ISSN 1881ー4980

信 州 大 学 医 学 部 医 学 科・大 学 院 医 学 系 研 究 科・医 学 部 附 属 病 院 業 績 録

SCIENTIFIC ACHIEVEMENTS OF SHINSHU UNIVERSITY SCHOOL OF
MEDICINE, SHINSHU UNIVERSITY GRADUATE SCHOOL OF MEDICINE,
AND SHINSHU UNIVERSITY HOSPITAL
信州大学医学部医学科・大学院医学系研究科・医学部附属病院業績録

No.47 (2018)

第四七号（二〇一八）
二〇一九

2019

信大
州学
大医
学学
医部
学業
部績
業録
績編
録集
編要
集項
要（
項抜粋）
信州
（平成28年12月29日改正）

１．収録対象 ２．収録対象
 信州大学医学部医学科・大学院医学系研究科・医学部附属病院及び出版委員会で信州大学医学部医学科・大学院医学系研究科・医学部附属病院及び出版委員会で認めた施設等に所属する者（当該年に在籍した者全員）認めた施設等に所属する者（当該年度に在籍した者全員）
２．収録内容 ３．収録内容
収録対象は、本文が欧文で執筆された研究業績とし、次の３項目に分ける。
研究業績を次の２項目に分ける。
１）論文
１）論文
原著、綜説、展望、症例報告、速報、予報で、査読のある学術雑誌に発表のもの。
原著、綜説、展望、症例報告、速報、予報で学術雑誌に発表のもの。
学術集会記録（全国的又は世界的規模の集会記録で、原著論文と同様の内容をも
学術集会記録（全国的又は世界的規模の集会記録で、原著論文と同様の内容をもち、ち、別刷が発行されているもの）
別刷が発行されているもの）
２）著書
２）著書
単行書、分担執筆。
単行書、分担執筆。
３）その他
治療指針、トピックス、事典等、専門的知見にもとづき執筆された、論文形式の
ただし、以下のものは除外する。
記事（イ）学会発表の抄録（邦文、欧文を問わない。論文型式をとっていても学会発表に関するもの及び１頁ものの速報は抄録とみなす）
ただし、以下のものは除外する。
（ロ）セミナー、シンポジウム、その他の講演のテキストないし記録。
（イ）学会発表の抄録（邦文、欧文を問わない。論文型式をとっていても学会発表（ハ）業務報告書（文部科学省、厚生労働省、その他助成機関への研究報告書）
に関するもの及び１頁ものの速報は抄録とみなす）（ニ）座談会記事。
（ロ）セミナー、シンポジウム、その他の講演のテキストないし記録。
（ホ）学会記。
務報告書（文部科学省、厚生労働省、その他助成機関への研究報告書）（ハ）業and（ヘ）質疑応答（ＱＡ）、治療指針、問題集の解説、トピックス、話題、グラビア、
（ニ）
座
談会記事。
事典等に類するもの。
（ホ）学会記。
（ト）新聞記事、教育に関する記事、人物紹介、書評、随筆など学術性が認められ（ヘ）論文形式をとらない質疑応答（Q and A）、問題集の解説、話題、グラビア等ないもの。
に類するもの。
（チ）著者表示が団体名で個人の著者性が認められないもの。
（ト）新聞・週刊誌記事、教育に関する記事、人物紹介、書評、随筆など学術性が（リ）学術雑誌とは認められないものに発表したもの。
認められないもの。
（ヌ）訳本及び訳論文。
（チ）著者表示が団体名で個人の著者性が認められないもの。
４．収録期間
毎年１月～12月

あ

と

が

き

信州大学医学部医学科・大学院医学系研究科・医学部附属病院業績録第47号をお届けします。
本業績録は過去１年間、各教室や部門などでなされた４つの活動（研究活動、教育活動、診
信州大学医学部医学科・大学院医学系研究科・医学部附属病院業績録第 38 号をお届けします。
療活動、社会貢献）のうち、研究活動の成果として公表された論文を中心にまとめたものです。
自己点検、自己評価、学内・学外への報告において、本業績録の役割は重要と思われます。こ
本業績録は過去１年間、各講座や部門等でなされた４つの活動（研究、教育、診療、社会貢献）の１年の研究活動を振り返り、今後の方向性を考える契機にしていただければ幸いです。
のうち、研究活動の成果として公表された論文を中心にまとめたものです。自己点検、自己評
学術論文が公表されるまでには大変なエネルギーが必要となります。各著者の研究は、医学
価、学内外への報告において、本業績録の果たす役割は重要と思われます。このような観点から、医療における問題や疑問から解明したい目的を定め、その目的を達成するために具体的研究計
この１年間の研究活動を振り返り、今後の方向性等を考える契機にしていただけたら幸いに存画を立て、資金を調達し、倫理審査を受け、実験あるいは臨床研究を行ってデータを集め、デーじます。
タと対峙し考え、人にいかにわかりやすく伝えるかを熟考しながら執筆し、投稿先を定め、査読を受け、査読者と編集委員長と議論を重ねて内容を深めて承諾を受け、晴れて学術論文として日の目を見ます。2018年度の医学部の英文論文数は491本でした。研究経費確保の困難さ、今年度の英文論文総数は昨年度より微減し、90 年度以降で最も少ない 386 という結果となり
人員不足、診療業務の増加など研究活動にかけるエフォート確保が難しい中で、少しずつそのました。しかしながら、単なる総数のみの評価が必ずしも適切であるとは言えず、今年度の業論文業績総数が増加していることにつき、すべての信州大学医学部の著者に敬意を表します。
出版委員として、公表された論文それぞれに著者のエネルギーが凝縮されていることを感じな
績の中には極めて質の高い研究成果も少なくありません。今日、卒業生の大学離れや医学科入がら、業績録への記録の是非をチェックさせていただきました。
学定員数増加等により、診療や教育活動等の業務負荷は増加の一途にあります。このような現粗悪学術誌（いわゆるハゲタカジャーナル）が問題となっております。学術業績の高い研究状ではありますが、研究活動は大学が大学であるための大きな責務であり、外部評価基準の重者の下には、日々そのような雑誌への投稿や原稿査読の依頼が届いていることと思います。今回の業績チェックでも、そのような雑誌や雑誌社に該当しないかをしっかりと評価いたしまし
要項目であることは言うまでもありません。今後、各講座・部門等でのさらなる研究の発展をた。信州大学「オープンアクセスジャーナル投稿ガイドライン」https://www.shinshu-u.ac.jp/
祈念致します。
hq/research-integrity/news/asset_items/74yakubu_07.pdfをご投稿や査読前にぜひご参照下さい。
世界中で新型コロナウイルス感染症が深刻化して、教育・診療・研究ほか、あらゆる面で行
最後に、本業績録の編集にあたりご尽力頂きました先生方、図書館職員の方々に厚く御礼申
動制限が要されております。このような時こそ、信州大学医学部として根拠に基づいた学術活動を行い社会貢献に努めるべきと強く思います。
し上げます。
最後に、本業績録の編集にあたりご尽力頂きました先生方、図書館職員の方々に厚く御礼申
浅村英樹
し上げます。
 出 版 委 員 長：浅村英樹
杠 俊介
出 版 委 員：奥山隆平、石田文宏、川股知之
出 版 委 員 長：杠 俊介
出医学部図書館主査：石坂憲司
版 委 員：古庄知己、和田有子、小山淳一
医 学 部 図 書 館：後閑壮登

信州大学医学部医学科・大学院医学系研究科
・医学部附属病院業績録 第
第 47
38 号
号
平成
年１月
28 日印刷日印刷
令和 23
2年
6 月 19平成年１月
28 日発行日発行
令和 23
2年
6 月 19
編集兼 信 州 大 学 医 学 部
発行者 松本市旭 3 丁目 1 の 1
印刷所

藤原印刷株式会社

松本市新橋 7 の 21 番地

a

SCIENTIFIC ACHIEVEMENTS OFSHINSHU UNIVERSITY SCHOOL OF MEDICINE,SHINSHU UNIVERSITY GRADUATE SCHOOL OF MEDICINE,
AND SHINSHU UNIVERSITY HOSPITAL

信州大学医学部医学科・大学院医学系研究科・
医学部附 属 病 院 業 績 録
No. 47( 2 0 1 8 )

2019

b

1

I. Scientific Achievements of Shinshu University School of Medicine,
Shinshu University Graduate School of Medicine,and Shinshu University HospitalContents
Aging Biology...............................................................3

Neurosurgery...............................................................21

Molecular Pathology.....................................................3

Dentistry & Oral Surgery............................................22

Metabolic Regulation....................................................4

Urology.......................................................................23

Cardiovascular Research...............................................4

Ophthalmology...........................................................23

Sports Medical Sciences...............................................4

Otorhinolaryngology...................................................24

Histology and Embryology...........................................5

Obstetrics and Gynecology.........................................24

Anatomy........................................................................5

Anesthesiology and Resuscitology.............................25

Physiology....................................................................5

Plastic and Reconstructive Surgery............................25

Molecular Cellular Physiology.....................................5

Laboratory Medicine...................................................26

Biochemistry and Molecular Biology...........................5Emergency and Critical Care Medicine......................28

Molecular Pharmacology..............................................6

Comprehensive Cancer Therapy.................................28

Pathology......................................................................6

Infection and Host Defense.........................................29

Pathobiology.................................................................6

Brain Disease Research...............................................29

Microbiology and Immunology....................................7

Innovation of Medical and Health Sciences Research

Medical Genetics..........................................................7................................................................................30

Preventive Medicine and Public Health........................8

Hearing Implant Sciences...........................................30

Legal Medicine.............................................................8

General Medicine........................................................30

Internal Medicine 1.......................................................8Radiology Division.....................................................30

Internal Medicine 2.......................................................8

Blood Transfusion Center...........................................31

Internal Medicine 3.....................................................11

Medical Informatics ...................................................31

Internal Medicine 4.....................................................13

Center for Medical Genetics.......................................31

Internal Medicine 5.....................................................13

Intractable Disease Care Center..................................31

Psychiatry....................................................................14

Neuroendovascular Therapy Center...........................31

Pediatrics.....................................................................15

Advence Center for Cellular Therapy.........................31

Dermatology...............................................................16

Cochlear Implant Center.............................................31

Radiology....................................................................17

Department of Pharmacy............................................32

Surgery 1.....................................................................18

Medical Safety Management Room............................32

Surgery 2.....................................................................18

Animal Research.........................................................32

Orthopaedic Surgery...................................................18

2

3

Aging Biology
20180001
Huo J, Xu Z, Hosoe K, Kubo H, Miyahara H,
Dai J, Mori M, Sawashita J, Higuchi K : Coenzyme Q10
Prevents Senescence and Dysfunction Caused by Oxidative
Stress in Vascular Endothelial Cells. Oxid Med Cell Longev: 3181759, 2018.
20180002
Yang M, Liu Y, Dai J, Li L, Ding X, Xu Z, Mori
M, Miyahara H, Sawashita J, Higuchi K : Apolipoprotein
A-II induces acute-phase response associated AA
amyloidosis in mice through conformational changes ofplasma lipoprotein structure. Sci Rep 8: 5620, 2018.
20180003
Miyahara H, Sawashita J, Ishikawa E, Yang
M, Ding X, Liu Y, Hachiya N, Kametani F, Yazaki M,
Mori M, Higuchi K : Comprehensive proteomic profiles ofmouse AApoAII amyloid fibrils provide insights into theinvolvement of lipoproteins in the pathology of amyloidosis.
J Proteomics 172: 111-121, 2018.
20180004
Ding X, Liu Y, Yang M, Li L, Miyahara H,
Dai J, Xu Z, Matsumoto K, Mori M, Higuchi K, Sawashita
J : Amyloidosis-inducing activity of blood cells in mouse
AApoAII amyloidosis. Exp Anim 67: 105-115, 2018.

Molecular Pathology
20180005
Kawakubo M, Horiuchi K, Matsumoto T,
Nakayama J, Akamatsu T, Katsuyama T, Ota H, Sagara J :Cholesterol-α-glucosyltransferase gene is present in most
Helicobacter species including gastric non-Helicobacter
pylori helicobacters obtained from Japanese patients.
Helicobacter 23: e12449, 2018.
20180006
Yoshizawa T, Mizumoto S, Takahashi Y,
Shimada S, Sugahara K, Nakayama J, Takeda S, Nomura Y,
Nitahara-Kasahara Y, Okada T, Matsumoto K, Yamada S,
Kosho T : Vascular abnormalities in the placenta of Chst14/- fetuses: implications in the pathophysiology of perinatal
lethality of the murine model and vascular lesions in human
CHST14/D4ST1 deficiency. Glycobiology 28: 80-89, 2018.
20180007
Sugiura Y, Kanda H, Motoi N, Nomura K,
Inamura K, Okada E, Matsumoto H, Shimoji T, Matsumoto
S, Nakayama J, Takazawa Y, Ishikawa Y, Machinami R :Osteosarcoma arising in fibrous dysplasia, confirmed bymutational analysis of GNAS gene. Pathol Res Pract 214:318-324, 2018.
20180008
Hanaoka T, Kurai M, Okada M, Ishizone S,
Karasawa F, Iizuka A, Ikeyama M, Nakayama J : Pulmonary

adenocarcinoma possibly developed from the cut-end
of small-sized adenocarcinoma in the lung periphery as
recurrence 13 years after its wedge resection. Surg Case Rep
4: 2, 2018.
20180009
Fuke M, Narita M, Wada Y, Seto T, Okada K,
Nakayama J, Izumi H, Ito KI : Increased Expression of
Y-Box-Binding Protein-1 in Hind-Limb Muscles During
Regeneration from Ischemic Injury in Mice. Tohoku J Exp
Med 244: 53-62, 2018.
20180010
Yamanoi K, Nakayama J : Reduced αGlcNAc
glycosylation on gastric gland mucin is a biomarker
of malignant potential for gastric cancer, Barrett's
adenocarcinoma, and pancreatic cancer. Histochem Cell Biol
149: 569-575, 2018.
20180011
Desamero MJ, Kakuta S, Chambers JK, Uchida
K, Hachimura S, Takamoto M, Nakayama J, Nakayama
H, Kyuwa S : Orally administered brown seaweed-derived
β-glucan effectively restrained development of gastric
dysplasia in A4gnt KO mice that spontaneously develop
gastric adenocarcinoma. Int Immunopharmacol 60: 211-220,2018.
20180012
Tanaka Y, Nakayama J : Upregulated expressionof La ribonucleoprotein domain family member 6 andcollagen type I gene following water-filtered broadspectrum near-infrared irradiation in a 3-dimensional humanepidermal tissue culture model as revealed by microarray
analysis. Australas J Dermatol 59: e87-e92, 2018.
20180013
Yamanoi K, Ishii K, Tsukamoto M, Asaka
S, Nakayama J : Gastric gland mucin-specific O-glycan
expression decreases as tumor cells progress from lobular
endocervical gland hyperplasia to cervical mucinous
carcinoma, gastric type. Virchows Arch 473, 305-311, 2018
473: 305-311, 2018.
20180014
Ya m a d a S , M a t s u u r a H , N a k a y a m a J :Limitation in defining ablation line by maginified
endoscopic imaging for endoscopic submucosal resection ofgastric adenocarcinoma of fundic gland type as revealed by
3D redonstruction images of gastric tissue specimens. J Can
Assoc Gastroenterol 1: 137-138, 2018.
20180015
Uehara M, Kosho T, Yamamoto N, Takahashi
HE, Shimakura T, Nakayama J, Kato H, Takahashi J : Spinal
manifestations in 12 patients with musculocontractural
Ehlers-Danlos syndrome caused by CHST14/D4ST1
deficiency (mcEDS-CHST14). Am J Med Genet 176A:
2331-2341, 2018.

4

Metabolic Regulation
20180016
Takahashi S, Tanaka N, Fukami T, Xie C,
Yagai T, Kim D, Velenosi TJ, Yan T, Krausz KW, Levi M,
Gonzalez FJ : Role of Farnesoid X Receptor and Bile Acids
in Hepatic Tumor Development. Hepatol Commun 2: 15671582, 2018.
20180017
Guo X, Kashihara T, Nakada T, Aoyama T,
Yamada M : PDGF-induced migration of synthetic vascularsmooth muscle cells through c-Src-activated L-type Ca2+
channels with full-length CaV1.2 C-terminus. Pflugers Arch470: 909-921, 2018.
20180018
Kimura T, Tanaka N, Fujimori N, Sugiura A,
Yamazaki T, Joshita S, Komatsu M, Umemura T, Matsumoto
A, Tanaka E : Mild drinking habit is a risk factor forhepatocarcinogenesis in non-alcoholic fatty liver disease
with advanced fibrosis. World J Gastroenterol 24: 14401450, 2018.
20180019
Komatsu M, Tanaka N, Kimura T, Fujimori
N, Sano K, Horiuchi A, Sugiura A, Yamazaki T, Shibata S,
Joshita S, Umemura T, Matsumoto A, Tanaka E : Miglitol
attenuates non-alcoholic steatohepatitis in diabetic patients.
Hepatol Res 48: 1092-1098, 2018.
20180020
Fujimori N, Umemura T, Kimura T, Tanaka
N, Sugiura A, Yamazaki T, Joshita S, Komatsu M, Usami
Y, Sano K, Igarashi K, Matsumoto A, Tanaka E : Serum
autotaxin levels are correlated with hepatic fibrosis andballooning in patients with non-alcoholic fatty liver disease.
World J Gastroenterol 24: 1239-1249, 2018.
20180021
Makino T, Horiuchi A, Kajiyama M, Tanaka N,
Sano K, Maetani I : Delayed Bleeding Following Cold Snare
Polypectomy for Small Colorectal Polyps in Patients Taking
Antithrombotic Agents. J Clin Gastroenterol 52: 502-507,
2018.
20180022
Wakabayashi SI, Kimura T, Tanaka N, Joshita
S, Kawata K, Umemura T, Hiroshima Y, Mori H, Kobayashi
H, Wada S, Tanaka E : Emergence of anti-mitochondrial
M2 antibody in patient with angioimmunoblastic T-cell
lymphoma. Clin J Gastroenterol 11: 302-308, 2018.
20180023
Fujii F, Kimura T, Tanaka N, Kubota D, Sugiura
A, Umemura T, Wada S, Tanaka E : Hepatic Angiosarcoma
with Kasabach-Merritt Phenomenon: A Case Report andReview of the Literature. Ann Hepatol 17: 655-660, 2018.
20180024

Yamashita Y, Kimura T, Tanaka N, Yazaki M,

Itagaki T, Joshita S, Umemura T, Matsumoto A, Mori H,
Wada S, Tanaka E : Salmonella Enteritidis cholecystitis withchronic granulomatous disease. IDCases 12: 49-52, 2018.

Cardiovascular Research
20180025
Zhai L, Sakurai T, Kamiyoshi A, IchikawaShindo Y, Kawate H, Tanaka M, Xian X, Hirabayashi K, Dai
K, Cui N, Tanimura K, Liu T, Wei Y, Tanaka M, Tomiyama
H, Yamauchi A, Igarashi K, Shindo T : Endogenous
calcitonin gene-related peptide suppresses ischemic brain
injuries and progression of cognitive decline. J Hypertens.
36: 876-891, 2018.
20180026
Liu T, Kamiyoshi A, Tanaka M, Iida S, Sakurai
T, Ichikawa-Shindo Y, Kawate H, Hirabayashi K, Dai K,
Cui N, Tanaka M, Wei Y, Nakamura K, Matsui S, Yamauchi
A, Shindo T : RAMP3 deficiency enhances postmenopausal
obesity and metabolic disorders. Peptides. 110: 10-18, 2018.

Sports Medical Sciences
20180027
Uchida K, Kamijo Y, Ikegawa S, Masuki S,
Nose H : Interval walking training and nutritional intake toincrease plasma volume in elderly. Med Sci Sports Exerc 50:
151-158, 2018.
20180028
Tanabe A, Masuki S, Nemoto K, Nose H :Seasonal influence on adherence to and effects of an interval
walking training program on sedentary female college
students in Japan. Int J Biometeorol 62: 634-654, 2018.
20180029
Suzuki H, Masuki S, Morikawa A, Ogawa
Y, Kamijo Y, Takahashi K, Nakajima M, Nose H : Effectsof 5-aminolevulinic acid supplementation on home-based
walking training achievement in middle-aged depressive
women: randomized, double-blind, crossover pilot study .
Sci Rep 8: 7151-―, 2018.
20180030
Morikawa M, Nakano S, Mitsui N, Murasawa
H, Masuki S, Nose H : Effects of dried tofu supplementation
during interval walking training on the methylation of the
NFKB2 gene in the whole blood of older women. J Physiol
Sci 68: 749-757, 2018.
20180031
Nose H, Kamijo Y, Masuki S : Interactions
between body fluid homeostasis and thermoregulation inhumans. Handb Clin Neurol 156: 417-429, 2018.
20180032
Kamijo Y, Okazaki K, Ikegawa S, Okada Y,
Nose H : Rapid saline infusion and/or drinking enhanceskin sympathetic nerve activity components reduced byhypovolaemia and hyperosmolality in hyperthermia. J

5Physiol (Lond) 596: 5443-5459, 2018.
20180033
Horiuchi M, Endo H, Handa Y, Nose H :Barometric pressure change and heart eate responses during
sleeping at 3000m. Int J Biometeorol 62: 909-912, 2018.

Histology and Embryology
20180034
Sakai S, Tomotsune D, Hirashima K, Takizawa
S, Yokoyama T, Yue F, Tani R, Matsumoto K, Sasaki K :Simulation of Embryonic Environments Produced by the
Effect of Estradiol on Induced Pluripotent Stem Cells. J
Regen Med 7: 1-5, 2018.
20180035
G e n o v a E , P e l i n M , S a s a k i K , Yu e F,
Lanzi G, Masneri S, Ventura A, Stocco G, Decorti G :Induced Pluripotent Stem Cells as a Model for Therapy
Personalization of Pediatric Patients: Disease Modeling andDrug Adverse Effects Prevention. Curr Med Chem 25: 28262839, 2018.
20180036
Hirashima K, Yue F, Tomotsune D, Sasaki K :Earlobe-like peritoneal appendage near the angle of His: a
useful landmark for demarcating the lateral margin of thegastric cardia. Anat Sci Int 93: 82-87, 2018.

Anatomy20180037
Karasawa M, Yokouchi K, Kawagishi K,
Moriizumi T, Fukushima N : Effects of repeated nerve
injuries at different time intervals on functional recovery andnerve innervation. J Clin Neurosci 48: 185-190, 2018.

20180041
Nakano A, Kawashima H, Miyake Y, Zeniya
T, Yamamoto A, Koshino K, Temma T, Fukuda T, Fujita
Y, Kakino A, Kanaya S, Sawamura T, Iida H : 123I-labeled
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Molecular Cellular Physiology
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Physiology
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20180047
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Biochemistry and Molecular Biology
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6

Molecular Pharmacology

20180058
Kobayashi M, Sakai Y, Kariya Y, Sakai H,
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20180050
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20180059
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20180052
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Pathobiology
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7

20180066
Cho K, Yamada M, Agematsu K, Kanegane
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Microbiology and Immunology
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Medical Genetics
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Morokawa H, Kamiya M, Wakui K, Kobayashi
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Preventive Medicine and Public Health20180082
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Masahito Hitosugi, Misa Tojo, Masateru
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Legal Medicine
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Takahashi F, Kobayashi M, Kobayashi A,
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Internal Medicine 1
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Yasuo M, Kitaguchi Y, Kinota F, Kosaka
M, Urushihata K, Ushiki A, Yamamoto H, Kawakami S,
Hanaoka M : Usefulness of the forced oscillation techniquein assessing the therapeutic result oftracheobronchial central
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Kato A, Yasuo M, Tokoro Y, Kobayashi T,
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H, Hanaoka M : Virtual bronchoscopic navigation as an aid
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20180090
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G, Hanaoka M : Bevacizumab-induced tracheoesophageal
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Hanaoka M, Nakamura H, Aoshiba K : DrugInduced Lung Injury. Springer, Berlin, 2018.
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Internal Medicine 2
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Fujii F, Kimura T, Tanaka N, Kubota D, Sugiura
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Fujimori N, Umemura T, Kimura T, Tanaka
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Y, Sano K, Igarashi K, Matsumoto A, Tanaka E : Serum
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Hara Y, Sonoda K, Hashimoto K, Fuji K,
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Harada M, Ichikawa T, Kobayashi M : Onset
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Harada M, Miyashita Y, Ichikawa T, Kobayashi
M : A Case of Rapid Progressive Kidney Dysfunction with
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Isoda A, Murayama K, Ito S, Kohara Y, Iino M,
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Mitsumori T, Kirito K, Chou T, Murakami H, Kanshinetsu
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Ito A, Suga T, Ota H, Tateiwa N, Matsumoto
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Joshita S, Ichikawa Y, Umemura T, Usami Y,
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M, Matsumoto A, Igarashi K, Ota M, Tanaka E : Serum
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Joshita S, Umemura T, Tanaka E, Ota M :Genetics and epigenetics in the pathogenesis of primarybiliary cholangitis. Clin J Gastroenterol 11: 11-18, 2018.
20180104
Joshita S, Umemura T, Usami Y, Yamashita Y,
Norman GL, Sugiura A, Yamazaki T, Fujimori N, Kimura T,
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Kawakami T, Nakazawa H, Kurasawa Y, Sakai
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20180109
Kimura T, Tanaka N, Fujimori N, Sugiura A,
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20180110
Komatsu M, Tanaka N, Kimura T, Fujimori
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Nakajima T, Uehara T, Kobayashi Y, Kinugawa
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Nakamura A, Ozawa M, Watanabe T, Ito T,
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Nakazawa H, Nishina S, Sakai H, Ito T,
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Nakazawa H, Nishina S, Senoo Y, Sakai
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Okamura T, Iwaya Y, Kitahara K, Suga T,
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20180118
Saito H, Hirayama A, Umemura T, Joshita S,
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11

20180126
Wakabayashi SI, Kimura T, Tanaka N, Joshita
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20180127
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20180128
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Yamazaki T, Joshita S, Kasuga E, Horiuchi
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20180130
Yamazaki T, Joshita S, Umemura T, Usami Y,
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20180138
Harada M, Motoki H, Kashima Y, Nakamura C,
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20180131
Yamazaki T, Umemura T, Joshita S, Yoshizawa
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20180139
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20180132
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20180140Ishida M, Yamada Y, Mizutani T, Hara A,
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20180133
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20180134
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20180141
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20180143
Kobayashi M, Sakai Y, Kariya Y, Sakai H,
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20180144
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20180145
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20180146
Mizobe Y, Miyatake S, Takizawa H, Hara
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20180147
Nakamura A, Aoki Y, Tsoumpra M, Yokota
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20180148
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20180150
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20180153
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20180154
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20180155
Shimazaki C, Hata H, Iida S, Ueda M, Katoh
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20180156
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20180157
Tanaka R, Shimojima Y, Moteki H, Kishida
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20180158
Tanihata J, Nagata T, Ito N, Saito T, Nakamura
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20180159
Usuda M, Kodaira M, Ogawa Y, Kanbayashi T,
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Yazaki M, Yoshinaga T, Sekijima Y, Kametani
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20180161

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13

G, Hatano T, Machida Y, Shimo Y, Hayashida A, Ikeda A,
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Nishio S, Sekido T, Ohkubo Y, Oiwa A,
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Sakurai K, Kawai Y, Yamazaki M, Komatsu M :Prediction of lowest nocturnal blood glucose level based on
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Buse JB, Carlson AL, Komatsu M, Mosenzon
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Aizawa T, Komatsu M : KATP ChannelIndependent Pathway and the Glucoreceptor. In: Kojima,
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20180171
Minamisawa M, Miura T, Motoki H, Ueki Y,
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20180172
Nakagawa Y, Nishikimi T, Sakai H, Ohno
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20180173
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20180174
Miura T, Miyashita Y, Soga Y, Hozawa K,
Doijiri T, Ikeda U, Kuwahara K on behalf of the DEBATEin SFA investigators : Drug-Eluting Versus Bare-Metal Stent
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Kuwahara K, Nakagawa Y, Nishikimi T :Cutting Edge of Brain Natriuretic Peptide (BNP) Research-The Diversity of BNP Immunoreactivity and Its ClinicalRelevance-. Circ J 82: 2455-2461, 2018.

20180168
Okada A, Shoda M, Tabata H, Shoin W,
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20180176
Harada M, Motoki H, Kashima Y, Nakamura C,
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20180169
Ebisawa S, Ueki Y, Mochidome T, Senda K,
Nishimura H, Saigusa T, Miura T, Motoki H, Koyama J,
Ikeda U : Comparison of platelet aggregation response inswitching regimen from prasugrel to clopidogrel between

20180177
Minamisawa M, Koyama J, Kozuka A, Miura
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20180178
Yamamoto S, Ishida T, Misawa K, Ohira M,
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20180185
Hori H, Nakamura S, Yoshida F, Teraishi T,
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20180179
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Y, Kuwahara K, Kato T, Kimura T, on behalf of the KCHF
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20180186
Iizawa M, Tanabe H, Takahashi T, Ohya
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20180180
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20180181
Kuwabara J, Kuwahara K, Kuwabara Y, Yasuno
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Imamura H, Kamijo H, Nitta K, Okada
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Hidese S, Asano S, Saito K, Sasayama D,
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20180184
Hidese S, Ota M, Sasayama D, Matsuo J, Ishida
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20180187
Ishii T, Hattori K, Miyakawa T, Watanabe K,
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20180188
Ishiwata S, Hattori K, Sasayama D, Teraishi T,
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20180190
M u t a i H , F u r u k a w a T, Wa k a b a y a s h i A ,Suzuki A, Hanihara T : Functional outcomes of inpatient
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20180192
Sasayama D, Hattori K, Ogawa S, Yokota Y,
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20180193

Teraishi T, Kajiwara M, Hori H, Sasayama D,

15

Hidese S, Matsuo J, Ishida I, Kajiwara Y, Ozeki Y, Ota M,
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Yoon HS, Hattori K, Sasayama D, Kunugi
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Pediatrics

20180204
Takeuchi Y, Seki T, Kobayashi N, Sano K,
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20180195
Hachiya A, Kobayashi N, Matsuzaki S,
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2018.
20180197
Nakamura C, Inaba Y, Tsukahara K, Mochizuki
M, Sawanobori E, Nakazawa Y, Aoyama K : A pediatric casewith peripheral facial nerve palsy caused by a granulomatous
lesion associated with cat scratch disease. Brain Dev 40:
159-162, 2018.
20180198
Miyosawa Y, Akazawa Y, Kamiya M, Nakamura
C, Takeuchi Y, Kusakari M, Nakamura T : Presepsin as apredictor of positive blood culture in suspected neonatal
sepsis. Pediatr Int 60: 157-161, 2018.
20180199
M a t s u o k a D , H i d a k a Y, K u r o z u m i M ,Tsukahara Y, Nakazawa Y : Childhood asymptomatic renalarteriovenous fistula 5 years after renal biopsy. Pediatr Int
60: 601-602, 2018.
20180200
Ya n a g i s a w a T, S a i t o S , K a t s u y a m a Y,
Hirabayashi K, Shigemura T, Tanaka M, Sakashita
K, Nakazawa Y : Successful induction of therapeuticurinaryconcentration by intravenous ganciclovir and oralvalganciclovir with remission of adenoviral hemorrhagic
cystitis after cord blood transplantation. PediatrTransplant
22: e13241, 2018.
20180201
Shigemura T, Nakazawa Y, Yoshikawa T, Fujii
H, Yamada S, Saijo M, Okuyama R : Severe acyclovirresistant herpes simplex virus 1 infection following cord
blood transplantation. Int J Hematol 108: 237-238, 2018.

20180205
Morokawa H, Kamiya M, Wakui K, Kobayashi
M, Kurata T, Matsuda K, Kawamura R, Kanno H,
Fukushima Y, Nakazawa Y, Kosho T : Myelodysplastic
syndrome in an infant with constitutional pure duplication
1q41-qter. Hum Genome Var 5: 6, 2018.
20180206
Akazawa Y, Yamazaki S, Obinata H, Hachiya A,
Kamiya M, Motoki N, Nakamura T : Decreased Circulating
Insulin-Like Growth Factor 1 Levels Are Associated
withCardiac Diastolic Dysfunction in Small for Gestational
Age Infants. Am J Perinatol 35: 1178-1185, 2018.
20180207
N i s h i o k a M , I n a b a Y, M o t o b a y a s h i M ,Hara Y, Numata R, Amano Y, Shingu K, Yamamoto Y,
Murayama K, Ohtake A, Nakazawa Y : An infant case ofdiffusecerebrospinal lesions and cardiomyopathy caused by
a BOLA3 mutation. Brain Dev 40: 484-488, 2018.
20180208
Yanagisawa T, Nakamura T : Survey of
hospitalization for respiratory syncytial virus in Nagano,
Japan. Pediatr Int 60: 835-838, 2018.
20180209
Ya n a g i s a w a R , O g i s o Y, F u r u k a w a T :Neuroblastoma invading the kidney through the renal hilum.
Clin Exp Nephrol 22: 196-198, 2018.
20180210
K u r a t a T, M a t s u d a K , H i r a b a y a s h i K ,Shigemura T, Sakashita K, Nakahata T, Koike K :Panobinostat inhibits the proliferation of CD34+ CD38- cells
under stimulation of hematopoietic growth factors on AGMS3 cells in juvenile myelomonocytic leukemia. Pediatr
Blood Cancer 65: e27261, 2018.
20180211S a i t o S , O g i s o Y, S a k a s h i t a K :Lymphadenopathy with coexisting normal architecture inmalignant lymphoma. Int J Hematol 108: 463-464, 2018.

16

20180212
Nasuno M, Shigemura T, Nakazawa Y, Inaba
Y, Motobayashi M : Postencephalitic epilepsy secondary tocytomegalovirus encephalitis. Pediatr Int 60: 758-760, 2018.

myocardial infarction due to Kawasaki disease. Cardiol
Young. 6: 1-4, 2018.

Dermatology
20180213
Yanagisawa R, Kubota N, Hidaka E, Sakashita
K, Tanaka M, Nakazawa Y, Nakamura T : Cisplatin-induced
nephrotoxicity in patients with advanced neuroblastoma.
Pediatr Blood Cancer 65: e27253, 2018.
20180214
Shiba N, Inaba Y, Motobayashi M, Nishioka
M, Kawasaki Y, Noda S, Matsuura H, Kobayashi N,
Matsuoka T, Nakamura A, Nakazawa Y : A Pediatric Caseof Relapsing-Remitting Multiple Sclerosis Onset following
Varicella Zoster Ophthalmicus with Optic Neuritis. Case Rep
Pediatr 2018: 6931206, 2018.
20180215
Urayama KY, Takagi M, Kawaguchi T, Matsuo
K, Tanaka Y, Ayukawa Y, Arakawa Y, Hasegawa D, Yuza
Y, Kaneko T, Noguchi Y, Taneyama Y, Ota S, Inukai T,
Yanagimachi M, Keino D, Koike K, Toyama D, Nakazawa
Y, Kurosawa H, Nakamura K, Moriwaki K, Goto H,
Sekinaka Y, Morita D, Kato M, Takita J, Tanaka T, Inazawa
J, Koh K, Ishida Y, Ohara A, Mizutani S, Matsuda F, Manabe
A : Regional evaluation of childhood acute lymphoblastic
leukemia genetic susceptibility loci among Japanese. Sci
Rep 8: 789-789, 2018.
20180216
Mori M, Hara T, Kikuchi M, Shimizu H,
Miyamoto T, Iwashima S, Oonishi T, Hashimoto K,
Kobayashi N, Waki K, Suzuki Y, Otsubo Y, Yamada H,
Ishikawa C, Kato T, Fuse S : Infliximab versus intravenous
immunoglobulin for refractory Kawasaki disease: a phase 3,
randomized, open-label, active-controlled, parallel-group,
multicenter trial. Sci Rep 8: 1994-1994, 2018.
20180217
Cho K, Yamada M, Agematsu K, Kanegane
H, Miyake N, Ueki M, Akimoto T, Kobayashi N, Ikemoto
S, Tanino M, Fujita A, Hayasaka I, Miyamoto S, TanakaKubota M, Nakata K, Shiina M, Ogata K, Minakami H,
Matsumoto N, Ariga T : Heterozygous Mutations in OAS1
Cause Infantile-Onset Pulmonary Alveolar Proteinosis with
Hypogammaglobulinemia. Am J Hum Genet 102: 480-486,
2018.
20180218
Kobayashi J, Yanagisawa R, Ono T, Tatsuzawa
Y, Tokutake Y, Kubota N, Hidaka E, Sakashita K, Kojima
S, Shimodaira S, Nakamura T : Administration of plateletconcentrates suspended in bicarbonated Ringer's solution inchildren who had platelet transfusion reactions. Vox Sang
113: 128-135, 2018.
20180219
Akagawa D, Motoki N, Hachiya A, Akazawa
Y : Transient Q-waves in an infant with asymptomatic

20180220
Nakamura K, Yaguchi T, Ohmura G, Kobayashi
A, Kawamura N, Iwata T, Kiniwa Y, Okuyama R, Kawakami
Y : Involvement of local renin-angiotensin system in
immunosuppression of tumor microenvironment. Cancer Sci
109: 54-64, 2018.
20180221
Kobayashi M, Ogawa E, Okuyama R, Kanno
H : In vasculitis of small muscular arteries, activationof vessel-infiltrating CD8 T cells seems to be antigenindependent. Virchows Arch 472: 271-279, 2018.
20180222
Ogawa E, Okuyama R, Seki T, Kobayashi A,
Oiso N, Muto M, Nakagawa H, Kawada A : Epidemiologicalsurvey of patients with psoriasis in Matsumoto city, Nagano
Prefecture, Japan. J Dermatol 45: 314-317, 2018.
20180223
Ogawa E, Sato Y, Minagawa A, Okuyama R :Pathogenesis of psoriasis and development of treatment. J
Dermatol 45: 264-272, 2018.
20180224
Kiniwa Y, Nakamura K, Mikoshiba A, Akiyama
Y, Morimoto A, Okuyama R : Diversity of circulating tumor
cells in peripheral blood: Detection of heterogeneous BRAF
mutations in a patient with advanced melanoma by singlecell analysis. J Dermatol Sci 90: 211-213, 2018.
20180225
Yamamoto T, Ohtsuki M, Sano S, Igarashi
A, Morita A, Okuyama R, Wada M, Katoh N, Kawada A :Juvenile-onset psoriatic arthritis: a survey by the JapaneseSociety for Psoriasis Research. Eur J Dermatol 28: 419-421,
2018.
20180226
Edamitsu T, Uhara H, Minagawa A, Okuyama
R : Multiple Melanonychia Striata as a Sign of Connective
Tissue Disorders. J Am Acad Dermatol 79: 375-377, 2018.
20180227
Shigemura T, Nakazawa Y, Yoshikawa T, Fujii
H, Yamada S, Saijo M, Okuyama R : Severe acyclovirresistant herpes simplex virus 1 infection following cord
blood transplantation. Int J Hematol 108: 237-238, 2018.
20180228
Kobayashi A, Ogawa E, Matsuzaki S,
Minagawa A, Okuyama R : Pediatric case of generalized
pustular psoriasis developing acute pancreatitis. J Dermatol
45: 278-279, 2018.
20180229
Sato M, Uhara H, Koga H, Okuyama R :Efficacy and toxicity of ipilimumab used after nivolumab in17patients with melanoma. J Dermatol 45: 287-289, 2018.
20180230
Omodaka T, Kiniwa Y, Sato Y, Suwa M, Sato
M, Yamaguchi T, Sato A, Miyake T, Okuyama R : Type 1
diabetes in a melanoma patient treated with ipilimumab after
nivolumab. J Dermatol 45: 289-290, 2018.
20180231
Kato H, Itoh-Nakadai A, Matsumoto M, Ishii
Y, Watanabe-Matsui M, Ikeda M, Ebina-Shibuya R, Sato Y,
Kobayashi M, Nishizawa H, Suzuki K, Muto A, Fujiwara T,
Nannya Y, Malcovati L, Cazzola M, Ogawa S, Harigae H,
Igarashi K : Infection perturbs Bach2- and Bach1-dependent
erythroid lineage 'choice' to cause anemia. Nat Immunol 19:1059-1070, 2018.
20180232
Omodaka T, Minagawa A, Uhara H, Wakamatsu
K, Koizumi T, Yokokawa Y, Koga H, Okuyama R : Serum
5-S-cysteinyldopa behavior in the early phase of nivolumab
treatment of 12 melanoma patients. J Dermatol 45: 13401344, 2018.
20180233
Namikawa K, Kiyohara Y, Takenouchi T, Uhara
H, Uchi H, Yoshikawa S, Takatsuka S, Koga H, Wada N,
Minami H, Hatsumichi M, Asada S, Namba Y, Yamazaki
N : Efficacy and safety of nivolumab in combination with
ipilimumab in Japanese patients with advanced melanoma:
An open-label, single-arm, multicentre phase II study. Eur J
Cancer 105: 114-126, 2018.

Radiology
20180234
Kawakami S, Fujinaga Y, Yanagisawa S,
Kadoya M, Kobayashi A, Oguchi K : A case of pancreatic
carcinoma with bilateral hilar 18F-FCG and 67Ga hyper
accumulation. The Shinshu Medical Journal 66: 151-155,2018.
20180235
Ohya A, Asaka S, Fujinaga Y, Kadoya M :Uterine cervical adenocarcinoma associated with lobular
endocervical glandular hyperplasia: Radiologic-pathologic
correlation. J Obstet Gynaecol Res 44: 312-322, 2018.
20180236
Yamada A, Fujinaga Y, Suzuki T, Komatsu
D, Kitoh Y, Iwadate Y, Nozaki A, Ueda K, Kadoya M :Quantitative estimation of progression of chronic liverdisease using gadoxetate disodium-enhanced magnetic
resonance imaging. Hepatol Res 48: 735-745, 2018.
20180237
Yamada A, Okajima Y, Yoshizawa E, Fukamatsu
F, Mitsui T, Suzuki T, Ichinohe F, Oyama K, Todoroki K,
Maehara M, Aonuma T, Nonaka T, Fujinaga Y, Kadoya
M : Improvement in radiological reading efficiency andresidents' education and clinical contribution using themodified reading system "Triage Reader". Jpn J Radiol 36:
649-660, 2018.
20180238
Komatsu D, Yamada A, Suzuki T, Kurozumi
M, Fujinaga Y, Ueda K, Kadoya M : Compartment model
analysis of intravenous contrast-enhanced dynamic
computed tomography in hepatic hemodynamics: A
validation study using intre-arterial contrast-enhanced
computed tomography. Hepatol Res 48: 829-838, 2018.
20180239
Fukazawa A, Koiwai K, Ozawa T, Matsushita
H, Kadoya M : Predictive factors for deterioration of lower
urinary tract symptoms after Iodine-125 brachytherapy inprostate cancer patients. The Shinshu Medical Journal 66:
131-137, 2018.
20180240
Suzuki T, Yamada A, Komatsu D, Kurozumi M,
Fujinaga Y, Ueda K, Miyagawa S, Kadoya M : Evaluation of
splenic perfusion and spleen size using dynamic computed
tomography: Usefulness in assessing degree of liver fibrosis. Hepatol Res 48: 87-93, 2018.
20180241
Ishizaka N, Fujinaga Y, Hourai R, Fujisaka
T, Sohmiya K : Prevalence of elevated serum IgG4 level
among patients diagnosed or suspected with cardiovasculardisorders. Ann Vasc Dis 11: 496-502, 2018.
20180242
Moteki H, Fujinaga Y, Goto T, Usami S :Pneumolabyrinth, intracochlear and vestibular fluid loss
after cochlear implantation. Auris Nasus Larynx 45: 11161120, 2018.
20180243
Wada Y, Kitaguchi Y, Yasuo M, Ueno F,
Kawakami S, Fukushima K, Fujimoto K, Hanaoka M :Diversity of respiratory impedance based on quantitative
computed tomography in patients with COPD. Int J Chron
Obstruct Pulmon Dis 13: 1841-1849, 2018.
20180244
Yasuo M, Kitaguchi Y Kinota F, Kosaka
M, Urushihata K, Ushiki A, Yamamoto H, Kawakami S,
Hanaoka M : Usefulness of the forced oscillation techniquein assessing the therapeutic result of tracheobronchial central
airway obstruction . Respir Investig 56: 222-229, 2018.
20180245
Nishikawa A, Ogiwara T, Nagm A, Sano K,
Okada M, Chiba A, Agata M, Kaneko T, Tamada H, Uehara
T, Hongo K : Atypical teratoid/rhabdoid tumor of the sellar
region in adult women: Is it a sex-related disease?. J Clin
Neurosci 49: 16-21, 2018.
20180246
Usuda M, Kodaira M, Ogawa Y, Kanbayashi T,
Yanagisawa S, Sekijima Y : Letter to the Editor: Fluctuating
CSF hypocretin-1 levels in mild brain trauma-induced

18

Kleine-Levin syndrome. J Neurol Sci 391: 10-11, 2018.

Surgery 1
20180247
Motoyama H, Kobayashi A, Yokoyama T,
Shimizu A, Sakai H, Notake T, Fukushima K, Miyagawa
SI : Treatment with specific soluble factors promotes thefunctional maturation of transcription factor-mediated,pancreatic transdifferentiated cells. PLoS One. 13:
e0197175, 2018.
20180248
Takeuchi D, Koide N, Suzuki A, Shimizu F,
Koyama Y, Ehara T, Yamamoto Y, Koyama M, Nakamura
S, Kitazawa M, Miyagawa Y, Miyagawa S : High incidenceof other primary malignancies in patients with synchronous
multiple gastric cancers a multi-center retrospective cohort
study. Oncotarget. 9: 20605-20616, 2018.
20180249
Matsumura T, Hida S, Kitazawa M, Fujii C,
Kobayashi A, Takeoka M, Taniguchi SI, Miyagawa SI: Fascin1 suppresses RIG-I-like receptor signaling andinterferon-β production by associating with IκB kinase ϵ(IKKϵ) in colon cancer. J Biol Chem. 293: 6326-6336, 2018.
20180250
Yokoi K, Kobayashi A, Motoyama H, Kitazawa
M, Shimizu A, Notake T, Yokoyama T, Matsumura
T, Takeoka M, Miyagawa SI : Survival pathway ofcholangiocarcinoma via AKT/mTOR signaling to escape
RAF/MEK/ERK pathway inhibition by sorafenib. Oncol
Rep. 39: 843-850, 2018.
20180251
Muranaka F, Nakajima T, Iwaya M, Ishii K,
Higuchi K, Ogiwara N, Miyagawa S, Ota H : A Comparative
Immunohistochemical Study of Anal Canal Epithelium in
Humans and Swine, Focusing on the Anal Transitional Zone
Epithelium and the Anal Glands. Anat Rec (Hoboken). 301:
796-805, 2018.

Surgery 2
20180252
Fuke M, Narita M, Wada Y, Seto T, Okada
K, Nakayama J, Izumi H, Ito K : Increased Expression of
Y-Box-Binding Protein-1 in Hind-Limb Muscles During
Regeneration from Ischemic Injury in Mice. Tohoku J Exp
Med 244(1): 53-62, 2018.
20180253
Gomibuchi T, Seto T, Komatsu M, Tanaka H,
Ichimura H, Yamamoto T, Ohashi N, Wada Y, Okada K: Impact of Frailty on Outcomes in Acute Type A Aortic
Dissection. Ann Thorac Surg 106(5): 1349-1355, 2018.
20180254
Gomibuchi T, Okada K, Seto T, Okita Y : Valvesparing aortic root replacement after double-switch operation

for corrected transposition of the great arteries in a patientwith ulcerative colitis. J Thorac Cardiovasc Surg 155(6):175-176, 2018.
20180255
Kehara H, Wada Y, Fukui D, Shingu K,
Seto T, Okada K : Nontraumatic Proximal Ulnar Artery
Pseudoaneurysm Mimicking a Soft Tissue Tumor in Image
Modality. Ann Vasc Surg 47: 279(e1)-279(e5), 2018.
20180256
Sugitani I, Onoda N, Ito K, Suzuki S :Management of Anaplastic Thyroid Carcinoma: the Fruits
from the ATC Research Consortium of Japan. J Nippon Med
Sch 85(1): 18-27, 2018.
20180257
Oba T, Ito K : Combination of two anti-tublin
agents, eribulin and paclitaxel, enhances anti-tumor effects
on triple-negative breast cancer through mesenchymalepithelial transition. Oncotarget 9(33): 22986-23002, 2018.
20180258
Oba T, Ono M, Iesato A, Hanamura T, Watanabe
T, Ito T, Kanai T, Maeno K, Ito K : Chylous leakage after
axillary lymph node dissection in a patient with breast
cancer. Breast J 24(3): 438-440, 2018.
20180259
Sakaizawa T, Matsumura T, Fujii C, Hida
S, Toishi M, Shiina T, Yoshida K, Hamanaka K, Ito K,
Taniguchi S : Potential Role of ASC, a Proapoptotic Protein,for Determining the Cisplatin Susceptibility of Lung Cancer
Cells. Tohoku J Exp Med 244(2): 133-144, 2018.
20180260
Hamanaka K, Koyama T, Matsuoka S, Takeda
T, Miura K, Yamada K, Hyogotani A, Seto T, Okada K, Ito
K : Analysis of surgical treatment of Masaoka stage IIIIV thymic epithelial tumors. Gen Thorac Cardiovasc Surg
66(129): 731-735, 2018.
20180261
Hamanaka K, Takeda T, Ohashi M, Kumeda
H, Agatsuma H, Shimada K, Maruyama K, Yoshida K,
Nakamura T : Thoracoscopic resection of a cystic seminomaof the mediastinum. Asian J Endosc Surg : , 2018.
20180262
Miura K, Hamanaka K, Matsuoka S, Takeda T,
Agatsuma H, Hyogotani A, Ito KI, Nishimaki F, Koizumi
T, Uehara T : Primary mediastinal dedifferentiatedliposarcoma: Five case reports and a review. Thorac Cancer
9(12): 1733-1740, 2018.

Orthopaedic Surgery
20180263
Takizawa T, Nakayama N, Haniu H, Aoki K,
Okamoto M, Nomura H, Tanaka M, Sobajima A, Yoshida K,
Kamanaka T, Ajima K, Oishi A, Kuroda C, Ishida H, Okano
S, Kobayashi S, Kato H, Saito N : Titanium Fiber Plates for19

Bone Tissue Repair. Adv Mater. 30(4): 1703608, 2018.
20180264
Murai T, Uchiyama S, Nakamura K, Ido
Y, Hata Y, Kato H : Functional range of motion in themetacarpophalangeal joints of the hand measured by single
axis electric goniometers. J Orthop Sci. 23(3): 504-510,
2018.
20180265
Matsuba T, Hata Y, Ishigaki N, Nakamura K,
Kato H : Osteoarthritis progression of the shoulder : A longterm follow-up after mini-open rotator cuff repair. J Orthop
Surg (Hong Kong) 26(2): 2309499018768100, 2018.
20180266
I k e g a m i S , Ta k a h a s h i J , M i s a w a H ,Tsutsumimoto T, Yui M, Kuraishi S, Futatsugi T, Uehara M,
Oba H, Kato H : Spinal Cord MRI Signal Changes at One
Year after Cervical Decompression Surgery is Useful for
Predicting Mid-term Clinical Outcome: An Observational
Study Using Propensity Scores. Spine J. 18(5): 755-761,
2018.
20180267
Uehara M, Takahashi J, Akazawa Y, Kuraishi
S, Ikegami S, Futatsugi T, Oba H, Kato H : Posterior spinal
fusion for scoliosis after Fontan procedure: a case series andreview of the literature. J Orthop Sci. 23(2): 294-298, 2018.
20180268
Uehara M, Takahashi J, Ikegami S, Kuraishi S,
Futatsugi T, Oba H, Koseki M, Kato H : Mid-Term Resultsof Computer-Assisted Skip Pedicle Screw Fixation for
Patients with Lenke Type 1 and 2 Adolescent Idiopathic
Scoliosis: A Minimum Five-Year Follow-Up Study. J Orthop
Sci. 23(2): 248-252, 2018.
20180269
Uehara M, Takahashi J, Ikegami S, Kuraishi S,
Fukui D, Imamura H, Okada K, Kato H : Thoracic aortic
aneurysm is an independent factor associated with diffuse
idiopathic skeletal hyperostosis. Bone Joint J. 100-B(5):617-621, 2018.
20180270
Uehara M, Nakamura Y, Takahashi J, Isobe
F, Ikegami S, Suzuki T, Uchiyama S, Kamimura M, Kato
H : Efficacy of teriparatide and denosumab combination
treatment in a patient with atypical femoral fracture andBehçet’s disease: a case report and review of the literature.
Mod Rheumatol Case Rep. 2(1): 92-96, 2018.
20180271
Mimura T, Takahashi J, Ikegami S, Kuraishi S,
Shimizu M, Futatsugi T, Uehara M, Oba H, Koseki M, Kato
H : Can surgery for adolescent idiopathic scoliosis of lessthan 50 degrees of main thoracic curve achieve good results?
J Orthop Sci. 23(1): 14-19, 2018.
20180272

Uehara M, Nakamura Y, Takahashi J, Suzuki T,

Kato H : Efficacy of denosumab in two cases with multiple
system atrophy and osteoporosis. Ther Clin Risk Manag. 14:
817-822, 2018.
20180273
Oba H, Ebata S, Takahashi J, Koyama K,
Uehara M, Kato H, Haro H, Ohba T : Pedicle Perforation
while Inserting Screws using O-arm Navigation during
Surgery for Adolescent Idiopathic Scoliosis: Risk Factors
and Effect of Insertion Order. Spine (Phila Pa 1976). 43(24):
E1463-E1468, 2018.
20180274
U e h a r a M , N a k a m u r a Y, Ta k a h a s h i J ,Kamimura M, Isobe F, Yamaguchi T, Kosho T, Uchiyama
S, Suzuki T, Kato H : Efficacy of denosumab therapy forneurofibromatosis type 1 with osteoporosis and history of
fractures: a case report. Ther Clin Risk Manag. 14: 12431246, 2018.
20180275
Uehara M, Kosho T, Yamamoto N, Takahashi
H, Shimakura T, Nakayama J, Kato H, Takahashi J : Spinal
manifestations in 12 patients with musculocontractural
Ehlers-Danlos syndrome caused by CHST14/D4ST1
deficiency (mcEDS-CHST14). Am J Med Genet A. 176(11):2331-2341, 2018.
20180276
Komatsu M, Uchiyama S, Kimura T, Suenaga
N, Hayashi M, Kato H : Recurrent Cubital Tunnel Syndrome
Caused by Ganglion: A Report of Nine Cases. J Hand Surg
Asian Pac Vol. 23(2): 210-216, 2018.
20180277
Kito M, Matsumoto S, Ae K, Tanizawa T,
Gokita T, Hayakawa K, Funauchi Y, Yamamoto N : Giantcell tumor of the distal femur: Outcome beyond 20 years offollow-up after curettage with polymethylmethacrylate. J
Orthop Sci. 23(6): 1051-1055, 2018.
20180278
Okamoto M, Kito M, Yoshimura Y, Aoki K,
Suzuki S, Tanaka A, Takazawa A, Yoshida K, Kato H : The
status quo of treatment and clinical outcomes for patientsover 80 years of age with high-grade soft tissue sarcoma:
report from the soft tissue tumor registry in Japan. Jpn J Clin
Oncol. 48(10): 900-905, 2018.
20180279
Kuroda, C. Ueda, K. Haniu, H. Ishida, H.
Okano, S. Takizawa, T. Sobajima, A. Kamanaka, T. Yoshida,
K. Okamoto, M. Tsukahara, T. Matsuda, Y. Aoki, K. Kato,
H. Saito, N : Different aggregation and shape characteristics
of carbon materials affect biological responses in RAW264
cells. Int J Nanomedicine. 13: 6079-6088, 2018.
20180280
Yamazaki H, Miyaoka S, Kato H : Attritionof the Extensor Tendon of the Index Finger Following an
Avulsion Fracture of the Third Metacarpal. J Hand Surg

20

Asian Pac. 23(1): 144-148, 2018.
20180281
Yamazaki H, Sakurai T, Uchiyama S, Kato,
H : Reliability and Concurrent Validity of the Ring Gauge
Method and the Metacarpal Head Tape Measure Method of
Measuring Hand Size. J Hand Surg Asian Pac. 23(3): 382387, 2018.
20180282
Shimodaira H, Tensho K, Akaoka Y, Koyama S,
Maruyama M, Kato H, Saito N : The acetabular fossa may
not be located at the true center of the acetabulum: a detailed
analysis using preoperative CT images. J Bone Joint Surg
Am. 100(5): e27, 2018.
20180283
Tensho K, Shimodaira H, Akaoka Y, Koyama
S, Hatanaka D, Ikegami S, Kato H, Saito N : Lateralizationof the tibial tubercle in recurrent patellar dislocation:verification using multiple evaluative methods for the tibial
tubercle. J Bone Joint Surg Am. 100(9): e58, 2018.
20180284
Koyama S, Tensho K, Shimodaira H, Iwaasa T,
Horiuch H, Kato H, Saito N : A case of prefemoral fat pad
impingement syndrome caused by hyperplastic fat pad. Case
Reports in Orthopedics. 2018: 3583049, 2018.
20180285
Suzuki T, Nakamura Y, Tanaka M, Kamimura
M, Ikegami S, Uchiyama S, Kato H : Comparison of theeffects of denosumab with either active vitamin D or native
vitamin D on bone mineral density and bone turnovermarkers in postmenopausal osteoporosis. Mod Rheumatol.
28(2): 376-379, 2018.
20180286
Suzuki T, Nakamura Y, Kato H : Significant
improvement of bone mineral density by denosumab withoutbisphosphonate pre-treatment in glucocorticoid-induced
osteoporosis. Mod Rheumatol. 28(5): 885-889, 2018.
20180287
Isobe F, Nakamura Y, Suzuki T, Kato H : Effects
of denosumab on osteoporosis in three cases with anorexia
nervosa and a review of the literature. Mod Rheumatol Case
Rep. 2(2): 104-106, 2018.
20180288
Nakamura Y, Suzuki T, Yamazaki H, Kato H :Tofacitinib Versus Non-Tumor Necrosis Factor Biologics forPatients With Active Rheumatoid Arthritis. Arch Rheumatol.
33(2): 154-159, 2018.
20180289
Suzuki T, Nakamura Y, Kato H : Effects ofdenosumab on bone metabolism and bone mineral densitywith anti-TNF inhibitors, tocilizumab, or abatacept inosteoporosis with rheumatoid arthritis. Ther Clin Risk
Manag. 14: 453-459, 2018.

20180290
Nakamura Y, Kamimura M, Morikawa A,
Taguchi A, Suzuki T, Kato H : Significant improvement ofbone mineral density by denosumab treatment in Japaneseosteoporotic patients following breast cancer treatment. Ther
Clin Risk Manag. 14: 543-549, 2018.
20180291
Suzuki T, Nakamura Y, Kato H : Vitamin D andcalcium addition during denosumab therapy over a periodof four years significantly improves lumbar bone mineraldensity in Japanese osteoporosis patients. Nutrients. 10(3):E272, 2018.
20180292
Kumaki D, Nakamura Y, Suzuki T, Kato H :Efficacy of Denosumab for Osteoporosis in Two Patientswith Adult-Onset Still’s Disease—Denosumab Efficacy in
Osteoporotic Still’s Disease Patients. J Clin Med. 7(4): E63,
2018.
20180293
Ohnishi T, Hida M, Nakamura Y, Wada C: Novel method for evaluation of hindfoot alignment inweight-bearing position using laser beam. J Phys Ther Sci.
30(3): 474-478, 2018.
20180294
Suzuki T, Nakamura Y, Kamimura M, Kato
H : Denosumab significantly improves lumbar spine bonemineral density more in treatment-naïve than in long-termbisphosphonate-treated patients. Bone Rep. 8: 110-114,
2018.
20180295
Kamimura M, Taguchi A, Nakamura Y, Koiwai
H, Ikegami S, Uchiyama S, Kato H : Pretreatment of daily
teriparatide enhances the increase of bone mineral density
in cortical bones by denosumab therapy. Ther Clin Risk
Manag. 14: 637-642, 2018.
20180296
Nakamura Y, Kamimura M, Koiwai H, Kato H :Adequate nutrition status important for bone mineral density
improvement in a patient with anorexia nervosa. Ther Clin
Risk Manag. 14: 945-948, 2018.
20180297
Kumaki D, Nakamura Y, Sakai N, Kosho T,
Nakamura A, Hirabayashi S, Suzuki1 T, Kamimura M, Kato
H : Efficacy of Denosumab for Glucocorticoid-Induced
Osteoporosis in an Adolescent Patient with Duchenne
Muscular Dystrophy. A Case Report. JBJS Case Connect.
8(2): e22, 2018.
20180298
Suzuki T, Nakamura Y, Kato H : Determinationof serum bone-related minerals during denosumab treatmentin osteoporosis patients with rheumatoid arthritis. Clin Nutr
ESPEN. 26: 53-56, 2018.
20180299

Suzuki T, Nakamura Y, Kato H : Efficacy,

21

safety, and compliance of ibandronate treatment for 3
years in postmenopausal Japanese women with primaryosteoporosis. Osteoporosis and Sarcopenia. 4(2): 69-72,
2018.
20180300
Suzuki T, Nakamura Y, Kato H : Efficacyof 4-year denosumab treatment alone or in combination
with teriparatide in Japanese postmenopausal osteoporotic
women. Mod Rheumatol. 9(4): 676-681, 2018.
20180301
Murakami K, Kikugawa S, Kobayashi Y,
Uehara S, Suzuki T, Kato H, Udagawa N, Nakamura Y :Olfactomedin-like protein OLFML1 inhibits Hippo signaling
and mineralization in osteoblasts. Biochem Biophys Res
Commun. 505(2): 419-425, 2018.
20180302
Noguchi O, Nakamura Y, Kato H : Suppressionof Methotrexate-Induced Elevations in the Serum Alanine
Aminotransferase Level of Patients with Rheumatoid
Arthritis Who Had Prior Hepatitis B Infection. Health. 10(5):531-541, 2018.
20180303K o b a y a s h i T, N a k a m u r a Y, S u z u k i T,
Yamaguchi T, Takeda R, Takagi M, Hasegawa T, Kosho T,
Kato K : Efficacy and Safety of Denosumab Therapy for
Osteogenesis Imperfecta Patients with Osteoporosis—Case
Series. J Clin Med. 7(12): E479, 2018.
20180304
Suzuki T, Nakamura Y, Kato H : Calcium
and vitamin D supplementation with 3-year denosumab
treatment is beneficial to enhance bone mineral density inpostmenopausal patients with osteoporosis and rheumatoid
arthritis. Ther Clin Risk Manag. 15: 15-22, 2018.
20180305
Oshibs H, Itsubo T, Komatsu M, Uchiyama S,
Kato H : Bone peg grafting for capitellar osteochondritis
dissecans in adolescent baseball players. JBJS Essent Surg
Tech. 8(1): e8, 2018.

Neurosurgery
20180308
Fujii Y, Muragaki Y, Kawamata T : Letter to the
Editor. Resection for WHO Grade III gliomas Response. J
Neurosurge 129: 250-251, 2018.
20180309
Fujii Y, Muragaki Y, Maruyama T, Nitta M,
Saito T, Ikuta S, Iseki H, Hongo K, Kawamata T : Thresholdof the extent of resection for WHO grade III gliomas:
retrospective volumetric analysis of 122 cases using
intraoperative MR imaging. . J Neurosurge 129: 1-9, 2018.
20180310
Goto T, Hongo K, Ogiwara T, Nagm A,
Okamoto J, Muragaki Y, Lawton M, McDermott M, Berger
M : Intelligent Surgeon's Arm Supporting System iArmS in
Microscopic Neurosurgery Utilizing Robotic Technology.
World Neurosurg. 119: e661-e665, 2018.
20180311
Goto T, Ndubuisi C, Kobayashi T, Kiuchi T,
Kodama K, Sakai K, Hongo K : The Usefulness of NearInfrared Spectroscopy in Monitoring the Location of
Eloquent Area and Function Preservation in Brain Surgery.
International Neuroscience Journal 2: 1-7, 2018.
20180312
Hanaoka Y, Koyama J, Kiuchi T, Kamiya K,
Kuwabara H, Kamijo T, Horiuchi T, Hongo K : Proximal
balloon protection during carotid artery stenting via thetransradial approach. Journal of Neuroendovascular Therapy
12: 520-526, 2018.
20180313
Hanaoka Y, Koyama J, Nagm A, Kamiya K,
Chiba A, Kamijo T, Ogiwara T, Horiuchi T, Hongo K :Transradial stenting with a 6Fr modified Simmonds guiding
sheath for stenosis of the common carotid artery. Journal of
Neuroendovascular Therapy 12: 573-579, 2018.

20180306
Tsuyoshi Toyota, Hiroshi Horiuchi, Yoshiyuki
N a k a m u r a , I k u y a Ya m a z a k i , Ts u t o m u Ta k i z a w a :Disassembly of the inner head of a bipolar hip prosthesis.
Arthroplasty Today. 4(3): 266-269, 2018.

20180314
Hanaoka Y, Koyama J, Nagm A, Uchiyama
T, Kiuchi T, Kamiya K, Kamijo T, Ogiwara T, Horiuchi
T, Hongo K : Transradial neuroendovascular treatment foranterior circulation lesions: An initial experience with a 6 Fr
guiding sheath. Journal of Neuroendovascular Therapy 12:532-541, 2018.

20180307
Yoshimura Y, Ikegami S, Aoki K, Isobe K,
Kito M, Kawasaki K, Ishimine N, Kurata J, Sugano M,
Kato H : Incidence, Diagnosis, and Risk Factors of Venous
Thromboembolism after Surgery for Malignant Bone andSoft Tissue Tumor of Lower Extremity. Int J Phys Med
Rehabil. 6: 448, 2018.

20180315
Hanaoka Y, Ogiwara T, Kakizawa Y, Nagm
A, Seguchi T, Aoyama T, Koyama JI, Sato A, Hongo
K : Calcified ectopic TSH-secreting pituitary adenoma
mimicking craniopharyngioma: a rare case report andliterature review. Acta Neurochir (Wien). 160: 2001-2005,2018.
20180316
Hasegawa T, Ogiwara T, Nagm A, Goto T,
Aoyama T, Hongo K: : Risks of endoscopic temporal

22

ventriculocisternostomy for isolated lateral ventricle:
Anatomical surgical nuances. World Neurosurg. 110: 189192, 2018.

20180326
Ogiwara T, Nagm A, Hongo K : Letter tothe Editor. Posterior pseudocapsule in macroadenomas. J
Neurosurg. 129: 562-563, 2018.

20180317
Hasegawa T, Ogiwara T, Nagm A, Goto T,
Horiuchi T, Hongo K: : Cystic lymphocytic hypophysitis
mimicking pituitary apoplexy: A daunting challenge. World
Neurosurg. 118: 1-4, 2018.

Dentistry & Oral Surgery

20180318
Horiuchi T, Ichinose S, Agata M, Ito K, Hongo
K : STA-ACA bypass using the ipsilateral free STA graft as
an interposition graft and A3-A3 anastomosis for treatmentof bilateral ACA steno-occlusive ischemia. Acta Neurochir(Wien). 160: 779-782, 2018.
20180319
Horiuchi T, Kiuchi T, Koyama J, Hanaoka Y, Ito
K, Hongo K: : Wrap-clipping as rescue surgical techniquefor vessel perforation due to stent strut: a technical note.
Acta Neurochir (Wien) 160: 1955-1959, 2018.
20180320
Horiuchi T, Miyaoka Y, Hasegawa T, Ito K,
Hongo K : Usefulness of venous catheter as an intraluminal
stent for end-to-end venous anastomosis. Acta Neurochir(Wien). 160: 1139-1141, 2018.
20180321
Kuroiwa M, Yako T, Goto T, Higuchi K,
Kitazawa K, Horiuchi T, Kobayashi S : Inter-capsularresection of cervical vagus nerve schwannoma. J Clin
Neurosci. 54: 161-164, 2018.
20180322
Nagm A, Horiuchi T, Hongo K : Letter tothe Editor Regarding Minimally Invasive Approaches forAnterior Skull Base Meningiomas: Supraorbital Eyebrow,
Endoscopic Endonasal, or Combination of Both? Anatomic
Study, Limitations, and Surgical Application. World
Neurosurg. 116: 474-474, 2018.
20180323
Nagm A, Ogiwara T, Goto T, Hongo K, Ohata K: Letter to the Editor. Collecting data about the transorbital
endoscopic eyelid approach. J Neurosurg. 129: 275-276,
2018.
20180324
Nagm A, Goto T, Ogiwara T, Horiuchi T,
Hongo K : Endoscopic transpalpebral transorbital anterior
petrosectomy: does Bsafer surgical freedoms necessitates
modifications? Acta Neurochir (Wien). 160: 1583-1584,2018.
20180325
Ogiwara T, Goto T, Hara Y, Hongo K : RealTime Navigation-Guided Drilling Technique for Skull Base
Surgery in the Middle and Posterior Fossae. J Neurol Surg B
Skull Base. 79(Suppl 4): S334-S339, 2018.

20180327
Chen W, Shimane T, Kawano S, Alshaikh A,
Kim SY, Chung SH, Kim RH, Shin KH, Walentin K, Park
NH, Schmidt-Ott KM, Kang MK : Human Papillomavirus
16 E6 Induces FoxM1B in Oral Keratinocytes through
GRHL2. J Dent Res 97: 795-802, 2018.
20180328
Hasegawa T, Yanamoto S, Otsuru M, Kakei
Y, Okura M, Yamakawa N, Yamada SI, Ota Y, Umeda
M, Kirita T, Kurita H, Ueda M, Komori T; Japan Oral
Oncology Group (JOOG) : Multi-center retrospective studyof the prognosis and treatment outcomes of Japanese oral
squamous cell carcinoma patients with single lymph nodemetastasis and extra nodal extension. J Surg Oncol 117:
1736-1743, 2018.
20180329
Yamada S, Otsuru M, Yanamoto S, Hasegawa T,
Aizawa H, Kamata T, Yamakawa N, Kohgo T, Ito A, Noda Y,
Hirai C, Kitamura T, Okura M, Kirita T, Ueda M, Yamashita
T, Ota Y, Komori T, Umeda M, Kurita H : Progression levelof extracapsular spread and tumor budding for cervicallymph node metastasis of OSCC. Clin Oral Investig 22:1311-1318, 2018.
20180330
Hasegawa T, Yamada SI, Ueda N, Soutome S,
Funahara M, Akashi M, Furuno S, Miyamoto H, Hayashida
S, Amano R, Mori K, Kojima Y, Kurita H, Kirita T, Umeda
M, Shibuya Y, Fujita S, Komori T; Japanese Study Group of
Cooperative Dentistry with Medicine (JCDM) : Treatment
modalities and risk factors associated with refractory
neurosensory disturbances of the inferior alveolar nerve
following oral surgery: a multicentre retrospective study. Int
J Oral Maxillofac Surg. 47: 794-801, 2018.
20180331
Rokutanda S, Yamada S, Yanamoto S, Omori K,
Fujimura Y, Morita Y, Rokutanda H, Kohara H, Fujishita A,
Nakamura T, Yoshimi T, Yoshida N, Umeda M : Comparisonof osseous healing after sagittal split ramus osteotomy andintraoral vertical ramus osteotomy. Int J Oral Maxillofac
Surg. 47: 1316-1321, 2018.
20180332
Yamada S, Kurita H, Kamata T, Kirita T, Ueda
M, Yamashita T, Ota Y, Otsuru M, Yamakawa N, Okura
M, Aikawa T, Umeda M : Significant prognostic factors
affecting treatment outcomes of salivary gland carcinoma: amulticenter retrospective analysis. Odontology 106: 96-102,
2018.

23

20180333
Tanaka H, Yamada S, Aizawa H, Hayashi
K, Shimane T, Karasawa I, Yoshimura N, Nishimaki
F, Arakawa Y, Kurita H : Mechanical Properties andHistological Evaluation of Bone Grafting Materials
Containing Different Ratios of Calcium Phosphate Cement
and Porous β-tricalcium Phosphate Granules. 信州医学雑誌
66: 139-150, 2018.
20180334
Nakanishi Y, Yamada S, Nishizawa R, Shimane
T, Kamata T, Koike T, Uehara S, Kurita H : Risk factors insecuring successful surgical resection of oral squamous cell
carcinoma. Oral Science International. 15: 56-60, 2018.
20180335
Outa R, Yamada S, Nrase T, Yshimura H,
Sakurai A, Ishii S, Tomioka T, Sano K, Umeda M. Shibahara
T, Kurita H : Treatment outcomes after articular eminectomy
in patients with long-standing/habitual temporomandibular
joint dislocation. J Oral Maxillofac Surg Med Pathol 30:
238-240, 2018.

bladder after spinal cord injury. World J Urol 36(10): 15691576, 2018.
20180341
Minagawa T, Fukui D, Shingu K, Ogawa T,
Okada K, Ishizuka O : Intraoperative detection of inferior
vena caval tumor thrombus extending from metastatic lymph
node of renal cell carcinoma using ultrasonography. J Med
Ultrason 45(2): 367-370, 2018.

Ophthalmology
20180342
Terasaki H, Ogura Y, Kitano S, Sakamoto T,
Murata T, Hirakata A, Ishibashi T : Management of diabetic
macular edema in Japan: a review and expert opinion. Jpn J
Ophthalmol 62: 1-23, 2018.
20180343
Kakihara S, Hirano T, Iesato Y, Imai A,
Toriyama Y, Murata T : Extended field imaging using sweptsource optical coherence tomography angiography in retinal
vein occlusion. Jpn J Ophthalmol 62: 274-279, 2018.

Urology
20180336
Imamura T, Shimamura M, Ogawa T, Minagawa
T, Nagai T, Gautam SS, Ishizuka O : Biofabricated structures
reconstruct functional urinary bladders in radiation-injured
rat bladders. Tissue Eng Part A 24: 1574-1587, 2018.
20180337
Masaki K, Sakai M, Kuroki S, Jo JI, Hoshina
K, Fujimori Y, Oka K, Amano T, Yamanaka T, Tachibana M,
Tabata Y, Shiozawa T, Ishizuka O, Hochi S, Takashima S :FGF2 has distinct molecular functions from GDNF in themouse germline niche. Stem cell reports 10(6): 1782-1792,2018.
20180338
Minagawa T, Gotoh M, Yokoyama O, Sugaya
K, Yamanishi T, Kawahara K, Kaga K, Kikuchi T, Nishizawa
O; FRESH study group : Therapeutic effect of propiverinehydrochloride on mixed-type urinary incontinencein women: The Female Urgency and Stress Urinary
Incontinence Study of Propiverine Hydrochloride trial. Int J
Urol 25(5): 486-491, 2018.

20180344
Takamura Y, Ohkoshi K, Murata T : New
Strategies for Treatment of Diabetic Macular Edema. J
Ophthalmol 2018: 4292154, 2018.
20180345
Hirano T, Kakihara S, Toriyama Y, Nittala MG,
Murata T, Sadda S : Wide-field en face swept-source opticalcoherence tomography angiography using extended fieldimaging in diabetic retinopathy. Br J Ophthalmol 102: 11991203, 2018.
20180346
Hirano T, Toriyama Y, Iesato Y, Imai A, Murata
T : Changes in plasma vascular endothelial growth factor
level after intravitreal injection of ranibizumab, aflibercept,
or bevacizumab for diabetic macular edema. Retina 38:
1801-1808, 2018.
20180347
Hirano T, Imai A, Kasamatsu H, Kakihara S,
Toriyama Y, Murata T : Assessment of diabetic retinopathy
using two ultra-wide-field fundus imaging systems, theClarus® and Optos™ systems. BMC Ophthalmol 1: 332,
2018.

20180339
O g a w a T, I s h i z u k a O , U e d a T, Ty a g i
P, Chancellor MB, Yoshimura N : Pharmacologicalmanagement of interstitial cystitis /bladder pain syndrome
and the role cyclosporine and other immunomodulating
drugs play. Expert Rev Clin Pharmacol 11(5): 495-505,
2018.

20180348
Hirano T, Chanwimol K, Weichsel J, Tepelus
T, Sadda S : Distinct Retinal Capillary Plexuses in Normal
Eyes as Observed in Optical Coherence Tomography
Angiography Axial Profile Analysis. Sci Rep 8(1): 9380,
2018.

20180340
Wyndaele JJ, Birch B, Borau A, Burks F,
Castro-Diaz D, Chartier-Kastler E, Drake M, Ishizuka O,
Minagawa T, Opisso E, Peters K, Padilla-Fernández B,
Reus C, Sekido N : Surgical management of the neurogenic

20180349
Iesato Y, Tanaka M, Murata M, Kitahara J,
Hirano T, Kurenuma T, Yoshida N, Murata T : Complete
regression of branching vascular network in polypoidal
choroidal vasculopathy by ranibizumab and photodynamic

24

therapy, two case reports. BMC Ophthalmol. 18: 284, 2018.
20180350
Takamura Y, Shimura M, Katome T, Someya H,
Sugimoto M, Hirano T, Sakamoto T, Gozawa M, Matsumura
T, Inatani M; writing committee of Japan-Clinical Retina
Research Team (J-CREST). : Effect of intravitreal
triamcinolone acetonide injection at the end of vitrectomy
for vitreous haemorrhage related to proliferative diabetic
retinopathy. Br J Ophthalmol. 102: 1351-1357, 2018.
20180351
Kurokawa T, Hamano H, Muraki T, Uehara
T, Masuo S, Murata T : Immunoglobulin G4-related
dacyroadenitis presenting as bilateral chorioretinal folds
from severely enlarged lacrimal glands. Am J Ophthalmol
Case Rep. 9: 88-92, 2018.

Otorhinolaryngology
20180352
Takahashi M, Arai Y, Sakuma N, Yabuki K,
Sano D, Nishimura G, Oridate N, Usami SI : Cochlear
volume as a predictive factor for residual-hearing
preservation after conventional cochlear implantation. Acta
otolaryngol. 138(4): 345-350, 2018.
20180353
Ikezono T, Matsumura T, Matsuda H, Shikaze
S, Saitoh S, Shindo S, Hasegawa S, Oh SH, Hagiwara Y,
Ogawa Y, sato H, Tono T, Araki R, maeda Y, Usami SI, Kase
Y : The diagnostic performance of a novel ELISA for human
CTP (Cochlin-tomoprotein) to detect perilymph leakage.
PLoS One 13(1): e0191498, 2018.
20180354
Moteki H, Isaka Y, Inaba Y, Motobayashi M,
Nishio SY, Ohira S, Yano T, Iwasaki S, Shiozawa T, Koike
K, Usami SI : A rational approach to identifying newborns
with hearing loss caused by congenital cytomegalovirus
infection by dried blood spot screening. Acta otolaryngol.
138(8): 708-712, 2018.
20180355
Kobayashi M, Miyagawa M, Nishio SY, Moteki
H, Fujikawa T, Ohyama K, Sakaguchi H, Miyanohara I,
Sugaya A, Naito Y, Morita SY, Kanda Y, Takahashi M,
Ishikawa K, Nagano Y, Tono T, Oshikawa C, Kihara C,
Takahashi H, Noguchi Y, Usami SI : WFS1 mutation
screening in a large series of Japanese hearing loss patients:
Massively parallel DNA sequencing-based analysis. PLoS
One 13(3): e0193359, 2018.
20180356
Nishio SY, Moteki H, Usami SI : Simple andefficient germline copy number variant visualization method
for the Ion AmpliSeq™ custom panel. Mol Genet Genomic
Med. 6(4): 678-686, 2018.
20180357

Moteki H, Fujinaga Y, Goto T, Usami SI :Pneumolabyrinth, intracochlear and vestibular fluid loss
after cochlear implantation. Auris Nasus Larynx. 45: 11161120, 2018.
20180358
N a k a t a n i T, U e d a S , N i s h i o S I , U s a m i
SI : Introgressive Hybridization of the Erebia ligea
Complex(Lepidoptera, Nymphalidae) in the Far Eastern
Region. Butterfly Science 11: 26-37, 2018.
20180359
Abe S, Takeda H, Nishio SY, Usami SI :Sensorineural hearing loss and mild cardiac phenotype
caused by an EYA4 mutation. Human Genome Variation
5(23): 1-4, 2018.
20180360
Nakatani T, Ueda S, Nishio SY, Usami SI :Molecular Phylogeny of the Genus Erebia(Lepidoptera,
Nymphalidae, Satyrinae) : Species Groups Inferred from
Mitochondrial and Nucleus Gene Sequences. Butterfly
Science 12: 27-48, 2018.
20180361
Abe S, Nishio SY, Yokota Y, Moteki H,
Kumakawa K, Usami SI : Diagnostic pitfalls for GJB2related hearing loss: A novel deletion detected by ArrayCGH analysis in a Japanese patient with congenital profoundhearing loss. Cin Case Rep. 6: 2111-2116, 2018.
20180362
Iwasa YI, Tsukada K, Kobayashi M, Kitano
T, Mori K, Yoshimura H, Fukuoka H, Usami SI : Bilateraldelayed endolymphatic hydrops evaluated by bilateral
intratympanic injection of gadodiamide with 3T-MRI. PLoS
One 13(12): e0206891, 2018.

Obstetrics and Gynecology
20180363
Miyamoto T, Ando H, Asaka R, Yamada
Y, Shiozawa T : Mutation analysis by whole exome
sequencing of endometrial hyperplasia and carcinoma in
one patient: Abnormalities of polymerase epsilon and thephosphatidylinositol-3 kinase pathway. J Obstet Gynaecol
Res. 44(1): 179-183, 2018.
20180364
Masaki Kaito, Sakai Mizuki, Kuroki Shunsuke,
Jo Jun-Ichiro, Hoshina Kazuo, Fujimori Yuki, Oka Kenji,
Amano Toshiyasu, Yamanaka Takahiro, Tachibana Makoto,
Tabata Yasuhiko, Shiozawa Tanri, Ishizuka Osamu, Hochi
Shinichi, Takashima Seiji, : FGF2 Has Distinct MolecularFunctions from GDNF in the Mouse Germline Niche. Stem
Cell Repor ts 10: 1782-1792, 2018.
20180365
Sekiguchi M, Miyoshi Y, Kikuchi N, Sago H :Pregnancy outcomes in female childhood cancer survivors:
Nationwide survey in Japan. Pediatr Int. 60: 254-258, 2018.

25

20180366
C hi t aru Tokut ake, A kiko H aga , K e s a m i
Sakaguchi, Atsuko Samejima, Miki Yoneyama, Yoshiharu
Yokokawa, Masayoshi Ohira, Motoki Ichikawa and Makoto
Kanai : Infant Suffocation Incidents Related to Co-Sleepingor Breastfeeding in the Side-Lying Position in Japan. J. Exp.
Med. 246: 121-130, 2018.
20180367
Ayako Tateishi, Satoshi Ohira, Yoichiro
Yamamoto, Hiroyuki Kanno : Histopathological findings ofpregnancy-induced hypertension: histopathology of earlyonset type reflects two-stage disorder theory. Virchows Arch472: 635-642, 2018.
20180368
Hideaki Moteki, Yuichi Isaka, Yuji Inaba,
Mitsuo Motobayashi, Shin-Ya Nishio, Satoshi Ohira,Takuya Yano, Satoshi Iwasaki, Tanri Shiozawa, Kenichi
Koike, Shin-Ichi Usami : A rational approach to identifying
ne w bor ns w i t h heari ng l os s caus ed by c o n g e n ita lcytomegalovirus infection by dried blood spot screening.
Acta Otolaryngol 138: 708-712, 2018.
20180369
Yen TT, Miyamoto T, Asaka S, Chui MH,
Wang Y, Lin SF, Stone RL, Fader AN, Asaka R, Kashima H,
Shiozawa T, Wang TL, Shih IM, Tanner EJ 3rd. : Loss of
ARID1A expression in endometrial samplings is associatedwith the risk of endometrial carcinoma. . Gynecol Oncol.
150(3): 426-431, 2018.

Anesthesiology and Resuscitology
20180370
Yo s h i t a n i K , M a s u i K , K a w a g u c h i M ,Kawamata M, Kakinohana M, Kato S, Hasuwa K, Yamakage
M, Yoshikawa Y, Nishiwaki K, Aoyama T, Inagaki Y,
Yamasaki K, Matsumoto M, Ishida K, Yamashita A, Seo
K, Kakumoto S, Hayashi H, Tanaka Y, Tanaka S, IshidaT, Uchino H, Kakinuma T, Yamada Y, Mori Y, Izumi S,
Nishimura K, Nakai M, Ohnishi Y : Clinical Utility of
Intraoperative Motor-Evoked Potential Monitoring toPrevent Postoperative Spinal Cord Injury in Thoracic andThoracoabdominal Aneurysm Repair: An Audit of theJapanese Association of Spinal Cord Protection in Aortic
Surgery Database. Anesthesia & Analgesia 126(3): 763-768,
2018.

TRPV2 chnnels in sensory neurons increases limb use andweight bearing but dose not affect spontaneous flinching
behavior in a mouse model of bone cancer. Molecular Pain
14: 1-11, 2018.
20180373
Sugiyama Y, Iida H, Amaya F, Matsuo K,
Matsuoka Y, Kojima K, Matsuno F, Hamaguchi T, Iseki M,
Yamaguchi K, Takahashi Y, Hara A, Sugasawa Y, Kawamata
M, Tanaka S, Inagaki Y, Otsuki A, Yamazaki M, Ito H :Prevalence of chronic postsurgical pain after thoracotomy
and total knee arthroplasty: a retrospective multicenter study
in Japan (Japanese Study Group of Subacute PostoperativePain). J Anesth 32: 434-438, 2018.
20180374
Sugiyama Y, Gotoh S, Urasawa M, Kawamata
M, Nakajima K : Hemodynamic response to massive
bleeding in a patient with congenital insensitivity to painwith anhidrosis. Case Reports in Anesthesiology 9593458:
1-4, 2018.
20180375
Sugiyama Y, Kiuchi C, Suzuki M, Maruyama
Y, Wakabayashi R, Ohno Y, Takahata S, Shibazaki T,
Kawamata M : Glucose management during insulinoma
resection using real-time subcutaneous continuous glucose
monitoring. Case Reports in Anesthesiology 6248467: 1-4,
2018.
20180376
Fuseya S, Ichino T, Tanaka S, Ishida K, Ishida
T, Kawamata M : Airway obstruction due to a laryngeal
polyp following insertion of a laryngeal mask airway. JA
Clin Rep 4: 43, 2018.
20180377
Ishida T, Tanaka S, Sakamoto A, Hirabayashi T,
Kawamata M : Plasma ropivacaine concentration after TAP
block in a patient with cardiac and renal failure. Local Reg
Anesth 11: 57-60, 2018.
20180378
Fuseya S, Ishida T, Ichino T, Kawamata M: Flattening of the Interventricular Septum during Onelung Ventilation in a Patient with Arrhythmogenic Right
Ventricular Cardiomyopathy . Shinshu Medical Journal 66:
443-449, 2018.

Plastic and Reconstructive Surgery
20180371
Sugiyama Y, Wakabayashi R, Urasawa M,
Maruyama Y, Shimizu S, Kawamata M : Contributed
equally: Perioperative characteristics of the accuracy of
subcutaneous continuous glucose monitoring - pilot study inneurosurgery and cardiac surgery - . Diabetes Technology
and Therapeutics 20(10): 654-661, 2018.
20180372
Yamamoto K, Tanaka S, Fuseya S, Ishida T,
Zhang H, Kawamata T, Kawamata M : Knockdown of

20180379
Nishioka H, Kondoh S, Yuzuriha S : Convex
bone deformity after closed reduction of nasal bone fracture.
J Plast Reconstr Aesthet Surg 71: 85-89, 2018.
20180380
Takashimizu I, Yuzuriha S : The amounts ofmelanin pigment causing color differences between thevermilion and lip mucosa. J Plast Reconstr Aesthet Surg 71:
1826-1827, 2018.

26

20180381
Yanagisawa D, Yuzuriha S : Stapling techniquethrough transparent dressing to fix skin grafts. Burns Open
2: 71-75, 2018.
20180382
Hosomi K, Nagai F, Yuzuriha S : Small-slice
thin-thickness skin harvesting in a net pattern for patientswith skin vulnerability. Burns Open 2: 79-84, 2018.
20180383
Suito M, Yuzuriha S, Iwasawa M, Yanagisawa
D, Kinjo Y, Takashimizu I, Hoshino Y : Therapeuticstrategies for elbow ankylosis due to heterotopic ossificationin patients with severe burns. JPRAS Open 17: 24-30, 2018.

Laboratory Medicine
20180384
Negishi T, Matsumoto T, Horiuchi K, Kasuga
E, Natori T, Matsuoka M, Ogiwara N, Sugano M, Uehara T,
Nagano N, Honda T : Characterization of clinically isolated
thymidine-dependent small-colony variants of Escherichia
coli producing extended-spectrum β-lactamase. J Med
Microbiol. 67: 33-39, 2018.
20180385
Nishikawa A, Ogiwara T, Nagm A, Sano K,
Okada M, Chiba A, Agata M, Kaneko T, Tamada H, Uehara
T, Hongo K : Atypical teratoid/rhabdoid tumor of the sellar
region in adult women: Is it a sex-related disease? J Clin
Neurosci. 49: 16-21, 2018.
20180386
Kinugawa Y, Uehara T, Matsuda K, Kobayashi
Y, Nakajima T, Hamano H, Kawa S, Higuchi K, Hosaka
N, Shiozawa S, Ishigame H, Nakamura T, Maruyama Y,
Nakazawa K, Nakaguro M, Sano K, Ota H : Promoter
hypomethylation of SKI in autoimmune pancreatitis. Pathol
Res Pract. 214: 492-497, 2018.
20180387
Taira C, Matsuda K, Takeichi N, Furukawa S,
Sugano M, Uehara T, Okumura N, Honda T : Rapid ABO
genotyping by high‐speed droplet allele‐specific PCR using
crude samples. J Clin Lab Anal. 32: e22196, 2018.
20180388
Kawakubo M, Horiuchi K, Matsumoto T,
Nakayama J, Akamatsu T, Katsuyama T, Ota H, Sagara J :Cholesterol-α-glucosyltransferase gene is present in most
Helicobacter species including gastric non-Helicobacter
pylori helicobacters obtained from Japanese patients.
Helicobacter. 23: e12449, 2018.
20180389
Yamazaki T, Joshita S, Kasuga E, Horiuchi
K, Sugiura A, Fujimori N, Komatsu M, Umemura T,
Matsumoto A, Tanaka E : A case of liver abscess co-infectedwith Desulfovibrio desulfuricans and Escherichia coli andreview of the literature. J Infect Chemother. 24: 393-397,
2018.

20180390
Notohara K, Kamisawa T, Uchida K, Zen Y,
Kawano M, Kasashima S, Sato Y, Shiokawa M, Uehara T,
Yoshifuji H, Hayashi H, Inoue K, Iwasaki K, Kawano H,
Matsubayashi H, Moritani Y, Murakawa K, Oka Y, Tateno
M, Okazaki K, Chiba T : Gastrointestinal manifestation of
immunoglobulin G4-related disease: clarification through amulticenter survey. J Gastroenterol. 53: 845-853, 2018.
20180391
M o c h i z u k i I , H o n d a T, H a n a o k a M :Pathogenetic Study from Fine Structure of the Capillary
Endothelial Cells in the Sarcoidosis Patients-Defects are
Observed in the Plasma Membrane, Lipid Droplets andPeripheral Nerve Fibers involving Hilological Consideration
for Phospholipase A2 (PLA2) and Stomatin-like Protein 2(SLP-2). J Infect Pulm Dis. 4: 135, 2018.
20180392
Nakajima N, Yoshizawa A, Nakajima T, Hirata
M, Furuhata A, Sumiyoshi S, Rokutan-Kurata M, Sonobe M,
Menju T, Miyamoto E, Chen-Yoshikawa TF, Date H, Haga
H : GATA6-positive lung adenocarcinomas are associatedwith invasive mucinous adenocarcinoma morphology,
hepatocyte nuclear factor 4α expression, and KRAS
mutations. Histopathology. 73: 38-48, 2018.
20180393
Nakajima T, Uehara T, Kobayashi Y, Kinugawa
Y, Yamanoi K, Maruyama Y, Suga T, Ota H : Leucinerich repeat-containing G-protein-coupled receptor 5
expression and clinicopathological features of colorectal
neuroendocrine neoplasms. Pathol Int. 68: 467-472, 2018.
20180394
Kurokawa T, Hamano H, Muraki T, Uehara
T, Masuo S, Murata T : Immunoglobulin G4-related
dacyroadenitis presenting as bilateral chorioretinal folds
from severely enlarged lacrimal glands. Am J Ophthalmol
Case Rep. 9: 88-92, 2018.
20180395
Miura K, Hamanaka K, Matsuoka S, Takeda
T, Agatsuma H, Hyogotani A, Ito K, Nishimaki F, Koizumi
T, Uehara T : Primary mediastinal dedifferentiatedliposarcoma: Five case reports and a review. Thorac Cancer.
9: 1733-1740, 2018.
20180396
Kurozumi M, Fujinaga Y, Kitou Y, Yamada A,
Ohya A, Adachi Y, Tsukahara Y, Nickel MD, Maruyama
K, Uehara T, Miyagawa S, Kadoya M : Evaluationof hemodynamic imaging findings of hypervascularhepatocellular carcinoma: comparison between dynamic
contrast-enhanced magnetic resonance imaging using radial
volumetric imaging breath-hold examination with k-spaceweighted image contrast reconstruction and dynamic
computed tomography during hepatic arteriography. Jpn JRadiol. 36: 295-302, 2018.

27

20180397
Yahikozawa H, Miyatake S, Sakai T, Uehara
T, Yamada M, Hanyu N, Futatsugi Y, Doi H, Koyano S,
Tanaka F, Suzuki A, Matsumoto N, Yoshida K : A Japanese
Family of Spinocerebellar Ataxia Type 21: Clinical and
Neuropathological Studies. Cerebellum. 17: 525-530, 2018.
20180398
Shimodaira T, Matsuda K, Uchibori T, Sugano
M, Uehara T, Honda T : Upregulation of osteopontin
expression via the interaction of macrophages andfibroblasts under IL-1b stimulation. Cytokine. 110: 63-69,2018.

20180405
Takeuchi Y, Seki T, Kobayashi N, Sano K,
Shigemura T, Shimojo H, Matsumoto K, Agematsu K :Analysis of serum IL-38 in juvenile-onset systemic lupus
erythematosus. Mod Rheumatol. 28: 1069-1072, 2018.
20180406
Makino T, Horiuchi A, Kajiyama M, Tanaka N,
Sano K, Maetani I : Delayed Bleeding Following Cold Snare
Polypectomy for Small Colorectal Polyps in Patients Taking
Antithrombotic Agents. J Clin Gastroenterol. 52: 502-507,
2018.

20180399
Komatsu M, Tanaka N, Kimura T, Fujimori
N, Sano K, Horiuchi A, Sugiura A, Yamazaki T, Shibata S,
Joshita S, Umemura T, Matsumoto A, Tanaka E : Miglitol
attenuates non-alcoholic steatohepatitis in diabetic patients.
Hepatol Res. 48: 1092-1098, 2018.

20180407
Muranaka F, Nakajima T, Iwaya M, Ishii K,
Higuchi K, Ogiwara N, Miyagawa S, Ota H : A Comparative
Immunohistochemical Study of Anal Canal Epithelium in
Humans and Swine, Focusing on the Anal Transitional Zone
Epithelium and the Anal Glands. Anat Rec. 301: 796-805,
2018.

20180400
Asaka S, Yoshizawa A, Saito K, Kobayashi Y,
Yamamoto H, Negishi T, Nakata R, Matsuda K, Yamaguchi
A, Honda T : Rapid point-of-care testing for epidermal
growth factor receptor gene mutations in patients withlung cancer using cell-free DNA from cytology specimen
supernatants. Int J Oncol. 52: 2110-2118, 2018.

20180408
Yen TT, Miyamoto T, Asaka S, Chui MH,
Wang Y, Lin SF, Stone RL, Fader AN, Asaka R, Kashima
H, Shiozawa T, Wang TL, Shih IM, Tanner EJ 3rd : Loss of
ARID1A expression in endometrial samplings is associatedwith the risk of endometrial carcinoma. Gynecol Oncol. 150:
426-431, 2018.

20180401
Asaka S, Yoshizawa A, Nakata R, Negishi T,
Yamamoto H, Shiina T, Shigeto S, Matsuda K, Kobayashi
Y, Honda T : Utility of bronchial lavage fluids for epithelial
growth factor receptor mutation assay in lung cancer
patients: Comparison between cell pellets, cell blocks andmatching tissue specimens. Oncol Lett. 15: 1469-1474,
2018.

20180409
Yamanoi K, Ishii K, Tsukamoto M, Asaka
S, Nakayama J : Gastric gland mucin-specific O-glycan
expression decreases as tumor cells progress from lobular
endocervical gland hyperplasia to cervical mucinous
carcinoma, gastric type. Virchows Arch. 473: 305-311, 2018.

20180402
Hirabayashi K, Yanagisawa R, Saito S, Higuchi
Y, Koya T, Sano K, Koido S, Okamoto M, Sugiyama
H, Nakazawa Y, Shimodaira S : Feasibility and Immune
Response of WT1 Peptide Vaccination in Combination with
OK-432 for Paediatric Solid Tumors. Anticancer Res. 38:
2227-2234, 2018.

20180410
Ohya A, Asaka S, Fujinaga Y, Kadoya M :Uterine cervical adenocarcinoma associated with lobular
endocervical glandular hyperplasia: Radiologic-pathologic
correlation. J Obstet Gynaecol Res. 44: 312-322, 2018.

20180403
Yanagisawa R, Koizumi T, Koya T, Sano K,
Koido S, Nagai K, Kobayashi M, Okamoto M, Sugiyama
H, Shimodaira S : WT1-pulsed Dendritic Cell Vaccine
Combined with Chemotherapy for Resected Pancreatic
Cancer in a Phase I Study. Anticancer Res. 38: 2217-2225,
2018.

20180411
Sugiura A, Joshita S, Umemura T, Yamazaki
T, Fujimori N, Kimura T, Matsumoto A, Igarashi K, Usami
Y, Wada S, Mori H, Shibata S, Yoshizawa K, Morita S,
Furuta K, Kamijo A, Iijima A, Kako S, Maruyama A,
Kobayashi M, Komatsu M, Matsumura M, MiyabayashiC,
Ichijo T, Takeuchi A, Koike Y, Gibo Y, Tsukadaira T, Inada
H, Kiyosawa K, Tanaka E : Past history of hepatocellular
carcinoma is an independent risk factor of treatment failurein patients with chronic hepatitis C virus infection receiving
direct-acting antivirals. J Viral Hepat. 25: 1462-1471, 2018.

20180404
Fujimori N, Umemura T, Kimura T, Tanaka
N, Sugiura A, Yamazaki T, Joshita S, Komatsu M, Usami
Y, Sano K, Igarashi K, Matsumoto A, Tanaka E : Serum
autotaxin levels are correlated with hepatic fibrosis andballooning in patients with non-alcoholic fatty liver disease.
World J Gastroenterol. 24: 1239-1249, 2018.

20180412
Joshita S, Umemura T, Usami Y, Yamashita Y,
Norman GL, Sugiura A, Yamazaki T, Fujimori N, Kimura T,
Matsumoto A, Igarashi K, Yoshizawa K, Ota M, Tanaka E :Serum Autotaxin Is a Useful Disease Progression Marker inPatients with Primary Biliary Cholangitis. Sci Rep. 8: 8159,
2018.

28

20180413
Yamazaki T, Joshita S, Umemura T, Usami Y,
Sugiura A, Fujimori N, Kimura T, Matsumoto A, Igarashi
K, Ota M, Tanaka E : Changes in serum evels of autotaxin
with direct-acting antiviral therapy in patients with chronic
hepatitis C. PLoS One. 13: e0195632, 2018.
20180414
Joshita S, Ichikawa Y, Umemura T, Usami Y,
Sugiura A, Shibata S, Yamazaki T, Fujimori N, Komatsu
M, Matsumoto A, Igarashi K, Ota M, Tanaka E : Serum
autotaxin is a useful liver fibrosis marker in patients withchronic hepatitis B virus infection. Hepatol Res. 48: 275285, 2018.
20180415
Kamijo T, Nagata K, Taira C, Higuchi Y, Arai S,
Okumura N : Fibrin monomers derived from thrombogenic
dysfibrinogenemia, Naples-type variant (BβAla68Thr),
showed almost entirely normal polymerization. Thromb Res.
172: 1-3, 2018.
20180416
Uchida M, Kaneko M, Hidaka Y, Yamamoto H,
Honda T, Takeuchi S, Saito M, Kawa S : High vaccination
coverage is associated with low epidemic level of seasonal
influenza in elementary schools: an observational study in
Matsumoto City, Japan. BMC Infect Dis. 18: 128, 2018.

combinedD-dimer with other indicators in suspected acuteaortic dissection patients. Int J Cardiol 267: 196, 2018.
20180422
Uehara M, Takahashi J, Ikegami S, Kuraishi S,
Fukui D, Imamura H, Okada K, Kato H : Thoracic aortic
aneurysm is an independent factor associated with diffuse
idiopathic skeletal hyperostosis. Bone Joint J 100-B: 617621, 2018.
20180423
Egi M, Kataoka J, Ito T, Nishida O, Yasuda
H, Okamaoto H, Shimoyama A, IzawaM, Matsumoto
S, Furushima N, Yamashita S, Takada K, Ohtsuka M,
Fujisaki N, Shime N, Inagaki N, Taira Y, Yatabe T, Nitta K,
Yokoyama T, Kushimoto S, Tokunaga K, Doi M, Masuda
T, Miki Y, Matsuda K, Asaga T, Hazama K, Matsuyama
H, Nishimura M, Mizobuchi S : Oxygen management inmechanically ventilated patients: A multicenter prospective
observational study. J Crit Care 46: 1-5, 2018.
20180424
Harada M, Motoki H, Kashima Y, Nakamura C,
Hashizume N, Kishida D, Imamura H, Kuwahara K : T-wave
alternans in a case with systemic lupus erythematosusrelated myocarditis. J Cardiol Cases 18: 119-122, 2018.

Comprehensive Cancer Therapy
20180417
F u j i m o t o K , Ya m a z a k i H , U e m a t s u A :Instability of nocturnal parasympathetic nerve function inpatients with chronic lung disease with or without nocturnal
desaturation. Int J Chron Obstruct Pulmon Dis. 13: 28412848, 2018.

Emergency and Critical Care Medicine
20180418
Imamura H, Kamijo H, Nitta K, Okada A :Nocturnal enuresis as the initial symptom of life-threatening
arrhythmia: a case report. BJGP 2(4): bjgpopen18X101624,2018.
20180419
Mochizuki K, Mori K, Nakamura Y, Uchimido
R, Kamijo H, Takeshige K, Nitta K, Imamura H : Earlychanges in the sequential organ failure assessmentscore among patients with sepsis-induced disseminatedintravascular coagulation. Clin Appl Thromb Hemost 24(9)Suppl.: 332S-339S, 2018.
20180420
Nitta K, Imamura H, Kashima Y, Kamijo H,
Ichikawa M, Okada M, Mochizuki K, Takayama H : Impactof a negative D-dimer result on the initial assessment of
acute aortic dissection. Int J Cardiol 258: 232-236, 2018.
20180421
Nitta K, Imamura H, Kashima Y, Kamijo
H, Ichikawa M, Okada M, Mochizuki K, Takeshige K :Response to letter from Jiang: The diagnostic value of20180425
Dufva O, Kankainen M, Kelkka T, Sekiguchi
N, Awad SA, Eldfors S, Yadav B, Kuusanmäki H, Malani D,
Andersson EI, Pietarinen P, Saikko L, Kovanen PE, Ojala
T, Lee DA, Loughran TP Jr., Nakazawa H, Suzumiya J,
Suzuki R, Ko YH, Kim WS, Chuang SS, Aittokallio T, Chan
WC, Ohshima K, Ishida F, Mustjoki S : Aggressive naturalkiller-cell leukemia mutational landscape and drug profilinghighlight JAK-STAT signaling as therapeutic target. Nat
Commun 9(1): 1567, 2018.
20180426
Fukushima T, Gomi D, Seno N, Gibo T,
Kobayashi T, Sekiguchi N, Matsushita H, Kasahara Y,
Mamiya K, Koizumi T : Successful Salvage Chemotherapy
with Mediastinal Atypical Carcinoid Tumor Who Had
Relapsed after Various Prior Therapies. Case Rep Oncol 11:49-54, 2018.
20180427
Fukushima T, Wakatsuki Y, Kobayashi T,
Sonehara K, Tateishi K, Yamamoto M, Masubuchi T,
Yoshiike F, Hirai K, Hachiya T, Koizumi T : Phase II
study of cisplatin/pemetrexed combined with bevacizumab
followed by pemetrexed/bevacizumab maintenance therapy
in patients with EGFR-wild advanced non-squamous nonsmall cell lung cancer. Cancer Chemother Pharmacol 81(6):1043-1050, 2018.
20180428

Gomi D, Fukushima T, Kobayashi T, Sekiguchi

29

N, Sakamoto A, Mamiya K, Koizumi T : Gastric cancer
initially presenting as bone metastasis: Two case reports anda literature review. Oncol Lett 16: 5863-5867, 2018.

5-S-cysteinyldopa behavior in the early phase of nivolumab
treatment of 12 melanoma patients. J Dermatol 45: 13401344, 2018.

20180429
Gubin MM, Esaulova E, Ward JP, Malkova ON,
Runci D, Wong P, Noguchi T, Arthur CD, Meng W, Alspach
E, Medrano RFV, Fronick C, Fehlings M, Newell EW,
Fulton RS, Sheehan KCF, Oh ST, Schreiber RD, Artyomov
MN : High-Dimensional Analysis Delineates Myeloid andLymphoid Compartment Remodeling during Successful
Immune-Checkpoint Cancer Therapy. Cell 175 (4): 10141030, 2018.

20180437
Sakaizawa T, Matsumura T, Fujii C, Hida
S, Toishi M, Shiina T, Yoshida K, Hamanaka K, Ito KI,
Taniguchi S : Potential Role of ASC, a Proapoptotic Protein,for Determining the Cisplatin Susceptibility of Lung Cancer
Cells. Tohoku J Exp Med 244(2): 133-144, 2018.

20180430
Handa H, Gomi D, Fukushima T, Kobayashi
T, Sekiguchi N, Sakamoto A, Tsukahara Y, Matsushita H,
Sasaki S, Mamiya K, Koizumi T, Ichiyama T : Signet Ring
Cell Carcinoma of Unknown Primary Origin Detected
Incidentally by Lymph Node Purification for Thyroid
Carcinoma. Intern Med 57(1): 31-35, 2018.
20180431
Kato A, Yasuo M, Tokoro Y, Kobayashi T,
Ichiyama T, Tateishi K, Ushiki A, Urushihata K, Yamamoto
H, Hanaoka M : Virtual bronchoscopic navigation as an aid
to CT-guided transbronchial biopsy improves the diagnostic
yield for small peripheral pulmonary lesions. Respirology
23(11): 1049-1054, 2018.
20180432
Kawakami T, Sekiguchi N, Kobayashi J, Imi T,
Matsuda K, Yamane T, Nishina S, Senoo Y, Sakai H, Ito T,
Koizumi T, Hirokawa M, Nakao S, Nakazawa H, Ishida F: Frequent STAT3 mutations in CD8+ T cells from patientswith pure red cell aplasia. Blood Adv 2(20): 2704-2712,
2018.
20180433
Koizumi T, Shetty V, Yamaguchi M : Salivary
cytokine panel indicative of non-small cell lung cancer. J Int
Med Res 46(9): 3570-3582, 2018.
20180434
Matsumura T, Hida S, Kitazawa M, Fujii C,
Kobayashi A, Takeoka M, Taniguchi SI, Miyagawa SI :Fascin1 Suppresses RIG-I-like Receptor Signaling andInterferon-β Production by Associating with IκB Kinase ϵ(IKK ϵ) in Colon Cancer. J Biol Chem 293(17): 6326-6336,
2018.

20180438
Sekiguchi N, Gomi D, Noguchi T, Kobayashi
T, Koizumi T, Fujita A, Kawakami S : Intradiaphragmatic
Bronchogenic Cysts: A Case Report and Literature Review.
OMICS J Radiol 7(1): 1000289, 2018.
20180439
Sogawa Y, Nagasu H, Itano S, Kidokoro K,
Taniguchi S, Takahashi M, Kadoya H, Satoh M, Sasaki T,
Kashihara N : The eNOS-NO pathway attenuates kidney
dysfunction via suppression of inflammasome activationin aldosterone-induced renal injury model mice. PLoS One
13(10): e0203823, 2018.
20180440
Yanagisawa R, Koizumi T, Koya T, Sano K,
Koido S, Nagai K, Kobayashi M, Okamoto M, Sugiyama
H, Shimodaira S : WT1-pulsed Dendritic Cell Vaccine
Combined with Chemotherapy for Resected Pancreatic
Cancer in a Phase I Study. Anticancer Res 38(4): 22172225, 2018.

Infection and Host Defense
20180441
Desamero MJ, Kakuta S, Chambers JK, Uchida
K, Hachimura S, Takamoto M, Nakayama J, Nakayama
H, Kyuwa S : Orally administered brown seaweed-derived
β-glucan effectively restrained development of gastric
dysplasia in A4gnt KO mice that spontaneously develop
gastric adenocarcinoma. Int Immunopharmacol 60: 211-220,2018.
20180442
Piao LX, Cheng JH, Aosai F, Zhao XD, Norose
K, Jin XJ : Cellular immunopathogenesis in primary
Toxoplasma gondii infection during pregnancy. Parasite
Immunol 40: e12570, 2018.

Brain Disease Research
20180435
Miura K, Hamanaka K, Matsuoka S, Takeda
T, Agatsuma H, Hyogatani A, Ito K, Nishimaki F, Koizumi
T, Uehara T : Primary Mediastinal dedifferentiatedliposarcoma: Five case reports and a review. Thorac Cancer
9(12): 1733-1740, 2018.

20180443
Verheijen BM, Oyanagi K, van Leeuwen FW: Dysfunction of protein quality control in parkinsonismdementia complex of Guam. Frontiers in Neurology 9: 173,2018.

20180436
Omodaka T, Minagawa A, Uhara H, Wakamatsu
K, Koizumi T, Yokokawa Y, Koga H, Okuyama R : Serum

20180444
Kobayashi M, Sakai Y, Kariya S, Sakai H,
Hineno A, Oyanagi K, Kanno Y : First pathological report

30

of a denovo CD5-positive diffuse large B-cell lymphoma
patient presenting with Guillain-Barré syndrome-likeneuropathy due to neurolymphomatosis. Neuropathology 38:
417-421, 2018.

K, Yokoe Y, Mizusawa A, Ota N, Shibata N, Tsuchiya K,
Hayashi M, Shiina I, Shimonaka M : Anti-proliferative
effect of ridaifen-B on hepatoma cells. Biomed Rep 9: 175180, 2018.

20180445
Shintaku M, Kaneda D, Oyanagi K :Atypical lower motor neuron disease with enlargementof Nissl substance: report of an autopsy case. Clinical
Neuropathology 37: 74-81, 2018.

20180453
Wa t a n a b e - A s a k a T, O d a S , M i t a n i H :Development of a Misrepair Visualization Assay in the Live
Embryo of Oryzias latipes by Partial Duplication System.
Cytologia 83: 221-222, 2018.

20180446
Yoshida K, Kuwabara S, Nakamura K, Abe R,
Matsushima A, Beppu M, Yamanaka Y, Takahashi Y, Sasaki
H, Mizusawa H, on behalf of The Research Group on Ataxic
Disorders : Idiopathic cerebellar ataxia (IDCA): diagnostic
criteria and clinical analyses of 63 Japanese patients. J
Neurol Sci 384: 30-35, 2018.

20180454
Sayed A E D H, Watanabe-Asaka T, Oda S,
Kashiwada S, Mitani H : γ-H2AX foci as indication for the
DNA damage in erythrocytes of medaka (Oryzias latipes)
intoxicated with 4-nonylphenol. Environ Sci Pollut Res : ,2018.

Hearing Implant Sciences
20180447
Konno T, Yoshida K, Mizuta I, Mizuno T,
Kawarai T, Tada M, Nozaki H, Ikeda S-I, Onodera O,
Wszolek ZK, Ikeuchi T : Diagnostic Criteria for adult-onset
leukoencephalopathy with axonal spheroids and pigmented
glia due to CSF1R mutation. Eur J Neurol 25: 142-147,
2018.
20180448
Yahikozawa H, Miyatake S, Sakai T, Uehara
T, Yamada M, Hanyu N, Futatsugi Y, Doi H, Koyano S,
Tanaka F, Suzuki A, Matsumoto N, Yoshida K : A Japanesefamily of spinocerebellar ataxia type 21: clinical andneuropathological studies. Cerebellum 17: 525-530, 2018.

20180455
Takahashi M, Arai Y, Sakuma N, Yabuki K,
Sano D, Nishimura G, Oridate N, Usami SI : Cochlear
volume as a predictive factor for residual-hearing
preservation after conventional cochlear implantation. Acta
otolaryngol. 138(4): 345-350, 2018.
20180456
Moteki H, Fujinaga Y, Goto T, Usami SI :Pneumolabyrinth, intracochlear and vestibular fluid loss
after cochlear implantation. Auris Nasus Larynx. 45: 11161120, 2018.

General Medicine
20180449
Mizukami N, Takeuchi S, Tetsuya M, Tsukahara
A, Hashimoto M, Yoshida K, Matsushima A, Maruyama
Y, Tako K : Effect of the synchronization-based control ofa wearable robot having a non-exoskeletal structure on thehemiplegic gait of stroke patients. IEEE Trans Neural Syst
Rehabil Eng 26: 1011-1016, 2018.

20180457
Gotaro Kojima, C. Avgerinou, S. Iliffe, S.
Jivraj, K. Sekiguchi, and K. Walters : Fruit and Vegetable
Consumption and Frailty: A Systematic Review. J Nutr
Health Aging. 22(8): 1010-1017, 2018.

Radiology Division
20180450
Tsukahara A, Yoshida K, Matsushima A, Ajima
K, Kuroda C, Mizukami N, Hashimoto M : Effects ofgait support in patients with spinocerebellar degeneration
by a wearable robot based on synchronization control. J
NeuroEng Rehabili 15: 84, 2018.

Innovation of Medical and Health Sciences
Research
20180451
Ajima K, Kawai Y, Maejima D, Suzuki S,
Yano S, Hayashi M, Katsumata A, kaidoh M, Yokoyama Y,
Ohhashi T : Lymph drainage from the chylocyst-induced
hemodilution in an in vivo rabbit study. Lymphat Res Biol
16: 154-159, 2018.
20180452

Hasegawa G, Akatsuka K, Hiruma K, Suda

20180458
Kurozumi M, Fujinaga Y, Kitou Y, Yamada A,
Ohya A, Adachi Y, Tsukahara Y, Nichel MD, Maruyama
K, Uehara T, Miyagawa S, Kadoya M : Evaluationof hemodynamic imaging findings of hypervascularhepatocellular carcinoma: comparison between dynamic
contrast-enhanced magnetic resonance imaging using radial
volumetric imaging breath-hold examination with k-spaceweighted image contrast reconstruction and dynamic
computed tomography during hepatic arteriography. Jpn JRadiol 36: 295-302, 2018.
20180459
M a t s u o k a D , H i d a k a Y, K u r o z u m i M ,Tsukahara Y, Nakazawa Y : Childhood asymptomatic renalarteriovenous fistula 5 years after renal biopsy. Pediatr Int
60: 601-602, 2018.

31

Blood Transfusion Center
20180460
Yanagisawa R, Kubota N, Hidaka E, Sakashita
K, Tanaka M, Nakazawa Y, Nakamura T : Cisplatin-induced
nephrotoxicity in patients with advanced neuroblastoma.
Pediatr Blood Cancer 65: e27253, 2018.

20180468
U e h a r a M , N a k a m u r a Y, Ta k a h a s h i J ,Kamimura M, Isobe F, Yamaguchi T, Kosho T, Uchiyama
S, Suzuki T, Kato H : Efficacy of denosumab therapy forneurofibromatosis type 1 with osteoporosis and history of
fractures: a case report. Ther Clin Risk Manag. 14: 12431246, 2018.

Intractable Disease Care Center
20180461
Kojima S, Yanagisawa R, Tanaka M, Nakazawa
Y, Shimodaira S : Comparison of administration of plateletconcentrates suspended in M-sol or BRS-A for pediatricpatients. Transfusion 58: 2952-2958, 2018.
20180462
Kobayashi J, Yanagisawa R, Ono T, Tatsuzawa
Y, Tokutake Y, Kubota N, Hidaka E, Sakashita K, Kojima
S, Shimodaira S, Nakamura T : Administration of plateletconcentrates suspended in bicarbonated Ringer's solution inchildren who had platelet transfusion reactions. Vox Sang
113: 128-135, 2018.

Medical Informatics
20180463
Hamano H, Tanaka E, Ishizaka N, Kawa S :IgG4-related Disease - A Systemic Disease that Deserves
Attention Regardless of One's Subspecialty. Intern Med 57:
1201-1207, 2018.

Center for Medical Genetics
20180464
Koitabashi N, Yamaguchi T, Fukui D, Nakano
T, Umeyama A, Toda K, Funada R, Ishikawa M, Kawamura
R, Okada K, Hatamochi A, Kosho T, Kurabayashi M :Peripartum Iliac Arterial Aneurysm and Rupture in a Patientwith Vascular Ehlers-Danlos Syndrome Diagnosed by Next
Generation Sequencing. Int Heart J in press 59: 1180-1185,
2018.
20180465
Natsume T, Takano K, Motobayashi M, Kosho
T : Hepatomegaly in a boy with ARID1B-related CoffinSiris syndrome. Pediatr Int. 60: 378-380, 2018.
20180466
Yoshida K, Kuwabara S, Nakamura K, Abe R,
Matsushima A, Beppu M, Yamanaka Y, Takahashi Y, Sasaki
H, Mizusawa H; Research Group on Ataxic Disorders :Idiopathic cerebellar ataxia (IDCA): Diagnostic criteria andclinical analyses of 63 Japanese patients. J Neurol Sci. 384:
30-35, 2018.
20180467
K o b a y a s h i T, N a k a m u r a Y, S u z u k i T,
Yamaguchi T, Takeda R, Takagi M, Hasegawa T, Kosho T,
Kato H : Efficacy and Safety of Denosumab Therapy for
Osteogenesis Imperfecta Patients with Osteoporosis-Case
Series. J Clin Med. 7: 479, 2018.

20180469
Ikeda S, Hineno A, Ozawa K, Kinoshita
T : Review; Suspected adverse effects after humanpapillomavirus vaccination: a temporal relationship.
Immunol Res 66: 723-725, 2018.

Neuroendovascular Therapy Center
20180470
Koyama J, Hanaoka Y, Kiuchi T, Sasaki T,
Murata T, Sato A, Hongo K : Development of Simulator
System Using Endovascular Evaluator for Catheter
Intervention Training. Journal of Neuroendovascular
Therapy 12: 1-5, 2018.

Advence Center for Cellular Therapy
20180471
Yanagisawa R, Koizumi T, Koya T, Sano K,
Koido S, Nagai K, Kobayashi M, Okamoto M, Sugiyama
H, Shimodaira S : WT1-pulsed Dendritic Cell Vaccine
Combined with Chemotherapy for Resected Pancreatic
Cancer in a Phase I Study. Anticancer Res 38: 2217-2225,
2018.
20180472
Hirabayashi K, Yanagisawa R, Saito S, Higuchi
Y, Koya T, Sano K, Koido S, Okamoto M, Sugiyama
H, Nakazawa Y, Shimodaira S : Feasibility and Immune
Response of WT1 Peptide Vaccination in Combination with
OK-432 for Paediatric Solid Tumors. Anticancer Res 38:
2227-2234, 2018.

Cochlear Implant Center
20180473
Takahashi M, Arai Y, Sakuma N, Yabuki K,
Sano D, Nishimura G, Oridate N, Usami SI : Cochlear
volume as a predictive factor for residual-hearing
preservation after conventional cochlear implantation. Acta
otolaryngol. 138(4): 345-350, 2018.
20180474
Moteki H, Fujinaga Y, Goto T, Usami SI :Pneumolabyrinth, intracochlear and vestibular fluid loss
after cochlear implantation. Auris Nasus Larynx. 45: 11161120, 2018.

32

Department of Pharmacy
20180475
Yamaori S, Araki N, Shionoiri M, Ikehata
K, Kamijo S, Ohmori S, Watanabe K : A Specific probe
substrate for evaluation of CYP4A11 activity in humantissue microsomes and a highly selective CYP4A11
inhibitor: luciferin-4A and epalrestat. J Pharmacol Exp Ther
366: 446-457, 2018.
20180476
Uchida T, Wakasugi M, Kitamura T, Yamamoto
T, Asakura M, Fujiwara R, Itoh T, Fujii H, Hirono S :Exploration of DPP-IV inhibitors with a novel scaffold bymultistep in silico screening. J Mol Graph Model 79: 254263, 2018.
20180477
Katane M, Ariyoshi M, Tateishi S, Koiwai S,
Takaku K, Nagai K, Nakayama K, Saitoh Y, Miyamoto
T, Sekine M, Mita M, Hamase K, Matoba S, Homma
H : Structural and enzymatic properties of mammalian
D-glutamate cyclase. Arch Biochem Biophys 654: 10-18,
2018.

Medical Safety Management Room
20180478
Son D, Shimizu I, Ishikawa H, Aomatsu
M, Leppink J : Communication skills training and theconceptual structure of empathy among medical students.
Pers Med Educ 7: 264-271, 2018.

Animal Research
20180479
Ding X, Liu Y, Yang M, Li L, Miyahara H,
Dai J, Xu Z, Matsumoto K, Mori M, Higuchi K, Sawasita
J : Amyloidosis-inducting activity of blood cells in mouse
AApoAll amyloidosis. . Experimental Animals 67: 105-115,
2018.
20180480
Yoshizawa T, Mizumoto S, Takahashi Y,
Shimada S, Sugahara K, Nakayama J, Takeda S, Nomura
Y, Nitahara-Kasahara Y, Okada T, Matsumoto K, YamadaS, and Kosho T : Vascular abnormalities in the placenta of
Chst14-/- fetuses: implications in the pathophysiology ofperinatal lethality of the murine model and vascular lesions
in human CHST14/D4ST1 deficiency. Glycobiology 28:
80-89, 2018.
20180481
Uekawa A, Yamanaka H, Lieben L, KimiraY, Uehara M, Yamamoto Y, Kato S, Ito K, Carmeliet
G, Masuyama R : Phosphate-dependent luminal ATP
metabolism regulates transcellular calcium transport inintestinal epithelial cells. The FASEB Journal 32: 19031915, 2018.

33

補

遺
No．46
2017

35

Internal Medicine 2
20170474
Hihara Y, Joshita S, Takahashi T, Okaniwa S,
Mizukami Y, Nakamura Y : A Patency Capsule Remained
Intact in the Colon over 210 Hours. Case Rep Gastrointest
Med 2017: 1201404, 2017.

Internal Medicine 3
20170475
Victor RG, Sweeney HL, Finkel R, McDonald
CM, Byrne B, Eagle M, Goemans N, Vandenborne K,
Dubrovsky AL, Topaloglu H, Miceli MC, Furlong P, Landry
J, Elashoff R, Cox D; Tadalafil DMD Study Group : A
phase 3 randomized placebo-controlled trial of tadalafil for
Duchenne muscular dystrophy. Neurology 89: 1811-1820,
2017.

Brain Disease Research
20170476
Hashimoto T, Muralidharan A, Yoshida K,
Goto T, Yako T, Baker KB, Vitek JL : Neuronal activity andoutcomes from thalamic surgery for spinocerebellar ataxia.
Ann Clin Translation Neurol 5: 52-63, 2017.

Center for Medical Genetics
20170477
Malfait F, Francomano C, Byers P, Belmont
J, Berglund B, Black J, Bloom L, Bowen JM, Brady AF,
Burrows NP, Castori M, Cohen H, Colombi M, Demirdas
S, De Backer J, De Paepe A, Fournel-Gigleux S, Frank M,
Ghali N, Giunta C, Grahame R, Hakim A, Jeunemaitre X,
Johnson D, Juul-Kristensen B, Kapferer-Seebacher I, Kazkaz
H, Kosho T, Lavallee ME, Levy H, Mendoza-Londono R,
Pepin M, Pope FM, Reinstein E, Robert L, Rohrbach M,
Sanders L, Sobey GJ, Van Damme T, Vandersteen A, vanMourik C, Voermans N, Wheeldon N, Zschocke J, Tinkle B.
: The 2017 international classification of the Ehlers-Danlos
syndromes.. Am J Med Genet C Semin Med Genet. 175:
8-26, 2017.
20170478
Brady AF, Demirdas S, Fournel-Gigleux
S, Ghali N, Giunta C, Kapferer-Seebacher I, Kosho T,
Mendoza-Londono R, Pope MF, Rohrbach M, Van Damme
T, Vandersteen A, van Mourik C, Voermans N, Zschocke
J, Malfait F. : The Ehlers-Danlos syndromes, rare types..
Am J Med Genet C Semin Med Genet. 175: 70-115, 2017.
20170479
Mizumoto S, Kosho T, Yamada S, Sugahara
K. : Pathophysiological Significance of Dermatan Sulfate
Proteoglycans Revealed by Human Genetic Disorders..
Pharmaceuticals (Basel). 10: 34, 2017.

20170480
Ideta H, Uchiyama S, Hayashi M, Kosho T,
Nakamura Y, Kato H. : Painful locking of the wrist in apatient with pseudoachondroplasia confirmed by COMP
mutation.. J Surg Case Rep. 2017: rjw216, 2017.

Animal Research
20170481
Ono A, Yoshizawa T. Matsumoto K : Evaluationof necessity of 1-year toxicity study in dogs- developmentof the new tired approach for toxicity studies of pesticideconsidering species difference in “toxicity profile” and“toxicity dose-response”. Food Safety 6: 109-117, 2017.

信大
州学
大医
学学
医部
学業
部績
業録
績編
録集
編要
集項
要（
項抜粋）
信州
（平成28年12月29日改正）

１．収録対象 ２．収録対象
 信州大学医学部医学科・大学院医学系研究科・医学部附属病院及び出版委員会で信州大学医学部医学科・大学院医学系研究科・医学部附属病院及び出版委員会で認めた施設等に所属する者（当該年に在籍した者全員）認めた施設等に所属する者（当該年度に在籍した者全員）
２．収録内容 ３．収録内容
収録対象は、本文が欧文で執筆された研究業績とし、次の３項目に分ける。
研究業績を次の２項目に分ける。
１）論文
１）論文
原著、綜説、展望、症例報告、速報、予報で、査読のある学術雑誌に発表のもの。
原著、綜説、展望、症例報告、速報、予報で学術雑誌に発表のもの。
学術集会記録（全国的又は世界的規模の集会記録で、原著論文と同様の内容をも
学術集会記録（全国的又は世界的規模の集会記録で、原著論文と同様の内容をもち、ち、別刷が発行されているもの）
別刷が発行されているもの）
２）著書
２）著書
単行書、分担執筆。
単行書、分担執筆。
３）その他
治療指針、トピックス、事典等、専門的知見にもとづき執筆された、論文形式の
ただし、以下のものは除外する。
記事（イ）学会発表の抄録（邦文、欧文を問わない。論文型式をとっていても学会発表に関するもの及び１頁ものの速報は抄録とみなす）
ただし、以下のものは除外する。
（ロ）セミナー、シンポジウム、その他の講演のテキストないし記録。
（イ）学会発表の抄録（邦文、欧文を問わない。論文型式をとっていても学会発表（ハ）業務報告書（文部科学省、厚生労働省、その他助成機関への研究報告書）
に関するもの及び１頁ものの速報は抄録とみなす）（ニ）座談会記事。
（ロ）セミナー、シンポジウム、その他の講演のテキストないし記録。
（ホ）学会記。
務報告書（文部科学省、厚生労働省、その他助成機関への研究報告書）（ハ）業and（ヘ）質疑応答（ＱＡ）、治療指針、問題集の解説、トピックス、話題、グラビア、
（ニ）
座
談会記事。
事典等に類するもの。
（ホ）学会記。
（ト）新聞記事、教育に関する記事、人物紹介、書評、随筆など学術性が認められ（ヘ）論文形式をとらない質疑応答（Q and A）、問題集の解説、話題、グラビア等ないもの。
に類するもの。
（チ）著者表示が団体名で個人の著者性が認められないもの。
（ト）新聞・週刊誌記事、教育に関する記事、人物紹介、書評、随筆など学術性が（リ）学術雑誌とは認められないものに発表したもの。
認められないもの。
（ヌ）訳本及び訳論文。
（チ）著者表示が団体名で個人の著者性が認められないもの。
４．収録期間
毎年１月～12月

あ

と

が

き

信州大学医学部医学科・大学院医学系研究科・医学部附属病院業績録第47号をお届けします。
本業績録は過去１年間、各教室や部門などでなされた４つの活動（研究活動、教育活動、診
信州大学医学部医学科・大学院医学系研究科・医学部附属病院業績録第 38 号をお届けします。
療活動、社会貢献）のうち、研究活動の成果として公表された論文を中心にまとめたものです。
自己点検、自己評価、学内・学外への報告において、本業績録の役割は重要と思われます。こ
本業績録は過去１年間、各講座や部門等でなされた４つの活動（研究、教育、診療、社会貢献）の１年の研究活動を振り返り、今後の方向性を考える契機にしていただければ幸いです。
のうち、研究活動の成果として公表された論文を中心にまとめたものです。自己点検、自己評
学術論文が公表されるまでには大変なエネルギーが必要となります。各著者の研究は、医学
価、学内外への報告において、本業績録の果たす役割は重要と思われます。このような観点から、医療における問題や疑問から解明したい目的を定め、その目的を達成するために具体的研究計
この１年間の研究活動を振り返り、今後の方向性等を考える契機にしていただけたら幸いに存画を立て、資金を調達し、倫理審査を受け、実験あるいは臨床研究を行ってデータを集め、デーじます。
タと対峙し考え、人にいかにわかりやすく伝えるかを熟考しながら執筆し、投稿先を定め、査読を受け、査読者と編集委員長と議論を重ねて内容を深めて承諾を受け、晴れて学術論文として日の目を見ます。2018年度の医学部の英文論文数は491本でした。研究経費確保の困難さ、今年度の英文論文総数は昨年度より微減し、90 年度以降で最も少ない 386 という結果となり
人員不足、診療業務の増加など研究活動にかけるエフォート確保が難しい中で、少しずつそのました。しかしながら、単なる総数のみの評価が必ずしも適切であるとは言えず、今年度の業論文業績総数が増加していることにつき、すべての信州大学医学部の著者に敬意を表します。
出版委員として、公表された論文それぞれに著者のエネルギーが凝縮されていることを感じな
績の中には極めて質の高い研究成果も少なくありません。今日、卒業生の大学離れや医学科入がら、業績録への記録の是非をチェックさせていただきました。
学定員数増加等により、診療や教育活動等の業務負荷は増加の一途にあります。このような現粗悪学術誌（いわゆるハゲタカジャーナル）が問題となっております。学術業績の高い研究状ではありますが、研究活動は大学が大学であるための大きな責務であり、外部評価基準の重者の下には、日々そのような雑誌への投稿や原稿査読の依頼が届いていることと思います。今回の業績チェックでも、そのような雑誌や雑誌社に該当しないかをしっかりと評価いたしまし
要項目であることは言うまでもありません。今後、各講座・部門等でのさらなる研究の発展をた。信州大学「オープンアクセスジャーナル投稿ガイドライン」https://www.shinshu-u.ac.jp/
祈念致します。
hq/research-integrity/news/asset_items/74yakubu_07.pdfをご投稿や査読前にぜひご参照下さい。
世界中で新型コロナウイルス感染症が深刻化して、教育・診療・研究ほか、あらゆる面で行
最後に、本業績録の編集にあたりご尽力頂きました先生方、図書館職員の方々に厚く御礼申
動制限が要されております。このような時こそ、信州大学医学部として根拠に基づいた学術活動を行い社会貢献に努めるべきと強く思います。
し上げます。
最後に、本業績録の編集にあたりご尽力頂きました先生方、図書館職員の方々に厚く御礼申
浅村英樹
し上げます。
 出 版 委 員 長：浅村英樹
杠 俊介
出 版 委 員：奥山隆平、石田文宏、川股知之
出 版 委 員 長：杠 俊介
出医学部図書館主査：石坂憲司
版 委 員：古庄知己、和田有子、小山淳一
医 学 部 図 書 館：後閑壮登

信州大学医学部医学科・大学院医学系研究科
・医学部附属病院業績録 第
第 47
38 号
号
平成
年１月
28 日印刷日印刷
令和 23
2年
6 月 19平成年１月
28 日発行日発行
令和 23
2年
6 月 19
編集兼 信 州 大 学 医 学 部
発行者 松本市旭 3 丁目 1 の 1
印刷所

藤原印刷株式会社

松本市新橋 7 の 21 番地

ISSN 1881ー4980

信 州 大 学 医 学 部 医 学 科・大 学 院 医 学 系 研 究 科・医 学 部 附 属 病 院 業 績 録

SCIENTIFIC ACHIEVEMENTS OF SHINSHU UNIVERSITY SCHOOL OF
MEDICINE, SHINSHU UNIVERSITY GRADUATE SCHOOL OF MEDICINE,
AND SHINSHU UNIVERSITY HOSPITAL
信州大学医学部医学科・大学院医学系研究科・医学部附属病院業績録

No.47 (2018)

第四七号（二〇一八）
二〇一九

2019