Production-scale freeze granulator (Dry cooling method)
Cryochamber ‒ CS30
The chamber has a three-layer structure consisting of a liquid nitrogen-ﬁlled layer and a vacuum insulation layer. Thebarrel freeze-drying unit (TFD-10) can be replaced during operation thanks to the use of vaporized nitrogen gas insteadof liquid nitrogen. It also saves energy consumption compared to using liquid nitrogen directly.
Liquid material

Compressed gas

Liquid nitrogen

Liquid nitrogen feeding layer

Cryochamber(‒10〜‒120℃)

Evaporated nitrogen gas

Vacuum insulation layer

Exhaust gas

Atomization

Easy container replacement

Freeze Granulator
Feed capacity (kg/h)

Up to 15

Atomization mode

Two-ﬂuid nozzle

Cryochamber diameter (mm)

Φ300

Cooling temperature (°C)

-10 up to -120

Cooling method

Dry cooling with liquid nitrogen

Major material

Stainless steel

Barrel freeze-drying unit ‒ TFD-10
By connecting to the Cryochamber (CS30), frozen granules can be collected continuously. The process achieves zerocontamination by seamlessly connecting the granulation and drying processes. The swinging movement of the barrel
allows the ﬂowing granules to be evenly mixed and promotes drying eﬃciency.

Freeze Granulator

www.preci.co.jp

Contact for inquiries
Contact for inquiries

PRECI Co., Ltd.
Kawasaki office and Powder Technical Center
4-16-20 Kokan-dori, Kawasaki-ku, Kawasaki-shi, Kanagawa 210-0852 Japan
T +81-44-328-7665

Headquarters and Tokyo office

Precision Cleaning Test Center

2-11-6 Taito, Taito-ku, Tokyo 110-0016 Japan
T +81-3-3839-4540

1-1-23 Ryoke, Kawaguchi-shi, Saitama 332-0004 Japan

Full capacity (L)85Trapping capacity (kg)

10Kawaguchi office and Biotechnical CenterTrapping temperature (°C)-40

3-16-11 Iizuka, Kawaguchi-shi, Saitama 332-0023 JapanT +81-48-258-5335

Major material

Stainless steel
Information in this brochure is current as at the time of printing. ©2021 PRECI Co., Ltd. All rights reserved.

Freeze granulation

Characteristic

Freeze granulation is an industrial process of producing spherical granules with excellent ﬂuidity by spraying a liquid■ Particle size range is about 10-700µm■ Less oxidizable than high temperature drying process■ Fine ceramics and metal composites■ Carrier particles in catalysts■ Spherical granules with excellent ﬂuidity■ Density control is possible by adjusting the solid■ MIM and Extruded powder ﬁlling■ LED material■ Material synthesis■ Thermal spray material■ Redispersion processing of nano powder and CNT■ Pharmaceuticals and biomaterials

material under ultra-low temperature environment. The sprayed raw material instantaneously gets frozen and driedgranules are obtained after sublimation (freeze drying) process. Granules produced by freeze granulation are sphericaland have excellent ﬂuidity and can maintain high homogeneity.

concentration■ Less deformation of granules■ Less material loss and high yield■ No transfer of ﬁne particles and binder

Wet cooling method
Liquid material

Applicable ﬁelds■ Low density and soft granules

Dry cooling method

Compressed gas

Liquid material■ Low possibility of contamination

Compressed gas■ Possible to process from small volume (50-100ml)■ Uniformly dispersed granules without becoming hollow

to large volume

Liquid nitrogen■ Easy cleaning

Atomization

Atomization

Liquid nitrogen feeding layer

Evaporated nitrogen gas

Vacuum insulation layer

Cryochamber(-10~120℃)

LS-6 Series (PowderPro)

Reference
Al203 66wt% Slurry

Lab-scale freeze granulator (Wet cooling method)

Process type：CS30

Dv50：140µm

Liquid nitrogen(-196℃)

Frozen granules

Sublimation (freeze drying)

SUS316 88wt% Slurry

Freeze granulator VS Spray dryer

Process type：LS-6nms

Dv50：150µm

Feed capacity (kg/h)

Up to 6

Atomization mode

Two-ﬂuid nozzle

Cryochamber diameter (mm)Φ120

Cooling temperature (°C)-196°
CCooling method

Wet cooling with liquid nitrogen

Small batch type freeze dryer - FDU-2110

Granules produced by freeze granulation process neither shrink nor transfer ﬁne particles compared to the spray drying
method, so granules are hardly hollow in shape, and high-dispersion, low-density and homogeneous spherical granules
can be obtained. The particle size distribution (PSD) of the granules is wider (10-700µm) than spray drying, and tap density equal to or higher than spray drying can be obtained. Also, unlike high temperature hot air drying processes, it is possible to minimize the oxidation of the raw material during the production process.

Freeze granulation

Cellulose nanoﬁber 2wt% Slurry

Spray drying

Process type：LS-6

Dv50：400µm

Shrinkage during drying process increases granule density
No shrinkage maintains density and homogeneity
・Transfer of binder and ﬁne particles
・Build a hard shell
・Become hollow

Sublimation

Evaporation

Capacity

300g × 6 trays

Trapping capacity (L)3Trapping temperature (°C)-80