内科学講座糖尿病・ 代謝・内分泌内科分野
氏名

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専門分野

主な論文・著作・業績①Maegawa H, Ishigaki Y, Langer J, Saotome-Nakamura A, Andersen M; Japan Diabetes Clinical Data Management(JDDM) Study Group. Clinical inertia in patients with type 2 diabetes treated with oral antidiabetic drugs: resultsfrom a Japanese cohort study (JDDM53). J Diabetes Investig. 2020 Jul 8. doi: 10.1111/jdi.13352. Online ahead ofprin②Takeuchi T, Ishigaki Y, Hirota Y, Hasegawa Y, Yorifuji T, Kadowaki H, Akamizu T, Ogawa W, Katagiri H. Clinicalcharacteristics of insulin resistance syndromes: A nationwide survey in Japan. J Diabetes Investig. 2020

石垣泰

内科学講座糖尿病・代謝・内分泌内科分野

May;11(3):603-616.
教授

医学博士

代謝学

③Todate Y, Uwano I, Yashiro S, Chida A, Hasegawa Y, Oda T, Nagasawa K, Honma H, Sasaki M, Ishigaki Y. HighPrevalence of Cerebral Small Vessel Disease on 7T Magnetic Resonance Imaging in Familial
Hypercholesterolemia. J Atheroscler Thromb. 2019;26(12):1045-1053.
④Ishigaki Y, Kawagishi N, Hasegawa Y, Sawada S, Katagiri H, Satomi S, Oikawa S. Liver Transplantation for
Homozygous Familial Hypercholesterolemia. J Atheroscler Thromb. 2019; 26(2):121-127.
⑤日本学術振興会科学研究費・基盤研究(C) 「課題名：高度肥満者の内臓脂肪組織における調節機構破綻のメカニズ
ムの解明（代表）」2018年①Oba S, Noda M, Waki K, Nanri A, Kato M, Takahashi Y, Poudel-Tandukar K, Matsushita Y, Inoue M, Mizoue T,
Tsugane S; for the Japan Public Health Center-based Prospective Study Group.

Smoking Cessation Increases

Short-Term Risk of Type 2 Diabetes Irrespective of Weight Gain: The Japan Public Health Center-Based
Prospective Study.

PLoS One. 2012;7(2):e17061. Epub 2012 Feb 13.

②Tsujimoto T, Kajio H, Takahashi Y, Kishimoto M, Noto H, Yamamoto-Honda R, Kamimura M, Morooka M, Kubota
K, Shimbo T, Hiroe M, Noda M. Asymptomatic coronary heart disease in patients with type 2 diabetes with
vascular complications: a cross-sectional study. BMJ Open. 2011; 2:e000139.
高橋義彦

内科学講座糖尿病・代謝・内分泌内科分野③Isogawa A, Noda M, Takahashi Y, Kadowaki T, Tsugane S. Coffee consumption and risk of type 2 diabetes.
准教授

医学博士

代謝学・内分泌学

Lancet 2003; 361:702-703.
④Takahashi Y, Noda M, Tsugane S, Kuzuya T, Ito C, Kadowaki T. Prevalence of diabetes estimated by plasma
glucose criteria combined with standardized measurement of HbA1c among health checkup participants on
Miyako Island, Japan. Diabetes Care 2000; 8: 1092-1096.
⑤Takahashi Y, Kadowaki H, Ando A, Quin JD, MacCuish AC, Yazaki Y, Akanuma Y, Kadowaki T. Two aberrant
splicings caused by mutations in the insulin receptor gene in cultured lymphocytes from a patient with RabsonMendenhall's syndrome. J.Clin.Invest. 1998; 101: 588-594.

内科学講座糖尿病・ 代謝・内分泌内科分野
氏名所属

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専門分野

主な論文・著作・業績① Fujita N, Baba T, Tomiyama T, Kodama T, Kato N. Hyperinsulinaemia and blood pressure withinsulinom. BMJ. 304(6835):1157(1992)② 武部典子、藤丸潔、松原潔、種市春仁、歳弘真貴子、吉成仁、石田弥、金子能人、澤田哲伸、佐々木正孝、佐藤俊一．悪性貧血を合併した抗グルタミン酸脱炭酸酵素抗体陽性の緩徐進行型1型糖尿病の一例．糖尿病．43：367-371(2000)③ Murai T, Takebe N, Nagasawa K, Todate Y, Nakagawa R, Nakano R, Hangai M, Hasegawa Y, Takahashi Y,
Yoshioka K, Ishigaki Y. Association of epicardial adipose tissue with serum level of cystatin C in type 2 diabetes.
武部典子

内科学講座糖尿病・代謝・内分泌内科分野

PLoS One. 2017; 12(9):e0184723.
講師

医学博士

代謝学・内分泌学④ Nakano R, Takebe N, Ono M, Nakagawa R, Yashiro S, Murai T, Nagasawa K, Takahashi Y, Satoh J, and Ishigaki Y.
Involvement of oxidative stress in atherosclerosis development in subjects with sarcopenic obesity. Obes Sci
Pract. 2017; 3(2):212-218⑤ Hangai M, Takebe N, Honma H, Sasaki A, Chida A, Nakano R, Togashi H, Nakagawa R, Oda T, Matsui M, YashiroS, Nagasawa K, Kajiwara T, Takahashi K, Takahashi Y, Satoh J, and Ishigaki Y. Association of Advanced Glycation
End Products with coronary Artery Calcification in Japanese Subjects with Type 2 Diabetes as Assessed by Skin
Autofluorescence. J Atheroscler Thromb. 2016; 23(10):1178-1187.

① Nakamura M, Tanaka F, Segawa T, Takahashi T, Matsuura Y, Sakai T, Nishiyama O, Niiyama M, Onoda T,Koshiyama M, (on behalf of Northern Iwate Heart Disease Registry Consortium) . Temporal Trends in theIncidence and Clinical Features of Acute Myocardial Infarction in a Japanese Rural Area From 2006 to 2014. Circ J2017; 81: 1854–1861.
② Koeda Y, Tanaka F, Segawa T, Ohta M, Ohsawa M, Tanno K, Makita S, Ishibashi Y, Itai K, Omama S, Onoda T,Sakata K, Ogasawara K, Okayama A, Nakamura M. Comparison between urine albumin-to-creatinine ratio andurine protein dipstick testing for prevalence and ability to predict the risk for chronic kidney disease in the general
瀬川利恵

内科学講座糖尿病・代謝・内分泌内科分野

population (Iwate-KENCO study): a prospective community-based cohort study.BMC Nephrol. 2015;12;17(1):46.
講師

医学博士

代謝学・内分泌学③ Koeda Y, Tanaka F, Segawa T, Ohta M, Ohsawa M, Tanno K, Makita S, Ishibashi Y, Omama S, Onoda T,Nakamura M.Usefulnes of risk grading system using albuminuria for predicting cardiovascular events and allcause death in chronic kidney disease: a population-based prospective cohort study in Japan. Int J Cardiol.2014;175(3):576-577.
④ 瀬川利恵,中村元行. BNPとNT-proBNP, どちらが優れている? そのメリットとデメリット. Mebio .2013;30(1): 109114.
⑤ Toshie S, Motoyuki N, Kazuyoshi I, Toshiyuki O, Akira O, Katsuhiko H. B-type Natriuretic Peptide Levels andRisk Factors for Congestive Heart Failure in a Japanese General Population. Int Heart J. 2005;46(3):465-75.

内科学講座糖尿病・ 代謝・内分泌内科分野
氏名所属

職名取得学位

専門分野

主な論文・著作・業績①Todate Y, Uwano I, Yashiro S, Chida A, Hasegawa Y, Oda T, Nagasawa K, Honma H, Sasaki M, Ishigaki Y.High
Prevalence of Cerebral Small Vessel Disease on 7T Magnetic Resonance Imaging in Familial
Hypercholesterolemia. J Atheroscler Thromb. 2019 Mar 15. doi: 10.5551/jat.48553.
②Ishigaki Y, Kawagishi N, Hasegawa Y, Sawada S, Katagiri H, Satomi S, Oikawa S.Liver Transplantation for
Homozygous Familial Hypercholesterolemia.J Atheroscler Thromb. 2019 Feb 1;26(2):121-127③Yashiro S, Kameda H, Chida A, Todate Y, Hasegawa Y, Nagasawa K, Uwano I, Sasaki M, Ogasawara K, Ishigaki
Y.Evaluation of Lenticulostriate Arteries Changes by 7 T Magnetic Resonance Angiography in Type 2 Diabetes.J

長谷川豊

内科学講座糖尿病・代謝・内分泌内科分野

特任講師

医学博士

代謝学（糖尿病）

Atheroscler Thromb. 2018 Oct 1;25(10):1067-1075④Hasegawa Y, Ikeda K, Chen Y, Alba DL, Stifler D, Shinoda K, Hosono T, Maretich P, Yang Y, Ishigaki Y, Chi J,Cohen P, Koliwad SK, Kajimura S.Repression of Adipose Tissue Fibrosis through a PRDM16-GTF2IRD1 Complex
Improves Systemic Glucose Homeostasis.Cell Metabolism. 2018 Jan 9;27(1):180-194⑤Altshuler-Keylin S, Shinoda K, Hasegawa Y, Ikeda K, Hong H, Kang Q, Yang Y, Perera RM, Debnath J, Kajimura S.
Beige Adipocyte Maintenance Is Regulated by Autophagy-Induced Mitochondrial Clearance.Cell Metab. 2016 Aug24. pii: S1550-4131(16)30378-3.

①Ohara M, Maesawa C, Takebe N, Takahashi T, Yamashina M, Ono M, Matsui M, Sasai T, Honma H, Nagasawa K,Fujiwara F, Kajiwara T, Taneichi H, Takahashi K, Satoh J: Different susceptibility to insulin resistance and fatty
liver depending on the combination of TNF-α C-857T and adiponectin G+276T gene polymorphisms in Japanese
本間博之

内科学講座糖尿病・代謝・内分泌内科分野

助教

代謝学（糖尿病）

subjects with type 2 diabetes. Tohoku J Exp Med. 226(2):161-169, 2012.73.
②藤田友嗣、本間博之、佐藤譲、藤野靖久、小野寺誠、井上義博、遠藤重厚：中国製健康食品中のグリメピリドおよびロシグリタゾンの検出事例、中毒研究

24（1）：51-56、2011.

Nagasawa K, Kaneko Y, Taneichi H, Ishii M, Masaya M, Honma H, Kakino S, Takahashi K, Yoshioka Y, Satoh J:
長澤幹内科学講座糖尿病・代謝・内分泌内科分野

Association of decrease in liver triglyceride content with increase in plasma adiponectin levels after pioglitazone
助教

医学博士

代謝学（糖尿病）

treatment in Japanese patients with type 2 diabetes. J Iwate Med Assoc 62(1): 59-66, 2010.

Oda T, Taneichi H, Takahashi K, Togashi H, Hangai M, Nakagawa R, Ono M, Matsui M, Sasai T, Nagasawa K,
小田知靖

内科学講座糖尿病・代謝・内分泌内科分野

Honma H, Kajiwara T, Takahashi Y, Takebe N, Ishigaki Y, Satoh J：Positive association of free triiodothyronine with助教

医学博士

代謝学（糖尿病）

pancreatic β-cell function in people with prediabetes：Diabet Med. 2014 Sep 26.

内科学講座糖尿病・ 代謝・内分泌内科分野
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主な論文・著作・業績
Mari Hangai, Noriko Takebe, Hiroyuki Honma, Atsumi Sasaki,Ai Morita, Rieko Nakano, Hirobumi Togashi, Riyuki
Nakagawa,Tomoyasu Oda, Mizue Matsui, Takayoshi Sasai, KanNagasawa, Takashi Kajiwara, Kazuma

半谷真理

内科学講座糖尿病・代謝・内分泌内科分野

Takahashi,Yoshihiko Takahashi, Jo Satoh, Yasushi Ishigak:Association of Advanced Glycation End Products with
代謝学（糖尿病）

助教（任期付）coronaryArtery

Calcification

inJapanese

Subjectswith

Type

2Diabetes

as

AssessedbySkin

Autofluorescence,Journal of atherosclerosis and thrombosis, 23(10), 1178-1187, 2016 Oct 1

佐々木敦美

内科学講座糖尿病・代謝・内分泌内科分野

代謝学（糖尿病）

助教（任期付）

Yusuke Todate, Ikuko Uwano, Satoshi Yashiro, Ai Chida, Yutaka Hasegawa, Tomoyasu Oda, Kan Nagasawa,外舘佐藤祐介

まりの内科学講座糖尿病・代謝・内分泌内科分野

内科学講座糖尿病・代謝・内分泌内科分野

Hiroyuki Honma, Makoto Sasaki, Yasushi Ishigaki:High Prevalence of Cerebral Small Vessel Disease on 7T
助教（任期付）

医学博士

代謝学（糖尿病）

Magnetic Resonance Imaging in Familial Hypercholesterolemia:J Atheroscler Thromb. 2019 Dec 1;26(12):10451053.

助教（任期付）代謝学（糖尿病）