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Safety Data Sheet
1. Chemical product and company identification
Product name: 2-BUTANONE

Company information
Name of manufacturer
Address
Name of section
Telephone number
Facsimile number
Mail address
Reference No： KANTO CHEMICAL CO., INC.
： 2-1, Nihonbashi, Muromachi 2-Chome, Chuo-Ku, Tokyo, 103-0022, Japan： Electronic materials division technical department： +81-3-6214-1080： +81-3-3241-1043： el-info@kanto.co.jp: GE00002 1.4

Recommended uses andrestrictions: Electronic chemicals

2. Hazards identification
GHS classification
Physical hazards

Flammable liquids

Category 2

Health hazards

Acute toxicity(inhalation:vapors)

Category 4

Skin corrosion/irritation

Category 2

Serious eye damage/eyeirritation

Category 2ASpecific target organ toxicity(single exposure)

Category 2 (kidney)

Specific target organ toxicity(single exposure)

Category 3 (narcosis)

Specific target organ toxicity(single exposure)

Category 3 (respiratory tract irritation.)

Specific target organ toxicity(repeated exposure)

Category 1 (nervous system)

Hazardpictograms

Signal word:

DangerHazard statements:

Highly flammable liquid and vapor
Causes skin irritation
Causes serious eye irritation
Harmful if inhaled
May cause respiratory irritation
May cause drowsiness or dizziness
May cause damage to organs (kidney)
Causes damage to organs (nervous system) through prolonged orrepeated exposure

Precautionary statements

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Prevention:

Keep away from heat, hot surfaces, sparks, open flames and otherignition sources. No smoking.
Keep container tightly closed.
Ground and bond container and receiving equipment.
Use explosion-proof electrical/ventilating/lighting equipment.
Use only non-sparking tools.
Take action to prevent static discharges.
Do not breathe mist/vapors.
Wash hands, forearms and face thoroughly after handling.
Do not eat, drink or smoke when using this product.
Use only outdoors or in a well-ventilated area.
Wear protective gloves/protective clothing/eye protection/faceprotection.

Response:IF ON SKIN: Wash with plenty of water.
IF ON SKIN (or hair): Take off immediately all contaminatedclothing. Rinse skin with water .
IF INHALED: Remove person to fresh air and keep comfortable forbreathing.
IF IN EYES: Rinse cautiously with water for several minutes.
Remove contact lenses, if present and easy to do. Continue
rinsing.
IF exposed or concerned: Call a POISON CENTER or doctor.
Call a POISON CENTER or doctor if you feel unwell.
Get medical advice/attention if you feel unwell.
If skin irritation occurs: Get medical advice/attention.
If eye irritation persists: Get medical advice/attention.
Take off contaminated clothing and wash it before reuse.

Storage:

Store in a well-ventilated place. Keep container tightly closed.
Store in a well-ventilated place. Keep cool.
Store locked up.

Disposal:

Dispose of contents/container to hazardous or special waste
collection point, in accordance with local, regional, national
and/or international regulation.

3. Composition/information on ingredients
Distinction of substance ormixture:

Substance

Synonyms:

MEK, Ethyl methyl ketone, Methyl ethyl ketone

Chemical name2-Butanone

Concentration (%)
min. 99.9

FormulaC2H5COCH3

TSCA
ListedEC-No.
201-159-0

CAS RN78-93-3

4. First aid measures
First aid measures
First-aid measures afterinhalation:

Remove the victim to fresh air, and make him blow his nose andgargle. If necessary, get medical treatment.

First-aid measures after skincontact:

Wash the affected areas under running water.

First-aid measures after eye
contact:

Wash the affected areas under running water for at least 15
minutes. Get medical treatment.

First-aid measures after:

The chemical is volatile. Do not induce vomiting because it
increases the risk of aspiration into the lungs. Get medical

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ingestion
Personal Protection in FirstAid and Measuresattention immediately. If necessary, rinse mouth with water.
:

Rescuers should wear proper protective equipment like rubber
gloves, goggles.

:

Overexposure may cause anesthetic action, headache, dizziness,tunnel vision, nausea, or unconsciousness.

Suitable extinguishing media:

Dry chemical, CO2, dry sand, or alcohol-resistant foam

Unsuitable extinguishing media:

Water spray, Foam extinguisher

Firefighting instructions:Move containers from fire area if it can be done without risk, if
not possible, apply water from a safe distance to cool andprotect surrounding area.

Most Important Symptoms/Effects
Symptoms/effects

5. Fire fighting measures

Fight fire from windward.
Dry chemical powder, carbon dioxide or dry sand should be used
for small fires. Alcohol-resistant foam extinguisher is effective
for a large scale fire.
Personal protection (Emergencyresponse):

Firefighters should wear protective equipment.

6. Accidental release measures
Personal Precautions, Protective Equipment and Emergency Procedures
General measures:

Wear proper protective equipment and avoid contact with skin andinhalation of vapor. Conduct operations from upwind and evacuate
people downwind. Remove all sources of ignition. Keep away
personnel except for authorized ones from spillage area by
stretching ropes.

:

Attention should be given to avoid discharge of spilled productinto rivers and resulting environmental damage. When diluting
spill with large amounts of water, discharge of untreatedwastewater into the environment must be avoided.

Environmental precautions
Environmental precautions

Methods and Equipment for Containment and Cleaning up
For containment:

Absorb spill with inert material （e.g, diatomaceous earth,sand） and flush spillage area with copious amounts of water.
Remove nearby sources of ignition and prepare extinguishingmedia.

7. Handling and storage
Handling
Technical measures:

Wear proper protective equipment to avoid contact with skin orinhalation of vapor. Fire is strictly prohibited.

Precautions for safe handling:

Use with an enclosed system or a local exhaust ventilation. Usein well-ventilated areas.

Storage conditions:

Store in a dark, cool place and tightly closed.

Material used inpackaging/containers:

Glass, stainless steel.

Storage

Do not use vinyl chloride resin, acrylic resin, polystyrene etc.

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8. Exposure controls / Personal protection equipment
ACGIH TWA

200 ppm

ACGIH STEL

300 ppm

Appropriate engineering
controls
Protective equipment: Use with an enclosed system or a local exhaust ventilation.

Respiratory protection: If necessary, wear gas mask for organic solvents or airline
respirator.

Hand protection: Organic solvents resistant gloves

Eye protection: Safety goggles

Skin and body protection: Protective clothing, protective boots

9. Physical and chemical properties
Physical state: LiquidColor: Colorless.

Odor: Acetone like odor

pH

: No data available

Melting point: -86.7 °C

Freezing point: No data available

Boiling point: 79.64 °C

Flash point: -7.2 °C

Auto-ignition temperature: 516 °C

Decomposition temperature: No data available

Flammability: Flammable

Vapor pressure: 105 hPa (20℃)

Relative density: No data available

Density: 0.80 g/cm³ (20℃)

Relative gas density: 2.5Solubility: Organic solvents: Miscible with many kinds of organic solvents.
Water: 21.1 % (20℃): 0.29Partition coefficient noctanol/water (log Pow)
Explosive limits (vol %): 1.18 – 11.5 vol %Viscosity, kinematic:: 0.5 mm²/s (25℃)

Particle characteristics: No data available

10. Stability and reactivity
Reactivity: May react with oxidizing substances.

Chemical stability: Stable under normal conditions.

Possibility of hazardousreactions: Stable under normal conditions of use.

Conditions to avoid: Light, heat.

Incompatible materials: Oxidizing substances.

Hazardous decomposition
products: Carbon monoxide.

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11. Toxicological information
Acute toxicity (oral)
Acute toxicity (dermal)
Acute toxicity (inhalation): No classification
rat LD50=2737mg/kg: No classification
rabbit LD50>5000mg/kg: No classification (gas)Harmful if inhaledClassification not possible (dust, mist): rat LC50=11700ppm/4h

Acute toxicity (vapor) Description
Skin corrosion/irritation:Serious eye damage/irritation:

Respiratory sensitization
Skin sensitization
Germ cell mutagenicity:::

Carcinogenicity:

Reproductive toxicity:

STOT-single exposure:

Causes skin irritation
Based on the description that mild to moderate irritation wasobserved in the skin irritation test on rabbits, it was classified
into category 2.
Causes serious eye irritation
Result of this material was applied to the eye of the rabbit, there
is a report that severe irritation was observed, and bleeding ofcorneal disorder and sclera, edema of the eyelids, chemical burns
were observed. In addition, the average value of the mark in 24hours, was corneal cloudings was 2.5 and the conjunctival redness
was 2 in the eye irritation examination using a rabbit, but it had
recovered mostly within seven days, so, it was classified into
category 2A.
Classification not possible
Classification not possible
No classification
As for in vivo tests, there are negative data on micronucleus assay
in mouse bone marrow cells.
No classification
Since it was classified as I (inadequate) by EPA.
Classification not possible
There are descriptions that fetal malformations were observed interatogenicity studies of inhalation exposures in rats. In aretest, however, malformations are not observed, although delayed
ossification and mutations were observed. Furthermore, malformation
is not observed, although lower weight levels of offsprings andmutations were also observed in teratogenicity studies ofinhalation exposure to mice. Therefore, all were judged to beminimum influence. However, since there is no report of the test
related to fertility, it was not possible to classify.
May cause damage to organs (kidney)
May cause drowsiness or dizziness
May cause respiratory irritation
In humans, in the inhalation exposure, there is the report thatcauses headache, dizziness, nausea, vomiting, ataxia, eye blurredvision, lightheadedness, hyperventilation, dizziness, lethargy,
central nervous system depressant action, metabolic acidosis, lossof consciousnes. In the oral administration, there is the report ofloss of consciousness. In experimental animals, anesthetic action,
mild renal tubular necrosis of the kidneys were recognized in theoral administration 1,080 mg/kg in rats. Effects on the kidneys of
the rats was observed at doses ranging from category 2. This
material is considered to have effects on the kidney, andrespiratory tract irritation, the anesthetic action. From theabove, it was classified into category 2((kidney), category 3(respiratory tract irritation, narcosis).

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STOT-repeated exposure:

Causes damage to organs (nervous system) through prolonged orrepeated exposure
There is the description that numbness of the hands and arms wereobserved in human occupational exposure cases. And since there isthe description that disorders of central nervous system aresuggested in occupational exposure example, target organ isconsidered nervous system, it was classified into category1(nervous system).

Aspiration hazard:

Classification not possible
This substance is a ketone composed of no more than 13 carbon
atoms, and its kinematic viscosity was 0.50 mm2/s. Since itcorresponds to category 2, it was classified as "Classification notpossible" according to the Classification Guidance for the Japanese
Government.

12. Ecological information
Ecotoxicity
Aquatic acute
Aquatic chronic: No classification
Oryzias latipes LC50>100mg/L/96h: No classification
Pseudokirchneriella subcapitata NOEC=93mg/L/72h

Persistence and degradability
Readily biodegradable
BOD : 89%
Bioaccumulative potential
Low bioconcentrationlog Pow : 0.29
Mobility in soilHigh mobility
Koc : 29.5-33.9
Hazardous to the ozone layer
Ozone: Classification not possible

13. Disposal considerations
Ecological waste information: Burn in a chemical incinerator equipped with an afterburnerand a scrubber. Or entrust approved waste disposal companies
with the disposal.

Contaminated container andpackaging: In case of disposal of empty bottles, dispose bottles after
removing the content thoroughly.

14. Transport information
International Regulations
Transport by sea(IMDG)
UN-No. (IMDG)
Proper Shipping Name (IMDG)
Packing group (IMDG)

:::

1193
ETHYL METHYL KETONE (METHYL ETHYL KETONE)
II

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Transport hazard class(es)(IMDG)Air transport(IATA)
UN-No. (IATA)
Proper Shipping Name (IATA)
Packing group (IATA)
Transport hazard class(es)(IATA):3::::

1193
Ethyl methyl ketoneII3Marine pollutant: Not applicable
Transport in bulk according to Annex II of MARPOL 73/78 and the IBC Code
Pollutant category:ZMFAG-No:
127

15. Regulatory information
Regulatory information with regard to this substance in your country or region should be examined byyour own responsibility.

16. Other information
Data sources: Dictionary of Organic Compounds, The society of Synthetic
Organic Chemistry, Kodansha Ltd.（1985）.
Solvents Handbook, T, Asahara el, Kodansha Scientific Ltd.
（1976）.
Dangerous Properties of Industrial Materials,6th ed.
N.I.Sax Van Nostrand Reinhold Company（1984）.
Handbook of 17322 Chemical Products, The Chemical Daily Co.
（2022）.
NITE Chemical Risk Information Platform (NITE-CHRIP), National
Institute of Technology and Evaluation.

The information contained herein is based on several references and the present state of ourknowledge. However the SDS does not always cover all information about the product, handle theproduct carefully.The information is intended to ordinary usage, in case of particular handlings,
conduct appropriate safety measurements.The information herein is only provision of information, andit does not represent a guarantee the properties of the product.The Safety Data Sheet(SDS) is
prepared based on JIS Z7253.