ISSN 1881ー4980

信 州 大 学 医 学 部 医 学 科・大 学 院 医 学 系 研 究 科・医 学 部 附 属 病 院 業 績 録

SCIENTIFIC ACHIEVEMENTS OF SHINSHU UNIVERSITY SCHOOL OF
MEDICINE, SHINSHU UNIVERSITY GRADUATE SCHOOL OF MEDICINE,
AND SHINSHU UNIVERSITY HOSPITAL
信州大学医学部医学科・大学院医学系研究科・医学部附属病院業績録

No.48 (2019)

第四八号（二〇一九）
二〇二〇

2020

信大
州学
大医
学学
医部
学業
部績
業録
績編
録集
編要
集項
要（
項抜粋）
信州
（平成28年12月29日改正）

１．収録対象 ２．収録対象
 信州大学医学部医学科・大学院医学系研究科・医学部附属病院及び出版委員会で信州大学医学部医学科・大学院医学系研究科・医学部附属病院及び出版委員会で認めた施設等に所属する者（当該年に在籍した者全員）認めた施設等に所属する者（当該年度に在籍した者全員）
２．収録内容 ３．収録内容
収録対象は、本文が欧文で執筆された研究業績とし、次の３項目に分ける。
研究業績を次の２項目に分ける。
１）論文
１）論文
原著、綜説、展望、症例報告、速報、予報で、査読のある学術雑誌に発表のもの。
原著、綜説、展望、症例報告、速報、予報で学術雑誌に発表のもの。
学
 術集会記録（全国的又は世界的規模の集会記録で、原著論文と同様の内容をも
学術集会記録（全国的又は世界的規模の集会記録で、原著論文と同様の内容をもち、ち、別刷が発行されているもの）
別刷が発行されているもの）
２）著書
２）著書
単行書、分担執筆。
単行書、分担執筆。
３）その他
治
 療指針、トピックス、事典等、専門的知見にもとづき執筆された、論文形式の
ただし、以下のものは除外する。
記事（イ）学会発表の抄録（邦文、欧文を問わない。論文型式をとっていても学会発表に関するもの及び１頁ものの速報は抄録とみなす）
ただし、以下のものは除外する。
（ロ）セミナー、シンポジウム、その他の講演のテキストないし記録。
（イ）学会発表の抄録（邦文、欧文を問わない。論文型式をとっていても学会発表（ハ）業務報告書（文部科学省、厚生労働省、その他助成機関への研究報告書）
に関するもの及び１頁ものの速報は抄録とみなす）（ニ）座談会記事。
（ロ）セミナー、シンポジウム、その他の講演のテキストないし記録。
（ホ）学会記。
（ハ）業and
務報告書（文部科学省、厚生労働省、その他助成機関への研究報告書）（ヘ）質疑応答（ＱＡ）
、治療指針、問題集の解説、トピックス、話題、グラビア、
（ニ）
座
談会記事。
事典等に類するもの。
（ホ）学会記。
（ト）新聞記事、教育に関する記事、人物紹介、書評、随筆など学術性が認められ（ヘ）
ないもの。 論文形式をとらない質疑応答（Q and A）、問題集の解説、話題、グラビア等に類するもの。
（チ）著者表示が団体名で個人の著者性が認められないもの。
（ト）新聞・週刊誌記事、教育に関する記事、人物紹介、書評、随筆など学術性が（リ）学術雑誌とは認められないものに発表したもの。
認められないもの。
（ヌ）訳本及び訳論文。
（チ）著者表示が団体名で個人の著者性が認められないもの。
４．収録期間
毎年１月～12月

あ

と

が

き

信州大学医学部医学科・大学院医学系研究科・医学部附属病院業績録第48号をお届けします。
信州大学医学部医学科・大学院医学系研究科・医学部附属病院業績録第 38 号をお届けします。
本業績録は過去１年間、各教室や部門などでなされた４つの活動（研究活動、教育活動、診療活動、社会貢献）のうち、研究活動の成果として公表された論文を中心にまとめたものです。
本業績録は過去１年間、各講座や部門等でなされた４つの活動（研究、教育、診療、社会貢献）
自己点検、自己評価、学内・学外への報告において、本業績録の役割は重要と思われます。この１年の研究活動を振り返り、今後の方向性を考える契機にしていただければ幸いです。
のうち、研究活動の成果として公表された論文を中心にまとめたものです。自己点検、自己評
価、学内外への報告において、本業績録の果たす役割は重要と思われます。このような観点から、2019年度の信州大学医学部の英文論文は445本でした。１本１本の論文に、様々な研究者のこの１年間の研究活動を振り返り、今後の方向性等を考える契機にしていただけたら幸いに存努力、患者さんを含めた関係者の協力が込められていると思うと感慨深い数字です。ここ数年の動きとして、医学的・科学的妥当性・信頼性が保証されていないオープンアクセス誌（いわじます。
ゆるハゲタカジャーナル）が登場し、全国の大学でも問題となっております。今回出版委員会・
医学部図書館スタッフで慎重に提出論文を精査いたしまして、本業績集をまとめさせていただ
今年度の英文論文総数は昨年度より微減し、90 年度以降で最も少ない 386 という結果となりきました。
ました。しかしながら、単なる総数のみの評価が必ずしも適切であるとは言えず、今年度の業新型コロナウイルス感染（COVID-19）拡大により、2020年における大学の診療・研究・教績の中には極めて質の高い研究成果も少なくありません。今日、卒業生の大学離れや医学科入育のあり方は一変しました。希少疾患や先端的治療などの専門的診療の制限を余儀なくされて学定員数増加等により、診療や教育活動等の業務負荷は増加の一途にあります。このような現いる施設も少なくないと思われます。学術集会や班会議を通じた直接の対面交流もほとんどできなくなりました。この状況はしばらく続くと予想されます。こうした環境で、次年度以降の状ではありますが、研究活動は大学が大学であるための大きな責務であり、外部評価基準の重信州大学医学部の業績はどのようになっていくでしょうか。希望的には、オンラインでの診療要項目であることは言うまでもありません。今後、各講座・部門等でのさらなる研究の発展をおよび学術交流が国内国外を問わず一気に加速したこと、また、地方大学ならではの苦労の種
祈念致します。
であった多くの出張がなくなり自身の研究に向き合える時間が増えたことは、もしかしたら、高品質の研究をじっくり進められるという「追い風」にもなり得るのではないかと考えています。１本の論文が研究者の人生を変えることもあります。今後どのような環境にあったとして最後に、本業績録の編集にあたりご尽力頂きました先生方、図書館職員の方々に厚く御礼申も、信州大学医学部から個性豊かな研究成果が論文として発信されること、そして、「見守り役」
し上げます。
としてこの業績集がさらに発展することを祈念いたします。
最後に、本業績録の編集にあたりご尽力頂きました先生方、図書館職員の方々に厚く御礼申
浅村英樹
し上げます。
 出 版 委 員 長：浅村英樹
古庄知己
出 版 委 員：奥山隆平、石田文宏、川股知之
出 版 委 員 長：古庄知己
医学部図書館主査：石坂憲司
出 版 委 員：清水公裕、小山淳一、前野一真
医 学 部 図 書 館：後閑壮登

信州大学医学部医学科・大学院医学系研究科
・医学部附属病院業績録 第
第 48
38 号
号
平成
年１月
日印刷
令和 23
3年
6 月 728日印刷
平成年１月
28 日発行令和 23
3年
6 月10日発行
編集兼 信 州 大 学 医 学 部
発行者 松本市旭 3 丁目 1 の 1
印刷所

藤原印刷株式会社

松本市新橋 7 の 21 番地

a

SCIENTIFIC ACHIEVEMENTS OFSHINSHU UNIVERSITY SCHOOL OF MEDICINE,SHINSHU UNIVERSITY GRADUATE SCHOOL OF MEDICINE,
AND SHINSHU UNIVERSITY HOSPITAL

信州大学医学部医学科・大学院医学系研究科・
医学部 附 属 病 院 業 績 録
No. 48( 2 0 1 9 )

2020

b

1

I. Scientific Achievements of Shinshu University School of Medicine,
Shinshu University Graduate School of Medicine,and Shinshu University HospitalContents
Aging Biology...............................................................3Transplantation and Pediatric Surgery............................17

Molecular Pathology.....................................................3

Division of Cardiovascular Surgery............................17

Metabolic Regulation....................................................3

Division of General Thoracic Surgery........................17

Cardiovascular Research...............................................4

Division of Breast and Endocrine Surgery.................18

Sports Medical Sciences...............................................4

Orthopaedic Surgery...................................................18

Histology and Embryology...........................................4

Neurosurgery...............................................................21

Anatomy........................................................................4

Dentistry & Oral Surgery............................................21

Molecular Pathophysiology..........................................5

Urology.......................................................................22

Molecular Cellular Physiology.....................................5

Ophthalmology...........................................................23

Molecular Pharmacology..............................................5

Otorhinolaryngology...................................................23

Pathology......................................................................5

Obstetrics and Gynecology.........................................23

Pathobiology.................................................................5

Anesthesiology and Resuscitology.............................24

Microbiology and Immunology....................................6

Plastic and Reconstructive Surgery............................25

Molecular and Cellular Immunology............................6

Laboratory Medicine...................................................25

Medical Genetics..........................................................6

Emergency and Critical Care Medicine......................27

Preventive Medicine and Public Health........................7

Comprehensive Cancer Therapy.................................27

Legal Medicine.............................................................7

Child and Adolescent Developmental Psychiatry.......29

Regenerative Medicine.................................................8

Infection and Host Defense.........................................29

Medicine I (Respirology Infectious Disease

Drug Discovery Science.............................................29& Allergology)...........................................................8
Medicine II (Gastroenterology Nephrology

Brain Disease Research...............................................29
Innovation of Medical and Health Sciences

Hematology)..............................................................8

Research..................................................................29

Medicine III (Neurology and Rheumatology)............11

Hearing Implant Sciences...........................................29

Medicine IV (Diabetes,Endocrinology andRehabilitation Center..................................................30

Metabolism).............................................................12Center for Medical Genetics.......................................30

Medicine V (Cardiovascular)......................................13

Department of Pharmacy............................................31

Psychiatry....................................................................14

Clinical Resident Training Center...............................31

Pediatrics.....................................................................15

Medical Safety Management Room............................31

Dermatology...............................................................16

Division of Animal Research......................................31

Radiology....................................................................17

Division of Radioisotope Experiments.......................31

Division of Gastroenterological, Hepato-Biliary-Pancreatic,

2

3

Aging Biology
20190001
Dai J, Ding X, Miyahara H, Xu Z, Cui X,
Igarashi Y, Sawashita J, Mori M, Higuchi K : Suppressionof mouse AApoAII amyloidosis progression by daily
supplementation with oxidative stress inhibitors. Oxid. Med.
Cell. Longev 2019: 1263274, 2019.

Molecular Pathology
20190002
Yamanoi M, Fujii C, Yamanoi K, Fukuda MN,
Nakayama J : Annexin A1 expression is correlated withmalignant potential of renal cell carcinoma. Int J Urol 26:
284-290, 2019.
20190003
Hirose T, Takahashi N, Tangkawattana P,
Minaguchi J, Mizumoto S, Yamada S, Miyake N, Hayashi
S, Hatamochi A, Nakayama J, Yamaguchi T, Hashimoto A,
Nomura Y, Takehana K, Kosho T, Watanabe T : Structural
alteration of glycosaminoglycan side chains and spatial
disorganization of collagen networks in the skin of patientswith mcEDS-CHST14. Biochim Biophys Acta Gen Subj
1863: 623-631, 2019.
20190004
Wang X, Tanaka N, Hu X, Kimura T, Lu Y, Jia
F, Sato Y, Nakayama J, Moriya K, Koike, K, Aoyama T :A high-cholesterol diet promotes steatohepatitis and liver
tumorigenesis in HCV core gene transgenic mice. Arch
Toxicol 93: 1713-1725, 2019.
20190005
Kawakubo M, Komura H, Goso Y, Okumura
M, Sato Y, Fujii C, Miyashita M, Arisaka N, Harumiya S,
Yamanoi K, Yamada S, Kakuta S, Kawashima H, Fukuda
MN, Fukuda M, Nakayama J : Analysis of A4gnt knockout
mice reveals an essential role for gastric sulfomucins inpreventing gastritis cystica profunda. J Histochem Cytochem
67: 759-770, 2019.
20190006
Sanjo H, Nakayama J, Yoshizawa T, Fehling
HJ, Akira S, Taki S : TAK1 safeguards macrophages against
proinflammatory cell death. J Immunol 203: 783-788, 2019.
20190007
Ida K, Yamanoi K, Asaka S, Takeuchi H,
Miyamoto T, Shiozawa T, Nakayama J : αGlcNAc and its
catalyst α4GnT are diagnostic and prognostic markers inuterine cervical tumor, gastric type. Sci Rep 9: 13043, 2019.
20190008
Desamero MJ, Kakuta S, Tang Y, Chambers JK,
Uchida K, Estacio MA, Cervancia C, Kominami Y, Ushio H,
Nakayama J, Nakayama H, Kyuwa S : Tumor-suppressing
potential of stingless bee propolis in in vitro and in vivo
models of differentiated-type gastric adenocarcinoma. Sci

Rep 9: 19635, 2019.

Metabolic Regulation
20190009
Wang X, Tanaka N, Hu X, Kimura T, Lu Y, Jia
F, Sato Y, Nakayama J, Moriya K, Koike K, Aoyama T :A high-cholesterol diet promotes steatohepatitis and liver
tumorigenesis in HCV core gene transgenic mice. Arch
Toxicol 93: 1713-1725, 2019.
20190010
Lu Y, Harada M, Kamijo Y, Nakajima T, Tanaka
N, Sugiyama E, Kyogashima M, Gonzalez FJ, Aoyama T :Peroxisome proliferator-activated receptor α attenuates highcholesterol diet-induced toxicity and pro-thrombotic effects
in mice. Arch Toxicol 93: 149-161, 2019.
20190011
Guo R, Hu X, Yamada Y, Harada M, Nakajima
T, Kashihara T, Yamada M, Aoyama T, Kamijo Y : Effectsof hypertension and antihypertensive treatments on sulfatide
levels in serum and its metabolism. Hypertens Res 42: 598609, 2019.
20190012
Yamada Y, Harada M, Hashimoto K, Guo R,
Nakajima T, Kashihara T, Yamada M, Aoyama T, Kamijo Y: Impact of chronic kidney dysfunction on serum sulfatides
and its metabolic pathway in mice. Glycoconj J 36: 1-11,
2019.
20190013
Tanaka N, Kimura T, Fujimori N, Nagaya
T, Komatsu M, Tanaka E : Current status, problems, andperspectives of non-alcoholic fatty liver disease research.
World J Gastroenterol 25: 163-177, 2019.
20190014
Wang BL, Zhang CW, Wang L, Tang KL,
Tanaka N, Gonzalez FJ, Xu Y, Fang ZZ : Lipidomics reveal
aryl hydrocarbon receptor (Ahr)-regulated lipid metabolic
pathway in alpha-naphthyl isothiocyanate (ANIT)-induced
intrahepatic cholestasis. Xenobiotica 49: 591-601, 2019.
20190015
S a t o M , H o r i u c h i A , Ta m a k i M , I c h i s e
Y, Kajiyama M, Yamamoto Y, Tanaka N : Safety andeffectiveness of nurse-administered propofol sedation in
outpatients undergoing gastrointestinal endoscopy. Clin
Gastroenterol Hepatol 17: 1098-1104, 2019.
20190016
Horiuchi A, Sakai R, Tamaki M, Kajiyama M,
Tanaka N, Morikawa A : Gastric emptying of elemental
liquid diets versus semisolid diets in bedridden gastrostomyfed patients. J Clin Gastroenterol 53: 373-378, 2019.
20190017
Kimura T, Tanaka N, Tanaka E : What will
happen in patients with advanced nonalcoholic fatty liverdisease. HepatoBiliary Surg Nutr 8: 283-285, 2019.

4

20190018
Horiuchi A, Ikuse T, Tanaka N : Cold snare
polypectomy: indications, devices, techniques, outcomes andfuture. Dig Endosc 31: 372-377, 2019.
20190019
Wakabayashi SI, Kimura T, Tanaka N, Komatsu
M, Tanaka E : Red plasma and ascites under ultraviolet A.
Lancet Gastroenterol Hepatol 4: 324-324, 2019.

Cardiovascular Research
20190020
Yamauchi A, Kamiyoshi A, Sakurai T, Miyazaki
H, Hirano E, Lim HS, Kaku T, Shindo T. : Placental
extract suppresses cardiac hypertrophy and fibrosis in anangiotensin II-induced cachexia model in mice . Heliyon. 5:
e02655, 2019.
20190021
Yamauchi A, Tone T, Sugimoto K, Lim HS,
Kaku T, Tohda C, Shindo T, Tamada K, Mizukami Y, Hirano
E. : Porcine placental extract facilitates memory and learningin aged mice . Food Sci Nutr. 7: 2995-3005, 2019.
20190022
Matsui S, Tanaka M, Kamiyoshi A, Sakurai
T, Ichikawa-Shindo Y, Kawate H, Dai K, Cui N, Wei Y,
Tanaka M, Kakihara S, Nakamura K, Yamauchi A, Ishida K,
Tanaka S, Kawamata M, Shindo T. : Endogenous calcitonin
gene-related peptide deficiency exacerbates postoperative
lymphedema by suppressing lymphatic capillary formationand M2 macrophage accumulation. Am J Pathol. 189: 24872502, 2019.
20190023
Yamauchi A. Kamiyoshi A, Sakurai T, Miyazaki
H, Hirano E, Lim HS, Kaku T, Shindo T. : Developmentof a mouse iron overload-induced liver injury model andevaluation of the beneficial effects of placenta extract oniron metabolism. Heliyon. 5: e01637, 2019.
20190024
Sakurai T, Kaimyoshi A, Takei N, Watanabe S,
Sato M, Shindo T. : Bindel-PCR: a novel and convenientmethod for identifying CRISPR/Cas9-induced biallelicmutants through modified PCR using Thermus aquaticus
DNA polymerase. Sci Rep. 9: 9923, 2019.
20190025
Hirabayashi K, Tanaka M, Imai A, Toriyama
Y, Iesato Y, Sakurai T, Kamiyoshi A, Ichikawa-Shindo Y,
Kawate H, Tanaka M, Dai K, Cui N, Wei Y, Nakamura
K, Iida S, Matsui S, Yamauchi A, Murata T, Shindo
T. : Development of a novel model of central retinal
vascular occlusion and the therapeutic potential of theadrenomedullin-RAMP2 system. Am J Pathol. 189: 449466, 2019.
20190026
Shindo T, Tanaka M, Kamiyoshi A, IchikawaShindo Y, Kawate H, Yamauchi A, Sakurai T. : Regulationof cardiovascular development and homeostasis by theadrenomedullin-RAMP system . Peptides. 111: 55-61, 2019.
20190027
S a k u r a i T, K a m i y o s h i A , O h t s u k a M ,Gurumurthy CB, Sato M, Shindo T. : Isolation andanalysis of a genome-edited single-hepatocyte from a Cas9transgenic mouse line. In: Liu C, Du Y (eds.). Methods in
Molecular Biology. Berlin: Springer; 2019. p.257-271.

Sports Medical Sciences
20190028
Masuki S, Morikawa M, Nose H : HighIntensity Walking Time Is a Key Determinant to Increase
Physical Fitness and Improve Health Outcomes After
Interval Walking Training in Middle-Aged and Older People.
Mayo Clin Proc 94(12): 2415-2426, 2019.

Histology and Embryology
20190029
Hirashima K, Yue F, Kobayashi M, Uchida
Y, Nakamura S, Tomotsune D, Matsumoto K, TakizawaShirasawa S, Yokoyama T, Kanno H, Sasaki K : Cell
biological profiling of reprogrammed cancer stem cell-likecolon cancer cells maintained in culture. Cell Tissue Res
375: 697-707, 2019.
20190030
Shigemura T, Matsuda K, Kurata T, Sakashita
K, Okuno Y, Muramatsu H, Yue F, Ebihara Y, Tsuji K,
Sasaki K, Nakahata T, Nakazawa Y, Koike K : Essential
role of PTPN11 mutation in enhanced haematopoietic
differentiation potential of induced pluripotent stem cells ofjuvenile myelomonocytic leukaemia. Br J Haematol 187:
163-173, 2019.

Anatomy20190031
Karasawa M, Yokouchi K, Kawagishi K,
Moriizumi T, Fukushima N : Effects of various lengths of
hypoglossal nerve resection on motoneuron survival. J Clin
Neurosci 60: 128-131, 2019.
20190032
Kakegawa A, Mori Y, Tsuchiya A, Sumitomo
N, Fukushima N, Moriizumi T : Independent Attachmentof Lateral Ankle Ligaments: Anterior Talofibular andCalcaneofibular Ligaments - A Cadaveric Study. J Foot
Ankle Surg 58: 717-722, 2019.
20190033
Tensho K, Iwaasa T, Koyama S, Yoshida K,
Shimodaira H, Horiuchi H, Kato H, Saito N, Fukushima N: The interrelationship between anterior cruciate ligament
tibial footprint and anterolateral meniscal root insertions:
Quantitative, morphological and positional analyses using
three-dimensional computed tomography images. Knee 26:5969-977, 2019.

Molecular Pathophysiology
20190034
Shih, C.M., Lin, F.Y., Yeh, J.S., Lin, Y.W., Loh,
S.H., Tsao, N.W., Nakagami, H., Morishita, R., Sawamura,T., Li, C.Y., Lin, C.Y. and Huang, C.Y. : Dysfunctional highdensity lipoprotein failed to rescue the function of oxidized
low density lipoprotein-treated endothelial progenitor cells:
a novel index for the prediction of HDL functionality. Transl
Res 205: 17-32, 2019.
20190035
Kakino, A., Usami, Y., Horiuchi, S., Fujita, Y.,
Kotani, K., Chen, C.H., Okamura, T. and Sawamura, T. : A
novel cell-free, non-fluorescent method to measure LOX-1binding activity corresponding to the functional activity of
HDL. J Atheroscler Thromb 26: 947-958, 2019.

Molecular Cellular Physiology
20190036
Mori T, Kasem EA, Suzuki-Kouyama E, Cao
X, Li X, Kurihara T, Uemura T, Yanagawa T, Tabuchi K. :Deficiency of calcium/calmodulin-dependent serine protein
kinase disrupts the excitatory-inhibitory balance of synapses
by down-regulating GluN2B. Mol Psychiatry. 24(7): 10791092, 2019.

Molecular Pharmacology
20190037
Yamada Y, Harada M, Hashimoto K, Guo R,
Nakajima T, Kashihara T, Yamada M, Aoyama T,Kamijo Y: Impact of chronic kidney dysfunction on serum sulfatides
and its metabolic pathway in mice. Glycoconj J 36: 1-11,
2019.
20190038
Guo R, Hu X, Yamada Y, Harada M, Nakajima
T, Kashihara T, Yamada M, Aoyama T, Kamijo Y : Effectsof hypertension and antihypertensive treatments on sulfatide
levels in serum and its metabolism. Hypertens Res 42: 598609, 2019.
20190039
Zhang H, Kashihara T, Nakada T, Tanaka S,
Ishida K, Fuseya S, Kawagishi H, Kiyosawa K, Kawamata
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20190041
Kustiarini DA, Nishigaki T, Kanno H, To H :Effects of Morinda citrifolia on rheumatoid arthritis in SKG
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20190042
Hirashima K, Yue F, Kobayashi M, Uchida
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20190043
Hardian RF, Goto T, Kuwabara H, Hanaoka
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Ichimata S, Kobayashi M, Ohya M, Otsuki T,
Yanagisawa K, Tateishi K, Kato A, Matsuo A, Kanno H : A
fulminant case of classical Hodgkin lymphoma: A diagnostic
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20190045
Ohya M, Kobayashi M, Sozuki T, Kanno H,
Nakazawa K : Malignant peritoneal mesothelioma diagnosed
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20190046
Yamamoto Y, Tsuzuki T, Akatsuka J, Ueki M,
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Pathobiology

Pathology

20190047
Mikawa S, Kondo M, Kaji N, Mihara T,
Yoshitake R, Nakagawa T, Takamoto M, Nishimura R,
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20190040
Ohya M, Nakazawa K, Kanno H : Lower
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20190048
Mitsunaga T, Norose K, Aosai F, Horie H,
Ohnuma N, Yano A. : Infection dynamics of Toxoplasma
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Microbiology and Immunology
20190049
Amano Y., Akazawa K., Yasuda J., YoshinoK., Kojima K., Kobayashi K., Matsuzaki S., Nakasaki
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Molecular and Cellular Immunology
20190050
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20190051
Hayashi K, Itoh S, Morikawa A, Onozaki K,
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Okubo Y, Tokumaru S, Yamamoto Y, Miyagawa
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Kobayashi M, Kitano T, Nishiyama S, Sanjo
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20190054
Sanjo H, Nakayama J, Yoshizawa T, Fehling HJ,Akira S, Taki S. : TAK1 Safeguards Macrophages against
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2019.

Medical Genetics
20190055
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M, Motobayashi M, Kawamura R, Wakui K, Nishi E,
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20190056
Ogawa Y, Nakamura K, Ezawa N, Yamaguchi
T, Yoshinaga T, Miyazaki D, Kosho T, Sekijima T. : A novel
CACNA1A nonsense variant in a patient presenting withparoxysmal exertion-induced dyskinesia. J Neurol Sci. 399:
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20190057
Hirose T, Takahashi N, Tangkawattana P,
Minaguchi J, Mizumoto S, Yamada S, Miyake N, Hayashi
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20190059
Yokota Y, Moteki H, Nishio SY, Yamaguchi T,
Wakui K, Kobayashi Y, Ohyama K, Miyazaki H, Matsuoka
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20190060
Yamasaki M, Abe K, Kosho T, Yamaguchi T.
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7

20190061
Sado T, Nakayama Y, Kato S, Homma H,
Kusakari M, Hidaka N, Gomi S, Takamizawa S, Kosho
T, Saito S, Sugano K : Extremely young case of small
bowel intussusception due to Peutz-Jeghers syndrome with
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20190062
Uehara M, Nakamura Y, Takahashi J, Suzuki T,
Iijima M, Arakawa Y, Ida K, Kosho T, Kato H. : Efficacy ofdenosumab therapy for a 21-year-old woman with PraderWilli syndrome, osteoporosis and history of fractures: a casereport. Ther Clin Risk Manag. 15: 303-307, 2019.
20190063
Sugiyama K, Moteki H, Kitajiri SI, Kitano T,
Nishio SY, Yamaguchi T, Wakui K, Abe S, Ozaki A, Motegi
R, Matsui H, Teraoka M, Kobayashi Y, Kosho T, Usami SI.
: Mid-Frequency Hearing Loss Is Characteristic ClinicalFeature of OTOA-Associated Hearing Loss. Genes (Basel).
10: 715, 2019.
20190064
Oda Y, Uchiyama Y, Motomura A, Fujita A,
Azuma Y, Harita Y, Mizuguchi T, Yanagi K, Ogata H,
Hata K, Kaname T, Matsubara Y, Wakui K, Matsumoto
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M, White SM, Matsuo M, Saito K, Phadke S, Kosho T,
Yap P, Goyal M, Clarke LA, Sachdev R, McGillivray G,
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Ohashi H, Shimizu K, Nagasaki K, Hamada J, Dateki S,
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Matsuoka T, Shimoji Y, Tan TY, Kapoor S, Gregersen N,
Rossi M, Marie-Laure M, McGregor L, Oishi K, Mehta
L, Gillies G, Lockhart PJ, Pope K, Shukla A, Girisha KM,
Abdel-Salam GMH, Mowat D, Coman D, Kim OH, CordierMP, Gibson K, Milunsky J, Liebelt J, Cox H, El Chehadeh
S, Toutain A, Saida K, Aoi H, Minase G, Tsuchida N, Iwama
K, Uchiyama Y, Suzuki T, Hamanaka K, Azuma Y, Fujita A,
Imagawa E, Koshimizu E, Takata A, Mitsuhashi S, Miyatake
S, Mizuguchi T, Miyake N, Matsumoto N. : Genetic
abnormalities in a large cohort of Coffin-Siris syndrome
patients. J Hum Genet. 64: 1173-1186, 2019.

Gaku Ichihara, Masayuki Ikeda, Akiyoshi Ito, Yuki Ito,
Satoko Iwasawa, Takeyasu Kakumu, Michihiro Kamijima,
Kanae Karita, Takahiko Katoh, Toshio Kawai, Toshihiro
Kawamoto, Shinji Kumagai, Yukinori Kusaka, Akiko
Matsumoto, Muneyuki Miyagawa, Hiroyuki Miyauchi,
Yasuo Morimoto, Kasuke Nagano, Hisao Naito, Tamie
Nakajima, Makiko Nakano, Tetsuo Nomiyama, Hirokazu
Okuda, Masayuki Okuda, Kazuyuki Omae, Haruhiko
Sakurai, Kazuhiro Sato, Tomotaka Sobue, Yasushi
Suwazono, Toru Takebayashi, Tatsuya Takeshita, Akito
Takeuchi, Ayano Takeuchi, Masatoshi Tanaka, Shigeru
Tanaka, Teruomi Tsukahara, Masashi Tsunoda, Susumu
Ueno, Jun Ueyama, Yumi Umeda, Kenya Yamamoto, Yuko
Yamano, Takenori Yamauchi, Eiji Yano : Occupationale x p o s u r e l i m i t s f o r c u m e n e , 2,4- d i c h l o r o p h e n o x yacetic acid, silicon carbide whisker, benzyl alcohol, andmethylamine, and carcinogenicity, occupational sensitizer,
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20190067
S a t o s h i O h i r a , N o r i k o M o t o k i , Ta k u m i
Shibazaki, Yuka Misawa, Yuji Inaba, Makoto Kanai,
Hiroshi Kurita, Tanri Shiozawa, Yozo Nakazawa, Teruomi
Tsukahara, Tetsuo Nomiyama & The Japan Environment& Children’s Study (JECS) Group : Alcohol Consumption
During Pregnancy and Risk of Placental Abnormality: The
Japan Environment and Children’s Study. Scientific Reports
9: 10259, 2019.
20190068
Noriko Motoki, Yuji Inaba, Takumi Shibazaki,
Yuka Misawa, Satoshi Ohira, Makoto Kanai, Hiroshi
Kurita, Yozo Nakazawa, Teruomi Tsukahara, Tetsuo
Nomiyama & The Japan Environment & Children’s Study(JECS) Group : Maternal Exposure to Housing Renovation
During Pregnancy and Risk of Offspring with Congenital
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Scientific Reports 9: 11564, 2019.
20190069
Hirotsugu Oda, Momoko Miyakawa, Masaru
Mizuki, Yuka Misawa, Teruomi Tsukahara, Miyuki
Tanaka, Koji Yamauchi, Fumiaki Abe, Tetsuo Nomiyama: Effects of Lactoferrin on Subjective Skin Conditions
in Winter: A Preliminary, Randomized, Double-Blinded,
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Preventive Medicine and Public Health

Legal Medicine

20190066
Committee for Recommendation ofO c c upati onal E xpos ure Li mi t s , J ap a n S o c ie ty f o r
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Harada, Hajime Hori, Seichi Horie, Masayoshi Ichiba,

20190070
Shiozaki T, Sato N, Hayashi T, Kobayashi
K, Asamura H : Wild-type ATTR amyloidosis may be
associated with unexpected death among the elderly. Leg
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8

Regenerative Medicine
20190071
Okano S, Shiba Y : Therapeutic Potential of
Pluripotent Stem Cells for Cardiac Repair after Myocardial
Infarction. Biol Pharm Bull 42: 524-530, 2019.
20190072
Kadota S, Shiba Y : Pluripotent Stem CellDerived Cardiomyocyte Transplantation for Heart Disease
Treatment. Curr Cardiol Rep 21: 73, 2019.
20190073
Sato M, Shiba N, Miyazaki D, Shiba Y,
Echigoya Y, Yokota T, Takizawa H, Aoki Y, Takeda S,
Nakamura A : Amelioration of intracellular Ca 2+ regulation
by exon-45 skipping in Duchenne muscular dystrophyinduced pluripotent stem cell-derived cardiomyocytes.
Biochem Biophys Res Commun 520: 179-185, 2019.

Medicine I(Respirology, Infectious Disease & Allergology)
20190074
Kazunari Tateishi , Ryo Ko, Takehito Shukuya, Yusuke Okuma , Satoshi Watanabe , Shoichi Kuyama ,Kyoko Murase , Yoko Tsukita , Hironori Ashinuma , Taku
Nakagawa , Kazutsugu Uematsu , Mika Nakao , Yoshiaki
Mori , Kyoichi Kaira , Atsuto Mouri , Takao Miyabayashi, Hiroyuki Sakashita , Yoko Matsumoto , Tomoyuki
Tanigawa , Tomonobu Koizumi , Satoshi Morita , Kunihiko
Kobayashi, Toshihiro Nukiwa , Kazuhisa Takahashi , North
East Japan Study Group : Clinical Outcomes of Second-Line
Chemotherapy in Patients with Previously Treated Advanced
Thymic Carcinoma: A Retrospective Analysis of 191
Patients from the NEJ023 Study. Oncologist 25: e668-e674,
2019.
20190075
Yasuo M, Droma Y, Kitaguchi Y, Ito M,
Imamura H, Kawakubo M, Hanaoka M. : The relationshipbetween acrolein and oxidative stress in COPD: in systemic
plasma and in local lung tissue. Int J Chron Obstruct Pulmon
Dis 14: 1527-1537, 2019.
20190076
Sonehara K, Tateishi K, Komatsu M, Yamamoto
H, Hanaoka M, Kanda S, Koizumi T. : Modified Glasgow
Prognostic Score as a Prognostic Factor in Patients with
Extensive Disease-Small-Cell Lung Cancer: A Retrospective
Study in a Single Institute. Chemotherapy 64: 129-137,
2019.
20190077
Ikuyama Y, Ushiki A, Akahane J, Kosaka M,
Kitaguchi Y, Urushihata K, Yasuo M, Yamamoto H, Hanaoka
M. : Comparison of clinical characteristics of patientswith Mycobacterium avium complex disease by gender.
Epidemiol Infect 147: 108, 2019.

20190078
Nishie K, Yamamoto S, Yamaga T, Horigome N,
Hanaoka M. : Peripherally acting μ-opioid antagonist for thetreatment of opioid-induced constipation: Systematic review
and meta-analysis. J Gastroenterol Hepatol 34: 818-829,
2019.
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K o m a t s u M , Ya m a m o t o H , S h o m u r a T,
Sonehara K, Ichiyama T, Urushihata K, Ushiki A, Yasuo
M, Wakamatsu T, Sugimoto S, Oto T, Date H, Koizumi T,
Hanaoka M, Kubo K. : Twenty-year Follow-up of the First
Bilateral Living-donor Lobar Lung Transplantation in Japan.
Intern Med 58: 3133-3137, 2019.
20190080
Yamamoto H, Yasuo M, Komatsu M, Ushiki
A, Hamano H, Hori A, Nakajima T, Uehara T, Fujinaga
Y, Matsui S, Hanaoka M. : Comparison of the chemokine
profiles in the bronchoalveolar lavage fluid between IgG4related respiratory disease and sarcoidosis: CC-chemokine
ligand 1 might be involved in the pathogenesis ofsarcoidosis. Cytokine 120: 125-129, 2019.
20190081
Sonehara K, Tateishi K, Fukushima T, Komatsu
M, Yamamoto H, Koizumi T, Hanaoka M. : The efficacy ofamrubicin third-line chemotherapy in patients with relapsed
extensive-disease small-cell lung cancer: A retrospective andhistorical study in a single institute. Thorac Cancer 10: 18051811, 2019.

Medicine II(Gastroenterology Nephrology Hematology)
20190082
Guo R, Hu X, Yamada Y, Harada M, Nakajima
T, Kashihara T, Yamada M, Aoyama T, Kamijo Y : Effectsof hypertension and antihypertensive treatments on sulfatide
levels in serum and its metabolism. Hypertens Res 42: 598609, 2019.
20190083
Harada M, Ishii W, Masubuchi T, Ichikawa T,
Kobayashi M : Relationship Between Immunosuppressive
Therapy and the Development of Infectious Complications
Among Patients with Anti-neutrophil Cytoplasmic Antibodyassociated Vasculitis: A Single-center, Retrospective
Observational Study. Cureus 11: e5676, 2019.
20190084
Harada M, Ooki M, Kohashi K, Ichikawa
T, Kobayashi M : Clinical Survey of Decreased Blood
Flow Rate in Continuous Renal Replacement Therapy: A
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Honda A, Tanaka A, Kaneko T, Komori A, Abe
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9S, Umemura T, Sato K, Kaneko A, Kikuchi K, Itakura J,
Nomura T, Kakisaka K, Fujii H, Kawada N, Takikawa
Y, Masaki T, Ohira H, Mochida S, Yoshiji H, Iimuro S,
Matsuzaki Y, Takikawa H, Japan, P. B. C. Study Group :Bezafibrate Improves GLOBE and UK-PBC Scores andLong-Term Outcomes in Patients With Primary Biliary
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20190086
Ito T, Kawa S, Matsumoto A, Kubota K,
Kamisawa T, Okazaki K, Hirano K, Hirooka Y, Uchida K,
Masuda A, Ohara H, Shimizu K, Arakura N, Masamune A,
Kanno A, Sakagami J, Itoi T, Ito T, Ueki T, Nishino T, Inui
K, Mizuno N, Yoshida H, Sugiyama M, Iwasaki E, Irisawa
A, Shimosegawa T, Chiba T : Risk Factors for Pancreatic
Stone Formation in Type 1 Autoimmune Pancreatitis: A
Long-term Japanese Multicenter Analysis of 624 Patients.
Pancreas 48: 49-54, 2019.
20190087
Joshita S, Umemura T, Yamashita Y, Sugiura
A, Yamazaki T, Fujimori N, Matsumoto A, Tanaka E :Biochemical and plasma lipid responses to pemafibrate inpatients with primary biliary cholangitis. Hepatol Res 49:
1236-1243, 2019.
20190088
Kako S, Joshita S, Matsuo A, Kawaguchi K,
Umemura T, Tanaka E : A Case of Adult T-Cell Leukemia/
Lymphoma Complicated with Bilateral Chylothorax. Case
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20190089
Kanno T, Kanno Y, Shiroi K, Kobayashi N,
Matsushita N, Kamishima K, Hashimoto K, Kamijo Y :Features of high flow access in the elderly. J Vasc Access 20:
71-75, 2019.
20190090
Kawakami T, Sekiguchi N, Kobayashi J,
Yamane T, Nishina S, Sakai H, Hirabayashi Y, Nakazawa
H, Ishida F : STAT3 mutations in natural killer cells
are associated with cytopenia in patients with chronic
lymphoproliferative disorder of natural killer cells. Int J
Hematol 109: 563-571, 2019.
20190091
Kimura T, Tanaka N, Tanaka E : What will
happen in patients with advanced nonalcoholic fatty liverdisease? Hepatobiliary Surg Nutr 8: 283-285, 2019.
20190092
Kishida M, Yamada Y, Inayama E, Kitamura
M, Nishino T, Ota K, Shintani A, Ikenoue T : Effectivenessof music therapy for alleviating pain during haemodialysis
access cannulation for patients undergoing haemodialysis:
a multi-facility, single-blind, randomised controlled trial.
Trials 20: 631, 2019.
20190093

K o b a y a s h i S , J o s h i t a S , Ya m a m o t o C ,Yanagisawa T, Miyazawa T, Miyazawa M, Kubota D, SatoJ, Umemura T, Tanaka E : Efficacy and safety of eradication
therapy for elderly patients with helicobacter pylori
infection. Medicine (Baltimore) 98: e16619, 2019.
20190094
Konuma T, Kondo T, Kawata T, Iwato K, Sato
Y, Mori T, Ohashi K, Nakazawa H, Sugahara H, Ago H,
Eto T, Imamura Y, Fukuda T, Kanda Y, Atsuta Y, Yano S,
Adult Acute Myeloid Leukemia Working Group of theJapan Society for Hematopoietic Cell, Transplantation :Hematopoietic Cell Transplantation for Acute Panmyelosis
with Myelofibrosis: A Retrospective Study in Japan. Biol
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20190095
Kuraishi Y, Uehara T, Kobayashi Y, Nakajima
T, Watanabe T, Shimizu A, Ota H, Tanaka E : Correlationof clinicopathological features and leucine-rich repeatcontaining G-protein-coupled receptor 5 expression inpancreatic ductal adenocarcinoma. Pathol Res Pract 215:
152623, 2019.
20190096
Kuraishi Y, Muraki T, Ashihara N, Ozawa
M, Nakamura A, Watanabe T, Ito T, Hamano H, Kawa S :Validity and safety of endoscopic biliary stenting for biliary
stricture associated with IgG4-related pancreatobiliary
disease during steroid therapy. Endosc Int Open 7:
E1410-E1418, 2019.
20190097
Kuraishi Y, Watanabe T, Muraki T, Ashihara
N, Ozawa M, Nakamura A, Kanai K, Hamano H, Kawa
S : Effectiveness of steroid therapy for pancreatic cysts
complicating autoimmune pancreatitis and management
strategy for cyst-related complications. Scand J
Gastroenterol 54: 773-779, 2019.
20190098
Kurihara S, Harada M, Ichikawa T, Ehara T,
Kobayashi M : Nephrotic Syndrome due to Focal Segmental
Glomerulosclerosis Complicating Sjögren's Syndrome: A
Case Report and Literature Review . Case Rep Rheumatol
2019: 1749795, 2019.
20190099
Mizuno S, Kawamura K, Hanamura I, Sunami
K, Mori T, Nakamura F, Iida S, Nakazawa H, Makita M,
Kako S, Sawa M, Ueda Y, Takahashi H, Kanda Y, Ichinohe
T, Atsuta Y, Takamatsu H, Takami A : Efficacy and safetyof autologous stem cell transplantation in patients aged ≥65 years with multiple myeloma in the era of novel agents .
Bone Marrow Transplant 54: 1595-1604, 2019.
20190100
Lu Y, Harada M, Kamijo Y, Nakajima T, Tanaka
N, Sugiyama E, Kyogashima M, Gonzalez FJ, Aoyama T :Peroxisome proliferator-activated receptor alpha attenuates
high-cholesterol diet-induced toxicity and pro-thrombotic

10

effects in mice. Arch Toxicol 93: 149-161, 2019.
20190101
Nihei T, Kiniwa Y, Mikoshiba Y, Joshita S,
Okuyama R : Improvement of porphyria cutanea tarda
following treatment of hepatitis C virus by direct-acting
antivirals: A case report. J Dermatol 46: e149-e151, 2019.
20190102
S a i t o T, Ta n a k a M , M a t s u d a K , H o n m a
H, Komori K, Morita D, Nakazawa H, Yanagisawa R,
Nakazawa Y : Significance of Molecular Monitoring of T
Cells for the Decision of Treatment Strategy for Epstein-Barr
Virus-associated Hemophagocytic Lymphohistiocytosis. J
Pediatr Hematol Oncol 41: 407-409, 2019.
20190103
Shimizu I, Nakazawa H, Sato Y, Wolfhagen I,
Konings KD : Does blended problem-based learning make
Asian medical students active learners? : a prospective
comparative study. BMC Med Educ 19: 147, 2019.
20190104
Shimomura Y, Hara M, Tachibana T, Ohashi
K, Sakura T, Fukuda T, Nakazawa H, Iwato K, Kanda Y,
Ikeda T, Eto T, Kanda J, Ichinohe T, Atsuta Y, Ishikawa T,
Ishiyama K : Outcomes of second allogeneic haematopoietic
stem cell transplantation in patients with relapse of
myelodysplastic syndrome. Br J Haematol 186: 86-90, 2019.
20190105
Suga T, Ito A, Ota H, Tateiwa N, Matsumoto
A, Tanaka E : Response to the letter by Matsushita et al.
regarding our manuscript "Resection Depth and Layer
of Cold Snare Polypectomy versus Endoscopic Mucosal
Resection". J Gastroenterol 54: 473, 2019.
20190106
Takamatsu H, Yamashita T, Kurahashi S, Saitoh
T, Kondo T, Maeda T, Nakazawa H, Murata M, Narita T,
Kuroda J, Hashimoto H, Kawamura K, Miyamoto T, Honda
S, Ichinohe T, Atsuta Y, Sunami K : Clinical Implicationsof t(11;14) in Patients with Multiple Myeloma Undergoing
Autologous Stem Cell Transplantation. Biol Blood Marrow
Transplant 25: 474-479, 2019.
20190107
Tanaka N, Kimura T, Fujimori N, Nagaya
T, Komatsu M, Tanaka E : Current status, problems, andperspectives of non-alcoholic fatty liver disease research.
World J Gastroenterol 25: 163-177, 2019.
20190108
Umemura T, Joshita S, Shibata S, Sugiura A,
Yamazaki T, Fujimori N, Matsumoto A, Tanaka E : Renal
impairment is associated with increased risk of mortality
in patients with cirrhosis: A retrospective cohort study.
Medicine (Baltimore) 98: e14475, 2019.
20190109
Umemura T, Joshita S, Saito H, Yoshizawa K,
Norman GL, Tanaka E, Ota M : KIR/HLA genotypes confer

susceptibility and progression in patients with autoimmune
hepatitis. JHEP Rep 1: 353-360, 2019.
20190110
Hitomi Y, Ueno K, Kawai Y, Nishida N, Kojima
K, Kawashima M, Aiba Y, Nakamura H, Kouno H, Kouno
H, Ohta H, Sugi K, Nikami T, Yamashita T, Katsushima S,
Komeda T, Ario K, Naganuma A, Shimada M, Hirashima
N, Yoshizawa K, Makita F, Furuta K, Kikuchi M, Naeshiro
N, Takahashi H, Mano Y, Yamashita H, Matsushita K,
Tsunematsu S, Yabuuchi I, Nishimura H, Shimada Y,
Yamauchi K, Komatsu T, Sugimoto R, Sakai H, Mita E,
Koda M, Nakamura Y, Kamitsukasa H, Sato T, Nakamuta M,
Masaki N, Takikawa H, Tanaka A, Ohira H, Zeniya M, Abe
M, Kaneko S, Honda M, Arai K, Arinaga-Hino T, Hashimoto
E, Taniai M, Umemura T, Joshita S, Nakao K, Ichikawa
T, Shibata H, Takaki A, Yamagiwa S, Seike M, Sakisaka
S, Takeyama Y, Harada M, Senju M, Yokosuka O, Kanda
T, Ueno Y, Ebinuma H, Himoto T, Murata K, Shimoda S,
Nagaoka S, Abiru S, Komori A, Migita K, Ito M, Yatsuhashi
H, Maehara Y, Uemoto S, Kokudo N, Nagasaki M,
Tokunaga K, Nakamura M : POGLUT1, the putative effector
gene driven by rs2293370 in primary biliary cholangitis
susceptibility locus chromosome 3q13.33. Sci Rep 9: 102,2019.
20190111
Umeshita K, Eguchi S, Egawa H, Haga H,
Kasahara M, Kokudo N, Sakisaka S, Takada Y, Tanaka
E, Eguchi H, Uemoto S, Ohdan H : Liver transplantationin Japan: Registry by the Japanese Liver Transplantation
Society. Hepatol Res 49: 964-980, 2019.
20190112
Wakabayashi SI, Kimura T, Tanaka N, Komatsu
M, Tanaka E : Red plasma and ascites under ultraviolet A.
Lancet Gastroenterol Hepatol 4: 324, 2019.
20190113
Wang X, Tanaka N, Hu X, Kimura T, Lu Y, Jia
F, Sato Y, Nakayama J, Moriya K, Koike K, Aoyama T :A high-cholesterol diet promotes steatohepatitis and liver
tumorigenesis in HCV core gene transgenic mice. Arch
Toxicol 93: 1713-1725, 2019.
20190114
Yamada Y, Inui K, Hara Y, Fuji K, Sonoda K,
Hashimoto K, Kamijo Y : Verification of serum albumin
elevating effect of cell-free and concentrated ascites
reinfusion therapy for ascites patients: a retrospective
controlled cohort study. Sci Rep 9: 10195, 2019.
20190115
Yamada Y, Harada M, Hashimoto K, Guo R,
Nakajima T, Kashihara T, Yamada M, Aoyama T, Kamijo Y: Impact of chronic kidney dysfunction on serum Sulfatides
and its metabolic pathway in mice. Glycoconj J 36: 1-11,
2019.

11

20190116
Yamanaka M, Yanagisawa R, Kojima S,
Nakazawa H, Shimodaira S : Investigation of factors
associated with allergic transfusion reaction due to platelettransfusion and the efficacy of platelets resuspended in
BRS-A in adult patients. Transfusion 59: 3405-3412, 2019.

Medicine III (Neurology and Rheumatology)
20190117
Buxbaum JN, Brannagan T 3rd, Buades-ReinésJ, Cisneros E, Conceicao I, Kyriakides T, Merlini G, Obici
L, Plante-Bordeneuve V, Rousseau A, Sekijima Y, Imai A,
Waddington Cruz M, Yamada M : Transthyretin depositionin the eye in the era of effective therapy for hereditary
ATTRV30M amyloidosis. Amyloid 26: 10-14, 2019.
20190118
Ichikawa T, Shimojima Y, Otuki T, Ueno
KI, Kishida D, Sekijima Y : Acquired Amegakaryocytic
Thrombocytopenia in Adult-onset Still's Disease: Successful
Combination Therapy with Tocilizumab and Cyclosporine.
Intern Med 58: 3473-3478, 2019.
20190119
Ichimata S, Aoyagi D, Yoshinaga T, Katoh
N, Kametani F, Yazaki M, Uehara T, Shiozawa S : A caseof spheroid-type localized lactoferrin amyloidosis in the
bronchus. Pathol Int 69: 235-240, 2019.
20190120
Ikeda SI, Hineno A, Yoshinaga T, Matsuo
K, Suga T, Shiina T, Otsuki T, Hoshii Y : Sjögren syndromerelated plasma cell disorder and multifocal nodular AL
amyloidosis: clinical picture and pathological findings.
Amyloid 26: 225-233, 2019.
20190121
Ikeda SI, Hineno A, Ichikawa T, Makino M :Tafamidis dramatically improved severe proteinuria in apatient with TTR V30M hereditary ATTR amyloidosis .
Amyloid 26: 99-100, 2019.
20190122
I s h i i T , S e k i j i m a Y, A n d o Y :Patient profile with ATTR-FAP and evaluation of the safety
and efficacy of tafamidis meglumine in Japan - interim
analysis in post-marketing surveillance. Amyloid 26: 45-46,
2019.
20190123
Ishikawa H, Shindo A, Ii Y, Kishida D, Niwa A,
Nishiguchi Y, Matsuura K, Kato N, Mizutani A, Tachibana
K, Hirata Y, Matsuyama H, Ogawa-Ito A, Taniguchi A,
Tomimoto H : MEFV gene mutations in neuro-Behçet'sdisease and neuro-Sweet disease. Ann Clin Transl Neurol 6:2595-2600, 2019.
20190124
Ishikawa H, Shindo A, Ii Y, Sakano S, Asahi
M, Matsuura K, Kishida D, Umino M, Maeda M, Tomimoto
H : Vertebral artery dissection associated with familial

mediterranean fever and Behc et’s disease. Ann Clin Transl
Neurol 6: 974-978, 2019.
20190125
Ito M. Nobata H, Imai H, Yoshino M, Banno S,
Ito Y, Ito H, Kishida D : Familial Mediterranean fever type
2 with heterozygous mutations of E148Q and M6941 in a
Japanese patient with progressive systemic AA amyloidosis.
Mod Rheumatol Case Rep 3: 79-85, 2019.
20190126
Kodaira M, Ohashi N, Morita H, Sekijima
Y : Length-dependent truncal Aδ-fiber dysfunction inhereditarytransthyretin amyloidosis: An intra-epidermal
electrical stimulationstudy. Clin Neurophysiol 130: 903-910,
2019.
20190127
Koyama J, Minamisawa M, Sekijima
Y, K u w a h a r a K , K a t s u y a m a T, M a r u y a m a K :Role of echocardiography in assessing cardiac amyloidoses:a systematic review. J Echocardiogr 17: 64-75, 2019.
20190128
Kozuka A, Koyama J, Sekijima Y, Ikeda U: Quantitative analysis of endocardial and epicardial left
ventricular myocardial deformation in patients with cardiac
amyloidosis. Shinshu Med J 67: 49-62, 2019.
20190129
Miyake Z, Nakamagoe K, Ezawa N, Yoshinaga
T, Hashimoto R, Sato T, Sekijima Y, Tamaoka : Late-onset
Transthyretin (TTR)-familial Amyloid Polyneuropathy(FAP) with a Long Disease Duration from Non-endemic
Areas in Japan. Intern Med 58: 713-718, 2019.
20190130
Ogawa Y, Nakamura K, Ezawa N, Yamaguchi
T, Yoshinaga T, Miyazaki D, Kosho T, Sekijima Y : A novel
CACNA1A nonsense variant in a patient presenting withparoxysmal exertion-induced dyskinesia. J Neurol Sci 399:
214-216, 2019.
20190131
Ohashi N, Kodaira M, Morita H, Sekijima Y :Electrophysiological demyelinating features in hereditary
ATTR amyloidosis. Amyloid 26: 15-23, 2019.
20190132
Sanjo N, Nose Y, Shishido-Hara Y, Mizutani
S, Sekijima Y, Aizawa H, Tanizawa T, Yokota T : A
controlled inflammation and a regulatory immune system
are associated with more favorable prognosis of progressive
multifocal leukoencephalopathy. J Neurol 266: 369-377,
2019.
20190133
Sato M, Kishida D, Miyazaki D, Sekijima
Y : A Patient with Limbic Encephalitis Associated with
Anti-leucine-rich Glioma-inactivated 1 (LGI1) Antibody
Presenting with Slowly Progressive Cognitive Impairment
and Fluctuating Striatal Lesions. Intern Med 58: 287-291,

12

2019.
20190134
Sato M, Shiba N, Miyazaki D, Shiba
Y, Echigoya Y, Yokota T, Takizawa H, Aoki Y, Takeda
S, Nakamura A : Amelioration of intracellular
Ca2+ regulation by exon-45 skipping in Duchenne
muscular dystrophy-induced pluripotent stem cell-derived
cardiomyocytes. Biochem Biophys Res Commun 520: 179185, 2019.
20190135
Sato M,Takizawa H, Nakamura A, Turner B
J, Shabanpoor F, Aoki Y : Application of Urine-Derived
Stem Cells to Cellular Modeling in Neuromuscular and
Neurodegenerative Diseases. Front Mol Neurosci 12: 297297, 2019.
20190136
Sekijima Y, Mundayat R, Ishii T, Ando Y : The
current status of the Transthyretin Amyloidosis Outcomes
Survey (THAOS) in Japan. Amyloid 26: 61-62, 2019.
20190137
Shimojima Y, Kishida D, Ueno KI, Ushiyama
S, Ichikawa T, Sekijima Y : Characteristics of Circulating
Natural Killer Cells and Their Interferon-γ Production in
Active Adult-onset Still Disease. J Rheumatol 46: 12681276, 2019.
20190138
Shintani Y, Okada A, Morita Y, Hamatani
Y, A m a n o M , Ta k a h a m a H , A m a k i M , H a s e g a w a
T, Ohta-Ogo K, Kanzaki H, Ishibashi-Ueda H, Yasuda
S, Shimazaki C, Yoshinaga T, Yazaki M, Sekijima Y, Izumi
C : Monitoring treatment response to tafamidis by serial
native T1 and extracellular volume in transthyretin amyloid
cardiomyopathy. ESC Heart Fail 6: 232-236, 2019.
20190139
Shirai T, Kiniwa Y, Sato R, Sano T, Nakamura
K, Mikoshiba Y, Ohashi N, Sekijima Y, Okuyama R :Presence of antibodies to striated muscle and acetylcholine
receptor in association with occurrence of myasthenia gravis
with myositis and myocarditis in a patient with melanoma
treated with an anti-programmed death 1 antibody. Eur J
Cancer 106: 193-195, 2019.
20190140
Tanaka N, Sakuraba H, Hiraga H, Mayama
K, Kikuchi H, Kishida D, Akemoto Y, Hasui K, Ota S,
Watanabe R, Murai Y, Maeda T, Kamata K, Tatsuta T,
Sawaya M, Chinda D, Mikami T, Yamagata K, Ishiguro
Y, Tanaka M, Fukuda S : Long-term maintenance of themucosal healing induced by azacitidine therapy in a patientwith intestinal Behçet's-like disease accompanied withmyelodysplastic syndrome involving trisomy 8. Immunol
Med 42: 135-141, 2019.
20190141

Watanabe R, Sakuraba H, Hiraga H, Kishida

D, Ota S, Hasui K, Kikuchi H, Akemoto Y, Tanaka N,
Maeda T, Murai Y, Yoshida S, Tatsuta T, Sawaya M,
Chinda D, Mikami T, Ishiguro Y, Fukuda S : Diagnosti
c approach for patients with unidentified fever according to the classical criteria of fever of unknown origin in
the field of autoimmune disorders. Immunol Med 42: 176184, 2019.
20190142
Y a m a d a Y, F u k u s h i m a T , K o d a m a
S, Shimizu H, Kakita A, Makino K, Sekijima Y :A case of cerebral amyloid angiopathy-type hereditary
ATTR amyloidosis with Y69H (p.Y89H) variant displaying
transient focal neurological episodes as the main symptom.
Amyloid 26: 251-252, 2019.
20190143
Yoshinaga T, Kurokawa T, Uehara T, Nitta J,
Horiuchi T, Sekijima Y : Optic neuropathy from connected
intra- and extraorbital lesions in IgG4-related disease.
Rinsho Shinkeigaku 59: 746-751, 2019.

Medicine IV(Diabetes,Endocrinology and Metabolism)20190144
Ohkubo Y, Sekido T, Nishio S, Sekido K,
Kitahara J, Suzuki S, Komatsu M : Loss of μ-crystallincauses PPARγ activation and obesity in high-fat dietfed mice. Biochemical and Biophysical ResearchCommunications 508: 914-920, 2019.
20190145
Sekido T, Nishio S, Ohkubo Y, Sekido K,
Kitahara J, Miyamoto T, Komatsu M : Repression of insulin
gene transcription by indirect genomic signaling via the
estrogen receptor in pancreatic beta cells. In Vitro Cell Dev
Biol Anim 55: 226-236, 2019.
20190146
Oiwa A, Minemura K, Nishio S, Yamazaki
M, Komatsu M : Implications of thyroid autoimmunity in
infertile women with subclinical hypothyroidism in theabsence of both goiter and anti-thyroid antibodies: lessons
from three cases. Endocr J 66: 193-198, 2019.
20190147
Sato A, Takei M, Hiramatsu K, Takeda T,
Miyamoto T, Yamazaki M, Sato Y, Komatsu M : Effects of
Sitagliptin on Pancreatic Beta-Cells in Type 2 Diabetes With
Sulfonylurea Treatment: A Prospective Randomized Study. J
Clin Med Res 11: 15-20, 2019.
20190148
Watada H, Kaneko S, Komatsu M, Agner BR,
Nishida T, Ranthe M, Nakamura J : Superior HbA1c control
with the fixed-ratio combination of insulin degludec andliraglutide (IDegLira) compared with a maximum dose of
50 units of insulin degludec in Japanese individuals with
type 2 diabetes in a phase 3, double-blind, randomized trial.

13

Diabetes Obes Metab 21: 2694-2703, 2019.

Medicine V (Cardiovascular)
20190149
Motoki H, Yasukochi S, Takigiku K, Takei K,
Okamura T, Kimura K, Minamisawa M, Okada A, Saigusa
T, Ebisawa S, Seto T, Shoda M, Okada K, Kuwahara K: Establishment of a Healthcare System for Patients with
Adult Congenital Heart Disease in Collaboration withChildren’s Hospital -The Nagano Model -. Circ J 83: 424431, 2019.
20190150
Minamisawa M, Koyama J, Ikeda U : Leftventricular noncompaction cardiomyopathy: Recent updateon genetics, usefulness of biomarkers, and speckle imaging.
J Cardiol 73: 95-96, 2019.
20190151
Kozuka A, Koyama J, Sekijima Y, Ikeda U :Quantitative Analysis of Endocardial and Epicardial Left
Ventricular Myocardial Deformation in Patients with Cardiac
Amyloidosis. Shinshu Med J 67: 49-62, 2019.
20190152
Oguchi Y, Saigusa T, Ebisawa S, Okada
A, Motoki H, Kuwahara K : Ankle-Brachial Index as a
Prognostic Indicator in Patients with Atrial Fibrillation - A
Subanalysis of the IMPACT-ABI Study. Shinshu Med J 67:
197-204, 2019.
20190153
Tabata H, Motoki H, Sakai T, Okada A,
Kuwahara K : Epicardial Stone -Unfamiliar Calcified Massat the Site of a Left Ventricular Old Myocardial Infarction -.
Circ J 83: 1969, 2019.
20190154
Nakagawa Y, Nishikimi T, Kuwahara K : Atrial
and brain natriuretic peptides: Hormones secreted from theheart. Peptides 111: 18-25, 2019.
20190155
Komatsu T, Motoki H, Kimura K, Saigusa T,
Ebisawa S, Yokokawa Y, Ando H, Ichino T, Kuwahara K: A case of thrombolytic therapy with recombinant tissue
plasminogen activator for mechanical valve thrombosis at 9
weeks of pregnancy in a Japanese woman. J Cardiol Cases
19: 15-18, 2019.

arterial tonometry index and atrial fibrillation recurrence
after catheter ablation. Int J Cardiol Heart Vasc 24: 100385,
2019.
20190158
Suzuki S, Motoki H, Minamisawa M, Okuma
Y, Shoin W, Okano T, Kimura K, Ebisawa S, Okada A,
Kuwahara K : Prognostic significance of high‑sensitivity
cardiac troponin in patients with heart failure with preserved
ejection fraction. Heart Vessels 34: 1650-1656, 2019.
20190159
Motoki H, Nishimura M, Kanai M, Kimura K,
Minamisawa M, Yamamoto S, Saigusa T, Ebisawa S, Okada
A, Kuwahara K : Impact of inpatient cardiac rehabilitation
on Barthel Index score and prognosis in patients with acutedecompensated heart failure. Int J Cardiol 293: 125-130,
2019.
20190160
An J, Naruse TK, Hinohara K, Soejima Y,
Sawabe M, Nakagawa Y, Kuwahara K, Kimura A : MRTF-A
regulates proliferation and survival properties of proatherogenic macrophages. J Mol Cell Cardiol 133: 26-35,
2019.
20190161
Ueki Y, Miura T, Mochidome T, Senda K,
Ebisawa S, Saigusa T, Motoki H, Okada A, Koyama J,
Kuwahara K : Comparison of leg loader and treadmill
exercise for evaluating patients with peripheral arterydisease. Heart Vessels 34: 590-596, 2019.
20190162
Ueki Y, Mohri M, Matoba T, Kadokami T, Suwa
S, Yagi T, Takahashi H, Tanaka N, Hokama Y, Fukuhara
R, Onitsuka K, Tachibana E, Yonemoto N, Nagao K, for
the Japanese Circulation Society Shock Registry ScientificCommittee : Prognostic Value of Neurological Status
on Hospital Arrival for Short-Term Outcome in Patients
With Cardiovascular Shock - Sub-analysis of the Japanese
Circulation Society Cardiovascular Shock Registry -. Circ J
83: 1247-1253, 2019.
20190163
Koyama J, Minamisawa M, Sekijima Y,
Kuwahara K, Katsuyama T, Maruyama K : Role ofechocardiography in assessing cardiac amyloidosis : asystematic review. J Echocardiogr 17: 64-75, 2019.

20190156
Okano T, Okada A, Tabata H, Kobayashi H,
Shoin W, Yoshie K, Oguchi Y, Shoda M, Kuwahara K :Wire perforation causing cardiopulmonary arrest during
radiofrequency hot balloon ablation for pulmonary vein
isolation. J Cardiol Cases 19: 169-172, 2019.

20190164
Itagaki T, Okada A, Tabata H, Shoin W,
Kobayashi H, Okano T, Oguchi Y, Mochidome T, Saigusa T,
Ebisawa S, Motoki H, Shoda M, Kuwahara K : Successful
inferior vena cava filter removal using pacemaker leadextraction methods. J Cardiol Cases 19: 129-132, 2019.

20190157
Kobayashi H, Okada A, Tabata H, Shoin W,
Okano T, Yoshie K, Oguchi Y, Kato K, Shoda M, Kuwahara
K : Association between reactive hyperemia peripheral

20190165
Sunohara D, Motoki H, Saigusa T, Ebisawa S,
Okada A, Ando H, Sato M, Kuwahara K : Biopsy detection
and clinical management of acute lymphocytic myocarditis

14

in pregnancy. J Cardiol Cases 20: 164-167, 2019.
20190166
Suzuki S, Motoki H, Kanzaki Y, Maruyama
T, Hashizume N, Kozuka A, Yahikozawa K, Kuwahara
K : Comparison of Long-Acting and Short-Acting Loop
Diuretics in the Treatment of Heart Failure With Preserved
Ejection Fraction. Circ Rep 1: 137-141, 2019.
20190167
Minamisawa M, Claggett B, Adams D, Kristen
AV, Merlini G, Slama MS, Dispenzieri A, Shah AM, Falk
RH, Karsten V, Sweetser MT, Chen J, Riese R, Vest J,
Solomon SD : Association of Patisiran, an RNA Interference
Therapeutic, With Regional Left Ventricular Myocardial
Strain in Hereditary Transthyretin Amyloidosis The
APOLLO Study. JAMA Cardiol 4: 466-472, 2019.
20190168
Minamisawa M, Seidelmann SB, Claggett
B, Hegde SM, Shah AM, Desai AS, Lewis EF, Shah SJ,
Sweitzer NK, Fang JC, Anand IS, O'Meara E, Rouleau JL,
Pitt B, Solomon SD : Impact of Malnutrition Using GeriatricNutritional Risk Index in Heart Failure With Preserved
Ejection Fraction. JACC Heart Fail 7: 664-675, 2019.
20190169
Ejima K, Kato K, Okada A, Wakisaka O,
Kimura R, Ishizawa M, Imai T, Toyama Y, Shoda M,
Hagiwara N : Comparison Between Contact ForceMonitoring and Unipolar Signal Modification as a Guide forCatheter Ablation of Atrial Fibrillation Prospective MultiCenter Randomized Study. Circ Arrhythm Electrophysiol 12:
e007311, 2019.

: Association of Mineralocorticoid Receptor Antagonist
Use With All-Cause Mortality and Hospital Readmissionin Older Adults With Acute Decompensated Heart Failure.
JAMA Netw Open 2: e195892, 2019.
20190173
Oshita K, Kozasa Y, Nakagawa Y, Kuwabara Y,
Kuwahara K, Nakagawa T, Nakashima N, Hiraki T, Takano
M : Overexpression of the HCN2 channel increases thearrhythmogenicity induced by hypokalemia. J Physiol Sci
69: 653-660, 2019.

Psychiatry
20190174
Asai-Takahashi Y, Sasayama D, Sugiyama
N, Maruyama F, Washizuka S. : Association of Autism
Spectrum Quotient and Profiles with Eating Behaviors
in Patients with Anorexia Nervosa and in a Non-clinicalPopulation. Shinshu Medical Journal 67: 157-166, 2019.
20190175
Gotoh L, Yamada M, Hattori K, Sasayama
D, Noda T, Yoshida S, Kunugi H, Yamada M : Levels oflysophosphatidic acid in cerebrospinal fluid and plasma of
patients with schizophrenia. Psychiatry Res 273: 331-335,
2019.
20190176
Gotoh L, Yamada M, Hattori K, Sasayama
D , N o d a T, Yo s h i d a S , K u n u g i H , Ya m a d a M . :Lysophosphatidic acid levels in cerebrospinal fluid andplasma samples in patients with major depressive disorder.
Heliyon 5(5): e01699, 2019.

20190170
Shoji K, Yanishi K, Yoshimi R, Hamada N,
Kondo K, Fujimoto K, Nakajima H, Kuwahara K, Higashi Y,
Fukumoto Y, Murohara T, Matoba S; TACT Follow up Study
Investigators : Impact of Therapeutic Angiogenesis Using
Autologous Bone Marrow-Derived Mononuclear Cells
Implantation in Critical Limb Ischemia With Scleroderma Subanalysis of the Long-Term Clinical Outcomes Survey-.
Circ J 83: 662-671, 2019.

20190177
Sasayama D, Asano S, Nogawa S, Takahashi
S, Saito K, Kunugi H. : Possible association between photicsneeze syndrome and migraine and psychological distress.
Neuropsychopharmacol Rep. 39(3): 217-222, 2019.

20190171
Yoshikawa Y, Shiomi H, Kuwahara K, Sowa
N, Yaku H, Yamashita Y, Tazaki J, Imai M, Kato T, Saito
N, Shizuta S, Ono K, Kimura T : Utility of copeptin forpredicting long-term clinical outcomes in patients with heart
failure. J Cardiol 73: 379-385, 2019.

20190179
Takaesu Y, Watanabe K, Numata S, Iwata
M, Kudo N, Oishi S, Takizawa T, Nemoto K, Yasuda Y,
Tagata H, Tsuboi T, Tsujino N, Hashimoto N, Matsui Y,
Hori H, Yamamori H, Sugiyama N, Suwa T, Kishimoto T,
Hishimoto A, Usami M, Furihata R, Iwamoto K, Fujishiro H,
Nakamura T, Mizuno K, Inagaki T, Katsumoto E, Tomita H,
Ohi K, Muraoka H, Atake K, Iida H, Nagasawa T, Fujita J,
Yamamura S, Onitsuka T, Murata A, Takayanagi Y, Noda H,
Matsumura Y, Takezawa K, Iga J, Ichihashi K, Ogasawara
K, Yamada H, Inada K, Hashimoto R: : Improvement of
psychiatrists' clinical knowledge of the treatment guidelines
for schizophrenia and major depressive disorders using theEffectiveness of Guidelines for Dissemination and Education

20190172
Yaku H, Kato T, Morimoto T, Inuzuka Y,
Tamaki Y, Ozasa N, Yamamoto E, Yoshikawa Y, Kitai T,
Taniguchi R, Iguchi M, Kato M, Takahashi M, Jinnai T,
Ikeda T, Nagao K, Kawai T, Komasa A, Nishikawa R,
Kawase Y, Morinaga T, Toyofuku M, Seko Y, Furukawa Y,
Nakagawa Y, Ando K, Kadota K, Shizuta S, Ono K, Sato Y,
Kuwahara K, Kimura T; for the KCHF Study Investigators

20190178
Sasayama D, Hattori K, Kunugi H. : Trait Loci
Mapping and CSF Proteome. Methods Mol Biol. 2044:
365-376, 2019.

15in psychiatric treatment (EGUIDE)’’ project: a nationwide
dissemination, education and evaluation study. Psychiatry
Clin Neurosci. 73: 642-648, 2019.
20190180
Tsuchimine S, Hattori K, Ota M, Hidese S,
Teraishi T, Sasayama D, Hori H, Noda T, Yoshida S, YoshidaF, Kunugi H. : Reduced plasma orexin-A levels in patientswith bipolar disorder. Neuropsychiatr Dis Treat. 15: 22212230, 2019.
20190181
Yamaguchi M, Sasayama D, Washizuka, S.
: Clinical Utility of Salivary Cytokines for Children with
Attention Deficit Hyperactivity Disorder. International
Journal of Medical, Medicine and Health Sciences. 13(8):379-382, 2019.

Pediatrics
20190182
Akagawa D, Motoki N, Hachiya A, Akazawa
Y. : Transient Q-waves in an infant with asymptomatic
myocardial infarction due to Kawasaki disease. Cardiol
Young. 29: 231-234, 2019.
20190183
Al-Kzayer LFY, Al-Aradi HMH, Shigemura
T, Sano K, Tanaka M, Hamada M, Ali KH, Aldaghir OM,
Nakazawa Y, Okuno Y. : DOCK8 mutation diagnosed using
whole-exome sequencing of the dried blood spot-derived
DNA: a case report of an Iraqi girl diagnosed in Japan. BMC
Med Genet. 20: 114, 2019.
20190184
A l - K z a y e r L F Y, Ya s s i n A K , S a l i h K H ,Shigemura T, Sano K, Al-Simaani RBY, Tanaka M,
Nakazawa Y, Okuno Y. : A Syrian Refugee in Iraq Diagnosed
as a Case of IL12RB1 Deficiency in Japan Using Dried
Blood Spots. Front Immunol. 10: 58, 2019.
20190185
Komori K, Hirabayashi K, Morita D, Hara Y,
Kurata T, Saito S, Tanaka M, Yanagisawa R, Sakashita K,
Koike K, Nakazawa Y. : Ovarian function after allogeneic
hematopoietic stem cell transplantation in children andyoung adults given 8-Gy total body irradiation-based
reduced-toxicity myeloablative conditioning. Pediatr
Transplant. 23: e13372, 2019.
20190186
Komori K, Saito S, Araya M, Morita D, Kurata
T, Hirabayashi K, Tanaka M, Koiwai K, Tauchi K, Masaki
H, Nakazawa Y. : Proton Beam Therapy for AdolescentPrimary Central Nervous System Lymphoma With Residual
Tumor After Intensive Chemotherapy: A Case Report. Pract
Radiat Oncol. 9: 333-337, 2019.
20190187
Sado T, Nakata S, Tsuno T, Sato M, Misawa
Y, Yamauchi S, Inaba Y, Kobayashi D, Wada K. :Concentrations of various forms of vitamin B(6) in ginkgo
seed poisoning. Brain Dev. 41: 292-295, 2019.
20190188
Sado T, Nakayama Y, Kato S, Homma H,
Kusakari M, Hidaka N, Gomi S, Takamizawa S, Kosho
T, Saito S, Sugano K. : Extremely young case of small
bowel intussusception due to Peutz-Jeghers syndrome with
nonsense mutation of STK11. Clin J Gastroenterol. 12: 429433, 2019.
20190189
Shigemura T, Kobayashi N, Agematsu K, Ohara
O, Nakazawa Y. : Mosaicism of an ELANE Mutation in an
Asymptomatic Mother. J Clin Immunol. 39: 106-111, 2019.
20190190
Shigemura T, Matsuda K, Kurata T, Sakashita
K, Okuno Y, Muramatsu H, Yue F, Ebihara Y, Tsuji K,
Sasaki K, Nakahata T, Nakazawa Y, Koike K. : Essential
role of PTPN11 mutation in enhanced haematopoietic
differentiation potential of induced pluripotent stem cells ofjuvenile myelomonocytic leukaemia. Br J Haematol. 187:
163-173, 2019.
20190191
Shigemura T, Yanagisawa R, Komori K,
Morita D, Kurata T, Tanaka M, Sakashita K, Nakazawa Y.
: Prevention of transfusion-transmitted cytomegalovirus
infection using leukoreduced blood components in patients
receiving seronegative umbilical cord blood transplantation.
Transfusion. 59: 3065-3070, 2019.
20190192
Takeuchi Y, Shigemura T, Kobayashi N,
Nagumo H, Furumoto M, Ogasawara K, Fujii H, Takizawa
M, Soga T, Matoba H, Masumoto J, Fukushima K, Migita
K, Ojima T, Umeda Y, Agematsu K. : Clinical features andnew diagnostic criteria for the syndrome of periodic fever,aphthous stomatitis, pharyngitis, and cervical adenitis. Int J
Rheum Dis. 22: 1489-1497, 2019.
20190193
Yanagaisawa R, Matsuda K, Ohga S, Kanegane
H, Morimoto A, Okamoto Y, Ohara A, Fukushima K,
Sotomatsu M, Nomura K, Saito AM, Horibe K, Ishii E,
Nakazawa Y. : Factors predicting the recurrence of EpsteinBarr virus-associated hemophagocytic lymphohistiocytosisin children after treatment using the HLH-2004 protocol. Int
J Hematol. 109: 612-617, 2019.
20190194
Yanagisawa R, Nakazawa Y, Matsuda K,
Yasumi T, Kanegane H, Ohga S, Morimoto A, Hashii Y,
Imaizumi M, Okamoto Y, Saito AM, Horibe K, Ishii E;
HLH/LCH committee members of the Japan Children’s
Cancer Group. : Outcomes in children with hemophagocytic
lymphohistiocytosis treated using HLH-2004 protocol inJapan. Int J Hematol. 109: 206-213, 2019.

16

20190195
Chen L, Zhai L, Al-Kzayer LFY, Sarsam
SN, Liu T, Alzakar RH, Nakazawa Y. : NeurocutaneousM e l a n o s i s i n A s s o c i a t i o n Wi t h L a rg e C o n g e n i t a lMelanocytic Nevi in Children: A Report of 2 Cases With
Clinical, Radiological, and Pathogenetic Evaluation. Front
Neurol. 10: 79, 2019.

Kojima K, Kobayashi N, Matsuzaki S, Nagasaki M, Kawai
Y, Minegishi N, Ishida N, Motoki N, Hachiya A, Nakazawa
Y, Yamamoto M, Koike K, Takeshita T. : A low-frequency
IL4R locus variant in Japanese patients with intravenous
immunoglobulin therapy-unresponsive Kawasaki disease.
Pediatr Rheumatol Online J. 17: 34, 2019.

20190196
S a i t o T, Ta n a k a M , M a t s u d a K , H o n m a
H, Komori K, Morita D, Nakazawa H, Yanagisawa R,
Nakazawa Y. : Significance of Molecular Monitoring of T
Cells for the Decision of Treatment Strategy for Epstein-Barr
Virus-associated Hemophagocytic Lymphohistiocytosis. J
Pediatr Hematol Oncol. 41: 407-409, 2019.

20190203
Okamoto Y, Kudo K, Tabuchi K, Tomizawa
D, Taga T, Goto H, Yabe H, Nakazawa Y, Koh K, Ikegame
K, Yoshida N, Uchida N, Watanabe K, Koga Y, Inoue M,
Kato K, Atsuta Y, Ishida H. : Hematopoietic stem-celltransplantation in children with refractory acute myeloid
leukemia. Bone Marrow Transplant. 54: 1489-1498, 2019.

20190197
Hagiwara S, Kudo T, Kakuta F, Inoue M,
Yokoyama K, Umetsu S, Iwama I, Yodoshi T, Tatsuki
M, Shimizu T, Nakayama Y. : Clinical safety and utilityof pediatric balloon assisted enteroscopy; A multicenterprospective study in Japan. J Pediatr Gastroenterol Nutr 68:
306-310, 2019.

20190204
Sakaguchi H, Muramatsu H, Hasegawa D,
Kudo K, Ishida H, Yoshida N, Koh K, Noguchi M, Shiba N,
Tokimasa S, Fukuda T, Goto H, Miyamura T, Nakazawa Y,
Hashii Y, Inoue M, Atsuta Y, Pediatric AML Working Groupof the Japan Society for Hematopoietic Cell Transplantation.
: Comparison of conditioning regimens for autologous stem
cell transplantation in children with acute myeloid leukemia:
A nationwide retrospective study in Japan. Pediatr Blood
Cancer. 66: e27459, 2019.

20190198
Iwama I, Shimizu H, Nambu R, OkuhiraT, Kakuta F, Tachibana N, Abe N, Honma H, Kudo T,
Nakayama Y. : Efficacy and safety of a capsule endoscopedelivery device in children. Eur J Gastroenterol Hepatol 31:
1502-1507, 2019.
20190199
Motoki N, Inaba Y, Shibazaki T, Misawa Y,
Ohira S, Kanai M, Kurita H, Nakazawa Y, Tsukahara T,
Nomiyama T, Japan Environment & Children’s Study(JECS) Group. : Maternal Exposure to Housing Renovation
During Pregnancy and Risk of Offspring with Congenital
Malformation: The Japan Environment and Children's Study.
Sci Rep. 9: 11564, 2019.
20190200
Ohira S, Motoki N, Shibazaki T, Misawa Y,
Inaba Y, Kanai M, Kurita H, Shiozawa T, Nakazawa Y,
Tsukahara T, Nomiyama T; Japan Environment & Children’s
Study (JECS) Group. : Alcohol Consumption During
Pregnancy and Risk of Placental Abnormality: The Japan
Environment and Children's Study. Sci Rep. 9: 10259, 2019.
20190201
Hyakuna N, Hashii Y, Ishida H, Umeda K,
Takahashi Y, Nagasawa M, Yabe H, Nakazawa Y, Koh
K, Goto H, Fujisaki H, Matsumoto K, Kakuda H, Yano
M, Tawa A, Tomizawa D, Taga T, Adachi S, Kato K. :Retrospective analysis of children with high-risk acute
myeloid leukemia who underwent allogeneic hematopoietic
stem cell transplantation following complete remission withinitial induction chemotherapy in the AML-05 clinical trial.
Pediatr Blood Cancer. 66: e27875, 2019.
20190202

Amano Y, Akazawa Y, Yasuda J, Yoshino K,

20190205
Yatsushiro Y, Nishikawa T, Saito A, Nakazawa
Y, Imadome KI, Nakagawa S, Kodama Y, Okamoto Y,
Kanegane H, Kawano Y. : Epstein-Barr Virus (EBV)induced B-cell Lymphoproliferative Disorder Mimicking
the Recurrence of EBV-associated Hemophagocytic
Lymphohistiocytosis. J Pediatr Hematol Oncol. 41: e44-e46,
2019.
20190206
Honma H, Nakayama Y, Kato S, Hidaka N,
Kusakari M, Sado T, Suda A, Lin Y. : Clinical features of
Helicobacter pylori antibody-positive junior high school
students in Nagano Prefecture, Japan. Helicobacter. 24:
e12559, 2019.

Dermatology
20190207
Yamamoto T, Ohtsuki M, Sano S, Morita A,
Igarashi A, Okuyama R, Kawada A. : Late-onset psoriatic
arthritis in Japanese patients. J Dermatol. 46: 169-170,
2019.
20190208
Yamamoto T, Ohtsuki M, Sano S, Morita A,
Igarashi A, Okuyama R, Kawada A : Switching biologics inthe treatment of psoriatic arthritis in Japan. J Dermatol. 46:
e113-e114, 2019.
20190209
Kiniwa Y, Yasuda J, Saito S, Saito R, Motoike
IN, Danjoh I, Kinoshita K, Fuse N, Yamamoto M, Okuyama
R. : Identification of genetic alterations in extramammary

17

Paget disease using whole exome analysis. J Dermatol Sci.
94: 229-235, 2019.
20190210
Omodaka T, Kiyohara Y, Uematsu T, Mori K,
Okuyama R. : Preoperative ultrasound evaluation of lymph
nodes for extramammary Paget's disease in the genital area. J
Dermatol. 46: 361-363, 2019.
20190211
Mikoshiba Y, Minagawa A, Koga H, Yokokawa
Y, Uhara H, Okuyama R. : Clinical and Histopathologic
Characteristics of Melanocytic Lesions on the Volar Skin
Without Typical Dermoscopic Patterns. JAMA Dermatol.
55: 578-584, 2019.
20190212
Sato Y, Shirota S, Kiniwa Y, Sekiguchi N,
Okuyama R, Koizumi T. : Thymoma-associated graft-versushost-like disease treated with high-dose i.v. immunoglobulin.
J Dermatol. 46: e224-e225, 2019.
20190213
Nihei T, Kiniwa Y, Mikoshiba Y, Joshita S,
Okuyama R. : Improvement of porphyria cutanea tarda
following treatment of hepatitis C virus by direct-acting
antivirals: A case report. J Dermatol. 46: e149-e151, 2019.
20190214
Ashida A, Sakaizawa K, Mikoshiba A, Kiniwa
Y, Okuyama R. : Circulating Tumour DNA Reflects Tumour
Burden Independently of Adverse Events Caused by
Systemic Therapies for Melanoma. Acta Derm Venereol. 99:
1184-1185, 2019.

Radiology
20190215
Ichiro Mizushima, Satomi Kasashima, Yasunari
Fujinaga, Mitsuhiro Kawano, Nobukazu lshizaka : IgG4related periaortitis/periarteritis: An under-recognizedcondition that is potentially life-threatening. Mod
Rheumatol. 29(2): 240-250, 2019.
20190216
Kentaro Miura, Kazutoshi Hamanaka,
Tomonobu Koizumi, Satoshi Kawakami, Nobutaka
Kobayashi, Ken-ichi Ito : Solid component tumor doublingtime is a prognostic factor in non-small cell lung cancer
patients. J Cardiothorac Surg. 14(1): 57-66, 2019.
20190217
Kaneko T, Mitsui T, Kaneko K, Kadoya
M, Alzheimer's Disease Neuroimaging Initiative : Newlongitudinal visual rating scale identifies structural
alterations in people with mild cognitive impairment andthose who are cognitively normal. Int J Gerontology 13:
69-75, 2019.
20190218
Kazutoshi Komori, Shoji Saito, Masayuki
Araya, Daisuke Morita, Takashi kurata, Koichi Hirabayashi,

Miyuki Tanaka, Keiichiro Koiwai, Katsunori Tauchi,
Hidekazu Masaki, Yozo Nakazawa : Proton Beam Therapy
for Adolescent Primary Central Nervous System Lymphoma
With Residual Tumor After Intensive Chemotherapy: A Case
Report. Pract Radiat Oncol. 9(5): 333-337, 2019.
20190219
Toshirou Fukushima, Takuro Noguchi, Takashi
Kobayashi, Nodoka Sekiguchi, Takesumi Ozawa, Tomonobu
Koizumi, Hisashi Tamada : Late and Rapid Relapse inMediastinum fromTesticular Germ Cell Tumor Stage I Over
13Years after Surgery. Case Rep Oncol. 12(2): 500-505,
2019.

Division of Gastroenterological, HepatoBiliary-Pancreatic, Transplantation andPediatric Surgery
20190220
Kentaro Fukushima, Takahide Yokoyama,
Shiro Miwa, Hiroaki Motoyama, Takuma Arai, Noriyuki
Kitagawa, Akira Shimizu, Tsuyoshi Notake,Akiara
Kobayashi,Shin-ichi Miyagawa : Impact of age on groin
hernia profiles observed during laparoscopic transabdominal
preperitoneal hernia repair. Surg Endosc 33(8): 2602-2611,
2019.
20190221
Okubo Y, Tokumaru S, Yamamoto Y, Miyagawa
SI, Sanjo H, Taki S. : Generation of a common innate
lymphoid cell progenitor requires interferon regulatory
factor 2. Int Immunol 31(8): 489-498, 2019.
20190222
Masahiro Kataoka, Masato Kitazawa, Shyuugo
Takahata, Nao Hondo, Shugo Takahata, Takehito Ehara,
Yuuta Yamamoto, Makoto Koyama, Nakamura Satoshi,
Motohiro Okumura, Shigeo Tokumaru, Futoshi Muranaka,
Yusuke Miyagawa, Yuuji Soejima : Laparoscopic Total
Gastrectomy for Early Gastric Cancer With a Rare Positional
Abnormality of the Common Hepatic Artery and Splenic
Vein: A Case Report. Int Surg 104(1-2): 65-68, 2019.

Division of Cardiovascular Surgery
20190223
Johannes Wedel, Maria P. Stack, TatsuichiroSeto, Matthew M. Sheehan, Evelyn A. Flynn, Isaac E.
Stillman, Sek Won Kong, Kaifeng Liu and David M. Briscoe: T Cell-Specific Adaptor Protein Regulates Mitochondrial
Function and CD4+ T Regulatory Cell Activity In Vivo
following Transplantation. J Immunol. 203(8): 2328-2338,
2019.

Division of General Thoracic Surgery
20190224
Hamanaka K, Miura K, Koyama T, Matsuoka
S, Takeda T, Yamada K, Hyogotani A : The pretreatment

18

circulating albumin-to-fibrinogen ratio in patients with nonsmall cell lung cancer: a simple, economical, and effective
biomarker. J Thorac Dis 11(suppl.3): S241-S244, 2019.
20190225
Hamanaka K, Takeda T, Ohashi M, Kumeda
H, Agatsuma H, Shimada K, Maruyama K, Yoshida K,
Nakamura T : Thoracoscopic resection of a cystic seminomaof the mediastinum. Asian J Endosc Surg 12: 354-356, 2019.
20190226
H a m a n a k a K , Ta k a y a m a H , K o y a m a T,
Matsuoka S, Takeda T, Agatsuma H, Yamada K, Hyogotani
A, Kawakami S, Ito KI : Interobserver size measurement
variability in part-solid lung adenocarcinoma using preoperative computed tomography. J Thorac Dis 11(7): 29242931, 2019.
20190227
Kosaka M, Yasuo M, Kinota F, MachidaR, Kitaguchi Y, Ushiki A, Yamamoto H, Uehara T,
Hamanaka K, Kawakami S, Hanaoka M : Probe-based
optical fiberscopy for the direct observation of peripheral
pulmonary lesions. Respir Investig 57: 481-489, 2019.
20190228
Li X, Eguchi T, Aly RG, Chintala NK, Tan KS,
Zauderer MG, Dembitzer FR, Beasley MB, Ghebrehiwet
B, Adusumilli PS, Peerschke EIB : Globular C1q receptor(gC1qR/p32/HABP1) is overexpressed in malignant pleural
mesothelioma and is associated with increased survival insurgical patients treated with chemotherapy. Front Oncol 9:1042, 2019.
20190229
Miura K, Oba T, Hamanaka K, Ito KI. : FGF2FGFR1 pathway activation together with thymidylate
synthase upregulation is induced in pemetrexed-resistantlung cancer cells. Oncotarget 10(11): 1171-1192, 2019.
20190230
Miura K, Hamanaka K, Koizumi T, Kawakami
S, Kobayashi N, Ito KI : Solid component tumor doublingtime is a prognostic factor in non-small cell lung cancer
patients. J Cardiothorac Surg 14: 57, 2019.
20190231
Matsuoka S, Koyama T, Takeda T, Yamada
K, Hyogotani A, Hamanaka K, Sekiguchi N, Koizumi
T : Development of angiosarcoma in a mediastinal non‐seminomatous germ cell tumor that exhibited growing
teratoma syndrome during chemotherapy. Thorac Cancer 10:
111-115, 2019.

Division of Breast and Endocrine Surgery
20190232
Miura K, Oba T, Hamanaka K, Ito K : FGF2FGFR1 pathway activation together with thymidylate
synthase upregulation is induced in pemetrexed-resistantlung cancer cells. Oncotarget 10: 1171-1192, 2019.

Orthopaedic Surgery
20190233
Ya m a z a k i H , H a y a s h i M , M i y a o k a S ,Hashimoto S, Kitamura Y, Isobe F, Kato H. : Venous
perfusion assist system has no additional effect compared tosimple elevation on post-operative edema in patients with
distal radial fracture treated with volar locking plate fixation:
A randomized controlled trial. J Orthop Sci 24(3): 441-446,
2019.
20190234
Okamoto M, Kito M, Yoshimura Y, Aoki
K, Suzuki S, Tanaka A, Takazawa A, Yoshida K, Ido Y,
Ishida T, Kawasaki K, Kato H : Using the Barthel Index
in assessing activities of daily living after musculoskeletal
tumour surgery: a single-centre observational study. Prog
Rehabil Med. 4: 20190010, 2019.
20190235
Yoshida K, Okamoto M, Sasaki J, Kuroda C,
Ishida H, Ueda K, Okano S, Ideta H, Kamanaka T, Sobajima
A, Takizawa T, Kito M, Aoki K, Uemura T, Haniu H, Kato
H, Saito N. : Clinical outcome of osteosarcoma and its
correlation with programmed death-ligand 1 and T cell
activation markers. Onco Targets Ther. 12: 2513-2518, 2019.
20190236
Nemoto K, Okamoto M, Kito M, Aoki K,
Suzuki S, Takazawa A, Yoshimura Y, Kato H. : Combined
treatment using Mohs' paste and neoadjuvant chemotherapy
for giant gluteal soft tissue sarcoma with malignant
fungating wound: a case report. J Surg Case Rep. 2019(5):rjz137, 2019.
20190237
Kito M, Ae K, Koyanagi H, Gokita T, Furuoka
H, Okamoto M, Tanaka A, Suzuki S, Takazawa A, Aoki
K, Yoshimura Y : Risk factor for wound complications
following wide resection of soft tissue sarcoma in the
adductor compartment of the thigh. Jpn J Clin Oncol.
49(10): 932-937, 2019.
20190238
Sobajima A, Haniu H, Nomura H, Tanaka M,
Takizawa T, Kamanaka T, Aoki K, Okamoto M, Yoshida K,
Sasaki J, Ajima K, Kuroda C, Ishida H, Okano S, Ueda K,
Kato H, Saito N : Organ accumulation and carcinogenicity
of highly dispersed multi-walled carbon nanotubes
administered intravenously in transgenic rasH2 mice. Int J
Nanomedicine. 14: 6465-6480, 2019.
20190239
Maeda K, Kobayashi Y, Koide M, Uehara S,
Okamoto M, Ishihara A, Kayama T, Saito M, Marumo K. :The Regulation of Bone Metabolism and Disorders by Wnt
Signaling. Int J Mol Sci. 20(22): 5525, 2019.
20190240

Matsuba T, Hata Y, Ishigaki N, Nakamura K,

19

Murakami N, Kobayashi H, Itsubo T, Uemura K, Kato H: Long-term clinical and imaging outcomes after primary
repair of small- to medium-sized rotator cuff tears. J Orthop
Surg (Hong Kong). 27(3): 2309499019883980, 2019.
20190241
Matsuba T, Hata Y, Ishigaki N, Nakamura K,
Kato H : Massive heterotopic ossification in the subdeltoid
space after shoulder surgery and symptomatic improvementfrom conservative treatment: a case report. Prog Rehabil
Med 4: 20190020, 2019.
20190242
Murakami K, Zhifeng H, Suzuki T, Kobayashi
Y, Nakamura Y. : The Shisa3 knockout mouse exhibits
normal bone phenotype. J Bone Miner Metab. 37(6): 967975, 2019.
20190243
Kamimura M, Ikegami S, Mukaiyama K,
Koiwai H, Nakamura Y, Taguchi A, Kato H. : Additiveeffects of eldecalcitol in poorly responding long-termbisphosphonate treatment for osteoporosis. Osteoporos
Sarcopenia. 5(2): 57-61, 2019.
20190244
Miyazawa S, Nakamura Y, Suzuki1 T, Kato
H. : Efficacy of denosumab therapy for osteoporosispseudoglioma syndrome with osteoporosis: A case report.
Mod Rheumatol Case Rep. 3: 45-48, 2019.
20190245
K o i w a i H , K a m i m u r a M , Ta k a h a s h i J ,Nakamura Y, Kato H. : Unexpected rapid increase in bonemineral density by bisphosphonate therapy after multiple
spinal fractures: a case report. J Med Case Rep. 13: 288,
2019.
20190246
Suzuki T, Nakamura Y, Kato H. : Effects ofmonthly minodronate with or without eldecalcitol addition in
osteoporosis patients with rheumatoid arthritis: An 18-monthprospective study. Osteoporos Sarcopenia. 5(4): 122-127,
2019.
20190247
Uehara M, Takahashi J, Ikegami S, Tokida R,
Nishimura H, Sakai N, Kato H. : Sagittal spinal alignment
deviation in the general elderly population: A Japanesecohort survey randomly sampled from a basic resident
registry. Spine J. 19: 349-356, 2019.
20190248
Uehara M, Takahashi J, Ikegami S, Kuraishi S,
Futatsugi T, Oba H, Takizawa T, Munakata R, Koseki M,
Kato H. : Prediction of spontaneous lumbar curve correction
after posterior spinal fusion for adolescent idiopathic
scoliosis Lenke type 1 curves. Clin Spine Surg. 32(2):E112-E116, 2019.
20190249

Uehara M, Takahashi J, Ikegami S, Oba H,

Kuraishi S, Futatsugi T, Takizawa T, Munakata R, Koseki
M, Kato H. : Determination of optimal screw number basedon correction angle for main thoracic curve in adolescentidiopathic scoliosis. J Orthop Sci 2019;24(3):415-9. 24(3):415-419, 2019.
20190250
Uehara M, Takahashi J, Ikegami S, Kuraishi
S, Futatsugi T, Oba H, Takizawa T, Munakata R, Koseki
M, Kato H. : How Much Surface Registration Accuracy is
Required Using Ct-based Navigation System in Adolescent
Idiopathic Scoliosis Surgery? Clin Spine Surg. 32(3):E166-E170, 2019.
20190251
Uehara M, Takahashi J, Kuraishi S, Ikegami S,
Futatsugi T, Oba H, Takizawa T, Munakata R, Koseki M,
Kato H. : Two-stage posterior spinal fusion for early-onset
scoliosis: Two case reports. Medicine (Baltimore). 98(9):e14728, 2019.
20190252
Uehara M, Nakamura Y, Takahashi J, Suzuki T,
Iijima M, Arakawa Y, Ida K, Kosho T, Kato H. : Efficacy ofdenosumab therapy for a 21-year-old woman with PraderWilli syndrome, osteoporosis and history of fractures: a casereport. Ther Clin Risk Manag. 15: 303-307, 2019.
20190253
Uehara M, Takahashi J, Kuraishi S, Ikegami S,
Futatsugi T, Oba H, Takizawa T, Munakata R, Kato H. :Posterior spinal fusion for scoliosis in mucopolysaccharidosis
I (Hurler syndrome). Interdiscip Neurosurg 18: 100487,
2019.
20190254
Uehara M, Takahashi J, Ikegami S, Tokida
R, Nishimura H, Kuraishi S, Sakai N, Kato H. : Impact ofdiffuse idiopathic skeletal hyperostosis on sagittal spinalalignment in the general elderly population: A Japanesecohort survey randomly sampled from a basic resident
registry. JB JS Open Access. 4(3): e0062.1-6., 2019.
20190255
Uehara M, Takahashi J, Ikegami S, Kuraishi S,
Futatsugi T, Oba H, Takizawa T, Munakata R, Koseki M,
Kato H. : Correlation of Lower Instrumented Vertebra With
Spinal Mobility and Health-related Quality of Life After
Posterior Spinal Fusion for Adolescent Idiopathic Scoliosis.
Clin Spine Surg. 32(7): E326-E329, 2019.
20190256
Uehara M, Takahashi J, Kuraishi S, Ikegami S,
Futatsugi T, Oba H, Takizawa T, Koiwai K, Otsuki T, Uehara
T, Kato H. : Effectiveness of postoperative radiation therapy
for thoracic spine hemangioma recurrence. Interdiscip
Neurosurg 18: 100560, 2019.
20190257
Kamoi F, Kondo M, Hayashi M, Uchiyama
S, Kato H. : A new technique to determine the tension in20

extensor pollicis longus reconstruction. J Hand Surg Eur
Vol. 44(8): 790-794, 2019.

Osseous Union after Posterior Lumbar Interbody Fusion.
Spine (Phila Pa 1976). 44(5): E288-E297, 2019.

20190258
Yamaguchi T, Takano K, Inaba Y, Morikawa
M, Motobayashi M, Kawamura R, Wakui K, Nishi E,
Hirabayashi SI, Fukushima Y, Kato H, Takahashi J, Kosho
T. : PIEZO2 deficiency is a recognizable arthrogryposis
syndrome: A new case and literature review. Am J Med
Genet A. 179: 948-957, 2019.

20190266
Ebata S, Oba O, Ohba T, Takahashi J, Ikegami
S, Koyama K, Kato H, Haro H. : Surgical Outcomes ofLong Fusion Using Dual Iliac Screws Bilaterally for Adult
Spinal Deformities: The Effect on the Loosening Rate andSacroiliac Joint Correction. Spine Surg Relat Res. 3(3): 236243, 2019.

20190259
Nemoto K, Sakai N, Matsuda S, Kato H. :Successful treatment of pediatric posttraumatic tibiofibularsynostosis by resection and peroneal artery perforator
adipofascial flap: A Case Report. JBJS Case Connect. 9(4):e0280, 2019.

20190267
Yahara Y, Seki S, Makino H, Watanabe K,
Uehara M, Takahashi J, Kimura T. : Three-Dimensional
Computed Tomography Analysis of Spinal Canal Length
Increase After Surgery for Adolescent Idiopathic Scoliosis:
A Multicenter Study. J Bone Joint Surg Am. 101(1): 48-55,
2019.

20190260
Tokida R, Uehara M, Ikegami S, Takahashi
J, Nishimura H, Sakai N, Kato H. : Association between
sagittal spinal alignment and physical function in theJapanese general elderly population: A Japanese cohort
survey randomly sampled from a basic resident registry. J
Bone Joint Surg Am. 101(18): 1698-1706, 2019.
20190261
Isobe F, Yamazaki H, Hayashi M, Uchiyama
S, Miyaoka S, Kato H : Prospective Evaluation of Median
Nerve Dysfunctions in Patients with a Distal Radius Fracture
Treated with Volar Locking Plating. J Hand Surg Asian Pac
Vol. 24(4): 392-399, 2019.
20190262
Mimura, T. Ikegami, S. Oba, H. Uehara, M.
Koseki, M. Takahashi, J. : Factors leading to postoperative
pain in adolescent idiopathic scoliosis patients including
sagittal alignment and lumbar disc degeneration. Eur Spine
J. 28(12): 3085-3091, 2019.
20190263
Mimura, T. Yamazaki, H. Hayashi, M. Kato, H.
: Intraosseous Epidermoid Cyst of the Radius. J Hand Surg
Am. 44(11): 996.e1-996.e5, 2019.
20190264
Kobayashi T, Karasuno H, Sano H, Hamada
J, Takase K, Tamai K, Kashiwagi K, Hayashida K, Gotoh
M, Yamamoto N, Morihara T, Hata Y, Morisawa Y :Representative survey of frozen shoulder questionnaire
responses from the Japan Shoulder Society: What are theappropriate diagnostic terms for primary idiopathic frozen
shoulder, stiff shoulder or frozen shoulder? J Orthop Sci.
24(4): 631-635, 2019.
20190265
Ushirozako H, Hasegawa T, Ebata S, Oba
H, Ohba T, Mukaiyama K, Isogai Y, Okada E, Ojima T,
Takahashi J, Haro H, Matsuyama Y. : Weekly Teriparatide
Administration and Preoperative Anterior Slippage of the
Cranial Vertebra Next to Fusion Segment < 2mm Promote

20190268
Seki S, Yahara Y, Makino H, Kobayashi K,
Nakano M, Hirano N, Watanabe K, Takahashi J, Kawaguchi
Y, Kimura T. : Differential rod contouring on thoracolumbar/
lumbar curvature in patients with adolescent idiopathic
scoliosis: An analysis with intraoperative acquisition of
three-dimensional imaging. J Orthop Sci. 24(5): 780-786,
2019.
20190269
Kurogochi D, Takahashi J, Uehara M, Ikegami
S, Kuraishi S, Futatsugi T, Oba H, Takizawa T, Munakata
R, Hatakenaka T, Koseki M, Kato H. : Ten-Year Results ofReconstruction for Rheumatoid Cervical Spine Lesions andOccurrence Factor of Subaxial Subluxation. Asian Spine J.
13(5): 730-737, 2019.
20190270
Ikegami S, Takahashi J, Uehara M, Tokida,Nishimura H, Sakai A, Kato H. : Physical performancereflects cognitive function, fall risk, and quality of life incommunity-dwelling older people. Sci Rep. 9(1): 12242,
2019.
20190271
Tensho K, Iwaasa T, Koyama S, ShimodairaH, Horiuchi H Kato H, Saito N. Fukushima N : Theinterrelationship between anterior cruciate ligament
tibial footprint and anterolateral meniscal root insertions:
Quantitative, morphological and positional analyses using
three-dimensional computed tomography images. Knee.
26(5): 969-977, 2019.
20190272
Tanaka A, Yoshimura Y, Momose T, Isobe K,
Aoki K, Kito M, Okamoto M, Suzuki S, Sano K, Kato H :Successful treatment of adult pleomorphic rhabdomyosarco
ma with bone invasion in the lower leg by chemotherapy andbiological reconstruction: A case report. J Orthop Sci. 24(5):930-935, 2019.

21

20190273
Ishida H, Haniu H, Takeuchi A, Ueda K, Sano
M, Tanaka M, Takizawa T, Sobajima A, Kamanaka T,
Saito N. : In vitro and in vivo evaluation of starfish bonederived β-tricalcium phosphate as a bone substitute material.
Materials (Basel). 12(11): 1881, 2019.

Neurosurgery

Experimental Study. Neurol Med Chir (Tokyo) 59: 79-88,
2019.
20190282
Ogiwara T, Goto T, Fujii Y, Hanaoka Y,
Hongo K, Okamoto J, Muragaki Y : Usefulness of a Newly
Developed Ultrasonic Microdissector in Neurosurgery: A
Preliminary Experimental Study. J Neurol Surg A Cent Eur
Neurosurg 80: 96-101, 2019.

20190274
Hanaoka Y, Koyama J, Ogiwara T, Miyaoka Y,
Fujii Y, Nakamura T, Horiuchi T, Hongo K : Usefulness of a
Novel Technique to Make Up for a Deficiency in Transradial
Neurointervention with a 6Fr Simmonds Guiding Sheath:
Original Experience with the Subclavian Artery Anchoring
Technique. World Neurosurg 131: e362-e370, 2019.

20190283
Ogiwara T, Miyaoka Y, Nakamura T, Tsukada
K, Yamazaki D, Ito K, Hanaoka Y, Koyama J, Horiuchi T,
Hongo K : Endoscopic Endonasal Odontoidectomy in theHybrid Operating Room. World Neurosurg 131: 137-140,
2019.

20190275
Hardian RF, Goto T, Fujii Y, Kanaya K,
Horiuchi T, Hongo K : Intraoperative facial motor evoked
potential monitoring for pontine cavernous malformation
resection. J Neurosurg 132(1): 265-271, 2019.

20190284
Ogiwara T, Nagm A, Hasegawa T, Hanaoka
Y, Ichinose S, Goto T, Hongo K: : Pitfalls of skull
base reconstruction in endoscopic endonasal approach.
Neurosurgical Rev 42(3): 683-689, 2019.

20190276
Hardian RF, Goto T, Kuwabara H, Hanaoka
Y, Kobayashi S, Kanno H, Shimojo H, Horiuchi T, Hongo
K : An autopsy case of widespread brain dissemination ofglioblastoma unnoticed by magnetic resonance imaging after
treatment with bevacizumab. Surg Neurol Int 10(137): 1-6,
2019.

20190285
Ito K, Nakamura T, Horiuchi T, Hongo K :Surgical treatment of cervical spondylosis in patients 80
years of age and older-A retrospective observational study.
PLoS ONE 14(6): 1-8, 2019.

20190277
Nagm A, Ogiwara T, Hongo K: : Letter to the
Editor. Nuances of vascularized pedicle flap for transorbitalskull base reconstruction following modified transpalpebral
transorbital approaches. J Neurosurg 130: 1781-1784, 2019.
20190278
Nagm A, Hongo K : Letter: Paratrigeminal,
Paraclival, Precavernous, or All of the Above? A
Circumferential Anatomical Study of the C3-C4 Transitional
Segment of the Internal Carotid Artery: Collecting SurgicalNuances. Oper Neurosurg 16: E108-E109, 2019.
20190279
Nagm A, Ogiwara T, Horiuchi T, Hongo K: :Letter: Comparative Analysis Between Lateral Orbital Rim
Preservation and Osteotomy for Transorbital Endoscopic
Approaches to the Cavernous Sinus: An Anatomic Study.
Oper Neurosurg 16: E37, 2019.
20190280
Nagm A, Horiuchi T, Hongo K: : Overcoming
Daunting Challenges of Clipping of Paraclinoid CarotidOphthalmic and Superior Hypophyseal Artery Aneurysms:
2-Dimensional Operative Video. Oper Neurosurg 17(6):E252-E253, 2019.
20190281
Nagm A, Ogiwara T, Hongo K: : Watertight
Robust Osteoconductive Barrier for Complex Skull Base
Reconstruction: An Expanded-endoscopic Endonasal

20190286
Ogiwara T, Nagm A, Nakamura T, Mbadugha
T, Horiuchi T, Hongo K: : Significance and indicationsof surgery for asymptomatic nonfunctioning pituitaryadenomas. World Neurosurg 128: e752-e759, 2019.

Dentistry & Oral Surgery
20190287
Hasegawa T, Hayashida S, Kondo E, Takeda
Y, Miyamoto H, Kawaoka Y, Ueda N, Iwata E, Nakahara
H, Kobayashi M, Soutome S, Yamada S, Tojyo I, Kojima Y,
Umeda M, Fujita S, Kurita H, Shibuya Y, Kirita T, Komori
T; Japanese Study Group of Co-operative Dentistry with
Medicine (JCDM). : Medication-related osteonecrosis of thejaw after tooth extraction in cancer patients: a multicenter
retrospective study. Osteoporos Int 30: 231-239, 2019.
20190288
Yamada S, Kurita H, Kondo E, Suzuki S,
Nishimaki F, Yoshimura N, Morioka M, Ishii S, Kamata T :Treatment outcomes and prognostic factors of medicationrelated osteonecrosis of the jaw: a case- and literature-based
review. Clin Oral Investig 23: 3203-3211, 2019.
20190289
Yamakawa N, Kirita T, Umeda M, Yanamoto S,
Ota Y, Otsuru M, Okura M, Kurita H, Yamada S, Hasegawa
T, Aikawa T, Komori T, Ueda M; Japan Oral Oncology
Group (JOOG) : Tumor budding and adjacent tissue at theinvasive front correlate with delayed neck metastasis inclinical early-stage tongue squamous cell carcinoma. J Surg

22

Oncol 119: 370-378, 2019.
20190290
Hasegawa T, Yanamoto S, Otsuru M, Kakei
Y, Okura M, Yamakawa N, Yamada S, Ota Y, Umeda
M, Kirita T, Kurita H, Ueda M, Komori T; Japan Oral
Oncology Group (JOOG) : Multicenter retrospective studyof the prognosis and treatment outcomes of Japaneseoral squamous cell carcinoma patients with level IV/V
metastasis. Head Neck 41: 2256-2263, 2019.
20190291
Sakurai SI, Yamada S, Karasawa I, Sakurai
A, Kurita H : A longitudinal study on the relationshipbetween dental health and metabolic syndrome in Japan. J
Periodontol. 90: 728-746, 2019.
20190292
Iwata E, Hasegawa T, Yamada S, Kawashita Y,
Yoshimatsu M, Mizutani T, Nakahara H, Mori K, Shibuya
Y, Kurita H, Komori T : Effects of perioperative oral care on
prevention of postoperative pneumonia after lung resection:
Multicenter retrospective study with propensity scorematching analysis. Surgery 165: 1003-1007, 2019.
20190293
Nishimaki F, Yamada S, Kawamoto M, Sakurai
A, Hayashi K, Kurita H : Relationship Between the Quantityof Oral Candida and Systemic Condition/Diseases of theHost: Oral Candida Increases with Advancing Age andAnemia. Mycopathologia 184: 251-260, 2019.
20190294
Aizawa H, Yamada S, Sakai H, Otagiri H,
Akita D, Gibo T, Kurita H : Nuclear protein of the testis
midline carcinoma in the oral cavity: retrospective review of
those initially diagnosed as poorly differentiated squamouscell carcinoma using an anti-C52B1 antibody. Int J Oral
Maxillofac Surg 48: 1265-1272, 2019.
20190295
Sakai H, Yamada S, Gibo T, Yoshimura N,
Nishimaki F, Kondo E, Kamata T, Kurita H : A retrospective
analysis of the prevalence of dental diseases in patients withdigestive system cancers. Medicine (Baltimore) 98: e14771,
2019.
20190296
Gibo T, Sekiguchi D, Noguchi T, Fukushima
T, Kobayashi T, Ozawa T, Yamada S, Koizumi T :Targeted therapy with trastuzumab for epidermal growth
factor receptor 2 (HER2)‑positive advanced salivary duct
carcinoma: A case report. Mol Clin Oncol 11: 111-115, 2019.
20190297
Yoshimura N, Yamada S, Aizawa H, Xiao T,
Nishimaki F, Kurita H : Glycogen metabolism in an oral
dysplastic/cancerous (iodine-negative) epithelium: glycogenwas consumed in the pentose phosphate pathway, not inglycolysis. J Oral Maxillofac Surg Med Pathol 31: 288-294,
2019.

20190298
Nagashio S, Ajima K, Maejima D, Sanjo
H, Kajihara R, Hayashi M, Watanabe-Asaka T, Kaidoh
M, Yokoyama Y, Taki S, Kawai Y, Ohhashi T : Water
intake increases mesenteric lymph flow and the total
flux of albumin, long-chain fatty acids, and IL-22 in rats:
New concept of absorption in jejunum. Am J Physiol
Gastrointestinal and Liver Physiology 316: G155-G165,
2019.
20190299
Kawashita Y, Koyama Y, Kurita H, Otsuru
M, Ota Y, Okura M, Horie A, Sekiya H, Umeda M :Effectiveness of a comprehensive oral management protocol
for the prevention of severe oral mucositis in patients
receiving radiotherapy with or without chemotherapy fororal cancer: a multicentre, phase II, randomized controlled
trial. Int. J. Oral Maxillofac. Surg 48: 857-864, 2019.
20190300
Motoki N, Inaba Y, Shibazaki T, Misawa Y,
Ohira S, Kanai M, Kurita H, Nakazawa Y, Tsukahara T,
Nomiyama T, The Japan Environment & Children’s Study(JECS) Group : Maternal Exposure to Housing Renovation
During Pregnancy and Risk of Offspring with Congenital
Malformation: The Japan Environment and Children’s Study.
Sci Rep. 9: 11564, 2019.
20190301
Li, Y, Yamada S, Aizawa H, Qi F, Shimane T,
Morioka M, Kurita H : Effect of micro-thread at implantneck on securing quantity and quality of bone formation
around implant. J Oral Maxillofac Surg Med Pathol 31:
13-19, 2019.

Urology
20190302
Minagawa T, Daimon H, Ogawa N, Saito
T, Suzuki T, Domen T, Nagai T, Ogawa T, Ishizuka O :Morphological and clinical evaluation of prostatic urethra
using modified sonourethrography with retrograde jelly
injection. LUTS 11(2): 4-10, 2019.
20190303
Minagawa T, Ogawa T, Ishizuka O : Fluid
dynamic assessment of the lower urinary tract: Exploratory
research to observe vorticity in the prostatic urethra after
transurethral enucleation. Int J Urol 26(8): 853-854, 2019.
20190304
Nagai T, Imamura T, Ogawa T, Minagawa T,
Domen T, Suzuki T, Ueno M, Ishizuka O : Nicotine-induced
hypoxia in rat urothelium deteriorates bladder storage
functions. Neurourol Urodyn 38(6): 1560-1570, 2019.
20190305
Suzuki T, Hattori R, Minagawa T, Uehara T,
Ogawa T, Ishizuka O : Intestinal injury by heat conduction
from surgical sealing devices. JSLS 23(1): e2018.00100,
2019.

23

20190306
O gaw a T, Tyagi P, Is hi z u k a O , U e d a T,
Chancellor MB, Chermansky CJ, Yoshimura N : Recent
developments in imaging in BPS/IC. Curr Bladder Dysfunct
Rep 14(4): 301-307, 2019.

Ophthalmology
20190307
Hirabayashi K, Tanaka M, Imai A, Toriyama
Y, Iesato Y, Sakurai T , Kamiyoshi, A Ichikawa-Shindo
Y, Kawate H, Tanaka M, Dai K, Cui N, Wei Y, Nakamura
K, Iida S, Matsui S, Yamauchi A, Murata T, Shindo
T : Development of a Novel Model of Central Retinal
Vascular Occlusion and the Therapeutic Potential of the
Adrenomedullin–Receptor Activity–Modifying Protein 2
System. Am J Pathol 189: 449-466, 2019.
20190308
Hoshiyama K, Nakao S, Shiose S,
Yoshikawa H, Kano K, Kaizu Y, Murata T, Sonoda K: Optical Coherence Tomography Angiography Detects
Choriocapillaris Loss in Decalcification of Choroidal
Osteoma. J Vitreoretin Dis 3: 263-268, 2019.
20190309
Fan W, Nittala MG, Velaga SB, Hirano T,
Wykoff CC, Ip M, Lampen SIR, van Hemert J, Fleming
A, Verhoek M, Sadda SR : Distribution of Nonperfusion
and Neovascularization on Ultrawide-Field Fluorescein
Angiography in Proliferative Diabetic Retinopathy(RECOVERY Study): Report 1. Am J Ophthalmol 206: 154160, 2019.

Otorhinolaryngology
20190310
Yoshimura H, Shibata SB, Ranum PT, Moteki
H, Smith RJH. : Targeted allele suppression prevents
progressive hearing loss in the mature murine model ofhuman TMC1 deafness. Mol Ther. 27: 681-690, 2019.
20190311
Yokota Y, Moteki H, Nishio SY, Yamaguchi T,
Wakui K, Kobayashi Y, Ohyama K, Miyazaki H, Matsuoka
R, Abe S, Kumakawa K, Takahashi M, Sakaguchi H, Uehara
N, Ishino T, Kosho T, Fukushima Y, Usami SI. : Frequency
and clinical features of hearing loss caused by STRC
deletions. Sci Rep 9: 4408, 2019.
20190312
Iwasa Y, Nishio SY, Sugaya A, Kataoka Y,
Kanda Y, Taniguchi M, Nagai K, Naito Y, Ikezono T, Horie
R, Sakurai Y, Matsuoka R, Takeda H, Abe S, Kihara C,
Ishino T, Morita S, Iwasaki S, Takahashi M, Ito T, Arai Y,
Usami SI. : OTOF mutation analysis with massively parallel
DNA sequencing in 2,265 Japanese sensorineural hearing
loss. PLoS One 14: e0215932, 2019.
20190313

Ideura M, Nishio SY, Moteki H, Takumi Y,

Miyagawa M, Sato T, Kobayashi Y, Ohyama K, Oda K,
Matsui T, Ito T, Suzumura H, Nagai K, Izumi S, Nisiyama
N, Komori M, Kumakawa K, Takeda H, Kishimoto Y,
Iwasaki S, Furutate S, Ishikawa K, Fujioka M, Nakanishi
H, Nakayama J, Horie R, Ohta Y, Naito Y, Kakudo M,
Sakaguchi H, Kataoka Y, Sugawara K, Hato N, Nakagawa
T, Tsuchihashi N, Kanda Y, Kihara CH, Tono T, Miyanohara
I, Ganaha A, Usami SI. : Comprehensive analysis ofsyndromic hearing loss patients in Japan. Sci Rep 9: 11976,2019.
20190314
Kitano T, Kitajiri SI, Nishio SY, Usami SI. :Detailed clinical features of deafness caused by a claudin-14
variant. Int J Mol Sci 20: 4579, 2019.
20190315
Sugiyama K, Moteki H, Kitajiri SI, Kitano T,
Nishio SY, Yamaguchi T, Wakui K, Abe S, Ozaki A, Motegi
R, Matsui H, Teraoka M, Kobayashi Y, Kosho T, Usami SI. :Mid-frequency hearing loss is characteristic clinical featureof OTOA-associated hearing loss. Genes (Basel) 10: 715,
2019.
20190316
Yasukawa R, Moteki H, Nishio SY, Ishikawa
K, Abe S, Honkura Y, Hyogo M, Mihashi R, Ikezono T,
Shintani T, Ogasawara N, Shirai K, Yoshihashi H, Ishino
T, Otsuki K, ItoT, Sugahara K, Usami SI. : The prevalence
and clinical characteristics of TECTA-associated autosomal
dominant hearing loss. Genes (Basel) 10: 744, 2019.
20190317
Maekawa K, Nishio SY, Abe S, Goto SI,
Honkura Y, Iwasaki S, Kanda Y, Kobayashi Y, Oka SI,
Okami M, Oshikawa C, Sakuma N, Sano H, Shirakura M,
Uehara N, usami SI. : Mutational spectrum and clinicalfeatures of patients with LOXHD1 variants identified in an8074 hearing loss patient cohort. Genes (Basel) 10: 735,
2019.

Obstetrics and Gynecology
20190318
Ida K, Miyamoto T, Takatsu A, Ando H, Asaka
R, Takeuchi H, Ono M, Yamada S, Asaka S, Shiozawa T. :Whole-exome sequencing of lobular endocervical glandular
hyperplasia. Oncol Lett. 18: 2592-2597, 2019.
20190319
Higuchi S, Miyamoto T, Kobara H, Yamada S,
Asaka R, Kikuchi N, Kashima H, Ohira S, Shiozawa T. :Trophoblast type-specific expression of senescence markers
in the human placenta. Placenta. 85: 56-62, 2019.
20190320
Ida K, Miyamoto T, Higuchi S, Takeuchi H,
Yamada S, Ono M, Nishihara H, Shiozawa T. : Effectivenessof a genetic test panel designed for gynecological cancer: an
exploratory study. Med Oncol. 36: 62, 2019.

24

20190321
Ida K, Yamanoi K, Asaka S, Takeuchi H,
Miyamoto T, Shiozawa T, Nakayama J. : αGlcNAc and its
catalyst α4GnT are diagnostic and prognostic markers inuterine cervical tumor, gastric type. Sci Rep. 9: 13043, 2019.
20190322
Miyamoto T, Shiozawa T. : Two-sided roleof estrogen on endometrial carcinogenesis: stimulator or
suppressor? Gynecol Endocrinol. 35: 370-375, 2019.
20190323
Asaka S, Nakajima T, Momose M, Miyamoto T,
Uehara T, Ota H. : Trefoil factor family 2 protein: a potential
immunohistochemical marker for aiding diagnosis oflobular endocervical glandular hyperplasia and gastric-typeadenocarcinoma of the uterine cervix. Virchows Arch. 474:
79-86, 2019.
20190324
Ohira S, Yamanaka S, Asaka R, Ando H,
Fuseya C, Kikuchi N, Miyamoto T, Kanai M, Shiozawa T. :Sawtooth fetal heart rate pattern associated with a favorable
neurological outcome in an infant: a case report. J Med Case
Rep. 13: 226, 2019.
20190325
Ishikawa M, Kasamatsu T, Tsuda H, Fukunaga
M, Sakamoto A, Kaku T, Kato T, Takahashi K, Ariyoshi
K, Suzuki K, Arimoto T, Matsumoto Y, Nakai H, Inoue
T, Yokoyama M, Kawabata T, Kodama S, Miyamoto T,
Takano M, Yaegashi N. : A multi-center retrospective studyof neuroendocrine tumors of the uterine cervix: Prognosis
according to the new 2018 staging system, comparing
outcomes for different chemotherapeutic regimens andhistopathological subtypes. Gynecol Oncol. 155: 444-451,
2019.
20190326
Asaka R, Le A. : Dual role of N-acetyl-aspartylglutamate metabolism in cancer monitor and therapy. Mol
Cell Oncol. 6: e1627273, 2019.
20190327
Nishio S, Mikami Y, Tokunaga H, Yaegashi N,
Satoh T, Saito M, Okamoto A, Kasamatsu T, Miyamoto T,
Shiozawa T, Yoshioka Y, Mandai M, Kojima A, Takehara K,
Kaneki E, Kobayashi H, Kaku T, Ushijima K, Kamura T. :Analysis of gastric-type mucinous carcinoma of the uterine
cervix - An aggressive tumor with a poor prognosis: A multiinstitutional study. Gynecol Oncol. 153: 13-19, 2019.
20190328
Udupa S, Nguyen S, Hoang G, Nguyen T,
Quinones A, Pham K, Asaka R, Nguyen K, Zhang C,
Elgogary A, Jung JG, Xu Q, Fu J, Thomas AG, Tsukamoto
T, Hanes J, Slusher BS, Cooper AJL, Le A. : Upregulationof the Glutaminase II Pathway Contributes to Glutamate
Production upon Glutaminase 1 Inhibition in Pancreatic
Cancer. Proteomics. 19: e1800451, 2019.

20190329
Nguyen T, Kirsch BJ, Asaka R, Nabi K,
Quinones A, Tan J, Antonio MJ, Camelo F, Li T, Nguyen
S, Hoang G, Nguyen K, Udupa S, Sazeides C, Shen YA,
Elgogary A, Reyes J, Zhao L, Kleensang A, Chaichana KL,
Hartung T, Betenbaugh MJ, Marie SK, Jung JG, Wang TL,
Gabrielson E, Le A. : Uncovering the Role of N-AcetylAspartyl-Glutamate as a Glutamate Reservoir in Cancer. Cell
Rep. 27: 491-501, 2019.
20190330
Uehara M, Nakamura Y, Takahashi J, Suzuki T,
Iijima M, Arakawa Y, Ida K, KoshoT, Kato H. : Efficacy ofdenosumab therapy for a 21-year-old woman with PraderWilli syndrome, osteoporosis and history of fractures: a casereport. Ther Clin Risk Manag. 15: 303-307, 2019.

Anesthesiology and Resuscitology
20190331
Zhang H, Kashihara T, Nakada T, Tanaka S,
Ishida K, Fuseya S, Kawagishi H, Kiyosawa K, Kawamata
M, Yamada M : Prostanoid EP4 receptor-mediatedaugmentation of Ih currents in Aβ dorsal root ganglion
neurons underlies neuropathic pain. J Pharmacol Exp Ther.
368(1): 50-58, 2019.
20190332
Hattori K, Yoshitani K, Kato S, Kawaguchi M,
Kawamata M, Kakinohana M, Yamada Y, Yamakage M,
Nishiwaki K, Izumi S, Yoshikawa Y, Mori Y, Hasegawa K,
Onishi Y : Association between motor evoked potentials
and spinal cord damage diagnosed with magnetic resonanceimaging after thoracoabdominal and descending aortic
aneurysm repair. J Cardiothorac Vasc Anesth 33(7): 18351842, 2019.
20190333
Kawamata M, Iseki M, Kawakami M, Yabuki
S, Sasaki T, Ishida M, Nishiyori A, Hida H, Kikuchi S :Efficacy and safety of controlled-release oxycodone forthe management of moderate-to severe chronic low backpain in Japan: results of an enriched enrollment randomized
withdrawal study followed by an open-label extension study.
J Pain Research 12: 363-375, 2019.
20190334
Ichino T, Tanaka S, Tanaka R, Tanaka N,
Ishida T, Sugiyama Y, Kawamata M : Transcranial motorevoked potentials of laryngeal muscles for intraoperative
neuromonitoring of the vagus nerve during thyroid surgery. J
Anesth 33(2): 221-229, 2019.
20190335
Yoshitani K, Kawaguchi M, Ishida K, Maekawa
K, Miyawaki H, Tanaka S, Uchino H, Kakinohana M, Koide
Y, Yokota M, Okamoto H, Nomura M : Guidelines for theuse of cerebral oximetry by nearinfrared spectroscopy in
cardiovascular anesthesia: a report by the cerebrospinal
Division of the Academic Committee of the Japanese25

Society of Cardiovascular Anesthesiologists (JSCVA). J
Anesth 33(2): 167-196, 2019.
20190336
Hirabayashi K, Tanaka M, Imai A, Toriyama
Y, Iesato Y, Sakurai T, Kamiyoshi A, Ichikawa-Shindo Y,
Kawate H, Tanaka M, Dai K, Cui N, Wei Y, Nakamura
K, Iida S, Matsui S, Yamauchi A, Murata T, Shindo T :Development of a novel model of central retinal vascularocclusion and therapeutic potential of the adrenomedullinreceptor activity-modifying protein 2 system. Am J Pathol
189(2): 449-466, 2019.
20190337
Matsui S, Tanaka M, Kamiyoshi A, Sakurai T,
Ichikawa-Shindo Y, Kawate H, Dai K, Cui N, Wei Y, Tanaka
M, Kakihara S, Nakamura K, Yamauchi A, Ishida K, Tanaka
S, Kawamata M, Shindo T : Endogenous Calcitonin GeneRelated Peptide Deficiency Exacerbates Postoperative
Lymphedema by Suppressing Lymphatic Capillary
Formation and M2 Macrophage Accumulation. Am J Pathol
189(12): 2487-2502, 2019.
20190338
Kawamata M, Iseki M, Kawakami M, Yabuki
S, Sasaki T, Ishida M, Nishiyori A, Hida H, Kikuchi S :Efficacy And Safety Of Controlled-Release Oxycodone For
The Management Of Moderate-To-Severe Chronic NonCancer Pain In Japanese Patients: Results From An OpenLabel Study. J Pain Research 12: 3423-3436, 2019.
20190339
Wakabayashi R, Ide S, Ishida T, Tanaka S,
Kawamata M : Severe mitral regurgitation due to geometricchanges in the mitral valve after surgical aortic valve
replacement. JA Clin Rep 5(12): 59-59, 2019.

Plastic and Reconstructive Surgery
20190340
Nakajima Y, Yuzuriha S, Nagai F, Fujita K,
Noguchi M : Oronasal transfixion suture to prevent upliftednasal floor deformity in cleft lip and palate patients: A 5-year
follow-up. Cleft Palate Craniofac J 56: 390-394, 2019.
20190341
Yasunaga Y, Yanagisawa D, Ohata E, Matsuo
K, Yuzuriha S : Bioelectrical Impedance Analysis of
Wa t e r Reduct i on i n Low er-Li m b Ly m p h e d e m a b y
Lymphaticovenular Anastomosis. J Reconstr Microsurg 5:306-314, 2019.
20190342
Nishioka H, Kondoh S, Yuzuriha S : Differencesin palpebral fissure height depending on patient’s
intraoperative head position. JPRAS Open 20: 81-89, 2019.
20190343
Yuzuriha S, Nagai F, Noguchi M : How tomanage disfiguring scars in involuted infantile hemangioma.
Adv Wound Care 8: 221-229, 2019.

20190344
Nakajima Y, Yuzuriha S, Nagai F, Fujita K,
Noguchi M : A Foxtail-shaped vermilion flap to reconstruct
the medial tubercle in asymmetric bilateral cleft lip with
contralateral lesser form defect. Cleft Palate Craniofac J 56:
1052-1057, 2019.
20190345
Yaguchi K, Noguchi M, Yasunaga Y, HoshinoY,
Yuzuriha S : Tracheoesophageal fistula due to a displaced
external tracheal stent repaired using a local flap composedof intercostal muscle and rib periosteum. J Pediatr Surg Case
Reports 42: 48-50, 2019.
20190346
Yasunaga Y, Tsuchiya A, Nakajima Y, Shoji
Kondoh, Noguchi M, Yuzuriha S : Three-dimensional
simulation for breast augmentation of female asymmetricpectus excavatum. Aesthetic Surgery J Open Forum 1: 12,2019.
20190347
I c h i n o s e Y, Ya s u n a g a Y, Yu z u r i h a S :Rheumatoid lymphedema successfully treated withlymphaticovenular anastomosis. J Reconstr Microsurg Open4: e24-e28, 2019.
20190348
Hosomi K, Iwasawa M, Kitazawa T, Nagai F :Two cases of radial ray deficiency with absence of firstmetacarpus and 2 tiny fingers. Ann Plast Surg 82: 162-165,
2019.
20190349
Suito M, Kitazawa T, Tsunekawa K, Shiba M :Intertendinous epidermoid cyst of forearm. Case Report in
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20190350
Suito M, Kitazawa T, Takashimizu I, Ikeda T :Madelung’s disease: long-team follow-up. J of Surgical Case
Reports 1: 1-4, 2019.

Laboratory Medicine
20190351
Kimura F, Kobayashi T, Kanai R, Kobayashi
Y, Yuhi O, Ota H, Yamaguchi M, Yokokawa Y, Uehara
T, Ishii K : Image quantification technology of theheterochromatin and euchromatin region for differential
diagnosis in the lobular endocervical glandular hyperplasia.
Diagn Cytopathol 47: 553-563, 2019.
20190352
Asaka S, Nakajima T, Momose M, Miyamoto
T, Uehara T, Ota H : Trefoil factor family 2 protein: a potential immunohistochemical marker for aiding diagnosis oflobular endocervical glandular hyperplasia and gastric-typeadenocarcinoma of the uterine cervix. Virchows Arch 474:
79-86, 2019.
20190353

Furukawa S, Matsuda K, Sugano M, Uehara T,26

Honda T : NLRP3 upregulation in A549 cells co-cultured
with THP-1 macrophages under hypoxia via deregulated
TGF-β signaling. Exp Cell Res 383: 111506, 2019.
20190354
Ide Y, Yanagisawa R, Kubota N, Sakashita
K, Tozuka M, Nakamura T, Honda T : Analysis of theclinical characteristics of pediatric patients who experience
ifosfamide-induced encephalopathy. Pediatr Blood Cancer
66: e27996, 2019.
20190355
Yamanaka M, Yanagisawa R, Kojima S,
Nakazawa H, Shimodaira S : Investigation of factors
associated with allergic transfusion reaction due to platelettransfusion and the efficacy of platelets resuspended in
BRS-A in adult patients. Transfusion 59: 3405-3412, 2019.
20190356
Ichimata S, Aoyagi D, Yoshinaga T, Katoh
N, Kametani F, Yazaki M, Uehara T, Shiozawa S : A caseof spheroid-type localized lactoferrin amyloidosis in the
bronchus. Pathol Int 69: 235-240, 2019.
20190357
Suzuki T, Hattori R, Minagawa T, Uehara T,
Ogawa T, Ishizuka O : Intestinal Injury by Heat Conduction
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2019.
20190358
Yamamoto H, Yasuo M, Komatsu M, Ushiki
A, Hamano H, Hori A, Nakajima T, Uehara T, Fujinaga
Y, Matsui S, Hanaoka M : Comparison of the chemokine
profiles in the bronchoalveolar lavage fluid between IgG4related respiratory disease and sarcoidosis: CC-chemokine
ligand 1 might be involved in the pathogenesis ofsarcoidosis. Cytokine 120: 125-129, 2019.
20190359
Ichimata S, Aoyagi D, Takehana T, Uehara T,
Shiozawa S : A case of large cell neuroendocrine carcinoma
exhibiting rhabdoid features in the esophagogastric junction.
Pathol Int 69: 481-487, 2019.
20190360
Kosaka M, Yasuo M, Kinota F, MachidaR, Kitaguchi Y, Ushiki A, Yamamoto H, Uehara T,
Hamanaka K, Kawakami S, Hanaoka M : Probe-based
optical fiberscopy for the direct observation of peripheral
pulmonary lesions. Respir Investig 57: 481-489, 2019.
20190361
Kuraishi Y, Uehara T, Kobayashi Y, Nakajima
T, Watanabe T, Shimizu A, Ota H, Tanaka E : Correlationof clinicopathological features and leucine-rich repeatcontaining G-protein-coupled receptor 5 expression inpancreatic ductal adenocarcinoma. Pathol Res Pract 215:
152623, 2019.
20190362

K a m i j o T, M u k a i S , Ta i r a C , H i g u c h i

Y, Okumura N : γD318Y fibrinogen shows no fibrin
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20190363
Yoshinaga T, Kurokawa T, Uehara T, Nitta J,
Horiuchi T, Sekijima Y : Optic neuropathy from connected
intra- and extraorbital lesions in IgG4-related disease.
Rinsho Shinkeigaku 59: 746-751, 2019.
20190364
Ida K, Yamanoi K, Asaka S, Takeuchi H,
Miyamoto T, Shiozawa T, Nakayama J : αGlcNAc and its
catalyst α4GnT are diagnostic and prognostic markers inuterine cervical tumor, gastric type. Sci Rep 9: 13043, 2019.
20190365
Ida K, Miyamoto T, Takatsu A, Ando H, Asaka
R, Takeuchi H, Ono M, Yamada S, Asaka S, Shiozawa T :Whole-exome sequencing of lobular endocervical glandular
hyperplasia. Oncol Lett 18: 2592-2597, 2019.
20190366
Mochizuki Y, Iwaya Y, Iwaya M, Hirota Y,
Inoue H : Pedunculated signet ring cell carcinoma of thestomach mimicking a hyperplastic polyp. Gastrointest
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20190367
Iwaya M, Ota H, Tateishi Y, Nakajima T,
Riddell R, Conner JR : Colitis-associated colorectal
adenocarcinomas are frequently associated with nonintestinal mucin profiles and loss of SATB2 expression. Mod
Pathol 32: 884-892, 2019.
20190368
Ikeda SI, Hineno A, Yoshinaga T, Matsuo K,
Suga T, Shiina T, Otsuki T, Hoshii Y : Sjögren syndromerelated plasma cell disorder and multifocal nodular AL
amyloidosis: clinical picture and pathological findings.
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20190369
Ichimata S, Kobayashi M, Ohya M, Otsuki T,
Yanagisawa K, Tateishi K, Kato A, Matsuo A, Kanno H : A
fulminant case of classical Hodgkin lymphoma: A diagnostic
dilemma of Epstein-Barr virus-positive large B-cell
neoplasms. Pathol Int 69: 407-413, 2019.
20190370
Okumura T, Takayama S, Nishio SI, Miyakoshi
T, Noguchi T, Kobayashi T, Fukushima T, Sekiguchi N,
Otsuki T, Komatsu M, Koizumi T : ACTH-producing thymic
neuroendocrine tumor initially presenting as psychosis: A
case report and literature review. Thorac Cancer 10: 16481653, 2019.
20190371
Hardian RF, Goto T, Kuwabara H, Hanaoka
Y, Kobayashi S, Kanno H, Shimojo H, Horiuchi T, Hongo
K : An autopsy case of widespread brain dissemination of

27

glioblastoma unnoticed by magnetic resonance imaging after
treatment with bevacizumab. Surg Neurol Int 10: 137, 2019.
20190372
Sunohara D, Motoki H, Saigusa T, Ebisawa S,
Okada A, Ando H, Sato M, Kuwahara K : Biopsy detection
and clinical management of acute lymphocytic myocarditis
in pregnancy. J Cardiol Cases 20: 164-167, 2019.
20190373
F u k u s h i m a T, N o g u c h i T, K o b a y a s h i T,
Sekiguchi N, Ozawa T, Koizumi T, Tamada H : Late and
Rapid Relapse in Mediastinum from Testicular Germ Cell
Tumor Stage I Over 13 Years after Surgery. Case Rep Oncol
12: 500-505, 2019.
20190374
Negishi T, Matsumoto T, Shinagawa J, Kasuga
E, Horiuchi K, Natori T, Sugano M, Uehara T, Honda T :A case of cervical subcutaneous abscess due to Bordetellahinzii. Diagn Microbiol Infect Dis 95: 114865, 2019.
20190375
Ta k e i c h i N , Ya m a z a k i H , F u j i m o t o K :Comparison of impedance measured by the forced
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2019.
20190376
Hori A, Yamaura M, Morita S, Uehara T, Honda
T, Hidaka H : Characterization of galactosyl and lactosyl
sulfatide species in human serum by MALDI-TOF mass
spectrometry. Ann Clin Biochem 56: 574-582, 2019.

Emergency and Critical Care Medicine
20190377
Imamura H : Woman with severe chest pain.
JACEP open 1(1): 53-54, 2019.
20190378
Nitta K, Okamoto K, Imamura H, Mochizuki K,
Takayama H, Kamijo H, Okada M, Takeshige K, Kashima
Y, Satou T : A comprehensive protocol for ventilator
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20190379
M i y a m a H , O k a d a M , Ta k a y a m a H ,Imamura H, Muranaka F : Cardiac Arrest Due to Tension
Pneumoperitoneum Caused by Esophagogastric Perforation
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20190380
Ueki Y, Mohri M, Matoba T, Kadokami T, Suwa
S, Yagi T, Takahashi H, Tanaka N, Hokama Y, Fukuhara R,
Onitsuka K, Tachibana E, Yonemoto N, Nagao K; Japanese
Circulation Society Shock Registry Scientific Committee. :Prognostic Value of Neurological Status on Hospital Arrival

for Short-Term Outcome in Patients With Cardiovascular
Shock - Sub-analysis of the Japanese Circulation Society
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20190381
Satou T, Imamura H, Mochiduki K, Ichikawa
M, Takeshige K, Kamijo H, Takayama H, Nitta K, Kikuchi
T, Okamoto K : Efficacy of protocol-based non-invasive
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Surg 7: e465, 2019.
20190382
Iba T, Arakawa M, Mochizuki K, Nishida
O , Wa d a H , L e v y J H : U s e f u l n e s s o f m e a s u r i n gchanges in SOFA score for the prediction of 28-day
mortality in patients with sepsis-associated disseminatedintravascular coagulation. Clin Appl Thromb Hemost 25:
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20190383
Sakamoto K, Matoba T, Mohri M, Ueki Y,
Tsujita Y, Yamasaki M, Tanaka N, Hokama Y, Fukutomi M,
Hashiba K, Fukuhara R, Suwa S, Matsuura H, Tachibana
E, Yonemoto N, Nagao K : Clinical characteristics andprognostic factors in acute coronary syndrome patientscomplicated with cardiogenic shock in Japan: analysis fromthe Japanese Circulation Society Cardiovascular ShockRegistry. Heart Vessels 34: 1241-1249, 2019.
20190384
I m a m u r a H : R e s p i r a t o r y Tr a c t B u r n s ,Traumatic Pulmonary Contusions, Crushing Death, andCrush Syndrome: What Kinds of Lung Injury Occur by
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Comprehensive Cancer Therapy
20190385
F u k u s h i m a T, N o g u c h i T, K o b a y a s h i T,
Sekiguchi N, Ozawa T, Koizumi T, Tamada H : Late andrapid relapse in mediastinum from testicular germ cell tumor
stage Ⅰ over 13 years after surgery. Case Rep Oncol 12: 500505, 2019.
20190386
Gibo T, Sekiguchi N, Gomi D, Noguchi T,
Fukushima T, Kobayashi T, Ozawa T, Yamada S, Koizumi
T : Targeted therapy with trastuzumab for epidermal growth
factor receptor 2(HER2)-positive advanced salivary duct
carcinoma: A case report. Mol Clin Oncol 11: 111-115, 2019.
20190387
Gomi D, Fukushima T, Kobayashi T, Sekiguchi
N, Koizumi T, Oguchi K : Fluorine-18-fluorodeoxyglucosepositron emission tomography evaluation in metastaticbone lesions in lung cancer: Possible prediction of pain and28skeletal-related events. Thorac Cancer 10(4): 980-987, 2019.
20190388
Kawakami T, Sekiguchi N, Kobayashi J,
Yamane T, Nishina S, Sakai H, Hirabayashi Y, Nakazawa
H, Ishida F : STAT3 mutations in natural killer cells
are associated with cytopenia in patients with chronic
lymphoproliferative disorder of natural killer cells. Int J
Hematol 109(5): 563-571, 2019.
20190389
K o m a t s u M , Ya m a m o t o H , S h o m u r a T,
Sonehara K, Ichiyama T, Urushihata K, Ushiki A, Yasuo
M, Wakamatsu T, Sugimoto S, Oto T, Date H, Koizumi T,
Hanaoka M, Kubo K : Twenty-year follow-up of the firstbilateral living-donor lobar lung transplantation in Japan.
Intern Med 58(21): 3133-3137, 2019.
20190390
Matsuoka S, Koyama T, Takeda T, Yamada
K, Hyogotani A, Hamanaka K, Sekiguchi N, Koizumi
T : Development of angiosarcoma in a mediastinal nonseminomatous germ cell tumor that exhibited growing
teratoma syndrome during chemotherapy. Thorac Cancer
10(1): 111-115, 2019.
20190391
Matsushita N, Ishida N, Ibi M, Saito M,
Takahashi M, Taniguchi S, Iwakura Y, Morino Y, TairaE, Sawa Y, Hirose M : IL-1β Plays an Important Role in
Pressure Overload-Induced Atrial Fibrillation in Mice. Biol
Pharm Bull 42(4): 543-546, 2019.
20190392
Miura K, Hamanaka K, Koizumi T, Kawakami
S, Kobayashi N, Ito KI : Solid component tumor doublingtime is a prognostic factor in non-small cell lung cancer
patients. J Cardiothorac Surg 14(1): 57, 2019.
20190393
Noguchi T, Gomi D, Fukushima T, Ozawa T,
Kobayashi T, Sekiguchi N, Mamiya K, Koizumi T : A Caceof Unresectable Pulmonary Artery Intimal Sarcoma with
Prolonged Survival by Chemotherapy. Case Rep Oncol 12:
192-198, 2019.
20190394
Okumura T, Takayama S, Nishio SI, Miyakoshi
T, Noguchi T, Kobayashi T, Fukushima T, Sekiguchi N,
Otsuki T, Komatsu M, Koizumi T : ACTH-producing thymic
neuroendocrine tumor initially presenting as psychosis: A
case report and literature review. Thorac Cancer 10(7): 16481653, 2019.
20190395
Ozawa M, Fukushima T, Noguchi T, Kobayashi
T, Sekiguchi N, Koizumi T : Intra-oesophageal invasion ofthymoma. Respirol Case Rep 7(8): e00485, 2019.
20190396
Sato Y, Shirota S, Kiniwa Y, Sekiguchi N,
Okuyama R, Koizumi T : Thymoma-associated graft-versus-

host-like disease treated with high-dose i.v. immunoglobulin.
J Dermatol 46(6): e224-e225, 2019.
20190397
S h i m o d a i r a S , Ya n a g i s a w a R , K o y a T,
Hirabayashi K, Higuchi Y, Sakamoto T, Togi M, Kato T Jr,
Kobayashi T, Koizumi T, Koido S, Sugiyama H : In vivo
administration of recombinant human granulocyte colonystimulating factor increases the immune effectiveness ofdendritic cell-based cancer vaccination. Vaccines 7: 120,2019.
20190398
S o n e h a r a K , K o b a y a s h i T, Ta t e i s h i K ,Morozumi N, Yoshiike F, Hachiya T, Ono Y, Takasuna K,
Agatsuma T, Masubuchi T, Matsuo A, Tanaka H, Morikawa
A, Hanaoka M, Koizumi T : Clinical analysis of EGFRpositive non-small cell lung cancer patients treated with
first-line afatinib: A Nagano Lung Cancer Research Group.
Thorac Cancer 10(5): 1078-1085, 2019.
20190399
Sonehara K, Tateishi K, Fukushima T, Komatsu
M, Yamamoto H, Koizumi T, Hanaoka M : The efficacy ofamrubicin third-line chemotherapy in patients with relapsed
extensive-disease small-cell lung cancer: A retrospective andhistorical study in a single institute. Thorac Cancer 10(9):1805-1811, 2019.
20190400
Sonehara K, Tateishi K, Komatsu M, Yamamoto
H, Hanaoka M, Kanda S, Koizumi T : Modified Glasgow
Prognostic Score as a Prognostic Factor in Patients with
Extensive Disease-Small-Cell Lung Cancer: A Retrospective
Study in a Single Institute. Chemotherapy 64(3): 129-137,
2019.
20190401
Watanabe Y, Nagai Y, Honda H, Okamoto
N, Yanagibashi T, Ogasawara M, Yamamoto S, Imamura
R, Takasaki I, Hara H, Sasahara M, Arita M, Hida S,
Taniguchi S, Suda T, Takatsu K : Bidirectional crosstalk
between neutrophils and adipocytes promotes adipose tissue
inflammation. FASEB J 33(11): 11821-11835, 2019.
20190402
Yamaguchi M, Okamura S, Yamaji T, Iwasaki
M, Tsugane S, Shetty V, Koizumi T : Plasma cytokine levels
and the presence of colorectal cancer. PLoS One 14(3):e0213602, 2019.
20190403
Yamaguchi M, Suzuki R, Miyazaki K, Amaki J,
Takizawa J, Sekiguchi N, Kinoshita S, Tomita N, Wada H,
Kobayashi Y, Niitsu N, Ando T, Maeda T, Saito B, Matsuoka
H, Sasaki R, Kubota N, Masaki Y, Kameoka Y, Oguchi M,
Katayama N : Improved prognosis of extranodal NK/T cell
lymphoma, nasal type of nasal origin but not extranasal
origin. Ann Hematol 98: 1647-1655, 2019.

29

Child and Adolescent Developmental
Psychiatry
20190404
Yamaguchi M, Sasayama D, Washizuka, S.
: Clinical Utility of Salivary Cytokines for Children with
Attention Deficit Hyperactivity Disorder. International
Journal of Medical, Medicine and Health Sciences 13: 379382, 2019.
20190405
Mitsuaki Iwasa, Yasuo Shimizu, Ikuko Hara,
Miho Imai, and Hideo Honda : The earlier, the better?
Diagnostic experiences of parents in a community-based
early intervention system for preschool children with autism.
Autism & Developmental Language Impairments 4: 1-12,
2019.

Infection and Host Defense

20190411
S a i t o h B Y, Ya m a s a k i R , H i w a t a s h i A ,Matsushita T, Hayashi S, Mitsunaga Y, Maeda Y, Isobe N,
Yoshida K, Ikeda SI, Kira JI, : Discriminative clinical andneuroimaging features of motor-predominant hereditarydiffuse leukoencephalopathy with axonal spheroids andprimary progressive multiple sclerosis: A preliminary crosssectional study. Mult Scler Relat Disord 31: 22-31, 2019.

Innovation of Medical and Health Sciences
Research
20190412
Nagashio S, Ajima K, Maejima D, Sanjo H,
Kajihara R, Hayashi M, Watanabe-Asaka T, Kaidoh M,
Yokoyama Y, Taki S, Kawai Y, Ohhashi T : Water intake
increases mesenteric lymph flow and the total flux ofalbumin, long-chain fatty acids, and IL-22 in rats: Newconcept of absorption in jejunum. Am J Physiol Gastrointest
Liver Physiol 316: G155-G165, 2019.

20190406
Mikawa S, Kondo M, Kaji N, Mihara T,
Yoshitake R, Nakagawa T, Takamoto M, Nishimura R,
Shimada S, Ozaki H, Hori M : Serotonin 3 receptor signaling
regulates 5-fluorouracil-mediated apoptosis indirectly via
TNF-α production by enhancing serotonin release fromenterochromaffin cells. FASEB J 33: 1669-1680, 2019.

20190413
Ohhashi T, Kawai Y : Physiology of the
Gastrointestinal Lymphatics. In: Natsugoe S ed. Lymph
Node Metastasis in Gastrointestinal Cancer. Tokyo: Springer
Nature; 2019. p.1-16.

20190407
Mitsunaga T, Norose K, Aosai F, Horie H,
Ohnuma N, Yano A. : Infection dynamics of Toxoplasma
gondii in gut-associated tissues after oral infection: The roleof Peyer's patches. Parasitol Int 68: 40-47, 2019.

20190414
Yokota Y, Moteki H, Nishio SY, Yamaguchi T,
Wakui K, Kobayashi Y, Ohyama K, Miyazaki H, Matsuoka
R, Abe S, Kumakawa K, Takahashi M, Sakaguchi H, Uehara
N, Ishino T, Kosho T, Fukushima Y, Usami SI. : Frequency
and clinical features of hearing loss caused by STRC
deletions. Sci Rep. 9: 4408, 2019.

Drug Discovery Science
20190408
Ichiyama T, Yamamoto H, Hongo K : Effectsof subtype-selective E prostanoid receptor agonists on
bleomycin-induced pulmonary fibrosis in rats. Shinshu Med
J 67: 183-195, 2019.

Brain Disease Research
20190409
Ohara S, Miyahira TA, Oguchi K, Takei
YI, Yanagimura F, Kawachi I, Oyanagi K, Kakita A, :Neuromyelitis optica spectrum disorder with massive basal
ganglia involvement: a case report. BMC Neurol. 19(1): 351,
2019.
20190410
Saito R, Nozaki H, KatoT, Toyoshima Y,
Tanaka H, Tsubata Y, Morioka T, Horikawa Y, Oyanagi K,
Morita T, onodera O, Kakita A : Retinal vasculopathy withcerebral leukodystrophy:clinicopathologic features of an
autopsied patient with a heterozygous TREX 1 mutation. J
Neuropathol Exp Neurol 78: 181-186, 2019.

Hearing Implant Sciences

20190415
Ideura M, Nishio SY, Moteki H, Takumi Y,
Miyagawa M, Sato T, Kobayashi Y, Ohyama K, Oda K,
Matsui T, Ito T, Suzumura H, Nagai K, Izumi S, Nisiyama
N, Komori M, Kumakawa K, Takeda H, Kishimoto Y,
Iwasaki S, Furutate S, Ishikawa K, Fujioka M, Nakanishi
H, Nakayama J, Horie R, Ohta Y, Naito Y, Kakudo M,
Sakaguchi H, Kataoka Y, Sugawara K, Hato N, Nakagawa
T, Tsuchihashi N, Kanda Y, Kihara CH, Tono T, Miyanohara
I, Ganaha A, Usami SI. : Comprehensive analysis ofsyndromic hearing loss patients in Japan. Sci Rep. 9: 11976,2019.
20190416
Kitano T, Kitajiri SI, Nishio SY, Usami SI.
: Detailed Clinical Features of Deafness Caused by a
Claudin-14 Variant. Int J Mol Sci. 20: 4579, 2019.
20190417
Sugiyama K, Moteki H, Kitajiri SI, Kitano T,
Nishio SY, Yamaguchi T, Wakui K, Abe S, Ozaki A, Motegi
R, Matsui H, Teraoka M, Kobayashi Y, Kosho T, Usami SI.
: Mid-Frequency Hearing Loss Is Characteristic Clinical

30

Feature of OTOA-Associated Hearing Loss. Genes. 10: 715,
2019.
20190418
Yasukawa R, Moteki H, Nishio SY, Ishikawa
K, Abe S, Honkura Y, Hyogo M, Mihashi R, Ikezono T,
Shintani T, Ogasawara N, Shirai K, Yoshihashi H, Ishino T,
Otsuki K, ItoT, Sugahara K, Usami SI. : The Prevalence andClinical Characteristics of TECTA-Associated Autosomal
Dominant Hearing Loss. Genes. 10: 744, 2019.
20190419
Maekawa K, Nishio SY, Abe S, Goto SI,
Honkura Y, Iwasaki S, Kanda Y, Kobayashi Y, Oka SI,
Okami M, Oshikawa C, Sakuma N, Sano H, Shirakura M,
Uehara N, Usami SI. : Mutational Spectrum and ClinicalFeatures of Patients with LOXHD1 Variants Identified in an8074 Hearing Loss Patient Cohort. Genes. 10: 735, 2019.

Rehabilitation Center
20190420
Oosawa R, Iwasaki R, Suzuki T, Tanabe S,
Sugawara K. : Neurophysiological Analysis of Intermanual
Transfer in Motor Learning. Front Hum Neurosci 13: 135,2019.
20190421
Yamamoto S, Yamaga T, Nishie K, Nagata C,
Mori R. : Positive airway pressure therapy for the treatmentof central sleep apnoea associated with heart failure.
Cochrane Database Syst Rev 12: CD012803, 2019.
20190422
Sakai Y, Yamamoto S, Hoshina M, Kawachi S,
Ichiyama T, Hanaoka M. : Using SpO2 Recovery Index after
a 6-Minute Walk Test to Predict Respiratory-Related Eventsin Hospitalized Patients with Interstitial Pneumonia. Sci
Rep. 9: 15226, 2019.
20190423
Tokida R, Uehara M, Ikegami S, Takahashi
J, Nishimura H, Sakai N, Kato H. : Association Between
Sagittal Spinal Alignment and Physical Function in theJapanese General Elderly Population: A Japanese Cohort
Survey Randomly Sampled from a Basic Resident Registry.
J Bone Joint Surg Am. 101: 1698-1706, 2019.
20190424
Ikegami S, Takahashi J, Uehara M, Tokida
R, Nishimura H, Sakai A, Kato H. : Physical performancereflects cognitive function, fall risk, and quality of life incommunity-dwelling older people. Sci Rep. 9: 12242, 2019.
20190425
Uehara M, Takahashi J, Ikegami S, Tokida
R, Nishimura H, Kuraishi S, Sakai N, Kato H. : Impact ofDiffuse Idiopathic Skeletal Hyperostosis on Sagittal Spinal
Alignment in the General Elderly Population: A Japanese
Cohort Survey Randomly Sampled from a Basic Resident
Registry. JB JS Open Access. : e0062, 2019.

20190426
Sato M, Ido Y, Yoshimura Y, Mutai H. :Relationship of Malnutrition During Hospitalization With
Functional Recovery and Postdischarge Destination in
Elderly Stroke Patients. J Stroke Cerebrovasc Dis. 28: 18661872, 2019.
20190427
Motoki H, Nishimura M, Kanai M, Kimura K,
Minamisawa M, Yamamoto S, Saigusa T, Ebisawa S, Okada
A, Kuwahara K. : Impact of inpatient cardiac rehabilitation
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20190428
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M, Motobayashi M, Kawamura R, Wakui K, Nishi E,
Hirabayashi S, Fukushima Y, Kato H, Takahashi J, Kosho
T. : PIEZO2 deficiency is a recognizable arthrogryposis
syndrome: a new case and literature review. Am J Med
Genet A. 179: 948-957, 2019.
20190429
Ogawa Y, Nakamura K, Ezawa N, Yamaguchi
T, Yoshinaga T, Miyazaki D, Kosho T, Sekijima T. : A novel
CACNA1A nonsense variant in a patient presenting withparoxysmal exertion-induced dyskinesia. J Neurol Sci. 399:
214-216, 2019.
20190430
Hirose T, Takahashi N, Tangkawattana P,
Minaguchi J, Mizumoto S, Yamada S, Miyake N, Hayashi
S, Hatamochi A, Nakayama J, Yamaguchi T, Hashimoto A,
Nomura Y, Takehana K, Kosho, Watanabe T. : Structural
alteration of glycosaminoglycan side chains and spatial
disorganization of collagen networks in the skin of patientswith mcEDS-CHST14. Biochim Biophys Acta Gen Subj.
1863: 623-631, 2019.
20190431
Yokota Y, Moteki H, Nishio SY, Yamaguchi T,
Wakui K, Kobayashi Y, Ohyama K, Miyazaki H, Matsuoka
R, Abe S, Kumakawa K, Takahashi M, Sakaguchi H, Uehara
N, Ishino T, Kosho T, Fukushima Y, Usami S : Frequency
and clinical features of hearing loss caused by STRC
deletions. Sci Rep. 9: 4408, 2019.
20190432
Yamasaki M, Abe K, Kosho T, Yamaguchi T.
: Familial Aortic Dissection in a Young Adult Caused by
MYH11 Gene Mutation. Ann Thorac Surg. 108: e49, 2019.
20190433
Iida A, Takano K, Takeshita E, Abe-Hatano C,
Hirabayashi S, Inaba Y, Kosugi S, Kamatani Y, Momozawa
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: Mid-Frequency Hearing Loss Is Characteristic ClinicalFeature of OTOA-Associated Hearing Loss. Genes (Basel).
10: 715, 2019.

Department of Pharmacy
20190435
Ikemura N, Yamaori S, Kobayashi C, Kamijo
S, Murayama N, Yamazaki H, Ohmori S : Inhibitory effects
of antihypertensive drugs on human cytochrome P450 2J2
activity: potent inhibition by azelnidipine and manidipine.
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20190436
Mimura A, Yamaori S, Ikemura N, Katsuyama
Y, Matsuzawa N, Ohmori S : Influence of azole antifungal
drugs on blood tacrolimus levels after switching fromintravenous tacrolimus to once-daily modified releasetacrolimus in patients receiving allogeneic hematopoietic
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Clinical Resident Training Center
20190437
K i y o t a k a H O S O D A , Yu i c h i M A S U D A ,Atsuyoshi MITA, Akira KOBAYASHI : Interferon-free
Anti-hepatitis C Virus Treatment for Long-term Liver
Transplantation Recipients with Failed Interferon Therapy.
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Medical Safety Management Room20190438
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make Asian medical students active learners? : a prospective
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20190439
Shimizu I, Mori J, Tada T : “Modified World
Café” workshop for a curriculum reform process. Asia
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Division of Animal Research
20190440
Yamanaka H, Kadomatsu R, Takagi T, Ohsawa
M, Yamamoto N, Kubo N, Takemoto T, Ohsawa K :Antimicrobial resistance profiles of vancomycin-resistantEnterococcus species isolated from laboratory mice. J Vet
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20190442
Yokoyama Y, Ono A, Yoshida M, Matsumoto
K, Saito M : Toxicological significance of increased serum
alkaline phosphatase activity in dog studies of pesticides:
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H i d e k i S a n j o , J u n N a k a y a m a , Ta k a h i r o
Yoshizawa, Hans Joerg Fehling, Shizuo Akira andShinsuke Taki : TAK1 Safeguards Macrophages against
Proinflammatory Cell Death. J Immunol 203(4): 783-788,
2019.
20190444
Tomoki Kosho, Shuji Mizumoto, Takafumi
Watanabe, Takahiro Yoshizawa, Noriko Miyake, and Shuhei
Yamada : Recent Advances in the Pathophysiology ofMusculocontractural Ehlers-Danlos Syndrome. Genes 11(1):43, 2019.

Division of Radioisotope Experiments
20190445
M Hirota, S Higaki, S Ito, Y Ishida, K Terao: Radioactive iodine volatilization inhibition efect of
cyclodextrin. J Radioanal Nucl Chem. 320: 621-625, 2019.

33

補

遺
No．47
2018

35

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Medicine II (Gastroenterology Nephrology
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Orthopaedic Surgery
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Otorhinolaryngology
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信大
州学
大医
学学
医部
学業
部績
業録
績編
録集
編要
集項
要（
項抜粋）
信州
（平成28年12月29日改正）

１．収録対象 ２．収録対象
 信州大学医学部医学科・大学院医学系研究科・医学部附属病院及び出版委員会で信州大学医学部医学科・大学院医学系研究科・医学部附属病院及び出版委員会で認めた施設等に所属する者（当該年に在籍した者全員）認めた施設等に所属する者（当該年度に在籍した者全員）
２．収録内容 ３．収録内容
収録対象は、本文が欧文で執筆された研究業績とし、次の３項目に分ける。
研究業績を次の２項目に分ける。
１）論文
１）論文
原著、綜説、展望、症例報告、速報、予報で、査読のある学術雑誌に発表のもの。
原著、綜説、展望、症例報告、速報、予報で学術雑誌に発表のもの。
学
 術集会記録（全国的又は世界的規模の集会記録で、原著論文と同様の内容をも
学術集会記録（全国的又は世界的規模の集会記録で、原著論文と同様の内容をもち、ち、別刷が発行されているもの）
別刷が発行されているもの）
２）著書
２）著書
単行書、分担執筆。
単行書、分担執筆。
３）その他
治
 療指針、トピックス、事典等、専門的知見にもとづき執筆された、論文形式の
ただし、以下のものは除外する。
記事（イ）学会発表の抄録（邦文、欧文を問わない。論文型式をとっていても学会発表に関するもの及び１頁ものの速報は抄録とみなす）
ただし、以下のものは除外する。
（ロ）セミナー、シンポジウム、その他の講演のテキストないし記録。
（イ）学会発表の抄録（邦文、欧文を問わない。論文型式をとっていても学会発表（ハ）業務報告書（文部科学省、厚生労働省、その他助成機関への研究報告書）
に関するもの及び１頁ものの速報は抄録とみなす）（ニ）座談会記事。
（ロ）セミナー、シンポジウム、その他の講演のテキストないし記録。
（ホ）学会記。
（ハ）業and
務報告書（文部科学省、厚生労働省、その他助成機関への研究報告書）（ヘ）質疑応答（ＱＡ）
、治療指針、問題集の解説、トピックス、話題、グラビア、
（ニ）
座
談会記事。
事典等に類するもの。
（ホ）学会記。
（ト）新聞記事、教育に関する記事、人物紹介、書評、随筆など学術性が認められ（ヘ）
ないもの。 論文形式をとらない質疑応答（Q and A）、問題集の解説、話題、グラビア等に類するもの。
（チ）著者表示が団体名で個人の著者性が認められないもの。
（ト）新聞・週刊誌記事、教育に関する記事、人物紹介、書評、随筆など学術性が（リ）学術雑誌とは認められないものに発表したもの。
認められないもの。
（ヌ）訳本及び訳論文。
（チ）著者表示が団体名で個人の著者性が認められないもの。
４．収録期間
毎年１月～12月

あ

と

が

き

信州大学医学部医学科・大学院医学系研究科・医学部附属病院業績録第48号をお届けします。
信州大学医学部医学科・大学院医学系研究科・医学部附属病院業績録第 38 号をお届けします。
本業績録は過去１年間、各教室や部門などでなされた４つの活動（研究活動、教育活動、診療活動、社会貢献）のうち、研究活動の成果として公表された論文を中心にまとめたものです。
本業績録は過去１年間、各講座や部門等でなされた４つの活動（研究、教育、診療、社会貢献）
自己点検、自己評価、学内・学外への報告において、本業績録の役割は重要と思われます。この１年の研究活動を振り返り、今後の方向性を考える契機にしていただければ幸いです。
のうち、研究活動の成果として公表された論文を中心にまとめたものです。自己点検、自己評
価、学内外への報告において、本業績録の果たす役割は重要と思われます。このような観点から、2019年度の信州大学医学部の英文論文は445本でした。１本１本の論文に、様々な研究者のこの１年間の研究活動を振り返り、今後の方向性等を考える契機にしていただけたら幸いに存努力、患者さんを含めた関係者の協力が込められていると思うと感慨深い数字です。ここ数年の動きとして、医学的・科学的妥当性・信頼性が保証されていないオープンアクセス誌（いわじます。
ゆるハゲタカジャーナル）が登場し、全国の大学でも問題となっております。今回出版委員会・
医学部図書館スタッフで慎重に提出論文を精査いたしまして、本業績集をまとめさせていただ
今年度の英文論文総数は昨年度より微減し、90 年度以降で最も少ない 386 という結果となりきました。
ました。しかしながら、単なる総数のみの評価が必ずしも適切であるとは言えず、今年度の業新型コロナウイルス感染（COVID-19）拡大により、2020年における大学の診療・研究・教績の中には極めて質の高い研究成果も少なくありません。今日、卒業生の大学離れや医学科入育のあり方は一変しました。希少疾患や先端的治療などの専門的診療の制限を余儀なくされて学定員数増加等により、診療や教育活動等の業務負荷は増加の一途にあります。このような現いる施設も少なくないと思われます。学術集会や班会議を通じた直接の対面交流もほとんどできなくなりました。この状況はしばらく続くと予想されます。こうした環境で、次年度以降の状ではありますが、研究活動は大学が大学であるための大きな責務であり、外部評価基準の重信州大学医学部の業績はどのようになっていくでしょうか。希望的には、オンラインでの診療要項目であることは言うまでもありません。今後、各講座・部門等でのさらなる研究の発展をおよび学術交流が国内国外を問わず一気に加速したこと、また、地方大学ならではの苦労の種
祈念致します。
であった多くの出張がなくなり自身の研究に向き合える時間が増えたことは、もしかしたら、高品質の研究をじっくり進められるという「追い風」にもなり得るのではないかと考えています。１本の論文が研究者の人生を変えることもあります。今後どのような環境にあったとして最後に、本業績録の編集にあたりご尽力頂きました先生方、図書館職員の方々に厚く御礼申も、信州大学医学部から個性豊かな研究成果が論文として発信されること、そして、「見守り役」
し上げます。
としてこの業績集がさらに発展することを祈念いたします。
最後に、本業績録の編集にあたりご尽力頂きました先生方、図書館職員の方々に厚く御礼申
浅村英樹
し上げます。
 出 版 委 員 長：浅村英樹
古庄知己
出 版 委 員：奥山隆平、石田文宏、川股知之
出 版 委 員 長：古庄知己
医学部図書館主査：石坂憲司
出 版 委 員：清水公裕、小山淳一、前野一真
医 学 部 図 書 館：後閑壮登

信州大学医学部医学科・大学院医学系研究科
・医学部附属病院業績録 第
第 48
38 号
号
平成
年１月
日印刷
令和 23
3年
6 月 728日印刷
平成年１月
28 日発行令和 23
3年
6 月10日発行
編集兼 信 州 大 学 医 学 部
発行者 松本市旭 3 丁目 1 の 1
印刷所

藤原印刷株式会社

松本市新橋 7 の 21 番地

ISSN 1881ー4980

信 州 大 学 医 学 部 医 学 科・大 学 院 医 学 系 研 究 科・医 学 部 附 属 病 院 業 績 録

SCIENTIFIC ACHIEVEMENTS OF SHINSHU UNIVERSITY SCHOOL OF
MEDICINE, SHINSHU UNIVERSITY GRADUATE SCHOOL OF MEDICINE,
AND SHINSHU UNIVERSITY HOSPITAL
信州大学医学部医学科・大学院医学系研究科・医学部附属病院業績録

No.48 (2019)

第四八号（二〇一九）
二〇二〇2020