The 46th Annual Meeting of The Japanese Society for Immunology

Session Title

W1

W2

W3

Allergy-1 : Lower airway
allergic inflammation

Allergy-2: Upper airway
allergic inflammation andallergic responses

Endogenous innate
immunity andinflammation-1

Date

Dec. 12(Tue.), 2017

Dec. 12(Tue.), 2017

Dec. 12(Tue.), 2017Time

Odd Number /16:30-17:30
Even Number /17:30-18:30

Odd Number /16:30-17:30
Even Number /17:30-18:30

Odd Number /16:30-17:30
Even Number /17:30-18:30

Submission ID

Program for Poster

Program No.

1st Author

Affiliation

Abstract Title

100298 1-A-W1-1-O/P

Sho SHIBATA

Monocyte-derived macrophages in the lung contribute to the development of pulmonary emphysema
Department of Immune Regulation, Tokyo Medical and Dental University, Tokyo, Japanthrough MMP-12 production in a mouse model of COPD

100301 1-A-W1-2-P

Minoru Takeuchi

Dept. of Animal Medical Science, Kyoto Sangyo University, Kyoto, Japan<strong>Effect of H</strong><strong>ot Water Extract from Agaricus Blazei Murill on
Lipopolysaccharide (LPS) -induced Lung Inflammation and the Immunological Mechanism</strong>

100041 1-A-W1-3-O/P

Satoko Tahara-Hanaoka

Department of Immunology, Faculty of Medicine, University of Tsukuba, Tsukuba,
Japan

Inhibition of house dust mite-induced Th2 responses by Allergin-1 immunoreceptor on dendritic cells

100100 1-A-W1-4-O/P

Koji Hayashizaki

Department of Immunology, Graduate School of Medicine, Chiba University, Chiba,
Japan

Myosin light chains 9 and 12 are functional ligands for CD69 that regulate airway inflammation

100235 1-A-W1-5-P

Ryuichi Nagashima

Division of Cancer Biology and Therapeutics, Miyagi Cancer Certer Reserch Institute,
Natori, Japan<strong>Nrf2 activation suppressed lung allergic inflammation induced by type2-innate lymphoidcells.</strong>

100441 1-A-W1-6-P

Jung Yeon Hong

Department of Pediatrics and Institute of Allergy, Brain Korea 21 PLUS Project for
Medical Science, Yonsei University College of Medicine, Seoul, Korea<strong>Chitotriosidase Regulation of Allergen-induced Airway Inflammation Airways
Hyperresponsiveness and Foxp3<sup>+</sup> Treg Cells</strong>

100450 1-A-W1-7-P

Mi Na Kim

Department of Pediatrics and Institute of Allergy, Brain Korea 21 PLUS Project for
Medical science, Yonsei University College of Medicine, Seoul, Republic of Korea

ALCAM on dendritic cell contributes Th2 response in allergic airway inflammation

100321 1-A-W1-8-P

Tomohiro Tamachi

Department of Allergy and Clinical Immunology, Graduate School of Medicine, Chiba
University, Chiba, Japan

A20 (<em>Tnfaip3</em>) expressed in T cells suppresses Th2 cell-mediated allergic airway
inflammation in mice

100189 1-A-W1-9-O/P

Aiko Saku

Department of Allergy and Clinical Immunology, Graduate School of Medicine, Chiba
University, Chiba, Japan

Lung epithelial fucosylation promotes the development of house dust mite (HDM)-induced allergic
airway inflammation.

100268 1-A-W1-10-O/P

Tomomitsu Miyasaka

Division of Pathophysiology, Department of Pharmaceutical Sciences, Faculty of
Pharmaceutical Sciences, Tohoku Medical and Pharmaceutical University, Sendai,Japan

Possible involvement of CD103<sup>+</sup> dendritic cells in female-predominant Th2 priming inasthma100356 1-A-W1-11-O/P

Kentaro Fujiwara

Dept. of Immunology<strong>M1 macrophages mediate attenuation of bronchial asthma by matrix-metalloproteinase2</strong>

100473 1-A-W1-12-P

Asako TanoueDepartment of Pulmonary Medicine, Graduate School of Medical and Dental Sciences,
The role of group III secreted phospholipase A2 in allergic asthma
Kagoshima University, Kagoshima, Japan

100031 1-A-W1-13-P

Chika Kanamori

Department of Animal medical science, Faculty of Life science, Kyoto Sangyo
University, Kyoto, Japan<strong>Effects of Cryptomeria Japonica pollen and cigarette smoke on immune cells</strong>

100199 1-A-W1-14-O/P

Katsuhide Okunishi

Institute for Molecular and Cellular Regulation, Gunma University, Maebashi, Japan

Rab27 effector exophilin5 regulates IL-33 signaling in allergic immune responses

100590 1-A-W1-15-P

Masashi Ikutani

Department of Immune Regulation, Research Institute, National Center for Global
Health and Medicine, Chiba, Japan

Chronic IL-33-induced inflammation results in pulmonary arterial hypertrophy

100218 1-A-W1-16-P

Prince Baffour Tonto

Dept. of Immunology<strong>Role of eosinophils and metalloproteinase-2 in airway remodeling</strong>

100291 1-A-W1-17-O/P

Kazuyuki Nakagome

Department of Respiratory Medicine and Allergy Center, Saitama Medical University,
Saitama, Japan

Elevated periostin concentrations in the bronchoalveolar lavage fluid of eosinophilic pneumonia

100339 1-A-W1-18-P

Shigeki Katoh

Department of Respiratory Medicine, Kawasaki Medical School, Okayama, Japan

Possible role of IL-25 in eosinophilic lung inflammation in patients with eosinophilic pneumonia

100056 1-A-W2-1-P

Oji Nakamura

Department of Applied Biological Chemistry, Tokyo University of Agriculture andTechnology, Tokyo, Japan

Effect of honeybush extracts on the murine model of pollen allergy

100064 1-A-W2-2-P

Inoue Akiko

Department of Otorhinolaryngology, Toho University School of Medicine, Tokyo, Japan Study of relationship of allergy and chronic rhinosinusitis

100153 1-A-W2-3-P

Dong-Young Kim

Department of Otorhinolaryngology-Head and Neck Surgery, Seoul National University Anti-allergic effect of intranasal vitamin D treatment by inhibiting dendritic cell activation in the allergic
College of Medicine, Seoul, Korea
rhinitis mouse model

100249 1-A-W2-4-P

Ayumi Fukuoka

Department of Immunology, Hyogo College of Medicine, Nishinomiya, Hyogo, Japan

Cystatin SN inhibits Japanese cedar pollen-induced allergic rhinitis in mice.

100288 1-A-W2-5-P

Makoto Matsui

Department of Fundamental Biosciences, Shiga University of Medical Science, Otsu,
Japan

Role of neutrophils in the nasal mucosa in a mouse model of allergic rhinitis

100292 1-A-W2-6-P

Daisuke Nagakubo

Department of Fundamental Biosciences, Shiga University of Medical Science, Otsu,
Japan

Involvement of CCL28 in the pathogenesis of allergic rhinitis in a mouse model

100300 1-A-W2-7-O/P

Masaya Matsuda

Laboratory of Immunopharmacology, Faculty of Pharmaceutical Sciences, Setsunan
University, Osaka, Japan

Effects of subcutaneous immunotherapy (SCIT) on regulatory T cells in pollinosis patients

100484 1-A-W2-8-O/P

Kazuya Takeda

Laboratory of Immune regulation, Immunology Frontier Research center, Osaka
University, Suita, Japan

Ectopic T-B interaction for antigen-specific IgE antibody responses in nasal polyps of Eosinophilicchronic rhinosinusitis patients

100110 1-A-W2-9-O/P

Dat Nguyen-Tien

Division of Molecular Biology, Research Institute for Biomedical Sciences, Tokyo
University of Science<strong>A selection technique for human IgE<sup>+</sup> memory B cells and the function of the&ldquo;new&rdquo; isoform of human IgE</strong>

100113 1-A-W2-10-O/P

Mariana Almeida

Department of Immunology, Faculty of Medicine, University of Tsukuba, Tsukuba,
Japan

Inhibition of house dust mite-induced MAP kinase activation in dendritic cells by Allergin-1
immunoreceptor

100203 1-A-W2-11-P

Hirotomo Shibaguchi

Department of Biochemistry, Faculty of Medicine, Fukuoka University, Fukuoka, Japan Gene analysis of HL-60 cells and neutrophils to generate ideal chemotactic cells for HiSAT

100205 1-A-W2-12-O/P

Shihono Kato

Laboratory for Innate Immune Systems, RIKEN, IMS, Kanagawa, Japan

Role of ILC2 in the formation of maternal allergic inflammation and allergic susceptibility of the offspring

100232 1-A-W2-13-O/P

Mio Ohashi

Department of Immunoregulation, Institute of Medical Science, Tokyo Medical
University, Tokyo, Japan

Prediction of Chemical Respiratory and Contact Sensitizers by OX40L Expressionin Dendritic Cells
Using a Novel 3D Co-Culture System

100311 1-A-W2-14-O/P

Kano Tanabe

Department of Medical Technology, Kumamoto Health Science University, Kumamoto,
CaMKII regulates IgE class switch recombination via TRAF3 ubiquitination
Japan

100317 1-A-W2-15-P

Akira Awaya

Strategy for advance of melanocyte immunology from research on pollen-induced diseases(PID) such
Dermatology&amp;Epidemiology Research Institute(DERI),Totsuka,Yokohama, Japan as Kawasaki disease(KD) - Epidemiological study of KD(13): Statistical analyses reveal epidemics ofInfluenza suppress or postpone KD onsets. Coadministration

100519 1-A-W2-16-O/P

Ayako Takamori

Atopy (Allergy) Research Center, Juntendo University School of Medicine, Tokyo,
Japan<strong>Ceramide-CD300f interaction inhibits Mrgprb2-mediated mast cell activation and pseudoallergic drug reactions in mice</strong>

100553 1-A-W2-17-P

Narumi Suzuki

Laboratory for Cytokine Regulation,Research Center for Integrative Medical Science,RIKEN Yokohama Institute,Yokohama,japan

E4BP4/NFIL-3 is a critical transcription factor to control TH2 attraction into inflammation site during
chronic allergic responses.

100667 1-A-W2-18-P

YOSHIKAWA Soichiro

Department of Immune Regulation, Tokyo Medical and Dental University, Tokyo, Japan<strong>Prolonged Ca<sup>2+</sup> influx via STIM2 is essential for cytokine-induced IL-4 production
in basophil</strong>

100614 1-B-W3-1-O/P

Ryota Sato

Division of Innate Immunity, The Institute of Medical Science, The University of Tokyo,
Japan<strong>Requirement of glycosylation machinery in Toll-like receptor responses revealed by
CRISPR/Cas9 screening </strong>

100070 1-B-W3-2-O/P

Sachiko Akashi-Takamura

Aichi Medical University School of Medicine, Nagakute, Japan

C4b binding protein negatively regulates cell-surface TLRs response

100216 1-B-W3-3-O/P

Ken Takashima

Department of Immunology, Graduate School of Medicine, Hokkaido University,
Sapporo, Japan

Novel Negative Regulators for MDA5-Mediated Innate Immune Response

100641 1-B-W3-4-O/P

Michihiro Takahama

Institute of Advanced Medical Sciences, Tokushima University, Tokushima, Japan

RAB2B-GARIL5 complex promotes innate immune response against DNA virus

100188 1-B-W3-5-O/P

Naoya Sakaguchi

Research Institute for Microbial Diseases (RIMD), Osaka University, Osaka, Japan<strong>Role of GABARAP subfamily in the regulation of non-canonical inflammasome
activation</strong>

100322 1-B-W3-6-O/P

Kohsuke Tsuchiya

Cancer Research Institute, Kanazawa University, Kanazawa, Japan

Caspase-1 serves as an apoptosis-initiating caspase in the absence of Gasdermin D (GSDMD)

100181 1-B-W3-7-O/P

Ho Minh Van

Department of Emergency and Critical Care Medicine, Graduate School of Biomedical <strong>Detection of ATP-dependent inflammatory suppression of the innate immune response in
and Health Sciences, Hiroshima University
septic patients</strong>

100078 1-B-W3-8-O/P

Masahiro Nagata

Department of Molecular Immunology, Research Institute for Microbial Diseases,
Osaka University, Osaka, Japan

Intracellular metabolite, &beta;-glucosylceramide, is an endogenous adjuvant acting through Mincle

100632 1-B-W3-9-P

Yuki Nakajima

Department of Immunology, Graduate School of Medicine, The University of Tokyo

Identificdation of immunogenic endogenous RNA and its inhibitor

100629 1-B-W3-10-P

Asuka Inoue

Research and Development, Sanofi K.K., Tokyo, Japan

Immune regulation by inhibitory oligonucleotide ISM ODN for HMGB1 in inflammatory disease models

100522 1-B-W3-11-P

Motoya Murase

Graduate School of Biological Sciences, Nara Institute of Science and Technology(NAIST), Nara, Japan

Intravesicular acidification regulates lipopolysaccharide inflammation and tolerance through Toll-likereceptor 4 trafficking

100379 1-B-W3-12-P

Rina Sugimoto

Department of Cell Biological Science, Graduate School of Life Science, Hokkaido
University, Sapporo, Japan

Evaluation system for receptor expression and function in the intestinal stem cell niche

100533 1-B-W3-13-P

Hideki Sanjo

Department of Molecular and Cellular Immunology, Shinshu University Schhol of
Medicine, Nagano, Japan

Loss of TAK1 leads to TLR-driven macrophage cell death and inflammation that occur by a TNFindependent mechanism

100095 1-B-W3-14-P

Shimpei Watanabe

R&amp;D Innovation Group, Kracie Holdings, Ltd., Tokyo, Japan

Arctigenin suppresses the activation of NLRP3 and AIM2 inflammasomes.

100382 1-B-W3-15-P

Takumi Adachi

Department of Immunology, Hyogo College of Medicine, Nishinomiya, Hyogo, Japan

Purification and characterization of a unique DAMP of a potent inducer of IL-33 expression in nonhematopoietic cells

1 / 13

The 46th Annual Meeting of The Japanese Society for Immunology

Session Title

W4

W5

W6

W7

Endogenous innate
immunity andinflammation-2

Tissue-specific immune
diseases I

Tissue-specific immune
diseases II

Virus infection-1

Date

Dec. 12(Tue.), 2017

Dec. 12(Tue.), 2017

Dec. 12(Tue.), 2017

Dec. 12(Tue.), 2017Time

Odd Number /16:30-17:30
Even Number /17:30-18:30

Odd Number /16:30-17:30
Even Number /17:30-18:30

Dec. 12 (Tue.),2017

Odd Number /16:30-17:30
Even Number /17:30-18:30

Submission ID

Program for Poster

Program No.

1st Author

Affiliation

Abstract Title

100040 1-B-W4-1-O/P

Ayako Wakabayashi

Department of Microbiology and Immunology, Nippon Medical School, Tokyo, Japan

Enhancement of epithelial cell death, cytoplasmic HMGB1 expression in IECs, and increase of HMGB1
release by oral CT-stimulation

100529 1-B-W4-2-O/P

Eri Kumaki

Department of Pediatrics and Developmental biology, Tokyo Medical and Dental
University Graduate School of Medical and Dental Sciences, Tokyo, Japan

Abberant Neutrophil Function in <em>PSTPIP1</em> mutations

100325 1-B-W4-3-O/P

Akiko Ishitani

Nara Medical University, Kashihara, Nara, Japan<em>The three faces of F: HLA-F as a ligand for KIRs, a cofactor in antigen presentation, and a
receptor on B cells and monocytes, combined in an immunoregulatory capacity centered on the
inflammatory response.</em>

100353 1-B-W4-4-O/P

Toshiaki Totoki

Dept. of Immunology<strong>Overexpression of protein S exacerbates carbon tetrachloride-induced liver injury andfibrosis</strong>

100493 1-B-W4-5-O/P

Maehara Akie

Atopy (Allergy) Research Center, Juntendo University Graduate School of Medicine,Tokyo, Japan

Identification and characterization of a novel mutation of NLRP1 in a patient with a rare disease
involving severe liver fibrosis

100619 1-B-W4-6-O/P

Kiyoharu Fukushima

Department of Host Defense, Research Institute for Microbial Diseases (RIMD), Osaka
Screening of causative genes for fibrosis development in mice.
University, Osaka, Japan.

100474 1-B-W4-7-O/P

Yukari Saito

Department of Immune Regulation, Research Center for Hepatitis and Immunology,
Research Institute, National Center for Global Health and Medicine, Chiba, Japan

Activation of NK/group1-innate lymphoid cells in adipose tissues depends on the composition of fatty
acids in high fat diet.

100270 1-B-W4-8-O/P

Kafi N. Ealey

Laboratory for Innate Immune Systems, RIKEN IMS, Yokohama, Japan

Mechanisms for the regulation of adipose tissue expansion and remodeling by group 2 innate lymphoidcells

100002 1-B-W4-9-O/P

Toshihiko Kobayashi

Department of Molecular Immunology &amp; Inflammation, Research Institute, NCGM

Regulatory role of an oligopeptide transporter SLC15A3 during the systemic inflammation

100642 1-B-W4-10-P

Yoshihito Suda

Department of Food, Agricultural and Environmental Sciences, Miyagi University,
Miyagi, Japan

Expression of complement components, C3 in lung and liver of aging mouse

100202 1-B-W4-11-P

HAI T PHUNG

Department of Microbiology and Immunology, Tohoku University Graduate School of
Medicine, Sendai, JapanTNF receptor-associated factors 5 expressed in non-hematopoietic cells augments acute colonicdamage induced by dextran sulfate sodium

100316 1-B-W4-12-P

Kyohei Nishino

Department of Medicine, Shiga University of Medical Science

Analysis of the role of autophay in dextran sodium sulfate (DSS) induced experimental colitis

100212 1-B-W4-13-P

Masaaki Toda

Dept of Immunology<strong>Epigenetic mechanisms mediate the antiatherosclerotic activity of low consumption of
alcohol</strong>

100077 1-B-W4-14-P

Takashi Mino

Institute for Frontier Life and Medical Sciences, Kyoto University<strong>Regnase-1 regulates inflammatory mRNAs during pioneer rounds of translation</strong>

100355 1-B-W4-15-P

Yasuharu Watanabe

Department of Immunobiology and Pharmacological Genetics, Graduate School of
Medicine and Pharmaceutical Science for Research, University of Toyama, Toyama,Japan<strong>The interaction of neutrophils with adipocytes plays a key role in the infiltration of macrophage
into the adipose tissue</strong>

100659 1-B-W4-16-P

Hiroshi Nihira

Department of Pediatrics, Faculty of Medicine, Kyoto University, Kyoto, Japan

Deficiency of adenosine deaminase 2 (DADA2) in Japan: Clinical and genetic diversity in Japanesepatients.

100588 1-C-W5-1-O/P

Ben Raveney

Department of Immunology, National Institute of Neuroscience, NCNP, Kodaira, Tokyo, Eomes-positive cytotoxic T helper cells: a new pathogenic immune cell subset in secondaryJapan
progressive multiple sclerosis?

100535 1-C-W5-2-O/P

Chenyang ZHANG

Department of Immunology, National Institute of Neuroscience, National Center of
Neurology and Psychiatry, Kodaira, Tokyo, Japan.

<strong>Antigen-presenting cells promote Eomes expression in helper T cells through ectopic
expression of prolactin under chronic neuroinflammation</strong>

100405 1-C-W5-3-O/P

Youwei Lin

Department of Immunology, National Institute of Neuroscience, National Center of
Neurology and Psychiatry

Inverse vaccination by superior dominant peptide inhibit the reactivity to disease-associated antigens
and promote tissue-repair capacity in stabilized antigen-specific regulatory T cells to control ofrelapsing and progression of animal model of multiple

100158 1-C-W5-4-O/P

Fumitaka Sato

Kindai University, Osakasayama, Japan

Protective and detrimental effects of curdlan, a Th17 cell inducer, in immune-mediated demyelinationinduced by a neurotropic viral infection

100342 1-C-W5-5-O/P

Fumihiro Yanagimura

Department of Neurology, Brain Research Institute, Niigata University, Niigata, Japan

Differential dynamics of mucosal-associated invariant T cells in the blood and the CNS lesions ofpatients with neuromyelitis optica

100506 1-C-W5-6-O/P

Daisuke Kamimura

Psychoimmunology, Institute for Genetic Medicine, Graduate School of Medicine,
Hokkaido University, Sapporo, Japan<strong>Light-Gateway Reflex; Photopic light suppresses retinal inflammation via down-regulation of aregional adrenergic pathway</strong>

100129 1-C-W5-7-O/P

Satoshi Yamada

Department of Intelligent Mechanical Engineering, Okayama University of Science,
Okayama, Japan

Computer model of a gateway of immune cells across blood-brain barrier

100528 1-C-W5-8-O/P

Yasunobu Arima

Division of Psychoimmunology, Institute for Genetic Medicine and Graduate School of
Medicine, Hokkaido University, Sapporo, Japan

Stress-Gateway Reflex, which establishes brain micro-inflammation at specific vessels, creates a newneural pathway, which induces the dysregulation of organ homeostasis100014 1-C-W5-9-P

Yusei Miyazaki

Hokkaido Medical Center, Sapporo, Japan<strong>Fingolimod induces BAFF and expands circulating transitional B cells without activating
memory B cells and plasma cells in multiple sclerosis</strong>

100054 1-C-W5-10-P

Koji Shinoda

Department of Neurology, Neurological Institute, Graduate School of Medical Sciences, A distinct repertoire of the &gamma;&delta; T cell population is associated with disease severity of
Kyushu University, Fukuoka, Japan
multiple sclerosis100524 1-C-W5-11-P

Natsumi Nakayama

Laboratory of Biochemistry, Azabu University

The role of gangliosides in CNS autoimmune diseases

100602 1-C-W5-12-P

AKIBA Yasushi

Department of Molecular Immunology, Toho University School of Medicine, Tokyo,
Japan

Nuclear protein SATB1 is required for development of experimental autoimmune encephalomyelitis

100138 1-C-W6-1-O/P

Ota Mitsutoshi

Division of Psychoimmunology, Institute for Genetic Medicine, Hokkaido University,
Sapporo, Japan<strong>NF-kB Arthritis Inducer 1 (NAI1) in chondrocytes regulates joint inflammation via NF-kB
activation</strong>

100618 1-C-W6-2-O/P

Ikuma Nakagawa

Division of Psychoimmunology, Institute for Genetic Medicine, Hokkaido University,
Hokkaido, Japan<strong>Primary Sj&ouml;gren&rsquo;s syndrome-associated gene<em> STF1</em> regulates
inflammation via </strong><strong>NF-</strong><strong>k</strong><strong>B pathway</strong>

100099 1-C-W6-3-P

Masato Kinoshita

Department of Nephrology and Rheumatology, Gunma University Graduate School of
Medicine, Gunma, Japan

Dendritic cell-specific ablation of the protein tyrosine phosphatase Shp-1 induces autoimmune
sialadenitis characterized by infiltration of CD4<sup>+</sup> T cells and B cells

100037 1-C-W6-4-O/P

Kojiro Sato

Department of Rheumatology and Applied Immunology, Saitama Medical University,
Saitama, Japan

Analysis of the function of Nfatc1 isoforms in the differentiation of osteoclasts and an attempt to makeshort-form specific Nfatc1 knockout mice with the CRISPR/Cas9 system

100630 1-C-W6-5-O/P

Michio Yasunami

Saga-Ken Medical Centre Koseikan, Saga, Japan

Principal contribution of <em>HLA-DQ</em> alleles, <em>DQB1*06:04</em> and<em>DQB1*03:01</em>, to disease resistance against primary biliary cholangitis in a Japanese
population

100172 1-C-W6-6-O/P

Tomomi Sato

Department of Fundamental Biosciences, Shiga University of Medical Science, Shiga,Japan

Characterization of rheumatoid arthritis-associated interstitial pneumonia using collagen-induced
arthritis mice

100384 1-C-W6-7-O/P

Kunihiro Otsuka

Department of Oral Molecular Pathology, Institute of Biomedical Science, Tokushima
University Graduate School, Tokushima, Japan

Analysis of follicular helper T cells in a mouse model for Sj&ouml;gren&rsquo;s syndrome

100666 1-C-W6-8-P

Kaieda Shinjiro

Kurume university shcool of medicine

Involvement of CD163-positive Macrophages in the Pathogenesis of Arthritis via Modulation of
Inflammatory Cytokine Expression in the Synovium of a Murine Model

100545 1-C-W6-9-O/P

Namiko Okabe

Department of Rheumatology and Clinical Immunology, Graduate School of Medicine,
Kyoto University, Kyoto, Japan

Myelin basic protein promotes experimental arthritis via non-T cells.

100231 1-C-W6-10-P

Hayakawa Kunihiro

Institute for Environmental and Gender Specific Medicine, Juntendo University
Graduate School of Medicine, Chiba, Japan

Possible mechanisms of anti-arthritic effect induced by dietary &omega;-3 polyunsaturated fatty acids

100576 1-C-W6-11-O/P

Soo-hyun Chung

Center for Animal Disease Models, Research Institute for Biomedical Sciences, Tokyo
University of Science, Noda, Japan

Truncated glycan and C-type lectin ; a new therapeutic target for autoimmune arthriti

100479 1-D-W7-1-O/P

Satoshi Fukuyama

Division of Virology, Department of Microbiology and Immunology, Institute of Medical
Science, University of Tokyo, Tokyo, Japan

Effect of aging on the host response to avian influenza A(H7N9) virus infection in non-human primates

100431 1-D-W7-2-O/P

Hiroshi Ueki

Division of Virology, Department of Microbiology and Immunology, Institute of Medical
Science, University of Tokyo

Visualization of immune responses to influenza virus in mouse lung by using two-photon microscopy

100242 1-D-W7-3-O/P

Natsuko Imakita

Department of Immunology, Nara Medical University, Nara, JapanThe contribution of histone methyltransferase Setdb2 in the pathogenesis of influenza associatedencephalopathy

100116 1-D-W7-4-O/P

Kayoko Sato

Influenza Virus Research Center, National Institute of Infectious Diseases, Tokyo,
Japan

TLR agonists enhance avidity and ADCC activities of virus-specific antibodies upon a booster
immunization of influenza vaccines

100102 1-D-W7-5-O/P

Tatsuya Yamazaki

Department of Microbiology and Immunology, Aichi Medical University, School of
Medicine<strong>Neutralizing anti-hemagglutinin IgG and IgA mAb induced by gene-base hydrodynamic
injection have a therapeutic effect in<u> upper respiratory influenza virus infection</u></strong>

100246 1-D-W7-6-O/P

Masaaki Okamoto

Department of Immunology, Graduate School of Medical Sciences, Kumamoto
University, Kumamoto, Japan<strong>Circulating miR-451a in extracellular vesicles regulate innate immune cells response to
influenza A virus vaccine</strong>

100587 1-D-W7-7-O/P

Takeharu Minamitani

Laboratory of Infectious Diseases and Immunity, National Institutes of Biomedical
Innovation, Health, and Nutrition, Ibaraki, Osaka, JapanT cell and NK cell-mediated immune surveillance interferes with Epstein-Barr virus LMP-induced
lymphomagenesis in germinal center B cells

100266 1-D-W7-8-O/P

Haruna Okude

Laboratory of Molecular Immunobiology, Nara Institute of Science and Technology,
Nara, Japan

Induction of cell death by imiquimod (R837) and its role in immune responses

100066 1-D-W7-9-O/P

Tomoko Takahashi

Department of Biological Sciences, Graduate School of Science, The University ofTokyo

LGP2 upregulates apoptosis-related genes by acting as an RNA silencing modulator during viral
infection

100226 1-D-W7-10-O/P

Akihiko Komuro

Niigata University of Pharmacy and Applied Life Sciences, Niigata, Japan

A possible role of TAR-RNA binding protein phosphorylation in MDA5/LGP2-mediated cellularresponses by Cardiovirus infection

100013 1-D-W7-11-P

Motomi Yamazaki

Department of Gastroenterology, Nihon University School of Medicine

Effects of H1N1 influenza virus infection on maternal and fetal in pregnant mouse

100265 1-D-W7-12-P

Keiko Nagata

Division of Molecular Pathology, Department of Pathology, Faculty of Medicine, Tottori ImmunoglobulinG4 production is induced by reactivation of Epstein-Barr virus persistent in B
University, Yonago, Japanlymphocytes from Graves&rsquo; disease patients and controls

100357 1-D-W7-13-P

Yoshiko Murakata

Tsukuba Primate Research Center, National Institute of Biomedical Innovation, Ibaraki, <strong>Studies of incomplete control of Epstein-Barr virus infection by using cynomolgus macaquesJapanmodel.</strong>

100655 1-D-W7-14-P

Toru Okamoto

Research Institute for Microbial Diseases, Osaka University

2 / 13<strong>Selective TLR ligands stimulate <em>in vivo</em> pathogenicity of JEV</strong>The 46th Annual Meeting of The Japanese Society for Immunology

Session Title

W8

W9

Virus infection-2

Immune response tobacteial infections

Immune response toW10 mycobacteial and fungal
infections

W11

Combination cancer
immunothrapy -beyond
immune checkpoint
inhibitors-

Date

Dec. 12(Tue.), 2017

Dec. 12(Tue.), 2017

Dec. 12(Tue.), 2017

Dec. 12(Tue.), 2017Time

Odd Number /16:30-17:30
Even Number /17:30-18:30

Odd Number /16:30-17:30
Even Number /17:30-18:30

Odd Number /16:30-17:30
Even Number /17:30-18:30

Odd Number /16:30-17:30
Even Number /17:30-18:30

Submission ID

Program for Poster

Program No.

1st Author

Affiliation

Abstract Title

100053 1-D-W8-1-O/P

Takayuki Chikata

Center for AIDS Research, Kumamoto University, Kumamoto, Japan

Control of HIV-1 by an HLA-B*52:01-HLA-C*12:02 protective haplotype

100313 1-D-W8-2-O/P

Hayato Murakoshi

Center for AIDS Research, Kumamoto University, Kumamoto, Japan

Impact of a single escape mutation selected by HLA-A*24:02-restricted CD8<sup>+</sup> T cells on
HIV-1 control by HLA-B*35:01-restricted ones and T cell adaptation

100346 1-D-W8-3-O/P

Chengcheng Zou

Center for AIDS research, Kumamoto University, Kumamoto, Japan<strong>Conserved epitope-specific CTLs controlling HIV-1 replication</strong>

100177 1-D-W8-4-O/P

Takamasa Ueno

Center for AIDS Research, Kumamoto University, Kumamoto, Japan<strong>Relative resistance of MHC-B to Nef-mediated downregulation is conserved among primate
lentiviruses and correlates with reduced viral loads in HIV-1-infected individuals</strong>

100024 1-D-W8-5-O/P

Eiji SHINYA

Nippon Medical School, Tokyo, Japan

Hematopoietic cell kinase (Hck) augmented the interaction between HIV-1 Nef and SERINC5, whichmight promote HIV-1 infection by excluding SERINC5 from virion incorporation in immature dendritic
cells

100210 1-D-W8-6-O/P

Nami Iwamoto

Immuno Technology Section, Vaccine Research Center, NIAID, NIH

Development of Chimeric Antigen Receptor (CAR)-Transduced CD8 T cells Using SIV-specific
Neutralizing Anibodies

100600 1-D-W8-7-O/P

Daichi Yamasoba

Laboratory of Infection and Prevention, Institute for Frontier Life and Medical Sciences,
Identification of a novel HIV-1 restriction factor which selectively degrades viral transcripts.
Kyoto University, Kyoto, Japan

100263 1-D-W8-8-O/P

Takuya Sueyoshi

Laboratory of Molecular Immunobiology, Graduate School of Biological Sciences, Nara RNA-binding protein Hu antigen R (HuR) plays an important role in antiviral innate immune responses
Institute of Science and Technology (NAIST), Nara, Japan
via mRNA stabilization

100170 1-D-W8-9-O/P

Takahisa Kouwaki

Department of Immunology, Graduate school of Medical Sciences, Faculty of Life
Sciences, Kumamoto University, Kumamoto, Japan<strong>Zyxin</strong> <strong>is a positive factor in a MAVS/IPS-1-dependent</strong><strong>type</strong> <strong>?</strong> <strong>interferon</strong> <strong>expression
pathway during viral infection.</strong>

100227 1-D-W8-10-P

Yoshihiro Kumagai

Department of Microbiology and Immunology, Nippon Medical School, Tokyo, Japan<strong>THE ANALYSIS OF THE INTERACTION BETWEEN HIV-1 GP 120 AND </strong><strong>bCHEMOKINE RECEPTOR BY USING MULITIVALENT V3 EPITOPES GRAFTED AT
IMMUNOGLOBULIN HYPERVARIABLE REGIONS </strong>

100261 1-D-W8-11-P

Tomotaka Okamura

Tsukuba Primate Research Center, National Institutes of Biomedical Innovation, Health Non-pathogenic AIDS virus carrying an adjuvant molecule induced strong cellular immunity and longand Nutrition, Ibaraki Japanterm protective efficacy against pathogenic SHIV.

100454 1-D-W8-12-P

Warunthorn Monwan

Laboratry of Molecular Immunobiology, Graduate School of Biological Sciences, Nara
Institute of Science and Technology, Nara, Japan

Characterization of Nucleoporin (Nup) genes that mediate antimicrobial innate immune responses

100628 1-D-W8-13-P

Kazuya TAKEDA

Faculty of Medicine, Tohoku Medical and Pharmaceutical University, Sendai, Miyagi,
Japan

Theiler&rsquo;s virus fails to stimulate plasmacytoid dendritic cell100372 1-E-W9-1-O/P

Takayuki Matsumura

Department of Immunology, National Institute of Infectious Diseases, Tokyo, Japan<strong>Balance of pro- and anti-inflammatory cytokines in immature myeloid cells involved in outcomeof severe invasive group A <em>Streptococcus</em> infections</strong>

100080 1-E-W9-2-O/P

Imai Takashi

Division of Molecular Immunology, Medical Institute of Bioregulation, Kyushu University, <strong>Glycolipids in group A <em>Streptococcus </em>are recognized by Mincle to trigger host
Fukuoka, Japanimmune responses</strong>

100136 1-E-W9-3-P

Yukiko Akahori

International University of Health and Welfare, Narita, Japan

Dectin-1 mediates innate immune responses in <em>Streptococcus pneumoniae</em> infection

100383 1-E-W9-4-O/P

Rin Yokoyama

Medical Microbiology, Mycology and Immunology, Tohoku University Graduate Schoolof Medicine, Miyagi, Japan<strong>Dectin-2-mediated signaling triggered by serotype 3 <em>Streptococcus pneumoniae</em>and its contribution to host immune response</strong>

100491 1-E-W9-5-O/P

Shogo Takatsuka

Dept. Chemother. Mycoses, Nat. Inst. Infect. Dis.

Follicular helper NKT cells augment germinal center B cell formation by a protein-based pneumococcal
vaccine100490 1-E-W9-6-O/P

Seitaro Nakagawa

Department of Dermatology, Chiba University<em>Staphylococcus aureus </em>virulent PSM&alpha; peptides induce keratinocyte IL-1 and IL-36
release to orchestrate IL-17-dependent skin inflammation

100108 1-E-W9-7-P

Krisana Asano

Department of Microbiology and Immunology, Hirosaki University Graduate School of
Medicine, Aomori, Japan<strong>Establishment of a mouse uterine infection model of <em>Staphylococcus aureus </em>forstudying a role of toxic shock syndrome toxin-1</strong>

100359 1-E-W9-8-P

Matsui KatsuhikoDepartment of Microbial Science and Host Defense, Meiji Pharmaceutical University,
Tokyo, Japan<strong>Mast cells stimulated with peptidoglycan from <em>Staphylococcus aureus</em> enhance thedevelopment of Th1 cells</strong>

100654 1-E-W9-9-P

Arisa Morikawa

Department of Molecular and Cellular Health Science, Graduate School of
Pharmaceutical Sciences, Nagoya City University, Nagoya, Japan

Innate immune cells sense Staphylocuccus aureus-derived cysteine protease via their cell surface
molecule(s) to produce proinflammatory cytokines.

100422 1-E-W9-10-P

Hiromi Miyazaki

Division of Traumatology, Research Institute, National Defense Medical College,
Tokorozawa, Japan

Coenzyme Q10 supplementation protects against methicillin-resistant Staphylococcus aureus infection
in burn-injured mice

100340 1-E-W9-11-O/P

Nobuhiro Nakamoto

Keio University School of Medicine, Tokyo, Japan<strong>Integrated collaboration of intestinal microbiota induces bacterial translocation and Th17
immune response in primary sclerosing cholangitis</strong>

100137 1-E-W9-12-P

Shiho Suzuki

Dept Bacterial Infection and Host Responce, Tokyo Medical and Dental Univ (TMDU),Tokyo, JapanThe microbial-host interactions that drive the activation of the Nlrc4 inflammasome in<em>Shigella</em>-infected macrophages

100319 1-E-W9-13-P

Yoshihiko Sugitani

Department of Medicine, Shiga University of Medical Science, Otsu, JapanThe therapeutic effects of elemental diet and intestnal microbiota

100079 1-E-W9-14-P

Hideo Negishi

Department of Molecular Immunology, Institute of Industrial Science, The University ofTokyo, Tokyo, Japan

Identification and analysis of commensal bacteriophage in the intestine

100517 1-E-W9-15-O/P

Ayako Kaitani

Atopy (Allergy) Research Center, Juntendo University School of Medicine, Tokyo,
Japan

CD300f suppresses neutrophil recruitment to LPS-injected skin: A role of CD300f in gram-negative
bacterial skin infections

100656 1-E-W9-16-P

Ryosuke Uchiyama

Hyogo College of Medicine, Department of Microbiology, Nishinomiya, Japan

Inflammasome and Fas-mediated IL-1&beta; contributes to Th17/Th1 cell induction in pathogenic
bacterial infection

100046 1-E-W9-17-P

Kazuhiro Negoro

Department of Immunology, Institute of Advanced Medicine, Wakayama Medical
University, Wakayama, Japan

An Ets family member, Ets2 is required for Cholera toxin-induced arginase-1 gene expression

100093 1-E-W9-18-P

Masanori Iseki

Department of Immunology and Molecular Genetics, Kawasaki Medical School,
Kurashiki, Japan

BST-1/CD157 on B cells negatively regulates Toll-like receptor signaling

100603 1-E-W10-1-O/P

Ei'ichi Iizasa

Department of Immunology, Field of Infection and Immunity, Graduate School of
Medical and Dental Sciences, Kagoshima University, Kagoshima

Two ITAM-coupled receptors recognizing Mycobacterial mycolic acid-containing lipids and having thedifferent roles.

100577 1-E-W10-2-P

Masayuki Umemura

Tropical Biosphere Research Center, University of the Ryukyus, Okinawa, Japan

Involvement of IL-17A-producing TCR &gamma;&delta;<sup>+</sup> T cells in late protective
immunity against pulmonary <em>Mycobacterium tuberculosis </em>infection

100274 1-E-W10-3-O/P

Naoto Nouchi

IL-21 signaling drives differentiation of short-lived effector CD8<sup>+</sup>T cells from early effector
Division of Host Defense, Medical Institute of Bioregulation, Kushu University, Fukuoka,
cells but does not inhibit exhaustion following <em>Mycobacterium bovis</em> Bacillus CalmetteJapan
Gu&eacute;rin infection in mice

100160 1-E-W10-4-O/P

Shihoko Komine-Aizawa

Nihon University School of Medicine, Tokyo, Japan

100283 1-E-W10-5-O/P

Yusuke Tsujimura

Tsukuba Primate Research Center, National Institutes of Biomedical Innovation, Health
The immune responses induced by BCG vaccination in the non-human primate TB modeland Nutrition, Ibaraki, Japan

100250 1-E-W10-6-P

Masahiro Kitabatake

Department of Immunology, Nara Medical University, Nara, Japan<strong>CD8<sup>+</sup> T cells play a critical role for the murine model of immune reconstitution
inflammatory syndrome.</strong>

100144 1-E-W10-7-O/P

Yasunobu Miyake

Division of Molecular and Cellular Immunoscience, Department of Biomolecular
Sciences, Faculty of Medicine, Saga University, Saga, Japan

Immunosuppressive receptor, Siglec binds to pathogenic fungus, <em>Trichophyton
mentagrophytes</em>, and negatively regulates host immune responses

100304 1-E-W10-8-O/P

Daiki Tanno

Department of Medical Microbiology, Mycology and Immunology, Tohoku University
Graduate School of Medicine

Dectin-2-mediated signaling triggered by the cell wall structures of <em>Cryptococcus
neoformans</em>

100378 1-E-W10-9-P

Yuki KITAI

Medical Microbiology, Mycology and immunology, Tohoku University Graduate Schoolof Medicine<strong>Involvement of Dectin-2 in the recognition and phagocytosis of</strong><em><strong>Cryptococcus neoformans </strong></em><strong>by dendritic cells</strong>

100329 1-E-W10-10-P

Kotone Kawamura

Department of Medical Microbiology, Mycology and Immunology, Tohoku University
Graduate School of Medicine, Miyagi, japan

Activation of Dectin-2-mediated signaling by cryptococcal capsular polysaccharides: Comparison
between <em>Cryptococcus neoformans</em> and <em>C. gattii</em>

100579 1-E-W10-11-P

Yuki SATO

Medical Microbiology, Mycology and Immunology, Tohoku University Graduate Schoolof Medicine, Miyagi, Japan

Effect of Mincle-deficiency on the host immune response against <em>Cryptococcus neoformans</em>
infection

100458 1-E-W10-12-O/P Keigo Ueno

Department of Chemotherapy and Mycoses, National Institute of Infectious Diseases,
Tokyo, Japan

Dendritic cell-based vaccination induces lung resident memory Th17 cells that ameliorate pulmonary
infection with highly virulent <em>Cryptococcus gattii</em>100121 1-E-W10-13-P

Sonoko Tasaki

Section of Infection Biology, Department of Functional Biosciences, Fukuoka Dental
College.

Investigation of mechanisms underlying the T cell response in oral candidasis.

100345 1-F-W11-1-P

Matsuoka Shuji

Department of Patology and Oncology Juntendo University School of Medicine

Anapocosis: Direct cell death of lymphoma cells induced by mAbs.

100228 1-F-W11-2-P

Ouji-Sageshima Noriko

Department of Immunology, Nara Medical University, Kashihara, JapanThe critical role of HLA class Ib proteins, HLA-E and HLA-F, expressed on tumor cells

100044 1-F-W11-3-O/P

Naoto Nishii

Department of Molecular Immunology, Graduate School, Tokyo Medical and Dental
University

Systemic administration of low dose TLR7 agonist augments antitumor responses in the PD-1
checkpoint blockade-resistant and regulatory T cell-dominant murine tumor models

100565 1-F-W11-4-O/P

Shime Hiroaki

Department of Immunology,?Nagoya City University Graduate School of Medical
Sciences, Nagoya, Japan

Toll-like receptor 2 ligand and interferon-&gamma; suppress anti-tumor T cell responses by enhancing
the immunosuppressive activity of monocytic myeloid-derived suppressor cells

100182 1-F-W11-5-P

Etsuko Harada

Department of Immunology, Mie University School of Medicine, Mie, Japan<strong><em>Agaricus blazei</em></strong><strong> Murrill extract inhibits</strong><strong> theexpression of immune checkpoint molecules in a lung cancer cell line</strong>

100373 1-F-W11-6-P

Shota Kajiyama

Kobayashi Pharmaceutical Co., Ltd., Osaka, Japan

Investigation of the effect of a combination of immune checkpoint inhibitor and Lentinula Edodes
Mycelia (L.E.M.) extract on antitumor response in CT26 colon carcinoma-bearing mice.

100375 1-F-W11-7-O/P

Nobuo Tsukamoto

Division of cellular Signaling, Institute for Advanced Medical Research, Keio University Berberine augments tumor antigen specific T cells <em>in vivo</em> through metabolic remodeling in
School of Medicine, Tokyo, Japan
CD8<sup>+</sup> T cells in tumors and lymph nodes

100371 1-F-W11-8-O/P

Alok Kumar

Department of Immunology and Genomic Medicine, Graduate School of Medicine,
Kyoto University, Kyoto, Japan

100617 1-F-W11-9-O/P

kagawa Masaki

Division of Cellular Signaling Institute, for Advanced Medical Research, Keio University Immunomodulation of ovarian clear cell carcinoma by targeting HNF-1&beta;-NF-kB-IL6 pathway
School of Medicine
enhances anti-tumor immunity

100669 1-F-W11-10-P

Takuma ISSHIKI

Department of Immunology, Juntendo University School of Medicine, Tokyo, Japan

Anti-TIM-3 treatment exacerbates pulmonary inflammation and fibrosis in mice

100409 1-F-W11-11-O/P

Chang-Yu Chen

Department of Molecular Preventive Medicine, Graduate School of Medicine, The
University of Tokyo, Tokyo, Japan<strong>Low-dose HMGN1 synergistically enhances anti-tumor immunity in CD4 depleting antibodytreated mice</strong>

100393 1-F-W11-12-O/P

Nanumi Han

Division of Immunobiology, Institute for Genetic Medicine, Hokkaido University,
Sapporo, Japan<strong>Identification of factors that affect myeloid cells in immunotherapeutic-resistanttumors</strong>

3 / 13

Induction of CD8<sup>+</sup>- MHC-I-restricted, antigen-specific T cells by recombinant BCG
protects against mycobacterial infection<strong>Indicators of mitochondrial activation in T cells could be a biomarker to predict the PD-1
blockade therapeutic efficacy.</strong>The 46th Annual Meeting of The Japanese Society for Immunology

Session Title

W12

W13

W15

Immune responses incacer immunotherapy

Hematopoiesis andimmune environments

Cytokines andchemokines-1

Date

Dec. 12(Tue.), 2017

Dec. 12(Tue.), 2017

Dec. 12(Tue.), 2017

Time

Dec. 12 (Tue.),2017

Odd Number /16:30-17:30
Even Number /17:30-18:30

Odd Number /16:30-17:30
Even Number /17:30-18:30

Submission ID

Program for Poster

Program No.

1st Author

Affiliation

Abstract Title

100365 1-F-W12-1-O/P

Hirohito Ishigaki

Department of Pathology, Shiga University of Medical Science, Otsu, Japan,<strong>The hemoperfusion column removing LAP positive cells activates the tumor-specific immunity
in a cynomolgus monkey</strong>

100087 1-F-W12-2-O/P

Harada Michishige

RIKEN Center for Integrative Medical Science (IMS)

CD81 is associated with non-apoptotic cell death in B cell lymphoma cell lines through HLADR&alpha;/&beta; engagement

100176 1-F-W12-3-P

Makoto Kubo

Division of Immunology, Kitasato University School of Allied Health Sciences,
Kanagawa, Japan

Analysis of immune responses in prostate cancer patients received iridium-192 high-dose-rate prostatebrachytherapy

100285 1-F-W12-4-O/P

Takeshi Yamada

System Biology,Kanazawa university,Kanazawa,Japan<strong>Features of immune response induced </strong><strong>by </strong><strong>Gemcitabine in</strong><strong>pancreatic ductal adenocarcinoma</strong> <strong>model</strong>

100350 1-F-W12-5-P

Erica YADA

Department of Cancer Immunotherapy, Kanagawa Cancer Center Research Institute,
Kanagawa, Japan

Next-generation sequencing analysis of gemcitabine (GEM) resistant mechanism using patient-derived
xenograft (PDX) model in pancreatic cancer

100192 1-F-W12-6-O/P

Kikuya Sugiura

Department of Advanced Pathobiology, Graduate School of Life and Environmental
Sciences, Osaka Prefecture University, Izumisano, Japan

Manipulation of tumor microenvironment by cytokine gene transfection enhances dendritic cell-based
immunotherapy

100200 1-F-W12-7-P

Mariko Takami

Department of Medical Immunology, Graduate School of Medicine, Chiba University,
Chiba, Japan

AhR signaling enhances the moDC function to activate NKT cells

100259 1-F-W12-8-P

Kazuki Misato

Vaccine Creation Project, BIKEN Innovative Vaccine Research Alliance Laboratories,
Research Institute for Microbial Diseases, Osaka University

Development of a cancer vaccine by using dendritic cell-targeting peptide

100358 1-F-W12-9-P

Shunsuke Takese

Department of Pharmacokinetics and Biopharmaceutics, Institute of Biomedical
Sciences, Tokushima University, Tokushima, JapanThe combined effect of liposomal oxaliplatin with cancer vaccine on anticancer therapy.

100352 1-F-W12-10-O/P

Yoshino Tanaka

Division of Immunobiology, Institute for Genetic Medicine, Hokkaido University,
Sapporo, Japan

Dying but not dead cancer cells exert the effect of cell-based cancer vaccine

100335 1-F-W12-11-P

Kaori Denda-Nagai

Division of Glycobiologics, Intractable Research Center, Juntendo University Graduate Difference in humoral immune response after immunization with glycosylated MUC1 between C57BL/6
School of Medicine, Tokyo, Japanmice and MUC1 transgenic mice

100224 1-F-W12-12-O/P

Serina Tokita

Department of Pathology, Sapporo Medical University School of Medicine, Sapporo,Japan

HLA-A24 ligandome analysis identifies a neoantigen that elicits strong CTL responses

100026 1-G-W13-1-P

Ikuo Nobuhisa

Department of Stem Cell Regulation, Medical Research Institute, Tokyo Medical and
Dental University (TMDU), Tokyo, Japan

Role of adhesion molecules induced by a transcription factor Sox17 in intra-aortic hematopoietic cellcluster formation in midgestation mouse embryos

100497 1-G-W13-2-P

Eriko Sumiya

Institute for Genetic Medicine, Hokkaido University, Sapporo, Japan

Fate mapping of RANKL-expressing cells in the fetal bone100254 1-G-W13-3-P

Takahiro Noguchi

Department of Immunology and Cell Biology, Osaka University Graduate School of
Medicine, Osaka, Japan

Dynamic analysis of hematopoietic stem cells in vivo by using intravital imaging techniques

100109 1-G-W13-4-O/P

Takao Sudo

Department of Immunology and Cell Biology, Osaka University Graduate School of
Medicine, Osaka, Japan

Stressed microenvironment induced by 5-FU promotes the proliferation of HSPC in bone marrow

100324 1-G-W13-5-P

Yoshikazu Hayashi

International Research Center for Medical Sciences, Kumamoto University, Kumamoto,<strong>Impact of inflammatory stress on early hematopoiesis</strong>Japan

100496 1-G-W13-6-O/P

Yukiko Doi

Department of Hematology and Oncology, Osaka University Graduate School of
Medicine, Suita, Osaka, JapanSATB1 expression is useful to identify the lymphoid-lineage-biased trajectory of functionally fluctuatinghematopoietic stem cells.

100312 1-G-W13-7-O/P

Junichiro Takano

Laboratory for Immune Regeneration, RIKEN Center for Integrative Medical Sciences,
Yokohama, Japan<strong>Varinat PRC1.1 is required for specification of hematopoietic progenitor cells toward B
lymphoid lineage</strong>

100204 1-G-W13-8-O/P

Yohei Kawano

Department of Immune Regulation, Tokyo Medical and Dental Universiy Graduate
School, Tokyo, Japan

Establishment of a novel culture system for long-term proliferating hematopoietic progenitors withlymphoid and myeloid potential from normal mouse bone marrow without genetic manipulations

100551 1-G-W13-9-O/P

Tatsuya Shishido

Department of Immunochemistry, Research Institute for Microbital Disease, Osaka
University

Crucial role of CD74 in hematopoietic cell differentiation

100336 1-G-W13-10-O/P Masashi Kanayama

Department of Immunology, Duke University School of Medicine, Durham, North
Carolina, USA.

Balancing population sizes of myeloid and lymphoid cells by osteopontin isoforms

100229 1-G-W13-11-P

Chiba, Japan<strong>Niche-induced myeloproliferative-like disease caused by overexpression of Tlx1 i<em>n situ</em>in splenic stromal cells</strong>

100241 1-G-W13-12-O/P Akihisa Oda

Research Institute for Biomedical Sciences Tokyo Universitiy of Science, Chiba, Japan<strong>Niche-induced myeloproliferative-like disease caused by overexpression of Tlx1 i<em>n situ</em>in splenic stromal cells</strong>

100244 1-G-W13-13-P

Ueno Yuta

Laboratory of Molecular Biology and Immunology, Department of Biological Scienceand Technology, Tokyo University of Science<strong>Two mesenchymal progenitor cell populations in the spleen defined by a novel threedimensional culture system</strong>

100540 1-G-W13-14-P

Toshiki Tezuka

Division of Development and Aging, Research Institute for Biomedical Sciences, Tokyo Defects in splenic architectural organization by postnatal deletion of the gene encoding a transcription
University of Science, Chiba, Japanfactor Tlx1 in spleen mesenchymal cells

100124 1-G-W13-15-P

Krutula NairRIKEN Center for Integrative Medical Sciences, Yokohama, JapanA ThPOK-independent CD4-skewed differentiation by loss of Tet proteins and SATB1

100097 1-G-W13-16-O/P Yasuyuki Saito

Division of Molecular and Cellular Signaling, Department of Biochemistry andMolecular Biology, Kobe University Graduate School of Medicine, Kobe, Japan

SIRP&alpha;<sup>+</sup> dendritic cells regulate homeostasis of fibroblastic reticular cells via TNF
receptor ligands in the adult spleen

100367 1-G-W13-17-O/P Kazuki Sato

Department of Immunology, Faculty of Medicine, University of Tsukuba, Ibaraki, Japan Marginal reticular cells act as a non-professional phagocyte for clearance of apoptotic B cells

100302 1-G-W13-18-O/P Arata Takeuchi

Department of Immunology, Graduate School of Medical and Dental Sciences, Niigata Six different types of mesenchymal stromal cells provide the framework of multi-layered
University, Niigata, Japan
subcompartments in lymph node100498 1-G-W13-19-P

Satomi Komori

Division of Molecular and Cellular Signaling, Department of Biochemistry andMolecular Biology, Kobe University Graduate School of Medicine, Kobe, Japan<strong>Development of a novel primary culture system for lymphoid organ fibroblastic reticular
cells</strong>

100438 1-G-W13-20-P

Yasuhiro Kanda

Department of Immunology and Medical Zoology, Niigata University Graduate Schoolof Medical and Dectal sciences

Live imaging of the allogeneic T cell elimination in secondary lymphoid organs

100512 1-G-W13-21-P

Yoshihiro Ueda

Molecular Genetics, Institute of Biomedical Science, Kansai Medical University<strong>Regulation of cell polarization by Rap1 via NDR/Rab8 axis upon chemokine
stimulation</strong>

100567 1-G-W13-22-P

Toshihiro Komatsu

Department of Immunology, School of Medicine, Kochi University, Kochi, Japan

Extravasation of CTLs occurs by recognizing the MHC-peptide complexes cross-presented by vascularendothelial cells.

100568 1-G-W13-23-P

Junya Ohtake

Cancer Vaccine Center, Kanagawa Cancer Center, Yokohama, Japan<strong>Comprehensive analysis of immunological tumor environment in colorectal cancer</strong>

100347 1-H-W15-1-O/P

Kentaro Asayama

Dept of Immunology<strong>A novel mouse model of spontaneous lung cancer caused by lung TGF-&beta;1overexpression</strong>

100483 1-H-W15-2-O/P

Mayu Kaetsu

Department of Life Science and Medical Bioscience, Waseda University, Tokyo, Japan Colonic inflammation induces a transient increase in serum LECT2 level.

100411 1-H-W15-3-O/P

Wooseok Seo

RIKEN IMS Center for Integrative Medical Sciences,Yokohama, Japan

Regulation of CCL5 expression by Runx complexes and two stage-specific enhancers

100508 1-H-W15-4-O/P

Sunyi Joo

Division of Mucosal Immunology, Department of Microbiology and Immunology, The
Institute of Medical Science, The University of Tokyo, Japan<strong>Critical role of the CCR5-CCL5 cascade for the preferential migration of HSV-2-specificeffector cells to the vaginal mucosa upon intranasal immunization </strong>

100107 1-H-W15-5-O/P

Mizuho Nosaka

Department of Forensic Medicine, Wakayama Medical University, Wakayama, Japan

Absence of CCR5 axis exaggerates thrombus formation through reduced uPA, tPA and VEGF
expression in murine DVT mode

100061 1-H-W15-6-O/P

Masaaki Kawano

Department of Allergy and Immunology, Faculty of Medicine, Saitama Medical
University, Saitama, Japan<strong>Dopamine fluctuates cytokine secretion in innate and adaptive immune responses</strong>

100150 1-H-W15-7-O/P

Keiko Yoshimoto

Division of Rheumatology, Department of Internal Medicine, Keio University School of
Medicine, Tokyo, Japan

BAFF signaling inhibitors ameliorate enhanced production of IL-6 and IL-10 by pSS monocytes andconsequently suppress IgG overproduction by affecting differentiation of B cells.

100309 1-H-W15-8-O/P

Mizoguchi Izuru

Department of Immunoregulation, Institute of Medical Science, Tokyo Medical
University, Tokyo, Japan<strong>A Novel Role for Epstein-Barr Virus-Induced Gene 3 to Augment IL-23 Receptor</strong><strong>&alpha;</strong> <strong>Protein Expression through A Lectin Chaperone Calnexin</strong>

100625 1-H-W15-9-O/P

Hironao Suzuki

Division of Psychoimmunology, Institute for Genetic Medicine, Hokkaido University,
Hokkaido, Japan<strong>RNA Splicing Mediator 1 (RSM1) regulates inflammation via alternative splicing of DNA
methyltransferase Dnmt3b</strong>

100115 1-H-W15-10-P

Takehiko Shibata

Department of Immunology, National Institute of Infectious Diseases, Tokyo, JapanThe role of RSV-induced Gas6/Axl signaling in secondary bacterial infection.

100161 1-H-W15-11-P

Yuji Takeda

Department of Immunology, Yamagata University Faculty of Medicine, Yamagata,Japan

Analysis of cytokine signals using flow cytometry is useful for detection of contractive and fluctuating
signals.

100193 1-H-W15-12-P

YAMAMOTO Shinya

Division of Chemotherapy, Kindai University Faculty of Pharmacy, Osaka, Japan

A highly active form of lymphotactin/XCL1 (XCL1-CC3) functions as a potent adjuvant to accumulate
CD103+XCR1+ cross-presenting dendritic cells and induce CD8+ CTL-mediated antitumor andantiviral effects

100195 1-H-W15-13-P

KAMBARA Hirokazu

Division of Chemotherapy, Kindai University Faculty of Pharmacy, Osaka, Japan

CCL28-deficiency altered microbiota in the colon and aggravated DSS-induced colitis in mice

100197 1-H-W15-14-P

MATSUO Kazuhiko

Division of Chemotherapy, Kindai University Faculty of Pharmacy, Osaka, Japan

CCR4 is involved in atopic dermatitis-like skin lesions induced by topical sensitization of ovalbumin and&delta;-toxin using a hydrogel patch in mice

100397 1-H-W15-15-P

Hiroki Tanaka

World Premier Institute Immunology Frontier Research Center (WPI-IFReC), Osaka
University, Osaka, Japan

Regnase-1 phosphorylation induced by proinflammatory cytokines controls stability of its target
mRNAs.

100611 1-H-W15-16-P

Numasaki Muneo

Tohoku University Hospital, Sendai, Japan

IL-32 promotes the cell growth of malignant methothelioma

Akihisa Oda

4 / 13

The 46th Annual Meeting of The Japanese Society for Immunology

Session Title

W16

W17

W18

Cytokines andchemokines-2

Human Immunology

Helper T cells

DateDec. 12(Tue.), 2017

Dec. 12(Tue.), 2017

Dec. 12(Tue.), 2017Time

Odd Number /16:30-17:30
Even Number /17:30-18:30

Odd Number /16:30-17:30
Even Number /17:30-18:30

Odd Number /16:30-17:30
Even Number /17:30-18:30

Submission ID

Program for Poster

Program No.

1st Author

Affiliation

Abstract Title

100534 1-H-W16-1-O/P

Kazuo Okamoto

Department of Osteoimmunology, Graduate School of Medicine and Faculty of
Medicine, The University of Tokyo, Tokyo, Japan

100279 1-H-W16-2-O/P

Koki Hirashima

Department of immunology, Graduate School of Pharmaceutical Sciences, Hokkaido
University<strong>Tyk2 positively regulates <em>P. acnes</em>-induced acute inflammation</strong>

100007 1-H-W16-3-O/P

Takashi Izawa

Department of Orthodontics and Dentofacial Orthopedics, Tokushima University
Graduate School of Biomedical Sciences, Tokushima, Japan

Crosstalk between cytokine RANKL and AhR signaling in osteoclasts controls bone homeostasis100146 1-H-W16-4-O/P

Yurina Miyajima

Laboratory for Innate Immune Systems, RIKEN IMSFunction of BMP2 and BMP7 produced by ILC2 in the adipose tissue100308 1-H-W16-5-O/P

Ippei Koshi

Department of Molecular and Cellular Immunology, Shinshu University Graduate
School of Medicine

Branching cytokine signals for an effector function and cell survival via a discrete common &beta; chain
subregion in murine primary basophils

100318 1-H-W16-6-O/P

Yuki Hikichi

Laboratory for Innate Immune Systems, RIKEN Center for Integrative Medical Sciences Post-transcriptional regulation of type 2 cytokine gene expression in ILC2

100663 1-H-W16-7-O/P

Natsuo Yamamoto

Department of Infection Control

Anti-inflammatory effects on liver cells with flavonoids during rapid phgase in a severe sepsis

100477 1-H-W16-8-O/P

Jae-won Chang

Graduate School of Frontier Sciences, The University of Tokyo, Chiba, JapanThe first distinction and observation of single molecular dynamics between Interleukin-2 with
Intereleukin-2 receptor and Interleukin-15 with Interleukin-15 receptor through Diffracted X-ray Tracking

100104 1-H-W16-9-O/P

Kazuko Uno

Louis Pasteur Center for Medical Research

Using non-negative matrix factorization analysis of IFN/Cytokine production and those of serum levels
to identify groups at high-risk of disease or those in the early stages of disease

100016 1-H-W16-10-P

Munehiro Yamaguchi

Department of Internal Medicine, Division of Allergology and Respiratory Medicine,
School of Medicine, Showa University, Tokyo, Japan

IL-34 induces lung fibrosis via M2 macrophages differentiation in mouse lung injured model

100045 1-H-W16-11-P

Izumi Sasaki

Department of Immunology, Institute of Advanced Medicine, Wakayama Medical
University, Wakayama, Japan

Roles of arginine and methionine metabolism in cholera toxin-induced adjuvant effects

100105 1-H-W16-12-P

Toshikazu Kondo

Department of Forensic Medicine, Wakayama Medical University, Wakayama, JapanThe absence of CCL3 exaggerates CaCl<sub>2</sub>-induced aortic aneurysm

100141 1-H-W16-13-P

Yasu-Taka Azuma

Laboratory of Veterinary Pharmacology, Division of Veterinary Science, Osaka
Prefecture University Graduate School of Life and Environmental Science, Izumisano,Japan

Exacerbated TNBS-induced colitis in interleukin-19 knockout mice

100165 1-H-W16-14-P

Kyosuke Kanai

Department of Virology, Tottori University Faculty of Medicine, Yonago, Japan

Role of IL-35 in Lipopolysaccharide-Induced Airway Eosinophilia

100463 1-H-W16-15-P

Riyoko Tamai

Department of Oral Medical Science, Ohu University School of Dentistry, Fukushima,
Japan

Alendronate induces caspases-independent cell death via NLRP3 and ASC

100591 1-H-W16-16-P

Kei Matsuno

Department of Respiratory Medicine, Juntendo University School of Medicine, Tokyo,
Japan

TWEAK enhances epithelial mesenchymal transition and chemokine production in human bronchial
epithelial cells

100010 1-I-W17-1-O/P

Yuki Hitomi

Department of Human Genetics, Graduate School of Medicine, the University of Tokyo, Identification of the disease causal variants in human primary biliary cholangitis (PBC) susceptibility
Tokyo Japangene loci <em>NFKB1/MANBA</em>

100668 1-I-W17-2-P

Saeko Shimodera

Department of Pediatrics, Kyoto University Graduate School of Medicine, Kyoto, Japan

A first case of hemophagocytic lymphohistiocytosis type 3 (FHL3) caused by a large<em>UNC13D</em> gene duplication

100297 1-I-W17-3-O/P

Ryutaro IWABUCHI

Department of Life Science and Medical Bioscience, Waseda University, Tokyo, Japan

Human GM-CSF and Flt3-L induce reconstitution and maturation of human myeloid dendritic cells inhumanized mice

100412 1-I-W17-4-P

Yusuke Ohno

Department of Molecular Life Science, Tokai University School of Medicine, Isehara,Japan<strong>Pregnant humanized mouse as a model of human pregnant immunity</strong>

100440 1-I-W17-5-P

Asami Hanazawa

Central Institute for Experimental Animals, Kawasaki, Japan<strong>NOG human M-CSF transgenic mice enhance differentiation and maturation of humanmonocytes and macrophages</strong>

100445 1-I-W17-6-P

Ikumi Katano

Central Institute for Experimental Animals, Kawasaki, Japan

Human macrophages which developed into NOG-human GM-CSF/IL-3 Tg mice after hematopoietic
stem cells phagocytosed mouse erythrocytes and induced serious anemia.

100011 1-I-W17-7-P

Tomonori Hayashi

Department of Molecular Biosciences, Radiation Effects Research Foundation,
Hiroshima, Japan<strong>Relationship between T-cell Frequencies before Vaccination, Cytokine Levels, and Influenza
Vaccine Response</strong>

100111 1-I-W17-8-P

Segawa Seiji

Department of Internal Medicine, Faculty of Medicine, University of Tsukuba, Japan.

The analysis of placenta specific 8 in monocytes from Adult Still&rsquo;s disease100466 1-I-W17-9-P

Kohsuke IMAI

Department of pediatrics, Tokyo Medical and Dental University, Tokyo, Japan

Diagnostic method for primary immunodeficiency using spectral flow cytometry

100525 1-I-W17-10-P

JeongHoon Park

Department of Immunopathology, IFReC, Osaka University, Osaka, Japan<strong>Study of Human Autoimmune Diseases Enabled by Gene Editing in Reporter Cell
Lines</strong>

100526 1-I-W17-11-P

Yuka Kobayashi

Laboratory of Immunology, Institute for Frontier Life and Medical Sciences, Kyoto
University, Kyoto, JapanThe construction and application of human-type artificial lymphoid tissues

100569 1-I-W17-12-P

Hirofumi Shibata

Department of Pediatrics, Kyoto University Graduate School of Medicine, Kyoto, Japan

A novel human Cytotoxic Lymphocyte-based functional assays for primary hemophagocytic
lymphohistiocytosis

100643 1-I-W17-13-O/P

Fumiko HONDA-OZAKI

Center for Stem Cell Biology and Regenerative Medicine Institute of Medical Science
University of Tokyo

Evaluation of the Utility of Induced Pluripotent Stem Cells as a platform for modeling Wiskott Aldrich
Syndrome

100180 1-I-W17-14-O/P

Daisuke SUZUKI

Center for iPS Cell Research and Application, Kyoto University, Kyoto, Japan

Differential natural killer (NK) cell immunity against class-I human leukocyte antigen (HLA)-knockout(KO) platelets and megakaryocytes

100154 1-I-W17-15-O/P

Iwamoto Sanju

Division of Physiology and Pathology, Department of Pharmacology, Toxicology andTherapeutics, Showa University of Pharmacy, Tokyo, Japan

Atypical development of human Th17 lineage from na&iuml;ve CD4 T cells in psoriasis.

100278 1-I-W17-16-O/P

Nozomi Kuse

Center for AIDS Research, Kumamoto University, Kumamoto, Japan<strong>Effective priming of functional HIV-1-specific CD8<sup>+</sup> T Cells from na&iuml;ve T
cells using STING ligand</strong>

100398 1-I-W17-17-P

Kaori Hayashi

Department of Obstetrics and Gynecology, Shiga University of Medical Science, Otsu,
Japan

Efficacy of spontaneous occurring endometriosis by extracorporeal circulation in cynomolgus monkey

100403 1-I-W17-18-O/P

Iyoda Tomonori

RIKEN Center for Integrative Medical Sciences, Yokohama, Japan

Improvement of NK cell function against multiple myeloma cells by an adjunctive effect of activatedinvariant natural killer T (NKT) cells

100532 1-I-W17-19-P

Atsushi Kadowaki

National Institute of Neuroscience, National Center of Neurology and Psychiatry, Tokyo, CCR9+ CD4+ memory T cells dependent on gut microbiota and age are altered in secondaryJapan
progressive multiple sclerosis

100548 1-I-W17-20-P

Morita Kentaro

Department of Immunology and Parasitology, School of Medicine, University ofOccupational and Environmental Health, Japan, Kitakyushu, Japan

Effect of triterpenoid anticancer drug CuD on peripheral blood lymphocytes from a patient withrecurrent ATLL

100627 1-I-W17-21-P

Shimizu Mikito

Osaka University, Osaka, Japan

Febuxostat Ameliorates Secondary Progressive Experimental Autoimmune Encephalomyelitis by
Restoring Mitochondrial Energy Production in a GOT2-dependent Manner100631 1-I-W17-22-P

Hiroyuki Yoshitomi

Institute for Frontier Life and Medical Sciences、Kyoto University, Kyoto, Japan

Transcriptional regulation of PD-1<sup>+</sup>CD4<sup>+</sup>T cells under inflammatory
conditions

100662 1-I-W17-23-O/P

Kayoko Sato

Department of Cardiology, Tokyo Women's Medical University, Tokyo, Japan

Dipeptidyl peptidase 4 (DPP-4) signaling in T cells contributes atherosclerotic development andpodocyte dysfunction

100042 1-I-W18-1-O/P

Soh Yamazaki

Department of Biochemistry, Toho University School of Medicine

The AP-1 transcription factor JunB is essential for development of Th17 cells

100082 1-I-W18-2-O/P

SHINYA TANAKA

Research Institute for Biomedical Sciences, Tokyo University of Science, Chiba, Japan<strong>Tripartite motif-containing 33 (Trim33) mediates a pro-inflammatory phenotype of Th17
cells.</strong>

100620 1-I-W18-3-O/P

Keiko Yasuda

Laboratory of Experimental Immunology, Institute for Frontier Life and Medical
Sciences, Kyoto University, Kyoto, Japan

Satb1 controls the differentiation and terminal effector function of Th17 cells

100207 1-I-W18-4-O/P

Yuko Okuyama

Department of Microbiology and Immunology, Tohoku University Graduate School of
Medicine, Miyagi, JapanA new regulator of OX40 co-signaling controls autoimmune neuroinflammation mediated by
CD4<sup>+</sup> T cells

100135 1-I-W18-5-P

Kyoko NISHIDA

Department of Immunology and Pathology, National Center for Global Health andMedicine

NQO1 play a pathogenic role in autoimmune diseases through the suppression of IL-10 production in
Th17 cells

100173 1-I-W18-6-P

Nobumasa Watanabe

Tokyo Metropolitan Institute of Medical Science, Tokyo, Japan

MHC-II-dependent autonomous immune responses of in vitro-differentiated Th17 cells

100009 1-I-W18-7-O/P

Kota Kokubo

Department of Immunology, Graduate School of Medicine, Chiba University, Chiba,Japan<strong>Menin controls the memory Th2 cell function by maintaining the epigenetic integrity of Th2
cells.</strong>

100320 1-I-W18-8-O/P

Makoto Kuwahara

Department of Immunology, Graduate School of Medicine, Ehime University, Ehime,Japan

The transcriptional repressor Bach2 regulates differentiation of pathogenic Th2 cells

100543 1-I-W18-9-O/P

Harada Yasuyo

Research Institute for Biomedical Science, Tokyo University of Science, Chiba, Japan<strong>Role of follicular helper T cells and TH2 cells in IgE mediated </strong><strong>active
cutaneous anaphylaxis</strong>

100413 1-I-W18-10-O/P

Masaki Tajima

Laboratory of Host Defenses, NIAID, NIH, Maryland, USA<strong>IL-10-Producing Tr2 cells Induced by mTOR/CEBP&beta; Signaling Regulate Hyphal <em>C.
albicans</em> Kidney Infection</strong>

100444 1-I-W18-11-P

Tomo Takebe

Pharmaceutical Sciences, Tokyo University of Science, Chiba, Japan

A novel mouse model for tracking the fate of follicular helper T cells

100513 1-I-W18-12-P

Kazuki Sakamoto

Pharmaceutical Sciences, Tokyo University of Science, Chiba, Japan

Dysregulation of humoral immunity in Foxp3 conditional knockout mice

100376 1-I-W18-13-P

Shojiro Ikezaki

Section of Infection Biology, Department of Functional Bioscience, Fukuoka Dental
Collage.

A novel alternative splicing of T-cell signaling molecule modulates TCR-mediated responses in Th2
cells

100547 1-I-W18-14-P

Yuriko Tanaka

Department of Molecular Immunology, Toho University School of Medicine, Tokyo,
Japan

The presence of T cells with both Th1 and Th2 characteristics in mice

100333 1-I-W18-15-P

Akiho Oniyama

Medical Microbiology, Mycology and Immunology, Tohoku University Graduate Schoolof Medicine, Miyagi, Japan

Immunological analysis of the mechanism for higher virulence of <em>Cryptococcus gattii</em>
infection using a transgenic mouse expressing T cell antigen receptor for 98 kDa mannoprotein

100088 1-I-W18-16-P

Izumi Kurata

Division of Rheumatology, Department of Internal Medicine, Faculty of Medicine,
University of Tsukuba, Tsukuba, JapanThe Role of Follicular Helper 17 T cells and Desialylation of Autoantibody in Glucose-6-phosphate
Isomerase Induced Arthritis

100063 1-I-W18-17-P

Shunta Kaneko

Department of Internal Medicine, Faculty of Medicine, University of Tsukuba, Ibaraki,
Japan.

The RORgt-CCR6-CCL20 axis enhances Th17 cells invasion into the synovia of patients in rheumatoid
arthritis

100294 1-I-W18-18-P

Hayato Yabe

Research Institute for Frontier Medicine , Sapporo Medical University School of
Medicine , Hokkaido , Japan

Regulatory mechanisms of the production of IgG4 in IgG4-related dacryoadenitis and sialadenitis

5 / 13A distinct role of an EF-hand motif protein in the hematopoietic cell lineage

The 46th Annual Meeting of The Japanese Society for Immunology

Session Title

W19 Mucosal-Skin Immunity-1

W20

W21

Systemic autoimmune
disease (1)Cancer Cell Therapy

Date

Dec. 13(Wed.), 2017

Dec. 13(Wed.), 2017

Dec. 13(Wed.), 2017

Time

Submission ID

Program for Poster

Program No.

1st Author

Affiliation

Abstract Title

100179 2-A-W19-1-P

Jianshi Jin

RIKEN Quantitative Biology Center (QBiC), Osaka, Japan

A novel high-throughput method for bacteria counting based on <em>de-novo</em> 16S rRNA
sequence identification with single-base resolution

100118 2-A-W19-2-P

Siddhika Pareek

Laboratory of Immune Regulation, Graduate School of Medicine, Osaka University,
Osaka, Japan<strong>Comparative analysis of gut microbiome diversity between Japanese and Indian cohorts
exhibits a diet-dependent synergism between bacteria and fungi</strong>

100381 2-A-W19-3-O/P

Daisuke Takahashi

Keio University Faculty of Pharmacy, Tokyo, Japan

Microbial fermentation product butyrate Ameliorates Autoimmune Arthritis.

100162 2-A-W19-4-P

Masahisa Hemmi

Graduate School of Pharmaceutical Sciences, Osaka University,Osaka, Japan

Th17 promotes the induction of antigen-specific gut-mucosal CTLs following intramuscular vaccinationof an adenovirus vector

100499 2-A-W19-5-O/P

Kiyoshi Hirahara

Department of Immunology, Graduate School of Medicine, Chiba University

Memory-type ST2<sup>+</sup>CD4<sup>+</sup> T cells participate in the steroid-resistant pathologyof eosinophilic pneumonia

100169 2-A-W19-6-P

Ito Sayami

Project for Vaccine and Immune Regulation, Graduate School of Pharmaceutical
Sciences, Osaka University

Elucidation of the induction mechanism of transcutaneous immune responses with the self-dissolving
microneedle patch

100306 2-A-W19-7-P

Kanae Niimi

International Education and Research Center for Food and Agricultural Immunology,
Graduate School of Agricultural Science, Tohoku University, Miyagi, Japan

Development of immune and microbial environments is independently regulated in the mammary gland

100117 2-A-W19-8-O/P

Takahiro Nagatake

Laboratory of Vaccine Materials and Laboratory of Gut Environmental System, National 17,18-EpETE, a metabolite of omega-3 essential fatty acids, inhibited neutrophil mobility andInstitutes of Biomedical Innovation, Health and Nutrition (NIBIOHN), Osaka, Japanameliorated skin inflammation in DNFB-induced contact hypersensitivity model

100258 2-A-W19-9-O/P

Emi Furusawa

Department of Molecular Immunology , Tokyo Medical and Dental
University,Tokyo,Japan

Silencing of B7-DC/PD-L2 in the cutaneous dendritic cells using siRNA inhibits contact allergy

100419 2-A-W19-10-P

Daisuke TAKABAYASHI

Narashino, Chiba , Japan

Roles of MGL2 positive DC and Basophil on type 2 Contact Hypersensitivity model mice.

100090 2-A-W19-11-O/P Tomohiro FUKAYADivision of Immunology, Department of Infectious Diseases, Faculty of Medicine,
University of Miyazaki

Critical role of IL-22 binding protein in the control of skin inflammation

100282 2-A-W19-12-P

Ryuta Muromoto

Faculty of Pharmaceutical Sciences, Hokkaido University, Sapporo, Japan

Basal STAT3 activity maintained by TYK2 is required for IL-17-induced I&kappa;B-&zeta; expression in
keratinocytes

100257 2-A-W19-13-P

Airi Masaki

Department of Plastic and Reconstructive Surgery, Tohoku University school, Miyagi,
Japan

Critical role of interferon (IFN) - &gamma; in the skin wound healing

100264 2-A-W19-14-O/P Mari Tenno

Department of Immune Regulation Research Institute National Center for Global
Health and Medicine, Chiba, Japan

Disruption of Lnk increases severity of dextran sulfate sodium-induced acute colonic inflammation

100085 2-A-W19-15-P

College of Bioresource Sciences, Nihon University, Kanagawa, Japan

miR-21-5p regulates intestinal epithelial permeability through ADP-ribosylation factor 4 (ARF4)

16:00-17:00

16:00-17:00

16:00-17:00

Kazuaki Nakata

100128 2-A-W19-16-O/P Yuki Usui

Division of Systems Immunology, Institute of Medical Science, The University of Tokyo <strong>Maintenance of intestinal barrier function by long-term intake of LB81 yogurt</strong>

100067 2-A-W19-17-O/P Chiao-Ching Hsu

Laboratory of Immune Regulation, Graduate School of Medicine, Osaka University,Japan<strong>Human LYPD8 protein has motility inhibitory functions to pathogenic flagellated
bacteria</strong>

100280 2-A-W19-18-P

Atsushi Nishida

Shiga University of Medical Science, Otsu, Japan

Expression of Human Cathelicidin Peptide LL-37 in Inflammatory Bowel Disease

100034 2-B-W20-1-O/P

Sumie Hiramatsu

Department of Nephrology, Rheumatology, Endocrinology and Metabolism, Okayama
DNA Methylation-dependent regulation of Cathepsin E gene expression by the transcription factor
University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences,
Kaiso in MRL/lpr mice.
Okayama, Japan.

100012 2-B-W20-2-O/P

Takeshi Machida

Department of Immunology, Fukushima Medical University, Fukushima, Japan<strong>Significant role for splenic marginal zone B cells in anti-dsDNA autoantibody production inlupus-prone mice with an MRL background</strong>

100191 2-B-W20-3-P

Atsushi Nomura

Department of Immunology, Juntendo University School of Medicine, Tokyo, Japan

Comparative analysis of neuroinflammation in Lupus-prone mice

100131 2-B-W20-4-O/P

Takamasa Cho

Division of Clinical Nephrology and Rheumatology,Niigata University, Niigata,Japan

Anti-ribosomal-P antibody induces psychosis and hepatitis

100407 2-B-W20-5-P

Hiroyuki Nishimura

Toin Human Science and Technology Center, Toin University of Yokohama, Yokohama Epistatic interaction between <em>fcgr2b</em> and <em>Slam</em> family genes in susceptibility toJapandefective foreign protein-induced tolerance

100096 2-B-W20-6-O/P

Sonia Zeggar

Department of Nephrology,Rheumatology,Endocrinology and Metabolism,Okayama
University graduate school of medecine,Okayama,Japan

Lgals9 deficiency attenuates nephritis and arthritis in pristane induced mice model of SLE

100196 2-B-W20-7-O/P

Shin-Ichiroh Saitoh

The Institute of Medical Science, The University of Tokyo, Tokyo, Japan.

ADP-libosylation factor-like 8b is required for pathogenesis of mouse models of Systemic Lupus
Erythematosus

100430 2-B-W20-8-P

Akira Iizuka

Department of Internal Medicine, Faculty of Medicine, University of Tsukuba, Ibaraki,Japan

The regulatory role of Allergin-1 in autoantibody production

100119 2-B-W20-9-O/P

Norio Hanata

Department of Allergy and Rheumatology, Graduate School of Medicine, The
University of Tokyo, Tokyo, JapanThe effects of <em>peptidylarginine deiminase 4</em> in imiquimod-induced lupus model mice.

100348 2-B-W20-10-O/P Masahiro Nakashima

Immunology and Microbiology, National Defense Medical College, Tokorozawa, Japan

Repeated administrations of &alpha;-galactosylceramide slow the progression of lupus nephritis in
BWF1 mice

100068 2-B-W20-11-P

Division of Transplantation Immunology, National Center for Child Health andDevelopment, Tokyo, Japan<strong>Combination of 5-aminolevulinic acid and iron prevents skin fibrosis in murine
sclerodermatous grafts-versus-host disease</strong>

100544 2-B-W20-12-O/P Takuto Ohki

Division of Psychoimmunology, Institute for Genetic Medicine, Graduate School of
Medicine, Hokkaido University<strong>Symmetric-Gateway Reflex, which develops </strong><strong>symmetrical inflammation
between joints is induced by the specific sensory pathway in a rheumatoid arthritis model</strong>

100644 2-B-W20-13-P

MUNENAGA SHUICHI

Department of Periodontal Medicine, Division of Applied Life Science, Institute of
Biomedical &amp; Health Sciences, Hiroshima University, Hiroshima, Japan

Involvement of C5a in the progression of experimental arthritis in SKG mice induced by<em>Porphyromonas gingivalis </em>infection

100072 2-B-W20-14-P

Mareki Ohtsuji

Toin Human Science and Technology Center, Department of Biomedical Engineering,Toin University of Yokohama,Kanagawa,Japan<strong>Inhibitory effect of the blocking of monocyte recruitment from the blood on spontaneously
occurring arthritis </strong><strong>in arthritis-prone Fc&gamma;RIIB-deficient mice</strong>

100092 2-B-W20-15-P

Nobuhito NEMOTO

Department of immunology, Yamagata University, Yamagata, Japan

Integrated analysis of intestinal immunity at initial onset and relapse stages in arthritis mouse model

100593 2-B-W20-16-P

Chiharu Tomi

Department Immunology, National Institute of Neuroscience, NCNP, Kodaira, Tokyo,
Japan

Roles of NR4A2 for pathogenic properties of autoreactive T helper cells in lupus-prone mice.

100640 2-B-W20-17-P

Ryota Sakai

Department of Microbiology and Immunology, School of Medicine, Keio University,
Tokyo, Japan

Migration Th17 and CCL22/17-CCR4 axis are crucial in the crescentic glomerulonephritis model

100143 2-B-W20-18-P

Yuki Tanaka

Psychoimmunology, Institute for Genetic Medicine, Hokkaido University, Sapporo,Japan<strong>Enriched environment, which might suppresses the Gateway Reflex attenuated thedevelopment of EAE via inhibiting immune cell accumulation in the L5 spinal cord.</strong>

100661 2-B-W20-19-P

Mari Kamiya

Department of Rheumatology, Graduate School of Medical and Dental Sciences, Tokyo Study of <em>in vitro</em> T cell/myotube interaction disclosed invasive and cytotoxic nature of
Medical and Dental University (TMDU), Tokyo, Japan
CD8<sup>+</sup> cells enclosed in the muscle cells.

100443 2-C-W21-1-O/P

Kiyomi SHITAOKA

Department of Innovative Cancer Immunotherapy, Graduate School of Medicine andPharmaceutical Sciences, University of Toyama, Toyama City, Japan

Majority of tumor infiltrating lymphocytes in B16F10 melanoma recognized tumor-associated antigens,but not melanoma-associated antigens or neoantigens.

100142 2-C-W21-2-P

Hiroshi Hamana

Department of Innovative Cancer Immunotherapy, Graduate School of Medicine andPharmaceutical Sciences, University of Toyama, JapanT cell receptor (TCR) gene cloning from tumor infiltrating lymphocytes of breast cancer patients toward
TCR gene therapy

100209 2-C-W21-3-P

Yusuke Takahashi

Department of Immunology, Graduate School of Medicine and Pharmaceutical
Science, University of Toyama, Japan<strong>T cell receptor repertoire of PD-1<sup>+</sup>CD137<sup>+</sup> and PD1</strong><strong><sup>&minus;</sup></strong><strong>CD137</strong><strong><sup>&minus;</s
up></strong><strong> tumor infiltrating lymphocytes in various cancers</strong>

100467 2-C-W21-4-P

Eiji Kobayashi

Department of Immunology, University of Toyama, Toyama, JapanTCR repertoire analysis of antigen-specific T cells using immunospot array assay on a chip (T-ISAAC)
technology

100123 2-C-W21-5-P

Shuhei Yonamine

Department of Dermatology, Graduate School of Medicine, University of the Ryukyus,
Nishihara, Okinawa, Japan.

Rapid isolation of tumor antigen specific antibodies from semi-synthetic alpaca VHH phage display
library for cancer immunotherapy.

100328 2-C-W21-6-O/P

Satomi Okada

Department of Oncology, Nagasaki University Graduate School of Biomedical
Sciences, Nagasaki, Japan

Development of TCR gene therapy with allogeneic &ldquo;Stealth T cells&rdquo; deficient in
endogenous TCR and HLA class I molecules100327 2-C-W21-7-O/P

Ngoc M Pham

Department of Surgery, Shiga University of Medical Science, Otsu, Japan

Co-stimulation via OX40 signal <em>in vitro</em> to generate tumor antigen-specific CTLs for
adoptive cell transfer therapy

100571 2-C-W21-8-O/P

Raul Vizcardo

Surgery Branch, National Cancer Institute, National Institutes of Health, Bethesda MD,
USA

Developing the next generation of iPSC cell-based immunotherapies

100503 2-C-W21-9-O/P

Seiji Nagano

Institute for Frontier Life and Medical Sciences, Kyoto University<strong>iPSCs transduced with TCR gene give rise to potent CTLs with antigen specific cytotoxic
activity comparable to those from T-iPSCs </strong>

100029 2-C-W21-10-P

Soki Kashima

Department of immunology, Institute for Frontier Life and Medical Sciences, Kyoto
University, Kyoto, Japan

WT1-specific CTLs regenerated from T cell derived iPS cells exert therapeutic effect in xenograftmodel of renal cell carcinoma

100039 2-C-W21-11-P

Rong Zhang

Division of Cancer Immunotherapy, Exploratory Oncology Research &amp; Clinical
Trial Center, National Cancer Center, Kashiwa, Japan

Type 1 IFN-producing myeloid cells influence on host immune system to inhibit tumor growth100646 2-C-W21-12-O/P Yoshihiro Miyahara

Department of Immuno-Gene Therapy, Mie University Graduate School of Medicine,Mie, Japan

A novel CAR-T therapy targeting MAGE-A4<sub>p230-239</sub>/HLA-A*02:01 complex for solid
tumors100351 2-C-W21-13-P

Project for Vaccine and Immune Regulation, Graduate School of Pharmaceutical
Sciences, Osaka University

Immunological quality and performance of tumor vessel-targeting CAR-T cells prepared by mRNA-EP
for clinical research

Chi Liu

Kento Fujiwara

6 / 13

The 46th Annual Meeting of The Japanese Society for Immunology

Session Title

W22

W23

W24

T cell-1: T cell
development andrepertoire selection

Date

Dec. 13(Wed.), 2017

Allergy-3 : Allergic
Dec. 13dermatitis, food allergy(Wed.), 2017and allergic conjunctivitis

Immune response toparasite infections

Dec. 13(Wed.), 2017Time

16:00-17:00

Submission ID

Program for Poster

Program No.

1st Author

Affiliation

Abstract Title

100062 2-F-W22-1-O/P

Yoichi Sutoh

Iwate Tohoku Medical Megabank Organization, Iwate Medical University, Yahaba,Japan<strong>Origin of thymic selection inferred from the deviated antigen receptor usage inlamprey</strong>

100184 2-F-W22-2-O/P

Katsuto Hozumi

Tokai University School of Medicine, Isehara, Japan

Molecular machinery for the maintenance of differentiation potential toward T/B cell lineages inhematopoietic stem/progenitor cells by Lmo2

100271 2-F-W22-3-P

Shinji Fujimoto

Institute for Frontier Life and Medical Sciences, Kyoto University, Kyoto, Japan

D1V14(inverted), an oddly rearranged <em>Tcrb</em> in normal thymus

100592 2-F-W22-4-P

Honomi Saito

Department of Molecular and Cellular Immunology, Shinshu University School of
Medicine, Matsumoto, Japan

Forced over-expression of T-bet transcription factor in thymocytes inhibits DN to DP transition

100101 2-F-W22-5-O/P

Satoshi Kojo

Lab. for Transcriptional Regulation, RIKEN IMS, Yokohama, Japan

Regulation of Runx3 activity in immune system development by the C-terminal end amino acidsequence

100377 2-F-W22-6-P

Haruki Katsumata

Dept of Urology, Tokyo Women’s Medical Univ, Tokyo, Japan.

In Vitro Stimulation with &alpha;-galactosylceramide Expands
CD4<sup>+</sup>CD25<sup>+</sup>Foxp3<sup>&minus;</sup> Regulatory T Cell Precursors in
Murine Thymocytes

100091 2-F-W22-7-O/P

Kenta Kondo

Institute of Advanced Medical Sciences, University of Tokushima, Tokushima, Japan.

Thymoproteasome-dependent positive selection conditions <em>in vivo</em> immune responses inCD8<sup>+</sup> T cells

100538 2-F-W22-8-O/P

Takeshi Nitta

Department of Immunology, The University of Tokyo, Tokyo, Japan<strong>Human thymoproteasome variations influence CD8 T cell repertoire</strong>

100423 2-F-W22-9-P

Kana Misawa

Kitasato University School of Medicine, Sagamihara, Japan

Analyses of genes expressed in the cortical thymic epithelial cells in immuno-compromised,<em>alymphoplasia</em> mice

100134 2-F-W22-10-O/P

Kazumasa Kaneko

Graduate School of Engineering, The University of Tokyo, Tokyo, Japan

Mathematical modeling of thymic T cell development via interaction with thymic epithelial cells

100542 2-F-W22-11-P

Masashi Kajita

Institute of Industrial Science, The University of Tokyo, Japan

Affinity amplification for selective T cell response to specific ligands

100133 2-F-W22-12-P

Ryo Yokota

Institute of Industrial Science, the University of Tokyo, Tokyo, Japan

Quantification of inter-sample differences in repertoire of T cell receptors

100183 2-F-W22-13-P

Hiromichi Tsurui

Department of Pathology, Juntendo University School of Medicine

Precise estimation of residue-residue interaction in TCR-pMHC complex by Fragment MolecularOrbitan (FMO) calculation

100019 2-F-W22-14-O/P

Osamu Kaminuma

Center for Life Science Research, University of Yamanashi

Establishment of non-transgenic monoclonal T cell receptor-expressing mice

100447 2-F-W22-15-P

Fu Lian LYU

Department of Immunology, Graduate School of Medicine and Pharmaceutical
Sciences, University of Toyama, 2630 Sugitani, Toyama 930-0194, Japan

A novel method to produce high amounts of recombinant MHC/peptide complexes for isolation of
antigen-specific human TCRs

100596 2-F-W22-16-P

Takeyuki Shimizu

Department of Immunology, School of Medicine, Kochi University, Kochi, Japan

Construction of a TAP deficient HLA class I-binding assay system with the use of CRISPR/Cas9 system

100658 2-F-W22-17-P

Yasuo Ouchi

Department of Mucosal Immunology, School of Medicine, Chiba University, Chiba,Japan<strong>Generation of tumor antigen-specific CD8<sup>+</sup> T-cells with enhanced anti-tumor
activity via highly efficient CRISPR/Cas9 genome editing</strong>

100050 2-G-W23-1-O/P

Kazuhiko Yamamura

Department of Dermatology, Graduate School of Medical Sciences, Kyushu University,
The transcription factor EPAS1 links DOCK8 deficiency to atopic skin inflammation via IL-31 induction
Fukuoka, Japan

100058 2-G-W23-2-O/P

Akihiko Murata

Division of Immunology, Department of Molecular and Cellular Biology, School of Life
Science, Faculty of Medicine, Tottori University, Japan

Local skin memory response in contact dermatitis involves tissue resident memory T cells

100164 2-G-W23-3-O/P

Seiji Kamijo

Atopy (Allergy) Research Center, Juntendo University Graduate School of Medicine,Tokyo, Japan

Protease allergen-induced local IL-17A production in skin tissue and accumulation of IL17A<sup>+</sup> &gamma;&delta; T cells in skin draining lymph nodes; possible contribution toenhancement of skin eosinophilia and serum IgE response

100201 2-G-W23-4-P

Worawalun HIRUNWIDCHAYARAT

Department of Molecular Immunology, Graduate School, Tokyo Medical and Dental
University.

Site-specific regulation of oral mucosa-recruiting CD8<sup>+</sup> T cells -Comparison of contact
allergy between skin and oral mucosa-

100400 2-G-W23-5-O/P

Kazumasa Kanemaru

Department of Immunology, Faculty of Medicine, University of Tsukuba, Ibaraki, Japan <strong>Clec10a suppresses house dust mite-induced dermatitis</strong>

100451 2-G-W23-6-P

Ken Igawa

Department of Dermatology, Dokkyo Medical University, Mibu, Japan

Therapeutic effect of the improved version Stat6 decoy ODN containing ointment utilizing newtechnology ILTS&reg; on murine skin inflammatory responses.

100455 2-G-W23-7-P

Sekiguchi Kota

Laboratory of Microbiology and Immunology, School of Pharmaceutical Sciences,
University of Shizuoka, Shizuoka, Japan

A triacylglycerol, tributyrin, has an adjuvant effect in a mouse contact hypersensitivity model

100501 2-G-W23-8-P

Takeshi Wada

Division of Molecular Medicine, Institute for Genome Research, Tokushima University,
Tokushima, Japan

Exacerbation of oxazolone-induced atopic dermatitis in a mouse model of hyper-IgE syndrome

100554 2-G-W23-9-P

Tsukasa Ugajin

Tokyo Medical and Dental University, Tokyo, Japan<strong>Bilirubin oxidation derived from oxidative stress is associated with disease severity of atopic
dermatitis</strong>

100583 2-G-W23-10-P

Masayuki Kitajima

Depertment of Immunology and Pathology, Research Institute National Center for
Global Health and Medicine

Role of TSLPR on CD4 T cells in exacerbation of skin inflammation.

100605 2-G-W23-11-P

Michiyuki Kasai

Department of Immunology, School of Medicine, Kochi University,

Application with nano-sized cyanoacryl particles ameliorates experimental dermatitis through thebacteriocidal activity

100650 2-G-W23-12-P

Eri SHIMURA

Juntendo University, School of Medicine

Influence of IL-21 signaling on skin dendritic cells

100664 2-G-W23-13-O/P Yoshinori Yamanishi

Department of Immune Regulation, Graduate School of Medical and Dental Sciences,
Tokyo Medical and Dental University (TMDU), Tokyo, Japan

Basophil tryptase mMCP-11 plays a crucial role in IgE-mediated, delayed-onset allergic inflammation

100213 2-G-W23-14-P

College of Medicine, Dongguk University, Gyeonggi-do, South Korea

Protective effects of agonistic anti-4-1BB antibody on the development of imiquimod-induced psoriasislike dermatitis in mice

100081 2-G-W23-15-O/P MAYUMI UETA

Departments of Frontier Medical Science and Technology for Ophthalmology, Kyoto
Prefectural University of Medicine, Kyoto, Japan

Difference in the tear cytokines between chronic Stevens-Johnson syndrome patients and Atopic
keratoconjunctivitis

100073 2-G-W23-16-P

Kazunobu OKON

Department of Applied Biological Chemistry, Tokyo University of Agriculture andTechnology

Studies of the anti-allergic activity of honeybush

100394 2-G-W23-17-P

Hee Soon Shin

Korea Food Research Institute, Sungnam-si, Korea

Baicalein induces CD4+Foxp3+ T cells and enhances intestinal barrier function in a mouse model offood allergy

100645 2-G-W23-18-P

Noufa Alonazi

Prince Sultan Military Medical City, Riyadh, Saudi Arabia

The Relationship Between Vitamin D deficiency and the severity of symptoms of Food Allergy inChildren

100481 2-H-W24-1-O/P

Miwa Sasai

Department of Immunoparasitology, Research Institute for Microbial Diseases, Osaka
University, Osaka, Japan<strong>Critical roles of GABARAPs on interferon-mediated cell-autonomous immune responses
against <em>T. gondii</em> infection</strong>

100168 2-H-W24-2-O/P

Mana Miyakoda

Division of Immunology, Department of Molecular Microbiology and Immunology,
Graduate School of Biomedical Sciences, Nagasaki University

Mechanisms underlying metformin-mediated enhancement of the protective immune responses against
malaria infection.

100361 2-H-W24-3-P

Takeshi Ono

Department of Global Infectious Diseases and Tropical Medicine, National Defense
Medical College

CD8<sup>+</sup> T cell immune responses during the <em>Plasmodium berghei</em> ANKA bloodstage infection

100238 2-H-W24-4-O/P

Sayuri Nakamae

Division of Immunology, Department of Molecular Microbiology and Immunology,
Nakgasaki University Graduate School of Biomedical Sciences, Nagasaki, Japan

Modulation of T-cell immune responses to pathogenic malaria parasites by prior infection with different
species of malaria parasites

100343 2-H-W24-5-P

Kenji Ishiwata

Department of Tropical Medicine, The Jikei University School of Medicine, Tokyo,Japan

T cell-dependent long-lasting blockade of mucosal penetration by infective larvae of a murine
gastrointestinal nematode100425 2-H-W24-6-P

Koubun Yasuda

Department of Immunology, Hyogo College of Medicine

IL-33-dependent resistance of <em>Strongyloides venezuelensis</em>-experienced mice against<em>Nippostrongylus brasiliensis</em> infection

100549 2-H-W24-7-O/P

Fumiji Saito

Research Institute for Microbial Diseases, Osaka University, Osaka, Japan<strong>Immune evasion of <em>Plasmodium falciparum</em> by RIFIN </strong><strong>via
inhibitory receptor</strong>

100017 2-H-W24-8-P

Risa Nakamura

Department of Parasitology, NEKKEN, Nagasaki University, Nagasaki, Japan

Type 2 innate lymphoid cells exacerbate severe amebic liver abscess in mice

100623 2-H-W24-9-P

Mizuho Tabata

Department of Parasitology and Infectious Diseases, Gifu University Graduate Schoolof Medicine, Gifu, Japan

Infection of parasitic nematode ameliorates imiquimod (IMQ)-induced psoriasis

16:00-17:00

Chang-Hyun Kim

16:00-17:00

100206 2-H-W24-10-O/P Odsuren Sukhbaatar

Department of Molecular Microbiology and Immunology, Nagasaki University Graduate
Role of Interleukin-27 in the regulation of immune responses against chronic malaria infection
School of Biomedical Science, Nagasaki, Japan

100580 2-H-W24-11-O/P Piyarat Srinontong

Department of Parasitology and Infectious Diseases, Gifu University Graduate Schoolof Medicine, Gifu, Japan

Regulation of Visceral Leishmaniasis by Secreted Immunoglobulin Deficiency

100219 2-H-W24-12-O/P Shin-Ichi Inoue

Department of Infectious Diseases, Kyorin University School of Medicine, Tokyo, Japan<strong>Maintenance of immunological memory to malaria is impaired by <em>Salmonella</em>
infection</strong>

100020 2-H-W24-13-P

Motoko Morimoto

School of Food, Agricultural, and Environmental Sciences, Miyagi University, Sendai
City, Miyagi, Japan

Antibiotic-induced changes in the intestinal microbiota affect the host resistance against helminths inmurine small intestine

100145 2-H-W24-14-P

Caroline M. Kijogi

Division of Immunology, Department of Molecular Microbiology and Immunology,
Graduate School of Biomedical Sciences, Nagasaki University, Nagasaki, Japan.

<strong>T-cell responses to <em>Plasmodium falciparum </em>and <em>Schistosoma mansoni</em>infections in asymptomatic children living in the endemic region of Mbita, western
Kenya.</strong>

7 / 13

The 46th Annual Meeting of The Japanese Society for Immunology

Session Title

W25

W26

W27

W28

Dendritic cells andMacrophages-1: Organspecific Immune
Tolerance

Tolerance and immune
suppression -1

Tolerance and immune
suppression -2

Innate Lymphocyte-1(NKT, MAIT, gdT, NK)

Date

Dec. 13(Wed.), 2017

Dec. 14(Thu.), 2017

Dec. 14(Thu.), 2017

Dec. 14(Thu.), 2017Time

16:00-17:00

Odd Number /16:00-17:00
Even Number /17:00-18:00

Odd Number /16:00-17:00
Even Number /17:00-18:00

Odd Number /16:00-17:00
Even Number /17:00-18:00

Submission ID

Program for Poster

Program No.

1st Author

Affiliation

Abstract Title

100018 2-I-W25-1-O/P

Tomofumi Uto

Division of Immunology, Department of Infectious Diseases, Faculty of Medicine,
University of Miyazaki, Miyazaki, Japan

100368 2-I-W25-2-O/P

Alessandro Nasti

System Biology, Kanazawa University, Kanazawa, Japan<strong>The CD45<sup>+</sup> subset in murine uncultured adipose tissue-derived stromal cells
features immune-inhibitory M2 macrophage-like cells</strong><strong> contributable for</strong><strong>therapeutics </strong><strong>of </strong><strong>acute h100094 2-I-W25-3-O/P

Hisako Kayama

Graduate School of Medicine, Osaka University, Suita, Japan

Spi-C inhibits expression of a subset of Toll-like receptor 4-inducible genes in intestinal
CX<sub>3</sub>CR1<sup>high</sup> macrophages and prevents colonic inflammation

100607 2-I-W25-4-O/P

Keita Aoi

Department of Immunology and Cell Biology, Graduate School of Medicine / Frontier
Biosciences, Osaka University, Osaka, Japan

Oral mucosa-specific macrophage subsets contribute to tolerance induction in sublingual
immunotherapy

100065 2-I-W25-5-O/P

Sho Sendo

Department of Rheumatology and Clinical Immunology, Kobe University Graduate
School of Medicine, Kobe, Japan.

<strong>CD11b<sup>+</sup>Gr1<sup>dim</sup> Tolerogenic Dendritic Cell-like Cells Differentiatedfrom Monocytic-MDSCs Suppress the Progression of Interstitial Lung Disease in SKG Mice</strong>

100459 2-I-W25-6-O/P

Yoshimitsu Nakanishi

Department of Respiratory Medicine and Clinical Immunology, Graduate School of
medicine, Osaka University, Osaka, Japan

Sema6D prevents excess inflammation during high-fat feeding by controlling mitochondrial metabolism.

100035 2-I-W25-7-P

Yo UedaDepartment of Rheumatology and Clinical immunology, Kobe University Graduate
School of Medicine, Kobe, Japan<strong>Inhibition of the mTOR Pathway and Glutaminolysis Facilitates the Expansion of MyeloidDerived Suppressor Cells and Synergistically Ameliorates Arthritis in SKG Mice</strong>

100025 2-I-W25-8-P

Yasuyuki Negishi

Department of Microbiology and Immunology, Nippon Medical School, Tokyo, Japan

Adoptive transfer of innate immune cells induce murine fetal loss

100171 2-I-W25-9-P

Hideki Minematsu

Katayama Chemical Industries Co.,Ltd, Osaka, Japan

Effects of liposome-encapsulated clodronate which can deplete macrophages <em>in vivo</em>.

100220 2-I-W25-10-P

Hiroki HIRAMA

Laboratory of Immunology, Graduate School of Health Sciences, Niigata University,
Niigata, JapanThe effects of ovariectomy on autoimmune hepatitis and hepatic dendritic cells.

100256 2-I-W25-11-P

Seiki Shirai

Laboratory of Nano-design for Innovative Drug Development, Graduate School of
Pharmaceutical Sciences, Osaka University

Development of dendritic cell-targeting peptides that induce antigen-specific immune tolerance

100555 2-I-W25-12-O/P

Matsumoto Minoru

Division of Molecular Immunology, Institute for Enzyme Research, Tokushima
University, Tokushima, Japan

Transgenic human AIRE expression in NOD acquired resistance to the diabetes due to the impaired
presentation of self-antigens in the pancreas

100550 2-I-W25-13-O/P

Yuta Shimizu

Department of Immunochemistry, Research Institute for Microbial Disease, Osaka
University, Laboratory of Immunochemistry

Chemical compounds that specifically inhibit aberrant MHC class II expression

100287 2-I-W25-14-P

Miya Yoshino

Division of Immunology, Department of Molecular and Cellular Biology, School of Life
Science, Faculty of Medicine, Tottori University, Yonago , Japan

Measurement of the transport of skin self-antigens under inflammatory conditions

100606 2-I-W25-15-P

Kouta Fujikura

Chiba Institute of Technology, Graduate School of Engineering, Department of Life andBioimaging Analysis for Endocytosis of macrophage in inframmation regulated by v-ATPase
Environmental Sciences, Narashino,Japan

100233 3-A-W26-1-O/P

Takumi Maruhashi

Division of Immune Regulation, Institute for Genome Research, Tokushima University, Immuno-inhibitory co-receptor LAG-3 regulates immunodominance and autoimmunity by virtue of its
Tokushima, Japan
conformation-dependent recognition of MHCII

100251 3-A-W26-2-O/P

Hikari Okamura

Division of Immune Regulation, Institute for Genome Research, Tokushima University

Single-cell analysis of autoreactive T cells under the control of PD-1

100595 3-A-W26-3-P

Ami Takahashi

Laboratory of Biomolecular Science, Faculty of Pharmaceutical Sciences, Hokkaido
University, Hokkaido, Japan

HLA-G2 gives immunosuppressive effects to human monocytes and dendritic cells

100166 3-A-W26-4-O/P

Daisuke Kimura

Division of Immunology, Department of Molecular Microbiology and Immunology,
Nagasaki University Graduate School of Biomedical Sciences, Nagasaki, Japan

Interleukin-27-dependent loss of CD4<sup>+</sup> T cell-memory during malaria infection

100130 3-A-W26-5-O/P

Shigenori Nagai

Department of Molecular Immunology, Tokyo Medical and Dental University, Tokyo,
Japan

PI3K-Akt pathway enhances type 1 regulatory T cell differentiation induced by IL-27

100354 3-A-W26-6-P

Hirotaka Kuwata

School of dentistry, Showa University, Tokyo, Japan

Microarray and gene co-expression analysis reveals that melatonin attenuates immune responses andmodulates actin rearrangement in macrophages.

100408 3-A-W26-7-P

Yuya Yoshida

Department of Pathological Biochemistry, Faculty of Pharmaceutical Sciences,
Setsunan University, Osaka, Japan

Induction of immune tolerance by combination treatment with fingolimod (FTY720) plus pathogenic
antigen in a glucose-6-phosphate isomerase peptide-induced arthritis mouse model: the fourth report100494 3-A-W26-8-P

Yuka Tanaka

Department of Gastroenterological and Transplant Surgery, Hiroshima University,
Hiroshima, Japan

Human endothelial-like cells transdifferentiated from peripheral CD14<sup>+</sup>monocytes inhibit T
cells in response to allo-stimulation

100536 3-A-W26-9-O/P

Xiaotong Cui

Laboratory of Infection and Prevention, Department of Virus Research, Institute for
Frontier Life and Medical Sciences, Kyoto University, Kyoto, Japan<strong>Interactions between Regnase-1 and Roquin Regulate Helper T Cell Polarization</strong>

100562 3-A-W26-10-O/P Kazuki Kishida

Department of Immunochemistry, Research Institute for Microbial Diseases, Osaka
University<strong>Antigen-specific immune regulation mediated by TCR-like antibodies</strong>

100076 3-A-W26-11-P

Cuiying He

Department of Immunology and Parasitology, University of Occupational andEnvironmental Health, Kitakyushu, Japan.

<strong>Urban particulate matter 2.5 induced immunosuppression in splenocytes is related withlipopolysaccharide level on particulate matter 2.5</strong>

100239 3-A-W26-12-P

Manabu Kinoshita

Department of Immunology and Microbiology, National Defense medical College,
Saitama, Japan<strong>LPS tolerance recruits CD11b<sup>+</sup> macrophages to the liver with enhanced
bactericidal activity and low TNF-releasing capability, resulting in drastic resistance to lethal
septicemia</strong>

100516 3-A-W27-1-O/P

Ryoji Kawakami

Immunology Frontier Research Center, Osaka university, Osaka, Japan

Epigenomic signatures of extrathymic-derived regulatory T-cells

100267 3-A-W27-2-P

Akane Hara

Graduate School of Systems Life Sciences, Kyushu University, Fukuoka, Japan

Theoretical study of relationship between allergy and intestinal microbiome.

100418 3-A-W27-3-P

Yuji Kashiwakura

Department of Immunology, Dokkyo Medical University School of Medicine, Mibu,
Tochigi, Japan

Heparin induces regulatory T cells by IL-2 production in mice

100589 3-A-W27-4-O/P

Yumi Yamashita-Kanemaru

Department of Immunology, Faculty of Medicine, University of Tsukuba, Tsukuba,
Ibaraki, JapanDNAM-1 limits Treg cell function via TIGIT-dependent manner100424 3-A-W27-5-P

Hidefumi Kojima

Department of Immunology, Dokkyo Medical University School of Medicine, Tochigi,
Japan

Fatty acids affect regulatory T cell metabolism and function during immune responses.

100442 3-A-W27-6-P

Chihiro Ohashi

Kitasato University School of Medicine, Sagamihara Japan

Spontaneous accumulation of myeloid-derived suppressor cell (MDSC)-like CD11b<sup>+</sup>/Gr1<sup>+</sup> cells in the periphery of NF-&kappa;B-inducing kinase (NIK) mutant mice.

100389 3-A-W27-7-O/P

Yoshiaki Yasumizu

Faculty of Medicine, Osaka University, Osaka, Japan

Significance of the regulatory T cell-specific epigenetics in autoimmune disease susceptibility

100460 3-A-W27-8-P

Sayuri Fukushima

Graduate School of Food, Agricultural and Environmental Sciences, Miyagi University, Specific expression of C3 components, C3b, iC3b with increase of IL-10 and TGF-&beta; in
Miyagi, Japanuterus&rsquo;s endometrium of mouse for the latter pregnant period

100470 3-A-W27-9-P

Naoko Negishi

Atopy (Allergy) Research Center, Juntendo University Graduate School of Medicine,Tokyo, Japan

CD155-mediated signaling through TIGIT is involved in serial transfer of tolerant state into na&iuml;ve T
cells

100578 3-A-W27-10-O/P Chikako Shimokawa

Department of Parasitology, Graduate School of Medicine, Gunma University, Gunma

Suppression of type 1 diabetes in mice infected with an intestinal nematode100510 3-A-W27-11-P

Tomoyuki Yamaguchi

Research Institute Nozaki Tokushukai, Osaka, Japan<strong>A simulation model of immune response predicts essential functions of Treg to maintain
immune tolerance</strong>

100570 3-A-W27-12-P

YUN GUO

Department of Immunology, Graduate School of Biomedical &amp; Health Sciences,
Hiroshima University, Hiroshima, Japan

Ubiquitin-modifying enzyme A20 plays a role in regulatory T cells

100633 3-A-W27-13-P

Yoshihiro Oya

Department of Rheumatology, Allergy &amp; Clinical Immunology National Hospital
Organization Chiba-East National Hospital , Chiba, Japan

Allo-specific Foxp3<sup>+</sup>CD4<sup>+ </sup>induced Tregs (allo-iTreg) suppress specificalloantigen, but not irrelevant alloantigen in vivo

100030 3-A-W27-14-O/P Hiroki Satooka

Department of Fundamental Biosciences, Shiga University of Medical Science, Shiga,Japan

The ERM protein moesin regulates CD8<sup>+</sup> regulatory T cell homeostasis and self-torelance

100564 3-A-W27-15-O/P Reiko Takahashi

Research Institute Nozaki Tokushukai, Daitou, Japan

Inhibition of melanoma proliferation by immunologic mechanism including the plasticity of SOCS1
deficient regulatory T cells

100334 3-B-W28-1-O/P

Shinya Hatano

Division of Host Defense, Medical Institute of Bioregulation, Kyushu University,
Fukuoka, Japan.

Development of new monoclonal antibody specific for murine V&gamma;6 chain

100075 3-B-W28-2-O/P

Tsukasa NabekuraLife Science Center, Tsukuba Advanced Research Alliance, University of Tsukuba,
Ibaraki, Japan

Tracking the fate of antigen-specific versus cytokine-activated natural killer cells after cytomegalovirus
infection

100597 3-B-W28-3-P

Maia Inoue

Department of Immunology, Graduate School of Medicine and Faculty of Medicine, The
A critical epigenetic regulator of early iNKT cell development
University of Tokyo, Tokyo, Japan

100395 3-B-W28-4-O/P

Eri Ishikawa

Department of Molecular Immunology, Research Institute for Microbial Diseases,
Osaka University, Osaka, Japan

A critical role of protein kinase D in NKT cell development

100286 3-B-W28-5-O/P

Hiroshi Watarai

Division of Stem Cell Cellomics, Institute of Medical Science, University of Tokyo<strong>A Novel Mouse Model of iNKT Cell-deficiency Generated by CRISPR/Cas9 Technology
Reveals a Pathogenic Role of iNKT Cells in Metabolic Disease</strong>

100653 3-B-W28-6-P

Kato Taiki

Kitasato University School of Medicine,Sagamihara,Japan

Tetramer-based analyses of antigen-specific T cells in relapse model of experimental autoimmune
uveoretinitis in mice

100487 3-B-W28-7-P

Masashi SATOH

Department of Immunology, Kitasato University, School of Medicine, Sagamihara,
Japan

Generation of CD1d-negative NKT-cell hybridomas

100495 3-B-W28-8-P

Shusaku Kobayashi

Department of Immunology, Kitasato University Graduate School of Medical Sciences,
Cardiac CD1d+ cells that present &alpha;-GalCer and activate NKT cells
Sagamihara, Japan

100511 3-B-W28-9-P

Iwayama Toshitsugu

Kitasato University School of Medicine, Sagamihara, Japan

Development of experimental autoimmune myocarditis model and experimental therapeutics with NKT
cell ligands

100057 3-B-W28-10-P

Masato Kamei

Department of Immunology, Juntendo University School of Medicine, Tokyo, Japan

MAIT cells exacerbate the disease course of oxazolone colitis.

100060 3-B-W28-11-O/P Goh Murayama

Department of Immunology, Juntendo University School of Medicine, Tokyo, Japan

Role of mucosal-associated invariant T cells in lupus pathogenesis

100392 3-B-W28-12-O/P Asako Chiba

Department of Immunology, Juntendo University, Tokyo, Japan

MAIT cells exacerbate the disease course of oxazolone colitis.

8 / 13

Critical role of plasmacytoid dendritic cells in the induction of oral tolerance for the control of allergic
sensitization

The 46th Annual Meeting of The Japanese Society for Immunology

Session Title

W29

W30

W31

Innate Lymphocyte-2(ILC1,2,3)

Dendritic cells andMacrophages-2:
Development andRecognition

Dendritic cells andMacrophages-3:
Inflammatory Responses

Date

Dec. 14(Thu.), 2017

Dec. 14(Thu.), 2017

Dec. 14(Thu.), 2017Time

Odd Number /16:00-17:00
Even Number /17:00-18:00

Odd Number /16:00-17:00
Even Number /17:00-18:00

Odd Number /16:00-17:00
Even Number /17:00-18:00

Submission ID

Program for Poster

Program No.

1st Author

Affiliation

Abstract Title

100566 3-B-W29-1-O/P

Takashi Ebihara

Laboratory for Transcriptional Regulation, RIKEN Center for Integrative Medical
Sciences

100448 3-B-W29-2-P

Koga Satoshi

Laboratory for Innate Immune Systems, RIKEN IMS, Kanagawa, Japan

Developmental trajectory of tissue-resident ILC2 from primary lymphoid organs to the peripheral
microenvironment

100465 3-B-W29-3-P

Yasutaka Motomura

Laboratory for Innate Immune Systems, RIKEN Center for Integrative Medical
Sciences, Yokohama, Japan

Regulation of ILC2-mediated antigen non-specific immune responses by cysteinyl leukotriene

100047 3-B-W29-4-O/P

Takanori So

Department of Microbiology and Immunology, Tohoku University Graduate School of
Medicine, Sendai, Japan

Early activation of group 2 innate lymphoid cells in the lung is critically controlled by the TNFR
superfamily molecule GITR

100147 3-B-W29-5-O/P

Natsuko Otaki

Laboratory for Innate Immune Systems, RIKEN IMS

The role of group 2 innate lymphoid cells in pulmonary fibrosis100435 3-B-W29-6-P

Tsutomu Yanagibashi

Toyama Prefectural Institute for Pharmaceutical Research, Toyama, Japan

IL-5-producing ILC2s in the large intestine contribute to T cell-independent IgA production through theregulation of eosinophil homeostasis100446 3-B-W29-7-O/P

Naoko SatohLaboratory for Intestinal Ecosystem, Center for Integrative Medical Science, RIKEN

Identification of an ILC2 population in the stomach which responds to commensal and pathogenic
bacteria

100476 3-B-W29-8-O/P

Takato Kobayashi

Laboratory for Innate Immune Systems, RIKEN IMSCharacterization of group 2 innate lymphoid cells in glandular tissue100468 3-B-W29-9-O/P

Mariko Kamioka

Division of Mucosal Immunology, Department of Microbiology and Immunology, The
Institute of Medical Science, The University of Tokyo, Tokyo, Japan

Innate and adaptive immune cells regulate Paneth cell granule formation and &alpha;-defensin
secretion

100157 3-B-W29-10-P

Shindo Ryodai

Toho University School of Medicine, Tokyo, Japan<strong>ROR&gamma;t-positive cells mediate RIPK3- and MLKL-dependent lethal ileitis in neonatal
mice</strong>

100427 3-B-W29-11-P

Daichi KOBAYASHI

Chiba Institute of Technology, Faculty of Engineering, Department of Life andEnvironmental Sciences. Narashino, Chiba, JapanThe effect of ILC3 regulated by glial cells in gut in inflammatory condition.

100436 3-B-W29-12-P

Shinichiro Sawa

Institute for Genetic Medicine, Hokkaido University, Sapporo, Japan

Development of novel mouse models lacking for group 3 innate lymphoid cells.

100237 3-C-W30-1-O/P

Jeong-Hwan Yoon

Biomedical Research Institute, Kyungpook National University Hospital, Daegu, Korea

Repression of SMAD3 by STAT3 and c-SKI is essential for conventional dendritic cell differentiation

100240 3-C-W30-2-O/P

Haruka Sasaki

Department of Immunology, Yokohama City University Graduate School of Medicine,
Yokohama, Japan

A novel distal enhancer responsible for <em>Irf8</em> expression in the mononuclear phagocyte
lineage

100622 3-C-W30-3-O/P

Nobuyuki Onai

Department of Immunology, Kanazawa Medical University, Ishikawa, Japan

Regulation of pDC development by graded expression of E2-2

100509 3-C-W30-4-P

Hideki Arimochi

Graduate School of Biomedical Sciences, Tokushima University, Tokushima, JapanFXR as a regulator of <em>Psmb8</em> expression is associated with macrophage differentiation

100027 3-C-W30-5-P

Hirofumi Miyazaki

Department of Organ Anatomy, Graduate School of Medicine, Tohoku University

FABP7 is involved in the M2 polarization of macrophages via mitochondrial fatty-acid oxidation

100289 3-C-W30-6-P

Hidetoshi Nara

Department of Immunology, Yamagata University Faculty of Medicine, Yamagata,
Japan

Interleukin21 arrests bone marrow derived dendritic cells PD-L1 high immunosuppressive state

100223 3-C-W30-7-P

Atsuo Nakamura

Dairy Science and Technology Institute, Kyodo Milk Industry Co. Ltd.,Tokyo, Japan<strong>Effect of polyamines on macrophage polarization and mucosal inflammation</strong>

100530 3-C-W30-8-P

Satoshi Fujiyama

Department of Immunology, Faculty of Medicine, University of Tsukuba , Ibaraki, Japan Identification of marginal zone macrophages by means of flow cytometry

100290 3-C-W30-9-O/P

Ryo Okada

Dept. of integrated Biosciences, Grad. school of frontier Sciences, The university ofTokyo, Tokyo, Japan

Distribution of DCIR4 among various tissue-resident macrophages

100369 3-C-W30-10-O/P Naoki Matsumoto

Graduate School of Frontier Sciences, the University of Tokyo, Chiba, Japan

Co-expression of DCIR3 and DCIR4 on monocytes

100500 3-C-W30-11-O/P Miyuki Watanabe

Department of Molecular Immunology, Research Institute for Microbial Diseases,
Osaka University, Osaka, Japan

Early FcR&gamma;-Erk signaling determines cytokine profile of dendritic cells through C-type lectin
receptors

100402 3-C-W30-12-O/P Shojiro Haji

Department of Molecular Immunology, Division of Host Defense, Research Institute for Recognition of lipids from <em>Helicobacter pylori</em> by dendritic cell immunoactivating receptor
Microbial Diseases, Osaka University, Osaka, Japan(DCAR).

100214 3-C-W30-13-O/P Masafumi Nakayama

Frontier Research Institute for Interdisciplinary Sciences, Tohoku University

Identification of a silica receptor associated with canonical inflammasome activation.

100260 3-C-W31-1-P

Yoshiyuki Miyazaki

Faculty of Agriculture, Kyushu University, Fukuoka, Japan

The induction of macrophage activation by a sulfated polysaccharide fucoidan

100531 3-C-W31-2-P

Tatsuo Katagiri

Department of (Pharm)Biology Graduate School of Medicine and Pharmaceutical
Sciences, University of Toyama, Toyama, Japan

Analysis of macrophage anti-tumor activating component derived from<em> Polyporus alveolaris</em>
extract (PAE)

100275 3-C-W31-3-P

Kazuko Atsumi

Department of Pathophysiological Laboratory Sciences, Nagoya University Graduate
School of Medicine, Nagoya, Japan<strong>Analysis on signal pathway in pro-inflammatory response by diazinon</strong>

100234 3-C-W31-4-P

Naho Ikari

Research &amp; Development Division, Kikkoman Corporation, Chiba, Japan

Double-stranded RNA in lactic acid bacteria augments Th1 immunity via IFN-&beta; secretion byhuman dendritic cells

100033 3-C-W31-5-O/P

Tanapat Palaga

Department of Microbiology, Faculty of Science, Chulalongkorn University, Bangkok,
Thailand

Notch Signaling Regulates Macrophages Activation by LPS in the Presence of Immune Complex

100148 3-C-W31-6-O/P

Sayako Chiba

Division of Gastroenterology and Hepatology, Department of Internal Medicine, Keio
University School of Medicine, Tokyo, Japan

Glycolysis regulates LPS-induced cytokine production in M2 polarized human macrophages

100149 3-C-W31-7-O/P

Akihiro KimuraDept. of Immunology and Pathology, Research Institute National Center for Global
Health and Medicine, Chiba, Japan<strong>The novel ubiquitin ligase complex, NQO1-PDLIM2 inhibits TLR-dependent production of
selective cytokines by degrading I&kappa;B-&zeta;</strong>

100252 3-C-W31-8-O/P

Rimpei MORITA

Department of Immunology, International University of Health and Welfare, School of
Medicine, Narita, Japan

Clathrin heavy chain is an NLRP3 partner for NLRP3 inflammasome activation

100167 3-C-W31-9-O/P

Takuya Yashiro

Department of Biological Science and Technology, Faculty of lndustrial Science andTechnology, Tokyo University of Science, Tokyo, Japan

Defect of NR4A3 leads to impaired ability of migration in intestinal dendritic cells

100269 3-C-W31-10-P

Shiori Nakano

Department of Biological Science and Technology, Faculty of Industrial Science andTechnology, Tokyo University of Science, Tokyo, Japan

NR4A3 is involved in function of migratory DCs and activation of T cells in FITC-induced contact
hypersensitivity

100303 3-C-W31-11-P

Yuna Uchida

Department of Biological Science and Technology, Tokyo University of Science, Tokyo,
The role of NR4A3 in the gene expression and function of dendritic cells
Japan

Runx proteins suppress constitutive activity of ILC2 and prevent ILC2 exhaustion after activation

100208 3-C-W31-12-O/P Takeshi Nakatani

Department of respiratory medicine and clinical immunology, Osaka Univ., Osaka,Japan

Lamtor1 (p18) plays a crucial role in trafficking of dendritic cells.

100416 3-C-W31-13-P

Natsuno Hama

Department of Biosciences, School of Science, Kitasato University, Kanagawa, Japan

Rap1 plays central role in adhesion and migration of DCs.

100163 3-C-W31-14-P

Mohamad Alaa Terkawi

Department of Orthopedic Surgery, Faculty of Medicine and Graduate School of
Medicine, Hokkaido University, Sapporo, Japan

Transcriptional profile of human macrophages stimulated by ultra-high molecular weight polyethylene
particulate debris of orthopaedic implants uncovers a common gene expression signature ofrheumatoid arthritis

100475 3-C-W31-15-O/P Takumi Kawasaki

Nara Institute of Science and Technology (NAIST), Nara, Japan<strong>Obesity regulation by PIKfyve, a lipid kinase, in macrophage</strong>

100341 3-C-W31-16-P

Hiroyuki Nakashima

Immunology and Microbiology, National Defense Medical College, 3-2 Namiki
Tokorozawa Saitama, Japan

Liver sinusoidal endothelial cells and resident Kupffer cells are involved in cholesterol metabolism inmice

100028 3-C-W31-17-P

Aya Ushio

Department of Oral Molecular Pathology, Graduate school of Biomedical Sciences,
Tokushima University, Tokushima, Japan

CCL22-producing resident macrophages enhances autoimmune lesions in a mouse model of
Sj&ouml;gren&rsquo;s syndrome

100572 3-C-W31-18-P

Noriko Mutoh

Department of Oral Interdisciplinary Medicine, Division of Pulp Biology, Kanagawa
Dental university, Yokosuka, Japan

Innate immune response induce the dentin regeneration in dental pulp

9 / 13

The 46th Annual Meeting of The Japanese Society for Immunology

Session Title

Tumor immunology-1(Tumor antigens, antigen
W32
presenting cells, antitumor T cells)

Date

Dec. 14(Thu.), 2017

Tumor immunology-2(Immunosuppression andDec. 14
W33
modulation in tumor(Thu.), 2017
immunity)

W34

B cell development andfunction

Dec. 14(Thu.), 2017Time

Odd Number /16:00-17:00
Even Number /17:00-18:00

Odd Number /16:00-17:00
Even Number /17:00-18:00

Odd Number /16:00-17:00
Even Number /17:00-18:00

Submission ID

Program for Poster

Program No.

1st Author

Affiliation

Abstract Title

100190 3-D-W32-1-O/P

Yasuhiro Kikuchi

Department of Pathology, Sapporo Medical University School of Medicine, Sapporo,
Japan

100174 3-D-W32-2-P

Ayumi Hongo

Department of Pathology, Sapporo Medical University, Sapporo, Japan

Presence of proline in N-terminal extensions of epitope sequences influences HLA-A24 antigen
processing and decreases CD8+ T-cell responses

100337 3-D-W32-3-P

Taro Kikuchi

Department of Pathology, Sapporo Medical University, Sapporo, JapanCTL responses against cancer with an MHC class I antigen-processing defect100362 3-D-W32-4-O/P

Yoh Ohnuki

Department of Immunology, Graduate School of Medicine and Pharmaceutical
Sciences, University of Toyama, 2630 Sugitani, Toyama 930-0194, JapanThe model of antigen detection system using yeast surface display library

100648 3-D-W32-5-P

Kiyoshi Yoshimura

National Cancer Center, Tokyo, Japan

Identification and analysis about molecules which are highly expressed in pancreatic cancer stem-likecells

100626 3-D-W32-6-O/P

Keisuke Fujii

Department of Immuno-Gene Therapy, Mie University Graduate School of Medicine,Mie, Japan

Phenotypic and clonality analysis of tumor-reactive CD8<sup>+</sup> T cells among TILs in humancolorectal tumor tissue100507 3-D-W32-7-O/P

Taiki Moriya

Laboratory of Immunology, Faculty of Pharmacy, Osaka Ohtani University, Osaka,Japan

Tumor cell death induction enhances tumor infiltrating dendritic cell migration and increases in tumor
antigen-specific T cells.

100106 3-D-W32-8-P

Shinsuke Nakajima

Division of Immunology and Molecular Biology, Cancer Research Institute, Kanazawa
University, Ishikawa, Japan

Caspase-1-induced pyroptosis potentiates anti-tumor immunity

100038 3-D-W32-9-O/P

Takuto Nosaka

Second Department of Internal Medicine, Faculty of Medical Sciences, Fukui
University, Eiheiji-machi, Japan<strong>Alveolar macrophages drive hepatocellular carcinoma lung metastasis in collaboration withinterstitial macrophages</strong>

100421 3-D-W32-10-O/P Risa Fujii

Department of Anatomy and Embryology, Faculty of medicine, University of Tsukuba,
Tsukuba, Japan<strong>MafB inhibits tumor growth through regulating</strong> <strong>Tumor-Associated&ndash;Macrophages in spleen</strong>

100186 3-D-W32-11-O/P Hisashi Kanemaru

Research Institute for Microbial Diseases (RIMD), Osaka University, Osaka, Japan

Basic leucine zipper transcription factor ATF-like 2 exhibits an anti-tumor effect through upregulation of
IL-12 p40 expression

100098 3-D-W32-12-P

Hidemi Takahashi

Department of Microbiology and Immunology, Nippon Medical School, Tokyo, Japan<strong>Suppression of murine tumor growth through CD8+ CTLs via activated DEC-205+ dendritic
cells by sequential administration of &alpha;-galactosylceramide in vivo: A possible mechanism for
SSM (Maruyama Vaccine)</strong>

100453 3-D-W32-13-P

Yui Kuroki

Reserch Institute for Biomedical Sciences,Tokyo University of Science

Analysis of antigen prosenting cells that inducec CD8+ CD11c+ T cells in tumor microenviroment100469 3-D-W32-14-O/P Hiroshi HIGUCHI

School of Medicine, Tokai University, Kanagawa, Japan

Phosphatidylserine-mediated incorporation of tumor-derived exosomes and phenotypic changes inhuman macrophages

100599 3-D-W32-15-P

Masaki Tamiya

Division of Cell signaling, Institute for Advanced Medical Research, Keio University
school of Medicine

Reversal of anti-PD-1/PD-L1 therapy resistance by modulation of tumor-associated macrophages using
CSF-1 receptor blockade

100032 3-D-W32-16-P

Naosuke Morikawa

Graduate School of Pharmaceutical Sciences, Osaka University, Osaka, Japan<strong>LY341495, an mGluR2/3 antagonist, attenuates the immunosuppressive function of myeloidderived suppressor cells and inhibits the melanoma tumor growth.</strong>

100432 3-D-W32-17-P

Yui Ezaki

Department of Immunology,Kurume University School of Medicine<strong>Chitinase 3-like 1</strong><strong> (CHI3L1/YKL-40)</strong><strong> induces carcinogenic
changes of epithelial cells by promoting cell survival and proliferation under in vitro and in vivo
conditions</strong>

100574 3-D-W33-1-O/P

Okumura Genki

Department of Immunology, Faculty of medicine, University of Tsukuba

The role of soluble CD155 in tumor immune response and metastasis100299 3-D-W33-2-O/P

Ibuki Harada

Department of Immunology, Yokohama City University Graduate School of Medicine,
Yokohama, Japan<strong>Soluble factors produced by BCR-ABL-positive leukemic cells may compromise antitumor
immunity in chronic myeloid leukemia </strong>

100404 3-D-W33-3-O/P

Hirotake Tsukamoto

Department of Immunology, Graduate School of Medical Sciences, Kumamoto
University, Kumamoto, Japan<strong>Combined blockade of IL-6 and PD-L1 signals breaks a mutual regulation of theirimmunosuppressive effects on anti-tumor immunity</strong>

100462 3-D-W33-4-O/P

Haruka Wada

Division of Immunobiology, Institute for Genetic Medicine, Hokkaido University

Tumor initiating cell in immunocompetent animal defined by immunological features

100055 3-D-W33-5-O/P

Chie Kudo-Saito

Department of Immune Medicine, National Cancer Center Research Institute, Tokyo,
Japan<strong>Targeting the pathogenic mesenchymal stromal/stem cells prevents immune
exhaustion</strong>

100634 3-D-W33-6-O/P

Aya Hirata

Department of Immune Medicine, National Cancer Center Research InstituteEffect of Imatinib mesylate to tumor immunosuppressive microenvironment

100387 3-D-W33-7-P

Mikako Nishida

Department of Immunology, Graduate School of Medicine, Dentistry andPharmaceutical Sciences, Okayama University, Okayama, Japan

Anti-oxidative stress response is involved in Metformin-induced anti-tumor immunity

100114 3-D-W33-8-O/P

Marija Mojic

Division of Pathogenic Biochemistry Institute of Natural Medicine, University of
Toyama, Toyama, Japan<strong>Tumor-specific CTL&#39;s reduced clonality and proliferation index, not the inhibitory immune
checkpoint expression, as hallmarks of B16 melanoma immune evasion</strong>

100575 3-D-W33-9-O/P

Satoshi Ueha

Department of Molecular Preventive Medicine, Graduate School of Medicine, The
University of Tokyo, Tokyo, JapanTCR sequencing reveals the generation and expansion of tumor-specific CD8<sup>+ </sup>T cellclones after anti-CD4 antibody treatment in tumor-bearing mice

100185 3-D-W33-10-P

Wakana Goto

Laboratory of Hematology and Oncology, Graduate School of Health Sciences, Niigata<strong>Clonal amplification of WT1 specific CTL using dendritic cell line.</strong>
University, Japan

100380 3-D-W33-11-P

Asuka Miyamoto

Department of Molecular Life Science, Tokai University School of Medicine, Isehara,
Kanagawa, Japan

100514 3-D-W33-12-P

Makoto Tsuiji

Department of Microbiology, Hoshi University School of Pharmacy and Pharmaceutical
Effects of linoleic acid oxide 13-HODE and 13-HPODE on immune responses.
Sciences

100612 3-D-W33-13-P

Yoshinori TAKAHASHI

Department of Pulmonary and Critical Care Medicine, Mie University Hospital, Japan

Biomarkers including circulating PD-L1 and PD-1 in human (L858R) EGFR mutant transgenic micewith lung cancer

100420 3-D-W33-14-P

Yuetsu Tanaka

Department of Immunology, Graduate School of Medicine, University of the Ryukyus,
Okinawa, Japan

The importance of fixation/permeablization methods for flow cyotometric detection of human FoxP3
antigen as examined using human Treg and non-Treg cell lines transformed by HTLV-I

100139 3-D-W33-15-P

Naoko Kumagai-Takei

Department of Hygiene, Kawasaki Medical Scool, Kurashiki, JapanThe analysis for function of human CD8+T cell line with and without long-term exposure to asbestos
fibers100332 3-D-W33-16-P

Yasumitsu Nishimura

Department of Hygiene, Kawasaki Medical School

Secretory factors produced by immune cells upon exposure to asbestos facilitate proliferation ofmesothelial cells

100103 3-E-W34-1-O/P

Sachiko Hirose

Toin Human Science and Technology Center, Department of Biomedical Engineering,Toin University of Yokohama, Yokohama, Japan<strong>Independent effect of inhibitory </strong><strong>IgG Fc receptor</strong> <strong>IIB
on</strong><strong> B cells and monocytes </strong><strong>on <em>Yaa</em>-induced murine
lupus</strong>

100198 3-E-W34-2-O/P

Hisashi Nomura

Department of Dermatology, Keio University School of Medicine, Tokyo, Japan

Fc&gamma;RIIb plays an important role in maintaining clonal ignorance and prevents pemphigus
phenotype in pathogenic anti-desmoglein 3 antibody knock-in mice

100386 3-E-W34-3-O/P

Hitomi Sakatani

Nara Institute of Science and Technology, Nara, Japan

Novel compounds that induce specifically class switching to IgA

100489 3-E-W34-4-O/P

Saori Fukao

Research Institute for Biomedical Sciences, Tokyo University of Science, Chiba, Japan Regulation of IgE production by an RNA binding protein

100315 3-E-W34-5-O/P

Akihiko Muto

Department of Biochemistry, Tohoku University Graduate School of Medicine, Miyagi,
Japan

Single-cell analysis of gene regulatory network in activated B cells

100613 3-E-W34-6-O/P

Adachi Takahiro

Department of Immunology, Medical Research Institute, Tokyo Medical and Dental
University, Tokyo, Japan

Intravital imaging of Ca<sup>2+</sup> signals in lymphocytes of the Ca<sup>2+</sup> biosensor
YC3.60 transgenic mice

100089 3-E-W34-7-O/P

Mineto Ota

The Department of Allergy and Rheumatology, Graduate School of Medicine, The
University of Tokyo, Tokyo, Japan

Abnormal B cell receptor repertoire maturation in SLE unveiled by RNA sequencing of immune cells

100043 3-E-W34-8-O/P

Tsubasa Okano

Maternal B cells, engrafted in patients with X-linked severe combined immunodeficiency (X-SCID),
Department of Pediatrics and Developmental Biology, Graduate School of Medical andcould undergo class switch recombination without somatic hypermutation and cause IgG1
Dental Sciences, Tokyo Medical and Dental University (TMDU), Tokyo, Japan
gammopathy.

100230 3-E-W34-9-P

Hanbing Xue

Graduate School of Life and Environmental Sciences, University of Tsukuba, Ibaraki,Japan

Examination of &ldquo;Universal Light Chain&rdquo; models that can be paired with a wide spectrumof immunoglobulin heavy chains maintaining their antigen-binding specificities

100159 3-E-W34-10-P

Shoya Yasuda

Department of Computational Intelligence and Systems Science, Tokyo Institute ofTechnology, Yokohama, Japan

Mathematical modeling of BAFFR-mediated B cell survival signa

100410 3-E-W34-11-P

Ryouma Totera

Narashino, Chiba , Japan

Cultured B cells and Immune globlulin gene expression.

100429 3-E-W34-12-P

Ryouma KOTERA

Chiba Institute of Technology, Graduate School of Engineering, Department of Life and T cell dependent and independent regulation on immune globulin gene expressions in vitro B cell
Environmental Sciences, Tsudanuma, Chiba ,Japandifferentiation

100523 3-E-W34-13-P

Nazim Medzhidov

Department of Immunology, Medical Research Institute, Tokyo Medical and Dental
University, Tokyo, Japan<strong>Role of poor B cell receptor ubiquitination in efficient antigen presentation</strong>

100581 3-E-W34-14-P

Yangyang Feng

Department of Immunology, Medical Research Institute, Tokyo Medical and Dental
University<strong>Role of NADPH oxidases in BCR ligation-induced ROS production and activation</strong>

100272 3-E-W34-15-P

Miyoko Matsushima

Department of Pathophysiological Laboratory Sciences, Nagoya University Graduate
School of Medicine, Nagoya, Japan<strong>Deteriorated amount of IC capture without CD40 on B cells</strong>

100295 3-E-W34-16-P

Haruka Saito

Department of Biosciences, School of Science, Kitasato University, Kanagawa, Japan

Rab13 prevents development of B cell lymphoma

10 / 13

A novel HLA class I peptide encoded by a long non-coding RNA

Production of specific IgG against HER2 peptide is decreased in NOG-IL4-Tg mice transplanted withbreast cancer patients PBMC

The 46th Annual Meeting of The Japanese Society for Immunology

Session Title

Germinal center reaction
W35
and plasma cells

DateDec. 14(Thu.), 2017

Dec. 14
W36 Mucosal-Skin Immunity-2(Thu.), 2017

W37 Mucosal-Skin Immunity-3

W38

Systemic autoimmune
disease (2)Dec. 14(Thu.), 2017

Dec. 14(Thu.), 2017Time

Odd Number /16:00-17:00
Even Number /17:00-18:00

Odd Number /16:00-17:00
Even Number /17:00-18:00

Odd Number /16:00-17:00
Even Number /17:00-18:00

Odd Number /16:00-17:00
Even Number /17:00-18:00

Submission ID

Program for Poster

Program No.

1st Author

Affiliation

Abstract Title

100426 3-E-W35-1-O/P

Katsuya Sato

Department of Molecular Pathobiochemistry, Gifu University School of Medicine, Gifu,
Japan

100126 3-E-W35-2-O/P

Mayuko Shimoda

Laboratory of Host Defense, Research Institute for Microbial Diseases Osaka
University, Suita, Osaka, Japan

100610 3-E-W35-3-O/P

Kei Haniuda

Research Institute for Biomedical Sciences, Tokyo University of Science, Chiba, Japan Germinal center B cell development by glycolysis and mitochondrial metabolism

100585 3-E-W35-4-O/P

Wataru Ise

Immunology Frontier Research Center, Osaka University, Osaka, Japan

100598 3-E-W35-5-O/P

Atsuko Kayaba

Department of Experimental Immunology, Institute of Development, Aging and Cancer, PIR-B suppresses IL-6 secretion from mesenchymal stem cells and regulates the immunoglobulin
Tohoku University, Sendai, Japanproduction of plasma cells.

100527 3-E-W35-6-O/P

Ari Itoh-Nakadai

Department of Experimental Immunology, Institute of Development, Aging and Cancer,
Secretory leukocyte peptidase inhibitor (SLPI) is highly expressed in long-lived plasma cells
Tohoku University, Tokyo, Japan

100636 3-E-W35-7-O/P

Koji Tokoyoda

Deutsches Rheuma-Forschungszentrum Berlin (DRFZ), Berlin, Germany<em>Salmonella</em> remotely suppresses long-lasting humoral immunity

100374 3-E-W35-8-O/P

Katsuki Usami

International Education and Research Center for Food and Agricultural Immunology,
Graduate School of Agricultural Science, Tohoku University, Miyagi, Japan

Important role of the immunological network between large intestine and mammary gland inbreastfeeding

100406 3-E-W35-9-O/P

Hirohiko Ono

National Center of Neurology and Psychiatry National Institute of Neuroscience,
Department of Immunology, Tokyo, Japan

Dysregulated B cells in Myalgic encephalomyelitis/Chronic Fatigue Syndrome

100245 3-E-W35-10-P

Mizuki Ishikawa

Akita University, Graduate School of Engineering Science, Laboratory for Molecular
Cell Physiology, Akita, Japan

Regulatory mechanism for intracellular sorting of Parm1 by NPxY motif.

100326 3-F-W36-1-O/P

Akira Nakajima

Center for Innovation in Immunoregulative Technology and Therapeutics, Graduate
School of Medicine, Kyoto University<strong>Mucus-associated functional factors in Bacteroidetes promotes inter-phylum</strong><strong>symbiosis and colonic homeostasis</strong>

100338 3-F-W36-2-P

Junko Nishio

Institute of Industrial Science, The University of Tokyo, Tokyo, Japan

Surfactant protein D directly binds to gut bacteria and regulates microbiota composition for intestinal
homeostasis100344 3-F-W36-3-O/P

Eiji Miyauchi

Laboratory for Intestinal Ecosystem, IMS, RIKEN, Yokohama, Japan

Mimicry peptides from gut commensals stimulate myelin-specific T cells and exacerbate experimental
autoimmune encephalomyelitis

100621 3-F-W36-4-P

Ichiro Takahashi

Department of Mucosal Immunology, Dental School, Hiroshima University, Hiroshima,
Japan

Metabolic demand of colonic macrophages for symbiotic and cytosolic colonization by non-lymphoidtissue resident commensal bacteria

100660 3-F-W36-5-O/P

Takashi Tanaka

Laboratory for Inflammatory Regulation, REKEN Center for Integrative Medical
Sciences, Yokohama, Japan<strong>Microbiota-dependent development of non-alcoholic steatohepatitis (NASH) in PDLIM2deficient mice</strong>.

100541 3-F-W36-6-P

Toshiyuki Kojima

Department of Immune Regulation, Tokyo Medical and Dental University, Tokyo,
Japan.

Novel CD200 homologues iSEC1 and iSEC2 are gastrointestinal secretory cell-specific ligands ofinhibitory receptor CD200R

100559 3-F-W36-7-P

Masako Kohyama

Department of Immunochemistry, Research Institute for Microbial Diseases, Osaka
University

Intestinal epithelial homeostasis regulated by CD74

100608 3-F-W36-8-P

Terufumi Kubo

Department of Pathology, Sapporo Medical University School of Medicine, Sapporo,Japan

Differential bronchial epithelial response regulated by deltaNp63: a potential mechanism explaining
chronicity of asthma

100052 3-F-W36-9-O/P

Masaaki HASHIGUCHI

Department of Immunology, Dokkyo Medical University School of Medicine, Mibu,
Tochigi, Japan

Tumor necrosis factor superfamily member (TNFSF) 13, APRIL and TNFSF13B, BAFF downregulate
homeostatic immunoglobulin production in intestines

100217 3-F-W36-10-P

Katsuhiro NakanishiLaboratory of Microbiology and Immunology, School of Pharmaceutical Sciences,
University of Shizuoka, Shizuoka, Japan

Production of secretory hybrid-IgG/IgA in plant expression system

100243 3-F-W36-11-O/P

Tadashi Takeuchi

Laboratory for Intestinal Ecosystem, RIKEN Center for Integrative Medical Sciences

Gut microbial metabolite acetate modulates affinity of IgA to maintain intestinal homeostasis100457 3-F-W36-12-P

Naoya Tsugawa

Department of Gastroenterology, Graduate School of Medical Science, Tokyo Medical
and Dental University, Tokyo, Japan<strong>Verification of immunoglobulin A regulation of mucosal microflora and homeostasis</strong>

100464 3-F-W36-13-P

Takashi Nagaishi

Department of Gastroenteroogy, Graduate School of Medical Science, Tokyo Medical
and Dental University<strong><em>XXX</em></strong>

100293 3-F-W36-14-O/P

Mayuri Tanaka

Laboratory of Adjuvant Innovation, Center for Vaccine and Adjuvant Research, National
Essential role of CARD14 in murine experimental psoriasis
Institutes of Biomedical Innovation, Health and Nutrition, Osaka, Japan

100364 3-F-W36-15-P

Noriko Sato

Dept. of Plastic and Reconstructive surgery, Tohoku Univ.

Effect of Mincle deficiency on the wound healing process in skin100485 3-F-W36-16-P

Takayuki MIURA

Deptartment of Plastic and Reconstructive Surgery, Tohoku University, Sendai, Japan

Effect of Dectin-2-mediated signaling on skin wound healing and NETosis

100601 3-F-W36-17-O/P

Saeko Nakajima

Department of Dermatology, Kyoto University Graduate School of Medicine<em>Candida albicans</em> skin colonization exacerbates the inflammation of murine psoriasis-likedermatitis

100624 3-F-W36-18-O/P

Gyohei Egawa

Department of Dermatology, Kyoto University Graduate School of Medicine, Kyoto,Japan<strong>Revisiting the concept of CHS response; effector T cells infiltrates into the hapten-entry sites
and confer long-lasting local memory</strong>

100323 3-F-W37-1-O/P

Hiroe Tetsu

Laboratory for innate Immune Systems, RIKEN, IMS, Japan

Role of group 2 innate lymphoid cells in the skin100396 3-F-W37-2-P

Weng Sheng Kong

Department of Immunology, Graduate School of Biomedical and Health Sciences,
Hiroshima University, japan

Analysis of gut and skin inflammation in the pathogenesis of atopic dermatitis

100504 3-F-W37-3-P

Ryoki Kobayashi

Nihon University, School of Dentistry at Matsudo, Chiba, Japan

Characterization of Innate lymphoid cells in inflamed gingiva of mice infected with <em>Porphyromonas
gingivalis</em>

100486 3-F-W37-4-O/P

Chieko Ishifune

Department of Immunology and Parasitology, Institute of Biomedical Sciences,
Tokushima University Graduate School, Tokushima, Japan

Notch signal controls the number of
TCR&alpha;&beta;<sup>+</sup>CD8&alpha;&alpha;<sup>+</sup> intraepithelial lymphocytes via
phospholipid asymmetry by maintaining fllipase ATP8a2

100539 3-F-W37-5-P

Taku Naito

Department of Molecular Immunology, Toho University School of Medicine, Tokyo,
Japan

Maintenance of intestinal homeostasis by T cell-expressed Eed.

100175 3-F-W37-6-O/P

Hideaki Takagi

Division of Immunology, Department of Infectious Diseases, Faculty of Medicine,
University of Miyazaki

Tolerogenesis of gastrointestinal plasmacytoid dendritic cells impacts the induction of oral tolerance

100253 3-F-W37-7-O/P

Takashi Kanaya

Laboratory for Intestinal Ecosystem, RIKEN Center for Integrative Medical Sciences,
Yokohama, Kanagawa, Japan

IL-22 binding protein (IL-22BP) regulates the properties of follicle-associated epithelium (FAE) tofacilitate antigen uptake into Peyer&rsquo;s patches

100086 3-F-W37-8-P

Tomomi Hashizume-Takizawa

Nihon University School of Dentistry at Matsudo, Chiba, Japan

Surface IgA<sup>+</sup> Peyer&rsquo;s patch B cells play key roles for induction of recombinant<em>Salmonella</em>-derived antigen-specific intestinal IgA antibody responses

100584 3-F-W37-9-P

Hisashi Ueta

Department of Anatomy (Macro), Dokkyo Medical University, Tochigi, Japan

Peyer&rsquo;s patch functions as a transition site for rapid recirculation of lymphocytes during gut
immunosurveillance: multicolor immunohistochemical study

100651 3-F-W37-10-P

Lisa Fujimura

Biomedical Research Center, Chiba University, Chiba, Japan

Roles of enteric neurons in gut mucosal immunity.

100639 3-F-W37-11-O/P

Kamachi Fumitaka

Department of Applied Biological Science, Faculty of Science and Technology, Tokyo
University of Science, Chiba, Japan

Effects of gut microbial metabolites of linoleic acid on cytokine profuction by immune cells

100388 3-F-W37-12-O/P

Motoyoshi Nagai

Graduate School of Pharmaceutical Science, Keio University, Tokyo, Japan

Nutritional signals are essential for the regulation of cell dynamics and mucosal immune response in
GALT

100558 3-F-W37-13-P

Sachi Tanaka

Graduate School of Agriculture, Shinshu University, Nagano, Japan

Caloric restriction ameliorates dextran sulfate sodium-induced colitis in mice

100155 3-F-W37-14-P

Hideo Kataoka

Department of Oral Microbiology, Showa University School of Dentistry, Tokyo, JapanMALDI-TOF-MS Analysis of gut microbiota in murine model of food allergy

100221 3-F-W37-15-O/P

Hidehiko Suzuki

Laboratory of Vaccine Materials and Laboratory of Gut Environmental System, National Development of divalent food poisoning vaccine by augmented antigenicity of <em>Clostridium
Institutes of Biomedical Innovation, Health and Nutrition (NIBIOHN)
perfringens</em> enterotoxin

100560 3-F-W37-16-P

Naoki Takemura

Department of Mucosal Immunology, School of Medicine, Chiba University, Chiba,
Japan

Prime-boost vaccination with CpG ODN and curdlan strongly induces both systemic and mucosal
immunity

100452 3-F-W37-17-O/P

Hideki Asanuma

National Institute of Infectious Diseases, Tokyo, JAPAN<strong>Essential roles for protective SIgA Abs induced by nasal G9.1 combined influenza VLP
vaccine</strong>

100273 3-F-W37-18-P

Yuki Kanai

Laboratory of Nano-design for Innovative Drug Development, Graduate School of
Pharmaceutical Sciences, Osaka University

Pulmonary vaccine against lung cancer developed using dendritic cell-targeting peptide

100125 3-F-W37-19-P

Naoto Yoshino

Division of Infectious Diseases and Immunology, Department of Microbiology, Schoolof Medicine, Iwate Medical University, Iwate, Japan

Mucosal adjuvanticity of surfactin correlates with the surface-active property

100127 3-G-W38-1-O/P

Shigeru Iwata

The First Department of Internal Medicine, School of Medicine, University ofOccupational &amp; Environmental Health, Japan, Kitakyushu, Fukuoka, Japan<strong>IFN-</strong><strong>&gamma;</strong><strong>-T-bet mediated metabolic reprograming inT</strong> <strong>helper 1 cells</strong><strong>and </strong><strong>its relevance topathogenesis of SLE</strong>

100023 3-G-W38-2-O/P

Maiko Okumura

1st Department of Internal Medicine, Graduate School of Medicine and Pharmaceutical Production of Ro52/TRIM21 autoantibodies that react to PEP08 epitope in Ro52 clinically relate to the
Sciences (Medicine), University of Toyama
morbidity and severity of interstitial lung disease in connective tissue diseases.

100156 3-G-W38-3-O/P

Yusuke Takeshima

1Department of Allergy and Rheumatology, Graduate School of Medicine, theUniversity of Tokyo, Tokyo, Japan

Comprehensive analysis of genome and transcriptome analysis of immune cell subsets in peripheral
blood mononuclear cells (PBMCs) revealed mitochondria contribution in B cells to systemic lupus
erythematosus.

100331 3-G-W38-4-O/P

Natsumoto Bunki

Department of Allergy and Rheumatology, Graduate School of Medicine, The
University of Tokyo, Japan

Pathophysiological analysis of systemic lupus erythematosus (SLE) using patient-derived induced
pluripotent stem cells

100151 3-G-W38-5-P

Kato Yasuhiro

Department of Respiratory Medicine and Clinical Immunology, Graduate School of
Medicine, University of Osaka, JapanThe role of Stimulator of interferon genes (STING) in the pathogenesis of SLE

100307 3-G-W38-6-O/P

Yukiko Iwasaki

Department of Allergy and Rheumatology, Graduate School of Medicine, The
University of Tokyo, Japan

Plasma metabolomic analysis combined with transcriptome data has potential for stratification of SLE
patients

100552 3-G-W38-7-O/P

Yuki Sasagawa

Laboratory of Immunochemistry, WPI Immunology Frontier Reseach Center, Osaka
University, Osaka, Japan

Antiphospholipid antibody recognizes &beta;2GPI complexed with HLA class II molecules via its
domain V

100573 3-G-W38-8-O/P

Satoko Morikami

Department of Obstetrics and Gynecology, Kobe University Graduate School of
Medicine, Hyogo, Japan

Prothrombin complexed with HLA class II molecules is an autoantibody target in antiphospholipid
syndrome

11 / 13

Analysis of cis-regulatory elements involved in the regulation of expression of <em>Aicda</em><strong>GANP maintains antibody structural integrity during somatic hypermutation</strong>

The heightened T-B interaction associates with plasma-prone germinal center B cells

The 46th Annual Meeting of The Japanese Society for Immunology

Session Title

W39

Systemic autoimmune
disease (3)W40 Granulocyte & Mast cells

W41

Tissue-specific immune
diseases III

Date

Dec. 14(Thu.), 2017

Dec. 14(Thu.), 2017

Dec. 14(Thu.), 2017Time

Odd Number /16:00-17:00
Even Number /17:00-18:00

Odd Number /16:00-17:00
Even Number /17:00-18:00

Odd Number /16:00-17:00
Even Number /17:00-18:00

Submission ID

Program for Poster

Program No.

1st Author

Affiliation

Abstract Title

100083 3-G-W39-1-P

Tatsuhiko Ozawa

Department of Immunology, Graduate School of Medicine and Pharmaceutical
Sciences, University of Toyama, Toyama, Japan

Evolution of anti-citrullinated peptide antibody (ACPA): analysis of autoantigen under native condition
using a human monoclonal ACPA

100071 3-G-W39-2-P

Shizuyo Tsujimura

The First Department of Internal Medicine, School of Medicine University ofOccupational and Environmental Health, Kitakyushu, Japan<strong>The Characteristic of the P glycoprotein expression on the B cell subsets in rheumatoid
arthritis</strong>

100236 3-G-W39-3-P

Shinji Maeda

Department of Respiratory Medicine, Allergy and Clinical Immunology, Nagoya City
University Graduate School of Medical Sciences<strong>Exploratory study of T cell biomarkers predicting Abatacept treatment response in RA patientswith background adjustment by IPW method</strong>

100222 3-G-W39-4-O/P

Haruka Tsuchiya

Department of Allergy and Rheumatology, The University of Tokyo, Tokyo, Japan

Identification EP300 as a Novel Therapeutic Target for Rheumatoid Arthritis by the Comprehensive
Analysis of Fibroblast-like Synoviocytes

100255 3-G-W39-5-O/P

Shinsuke Yasuda

Department of Rheumatology, Endocrinology and Nephrology, Faculty of Medicine and <strong>RasGRP-Ras-MAPK activation in </strong><strong>fibroblast-like synoviocytes from patients
Graduate School of Medicine, Hokkaido University, Sapporo, Japan
with rheumatoid arthritis and inhibition of this pathway by Ras translocation</strong>

100502 3-G-W39-6-P

Hidekata Yasuoka

Division of Rheumatology, Department of Internal Medicine, Keio University School of
Medicine, Tokyo, Japan

Phenotype of platelet is altered in circulation of patients with rheumatoid arthritis

100036 3-G-W39-7-O/P

Harumi Shirai

Department of Allergy and Rheumatology, Graduate School of Medicine, The
University of Tokyo, Tokyo, Japan

Investigation of pathogenesis of Adult onset Still&rsquo;s disease through lymphocyte subsets analysis
in peripheral blood followed by RNA-sequencing

100084 3-G-W39-8-O/P

Noriko Arase

Department of Immunochemistry, Research Institute for Microbial Diseases, Osaka
University

Recognition of SS-A/IgG/HLA-DR complex by autoantibodies in Sjogren&rsquo;s syndrome

100132 3-G-W39-9-O/P

Yoshinobu Koyama

Center for Autoimmune Diseases, Division of Rheumatology, Japan Red Cross
Okayama Hospital,Okayama, Japan

Exercise-induced pulmonary hypertension at early stage of systemic sclerosis: changes in gene
expression of peripheral blood cells

100480 3-G-W39-10-O/P Yoshimichi Okayama

Autoantibodies (AAbs) against the Fc&epsilon;RI &alpha;-chain and IgE in patients with chronic
Allergy and Immunology Research Project Team, Center for Institutional Research andspontaneous urticaria (CSU) induced statistically higher ability of Fc&epsilon;RI aggregation compared
Medical Education, Nihon University School of Medicine
with non-atopic control (NC) subjects

100314 3-G-W39-11-O/P Sugimori Yusuke

Department of Allergy and Rheumatology, Graduate School of Medicine, The
University of Tokyo, Tokyo, Japan

Comprehensive Flow Cytometric Analysis of Immune Cell Subsets in PBMCs from Idiopathic
Inflammatory Myopathy Patients

100635 3-G-W39-12-P

Madoka Terashima

Center for iPS Cell Research and Application, Kyoto University, Kyoto, Japan

Establishment of a pluripotent cell model of Nakajo-Nishimura syndrome

100363 3-H-W40-1-O/P

Jing Wang

Institute of Enzyme Research, Tokushima University, Tokushima, Japan

Tracking the fate of neutrophils in sterile injury using photoactivation and intravital imaging

100390 3-H-W40-2-P

Shin Morisawa

Department of Immunology, Kitasato University Graduate School of Medical Sciences, Quantitative analysis of Neutrophil extracellular traps (NETs) in lupus prone mouse using novel
Sagamihara, Japan.
methods

100647 3-H-W40-3-P

Matsuba Shintaro

Department of Immunology, School of Medicine, Kanazawa Medical University,
Uchinada, JapanSLPI negatively regulates LPS-induced eosinophil activation via inhibition of Elk-1 phosphorylation

100021 3-H-W40-4-P

Kensuke Yanashima

Atopy (Allergy) Research Center, Juntendo University Graduate School of Medicine,Tokyo, Japan<strong>Synthetic host defense peptide IDR-1018 activates various functions of human mast
cells</strong>

100120 3-H-W40-5-P

Kyosuke Inui

Department of Immunology, Graduate School of Pharmaceutical Sciences, Hokkaido
University, Hokkaido, Japan

STAP-2 negatively controls Fc&epsilon;RI-mediated mast cell activation.

100122 3-H-W40-6-P

Kazumi Kasakura

Department of Biological Science and Technology, Tokyo University of Science, Tokyo,
The effect of commensal bacteria on anaphylactic reactionJapan

100225 3-H-W40-7-P

Nobuhiro Nakano

Atopy (Allergy) Research Center, Juntendo University Graduate School of Medicine,Tokyo, Japan

100247 3-H-W40-8-P

Izumi Fujigaki

Department of Biological Science and Technology, Tokyo University of Science, Tokyo,
Suppression of mast cell-mediated allergic responses by valerate, butyrate, and niacin via GPR109a.
Japan

100248 3-H-W40-9-P

Yuki Nakamura

Department of Immunology, Faculty of Medicine, University of Yamanashi, Japan

100276 3-H-W40-10-P

Azusa Kageyama

Department of Biological Science and Technology, Tokyo University of Science, Tokyo,
Physiological significance of IL-10 produced by mucosal type mast cells
Japan

100281 3-H-W40-11-P

Takahiro Arai

Department of Biological Science and Technology, Tokyo University of Science, Tokyo,
Transcriptional regulation of basophil-specific proteases
Japan

100284 3-H-W40-12-P

Megumi Iwasaki

Department of Biological Science and Technology, Tokyo University of Science, Tokyo, Generation of mutant mouse Fc&epsilon;RI&alpha;, which can be expressed asJapan&alpha;&gamma;<sub>2</sub> trimer and can bind to mouse IgE with high affinity

100360 3-H-W40-13-P

Shotaro Nakajima

Dept. Immunology, Univ. Yamanashi, Yamanashi, Japan

Resveratrol inhibits IL-33-mediated mast cell activation

100370 3-H-W40-14-O/P Wakabayashi Seiichiro

Dermatology, Chiba University, Chiba, Japan

Homeostasis of peripheral macrophages are controlled by mast cells <em>via</em> newly identified cKit<sup>+</sup>CD11b<sup>+</sup> tissue-resident macrophage progenitor cells

100434 3-H-W40-15-O/P Yuta Kogure

Division of Mucosal Immunology, Department of Microbiology and Immunology, The
Institute of Medical Science, The University of Tokyo, Tokyo, Japan

Mesenchymal-mediated skin-specific regulatory system for the control of tissue resident mast cells

100471 3-H-W40-16-P

Makiko Uchida

Department of Biological Science and Technology, Graduate School of Industrial
Science and Technology, Tokyo University of Science, Tokyo, Japan

Functional analysis of transcription factor Ehf.

100472 3-H-W40-17-P

Kazuki Saida

Laboratory of Molecular Biology and Immunology, Department of Biological Scienceand Technology, Faculty of Industrial Science and Technology, Tokyo University of
Science, 6-3-1 Niijuku, Katsushika-ku, Tokyo 125-8585, Japan.

Mucosal mast cell differentiation is regulated by cross-talk between Notch signaling and TGF-&beta;
signaling.

100515 3-H-W40-18-P

Kumi Izawa

Atopy (Allergy) Research Center, Juntendo University School of Medicine, Tokyo,
Japan<strong>Mast cell- and IgE-dependent anaphylaxis is regulated by paired receptors LMIR3 andLMIR7</strong>

100520 3-H-W40-19-P

Shino Uchida

Atopy (Allergy) Research Center, Juntendo University School of Medicine, Tokyo,
Japan<strong>A critical role of an inhibitory receptor LMIR3 in the pathogenesis of food allergy</strong>

Mast cells acquire intestinal antigen-presenting cell-like properties by Notch signaling

Regulation of plasma histamine levels by the mast cell clock and its modulation by stress100604 3-H-W40-20-O/P Shota Toyoshima

Allergy and Immunology Research Project Team, Center for Institutional Research andComparison of microRNA in human mast cell-derived exosomes in innate and acquired immunity
Medical Education, Nihon University School of Medicine, Tokyo, Japan

100616 3-H-W40-21-O/P Jun-ichi Kashiwakura

Department of Immunology, Graduate School of Pharmaceutical Sciences, Hokkaido
University, Hokkaido, Japan

STAP-2 is an adopter molecule to positively regulate basophil activation

100456 3-H-W40-22-O/P Tomoyuki Bando

Ono pharmaceutical co., ltd. Exploratory Research Laboratories, Osaka, JAPAN<strong>Differential usage of COX-1 and COX-2 in prostaglandin production by mast cells andbasophils</strong>

100428 3-H-W40-23-P

The Department of Immune Regulation, Tokyo Medical and Dental University, Tokyo,
Japan

Sugar modification of carrier protein confers ability on allergen to induce IgE- and basophil-mediatedallergic inflammation

100488 3-H-W40-24-O/P Takuya OHTA

Department of Immune Regulation, Tokyo Medical and Dental University Graduate
School, Tokyo, Japan

Skin-resident memory CD4<sup>+</sup> T cells play an essential role in acquired tick resistancethrough IL-3-mediated basophil recruitment

100546 3-H-W40-25-P

Yuya TABAKAWA

Department of Immune Regulation, Tokyo Medical and Dental University Graduate
School, Tokyo, Japan

Histamine plays a critical role in acquired protective immunity against tick infestation

100637 3-H-W40-26-P

Hidemitsu Tsutsui

National Center for Global Health and Medicine Research Institute, Tokyo, JapanThe basophil-specific protease mMCP-8 provokes an inflammatory response in the skin withmicrovascular hyperpermeability and leukocyte infiltration

100665 3-H-W40-27-O/P Kensuke Miyake

Department of Immune Regulation, Graduate School of Medical and Dental Sciences,
Tokyo Medical and Dental University (TMDU), Tokyo, Japan

Basophils exert antigen presentation via trogocytosis-mediated acquisition of peptide-MHC class II
complexes from dendritic cells (DCs)100433 3-H-W41-1-O/P

Takumi Itoh

Department of Therapy Development and Innovation for Immune disorders andCancers, Graduate School of Medicine, Juntendo University, Tokyo, Japan

IL-26 facilitates angiogenesis and skin inflammation via inducing FGF2 production in a murine model of
imiquimod-induced psoriasis

100349 3-H-W41-2-P

Zhang Baoluo

Laboratory of Pharmacotherapy of Life-Style Related Diseases, Tohoku University

Role of histamine in IL-17 expression in Imiquimod-induced psoriasis-like inflammation model

100399 3-H-W41-3-P

Shoichiro Miyatake

Department of Immunology, Graduate School of Environmental Health Sciences,
Azabu University, Kanagawa, Japan

Dermatitis developed in GATA3 mutant mice

100482 3-H-W41-4-O/P

Taro Watabe

Department of gastroenterology, Tokyo Medical and Dental University, Tokyo, Japan

Analysis of ileocecal immune response in an experimental colitis model using intra-vital imaging

100277 3-H-W41-5-P

Natsumi Kikuchi

Department of Biosciences, School of Science, Kitasato University, Kanagawa, JapanThe roles of ILC3 and &gamma;&delta; T cells in the development of colitis of the model-mice

100305 3-H-W41-6-P

Shigeki Sakai

Department of Medicine, Shiga University of Medical Science, Shiga, Japan

Bortezomib suppresses the development of experimental colitis by inhibiting the activation of NF&kappa;B100310 3-H-W41-7-P

Miki Matsui

Department of Pharmacology, Kyoto Pharmaceutical University, Kyoto, JapanThe role of Ca<sup>2+</sup>-activated K<sup>+</sup> channel K<sub>Ca</sub>3.1 in mesentericlymph node CD4<sup>+ </sup>T cells of chemically-induced murine inflammatory bowel diseasemodel

100215 3-H-W41-8-P

Taizo Mori

Department of Immune Regulation, The Research Center for Hepatitis and
Immunology, Research Institute, National Center for Global Health and Medicine

Lnk/Sh2b3 regulates adipose inflammation and glucose tolerance through group1-ILCs

100385 3-H-W41-9-O/P

Kota Nishihama

Mie University Graduated School of Medicine, Diabetes, Metabolism andEndocrinology, Tsu, Japan

Anti-diabetic effect of matrix metalloproteinase-2 and its correlation with protein S in diabetes

100401 3-H-W41-10-P

Taro Yasuma

Department of Immunology, Mie University Graduate School of Medicine

Protein S inhibits apoptosis of pancreatic &beta; cells by regulating BIRC3 expression and AKT
signaling

Toshihisa NAGAO

100415 3-H-W41-11-O/P Atsuro Takeshita

Diabetes, Metabolism and Endocrinology, Mie University Graduate School of Medicine,Protein S reduces the progression of diabetic nephropathy in miceTsu, Japan

100649 3-H-W41-12-P

Department of Immunology, Faculty of Pharmaceutical Sciences, Hokkaido University

The role of signal-transducing adaptor protein-1 in Concanavalin A-induced hepatitis

100330 3-H-W41-13-O/P Yosuke Kurashima

Division of Mucosal Immunology, Department of Microbiology and Immunology, The
Institute of Medical Science, The University of Tokyo, Tokyo, Japan<strong>Mesenchymal-myeloid cell interactions in renal microenvironment for pathological fibrogenic
machinery in kidney fibrosis</strong>

100638 3-H-W41-14-O/P Naoto Sasaki

Department of Medical Pharmaceutics, Kobe Pharmaceutical University, Kobe, Japan

Ultraviolet B exposure prevents atherosclerotic cardiovascular disease by regulating
immunoinflammatory responses

100492 3-H-W41-15-O/P Akira Taruya

Department of Cardiovascular Medicine, Wakayama Medical University, Wakayama,Japan

Decline of lysyl oxidase protein causes acute aortic dissection in Spi-B knockout mice

100437 3-H-W41-16-O/P Tomonori Kaifu

Department of Immunology, Tohoku Medical and Pharmaceutical University

DCIR negatively regulates osteoclastogenesis by binding to a novel endogenous ligand

Takeru Ihara

12 / 13

The 46th Annual Meeting of The Japanese Society for Immunology

Session Title

W42 T cell-2 : T cell signaling

W43

T cell-3 : T cell function

Date

Dec. 14(Thu.), 2017

Dec. 14(Thu.), 2017Time

Odd Number /16:00-17:00
Even Number /17:00-18:00

Odd Number /16:00-17:00
Even Number /17:00-18:00

Submission ID

Program for Poster

Program No.

1st Author

Affiliation

Abstract Title

100561 3-I-W42-1-P

Manabu Inobe

Institute of Medical, Pharmaceutical and Health Sciences, Kanazawa University,
Kanazawa, Japan

100194 3-I-W42-2-P

Saitoh Kodai

Department of Immunology, Faculty of Pharmaceutical Sciences, Hokkaido University,
A role of STAP-2 in T cell activation and T cell-mediated immune responses
Hokkaido, Japan

100518 3-I-W42-3-P

Matsui Yukihide

Department of molecular immunology, the faculty of medicine, Toho University, Tokyo,
TCR-stimulation recruits CBP from nucleus to the cytoplasm and affects the protein phosphorylation
Japan

100609 3-I-W42-4-O/P

Ryunosuke Muro

Graduate School of Medicine and Faculty of Medicine, The University of Tokyo, Japan

Control of proinflammatory &gamma;&delta;T cell development by linage-specific TCR signaling
pathway

100015 3-I-W42-5-O/P

Honglian Tong

Division of Molecular and Cellular Immunoscience, Department of Biomolecular
Sciences, Faculty of Medicine, Saga University, Saga, Japan

Apaf1 plays a negative regulatory role in T cell responses by suppressing activation of antigenstimulated T cells

100391 3-I-W42-6-O/P

Takayuki Imanishi

RIKEN Center for Integrative Medical Sciences (IMS) Laboratory for Cell Signaling,
Yokohama, Japan

TCR-signals control STING-mediated type 1 IFN responses in T cells

100449 3-I-W42-7-P

OGAWA Shuhei

Division of Immunobiology, Research Institute for Biomedical Sciences, Tokyo
University of Science

The regulation of CD28 tyrosine phosphorylation and the function of CD28-mediated costimulation.

100049 3-I-W42-8-P

Kaoru Toshima

Division of Glycopathology, Institute of Molecular Biomembrane and Glycobiology,
Tohoku Medical and Pharmaceutical University, Miyagi, Japan

Sphingomyelin is involved in TCR-induced apoptosis in thymocyte development

100178 3-I-W42-9-O/P

Eun Jeong Park

Mie University Graduate School of Medicine, Mie, Japan&beta;7 integrin-mediated homing of exosomes to the gut

100594 3-I-W42-10-O/P

Yuji Kamioka

Department of Molecular Genetics, Institute of Biomedical Science, Kansai Medical
University, Osaka, Japan

Roles of Rap1 and Kindlin-3 in lymphocyte homing to peripheral lymph nodes

100417 3-I-W42-11-O/P

Tsuyoshi Sato

Department of Biosciences, School of Science, Kitasato University, kanagawa, JapanT cell specific Rap1-deficient mice develop spontaneous colitis

100461 3-I-W42-12-O/P

Naoyuki Kondo

Kansai medical university, Hirakata, Osaka, Japan

NDR1 acts as a molecular hub for the organization of immunological synapse

100439 3-I-W42-13-P

Kenta Iwasaki

Department of Kidney Disease and Transplant Immunology, Aichi Medical University
School of Medicine, Aichi, Japan

Differential response of allo-reactive CD4 T-cells against HLA class II expressed on endothelial cells in
the presence of HLA and ABO antibody.

100478 3-I-W42-14-O/P

Akiko Hashimoto-Tane

RIKEN Center for Integrative Medical Science, Yokohama, Japan

Molecular assembly and function of PTPN22 in T cell receptor signaling

100652 3-I-W42-15-P

Hiroaki Machiyama

Deparment of Immunology, Tokyo Medical University, Tokyo, JapanTCR signaling introduces endocytic machineries at the microclusters

100521 3-I-W42-16-P

Koji Eshima

Kitasato University School of Medicine

Implication of T-bet, the master regulator of Th1 cells, in the cytotoxicity of murine CD4<sup>+</sup> T
cells

100657 3-I-W42-17-P

Hiroki Yatsu

Division of Molecular Pathology, Research Institute for Biomedical Science, Tokyo
University of Science, Noda, Japan

Regulation Mechanism of Differentiation in Type 1 Helper T cell (T<sub>H</sub>1) and Follicular
Helper T cell (T<sub>FH</sub>) Specific for Influenza A Virus

100187 3-I-W43-1-O/P

Jisu Ma

Department of Immunoparasitology, Research Institute for Microbial Diseases, Osaka
University, Osaka, Japan<strong>PLC&beta; plays an important role in CD8 T cell-mediated host defense against<em>Toxoplasma gondii</em></strong>

100556 3-I-W43-2-P

Yuki TABATA

Research Institute for Biomedical Sciences, Tokyo University of Science, Chiba, Japan<strong>IL-2 production is negatively regulated by free fatty acid receptor 2 (Ffar2) mediatedsignaling.</strong>

100557 3-I-W43-3-P

Masanobu Kimura

Department of Microbiology and Immunology, Tohoku University Graduate School of
Medicine, Sendai, Japan<strong>TRAF2 and TRAF5 binding to the signal transducing receptor gp130 inhibit JAK1 activation in
the IL-6-receptor signaling complex</strong>

100211 3-I-W43-4-P

Tomohiro Masuda

名古屋市昭和区

Growth factor Midkine promotes NFAT activation and Th1 differentiation in lupus Nephritis

100059 3-I-W43-5-O/P

Akihiro Shimba

Institute for Frontier Life and Medical Sciences, Kyoto University, Kyoto, Japan

Glucocorticoids drive diurnal changes in distibution and response of T cells via IL-7 receptor expression

100074 3-I-W43-6-P

Guangwei Cui

Laboratory of Immune Regulation, Institute for Frontier Life and Medical Sciences,
Kyoto University, Kyoto, Japan

Competition between STAT5 and PI3K of the IL-7R modulates T cell and type 2 ILC development in
vivo

100505 3-I-W43-7-P

Shizue Tani-ichi

Institute for Frontier Life and Medical Sciences, Kyoto University, Kyoto, Japan

Exploring the signals upregulating IL-7R&alpha; expression via NF&kappa;B activation in T cells

100262 3-I-W43-8-O/P

Mohammad A SAYEM

Division of Cellular Signaling, Advanced Institute of Medical Research, Keio University <strong>IL-8 has a negative role on tumor infiltrating CD8<sup>+</sup> T cells in various
School of Medicine, Tokyo, Japancancers</strong>

100051 3-I-W43-9-P

Ryoyo Ikebuchi

Laboratory of Immunology, Faculty of Pharmacy, Osaka Ohtani University,
Tondabayashi, Osaka, Japan

Single-cell gene and protein expression analysis revealed functional and migratory heterogeneity inregulatory T cells of inflamed skin100615 3-I-W43-10-P

Yoichi Maekawa

Department of Parasitology and Infectious Diseases, Gifu University Graduate Schoolof Medicine, Gifu, Japan

The immune responses of CD4<sup>+</sup> T cells are affected by hypergravity

100563 3-I-W43-11-O/P

Akio Ohta

Department of Molecular Medicine, Foundation for Biomedical Research andInnovation, Kobe, Japan

Transient hypoxia persistently inhibits T cell activation

100152 3-I-W43-12-P

Yumiko Kanno

Department of Immunology, Dokkyo Medical University School of Medicine, Mibu,
Shimotsuga, Tochigi, JapanHIF-1&alpha; plays a key role in regulation of homeostatic energy metabolism in cytotoxic T
lymphocytes.

100022 3-I-W43-13-O/P

Junpei Suzuki

Department of Hematology, Clinical Immunology and Infectious Diseases, Ehime
University Graduate School of Medicine, Ehime, Japan<strong>The tumor suppressor menin epigenetically regulates CD8 T cell senescence via themodulation of glutamine metabolism</strong>

100582 3-I-W43-14-O/P

Hisako Akatsuka

Department of Host Defense Mechanism, Tokai University School. of Medicine,
Kanagawa JapanAMBRA1 is involved in T cell receptor-mediated metabolic reprogramming through ATG7-independent
pathway

100140 3-I-W43-15-O/P

Michio Miyajima

Laboratory for Mucosal Immunity, Center for Integrative Medical Sciences, RIKEN
Yokohama Institute, Yokohama, Japan

Systemic metabolic shift induced by PD-1 deficiency perturbs brain monoamines and emotional
behaviour

100112 3-I-W43-16-P

Ruka Setoguchi

RIKEN Center for Integrative Medical Sciences, Kanagawa, Japan<strong>Impairment of memory CD8 T cell maintenance in MHC class II deficient mice is caused byinflammation not by CD4 T cell deficiency</strong>

100414 3-I-W43-17-O/P

Harumichi Iahigame

Laboratory for Tissue Dynamics, RIKEN Center for Integrative Medical Sciences,
Kanagawa, Japan<strong>Developmental plasticity of KLRG1<sup>+</sup> effector CD8<sup>+</sup> T cells
promotes protective immunity</strong>

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CD8<sup>+</sup> T cells are less dependent on Erk to proliferate compared with CD4<sup>+</sup>T cells