微生物学講座分子微生物学分野
氏名

所属

職名

取得学位

専門分野

主な論文・著作・業績① Kodama,Y.,Shimoyama,Y., Ishikawa,T., Kimura, S.,Sasaki,M: Characterization and pathogenicity offibronectin binding protein FbpI of Streptococcus intermedius. Arch Microbiol, doi: 10.1007/s00203-02001922-y.(2020)② Sasaki,M.,Shimoyama,Y.,Ishikawa,T.,Kodama,T.,Tajika,S., Kimura, S. Contribution of diﬀerent adherent

properties of Granulicatella adiacens and Abiotrophia defectiva to their associations with oral colonizationand the risk of infective endocarditis. J Oral Sci, 62: 36-39, (2020).
佐々木実

微生物学講座分子微生物学分野

病態系口腔科学 ③ Sasaki,M., Kodama,Y.,Shimoyama,Y., Ishikawa,T., Kimura, S.. Aciduricity and acid tolerance mechanisms of教授

博士（薬学） 関連、微生物学、免疫学

Streptococcus anginosus. J Gen. Appl. Microbiol., 64: 174-179, (2018)④ Kodama,Y.,Ishikawa,T., Shimoyama,Y.Sasaki,D., Kimura,S.,Sasaki, M. The ﬁbronectin-binding protein

homologue Fbp62 of Streptococcus anginosus is a potent virulence factor. Microbiology and Immunology, 62:
624-634, (2018)⑤ Sasaki, M., Yamaura, C., Ohara-Nemoto, Y., Tajika, S., Kodama, Y., Ohya, T., Harada, R. and Kimura, S.:

Streptococcus anginosus infection in oral cancer and its infection route. Oral Dis., 11: 151-156 (2005)①Shimoyama, Y., Ohara-Nemoto, Y., Kimura, M., Nemoto T. K., Tanaka, M. and Kimura, S.: Dominantprevalence of Porphyromonas gingivalis fimA types I and IV in healthy Japanese children. J. Dent. Sci., 12: 213219 (2017).
②Shimoyama, Y., Sasaki, M., Ohara-Nemoto, Y., Nemoto, T. K., Ishikawa, T. and Kimura, S.: Rapid
identification of Abiotrophia/Granulicatella species by 16S rRNA-based PCR and RFLP. In Interface Oral
Health Science 2011 (Sasaki, K. et al., eds.), Springer Japan, Tokyo, 206-208 (2012).

下山佑

微生物学講座分子微生物学分野

病態系口腔科学講師

博士（⻭学） 関連、微生物学、免疫学③Ohara-Nemoto, Y., Nakasato, M., Shimoyama, Y., Baba, T. T., Kobayakawa, T., Ono, T., Yaegashi, T., Kimura,S. and Nemoto, T. K.: Degradation of Incretins and Modulation of Blood Glucose Levels By Periodontopathic
Bacterial Dipeptidyl Peptidase 4. Infect. Immun., 85: e00277-17 (2017).
④Ohara-Nemoto, Y., Shimoyama, Y., Kimura, S., Kon, A., Haraga, H., Ono, T. and Nemoto, T. K.: Asp- and Gluspecific novel dipeptidyl peptidase 11 of Porphyromonas gingivalis that ensures utilization of proteineousenergy sources.
J. Biol. Chem., 286: 38115-38127 (2011)⑤文部科学省科学研究費補助⾦ 基盤研究(Ｃ)「課題名：⻭⾁縁下プラークでの細菌共生関係解明に向けた⻭周病
原性細菌生育機構の解析」（平成30年度〜平成32年度）研究代表者

微生物学講座分子微生物学分野
氏名

所属

職名

取得学位

専門分野

主な論文・著作・業績①Ishikawa T, Terashima J, Sasaki D, Shimoyama Y, Yaegashi T and Sasaki M: Establishment and use of athree-dimensional ameloblastoma culture model to study the effects of butyric acid on the transcription ofgrowth factors and laminin β3. Archives of Oral Biology, 21;118:104845 (2020)②Ishikawa T, Terashima J, Shimoyama Y, Ohashi Y, Mikami T, Takeda Y and Sasaki M: Eﬀects of butyric acid,a bacterial metabolite, on the migration of ameloblastoma mediated by laminin 332. Journal of oral science
2020年2月accepted石河太知

微生物学講座分子微生物学分野

病態系口腔科学
助教

博士（⻭学） 関連、微生物学、免疫学③Ishikawa T, Wondimu Z, Oikawa Y, Gentilcore G, Kiessling R, Egyhazi Brage S, Hansson J and Patarroyo M:Laminins 411 and 421 differentially promote tumor cell migration via α6β1 integrin and MCAM (CD146).
Matrix Biology, 38: 69-83 (2014)④Ishikawa T, Wondimu Z, Oikawa Y, Ingerpuu S, Virtanen I and Patarroyo M: Monoclonal antibodies to humanlaminin α4 chain globular domain inhibit tumor cell adhesion and migration on laminin 411 and 421, andbinding of α6β1 integrin and MCAM to α4-laminins. Matrix Biology, 36: 5-14 (2014)⑤文部科学省科学研究費補助⾦ 基盤研究(C)「課題名：低体重出生に関わる苦味受容体を介した⻭周病原細菌の影響」（2020-04-01 – 2024-03-31）研究代表者