yasutomo Keishi Fujio

100181 1-B-W3-7-O/P

Presentation: 7min,
Discussion: 2min

Ho Minh Van

Department of Emergency and Critical Care
Medicine, Graduate School of Biomedical and
Health Sciences, Hiroshima University<strong>Detection of ATP-dependent inflammatory suppression of the innate immune
response in septic patients</strong>

Dec. 12(Tue.), 201713:20-14:40

Room B

Endogenous innate immunity
and inflammation-1

Tatsuya Saitoh Takuya Uehata

100182 1-F-W11-5-P

Poster Presentation

Etsuko Harada

Department of Immunology, Mie University
School of Medicine, Mie, Japan<strong><em>Agaricus blazei</em></strong><strong> Murrill extract
inhibits</strong><strong> the expression of immune checkpoint molecules in a lung cancer
cell line</strong>

Dec. 12(Tue.), 2017

Odd Number / 16:30-17:30, Exhibition Combination cancer
Hiroyoshi
immunothrapy -beyond
Even Number / 17:30-18:30 Hall
immune checkpoint inhibitors- Nishikawa

100183 2-F-W22-13-P

Poster Presentation

Hiromichi Tsurui

Department of Pathology, Juntendo University
School of Medicine

Precise estimation of residue-residue interaction in TCR-pMHC complex by Fragment
Molecular Orbitan (FMO) calculation

Dec. 13
16:00-17:00(Wed.), 2017

100184 2-F-W22-2-O/P

Presentation: 8min,
Discussion: 3min

Katsuto Hozumi

Tokai University School of Medicine, Isehara,Japan

Molecular machinery for the maintenance of differentiation potential toward T/B cell lineages Dec. 13
in hematopoietic stem/progenitor cells by Lmo2
(Wed.), 20178 / 30

14:55-16:15

14:25-15:45

Room F

Tissue-specific immune
diseases II

Mucosal-Skin Immunity-3

Yoshihiro
Hayakawa

Exhibition T cell-1: T cell development
and repertoire selection
Hall

TaishinAkiyamaTakeshi Nitta

T cell-1: T cell development
and repertoire selection

TaishinAkiyamaTakeshi Nitta

Room F

The 46th Annual Meeting of The Japanese Society for Immunology
Submission ID

Program No.

Oral Presentation Time

1st Author

Submission ID orderAffiliation

Title

Date

Time

<strong>Clonal amplification of WT1 specific CTL using dendritic cell line.</strong>

Dec. 14(Thu.), 2017

Odd Number / 16:00-17:00,
Even Number / 17:00-18:00

Venue

Session Title
Tumor immunology-2
Exhibition (Immunosuppression andmodulation in tumor
Hall
immunity)

100185 3-D-W33-10-P

Poster Presentation

Wakana Goto

Laboratory of Hematology and Oncology,
Graduate School of Health Sciences, Niigata
University, Japan

100186 3-D-W32-11-O/P

Presentation: 7min,
Discussion: 3min

Hisashi Kanemaru

Research Institute for Microbial Diseases(RIMD), Osaka University, Osaka, Japan

Basic leucine zipper transcription factor ATF-like 2 exhibits an anti-tumor effect throughupregulation of IL-12 p40 expression

Dec. 14(Thu.), 201712:50-14:10

Room D

100187 3-I-W43-1-O/P

Presentation: 7min,
Discussion: 3min

Jisu Ma

Department of Immunoparasitology, ResearchInstitute for Microbial Diseases, Osaka
University, Osaka, Japan<strong>PLC&beta; plays an important role in CD8 T cell-mediated host defense against<em>Toxoplasma gondii</em></strong>

Dec. 14(Thu.), 201714:25-15:45

100188 1-B-W3-5-O/P

Presentation: 7min,
Discussion: 2min

Naoya Sakaguchi

Research Institute for Microbial Diseases(RIMD), Osaka University, Osaka, Japan<strong>Role of GABARAP subfamily in the regulation of non-canonical inflammasome
activation</strong>

Dec. 12(Tue.), 2017

100189 1-A-W1-9-O/P

Presentation: 7min,
Discussion: 3min

Aiko Saku

Department of Allergy and Clinical Immunology,
Graduate School of Medicine, Chiba University,
Chiba, Japan

Lung epithelial fucosylation promotes the development of house dust mite (HDM)-induced
allergic airway inflammation.

100190 3-D-W32-1-O/P

Presentation: 7min,
Discussion: 3min

Yasuhiro Kikuchi

Department of Pathology, Sapporo Medical
University School of Medicine, Sapporo, Japan

A novel HLA class I peptide encoded by a long non-coding RNA

100191 2-B-W20-3-P

Poster Presentation

Atsushi Nomura

Department of Immunology, Juntendo University
Comparative analysis of neuroinflammation in Lupus-prone mice
School of Medicine, Tokyo, Japan

Dec. 13
16:00-17:00(Wed.), 2017

Exhibition Systemic autoimmune
disease (1)Hall100192 1-F-W12-6-O/P

Presentation: 10min,
Discussion: 3min

Kikuya Sugiura

Department of Advanced Pathobiology, Graduate
Manipulation of tumor microenvironment by cytokine gene transfection enhances dendritic
School of Life and Environmental Sciences,
Osaka Prefecture University, Izumisano, Japan cell-based immunotherapy

Dec. 12(Tue.), 201714:55-16:15

Room F

100193 1-H-W15-12-P

Poster Presentation

YAMAMOTO
ShinyaDivision of Chemotherapy, Kindai University
Faculty of Pharmacy, Osaka, Japan

A highly active form of lymphotactin/XCL1 (XCL1-CC3) functions as a potent adjuvant toaccumulate CD103+XCR1+ cross-presenting dendritic cells and induce CD8+ CTLmediated antitumor and antiviral effects

100194 3-I-W42-2-P

Poster Presentation

Saitoh Kodai

Department of Immunology, Faculty of
Pharmaceutical Sciences, Hokkaido University,
Hokkaido, Japan

100195 1-H-W15-13-P

Poster Presentation

KAMBARA
Hirokazu

100196 2-B-W20-7-O/P

Presentation: 7min,
Discussion: 3min

100197 1-H-W15-14-P

Chair1Chair2

Toshihiko
Torigoe

Yoshihiro
Hayakawa

Tumor immunology-1 (Tumor
antigens, antigen presenting
cells, anti-tumor T cells)

YutakaKawakami

Hirokazu
Matsushita

Room IT cell-3 : T cell function

Harumi Suzuki Ei Wakamatsu

13:20-14:40

Room B

Endogenous innate immunity
and inflammation-1

Tatsuya Saitoh Takuya Uehata

Dec. 12(Tue.), 201713:20-14:40

Room A

Allergy-1 : Lower airway
allergic inflammation

Kenji Izuhara

Koubun Yasuda

Dec. 14(Thu.), 201712:50-14:10

Room D

Tumor immunology-1 (Tumor
antigens, antigen presenting
cells, anti-tumor T cells)

YutakaKawakami

Hirokazu
Matsushita

Hitoshi
Kohsaka

Shinsuke
YasudaToshihiko
Torigoe

Kenichiro Seino

Dec. 12(Tue.), 2017

Odd Number / 16:30-17:30, Exhibition
Masaaki
Cytokines and chemokines-1
Even Number / 17:30-18:30 Hall
Murakami

Akihiro Kimura

A role of STAP-2 in T cell activation and T cell-mediated immune responses

Dec. 14(Thu.), 2017

Odd Number / 16:00-17:00, Exhibition
T cell-2 : T cell signaling
Even Number / 17:00-18:00 Hall

TadashiYokosuka

Division of Chemotherapy, Kindai University
Faculty of Pharmacy, Osaka, Japan

CCL28-deficiency altered microbiota in the colon and aggravated DSS-induced colitis in
mice

Dec. 12(Tue.), 2017

Odd Number / 16:30-17:30, Exhibition
Masaaki
Cytokines and chemokines-1
Even Number / 17:30-18:30 Hall
Murakami

Shin-Ichiroh Saitoh of Tokyo, Tokyo, Japan.

The Institute of Medical Science, The University

ADP-libosylation factor-like 8b is required for pathogenesis of mouse models of Systemic
Lupus Erythematosus

Dec. 13
14:25-15:45(Wed.), 2017

Poster Presentation

MATSUO
Kazuhiko

Division of Chemotherapy, Kindai University
Faculty of Pharmacy, Osaka, Japan

CCR4 is involved in atopic dermatitis-like skin lesions induced by topical sensitization ofovalbumin and &delta;-toxin using a hydrogel patch in mice

Dec. 12(Tue.), 2017

Odd Number / 16:30-17:30, Exhibition
Masaaki
Cytokines and chemokines-1
Even Number / 17:30-18:30 Hall
Murakami

Akihiro Kimura

100198 3-E-W34-2-O/P

Presentation: 7min,
Discussion: 3min

Hisashi Nomura

Department of Dermatology, Keio University
School of Medicine, Tokyo, Japan

Fc&gamma;RIIb plays an important role in maintaining clonal ignorance and prevents
pemphigus phenotype in pathogenic anti-desmoglein 3 antibody knock-in mice

Dec. 14(Thu.), 201712:50-14:10

Room EB cell development andfunction

Yoshiteru
Sasaki

Reiko Shinkura100199 1-A-W1-14-O/P

Presentation: 7min,
Discussion: 3min

Katsuhide Okunishi Gunma University, Maebashi, Japan

Rab27 effector exophilin5 regulates IL-33 signaling in allergic immune responses

Dec. 12(Tue.), 201713:20-14:40

Room A

Allergy-1 : Lower airway
allergic inflammation

Kenji Izuhara

Koubun Yasuda

100200 1-F-W12-7-P

Poster Presentation

Mariko Takami

Department of Medical Immunology, Graduate
School of Medicine, Chiba University, Chiba,Japan

AhR signaling enhances the moDC function to activate NKT cells

Dec. 12(Tue.), 2017

Odd Number / 16:30-17:30, Exhibition Immune responses in cacer
immunotherapy
Even Number / 17:30-18:30 Hall

Toshihiko
Torigoe

Kenichiro Seino

100201 2-G-W23-4-P

Poster Presentation

Worawalun
HIRUNWIDCHAY
ARAT

Department of Molecular Immunology, Graduate Site-specific regulation of oral mucosa-recruiting CD8<sup>+</sup> T cells -Comparison of
School, Tokyo Medical and Dental University.
contact allergy between skin and oral mucosa-

Dec. 13
16:00-17:00(Wed.), 2017

100202 1-B-W4-11-P

Poster Presentation

HAI T PHUNG

Department of Microbiology and Immunology,
TNF receptor-associated factors 5 expressed in non-hematopoietic cells augments acuteTohoku University Graduate School of Medicine,colonic damage induced by dextran sulfate sodium
Sendai, Japan

Dec. 12(Tue.), 2017

Odd Number / 16:30-17:30, Exhibition Endogenous innate immunity Osamu
and inflammation-2
Even Number / 17:30-18:30 Hall
Takeuchi

SachikoTakamura(Akashi)

100203 1-A-W2-11-P

Poster Presentation

Hirotomo
Shibaguchi

Department of Biochemistry, Faculty of
Medicine, Fukuoka University, Fukuoka, Japan

Gene analysis of HL-60 cells and neutrophils to generate ideal chemotactic cells for HiSAT

Dec. 12(Tue.), 2017

Odd Number / 16:30-17:30, Exhibition Allergy-2: Upper airway
allergic inflammation andEven Number / 17:30-18:30 Hall
allergic responses

Tomohiro
YoshimotoRyoji Yagi

100204 1-G-W13-8-O/P

Presentation: 6min,
Discussion: 2min

Yohei Kawano

Department of Immune Regulation, Tokyo
Medical and Dental Universiy Graduate School,
Tokyo, Japan

Establishment of a novel culture system for long-term proliferating hematopoietic progenitors
Dec. 12with lymphoid and myeloid potential from normal mouse bone marrow without genetic(Tue.), 2017
manipulations

13:20-14:40

Room G

Hematopoiesis and immune
environments

TakashiNagasawa

HitoshiTakizawa

100205 1-A-W2-12-O/P

Presentation: 7min,
Discussion: 3min

Shihono Kato

Laboratory for Innate Immune Systems, RIKEN, Role of ILC2 in the formation of maternal allergic inflammation and allergic susceptibility of
IMS, Kanagawa, Japanthe offspring

Dec. 12(Tue.), 201714:55-16:15

Room A

Allergy-2: Upper airway
allergic inflammation andallergic responses

Tomohiro
YoshimotoRyoji Yagi

100206 2-H-W24-10-O/P

Presentation: 7min,
Discussion: 3minOdsuren
Sukhbaatar

Department of Molecular Microbiology and
Immunology, Nagasaki University Graduate
School of Biomedical Science, Nagasaki, Japan

Dec. 13
14:25-15:45(Wed.), 2017

Room H

Immune response to parasite
infections

Yoichi
Maekawa

Masahiro
Yamamoto

Institute for Molecular and Cellular Regulation,

Role of Interleukin-27 in the regulation of immune responses against chronic malaria
infection

9 / 30

Room B

Immune responses in cacer
immunotherapy

Systemic autoimmune
disease (1)SatoshiMatsudaHitoshi
KohsakaExhibition Allergy-3 : Allergic dermatitis,
food allergy and allergic
Kenji IzuharaHallconjunctivitis

Akihiro Kimura
Shinsuke
YasudaTomohiro
YoshimotoThe 46th Annual Meeting of The Japanese Society for Immunology
Submission ID

Program No.

Oral Presentation Time

1st Author

Submission ID orderAffiliation

Title

Date

Time

Venue

Session Title

Chair1Chair2100207 1-I-W18-4-O/P

Presentation: 7min,
Discussion: 3min

Yuko Okuyama

Department of Microbiology and Immunology,
A new regulator of OX40 co-signaling controls autoimmune neuroinflammation mediated by
Tohoku University Graduate School of Medicine,CD4<sup>+</sup> T cells
Miyagi, Japan

100208 3-C-W31-12-O/P

Presentation: 8min,
Discussion: 3min

Takeshi Nakatani

Department of respiratory medicine and clinicalimmunology, Osaka Univ., Osaka, Japan

Yusuke Takahashi

Department of Immunology, Graduate School of
1</strong><strong><sup>&minus;</sup></strong><strong>CD137</strong><strong><supMedicine and Pharmaceutical Science,>&minus;</sup></strong><strong> tumor infiltrating lymphocytes in various
University of Toyama, Japan

Dec. 13
16:00-17:00(Wed.), 2017

Exhibition
Cell therapy
Hall

Hiroaki Ikeda

Koji Tamada

Immuno Technology Section, Vaccine Research Development of Chimeric Antigen Receptor (CAR)-Transduced CD8 T cells Using SIVCenter, NIAID, NIH
specific Neutralizing Anibodies

Dec. 12(Tue.), 201714:55-16:15

Room D

Takashi Fujita

HiroyukiOshiumiDec. 14(Thu.), 2017

Odd Number / 16:00-17:00, Exhibition
T cell-3 : T cell function
Even Number / 17:00-18:00 Hall

Lamtor1 (p18) plays a crucial role in trafficking of dendritic cells.

<strong>T cell receptor repertoire of PD-1<sup>+</sup>CD137<sup>+</sup> and PD-

100209 2-C-W21-3-P

Poster Presentation

cancers</strong>

Dec. 12(Tue.), 201714:55-16:15

Room I

Helper T cells

Masakatsu
YAMASHITA

Dec. 14(Thu.), 201714:25-15:45

Room C

Dendritic cells andTsuneyasu
Macrophages-3: Inflammatory
KaishoResponses

Motoko Y.
KIMURA
Rikinari
Hanayama

100210 1-D-W8-6-O/P

Presentation: 6min,
Discussion: 2.5min

Nami Iwamoto

100211 3-I-W43-4-P

Poster Presentation

Tomohiro Masuda 名古屋市昭和区

Growth factor Midkine promotes NFAT activation and Th1 differentiation in lupus Nephritis

100212 1-B-W4-13-P

Poster Presentation

Masaaki Toda

Dept of Immunology<strong>Epigenetic mechanisms mediate the antiatherosclerotic activity of low consumption Dec. 12of alcohol</strong>(Tue.), 2017

100213 2-G-W23-15-P

Poster Presentation

Chang-Hyun Kim

College of Medicine, Dongguk University,
Gyeonggi-do, South Korea

Protective effects of agonistic anti-4-1BB antibody on the development of imiquimodinduced psoriasis-like dermatitis in mice

Dec. 13
16:00-17:00(Wed.), 2017

Exhibition Allergy-3 : Allergic dermatitis,
food allergy and allergic
Kenji IzuharaHallconjunctivitis

100214 3-C-W30-13-O/P

Presentation: 7min,
Discussion: 3min

Masafumi
Nakayama

Frontier Research Institute for Interdisciplinary
Sciences, Tohoku University

Identification of a silica receptor associated with canonical inflammasome activation.

Dec. 14(Thu.), 201712:50-14:10

Room C

100215 3-H-W41-8-P

Poster Presentation

Taizo Mori

Department of Immune Regulation, The
Research Center for Hepatitis and Immunology,
Research Institute, National Center for Global
Health and Medicine

Lnk/Sh2b3 regulates adipose inflammation and glucose tolerance through group1-ILCs

Dec. 14(Thu.), 2017

Odd Number / 16:00-17:00, Exhibition Tissue-specific immune
diseases III
Even Number / 17:00-18:00 Hall

100216 1-B-W3-3-O/P

Presentation: 7min,
Discussion: 2min

Ken Takashima

Department of Immunology, Graduate School ofNovel Negative Regulators for MDA5-Mediated Innate Immune Response
Medicine, Hokkaido University, Sapporo, Japan

Dec. 12(Tue.), 201713:20-14:40

100217 3-F-W36-10-P

Poster Presentation

Katsuhiro
NakanishiLaboratory of Microbiology and Immunology,
School of Pharmaceutical Sciences, University of Production of secretory hybrid-IgG/IgA in plant expression system
Shizuoka, Shizuoka, Japan

Dec. 14(Thu.), 2017

Odd Number / 16:00-17:00, Exhibition
Mucosal-Skin Immunity-2
Even Number / 17:00-18:00 Hall

Koji Hase

Gyohei Egawa

100218 1-A-W1-16-P

Poster Presentation

Prince Baffour
Tonto

Dept. of Immunology<strong>Role of eosinophils and metalloproteinase-2 in airway remodeling</strong>

Dec. 12(Tue.), 2017

Odd Number / 16:30-17:30, Exhibition Allergy-1 : Lower airway
allergic inflammation
Even Number / 17:30-18:30 Hall

Kenji Izuhara

Koubun Yasuda

100219 2-H-W24-12-O/P

Presentation: 7min,
Discussion: 3minShin-Ichi Inoue

Department of Infectious Diseases, Kyorin
University School of Medicine, Tokyo, Japan<strong>Maintenance of immunological memory to malaria is impaired by<em>Salmonella</em> infection</strong>

Dec. 13
14:25-15:45(Wed.), 2017

Room H

Yoichi
Maekawa

Masahiro
Yamamoto

100220 2-I-W25-10-P

Poster Presentation

Hiroki HIRAMA

Laboratory of Immunology, Graduate School of
Health Sciences, Niigata University, Niigata,Japan

The effects of ovariectomy on autoimmune hepatitis and hepatic dendritic cells.

Dec. 13
16:00-17:00(Wed.), 2017

Exhibition Dendritic cells andMacrophages-1: OrganHall
specific Immune Tolerance

Satoshi Ishido

Kenichi Asano

100221 3-F-W37-15-O/P

Presentation: 7min,
Discussion: 2min

Hidehiko Suzuki

Laboratory of Vaccine Materials and Laboratoryof Gut Environmental System, National
Institutes of Biomedical Innovation, Health andNutrition (NIBIOHN)

Development of divalent food poisoning vaccine by augmented antigenicity of<em>Clostridium perfringens</em> enterotoxin

Dec. 14(Thu.), 201714:25-15:45

Room F

Mucosal-Skin Immunity-3

Eiji Umemoto

Jun Kunisawa

100222 3-G-W39-4-O/P

Presentation: 7min,
Discussion: 4min

Haruka Tsuchiya

Department of Allergy and Rheumatology, The
University of Tokyo, Tokyo, Japan

Identification EP300 as a Novel Therapeutic Target for Rheumatoid Arthritis by theComprehensive Analysis of Fibroblast-like Synoviocytes

Dec. 14(Thu.), 201714:25-15:45

Room G

Systemic autoimmune
disease (3)KimitoKawahata

ShingoNakayamada

100223 3-C-W30-7-P

Poster Presentation

Atsuo Nakamura

Dairy Science and Technology Institute, Kyodo
Milk Industry Co. Ltd.,Tokyo, Japan<strong>Effect of polyamines on macrophage polarization and mucosal
inflammation</strong>

Dec. 14(Thu.), 2017

Odd Number / 16:00-17:00, Exhibition Dendritic cells andTomohiko
Macrophages-2: Development
Even Number / 17:00-18:00 Hall
Tamuraand Recognition

100224 1-F-W12-12-O/P

Presentation: 10min,
Discussion: 3min

Serina Tokita

Department of Pathology, Sapporo Medical
University School of Medicine, Sapporo, Japan

HLA-A24 ligandome analysis identifies a neoantigen that elicits strong CTL responses

Dec. 12(Tue.), 201714:55-16:15

100225 3-H-W40-7-P

Poster Presentation

Nobuhiro Nakano

Atopy (Allergy) Research Center, Juntendo
University Graduate School of Medicine, Tokyo,
Japan

Mast cells acquire intestinal antigen-presenting cell-like properties by Notch signaling

Dec. 14(Thu.), 2017

100226 1-D-W7-10-O/P

Presentation: 6min,
Discussion: 2min

Akihiko Komuro

Niigata University of Pharmacy and Applied Life
Sciences, Niigata, Japan

A possible role of TAR-RNA binding protein phosphorylation in MDA5/LGP2-mediatedcellular responses by Cardiovirus infection

100227 1-D-W8-10-P

Poster Presentation

Yoshihiro Kumagai Nippon Medical School, Tokyo, Japan

100228 1-F-W11-2-P

Poster Presentation

Ouji-Sageshima
NorikoDepartment of Microbiology and Immunology,

Department of Immunology, Nara Medical
University, Kashihara, Japan

Virus infection-2

Harumi Suzuki Ei Wakamatsu

Odd Number / 16:30-17:30, Exhibition Endogenous innate immunity Osamu
and inflammation-2
Even Number / 17:30-18:30 Hall
TakeuchiRoom B

Dendritic cells andTomohiko
Macrophages-2: Development
Tamuraand Recognition

Endogenous innate immunity
and inflammation-1

Immune response to parasite
infections

Keishi Fujio

SachikoTakamura(Akashi)Tomohiro
Yoshimoto
Masafumi
Nakayama
MotomuHashimoto

Tatsuya Saitoh Takuya Uehata

Masafumi
Nakayama

Toshihiko
Torigoe

Kenichiro Seino

Odd Number / 16:00-17:00, Exhibition
Granulocyte & Mast cells
Even Number / 17:00-18:00 Hall

Atsuhito Nakao

YosukeKurashima

Dec. 12(Tue.), 201713:20-14:40

Taro Kawai

Mitsutoshi
Yoneyama<strong>THE ANALYSIS OF THE INTERACTION BETWEEN HIV-1 GP 120 AND</strong><strong>b-CHEMOKINE RECEPTOR BY USING MULITIVALENT V3
EPITOPES GRAFTED AT IMMUNOGLOBULIN HYPERVARIABLE REGIONS </strong>

Dec. 12(Tue.), 2017

Odd Number / 16:30-17:30, Exhibition
Virus infection-2
Even Number / 17:30-18:30 Hall

Takashi Fujita

HiroyukiOshiumi

The critical role of HLA class Ib proteins, HLA-E and HLA-F, expressed on tumor cells

Dec. 12(Tue.), 2017

Odd Number / 16:30-17:30, Exhibition Combination cancer
Hiroyoshi
immunothrapy -beyond
Even Number / 17:30-18:30 Hall
immune checkpoint inhibitors- Nishikawa

10 / 30

Room F

Room D

Immune responses in cacer
immunotherapy

Virus infection-1

Yoshihiro
Hayakawa

The 46th Annual Meeting of The Japanese Society for Immunology
Submission ID

Program No.

Oral Presentation Time

Submission ID order

1st Author

Affiliation

Title

Date

Time

Venue

Session Title

Chair1Chair2100229 1-G-W13-11-P

Poster Presentation

Akihisa Oda

Chiba, Japan<strong>Niche-induced myeloproliferative-like disease caused by overexpression of Tlx1
i<em>n situ </em>in splenic stromal cells</strong>

Dec. 12(Tue.), 2017

Odd Number / 16:30-17:30, Exhibition Hematopoiesis and immune
environments
Even Number / 17:30-18:30 Hall

TakashiNagasawa

HitoshiTakizawa

100230 3-E-W34-9-P

Poster Presentation

Hanbing Xue

Graduate School of Life and Environmental
Sciences, University of Tsukuba, Ibaraki, Japan

Examination of &ldquo;Universal Light Chain&rdquo; models that can be paired with a wide
spectrum of immunoglobulin heavy chains maintaining their antigen-binding specificities

Dec. 14(Thu.), 2017

Odd Number / 16:00-17:00, Exhibition B cell development andfunction
Even Number / 17:00-18:00 Hall

Yoshiteru
Sasaki

Reiko ShinkuraInstitute for Environmental and Gender Specific100231 1-C-W6-10-P

Poster Presentation

Hayakawa Kunihiro Medicine, Juntendo University Graduate School fatty acids

Possible mechanisms of anti-arthritic effect induced by dietary &omega;-3 polyunsaturated

Dec. 12(Tue.), 2017

Odd Number / 16:30-17:30, Exhibition Tissue-specific immune
diseases II
Even Number / 17:30-18:30 Hall

NaozumiIshimaru

Hiroto Tsuboi

100232 1-A-W2-13-O/P

Presentation: 7min,
Discussion: 3min

Mio Ohashi

Department of Immunoregulation, Institute ofMedical Science, Tokyo Medical University,
Tokyo, Japan

Prediction of Chemical Respiratory and Contact Sensitizers by OX40L Expressionin
Dendritic Cells Using a Novel 3D Co-Culture System

Dec. 12(Tue.), 201714:55-16:15

Room A

Allergy-2: Upper airway
allergic inflammation andallergic responses

Tomohiro
YoshimotoRyoji Yagi

Presentation: 10min,
Discussion: 3min

Division of Immune Regulation, Institute for100233 3-A-W26-1-O/P

Takumi Maruhashi Genome Research, Tokushima University,
Tokushima, Japan

Immuno-inhibitory co-receptor LAG-3 regulates immunodominance and autoimmunity by
virtue of its conformation-dependent recognition of MHCII

Dec. 14(Thu.), 201712:50-14:10

Room A

Tolerance and immune
suppression -1

Taku Okazaki

Shunsuke
Chikuma

100234 3-C-W31-4-P

Poster Presentation

Naho Ikari

Research &amp; Development Division,
Kikkoman Corporation, Chiba, Japan

Double-stranded RNA in lactic acid bacteria augments Th1 immunity via IFN-&beta;
secretion by human dendritic cells

Dec. 14(Thu.), 2017

Odd Number / 16:00-17:00, Exhibition Dendritic cells andTsuneyasu
Macrophages-3: Inflammatory
Even Number / 17:00-18:00 Hall
KaishoResponses

Rikinari
Hanayama

Division of Cancer Biology and Therapeutics,

100235 1-A-W1-5-P

Poster Presentation

Ryuichi Nagashima Miyagi Cancer Certer Reserch Institute, Natori,<strong>Nrf2 activation suppressed lung allergic inflammation induced by type2-innate
lymphoid cells.</strong>

Dec. 12(Tue.), 2017

Odd Number / 16:30-17:30, Exhibition Allergy-1 : Lower airway
allergic inflammation
Even Number / 17:30-18:30 Hall

Kenji Izuhara

Koubun Yasuda

100236 3-G-W39-3-P

Poster Presentation

Shinji Maeda

Dec. 14(Thu.), 2017

Odd Number / 16:00-17:00, Exhibition Systemic autoimmune
disease (3)Even Number / 17:00-18:00 Hall

KimitoKawahata

ShingoNakayamada

100237 3-C-W30-1-O/P

Presentation: 7min,
Discussion: 3minJeong-Hwan Yoon National University Hospital, Daegu, Korea

Repression of SMAD3 by STAT3 and c-SKI is essential for conventional dendritic celldifferentiation

Dec. 14(Thu.), 201712:50-14:10

Room C

Dendritic cells andTomohiko
Macrophages-2: Development
Tamuraand Recognition

Masafumi
Nakayama

100238 2-H-W24-4-O/P

Presentation: 7min,
Discussion: 3min

Sayuri Nakamae

Division of Immunology, Department of
Molecular Microbiology and Immunology,
Nakgasaki University Graduate School of
Biomedical Sciences, Nagasaki, Japan

Modulation of T-cell immune responses to pathogenic malaria parasites by prior infection
with different species of malaria parasites

Dec. 13
14:25-15:45(Wed.), 2017

Room H

Immune response to parasite
infections

Yoichi
Maekawa

Masahiro
Yamamoto

100239 3-A-W26-12-P

Poster Presentation

Manabu Kinoshita

Department of Immunology and Microbiology,
National Defense medical College, Saitama,Japan<strong>LPS tolerance recruits CD11b<sup>+</sup> macrophages to the liver withenhanced bactericidal activity and low TNF-releasing capability, resulting in drastic
resistance to lethal septicemia</strong>

Dec. 14(Thu.), 2017

Odd Number / 16:00-17:00, Exhibition Tolerance and immune
suppression -1
Even Number / 17:00-18:00 Hall

Taku Okazaki

Shunsuke
Chikuma

100240 3-C-W30-2-O/P

Presentation: 7min,
Discussion: 3min

Haruka Sasaki

Department of Immunology, Yokohama City
University Graduate School of Medicine,
Yokohama, Japan

A novel distal enhancer responsible for <em>Irf8</em> expression in the mononuclear
phagocyte lineage

Dec. 14(Thu.), 201712:50-14:10

Room C

Dendritic cells andTomohiko
Macrophages-2: Development
Tamuraand Recognition

100241 1-G-W13-12-O/P

Presentation: 6min,
Discussion: 2min

Akihisa Oda

Research Institute for Biomedical Sciences
Tokyo Universitiy of Science, Chiba, Japan<strong>Niche-induced myeloproliferative-like disease caused by overexpression of Tlx1
i<em>n situ </em>in splenic stromal cells</strong>

Dec. 12(Tue.), 201713:20-14:40

Room G

Hematopoiesis and immune
environments

TakashiNagasawa

HitoshiTakizawa

100242 1-D-W7-3-O/P

Presentation: 6min,
Discussion: 2min

Natsuko Imakita

Department of Immunology, Nara Medical
University, Nara, JapanThe contribution of histone methyltransferase Setdb2 in the pathogenesis of influenza
associated encephalopathy

Dec. 12(Tue.), 201713:20-14:40

Room D

Virus infection-1

Taro Kawai

Mitsutoshi
Yoneyama

100243 3-F-W36-11-O/P

Presentation: 7min,
Discussion: 3min

Tadashi Takeuchi

Laboratory for Intestinal Ecosystem, RIKEN
Center for Integrative Medical Sciences

Gut microbial metabolite acetate modulates affinity of IgA to maintain intestinal homeostasis

Dec. 14(Thu.), 201712:50-14:10

Room F

Mucosal-Skin Immunity-2

Koji Hase

Gyohei Egawa

100244 1-G-W13-13-P

Poster Presentation

Ueno Yuta

Laboratory of Molecular Biology and
Immunology, Department of Biological Scienceand Technology, Tokyo University of Science<strong>Two mesenchymal progenitor cell populations in the spleen defined by a novel
three-dimensional culture system</strong>

Dec. 12(Tue.), 2017

Odd Number / 16:30-17:30, Exhibition Hematopoiesis and immune
environments
Even Number / 17:30-18:30 Hall

TakashiNagasawa

HitoshiTakizawa

100245 3-E-W35-10-P

Poster Presentation

Mizuki Ishikawa

Akita University, Graduate School of Engineering
Science, Laboratory for Molecular Cell
Regulatory mechanism for intracellular sorting of Parm1 by NPxY motif.
Physiology, Akita, Japan

Dec. 14(Thu.), 2017

Odd Number / 16:00-17:00, Exhibition Germinal center reaction and
Masaki Hikida
plasma cells
Even Number / 17:00-18:00 Hall

Wataru Ise

100246 1-D-W7-6-O/P

Presentation: 6min,
Discussion: 2min

Masaaki Okamoto

Department of Immunology, Graduate School of<strong>Circulating miR-451a in extracellular vesicles regulate innate immune cells
Medical Sciences, Kumamoto University,
response to influenza A virus vaccine</strong>
Kumamoto, Japan

Dec. 12(Tue.), 201713:20-14:40

Taro Kawai

Mitsutoshi
Yoneyama

100247 3-H-W40-8-P

Poster Presentation

Izumi Fujigaki

Department of Biological Science andSuppression of mast cell-mediated allergic responses by valerate, butyrate, and niacin via
Technology, Tokyo University of Science, Tokyo,
GPR109a.
Japan

Dec. 14(Thu.), 2017

Odd Number / 16:00-17:00, Exhibition
Granulocyte & Mast cells
Even Number / 17:00-18:00 Hall

Atsuhito Nakao

YosukeKurashima100248 3-H-W40-9-P

Poster Presentation

Yuki Nakamura

Department of Immunology, Faculty of Medicine,
Regulation of plasma histamine levels by the mast cell clock and its modulation by stress
University of Yamanashi, Japan

Dec. 14(Thu.), 2017

Odd Number / 16:00-17:00, Exhibition
Granulocyte & Mast cells
Even Number / 17:00-18:00 Hall

Atsuhito Nakao

YosukeKurashima100249 1-A-W2-4-P

Poster Presentation

Ayumi Fukuoka

Department of Immunology, Hyogo College ofMedicine, Nishinomiya, Hyogo, Japan

Cystatin SN inhibits Japanese cedar pollen-induced allergic rhinitis in mice.

Dec. 12(Tue.), 2017

Odd Number / 16:30-17:30, Exhibition Allergy-2: Upper airway
allergic inflammation andEven Number / 17:30-18:30 Hall
allergic responses

Tomohiro
YoshimotoRyoji Yagi

100250 1-E-W10-6-P

Poster Presentation

Masahiro
Kitabatake

Department of Immunology, Nara Medical
University, Nara, Japan<strong>CD8<sup>+</sup> T cells play a critical role for the murine model of immune
reconstitution inflammatory syndrome.</strong>

Dec. 12(Tue.), 2017

Odd Number / 16:30-17:30, Exhibition Immune response to
mycobacteial and fungal
Even Number / 17:30-18:30 Hall
infections

Kazuyoshi
Kawakami

Hiromitsu Haraof Medicine, Chiba, JapanJapan

Department of Respiratory Medicine, Allergy and<strong>Exploratory study of T cell biomarkers predicting Abatacept treatment response in
Clinical Immunology, Nagoya City University
RA patients with background adjustment by IPW method</strong>
Graduate School of Medical Sciences

Biomedical Research Institute, Kyungpook

11 / 30

Room D

Virus infection-1

Masafumi
Nakayama

The 46th Annual Meeting of The Japanese Society for Immunology
Submission ID

Program No.

Oral Presentation Time

1st Author

Submission ID orderAffiliation

Title

Date

Time

Venue

Session Title

Chair1100251 3-A-W26-2-O/P

Presentation: 10min,
Discussion: 3min

Hikari Okamura

Division of Immune Regulation, Institute for
Genome Research, Tokushima University

Single-cell analysis of autoreactive T cells under the control of PD-1

Dec. 14(Thu.), 201712:50-14:10

Room A

Tolerance and immune
suppression -1

100252 3-C-W31-8-O/P

Presentation: 8min,
Discussion: 3min

Rimpei MORITA

Department of Immunology, International
University of Health and Welfare, School of
Medicine, Narita, Japan

Clathrin heavy chain is an NLRP3 partner for NLRP3 inflammasome activation

Dec. 14(Thu.), 201714:25-15:45

Room C

Dendritic cells andTsuneyasu
Macrophages-3: Inflammatory
KaishoResponses

100253 3-F-W37-7-O/P

Presentation: 7min,
Discussion: 2min

Takashi Kanaya

Laboratory for Intestinal Ecosystem, RIKEN
Center for Integrative Medical Sciences,
Yokohama, Kanagawa, Japan

IL-22 binding protein (IL-22BP) regulates the properties of follicle-associated epithelium(FAE) to facilitate antigen uptake into Peyer&rsquo;s patches

Dec. 14(Thu.), 201714:25-15:45

Room F

Mucosal-Skin Immunity-3

100254 1-G-W13-3-P

Poster Presentation

Takahiro Noguchi

Department of Immunology and Cell Biology,
Osaka University Graduate School of Medicine,
Osaka, Japan

Dynamic analysis of hematopoietic stem cells in vivo by using intravital imaging techniques

Dec. 12(Tue.), 2017

Odd Number / 16:30-17:30, Exhibition Hematopoiesis and immune
environments
Even Number / 17:30-18:30 Hall100255 3-G-W39-5-O/P

Presentation: 7min,
Discussion: 4min

Shinsuke Yasuda

Department of Rheumatology, Endocrinology and <strong>RasGRP-Ras-MAPK activation in </strong><strong>fibroblast-like synoviocytes
Nephrology, Faculty of Medicine and Graduate
from patients with rheumatoid arthritis and inhibition of this pathway by Ras
School of Medicine, Hokkaido University,translocation</strong>
Sapporo, Japan

Dec. 14(Thu.), 201714:25-15:45

100256 2-I-W25-11-P

Poster Presentation

Seiki Shirai

Laboratory of Nano-design for Innovative Drug
Development, Graduate School of
Pharmaceutical Sciences, Osaka University

Development of dendritic cell-targeting peptides that induce antigen-specific immune
tolerance

Dec. 13
16:00-17:00(Wed.), 2017

100257 2-A-W19-13-P

Poster Presentation

Airi Masaki

Department of Plastic and Reconstructive
Surgery, Tohoku University school, Miyagi,
Japan

Critical role of interferon (IFN) - &gamma; in the skin wound healing

100258 2-A-W19-9-O/P

Presentation: 7min,
Discussion: 3min

Emi Furusawa

Department of Molecular Immunology , Tokyo
Medical and Dental University,Tokyo,Japan

Silencing of B7-DC/PD-L2 in the cutaneous dendritic cells using siRNA inhibits contact
allergy100259 1-F-W12-8-P

Poster Presentation

Kazuki Misato

Vaccine Creation Project, BIKEN Innovative
Vaccine Research Alliance Laboratories,
Development of a cancer vaccine by using dendritic cell-targeting peptide
Research Institute for Microbial Diseases, Osaka
University

100260 3-C-W31-1-P

Poster Presentation

Yoshiyuki Miyazaki Fukuoka, Japan

100261 1-D-W8-11-P

Poster Presentation

Tomotaka
OkamuraTsukuba Primate Research Center, National
Institutes of Biomedical Innovation, Health andNutrition, Ibaraki Japan

100262 3-I-W43-8-O/P

Presentation: 7min,
Discussion: 3min

100263 1-D-W8-8-O/P

Taku Okazaki

Chair2
Shunsuke
Chikuma
Rikinari
Hanayama

Eiji Umemoto

Jun Kunisawa

TakashiNagasawa

HitoshiTakizawa

KimitoKawahata

ShingoNakayamada

Exhibition Dendritic cells andMacrophages-1: OrganHall
specific Immune Tolerance

Satoshi Ishido

Kenichi Asano

Dec. 13
16:00-17:00(Wed.), 2017

Exhibition
Mucosal-Skin Immunity-1
Hall

Kenji
Kabashima

Yoshiyuki Goto

Dec. 13
14:25-15:45(Wed.), 2017

Room A

Kenji
Kabashima

Yoshiyuki Goto

Toshihiko
Torigoe

Kenichiro Seino

Room G

Systemic autoimmune
disease (3)Mucosal-Skin Immunity-1

Dec. 12(Tue.), 2017

Odd Number / 16:30-17:30, Exhibition Immune responses in cacer
immunotherapy
Even Number / 17:30-18:30 Hall

The induction of macrophage activation by a sulfated polysaccharide fucoidan

Dec. 14(Thu.), 2017

Odd Number / 16:00-17:00, Exhibition Dendritic cells andTsuneyasu
Macrophages-3: Inflammatory
Even Number / 17:00-18:00 Hall
KaishoResponses

Rikinari
Hanayama

Non-pathogenic AIDS virus carrying an adjuvant molecule induced strong cellular immunityand long-term protective efficacy against pathogenic SHIV.

Dec. 12(Tue.), 2017

Odd Number / 16:30-17:30, Exhibition
Virus infection-2
Even Number / 17:30-18:30 Hall

Takashi Fujita

HiroyukiOshiumiMohammad A
SAYEM

Division of Cellular Signaling, Advanced Institute<strong>IL-8 has a negative role on tumor infiltrating CD8<sup>+</sup> T cells in variousof Medical Research, Keio University School ofcancers</strong>
Medicine, Tokyo, Japan

Dec. 14(Thu.), 201714:25-15:45

Room IT cell-3 : T cell function

Harumi Suzuki Ei Wakamatsu

Presentation: 6min,
Discussion: 2.5min

Takuya Sueyoshi

Laboratory of Molecular Immunobiology,
Graduate School of Biological Sciences, Nara
Institute of Science and Technology (NAIST),Nara, Japan

RNA-binding protein Hu antigen R (HuR) plays an important role in antiviral innate immune
responses via mRNA stabilization

Dec. 12(Tue.), 201714:55-16:15

Room D

Virus infection-2

Takashi Fujita

HiroyukiOshiumi100264 2-A-W19-14-O/P

Presentation: 7min,
Discussion: 3minMari Tenno

Department of Immune Regulation ResearchInstitute National Center for Global Health andMedicine, Chiba, Japan

Disruption of Lnk increases severity of dextran sulfate sodium-induced acute colonicinflammation

Dec. 13
14:25-15:45(Wed.), 2017

Room A

Mucosal-Skin Immunity-1

Kenji
Kabashima

Yoshiyuki Goto

100265 1-D-W7-12-P

Poster Presentation

Keiko Nagata

Division of Molecular Pathology, Department of
Pathology, Faculty of Medicine, Tottori
University, Yonago, Japan

ImmunoglobulinG4 production is induced by reactivation of Epstein-Barr virus persistent in
B lymphocytes from Graves&rsquo; disease patients and controls

Dec. 12(Tue.), 2017

Odd Number / 16:30-17:30, Exhibition
Virus infection-1
Even Number / 17:30-18:30 Hall

Taro Kawai

Mitsutoshi
Yoneyama

100266 1-D-W7-8-O/P

Presentation: 6min,
Discussion: 2min

Haruna Okude

Laboratory of Molecular Immunobiology, Nara
Induction of cell death by imiquimod (R837) and its role in immune responses
Institute of Science and Technology, Nara, Japan

Dec. 12(Tue.), 201713:20-14:40

Taro Kawai

Mitsutoshi
Yoneyama

100267 3-A-W27-2-P

Poster Presentation

Akane Hara

Graduate School of Systems Life Sciences,
Kyushu University, Fukuoka, Japan

Theoretical study of relationship between allergy and intestinal microbiome.

Dec. 14(Thu.), 2017

Odd Number / 16:00-17:00, Exhibition Tolerance and immune
suppression -2
Even Number / 17:00-18:00 Hall

Naganari
OhkuraTakashi Sekiya

100268 1-A-W1-10-O/P

Presentation: 7min,
Discussion: 3min

Tomomitsu
Miyasaka

Division of Pathophysiology, Department ofPharmaceutical Sciences, Faculty of
Pharmaceutical Sciences, Tohoku Medical andPharmaceutical University, Sendai, Japan

Possible involvement of CD103<sup>+</sup> dendritic cells in female-predominant Th2
priming in asthma

Dec. 12(Tue.), 201713:20-14:40

Kenji Izuhara

Koubun Yasuda

100269 3-C-W31-10-P

Poster Presentation

Shiori Nakano

Department of Biological Science and
NR4A3 is involved in function of migratory DCs and activation of T cells in FITC-induced
Technology, Faculty of Industrial Science andTechnology, Tokyo University of Science, Tokyo, contact hypersensitivity
Japan

Dec. 14(Thu.), 2017

Odd Number / 16:00-17:00, Exhibition Dendritic cells andTsuneyasu
Macrophages-3: Inflammatory
Even Number / 17:00-18:00 Hall
KaishoResponses

100270 1-B-W4-8-O/P

Presentation: 7min,
Discussion: 2min

Kafi N. Ealey

Laboratory for Innate Immune Systems, RIKEN
IMS, Yokohama, Japan

Mechanisms for the regulation of adipose tissue expansion and remodeling by group 2
innate lymphoid cells

Dec. 12(Tue.), 201714:55-16:15

100271 2-F-W22-3-P

Poster Presentation

Shinji Fujimoto

Institute for Frontier Life and Medical Sciences,
Kyoto University, Kyoto, Japan

D1V14(inverted), an oddly rearranged <em>Tcrb</em> in normal thymus

Dec. 13
16:00-17:00(Wed.), 2017

100272 3-E-W34-15-P

Poster Presentation

MiyokoMatsushima

Department of Pathophysiological Laboratory
Sciences, Nagoya University Graduate School of <strong>Deteriorated amount of IC capture without CD40 on B cells</strong>
Medicine, Nagoya, Japan

Faculty of Agriculture, Kyushu University,

12 / 30

Dec. 14(Thu.), 2017

Room D

Room A

Virus infection-1

Allergy-1 : Lower airway
allergic inflammation

Rikinari
Hanayama

Endogenous innate immunity
and inflammation-2

Osamu
Takeuchi

SachikoTakamura(Akashi)Exhibition T cell-1: T cell development
and repertoire selection
Hall

TaishinAkiyamaTakeshi Nitta

Yoshiteru
Sasaki

Reiko Shinkura

Room B

Odd Number / 16:00-17:00, Exhibition B cell development andfunction
Even Number / 17:00-18:00 Hall

The 46th Annual Meeting of The Japanese Society for Immunology
Submission ID

Program No.

Oral Presentation Time

1st Author

Submission ID orderAffiliation

100273 3-F-W37-18-P

Poster Presentation

Yuki Kanai

Laboratory of Nano-design for Innovative Drug
Development, Graduate School of
Pharmaceutical Sciences, Osaka University

100274 1-E-W10-3-O/P

Presentation: 7min,
Discussion: 3min

Naoto Nouchi

100275 3-C-W31-3-P

Poster Presentation

100276 3-H-W40-10-P

Title

Date

Time

Venue

Session Title

Chair1Chair2

Eiji Umemoto

Jun Kunisawa

Kazuyoshi
Kawakami

Hiromitsu Hara

Dec. 14(Thu.), 2017

Odd Number / 16:00-17:00, Exhibition
Mucosal-Skin Immunity-3
Even Number / 17:00-18:00 Hall

Division of Host Defense, Medical Institute ofearly effector cells but does not inhibit exhaustion following <em>Mycobacterium
Bioregulation, Kushu University, Fukuoka, Japan

Dec. 12(Tue.), 201714:55-16:15

Kazuko Atsumi

Department of Pathophysiological Laboratory
Sciences, Nagoya University Graduate School of <strong>Analysis on signal pathway in pro-inflammatory response by diazinon</strong>
Medicine, Nagoya, Japan

Dec. 14(Thu.), 2017

Odd Number / 16:00-17:00, Exhibition Dendritic cells andTsuneyasu
Macrophages-3: Inflammatory
Even Number / 17:00-18:00 Hall
KaishoResponses

Rikinari
Hanayama

Poster Presentation

Azusa Kageyama

Department of Biological Science andTechnology, Tokyo University of Science, Tokyo, Physiological significance of IL-10 produced by mucosal type mast cells
Japan

Dec. 14(Thu.), 2017

Odd Number / 16:00-17:00, Exhibition
Granulocyte & Mast cells
Even Number / 17:00-18:00 Hall

Atsuhito Nakao

YosukeKurashima

100277 3-H-W41-5-P

Poster Presentation

Natsumi Kikuchi

Department of Biosciences, School of Science,
Kitasato University, Kanagawa, JapanThe roles of ILC3 and &gamma;&delta; T cells in the development of colitis of the modelmice

Dec. 14(Thu.), 2017

Odd Number / 16:00-17:00, Exhibition Tissue-specific immune
diseases III
Even Number / 17:00-18:00 Hall

Keishi Fujio

MotomuHashimoto100278 1-I-W17-16-O/P

Presentation: 7min,
Discussion: 3minNozomi Kuse

Center for AIDS Research, Kumamoto
University, Kumamoto, Japan<strong>Effective priming of functional HIV-1-specific CD8<sup>+</sup> T Cells fromna&iuml;ve T cells using STING ligand</strong>

Dec. 12(Tue.), 201713:20-14:40

Room I

Human Immunology

Koji Yasutomo Keishi Fujio

100279 1-H-W16-2-O/P

Presentation: 6min,
Discussion: 2min

Koki Hirashima

Department of immunology, Graduate School of
Pharmaceutical Sciences, Hokkaido University<strong>Tyk2 positively regulates <em>P. acnes</em>-induced acuteinflammation</strong>

Dec. 12(Tue.), 201714:55-16:15

Room H

Cytokines and chemokines-2

Takayuki
YoshimotoTakashi
Kobayashi

100280 2-A-W19-18-P

Poster Presentation

Atsushi Nishida

Shiga University of Medical Science, Otsu,
Japan

Expression of Human Cathelicidin Peptide LL-37 in Inflammatory Bowel Disease

Dec. 13
16:00-17:00(Wed.), 2017

Kenji
Kabashima

Yoshiyuki Goto

100281 3-H-W40-11-P

Poster Presentation

Takahiro Arai

Department of Biological Science andTechnology, Tokyo University of Science, Tokyo, Transcriptional regulation of basophil-specific proteases
Japan

Atsuhito Nakao

YosukeKurashima100282 2-A-W19-12-P

Poster Presentation

Ryuta Muromoto

Faculty of Pharmaceutical Sciences, Hokkaido
University, Sapporo, Japan

Basal STAT3 activity maintained by TYK2 is required for IL-17-induced I&kappa;B-&zeta;
expression in keratinocytes

Dec. 13
16:00-17:00(Wed.), 2017

Exhibition
Mucosal-Skin Immunity-1
Hall

Kenji
Kabashima

Yoshiyuki Goto

100283 1-E-W10-5-O/P

Presentation: 7min,
Discussion: 3min

Yusuke Tsujimura

Tsukuba Primate Research Center, National
Institutes of Biomedical Innovation, Health andNutrition, Ibaraki, Japan

The immune responses induced by BCG vaccination in the non-human primate TB modelDec. 12(Tue.), 201714:55-16:15

Room E

Immune response to
mycobacteial and fungal
infections

Kazuyoshi
Kawakami

Hiromitsu Hara

100284 3-H-W40-12-P

Poster Presentation

Megumi Iwasaki

Department of Biological Science andGeneration of mutant mouse Fc&epsilon;RI&alpha;, which can be expressed as
Technology, Tokyo University of Science, Tokyo,&alpha;&gamma;<sub>2</sub> trimer and can bind to mouse IgE with high affinity
Japan

Dec. 14(Thu.), 2017

Odd Number / 16:00-17:00, Exhibition
Granulocyte & Mast cells
Even Number / 17:00-18:00 Hall

Atsuhito Nakao

YosukeKurashima100285 1-F-W12-4-O/P

Presentation: 10min,
Discussion: 3min

Takeshi Yamada

System Biology,Kanazawa
university,Kanazawa,Japan<strong>Features of immune response induced </strong><strong>by</strong><strong>Gemcitabine in </strong><strong>pancreatic ductal
adenocarcinoma</strong> <strong>model</strong>

Dec. 12(Tue.), 201714:55-16:15

Room F

Immune responses in cacer
immunotherapy

Toshihiko
Torigoe

Kenichiro Seino

100286 3-B-W28-5-O/P

Presentation: 11min,
Discussion: 2min

Hiroshi Watarai

Division of Stem Cell Cellomics, Institute ofMedical Science, University of Tokyo<strong>A Novel Mouse Model of iNKT Cell-deficiency Generated by CRISPR/Cas9
Technology Reveals a Pathogenic Role of iNKT Cells in Metabolic Disease</strong>

Dec. 14(Thu.), 201712:50-14:10

Room B

Innate Lymphocyte-1 (NKT,
MAIT, gdT, NK)

Kensuke
ShibataKazuyaIWABUCHI

100287 2-I-W25-14-P

Poster Presentation

Miya Yoshino

Division of Immunology, Department of
Molecular and Cellular Biology, School of Life
Science, Faculty of Medicine, Tottori University,
Yonago , Japan

Measurement of the transport of skin self-antigens under inflammatory conditions

Dec. 13
16:00-17:00(Wed.), 2017

Satoshi Ishido

Kenichi Asano

100288 1-A-W2-5-P

Poster Presentation

Makoto Matsui

Department of Fundamental Biosciences, Shiga
Role of neutrophils in the nasal mucosa in a mouse model of allergic rhinitis
University of Medical Science, Otsu, Japan

Dec. 12(Tue.), 2017

Odd Number / 16:30-17:30, Exhibition Allergy-2: Upper airway
allergic inflammation andEven Number / 17:30-18:30 Hall
allergic responses

Tomohiro
YoshimotoRyoji Yagi

100289 3-C-W30-6-P

Poster Presentation

Hidetoshi Nara

Department of Immunology, Yamagata University Interleukin21 arrests bone marrow derived dendritic cells PD-L1 high immunosuppressive
Faculty of Medicine, Yamagata, Japan
state

Dec. 14(Thu.), 2017

Odd Number / 16:00-17:00, Exhibition Dendritic cells andTomohiko
Macrophages-2: Development
Even Number / 17:00-18:00 Hall
Tamuraand Recognition

Masafumi
Nakayama

100290 3-C-W30-9-O/P

Presentation: 7min,
Discussion: 3min

Ryo Okada

Dept. of integrated Biosciences, Grad. school offrontier Sciences, The university of Tokyo,
Tokyo, Japan

Dec. 14(Thu.), 201712:50-14:10

Room C

Dendritic cells andTomohiko
Macrophages-2: Development
Tamuraand Recognition

Masafumi
Nakayama

100291 1-A-W1-17-O/P

Presentation: 7min,
Discussion: 3minKazuyuki
Nakagome

Department of Respiratory Medicine and Allergy
Elevated periostin concentrations in the bronchoalveolar lavage fluid of eosinophilic
Center, Saitama Medical University, Saitama,pneumoniaJapan

Dec. 12(Tue.), 201713:20-14:40

Room A

Allergy-1 : Lower airway
allergic inflammation

Kenji Izuhara

Koubun Yasuda

100292 1-A-W2-6-P

Poster Presentation

Daisuke Nagakubo University of Medical Science, Otsu, Japan

Involvement of CCL28 in the pathogenesis of allergic rhinitis in a mouse modelDec. 12(Tue.), 2017

Odd Number / 16:30-17:30, Exhibition Allergy-2: Upper airway
allergic inflammation andEven Number / 17:30-18:30 Hall
allergic responses

Tomohiro
YoshimotoRyoji Yagi

100293 3-F-W36-14-O/P

Presentation: 7min,
Discussion: 3min

Mayuri Tanaka

Laboratory of Adjuvant Innovation, Center for
Vaccine and Adjuvant Research, National
Institutes of Biomedical Innovation, Health andNutrition, Osaka, Japan

Essential role of CARD14 in murine experimental psoriasis

Dec. 14(Thu.), 201712:50-14:10

Koji Hase

Gyohei Egawa

100294 1-I-W18-18-P

Poster Presentation

Hayato Yabe

Research Institute for Frontier Medicine ,Regulatory mechanisms of the production of IgG4 in IgG4-related dacryoadenitis andSapporo Medical University School of Medicine ,sialadenitis
Hokkaido , Japan

Dec. 12(Tue.), 2017

Odd Number / 16:30-17:30, Exhibition
Helper T cells
Even Number / 17:30-18:30 Hall

Masakatsu
YAMASHITA

Motoko Y.
KIMURA

Pulmonary vaccine against lung cancer developed using dendritic cell-targeting peptide

IL-21 signaling drives differentiation of short-lived effector CD8<sup>+</sup>T cells frombovis</em> Bacillus Calmette-Gu&eacute;rin infection in mice

Department of Fundamental Biosciences, Shiga

Distribution of DCIR4 among various tissue-resident macrophages

13 / 30

Dec. 14(Thu.), 2017

Room E

Immune response to
mycobacteial and fungal
infections

Exhibition
Mucosal-Skin Immunity-1
Hall

Odd Number / 16:00-17:00, Exhibition
Granulocyte & Mast cells
Even Number / 17:00-18:00 Hall

Exhibition Dendritic cells andMacrophages-1: OrganHall
specific Immune Tolerance

Room F

Mucosal-Skin Immunity-2

The 46th Annual Meeting of The Japanese Society for Immunology
Submission ID

Program No.

Oral Presentation Time

1st Author

Submission ID orderAffiliation

Title

Date

Time

Venue

Session Title

Chair1Chair2100295 3-E-W34-16-P

Poster Presentation

Haruka Saito

Department of Biosciences, School of Science,
Kitasato University, Kanagawa, Japan

Rab13 prevents development of B cell lymphoma

Dec. 14(Thu.), 2017

Odd Number / 16:00-17:00, Exhibition B cell development andfunction
Even Number / 17:00-18:00 Hall

Yoshiteru
Sasaki

100297 1-I-W17-3-O/P

Presentation: 7min,
Discussion: 3min

RyutaroIWABUCHI

Department of Life Science and Medical
Bioscience, Waseda University, Tokyo, Japan

Human GM-CSF and Flt3-L induce reconstitution and maturation of human myeloid
dendritic cells in humanized mice

Dec. 12(Tue.), 201713:20-14:40

Room I

Human Immunology

Koji Yasutomo Keishi Fujio

100298 1-A-W1-1-O/P

Presentation: 7min,
Discussion: 3min

Sho SHIBATA

Department of Immune Regulation, Tokyo
Medical and Dental University, Tokyo, Japan

Monocyte-derived macrophages in the lung contribute to the development of pulmonary
emphysema through MMP-12 production in a mouse model of COPD

Dec. 12(Tue.), 201713:20-14:40

Room A

Allergy-1 : Lower airway
allergic inflammation

Kenji Izuhara

Koubun Yasuda

100299 3-D-W33-2-O/P

Presentation: 7min,
Discussion: 3min

Ibuki Harada

Department of Immunology, Yokohama City
University Graduate School of Medicine,
Yokohama, Japan<strong>Soluble factors produced by BCR-ABL-positive leukemic cells may compromise
antitumor immunity in chronic myeloid leukemia </strong>

Dec. 14(Thu.), 201714:25-15:45

Room D

Tumor immunology-2(Immunosuppression andmodulation in tumor
immunity)Toshihiko
Torigoe

Yoshihiro
Hayakawa

100300 1-A-W2-7-O/P

Presentation: 7min,
Discussion: 3min

Masaya Matsuda

Laboratory of Immunopharmacology, Faculty of
Pharmaceutical Sciences, Setsunan University,
Osaka, Japan

Effects of subcutaneous immunotherapy (SCIT) on regulatory T cells in pollinosis patients

Dec. 12(Tue.), 201714:55-16:15

Room A

Allergy-2: Upper airway
allergic inflammation andallergic responses

Tomohiro
YoshimotoRyoji Yagi

100301 1-A-W1-2-P

Poster Presentation

Minoru Takeuchi

Dept. of Animal Medical Science, Kyoto Sangyo
University, Kyoto, Japan<strong>Effect of H</strong><strong>ot Water Extract from Agaricus Blazei Murill on
Lipopolysaccharide (LPS) -induced Lung Inflammation and the Immunological
Mechanism</strong>

Dec. 12(Tue.), 2017

Odd Number / 16:30-17:30, Exhibition Allergy-1 : Lower airway
allergic inflammation
Even Number / 17:30-18:30 Hall

Kenji Izuhara

Koubun Yasuda

100302 1-G-W13-18-O/P

Presentation: 6min,
Discussion: 2min

Arata Takeuchi

Department of Immunology, Graduate School ofSix different types of mesenchymal stromal cells provide the framework of multi-layered
Medical and Dental Sciences, Niigata University,
subcompartments in lymph node
Niigata, Japan

Dec. 12(Tue.), 201713:20-14:40

TakashiNagasawa

HitoshiTakizawa

100303 3-C-W31-11-P

Poster Presentation

Yuna Uchida

Department of Biological Science andTechnology, Tokyo University of Science, Tokyo, The role of NR4A3 in the gene expression and function of dendritic cells
Japan

Dec. 14(Thu.), 2017

Odd Number / 16:00-17:00, Exhibition Dendritic cells andTsuneyasu
Macrophages-3: Inflammatory
Even Number / 17:00-18:00 Hall
KaishoResponses

Rikinari
Hanayama

100304 1-E-W10-8-O/P

Presentation: 7min,
Discussion: 3min

Daiki Tanno

Department of Medical Microbiology, Mycology
and Immunology, Tohoku University Graduate
School of Medicine

Dectin-2-mediated signaling triggered by the cell wall structures of <em>Cryptococcus
neoformans</em>

Dec. 12(Tue.), 201714:55-16:15

100305 3-H-W41-6-P

Poster Presentation

Shigeki Sakai

Department of Medicine, Shiga University of
Medical Science, Shiga, Japan

Bortezomib suppresses the development of experimental colitis by inhibiting the activation of Dec. 14
NF-&kappa;B(Thu.), 2017

100306 2-A-W19-7-P

Poster Presentation

Kanae Niimi

International Education and Research Center for
Development of immune and microbial environments is independently regulated in the
Food and Agricultural Immunology, Graduate
School of Agricultural Science, Tohoku
mammary gland
University, Miyagi, Japan

Dec. 13
16:00-17:00(Wed.), 2017

Exhibition
Mucosal-Skin Immunity-1
Hall100307 3-G-W38-6-O/P

Presentation: 7min,
Discussion: 4min

Yukiko Iwasaki

Department of Allergy and Rheumatology,
Graduate School of Medicine, The University ofTokyo, Japan

Plasma metabolomic analysis combined with transcriptome data has potential for
stratification of SLE patients

Dec. 14(Thu.), 201712:50-14:10

Room G

100308 1-H-W16-5-O/P

Presentation: 6min,
Discussion: 2min

Ippei Koshi

Department of Molecular and Cellular
Immunology, Shinshu University Graduate
School of Medicine

Branching cytokine signals for an effector function and cell survival via a discrete common&beta; chain subregion in murine primary basophils

Dec. 12(Tue.), 201714:55-16:15

100309 1-H-W15-8-O/P

Presentation: 6min,
Discussion: 2min

Mizoguchi Izuru

Department of Immunoregulation, Institute ofMedical Science, Tokyo Medical University,
Tokyo, Japan<strong>A Novel Role for Epstein-Barr Virus-Induced Gene 3 to Augment IL-23 Receptor</strong><strong>&alpha;</strong> <strong>Protein Expression through A Lectin
Chaperone Calnexin </strong>

Dec. 12(Tue.), 201713:20-14:40

100310 3-H-W41-7-P

Poster Presentation

Miki Matsui

Department of Pharmacology, Kyoto
Pharmaceutical University, Kyoto, JapanThe role of Ca<sup>2+</sup>-activated K<sup>+</sup> channel K<sub>Ca</sub>3.1 inmesenteric lymph node CD4<sup>+ </sup>T cells of chemically-induced murine
inflammatory bowel disease modelDec. 14(Thu.), 2017

100311 1-A-W2-14-O/P

Presentation: 7min,
Discussion: 3min

Kano Tanabe

Department of Medical Technology, Kumamoto
Health Science University, Kumamoto, Japan

CaMKII regulates IgE class switch recombination via TRAF3 ubiquitination

Dec. 12(Tue.), 201714:55-16:15

100312 1-G-W13-7-O/P

Presentation: 6min,
Discussion: 2minJunichiro Takano

Laboratory for Immune Regeneration, RIKEN
Center for Integrative Medical Sciences,
Yokohama, Japan<strong>Varinat PRC1.1 is required for specification of hematopoietic progenitor cells
toward B lymphoid lineage</strong>

Dec. 12(Tue.), 2017

100313 1-D-W8-2-O/P

Presentation: 6min,
Discussion: 2.5min

Hayato Murakoshi

Center for AIDS Research, Kumamoto
University, Kumamoto, Japan

Impact of a single escape mutation selected by HLA-A*24:02-restricted CD8<sup>+</sup>T cells on HIV-1 control by HLA-B*35:01-restricted ones and T cell adaptation

100314 3-G-W39-11-O/P

Presentation: 7min,
Discussion: 4min

Sugimori Yusuke

Department of Allergy and Rheumatology,
Graduate School of Medicine, The University ofTokyo, Tokyo, Japan

100315 3-E-W34-5-O/P

Presentation: 7min,
Discussion: 3min

Akihiko Muto

100316 1-B-W4-12-P

Poster Presentation

100317 1-A-W2-15-P

Poster Presentation

Room G

Hematopoiesis and immune
environments

Reiko Shinkura

Immune response to
mycobacteial and fungal
infections

Kazuyoshi
Kawakami

Hiromitsu Hara

Odd Number / 16:00-17:00, Exhibition Tissue-specific immune
diseases III
Even Number / 17:00-18:00 Hall

Keishi Fujio

MotomuHashimotoKenjiKabashima

Yoshiyuki Goto

Systemic autoimmune
disease (2)Yoshiya Tanaka

Masayuki
NishideRoom H

Cytokines and chemokines-2

Takayuki
YoshimotoTakashi
Kobayashi

Room H

Cytokines and chemokines-1

Masaaki
Murakami

Akihiro Kimura

Odd Number / 16:00-17:00, Exhibition Tissue-specific immune
diseases III
Even Number / 17:00-18:00 Hall

Keishi Fujio

MotomuHashimoto

Room A

Allergy-2: Upper airway
allergic inflammation andallergic responses

Tomohiro
YoshimotoRyoji Yagi

13:20-14:40

Room G

Hematopoiesis and immune
environments

TakashiNagasawa

HitoshiTakizawa

Dec. 12(Tue.), 201714:55-16:15

Room D

Virus infection-2

Takashi Fujita

HiroyukiOshiumiComprehensive Flow Cytometric Analysis of Immune Cell Subsets in PBMCs from
Idiopathic Inflammatory Myopathy Patients

Dec. 14(Thu.), 201714:25-15:45

Room G

Systemic autoimmune
disease (3)KimitoKawahata

ShingoNakayamada

Department of Biochemistry, Tohoku University
Graduate School of Medicine, Miyagi, Japan

Single-cell analysis of gene regulatory network in activated B cells

Dec. 14(Thu.), 201712:50-14:10

Room EB cell development andfunction

Yoshiteru
Sasaki

Reiko Shinkura

Kyohei Nishino

Department of Medicine, Shiga University of
Medical Science

Analysis of the role of autophay in dextran sodium sulfate (DSS) induced experimental colitis

Dec. 12(Tue.), 2017

Odd Number / 16:30-17:30, Exhibition Endogenous innate immunity Osamu
and inflammation-2
Even Number / 17:30-18:30 Hall
Takeuchi

SachikoTakamura(Akashi)Akira Awaya

Dermatology&amp;Epidemiology ResearchInstitute(DERI),Totsuka,Yokohama, Japan

Strategy for advance of melanocyte immunology from research on pollen-induced
diseases(PID) such as Kawasaki disease(KD) - Epidemiological study of KD(13): Statisticalanalyses reveal epidemics of Influenza suppress or postpone KD onsets. Coadministration

Dec. 12(Tue.), 2017

Odd Number / 16:30-17:30, Exhibition Allergy-2: Upper airway
allergic inflammation andEven Number / 17:30-18:30 Hall
allergic responses

Ryoji Yagi

14 / 30

Room E

Tomohiro
YoshimotoThe 46th Annual Meeting of The Japanese Society for Immunology
Submission ID

Program No.

Oral Presentation Time

Submission ID order

1st Author

Affiliation

Title

Date

Time

Venue

Session Title

Room H

Cytokines and chemokines-2

Chair1Chair2

Takayuki
YoshimotoTakashi
Kobayashi

100318 1-H-W16-6-O/P

Presentation: 6min,
Discussion: 2min

Yuki Hikichi

Laboratory for Innate Immune Systems, RIKEN
Center for Integrative Medical Sciences

Post-transcriptional regulation of type 2 cytokine gene expression in ILC2

Dec. 12(Tue.), 201714:55-16:15

100319 1-E-W9-13-P

Poster Presentation

Yoshihiko Sugitani

Department of Medicine, Shiga University of
Medical Science, Otsu, JapanThe therapeutic effects of elemental diet and intestnal microbiota

Dec. 12(Tue.), 2017

Odd Number / 16:30-17:30, Exhibition Immune response to bacteial
Goro Matsuzaki Yuki Kinjo
infections
Even Number / 17:30-18:30 Hall

100320 1-I-W18-8-O/P

Presentation: 7min,
Discussion: 3min

Makoto Kuwahara

Department of Immunology, Graduate School of
The transcriptional repressor Bach2 regulates differentiation of pathogenic Th2 cells
Medicine, Ehime University, Ehime, Japan

Dec. 12(Tue.), 201714:55-16:15

100321 1-A-W1-8-P

Poster Presentation

Tomohiro Tamachi Graduate School of Medicine, Chiba University,

100322 1-B-W3-6-O/P

Presentation: 7min,
Discussion: 2min

Kohsuke Tsuchiya

Cancer Research Institute, Kanazawa University, Caspase-1 serves as an apoptosis-initiating caspase in the absence of Gasdermin D
Kanazawa, Japan(GSDMD)

Dec. 12(Tue.), 201713:20-14:40

Room B

Endogenous innate immunity
and inflammation-1

Tatsuya Saitoh Takuya Uehata

100323 3-F-W37-1-O/P

Presentation: 7min,
Discussion: 2min

Hiroe Tetsu

Laboratory for innate Immune Systems, RIKEN,
IMS, Japan

Role of group 2 innate lymphoid cells in the skinDec. 14(Thu.), 201714:25-15:45

Room F

Mucosal-Skin Immunity-3

Eiji Umemoto

Jun Kunisawa

100324 1-G-W13-5-P

Poster Presentation

Yoshikazu Hayashi Sciences, Kumamoto University, Kumamoto,<strong>Impact of inflammatory stress on early hematopoiesis</strong>

Dec. 12(Tue.), 2017

Odd Number / 16:30-17:30, Exhibition Hematopoiesis and immune
environments
Even Number / 17:30-18:30 Hall

TakashiNagasawa

HitoshiTakizawa

100325 1-B-W4-3-O/P

Presentation: 7min,
Discussion: 2min

Akiko Ishitani

14:55-16:15

Room B

centered on the inflammatory response.</em>

Dec. 12(Tue.), 2017

Endogenous innate immunity
and inflammation-2

Osamu
Takeuchi

SachikoTakamura(Akashi)

100326 3-F-W36-1-O/P

Presentation: 7min,
Discussion: 3min

Akira Nakajima

Center for Innovation in Immunoregulative
Technology and Therapeutics, Graduate Schoolof Medicine, Kyoto University<strong>Mucus-associated functional factors in Bacteroidetes promotes interphylum</strong><strong> symbiosis and colonic homeostasis</strong>

Dec. 14(Thu.), 201712:50-14:10

Room F

Mucosal-Skin Immunity-2

Koji Hase

Gyohei Egawa

100327 2-C-W21-7-O/P

Presentation: 10min,
Discussion: 3minNgoc M Pham

Department of Surgery, Shiga University of
Medical Science, Otsu, Japan

Co-stimulation via OX40 signal <em>in vitro</em> to generate tumor antigen-specific CTLs
for adoptive cell transfer therapy

Dec. 13
14:25-15:45(Wed.), 2017

Room C

Cell therapy

Hiroaki Ikeda

Koji Tamada

100328 2-C-W21-6-O/P

Presentation: 10min,
Discussion: 3min

Satomi Okada

Department of Oncology, Nagasaki University
Graduate School of Biomedical Sciences,
Nagasaki, Japan

Development of TCR gene therapy with allogeneic &ldquo;Stealth T cells&rdquo; deficientin endogenous TCR and HLA class I molecules

Dec. 13
14:25-15:45(Wed.), 2017

Room C

Cell therapy

Hiroaki Ikeda

Koji Tamada

Department of Medical Microbiology, Mycology

100329 1-E-W10-10-P

Poster Presentation

Kotone Kawamura and Immunology, Tohoku University Graduate

Activation of Dectin-2-mediated signaling by cryptococcal capsular polysaccharides:
Comparison between <em>Cryptococcus neoformans</em> and <em>C. gattii</em>

Dec. 12(Tue.), 2017

Odd Number / 16:30-17:30, Exhibition Immune response to
mycobacteial and fungal
Even Number / 17:30-18:30 Hall
infections

Kazuyoshi
Kawakami

Hiromitsu Hara

100330 3-H-W41-13-O/P

Presentation: 7min,
Discussion: 3min

Yosuke Kurashima Medical Science, The University of Tokyo, Tokyo, fibrogenic machinery in kidney fibrosis</strong>

Dec. 14(Thu.), 201714:25-15:45

Room H

Tissue-specific immune
diseases III

Keishi Fujio

MotomuHashimotoPresentation: 7min,
Discussion: 4min

Natsumoto Bunki

Department of Allergy and Rheumatology,
Graduate School of Medicine, The University ofTokyo, Japan

Pathophysiological analysis of systemic lupus erythematosus (SLE) using patient-derived
induced pluripotent stem cells

Dec. 14(Thu.), 201712:50-14:10

Room G

Systemic autoimmune
disease (2)Yoshiya Tanaka

Masayuki
NishidePoster Presentation

Yasumitsu
Nishimura

Department of Hygiene, Kawasaki Medical
SchoolSecretory factors produced by immune cells upon exposure to asbestos facilitate
proliferation of mesothelial cells

Dec. 14(Thu.), 2017

Odd Number / 16:00-17:00, Exhibition (Immunosuppression andmodulation in tumor
Even Number / 17:00-18:00 Hall

Toshihiko
Torigoe

Yoshihiro
Hayakawa

Dec. 12(Tue.), 2017

Odd Number / 16:30-17:30, Exhibition
Helper T cells
Even Number / 17:30-18:30 Hall

Masakatsu
YAMASHITA

Motoko Y.
KIMURA

Dec. 14(Thu.), 201712:50-14:10

Innate Lymphocyte-1 (NKT,
MAIT, gdT, NK)

Kensuke
ShibataKazuyaIWABUCHI

Dec. 12(Tue.), 2017

Odd Number / 16:30-17:30, Exhibition Immune responses in cacer
immunotherapy
Even Number / 17:30-18:30 Hall

Toshihiko
Torigoe

Kenichiro Seino

Hematopoiesis and immune
environments

Department of Allergy and Clinical Immunology,
Chiba, Japan

A20 (<em>Tnfaip3</em>) expressed in T cells suppresses Th2 cell-mediated allergic airway Dec. 12
inflammation in mice
(Tue.), 2017

International Research Center for Medical

100331 3-G-W38-4-O/P

Japan<em>The three faces of F: HLA-F as a ligand for KIRs, a cofactor in antigen presentation,
Nara Medical University, Kashihara, Nara, Japan and a receptor on B cells and monocytes, combined in an immunoregulatory capacity

School of Medicine, Miyagi, japan

Division of Mucosal Immunology, Department of<strong>Mesenchymal-myeloid cell interactions in renal microenvironment for pathological
Microbiology and Immunology, The Institute ofJapan

Room I

Helper T cells

Odd Number / 16:30-17:30, Exhibition Allergy-1 : Lower airway
allergic inflammation
Even Number / 17:30-18:30 Hall

Masakatsu
YAMASHITA

Motoko Y.
KIMURA

Kenji Izuhara

Koubun Yasuda

Tumor immunology-2

100332 3-D-W33-16-P

immunity)

100333 1-I-W18-15-P

Poster Presentation

Akiho Oniyama

Immunological analysis of the mechanism for higher virulence of <em>Cryptococcus
Medical Microbiology, Mycology and
Immunology, Tohoku University Graduate School gattii</em> infection using a transgenic mouse expressing T cell antigen receptor for 98
of Medicine, Miyagi, JapankDa mannoprotein

100334 3-B-W28-1-O/P

Presentation: 11min,
Discussion: 2min

Shinya Hatano

Division of Host Defense, Medical Institute of
Bioregulation, Kyushu University, Fukuoka,
Japan.

100335 1-F-W12-11-P

Poster Presentation

Kaori Denda-Nagai Center, Juntendo University Graduate School of between C57BL/6 mice and MUC1 transgenic mice

100336 1-G-W13-10-O/P

Presentation: 6min,
Discussion: 2min

Masashi
Kanayama

Department of Immunology, Duke University
School of Medicine, Durham, North Carolina,
USA.

Balancing population sizes of myeloid and lymphoid cells by osteopontin isoforms

Dec. 12(Tue.), 201713:20-14:40

TakashiNagasawa

HitoshiTakizawa

100337 3-D-W32-3-P

Poster Presentation

Taro Kikuchi

Department of Pathology, Sapporo Medical
University, Sapporo, JapanCTL responses against cancer with an MHC class I antigen-processing defectDec. 14(Thu.), 2017

Odd Number / 16:00-17:00, Exhibition Tumor immunology-1 (Tumor Yutaka
antigens, antigen presenting
Even Number / 17:00-18:00 Hall
Kawakami
cells, anti-tumor T cells)

Hirokazu
Matsushita

100338 3-F-W36-2-P

Poster Presentation

Junko Nishio

Institute of Industrial Science, The University ofTokyo, Tokyo, Japan

Surfactant protein D directly binds to gut bacteria and regulates microbiota composition forintestinal homeostasis

Dec. 14(Thu.), 2017

Odd Number / 16:00-17:00, Exhibition
Mucosal-Skin Immunity-2
Even Number / 17:00-18:00 Hall

Koji Hase

Gyohei Egawa

100339 1-A-W1-18-P

Poster Presentation

Shigeki Katoh

Department of Respiratory Medicine, Kawasaki
Medical School, Okayama, Japan

Possible role of IL-25 in eosinophilic lung inflammation in patients with eosinophilic
pneumonia

Dec. 12(Tue.), 2017

Odd Number / 16:30-17:30, Exhibition Allergy-1 : Lower airway
allergic inflammation
Even Number / 17:30-18:30 Hall

Kenji Izuhara

Koubun Yasuda

Division of Glycobiologics, Intractable Research

Development of new monoclonal antibody specific for murine V&gamma;6 chain

Difference in humoral immune response after immunization with glycosylated MUC1

Medicine, Tokyo, Japan

15 / 30

Room B

Room GThe 46th Annual Meeting of The Japanese Society for Immunology
Submission ID

Program No.

Oral Presentation Time

1st Author

Submission ID orderAffiliation

Title

Date

Time

Venue

Session Title

Room E

Immune response to bacteial
infections

Chair1Chair2<strong>Integrated collaboration of intestinal microbiota induces bacterial translocation andTh17 immune response in primary sclerosing cholangitis</strong>

Dec. 12(Tue.), 201713:20-14:40

Dec. 14(Thu.), 2017

Odd Number / 16:00-17:00, Exhibition Dendritic cells andTsuneyasu
Macrophages-3: Inflammatory
Even Number / 17:00-18:00 Hall
KaishoResponses

Rikinari
Hanayama

13:20-14:40

Mitsuru
Matsumoto

Daisuke
Kamimura

100340 1-E-W9-11-O/P

Presentation: 7min,
Discussion: 3min

Nobuhiro
Nakamoto

Keio University School of Medicine, Tokyo,
Japan

100341 3-C-W31-16-P

Poster Presentation

HiroyukiNakashima

Immunology and Microbiology, National Defense
Liver sinusoidal endothelial cells and resident Kupffer cells are involved in cholesterol
Medical College, 3-2 Namiki Tokorozawa
metabolism in mice
Saitama, Japan

100342 1-C-W5-5-O/P

Presentation: 7min,
Discussion: 3min

Fumihiro
Yanagimura

Department of Neurology, Brain ResearchInstitute, Niigata University, Niigata, Japan

Differential dynamics of mucosal-associated invariant T cells in the blood and the CNS
lesions of patients with neuromyelitis optica

Dec. 12(Tue.), 2017

100343 2-H-W24-5-P

Poster Presentation

Kenji Ishiwata

Department of Tropical Medicine, The Jikei
University School of Medicine, Tokyo, JapanT cell-dependent long-lasting blockade of mucosal penetration by infective larvae of amurine gastrointestinal nematodeDec. 13
16:00-17:00(Wed.), 2017

Exhibition Immune response to parasite Yoichi
infections
Hall
Maekawa

Masahiro
Yamamoto

100344 3-F-W36-3-O/P

Presentation: 7min,
Discussion: 3minEiji Miyauchi

Laboratory for Intestinal Ecosystem, IMS,RIKEN, Yokohama, Japan

Mimicry peptides from gut commensals stimulate myelin-specific T cells and exacerbate
experimental autoimmune encephalomyelitis

Dec. 14(Thu.), 201712:50-14:10

Room F

Gyohei Egawa

100345 1-F-W11-1-P

Poster Presentation

Matsuoka Shuji

Department of Patology and Oncology Juntendo
Anapocosis: Direct cell death of lymphoma cells induced by mAbs.
University School of Medicine

Dec. 12(Tue.), 2017

Odd Number / 16:30-17:30, Exhibition Combination cancer
Hiroyoshi
immunothrapy -beyond
Even Number / 17:30-18:30 Hall
immune checkpoint inhibitors- Nishikawa

Yoshihiro
Hayakawa

100346 1-D-W8-3-O/P

Presentation: 6min,
Discussion: 2.5min

Chengcheng Zou

Center for AIDS research, Kumamoto University,<strong>Conserved epitope-specific CTLs controlling HIV-1 replication</strong>
Kumamoto, Japan

Dec. 12(Tue.), 201714:55-16:15

Room D

Virus infection-2

Takashi Fujita

HiroyukiOshiumi100347 1-H-W15-1-O/P

Presentation: 6min,
Discussion: 2min

Kentaro Asayama

Dept of Immunology

Dec. 12(Tue.), 201713:20-14:40

Room H

Cytokines and chemokines-1

Masaaki
Murakami

Akihiro Kimura

100348 2-B-W20-10-O/P

Presentation: 7min,
Discussion: 3min

Masahiro
Nakashima

Immunology and Microbiology, National Defense Repeated administrations of &alpha;-galactosylceramide slow the progression of lupus
Medical College, Tokorozawa, Japannephritis in BWF1 mice

Dec. 13
14:25-15:45(Wed.), 2017

Room B

Systemic autoimmune
disease (1)Hitoshi
Kohsaka

Shinsuke
Yasuda100349 3-H-W41-2-P

Poster Presentation

Zhang Baoluo

Laboratory of Pharmacotherapy of Life-Style
Related Diseases, Tohoku University

Role of histamine in IL-17 expression in Imiquimod-induced psoriasis-like inflammation
model

Dec. 14(Thu.), 2017

Odd Number / 16:00-17:00, Exhibition Tissue-specific immune
diseases III
Even Number / 17:00-18:00 Hall

Keishi Fujio

MotomuHashimoto

100350 1-F-W12-5-P

Poster Presentation

Erica YADA

Department of Cancer Immunotherapy,
Kanagawa Cancer Center Research Institute,
Kanagawa, Japan

Next-generation sequencing analysis of gemcitabine (GEM) resistant mechanism using
patient-derived xenograft (PDX) model in pancreatic cancer

Dec. 12(Tue.), 2017

Odd Number / 16:30-17:30, Exhibition Immune responses in cacer
immunotherapy
Even Number / 17:30-18:30 Hall

Toshihiko
Torigoe

Kenichiro Seino

100351 2-C-W21-13-P

Poster Presentation

Kento Fujiwara

Project for Vaccine and Immune Regulation,
Graduate School of Pharmaceutical Sciences,
Osaka University

Immunological quality and performance of tumor vessel-targeting CAR-T cells prepared bymRNA-EP for clinical researchDec. 13
16:00-17:00(Wed.), 2017

Exhibition
Cell therapy
Hall

Hiroaki Ikeda

Koji Tamada

100352 1-F-W12-10-O/P

Presentation: 10min,
Discussion: 3min

Yoshino Tanaka

Division of Immunobiology, Institute for Genetic
Medicine, Hokkaido University, Sapporo, Japan

Dying but not dead cancer cells exert the effect of cell-based cancer vaccine

Dec. 12(Tue.), 201714:55-16:15

Room F

Immune responses in cacer
immunotherapy

Toshihiko
Torigoe

Kenichiro Seino

100353 1-B-W4-4-O/P

Presentation: 7min,
Discussion: 2min

Toshiaki Totoki

Dept. of Immunology<strong>Overexpression of protein S exacerbates carbon tetrachloride-induced liver injury
and fibrosis</strong>

Dec. 12(Tue.), 201714:55-16:15

Room B

Endogenous innate immunity
and inflammation-2

Osamu
Takeuchi

SachikoTakamura(Akashi)100354 3-A-W26-6-P

Poster Presentation

Hirotaka Kuwata

School of dentistry, Showa University, Tokyo,
Japan

Microarray and gene co-expression analysis reveals that melatonin attenuates immune
responses and modulates actin rearrangement in macrophages.

Dec. 14(Thu.), 2017

Odd Number / 16:00-17:00, Exhibition Tolerance and immune
suppression -1
Even Number / 17:00-18:00 Hall

Taku Okazaki

Shunsuke
Chikuma

100355 1-B-W4-15-P

Poster Presentation

Yasuharu
Watanabe

Department of Immunobiology andPharmacological Genetics, Graduate School of
Medicine and Pharmaceutical Science for
Research, University of Toyama, Toyama,Japan<strong>The interaction of neutrophils with adipocytes plays a key role in the infiltration ofmacrophage into the adipose tissue</strong>

Dec. 12(Tue.), 2017

Odd Number / 16:30-17:30, Exhibition Endogenous innate immunity Osamu
and inflammation-2
Even Number / 17:30-18:30 Hall
Takeuchi100356 1-A-W1-11-O/P

Presentation: 7min,
Discussion: 3min

Kentaro Fujiwara

Dept. of Immunology<strong>M1 macrophages mediate attenuation of bronchial asthma by matrixmetalloproteinase-2</strong>

Dec. 12(Tue.), 201713:20-14:40

100357 1-D-W7-13-P

Poster Presentation

Yoshiko Murakata<strong>Studies of incomplete control of Epstein-Barr virus infection by using cynomolgus
Tsukuba Primate Research Center, National
Institute of Biomedical Innovation, Ibaraki, Japan macaques model.</strong>

Dec. 12(Tue.), 2017

100358 1-F-W12-9-P

Poster Presentation

Shunsuke Takese

Department of Pharmacokinetics andBiopharmaceutics, Institute of Biomedical
Sciences, Tokushima University, Tokushima,Japan

100359 1-E-W9-8-P

Poster Presentation

Matsui Katsuhiko100360 3-H-W40-13-P

Poster Presentation

100361 2-H-W24-3-P

Poster Presentation<strong>A novel mouse model of spontaneous lung cancer caused by lung TGF-&beta;1overexpression</strong>Room C

Mucosal-Skin Immunity-2

Allergy-1 : Lower airway
allergic inflammation

Koji Hase

SachikoTakamura(Akashi)Kenji Izuhara

Koubun Yasuda

Odd Number / 16:30-17:30, Exhibition
Virus infection-1
Even Number / 17:30-18:30 Hall

Taro Kawai

Mitsutoshi
Yoneyama

Dec. 12(Tue.), 2017

Odd Number / 16:30-17:30, Exhibition Immune responses in cacer
immunotherapy
Even Number / 17:30-18:30 Hall

Toshihiko
Torigoe

Kenichiro Seino

Department of Microbial Science and Host<strong>Mast cells stimulated with peptidoglycan from <em>Staphylococcus aureus</em>
Defense, Meiji Pharmaceutical University, Tokyo,
enhance the development of Th1 cells</strong>Japan

Dec. 12(Tue.), 2017

Odd Number / 16:30-17:30, Exhibition Immune response to bacteial
Goro Matsuzaki Yuki Kinjo
infections
Even Number / 17:30-18:30 Hall

Shotaro Nakajima

Dept. Immunology, Univ. Yamanashi,
Yamanashi, Japan

Resveratrol inhibits IL-33-mediated mast cell activation

Dec. 14(Thu.), 2017

Odd Number / 16:00-17:00, Exhibition
Granulocyte & Mast cells
Even Number / 17:00-18:00 Hall

Takeshi Ono

Department of Global Infectious Diseases andTropical Medicine, National Defense Medical
CollegeCD8<sup>+</sup> T cell immune responses during the <em>Plasmodium berghei</em>
ANKA blood stage infection

Dec. 13
16:00-17:00(Wed.), 2017

The combined effect of liposomal oxaliplatin with cancer vaccine on anticancer therapy.

16 / 30

Room A

Tissue-specific immune
diseases I

Goro Matsuzaki Yuki Kinjo

Atsuhito Nakao

Exhibition Immune response to parasite Yoichi
infections
Hall
Maekawa

YosukeKurashima
Masahiro
Yamamoto

The 46th Annual Meeting of The Japanese Society for Immunology
Submission ID

Program No.

Oral Presentation Time

Submission ID order

1st Author

Affiliation

Title

Date

Time

Venue

Session Title

Chair1Chair2

12:50-14:10

Room D

Tumor immunology-1 (Tumor
antigens, antigen presenting
cells, anti-tumor T cells)

YutakaKawakami

Hirokazu
Matsushita

Room H

Granulocyte & Mast cells

Atsuhito Nakao

YosukeKurashima

Koji Hase

Gyohei Egawa

100362 3-D-W32-4-O/P

Presentation: 7min,
Discussion: 3min

Yoh Ohnuki

Department of Immunology, Graduate School of
Medicine and Pharmaceutical Sciences,
The model of antigen detection system using yeast surface display library
University of Toyama, 2630 Sugitani, Toyama
930-0194, Japan

100363 3-H-W40-1-O/P

Presentation: 7min,
Discussion: 3min

Jing Wang

Institute of Enzyme Research, Tokushima
University, Tokushima, Japan

Tracking the fate of neutrophils in sterile injury using photoactivation and intravital imaging

Dec. 14(Thu.), 201712:50-14:10

100364 3-F-W36-15-P

Poster Presentation

Noriko Sato

Dept. of Plastic and Reconstructive surgery,
Tohoku Univ.

Effect of Mincle deficiency on the wound healing process in skinDec. 14(Thu.), 2017

Odd Number / 16:00-17:00, Exhibition
Mucosal-Skin Immunity-2
Even Number / 17:00-18:00 Hall100365 1-F-W12-1-O/P

Presentation: 10min,
Discussion: 3min

Hirohito Ishigaki

Department of Pathology, Shiga University of
Medical Science, Otsu, Japan,<strong>The hemoperfusion column removing LAP positive cells activates the tumorspecific immunity in a cynomolgus monkey</strong>

Dec. 12(Tue.), 201714:55-16:15

Room F

Immune responses in cacer
immunotherapy

Toshihiko
Torigoe

Kenichiro Seino

100366 2-G-W23-5-O/P

Presentation: 10min,
Discussion: 3min

Sumika Toyama

Institute for Environmental and Gender Specific
Medicine, Juntendo University Graduate Schoolof Medicine, Chiba, Japan

Regulatory T cells control skin inflammation in atopic dermatitis model mouse

Dec. 13
14:25-15:45(Wed.), 2017

Room G

Allergy-3 : Allergic dermatitis,
food allergy and allergic
conjunctivitis

Kenji Izuhara

Tomohiro
Yoshimoto

100367 1-G-W13-17-O/P

Presentation: 6min,
Discussion: 2min

Kazuki Sato

Department of Immunology, Faculty of Medicine, Marginal reticular cells act as a non-professional phagocyte for clearance of apoptotic B
University of Tsukuba, Ibaraki, Japan
cells

Dec. 12(Tue.), 201713:20-14:40

Room G

Hematopoiesis and immune
environments

TakashiNagasawa

HitoshiTakizawa

100368 2-I-W25-2-O/P

Presentation: 7min,
Discussion: 3min

Alessandro Nasti

System Biology, Kanazawa University,
Kanazawa, Japan<strong>The CD45<sup>+</sup> subset in murine uncultured adipose tissue-derived
stromal cells features immune-inhibitory M2 macrophage-like cells</strong><strong>
contributable for </strong><strong>therapeutics </strong><strong>of</strong><strong>acute h

Dec. 13
14:25-15:45(Wed.), 2017

Room I

Dendritic cells andMacrophages-1: Organspecific Immune Tolerance

Satoshi Ishido

Kenichi Asano

100369 3-C-W30-10-O/P

Presentation: 7min,
Discussion: 3min

Naoki Matsumoto

Graduate School of Frontier Sciences, theUniversity of Tokyo, Chiba, Japan

Co-expression of DCIR3 and DCIR4 on monocytes

Dec. 14(Thu.), 201712:50-14:10

Room C

Dendritic cells andTomohiko
Macrophages-2: Development
Tamuraand Recognition

100370 3-H-W40-14-O/P

Presentation: 7min,
Discussion: 3min

Wakabayashi
Seiichiro

Dermatology, Chiba University, Chiba, Japan

Homeostasis of peripheral macrophages are controlled by mast cells <em>via</em> newly
identified c-Kit<sup>+</sup>CD11b<sup>+</sup> tissue-resident macrophage progenitor
cells

Dec. 14(Thu.), 201712:50-14:10

Room H

Granulocyte & Mast cells

100371 1-F-W11-8-O/P

Presentation: 9min,
Discussion: 2min

Alok Kumar

Department of Immunology and Genomic
Medicine, Graduate School of Medicine, Kyoto
University, Kyoto, Japan<strong>Indicators of mitochondrial activation in T cells could be a biomarker to predict the
PD-1 blockade therapeutic efficacy.</strong>

Dec. 12(Tue.), 201713:20-14:40

Room F

Combination cancer
Hiroyoshi
immunothrapy -beyond
immune checkpoint inhibitors- Nishikawa

100372 1-E-W9-1-O/P

Presentation: 7min,
Discussion: 3min

TakayukiMatsumura

Department of Immunology, National Institute of <strong>Balance of pro- and anti-inflammatory cytokines in immature myeloid cells involved
Infectious Diseases, Tokyo, Japan
in outcome of severe invasive group A <em>Streptococcus</em> infections</strong>

Dec. 12(Tue.), 201713:20-14:40

Room E

Immune response to bacteial
infections

100373 1-F-W11-6-P

Poster Presentation

Shota Kajiyama

Kobayashi Pharmaceutical Co., Ltd., Osaka,Japan

Dec. 12(Tue.), 2017

Odd Number / 16:30-17:30, Exhibition Combination cancer
Hiroyoshi
immunothrapy -beyond
Even Number / 17:30-18:30 Hall
immune checkpoint inhibitors- Nishikawa

100374 3-E-W35-8-O/P

Presentation: 7min,
Discussion: 3min

Katsuki Usami

International Education and Research Center for
Important role of the immunological network between large intestine and mammary gland in
Food and Agricultural Immunology, Graduate
School of Agricultural Science, Tohoku
breastfeeding
University, Miyagi, Japan

Dec. 14(Thu.), 201714:25-15:45

Room E

Germinal center reaction andplasma cells

100375 1-F-W11-7-O/P

Presentation: 9min,
Discussion: 2min

Nobuo Tsukamoto Advanced Medical Research, Keio University

Dec. 12(Tue.), 201713:20-14:40

Room F

Combination cancer
Hiroyoshi
immunothrapy -beyond
immune checkpoint inhibitors- Nishikawa

100376 1-I-W18-13-P

Poster Presentation

Shojiro Ikezaki

A novel alternative splicing of T-cell signaling molecule modulates TCR-mediated responses
Section of Infection Biology, Department of
Functional Bioscience, Fukuoka Dental Collage. in Th2 cells

Dec. 12(Tue.), 2017

Odd Number / 16:30-17:30, Exhibition
Helper T cells
Even Number / 17:30-18:30 Hall

100377 2-F-W22-6-P

Poster Presentation

Haruki Katsumata

Dept of Urology, Tokyo Women’s Medical Univ,
Tokyo, Japan.

100378 1-E-W10-9-P

Poster Presentation

Yuki KITAI<strong>Involvement of Dectin-2 in the recognition and phagocytosis ofMedical Microbiology, Mycology andimmunology, Tohoku University Graduate School </strong><em><strong>Cryptococcus neoformans </strong></em><strong>by dendriticof Medicine
cells</strong>

Dec. 12(Tue.), 2017

Odd Number / 16:30-17:30, Exhibition Immune response to
mycobacteial and fungal
Even Number / 17:30-18:30 Hall
infections

100379 1-B-W3-12-P

Poster Presentation

Rina Sugimoto

Department of Cell Biological Science, Graduate
School of Life Science, Hokkaido University,
Evaluation system for receptor expression and function in the intestinal stem cell niche
Sapporo, Japan

Dec. 12(Tue.), 2017

Odd Number / 16:30-17:30, Exhibition Endogenous innate immunity
Tatsuya Saitoh Takuya Uehata
and inflammation-1
Even Number / 17:30-18:30 Hall

Asuka Miyamoto

Department of Molecular Life Science, Tokai
University School of Medicine, Isehara,
Kanagawa, Japan

Dec. 14(Thu.), 2017

Odd Number / 16:00-17:00, Exhibition (Immunosuppression andmodulation in tumor
Even Number / 17:00-18:00 Hall

Division of cellular Signaling, Institute for
School of Medicine, Tokyo, Japan

Investigation of the effect of a combination of immune checkpoint inhibitor and Lentinula
Edodes Mycelia (L.E.M.) extract on antitumor response in CT26 colon carcinoma-bearing
mice.

Berberine augments tumor antigen specific T cells <em>in vivo</em> through metabolic
remodeling in CD8<sup>+</sup> T cells in tumors and lymph nodes

In Vitro Stimulation with &alpha;-galactosylceramide Expands
CD4<sup>+</sup>CD25<sup>+</sup>Foxp3<sup>&minus;</sup> Regulatory T Cell
Precursors in Murine Thymocytes

Dec. 14(Thu.), 2017

Dec. 13
16:00-17:00(Wed.), 2017

Exhibition T cell-1: T cell development
and repertoire selection
Hall

Atsuhito Nakao

Masafumi
Nakayama
YosukeKurashima
Yoshihiro
Hayakawa

Goro Matsuzaki Yuki Kinjo

Masaki Hikida

Yoshihiro
Hayakawa
Wataru Ise
Yoshihiro
Hayakawa

Masakatsu
YAMASHITA

Motoko Y.
KIMURA

TaishinAkiyamaTakeshi Nitta

Kazuyoshi
Kawakami

Hiromitsu Hara

Tumor immunology-2

100380 3-D-W33-11-P

Poster Presentation

Production of specific IgG against HER2 peptide is decreased in NOG-IL4-Tg micetransplanted with breast cancer patients PBMC

Toshihiko
Torigoe

Yoshihiro
Hayakawa

Kenji
Kabashima

Yoshiyuki Goto

immunity)

100381 2-A-W19-3-O/P

Presentation: 7min,
Discussion: 3min

Daisuke Takahashi Japan

100382 1-B-W3-15-P

Poster Presentation

Takumi Adachi

Department of Immunology, Hyogo College ofMedicine, Nishinomiya, Hyogo, Japan

100383 1-E-W9-4-O/P

Presentation: 7min,
Discussion: 3min

Rin Yokoyama

Medical Microbiology, Mycology and<strong>Dectin-2-mediated signaling triggered by serotype 3 <em>Streptococcus
Immunology, Tohoku University Graduate School
pneumoniae </em>and its contribution to host immune response</strong>of Medicine, Miyagi, Japan

Keio University Faculty of Pharmacy, Tokyo,

Microbial fermentation product butyrate Ameliorates Autoimmune Arthritis.

Dec. 13
14:25-15:45(Wed.), 2017

Purification and characterization of a unique DAMP of a potent inducer of IL-33 expression
in non-hematopoietic cells

Dec. 12(Tue.), 2017

Odd Number / 16:30-17:30, Exhibition Endogenous innate immunity
Tatsuya Saitoh Takuya Uehata
and inflammation-1
Even Number / 17:30-18:30 Hall

Dec. 12(Tue.), 201713:20-14:40

17 / 30

Room A

Room E

Mucosal-Skin Immunity-1

Immune response to bacteial
infections

Goro Matsuzaki Yuki Kinjo

The 46th Annual Meeting of The Japanese Society for Immunology
Submission ID

Program No.

Oral Presentation Time

Submission ID order

1st Author

Affiliation

Title

Date

Analysis of follicular helper T cells in a mouse model for Sj&ouml;gren&rsquo;s syndrome

Dec. 12(Tue.), 2017

Anti-diabetic effect of matrix metalloproteinase-2 and its correlation with protein S indiabetes

Time

Venue

Session Title

14:55-16:15

Room C

Tissue-specific immune
diseases II

NaozumiIshimaru

Hiroto Tsuboi

Dec. 14(Thu.), 201714:25-15:45

Room H

Tissue-specific immune
diseases III

Keishi Fujio

MotomuHashimoto

Room EB cell development andfunction

Yoshiteru
Sasaki

Reiko Shinkura

Toshihiko
Torigoe

Yoshihiro
Hayakawa

100384 1-C-W6-7-O/P

Presentation: 7min,
Discussion: 3min

Kunihiro Otsuka

Department of Oral Molecular Pathology,
Institute of Biomedical Science, Tokushima
University Graduate School, Tokushima, Japan

100385 3-H-W41-9-O/P

Presentation: 7min,
Discussion: 3min

Kota Nishihama

Mie University Graduated School of Medicine,
Diabetes, Metabolism and Endocrinology, Tsu,Japan

100386 3-E-W34-3-O/P

Presentation: 7min,
Discussion: 3min

Hitomi Sakatani

Nara Institute of Science and Technology, Nara,
Novel compounds that induce specifically class switching to IgAJapanDec. 14(Thu.), 201712:50-14:10

100387 3-D-W33-7-P

Poster Presentation

Mikako Nishida

Department of Immunology, Graduate School of
Medicine, Dentistry and Pharmaceutical
Anti-oxidative stress response is involved in Metformin-induced anti-tumor immunity
Sciences, Okayama University, Okayama, Japan

Dec. 14(Thu.), 2017

Odd Number / 16:00-17:00, Exhibition (Immunosuppression andmodulation in tumor
Even Number / 17:00-18:00 Hall

Chair1Chair2Tumor immunology-2

immunity)

100388 3-F-W37-12-O/P

Presentation: 7min,
Discussion: 2min

Motoyoshi Nagai

Graduate School of Pharmaceutical Science,
Keio University, Tokyo, Japan

Nutritional signals are essential for the regulation of cell dynamics and mucosal immune
response in GALT

Dec. 14(Thu.), 201714:25-15:45

Room F

Mucosal-Skin Immunity-3

Eiji Umemoto

Jun Kunisawa

100389 3-A-W27-7-O/P

Presentation: 10min,
Discussion: 3min

Yoshiaki Yasumizu Japan

Faculty of Medicine, Osaka University, Osaka,Significance of the regulatory T cell-specific epigenetics in autoimmune diseasesusceptibility

Dec. 14(Thu.), 201714:25-15:45

Room A

Tolerance and immune
suppression -2

Naganari
OhkuraTakashi Sekiya

100390 3-H-W40-2-P

Poster Presentation

Shin Morisawa

Department of Immunology, Kitasato University
Graduate School of Medical Sciences,
Sagamihara, Japan.

Quantitative analysis of Neutrophil extracellular traps (NETs) in lupus prone mouse usingnovel methods

Dec. 14(Thu.), 2017

Odd Number / 16:00-17:00, Exhibition
Granulocyte & Mast cells
Even Number / 17:00-18:00 Hall

Atsuhito Nakao

YosukeKurashima100391 3-I-W42-6-O/P

Presentation: 7min,
Discussion: 3min

Takayuki Imanishi

RIKEN Center for Integrative Medical Sciences(IMS) Laboratory for Cell Signaling, Yokohama,Japan

TCR-signals control STING-mediated type 1 IFN responses in T cells

Dec. 14(Thu.), 201712:50-14:10

Room IT cell-2 : T cell signaling

SatoshiMatsudaTadashiYokosuka100392 3-B-W28-12-O/P

Presentation: 11min,
Discussion: 2min

Asako Chiba

Department of Immunology, Juntendo University,
MAIT cells exacerbate the disease course of oxazolone colitis.
Tokyo, Japan

Dec. 14(Thu.), 201712:50-14:10

Room B

Innate Lymphocyte-1 (NKT,
MAIT, gdT, NK)

Kensuke
ShibataKazuyaIWABUCHI

100393 1-F-W11-12-O/P

Presentation: 9min,
Discussion: 2min

Nanumi Han

Division of Immunobiology, Institute for Genetic
Medicine, Hokkaido University, Sapporo, Japan<strong>Identification of factors that affect myeloid cells in immunotherapeutic-resistanttumors</strong>

Dec. 12(Tue.), 201713:20-14:40

Room F

Combination cancer
Hiroyoshi
immunothrapy -beyond
immune checkpoint inhibitors- Nishikawa

100394 2-G-W23-18-P

Poster Presentation

Hee Soon Shin

Korea Food Research Institute, Sungnam-si,
Korea

Baicalein induces CD4+Foxp3+ T cells and enhances intestinal barrier function in a mousemodel of food allergy

Dec. 13
16:00-17:00(Wed.), 2017

Exhibition Allergy-3 : Allergic dermatitis,
food allergy and allergic
Kenji IzuharaHallconjunctivitis

100395 3-B-W28-4-O/P

Presentation: 11min,
Discussion: 2min

Eri Ishikawa

Department of Molecular Immunology, ResearchInstitute for Microbial Diseases, Osaka
A critical role of protein kinase D in NKT cell development
University, Osaka, Japan

Dec. 14(Thu.), 201712:50-14:10

Room B

Department of Immunology, Graduate School of100396 3-F-W37-2-P

Poster Presentation

Weng Sheng Kong Biomedical and Health Sciences, Hiroshima

Analysis of gut and skin inflammation in the pathogenesis of atopic dermatitis

Dec. 14(Thu.), 2017

Odd Number / 16:00-17:00, Exhibition
Mucosal-Skin Immunity-3
Even Number / 17:00-18:00 Hall100397 1-H-W15-15-P

Poster Presentation

Hiroki Tanaka

World Premier Institute Immunology Frontier
Research Center (WPI-IFReC), Osaka
University, Osaka, Japan

Regnase-1 phosphorylation induced by proinflammatory cytokines controls stability of its
target mRNAs.

Dec. 12(Tue.), 2017

Odd Number / 16:30-17:30, Exhibition
Masaaki
Cytokines and chemokines-1
Even Number / 17:30-18:30 Hall
Murakami

100398 1-I-W17-17-P

Poster Presentation

Kaori Hayashi

Department of Obstetrics and Gynecology, Shiga Efficacy of spontaneous occurring endometriosis by extracorporeal circulation in
University of Medical Science, Otsu, Japancynomolgus monkey

Dec. 12(Tue.), 2017

Odd Number / 16:30-17:30, Exhibition
Human Immunology
Even Number / 17:30-18:30 Hall

Koji Yasutomo Keishi Fujio

Department of Immunology, Graduate School of100399 3-H-W41-3-P

Poster Presentation

Shoichiro Miyatake Environmental Health Sciences, Azabu

Dec. 14(Thu.), 2017

Odd Number / 16:00-17:00, Exhibition Tissue-specific immune
diseases III
Even Number / 17:00-18:00 Hall

Keishi Fujio

MotomuHashimoto

100400 2-G-W23-6-O/P

Presentation: 10min,
Discussion: 3minKazumasa
Kanemaru

Department of Immunology, Faculty of Medicine,<strong>Clec10a suppresses house dust mite-induced dermatitis</strong>
University of Tsukuba, Ibaraki, Japan

Kenji Izuhara

Tomohiro
Yoshimoto

100401 3-H-W41-10-P

Poster Presentation

Taro Yasuma

Department of Immunology, Mie University
Graduate School of Medicine

Protein S inhibits apoptosis of pancreatic &beta; cells by regulating BIRC3 expression and
AKT signaling

Dec. 14(Thu.), 2017

Odd Number / 16:00-17:00, Exhibition Tissue-specific immune
diseases III
Even Number / 17:00-18:00 Hall

Keishi Fujio

MotomuHashimoto

100402 3-C-W30-12-O/P

Presentation: 7min,
Discussion: 3min

Shojiro Haji

Department of Molecular Immunology, Division
Recognition of lipids from <em>Helicobacter pylori</em> by dendritic cell immunoactivatingof Host Defense, Research Institute for Microbial
receptor (DCAR).
Diseases, Osaka University, Osaka, Japan

Dec. 14(Thu.), 201712:50-14:10

Room C

Dendritic cells andTomohiko
Macrophages-2: Development
Tamuraand Recognition

100403 1-I-W17-18-O/P

Presentation: 7min,
Discussion: 3min

Iyoda Tomonori

RIKEN Center for Integrative Medical Sciences,
Yokohama, Japan

Dec. 12(Tue.), 201713:20-14:40

Room I

Human Immunology

Koji Yasutomo Keishi Fujio

100404 3-D-W33-3-O/P

Presentation: 7min,
Discussion: 3min

Hirotake
TsukamotoDepartment of Immunology, Graduate School of<strong>Combined blockade of IL-6 and PD-L1 signals breaks a mutual regulation of their
Medical Sciences, Kumamoto University,
immunosuppressive effects on anti-tumor immunity</strong>
Kumamoto, Japan

Dec. 14(Thu.), 201714:25-15:45

Room D

Tumor immunology-2(Immunosuppression andmodulation in tumor
immunity)Toshihiko
Torigoe

Yoshihiro
Hayakawa

100405 1-C-W5-3-O/P

Presentation: 7min,
Discussion: 3min

Youwei Lin

Department of Immunology, National Institute of Inverse vaccination by superior dominant peptide inhibit the reactivity to disease-associated
Neuroscience, National Center of Neurology and antigens and promote tissue-repair capacity in stabilized antigen-specific regulatory T cells
Psychiatry
to control of relapsing and progression of animal model of multiple

Dec. 12(Tue.), 201713:20-14:40

Room C

Tissue-specific immune
diseases I

Mitsuru
Matsumoto

Daisuke
Kamimura

University, japan

Dermatitis developed in GATA3 mutant mice

University, Kanagawa, Japan

Improvement of NK cell function against multiple myeloma cells by an adjunctive effect ofactivated invariant natural killer T (NKT) cells

18 / 30

Dec. 13
14:25-15:45(Wed.), 2017

Room G

Innate Lymphocyte-1 (NKT,
MAIT, gdT, NK)

Allergy-3 : Allergic dermatitis,
food allergy and allergic
conjunctivitis

Yoshihiro
Hayakawa
Tomohiro
YoshimotoKensuke
ShibataKazuyaIWABUCHI

Eiji Umemoto

Jun Kunisawa

Akihiro Kimura

Masafumi
Nakayama

The 46th Annual Meeting of The Japanese Society for Immunology
Submission ID

Program No.

Oral Presentation Time

1st Author

Submission ID orderAffiliation
National Center of Neurology and Psychiatry
National Institute of Neuroscience, Department
of Immunology, Tokyo, Japan

100406 3-E-W35-9-O/P

Presentation: 7min,
Discussion: 3min

Hirohiko Ono

100407 2-B-W20-5-P

Poster Presentation

Hiroyuki Nishimura Toin University of Yokohama, Yokohama Japan

100408 3-A-W26-7-P

Poster Presentation

100409 1-F-W11-11-O/P

Title

Date

Time

Venue

Session Title

Chair1Chair2

Room E

Germinal center reaction andplasma cells

Masaki Hikida

Wataru Ise

Hitoshi
Kohsaka

Shinsuke
YasudaTaku Okazaki

Shunsuke
ChikumaDysregulated B cells in Myalgic encephalomyelitis/Chronic Fatigue Syndrome

Dec. 14(Thu.), 2017

Toin Human Science and Technology Center,

Epistatic interaction between <em>fcgr2b</em> and <em>Slam</em> family genes insusceptibility to defective foreign protein-induced tolerance

Dec. 13
16:00-17:00(Wed.), 2017

Yuya Yoshida

Department of Pathological Biochemistry,
Faculty of Pharmaceutical Sciences, Setsunan
University, Osaka, Japan

Induction of immune tolerance by combination treatment with fingolimod (FTY720) plus
pathogenic antigen in a glucose-6-phosphate isomerase peptide-induced arthritis mousemodel: the fourth report

Dec. 14(Thu.), 2017

Odd Number / 16:00-17:00, Exhibition Tolerance and immune
suppression -1
Even Number / 17:00-18:00 Hall

Presentation: 9min,
Discussion: 2min

Chang-Yu Chen

Department of Molecular Preventive Medicine,
Graduate School of Medicine, The University ofTokyo, Tokyo, Japan<strong>Low-dose HMGN1 synergistically enhances anti-tumor immunity in CD4 depleting
antibody-treated mice</strong>

Dec. 12(Tue.), 201713:20-14:40

100410 3-E-W34-11-P

Poster Presentation

Ryouma Totera

Narashino, Chiba , Japan

Cultured B cells and Immune globlulin gene expression.

Dec. 14(Thu.), 2017

Odd Number / 16:00-17:00, Exhibition B cell development andfunction
Even Number / 17:00-18:00 Hall

Yoshiteru
Sasaki

Reiko Shinkura

100411 1-H-W15-3-O/P

Presentation: 6min,
Discussion: 2min

Wooseok Seo

RIKEN IMS Center for Integrative Medical
Sciences,Yokohama, Japan

Regulation of CCL5 expression by Runx complexes and two stage-specific enhancers

Dec. 12(Tue.), 201713:20-14:40

Masaaki
Murakami

Akihiro Kimura

100412 1-I-W17-4-P

Poster Presentation

Yusuke Ohno

Department of Molecular Life Science, Tokai
University School of Medicine, Isehara, Japan<strong>Pregnant humanized mouse as a model of human pregnant immunity</strong>

Dec. 12(Tue.), 2017

Odd Number / 16:30-17:30, Exhibition
Human Immunology
Even Number / 17:30-18:30 Hall

Koji Yasutomo Keishi Fujio

100413 1-I-W18-10-O/P

Presentation: 7min,
Discussion: 3min

Masaki Tajima

Laboratory of Host Defenses, NIAID, NIH,
Maryland, USA<strong>IL-10-Producing Tr2 cells Induced by mTOR/CEBP&beta; Signaling Regulate
Hyphal <em>C. albicans</em> Kidney Infection</strong>

Dec. 12(Tue.), 201714:55-16:15

Room I

Helper T cells

Masakatsu
YAMASHITA

100414 3-I-W43-17-O/P

Presentation: 7min,
Discussion: 3min

Harumichi
Iahigame

Laboratory for Tissue Dynamics, RIKEN Center
for Integrative Medical Sciences, Kanagawa,Japan<strong>Developmental plasticity of KLRG1<sup>+</sup> effector CD8<sup>+</sup> T
cells promotes protective immunity</strong>

Dec. 14(Thu.), 201714:25-15:45

Room IT cell-3 : T cell function

Harumi Suzuki Ei Wakamatsu

100415 3-H-W41-11-O/P

Presentation: 7min,
Discussion: 3minAtsuro Takeshita

Diabetes, Metabolism and Endocrinology, Mie
University Graduate School of Medicine, Tsu,
Japan

Protein S reduces the progression of diabetic nephropathy in mice

Dec. 14(Thu.), 201714:25-15:45

Room H

Tissue-specific immune
diseases III

Keishi Fujio

MotomuHashimoto

100416 3-C-W31-13-P

Poster Presentation

Natsuno Hama

Department of Biosciences, School of Science,
Kitasato University, Kanagawa, Japan

Rap1 plays central role in adhesion and migration of DCs.

Dec. 14(Thu.), 2017

Odd Number / 16:00-17:00, Exhibition Dendritic cells andTsuneyasu
Macrophages-3: Inflammatory
Even Number / 17:00-18:00 Hall
KaishoResponses

Rikinari
Hanayama

100417 3-I-W42-11-O/P

Presentation: 7min,
Discussion: 3minTsuyoshi Sato

Department of Biosciences, School of Science,
Kitasato University, kanagawa, JapanT cell specific Rap1-deficient mice develop spontaneous colitis

Dec. 14(Thu.), 201712:50-14:10

100418 3-A-W27-3-P

Poster Presentation

Yuji Kashiwakura

Department of Immunology, Dokkyo Medical
University School of Medicine, Mibu, Tochigi,
Japan

Heparin induces regulatory T cells by IL-2 production in mice

Dec. 14(Thu.), 2017

Odd Number / 16:00-17:00, Exhibition Tolerance and immune
suppression -2
Even Number / 17:00-18:00 Hall

100419 2-A-W19-10-P

Poster Presentation

Daisuke
TAKABAYASHI

Narashino, Chiba , Japan

Roles of MGL2 positive DC and Basophil on type 2 Contact Hypersensitivity model mice.

Dec. 13
16:00-17:00(Wed.), 2017

Yuetsu Tanaka

Department of Immunology, Graduate School of The importance of fixation/permeablization methods for flow cyotometric detection of human
Medicine, University of the Ryukyus, Okinawa,
FoxP3 antigen as examined using human Treg and non-Treg cell lines transformed by
Japan
HTLV-I

Dec. 14(Thu.), 2017

100420 3-D-W33-14-P

Poster Presentation

14:25-15:45

Exhibition Systemic autoimmune
disease (1)Hall

Room F

Room H

Room I

Combination cancer
Hiroyoshi
immunothrapy -beyond
immune checkpoint inhibitors- Nishikawa

Cytokines and chemokines-1

T cell-2 : T cell signaling

Exhibition
Mucosal-Skin Immunity-1
Hall

Yoshihiro
Hayakawa

Motoko Y.
KIMURA

SatoshiMatsudaTadashiYokosuka

Naganari
OhkuraTakashi Sekiya

Kenji
Kabashima

Yoshiyuki Goto

Toshihiko
Torigoe

Yoshihiro
Hayakawa

YutakaKawakami

Hirokazu
Matsushita

Tumor immunology-2

Odd Number / 16:00-17:00, Exhibition (Immunosuppression andmodulation in tumor
Even Number / 17:00-18:00 Hall
immunity)
Tumor immunology-1 (Tumor
antigens, antigen presenting
cells, anti-tumor T cells)

100421 3-D-W32-10-O/P

Presentation: 7min,
Discussion: 3min

Risa Fujii

Department of Anatomy and Embryology, Faculty<strong>MafB inhibits tumor growth through regulating</strong> <strong>Tumorof medicine, University of Tsukuba, Tsukuba,
Associated &ndash;Macrophages in spleen</strong>Japan

Dec. 14(Thu.), 201712:50-14:10

100422 1-E-W9-10-P

Poster Presentation

Hiromi Miyazaki

Division of Traumatology, Research Institute,
National Defense Medical College, Tokorozawa,
Japan

Coenzyme Q10 supplementation protects against methicillin-resistant Staphylococcus
aureus infection in burn-injured mice

Dec. 12(Tue.), 2017

Odd Number / 16:30-17:30, Exhibition Immune response to bacteial
Goro Matsuzaki Yuki Kinjo
infections
Even Number / 17:30-18:30 Hall

100423 2-F-W22-9-P

Poster Presentation

Kana Misawa

Kitasato University School of Medicine,
Sagamihara, Japan

Analyses of genes expressed in the cortical thymic epithelial cells in immuno-compromised,<em>alymphoplasia</em> mice

Dec. 13
16:00-17:00(Wed.), 2017

100424 3-A-W27-5-P

Poster Presentation

Hidefumi Kojima

Department of Immunology, Dokkyo Medical
University School of Medicine, Tochigi, Japan

Fatty acids affect regulatory T cell metabolism and function during immune responses.

Dec. 14(Thu.), 2017

100425 2-H-W24-6-P

Poster Presentation

Koubun Yasuda

Department of Immunology, Hyogo College ofMedicine

IL-33-dependent resistance of <em>Strongyloides venezuelensis</em>-experienced miceagainst <em>Nippostrongylus brasiliensis</em> infection

Dec. 13
16:00-17:00(Wed.), 2017

Exhibition Immune response to parasite Yoichi
infections
Hall
Maekawa

Masahiro
Yamamoto

100426 3-E-W35-1-O/P

Presentation: 7min,
Discussion: 3min

Katsuya Sato

Department of Molecular Pathobiochemistry,
Gifu University School of Medicine, Gifu, Japan

Analysis of cis-regulatory elements involved in the regulation of expression of<em>Aicda</em>

Dec. 14(Thu.), 201714:25-15:45

Room E

Germinal center reaction andplasma cells

Masaki Hikida

Wataru Ise

100427 3-B-W29-11-P

Poster Presentation

Daichi
KOBAYASHI

Chiba Institute of Technology, Faculty ofEngineering, Department of Life andEnvironmental Sciences. Narashino, Chiba,
Japan

The effect of ILC3 regulated by glial cells in gut in inflammatory condition.

Dec. 14(Thu.), 2017

Odd Number / 16:00-17:00, Exhibition Innate Lymphocyte-2(ILC1,2,3)
Even Number / 17:00-18:00 Hall

SusumuNAKAE

Shinichiro
SAWA

19 / 30

Room D

Exhibition T cell-1: T cell development
and repertoire selectionHall

Odd Number / 16:00-17:00, Exhibition Tolerance and immune
suppression -2
Even Number / 17:00-18:00 Hall

TaishinAkiyamaTakeshi Nitta

Naganari
OhkuraTakashi Sekiya

The 46th Annual Meeting of The Japanese Society for Immunology
Submission ID

Program No.

Oral Presentation Time

Submission ID order

1st Author

Affiliation

Title

Date

Time

Venue

Session Title

Chair1Chair2100428 3-H-W40-23-P

Poster Presentation

Toshihisa NAGAO

The Department of Immune Regulation, Tokyo
Medical and Dental University, Tokyo, Japan

Sugar modification of carrier protein confers ability on allergen to induce IgE- and basophilmediated allergic inflammation

Dec. 14(Thu.), 2017

Odd Number / 16:00-17:00, Exhibition
Granulocyte & Mast cells
Even Number / 17:00-18:00 Hall

Atsuhito Nakao

YosukeKurashima100429 3-E-W34-12-P

Poster Presentation

Ryouma KOTERA

Chiba Institute of Technology, Graduate Schoolof Engineering, Department of Life andEnvironmental Sciences, Tsudanuma, Chiba,JapanT cell dependent and independent regulation on immune globulin gene expressions in vitro
B cell differentiation

Dec. 14(Thu.), 2017

Odd Number / 16:00-17:00, Exhibition B cell development andfunction
Even Number / 17:00-18:00 Hall

Yoshiteru
Sasaki

Reiko Shinkura

100430 2-B-W20-8-P

Poster Presentation

Akira Iizuka

Department of Internal Medicine, Faculty of
Medicine, University of Tsukuba, Ibaraki, JapanThe regulatory role of Allergin-1 in autoantibody production

Dec. 13
16:00-17:00(Wed.), 2017

Exhibition Systemic autoimmune
disease (1)Hall

Hitoshi
Kohsaka

Shinsuke
Yasuda100431 1-D-W7-2-O/P

Presentation: 6min,
Discussion: 2min

Hiroshi Ueki

Division of Virology, Department of Microbiology
Visualization of immune responses to influenza virus in mouse lung by using two-photon
and Immunology, Institute of Medical Science,microscopy
University of Tokyo

Dec. 12(Tue.), 201713:20-14:40

Room D

Taro Kawai

Mitsutoshi
Yoneyama

100432 3-D-W32-17-P

Poster Presentation

Yui Ezaki

Department of Immunology,Kurume University
School of Medicine<strong>Chitinase 3-like 1</strong><strong> (CHI3L1/YKL-40)</strong><strong> induces
carcinogenic changes of epithelial cells by promoting cell survival and proliferation under invitro and in vivo conditions</strong>

Dec. 14(Thu.), 2017

Odd Number / 16:00-17:00, Exhibition Tumor immunology-1 (Tumor Yutaka
antigens, antigen presenting
Even Number / 17:00-18:00 Hall
Kawakami
cells, anti-tumor T cells)

Hirokazu
Matsushita

100433 3-H-W41-1-O/P

Presentation: 7min,
Discussion: 3min

Takumi Itoh

Department of Therapy Development andInnovation for Immune disorders and Cancers,
Graduate School of Medicine, Juntendo
University, Tokyo, Japan

IL-26 facilitates angiogenesis and skin inflammation via inducing FGF2 production in amurine model of imiquimod-induced psoriasis

Dec. 14(Thu.), 201714:25-15:45

Room H

Tissue-specific immune
diseases III

Keishi Fujio

MotomuHashimoto

100434 3-H-W40-15-O/P

Presentation: 7min,
Discussion: 3min

Yuta Kogure

Division of Mucosal Immunology, Department ofMesenchymal-mediated skin-specific regulatory system for the control of tissue resident
Microbiology and Immunology, The Institute ofMedical Science, The University of Tokyo, Tokyo, mast cells
Japan

Dec. 14(Thu.), 201712:50-14:10

Room H

Granulocyte & Mast cells

Atsuhito Nakao

YosukeKurashima100435 3-B-W29-6-P

Poster Presentation

TsutomuYanagibashi

Toyama Prefectural Institute for Pharmaceutical
Research, Toyama, Japan

IL-5-producing ILC2s in the large intestine contribute to T cell-independent IgA production
through the regulation of eosinophil homeostasis

Dec. 14(Thu.), 2017

Odd Number / 16:00-17:00, Exhibition Innate Lymphocyte-2(ILC1,2,3)
Even Number / 17:00-18:00 Hall

SusumuNAKAE

Shinichiro
SAWA

100436 3-B-W29-12-P

Poster Presentation

Shinichiro Sawa

Institute for Genetic Medicine, Hokkaido
University, Sapporo, Japan

Development of novel mouse models lacking for group 3 innate lymphoid cells.

Dec. 14(Thu.), 2017

Odd Number / 16:00-17:00, Exhibition Innate Lymphocyte-2(ILC1,2,3)
Even Number / 17:00-18:00 Hall

SusumuNAKAE

Shinichiro
SAWA

100437 3-H-W41-16-O/P

Presentation: 7min,
Discussion: 3min

Tomonori Kaifu

Department of Immunology, Tohoku Medical and
DCIR negatively regulates osteoclastogenesis by binding to a novel endogenous ligand
Pharmaceutical University

Dec. 14(Thu.), 201714:25-15:45

Keishi Fujio

MotomuHashimoto

100438 1-G-W13-20-P

Poster Presentation

Yasuhiro Kanda

Department of Immunology and Medical Zoology,
Niigata University Graduate School of Medical
Live imaging of the allogeneic T cell elimination in secondary lymphoid organs
and Dectal sciences

Dec. 12(Tue.), 2017

Odd Number / 16:30-17:30, Exhibition Hematopoiesis and immune
environments
Even Number / 17:30-18:30 Hall

TakashiNagasawa

HitoshiTakizawa

100439 3-I-W42-13-P

Poster Presentation

Kenta Iwasaki

Department of Kidney Disease and Transplant
Immunology, Aichi Medical University School of
Medicine, Aichi, Japan

Differential response of allo-reactive CD4 T-cells against HLA class II expressed on
endothelial cells in the presence of HLA and ABO antibody.

Dec. 14(Thu.), 2017

Odd Number / 16:00-17:00, Exhibition
T cell-2 : T cell signaling
Even Number / 17:00-18:00 Hall

SatoshiMatsudaTadashiYokosuka100440 1-I-W17-5-P

Poster Presentation

Asami Hanazawa

Central Institute for Experimental Animals,
Kawasaki, Japan<strong>NOG human M-CSF transgenic mice enhance differentiation and maturation ofhuman monocytes and macrophages</strong>

Dec. 12(Tue.), 2017

Odd Number / 16:30-17:30, Exhibition
Human Immunology
Even Number / 17:30-18:30 Hall

Koji Yasutomo Keishi Fujio

100441 1-A-W1-6-P

Poster Presentation

Jung Yeon Hong

Department of Pediatrics and Institute of Allergy,<strong>Chitotriosidase Regulation of Allergen-induced Airway Inflammation Airways
Brain Korea 21 PLUS Project for Medical
Science, Yonsei University College of Medicine, Hyperresponsiveness and Foxp3<sup>+</sup> Treg Cells</strong>
Seoul, Korea

Dec. 12(Tue.), 2017

Odd Number / 16:30-17:30, Exhibition Allergy-1 : Lower airway
allergic inflammation
Even Number / 17:30-18:30 Hall

Kenji Izuhara

Koubun Yasuda

100442 3-A-W27-6-P

Poster Presentation

Chihiro Ohashi

Kitasato University School of Medicine,
Sagamihara Japan

Spontaneous accumulation of myeloid-derived suppressor cell (MDSC)-likeCD11b<sup>+</sup>/Gr-1<sup>+</sup> cells in the periphery of NF-&kappa;B-inducing
kinase (NIK) mutant mice.

Dec. 14(Thu.), 2017

Odd Number / 16:00-17:00, Exhibition Tolerance and immune
suppression -2
Even Number / 17:00-18:00 Hall

Naganari
OhkuraTakashi Sekiya

100443 2-C-W21-1-O/P

Presentation: 10min,
Discussion: 3min

Kiyomi SHITAOKA and Pharmaceutical Sciences, University of

Majority of tumor infiltrating lymphocytes in B16F10 melanoma recognized tumorassociated antigens, but not melanoma-associated antigens or neoantigens.

Dec. 13
14:25-15:45(Wed.), 2017

Hiroaki Ikeda

Koji Tamada

100444 1-I-W18-11-P

Poster Presentation

Tomo Takebe

Pharmaceutical Sciences, Tokyo University of
Science, Chiba, Japan

A novel mouse model for tracking the fate of follicular helper T cells

Dec. 12(Tue.), 2017

Odd Number / 16:30-17:30, Exhibition
Helper T cells
Even Number / 17:30-18:30 Hall

Masakatsu
YAMASHITA

Motoko Y.
KIMURA

100445 1-I-W17-6-P

Poster Presentation

Ikumi Katano

Central Institute for Experimental Animals,
Kawasaki, Japan

Human macrophages which developed into NOG-human GM-CSF/IL-3 Tg mice after
hematopoietic stem cells phagocytosed mouse erythrocytes and induced serious anemia.

Dec. 12(Tue.), 2017

Odd Number / 16:30-17:30, Exhibition
Human Immunology
Even Number / 17:30-18:30 Hall

Koji Yasutomo Keishi Fujio

100446 3-B-W29-7-O/P

Presentation: 11min,
Discussion: 2min

Naoko SatohLaboratory for Intestinal Ecosystem, Center for
Integrative Medical Science, RIKEN

Identification of an ILC2 population in the stomach which responds to commensal andpathogenic bacteria

Dec. 14(Thu.), 201714:25-15:45

100447 2-F-W22-15-P

Poster Presentation

Fu Lian LYU

Department of Immunology, Graduate School of
A novel method to produce high amounts of recombinant MHC/peptide complexes for
Medicine and Pharmaceutical Sciences,
University of Toyama, 2630 Sugitani, Toyama
isolation of antigen-specific human TCRs
930-0194, Japan

100448 3-B-W29-2-P

Poster Presentation

Koga Satoshi

Laboratory for Innate Immune Systems, RIKEN
IMS, Kanagawa, Japan

Developmental trajectory of tissue-resident ILC2 from primary lymphoid organs to theperipheral microenvironment

Dec. 14(Thu.), 2017100449 3-I-W42-7-P

Poster Presentation

OGAWA Shuhei

Division of Immunobiology, Research Institute for
The regulation of CD28 tyrosine phosphorylation and the function of CD28-mediatedBiomedical Sciences, Tokyo University of
costimulation.
ScienceDec. 14(Thu.), 2017

Department of Innovative Cancer
Immunotherapy, Graduate School of Medicine
Toyama, Toyama City, Japan

20 / 30

Room H

Room C

Virus infection-1

Tissue-specific immune
diseases III

Cell therapy

SusumuNAKAE

Shinichiro
SAWA

TaishinAkiyamaTakeshi Nitta

Odd Number / 16:00-17:00, Exhibition Innate Lymphocyte-2(ILC1,2,3)
Even Number / 17:00-18:00 Hall

SusumuNAKAE

Shinichiro
SAWA

Odd Number / 16:00-17:00, Exhibition
T cell-2 : T cell signaling
Even Number / 17:00-18:00 Hall

SatoshiMatsudaTadashiYokosukaDec. 13
16:00-17:00(Wed.), 2017

Room B

Innate Lymphocyte-2(ILC1,2,3)

Exhibition T cell-1: T cell development
and repertoire selection
HallThe 46th Annual Meeting of The Japanese Society for Immunology
Submission ID

Program No.

Oral Presentation Time

1st Author

Submission ID orderAffiliation

Title

Date

Time

Venue

Session Title

Chair1Chair2

Kenji Izuhara

Koubun Yasuda

100450 1-A-W1-7-P

Poster Presentation

Mi Na Kim

Department of Pediatrics and Institute of Allergy,
Brain Korea 21 PLUS Project for Medical
ALCAM on dendritic cell contributes Th2 response in allergic airway inflammation
science, Yonsei University College of Medicine,
Seoul, Republic of Korea

100451 2-G-W23-7-P

Poster Presentation

Ken Igawa

Department of Dermatology, Dokkyo Medical
University, Mibu, Japan

Therapeutic effect of the improved version Stat6 decoy ODN containing ointment utilizing
new technology ILTS&reg; on murine skin inflammatory responses.

Dec. 13
16:00-17:00(Wed.), 2017

Exhibition Allergy-3 : Allergic dermatitis,
food allergy and allergic
Kenji IzuharaHallconjunctivitis

Tomohiro
Yoshimoto

100452 3-F-W37-17-O/P

Presentation: 7min,
Discussion: 2min

Hideki Asanuma

National Institute of Infectious Diseases, Tokyo,
JAPAN<strong>Essential roles for protective SIgA Abs induced by nasal G9.1 combined influenza
VLP vaccine</strong>

Dec. 14(Thu.), 201714:25-15:45

Room F

Jun Kunisawa

100453 3-D-W32-13-P

Poster Presentation

Yui Kuroki

Reserch Institute for Biomedical Sciences,Tokyo Analysis of antigen prosenting cells that inducec CD8+ CD11c+ T cells in tumor
University of Science
microenviroment

Dec. 14(Thu.), 2017

Odd Number / 16:00-17:00, Exhibition Tumor immunology-1 (Tumor Yutaka
antigens, antigen presenting
Even Number / 17:00-18:00 Hall
Kawakami
cells, anti-tumor T cells)

Hirokazu
Matsushita

100454 1-D-W8-12-P

Poster Presentation

Warunthorn
MonwanLaboratry of Molecular Immunobiology, Graduate
Characterization of Nucleoporin (Nup) genes that mediate antimicrobial innate immune
School of Biological Sciences, Nara Institute of
responses
Science and Technology, Nara, Japan

Dec. 12(Tue.), 2017

Odd Number / 16:30-17:30, Exhibition
Virus infection-2
Even Number / 17:30-18:30 Hall

HiroyukiOshiumi100455 2-G-W23-8-P

Poster Presentation

Sekiguchi Kota

Laboratory of Microbiology and Immunology,
School of Pharmaceutical Sciences, University of A triacylglycerol, tributyrin, has an adjuvant effect in a mouse contact hypersensitivity model
Shizuoka, Shizuoka, Japan

Dec. 13
16:00-17:00(Wed.), 2017

Exhibition Allergy-3 : Allergic dermatitis,
food allergy and allergic
Kenji IzuharaHallconjunctivitis

Tomohiro
Yoshimoto

100456 3-H-W40-22-O/P

Presentation: 7min,
Discussion: 3min

Tomoyuki Bando

Ono pharmaceutical co., ltd. Exploratory
Research Laboratories, Osaka, JAPAN<strong>Differential usage of COX-1 and COX-2 in prostaglandin production by mast cells
and basophils</strong>

Dec. 14(Thu.), 201712:50-14:10

Room H

Atsuhito Nakao

YosukeKurashima100457 3-F-W36-12-P

Poster Presentation

Naoya Tsugawa

Department of Gastroenterology, Graduate
School of Medical Science, Tokyo Medical and
Dental University, Tokyo, Japan<strong>Verification of immunoglobulin A regulation of mucosal microflora andhomeostasis</strong>

Dec. 14(Thu.), 2017

Odd Number / 16:00-17:00, Exhibition
Mucosal-Skin Immunity-2
Even Number / 17:00-18:00 Hall

Koji Hase

Gyohei Egawa

100458 1-E-W10-12-O/P

Presentation: 7min,
Discussion: 3min

Keigo Ueno

Department of Chemotherapy and Mycoses,
National Institute of Infectious Diseases, Tokyo,
Japan

Dendritic cell-based vaccination induces lung resident memory Th17 cells that ameliorate
pulmonary infection with highly virulent <em>Cryptococcus gattii</em>

Dec. 12(Tue.), 201714:55-16:15

Room E

Immune response to
mycobacteial and fungal
infections

Kazuyoshi
Kawakami

Hiromitsu Hara

100459 2-I-W25-6-O/P

Presentation: 7min,
Discussion: 3min

Yoshimitsu
Nakanishi

Department of Respiratory Medicine and ClinicalSema6D prevents excess inflammation during high-fat feeding by controlling mitochondrial
Immunology, Graduate School of medicine,
metabolism.
Osaka University, Osaka, Japan

Dec. 13
14:25-15:45(Wed.), 2017

Room I

Dendritic cells andMacrophages-1: Organspecific Immune Tolerance

Satoshi Ishido

Kenichi Asano

100460 3-A-W27-8-P

Poster Presentation

Sayuri Fukushima

Graduate School of Food, Agricultural andEnvironmental Sciences, Miyagi University,
Miyagi, Japan

Specific expression of C3 components, C3b, iC3b with increase of IL-10 and TGF-&beta; inuterus&rsquo;s endometrium of mouse for the latter pregnant period

Dec. 14(Thu.), 2017

Odd Number / 16:00-17:00, Exhibition Tolerance and immune
suppression -2
Even Number / 17:00-18:00 Hall

Naganari
OhkuraTakashi Sekiya

100461 3-I-W42-12-O/P

Presentation: 7min,
Discussion: 3min

Naoyuki Kondo

Kansai medical university, Hirakata, Osaka,Japan

NDR1 acts as a molecular hub for the organization of immunological synapse

Dec. 14(Thu.), 201712:50-14:10

100462 3-D-W33-4-O/P

Presentation: 7min,
Discussion: 3min

Haruka Wada

Division of Immunobiology, Institute for Genetic
Medicine, Hokkaido University

Tumor initiating cell in immunocompetent animal defined by immunological features

Dec. 14(Thu.), 201714:25-15:45

100463 1-H-W16-15-P

Poster Presentation

Riyoko Tamai

Department of Oral Medical Science, Ohu
University School of Dentistry, Fukushima,
Japan

Alendronate induces caspases-independent cell death via NLRP3 and ASC

100464 3-F-W36-13-P

Poster Presentation

Takashi Nagaishi

Department of Gastroenteroogy, Graduate
School of Medical Science, Tokyo Medical and
Dental University

100465 3-B-W29-3-P

Poster Presentation

YasutakaMotomura

100466 1-I-W17-9-P

Poster Presentation

100467 2-C-W21-4-P

Dec. 12(Tue.), 2017

Odd Number / 16:30-17:30, Exhibition Allergy-1 : Lower airway
allergic inflammation
Even Number / 17:30-18:30 Hall

Mucosal-Skin Immunity-3

Granulocyte & Mast cells

Eiji Umemoto

Takashi Fujita

Room IT cell-2 : T cell signaling

SatoshiMatsudaTadashiYokosuka

Room D

Tumor immunology-2(Immunosuppression andmodulation in tumor
immunity)Toshihiko
Torigoe

Yoshihiro
Hayakawa

Dec. 12(Tue.), 2017

Odd Number / 16:30-17:30, Exhibition
Takayuki
Cytokines and chemokines-2
Even Number / 17:30-18:30 Hall
YoshimotoTakashi
Kobayashi<strong><em>XXX</em></strong>

Dec. 14(Thu.), 2017

Odd Number / 16:00-17:00, Exhibition
Mucosal-Skin Immunity-2
Even Number / 17:00-18:00 Hall

Koji Hase

Gyohei Egawa

Laboratory for Innate Immune Systems, RIKEN
Center for Integrative Medical Sciences,
Yokohama, Japan

Regulation of ILC2-mediated antigen non-specific immune responses by cysteinyl
leukotrieneDec. 14(Thu.), 2017

Odd Number / 16:00-17:00, Exhibition Innate Lymphocyte-2(ILC1,2,3)
Even Number / 17:00-18:00 Hall

SusumuNAKAE

Shinichiro
SAWA

Kohsuke IMAI

Department of pediatrics, Tokyo Medical and
Dental University, Tokyo, Japan

Diagnostic method for primary immunodeficiency using spectral flow cytometry

Dec. 12(Tue.), 2017

Odd Number / 16:30-17:30, Exhibition
Human Immunology
Even Number / 17:30-18:30 Hall

Koji Yasutomo Keishi Fujio

Poster Presentation

Eiji Kobayashi

Department of Immunology, University of
Toyama, Toyama, JapanTCR repertoire analysis of antigen-specific T cells using immunospot array assay on a chip
(T-ISAAC) technology

Dec. 13
16:00-17:00(Wed.), 2017

Exhibition
Cell therapy
Hall100468 3-B-W29-9-O/P

Presentation: 11min,
Discussion: 2min

Mariko Kamioka

Division of Mucosal Immunology, Department of
Innate and adaptive immune cells regulate Paneth cell granule formation and &alpha;Microbiology and Immunology, The Institute ofMedical Science, The University of Tokyo, Tokyo, defensin secretion
Japan

Dec. 14(Thu.), 201714:25-15:45

Room B

100469 3-D-W32-14-O/P

Presentation: 7min,
Discussion: 3min

Hiroshi HIGUCHI

School of Medicine, Tokai University, Kanagawa, Phosphatidylserine-mediated incorporation of tumor-derived exosomes and phenotypicJapanchanges in human macrophages

Dec. 14(Thu.), 201712:50-14:10

Room D

100470 3-A-W27-9-P

Poster Presentation

Naoko Negishi

Atopy (Allergy) Research Center, Juntendo
University Graduate School of Medicine, Tokyo,
Japan

CD155-mediated signaling through TIGIT is involved in serial transfer of tolerant state into
na&iuml;ve T cells

Dec. 14(Thu.), 2017100471 3-H-W40-16-P

Poster Presentation

Makiko Uchida

Department of Biological Science andTechnology, Graduate School of Industrial
Science and Technology, Tokyo University of
Science, Tokyo, Japan

Functional analysis of transcription factor Ehf.

Dec. 14(Thu.), 201721 / 30

Hiroaki Ikeda

Koji Tamada

Innate Lymphocyte-2(ILC1,2,3)

SusumuNAKAE

Shinichiro
SAWA

Tumor immunology-1 (Tumor
antigens, antigen presenting
cells, anti-tumor T cells)

YutakaKawakami

Hirokazu
Matsushita

Odd Number / 16:00-17:00, Exhibition Tolerance and immune
suppression -2
Even Number / 17:00-18:00 Hall

Naganari
OhkuraTakashi Sekiya

Odd Number / 16:00-17:00, Exhibition
Granulocyte & Mast cells
Even Number / 17:00-18:00 Hall

Atsuhito Nakao

YosukeKurashima

The 46th Annual Meeting of The Japanese Society for Immunology
Submission ID

Program No.

Oral Presentation Time

1st Author

Submission ID orderAffiliation

Title

Date

Time

Venue

Session Title

Chair1Chair2100472 3-H-W40-17-P

Poster Presentation

Kazuki Saida

Laboratory of Molecular Biology and
Immunology, Department of Biological Science
Mucosal mast cell differentiation is regulated by cross-talk between Notch signaling andand Technology, Faculty of Industrial Scienceand Technology, Tokyo University of Science, 6- TGF-&beta; signaling.
3-1 Niijuku, Katsushika-ku, Tokyo 125-8585,

100473 1-A-W1-12-P

Poster Presentation

Asako TanoueDepartment of Pulmonary Medicine, Graduate
School of Medical and Dental Sciences,
Kagoshima University, Kagoshima, JapanThe role of group III secreted phospholipase A2 in allergic asthma

Dec. 12(Tue.), 2017

Odd Number / 16:30-17:30, Exhibition Allergy-1 : Lower airway
allergic inflammation
Even Number / 17:30-18:30 Hall

100474 1-B-W4-7-O/P

Presentation: 7min,
Discussion: 2min

Yukari Saito

Department of Immune Regulation, ResearchCenter for Hepatitis and Immunology, ResearchInstitute, National Center for Global Health andMedicine, Chiba, Japan

Activation of NK/group1-innate lymphoid cells in adipose tissues depends on thecomposition of fatty acids in high fat diet.

Dec. 12(Tue.), 201714:55-16:15

Room B

Endogenous innate immunity
and inflammation-2

100475 3-C-W31-15-O/P

Presentation: 8min,
Discussion: 3min

Takumi Kawasaki

Nara Institute of Science and Technology(NAIST), Nara, Japan<strong>Obesity regulation by PIKfyve, a lipid kinase, in macrophage</strong>

Dec. 14(Thu.), 201714:25-15:45

Room C

Dendritic cells andTsuneyasu
Macrophages-3: Inflammatory
KaishoResponses

100476 3-B-W29-8-O/P

Presentation: 11min,
Discussion: 2min

Takato Kobayashi

Laboratory for Innate Immune Systems, RIKEN
IMSCharacterization of group 2 innate lymphoid cells in glandular tissue

Dec. 14(Thu.), 201714:25-15:45

Room B

Innate Lymphocyte-2(ILC1,2,3)

SusumuNAKAE

Shinichiro
SAWA

100477 1-H-W16-8-O/P

Presentation: 6min,
Discussion: 2min

Jae-won Chang

Graduate School of Frontier Sciences, The
University of Tokyo, Chiba, JapanThe first distinction and observation of single molecular dynamics between Interleukin-2 with
Dec. 12Intereleukin-2 receptor and Interleukin-15 with Interleukin-15 receptor through Diffracted X(Tue.), 2017
ray Tracking

14:55-16:15

Room H

Cytokines and chemokines-2

Takayuki
YoshimotoTakashi
Kobayashi

100478 3-I-W42-14-O/P

Presentation: 7min,
Discussion: 3min

Akiko HashimotoTane

RIKEN Center for Integrative Medical Science,
Yokohama, Japan

Molecular assembly and function of PTPN22 in T cell receptor signaling

Dec. 14(Thu.), 201712:50-14:10

Room IT cell-2 : T cell signaling

SatoshiMatsudaTadashiYokosuka

100479 1-D-W7-1-O/P

Presentation: 6min,
Discussion: 2min

Satoshi Fukuyama and Immunology, Institute of Medical Science,

Effect of aging on the host response to avian influenza A(H7N9) virus infection in nonhuman primates

Dec. 12(Tue.), 201713:20-14:40

Room D

Virus infection-1

Taro Kawai

Mitsutoshi
Yoneyama

100480 3-G-W39-10-O/P

Presentation: 7min,
Discussion: 4min

Yoshimichi
Okayama

Allergy and Immunology Research Project Team, Autoantibodies (AAbs) against the Fc&epsilon;RI &alpha;-chain and IgE in patients withCenter for Institutional Research and Medical
chronic spontaneous urticaria (CSU) induced statistically higher ability of Fc&epsilon;RI
Education, Nihon University School of Medicine aggregation compared with non-atopic control (NC) subjects

Dec. 14(Thu.), 201714:25-15:45

Room G

Systemic autoimmune
disease (3)KimitoKawahata

ShingoNakayamada

100481 2-H-W24-1-O/P

Presentation: 7min,
Discussion: 3min

Miwa Sasai

Department of Immunoparasitology, ResearchInstitute for Microbial Diseases, Osaka
University, Osaka, Japan<strong>Critical roles of GABARAPs on interferon-mediated cell-autonomous immune
responses against <em>T. gondii</em> infection</strong>

Dec. 13
14:25-15:45(Wed.), 2017

Room H

Immune response to parasite
infections

Yoichi
Maekawa

Masahiro
Yamamoto

100482 3-H-W41-4-O/P

Presentation: 7min,
Discussion: 3min

Taro Watabe

Department of gastroenterology, Tokyo Medical
and Dental University, Tokyo, Japan

Analysis of ileocecal immune response in an experimental colitis model using intra-vital
imaging

Dec. 14(Thu.), 201714:25-15:45

Room H

Tissue-specific immune
diseases III

Keishi Fujio

MotomuHashimoto

100483 1-H-W15-2-O/P

Presentation: 6min,
Discussion: 2min

Mayu Kaetsu

Department of Life Science and Medical
Bioscience, Waseda University, Tokyo, Japan

Colonic inflammation induces a transient increase in serum LECT2 level.

Dec. 12(Tue.), 201713:20-14:40

Room H

Cytokines and chemokines-1

Masaaki
Murakami

Akihiro Kimura

100484 1-A-W2-8-O/P

Presentation: 7min,
Discussion: 3minKazuya Takeda

Laboratory of Immune regulation, Immunology
Frontier Research center, Osaka University,
Suita, Japan

Ectopic T-B interaction for antigen-specific IgE antibody responses in nasal polyps of
Eosinophilic chronic rhinosinusitis patients

Dec. 12(Tue.), 201714:55-16:15

Room A

Allergy-2: Upper airway
allergic inflammation andallergic responses

Tomohiro
YoshimotoRyoji Yagi

100485 3-F-W36-16-P

Poster Presentation

Takayuki MIURA

Deptartment of Plastic and Reconstructive
Surgery, Tohoku University, Sendai, Japan

Effect of Dectin-2-mediated signaling on skin wound healing and NETosis

Dec. 14(Thu.), 2017

Odd Number / 16:00-17:00, Exhibition
Mucosal-Skin Immunity-2
Even Number / 17:00-18:00 Hall

Koji Hase

Gyohei Egawa

100486 3-F-W37-4-O/P

Presentation: 7min,
Discussion: 2min

Chieko Ishifune

Department of Immunology and Parasitology,
Institute of Biomedical Sciences, Tokushima
University Graduate School, Tokushima, Japan

Notch signal controls the number of
TCR&alpha;&beta;<sup>+</sup>CD8&alpha;&alpha;<sup>+</sup> intraepithelial
lymphocytes via phospholipid asymmetry by maintaining fllipase ATP8a2

Dec. 14(Thu.), 201714:25-15:45

Eiji Umemoto

Jun Kunisawa

100487 3-B-W28-7-P

Poster Presentation

Masashi SATOH

Department of Immunology, Kitasato University,
School of Medicine, Sagamihara, Japan

Generation of CD1d-negative NKT-cell hybridomas

Dec. 14(Thu.), 2017

Odd Number / 16:00-17:00, Exhibition Innate Lymphocyte-1 (NKT,
MAIT, gdT, NK)
Even Number / 17:00-18:00 Hall

Kensuke
ShibataKazuyaIWABUCHI

100488 3-H-W40-24-O/P

Presentation: 7min,
Discussion: 3min

Takuya OHTA

Department of Immune Regulation, Tokyo
Medical and Dental University Graduate School,
Tokyo, Japan

Skin-resident memory CD4<sup>+</sup> T cells play an essential role in acquired tickresistance through IL-3-mediated basophil recruitment

Dec. 14(Thu.), 201712:50-14:10

Room H

Granulocyte & Mast cells

Atsuhito Nakao

YosukeKurashima100489 3-E-W34-4-O/P

Presentation: 7min,
Discussion: 3min

Saori Fukao

Research Institute for Biomedical Sciences,
Tokyo University of Science, Chiba, Japan

Regulation of IgE production by an RNA binding protein

Dec. 14(Thu.), 201712:50-14:10

Room EB cell development andfunction

Yoshiteru
Sasaki

Reiko Shinkura100490 1-E-W9-6-O/P

Presentation: 7min,
Discussion: 3min

Seitaro Nakagawa Department of Dermatology, Chiba University<em>Staphylococcus aureus </em>virulent PSM&alpha; peptides induce keratinocyte IL-1
and IL-36 release to orchestrate IL-17-dependent skin inflammation

Dec. 12(Tue.), 201713:20-14:40

Room E

Immune response to bacteial
infections

Goro Matsuzaki Yuki Kinjo

100491 1-E-W9-5-O/P

Presentation: 7min,
Discussion: 3min

Shogo Takatsuka

Dept. Chemother. Mycoses, Nat. Inst. Infect.
Dis.

Follicular helper NKT cells augment germinal center B cell formation by a protein-based
pneumococcal vaccine

Dec. 12(Tue.), 201713:20-14:40

Room E

Immune response to bacteial
infections

Goro Matsuzaki Yuki Kinjo

100492 3-H-W41-15-O/P

Presentation: 7min,
Discussion: 3min

Akira Taruya

Department of Cardiovascular Medicine,
Wakayama Medical University, Wakayama,Japan

Decline of lysyl oxidase protein causes acute aortic dissection in Spi-B knockout mice

Dec. 14(Thu.), 201714:25-15:45

Room H

Tissue-specific immune
diseases III

Keishi Fujio

MotomuHashimoto

100493 1-B-W4-5-O/P

Presentation: 7min,
Discussion: 2min

Maehara Akie

Atopy (Allergy) Research Center, Juntendo
University Graduate School of Medicine, Tokyo,
Japan

Identification and characterization of a novel mutation of NLRP1 in a patient with a raredisease involving severe liver fibrosis

Dec. 12(Tue.), 201714:55-16:15

Room B

Endogenous innate immunity
and inflammation-2

Osamu
Takeuchi

SachikoTakamura(Akashi)

Division of Virology, Department of Microbiology
University of Tokyo, Tokyo, Japan

22 / 30

Dec. 14(Thu.), 2017

Odd Number / 16:00-17:00, Exhibition
Granulocyte & Mast cells
Even Number / 17:00-18:00 Hall

Atsuhito Nakao

YosukeKurashima

Kenji Izuhara

Koubun Yasuda

Osamu
Takeuchi

SachikoTakamura(Akashi)Room F

Mucosal-Skin Immunity-3

Rikinari
Hanayama

The 46th Annual Meeting of The Japanese Society for Immunology
Submission ID

Program No.

Oral Presentation Time

1st Author

Submission ID orderAffiliation

Title

Date

Time

Venue

Session Title

Chair1Chair2100494 3-A-W26-8-P

Poster Presentation

Yuka Tanaka

Department of Gastroenterological andTransplant Surgery, Hiroshima University,
Hiroshima, Japan100495 3-B-W28-8-P

Poster Presentation

Shusaku
Kobayashi

Department of Immunology, Kitasato University
Graduate School of Medical Sciences,
Sagamihara, Japan100496 1-G-W13-6-O/P

Presentation: 6min,
Discussion: 2min

Yukiko Doi

Department of Hematology and Oncology, Osaka
SATB1 expression is useful to identify the lymphoid-lineage-biased trajectory of functionally
University Graduate School of Medicine, Suita,
fluctuating hematopoietic stem cells.
Osaka, Japan

Dec. 12(Tue.), 201713:20-14:40

Hematopoiesis and immune
environments

TakashiNagasawa

HitoshiTakizawa

100497 1-G-W13-2-P

Poster Presentation

Eriko Sumiya

Institute for Genetic Medicine, Hokkaido
University, Sapporo, Japan

Fate mapping of RANKL-expressing cells in the fetal bone

Dec. 12(Tue.), 2017

Odd Number / 16:30-17:30, Exhibition Hematopoiesis and immune
environments
Even Number / 17:30-18:30 Hall

TakashiNagasawa

HitoshiTakizawa

100498 1-G-W13-19-P

Poster Presentation

Satomi Komori

Division of Molecular and Cellular Signaling,
Department of Biochemistry and Molecular
Biology, Kobe University Graduate School of
Medicine, Kobe, Japan<strong>Development of a novel primary culture system for lymphoid organ fibroblastic
reticular cells</strong>

Dec. 12(Tue.), 2017

Odd Number / 16:30-17:30, Exhibition Hematopoiesis and immune
environments
Even Number / 17:30-18:30 Hall

TakashiNagasawa

HitoshiTakizawa

100499 2-A-W19-5-O/P

Presentation: 7min,
Discussion: 3min

Kiyoshi Hirahara

Department of Immunology, Graduate School of Memory-type ST2<sup>+</sup>CD4<sup>+</sup> T cells participate in the steroidMedicine, Chiba University
resistant pathology of eosinophilic pneumonia

Dec. 13
14:25-15:45(Wed.), 2017

Room A

Mucosal-Skin Immunity-1

Kenji
Kabashima

Yoshiyuki Goto

100500 3-C-W30-11-O/P

Presentation: 7min,
Discussion: 3min

Miyuki Watanabe

Department of Molecular Immunology, Research
Early FcR&gamma;-Erk signaling determines cytokine profile of dendritic cells through CInstitute for Microbial Diseases, Osaka
type lectin receptors
University, Osaka, Japan

Dec. 14(Thu.), 2017

Room C

Dendritic cells andTomohiko
Macrophages-2: Development
Tamuraand Recognition

100501 2-G-W23-9-P

Poster Presentation

Takeshi Wada

Division of Molecular Medicine, Institute for
Genome Research, Tokushima University,
Tokushima, Japan

Exacerbation of oxazolone-induced atopic dermatitis in a mouse model of hyper-IgE
syndrome

Dec. 13
16:00-17:00(Wed.), 2017

100502 3-G-W39-6-P

Poster Presentation

Hidekata Yasuoka

Division of Rheumatology, Department ofInternal Medicine, Keio University School of
Medicine, Tokyo, Japan

Phenotype of platelet is altered in circulation of patients with rheumatoid arthritis

Dec. 14(Thu.), 2017

100503 2-C-W21-9-O/P

Presentation: 10min,
Discussion: 3min

Seiji Nagano

Institute for Frontier Life and Medical Sciences,
Kyoto University<strong>iPSCs transduced with TCR gene give rise to potent CTLs with antigen specificcytotoxic activity comparable to those from T-iPSCs </strong>

Dec. 13
14:25-15:45(Wed.), 2017

100504 3-F-W37-3-P

Poster Presentation

Ryoki Kobayashi

Nihon University, School of Dentistry at Matsudo, Characterization of Innate lymphoid cells in inflamed gingiva of mice infected with
Chiba, Japan<em>Porphyromonas gingivalis</em>

100505 3-I-W43-7-P

Poster Presentation

Shizue Tani-ichi

Institute for Frontier Life and Medical Sciences,
Kyoto University, Kyoto, Japan

Presentation: 7min,
Discussion: 3min

Psychoimmunology, Institute for Genetic

100506 1-C-W5-6-O/P

Daisuke Kamimura Medicine, Graduate School of Medicine,

100507 3-D-W32-7-O/P

Presentation: 7min,
Discussion: 3min

Taiki Moriya

100508 1-H-W15-4-O/P

Presentation: 6min,
Discussion: 2min

100509 3-C-W30-4-P

Human endothelial-like cells transdifferentiated from peripheral
CD14<sup>+</sup>monocytes inhibit T cells in response to allo-stimulation

Dec. 14(Thu.), 2017

Odd Number / 16:00-17:00, Exhibition Tolerance and immune
suppression -1
Even Number / 17:00-18:00 Hall

Taku Okazaki

Shunsuke
ChikumaCardiac CD1d+ cells that present &alpha;-GalCer and activate NKT cells

Dec. 14(Thu.), 2017

Odd Number / 16:00-17:00, Exhibition Innate Lymphocyte-1 (NKT,
MAIT, gdT, NK)
Even Number / 17:00-18:00 Hall

Kensuke
ShibataKazuyaIWABUCHI

12:50-14:10

Room G

Exhibition Allergy-3 : Allergic dermatitis,
food allergy and allergic
Kenji IzuharaHallconjunctivitis

Odd Number / 16:00-17:00, Exhibition Systemic autoimmune
disease (3)Even Number / 17:00-18:00 Hall
Room C

Cell therapy

Masafumi
Nakayama
Tomohiro
Yoshimoto

KimitoKawahata

ShingoNakayamada

Hiroaki Ikeda

Koji Tamada

Jun Kunisawa

Dec. 14(Thu.), 2017

Odd Number / 16:00-17:00, Exhibition
Mucosal-Skin Immunity-3
Even Number / 17:00-18:00 Hall

Eiji Umemoto

Exploring the signals upregulating IL-7R&alpha; expression via NF&kappa;B activation in T
cells

Dec. 14(Thu.), 2017

Odd Number / 16:00-17:00, Exhibition
T cell-3 : T cell function
Even Number / 17:00-18:00 Hall

Harumi Suzuki Ei Wakamatsu<strong>Light-Gateway Reflex; Photopic light suppresses retinal inflammation via downregulation of a regional adrenergic pathway</strong>

Dec. 12(Tue.), 201713:20-14:40

Room C

Tissue-specific immune
diseases I

Mitsuru
Matsumoto

Daisuke
Kamimura

Laboratory of Immunology, Faculty of Pharmacy, Tumor cell death induction enhances tumor infiltrating dendritic cell migration and increases
Osaka Ohtani University, Osaka, Japan
in tumor antigen-specific T cells.

Dec. 14(Thu.), 201712:50-14:10

Room D

Tumor immunology-1 (Tumor
antigens, antigen presenting
cells, anti-tumor T cells)

YutakaKawakami

Hirokazu
Matsushita

Sunyi Joo

Division of Mucosal Immunology, Department of<strong>Critical role of the CCR5-CCL5 cascade for the preferential migration of HSV-2Microbiology and Immunology, The Institute ofMedical Science, The University of Tokyo, Japan specific effector cells to the vaginal mucosa upon intranasal immunization </strong>

Dec. 12(Tue.), 201713:20-14:40

Room H

Cytokines and chemokines-1

Masaaki
Murakami

Akihiro Kimura

Poster Presentation

Hideki Arimochi

Graduate School of Biomedical Sciences,
Tokushima University, Tokushima, JapanFXR as a regulator of <em>Psmb8</em> expression is associated with macrophage
differentiation

Dec. 14(Thu.), 2017

Odd Number / 16:00-17:00, Exhibition Dendritic cells andTomohiko
Macrophages-2: Development
Even Number / 17:00-18:00 Hall
Tamuraand Recognition

Masafumi
Nakayama

100510 3-A-W27-11-P

Poster Presentation

Tomoyuki
Yamaguchi

Research Institute Nozaki Tokushukai, Osaka,Japan<strong>A simulation model of immune response predicts essential functions of Treg tomaintain immune tolerance</strong>

Dec. 14(Thu.), 2017

Odd Number / 16:00-17:00, Exhibition Tolerance and immune
suppression -2
Even Number / 17:00-18:00 Hall

Naganari
OhkuraTakashi Sekiya

100511 3-B-W28-9-P

Poster Presentation

IwayamaToshitsugu

Kitasato University School of Medicine,
Sagamihara, Japan

Development of experimental autoimmune myocarditis model and experimental therapeutics Dec. 14
with NKT cell ligands(Thu.), 2017

Odd Number / 16:00-17:00, Exhibition Innate Lymphocyte-1 (NKT,
MAIT, gdT, NK)
Even Number / 17:00-18:00 Hall

Kensuke
ShibataKazuyaIWABUCHI

100512 1-G-W13-21-P

Poster Presentation

Yoshihiro Ueda

Molecular Genetics, Institute of Biomedical
Science, Kansai Medical University<strong>Regulation of cell polarization by Rap1 via NDR/Rab8 axis upon chemokine
stimulation</strong>

Dec. 12(Tue.), 2017

Odd Number / 16:30-17:30, Exhibition Hematopoiesis and immune
environments
Even Number / 17:30-18:30 Hall

TakashiNagasawa

HitoshiTakizawa

100513 1-I-W18-12-P

Poster Presentation

Kazuki Sakamoto

Pharmaceutical Sciences, Tokyo University of
Science, Chiba, Japan

Dysregulation of humoral immunity in Foxp3 conditional knockout mice

Dec. 12(Tue.), 2017

Odd Number / 16:30-17:30, Exhibition
Helper T cells
Even Number / 17:30-18:30 Hall

Masakatsu
YAMASHITA

Motoko Y.
KIMURA

Makoto Tsuiji

Department of Microbiology, Hoshi University
School of Pharmacy and Pharmaceutical
Sciences

Effects of linoleic acid oxide 13-HODE and 13-HPODE on immune responses.

Dec. 14(Thu.), 2017

Odd Number / 16:00-17:00, Exhibition (Immunosuppression andmodulation in tumor
Even Number / 17:00-18:00 Hall

Toshihiko
Torigoe

Yoshihiro
Hayakawa

Atsuhito Nakao

YosukeKurashima

Hokkaido University, Sapporo, Japan

Tumor immunology-2

100514 3-D-W33-12-P

Poster Presentation

immunity)

100515 3-H-W40-18-P

Poster Presentation

Kumi Izawa

Atopy (Allergy) Research Center, Juntendo
University School of Medicine, Tokyo, Japan<strong>Mast cell- and IgE-dependent anaphylaxis is regulated by paired receptors LMIR3and LMIR7</strong>

23 / 30

Dec. 14(Thu.), 2017

Odd Number / 16:00-17:00, Exhibition
Granulocyte & Mast cells
Even Number / 17:00-18:00 Hall

The 46th Annual Meeting of The Japanese Society for Immunology
Submission ID

Program No.

Oral Presentation Time

1st Author

Submission ID orderAffiliation

Title

Date

Time

Venue

Session Title

Chair1Chair2100516 3-A-W27-1-O/P

Presentation: 10min,
Discussion: 3min

Ryoji Kawakami

Immunology Frontier Research Center, Osaka
university, Osaka, Japan

Epigenomic signatures of extrathymic-derived regulatory T-cells

Dec. 14(Thu.), 201714:25-15:45

Room A

Tolerance and immune
suppression -2

Naganari
Ohkura100517 1-E-W9-15-O/P

Presentation: 7min,
Discussion: 3min

Ayako Kaitani

Atopy (Allergy) Research Center, Juntendo
University School of Medicine, Tokyo, Japan

CD300f suppresses neutrophil recruitment to LPS-injected skin: A role of CD300f in gramnegative bacterial skin infections

Dec. 12(Tue.), 201713:20-14:40

Room E

Immune response to bacteial
infections

Goro Matsuzaki Yuki Kinjo

100518 3-I-W42-3-P

Poster Presentation

Matsui Yukihide

Department of molecular immunology, the faculty TCR-stimulation recruits CBP from nucleus to the cytoplasm and affects the proteinof medicine, Toho University, Tokyo, Japan
phosphorylation

Dec. 14(Thu.), 2017

Odd Number / 16:00-17:00, Exhibition
T cell-2 : T cell signaling
Even Number / 17:00-18:00 Hall

100519 1-A-W2-16-O/P

Presentation: 7min,
Discussion: 3min

Ayako Takamori

Atopy (Allergy) Research Center, Juntendo
University School of Medicine, Tokyo, Japan<strong>Ceramide-CD300f interaction inhibits Mrgprb2-mediated mast cell activation andpseudo-allergic drug reactions in mice</strong>

Dec. 12(Tue.), 201714:55-16:15

100520 3-H-W40-19-P

Poster Presentation

Shino Uchida

Atopy (Allergy) Research Center, Juntendo
University School of Medicine, Tokyo, Japan<strong>A critical role of an inhibitory receptor LMIR3 in the pathogenesis of foodallergy</strong>

Dec. 14(Thu.), 2017

100521 3-I-W42-16-P

Poster Presentation

Koji Eshima

Kitasato University School of Medicine

Implication of T-bet, the master regulator of Th1 cells, in the cytotoxicity of murine
CD4<sup>+</sup> T cells

100522 1-B-W3-11-P

Poster Presentation

Motoya Murase

Graduate School of Biological Sciences, Nara
Institute of Science and Technology (NAIST),Nara, Japan

100523 3-E-W34-13-P

Poster Presentation

Nazim Medzhidov

100524 1-C-W5-11-P

Poster Presentation

100525 1-I-W17-10-P

Takashi Sekiya

SatoshiMatsudaTadashiYokosuka

Tomohiro
YoshimotoRyoji Yagi

Odd Number / 16:00-17:00, Exhibition
Granulocyte & Mast cells
Even Number / 17:00-18:00 Hall

Atsuhito Nakao

YosukeKurashima

Dec. 14(Thu.), 2017

Odd Number / 16:00-17:00, Exhibition
T cell-2 : T cell signaling
Even Number / 17:00-18:00 Hall

SatoshiMatsudaTadashiYokosuka

Intravesicular acidification regulates lipopolysaccharide inflammation and tolerance throughToll-like receptor 4 trafficking

Dec. 12(Tue.), 2017

Odd Number / 16:30-17:30, Exhibition Endogenous innate immunity
Tatsuya Saitoh Takuya Uehata
and inflammation-1
Even Number / 17:30-18:30 Hall

Department of Immunology, Medical ResearchInstitute, Tokyo Medical and Dental University,
Tokyo, Japan<strong>Role of poor B cell receptor ubiquitination in efficient antigen presentation</strong>

Dec. 14(Thu.), 2017

Odd Number / 16:00-17:00, Exhibition B cell development andfunction
Even Number / 17:00-18:00 Hall

Yoshiteru
Sasaki

Reiko Shinkura

NatsumiNakayama

Laboratory of Biochemistry, Azabu University

The role of gangliosides in CNS autoimmune diseases

Dec. 12(Tue.), 2017

Odd Number / 16:30-17:30, Exhibition Tissue-specific immune
diseases I
Even Number / 17:30-18:30 Hall

Mitsuru
Matsumoto

Daisuke
Kamimura

Poster Presentation

JeongHoon Park

Department of Immunopathology, IFReC, Osaka <strong>Study of Human Autoimmune Diseases Enabled by Gene Editing in Reporter Cell
University, Osaka, Japan
Lines</strong>

Dec. 12(Tue.), 2017

Odd Number / 16:30-17:30, Exhibition
Human Immunology
Even Number / 17:30-18:30 Hall

Koji Yasutomo Keishi Fujio

100526 1-I-W17-11-P

Poster Presentation

Yuka Kobayashi

Laboratory of Immunology, Institute for FrontierLife and Medical Sciences, Kyoto University,
Kyoto, JapanThe construction and application of human-type artificial lymphoid tissues

Dec. 12(Tue.), 2017

Odd Number / 16:30-17:30, Exhibition
Human Immunology
Even Number / 17:30-18:30 Hall

Koji Yasutomo Keishi Fujio

100527 3-E-W35-6-O/P

Presentation: 7min,
Discussion: 3min

Ari Itoh-Nakadai

Department of Experimental Immunology,
Institute of Development, Aging and Cancer,
Tohoku University, Tokyo, Japan

Secretory leukocyte peptidase inhibitor (SLPI) is highly expressed in long-lived plasma cells

Dec. 14(Thu.), 201714:25-15:45

Room E

Germinal center reaction andplasma cells

Masaki Hikida

Wataru Ise

100528 1-C-W5-8-O/P

Presentation: 7min,
Discussion: 3min

Yasunobu Arima

Division of Psychoimmunology, Institute for
Genetic Medicine and Graduate School of
Medicine, Hokkaido University, Sapporo, Japan

Stress-Gateway Reflex, which establishes brain micro-inflammation at specific vessels,
creates a new neural pathway, which induces the dysregulation of organ homeostasis

Dec. 12(Tue.), 201713:20-14:40

Room C

Tissue-specific immune
diseases I

Mitsuru
Matsumoto

Daisuke
Kamimura

100529 1-B-W4-2-O/P

Presentation: 7min,
Discussion: 2min

Eri Kumaki

Department of Pediatrics and Developmental
biology, Tokyo Medical and Dental University
Graduate School of Medical and Dental
Sciences, Tokyo, Japan

Abberant Neutrophil Function in <em>PSTPIP1</em> mutations

Dec. 12(Tue.), 201714:55-16:15

Room B

Endogenous innate immunity
and inflammation-2

Osamu
Takeuchi

SachikoTakamura(Akashi)100530 3-C-W30-8-P

Poster Presentation

Satoshi Fujiyama

Department of Immunology, Faculty of Medicine,
Identification of marginal zone macrophages by means of flow cytometry
University of Tsukuba , Ibaraki, Japan

Dec. 14(Thu.), 2017

Odd Number / 16:00-17:00, Exhibition Dendritic cells andTomohiko
Macrophages-2: Development
Even Number / 17:00-18:00 Hall
Tamuraand Recognition

Masafumi
Nakayama

100531 3-C-W31-2-P

Poster Presentation

Tatsuo Katagiri

Department of (Pharm)Biology Graduate School
Analysis of macrophage anti-tumor activating component derived from<em> Polyporusof Medicine and Pharmaceutical Sciences,alveolaris</em> extract (PAE)
University of Toyama, Toyama, Japan

Dec. 14(Thu.), 2017

Odd Number / 16:00-17:00, Exhibition Dendritic cells andTsuneyasu
Macrophages-3: Inflammatory
Even Number / 17:00-18:00 Hall
KaishoResponses

Rikinari
Hanayama

100532 1-I-W17-19-P

Poster Presentation

Atsushi Kadowaki

National Institute of Neuroscience, National
Center of Neurology and Psychiatry, Tokyo,
Japan

CCR9+ CD4+ memory T cells dependent on gut microbiota and age are altered insecondary progressive multiple sclerosis

Dec. 12(Tue.), 2017

Odd Number / 16:30-17:30, Exhibition
Human Immunology
Even Number / 17:30-18:30 Hall100533 1-B-W3-13-P

Poster Presentation

Hideki Sanjo

Department of Molecular and Cellular
Immunology, Shinshu University Schhol of
Medicine, Nagano, Japan

Loss of TAK1 leads to TLR-driven macrophage cell death and inflammation that occur by a
TNF-independent mechanism

Dec. 12(Tue.), 2017

Odd Number / 16:30-17:30, Exhibition Endogenous innate immunity
Tatsuya Saitoh Takuya Uehata
and inflammation-1
Even Number / 17:30-18:30 Hall100534 1-H-W16-1-O/P

Presentation: 6min,
Discussion: 2min

Kazuo Okamoto

Department of Osteoimmunology, Graduate
School of Medicine and Faculty of Medicine, The A distinct role of an EF-hand motif protein in the hematopoietic cell lineage
University of Tokyo, Tokyo, Japan

Dec. 12(Tue.), 201714:55-16:15

Room H

Cytokines and chemokines-2

Takayuki
YoshimotoTakashi
Kobayashi

Presentation: 7min,
Discussion: 3min

Department of Immunology, National Institute of

100535 1-C-W5-2-O/P

Chenyang ZHANG Neuroscience, National Center of Neurology and ectopic expression of prolactin under chronic neuroinflammation</strong><strong>Antigen-presenting cells promote Eomes expression in helper T cells throughDec. 12(Tue.), 201713:20-14:40

Room C

Tissue-specific immune
diseases I

Mitsuru
Matsumoto

Daisuke
Kamimura

100536 3-A-W26-9-O/P

Presentation: 10min,
Discussion: 3min

Xiaotong Cui

Laboratory of Infection and Prevention,
Department of Virus Research, Institute for
Frontier Life and Medical Sciences, Kyoto
University, Kyoto, Japan<strong>Interactions between Regnase-1 and Roquin Regulate Helper T Cell
Polarization</strong>

Dec. 14(Thu.), 201712:50-14:10

Room A

Tolerance and immune
suppression -1

Taku Okazaki

Shunsuke
Chikuma

100538 2-F-W22-8-O/P

Presentation: 8min,
Discussion: 3min

Takeshi Nitta

Department of Immunology, The University ofTokyo, Tokyo, Japan<strong>Human thymoproteasome variations influence CD8 T cell repertoire</strong>

Dec. 13
14:25-15:45(Wed.), 2017

Room FT cell-1: T cell development
and repertoire selection

TaishinAkiyamaTakeshi Nitta

Psychiatry, Kodaira, Tokyo, Japan.

24 / 30

Room A

Allergy-2: Upper airway
allergic inflammation andallergic responses

Koji Yasutomo Keishi Fujio

The 46th Annual Meeting of The Japanese Society for Immunology
Submission ID

Program No.

Oral Presentation Time

1st Author

Submission ID orderAffiliation

Title

Date

Time

Venue

Session Title

Chair1Chair2100539 3-F-W37-5-P

Poster Presentation

Taku Naito

Department of Molecular Immunology, Toho
University School of Medicine, Tokyo, Japan

Maintenance of intestinal homeostasis by T cell-expressed Eed.

Dec. 14(Thu.), 2017

Odd Number / 16:00-17:00, Exhibition
Mucosal-Skin Immunity-3
Even Number / 17:00-18:00 Hall

Eiji Umemoto

Jun Kunisawa

100540 1-G-W13-14-P

Poster Presentation

Toshiki Tezuka

Division of Development and Aging, ResearchInstitute for Biomedical Sciences, Tokyo
University of Science, Chiba, Japan

Defects in splenic architectural organization by postnatal deletion of the gene encoding atranscription factor Tlx1 in spleen mesenchymal cells

Dec. 12(Tue.), 2017

Odd Number / 16:30-17:30, Exhibition Hematopoiesis and immune
environments
Even Number / 17:30-18:30 Hall

TakashiNagasawa

HitoshiTakizawa

100541 3-F-W36-6-P

Poster Presentation

Toshiyuki Kojima

Department of Immune Regulation, Tokyo
Medical and Dental University, Tokyo, Japan.

Novel CD200 homologues iSEC1 and iSEC2 are gastrointestinal secretory cell-specificligands of inhibitory receptor CD200R

Dec. 14(Thu.), 2017

Odd Number / 16:00-17:00, Exhibition
Mucosal-Skin Immunity-2
Even Number / 17:00-18:00 Hall

Koji Hase

Gyohei Egawa

100542 2-F-W22-11-P

Poster Presentation

Masashi Kajita

Institute of Industrial Science, The University ofTokyo, Japan

Affinity amplification for selective T cell response to specific ligands

Dec. 13
16:00-17:00(Wed.), 2017

Exhibition T cell-1: T cell development
and repertoire selection
Hall

TaishinAkiyamaTakeshi Nitta

100543 1-I-W18-9-O/P

Presentation: 7min,
Discussion: 3min

Harada Yasuyo

Research Institute for Biomedical Science, Tokyo <strong>Role of follicular helper T cells and TH2 cells in IgE mediated
University of Science, Chiba, Japan</strong><strong>active cutaneous anaphylaxis</strong>

Dec. 12(Tue.), 201714:55-16:15

Room I

Helper T cells

Masakatsu
YAMASHITA

Motoko Y.
KIMURA

100544 2-B-W20-12-O/P

Presentation: 7min,
Discussion: 3min

Takuto Ohki

<strong>Symmetric-Gateway Reflex, which develops </strong><strong>symmetrical
Division of Psychoimmunology, Institute for
Genetic Medicine, Graduate School of Medicine, inflammation between joints is induced by the specific sensory pathway in a rheumatoid
Hokkaido University
arthritis model</strong>

Dec. 13
14:25-15:45(Wed.), 2017

Room B

Systemic autoimmune
disease (1)Hitoshi
Kohsaka

Shinsuke
Yasuda100545 1-C-W6-9-O/P

Presentation: 7min,
Discussion: 3min

Namiko Okabe

Department of Rheumatology and Clinical
Immunology, Graduate School of Medicine,
Kyoto University, Kyoto, Japan

Myelin basic protein promotes experimental arthritis via non-T cells.

Dec. 12(Tue.), 201714:55-16:15

Room C

Tissue-specific immune
diseases II

NaozumiIshimaru

Hiroto Tsuboi

100546 3-H-W40-25-P

Poster Presentation

Yuya TABAKAWA

Department of Immune Regulation, Tokyo
Medical and Dental University Graduate School,
Tokyo, Japan

Histamine plays a critical role in acquired protective immunity against tick infestation

Dec. 14(Thu.), 2017

Odd Number / 16:00-17:00, Exhibition
Granulocyte & Mast cells
Even Number / 17:00-18:00 Hall

Atsuhito Nakao

YosukeKurashima100547 1-I-W18-14-P

Poster Presentation

Yuriko Tanaka

Department of Molecular Immunology, Toho
University School of Medicine, Tokyo, Japan

The presence of T cells with both Th1 and Th2 characteristics in mice

Dec. 12(Tue.), 2017

Odd Number / 16:30-17:30, Exhibition
Helper T cells
Even Number / 17:30-18:30 Hall

Masakatsu
YAMASHITA

Motoko Y.
KIMURA

100548 1-I-W17-20-P

Poster Presentation

Morita Kentaro

Department of Immunology and Parasitology,
School of Medicine, University of Occupational
and Environmental Health, Japan, Kitakyushu,
Japan

Effect of triterpenoid anticancer drug CuD on peripheral blood lymphocytes from a patientwith recurrent ATLL

Dec. 12(Tue.), 2017

Odd Number / 16:30-17:30, Exhibition
Human Immunology
Even Number / 17:30-18:30 Hall

Koji Yasutomo Keishi Fujio

100549 2-H-W24-7-O/P

Presentation: 7min,
Discussion: 3min

Fumiji Saito

Research Institute for Microbial Diseases, Osaka <strong>Immune evasion of <em>Plasmodium falciparum</em> by RIFIN
University, Osaka, Japan</strong><strong>via inhibitory receptor</strong>

Dec. 13
14:25-15:45(Wed.), 2017

Room H

Immune response to parasite
infections

Yoichi
Maekawa

Masahiro
Yamamoto

100550 2-I-W25-13-O/P

Presentation: 7min,
Discussion: 3min

Yuta Shimizu

Department of Immunochemistry, ResearchInstitute for Microbial Disease, Osaka University, Chemical compounds that specifically inhibit aberrant MHC class II expression
Laboratory of ImmunochemistryDec. 13
14:25-15:45(Wed.), 2017

Room I

Dendritic cells andMacrophages-1: Organspecific Immune Tolerance

Satoshi Ishido

Kenichi Asano

100551 1-G-W13-9-O/P

Presentation: 6min,
Discussion: 2min

Tatsuya Shishido

Department of Immunochemistry, Research
Crucial role of CD74 in hematopoietic cell differentiation
Institute for Microbital Disease, Osaka University

Dec. 12(Tue.), 201713:20-14:40

Room G

Hematopoiesis and immune
environments

TakashiNagasawa

HitoshiTakizawa

100552 3-G-W38-7-O/P

Presentation: 7min,
Discussion: 4min

Yuki Sasagawa

Laboratory of Immunochemistry, WPI
Immunology Frontier Reseach Center, Osaka
University, Osaka, Japan

Antiphospholipid antibody recognizes &beta;2GPI complexed with HLA class II molecules
via its domain V

Dec. 14(Thu.), 201712:50-14:10

Room G

Systemic autoimmune
disease (2)Yoshiya Tanaka

Masayuki
Nishide100553 1-A-W2-17-P

Poster Presentation

Narumi Suzuki

Laboratory for Cytokine Regulation,ResearchCenter for Integrative Medical Science ,RIKEN
Yokohama Institute,Yokohama,japan

E4BP4/NFIL-3 is a critical transcription factor to control TH2 attraction into inflammation site Dec. 12
during chronic allergic responses.
(Tue.), 2017

Tomohiro
YoshimotoRyoji Yagi

100554 2-G-W23-10-P

Poster Presentation

Tsukasa Ugajin

Tokyo Medical and Dental University, Tokyo,
Japan<strong>Bilirubin oxidation derived from oxidative stress is associated with disease severityof atopic dermatitis</strong>

Dec. 13
16:00-17:00(Wed.), 2017

Exhibition Allergy-3 : Allergic dermatitis,
food allergy and allergic
Kenji IzuharaHallconjunctivitis

Presentation: 7min,
Discussion: 3min

Division of Molecular Immunology, Institute for100555 2-I-W25-12-O/P

Matsumoto Minoru Enzyme Research, Tokushima University,
Tokushima, Japan

Transgenic human AIRE expression in NOD acquired resistance to the diabetes due to theimpaired presentation of self-antigens in the pancreas

Dec. 13
14:25-15:45(Wed.), 2017

Room I

100556 3-I-W43-2-P

Poster Presentation

Yuki TABATA

Research Institute for Biomedical Sciences,
Tokyo University of Science, Chiba, Japan<strong>IL-2 production is negatively regulated by free fatty acid receptor 2 (Ffar2)
mediated signaling.</strong>

Dec. 14(Thu.), 2017

Odd Number / 16:00-17:00, Exhibition
T cell-3 : T cell function
Even Number / 17:00-18:00 Hall

Harumi Suzuki Ei Wakamatsu

100557 3-I-W43-3-P

Poster Presentation

Masanobu Kimura

Department of Microbiology and Immunology,<strong>TRAF2 and TRAF5 binding to the signal transducing receptor gp130 inhibit JAK1
Tohoku University Graduate School of Medicine,
activation in the IL-6-receptor signaling complex</strong>
Sendai, Japan

Dec. 14(Thu.), 2017

Odd Number / 16:00-17:00, Exhibition
T cell-3 : T cell function
Even Number / 17:00-18:00 Hall

Harumi Suzuki Ei Wakamatsu

100558 3-F-W37-13-P

Poster Presentation

Sachi Tanaka

Graduate School of Agriculture, Shinshu
University, Nagano, Japan

Dec. 14(Thu.), 2017

Odd Number / 16:00-17:00, Exhibition
Mucosal-Skin Immunity-3
Even Number / 17:00-18:00 Hall

Eiji Umemoto

Jun Kunisawa

100559 3-F-W36-7-P

Poster Presentation

Masako Kohyama

Department of Immunochemistry, Research
Intestinal epithelial homeostasis regulated by CD74
Institute for Microbial Diseases, Osaka University

Dec. 14(Thu.), 2017

Odd Number / 16:00-17:00, Exhibition
Mucosal-Skin Immunity-2
Even Number / 17:00-18:00 Hall

Koji Hase

Gyohei Egawa

100560 3-F-W37-16-P

Poster Presentation

Naoki Takemura

Department of Mucosal Immunology, School of
Medicine, Chiba University, Chiba, Japan

Dec. 14(Thu.), 2017

Odd Number / 16:00-17:00, Exhibition
Mucosal-Skin Immunity-3
Even Number / 17:00-18:00 Hall

Eiji Umemoto

Jun Kunisawa

Caloric restriction ameliorates dextran sulfate sodium-induced colitis in micePrime-boost vaccination with CpG ODN and curdlan strongly induces both systemic andmucosal immunity

25 / 30

Odd Number / 16:30-17:30, Exhibition Allergy-2: Upper airway
allergic inflammation andEven Number / 17:30-18:30 Hall
allergic responses

Dendritic cells andMacrophages-1: Organspecific Immune Tolerance

Satoshi Ishido

Tomohiro
YoshimotoKenichi Asano

The 46th Annual Meeting of The Japanese Society for Immunology
Submission ID

Program No.

Oral Presentation Time

1st Author

Submission ID orderAffiliation

100561 3-I-W42-1-P

Poster Presentation

Manabu Inobe

Institute of Medical, Pharmaceutical and Health
Sciences, Kanazawa University, Kanazawa,
Japan

100562 3-A-W26-10-O/P

Presentation: 10min,
Discussion: 3min

Kazuki Kishida100563 3-I-W43-11-O/P

Presentation: 7min,
Discussion: 3min

100564 3-A-W27-15-O/P

Title

Date

Time

Venue

Session Title

Dec. 14(Thu.), 2017

Odd Number / 16:00-17:00, Exhibition
T cell-2 : T cell signaling
Even Number / 17:00-18:00 Hall

Department of Immunochemistry, Research<strong>Antigen-specific immune regulation mediated by TCR-like antibodies</strong>
Institute for Microbial Diseases, Osaka University

Dec. 14(Thu.), 201712:50-14:10

Room A

Akio Ohta

Department of Molecular Medicine, Foundationfor Biomedical Research and Innovation, Kobe,
Japan

Transient hypoxia persistently inhibits T cell activation

Dec. 14(Thu.), 201714:25-15:45

Presentation: 10min,
Discussion: 3min

Reiko Takahashi

Research Institute Nozaki Tokushukai, Daitou,
Japan

Inhibition of melanoma proliferation by immunologic mechanism including the plasticity of
SOCS1 deficient regulatory T cells

Dec. 14(Thu.), 2017100565 1-F-W11-4-O/P

Presentation: 9min,
Discussion: 2min

Shime Hiroaki

Department of Immunology,?Nagoya City
Toll-like receptor 2 ligand and interferon-&gamma; suppress anti-tumor T cell responses by
University Graduate School of Medical Sciences,enhancing the immunosuppressive activity of monocytic myeloid-derived suppressor cells
Nagoya, Japan

100566 3-B-W29-1-O/P

Presentation: 11min,
Discussion: 2min

Takashi Ebihara

100567 1-G-W13-22-P

Poster Presentation

Toshihiro Komatsu Kochi University, Kochi, Japan

100568 1-G-W13-23-P

Poster Presentation

Junya Ohtake

100569 1-I-W17-12-P

Poster Presentation

100570 3-A-W27-12-P

Chair1Chair2

SatoshiMatsudaTadashiYokosuka

Tolerance and immune
suppression -1

Taku Okazaki

Shunsuke
Chikuma

Room IT cell-3 : T cell function

Harumi Suzuki Ei Wakamatsu

14:25-15:45

Room A

Tolerance and immune
suppression -2

Naganari
OhkuraDec. 12(Tue.), 201713:20-14:40

Room F

Combination cancer
Hiroyoshi
immunothrapy -beyond
immune checkpoint inhibitors- Nishikawa

Laboratory for Transcriptional Regulation, RIKEN Runx proteins suppress constitutive activity of ILC2 and prevent ILC2 exhaustion afterCenter for Integrative Medical Sciences
activation

Dec. 14(Thu.), 201714:25-15:45

Room B

Innate Lymphocyte-2(ILC1,2,3)

Department of Immunology, School of Medicine, Extravasation of CTLs occurs by recognizing the MHC-peptide complexes cross-presented

by vascular endothelial cells.

Dec. 12(Tue.), 2017

Cancer Vaccine Center, Kanagawa Cancer
Center, Yokohama, Japan<strong>Comprehensive analysis of immunological tumor environment in colorectal
cancer</strong>

Hirofumi Shibata

Department of Pediatrics, Kyoto University
Graduate School of Medicine, Kyoto, Japan

A novel human Cytotoxic Lymphocyte-based functional assays for primary hemophagocytic
lymphohistiocytosis

Poster Presentation

YUN GUO

100571 2-C-W21-8-O/P

Presentation: 10min,
Discussion: 3min

100572 3-C-W31-18-P

CD8<sup>+</sup> T cells are less dependent on Erk to proliferate compared with
CD4<sup>+</sup> T cells

Takashi Sekiya
Yoshihiro
Hayakawa

SusumuNAKAE

Shinichiro
SAWA

Odd Number / 16:30-17:30, Exhibition Hematopoiesis and immune
environments
Even Number / 17:30-18:30 Hall

TakashiNagasawa

HitoshiTakizawa

Dec. 12(Tue.), 2017

Odd Number / 16:30-17:30, Exhibition Hematopoiesis and immune
environments
Even Number / 17:30-18:30 Hall

TakashiNagasawa

HitoshiTakizawa

Dec. 12(Tue.), 2017

Odd Number / 16:30-17:30, Exhibition
Human Immunology
Even Number / 17:30-18:30 Hall

Koji Yasutomo Keishi Fujio

Department of Immunology, Graduate School of
Biomedical &amp; Health Sciences, Hiroshima
Ubiquitin-modifying enzyme A20 plays a role in regulatory T cells
University, Hiroshima, Japan

Dec. 14(Thu.), 2017

Odd Number / 16:00-17:00, Exhibition Tolerance and immune
suppression -2
Even Number / 17:00-18:00 Hall

Naganari
OhkuraTakashi Sekiya

Raul Vizcardo

Surgery Branch, National Cancer Institute,
Developing the next generation of iPSC cell-based immunotherapies
National Institutes of Health, Bethesda MD, USA

Dec. 13
14:25-15:45(Wed.), 2017

Hiroaki Ikeda

Koji Tamada

Poster Presentation

Noriko Mutoh

Department of Oral Interdisciplinary Medicine,
Division of Pulp Biology, Kanagawa Dental
university, Yokosuka, Japan

Dec. 14(Thu.), 2017

Odd Number / 16:00-17:00, Exhibition Dendritic cells andTsuneyasu
Macrophages-3: Inflammatory
Even Number / 17:00-18:00 Hall
KaishoResponses

100573 3-G-W38-8-O/P

Presentation: 7min,
Discussion: 4min

Satoko Morikami

Department of Obstetrics and Gynecology, Kobe
Prothrombin complexed with HLA class II molecules is an autoantibody target in
University Graduate School of Medicine, Hyogo,
antiphospholipid syndrome
Japan

Dec. 14(Thu.), 201712:50-14:10

Room G

100574 3-D-W33-1-O/P

Presentation: 7min,
Discussion: 3min

Okumura Genki

Department of Immunology, Faculty of medicine,The role of soluble CD155 in tumor immune response and metastasis
University of Tsukuba

Dec. 14(Thu.), 201714:25-15:45

Room D

100575 3-D-W33-9-O/P

Presentation: 7min,
Discussion: 3min

Satoshi Ueha

Department of Molecular Preventive Medicine,
Graduate School of Medicine, The University ofTokyo, Tokyo, JapanTCR sequencing reveals the generation and expansion of tumor-specific CD8<sup>+</sup>T cell clones after anti-CD4 antibody treatment in tumor-bearing mice

Dec. 14(Thu.), 201714:25-15:45

Room D

100576 1-C-W6-11-O/P

Presentation: 7min,
Discussion: 3min

Soo-hyun Chung

Center for Animal Disease Models, ResearchInstitute for Biomedical Sciences, Tokyo
University of Science, Noda, Japan

Truncated glycan and C-type lectin ; a new therapeutic target for autoimmune arthriti

Dec. 12(Tue.), 201714:55-16:15

Room C

100577 1-E-W10-2-P

Poster Presentation

Masayuki
UmemuraTropical Biosphere Research Center, Universityof the Ryukyus, Okinawa, Japan

Involvement of IL-17A-producing TCR &gamma;&delta;<sup>+</sup> T cells in late
protective immunity against pulmonary <em>Mycobacterium tuberculosis </em>infection

Dec. 12(Tue.), 2017

Odd Number / 16:30-17:30, Exhibition Immune response to
mycobacteial and fungal
Even Number / 17:30-18:30 Hall
infections

100578 3-A-W27-10-O/P

Presentation: 10min,
Discussion: 3min

Chikako
Shimokawa

Department of Parasitology, Graduate School of
Medicine, Gunma University, Gunma

Suppression of type 1 diabetes in mice infected with an intestinal nematodeDec. 14(Thu.), 201714:25-15:45

100579 1-E-W10-11-P

Poster Presentation

Yuki SATO

Medical Microbiology, Mycology andEffect of Mincle-deficiency on the host immune response against <em>Cryptococcus
Immunology, Tohoku University Graduate School
neoformans</em> infectionof Medicine, Miyagi, Japan

Dec. 12(Tue.), 2017

Odd Number / 16:30-17:30, Exhibition Immune response to
mycobacteial and fungal
Even Number / 17:30-18:30 Hall
infections

100580 2-H-W24-11-O/P

Presentation: 7min,
Discussion: 3min

Piyarat Srinontong

Department of Parasitology and Infectious
Diseases, Gifu University Graduate School of
Medicine, Gifu, Japan

Regulation of Visceral Leishmaniasis by Secreted Immunoglobulin Deficiency

Dec. 13
14:25-15:45(Wed.), 2017100581 3-E-W34-14-P

Poster Presentation

Yangyang Feng

Department of Immunology, Medical ResearchInstitute, Tokyo Medical and Dental University<strong>Role of NADPH oxidases in BCR ligation-induced ROS production andactivation</strong>

Dec. 14(Thu.), 2017100582 3-I-W43-14-O/P

Presentation: 7min,
Discussion: 3min

Hisako Akatsuka

Department of Host Defense Mechanism, Tokai AMBRA1 is involved in T cell receptor-mediated metabolic reprogramming through ATG7University School. of Medicine, Kanagawa Japan independent pathway

Dec. 14(Thu.), 2017

Innate immune response induce the dentin regeneration in dental pulp

26 / 30

Room C

Cell therapy

Rikinari
Hanayama

Yoshiya Tanaka

Masayuki
NishideToshihiko
Torigoe

Yoshihiro
Hayakawa

Toshihiko
Torigoe

Yoshihiro
Hayakawa

NaozumiIshimaru

Hiroto Tsuboi

Kazuyoshi
Kawakami

Hiromitsu Hara

Naganari
OhkuraTakashi Sekiya

Kazuyoshi
Kawakami

Hiromitsu Hara

Yoichi
Maekawa

Masahiro
Yamamoto

Odd Number / 16:00-17:00, Exhibition B cell development andfunction
Even Number / 17:00-18:00 Hall

Yoshiteru
Sasaki

Reiko Shinkura

14:25-15:45

Harumi Suzuki Ei Wakamatsu

Room A

Room H

Room I

Systemic autoimmune
disease (2)Tumor immunology-2(Immunosuppression andmodulation in tumor
immunity)
Tumor immunology-2(Immunosuppression andmodulation in tumor
immunity)
Tissue-specific immune
diseases II

Tolerance and immune
suppression -2

Immune response to parasite
infections

T cell-3 : T cell function

The 46th Annual Meeting of The Japanese Society for Immunology
Submission ID

Program No.

Oral Presentation Time

1st Author

Submission ID orderAffiliation

Title

Date

Time

Venue

Session Title

Exhibition Allergy-3 : Allergic dermatitis,
food allergy and allergicHallconjunctivitis

Chair1Chair2

Kenji Izuhara

Tomohiro
Yoshimoto

Eiji Umemoto

Jun Kunisawa

100583 2-G-W23-11-P

Poster Presentation

Masayuki Kitajima

Depertment of Immunology and Pathology,
Research Institute National Center for Global
Health and Medicine

100584 3-F-W37-9-P

Poster Presentation

Hisashi Ueta

Department of Anatomy (Macro), Dokkyo
Medical University, Tochigi, Japan

Peyer&rsquo;s patch functions as a transition site for rapid recirculation of lymphocytes
during gut immunosurveillance: multicolor immunohistochemical study

Dec. 14(Thu.), 2017

Odd Number / 16:00-17:00, Exhibition
Mucosal-Skin Immunity-3
Even Number / 17:00-18:00 Hall100585 3-E-W35-4-O/P

Presentation: 7min,
Discussion: 3min

Wataru Ise

Immunology Frontier Research Center, Osaka
University, Osaka, JapanThe heightened T-B interaction associates with plasma-prone germinal center B cells

Dec. 14(Thu.), 201714:25-15:45

Room E

Germinal center reaction andplasma cells

Masaki Hikida

Wataru Ise

100587 1-D-W7-7-O/P

Presentation: 6min,
Discussion: 2min

Takeharu
Minamitani

Laboratory of Infectious Diseases and Immunity,
T cell and NK cell-mediated immune surveillance interferes with Epstein-Barr virus LMPNational Institutes of Biomedical Innovation,induced lymphomagenesis in germinal center B cells
Health, and Nutrition, Ibaraki, Osaka, Japan

Dec. 12(Tue.), 201713:20-14:40

Room D

Virus infection-1

Taro Kawai

Mitsutoshi
Yoneyama

100588 1-C-W5-1-O/P

Presentation: 7min,
Discussion: 3min

Ben Raveney

Department of Immunology, National Institute of Eomes-positive cytotoxic T helper cells: a new pathogenic immune cell subset in secondary
Neuroscience, NCNP, Kodaira, Tokyo, Japan
progressive multiple sclerosis?

Dec. 12(Tue.), 201713:20-14:40

Room C

Tissue-specific immune
diseases I

Mitsuru
Matsumoto

Daisuke
Kamimura

100589 3-A-W27-4-O/P

Presentation: 10min,
Discussion: 3minYumi YamashitaKanemaru

Department of Immunology, Faculty of Medicine,
DNAM-1 limits Treg cell function via TIGIT-dependent manner
University of Tsukuba, Tsukuba, Ibaraki, Japan

Dec. 14(Thu.), 201714:25-15:45

Room A

Tolerance and immune
suppression -2

Naganari
OhkuraTakashi Sekiya

100590 1-A-W1-15-P

Poster Presentation

Masashi Ikutani

Department of Immune Regulation, ResearchInstitute, National Center for Global Health andMedicine, Chiba, Japan

Chronic IL-33-induced inflammation results in pulmonary arterial hypertrophy

Dec. 12(Tue.), 2017

Odd Number / 16:30-17:30, Exhibition Allergy-1 : Lower airway
allergic inflammation
Even Number / 17:30-18:30 Hall

Kenji Izuhara

Koubun Yasuda

100591 1-H-W16-16-P

Poster Presentation

Kei Matsuno

Department of Respiratory Medicine, Juntendo
University School of Medicine, Tokyo, JapanTWEAK enhances epithelial mesenchymal transition and chemokine production in humanbronchial epithelial cells

Dec. 12(Tue.), 2017

Odd Number / 16:30-17:30, Exhibition
Takayuki
Cytokines and chemokines-2
Even Number / 17:30-18:30 Hall
Yoshimoto

100592 2-F-W22-4-P

Poster Presentation

Honomi Saito

Department of Molecular and Cellular
Immunology, Shinshu University School of
Medicine, Matsumoto, Japan

Forced over-expression of T-bet transcription factor in thymocytes inhibits DN to DPtransition

Dec. 13
16:00-17:00(Wed.), 2017

Exhibition T cell-1: T cell development
and repertoire selection
Hall

TaishinAkiyamaTakeshi Nitta

100593 2-B-W20-16-P

Poster Presentation

Chiharu Tomi

Department Immunology, National Institute of
Neuroscience, NCNP, Kodaira, Tokyo, Japan

Roles of NR4A2 for pathogenic properties of autoreactive T helper cells in lupus-prone
mice.

Dec. 13
16:00-17:00(Wed.), 2017

Exhibition Systemic autoimmune
disease (1)Hall

Hitoshi
Kohsaka

Shinsuke
Yasuda100594 3-I-W42-10-O/P

Presentation: 7min,
Discussion: 3min

Yuji Kamioka

Department of Molecular Genetics, Institute of
Biomedical Science, Kansai Medical University,
Osaka, Japan

Roles of Rap1 and Kindlin-3 in lymphocyte homing to peripheral lymph nodes

Dec. 14(Thu.), 201712:50-14:10

Room I

SatoshiMatsudaTadashiYokosuka100595 3-A-W26-3-P

Poster Presentation

Ami Takahashi

Laboratory of Biomolecular Science, Faculty of
Pharmaceutical Sciences, Hokkaido University,
Hokkaido, Japan

HLA-G2 gives immunosuppressive effects to human monocytes and dendritic cells

Dec. 14(Thu.), 2017

Odd Number / 16:00-17:00, Exhibition Tolerance and immune
suppression -1
Even Number / 17:00-18:00 Hall

Taku Okazaki

Shunsuke
Chikuma

100596 2-F-W22-16-P

Poster Presentation

Takeyuki Shimizu

Department of Immunology, School of Medicine, Construction of a TAP deficient HLA class I-binding assay system with the use of
Kochi University, Kochi, Japan
CRISPR/Cas9 system

Dec. 13
16:00-17:00(Wed.), 2017

Exhibition T cell-1: T cell development
and repertoire selection
Hall

TaishinAkiyamaTakeshi Nitta

100597 3-B-W28-3-P

Poster Presentation

Maia Inoue

Department of Immunology, Graduate School of
Medicine and Faculty of Medicine, The University A critical epigenetic regulator of early iNKT cell developmentof Tokyo, Tokyo, Japan

Dec. 14(Thu.), 2017

Odd Number / 16:00-17:00, Exhibition Innate Lymphocyte-1 (NKT,
MAIT, gdT, NK)
Even Number / 17:00-18:00 Hall

Kensuke
ShibataKazuyaIWABUCHI

100598 3-E-W35-5-O/P

Presentation: 7min,
Discussion: 3min

Atsuko Kayaba

Department of Experimental Immunology,
Institute of Development, Aging and Cancer,
Tohoku University, Sendai, Japan

PIR-B suppresses IL-6 secretion from mesenchymal stem cells and regulates theimmunoglobulin production of plasma cells.

Dec. 14(Thu.), 201714:25-15:45

Masaki Hikida

Wataru Ise

100599 3-D-W32-15-P

Poster Presentation

Masaki Tamiya

Division of Cell signaling, Institute for Advanced
Medical Research, Keio University school of
Medicine

Reversal of anti-PD-1/PD-L1 therapy resistance by modulation of tumor-associatedmacrophages using CSF-1 receptor blockade

Dec. 14(Thu.), 2017

Odd Number / 16:00-17:00, Exhibition Tumor immunology-1 (Tumor Yutaka
antigens, antigen presenting
Even Number / 17:00-18:00 Hall
Kawakami
cells, anti-tumor T cells)

Hirokazu
Matsushita

100600 1-D-W8-7-O/P

Presentation: 6min,
Discussion: 2.5min

Daichi Yamasoba

Laboratory of Infection and Prevention, Institutefor Frontier Life and Medical Sciences, Kyoto
University, Kyoto, Japan

Identification of a novel HIV-1 restriction factor which selectively degrades viral transcripts.

Dec. 12(Tue.), 201714:55-16:15

Room D

Virus infection-2

Takashi Fujita

HiroyukiOshiumi100601 3-F-W36-17-O/P

Presentation: 7min,
Discussion: 3min

Saeko Nakajima

Department of Dermatology, Kyoto University
Graduate School of Medicine<em>Candida albicans</em> skin colonization exacerbates the inflammation of murine
psoriasis-like dermatitis

Dec. 14(Thu.), 201712:50-14:10

Room F

Mucosal-Skin Immunity-2

Koji Hase

Gyohei Egawa

100602 1-C-W5-12-P

Poster Presentation

AKIBA Yasushi

Department of Molecular Immunology, Toho
University School of Medicine, Tokyo, Japan

Nuclear protein SATB1 is required for development of experimental autoimmune
encephalomyelitis

Dec. 12(Tue.), 2017

Odd Number / 16:30-17:30, Exhibition Tissue-specific immune
diseases I
Even Number / 17:30-18:30 Hall

Mitsuru
Matsumoto

Daisuke
Kamimura

100603 1-E-W10-1-O/P

Presentation: 7min,
Discussion: 3min

Ei'ichi Iizasa

Department of Immunology, Field of Infection
and Immunity, Graduate School of Medical and
Dental Sciences, Kagoshima University,
Kagoshima

Two ITAM-coupled receptors recognizing Mycobacterial mycolic acid-containing lipids andhaving the different roles.

Dec. 12(Tue.), 201714:55-16:15

Room E

Immune response to
mycobacteial and fungal
infections

Kazuyoshi
Kawakami

Hiromitsu Hara

100604 3-H-W40-20-O/P

Presentation: 7min,
Discussion: 3min

Shota Toyoshima

Allergy and Immunology Research Project Team,
Comparison of microRNA in human mast cell-derived exosomes in innate and acquiredCenter for Institutional Research and Medical
Education, Nihon University School of Medicine, immunity
Tokyo, Japan

Dec. 14(Thu.), 201712:50-14:10

Room H

Granulocyte & Mast cells

Atsuhito Nakao

YosukeKurashima

100605 2-G-W23-12-P

Poster Presentation

Michiyuki Kasai

Department of Immunology, School of Medicine, Application with nano-sized cyanoacryl particles ameliorates experimental dermatitis throughKochi University,
the bacteriocidal activity

Dec. 13
16:00-17:00(Wed.), 2017

Role of TSLPR on CD4 T cells in exacerbation of skin inflammation.

Dec. 13
16:00-17:00(Wed.), 201727 / 30

Room ET cell-2 : T cell signaling

Germinal center reaction andplasma cells

Exhibition Allergy-3 : Allergic dermatitis,
food allergy and allergic
Kenji IzuharaHallconjunctivitis

Takashi
Kobayashi

Tomohiro
YoshimotoThe 46th Annual Meeting of The Japanese Society for Immunology
Submission ID

Program No.

Oral Presentation Time

1st Author

Submission ID orderAffiliation

Title

Date

Time

Venue

Chair1Chair2

Dec. 13
16:00-17:00(Wed.), 2017

Exhibition Dendritic cells andMacrophages-1: OrganHall
specific Immune Tolerance

Satoshi Ishido

Kenichi Asano

Room I

Dendritic cells andMacrophages-1: Organspecific Immune Tolerance

Satoshi Ishido

Kenichi Asano

Session Title

100606 2-I-W25-15-P

Poster Presentation

Kouta Fujikura

Chiba Institute of Technology, Graduate Schoolof Engineering, Department of Life andEnvironmental Sciences, Narashino,Japan

100607 2-I-W25-4-O/P

Presentation: 7min,
Discussion: 3min

Keita Aoi

Department of Immunology and Cell Biology,
Graduate School of Medicine / Frontier
Biosciences, Osaka University, Osaka, Japan

Oral mucosa-specific macrophage subsets contribute to tolerance induction in sublingual
immunotherapy

Dec. 13
14:25-15:45(Wed.), 2017

100608 3-F-W36-8-P

Poster Presentation

Terufumi Kubo

Department of Pathology, Sapporo Medical
University School of Medicine, Sapporo, Japan

Differential bronchial epithelial response regulated by deltaNp63: a potential mechanism
explaining chronicity of asthma

Dec. 14(Thu.), 2017

Odd Number / 16:00-17:00, Exhibition
Mucosal-Skin Immunity-2
Even Number / 17:00-18:00 Hall

Koji Hase

Gyohei Egawa

100609 3-I-W42-4-O/P

Presentation: 7min,
Discussion: 3min

Ryunosuke Muro

Graduate School of Medicine and Faculty of
Medicine, The University of Tokyo, Japan

Control of proinflammatory &gamma;&delta;T cell development by linage-specific TCR
signaling pathway

Dec. 14(Thu.), 201712:50-14:10

Room IT cell-2 : T cell signaling

SatoshiMatsudaTadashiYokosuka

100610 3-E-W35-3-O/P

Presentation: 7min,
Discussion: 3min

Kei Haniuda

Research Institute for Biomedical Sciences,
Tokyo University of Science, Chiba, Japan

Germinal center B cell development by glycolysis and mitochondrial metabolism

Dec. 14(Thu.), 201714:25-15:45

Room E

Germinal center reaction andplasma cells

Masaki Hikida

Wataru Ise

100611 1-H-W15-16-P

Poster Presentation

Numasaki Muneo

Tohoku University Hospital, Sendai, Japan

IL-32 promotes the cell growth of malignant methothelioma

Dec. 12(Tue.), 2017

Odd Number / 16:30-17:30, Exhibition
Masaaki
Cytokines and chemokines-1
Even Number / 17:30-18:30 Hall
Murakami

100612 3-D-W33-13-P

Poster Presentation

Yoshinori
TAKAHASHI

Department of Pulmonary and Critical Care
Medicine, Mie University Hospital, Japan

Biomarkers including circulating PD-L1 and PD-1 in human (L858R) EGFR mutant
transgenic mice with lung cancer

Dec. 14(Thu.), 2017

Odd Number / 16:00-17:00, Exhibition (Immunosuppression andmodulation in tumor
Even Number / 17:00-18:00 Hall

100613 3-E-W34-6-O/P

Presentation: 7min,
Discussion: 3min

Adachi Takahiro

Department of Immunology, Medical ResearchInstitute, Tokyo Medical and Dental University,
Tokyo, Japan

Intravital imaging of Ca<sup>2+</sup> signals in lymphocytes of the Ca<sup>2+</sup>biosensor YC3.60 transgenic mice

Dec. 14(Thu.), 201712:50-14:10

Room E

100614 1-B-W3-1-O/P

Presentation: 7min,
Discussion: 2min

Ryota Sato<strong>Requirement of glycosylation machinery in Toll-like receptor responses revealed by
Division of Innate Immunity, The Institute ofMedical Science, The University of Tokyo, Japan CRISPR/Cas9 screening </strong>

Dec. 12(Tue.), 201713:20-14:40

Room B

100615 3-I-W43-10-P

Poster Presentation

Yoichi Maekawa

Department of Parasitology and Infectious
Diseases, Gifu University Graduate School of
Medicine, Gifu, Japan

Dec. 14(Thu.), 2017

Odd Number / 16:00-17:00, Exhibition
T cell-3 : T cell function
Even Number / 17:00-18:00 Hall

Harumi Suzuki Ei Wakamatsu

100616 3-H-W40-21-O/P

Presentation: 7min,
Discussion: 3min

Jun-ichiKashiwakura

Department of Immunology, Graduate School of
Pharmaceutical Sciences, Hokkaido University, STAP-2 is an adopter molecule to positively regulate basophil activation
Hokkaido, Japan

Dec. 14(Thu.), 201712:50-14:10

Room H

Granulocyte & Mast cells

Atsuhito Nakao

100617 1-F-W11-9-O/P

Presentation: 9min,
Discussion: 2min

kagawa Masaki

Division of Cellular Signaling Institute, forAdvanced Medical Research, Keio University
School of Medicine

Immunomodulation of ovarian clear cell carcinoma by targeting HNF-1&beta;-NF-kB-IL6
pathway enhances anti-tumor immunity

Dec. 12(Tue.), 201713:20-14:40

Room F

Combination cancer
Hiroyoshi
immunothrapy -beyond
immune checkpoint inhibitors- Nishikawa

100618 1-C-W6-2-O/P

Presentation: 7min,
Discussion: 3min

Ikuma Nakagawa

Division of Psychoimmunology, Institute for
Genetic Medicine, Hokkaido University,
Hokkaido, Japan<strong>Primary Sj&ouml;gren&rsquo;s syndrome-associated gene<em> STF1</em>
regulates inflammation via </strong><strong>NF-</strong><strong>k</strong><strong>B
pathway</strong>

Dec. 12(Tue.), 201714:55-16:15

Room C

Tissue-specific immune
diseases II

NaozumiIshimaru

Hiroto Tsuboi

100619 1-B-W4-6-O/P

Presentation: 7min,
Discussion: 2min

Kiyoharu
Fukushima

Department of Host Defense, Research Institutefor Microbial Diseases (RIMD), Osaka University, Screening of causative genes for fibrosis development in mice.
Osaka, Japan.

Dec. 12(Tue.), 201714:55-16:15

Room B

Endogenous innate immunity
and inflammation-2

Osamu
Takeuchi

SachikoTakamura(Akashi)

100620 1-I-W18-3-O/P

Presentation: 7min,
Discussion: 3min

Keiko Yasuda

Laboratory of Experimental Immunology, Institutefor Frontier Life and Medical Sciences, Kyoto
Satb1 controls the differentiation and terminal effector function of Th17 cells
University, Kyoto, Japan

Dec. 12(Tue.), 201714:55-16:15

Room I

Helper T cells

Masakatsu
YAMASHITA

Motoko Y.
KIMURA

100621 3-F-W36-4-P

Poster Presentation

Ichiro Takahashi

Department of Mucosal Immunology, Dental
School, Hiroshima University, Hiroshima, Japan

Metabolic demand of colonic macrophages for symbiotic and cytosolic colonization by nonlymphoid tissue resident commensal bacteria

Dec. 14(Thu.), 2017

Odd Number / 16:00-17:00, Exhibition
Mucosal-Skin Immunity-2
Even Number / 17:00-18:00 Hall

Koji Hase

Gyohei Egawa

100622 3-C-W30-3-O/P

Presentation: 7min,
Discussion: 3minNobuyuki Onai

Department of Immunology, Kanazawa Medical
University, Ishikawa, Japan

Regulation of pDC development by graded expression of E2-2

Dec. 14(Thu.), 201712:50-14:10

100623 2-H-W24-9-P

Poster Presentation

Mizuho Tabata

Department of Parasitology and Infectious
Diseases, Gifu University Graduate School of
Medicine, Gifu, Japan

Infection of parasitic nematode ameliorates imiquimod (IMQ)-induced psoriasis

100624 3-F-W36-18-O/P

Presentation: 7min,
Discussion: 3min

Gyohei Egawa

Department of Dermatology, Kyoto University
Graduate School of Medicine, Kyoto, Japan

100625 1-H-W15-9-O/P

Presentation: 6min,
Discussion: 2min

Hironao Suzuki

100626 3-D-W32-6-O/P

Presentation: 7min,
Discussion: 3min

100627 1-I-W17-21-P

Poster Presentation

Bioimaging Analysis for Endocytosis of macrophage in inframmation regulated by v-ATPase

Akihiro Kimura

Tumor immunology-2

Toshihiko
Torigoe

Yoshihiro
Hayakawa

B cell development andfunction

Yoshiteru
Sasaki

Reiko Shinkura

Endogenous innate immunity
and inflammation-1

Tatsuya Saitoh Takuya Uehata

immunity)

The immune responses of CD4<sup>+</sup> T cells are affected by hypergravity

YosukeKurashima
Yoshihiro
Hayakawa

Dendritic cells andTomohiko
Macrophages-2: Development
Tamuraand Recognition

Masafumi
Nakayama

Dec. 13
16:00-17:00(Wed.), 2017

Exhibition Immune response to parasite Yoichi
infections
Hall
Maekawa

Masahiro
Yamamoto<strong>Revisiting the concept of CHS response; effector T cells infiltrates into the haptenentry sites and confer long-lasting local memory</strong>

Dec. 14(Thu.), 201712:50-14:10

Room F

Mucosal-Skin Immunity-2

Koji Hase

Gyohei Egawa

Division of Psychoimmunology, Institute for
Genetic Medicine, Hokkaido University,
Hokkaido, Japan<strong>RNA Splicing Mediator 1 (RSM1) regulates inflammation via alternative splicing of
DNA methyltransferase Dnmt3b</strong>

Dec. 12(Tue.), 201713:20-14:40

Room H

Cytokines and chemokines-1

Masaaki
Murakami

Akihiro Kimura

Keisuke Fujii

Department of Immuno-Gene Therapy, Mie
University Graduate School of Medicine, Mie,Japan

Phenotypic and clonality analysis of tumor-reactive CD8<sup>+</sup> T cells among TILs
in human colorectal tumor tissue

Dec. 14(Thu.), 201712:50-14:10

Room D

Tumor immunology-1 (Tumor
antigens, antigen presenting
cells, anti-tumor T cells)

YutakaKawakami

Hirokazu
Matsushita

Shimizu Mikito

Osaka University, Osaka, Japan

Febuxostat Ameliorates Secondary Progressive Experimental Autoimmune
Encephalomyelitis by Restoring Mitochondrial Energy Production in a GOT2-dependent
Manner

Dec. 12(Tue.), 2017

Odd Number / 16:30-17:30, Exhibition
Human Immunology
Even Number / 17:30-18:30 Hall

28 / 30

Room C

Koji Yasutomo Keishi Fujio

The 46th Annual Meeting of The Japanese Society for Immunology
Submission ID

Program No.

Oral Presentation Time

Submission ID order

1st Author

Affiliation

100628 1-D-W8-13-P

Poster Presentation

Kazuya TAKEDA

Faculty of Medicine, Tohoku Medical andPharmaceutical University, Sendai, Miyagi,Japan

100629 1-B-W3-10-P

Poster Presentation

Asuka Inoue

100630 1-C-W6-5-O/P

Presentation: 7min,
Discussion: 3min

Michio Yasunami

Saga-Ken Medical Centre Koseikan, Saga,Japan

100631 1-I-W17-22-P

Poster Presentation

Hiroyuki Yoshitomi Sciences、Kyoto University,

100632 1-B-W3-9-P

Poster Presentation

Yuki Nakajima

100633 3-A-W27-13-P

Poster Presentation

100634 3-D-W33-6-O/P

Title

Date

Time

Venue

Session Title

Chair1Chair2

Dec. 12(Tue.), 2017

Odd Number / 16:30-17:30, Exhibition
Virus infection-2
Even Number / 17:30-18:30 Hall

Research and Development, Sanofi K.K., Tokyo, Immune regulation by inhibitory oligonucleotide ISM ODN for HMGB1 in inflammatoryJapan
disease models

Dec. 12(Tue.), 2017

Odd Number / 16:30-17:30, Exhibition Endogenous innate immunity
Tatsuya Saitoh Takuya Uehata
and inflammation-1
Even Number / 17:30-18:30 Hall

Principal contribution of <em>HLA-DQ</em> alleles, <em>DQB1*06:04</em> and<em>DQB1*03:01</em>, to disease resistance against primary biliary cholangitis in a
Japanese population

Dec. 12(Tue.), 201714:55-16:15

Transcriptional regulation of PD-1<sup>+</sup>CD4<sup>+</sup>T cells under
inflammatory conditions

Dec. 12(Tue.), 2017

Odd Number / 16:30-17:30, Exhibition
Human Immunology
Even Number / 17:30-18:30 Hall

Department of Immunology, Graduate School of
Identificdation of immunogenic endogenous RNA and its inhibitor
Medicine, The University of Tokyo

Dec. 12(Tue.), 2017

Odd Number / 16:30-17:30, Exhibition Endogenous innate immunity
Tatsuya Saitoh Takuya Uehata
and inflammation-1
Even Number / 17:30-18:30 Hall

Yoshihiro Oya

Department of Rheumatology, Allergy &amp;
Clinical Immunology National Hospital
Organization Chiba-East National Hospital ,Chiba, Japan

Allo-specific Foxp3<sup>+</sup>CD4<sup>+ </sup>induced Tregs (allo-iTreg) suppress
specific-alloantigen, but not irrelevant alloantigen in vivo

Dec. 14(Thu.), 2017

Odd Number / 16:00-17:00, Exhibition Tolerance and immune
suppression -2
Even Number / 17:00-18:00 Hall

Presentation: 7min,
Discussion: 3min

Aya Hirata

Department of Immune Medicine, National
Cancer Center Research InstituteEffect of Imatinib mesylate to tumor immunosuppressive microenvironment

Dec. 14(Thu.), 201714:25-15:45

100635 3-G-W39-12-P

Poster Presentation

Madoka Terashima Kyoto University, Kyoto, Japan

Establishment of a pluripotent cell model of Nakajo-Nishimura syndrome

Dec. 14(Thu.), 2017

Odd Number / 16:00-17:00, Exhibition Systemic autoimmune
disease (3)Even Number / 17:00-18:00 Hall100636 3-E-W35-7-O/P

Presentation: 7min,
Discussion: 3min

Koji Tokoyoda

Deutsches Rheuma-Forschungszentrum Berlin(DRFZ), Berlin, Germany<em>Salmonella</em> remotely suppresses long-lasting humoral immunity

Dec. 14(Thu.), 201714:25-15:45

100637 3-H-W40-26-P

Poster Presentation

Hidemitsu Tsutsui

National Center for Global Health and Medicine
Research Institute, Tokyo, JapanThe basophil-specific protease mMCP-8 provokes an inflammatory response in the skin with Dec. 14
microvascular hyperpermeability and leukocyte infiltration(Thu.), 2017

100638 3-H-W41-14-O/P

Presentation: 7min,
Discussion: 3min

Naoto Sasaki

Department of Medical Pharmaceutics, Kobe
Pharmaceutical University, Kobe, Japan

Ultraviolet B exposure prevents atherosclerotic cardiovascular disease by regulating
immunoinflammatory responses

Dec. 14(Thu.), 201714:25-15:45

Room H

100639 3-F-W37-11-O/P

Presentation: 7min,
Discussion: 2min

Kamachi Fumitaka Faculty of Science and Technology, Tokyo

Effects of gut microbial metabolites of linoleic acid on cytokine profuction by immune cells

Dec. 14(Thu.), 201714:25-15:45

Room F

100640 2-B-W20-17-P

Poster Presentation

Ryota Sakai

Department of Microbiology and Immunology,
School of Medicine, Keio University, Tokyo,
Japan

Migration Th17 and CCL22/17-CCR4 axis are crucial in the crescentic glomerulonephritis
model

Dec. 13
16:00-17:00(Wed.), 2017

Exhibition Systemic autoimmune
disease (1)Hall100641 1-B-W3-4-O/P

Presentation: 7min,
Discussion: 2min

Michihiro
Takahama

Institute of Advanced Medical Sciences,
Tokushima University, Tokushima, Japan

RAB2B-GARIL5 complex promotes innate immune response against DNA virus

Dec. 12(Tue.), 201713:20-14:40

Room B

100642 1-B-W4-10-P

Poster Presentation

Yoshihito Suda

Department of Food, Agricultural andEnvironmental Sciences, Miyagi University,
Miyagi, Japan

Expression of complement components, C3 in lung and liver of aging mouse

Dec. 12(Tue.), 2017

Odd Number / 16:30-17:30, Exhibition Endogenous innate immunity Osamu
and inflammation-2
Even Number / 17:30-18:30 Hall
Takeuchi100643 1-I-W17-13-O/P

Presentation: 7min,
Discussion: 3min

Fumiko HONDAOZAKI

Center for Stem Cell Biology and Regenerative
Medicine Institute of Medical Science Universityof Tokyo

Evaluation of the Utility of Induced Pluripotent Stem Cells as a platform for modeling Wiskott Dec. 12
Aldrich Syndrome(Tue.), 2017100644 2-B-W20-13-P

Poster Presentation

MUNENAGASHUICHIDepartment of Periodontal Medicine, Division ofApplied Life Science, Institute of Biomedical&amp; Health Sciences, Hiroshima University,
Hiroshima, Japan

Involvement of C5a in the progression of experimental arthritis in SKG mice induced by<em>Porphyromonas gingivalis </em>infection

Dec. 13
16:00-17:00(Wed.), 2017

Exhibition Systemic autoimmune
disease (1)Hall100645 2-G-W23-19-P

Poster Presentation

Noufa Alonazi

Prince Sultan Military Medical City, Riyadh,
Saudi Arabia

The Relationship Between Vitamin D deficiency and the severity of symptoms of Food
Allergy in Children

Dec. 13
16:00-17:00(Wed.), 2017

Exhibition Allergy-3 : Allergic dermatitis,
food allergy and allergic
Kenji IzuharaHallconjunctivitis

Tomohiro
YoshimotoPresentation: 10min,
Discussion: 3min

Department of Immuno-Gene Therapy, Mie

100646 2-C-W21-12-O/P

Yoshihiro Miyahara University Graduate School of Medicine, Mie,A novel CAR-T therapy targeting MAGE-A4<sub>p230-239</sub>/HLA-A*02:01 complex
for solid tumors

Dec. 13
14:25-15:45(Wed.), 2017

Room C

Hiroaki Ikeda

Koji Tamada

100647 3-H-W40-3-P

Poster Presentation

Matsuba Shintaro

Atsuhito Nakao

YosukeKurashima100648 3-D-W32-5-P

Poster Presentation

Kiyoshi Yoshimura National Cancer Center, Tokyo, Japan

100649 3-H-W41-12-P

Poster Presentation

Takeru Ihara

Theiler&rsquo;s virus fails to stimulate plasmacytoid dendritic cell

Institute for Frontier Life and Medical

Kyoto, Japan

Center for iPS Cell Research and Application,

Department of Applied Biological Science,
University of Science, Chiba, JapanJapan

Room D

Room E

Tissue-specific immune
diseases II

Room I

Hiroto Tsuboi

Koji Yasutomo Keishi Fujio

Naganari
OhkuraTakashi Sekiya

Toshihiko
Torigoe

Yoshihiro
Hayakawa

KimitoKawahata

ShingoNakayamada

Masaki Hikida

Wataru Ise

Atsuhito Nakao

YosukeKurashima

Tissue-specific immune
diseases III

Keishi Fujio

MotomuHashimoto

Mucosal-Skin Immunity-3

Eiji Umemoto

Jun Kunisawa

Hitoshi
Kohsaka

Shinsuke
YasudaTumor immunology-2(Immunosuppression andmodulation in tumor
immunity)

Germinal center reaction andplasma cells

Odd Number / 16:00-17:00, Exhibition
Granulocyte & Mast cells
Even Number / 17:00-18:00 Hall

13:20-14:40

NaozumiIshimaru

HiroyukiOshiumiEndogenous innate immunity
and inflammation-1

Human Immunology

Cell therapy

Tatsuya Saitoh Takuya Uehata
SachikoTakamura(Akashi)Koji Yasutomo Keishi Fujio
Hitoshi
Kohsaka

Shinsuke
YasudaDec. 14(Thu.), 2017

Odd Number / 16:00-17:00, Exhibition
Granulocyte & Mast cells
Even Number / 17:00-18:00 Hall

Identification and analysis about molecules which are highly expressed in pancreatic cancer
stem-like cells

Dec. 14(Thu.), 2017

Odd Number / 16:00-17:00, Exhibition Tumor immunology-1 (Tumor Yutaka
antigens, antigen presenting
Even Number / 17:00-18:00 Hall
Kawakami
cells, anti-tumor T cells)

Hirokazu
Matsushita

The role of signal-transducing adaptor protein-1 in Concanavalin A-induced hepatitis

Dec. 14(Thu.), 2017

Odd Number / 16:00-17:00, Exhibition Tissue-specific immune
diseases III
Even Number / 17:00-18:00 Hall

MotomuHashimotoDepartment of Immunology, School of Medicine, SLPI negatively regulates LPS-induced eosinophil activation via inhibition of Elk-1
Kanazawa Medical University, Uchinada, Japan phosphorylation

Department of Immunology, Faculty of
Pharmaceutical Sciences, Hokkaido University

Room C

Takashi Fujita

29 / 30

Keishi Fujio

The 46th Annual Meeting of The Japanese Society for Immunology
Submission ID

Program No.

Oral Presentation Time

1st Author

Submission ID orderAffiliation

Title

Date

Time

Venue

Session Title

Exhibition Allergy-3 : Allergic dermatitis,
food allergy and allergicHallconjunctivitis

Chair1Chair2

Kenji Izuhara

Tomohiro
Yoshimoto

100650 2-G-W23-13-P

Poster Presentation

Eri SHIMURA

Juntendo University, School of Medicine

Influence of IL-21 signaling on skin dendritic cells

Dec. 13
16:00-17:00(Wed.), 2017

100651 3-F-W37-10-P

Poster Presentation

Lisa Fujimura

Biomedical Research Center, Chiba University,
Chiba, Japan

Roles of enteric neurons in gut mucosal immunity.

Dec. 14(Thu.), 2017

Odd Number / 16:00-17:00, Exhibition
Mucosal-Skin Immunity-3
Even Number / 17:00-18:00 Hall

Eiji Umemoto

Jun Kunisawa

100652 3-I-W42-15-P

Poster Presentation

Hiroaki Machiyama University, Tokyo, JapanTCR signaling introduces endocytic machineries at the microclusters

Dec. 14(Thu.), 2017

Odd Number / 16:00-17:00, Exhibition
T cell-2 : T cell signaling
Even Number / 17:00-18:00 Hall

SatoshiMatsudaTadashiYokosuka100653 3-B-W28-6-P

Poster Presentation

Kato Taiki

Kitasato University School of
Medicine,Sagamihara,Japan

Tetramer-based analyses of antigen-specific T cells in relapse model of experimental
autoimmune uveoretinitis in mice

Dec. 14(Thu.), 2017

Odd Number / 16:00-17:00, Exhibition Innate Lymphocyte-1 (NKT,
MAIT, gdT, NK)
Even Number / 17:00-18:00 Hall

Kensuke
ShibataKazuyaIWABUCHI

100654 1-E-W9-9-P

Poster Presentation

Arisa Morikawa

Department of Molecular and Cellular Health
Innate immune cells sense Staphylocuccus aureus-derived cysteine protease via their cell
Science, Graduate School of Pharmaceutical
Sciences, Nagoya City University, Nagoya, Japan surface molecule(s) to produce proinflammatory cytokines.

Dec. 12(Tue.), 2017

Odd Number / 16:30-17:30, Exhibition Immune response to bacteial
Goro Matsuzaki Yuki Kinjo
infections
Even Number / 17:30-18:30 Hall100655 1-D-W7-14-P

Poster Presentation

Toru Okamoto

Research Institute for Microbial Diseases, Osaka<strong>Selective TLR ligands stimulate <em>in vivo</em> pathogenicity of JEV</strong>
University

Dec. 12(Tue.), 2017

Odd Number / 16:30-17:30, Exhibition
Virus infection-1
Even Number / 17:30-18:30 Hall100656 1-E-W9-16-P

Poster Presentation

Ryosuke Uchiyama Microbiology, Nishinomiya, Japan

100657 3-I-W42-17-P

Poster Presentation

100658 2-F-W22-17-P

Deparment of Immunology, Tokyo Medical

Taro Kawai

Mitsutoshi
Yoneyama

Hyogo College of Medicine, Department of

Inflammasome and Fas-mediated IL-1&beta; contributes to Th17/Th1 cell induction inpathogenic bacterial infection

Dec. 12(Tue.), 2017

Odd Number / 16:30-17:30, Exhibition Immune response to bacteial
Goro Matsuzaki Yuki Kinjo
infections
Even Number / 17:30-18:30 Hall

Hiroki Yatsu

Division of Molecular Pathology, ResearchInstitute for Biomedical Science, Tokyo
University of Science, Noda, Japan

Regulation Mechanism of Differentiation in Type 1 Helper T cell (T<sub>H</sub>1) andFollicular Helper T cell (T<sub>FH</sub>) Specific for Influenza A Virus

Dec. 14(Thu.), 2017

Odd Number / 16:00-17:00, Exhibition
T cell-2 : T cell signaling
Even Number / 17:00-18:00 Hall

Poster Presentation

Yasuo Ouchi

Department of Mucosal Immunology, School of
Medicine, Chiba University, Chiba, Japan<strong>Generation of tumor antigen-specific CD8<sup>+</sup> T-cells with enhanced
anti-tumor activity via highly efficient CRISPR/Cas9 genome editing</strong>

Dec. 13
16:00-17:00(Wed.), 2017

100659 1-B-W4-16-P

Poster Presentation

Hiroshi Nihira

Department of Pediatrics, Faculty of Medicine,
Kyoto University, Kyoto, Japan

Deficiency of adenosine deaminase 2 (DADA2) in Japan: Clinical and genetic diversity inJapanese patients.

Dec. 12(Tue.), 2017

Odd Number / 16:30-17:30, Exhibition Endogenous innate immunity Osamu
and inflammation-2
Even Number / 17:30-18:30 Hall
Takeuchi

SachikoTakamura(Akashi)100660 3-F-W36-5-O/P

Presentation: 7min,
Discussion: 3min

Takashi Tanaka

Laboratory for Inflammatory Regulation, REKEN<strong>Microbiota-dependent development of non-alcoholic steatohepatitis (NASH) in
Center for Integrative Medical Sciences,
PDLIM2-deficient mice</strong>.
Yokohama, Japan

Dec. 14(Thu.), 201712:50-14:10

Koji Hase

Gyohei Egawa

100661 2-B-W20-19-P

Poster Presentation

Mari Kamiya

Department of Rheumatology, Graduate Schoolof Medical and Dental Sciences, Tokyo Medical
and Dental University (TMDU), Tokyo, Japan

Study of <em>in vitro</em> T cell/myotube interaction disclosed invasive and cytotoxic
nature of CD8<sup>+</sup> cells enclosed in the muscle cells.

Dec. 13
16:00-17:00(Wed.), 2017

Exhibition Systemic autoimmune
disease (1)Hall

Hitoshi
Kohsaka

Shinsuke
Yasuda100662 1-I-W17-23-O/P

Presentation: 7min,
Discussion: 3min

Kayoko Sato

Department of Cardiology, Tokyo Women's
Medical University, Tokyo, Japan

Dipeptidyl peptidase 4 (DPP-4) signaling in T cells contributes atherosclerotic development
and podocyte dysfunction

Dec. 12(Tue.), 201713:20-14:40

Room I

Human Immunology

Koji Yasutomo Keishi Fujio

100663 1-H-W16-7-O/P

Presentation: 6min,
Discussion: 2min

Natsuo Yamamoto Department of Infection Control

Anti-inflammatory effects on liver cells with flavonoids during rapid phgase in a severe sepsis

Dec. 12(Tue.), 201714:55-16:15

Room H

Cytokines and chemokines-2

Takayuki
YoshimotoTakashi
Kobayashi

100664 2-G-W23-14-O/P

Presentation: 10min,
Discussion: 3min

Yoshinori
Yamanishi

Department of Immune Regulation, Graduate
School of Medical and Dental Sciences, Tokyo
Medical and Dental University (TMDU), Tokyo,
Japan

Basophil tryptase mMCP-11 plays a crucial role in IgE-mediated, delayed-onset allergic
inflammation

Dec. 13
14:25-15:45(Wed.), 2017

Room G

Allergy-3 : Allergic dermatitis,
food allergy and allergic
conjunctivitis

Kenji Izuhara

Tomohiro
Yoshimoto100665 3-H-W40-27-O/P

Presentation: 7min,
Discussion: 3min

Kensuke Miyake

Department of Immune Regulation, Graduate
School of Medical and Dental Sciences, Tokyo
Medical and Dental University (TMDU), Tokyo,
Japan

Basophils exert antigen presentation via trogocytosis-mediated acquisition of peptide-MHC
class II complexes from dendritic cells (DCs)Dec. 14(Thu.), 201712:50-14:10

Room H

Granulocyte & Mast cells

Atsuhito Nakao

YosukeKurashima

100666 1-C-W6-8-P

Poster Presentation

Kaieda Shinjiro

Kurume university shcool of medicine

Involvement of CD163-positive Macrophages in the Pathogenesis of Arthritis via Modulationof Inflammatory Cytokine Expression in the Synovium of a Murine Model

Dec. 12(Tue.), 2017

Odd Number / 16:30-17:30, Exhibition Tissue-specific immune
diseases II
Even Number / 17:30-18:30 Hall

NaozumiIshimaru

Hiroto Tsuboi

100667 1-A-W2-18-P

Poster Presentation

YOSHIKAWA
Soichiro

Department of Immune Regulation, Tokyo
Medical and Dental University, Tokyo, Japan<strong>Prolonged Ca<sup>2+</sup> influx via STIM2 is essential for cytokine-induced IL4 production in basophil</strong>

Dec. 12(Tue.), 2017

Odd Number / 16:30-17:30, Exhibition Allergy-2: Upper airway
allergic inflammation andEven Number / 17:30-18:30 Hall
allergic responses

Tomohiro
YoshimotoRyoji Yagi

100668 1-I-W17-2-P

Poster Presentation

Saeko Shimodera

Department of Pediatrics, Kyoto University
Graduate School of Medicine, Kyoto, Japan

A first case of hemophagocytic lymphohistiocytosis type 3 (FHL3) caused by a large<em>UNC13D</em> gene duplication

Dec. 12(Tue.), 2017

Odd Number / 16:30-17:30, Exhibition
Human Immunology
Even Number / 17:30-18:30 Hall

Koji Yasutomo Keishi Fujio

100669 1-F-W11-10-P

Poster Presentation

Takuma ISSHIKI

Department of Immunology, Juntendo University
Anti-TIM-3 treatment exacerbates pulmonary inflammation and fibrosis in mice
School of Medicine, Tokyo, Japan

Dec. 12(Tue.), 2017

Odd Number / 16:30-17:30, Exhibition Combination cancer
Hiroyoshi
immunothrapy -beyond
Even Number / 17:30-18:30 Hall
immune checkpoint inhibitors- Nishikawa

30 / 30

Exhibition T cell-1: T cell development
and repertoire selection
Hall

Room F

Mucosal-Skin Immunity-2

SatoshiMatsudaTadashiYokosuka

TaishinAkiyamaTakeshi Nitta

Yoshihiro
Hayakawa