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⺰ᢥ࡮ቇળ╬߳ߩ⊒⴫㧔㧝㧕⺰ᢥ╬⊒⴫৻ⷩ
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㒐㖸ოߩㆤ㖸ᕈ⢻ߦ෸߷ߔ㖸Ḯᜰะᕈ ᧻ᧄḮ↢㧘⮮ේᕶม㧖⿥㖸ᵄ࠹ࠢࡁ㧘Vol㧘ߩᓇ㗀No㧘- 

Uptake㧖 ਻Ꮊᄢቇ
of

ᛞ㍳ឝタ㗁
P 

p o l y c h l o r i n a t e d Takahiko Matsueda Yoichi Kurokawa ⑔ጟ⋵଻ஜⅣႺ⎇ⓥᚲᐕႎ P 

dibenzo-p-dioxins and furans in plant Hironori Hirakawa Ryuichi Suda and ╙ภ㧘-㧘
leavesA

Takao Iida

Longitudinal

AssociationofAnalysisSerum

the Shoji Tokunaga 㧖 and Kyoichiro Kataoka⑔ጟකቇ㔀⹹

and 㧖 ਻Ꮊᄢቇ  㧘-㧘

on

LipidsP 

Lipoproteins Concentrations with Blood
Polychlorinated Biphenyls level in Chronic"Yusho" Paitients
Ვ⩶ലജ⹜㛎↪ᬌᩏ᧚ᢱߣߒߡឭ಴ߐ ၳᎹ๺⟤ᣣᧄ㒐⩶㒐㤻ቇળ㔀⹹㧘ࠇߚᶖᲥ⮎ߦᷙ౉ߒߡ޿ߚ࠮࡜࠴ࠕ⩶Vol㧘- 

Vibrio cholerae Oᗵᨴ੐଀㧙⑔ጟ⋵ၳᎹ๺⟤㧘᧛਄శ৻㧘㐳㊁⧷ବ㧘ựፒ ∛ේᓸ↢‛ᬌ಴ᖱႎ㧘P శብ㧘⍹㤥㕏ዏ㧘⨹Ꮉ⧷ੑ 㧖  㧘ᷰㆺᴦ VolNo  
㓶㧖㧘ㄭ⮮ᱜᴦ㧖㧘᫪↰❥㧖㧘ේ৻⟤㧖㧘ᳯፒᵏਯ㧖㧖 ࿖┙ᗵᨴ∝⎇ⓥᚲ㧖 ਭ⇐☨⥃ᐥᬌᩏ࠮ࡦ࠲࡯㧖 ߃ߐ߈ዊఽ⑼࡮ౝ⑼ක㒮Structure activity relationship between Hiroshi Tokiwa 㧖   Nobuyuki Sera
Salmonella-mutagenicity

a n d Kiyoshi Fukuhara

nitro-orientation of nitroazaphenanthrenes

P  Hideo Utsumi

㧖



㧖

Shigeki Sasaki 㧖 and Naoki Miyata 㧖C h e m i c o - B i o l o g i c a l P 
Interactions Vol
- 

㧖 Kyushu Women's University㧖 National Institure of Health Sciences㧖 Kyushu University㧖 Nagoya City University
GC/MS ߦࠃࠆㄘ૞‛ਛᱷ⇐ㄘ⮎ߩ৻ᢧ ⧃Ⴆ↱♿㧘ਛᎹ␞ሶ⑔ጟ⋵଻ஜⅣႺ⎇ⓥᚲᐕႎ P 

ಽᨆᴺߩᬌ⸛

╙ภ㧘- 

ᴤ∝ᖚ⠪ⴊਛ࠳ࠗࠝࠠࠪࡦ㘃࡟ࡌ࡞ߩ 㘵↰㓉㓶㧘ᚭ㜞ዅ 㧖  㧘ᐔᎹඳ઄㧘㘧⍹ ⑔ጟකቇ㔀⹹ㅊ〔⺞ᩏ㧔ᐕ㧕P ๺ᄢ㧘᧻ᨑ㓉ᒾ㧘ၳዞ⧷㧘ਛᎹ␞ሶ㧘   㧘- 
ฎᳯჇ㓉㧖㧖 ᣣᧄ㘩ຠⴡ↢දળ㧘㧖 ਻Ꮊᄢቇⴊਛ PCB ࡄ࠲࡯ࡦ್ቯߦ߅ߌࠆᓥ᧪ᴺ ਛᎹ␞ሶ㧘⧃Ⴆ↱♿㧘ၳዞ⧷㧘ᐔᎹඳ ⑔ጟකቇ㔀⹹ߣ⇣ᕈ૕೎ಽᨆᴺߩห╬ᕈߦߟ޿ߡ

઄㧘㘧⍹๺ᄢ㧘㘵↰㓉㓶P   㧘- 
Vol

Measurement of blood dioxin in human Takao iida and Takashi Todaka 㧖Industrial Healthblood : Improvement of analytical Method 㧖 Japan Food Hygiene Association

No - 

-  -

P 

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New protocol of Dioxins analysis in Takashi Todaka 㧖㧘Hironori Hirakawa㧘 ⑔ጟකቇ㔀⹹
human blood

ᛞ㍳ឝタ㗁
P 

  㧘- 

Kazuhiro Tobiishi and Takao iida
㧖 Japan Food Hygiene Association

Frequency of SCEs in Japanese Infants Junya Nagayama 㧖㧘Mayumi Nagayama ⑔ጟකቇ㔀⹹P 

㧘Reiko Nakagawa㧘Hironori Hirakawa㧘   㧘- 

Lactatioally Exposed to Organochlonone

㧖

Pesticides

Takahiro

Matsueda

Takao

Iida

and

Jun'ichiro Fukushige 㧖㧖 Kyushu University㧖 Fukuoka Children's HospitalSO 㧘 NOx ࠍ㒰෰ߢ߈ࠆᣂߒ޿㜞ᵴᕈ ਅේቁ┨

‫ޟ‬࿑⸃

὇⚛❫⛽

ߩߔߴߡ‫ޠ‬㧙ⅣႺᣂ᧚ᢱ⎇ࠛࠦࡑ࠹ࠖ࡝ࠕ࡞ P ⓥળ✬㧙㧘Ꮏᬺ⺞ᩏળ⑔ጟ⋵ߦ߅ߌࠆቶౝൻቇ‛⾰ߩታᘒ⺞ ജኼ㓶㧘ᩉᎹᱜ↵㧘ự᧛⎇๋㧘ᄢ⍹⥝ ⑔ጟ⋵଻ஜⅣႺ⎇ⓥᚲᐕႎ P ᩏᒄ㧘ጤᧄ⋿ੑ㧘ਛ᧛෶ༀ╙ภ㧘- 
Hiroko Tsukatani Yoshito TanakaNobuyuki Sera Nobuhiro Shimizu
Shigeji Kitamori and Naohide Inoue 㧖㧖 Kyushu University

The Journal of Toxicological P 
Sciences Vol No
- 

Validity of mutagenic activity as an Hiroko Tsukatani Yoshito Tanakaindicator of river water pollution
Nobuyuki Sera Nobuhiro Shimizu
Shigeji Kitamori Naohide Inoue 㧖㧖 Kyushu University

Environmental Health and P 
Preventive MedicineVolNo - 

ඳᄙḧߦ߅ߌࠆࡎ࠻࠻ࠡࠬࠟࠗ߇⽺㉄ ᾢ⼱ඳผ㧘ጊፒᗅ⟵㧖㧘ᷰㄝ੫৻㧖㧘

ⅣႺᎿቇ⎇ⓥ⺰ᢥ㓸㧘⚛᳓႙ߦਈ߃ࠆᓇ㗀

Vol- 

Mutagenic activity in roadside soils⮮↰ஜ৻㧖㧖 ⑔ጟᄢቇP 㧖 ਻ᎺⅣႺ▤ℂදળ

Ꮏ႐ឃ᳓ಣℂᣉ⸳ߦ㑐ߔࠆᛛⴚ⋧⺣੐ ᾢ⼱ඳผ㧘ᔒ᳓ାᒄ㧘᳗ᷗ⟵ቁ㧘⑔ጟ⋵଻ஜⅣႺ⎇ⓥᚲᐕႎ P ଀ 㧙๧ཬ⵾ㅧ੐ᬺ႐ߩᵴᕈᳪᵆߩ▤ℂ ᧻የብ㧘ਛ᧛෶ༀ㧘⧯᧻⟤⍮ሶ㧖╙ภ- 

ߣో࡝ࡦߩ㑐ଥ㧙㧖 ጊ㐷଻ஜ⑔␩ⅣႺ੐ോᚲ

Seasonal variation of Be deposition in Yukinori Narazaki Kazunobu Fujitaka 㧖 Journal of Radioanalytical P 
Japan
Shuichi Igarashi 㧖Yoichi Ishikawa 㧖 and Nuclear Chemistry
Naoto Fujinami 㧖- 
㧖 National Institute of Radiological Sciences㧖 Fukui Prefectural Environmental
Radiation Monitoring Center㧖 Environmental Radioactivity ResearchInstitute of Miyagi
㧖 Kyoto Prefectural Instituteof Hygienic
and Environmental Sciences⑔ጟ⋵ߦ߅ߌࠆSr ෸߮Cs ߩỚᐲಽᬰፒᐘ▸㧘↰਄྾㇢

Ꮣߣផ⒖㧔㨪ᐕ㧕

଻ஜ‛ℂ㧘㧘-㧘-  -

P 

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㒠ਅ‛ਛߩ᡼኿⢻᷹ቯߦ߅ߌࠆᄢ㒽⿠ ⍹Ꮉ㓁৻㧖ᧁ┙ඳ㧖દ⮮▵↵㧖૒‫ ᧁޘ‬ች ၔ ⋵ ේ ሶ ജ ࠮ ࡦ ࠲ ࡯ ᐕ P Ḯࠛࠕࡠ࠱࡞ߩᓇ㗀㧔╙㧞ႎ㧕ବⴕ㧖ᬰፒᐘ▸↰਄྾㇢㋈ᧁ೑ቁ㧖ႎ㧘╙Ꮞ - 㧖 ችၔ⋵ේሶജ࠮ࡦ࠲࡯㧘㧖 ጊᒻᄢቇBio-kinetics

of

radon

ingestedfrom Tetsuo

drinking water

Ishikawa 㧖Yukinori Narazaki R a d i a t i o n

Yumi Yasuoka㧖Shinji Tokonami

P r o t e c t i o n P  Dosimetry㧘㧘 -㧘

㧖



Yuji Yamada 㧖㧖 National Institute of Radiological Sciences㧖 Kobe Pharmaceutical University࿾ਅ᳓ਛ࡜࠼ࡦỚᐲ᷹ቯⵝ⟎ߩᲧセ⍹Ꮉᔀᄦ 㧖቟ጟ↱⟤ 㧖ᬰፒᐘ▸ᐥᰴ Radioisotopes㧘㧘-㧘 P 㧙ᶧ૕ࠪࡦ࠴࡟࡯࡚ࠪࡦࠞ࠙ࡦ࠲㧘IM ⋿ม㧖⍹੗ᔘ㧖㗇↰ඳᢥ㧖ጊ↰⵨ม㧖 
ᴰല⸘㔚㔌▫࡜࠼ࡦࡕ࠾࠲ߢᓧࠄࠇ 㧖 ᡼኿✢කቇ✚ว⎇ⓥᚲߚ⚿ᨐ㧙㧖 ␹ᚭ⮎⑼ᄢቇ
㧖 ጊ᪸ᄢቇ㧖 㚅Ꮉᄢቇ
㔚⸃ᴺߦࠃࠆ࿾ਅ᳓ਛߩ⎣㉄ᕈ⓸⚛ߩ᧻የብ㧘╣የᢕሶ㧘᳗ᷗ⟵ቁ㧘⍹ᯅⲢ ⑔ጟ⋵଻ஜⅣႺ⎇ⓥᚲᐕႎ P ၮ␆⊛㒰෰ታ㛎ሶ㧘⷏Ꮉ㓷㜞

╙ภ㧘-㧘

㔚᳇ㅘᨆⵝ⟎ߣ↢‛⣕⓸ⵝ⟎ߦࠃࠆ⎣ 㚍႐⟵ノ㧘᧻የብ㧘⍹ᯅⲢሶ㧘᳗ᷗ⟵ ᳓ⅣႺቇળ⹹㉄ᕈ⓸⚛ᳪᨴ࿾ਅ᳓ߩࠝࡦࠨࠗ࠻ᵺൻ

㧔㧕㧘

P ቁ㧘㜞ᯅᵗሶ㧘㊁ਛା৻㧘ᐔ↰ஜᱜ㧘 -㧘
⷏Ꮉ㓷㜞⑔ጟ⋵ߦ߅ߌࠆᨋ࿾߆ࠄߩ BOD㧘COD㧘 ᳗ᷗ⟵ቁ㧘᧻የብ㧘૒‫ᧁޘ‬㊀ⴕ

⑔ጟ⋵଻ஜⅣႺ⎇ⓥᚲᐕႎ P ో⓸⚛෸߮ో࡝ࡦߩᵹ಴⽶⩄╙ภ㧘-㧘
Tanaka Nobuhiro

The mutagenicity of amino-derivatives of Yoshito
diphenyl

ether

herbicidesinShimizu

Water

Sciencea n d P 

new Hiroko Tsukatani Nobuyuki Sera and Technology  - 
- 

Salmonella typhimurium YG tester strains Shigeji Kitamori
Estimation of orgnophosphoric acid

Makoto Nagase Mineki Toba Hiroyuki Analytical SciencesVol P 

triesters in soft polyurethane foam using

Kondo Akio

a concentrated sulfuric acid dissolution

HasebeYasuhara 㧖 andKiyoshiNo -㧘

㧖

technique and gas chromatography with㧖 National Institute for Environmental

flame photometric detection

Studies㧘㧖 Fuji Women's University⑔ጟ⋵ౝዊᴡᎹߩᄢဳᐩ↢േ‛⋧ጊፒᱜᢅ㧘✜ᣇஜ㧘᧖ᵏᤘ⑔ጟ⋵଻ஜⅣႺ⎇ⓥᚲᐕႎ P ╙ภ㧘-㧘

⑔ጟ⋵ਅߩᴡᎹḮᵹㇱߩᄢဳᐩ↢േ‛ ✜ᣇஜ㧘᧖ᵏᤘ㧘ጊፒᱜᢅ⑔ጟ⋵଻ஜⅣႺ⎇ⓥᚲᐕႎ P ⋧╙ภ㧘-㧘

ਛ࡮ዊဳߩ᳓↢ࠞࡔࡓࠪ⋡ࠍ↪޿ߚ↢ ✜ᣇஜᣣᧄⅣႺᲥᕈቇળ㧔✬ 㧕㧘 P ᘒᓇ㗀⹏ଔ⹜㛎↢ᘒᓇ㗀⹜㛎ࡂࡦ࠼ࡉ࠶ࠢ
ᦺୖᦠᐫ㧘pp-

⸘㧔⺰ᢥ╬⊒⴫৻ⷩ㧕-  -

ઙ㧔㧞㧕⊒⴫⺰ᢥᛞ㍳ 㒐㖸ოߩㆤ㖸ᕈ⢻ߦ෸߷ߔ㖸Ḯᜰะᕈߩᓇ㗀 A Longitudinal Analysis on the Association of Serum᧻ᧄḮ↢㧘⮮ේᕶม 㧦⿥㖸ᵄ࠹ࠢࡁ㧘 Vol㧘 No㧘

Lipids and Lipoproteins Concentrations with Blood

-㧘

Polychlorinated Biphenyls level in Chronic "Yusho"㧖㒐㖸ოߩᝌ౉៊ᄬࠍ㖸Ḯߩᜰะᕈࠍ⠨ᘦߒߡᬌ⸛ߒ

Paitientsߚ㧚߹ߕ㧘ᄢ߈ߐࠍήⷞߢ߈ߥ޿ᜰะᕈ㖸Ḯߩ଀ߣߒ

Shoji Tokunaga 㧖  Kyoichiro Kataoka㧦 ⑔ጟකቇ㔀⹹㧘ߡ㧘ᑪ‛߆ࠄߩᄖოㅘㆊ㖸ࠍขࠅ਄ߍߚ㧚ౝㇱࠍ᜛ᢔ  㧘-㧘

㖸႐ߣ઒ቯߒ㧘ㅘㆊ㖸ࠍᄖㇱ㖸႐߳ߩ㖸ḮߣߒߡႺ⇇ᐕ߆ࠄᐕ߹ߢߩᐕ㑆ߩో࿖ᴤ∝ᖚ⠪ㅊ〔ⷐ⚛ᴺࠍㆡ↪ߔࠆᰴర㖸႐ࡕ࠺࡞ߦࠃࠅ㧘㒐㖸ოߩᬌ⸻ߩ⚿ᨐࠍ߽ߣߦ㧘⑔ጟ⋵ߣ㐳ፒ⋵ߢⷰኤᦼ㑆ਛᝌ౉៊ᄬ߇♖ᐲ⦟ߊౣ⃻ߢ߈ࠆߎߣࠍ␜ߒߚ㧚࿁એ਄ฃ⸻ߒߚ⹺ቯᖚ⠪ߦߟ޿ߡ㧘⚻ᤨ⊛ߦ➅ࠅ㄰ߒ߹ߚ㧘ෘߺ߇චಽ⭯ߊ೰ߥ㓚ოߦ㑐ߒߡ㧘㖸Ḯᜰะ᷹ቯߐࠇߚⴊਛ PCB Ớᐲߣ✚㩄㩤㩇㩍㩥㨺㩣㧘 HDL 㩄㩤㩇㩍㩥㨺㩣ᕈ߇㒐㖸ოߩㆤ㖸ലᨐߦ෸߷ߔᓇ㗀ߦߟ޿ߡᬌ⸛ߒߚ㧚෸߮ਛᕈ⢽⢌ߣߩ㑐ㅪࠍ⛔⸘ቇ⊛ߦ⠨ኤߒߚ㧚ߘߩ⚿ߘߩ⚿ᨐ㧘ᄢ߈ߐ߇චಽዊߐߊ㧘ߒ߆߽ࠛ࠶ࠫ߹ߢߩ

ᨐ㧘ⴊਛ PCB Ớᐲ߇୚ߦߥࠆߣⴊᷡ㩄㩤㩇㩍㩥㨺㩣Ớᐲ߇〒㔌ߢᜰะᕈ߇቟ቯߔࠆ㖸Ḯߦኻߒߡߪ㧘ήᜰะᕈ㖸↵ߢ mg/dl㧘ᅚߢmg/dl ਄᣹ߒ㧘ⴊᷡਛᕈ⢽⢌ḮߣᲧセߒߚᝌ౉៊ᄬߩᏅ߇㧘ᜰะᕈ㖸࿶࡟ࡌ࡞Ꮕߦ

Ớᐲ߇↵ᕈߢ %㧘ᅚߢ %਄᣹ߔࠆߣផቯߐࠇ

ࠃࠅㄭૃߐࠇࠆߎߣࠍ␜ߒ㧘◲ᤃዉ಴ᑼࠍឭ᩺ߒߚ㧚ߚ㧚ㄭૃߩ♖ᐲߪ㧘ઔⷺ߇ᄢ߈ߊߥࠆ߶ߤዊߐߊߥࠆ߇㧘㧖 ਻Ꮊᄢቇ

࿾㕙ㄭறߢߪ໧㗴ߥ޿♖ᐲߢ޽ࠆߎߣࠍ⏕⹺ߒߚ㧚㧖 ਻Ꮊᄢቇ

 Uptake of polychlorinated dibenzo-p-dioxins and Ვ⩶ലജ⹜㛎↪ᬌᩏ᧚ᢱߣߒߡឭ಴ߐࠇߚᶖᲥ⮎ߦfurans in plant leavesᷙ౉ߒߡ޿ߚ࠮࡜࠴ࠕ⩶Takahiko Matsueda㧘 Yoichi Kurokawa㧘 Hironori Hirakawa㧘ၳᎹ๺⟤㧦ᣣᧄ㒐⩶㒐㤻ቇળ㔀⹹㧘㧘 -㧘㧚

Ryuichi Suda and Takao Iida㧦 ⑔ጟ⋵଻ஜⅣႺ⎇ⓥᚲᐕႎ㧘╙ภ㧘-㧘
᮸ᧁߩ⪲߳ߩ PCDDs ߣ PCDFs ߩ⫾Ⓧߩࡔࠞ࠾࠭ࡓ
ࠍ᣿ࠄ߆ߦߔࠆߚ߼㧘⒳㘃ߩ⪭⪲᮸㧔ࠗ࠴࡚࠙ߣࠕ
ࡔ࡝ࠞࡈ࠙㧕ߦߟ޿ߡ㧘 PCDDs ߣ PCDFs Ớᐲߩ⚻ᤨᐕᲕ⩶ലജ⹜㛎↪ᬌᩏ᧚ᢱߣߒߡឭ಴ߐࠇߚႮ
ൻࡌࡦࠩ࡞ࠦ࠾࠙ࡓ㧑ᶧߦ㧘㐿ኽ೨߆ࠄ⚦⩶ߦࠃߞߡᳪᨴߒߡ޿ߚ੐଀߇޽ߞߚ㧚ⵍᬌ᧚ᢱߩᳪᨴ⩶ߪ⣺ౝ⚦⩶⑼ߦዻߔࠆࠣ࡜ࡓ㒶ᕈߩ࠮࡜࠴ࠕ⩶ߢ㧘ᳪᨴ⩶ᄌൻࠍ⺞ߴߚ ⊒⧘⋥ᓟߩᣂ⧘ߦᲧセ⊛㜞Ớᐲߩᢙߪ㧘㧟 cfu/ml ߢ޽ߞߚ㧚࠮࡜࠴ࠕ⩶ߪ㒮ౝᗵᨴ

PCDDs ෸߮ PCDFs ߇ᬌ಴ߐࠇߚ ࠗ࠴࡚࠙ߪ಴⧘ᓟ

∝ߩේ࿃⩶ߣߒߡ߽㊀ⷐߢ޽ࠆ㧚߹ߚᧄ⩶ߪ᛫↢‛⾰ᣣ߹ߢ㧘ࠕࡔ࡝ࠞࡈ࠙ߪᣣ߹ߢỚᐲߩᷫዋ߇⷗ࠄ

߿ᶖᲥ⮎ߦኻߒߡ⠴ᕈࠍ␜ߔߎߣߢ߽⍮ࠄࠇߡ޿ࠆ㧚ࠇߚ߇㧘ߘߩᓟ㧘Ớᐲߩ਄᣹߇ⷰኤߐࠇߚߎߩỚᐲಽ㔌⩶ߪᏒ⽼Ⴎൻࡌࡦࠩ࡞ࠦ࠾࠙ࡓᶧߩ㧑ᶧ㧔ᦨ⚳ᄌൻߪ⍴ᨑߩᄖ⊹߆ࠄ⧘߳ߩ࠳ࠗࠝࠠࠪࡦߩ⒖േߣߘỚᐲ㧑ᶧ㧕ߢ߽Ვ⩶ലജ߇ߺࠄࠇߥ߆ߞߚ㧚ߩᓟߩ⪲ߩᕆᚑ㐳ߦࠃࠆᏗ㉼෸߮ᄢ᳇߆ࠄߩᴉ⌕ߦࠃࠆ߽ߩߣ⠨߃ࠄࠇߚ
ᣂ⧘ߩᄢ᳇߳ߩ᥸㔺ᦼ㑆߇⍴޿ߚ߼㧘ᣂ⧘ਛߩ࠳ࠗ
ࠝࠠࠪࡦߪᄢ᳇↱᧪ߣߪ⠨߃ࠄࠇߥ޿㧚ߎߩ⷗⸃ߩᅷ
ᒰᕈࠍ⹏ଔߔࠆߚ߼ߦ㧘⍴ᨑㇱ૏ߩ౻⧘㧘⨍෸߮⴫⊹ߦಽഀߒߡ㧘ฦ‫ߩޘ‬ㇱಽߩ PCDDs ෸߮ PCDFs ߩỚᐲߣหዻ૕ࡄ࠲࡯ࡦࠍ⸃ᨆߒߚ㧚ߘߩ⚿ᨐ㧘ᣂ⧘ߦ฽߹
ࠇࠆ PCDDs ෸߮ PCDFs ߩ↱᧪ߪ⴫⊹߆ࠄߩ⒖ⴕߣផቯߐࠇߚ㧚࿯ფਛߩ PCDDs ෸߮ PCDFs ߪᩮࠍ⚻↱ߒߡ⪲ߦỚ❗ߐࠇߥ޿ߣ⠨߃ࠄࠇߡ޿ࠆߎߣ߆ࠄ㧘⴫⊹ߦ฽߹ࠇࠆ PCDDs ෸߮ PCDFs ߪ⪲ߦ⫾Ⓧߐࠇߚ߽ߩ
߇⪭⪲೨ߦ⒖ⴕߒߚ߽ߩߣ⠨߃ࠄࠇߚ

 Vibrio cholerae O ᗵᨴ੐଀䋭⑔ጟ⋵ )%/5ߦࠃࠆㄘ૞‛ਛᱷ⇐ㄘ⮎ߩ৻ᢧಽᨆᴺߩᬌ⸛

ၳᎹ๺⟤㧘᧛਄శ৻㧘㐳㊁⧷ବ㧘ựፒశብ㧘⍹㤥㕏ዏ㧘⧃Ⴆ↱♿㧘ਛᎹ␞ሶ㧦⑔ጟ⋵଻ஜⅣႺ⎇ⓥᚲᐕႎ㧘╙⨹Ꮉ⧷ੑ 㧘ᷰㆺᴦ㓶 㧘ㄭ⮮ᱜᴦ 㧘᫪↰❥ 㧘ภ㧘-㧘

㧖

㧖

㧖

㧖

ේ৻⟤ 㧘ᳯፒᵏਯ 㧦∛ේᓸ↢‛ᬌ಴ᖱႎ㧘㧖ㄘ૞‛ਛߩᱷ⇐ㄘ⮎ࠬࠢ࡝࡯࠾ࡦࠣᴺߣߒߡ㧘ࠕ࠮㧖㧔㧕㧘㧘࠻࠾࠻࡝࡞㧛᳓᛽಴෸߮࿕⋧᛽಴▤♖⵾ߦࠃࠆᐕ᦬ᣣߦ Vibrio cholerae O ᗵᨴᖚ⠪߇⊒↢

GC/MS ߩ ৻ᢧಽᨆᴺࠍᬌ⸛ߒߚ㧚࡝ࡦ♽㧘Ⴎ⚛♽㧘ߒ㧘ᒰ⹥⩶ߪࠦ࡟࡜Ქ⚛↥↢ㆮવሶࠍ଻᦭ߒߡ޿ߚ㧚ࠞ࡯ࡃࡔ࡯࠻♽㧘ࡇ࡟ࠬࡠࠗ࠼♽╬ߩ⸘ㄘ⮎ߦߟ޿⃻࿷㧘ᗵᨴ∝ᴺ㘃ᗵᨴ∝ߣߒߡขࠅᛒߞߡ޿ࠆࠦ࡟

ߡ㧘ࠝ࡟ࡦࠫ㧘ࠠࡘ࠙࡝㧘₵☨ࠍ↪޿ߚᷝട࿁෼⹜㛎࡜ߪ Vibrio cholerae O෸߮ဳߩဳߢ޽ࠆ㧚ߒ߆ߒ㧘n= ࠍߘ ࠇ ߙ ࠇ Ბ 㓏 ߩ Ớ ᐲ ߢ ⴕ ߞ ߚ㧚ߘߩ⚿ᨐ㧘ߎࠇࠄဳએᄖߩ Vibrio cholerae ߦ ߽ࠦ࡟࡜Ქ⚛↥↢ㄘ⮎ߢ㧘ᱷ⇐ㄘ⮎ಽᨆᴺߩᮡḰ⊛⋡቟ߢ޽ࠆ㧑㧙ㆮવሶ଻᦭ᩣ߇޽ࠅ㧘੹ᓟ㘃ᗵᨴ∝ߣߒߡߩขࠅᛒ

㧑ߩ⦟ᅢߥ࿁෼₸߇ᓧࠄࠇ㧘ࠬࠢ࡝࡯࠾ࡦࠣᴺߣ

޿ߦߟ޿ߡᬌ⸛ߔࠆᔅⷐ߇޽ࠆߣ⠨߃ࠄࠇߚ㧚ߒߡߩ᦭↪ᕈ߇␜ߐࠇߚ㧚߹ߚ㧘ᧄᴺࠍ↪޿ߡ㧘⋵ౝ㧖 ࿖┙ᗵᨴ∝⎇ⓥᚲ

ߢ⾼౉ߒߚᨐታᬌ૕㧘㊁⩿ᬌ૕ࠍ⺞ᩏߒߚ⚿ᨐ㧘㧖 ਭ⇐☨⥃ᐥᬌᩏ࠮ࡦ࠲࡯

ᨐታߢߪࡉ࠼࠙ᬌ૕ߣࠗ࠴ࠧᬌ૕߆ࠄ㧘㊁⩿ߢߪ㧘㧖 ߐ߃߈ዊఽ⑼࡮ౝ⑼ක㒮࠽ࠬ㧘ࡇ࡯ࡑࡦ㧘⊕⩿ߩฦᬌ૕߆ࠄㄘ⮎߇ᬌ಴ߐࠇ
ߚ㧚ᬌ಴ߐࠇߚㄘ⮎ߪ㧘ࠕ࠮࠲ࡒࡊ࡝࠼㧘ࡇ࡝࠳ࡌࡦ㧘ࡈࠚ࠽࡝ࡕ࡞㧘ࡈ࡞ࡃ࡝ࡀ࡯࠻㧘ࠕ࠮ࡈࠚ࡯࠻㧘ࠫࠛ࠻ࡈࠚࡦࠞ࡞ࡉ㧘ࠗࡊࡠࠫࠝࡦ㧘ࡈࠚࡦࡃ࡟࡟࡯࠻ߢ㧘޿ߕࠇ߽ㄘ⮎ߩᱷ⇐ၮḰ୯એਅߩỚᐲߢ޽ߞߚ㧚 Structure activity relationship between Salmonella- ᴤ∝ᖚ⠪ⴊਛ࠳ࠗࠝࠠࠪࡦ㘃࡟ࡌ࡞ߩㅊ〔⺞ᩏmutagenicity and nitro-orientation of nitroazaphenanthrenes㧔ᐕ㧕㧘 Nobuyuki Sera㧘 Kiyoshi Fukuhara㧖㧘㘵↰㓉㓶㧘ᚭ㜞ዅ 㧖㧘ᐔᎹඳ઄㧘㘧⍹๺ᄢ㧘᧻ᨑ㓉

㧘 Shigeki Sasaki㧖㧦ᒾ㧘ၳዞ⧷㧘ਛᎹ␞ሶ㧘ฎᳯჇ㓉 㧖㧦⑔ጟකቇ㔀⹹㧘

Hiroshi Tokiwa

㧖Hideo Utsumi㧖㧖㧘 Naoki Miyata

Chemico-Biological Interactions㧘 㧘-㧘㧚  㧘-㧘㧚࠾࠻ࡠࠕࠩࡈࠚ࠽ࡦࠬ࡟ࡦ⺃ዉ૕⒳㘃㧘࠾࠻ࡠࠕᐔᚑᐕᐲߦᴤ∝ᖚ⠪ฬ߆ࠄࠗࡦࡈࠜ࡯ࡓ࠼ࠦࡦ

ࠩࡈࠚ࠽ࡦࠬ࡟ࡦࠝࠠࠪ࠼⺃ዉ૕⒳㘃ߦߟ޿ߡ㧘ᄌ࠮ࡦ࠻ࠍᓧߡណขߐࠇߚⴊᶧ߆ࠄ࠳ࠗࠝࠠࠪࡦ㘃ࠍ᷹⇣ේᕈ㧔 TA㧘 TA㧘 TANR㧘 TA / DNP 㧘 YG

ቯߒߚ㧚ߎߩಽᨆߪ㧘ᚒ‫߇ޘ‬㐿⊒ߒߚml ߩⴊᶧ߆ࠄ

㧘 YG㧘 YG㧘 YG㧕ࠍ᷹ቯߒ㧘‛ℂ࠳ࠗࠝࠠࠪࡦ㘃ࠍᬌ಴᷹ቯߔࠆ⿥ᓸ㊂㜞ᗵᐲㄦㅦಽᨆ

ൻቇ⊛ᕈ⁁ߣߩ㑐ㅪߦߟ޿ߡᬌ⸛ߒߚ㧚ߘߩ⚿ᨐ㧘ᄌᴺ ߢ ⴕ ߞ ߚ 㧚 PCB ߩ ࠟ ࠬ ࠢ ࡠ ࡑ ࠻ ࠣ ࡜ ࡓ ࡄ ࠲ ࡯ ࡦ⇣ේᕈߪᲣ㛽ᩰߦ⟎឵ߔࠆ⟎឵ၮߩ⟎឵ⷺᐲߣ⋧㑐ߔ

㧔 GC-ࡄ࠲࡯ࡦ㧕߇ A ࠲ࠗࡊࠍ␜ߔฬߩ✚ TEQ Ớࠆߎߣ߇᣿ࠄ߆ߣߥߞߚ㧚ᐲߩᐔဋ୯ߪpg TEQ/g lipid㧘 B ࠲ࠗࡊࠍ␜ߔฬ

㧖 Kyushu Women's Universityߪ  pg TEQ/g lipid㧘 C ࠲ ࠗ ࡊ ࠍ ␜ ߔ  ฬ ߪ  pg

㧖 National Institure of Health Sciences

TEQ/g lipid ߪpg TEQ/g lipid ߢ ޽ߞߚ㧚 GC ࡄ࠲࡯ࡦ㧖 Kyushu University߇ A ߅ࠃ߮ B ࠲ࠗࡊߩᖚ⠪ߪ৻⥸ੱߣᲧߴߡⴊਛ࠳

㧖 Nagoya City Universityࠗࠝࠠࠪࡦ㘃Ớᐲ߇߆ߥࠅ㜞޿߇㧘 C ࠲ࠗࡊߩᖚ⠪ߪ৻⥸ੱ ߣห⒟ ᐲߩ ୯ߢ޽ ߞ ߚ㧚 ⴊ ਛ࠳ࠗࠝࠠࠪࡦ㘃
TEQ Ớᐲߩౝ⸶㧔 PCDDs㧦 PCDFs㧦 non-ortho PCBs㧦
mono-ortho PCBs㧕 ߪ A ࠲ࠗࡊ෸߮ B ࠲ࠗࡊߩౝ⸶ߪ
߶ߣࠎߤหߓߢ㧘ߎࠇߪ৻⥸ੱߩߘࠇߣߪᄢ߈ߊ⇣ߥߞߡ޿ߚ㧚ઁᣇ㧘 C ࠲ࠗࡊߩౝ⸶ߪ৻⥸ੱߩߘࠇߦ㘃ૃߒߡ޿ߚ㧚㧖 ␠࿅ᴺੱ㧖 ਻Ꮊᄢቇ

ᣣᧄ㘩ຠⴡ↢දળ ⴊਛ2%$ࡄ࠲࡯ࡦ್ቯߦ߅ߌࠆᓥ᧪ᴺߣ⇣ᕈ૕೎ಽ New protocol of Dioxins analysis in human blood

ᨆᴺߩห╬ᕈߦߟ޿ߡ

Takashi Todaka 㧖 㧘 Hironori Hirakawa㧘 Kazuhiro TobiishiਛᎹ␞ሶ㧘⧃Ⴆ↱♿㧘ၳዞ⧷㧘ᐔᎹඳ઄㧘㘧⍹๺ᄢ㧘

and Takao iida㧦 ⑔ጟකቇ㔀⹹㧘  㧘-㧘㧚㘵↰㓉㓶㧦⑔ጟකቇ㔀⹹㧘  㧘-㧘

 g ߩⴊᶧ㊂ߢ࠳ࠗࠝࠠࠪࡦ㘃ಽᨆࠍน⢻ߦߔࠆ᷹ᴤ∝ᖚ⠪ߩⴊਛ PCB ߩࡄ࠲࡯ࡦ್ቯߦߟ޿ߡ㧘ᓥቯ♽߅ࠃ߮ⴊᶧ⹜ᢱߩ೨ಣℂᴺࠍᬌ⸛ߒߚ㧚ߔߥࠊߜ㧘᧪ ᴺ ߢ ޽ ࠆ ࡄ ࠶ ࠢ ࠼ ࠞ ࡜ ࡓ -㔚 ሶ ᝝ ₪ ဳ ᬌ ಴ ེ㜞ㅦṁᇦ᛽಴ⵝ⟎ߦࠃࠆⴊᶧ⹜ᢱ߆ࠄߩ⢽⾰ߩ᛽಴ᴺ㧘㧔 ECD㧕 ઃ߈ࠟࠬࠢࡠࡑ࠻ࠣ࡜ࡈ㧔 GC㧕 㧔ᮡḰຠߣ

ᓥ᧪ᴺߩ /ࠬࠤ࡯࡞ߢߩࠞ࡜ࡓࠢ࡝࡯ࡦࠕ࠶ࡊᴺ߅ߒߡ KC-:KC- = :ߩᷙวṁᶧࠍ↪޿ߚࡄ࠲࡯ࡦ

ࠃ߮ᄢ㊂ṁᇦᵈ౉ⵝ⟎㧔 SCLV InjectionSystem㧕 ࠍⵝ஻

วࠊߖᴺ㧕ߣࠠࡖࡇ࡜࡝࡯ࠞ࡜ࡓ -GC/㜞ಽ⸃⢻⾰㊂ಽ

ߒߚ HRGC/HRMS ࠍ ↪޿ߡ㜞ᗵᐲ᷹ቯߩ৻ㅪߩಽᨆ

ᨆ⸘㧔 HRGC/HRMS㧕 ߦࠃࠆ⇣ᕈ૕೎ಽᨆᴺߣߩห╬

ᣇᴺߦߟ޿ߡᬌ⸛ߒ㧘⿥㜞ᗵᐲㄦㅦಽᨆᴺࠍ⏕┙ߒߚ㧚ᕈߦߟ޿ߡᬌ⸽ߒߚ㧚ࡄ࠲࡯ࡦ್ቯߪ㧘 A ෶ߪ B ࡄ࠲ᄢ㊂ṁᇦᵈ౉ⵝ⟎ߩⵝ஻ߦࠃࠅ HRGC/HRMS ߩ ⋧ኻ࡯ࡦߦߟ޿ߡߪ㧑㧘 C ࡄ࠲࡯ࡦߦߟ޿ߡߪ㧑ᗵᐲߪ㧝㧜୚⒟ᐲะ਄ߒߚ㧚ห৻ߩⴊᶧࠍ↪޿ߡⴕߞߩ৻⥌₸ࠍ␜ߒ㧘ਔ⠪ߩᣇᴺߢห╬ᕈ߇⹺߼ࠄࠇߚ㧚

ߚᓥ᧪ᴺߣߩᲧセᬌ⸛⚿ᨐ߆ࠄ㧘 g ߩⴊᶧ㊂ߢ࠳ࠗߎࠇߦࠃࠅ㧘ࠃࠅᲥᕈ⹏ଔ߇ᱜ⏕ߦߢ߈ࠆ⇣ᕈ૕೎ಽࠝࠠࠪࡦ㘃Ớᐲ߇චಽ᷹ቯน⢻ߢ޽ࠆߎߣ߇⏕⹺ߐࠇ

ᨆᴺ߳ߩ⒖ⴕ߇น⢻ߢ޽ࠆߎߣ߇␜ߐࠇߚ㧚ߚ㧚ߐࠄߦ㧘ᓥ᧪ᴺߦᲧߴⴊᶧ⹜ᢱߩ೨ಣℂᲑ㓏ߢ⾌߿ߔᤨ㑆ࠍᄢ ᏷ߦ⍴❗ߔࠆߎߣ߇ߢ߈ߚ㧚ᧄᴺߪ g⒟ᐲߩዋ㊂ߩⴊᶧ㊂ߢ࠳ࠗࠝࠠࠪࡦ㘃ࠍ᷹ቯߢ߈ࠆߛ
ߌߢߥߊ㧘ᄙᢙߩࠨࡦࡊ࡞ࠍല₸ࠃߊ㧘߆ߟㄦㅦߦಣ
ℂߔࠆߩߦലᨐ⊛ߥᣇᴺߢ޽ࠆ㧚㧖 Japan Food Hygiene Association

 Measurement of blood dioxin in human blood : Frequency of SCEs in Japanese Infants Lactatioally

Improvement of analytical Method

Exposed to Organochlonone Pesticides

Takao iida and Takashi Todaka 㧦 Industrial Health㧘 Vol

Junya Nagayama 㧖  㧘 Mayumi Nagayama 㧖  㧘 Reiko No -㧘㧚

Nakagawa㧘 Hironori Hirakawa 㧘 Takahiro Matsueda Takao㧖ᣣᧄో࿖ߩᴤ∝ᖚ⠪ߩⴊਛ࠳ࠗࠝࠠࠪࡦỚᐲࠍㄦㅦߦ᷹ቯߔࠆߚ߼㧘㜞ㅦṁᇦ᛽಴ᴺ㧘ᄢ㊂ṁᇦᵈ౉ⵝ⟎

Iida and Jun'ichiro Fukushige 㧖 㧦⑔ጟකቇ㔀⹹㧘  㧘- 

ઃ߈ GC/MS ෸߮ࠞ࡜ࡓࠢ࡝࡯ࡦࠕ࠶ࡊ♽ߩ࠳࠙ࡦࠨ

ࡅ࠻Უ੃ਛߦߪ᭽‫ߥޘ‬ൻቇᳪᨴ‛⾰߇ᱷ⇐ߒߡ޿ࠆࠗࠫࡦࠣߦࠃࠆ⿥ᓸ㊂ㄦㅦᐩ≮ᴺࠍ⏕┙ߒߚ㧚⃻࿷‫ޔ‬ߎߣ߇ࠊ߆ߞߡ޿ࠆ㧚੹࿁㧘ஜᐽߥᲣⷫ߆ࠄណขߒߚ

ᴤ∝ᖚ⠪⚂ฬߩⴊਛ࠳ࠗࠝࠠࠪࡦࠍߎߩᣇᴺߦࠃ

Უ੃ਛߦᱷ⇐ߔࠆ DDT㧘 HCH ╬ߩㄘ⮎Ớᐲߣ᝼੃ࠍ

ߞߡಽᨆਛߢ޽ࠆ㧚ฃߌߚ੃ఽߩⴊᶧਛ SCE ߩ⚵ߦߟ޿ߡ㧘ߘߩ⋧㑐㧖 Japan Food Hygiene Associationࠍ⺞ߴߚ㧚ߘߩ⚿ᨐ㧘 DDT ߿ HCH ߩჇടߦࠃߞߡ㧘
SCE ߇ ᓇ㗀ࠍฃߌߡ߅ࠅ㧘૗ࠄ߆ߩㆮવᲥᕈ߇޽ࠆ
ߎߣ߇␜ໂߐࠇߚ㧚㧖 Kyushu University㧖 Fukuoka Children's Hospital 51㧘01Zࠍ㒰෰ߢ߈ࠆᣂߒ޿㜞ᵴᕈ὇⚛❫⛽ Mutagenic activity in roadside soilsਅේቁ┨㧦‫ޟ‬࿑⸃ࠛࠦࡑ࠹ࠖ࡝ࠕ࡞ߩߔߴߡ‫ޠ‬㧙Ⅳ

Hiroko Tsukatani㧘 Yoshito Tanaka㧘 Nobuyuki Sera㧘Ⴚᣂ᧚ᢱ⎇ⓥળ✬㧙㧘Ꮏᬺ⺞ᩏળ㧘 p-㧘

Nobuhiro Shimizu㧘 Shigeji Kitamori㧘 Naohide Inoue 㧖 㧦㜞ᵴᕈ὇⚛❫⛽ߪశᾖ኿ࠍᔅⷐߣߖߕ㧘ቶ᷷ઃㄭߩThe Journal of Toxicological Sciences㧘 Vol㧘 No㧘᷷ᐲߢ㧘ⅣႺⓨ᳇ਛߩ⓸⚛㉄ൻ‛㧘ੑ㉄ൻ⎫㤛㧘ᓸ㊂

-㧘

ൻቇ‛⾰ߥߤࠍๆ⌕㧘㒰෰ߔࠆఝࠇߚ⢻ജࠍ߽ߞߡ޿

ਭ⇐☨Ꮢౝᐙ✢㆏〝ߩਛᄩಽ㔌Ꮺ㧘ᱠ㆏෸߮㆏〝ᴪࠆ㧚߹ߚ㧘ᦨㄭߦߥߞߡ㧘㜞ᵴᕈ὇⚛❫⛽ߪ⓸⚛㉄ൻ޿౏࿦ౝߩ࿯⍾⹜ᢱߩᄌ⇣ේᵴᕈࠍ Ames ࠹ࠬ࠻ߦࠃ

‛ࠍήኂߥ⓸⚛ࠟࠬߣ᳓ߦಽ⸃ߢ߈ࠆ⸅ᇦ⊛ߥ૞↪ࠍࠅ⺞ᩏߒߚ㧚߹ߚ㧘ᄙⅣ⧐㚅ᣖ὇ൻ᳓⚛㘃㧔 PAHs㧕

ⅣႺ

෸߮㊀㊄ዻỚᐲ߽⺞ߴߚ㧚ߘߩ⚿ᨐ㧘ࡀ࠭ࡒ࠴ࡈࠬ⩶ౣ↢଻ోᯏ᭴㧔ᣥ‫౏ޟ‬ኂஜᐽⵍኂ⵬ఘ੍㒐දળ‫ޠ‬㧕߆TA㧘 TAᩣߦኻߒߡᄌ⇣ේᵴᕈ߇⹺߼ࠄࠇ㧘ᄌࠄߩฃ⸤⎇ⓥߣߒߡ㧘਻Ꮊᄢቇߣߩ౒ห⎇ⓥߦࠃࠅߘ⇣ේᵴᕈ߇㜞޿߽ߩ߶ߤ PAHs㧘㊀㊄ዻỚᐲ߽㜞ߊߥߩᵺൻᯏ⢻ࠍะ਄ߐߖࠆߚ߼ߩᛛⴚᡷ⦟㧘ታ⸽ൻߦะ

ࠆ௑ะ߇ߺࠄࠇߚ㧚߹ߚ㧘 YG ᩣߢࠃࠅ㜞޿ᵴᕈࠍ␜

ߌߚ⺞ᩏ⎇ⓥࠍⴕߞߡ޿ࠆ㧚ߒߚߎߣ߆ࠄ㧘࠾࠻ࡠࠕ࡟࡯ࡦ㧘ࡅ࠼ࡠࠠࠪ࡞ࠕࡒࡦ

߽ߟߎߣ߇ಽ߆ߞߡ߈ߚ㧚⃻࿷㧘⁛┙ⴕ᡽ᴺੱ

ߩሽ࿷߇␜ໂߐࠇߚ㧚ߐࠄߦ㧘ਛᄩಽ㔌Ꮺ㧘ᱠ㆏㧘౏࿦ౝߩ㗅ߦᄌ⇣ේᵴᕈ㧘 PAHs ෸߮㊀㊄ዻỚᐲ߇ૐߊߥࠆ௑ะ߇ߺࠄࠇ㧘᮸ᧁߦࠃࠆᓇ㗀޽ࠆ޿ߪ〒㔌ߦࠃࠆᷫ⴮߇⠨߃ࠄࠇߚ㧚㧖 Kyushu University⑔ጟ⋵ߦ߅ߌࠆቶౝൻቇ‛⾰ߩታᘒ⺞ᩏ Validity of mutagenic activity as an indicator of riverജኼ 㓶 㧘ᩉ Ꮉ ᱜ ↵㧘 ự ᧛ ⎇๋㧘 ᄢ⍹ ⥝ᒄ㧘 ጤᧄ⋿

water pollutionੑ㧘ਛ᧛෶ༀ 㧦⑔ጟ⋵଻ஜⅣႺ⎇ⓥᚲᐕႎ㧘╙ภ㧘

Hiroko Tsukatani㧘 Yoshito Tanaka㧘 Nobuyuki Sera㧘-㧘

Nobuhiro Shimizu㧘 Shigeji Kitamori㧘 Naohide Inoue 㧖 㧦ᣂ▽૑ቛ䈮䈍䈔䉎✚ើ⊒ᕈ᦭ᯏ‛㩿㪫㪭㪦㪚㪒㪫㫆㫋㪸㫃 㫍㫆㫃㪸㫋㫀㫃㪼

Environmental Health and Preventive Medicine㧘 Vol 㧘㫆㫉㪾㪸㫅㫀㪺 㪺㫆㫄㫇㫆㫌㫅㪻㫊㪀䉕᭽䇱䈭ಽᨆᣇᴺ䈪᷹ቯ䈜䉎䈖䈫䈮No㧘-㧘

䉋䉍䋬㪫㪭㪦㪚䈮䈧䈇䈩䋬᷹ቯᣇᴺ䈱⏕┙䋬ታᘒ䈱ᛠី䉕⋡ᄌ⇣ේᕈ⹜㛎ߩ᳓⾰ᳪỘᜰᮡߣߒߡߩ㊀ⷐᕈࠍ᣿ࠄ

⊛䈫䈚䈢⺞ᩏ䉕⑔ጟ⋵ౝ䈱ో㪈㪌ᚭ䈱૑ቛ䈮䈍䈇䈩ታᣉ䈚߆ߦߔࠆߚ߼ߦ㧘਻Ꮊർㇱ࿾ၞߩᴡᎹߢណขߒߚࡉ࡞

䈢䋮ើ⊒ᕈ᦭ᯏൻว‛㩿㪭㪦㪚䋻㪭㫆㫃㪸㫋㫀㫃㪼 㫆㫉㪾㪸㫅㫀㪺 㪺㫆㫄㫇㫆㫌㫅㪻࡯࡟࡯࡛ࡦ᛽಴‛ߩᄌ⇣ේᵴᕈࠍ⺞ߴ㧘ᓥ᧪ߩ᳓⾰ᳪ㫊㪀䈮䈧䈇䈩䈲䋬䉝䉪䊁䉞䊑ᴺ䈮䉋䉍㪈㪈㪍ᚑಽ䈏ቯ㊂น⢻䈪Ộᜰᮡߩ୯ߣߩᲧセࠍⴕߞߚ㧚⹜ᢱ᛽಴‛ߩਛߢࡀ࠭

䈅䈦䈢䈏䋬䊁䊦䊕䊮㘃䈱ቯ㊂䈮䈲㪉⒳㘃䈱᝝㓸▤䈱૬↪

ࡒ࠴ࡈࠬ⩶ YG㧘 YGᩣߦኻߒߡઁߩ⹜ᢱࠃ

䈏ᔅⷐ䈪䈅䈦䈢䋮䉁䈢䋬䊌䉾䉲䊑ᴺ䈮䉋䉍䊊䊨䉭䊮ൻ὇ൻࠅ߽㜞޿ᄌ⇣ේᵴᕈࠍ␜ߔ߽ߩ߇⏕⹺ߐࠇߚ㧚੹࿁ߩ᳓⚛㘃䉇䉣䉴䊁䊦㘃䈱ⓨ᳇ਛỚᐲ䉕ផ᷹䈜䉎䈖䈫䈏น⢻⹜ᢱߦߟ޿ߡ㧘ᄌ⇣ේᵴᕈߣᓥ᧪ߩ᳓⾰ᳪỘᜰᮡߣߩ䈪䈅䈦䈢䋮ᧄ⺞ᩏ⚿ᨐ䈎䉌䋬㪫㪭㪦㪚୯䈱㜞䈇૑ቛ䈲▽㪊䊱㑆ߦߪ․ߦ⋧㑐ߪߺࠄࠇߥ߆ߞߚߎߣ߆ࠄ㧘ᓥ᧪ߩ᳓᦬એౝ䈱ᣂ▽૑ቛ䈏ਛᔃ䈪䈅䈦䈢䈏䋬⍹ᴤ♽ᥦᚱౕེ⾰ᳪỘᜰᮡߦࠃࠅᄌ⇣ේᵴᕈࠍ੍᷹ߔࠆߎߣߪ࿎㔍ߢ䈱૶↪䈱ᓇ㗀䉅䈅䉎䈫ផኤ䈘䉏䈢䋮䉁䈢䋬ቶౝⓨ᳇ਛਥⷐ޽ࠆߎߣ߇␜ໂߐࠇߚ㧚ߎࠇࠄߩ⚿ᨐ߆ࠄ㧘ᄌ⇣ේᕈ‛⾰䈮䈧䈇䈩䋬ੱ䈱䋱ᣣๆ౉᥸㔺㊂䈱ផቯ䉕ⴕ䈦䈢䋮⹜㛎ߩࠃ߁ߥ↢‛⹜㛎ߦࠃࠆ⹏ଔߪ᳓⾰ᳪỘᜰᮡߣߒߡ㊀ⷐߢ޽ࠆߣ⠨߃ࠄࠇߚ㧚㧖 Kyushu University ඳᄙḧߦ߅ߌࠆࡎ࠻࠻ࠡࠬࠟࠗ߇⽺㉄⚛᳓႙ߦਈ Seasonal variation of  Be deposition in Japan߃ࠆᓇ㗀Yukinori Narazaki 㧘 Kazunobu Fujitaka 㧖  㧘 Shuichiᾢ⼱ඳผ㧘ጊፒᗅ⟵ 㧖㧘ᷰㄝ੫৻ 㧖㧘⮮↰ஜ৻ 㧖㧦

Igarashi 㧖  㧘 Yoichi Ishikawa 㧖  㧘 Naoto Fujinami 㧖  㧦ⅣႺᎿቇ⎇ⓥ⺰ᢥ㓸㧘㧘-㧘

Journal of Radioanalytical andNuclear Chemistry㧘 㧘ඳᄙḧߦ߅ߌࠆࡎ࠻࠻ࠡࠬࠟࠗߩᶖ㐳ߩ᜼േࠍ⍮ࠆ-㧘

ߚ߼㧘ߘߩಽᏓࠍ⺞ᩏߒߚ㧚ࡎ࠻࠻ࠡࠬࠟࠗߪ⽺㉄⚛

㧙ᐕߦ߅޿ߡᣣᧄߩㇺ㆏ᐭ⋵㧔ࠑ'N㧘᳓႙ߩ⊒↢ߒߥ޿᧦ઙਅߢᐕ㑆ഀㄭߊ߇ᱫ੢ߒߡ޿

ࠑ 'E-ࠑ 'N㧘ࠑ 'E㧕ߦ㒠ਅߒߚ Be ߩ㐳ߚ㧚߹ߚ㧘ᓧࠄࠇߚᲖ㐳㧙୘૕ᢙಽᏓࠍ߽ߣߦ୘૕ᢙ

ᦼᄌേ߆ࠄ࿾ၞߏߣߩቄ▵ᄌേࠍ᣿ࠄ߆ߦߒߚ㧚ർ㒽ߩᢙ୯⸘▚ࠍⴕ޿㧘߅߅߻ߨߘߩቄ▵ᄌൻࠍౣ⃻ߢ߈ࠍਛᔃߣߒߚᣣᧄᶏ஥ߩ࿾ၞߪ౻ߦࡇ࡯ࠢࠍ␜ߔ

ߚ㧚ߐࠄߦ㧘Ზ㐳㧙ੇ῎り⾰㊂ߩࠕࡠࡔ࠻࡝࡯ᑼࠍ↪

Winter peak㧘 ᄥᐔᵗ஥ߩ᧲ᣣᧄߢߪ Spring peak ߣ ᦬޿ߡ㧘ฦ࿾ὐ࡮ฦ᦬ߩࡎ࠻࠻ࠡࠬࠟࠗߩᱫ੢ᢙ࡮ੇ῎ߦࡇ࡯ࠢࠍ␜ߔ Double peaks㧘 ⷏ᣣᧄߢߪ Spring peakᱫ੢⾰㊂ࠍ▚ቯߒߚ߁߃ߢ㧘ࡎ࠻࠻ࠡࠬࠟࠗߩ CNPߛߌࠍ␜ߔ Single peak㧘 ౝ㒽ਛᄩᏪߢߪ Non peak ߩ฽᦭㊂ࠍ↪޿ߡ㧘ߘࠇࠄࠍᅢ᳇⊛ߦಽ⸃ߔࠆ਄ߢᔅⷐ

ᒻࠍ␜ߒߚ㧚㩊㨼㩖㩩ߩቄ▵ᄌേߪᄢ᳇ਛߩ  Be Ớᐲߦߥ㉄⚛㊂ࠍផቯߒߚ㧚ߘߩ⚿ᨐ㧘᥅⑺ߦ⿠ߎࠆ⽺㉄⚛

ᔅߕߒ߽ᡰ㈩ߐࠇߕ㧘྾ቄߩᄌൻߦࠃࠆᄢ᳇ߩᵹࠇ╬᳓႙ߦࠃࠆࡎ࠻࠻ࠡࠬࠟࠗߩ⛘Ṍߪ⽺㉄⚛᳓႙ߩੑᰴ

ߩ᳇⽎ቇ⊛࿃ሶ߿ዪ࿾⊛ߥ࿾ᒻߦࠃߞߡ⋧㆑߇↢ߓ㧘⊛ⵍኂࠍ᜛ᄢߔࠆߎߣ߇ᗐቯߐࠇߚ㧚৻ㇱߢߪ㒠᳓㊂ߣߩ㑐ଥ߽⹺߼ࠄࠇߚ㧚㧖 ⑔ጟᄢቇ

㧖 National Institute of Radiological Sciences㧖 ਻ᎺⅣႺ▤ℂදળ㧖 Fukui Prefectural Environmental Radiation Monitoring
Center㧖 Environmental Radioactivity Research Institute of Miyagi
㧖 Kyoto Prefectural Institute of Hygienic and Environmental
Sciences ⑔ጟ⋵ߦ߅ߌࠆ 5T෸߮ %UߩỚᐲಽᏓߣផ⒖ Ꮏ႐ឃ᳓ಣℂᣉ⸳ߦ㑐ߔࠆᛛⴚ⋧⺣੐଀㧙๧ཬ⵾㧔㧙ᐕ㧕ㅧ੐ᬺ႐ߩᵴᕈᳪᵆߩ▤ℂߣో࡝ࡦߩ㑐ଥ㧙ᬰፒᐘ▸㧘↰਄྾㇢㧦଻ஜ‛ℂ㧘㧘-㧘

ᾢ⼱ඳผ㧘ᔒ᳓ାᒄ㧘᳗ᷗ⟵ቁ㧘᧻የብ㧘ਛ᧛෶ༀ㧘㧙ᐕߩⅣႺ㧔㒠ਅ‛㧘࿯ფ㧘ᣣᏱ㘩㧘㒽⧯᧻⟤⍮ሶ 㧦⑔ጟ⋵଻ஜⅣႺ⎇ⓥᚲᐕႎ㧘╙ภ㧘᳓㧘ᶏ᳓෸߮ᶏᐩ࿯㧕ਛ  Sr㧘 Cs ߩಽᨆ⚿ᨐࠍኻ⽎-㧘

ߦⅣႺਛߢߩỚᐲಽᏓߣ․ᓽࠍ⸃ᨆߒߚ㧚ฦ⹜ᢱਛߩ

㧖ో࡝ࡦߩឃ᳓ၮḰ୯ࠍ⿥ㆊߒߚ๧ཬ⵾ㅧᬺ⠪ߩේ࿃Sr㧘  Cs ߪ✭߿߆ߥ⚻ᐕᷫዋ௑ะ߇⹺߼ࠄࠇࠆ㧚㒠ⓥ᣿ࠍⴕ߁ߚ߼ߦឃ᳓ಣℂ⺞ᩏࠍⴕߞߚ㧚ฦᎿ⒟ߩឃ

ਅ‛ਛߩ Sr ߪᐕએ㒠ᬌ಴ߐࠇߕ㧘 Cs ߽Ꮧߢ޽಴᳓෸߮ឃ᳓ಣℂᣉ⸳ߩᵴᕈᳪᵆࠍಽᨆߒߚ㧚ߘߩ⚿ߞߚ㧚࿯ფਛߩ Sr㧘  Cs ߪ㐳ᦼߦᱷ⇐ߒߡ޿ߚ㧚⴫ᨐ㧘⺞ᩏߒߚฦᎿ⒟ឃ᳓࡮ᵴᕈᳪᵆߩ‛ℂ⊛ᕈ⁁ߦ໧ጀ࿯ფਛߩ Sr㧘 Cs ỚᐲߪᐔဋBq/kg ੇ࿯෸߮ᐔ

㗴ߪߥ߆ߞߚ㧚৻ᣇ㧘ᦑ᳇ᮏߩᵴᕈᳪᵆਛߩ࡝ࡦ฽᦭

ဋ Bq/kg ੇ ࿯ߢ޽ߞߚ㧚ㇺᏒㇱߣṪ᧛ㇱߩᣣᏱ㘩㊂ߪ৻⥸ߩ୯ࠃࠅૐߊ㧘ᦑ᳇ᮏਛߩṁሽ㉄⚛߽ਇ⿷ߔਛߩ  Sr㧘 Cs Ớᐲߩ᦭ᗧߥᏅߪ㘩੐ౝኈ߿㘩੐㊂߇ࠆ௑ะߦ޽ߞߚ㧚ේ࿃ߪ㜞Ớᐲߦሽ࿷ߒߡ޿ߚᦑ᳇ᮏ

ේ࿃ߣ⠨߃ࠄࠇߚ㧚㒽᳓෸߮ᶏ᳓ਛߩ Sr Ớᐲߦ᦭ᗧౝߩᵴᕈᳪᵆ߇㧘㑆ᰳᦑ᳇ߩណ↪࡮ᦑ᳇ⵝ⟎ߩਇౕวᏅߪߥ߆ߞߚ㧚ᶏ᳓ਛߦᬌ಴ߐࠇࠆ  Cs ߪ㒽᳓ਛߦ╬ߩේ࿃ߦࠃࠅህ᳇⊛᧦ઙਅߦ߅߆ࠇߚὑߦ㧘㜞Ớᐲߪᬌ಴ߐࠇߥ߆ߞߚ㧚৻ᣇ㧘ᶏᐩ࿯ਛߦ Sr ߪᬌ಴ߐߩᵴᕈᳪᵆਛ߆ࠄ᳓ਛ߳ߩᄢ㊂ߩ࡝ࡦߩ᡼಴߇⿠ߎߞ

ࠇߥ޿߇㧘  Cs ߪᬌ಴ߐࠇ㧘ਔᩭ⒳ߩ᜼േߦߪ⪺ߒߚߚ߼ߣផኤߐࠇߚ‫ᦑޕ‬᳇㊂Ⴧട࡮ᳪᵆߩᒁ߈ᛮ߈╬޿Ꮕ⇣߇⹺߼ࠄࠇߚ㧚ߩឭ᩺ࠍⴕߞߚߣߎࠈ㧘ᵴᕈᳪᵆਛߩ࡝ࡦ฽᦭㊂߽Ⴧടߒ㧘᡼ᵹ᳓ਛߩో࡝ࡦỚᐲ߽ᄢ᏷ߦૐਅߒߚ㧚㧖 ጊ㐷଻ஜ⑔␩ⅣႺ੐ോᚲ 㒠ਅ‛ਛߩ᡼኿⢻᷹ቯߦ߅ߌࠆᄢ㒽⿠Ḯࠛࠕࡠ࠱ ࿾ਅ᳓ਛ࡜࠼ࡦỚᐲ᷹ቯⵝ⟎ߩᲧセ 㧙ᶧ૕ࠪࡦ࠴

࡞ߩᓇ㗀㧔╙㧞ႎ㧕࡟࡯࡚ࠪࡦࠞ࠙ࡦ࠲㧘+/ᴰല⸘㧘㔚㔌▫㧘࡜࠼ࡦࡕ࠾

⍹Ꮉ㓁৻ 㧘ᧁ┙ඳ 㧘દ⮮▵↵ 㧘૒‫ᧁޘ‬ବⴕ 㧘ᬰ࠲ߢᓧࠄࠇߚ⚿ᨐ㧙ፒᐘ▸㧘↰਄྾㇢㧘㋈ᧁ೑ቁ 㧦ችၔ⋵ේሶജ࠮ࡦ࠲

⍹Ꮉᔀᄦ 㧖㧘቟ጟ↱⟤ 㧖㧘ᬰፒᐘ▸㧘ᐥᰴ⋿ม 㧖㧘࡯ᐕႎ㧘╙Ꮞ㧘-㧘⍹੗ᔘ 㧖㧘㗇↰ඳᢥ 㧖㧘ጊ↰⵨ม 㧖㧦 Radioisotopes㧘 㧘

㧖

㧖

㧖

㧖

㧖

ᐕએ㒠ߩᤐᦼࠍਛᔃߣߒߡ㧘ࠕࠫࠕᄢ㒽߆ࠄ-㧘

ߩࠛࠕࡠ࠱࡞ 㤛⍾ ߦߣ߽ߥ߁㒠ਅ‛⹜ᢱਛߦߪ Cs

᳓ ਛ࡜࠼ ࡦỚᐲ᷹ቯⵝ⟎ߩା 㗬ᕈ⏕⹺ߩߚ߼ߦ㧘߇ᬌ಴ߐࠇࠆ㧚ߘߩ⿠Ḯ෸߮⊒↢ࡔࠞ࠾࠭ࡓߩ⸃᣿ߩ

ห৻᳓Ḯ߆ࠄណขߒߚࠨࡦࡊ࡞ࠍ↪޿ߡ㧘⒳㘃ߩⵝߚ߼㧘᧲ർ࿾ᣇࠍᮮᢿߔࠆ✲ᐲ਄ߢ㒠ਅ‛ࠍណขߒߚ㧚⟎ߦࠃࠆᲧセታ㛎ࠍⴕߞߚ㧚ᶧ૕ࠪࡦ࠴࡟࡯࡚ࠪࡦࠞ

ߘߩ⚿ᨐ㧘   Cs 㒠ਅ㊂ߪᣣᧄᶏ஥࿾ၞߢ㜞޿௑ะ߇࠙ࡦ࠲ߦኻߔࠆઁߩⵝ⟎ߩ᷹ቯ୯ߣߩᲧセߢߪ㧘 IM⷗ࠄࠇߚ㧚߹ߚ㧘ችၔ⋵ߣ⑔ጟ⋵ߢᄢ᳇ᶋㆆߓࠎࠍណ

ᴰല⸘એᄖߩ⒳㘃ߩⵝ⟎㧔ࡃࡉ࡝ࡦࠣⵝ⟎㧗㔚㔌▫

ขߒߡ Cs ࠍ᷹ቯߒߚߣߎࠈ㧘 Cs Ớᐲߪᄢ㒽⿠Ḯᑼ㧘㕒㔚᝝㓸ᑼ࡜࠼ࡦࡕ࠾࠲㧕ߢߪr㧑એౝߢ޽ߞ

ࠛࠕࡠ࠱࡞㘧᧪ᤨߦ㜞޿୯ࠍ␜ߒߚ㧚ߚ㧚৻ᣇ㧘 IM ᴰല⸘ߪ⹜ᢱ A ߦߟ޿ߡ㧑㧘⹜ᢱ B㧖 ችၔ⋵ේሶജ࠮ࡦ࠲࡯

ߦߟ޿ߡߪ㧑ߩᏅ߇↢ߓߚ㧚 IM ᴰല⸘ߪ‫ޟ‬㋶ᴰಽ㧖 ጊᒻᄢቇ

ᨆᴺᜰ㊎‫ߦޠ‬ᜰቯߐࠇߡ޿ࠆಽᨆⵝ⟎ߢ޽ࠅ㧘ᓥ᧪߆







ࠄ᷷ᴰ᳓ߩಽᨆߦ↪޿ࠄࠇߡ߅ࠅ㧘ᩞᱜᣇᴺ╬ߩᬌ⸛߇ᔅⷐߢ޽ࠆ㧚㧖 ᡼኿✢කቇ✚ว⎇ⓥᚲ㧖 ␹ᚭ⮎⑼ᄢቇ
㧖 ጊ᪸ᄢቇ㧖 㚅Ꮉᄢቇ

 Bio-kinetics of radon ingested from drinking water
Tetsuo Ishikawa

㧖Shinji Tokonami

㧘 Yukinori Narazaki 㧘 Yumi Yasuoka㧖㧘 YujiYamada㧖 㔚⸃ᴺߦࠃࠆ࿾ਅ᳓ਛߩ⎣㉄ᕈ⓸⚛ߩၮ␆⊛㒰෰㧖㧦 Radiation

Protection Dosimetry㧘 㧘-㧘ࡎ ࡯࡞ࡏ࠺ࠖࠞ࠙ࡦ࠲ ࠍ↪޿ߡ࡜࠼ࡦߩ⢗߆ࠄߩ㧘ታ㛎᧻የብ㧘╣የᢕሶ㧘᳗ᷗ⟵ቁ㧘⍹ᯅⲢሶ㧘⷏Ꮉ㓷㜞 㧖㧦⑔ጟ⋵଻ஜⅣႺ⎇ⓥᚲᐕႎ㧘╙ภ㧘-㧘ᶖᄬㅦᐲࠍ⹏ଔߒߚ㧚࡜࠼ࡦࠍ㘶ᢱ᳓ߣߒߡ៨ขߒߚ

᳓ߩ㔚᳇ಽ⸃ߦࠃߞߡ↢ߕࠆᒝ㉄ᕈ㔚⸃᳓ߪᲕ⩶૞

ੑੱߩⵍ㛎⠪ߦߟ޿ߡ㧘⢗ߩ਄ߦ NaI ᬌ಴ེࠍ࿕ቯߒ

↪߇޽ࠆߎߣ߆ࠄ㧘Ვ⩶೷ߣߒߡㄘᬺಽ㊁ߢ㔚⸃ⵝ⟎ߡ᷹ቯࠍⴕߞߚ㧚 Pb ߣ Bi ߆ࠄ᡼಴ߐࠇࠆࠟࡦࡑ✢ࠍዉ౉ߔࠆ੐଀߽ߺࠄࠇࠆ㧚㔚⸃ⵝ⟎ߪේℂ⊛ߦ⎣㉄ߩ⸘ᢙ₸ࠍ៨ขᓟߩᤨ㑆ߣߣ߽ߦ⸥㍳ߒߚ㧚࡜࠼ࡦ෸ᕈ⓸⚛߽Ớ❗㨯ಽ㔌ߢ߈ࠆߣ⠨߃ࠄࠇ㧘⇌࿾๟ㄝߩ⎣





߮ߘߩሶቊᩭ⒳ߦ㑐ߔࠆ૕ౝേᘒࠍ⴫⃻ߒߚࠦࡦࡄ࡯

㉄ᕈ⓸⚛ᳪᨴ੗ᚭ᳓߆ࠄ⓸⚛ᚑಽࠍ㒰෰ߒ㧘⢈ᢱߣߒ࠻ࡔࡦ࠻ࡕ࠺࡞ࠍ↪޿ߡ㧘ߎࠇࠄߩ⸘ᢙ₸࠺࡯࠲ߩ⸃

ߡౣ೑↪ߔࠆߎߣ߇น⢻ߣߥࠆ㧚ၮ␆⊛ታ㛎ࠍⴕ߁ߚᨆࠍⴕߞߚ㧚ߔߥࠊߜ㧘ࡕ࠺࡞߇ታ㛎࠺࡯࠲ߦࡈࠖ࠶

߼㧘㔚⸃ᮏߩಽ㔌⤑ߦᄙሹ⾰⤑ࠍ↪޿㧘㔚ᭂߪ࠴࠲ࡦ

࠹ࠖࡦࠣߔࠆࠃ߁ߦ㧘⢗߆ࠄߩ࡜࠼ࡦߩᶖᄬㅦᐲߥߤ

᧼ߦ⊕㊄ࠍࠦ࡯࠹ࠖࡦࠣߒߚ㔚⸃ⵝ⟎ࠍ⹜૞ߒߚ㧚ߩࡄ࡜ࡔ࡯࠲ࠍᄌൻߐߖߚ㧚ᓥ᧪㧘࡜࠼ࡦߩ⢗߆ࠄߩ

 mg/l ߩ ⎣㉄ᕈ⓸⚛ߢᳪᨴߐࠇߚ࿾ਅ᳓ࠍ⹜ᢱߣߒ

ឃ಴ߪ᳓ߩឃ಴ㅦᐲߣห╬ߢ޽ࠆߣ⠨߃ࠄࠇߡ߅ࠅ㧘ߡ↪޿㧘㔚⸃ⵝ⟎ߩ㔚ᭂߦශട㔚࿶́V ߢᤨ㑆ㅢ⢗߆ࠄߩឃ಴ߦ㑐ߔࠆඨᷫᦼߪಽߣ޿߁ߩ߇ౖဳ⊛㔚ߒ㧘⎣㉄ᕈ⓸⚛ߩಽ㔌㨯Ớ❗ߦ㑐ߔࠆᬌ⸛ࠍⴕߞߚ㧚ߥ୯ߢ޽ࠆ㧚ߒ߆ߒߥ߇ࠄᧄ⎇ⓥߢߪ㧘એ೨ߩࡕ࠺࡞

ߘߩ⚿ᨐ㧘ශട㔚࿶ V㧘ᤨ㑆ߩㅢ㔚ߢ㧘㒶ᭂᮏߩߢ⠨߃ࠄࠇߡ޿ߚࠃࠅ߽㐳ߊ⢗ߩਛߦ⇐߹ߞߡ޿ࠆߎ

⎣㉄ᕈ⓸⚛Ớᐲߪmg/l ߹ߢᷫዋߒ㓁ᭂᮏߢ pH㧘ߣ߇␜ໂߐࠇߚ㧚⎣㉄ᕈ⓸⚛ mg/l ߩ ᒝ㉄ᕈỚ❗᳓߇ᓧࠄࠇߚ㧚㔚⸃㧖 National Institute of Radiological Sciencesⵝ⟎ߦࠃࠆ⎣㉄ᕈ⓸⚛ߩಽ㔌㨯Ớ❗߇น⢻ߢ޽ࠆߎߣ

㧖 Kobe Pharmaceutical University߇ࠊ߆ߞߚ㧚㧖 ⁛┙ⴕ᡽ᴺੱ࿖┙ⅣႺ⎇ⓥᚲ 㔚᳇ㅘᨆⵝ⟎ߣ↢‛⣕⓸ⵝ⟎ߦࠃࠆ⎣㉄ᕈ⓸⚛ᳪ The mutagenicity of amino-derivatives of diphenylᨴ࿾ਅ᳓ߩࠝࡦࠨࠗ࠻ᵺൻ

ether herbicides in new Salmonella typhimurium YG㚍႐⟵ノ㧘᧻የብ㧘⍹ᯅⲢሶ㧘᳗ᷗ⟵ቁ㧘㜞ᯅᵗሶ㧘tester strains㊁ਛା৻㧘ᐔ ↰ஜᱜ 㧘⷏Ꮉ㓷㜞㧦᳓ⅣႺ ቇળ⹹㧘

Yoshito 㧘㨺㧘㧚Nobuyuki Sera and Shigeji Kitamori 㧦 Water Science and⎣㉄ᕈ⓸⚛ᳪᨴ࿾ၞߢᵺൻࠪࠬ࠹ࡓࠍࡩ᦬㑆ㆇォ

Technology㧘 - 㧘 -㧘

Tanaka Nobuhiro Shimizu Hiroko Tsukataniߒ㧘ߘߩ⓸⚛㒰෰ലᨐ෸߮๟ㄝⅣႺ߳ߩᓇ㗀ࠍ⺞ߴࠆ㧠⒳ߩࠫࡈࠚ࠾࡞ࠛ࡯࠹࡞♽㒰⨲೷ߣⅣႺਛߢߩಽ⸃

ታ⸽⹜㛎ࠍታᣉߒߚ㧚ᵺൻࠪࠬ࠹ࡓߪ㔚᳇ㅘᨆⵝ⟎ߣ

ㆊ⒟ߢ↢ߓࠆࠕࡒࡁ⺃ዉ૕ߩᄌ⇣ේᕈࠍᓥ᧪ߩ

↢‛⣕⓸ⵝ⟎߆ࠄ᭴ᚑߐࠇ㧘ᐕ㑆ߩᵺൻࠪࠬ࠹ࡓߩ

Salmonella typhimurium TA ᩣ ߣᣂߚߦ㐿⊒ߐࠇߚ YG

ㆇォߦࠃࠅ㧘⹜㛎࿾ߦ߅޿ߡ kg ߩ⓸⚛߇࿾ਅ᳓߆

ᩣࠍ↪޿ߡ᷹ቯߒߚ㧚੹࿁૶↪ߒߚ YG ᩣߪ࠾࠻ࡠࠕ

ࠄ㒰෰ߐࠇߚ㧚࡟࡯ࡦ㘃߿ࡅ࠼ࡠࠠࠪࠕࡒࡦߩᄌ ⇣ ේ ᕈ ࠍ 㜞 ᗵ ᐲ ߦ⓸⚛㒰෰ലᨐࠍ⹏ଔߔࠆߚ߼ߦ⹜㛎࿾ၞߩ⓸⚛෼ᡰᬌ಴ߔࠆߚ߼ߦ 㐿⊒ ߐ ࠇ ߚᩣߣ㉄ൻဳᄌ⇣ේ߿ࠕ࡞෸߮᳓෼ᡰࠍ⸘▚ߒߚ⚿ᨐ㧘⹜㛎࿾ߦ߅ߌࠆ㧝ᐕ㑆ߩࠠ࡞ൻ೷ߦㆬᛯ⊛ߦᬌ಴ߔࠆᩣࠍ↪޿ߚ㧚ߘߩ⚿ᨐ㧘⓸⚛ᚑಽߩ࿾ਅᶐㅘ㊂ߪkg ߣߥࠅ㧘ᵺൻࠪࠬ࠹ࡓ

YG ᩣߢߪᓥ᧪ߩ TA ᩣࠃࠅ㜞ᗵᐲߦᄌ⇣ේᕈ߇ᬌ಴

ߦࠃࠅ⹜㛎࿾ߩ࿾ਅᶐㅘ⓸⚛㊂ߩ %߇㒰෰ߐࠇߚߐࠇࠆߎߣ߇᣿ࠄ߆ߦߥࠅ㧘ߘߩ᦭↪ᕈ߇␜ໂߐࠇߚ㧚ߣ⹏ଔߐࠇߚ㧚߹ߚ㧘ࠫࡈࠚ࠾࡞ࠛ࡯࠹࡞♽㒰⨲೷ߪේ૕ࠃࠅࠕࡒࡁ

ᵺൻࠪࠬ࠹ࡓߩㆇォߦࠃࠅಣℂ᳓ߩ᡼ᵹవߩḳᳰߩ૕ߩᣇ߇ᄌ⇣ේᕈ߇㜞޿ߎߣ෸߮᳓ਛߢߪᓸ↢‛ಽ⸃ንᩕ㙃ൻߦߟ޿ߡ⺞ᩏߒߚߣߎࠈ㧘ḳᳰ᳓⾰߳ߩᓇ㗀ߦࠃࠅኈᤃߦࠕࡒࡁ૕ߦㆶరಽ⸃ߐࠇࠆߎߣࠍታ㛎⊛ߪዋߥ޿ߣផቯߐࠇߚ㧚ߦ᣿ࠄ߆ߦߒߚ㧚 ⑔ጟ⋵ߦ߅ߌࠆᨋ࿾߆ࠄߩ$1&㧘%1&㧘ో⓸⚛෸߮

 Estimation of orgnophosphoric acid triesters in softో࡝ࡦߩᵹ಴⽶⩄

polyurethane foam using a concentrated sulfuric acid᳗ᷗ⟵ቁ㧘᧻የብ㧘૒‫ᧁޘ‬㊀ⴕ 㧦⑔ጟ⋵଻ஜⅣႺ⎇

dissolution technique and gas chromatography with flameⓥᚲᐕႎ㧘╙ภ㧘-㧘

photometric detection㧖⑔ጟ⋵ᷝ↰↸ߩ⋵༡ᨋౝ߆ࠄᵹ಴ߔࠆᷧᵹ᳓ߩ᳓⾰

Makoto Nagase㧘 Mineki Toba㧘 Hiroyuki Kondo㧘 Akio෸߮ߘߩᵹ಴⽶⩄ߦߟ޿ߡᐕ߆ࠄᐕߩᐕ㑆

Yasuhara 㧖 㧘 and Kiyoshi Hasebe 㧖 㧦 Analytical Sciences㧘ߦࠊߚࠅᬌ⸛ߒߚ㧚⺞ᩏኻ⽎ߣߒߚᵹၞ㧔 W-㧘 W-  㧘-㧘

෸߮ E-㧕ߦ߅ߌࠆ BOD ߩᐔဋỚᐲߪ㧘ᴡᎹߩⅣႺ

⎫㉄ṁ⸃ᴺ෸߮ࠟࠬࠢࡠࡑ࠻ࠣ࡜ࡈࠖ࡯ࠍ↪޿ၮḰ AA 㘃ဳ㧔 mg/l㧕ࠍ޿ߕࠇ߽ਅ࿁ߞߡ޿ߚ㧚ߚ㧘エ⾰ࡐ࡝࠙࡟࠲ࡦࡈࠜ࡯ࡓਛߩ᦭ᯏ࡝ࡦ㉄࠻ᵹၞߩᷧᵹ᳓ߣ߽ BOD ߣ COD ߣߩ㑆ߦߪ⋧㑐ߪߥ࡝ࠛࠬ࠹࡞㘃㨧࡝ࡦ㉄࠻࡝ࡉ࠴࡞㧘࡝ࡦ㉄࠻࡝ࠬ߆ߞߚ㧚⺞ᩏ⚿ᨐ߆ࠄ▚಴ߒߚᵹၞߦ߅ߌࠆ BOD ߩ -ࠢ ࡠ ࡠ ࠛ ࠴ ࡞ 㧘 ࡝ ࡦ ㉄ ࠻ ࡝ ࠬ  -ࠢ ࡠ ࡠ ࡊ ࡠ ࡇᐕ 㑆 ᐔ ဋ ᵹ ಴ ⽶ ⩄ ㊂ ߪ 㧘    -   kg/ha࡮ ᐕ ߢ ޽ ࠅ㧘࡞ 㧘 ࡝ ࡦ ㉄ ࠻ ࡝ ࠬ  - ࠫ ࠢ ࡠ ࡠ -  - ࡊ ࡠ ࡇ ࡞ 㧘 ࡝

COD ߪ-kg/ha࡮ᐕߢ޽ߞߚ㧚৻ᣇ㧘 T-N ߪ

ࡦ㉄࠻࡝ࡈࠚ࠾࡞෸߮࡝ࡦ㉄࠻࡝ࠬ ࡉ࠻ࠠࠪࠛ࠴

 -kg/ha࡮ᐕߢ޽ࠅ㧘 T-P ߪ-kg/ha࡮ᐕߢ࡞ 㨩ߩಽᨆᴺࠍ㐿⊒ߒߚ㧚ߎߩಽᨆᴺߩᬌ಴㒢⇇޽ߞߚ㧚ߎࠇࠄߩᢙ୯ߪ㧘㒠ਅ‛߆ࠄଏ⛎ߐࠇࠆ⽶⩄ߪ - Ǵg/g ߢ޽ ࠅ㧘ታ⹜ᢱ߆ࠄ⒳ߩ ᦭ᯏ ࡝ࡦ㉄㊂ߣᲧセߒߡ㧘߶߷ห⒟ᐲ߆ߘࠇࠃࠅૐ޿ߣផቯߐࠇ

࠻࡝ࠛࠬ࠹ ࡞㘃߇ ND- Ǵg/g ᬌ಴ߐࠇߚ㧚ߚ㧚㧖 National Institute for Environmental Studies㧖 ⑔ጟ⋵᫪ᨋᨋᬺᛛⴚ࠮ࡦ࠲࡯

㧖 Fuji Women's University ⑔ጟ⋵ౝዊᴡᎹߩᄢဳᐩ↢േ‛⋧ ਛ࡮ዊဳߩ᳓↢ࠞࡔࡓࠪ⋡ࠍ↪޿ߚ↢ᘒᓇ㗀⹏ଔጊፒᱜᢅ㧘✜ᣇஜ㧘᧖ᵏᤘ㧦⑔ጟ⋵଻ஜⅣႺ⎇ⓥᚲᐕ⹜㛎ႎ㧘╙ภ㧘-㧘

✜ᣇஜ㧦ᣣᧄⅣႺᲥᕈቇળ㧔✬㧕㧘↢ᘒᓇ㗀⹜㛎ࡂࡦ⑔ጟ⋵ౝߩዊᴡᎹߩᄢဳᐩ↢േ‛ߩ↢ᕷ⁁ᴫࠍ⺞࠼ࡉ࠶ࠢ㧘ᦺୖᦠᐫ㧘 pp-㧘

ᩏߒߚ㧚⺞ᩏߪ࿾ὐߢⴕߞߚ߇㧘ߎࠇࠄߩ߁ߜ࿾

ൻቇ‛⾰ߩ᳓↢᣸⯻ߦኻߔࠆ↢ᘒᓇ㗀⹏ଔ⹜㛎ߩኻὐߪ㧘ఝභ⒳෸߮ఝභ⒳એᄖߣ߽㧘ᳪỘߒߚ᳓ၞ߿㧘⽎↢‛ߣߒߡߩ᳓↢ࠞࡔࡓࠪ⋡ߩ㘺⢒ᴺ࡮⹜㛎ᴺߦߟ

߿߿ᳪỘߒߚ᳓ၞߦ↢ᕷߔࠆ⒳㘃ߢ޽ࠅ㧘 ASPT ୯߽޿ߡ⸃⺑ߒߚ㧚૶↪ߒߚ↢‛ߪ㧘࠽ࡌࡉ࠲ࡓࠪ㧘ࠕࠨૐ߆ߞߚ㧚ߎࠇࠄએᄖߦ࿾ὐߢߪ㧘߿߿ᳪỘߒߚ᳓ၞࡅ࠽ࠦࡒ࠭ࡓࠪ㧘ࡑ࡞ࡒ࠭ࡓࠪߩ⒳ߢ㧘ߘࠇߙࠇ㧘߿ ᷡ ᶭ ߥ ᳓ ၞ ߦ ↢ᕷ ߒ ߡ ޿ ࠆ ⒳ 㘃 ߇ ᷙ ࿷ ߒߡ߅ ࠅ㧘࡙ࠬ࡝ࠞᐜ⯻㧘ੇ῎㉂Უ㧗⮺㘃㧘ࠝࠝࡒࠫࡦࠦࠍ㙄ߣ

ASPT ୯ߦࠃࠆ⹏ଔߢ߽ᭂ┵ߦਇ⦟ߥ᳓ⅣႺߪߥߊ㧘ߔࠆߎߣߢ⚥ઍ㘺⢒߇น⢻ߢ޽ߞߚ㧚Ქᕈ⹜㛎ߩᣇᴺ߿߿⦟ᅢߥ᳓ⅣႺ߆ࠄ⦟ᅢߥ᳓ⅣႺߣ޿߃㧘੹ᓟ㧘᳓ߪࠝ ࠝ ࡒࠫ ࡦ ࠦ ࠍ↪ ޿ ߚ ᕆ ᕈ Ქ ᕈ ⹜ 㛎 ᣇᴺ ߣห ᭽ߦ⾰ߩᡷༀ߿๟ㄝⅣႺߩᡷༀ߇ㅴ߼߫㧘ᷡᶭߥ᳓ၞߦ↢ ml ࡆ࡯ࠞ࡯ࠍ↪޿ߚᣇᴺߢน⢻ߢ޽ߞߚ߇㧘࠽ࡌ

ᕷߔࠆ⒳㘃߇Ⴧടߒ㧘↢‛ቇ⊛ߦ⦟ᅢߥⅣႺߦߥߞߡ

ࡉ࠲ࡓࠪߦߟ޿ߡߪੱญᐩ⾰ߣߒߡዊဳࠟ࡜ࠬ₹ࠍᢙ޿ߊ߽ߩߣᕁࠊࠇߚ㧚߹ߚ㧘⛘Ṍෂᗋ⒳߿․ᱶߥⅣႺ୘㧘ࠕࠨࡅ࠽ࠦࡒ࠭ࡓࠪߣࡑ࡞ࡒ࠭ࡓࠪߦߟ޿ߡߪ᳓

ߦ↢ᕷߔࠆᏗዋ⒳㧘ᧂ⸥㍳⒳߽↢ᕷߒߡ߅ࠅ㧘ᴡᎹ᳓⨲ߩઍࠊࠅߦ࠹ࡈࡠࡦࡀ࠶࠻ࠍ౉ࠇߡ߿ࠆߎߣߢⴕേ

ⅣႺߩ଻ోߪᴡᎹᧄ✢ߩߺߢߪߥߊዊᴡᎹߩ଻ో߽㊀߇቟ቯߒࠃࠅ⦟ᅢߥ⚿ᨐ߇ᓧࠄࠇߚ㧚ⷐߣᕁࠊࠇߚ㧚 ⑔ጟ⋵ਅߩᴡᎹḮᵹㇱߩᄢဳᐩ↢േ‛⋧✜ᣇஜ㧘᧖ᵏᤘ㧘ጊፒᱜᢅ㧦⑔ጟ⋵଻ஜⅣႺ⎇ⓥᚲᐕႎ㧘╙ภ㧘-㧘
⑔ጟ⋵ਅߩᴡᎹḮᵹㇱߩᄢဳᐩ↢േ‛⋧ࠍ⺞ߴߚ㧚ਥⷐߥ↢‛⟲ߩ߁ߜࠞࠥࡠ࠙⋡㧘ࠞࡢࠥ࡜⋡ߩ୘૕ᢙߩᏅߪߪᴡᎹḮᵹㇱ๟࿐ߩᣣ኿㊂ߩᓇ㗀߇ᄢ߈޿ࠃ߁
ߦᕁࠊࠇߚ㧚߹ߚ㧘ઁߩḮᵹㇱߣᲧߴߡฎಣጊḮᵹㇱߦ߅޿ߡ↲Ზ㘃෸߮⽴㘃߇․ߦᄙ߆ߞߚߩߪ㧘⍹Ἧጤߩ࿾ጀߣ㑐ㅪ߇޽ࠆ߽ߩߣᕁࠊࠇߚ㧚⑔ጟ⋵ਅߩᴡᎹḮᵹㇱߦ↢ᕷߔࠆᄢဳᐩ↢േ‛ߩ↢ᕷ⁁ᴫ߆ࠄߪ㉄ᕈ㒠ਅ‛ߩᓇ㗀ࠍ␜ໂߔࠆࠃ߁ߥ⚿ᨐߪᓧࠄࠇߥ߆ߞߚ㧚ߒ߆ߒ㧘ᴡᎹḮᵹㇱߩ↢‛⋧ߪ᷷ᥦൻ╬ߩ࿾⃿ⷙᮨߩ
ⅣႺᄌേߩᓇ㗀ࠍฃߌ߿ߔ޿߽ߩߣᕁࠊࠇ㧘੹ᓟ߽ቯᦼ⊛ߥࡕ࠾࠲࡝ࡦࠣ⺞ᩏ߇ᦸ߹ࠇࠆ㧚㧔㧟㧕ቇળ╬ญ㗡⊒⴫৻ⷩ
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Deposition of atomospheric dioxins Yoichi Kurokawa Okihiro Ohishi Kazuhiroቇળฬ㧔႐ᚲ㧕㧘ᐕ᦬ᣣ
23rd International Symposium on

to the surrogate surfaces to elucidate Tobiishi Nobuaki Soh and Toshihiko Imato

Halogenated Environmental Organic

the uptake pathway by plant leaves

pollutants and POPs (Boston, USA),and the application of a surrogate

August 24-29, 2003.

surface to long term monitoring
Thermo-desorption

analysisof

Takahiko Matsueda,Yoshifumi Hanada 㧖, Yuan

23rd International Symposium on

Yao 㧖, Teiji Tanizaki 㧖, Takeshi Kuroiwa 㧖, Halogenated Environmental Organic

dioxins and related compounds

Makoto Moriguchi 㧖 and Kazuhiro Tobiishi

pollutants and POPs (Boston, USA),㧖 Kitakyusyu City Institute ofAugust 24-29, 2003.

Environmental Sciences㧖 Kyushu Techno Research INC.
㧖 BC Techno Research Kyusyu Co.
Improvement of solvent cut large
volumeSCLV

Kazuhiro Tobiishi Tsuguhide Hori Yasuhisa

injection system Ishiguro and Takao Iida

23rd International Symposium on
Halogenated Environmental Organic

using narrow-bore column in dioxins

pollutants and POPs (Boston, USA),

analysis by HRGC-HRMS

August 24-29, 2003.

Structure

relationship Nobuyuki Sera Kiyoshi Fukuhara 㧖 Naoki 19th International symposium on

activity

Miyata 㧖 Hiroshi Tokiwa 㧖 Shigeki Sasaki 㧖between chemical properties and
8-hydroxyguanine

formation

nitrophenanthrenes and their related 㧖 National Institute of Health Sciencescompounds

in

the

fresh

polycyclicaromatic hydrocarbons-exposure health effects and riskof and Hideo Utsumi 㧖
rat 㧖 Nagoya City University

assessment-

Netherland 

September 21-25, 2003.

㧖 Kyushu Women's University

hepatocytes㧖 Kyushu University
Study Regarding the Technique to Takaaki Shimohara 㧘Hisao Chikara  Naruyasu JSPS-MOE‫ޟ‬ㇺᏒⅣႺ‫ޠ‬ቇⴚ੤ᵹ
ReduceToxic

A t m o s p h e r i c Itagaki Masuski Shirahama 㧖㧘Takashi Enjoji ࿖㓙࠮ࡒ࠽࡯㧘ਛ࿖㧔਄ᶏᏒ 㧕㧘

Substances ̆ Technique to Remove 㧖 and Isao Mochida 㧖
Nitrogen

Oxidesby

Activated 㧖 Kyushu University

Carbon Fibers ̆
Scavenging

ᐔᚑᐕ᦬㧙ᣣ ᜗ᓙ㧘⻠Ṷ㧖 Industrial Technology Center of SAGA

technology

of

air Takaaki Shimohara㧘Hisao Chikara Naruyasu The

NinthInternational

Joint

pollutants using activated carbon Itagaki Masuski Shirahama 㧖㧘Takashi Enjoji Seminar on the Regional Deposition
fiber and its prospect for the future㧖and Isao Mochida 㧖Processes

㧖 Kyushu University

in

the

Atmospere㧘Bangkok Thailand㧘Dec 1-4. 2003.

㧖 Industrial Technology Center of SAGA
Realt i m ec o n t i n u o u s Naruyasu

Itagaki Hisao

Chikara Takaaki The

NinthInternational

Joint

determination of NOx concentration ShimoharaTakashi Enjoji 㧖and Isao Mochida 㧖 Seminar on the Regional Deposition
in atmospheric environments⸘㧔࿖㓙ቇળ㧕

㧖 Industrial Technology Center of SAGA

Processes

㧖 Kyushu University

Bangkok Thailand㧘Dec 1-4. 2003.

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ጟᕶ৻㇢

ቇળฬ㧔႐ᚲ㧕㧘ᐕ᦬ᣣᐔᚑᐕᐲో࿖ᴤ∝⎇ⓥ⃰ળ⼏ᐲో࿖㓸⸘⚿ᨐႎ๔㧔⑔ጟᏒ㧕㧘ᐔᚑᐕ᦬ᣣ

౒㡆ེ᭴ㅧࠍ᦭ߔࠆ㒐㖸ოߦ ᧻ᧄḮ↢㧘⮮ේᕶม㧖ᣣᧄ㖸㗀ቇળ㧔ฬฎደᏒ㧕㧘ࠃࠆૐ๟ᵄ㖸ߩ೙ᓮᐔᚑᐕ᦬ᣣ

㧖਻Ꮊᄢቇ౒㡆ེ᭴ㅧࠍ᦭ߔࠆ㒐㖸ოߦ ᧻ᧄḮ↢㧘⮮ේᕶม㧖ᣣᧄ㖸㗀ቇળ㧔ෘᧁᏒ㧕㧘ࠃࠆૐ๟ᵄ㖸ߩ೙ᓮ ߘߩᐔᚑᐕ᦬ᣣ

㧖਻Ꮊᄢቇᄢ᳇ਛ࠳ࠗࠝࠠࠪࡦ㘃ߩ TEQ ᧻ᨑ㓉ᒾ㧘㤥Ꮉ㓁৻㧘ᄢ㊁ஜᴦ㧘㘧⍹๺ᄢ㧘㚍႐ ╙࿁ⅣႺൻቇ⸛⺰ળ㧔ᣂẟᏒ㧕㧘ᜰᮡ⇣ᕈ૕ߩᬌ⚝ߣ◲ᤃಽᨆ ⟵ノ㧘⍹㤥㕏ዏᐔᚑᐕ᦬㧙ᣣ߳ߩᔕ↪
ᬌ૕ߩ㘩ຠᱷຠ߆ࠄ㧻߇ ၳᎹ๺⟤㧘㐳㊁⧷ବ㧘ựፒశብ㧘᧛਄శ৻㧘㜞 ╙࿁⣺▤಴ⴊᕈᄢ⣺⩶ᗵᨴ∝ࠪಽ㔌ߐࠇߚ㘩ਛᲥ੐଀ߦߟ޿ ↰ᥓ㧘᪢ፒ⺈ᴦ㧘㜞↰ೣሶ㧖㧘ᄙ↰ବഥ㧖ࡦࡐࠫ࠙ࡓ ᧲੩㧕㧘ᐔᚑᐕ᦬ߡᣣ㧖 ↢ᵴⴡ↢⺖㧘㧖 ཅⓄ଻ஜ⑔␩ⅣႺ੐ോᚲ࠙ࠚ࡞ࠪࡘ⩶ࠍේ࿃ߣߔࠆ㘩 ựፒశብ㧘᧛਄శ৻㧘㐳㊁⧷ବ㧘ၳᎹ๺⟤㧘㜞↰ ╙࿁ᣣᧄ౏ⴐⴡ↢ቇળ㧔੩ㇺ㧕㧘ਛᲥ੐଀ߦߟ޿ߡ

ᥓᐔᚑᐕ᦬ᣣ

㉄ൻᴤ⢽៨ขߦࠃࠆ⢄ߩ⣲≌ Ꮢἑቁ㆏㧖㧘㜞㊁␭ਭ㧖㧘ቯ㊄㚅㉿㧖㧘਎⦟ᥰਯ㧘⧯ ╙࿁ᣣᧄ≸ቇળ✚ળ㧔ฬฎደ⊒↢ߣ㉄ൻ⊛ DNA ்ኂᨋᢘੑ㧖㧘⿥⍮ብ୶㧖㧘ᩊᧄ㜞ⴕ㧖Ꮢ㧕㧘ᐔᚑᐕ᦬ᣣ㧖 ᄢಽ⋵┙⋴⼔⑼ቇᄢቇ㧘㧖 ੩ㇺᐭ┙ක⑼ᄢ
ቇ㧘㧖 ࿖┙߇ࠎ࠮ࡦ࠲࡯㧘㧖 ᣣᧄ⠧ൻ೙ᓮ⎇ⓥᚲ㧘㧖 ࠞ࡝ࡈࠜ࡞࠾ࠕᄢቇ
㉄ൻᴤ⢽៨ขߦࠃࠆ⢄⚵❱ߩ ቯ㊄㚅㉿㧖㧘Ꮢἑቁ㆏㧖㧘㜞㊁␭ਭ 㧖㧘਎⦟ᥰਯ㧘 ╙࿁ᣣᧄ≸ቇળ✚ળ㧔ฬฎደ㉄ൻ⊛ DNA ்ኂߣୃᓳ㉂⚛ ⧯ᨋᢘੑ㧖㧘⿥⍮ብ୶㧖㧘ᩊᧄ㜞ⴕ㧖m-RNA ⊒⃻ߩࡑ࠙ࠬ♽⛔ᏅᏒ㧕㧘ᐔᚑᐕ᦬ᣣ

㧔ᚲዻߪ೨㗄ߣหߓ㧕࠾࠻ࡠࡈࠚ࠽ࡦࠬ࡟ࡦ෸߮࠾ ਎⦟ᥰਯ㧘⑔ේẖ㧖㧘Ᏹ⋚ኡ㧖㧘ౝᶏ⧷㓶㧖㧘૒‫ ޘ‬ᣣᧄⅣႺᄌ⇣ේቇળ╙࿁ᄢળ
࠻ࡠࠕࠩࡈࠚ࠽ࡦࠬ࡟ࡦߩ‛ ᧁ⨃ᧁ㧖㧘ች↰⋥᮸㧖㧔ᵤᏒ㧕㧘ᐔᚑᐕ᦬ᣣ

ℂൻቇ⊛ᕈ⁁ߣᄌ⇣ේᕈ㧘 㧖 ࿖┙ක⮎ຠ㘩ຠⴡ↢⎇ⓥᚲ㧘㧖 ਻Ꮊᅚሶᄢ
-oxo-Gua ↢ᚑ⢻ߣߩ᭴ㅧᵴᕈ ቇ㧘㧖 ਻Ꮊᄢቇ㧘㧖 ฬฎደᏒ┙ᄢቇ⋧㑐ߦߟ޿ߡ
DNA ៊்ࠍᛥ೙ߔࠆᚑಽߩᬌ ਎⦟ᥰਯ㧘⑔ේẖ㧖㧘૒‫ᧁ⨃ᧁޘ‬㧖㧘ౝᶏ⧷㓶㧖㧘 ╙࿁ᄢ᳇ⅣႺቇળ਻Ꮊᡰㇱ⎇ⓥ⚝෸߮ᔕ↪㧙ᄢ᳇ᶋㆆ☳Ⴒ෸ Ᏹ⋚ኡ㧖㧘ች↰⋥᮸㧖㧘⧯ᨋᢘੑ㧖⊒⴫ળ෸߮╙࿁਻Ꮊᡰㇱ✚ળ߮ࠗࡦࡈ࡞ࠛࡦࠩ࠙ࠗ࡞ࠬࠍ 㧖 ࿖┙ක⮎ຠ㘩ຠⴡ↢⎇ⓥᚲ㧘㧖 ਻Ꮊᄢቇ㧘 㧔⑔ጟᏒ 㧕㧘ᐔᚑᐕ᦬ᣣ↪޿ߡ㧙㧖 ਻Ꮊᅚሶᄢቇ㧘㧖 ฬฎደᏒ┙ᄢቇ㧘㧖 ࿖┙߇ࠎ࠮ࡦ࠲࡯

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ቇળฬ㧔႐ᚲ㧕㧘ᐕ᦬ᣣേ‛ታ㛎ߦ↪޿ߚ㤛⍾⹜ᢱߩ ⷏Ꮉ㓷㜞㧖㧘Ꮢἑቁ㆏㧖㧘᫪⢒ሶ㧖㧘ᩉᴛ೑ᨑ㧖㧘 ╙࿁ᄢ᳇ⅣႺቇળ㧔੩ㇺᏒ㧕㧘․ᓽ㜞㊁␭ਭ㧖㧘਎⦟ᥰਯ㧘ቯ㊄㚅㉿㧖㧘ᣣศቁሶ㧖㧘 ᐔᚑᐕ᦬ᣣ
㊄ᶈ㧖㧘⮍ᣩノ㧖㧘⧯ᨋᢘੑ㧖㧖 ࿖┙ⅣႺ⎇ⓥᚲ㧘㧖 ᄢಽ⋵┙⋴⼔⑼ቇᄢቇ㧘㧖 ╳ᵄᄢቇ㧘㧖 ᄢಽක⑼ᄢቇ㧘㧖 ਛᣣ෹ᅢⅣ଻ਛᔃ㧘㧖 ࿖┙߇ࠎ࠮ࡦ࠲࡯

㤛⍾ߩ⢖ᲥᕈΤ⢖⢩ᵞᵺᶧਛ ቯ㊄㚅㉿㧖㧘਎⦟ᥰਯ㧘Ꮢἑቁ㆏㧖㧘㜞㊁␭ਭ㧖㧘 ╙࿁ᄢ᳇ⅣႺቇળ㧔੩ㇺᏒ㧕㧘ߩἻ∝⚦⢩ߩᄌൻߣ -OH-Gua ⷏Ꮉ㓷㜞 㧖 㧘᫪⢒ሶ 㧖㧘ศ↰ᚑ৻㧖㧘ᩉᴛ೑ᨑ㧖㧘 ᐔᚑᐕ᦬ᣣ
ߩᒻᚑᣣศቁሶ㧖㧘Ꮉ㉿ᶈ᣿㧖㧘቟↰ᗲሶ㧖㧘㊄ᶈ㧖㧘⮍ᣩノ㧖㧘⧯ᨋᢘੑ㧖 㧔ᚲዻߪ೨㗄ߣหߓ㧕㤛⍾ߩ⢖ᲥᕈΣ⢖ߩ∛ℂߣ⢖ Ꮢἑቁ㆏㧖㧘⷏Ꮉ㓷㜞㧖㧘㜞㊁␭ਭ 㧖㧘਎⦟ᥰਯ㧘 ╙࿁ᄢ᳇ⅣႺቇળ㧔੩ㇺᏒ㧕㧘
⢩ᵞᵺᶧਛߩἻ∝⚦⢩ߩᄌൻ

ቯ㊄㚅㉿ 㧖 㧘᫪⢒ሶ 㧖㧘ศ↰ᚑ৻㧖㧘ᩉᴛ೑ᨑ㧖㧘 ᐔᚑᐕ᦬ᣣ
ᣣศቁሶ 㧖㧘Ꮉ㉿ᶈ᣿㧖㧘቟↰ᗲሶ 㧖㧘㊄ᶈ㧖㧘⮍ᣩノ㧖㧘⧯ᨋᢘੑ㧖HIV ߩ⮎೷⠴ᕈ㧔ᚲዻߪ೨㗄ߣหߓ㧕ජ‫ޘ‬๺ൎᏆ㧘ᳯ⮮⦟᮸ⴡ↢ᓸ↢‛ᛛⴚද⼏ળ╙࿁⎇ⓥળ ⑔ጟᏒ 㧘ᐔᚑᐕ᦬ᣣߔࠅりടᎿᛛⴚߦࠃࠆ㝼⡺ਛ ᄢፉ㓶ᴦ㧖㧘૒ષብ᮸㧖㧘ၳዞ⧷㧘ᧄၔಠᄦ㧖╙࿁ⅣႺൻቇ⸛⺰ળ㧔ᣂẟᏒ㧕㧘

PCBs ߩ೥ᷫ

ᐔᚑᐕ᦬㧙ᣣ㧖 ਻Ꮊᄢቇ㧘㧖 ർᶏ㆏ᄢቇ

㜞ᵴᕈ὇⚛❫⛽ࠍ↪޿ߚⅣႺ ജኼ㓶㧘ਅේቁ┨㧘౞ၔኹ㓉ᔒ㧖╙࿁ᄢ᳇ⅣႺቇળᐕળ㧔੩ㇺᄢ᳇ᵺൻߦ㑐ߔࠆ⎇ⓥ Ꮢ㧕㧘ᐔᚑᐕ᦬㧙ᣣ㧙 㧖 ૒⾐⋵Ꮏᬺ࠮ࡦ࠲࡯

NO ߩ㉄ൻ෻ᔕ㧘HNOߣߒߡߩ࿁෼㧙㜞ᵴᕈ὇⚛❫⛽ࠍ↪޿ߚⅣႺ ജኼ㓶㧘ਅේቁ┨㧘౞ၔኹ㓉ᔒ㧖㧘ᜬ↰ൟ㧖ᄢ᳇ᵺൻߦ㑐ߔࠆ⎇ⓥ㧙⓸ 㧖 ૒⾐⋵Ꮏᬺ࠮ࡦ࠲࡯㧘㧖 ਻Ꮊᄢቇ⚛㉄ൻ‛ߩๆ⌕෸߮㉄ൻ࡮ㆶ╙࿁ⅣႺ଻ో㨯౏ኂ㒐ᱛ⎇ⓥ⊒
⴫ળ㧔ᓼፉᏒ㧕㧘ᐔᚑᐕ᦬㧙ᣣర෻ᔕ㧙㜞ᵴᕈ὇⚛❫⛽ࠍ↪޿ߚⅣႺ ਅේቁ┨㧘ജኼ㓶㧘౞ၔኹ㓉ᔒ㧖╙࿁ᄢ᳇ⅣႺቇળᐕળ㧔੩ㇺᄢ᳇ᵺൻߦ㑐ߔࠆ⎇ⓥ Ꮢ㧕㧘ᐔᚑᐕ᦬㧙ᣣ㧙 㧖 ૒⾐⋵Ꮏᬺ࠮ࡦ࠲࡯

ㆶర೷ࠍ↪޿ߚ NOx ߩㆶర㧘ήኂൻߩ⹜ߺ㧙਻Ꮊർㇱ࿾ၞߦ߅ߌࠆᤐᦼߩ ਅේቁ┨㧘ജኼ㓶㧘᧼၂ᚑᵏ㧘᧛㊁ஜᄥ㇢㧖╙࿁ᄢ᳇ⅣႺቇળᐕળ㧔੩ㇺᄢ᳇ᳪᨴ‛⾰ߩ᷹ⷰᏒ㧕㧘ᐔᚑᐕ᦬㧙ᣣ㧙਻Ꮊ 㧖 ࿖┙ⅣႺ⎇ⓥᚲ

ർㇱ࿾ၞߦ߅ߌࠆᾍ㔵ߩ⊒↢
ߦߟ޿ߡ㧙

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ቇળฬ㧔႐ᚲ㧕㧘ᐕ᦬ᣣᄢ㒽߆ࠄߩ⒖ᵹߦ઻߁ᄢ᳇ᳪ ᧼၂ᚑᵏ㧘ਅේቁ┨㧘᧛㊁ஜᄥ㇢㧖╙࿁ᄢ᳇ⅣႺቇળᐕળ㧔੩ㇺᨴ‛⾰ߩ᷹ⷰ㧙㤛⍾⍾ߓࠎߦ 㧖 ࿖┙ⅣႺ⎇ⓥᚲ

Ꮢ㧕㧘ᐔᚑᐕ᦬㧙ᣣࠃࠆࠨࡦࡊ࡝ࡦࠣᤨߩࠕ࡯࠹
ࠖࡈࠔࠢ࠻ߩᓇ㗀ߦߟ޿ߡ㧙㜞ᵴᕈ὇⚛❫⛽ࠍ↪޿ߚᴪ㆏ ਅේቁ┨ⅣႺᡷༀ⺞ᩏ⎇ⓥᚑᨐ⊒⴫ળ㧔᧲ឃࠟࠬ೥ᷫᛛⴚߦ㑐ߔࠆ⺞ᩏ੩ㇺ㧕ᐔᚑᐕ᦬ᣣ

ඳᄙḧߦ߅ߌࠆࡎ࠻࠻ࠡࠬࠟ ᾢ⼱ඳผ㧘ጊፒᗅ⟵㧖㧘ᷰㄝ੫৻㧖㧘⮮↰ஜ৻㧖╙࿁ⅣႺᎿቇ⎇ⓥࡈࠜ࡯࡜ࡓ

ࠗ߇⽺㉄⚛᳓႙ߦਈ߃ࠆᓇ㗀๺᱌ጊᏒ㧕㧘ᐔᚑᐕ᦬ᣣ㧖 ⑔ጟᄢቇ㧘㧖 ਻ᎺⅣႺ▤ℂදળᐩ㕙ࠈᐥᴺߦࠃࠆḓᴧߩᵺൻ ጊፒᗅ⟵㧖㧘ᷰㄝ੫৻㧖㧘ᾢ⼱ඳผ㧘ർ㊁⟵ೣ㧖╙࿁ⅣႺᎿቇ⎇ⓥࡈࠜ࡯࡜ࡓ

ࠪࡒࡘ࡟࡯࡚ࠪࡦ

๺᱌ጊᏒ㧕㧘ᐔᚑᐕ᦬ᣣ㧖 ⑔ጟᄢቇ㧘㧖 㑐᧲ቇ㒮ᄢቇᐩ ᵆ ਛ ߩ ㉄ ើ ⊒ ᕈ ⎫ ൻ ‛ ᷰㄝ੫৻㧖㧘ጊፒᗅ⟵㧖㧘ᾢ⼱ඳผ㧘⮮੗ᥙᒾ㧖㧘 ╙࿁ⅣႺᎿቇ⎇ⓥࡈࠜ࡯࡜ࡓ
㧔AVS㧕ߣ㉄ൻㆶర㔚૏㧔ORP㧕 ႇᢘ㧖
ߩᄌേ․ᕈߦ㑐ߔࠆ⎇ⓥ

๺᱌ጊᏒ㧕㧘ᐔᚑᐕ᦬ᣣ㧖 ⑔ጟᄢቇ㧘㧖 ਻ᎺⅣႺ▤ℂදળ

ᦨㄭߩ㒠ਅ‛ਛߦᬌ಴ߐࠇࠆ ⍹Ꮉ㓁৻㧖㧘૒‫ᧁޘ‬ବⴕ㧖㧘ᬰፒᐘ▸㧘↰਄྾㇢㧘㋈ ╙࿁ⅣႺ᡼኿⢻ኾ㐷⎇ⓥળߣᄢ㒽⿠Ḯࠛࠕࡠ࠱࡞ߣ ᧁ೑ቁ㧖



ߩ㑐ㅪ

㧔ߟߊ߫Ꮢ 㧕㧘ᐔᚑᐕ᦬㧙㧖 ችၔ⋵ේሶജ࠮ࡦ࠲࡯㧘㧖 ጊᒻᄢቇ὾ළ㘧Ἧࠍේᢱߣߒߚࠦࡦࠢ ⍹ᯅⲢሶ㧘࿯↰ᄢテ㧘᳗ᷗ⟵ቁ㧘ဈᧄ㓶ਃ㧖ᣣᐔᚑᐕᐲᣣᧄ᳓ⅣႺቇળ਻Ꮊ

࡝࡯࠻㛽᧚ߦ฽߹ࠇࠆ㊀㊄ዻ 㧖 ૑෹㊄ዻ㋶ጊ㧔ᩣ㧕ᡰㇱ⎇ⓥ⊒⴫ળ㧔ർ਻ᎺᏒ㧕㧘㘃෸߮࠳ࠗࠝࠠࠪࡦ㘃ߩ⹏ଔᐔᚑᐕ᦬ᣣ

RDF ὾ළἯ╬ߩ᳓๺෻ᔕߦࠃ 㠽⠀ፄ᮸㧘࿯↰ᄢテ㧘㜞ᯅᶈม㧘᳗ἑ⺈㧘ቝㇺች ᑄ᫈‛ቇળ⎇ⓥ⊒⴫ળ㧔ߟߊ߫ࠆ㋦ṁ಴ᛥ೙ᯏ᭴ߦߟ޿ߡ

ᓃ㧘㥱⮮⟵᣿㧖㧘⑔ర⾆ม㧖㧘ᰞ੗㓉༑㧖㧘ਃቛᷕ৻ Ꮢ㧕㧘ᐔᚑᐕ᦬ᣣ㧙ᣣ㧘ዊ᧻ᄞሶ㧖㧘㒋ᧄዏቁ㧖㧘೨↰๺♿㧖㧖㧖 ਃ੗㋶ጊ㧘㧖 ਃ੗㋶ጊ࠮ࡔࡦ࠻㧘㧖 㔚Ḯ㐿⊒㧘㧖 Ꮏᛛ࠮ࡦ࠲࡯㧘㧖 ࡝ࠨࠗࠢ࡞ផㅴቶ
቟ቯဳ↥ᬺᑄ᫈‛ᦨ⚳ಣಽ႐ ࿯↰ᄢテ㧘㜞ᯅᶈม㧘ቝㇺችᓃ㧘ፉጟ㓉ⴕ 㧖㧘ਛ ᑄ᫈‛ቇળ⎇ⓥ⊒⴫ળ㧔ߟߊ߫ߩᾲ⿒ᄖ✢↹௝ⵝ⟎ߦࠃࠆ⋙ ጊ⵨ᢥ㧖㧘ዊችືᐔ㧖
ⷞᚻᴺߩᬌ⸛

Ꮢ㧕㧘ᐔᚑᐕ᦬ᣣ㧙ᣣ㧖 ਻Ꮊᄢቇ

⑔ጟ⋵ਅߢ⊒⷗ߐࠇߚ࠮ࡑ࡞ ✜ᣇஜ㧘ਛፉᷕ㧖ᣣᧄ㒽᳓ቇળ╙࿁ᄢળ㧔ጟጊࡅࡔ࠼ࡠࡓࠪዻ ࡅࡔ࠼ࡠࡓࠪ 㧖 ਻ᎺᄢቇᏒ㧕㧘ᐔᚑᐕ᦬ᣣ

⑼ ߣߘߩ↢ᕷ႐ᚲḨේᬀ↢ᓳరᚻᴺߣߒߡߩ߆ 㗇↰㓉৻㧘⌀㍿ᔀ㧖ᣣᧄ᥊ⷰ↢ᘒቇળ╙࿁ᄢળ

߈⿠ߎߒಣℂߩലᨐ㧙ᐔየบ 㧖 ർ਻ᎺᏒ┙⥄ὼผ࡮ᱧผඳ‛㙚㧔᧲ᐢፉᏒ㧕㧘ᐔᚑᐕ᦬ᣣ

ᐢ⼱Ḩේߩ੐଀㧙⸘㧔࿖ౝቇળ㧔ో࿖㧕ઙԚ࿖ౝቇળ㧔࿾ᣇ㧕
Ṷ

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ቇળฬ㧔႐ᚲ㧕㧘ᐕ᦬ᣣ

ਇᴺᛩ᫈⃻႐࿯ფਛߩ⎫㉄ㆶర⩶ߦ ၳᎹ๺⟤㧘ựፒశብ㧘㜞ᯅᶈม㧘╙࿁ᣣᧄ⚦⩶ቇળ਻Ꮊᡰㇱ✚ળߟ޿ߡችፒ㧕㧘ᐔᚑᐕ᦬ᣣ

਎⦟ᥰਯ㧘⼱ญೋ⟤㧖㧖↥ᬺක⑼ᄢቇ
ਇᴺᛩ᫈⃻႐ߩ࿯ფ߆ࠄᬌ಴ߐࠇߚ ựፒశብ㧘ၳᎹ๺⟤㧘਎⦟ᥰਯ㧘╙࿁ᣣᧄ⚦⩶ቇળ਻Ꮊᡰㇱ✚ળ⎫ ㉄ ㆶ ర ⩶ ߣ ࡔ ࠲ ࡦ ↢ ᚑ ⩶ ߩ   㜞ᯅᶈม㧘⼱ญೋ⟤㧖ችፒ㧕㧘ᐔᚑᐕ᦬ᣣ

SrDNA ߦࠃࠆ⩶⒳ߩหቯ

㧖↥ᬺක⑼ᄢቇ

࠙ࠚ࡞ࠪࡘ⩶ࠍේ࿃ߣߔࠆ㘩ਛᲥ੐ ựፒశብ㧘᧛਄శ৻㧘㐳㊁⧷ବ㧘⑔ጟ⋵౏ⴐⴡ↢ቇળ㧔⑔ጟᏒ㧕଀ߦߟ޿ߡᐔᚑᐕ᦬ᣣ

ၳᎹ๺⟤㧘㜞↰ᥓ㧘ᵿፒિ৻㧘᧻᳗ߒߩ߱㧘㜞↰ೣሶ㧘᪢ፒ⺈ᴦᶎ႐ᣉ⸳ߦ߅ߌࠆࠕࡔ࡯ࡃಽᏓ⺞ᩏ ᧛਄శ৻㧘㐳㊁⧷ବ㧘ự㦮శብ㧘ၳᎹ๺⟤㧘 ਻Ꮊⴡ↢ⅣႺᛛⴚද⼏ળ㧔㇊ⷓᏒ㧕ߩ৻଀⍹㤤㕏ዏ㧘ጊፒ⍮⛗㧘᪢ፒߺߤࠅ

ᐔᚑᐕ᦬ᣣ

࿯ფਛߩࡔ࠲ࡦ↢ᚑ⩶ߩၭ㙃ᴺߩᬌ ਎⦟ᥰਯ㧘ựፒశብ㧘㜞ᯅᶈม㧘╙࿁ᣣᧄ⚦⩶ቇળ⸛ߦߟ޿ߡ࠙ࠗ࡞ࠬቇળ

ၳᎹ๺⟤㧘⼱ญೋ⟤㧖㧖↥ᬺක⑼ᄢቇ

╙࿁ᣣᧄ

਻Ꮊᡰㇱ✚ળ

㧔ችፒᏒ㧕㧘ᐔᚑᐕ᦬ᣣ

/ࠪ࡯࠭ࡦߩࠗࡦࡈ࡞ࠛࡦࠩᵹ ᫃ේᷕ⌬㧘ᳯ⮮⦟᮸㧘਎⦟ᥰਯ㧘╙࿁਻Ꮊⴡ↢ⅣႺᛛⴚද⼏ળⴕᩣߩㆮવሶ⸃ᨆ

㧔㇊ⷓᏒ㧕㧘ᐔᚑᐕ᦬ᣣ

ජ‫ޘ‬๺ൎᏆ

㜞ㅦṁᇦ᛽಴ߣᄢ㊂⹜ᢱᵈ౉ࠍ↪޿ߚ㘩 ၳዞ⧷㧘㘧⍹๺ᄢ㧘⧃Ⴆ↱♿㧘╙࿁਻Ꮊⴡ↢ⅣႺᛛⴚද⼏ળຠਛ࠳ࠗࠝࠠࠪࡦ㘃ߩಽᨆᣇᴺߦߟ޿ߡ ਛᎹ␞ሶ㧘㘵↰㓉㓶㧔㇊ⷓᏒ㧕㧘ᐔᚑᐕ᦬ᣣ㧙ᣣ㘩ຠਛ⥇⚛ൻ࠳ࠗࠝࠠࠪࡦ෸߮ߘߩ ਛᎹ␞ሶ㧘⧃Ⴆ↱♿㧘㘧⍹๺ᄢ㧘╙࿁਻Ꮊⴡ↢ⅣႺᛛⴚද⼏ળ㑐ㅪൻว‛ߩಽᨆ

㧔㇊ⷓᏒ㧕㧘ᐔᚑᐕ᦬ᣣ㧙ᣣၳዞ⧷㧘㘵↰㓉㓶⑔ጟ⋵ߦ߅ߌࠆஜᐽ㘩ຠ࡮ήᛚ⹺ή ᫪↰㇌ᱜ㧘Ძ೑㓉⟤㧘⧃Ⴆ↱♿㧘╙࿁⑔ጟ⋵౏ⴐⴡ↢ቇળ⸵นක⮎ຠߩಽᨆ੐଀

㧔⑔ጟᏒ㧕㧘ᐔᚑᐕ᦬ᣣ

ਛᎹ␞ሶ㘩ຠਛߩ⥇⚛ൻ࠳ࠗࠝࠠࠪࡦ㘃෸߮ ⧃Ⴆ↱♿㧘ਛᎹ␞ሶ㧘ၳዞ⧷㧘╙࿁ో࿖ⴡ↢ൻቇᛛⴚද⼏ળᐕળߘߩ㑐ㅪൻว‛ߩಽᨆ㧔╙㧞ႎ㧕๺᱌ጊᏒ 㧘ᐔᚑᐕ᦬ᣣ㧙ᣣ㘧⍹๺ᄢ㧘㘵↰㓉㓶㘩ຠߦ߅ߌࠆ⥇⚛ൻࠫࡈࠚ࠾࡞ࠛ࡯ ⧃Ⴆ↱♿㧘ਛᎹ␞ሶ㧘㘧⍹๺ᄢ㧘

ⅣႺࡎ࡞ࡕࡦቇળ╙࿁⎇ⓥ⊒⴫ળ࠹࡞ߩᳪᨴታᘒ

ၳዞ⧷㧘㘵↰㓉㓶㧔઄บᏒ㧕㧘ᐔᚑᐕ᦬ᣣ㧙ᣣណ᳓ེߦ↱᧪ߔࠆ㋦ߩᳪᨴ੐଀

⍹ᯅⲢሶ㧘᧻የብ㧘╣የᢕሶ㧘╙࿁਻Ꮊⴡ↢ⅣႺᛛⴚද⼏ળਛ᧛෶ༀ㧘਄↰ୃ㧔㇊ⷓᏒ㧕㧘ᐔᚑᐕ᦬㧙ᣣ

㧖ⅣႺ଻ో⺖

㧖

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⠪

ቇળฬ㧔႐ᚲ㧕㧘ᐕ᦬ᣣඳᄙḧߦ߅޿ߡ⽺㉄⚛᳓႙ߦࠃࠅᢣ ᾢ⼱ඳผ㧘ጊፒᗅ⟵㧖㧘ᷰㄝ੫৻㧖㧘ᐔᚑᐕᐲ᳓ⅣႺቇળ਻Ꮊᡰㇱ⎇ⓥᱫߔࠆࡎ࠻࠻ࠡࠬࠟࠗߩቯ㊂ൻ⊒⴫ળ ർ਻ᎺᏒ ᐔᚑᐕ᦬ᣣ

⮮↰ஜ৻㧖㧖 ⑔ጟᄢቇ㧘㧖 ਻ᎺⅣႺ▤ℂදળᐩ↢േ‛߆ࠄ⷗ߚᵹ㊂Ⴧടߩ⹏ଔ

ጊፒᱜᢅ㧘✜ᣇஜ㧘᧖ᵏᤘᄢጊᎹ࡮ਃ㓊ᎹߩⅣႺߦߟ޿ߡ⠨߃ࠆࠪࡦࡐࠫ࠙ࡓ ᣣ↰Ꮢ 㧘ᐔᚑᐕ᦬ᣣ

⑔ጟ⋵ਅᴡᎹߦ߅ߌࠆࡅࡔ࠼ࡠࡓࠪ ✜ᣇஜ╙࿁਻Ꮊⴡ↢ⅣႺᛛⴚද⼏ળ⑼ߩಽᏓߣߘߩ․ᓽ

㧔㇊ⷓᏒ㧕㧘ᐔᚑᐕ᦬ᣣ

⑔ጟ⋵ߦ߅ߌࠆࡂࡦࡁࠠ⟲⪭ߩಽᏓ ౐↰ቬ৻㇢㧖㧘㗇↰㓉৻㧘⮀ቁᄦ㧖ᣣᧄㅧ࿦ቇળ਻Ꮊᡰㇱᐔᚑᐕᐲᄢળ

ߣ↢⢒┙࿾㧔೎ᐭᏒ㧕㧘ᐔᚑᐕ᦬ᣣ

⸘㧔࿖ౝቇળ㧔࿾ᣇ㧕㧕

㧖਻Ꮊᄢቇ


ઙ

㧔㧠㧕ႎ๔ᦠ৻ⷩ
ᆔ⸤੐ᬺฬ

ႎ

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ᐔᚑᐕᐲෘ↢ഭ௛⑼ቇ⎇ⓥ 㧔ಽᜂ⎇ⓥႎ๔ᦠ㧕
⾌⵬ഥ㊄

╩

⠪

⊒ⴕᐕ᦬

❱↰⡸㧖 ಽᜂ⎇ⓥ⠪㧕㧘ട⮮రඳ㧘ᐔᚑᐕ᦬

߇ࠎ੍㒐╬ஜᐽ⑼ ஜᐽෂᯏ▤ℂ੐଀ߩ࠺࡯࠲ࡌ࡯ࠬൻ ᫃ේᷕ⌬ઁቇ✚ว⎇ⓥ੐ᬺ

ߣߘߩ೑↪ߦ㑐ߔࠆ⎇ⓥᐔᚑᐕᐲෘ↢ഭ௛⑼ቇ⎇ⓥ 㧔ಽᜂ⎇ⓥႎ๔ᦠ㧕⵬ഥ㊄ၫ㧖ᄢ㒋ᐭ౏ⴐⴡ↢⎇ⓥᚲ
㊄↰㤗ℂሶ㧖 ಽᜂ⎇ⓥ⠪ 㧘ട⮮ ᐔᚑᐕ᦬

ஜᐽ⑼ቇ✚ว⎇ⓥ੐ ஜᐽෂᯏ▤ℂᖱႎࡀ࠶࠻ࡢ࡯ࠢ᭴▽ రඳ㧘◉ේᔒ㇢㧘↲ේ㓉⍫ઁᬺߦ㑐ߔࠆ⎇ⓥ㧖᧲੩ㇺஜᐽ቟ో⎇ⓥ࠮ࡦ࠲࡯ᐔᚑᐕᐲෘ↢ഭ௛⑼ቇ⎇ⓥ 㧔ಽᜂ⎇ⓥႎ๔ᦠ㧕⾌⵬ഥ㊄ጟᕶ৻㇢㧘↲ේ㓉⍫ᐔᚑᐕ᦬

㘩ຠ቟ో⏕଻⎇ⓥ ᾲᇦ૕ߩੱ૕ᓇ㗀ߣߘߩᴦ≮ᴺ╬ߦ

੐ᬺ

㑐ߔࠆ⎇ⓥ

㧙ᴤ∝৻ᢧᬌ⸻ߩో࿖

㓸⸘⚿ᨐ෸߮ᴤ∝ᖚ⠪࠺࡯࠲ࡌ࡯ࠬ
ߩ᭴▽㧙ᐔᚑᐕᐲᏒ↸᧛࿾ၞ଻ஜᵴ ᐔᚑᐕᐲᏒ↸᧛࿾ၞ଻ஜᵴേᡰេ Ꮢ↸᧛࿾ၞ଻ஜᵴേᡰេ੐ᬺᬌ ᐔᚑᐕ᦬
േᡰេ੐ᬺ੐ᬺ㧔࿾ၞ⸻ᢿ㧕ႎ๔ᦠ⸛ᆔຬળ㧔ጟᕶ৻㇢㧘↲ේ㓉⍫㧕ⅣႺ⋭ᆔ⸤ᬺോ

ᐔᚑᐕᐲൻቇ‛⾰ⅣႺᳪᨴታᘒ⺞ ർ⋥ሶ㧘㘧⍹๺ᄢ㧘㤥Ꮉ㓁৻㧘 ᐔᚑᐕ᦬
ᩏ㧔ೋᦼⅣႺ⺞ᩏ㧕ႎ๔ᦠ

ᄢ㊁ஜᴦ㧘᧻ᨑ㓉ᒾ㧘᪉ᧁᑪᴦ㧘ᩉᎹᱜ↵㧘ጤᧄ⋿ੑ㧘ዊᨋᔀ㧖㧘₹੗ᵗሶ㧖㧖⑔ጟ⋵ⅣႺㇱⅣႺ଻ో⺖ᐔᚑᐕᐲൻቇ‛⾰ⅣႺᳪᨴታᘒ⺞ ർ⋥ሶ㧘㘧⍹๺ᄢ㧘㤥Ꮉ㓁৻㧘 ᐔᚑᐕ᦬
ᩏ㧔᥸㔺㊂⺞ᩏ㧕ႎ๔ᦠ

ᄢ㊁ஜᴦ㧘᧻ᨑ㓉ᒾ㧘᪉ᧁᑪᴦ㧘ᩉᎹᱜ↵㧘ጤᧄ⋿ੑ㧘ዊᨋᔀ㧖㧘₹੗ᵗሶ㧖㧖⑔ጟ⋵ⅣႺㇱⅣႺ଻ో⺖ᐔᚑᐕᐲൻቇ‛⾰ⅣႺᳪᨴታᘒ⺞ ർ⋥ሶ㧘㘧⍹๺ᄢ㧘㤥Ꮉ㓁৻㧘 ᐔᚑᐕ᦬
ᩏ㧔ࡕ࠾࠲࡝ࡦࠣ⺞ᩏ㧕ႎ๔ᦠ

ᄢ㊁ஜᴦ㧘᧻ᨑ㓉ᒾ㧘᪉ᧁᑪᴦ㧘ᩉᎹᱜ↵㧘ጤᧄ⋿ੑ㧘ዊᨋᔀ㧖㧘₹੗ᵗሶ㧖㧖⑔ጟ⋵ⅣႺㇱⅣႺ଻ో⺖ᐔᚑᐕᐲෘ↢ഭ௛⑼ቇ⎇ⓥ 㧔✚᜝࡮ಽᜂ⎇ⓥႎ๔ᦠ㧕⾌⵬ഥ㊄੐ᬺ㆙⮮ථ㇢㧖㧔ਥછ⎇ⓥ⠪㧕ஜᐽ⑼ቇ✚ว⎇ⓥ ᷷ᴰ࡮౏ⴐᶎ႐㧘ߘߩઁߩ᷷᳓ⅣႺ ᧛਄శ৻ߦ߅ߌࠆࠕࡔ࡯ࡃᕈ㜑⤑⣖Ἳߩ∛ේ 㧖࿖┙ᗵᨴ∝⎇ⓥᚲ
૕ Naegleria fowleri ߩ∉ቇߣ∛ේᕈߦ㑐ߔࠆ⎇ⓥᐔᚑᐕ᦬

ᆔ⸤੐ᬺฬႎ๔ᦠฬᐔᚑᐕᐲෘ↢ഭ௛⑼ቇ⎇ⓥ 㧔✚᜝࡮ಽᜂ⎇ⓥႎ๔ᦠ㧕
⾌⵬ഥ㊄

ၫ

╩

⠪

ዊᾢᗆੑ㧖㧔ਥછ⎇ⓥ⠪㧕㧘⊒ⴕᐕ᦬ᐔᚑᐕ᦬

㘩ຠ࡮ൻቇ‛⾰቟ ኈེ൮ⵝ⹣ૐ㉄ᕈ㘩ຠߩࡏ࠷࡝࠿ࠬ ၳᎹ๺⟤㧘᧛਄శ৻㧘㐳㊁⧷ବ㧘ో✚ว⎇ⓥ੐ᬺ

㘩ਛᲥߦኻߔࠆ࡝ࠬࠢ⹏ଔ

ựፒశብ㧘㜞↰ᥓઁ㧖ጟጊᄢቇᐔᚑᐕᐲෘ↢⑼ቇ⎇ⓥ⾌⵬ 㧔✚᜝࡮ಽᜂ⎇ⓥႎ๔ᦠ㧕ഥ㊄ዊᾢᗆੑ㧖㧔ਥછ⎇ⓥ⠪㧕㧘ᐔᚑᐕ᦬

㘩ຠ࡮ൻቇ‛⾰቟ో✚ ኈེ൮ⵝ⹣ૐ㉄ᕈ㘩ຠߩࡏ࠷࡝࠿ࠬ ၳᎹ๺⟤㧘ựፒశብ㧘᧛਄శ৻㧘ว⎇ⓥ੐ᬺ㘩ਛᲥߦኻߔࠆ࡝ࠬࠢ⹏ଔ

㐳㊁⧷ବ㧘⍹㤥㕏ዏઁ㧖ጟጊᄢቇᐔᚑᐕᐲᑄ᫈‛ಣℂ╬⑼ቇ 㧔✚᜝࡮ಽᜂ⎇ⓥႎ๔ᦠ㧕⎇ⓥ੐ᬺ

⼱ญೋ⟤㧖 ઍ⴫⎇ⓥ⠪ᐔᚑᐕ᦬

ᑄ᫈‛ಣಽ႐ߩࡃࠗࠝ⹏ଔߦ㑐ߔࠆ ၳᎹ๺⟤㧘ựፒశብ㧘਎⦟ᥰਯ㧘⎇ⓥ㧔⎫㉄ㆶర⩶ߩၭ㙃㧕㜞ᯅᶈมઁ㧖↥ᬺක⑼ᄢቇ

㧔✚᜝࡮ಽᜂ⎇ⓥႎ๔ᦠ㧕⼱ญೋ⟤㧖㧔ઍ⴫⎇ⓥ⠪㧕ᐔᚑᐕ᦬

ᑄ᫈‛ಣಽ႐ߩࡃࠗࠝ⹏ଔߦ㑐ߔࠆ ựፒశብ㧘ၳᎹ๺⟤㧘⍹㤥㕏ዏ
⎇ⓥ㧔ህ᳇ᕈ⚦⩶ߩ SrDNA Ⴎၮ 㧖↥ᬺක⑼ᄢቇ
㈩೉᳿ቯߦࠃࠆᓸ↢‛⟲㓸⸃ᨆ㧕㧔✚᜝࡮ಽᜂ⎇ⓥႎ๔ᦠ㧕⼱ญೋ⟤㧖 ઍ⴫⎇ⓥ⠪ ᐔᚑᐕ᦬

ᑄ᫈‛ಣಽ႐ߩࡃࠗࠝ⹏ଔߦ㑐ߔࠆ ਎⦟ᥰਯ㜞ᯅᶈม㧘ựፒశብ㧘⎇ⓥ㧔ࡔ࠲ࡦ↥↢⩶ߩၭ㙃㧕ၳᎹ๺⟤㧘㜞↰ᥓ㧘ቝㇺችᓃ㧖↥ᬺක⑼ᄢቇ

ᐔᚑᐕᐲෘ↢ഭ௛⑼ቇ⎇ⓥ 㧔✚᜝࡮ಽᜂ⎇ⓥႎ๔ᦠ㧕
⾌⵬ഥ㊄
⎇ⓥ੐ᬺ

ᷰㄝᴦ㓶㧖㧔ਥછ⎇ⓥ⠪㧕㧘ᐔᚑᐕ᦬

ᣂ⥝࡮ౣ⥝ᗵᨴ∝ ࡄ࡞ࠬࡈࠖ࡯࡞࠼ࠥ࡞㔚᳇ᵒേᴺ ၳᎹ๺⟤㧘᧛਄శ৻ઁ
㧔 PFGE㧕ߩᮡḰൻ෸߮↹௝⸻ᢿࠍ 㧖࿖┙ᗵᨴ∝⎇ⓥᚲၮ⋚ߣߒߚಽᢔဳࠪࠬ࠹ࡓߩ᦭ലᕈ
ߦ㑐ߔࠆ⎇ⓥ㧔✚᜝࡮ಽഀ⎇ⓥႎ๔ᦠ㧕૒‫ᧁޘ‬ᰴ㓶㧖㧔ਥછ⎇ⓥ⠪㧕㧘ᐔᚑᐕ᦬

⊖ᣣຕ⩶㧘ࠫࡈ࠹࡝ࠕ⩶㧘ࡑࠗࠦࡊ ၳᎹ๺⟤㧘᧛਄శ৻ઁ
࡜࠭ࡑ╬ߩ⥃ᐥಽ㔌⩶ߩ෼㓸ߣಽሶ 㧖࿖┙ᗵᨴ∝⎇ⓥᚲ∉ቇ⊛⸃ᨆߦ㑐ߔࠆ⎇ⓥᐔᚑᐕᐲෘ↢ഭ௛⑼ቇ⎇ⓥ 㧔ಽᜂ⎇ⓥႎ๔ᦠ㧕⾌⵬ഥ㊄ᬺජ‫ޘ‬๺ൎᏆᳯ⮮⦟᮸㍿ፉ⨃᮸㧖 ᐔᚑᐕ᦬

ࠛࠗ࠭ኻ╷⎇ⓥ੐ HIV ߩᬌᩏ૕೙ߩ᭴▽ߦ㑐ߔࠆ⎇ ฎᐣᙗᶈ㧖ᨋ⚐㧖ⓥ㧖਻Ꮊᄢቇකቇㇱᆔ⸤੐ᬺฬ
ෘ↢ഭ௛⋭ᆔབྷ੐ᬺ

ႎ

๔

ᦠ

ฬ

ၫ

╩

⠪

⊒ⴕᐕ᦬

ක≮↪ක⮎ຠߩຠ⾰ౣ⹏ଔߦଥࠆ౏ Ძ೑㓉⟤㧘᫪↰㇌ᱜ㧘ਛᎹ␞ሶ㧘 ᐔᚑᐕ᦬
⊛ṁ಴⹜㛎㧔᩺㧕ߩᅷᒰᕈᬌ⸽╬ႎ 㘵↰㓉㓶๔ᦠ㧔ᐔᚑᐕᐲ㧕ᐔᚑᐕᐲෘ↢ഭ௛⑼ቇ⎇ⓥ 㧔ಽᜂ⎇ⓥႎ๔ᦠ㧕⾌⵬ഥ㊄૒‫ᧁޘ‬ਭ⟤ሶ㧖☨⼱᳃㓶㧖㘵↰ ᐔᚑᐕ᦬

㘩ຠ࡮ൻቇ‛⾰቟ ࠳ࠗࠝࠠࠪࡦߩᳪᨴታᘒᛠី෸߮៨ 㓉㓶㧘⼾↰ᱜᱞ㧖㧘ᄤୖศ┨㧖ో✚ว⎇ⓥ੐ᬺ

ขૐᷫൻߦ㑐ߔࠆ⎇ⓥ㧖 ࿖┙ක⮎ຠ㘩ຠⴡ↢⎇ⓥᚲ㧖 ታ〣ᅚሶᄢቇ

㧔✚᜝࡮ಽᜂ⎇ⓥႎ๔ᦠ㧕ਛᎹ␞ሶ㧘ၳዞ⧷

ᐔᚑᐕ᦬

㘩ຠਛ⥇⚛ൻ࠳ࠗࠝࠠࠪࡦ෸߮ߘߩ
㑐ㅪൻว‛⾰ߩᳪᨴታᘒߩ⸃᣿ߦ㑐ߔࠆ⎇ⓥ౏ኂஜᐽⵍኂ⵬ఘ੍㒐දળᆔ 㜞ᵴᕈ὇⚛❫⛽ࠍ↪޿ߚᴪ㆏ឃࠟࠬ ਅේቁ┨㧘ᣂ⼱ବੑ㧘ജኼ㓶㧘 ᐔᚑᐕ᦬
⸤ᬺോ೥ᷫᛛⴚߦ㑐ߔࠆ⺞ᩏႎ๔ᦠ᧼၂ᚑᵏᐔᚑᐕᐲ⁛┙ⴕ᡽ᴺੱ᳓↥ ᳓ਛ᦭ᯏ෸߮ήᯏൻቇ‛⾰ߩๆ⌕⢻ ᰞ੗೑ᒾ㧘ਅේቁ┨㧘ജኼ㓶㧘 ᐔᚑᐕ᦬
✚ว⎇ⓥ࠮ࡦ࠲㧙ᆔ⸤ᬺോߦ㑐ߔࠆᬌ⸛

ᐔᚑᐕᐲෘ↢ഭ௛⑼ቇ⎇ⓥ 㧔ಽᜂ⎇ⓥႎ๔ᦠ㧕᧼၂ᚑᵏജኼ㓶㧘ᩉᎹᱜ↵㧘ᄢ⍹⥝ᒄ㧘 ᐔᚑᐕ᦬

⾌⵬ഥ㊄↢ᵴ⑼ቇ቟ో✚ว ో࿖ߦ߅ߌࠆቶౝⓨ᳇ਛൻቇ‛⾰ߩ ጤᧄ⌀ੑ⎇ⓥ੐ᬺታᘒߦ㑐ߔࠆ⎇ⓥ㧔⑔ጟ⋵㧕ⴕ᡽ଐ㗬᳓⾰ⅣႺၮḰ㘃ဳ⷗⋥ߒ⺞ᩏᬺോႎ ᾢ⼱ඳผ㧘ᔒ᳓ାᒄ㧘↰ਛ⟵ੱ㧘 ᐔᚑᐕ᦬
๔ᦠ㧙⼾೨ᶏᵹ౉ᴡᎹ㧔ධㇱ㧕✬㧙 ᧻የብ㧘ਛ᧛෶ༀ㧙╳ᓟᎹ਄ᵹᴡᎹⅣႺ․ᕈᬌ⸛ળ㧔ᐩ ጊፒᱜᢅ㧘✜ᣇஜ㧘᧖ᵏᤘᐔᚑᐕ᦬

↢േ‛⺞ᩏ㧕ᐕᐲᐩ↢േ‛⺞ᩏ⚿ᨐႎ๔ᦠⅣႺ⋭ᆔ⸤ᬺോ

ᐔᚑᐕᐲⅣႺ⋭ᆔ⸤ᬺോ⚿ᨐႎ๔ 㗇↰㓉৻㧘ጊፒᱜᢅᦠᐔᚑᐕ᦬

㉄ᕈ㔎ࡕ࠾࠲࡝ࡦࠣ㧔࿯ფ࡮ᬀ↢㧕⺞ᩏᒾጊᎹᵹၞ↢ᵴឃ᳓ኻ╷ផㅴ ᒾጊᎹᵹၞ↢ᵴឃ᳓ኻ╷ផㅴ⸘↹᪢ፒᐘ▸㧘⍹ᯅⲢሶ㧘✜ᣇஜ㧘 ᐔᚑᐕ᦬

⸘↹╷ቯᬺോ

㗇↰㓉৻ᆔ⸤੐ᬺฬ

ႎ

๔

ᦠ

ฬ

ၫ

╩

⠪

⊒ⴕᐕ᦬

ᐔᚑᐕᐲ࡝ࠨࠗࠢ࡞✚ว⎇ ‫ޟ‬ㇺᏒࠧࡒ὾ළἯࠍ೑↪ߒߚࠛࠦ࡟ ቝㇺችᓃ㧘᳗ἑ⺈㧘㠽⠀ፄ᮸㧘 ᐔᚑᐕ᦬
ⓥ࠮ࡦ࠲࡯౒ห⎇ⓥࡊࡠࠫࠚ ࡦࠟ⵾ㅧᛛⴚߩ㐿⊒ࡊࡠࠫࠚࠢ࠻⎇ 㜞ᯅᶈม㧘࿯↰ᄢテࠢ࠻ⓥߦଥࠆ቟ోᕈ⹜㛎ᬺോ‫ޠ‬ႎ๔ᦠ‫↥ޟ‬ᬺᑄ᫈‛♽ᑄࡊ࡜ࠬ࠴࠶ࠢߩ㜞 ቝㇺችᓃ㧘᳗ἑ⺈㧘㠽⠀ፄ᮸㧘 ᐔᚑᐕ᦬
ല₸ᴤൻⵝ⟎ߩ㐿⊒ࡊࡠࠫࠚࠢ࠻⎇ 㜞ᯅᶈม㧘࿯↰ᄢテⓥ㧔↢ᚑᴤߩಽᨆ㧕‫ޠ‬ႎ๔ᦠᐔᚑᐕᐲ࡝ࠨࠗࠢ࡞✚ว⎇ ὾ළἯߩ᦭ല೑↪ߦ㑐ߔࠆ⎇ⓥળቝㇺችᓃ㧘᳗ἑ⺈㧘㠽⠀ፄ᮸㧘 ᐔᚑᐕ᦬

ⓥ࠮ࡦ࠲࡯⎇ⓥળ㜞ᯅᶈม㧘࿯↰ᄢテႎ๔ᦠࡐ࡝Ⴎൻࡆ࠾࡞♽ᑄࡊ࡜ࠬ࠴࠶ࠢߦ ਅේቁ┨㧘ᰞ੗೑ᒾ㧘᧼၂ᚑᵏ
ࠃࠆⅣႺᵺൻᛛⴚߦ㑐ߔࠆ⎇ⓥᐔᚑᐕ᦬

ႎ๔ᦠ᮸⊹ߩ᦭ല೑↪⎇ⓥળ

ႎ๔ᦠ

ự㦮శብ

ᐔᚑᐕ᦬

㧙⍾႐ߦ߅ߌࠆ᮸⊹ߩ⚦⩶ߦኻߔࠆ
ലᨐ㧙ᑪ⸳ᑄ᧚ߩ࡝ࠨࠗࠢ࡞⎇ⓥળႎ๔ ᰞ੗೑ᒾ㧘↰਄྾㇢ᐔᚑᐕ᦬

ᦠᳪᵆ╬ߩ࡝ࠨࠗࠢ࡞⎇ⓥળႎ๔ᦠ ቝㇺችᓃ㧘᳗ἑ⺈㧘㠽⠀ፄ᮸㧘 ᐔᚑᐕ᦬
㜞ᯅᶈม㧘࿯↰ᄢテ⸘㧔ႎ๔ᦠ৻ⷩ㧕ઙ