Program
September 7 (Tuesday)
7:30- 9:10Free Breakfast for Participants

9:10- 10:10

Training Course 1: Immunology
Taishin Akiyama, University of Tokyo, Japan

10:10 - 10:20

Coffee Break

10:20 - 11:20

Training Course 2: Bacteriology
Tomoko Yamamoto, Chiba University, Japan

11:20 - 11:30

Coffee Break

11:30 - 12:30

Training Course 3: Virology
Makoto Takeda, National Institute of Infectious Diseases, Japan

12:30 - 13:30

Free Lunch for Training Course Attendees

13:30 - 14:30

Training Course 4: Parasitology
Hajime Hisaeda, Gunma University, JapanOpening Remarks

15:30

Tetsuro Matano, University of Tokyo, Japan
15:45 - 17:30

Session 1: Immunology (1)Chair: Andrea J. Sant, University of Rochester, USA

15:45

S1-1

16:15

S1-2 (P-079)

16:30

S1-3

17:00

S1-4

18:30 - 20:30

Shizuo Akira, Osaka University, Japan
Functional analysis of LPS-inducible genes, zc3h12a and JMJD3 by genetargetingKeishi Adachi, Nagasaki University, JapanTCR ligation induces distinct signaling pathways in naive versus
antigen-experienced human T cells
Paul M. Allen, Washington University School of Medicine, USA
Development of CD4+ helper T cells and their role in protective immunity toListeria monocytogenes infections
Takashi Saito, RIKEN, Japan
Direct regulation of T cell activation by TLR ligands

Welcome Party

September 8 (Wednesday)
7:30- 9:00Free Breakfast for Participants

9:00- 9:50Keynote Lecture 1
Chair: Chihiro Sasakawa, The University of Tokyo, Japan
Thomas F. Meyer, Max Planck Institute, Germany
A global approach to assess molecular interactions of Helicobacter pylori with
its host

9:50- 10:10

10:10 - 12:10

Coffee BreakSession 2: Bacteriology
Chairs: Ben Adler, Monash University, Australia
Hitomi Mimuro, The University of Tokyo, Japan10:10

S2-1

10:40

S2-2

11:10

S2-3 (P-091)

11:25

S2-4 (P-107)

11:40

S2-5

Takaaki Akaike, Kumamoto University, Japan
Cell Signaling for Antimicrobial Host Defense Mediated by Nitrated Cyclic
Nucleotide
Ben Adler, Monash University, Australia
How surface components of Pasteurella multocida affect virulence: a tale oftwo polysaccharides.
Yo Sugawara, Osaka University, Japan
Botulinum hemagglutinin targets E-cadherin to disrupt the intercellularepithelial barrier
Joon Haeng Rhee, Chonnam National University Medical School, South Korea
A Bacterial RTX Toxin Causes Programmed Necrotic Cell Deaththrough
VDAC-Mediated Mitochondrial Dysfunction.
Kazuhisa Sekimizu, The University of Tokyo, JapanUse of Silkworms for Evaluating Bacterial Pathogenicity and the Therapeutic
Effects of Antibiotics

12:10 - 13:30

Lunch Break (own)

13:30 - 15:00

Poster Session 1 (odd numbers)

15:00 - 15:10

Coffee Break

15:10 - 18:45

Session 3: Host-Pathogen Interaction (1)Chairs: Helen Quill, National Institute of Health, USA
Yasushi Kawaguchi, The University of Tokyo, Japan

15:10

S3-1

15:40

S3-2 (P-060)

15:55

S3-3

16:25

S4-2*

Kiyoshi Kita, The University of Tokyo, Japan
Novel enzymes of parasite mitochondria essential for their survival
Yutaka Handa, London Research Institute, UKThe role of the small GTPases RhoD and RhoA during vaccinia virus infection
Gregory A. Smith, Northwestern University, USA
Dynein recruitment, axon transport and neural dissemination of analpha-herpesvirus
Hualan Chen, Harbin Veterinary Research Institute, CAAS, China
Genetic Basis for the Transmission of H5N1 Avian Influenza Viruses in a
Mammalian Host

16:55 - 17:15

Coffee Break

17:15

S3-5 (P-018)

17:30

S3-6

18:00

S3-7

18:30S3-8 (P-086)

Hirotaka Imai, The University of Tokyo, JapanThe HA and NS Genes of Human H5N1 Influenza A Virus Contribute to its
High Virulence in Ferrets
Andrea J. Sant, University of Rochester, USA
Encounter with seasonal vaccines and viruses primes memory CD4 T cells
capable of recognizing the pandemic H1N1 influenza virus
Akio Abe, Kitasato University, Japan
Bordetella immune evasion by type III effectors
Takeshi Noda, Osaka University, Japan
Differential Molecular Mechanisms between Salmonella Autophagy andStarvation-induced Macroautophagy*S4-2 switched with S3-4 due to the schedule change of the speaker.

September 9 (Thursday)
7:30- 9:00Free Breakfast for Participants

9:00- 9:50Keynote Lecture 2
Chair: Hiroshi Kiyono, The University of Tokyo, Japan
Bruce Beutler, Scripps Research Institute, USA
Genetics, Questions, and Answers in Immunology

9:50- 10:10

10:10 - 12:10

Coffee BreakSession 4: Virology
Chairs: Gregory A. Smith, Northwestern University, USA
Yasuko Tsunetsugu-Yokota, NIID, Japan

10:10

S4-1

10:40

S3-4*

11:10

S4-3

11:40

S4-4

Tsuneo Morishima, Okayama University, Japan
Impact of Pandemic Influenza A (H1N1) among Children
Keizo Tomonaga, Osaka University, JapanAn intranuclear life cycle of bornavirus reveals novel interactions between
RNA virus and hostRobert W. Doms, University of Pennsylvania, USA
Using zinc-finger nucleases to inactivate HIV-1 coreceptors in vitro and in vivo
Tatsuo Shioda, Osaka University, Japan
Retrovirus restriction factor TRIM5α

12:10 - 13:30

Lunch Break (own)

13:30 - 15:00

Poster Session 2 (even numbers)

15:00 - 15:10

Coffee Break

15:10 - 18:30

Session 5: Host-Pathogen Interaction (2)Chairs: Nancy L. Haigwood, Oregon Science & Health University, USA
Ai Kawana-Tachikawa, The University of Tokyo, Japan

15:10

S5-1

E. John Wherry, Wistar Institute, USA
Regulating Memory T Cell Differentiation and Function during Chronic Viral
Infection
15:40
S5-2
Yasuko Tsunetsugu-Yokota, National Institute of Infectious Diseases, Japan
The impact of chemokine receptor usage of HIV-1 in the pathogenesis of HIV
infection
16:10 S5-3
Guido Silvestri, Emory University and Yerkes National Primate Research Center, USA
Immune activation and target cell restriction in HIV pathogenesis.
16:40
S5-4 (P-023)
Taisuke Izumi, Kyoto University, Japan
Model structure of APOBEC3G N-terminal region reveals a biding pocket
modulating HIV-1 Vif interaction and RNA required for encapsidation
16:55- 17:15

Coffee Break

17:15

S5-5

17:45

S5-6 (P-077)

18:00

S5-7

Klaus Früh, Oregon Health & Science University, USA
Induction and evasion of innate and adaptive immune responses bycytomegalovirus
Koji Hase, RIKEN, JapanThe epithelia-specific membrane trafficking factor AP-1B secures gut immune
homeostasis
Hiroshi Kiyono, The University of Tokyo, Japan
Mucosal chaperoning nanogel vaccine for the induction of protective immunity

19:00 - 21:00

BBQ Party

September 10 (Friday)
7:30- 9:00Free Breakfast for Participants

9:00- 11:35

Session 6: Parasitology
Chairs: Kirk W. Deitsch, Weill Cornell Medical College, USA
Tomoyoshi Nozaki, NIID, Japan

9:00

S6-1 (P-003)

9:15

S6-2

9:45

S6-3

Shiroh Iwanaga, Mie University, Japan
Transcription factor AP2-Sp and its target genes inmalarial sporozoites
Kazuyuki Tanabe, Osaka University, Japan
Intimate association of evolutionary history of the human malaria parasite,
Plasmodium falciparum, with ancient demography of modern humans
Ze-Guang Han, Chinese National Human Genome Center, China
Systems Biological Analysis of Schistosoma japonicum

10:15 - 10:35

Coffee Break

10:35

S6-4

11:05

S6-5 (P-004)

11:20

S6-6 (P-013)

Kirk W. Deitsch, Weill Cornell Medical College, USA
Antigenic variation by malaria parasites: mechanisms of transcriptional andtranslation gene silencing in Plasmodium falciparum
Masahiro Yamamoto, Osaka University, JapanA Toxoplasma kinase ROP18 is required for acute toxoplasmosis
Kazuyo Moro, Keio University, JapanThe role of natural helper cell in helminth infection.

11:35 - 13:00

Lunch Break (own)

13:00 - 14:45

Session 7: Immunology (2)Chair: Hisashi Arase, Osaka University, Japan

13:00

S7-1

13:30

S7-2

14:00

S7-3 (P-082)

14:15

S7-4

14:45

Toshinori Nakayama, Chiba University, Japan
CD4 T cell memory controlled by Polycomb and Trithorax molecules
John T. Harty, University of Iowa, USA
Antigen Re-encounter Modulates Differentiation and Protection by Memory
CD8 T cells
Satoshi Uematsu, Osaka University, Japan
Antigen-specific cytokine profiles and phenotypes in small intestinal Th17 cells
Hajime Karasuyama, Tokyo Medical and Dental University, Japan
Non-redundant role for basophils in antibody-mediated, acquired immunity
against ticks

Closing Remarks
Yoshiharu Matsuura, Osaka University, Japan