10. Department of Biochemistry and Cellbiology

Sakai S, Hullin-Matsuda F, Shimada Y, Inaba T,
Miyatake H, Tanaka H, Kurahashi A, Pack CG, Kasai
RS, Kubo S, Schieber NL, Dohmae N, Tochio N,

1)

2)

Hanada K: Ceramide transport from the endoplasmic

Hagiwara K, Sasaki Y, Aida Y, Fujimori F, Kigawa T,

reticulum to the trans Golgi region at organelle

Nishibori K, Parton RG, Kusumi A, Sako Y, Anderluh G,

membrane contact sites. in "Organelle Contact Sites:

Yamashita M, Kobayashi T, Greimel P, Kobayashi T: A

From Molecular Mechanism to Diseases" (Eds., Mitsuo

novel sphingomyelin /cholesterol domain-specific probe

Tagaya & Thomas Simmen), Series: Advances inreveals the dynamics of the membrane domains during

Experimental Medicine and Biology, Springer, 997,

virus release and in Niemann-Pick type C. FASEB J.,

69-81, 201731(4), 1301-1322, 2017

Hanada K, Sugiki T: In vitro assay to extract specificYuyama K, Fujiwara T, Numata Y, Igarashi Y: Direct

lipid-transfer proteins: a lesson from the ceramide

Involvement of Arachidonic Acid in the Developmenttransport protein CERT, in “Lipidomics” (Ed., Paulof Ear Edema via TRPV3. J. Oleo. Sci., 66(6), 591-599,Wood), Series: Neuromethods, Springer, 125, 81-98,

201710) Otsuki N, Sakata M, Saito K, Okamoto K, Mori Y,

2017

4)

5)

6)

7)

8)

Sanaki T, Kasai-Yamamoto E, Yoshioka T, Sakai S,

membranes using

lipid types from phospholipid

3)

9)

Hashimoto Y, Fukasawa M, Kuniyasu H, Yagi K, Kondoh

Hanada K, Takeda M: Both sphingomyelin andM:usingcholesterol in the host cell membrane are essential

anti-claudin monoclonal antibodies to treat hepatitis andfor Rubella virus entry. J. Virol., 92, e01130-17, 2018cancer. Ann. N. Y. Acad. Sci., 1397, 5-16, 2017

(K.H. and M.T. are co-correspondence. This article was

Hagiwara K, Iwamaru Y, Tabeta N, Yokoyama T,

selected as Spotlight of the issue)

Claudin-targeteddrugdevelopment

Tobiume M: Evaluation of rapid post-mortem test kits for11) Shimasaki K, Watanabe-Takahash M, Umeda M,

bovine spongiform encephalopathy (BSE) screening inFunamoto S, Saito Y, Noguchi N, Kumagai K, Hanada

Japan: Their analytical sensitivity to atypical BSE prions.

K, Tsukahara F, Maru Y, Shibata N, Naito M, Nishikawa

Prion, 11, 113-127, 2017

K: Pleckstrin homology domain of p210 BCR-ABL

Nagata M, Izumi Y, Ishikawa E, Kiyotake R, Doi R,

interacts with cardiolipin to regulate its mitochondrial

Iwai S, Omahdi Z, Yamaji T, Miyamoto T, Bamba T,translocation and subsequent mitophagy. Genes Cells,Yamasaki

23, 22-34, 2018

S:Intracellularme tabolite

β-glucosylceramide is an endogenous Mincle ligand12) Sakuma C, Sekizuka T, Kuroda M, Kasai F, Saito K,

possessing immunostimulatory activity. Proc. Natl.

Ikeda M, Yamaji T, Osada N, Hanada K: NovelAcad. Sci. U.S.A., 114, E3285-E3294, 2017endogenous simian retroviral integrations in Vero cells:
G,implications for quality control of a human vaccine cell

Osteikoetxea-Molnár A, Bozó T, Szabó-Meleg E,substrate. Sci. Rep., 8, 644, 2018 (C.S. and T.S. areNyitrai M, Derényi I, Yamaji T, Hanada K, László Vígh,co-first authors. N.O. and K.H. are co-correspondence)

Matkó J: Nanotubes connecting B lymphocytes: High13) Ogawa M, Matsuda R, Takada N, Tomokiyo M,

impact of differentiation-dependent lipid composition

Yamamoto S, Shizukusihi S, Yamaji T, Yoshikawa Y,

on their growth and mechanics. Biochim Biophys Acta,Yoshida M, Tanida I, Koike M, Murai M, Morita H,1862, 991-1000, 2017

Takeyama H, Ryo A, Guan JL, Yamamoto M, Inoue JI,Takigawa M, Iida M, Nagase S, Suzuki H, Watari A,Yanagawa T, Fukuda M, Kawabe H, Ohnishi M ：Tada M, Okada Y, Doi T, Fukasawa M, Yagi K,

Molecular

Kunisawa J, Kondoh M: Creation of a Claudin-2 Binder

pneumoniae-targeted

and Its Tight Junction-Modulating Activity in a Human

Golgi-resident

Intestinal Model. J. Pharmacol. Exp. Ther., 363,

K63-linked ubiquitination. Cell. Microbiol., e12846,444-451, 2017

2018

TóthE

A,OszvaldÁ,Péter

M,Balogh

Makino A, Abe M, Ishitsuka R, Murate M, Kishimoto T,

mechanisms
autophagy

Rab41,

andofStreptococcusviapneumolysin,

Nedd4-1

mediated14) Shimizu Y, Shirasago Y, Kondoh M, Suzuki T, Wakita T,

HanadaK,

Yagi

antibodies against

K,Fukasawa

occludin

M: Monoclonal

completely prevented

hepatitis C virus infection in a mouse model, J. Virol.,in press15) Ogawa M, Shirasago Y, Ando S, Shimojima M, Saijo M,
Fukasawa M: Caffeic acid, a coffee-related organic acid,inhibits

infection

byseverefeverwiththrombocytopenia syndrome virus in vitro. J. Infect.
Chemother., in press