Kyowa Hakko Bio Announces a Change to the Representative Director
Tokyo, Japan — January 29, 2018: Kyowa Hakko Bio Co., Ltd. (President & CEO: ChikakuniKotani) announced today that it resolved the following change to the Representative Director at theBoard of Directors Meeting held on January 26, 2018.
This change will be approved in the 10th General Meeting of Shareholders scheduled to be held onMarch 20, 2018 and then formally decided at the Board of Directors Meeting held thereafter.

1．Reason for the change
The company has been working to expand revenue and restructure the business in line with thereorganization and expansion of the production sites set forth in the current Mid-term Business
Plan. Presently the major capital investments have leveled off, and the preparation of afoundation for expanding revenue has been completed to a certain extent. In order to achieve
further growth, along with pursuing increased profitability of existing products, accelerating thedevelopment of new products and businesses utilizing the company’s unique technologies
remains as an issue. In addition, creating synergies within the Kirin Group will also be one of thekeys to further growth. Given this business environment, Takeshi Minakata, who has abundant
experience at domestic production sites and overseas businesses in the Kirin Group, has been
selected to be the President & CEO of the company, and under his leadership, the company aims
to further develop the business.
2．New Representative Director candidate
Planned appointment date: Day of the General Meeting of Shareholders (scheduled for March20, 2018)<Name><New position><Current position>

Takeshi Minakata

President & CEO

Director and President of Myanmar
Brewery LimitedandSenior Executive Officer of Kirin
Holdings Company, Limited

3．Retiring Representative Director
Planned retirement date: Day of the General Meeting of Shareholders (scheduled for March 20,2018)<Name><New position><Current position>
Chikakuni Kotani

President & CEO※ President & CEO Chikakuni Kotani will be appointed Executive Officer and Director of theOverseas Business Department at Kyowa Hakko Kirin Co., Ltd. in the General Meeting ofShareholders scheduled in the end of March 2018, and he will be appointed as the President ofKyowa Hakko Kirin (Singapore) Pte. Ltd. on April 1, since when he will be responsible formanaging the business in Asia and Oceania.

4．Curriculum Vitae
President and CEO candidate,Takeshi Minakata
Date of birth: December 31, 1961
Education: Graduated from the University of Tokyo in 1984
Received his BA of Agricultural chemistry.
Business experience
Apr. 1984

Joined Kirin Brewery Co., Ltd. (presently Kirin Holdings Company, Limited)

Mar. 2007

Deputy General Manager, Kirin Toride BreweryMar. 2009

Deputy General Manager, Production Dept., Kirin Brewery Co., Ltd

Oct. 2010

Kirin Liaison Technical Director, Lion Nathan National Foods (presently LION :Australia)

Mar. 2012

General Manager, Corporate Planning Dept., Kirin Brewery Co., Ltd.

Jan. 2013Executive officer, General Manager, Management Planning Department, Kirin
Co., Ltd and Kirin Brewery Co., Ltd.

Mar. 2015

Senior Executive officer, Director Corporate Strategy, Kirin Holdings Co., Ltd
Senior Executive officer, General Manager, Management Planning Department,
Kirin Co., Ltd

Mar. 2016

Director and President of Myanmar Brewery Limited
Senior Executive officer, General Manager, Management Planning Department,
Kirin Holdings Co., Ltd