ISSN 1881ー4980

信 州 大 学 医 学 部 医 学 科・大 学 院 医 学 系 研 究 科・医 学 部 附 属 病 院 業 績 録

SCIENTIFIC ACHIEVEMENTS OF SHINSHU UNIVERSITY SCHOOL OF
MEDICINE, SHINSHU UNIVERSITY GRADUATE SCHOOL OF MEDICINE,
AND SHINSHU UNIVERSITY HOSPITAL
信州大学医学部医学科・大学院医学系研究科・医学部附属病院業績録

No.46 (2017)

第四六号（二〇一七）
二〇一八

2018

信大
州学
大医
学学
医部
学業
部績
業録
績編
録集
編要
集項
要（
項抜粋）
信州

あ

（平成28年12月29日改正）

１．収録対象 ２．収録対象
 信州大学医学部医学科・大学院医学系研究科・医学部附属病院及び出版委員会で信州大学医学部医学科・大学院医学系研究科・医学部附属病院及び出版委員会で認めた施設等に所属する者（当該年に在籍した者全員）認めた施設等に所属する者（当該年度に在籍した者全員）
２．収録内容 ３．収録内容
収録対象は、本文が欧文で執筆された研究業績とし、次の３項目に分ける。
研究業績を次の２項目に分ける。
１）論文
１）論文
原著、綜説、展望、症例報告、速報、予報で、査読のある学術雑誌に発表のもの。
原著、綜説、展望、症例報告、速報、予報で学術雑誌に発表のもの。
学術集会記録（全国的又は世界的規模の集会記録で、原著論文と同様の内容をも
学術集会記録（全国的又は世界的規模の集会記録で、原著論文と同様の内容をもち、ち、別刷が発行されているもの）
別刷が発行されているもの）
２）著書
２）著書
単行書、分担執筆。
単行書、分担執筆。
３）その他
治療指針、トピックス、事典等、専門的知見にもとづき執筆された、論文形式の
ただし、以下のものは除外する。
記事（イ）学会発表の抄録（邦文、欧文を問わない。論文型式をとっていても学会発表に関するもの及び１頁ものの速報は抄録とみなす）
ただし、以下のものは除外する。
（ロ）セミナー、シンポジウム、その他の講演のテキストないし記録。
（イ）学会発表の抄録（邦文、欧文を問わない。論文型式をとっていても学会発表（ハ）業務報告書（文部科学省、厚生労働省、その他助成機関への研究報告書）
に関するもの及び１頁ものの速報は抄録とみなす）（ニ）座談会記事。
（ロ）セミナー、シンポジウム、その他の講演のテキストないし記録。
（ホ）学会記。
務報告書（文部科学省、厚生労働省、その他助成機関への研究報告書）（ハ）業and（ヘ）質疑応答（ＱＡ）、治療指針、問題集の解説、トピックス、話題、グラビア、
（ニ）
座
談会記事。
事典等に類するもの。
（ホ）学会記。
（ト）新聞記事、教育に関する記事、人物紹介、書評、随筆など学術性が認められ（ヘ）論文形式をとらない質疑応答（Q and A）、問題集の解説、話題、グラビア等ないもの。
に類するもの。
（チ）著者表示が団体名で個人の著者性が認められないもの。
（ト）新聞・週刊誌記事、教育に関する記事、人物紹介、書評、随筆など学術性が（リ）学術雑誌とは認められないものに発表したもの。
認められないもの。
（ヌ）訳本及び訳論文。
（チ）著者表示が団体名で個人の著者性が認められないもの。
４．収録期間
毎年１月～12月とがき

信州大学医学部医学科
・大学院医学系研究科・医学部附属病院業績録第46号をお届けします。
信州大学医学部医学科・大学院医学系研究科・医学部附属病院業績録第38 号をお届けします。
本業績録は過去１年間、各教室や部門などでなされた４つの活動（研究活動、教育活動、診本業績録は過去１年間、各講座や部門等でなされた４つの活動（研究、教育、診療、社会貢献）
療活動、社会貢献）のうち、研究活動の成果として公表された論文を中心にまとめたものです。
のうち、研究活動の成果として公表された論文を中心にまとめたものです。自己点検、自己評
自己点検、自己評価、学内・学外への報告において、本業績録の役割は重要と思われます。この１年の研究活動を振り返り、今後の方向性を考える契機にしていただければ幸いです。
価、学内外への報告において、本業績録の果たす役割は重要と思われます。このような観点から、
この１年間の研究活動を振り返り、今後の方向性等を考える契機にしていただけたら幸いに存
昨今、高額の掲載料を徴収し、レビューなしで科学的妥当性・信頼性を問わずに論文を掲載
じます。
するオープンアクセス誌「ハゲタカジャーナル」が横行していることは皆さまもよくご存じのことと思います。「ハゲタカジャーナル」の問題は、医師・研究者の間だけでなく一般のメディアにも取り上げられるようになり、2018年12月には文部科学大臣が「大変深刻な事態」と懸
今年度の英文論文総数は昨年度より微減し、90 年度以降で最も少ない 386 という結果となり念を表明するに至っています。それを受けて全国の大学や研究機関でも一斉にこの問題が議題ました。しかしながら、単なる総数のみの評価が必ずしも適切であるとは言えず、今年度の業に挙げられ、今後「ハゲタカジャーナル」を業績に加えた場合、業績がマイナス査定される可能性も示唆されています。信州大学でも「ハゲタカジャーナル」を如何に見極めるかが話し合
績の中には極めて質の高い研究成果も少なくありません。今日、卒業生の大学離れや医学科入われているところです。
学定員数増加等により、診療や教育活動等の業務負荷は増加の一途にあります。このような現
私は昨年度から出版委員会に参加させていただいておりますが、初めて参加した編集会議で状ではありますが、研究活動は大学が大学であるための大きな責務であり、外部評価基準の重は、膨大な労力をもって１つ１つの論文が丁寧に審査されていることに大変驚かされました。
要項目であることは言うまでもありません。今後、各講座・部門等でのさらなる研究の発展を委員長を務めさせていただいた本年度は、みなさまの知を結集した本業績集を自信を持って全国に発信できることを誇りに思っています。今後も世界に誇れるような研究成果が信州大学か祈念致します。
ら発信されていくことを祈念しております。
最後に、本業績録の編集にあたりご尽力頂きました先生方、図書館職員の方々に厚く御礼申
最後に、本業績録の編集にあたりご尽力頂きました先生方、図書館職員の方々に厚く御礼申し上げます。
し上げます。



中沢 洋三
浅村英樹

出出 版
版委
委員
員 長：中沢洋三
長：浅村英樹出出 版
委 員：杠 俊介、森 政之、和田有子
版 委 員：奥山隆平、石田文宏、川股知之
医 学 部 図 書 館：岩井雅史、後閑壮登
医学部図書館主査：石坂憲司

信州大学医学部医学科・大学院医学系研究科
・医学部附属病院業績録 第
第 46
38 号
号
平成
平成 23
31 年１月
年 1 月28
31日印刷
日印刷
平成
平成 23
31 年１月
年 1 月28
31日発行
日発行
編集兼 信 州 大 学 医 学 部
発行者 松本市旭 3 丁目 1 の 1
印刷所

藤原印刷株式会社

松本市新橋 7 の 21 番地

a

SCIENTIFIC ACHIEVEMENTS OFSHINSHU UNIVERSITY SCHOOL OF MEDICINE,SHINSHU UNIVERSITY GRADUATE SCHOOL OF MEDICINE,
AND SHINSHU UNIVERSITY HOSPITAL

信州大学医学部医学科・大学院医学系研究科・
医学部附 属 病 院 業 績 録
No. 46（ 2 0 1 7 ）

2018

b

1

I. Scientific Achievements of Shinshu University School of Medicine,
Shinshu University Graduate School of Medicine,and Shinshu University HospitalContents
Histology and Embryology...........................................3

Ophthalmology...........................................................21

Anatomy........................................................................3

Otorhinolaryngology...................................................21

Physiology....................................................................3

Obstetrics and Gynecology.........................................23

Molecular Cellular Physiology.....................................3

Anesthesiology and Resuscitology.............................23

Molecular Pharmacology..............................................3

Plastic and Reconstructive Surgery............................23

Pathology......................................................................3

Laboratory Medicine...................................................23

Pathobiology.................................................................4Emergency and Critical Care Medicine......................25

Microbiology and Immunology....................................4

Comprehensive Cancer Therapy.................................26

Medical Genetics..........................................................4

Infection and Host Defense.........................................27

Preventive Medicine and Public Health........................4

Brain Disease Research...............................................27

Legal Medicine.............................................................5

Innovation of Medical and Health Sciences Research....27

Regenerative Science and Medicine.............................5Drug Discovery Science.............................................28

Internal Medicine 1.......................................................6

Hearing Implant Sciences...........................................28

Internal Medicine 2.......................................................6

Aging Biology.............................................................28

Internal Medicine 3.......................................................8

Neuroplasticity............................................................29

Internal Medicine 4.....................................................10

Molecular Pathology...................................................29

Internal Medicine 5.....................................................10

Metabolic Regulation..................................................29

Psychiatry....................................................................12

Cardiovascular Research.............................................30

Pediatrics.....................................................................13

Sports Medical Sciences.............................................31

Dermatology...............................................................14

Radiology Division.....................................................31

Radiology....................................................................15

Blood Transfusion Center...........................................31

Surgery 1.....................................................................16

Rehabilitation Center..................................................31

Surgery 2.....................................................................16

Center for Medical Genetics.......................................31

Orthopaedic Surgery...................................................17

Center for Clinical Research.......................................32

Neurosurgery...............................................................19

Intractable Diseases Care Center................................32

Dentistry & Oral Surgery............................................20

Advence Center for Cellular Therapy.........................32

Urology.......................................................................21

Department of Pharmacy............................................32

2

3

Histology and Embryology
20170001
N a kam ura S, Taki zaw a S, Yok o y a m a T,
Tomotsune T, Yue F, Sasaki K : Simple Isolation of
Pancreatic Progenitor Cells from Human Induced Pluripotent
Stem Cells Using the ALDEFLUOR. Stem Cell Adv Res
Ther 2017: SCRT-111, 2017.
20170002
Yue F, Hirashima K, Tomotsune D, Takizawa S,
Yokoyama T, Sasaki K : Reprogramming of retinoblastoma
cancer cells into cancer stem cells. Biochem Biophys Res
Commun 482: 549-555, 2017.
20170003
Hirashima K, Yue F, Tomotsune D, Takizawa
S, Sasaki K : Cardiac portion of the stomach: a deep region
within the abdomen. Abdomen 4: e1550, 2017.

Anatomy20170004
Fukushima N, Karasawa M, Yokouchi K,
Sumitomo N, Kawagishi K, Moriizumi T : Stereologicalassessment of the total number of hypoglossal neurons after
repeated crush injuries to the hypoglossal nerve in adult rats.
Neurol Res 39: 183-188, 2017.

20170010
PrabhuDas MR, Baldwin CL, Bollyky PL,
Bowdish DME, Drickamer K, Febbraio M, Herz J, Kobzik
L, Krieger M, Loike J, McVicker B, Means TK, Moestrup
SK, Post SR, Sawamura T, Silverstein S, Speth RC, Telfer
JC, Thiele GM, Wang XY, Wright SD, El Khoury J : A
Consensus Definitive Classification of Scavenger Receptors
and Their Roles in Health and Disease. J Immunol 198:3775-3789, 2017.

Molecular Cellular Physiology
20170011
Miki T, Kaufmann WA, Malagon G, Gomez L,
Tabuchi K, Watanabe M, Shigemoto R, Marty A : Numbersof presynaptic Ca2+ channel clusters match those offunctionally defined vesicular docking sites in single central
synapses. Proc Natl Acad Sci U S A 114(26): E5246-E5255,
2017.
20170012
Baig DN, Yanagawa T, Tabuchi K : Distortionof the normal function of synaptic cell adhesion moleculesby genetic variants as a risk for autism spectrum disorders.
Brain Res Bull 129: 82-90, 2017.
20170013
Cao X, Tabuchi K : Functions of synapse
adhesion molecules neurexin/neuroligins andneurodevelopmental disorders. Neurosci Res 116: 3-9, 2017.

20170005
Fukushima N, Yokouchi K, Kuroiwa M,
Kawagishi K, Moriizumi T : Acetyl-l-carnitine enhances
myelination of regenerated fibers of the lateral olfactory
tract. Neurosci Lett 653: 215-219, 2017.

20170014
Takahashi H, Matsuda K, Tabuchi K, Ko J :Central synapse, neural circuit, and brain function. Neurosci
Res 116: 1-2, 2017.

Physiology

Molecular Pharmacology

20170006
Spaans F, Kao CK, Morton JS, Quon AL,
Sawamura T, Tannetta DS, Sargent IL, Davidge ST :Syncytiotrophoblast extracellular vesicles impair rat
uterine vascular function via the lectin-like oxidized LDL
receptor-1. PLoS One 12: e0180364, 2017.

20170015
Kashihara T, Nakada T, Kojima K, Takeshita T,
Yamada M : Angiotensin II activates CaV1.2 Ca2+ channels
through β arrestin2 and casein kinase 2 in mouse immature
cardiomyocytes. J Physiol 595: 4207-4225, 2017.

20170007
Ke LY, Chan HC, Chan HC, Kalu FCU, Lee
HC, Lin IL, Jhuo SJ, Lai WT, Tsao CR, Sawamura T, Dixon
RA, Chen CH, Chu CS, Shin SJ : Electronegative Lowdensity Lipoprotein L5 induces adipose tissue inflammation
associated with metabolic syndrome. J Clin Endocrinol
Metab 102: 4615-4625, 2017.
20170008
Sawamura T, Fujita Y, Horiuchi S, Kakino A :LOX-1 in ischemic stroke. J Atheroscler Thromb 24: 566568, 2017.
20170009
Sawamura T, Fujita Y, Horiuchi S, Kakino A :L5: an LDL fraction in which pathogenic activity of LDL isconcentrated. Trends Cardiovasc Med 27: 247-248, 2017.

Pathology
20170016
Ichimata S, Kobayashi M, Honda K, Shibata
S, Matsumoto A, Kanno H : Acquired amegakaryocytic
thrombocytopenia previously diagnosed as idiopathic
thrombocytopenic purpura in a patient with hepatitis C virus
infection. World J Gastroenterol 23: 6540-6545, 2017.
20170017
Yamamoto Y, Saito A, Tateishi A, Shimojo
H, Kanno H, Tsuchiya S, Ito KI, Cosatto E, Graf HP,
Moraleda RR, Eils R, Grabe N : Quantitative diagnosisof breast tumors by morphometric classification of
microenvironmental myoepithelial cells using a machinelearning approach. Sci Rep 7: 46732, 2017.

4

20170018
Ohya A, Higuchi K, Shimojo H, Fujinaga Y,
Kadoya M, Shiohara S : Epithelioid trophoblastic tumorof the uterus: A case report with radiologic-pathologic
correlation. J Obstet Gynaecol Res 43: 1360-1365, 2017.
20170019
Ohya A, Yamanoi K, Shimojo H, Fujii C,
Nakayama J : Gastric gland mucin-specific O-glycan
expression decreases with tumor progression from precursor
lesions to pancreatic cancer. Cancer Sci 108: 1897-1902,
2017.

20170026
Yoshinaga T, Nakamura K, Ishikawa M,
Yamaguchi T, Takano K, Wakui K, Kosho T, Yoshida K,
Fukushima Y, Sekijima Y : A novel frameshift mutationof SYNE1 in a Japanese family with autosomal recessive
cerebellar ataxia type 8. Hum Genome Var 4: 17052, 2017.

Pathobiology

20170027
Hori I, Kawamura R, Nakabayashi K, Watanabe
H, Higashimoto K, Tomikawa J, Ieda D, Ohashi K, Negishi
Y, Hattori A, Sugio Y, Wakui K, Hata K, Soejima H,
Kurosawa K, Saitoh S : CTCF deletion syndrome: clinicalfeatures and epigenetic delineation. J Med Genet 54: 836842, 2017.

20170020
Takeuchi Y, Shigemura T, Kobayashi N,
Kaneko N, Iwasaki T, Minami K, Kobayashi K, Masumoto
J, Agematsu K : Early diagnosis of early-onset sarcoidosis:
a case report with functional analysis and review of theliterature. Clin Rheumatol 36(5): 1189-1196, 2017.

20170028
Morikawa M, Takano K, Motobayashi M, Shiba
N, Kosho T, Nakazawa Y, Inaba Y : Clinical features ofa female with WDR45 mutation complicated by infantile
spasms: a case report and literature review. Brain Dev 39:
804-807, 2017.

20170021
Yamagami K, Nakamura T, Nakamura R,
Hanioka Y, Seki K, Chiba H, Kobayashi K, Agematsu K: Familial Mediterranean fever with P369S/R408Q exon3
variant in pyrin presenting as symptoms of PFAPA. Mod
Rheumatol 27(2): 356-359, 2017.

20170029
Mizumoto S, Kosho T, Hatamochi A, Honda T,
Yamaguchi T, Okamoto N, Miyake N, Yamada S, Sugahara
K : Defect in dermatan sulfate in urine of patients with
Ehlers-Danlos syndrome caused by a CHST14/D4ST1
deficiency. Clin Biochem 50: 670-677, 2017.

20170022
S higemura T, Motobayas hi M, M ats uda
K, Shimodaira T, Kurata T, Kobayashi N, Agematsu K,
Nakazawa Y : Acute Myeloid Leukemia in a Patient With
X-linked Severe Combined Immunodeficiency. J Pediatr
Hematol Oncol 39(8): e470-e472, 2017.

20170030
Fukuda Y, Higuchi Y, Shinozaki K, Tanigawa Y,
Abe T, Hanaoka N, Matsubayashi S, Yamaguchi T, Kosho
T, Nakamichi K : Mobile Cecum in a Young Woman with
Ehlers-Danlos Syndrome Hypermobility type: A Case Reportand Review of the Literature. Intern Med 56: 2791-2796,
2017.

20170023
Moroda M, Takamoto M, Iwakura Y, Nakayama
J, Aosai F : Interleukin-17A-Deficient Mice Are Highly
Susceptible to Toxoplasma gondii Infection Due to
Excessively Induced T. gondii HSP70 and Interferon Gamma
Production. Infect Immun 85(12): e00399-17, 2017.

Microbiology and Immunology
20170024
Kashihara T, Nakada T, Kojima K, Takeshita T,
Yamada M : Angiotensin II activates CaV 1.2 Ca2+ channels
through β-arrestin2 and casein kinase 2 in mouse immature
cardiomyocytes. J Physiol 595(13): 4207-4225, 2017.

Medical Genetics
20170025
Takano K, Goto K, Motobayashi M, Wakui K,
Kawamura R, Yamaguchi T, Fukushima Y, Kosho T : Early
manifestations of epileptic encephalopathy, brain atrophy,
and elevation of serum neuron specific enolase in a boy withbeta-propeller protein-associated neurodegeneration. Eur J
Med Genet 60: 521-526, 2017.

20170031
Oba H, Takahashi J, Takano K, Inaba Y,
Motobayashi M, Nishimura G, Kuraishi S, Shimizu M,
Ikegami S, Futatsugi T, Uehara M, Kosho T, Kato H,
Uno K : Rigid Occipitocervical Instrumented Fusion for
Atlantoaxial Instability in an 18-Month-Old Toddler With
Brachytelephalangic Chondrodysplasia Punctata: A Case
Report. Spine (Phila Pa 1976) 42: E1380-E1385, 2017.
20170032
Uehara M, Nakamura Y, Takahashi J, Kamimura
M, Ikegami S, Suzuki T, Uchiyama S, Yamaguchi T, Kosho
T, Kato H : Efficacy of Denosumab for Osteoporosis in
Three Female Patients with Osteogenesis Imperfecta.
Tohoku J Exp Med 242: 115-120, 2017.

Preventive Medicine and Public Health20170033
Noriyuki Kitagawa, Hiroaki Motoyama, Akira
Kobayashi, Takahide Yokoyama, Akira Shimizu, Tsuyoshi
Notake, Kentaro Fukushima, Hitoshi Masuo, Takahiro
Yoshizawa, Teruomi Tsukahara, Shin-ichi Miyagawa :Adjuvant Chemotherapy with Gemcitabine for Resected5Biliary Tract Cancer: A Single-Arm Phase 2 Study. Shinshu
Med J 65(2): 99-111, 2017.
20170034
Noriyuki Yoshioka, Toru Takebayashi, Yuji
Nishiwaki, Tetsuo Nomiyama, Satoko Iwasawa, Haruhiko
Sakurai, Kazuyuki Omae : Changes of median nerve
conduction velocity in rayon manufacturing workers: A sixyear cohort study. J Occup Health 59: 187-193, 2017.
20170035
The Committee for Recommendationof Occupational Exposure Limits, Japan Society for
Occupational Health, Kenichi Azuma, Ginji Endo, Yoko
Endo, Tetsuhito Fukushima, Kunio Hara, Hajime Hori,
Seichi Horie, Hyogo Horiguchi, Masayoshi Ichiba, Gaku
Ichihara, Masayuki Ikeda, Tatsuya Ishitake, Akiyoshi
Ito, Yuki Ito, Satoko Iwasawa, Michihiro Kamijima,
Kanae Karita, Takahiko Katoh, Toshio Kawai, Toshihiro
Kawamoto, Reiko Kishi, Shinji Kumagai, Yukinori Kusaka,
Akiko Matsumoto, Muneyuki Miyagawa, Hiroyuki
Miyauchi, Yasuo Morimoto, Kasuke Nagano, Hisao Naito,
Tamie Nakajima, Tetsuo Nomiyama, Hirokazu Okuda,
Kazuyuki Omae, Haruhiko Sakurai, Kazuhiro Sato,
Tomotaka Sobue, Yasushi Suwazono, Toru Takebayashi,
Tatsuya Takeshita, Akito Takeuchi, Ayano Takeuchi,
Masatoshi Tanaka, Shigeru Tanaka, Teruomi Tsukahara,
Masashi Tsunoda, Susumu Ueno, Jun Ueyama, Yumi
Umeda, Yuko Yamano, Takenori Yamauchi, Eiji Yano :Occupational exposure limits for ethylene glycol monobutyl
ether, isoprene, isopropyl acetate and propyleneimine, andclassifications on carcinogenicity, occupational sensitizer
and reproductive toxicant. J Occup Health 59: 364-366,
2017.

Legal Medicine
20170036
Ota M, Umemura T, Kawa S : Immunogeneticsof IgG4-Related AIP. Curr Top Microbiol Immunol 401:
35-44, 2017.
20170037
Carapito R, Gottenberg JE, Kotova I, Untrau M,
Michel S, Naegely L, Aouadi I, Kwemou M, Paul N, Pichot
A, Locke J, Bowman SJ, Griffiths B, Sivils KL, Sibilia J,
Inoko H, Micelli-Richard C, Nocturne G, Ota M, Ng WF,
Mariette X, Bahram S : A new MHC-linked susceptibility
locus for primary Sjögren's syndrome: MICA. Hum Mol
Genet 26: 2565-2576, 2017.
20170038
Joshita S, Umemura T, Tanaka E, Ota M :Genetic Contribution to the Pathogenesis of Primary Biliary
Cholangitis. J Immunol Res : 3073504, 2017.
20170039
Cole AM, Cox S, Jeong C, Petousi N, Aryal
DR, Droma Y, Hanaoka M, Ota M, Kobayashi N, Gasparini

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20170040
Horie Y, Meguro A, Ohta T, Lee EB, Namba
K, Mizuuchi K, Iwata D, Mizuki N, Ota M, Inoko H, Ishida
S, Ohno S, Kitaichi N : HLA-B51 Carriers are Susceptible
to Ocular Symptoms of Behçet Disease and the Association
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the Silk Road: A Literature Survey. Ocul Immunol Inflamm
25: 37-40, 2017.
20170041
Umemura T, Sekiguchi T, Joshita S, Yamazaki
T, Fujimori N, Shibata S, Ichikawa Y, Komatsu M,
Matsumoto A, Shums Z, Norman GL, Tanaka E, Ota M :Association between serum soluble CD14 and IL-8 levels
and clinical outcome in primary biliary cholangitis. Liver Int
37: 897-905, 2017.

Regenerative Science and Medicine
20170042
Mao D, Ando S, Sato S I, Qin Y, Hirata N,
Katsuda Y, Kawase E, Kuo T F, Minami I, Shiba Y, Ueda
K, Nakatsuji N, Uesugi M : A Synthetic Hybrid Molecule
for the Selective Removal of Human Pluripotent Stem Cells
from Cell Mixtures. Angew Chem Int Ed Engl 56(7): 17651770, 2017.
20170043
Ichimura H, Shiba Y : Recent Progress Using
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20170044
Ogasawara T, Okano S, Ichimura H, Kadota S,
Tanaka Y, Minami I, Uesugi M, Wada Y, Saito N, Okada K,
Kuwahara K, Shiba Y : Impact of extracellular matrix onengraftment and maturation of pluripotent stem cell-derived
cardiomyocytes in a rat myocardial infarct model. Sci Rep7(1): 8630, 2017.
20170045
Kadota S, Shiba N, Shiba Y : Cardiac Sodium
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20170046
Li J, Minami I, Shiozaki M, Yu L, Yajima S,
Miyagawa S, Shiba Y, Morone N, Fukushima S, Yoshioka
M, Li S, Qiao J, Li X, Wang L, Kotera H, Nakatsuji N, Sawa
Y, Chen Y, Liu L : Human Pluripotent Stem Cell-Derived
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20170047
Morikawa M, Takano K, Motobayashi M, Shiba
N, Kosho T, Nakazawa Y, Inaba Y : Clinical features ofa female with WDR45 mutation complicated by infantile

6

spasms: a case report and literature review. Brain Dev 39(9):804-807, 2017.
20170048
Nakamura A, Shiba N, Miyazaki D, Nishizawa
H, Inaba Y, Fueki N, Maruyama R, Echigoya Y, Yokota
T : Comparison of the phenotypes of patients harboring
in-frame deletions starting at exon 45 in the Duchenne
muscular dystrophy gene indicates potential for thedevelopment of exon skipping therapy. J Hum Genet 62(4):459-463, 2017.

Internal Medicine 1
20170049
Yasuo M, Kitaguchi Y, Komatsu Y, Hama
M, Koizumi T, Agatsuma T, Ichiyama T, Kato A, Moteki
H, Hanaoka M : Self-assessment of Allergic Rhinitis
and Asthma (SACRA) Questionnaire-based Allergic
RhinitisTreatment Improves Asthma Control in AsthmaticPatients with Allergic Rhinitis. Intern Med 56: 31-39, 2017.
20170050
Ushiki A, Nozawa S, Yasuo M, Urushihata
K, Yamamoto H, Hanaoka M, Fujimoto K : Associations
between the distance covered in the incremental shuttle
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33-38, 2017.
20170051
Ozawa Y, Yamamoto H, Yasuo M, Takahashi
H, Tateishi K, Ushiki A, Kawakami S, Fujinaga Y, Asaka
S, Sano K, Takayama H, Imamura H, Hanaoka M : Twopatients with TAFRO syndrome exhibiting strikingly
similar anterior mediastinal lesions with predominantly fat
attenuation on chest computed tomography. Respir Investig
55: 176-180, 2017.
20170052
Ueno F, Kitaguchi Y, Shiina T, Asaka S,
Miura K, Yasuo M, Wada Y, Yoshizawa A, Hanaoka M: The Preoperative Composite Physiologic Index May
Predict Mortality in Lung Cancer Patients with Combined
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20170053
Ikegawa K, Ota M, Kobayashi N, Droma
Y, Yaegashi H, Nishizawa M, Yasuo M, Urushihata K,
Yamamoto H, Hanaoka M : Lack of Association of Serotonin
2A Receptor Gene in Japanese Patients with Obstructive
Sleep Apnea Syndrome. Shinshu Med J 65: 153-162, 2017.
20170054
Nishie K, Yamamoto S, Nagata C, Koizumi T,
Hanaoka M : Anamorelin for advanced non-small-cell lungcancer with cachexia: Systematic review and meta-analysis.
Lung Cancer 112: 25-34, 2017.

20170055
Droma Y, Kato A, Ichiyama T, Kobayashi N,
Honda T, Uehara T, Hanaoka M : Electron Microscopy
Observation of Human Pulmonary Ultrastructure in Two
Patients with High-Altitude Pulmonary Edema. High Alt
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20170056
K o s a k a M , U s h i k i A , I k u y a m a Y, H i r a i
K, Matsuo A, Hachiya T, Hanaoka M : A Four-Center
Retrospective Study of the Efficacy and Toxicity of LowDose Trimethoprim-Sulfamethoxazole for the Treatment ofPneumocystis Pneumonia in Patients without HIV Infection.
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20170057
Nozawa S, Yasuo M, Yamamoto H, Hama
M, Tateishi K, Ushiki A, Hanaoka M : An unusual case ofmulticentric Castleman's disease, complicated by pleural
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20170058
Nishie K, Yasuo M,Takahashi H, Ozawa Y,
Tateishi K, Yamamoto H, Koiwai K, Uehara T, Ideura
G, Hanaoka M : Bronchial Mucoepidermoid Carcinoma
Successfully Treated with Radiation Therapy: A Case
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Internal Medicine 2
20170059
Fujimori N, Komatsu M, Tanaka N, Iwaya
M, Nakano H, Sugiura A, Yamazaki T, Shibata S, Iwaya
Y, Muraki T, Ichikawa Y, Kimura T, Joshita S, Umemura
T, Matsumoto A, Tanaka E : Cimetidine/lactulose therapy
ameliorates erythropoietic protoporphyria-related liver
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20170060
Genda T, Ichida T, Sakisaka S, Tanaka E,
Mochida S, Ueno Y, Inui A, Egawa H, Umeshita K,
Furukawa H, Kawasaki S, Inomata Y, The Assessment
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20170061
Hanafusa N, Isoai A, Ishihara T, Inoue T,
Ishitani K, Utsugisawa T, Yamaka T, Ito T, Sugiyama H,
Arakawa A, Yamada Y, Itano Y, Onodera H, Kobayashi R,
Torii N, Numata T, Kashiwabara T, Matsuno Y, Kato M :Safety and efficacy of cell-free and concentrated ascites
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2017.
20170062
Harada M, Masubuchi T, Fujii K, Kurasawa Y,
Ichikawa T, Kobayashi M : Modified A-DROP score andmortality in hemodialysis patients with pneumonia. Renal

7

Replacement Therapy 3: 39, 2017.
20170063
Ichikawa Y, Joshita S, Umemura T, Shobugawa
Y, Usami Y, Shibata S, Yamazaki T, Fujimori N, Komatsu
M, Matsumoto A, Tanaka E : Serum Wisteria floribunda
agglutinin-positive human Mac-2 binding protein may
predict liver fibrosis and progression to hepatocellular
carcinoma in patients with chronic hepatitis B virus
infection. Hepatol Res 47: 226-233, 2017.
20170064
Joshita S, Umemura T, Tanaka E, Ota M :Genetic Contribution to the Pathogenesis of Primary Biliary
Cholangitis. J Immunol Res 2017: 3073504, 2017.
20170065
Kawashima M, Hitomi Y, Aiba Y, Nishida N,
Kojima K, Kawai Y, Nakamura H, Tanaka A, Zeniya M,
Hashimoto E, Ohira H, Yamamoto K, Abe M, Nakao K,
Yamagiwa S, Kaneko S, Honda M, Umemura T, Ichida T,
Seike M, Sakisaka S, Harada M, Yokosuka O, Ueno Y, Senju
M, Kanda T, Shibata H, Himoto T, Murata K, Miyake Y,
Ebinuma H, Taniai M, Joshita S, Nikami T, Ota H, Kouno
H, Kouno H, Nakamuta M, Fukushima N, Kohjima M,
Komatsu T, Komeda T, Ohara Y, Muro T, Yamashita T,
Yoshizawa K, Nakamura Y, Shimada M, Hirashima N, Sugi
K, Ario K, Takesaki E, Naganuma A, Mano H, Yamashita
H, Matsushita K, Yamauchi K, Makita F, Nishimura H,
Furuta K, Takahashi N, Kikuchi M, Masaki N, Tanaka T,
Tamura S, Mori A, Yagi S, Shirabe K, Komori A, Migita
K, Ito M, Nagaoka S, Abiru S, Yatsuhashi H, Yasunami M,
Shimoda S, Harada K, Egawa H, Maehara Y, Uemoto S,
Kokudo N, Takikawa H, Ishibashi H, Chayama K, Mizokami
M, Nagasaki M, Tokunaga K, Nakamura M : Genomewide association studies identify PRKCB as a novel genetic
susceptibility locus for primary biliary cholangitis in theJapanese population. Hum Mol Genet 26: 650-659, 2017.
20170066
Kimura T, Kobayashi A, Tanaka N, Sano K,
Komatsu M, Fujimori N, Yamazaki T, Shibata S, Ichikawa
Y, Joshita S, Umemura T, Matsumoto A, Horiuchi A,
Mori H, Wada S, Kiyosawa K, Miyagawa SI, Tanaka
E : Clinicopathological characteristics of non-B non-C
hepatocellular carcinoma without past hepatitis B virus
infection. Hepatol Res 47: 405-418, 2017.
20170067
Kimura T, Shinji A, Tanaka N, Koinuma M,
Yamaura M, Nagaya T, Joshita S, Komatsu M, Umemura T,
Horiuchi A, Wada S, Tanaka E : Association between lower
air pressure and the onset of ischemic colitis: a case-control
study. Eur J Gastroenterol Hepatol 29: 1071-1078, 2017.
20170068
Kitabatake H, Nagaya T, Tanaka N, Ota H,
Sano K, Asano N, Suga T, Nakamura Y, Akamatsu T,
Tanaka E : Development of diffuse large B-cell lymphoma

from follicular lymphoma of the duodenum: changes inendoscopic findings during a 6-year follow-up. Clin J
Gastroenterol 10: 79-85, 2017.
20170069
K i t a b a t a k e H , Ta n a k a N , F u j i m o r i N ,Komatsu M, Okubo A, Kakegawa K, Kimura T, Sugiura A,
Yamazaki T, Shibata S, Ichikawa Y, Joshita S, Umemura T,
Matsumoto A, Koinuma M, Sano K, Aoyama T, Tanaka E :Association between endotoxemia and histological featuresof nonalcoholic fatty liver disease. World J Gastroenterol 23:
712-722, 2017.
20170070
M a t s u m o t o A , I m a i z u m i M , Ta n a k a Y,
Nishiguchi S, Yatsuhashi H, Ishida T, Moriyama K, Aoyagi
K, Tanaka E : Novel and highly sensitive immunoassay for
total hepatitis B surface antigen, including that complexedwith hepatitis B surface antibody. J Gastroenterol 52: 376384, 2017.
20170071
Nakajima T, Yang Y, Lu Y, Kamijo Y, Yamada
Y, Nakamura K, Koyama M, Yamaguchi S, Sugiyama E,
Tanaka N, Aoyama T : Decreased Fatty Acid beta-Oxidation
Is the Main Cause of Fatty Liver Induced by Polyunsaturated
Fatty Acid Deficiency in Mice. Tohoku J Exp Med 242: 229239, 2017.
20170072
Ogawara A, Harada M, Ichikawa T, Fujii K,
Ehara T, Kobayashi M : Coexistence of Anti-Glomerular
Basement Membrane Glomerulonephritis and Membranous
Nephropathy in a Female Patient with Preserved Renal
Function. Tohoku J Exp Med 243: 335-341, 2017.
20170073
Ozawa M, Fujinaga Y, Asano J, Nakamura A,
Watanabe T, Ito T, Muraki T, Hamano H, Kawa S : Clinicalfeatures of IgG4-related periaortitis/periarteritis based on theanalysis of 179 patients with IgG4-related disease: a casecontrol study. Arthritis Res Ther 19: 223, 2017.
20170074
Sekiguchi N, Nishina S, Kawakami T, Sakai H,
Senoo N, Senoo Y, Ito T, Saito H, Nakazawa H, Koizumi T,
Ishida F : Oral cyclophosphamide was effective for Coombsnegative autoimmune hemolytic anemia in CD16+CD56chronic lymphoproliferative disorder of NK-cells. Int J
Hematol 105: 854-858, 2017.
20170075
Sugiura A, Wada S, Mori H, Kimura T, Matsuda
Y, Tanaka N, Tanaka E, Kiyosawa K : Successful Treatment
for Chronic Hepatitis C-Autoimmune Hepatitis Overlap
Syndrome due to Daclatasvir and Asunaprevir. Case Rep
Gastroenterol 11: 305-311, 2017.
20170076
Taida T, Arai M, Kanda T, Hige S, Ueno Y,
Imazeki F, Izumi N, Tanaka E, Shinkai N, Yoshioka K,

8Nakamoto Y, Nishiguchi S, Tsuge M, Abe M, Sata M,
Yatsuhashi H, Ido A, Kita K, Azemoto R, Kitsukawa
Y, Goto N, Yokosuka O : The prognosis of hepatitis B
inactive carriers in Japan: a multicenter prospective study. J
Gastroenterol 52: 113-122, 2017.
20170077
Tanaka N, Takahashi S, Hu X, Lu Y, Fujimori
N, Golla S, Fang ZZ, Aoyama T, Krausz KW, Gonzalez FJ :Growth arrest and DNA damage-inducible 45alpha protects
against nonalcoholic steatohepatitis induced by methionineand choline-deficient diet. Biochim Biophys Acta 1863:
3170-3182, 2017.
20170078
Umemura T, Joshita S, Hamano H, Yoshizawa
K, Kawa S, Tanaka E, Ota M : Association of autoimmune
hepatitis with Src homology 2 adaptor protein 3 gene
polymorphisms in Japanese patients. J Hum Genet 62: 963967, 2017.
20170079
Umemura T, Sekiguchi T, Joshita S, Yamazaki
T, Fujimori N, Shibata S, Ichikawa Y, Komatsu M,
Matsumoto A, Shums Z, Norman GL, Tanaka E, Ota M :Association between serum soluble CD14 and IL-8 levels
and clinical outcome in primary biliary cholangitis. Liver Int
37: 897-905, 2017.
20170080
Yamada Y, Harada M, Yamaguchi A, Kobayashi
Y, Chino T, Minowa T, Kosuge T, Tsukada W, Hashimoto
K, Kamijo Y : Technical Performance and ClinicalEffectiveness of Drop Type With Adjustable ConcentratorCell Free and Concentrated Ascites Reinfusion Therapy.
Artif Organs 41: 1135-1144, 2017.
20170081
Yamada Y, Yamaguchi A, Harada M, Kurasawa
Y, Hara Y, Yamazaki D, Fujita S, Sonoda K, Masuda T,
Yamada A, Ogawa Y, Hashimoto K, Kamijo Y : Protein
Concentration of Refractory Ascites in Cancer Patients is
Reflected by the Presence and Severity of Peritoneal andLiver Metastasis. Ther Apher Dial 21: 263-269, 2017.
20170082
Yamaguchi A, Harada M, Yamada Y, Hashimoto
K, Kamijo Y : Identification of chronic kidney disease
patient characteristics influencing the renoprotective effects
of febuxostat therapy: a retrospective follow-up study. BMC
Nephrol 18: 162, 2017.
20170083
Yamazaki T, Joshita S, Umemura T, Usami Y,
Sugiura A, Fujimori N, Shibata S, Ichikawa Y, Komatsu
M, Matsumoto A, Igarashi K, Tanaka E : Association ofSerum Autotaxin Levels with Liver Fibrosis in Patients with
Chronic Hepatitis C. Sci Rep 7: 46705, 2017.
20170084

Yamazaki T, Ochi Y, Tanaka N, Watanabe

T, Iwaya Y, Seki A, Hara E, Tanaka E, Watanabe T, Imai
S, Hasebe O : Massive ascites caused by intra-pancreatic
arterioportal fistula: a rare complication of chronicpancreatitis. Clin J Gastroenterol 10: 73-78, 2017.
20170085
Ota M, Umemura T, Kawa S : Immunogeneticsof IgG4-Related AIP. In: Okazaki K. IgG4-Related Disease(Current Topics in Microbiology and Immunology. 401).
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Internal Medicine 3
20170086
Doden T, Sekijima Y, Ikeda J, Ozawa K,
Ohashi N, Kodaira M, Hineno A, Tachibana N, Ikeda SI :Postpartum anti-N-methyl-D-aspartate receptor encephalitis:
A case repoty and literature review. Intern Med 56: 357-362,
2017.
20170087
Echigoya Y, Nakamura A, Nagata T, Urasawa
N, Lim KRQ, Trieu N, Panesar D, Kuraoka M, Moulton
HM, Saito T, Aoki Y, Iversen P, Sazani P, Kole R, Maruyama
R, Partridge T, Takeda S, Yokota T : Effects of systemic
multiexon skipping with peptide-conjugated morpholinos in
the heart of a dog model of Duchenne muscular dystrophy.
Proc Natl Acad Sci U S A 18: 4213-4218, 2017.
20170088
Fujita T, Inomata T, Kaida T, Iida Y, Ikeda Y,
Nabeta T, Ishii S, Maekawa E, Naruke T, Koitabashi T,
Kitamura E, Sekijim Y, Ako J : Tafamidis for the treatmentof hereditary transthyretin amyloid cardiomyopathy: A casereport. Cardiology 137: 74-77, 2017.
20170089
Ikeda J, Matsushima A, Ishii W, Goto T,
Takahashi K, Nakamichi K, Saijo M, Sekijima Y, Ikeda SI: Brain biopsy is more reliable than the DNA test for JC
virus in cerebrospinal fluid for the diagnosis of progressive
multifocal leukoencephalopathy. Intern Med 56: 1231-1234,
2017.
20170090
Kano Y, Kodaira M, Ushiki A, Kosaka M,
Yamada M, Shingu K, Nishihara H, Hanaoka M, Sekijima Y: The Complete Remission of Acquired Immunodeficiency
Syndrome-associated Isolated Central Nervous System
Lymphomatoid Granulomatosis: A Case Report and Reviewof the Literature. Intern Med 56: 2497-2501, 2017.
20170091
Katoh N, Ueno A, Yoshida T, Tazawa K,
Shimojima Y, Gono T, Sekijima Y, Matsuda M, Ikeda SI :Bortezomib–dexamethasone versus high-dose melphalan
for Japanese patients with systemic light-chain (AL)amyloidosis: a retrospective single-center study. Int J
Hematol 105: 341-348, 2017.

920170092
Kishida D, Sato M, Kobayashi C, Ueno K,
Kinoshita T, Kodaira M, Shimojima Y, Ishii W, Ushiki
A, Ikeda S : Intractable Cutaneous Nontuberculous
Mycobacteriosis (Mycobacterium abscessus) during
Treatment for Systemic Lupus Erythematosus. Intern Med
56: 1253-1257, 2017.
20170093
K o b a y a s h i Y, S h i m o j i m i a Y, K o n d o Y,
Takamatsu Y, Miyazaki D, Kishida D, Sekijima Y, Ikeda
SI : Protein-losing Gastroenteropathy Related to Mixed
Connective Tissue Disease: A Case Report of a Successful
Outcome and Literature Review. Intern Med 56: 2057-2062,
2017.
20170094
Kodaira M, Kodama S, Kamijo Y, Kaneko T,
Sekijima Y : Muscle training-induced bilateral brachial
plexopathy in an adolescent with sporadic hereditaryneuropathy with liability to pressure palsies. Brain Behav 7:
e00783, 2017.
20170095
Kodaira M, Sekijima Y, Ohashi N, Takahashi Y,
Ueno K, Miyazaki D, Ikeda S : Squatting-induced bilateralperoneal nerve palsy in a sewer pipe worker. Occup Med(Lond) 67: 75-77, 2017.
20170096
Matsushima A, Yoshida K, Genno H, Ikeda SI :Principal component analysis for ataxic gait using a triaxial
accelerometer. J Neuroeng Rehabil 14: 37, 2017.
20170097
Nagamatsu K, Sekijima Y, Nakamura K,
Nakamura K, Hattori K, Ota M, Shimizu Y, Endo F, Ikeda SI: Prevalence of Fabry disease and GLA c.196G>C variant inJapanese stroke patients. J Hum Genet 62: 665-670, 2017.
20170098
Nakamura A : Moving towards successful exonskipping therapy for Duchenne muscular dystrophy. J Hum
Genet 62: 871-876, 2017.
20170099
Nakamura K, Yoshida K, Matsushima A,
Shimizu Y, Sato Yahikozawa H, Ohara S, Yazawa M,
Ushiyama M, Sato M, Morita H, Inoue A, Ikeda SI : Natural
History of Spinocerebellar Ataxia Type 31: a 4-Year
Prospective Study. Cerebellum 16: 518-524, 2017.
20170100
Ogawa Y, Kishida D, Shimojima Y, Hayashi
K, Sekijima Y : Effective Administration of Rituximab
in Anti-MDA5 Antibody-Positive Dermatomyositis with
Rapidly Progressive Interstitial Lung Disease and Refractory
Cutaneous Involvement: A Case Report and Literature
Review. Case Rep Rheumatol 2017: 5386797, 2017.
20170101
Ogawa Y, Nakagawa M, Yoshida T, Yazaki M,
Sekijima S, Hashimoto T, Ikeda SI : Survey of epidemiology,

clinical picture, and current treatments for elderly-onset (＞65) patients with myasthenia gravis in Nagano Prefecture,
Japan. Neurol Clin Neurosci 5: 107-112, 2017.
20170102
Ozawa K, Hineno A, Kinoshita T, Ishihara
S, Ikeda SI : Suspected Adverse Effects After Human
Papillomavirus Vaccination: A Temporal Relationship
Between Vaccine Administration and the Appearance ofSymptoms in Japan. Drug Saf 40: 1219-1229, 2017.
20170103
Oyanagi K, Kinoshita M, Suzuki-Kouyama E,
Inoue T, Nakahara A, Tokiwai M, Arai N, Satoh JI, Aoki
N, Jinnai K, Yazawa I, Arai K, Ishihara K, Kawamura M,
Ishizawa K, Hasegawa K, Yagisita S, Amano N, Yoshida K,
Terada S, Yoshida M, Akiyama H, Mitsuyama Y, Ikeda SI: Adult onset leukoencephalopathy with axonal spheroids
and pigmented glia (ALSP) and Nasu-Hakola disease:lesion staging and dynamic changes of axons and microglial
subsets. Brain Patho 27: 748-769, 2017.
20170104
Sato M, Yazaki M, Miyazaki D, Kishida D,
Nakamura A, Ikeda S : Painful ophthalmoplegia due to
inflammation of the cavernous sinus in a patient withfamilial Mediterranean fever. Modern Rheumatology Case
Reports 1: 58-162, 2017.
20170105
Sato S, Seki H, Ikeda S : Hereditary amyloid
polyneuropathy-related destructive arthropathy in a hip joint.
Amyloid 24: 64-65, 2017.
20170106
Schonhoft JD, Monteiro C, Plate L, Eisele YS,
Kelly JM, Boland D, Parker CG, Cravatt BF, Teruya S,
Helmke S, Maurer M, Berk J, Sekijima Y, Novais M, Coelho
T, Powers ET, Kelly JW : Peptide probes detect misfoldedtransthyretin oligomers in plasma of hereditary amyloidosis
patients. Sci Transl Med 9: eaam7621, 2017.
20170107
Shibata Y, Matsushima M, Yabe I, Matsuda K,
Nagai A, Kano T, Yamada T, Sekijima Y, Sasaki H : Pseudohomozygous mutation due to a primer site polymorphism inhereditary ATTR amyloidosis: a pitfall of PCR-based genetic
testing. Amyloid 24: 66-67, 2017.
20170108
Shimojima Y, Matsuda M, Ishii W, Kishida Dai,
Sekijima Y : T-cell receptor-mediated characteristic signaling
pathway of peripheral blood T cells in dermatomyositis andpolymyositis. Autoimmunity 50: 481-490, 2017.
20170109
Shimojima Y, Ishii W, Kishida D, Fukushima K,
Ikeda SI : Imbalanced expression of dysfunctional regulatory
T cells and T-helper cells relates to immunopathogenesis inpolyarteritis nodosa. Mod Rheumatol 27: 102-109, 2017.

10

20170110
Shimojima Y, Ishii W, Matsuda M, Kishida
D, Ikeda SI : Effective Use of Calcineurin Inhibitor in
Combination Therapy for Interstitial Lung Disease inPatients With Dermatomyositis and Polymyositis. J Clin
Rheumatol 23: 87-93, 2017.
20170111
Shimojima Y, Kishida D, Sekijima Y : Increased
BAFF and APRIL levels in the cerebrospinal fluid ofpatients with anti-neutrophil cytoplasmic antibody-related
hypertrophic pachymeningitis. Cytokine 99: 305-309, 2017.
20170112
Shimojima Y, Kishida D, Hineno A, Yazaki
M, Sekijima Y, Ikeda SI : Hypertrophic pachymeningitis
is a characteristic manifestation of granulomatosis withpolyangiitis: A retrospective study of anti-neutrophil
cytoplasmic antibody-associated vasculitis. Int J Rheum Dis
20: 489-496, 2017.
20170113
Yamaguchi F, Tajika M, Inoue D, Shikama
Y, Kishida D, Nakamura A : Recurrent pleural effusion
is an important diagnostic clue to distinguish familial
Mediterranean fever from Behçet's disease. Clin Exp
Rheumatol 35 suppl. 108: 135, 2017.
20170114
Yoshinaga T, Nakamura K, Ishikawa M,
Yamaguchi T, Takano K, Wakui K, Kosho T, Yoshida K,
Fukushima Y, Sekijima Y : A novel frameshift mutationof SYNE1 in a Japanese family with autosomal recessive
cerebellar ataxia type 8. Hum Genome Var 4: 17052, 2017.
20170115
Yoshinaga T, Yazaki M, Ohno M, Kodama S,
Koyama J, Sekijima Y : Cardiac Amyloidosis AssociatedWith Amyloidogenic Transthyretin V122I Variant in an
Elderly Japanese Woman. Circ J 81: 893-894, 2017.
20170116
Yoshinaga T,Yazaki M, Kametani F, Sekijima
Y,Iesato Y, Miyahara T, Tsuchiya-Suzuki A, Sano K, Higuchi
E, Ikeda S : Marked biochemical difference in amyloid
proportion between intra- and extraocular tissues in a livertransplanted patient with hereditary ATTR amyloidosis.
Amyloid 24: 17-23, 2017.

Internal Medicine 4
20170117
Sekido K, Sekido T, Hosokawa M, Sato A,
Sato Y, Yamazaki M, Komatsu M : Careful readings for a
flash glucose monitoring system in nondiabetic Japanese
subjects: individual differences amd discrepancy in glucose
concentration after glucose loading. Endocr J 64(8): 827832, 2017.

Internal Medicine 520170118
Harada M, Izawa A, Hidaka H, Nakanishi K,
Terasawa F, Motoki H, Yazaki Y, Ikeda U, Hongo M, on
behalf of the Study Project on Prevention of Metabolic
Syndrome among Children, Adolescents, and Young Adultsin Shinshu : Importance of cystatin C and uric acid levels in
the association of cardiometabolic risk factors in Japanese
junior high school students. J Cardiol 69: 222-227, 2017.
20170119Harada M, Miura T, Kobayashi T, Kobayashi
H, Kobayashi M, Nakajima H, Kimura H, Akanuma H,
Mawatari E, Sato T, Hotta S, Kamiyoshi Y, Maruyama
T, Watanabe N, Eisawa T, Hashizume N, Ebisawa S,
Miyashita Y, Ikeda U, On behalf of the SHINANO registry
investigators : Clinical impact of complete revascularizationin elderly patients with multi-vessel coronary artery disease
undergoing percutaneous coronary intervention: A subanalysis of the SHINANO registry. Int J Cardiol 230: 413419, 2017.
20170120
Takeuchi T, Yazaki Y, Okada A, Shimizu K,
Shoin W, Harada M, Minamisawa M, Yoshie K, Oguchi
Y, Motoki H, Koshikawa M, Kasai H, Izawa A, Koyama J,
Shoda M, Ikeda U : Failure of steroid withdrawal guided
by 18F-FDG PET in a patient with cardiac sarcoidosis. J
Cardiol Cases 15: 10-13, 2017.
20170121
Ueki Y, Izawa A, Kashiwagi D, Nishiyama S,
Aso S, Suzuki C, Sakurai S, Oguchi K, Yazaki Y, Ikeda U,
Kuwahara K : Diagnostic advantage of stress computed
tomography myocardial perfusion over single-photon
emission computed tomography for the assessment of
myocardial ischemia. J Cardiol 70: 147-154, 2017.
20170122
Miura T, Miyashita Y, Motoki H, Kobayashi
H, Kobayashi M, Nakajima H, Kimura H, Akanuma H,
Mawatari E, Sato T, Hotta S, Kamiyoshi Y, Maruyama T,
Watanabe N, Eizawa T, Aso S, Uchikawa S, Hashizume N,
Senda K, Morita T, Ebisawa S, Izawa A, Koyama J, Ikeda U: Comparison of mid-term outcomes between patients withand without atrial fibrillation undergoing coronary stenting
in the second-generation drug-eluting stent era: from the
SHINANO registry. Cardiovasc Interv Ther 32: 206-215,
2017.
20170123
Nishimura H, Miura T, Minamisawa M, Ueki Y,
Abe N, Hashizume N, Mochidome T, Harada M, Shimizu K,
Shoin W, Yoshie K, Oguchi Y, Ebisawa S, Motoki H, Izawa
A, Koyama J, Ikeda U : Prognostic value of ankle brachialindex for future incident heart failure in patients without
previous heart failure: data from the impressive predictive

11value of ankle brachial index for clinical long term outcome
in patients with cardiovascular disease examined by ABI
study. Heart Vessels 32: 295-302, 2017.
20170124
Minamisawa M, Miura T, Motoki H, Kobayashi
H, Kobayashi M, Nakajima H, Kimura H, Akanuma H,
Mawatari E, Sato T, Hotta S, Kamiyoshi Y, Maruyama T,
Watanabe N, Eisawa T, Aso S, Uchikawa S, Senda K, Morita
T, Hashizume N, Abe N, Ebisawa S, Izawa A, Miyashita Y,
Koyama J, Ikeda U;On behalf of the SHINANO Registry
Investigators : Prediction of 1-year clinical outcomes using
the SYNTAX score in patients with prior heart failure
undergoing percutaneous coronary intervention: sub-analysisof the SHINANO registry. Heart Vessels 32: 399-407, 2017.
20170125
Ueki Y, Miura T, Minamisawa M, Abe N,
Nishimura H, Hashizume N, Mochidome T, Harada
M, Shimizu K, Oguchi Y, Yoshie K, Shoin W, Ebisawa
S, Motoki H, Koyama J, Ikeda U : The usefulness ofbrachial‑ankle pulse wave velocity in predicting long‑term
cardiovascular events in younger patients. Heart Vessels 32:
660-667, 2017.
20170126
Abe N, Miura T, Miyashita Y, Hashizume N,
Ebisawa S, Motoki H, Tsujimura T, Ishihara T, Uematsu
M, Katagiri T, Ishihara R, Tosaka A, Ikeda U : Long-term
prognostic implications of the admission shock index inpatients with acute myocardial infarction who received
percutaneous coronary intervention. Angiology 68: 339-345,
2017.
20170127
Miura T, Miyashita Y, Motoki H, Kobayashi
H, Kobayashi M, Nakajima H, Kimura H, Akanuma H,
Mawatari E, Sato T, Hotta S, Kamiyoshi Y, Maruyama T,
Watanabe N, Eisawa T, Aso S, Hashizume N, Ebisawa S,
Ikeda U : Efficacy and Safety of Percutaneous Coronary
Intervention for Elderly Patients in the Second-Generation
Drug-Eluting Stent Era: The SHINANO Registry. Angiology
68: 688-697, 2017.
20170128
Ueki Y, Miura T, Miyashita Y, Ebisawa S,
Motoki H, Izawa A, Koyama J, Ikeda U : Inflammatory
Cytokine Levels After Endovascular Therapy in Patients
With Peripheral Artery Disease. Angiology 68: 734-740,
2017.
20170129
Minamisawa M, Miura T, Motoki H, Ueki Y,
Shimizu K, Shoin W, Harada M, Mochidome T, Yoshie K,
Oguchi Y, Hashizume N, Nishimura H, Abe N, Ebisawa
S, Izawa A, Koyama J, Ikeda U : Prognostic Impact ofDiastolic Wall Strain in Patients at Risk for Heart Failure. Int
Heart J 58: 250-256, 2017.

20170130
Nishimura H, Miura T, Minamisawa M, Ueki Y,
Abe N, Hashizume N, Mochidome T, Harada M, Shimizu K,
Shoin W, Yoshie K, Oguchi Y, Ebisawa S, Motoki H, Izawa
A, Koyama J, Ikeda U, Kuwahara K : Ankle-brachial index
for the prognosis of cardiovascular disease in patients withmild renal insufficiency. Intern Med 56: 2103-2111, 2017.
20170131
Yoshinaga T, Yazaki M, Ohno M, Kodama S,
Koyama J, Sekijima Y : Cardiac Amyloidosis AssociatedWith Amyloidogenic Transthyretin V122I Variant in an
Elderly Japanese Woman. Circ J 81: 893-894, 2017.
20170132
Okada A, Shoda M, Takeuchi T, Kato K, Shoin
W, Okano T, Kobayashi H, Oguchi Y, Kuwahara K : Hotballoon ablation of persistent atrial fibrillation with a dilated
left atrium in a case of dilated cardiomyopathy. International
Journal of Diagnostic Imaging 4: 28-30, 2017.
20170133
Okada A, Kashima Y, Tomita T, Takeuchi T,
Oguchi Y, Yoshie K, Shoin W, Shoda M, Nitta K, Kuwahara
K, Imamura H : Cardiac hyaluronan may be associated withthe persistence of atrial fibrillation. Heart Vessels 32: 11441150, 2017.
20170134
Ogasawara T, Okano S, Ichimura H, Kadota S,
Tanaka Y, Minami I, Uesugi M, Wada Y, Saito N, Okada K,
Kuwahara K, Shiba Y : Impact of extracellular matrix onengraftment and maturation of pluripotent stem cell-derived
cardiomyocytes in a rat myocardial infarct model. Sci Rep 7:8630, 2017.
20170135
Miura T, Minamisawa M, Ueki Y, Abe N,
Nishimura H, Hashizume N, Mochidome T, Harada M,
Oguchi Y, Yoshie K, Shoin W, Saigusa T, Ebisawa S, Motoki
H, Koyama J, Ikeda U, Kuwahara K : Impressive predictive
value of ankle-brachial index for very long-term outcomesin patients with cardiovascular disease: IMPACT-ABI study.
PLOS ONE 12: e0177609, 2017.
20170136
Nakagawa Y, Nishikimi T, Kuwahara K,
Fujishima A, Oka S, Tsutamoto T, Kinoshita H, Nakao
K, Cho K, Inazumi H, Okamoto H, Nishida M, Kato T,
Fukushima H, Yamashita JK, Wijnen WJ, Creemers EE,
Kangawa K, Minamino N, Nakao K, Kimura T : MiR30GALNT1/2 Axis-Mediated Glycosylation Contributes tothe Increased Secretion of Inactive Human Prohormone forBrain Natriuretic Peptide (proBNP) From Failing Hearts. J
Am Heart Assoc 6: e003601, 2017.
20170137
Nakao K, Kuwahara K, Nishikimi T, Nakagawa
Y, Kinoshita H, Minami T, Kuwabara Y, Yamada C, Yamada
Y, Tokudome T, Nagai-Okatani C, Minamino N, Nakao YM,
Yasuno S, Ueshima K, Sone M, Kimura T, Kangawa K,

12Nakao K : Endothelium-Derived C-Type Natriuretic Peptide
Contributes to Blood Pressure Regulation by Maintaining
Endothelial Integrity. Hypertension 69: 286-296, 2017.
20170138
Harada E, Mizuno Y, Kugimiya F, Shono
M, Maeda H, Yano N, Kuwahara K, Yasue H : B-Type
Natriuretic Peptide in Heart Failure With Preserved Ejection
Fraction - Relevance to Age-Related Left Ventricular
Modeling in Japanese - . Circ J 81: 1006-1013, 2017.
20170139
Tanabe N, Ikeda S, Tahara N, Fukuda K, Hatano
M, Ito H, Nakayama T, Anzai T, Hashimoto A, Inoue T,
Kajinami K, Kihara Y, Kinoshita H, Kuwahara K, Murohara
T, Okazaki O, Sakai S, Satoh T, Takeda Y, Takeishi Y,
Taniguchi M, Watanabe H, Yamamoto T, YamauchiTakihara K, Yoshioka K, Sasayama S : Efficacy and Safetyof an Orally Administered Selective Prostacyclin Receptor
Agonist, Selexipag, in Japanese Patients With Pulmonary
Arterial Hypertension. Circ J 81: 1360-1367, 2017.
20170140
Saigusa T, Matsuo H, Suzuki T : Angiographical
Changes Induced by Tiny Coronary Fistula. Cardiovasc
Imaging Asia 1: 208-209, 2017.
20170141
Kanzaki Y, Miura T, Hashizume N, Saigusa T,
Ebisawa S, Kuwahara K : Unique angiographic findings ina patient with myocardial ischemia and immunoglobulin
G4-related disease. SAGE Open Med Case Rep 5:2050313X17728010, 2017.
20170142
Hashizume N, Miura T, Miyashita Y, Motoki
H, Ebisawa S, Izawa A, Koyama J, Ikeda U, Kuwahara K;
SHINANO Registry Investigators : Prognostic Value ofAnkle-Brachial Index in Patients Undergoing PercutaneousCoronary Intervention: In-Hospital and 1-Year Outcomes
From the SHINANO Registry. Angiology 68: 884-892,
2017.

20170145
N a k a m u r a T, S u g i y a m a N , H a g i w a r a T,
Sasayama D, Washizuka S : Jitteriness/Anxiety Syndrome
Developing Immediately Following Initiation of Oral
Administration of Sertraline. Case Rep Psychiatry 2017:
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20170146
Ninomiya-Baba M, Matsuo J, Sasayama D, Hori
H, Teraishi T, Ota M, Hattori K, NodaT, Ishida I, Shibata
S, Kunugi H : Association of body mass index-related
single nucleotide polymorphisms with psychiatric disease
and memory performance in a Japanese population. Acta
Neuropsychiatr 29(5): 299-308, 2017.
20170147
Sasayama D, Hattori K, Ogawa S, Yokota Y,
Matsumura R, Teraishi T, Hori H, Ota M, Yoshida S, Kunugi
H : Genome-wide quantitative trait loci mapping of thehuman cerebrospinal fluid proteome. Hum Mol Genet 26(1):44-51, 2017.
20170148
Sasayama D, Kurahashi K, Oda K, Yasaki T,
Yamada Y, Sugiyama N, Inaba Y, Harada Y, Washizuka S,
Honda H : Negative Correlation between Serum Cytokine
Levels and Cognitive Abilities in Children with Autism
Spectrum Disorder. J Intell 5(2): 19, 2017.
20170149
Sasayama D, Sugiyama N, Yonekubo S, Pawlak
A, Murasawa H, Nakamura M, Hayashi M, Ogawa T, Moro
M, Washizuka S, Amano N, Hongo K, Ohnota H : Noveloestrogen receptor β-selective ligand reduces obesity anddepressive-like behaviour in ovariectomized mice. Sci Rep
7: 4663, 2017.
20170150
Suzuki K, Takahashi T, Takahashi K, Uzawa
M, Ohya D, Iizawa M, Takahashi Y, Yasaki T, Sugiyama
N, Washizuka S : Changes over 12 years in the distributionof age, sex, and diagnosis of patients undergoing
electroconvulsive therapy at Shinshu University Hospital.
Psychogeriatrics 17(6): 511-513, 2017.

Psychiatry
20170143
Hidese S, Hattori K, Sasayama D, Miyakawa T,
Matsumura R, Yokota Y, Ishida I, Matsuo J, Noda T, Yoshida
S, Teraishi T, Hori H, Ota M, Kunugi H : Cerebrospinal fluid
neural cell adhesion molecule levels and their correlation
with clinical variables in patients with schizophrenia,
bipolar disorder, and major depressive disorder. Prog
Neuropsychopharmacol Biol Psychiatry 76: 12-18, 2017.
20170144
Ishiwata S, Hattori K, Sasayama D, Teraishi T,
Miyakawa T, Yokota Y, Matsumura R, Yoshida F, Nishikawa
T, Kunugi H : Plasma and cerebrospinal fluid G72 protein
levels in schizophrenia and major depressive disorder.
Psychiatry Res 254: 244-250, 2017.

20170151
Tada H, Ogihara T, Nakamura T, Sasayama D,
Sugiyama N, Takahashi Y, Washizuka S, Amano N : A caseof severe parkinsonism in an elderly person induced byvalproic acid. Psychogeriatrics 17(1): 76-77, 2017.
20170152
Ta k a h a s h i Y, O g i h a r a T, S a s a y a m a D :Successful Readministration of Clozapine in a PatientWith a History of Clozapine-Induced Elevation of Creatine
Phosphokinase. Prim Care Companion CNS Disord 19(4):16l02084, 2017.
20170153
Yoon HS, Hattori K, Ogawa S, Sasayama
D, Ota M, Teraishi T, Kunugi H : Relationships of
Cerebrospinal Fluid Monoamine Metabolite Levels With

13

Clinical Variables in Major Depressive Disorder. J Clin
Psychiatry 78(8): e947-e956, 2017.

Pediatrics
20170154
Motoki N, Akazawa Y, Yamazaki S, Hachiya A,
Motoki H, Matsuzaki S, Koike K : Prognostic Significanceof QT Interval Dispersion in the Response to Intravenous
Immunoglobulin Therapy in Kawasaki Disease. Circ J 81:
537-542, 2017.
20170155
Watanabe T, Kurata T, Sano K, Suzuki S,
Kaneko T, Motobayashi M, Shigemura T, Sumi T, Koike K,
Nakazawa Y : Dramatic Reduction in Tumor Size During
5 Months of Pazopanib Therapy in Combination With
Ifosfamide, Carboplatin, and Etoposide in an Early InfantWith Progressive Soft Tissue Sarcoma. J Pediatr Hematol
Oncol 39: 154-156, 2017.
20170156
Nakayama Y, Lin Y, Hongo M, Hidaka H,
Kikuchi S : Helicobacter pylori infection and its related
factors in junior high school students in Nagano Prefecture,
Japan. Helicobacter 22: e12363, 2017.
20170157
Motobayashi M, Nishimura T, Nakazawa Y,
Inaba Y : Analysis of Serum Cytokine Profiles in ChildhoodOnset Ocular Myasthenia Gravis. Pediatr Neurol 69: e3-e4,
2017.
20170158
Tanaka M, Kamata T, Yanagisawa R, Morita
D, Saito S, Sakashita K, Shiohara M, Kurita H, Koike
K, Nakazawa Y : Increasing Risk of Disturbed RootDevelopment in Permanent Teeth in Childhood Cancer
Survivors Undergoing Cancer Treatment at Older Age. J
Pediatr Hematol Oncol 39: e150-e154, 2017.
20170159
Takeuchi Y, Shigemura T, Kobayashi N,
Kaneko N, Iwasaki T, Minami K, Kobayashi K, Masumoto
J, Agematsu K : Early diagnosis of early-onset sarcoidosis:
a case report with functional analysis and review of theliterature. Clin Rheumatol 36: 1189-1196, 2017.
20170160
Motobayashi M, Fukuyama T, Okuno-Yuguchi
J, Shioiri T, Nagaharu S, Hagimoto R,Kinoshita T, Inaba Y :An Increase of Cerebrospinal Fluid B-cell Activating Factor
Level in Pediatric Patients With Acute Viral Encephalitis.
Pediatr Neurol 70: e3-e4, 2017.
20170161
Kurata T, Shigemura T, Muramatsu H, Okuno
Y, Nakazawa Y : A case of GATA2-related myelodysplastic
syndrome with unbalanced translocation der(1;7)(q10;p10).
Pediatr Blood Cancer 64: e26419, 2017.

20170162
Kanai A, Morokawa H, Matsuda K, Shimazaki
E, Nakazawa Y : Efficacy and safety of anagrelide inchildhood essential thrombocythemia. Pediatr Int 59: 10171018, 2017.
20170163
Motobayashi M, Fukuyama T, Okuno-Yuguchi
J, Tsukahara K, Nagaharu S, Hagimoto R, Kinoshita T,
Nakazawa Y, Inaba Y : Subclinical Neuroaxonal Damage in
Patients With Clinically Mild Encephalitis/Encephalopathy
With a Reversible Splenial Lesion. Pediatr Neurol 74: e3-e4,
2017.
20170164
S higemura T, M oto bayas hi M , Matsuda
K, Shimodaira T, Kurata T, Kobayashi N, Agematsu K,
Nakazawa Y : Acute Myeloid Leukemia in a Patient With
X-linked Severe Combined Immunodeficiency. J Pediatr
Hematol Oncol 39: e470-e472, 2017.
20170165
Motoki N, Akazawa Y, Hachiya A, Inaba
Y : Sudden improvement in ventricular repolarization
abnormality after a short detraining period in an athlete.
Cardiol Young 27: 1849-1852, 2017.
20170166
Morikawa M, Takano K, Motobayashi M, Shiba
N, Kosho T, Nakazawa Y, Inaba Y : Clinical features ofa female with WDR45 mutation complicated by infantile
spasms: a case report and literature review. Brain Dev 39:
804-807, 2017.
20170167
Yanagisawa R, Ogiso Y, Yoshikawa K, Tanaka
M, Matsuda K, Ishii E : Myelomonocytic differentiation
associated with NPM1-RARA rearrangement. Br J Haematol
179: 183, 2017.
20170168
Yanagisawa R, Abe S, Fujihara I, Komori K,
Kondo Y, Sakashita K, Nakamura T : Transfusion-associatedhypoxemia in pediatric patients with solid tumors after
autologous peripheral blood stem cell transplantation.
Transfus Apher Sci 56: 744-747, 2017.
20170169
Ya n a g i s a w a R , Ta k e u c h i K , K o m o r i K ,Fujihara I, Hidaka Y, Morita D, Futatsugi A, Ono T, Hidaka
E, Sakashita K, Shiohara M : Hypoglycemia During the
Temporary Interruption of Parenteral Nutrition Infusion in
Pediatric Hematopoietic Stem Cell Transplantation. JPEN J
Parenter Enteral Nutr 41: 1414-1418, 2017.
20170170
Al-Kzayer LFY, Sarsam SN, Alhur NY, Liu T,
Nakazawa Y : Asymmetrically enlarged parietal foramina
in a rare case of Goldenhar syndrome with a possible
etiopathogenesis. Oncotarget 9: 2962-2968, 2017.
20170171

Liu T, Al-Kzayer LFY, Xie X, Fan H, Sarsam

14SN, Nakazawa Y, Chen L : Mediastinal lesions across theage spectrum: a clinicopathological comparison between
pediatric and adult patients. Oncotarget 8: 59845-59853,
2017.
20170172
Suzuki K, Suzuki Y, Hama A, Muramatsu H,
Nakatochi M, Gunji M, Ichikawa D, Hamada M, Taniguchi
R, Kataoka S, Murakami N, Kojima D, Sekiya Y, Nishikawa
E, Kawashima N, Narita A, Nishio N, Nakazawa Y, Iwafuchi
H, Watanabe KI, Takahashi Y, Ito M, Kojima S, Kato
S, Okuno Y : Recurrent MYB rearrangement in blastic
plasmacytoid dendritic cell neoplasm. Leukemia 31: 16291633, 2017.
20170173
Hirabayashi K, Takatsuki M, Motobayashi M,
Kurata T, Saito S, Shigemura T, Nakazawa Y, Sakashita
K, Ishizone S, Ota H, Koike K : Nonocclusive mesentericischemia after chemotherapy in an adolescent patientwith a history of three allogeneic hematopoietic stem celltransplantations for acute lymphoblastic leukemia. Pediatr
Neonatol 58: 81-84, 2017.
20170174
Chen L, Al-Kzayer LF, Liu T, Kobayashi N,
Nakazawa Y, Koike K : IFR4/MUM1-positive lymphoma in
Waldeyer ring with co-expression of CD5 and CD10. Pediatr
Blood Cancer 64: 311-314, 2017.
20170175
Ono S, Okano T, Hoshino A, Yanagimachi M,
Hamamoto K, Nakazawa Y, Imamura T, Onuma M, Niizuma
H, Sasahara Y, Tsujimoto H, Wada T, Kunisaki R, Takagi
M, Imai K, Morio T, Kanegane H : Hematopoietic stem
cell transplantation for XIAP deficiency in Japan. J Clin
Immunol 37: 85-91, 2017.
20170176
Kanamitsu K, Shimada A, Nishiuchi R,
Shigemura T, Nakazawa Y, Koike K, Kodama Y, Shinkoda
Y, Kawano Y, Yasui K, Sasaki K, Kajiwara R, Tsukahara H,
Manabe A : Pediatric intestinal Behçet disease complicatedby myeloid malignancies. Int J Hematol 105: 377-382, 2017.
20170177
U y e n T N , S a k a s h i t a K , A l - K z a y e r L F,
Nakazawa Y, Kurata T, Koike K : Aberrant methylation of
protocadherin 17 and its prognostic value in pediatric acutelymphoblastic leukemia. Pediatr Blood Cancer 64: e26259,
2017.
20170178
I c h i m a t a S , Yo s h i z a w a A , K u s a k a r i M ,Nakayama Y, Asaka S, Negishi T, Kasuga E, Matsumoto
T, Honda T : Human intestinal spirochetosis in Japanesepatients aged less than 20 years: Histological analysis ofcolorectal biopsy and surgical specimens obtained from 479
patients. Pathol Int 67: 302-305, 2017.

20170179
Uedo N, Yoshio T, Yoshinaga S, Takeuchi M,
Hatta W, Yano T, Tanuma T, Goto O, Takahashi A, Tong D,
Lee YY, Nakayama Y, Ichihara S, Gotoda T : Endoscopic
gastric mucosal atrophy distinguishes the characteristics ofsuperficial esophagogastric junction adenocarcinoma. Dig
Endosc 29 (Suppl 2): 26-36, 2017.
20170180
Nakayama Y, Ida S : Endoscopic findings ofesophagogastric junction in children. Dig Endosc 29 (Suppl2): 11-17, 2017.
20170181
Hoshino A, Okada S, Yoshida K, Nishida
N, Okuno Y, Ueno H, Yamashita M, Okano T, Tsumura
M, Nishimura S, Sakata S, Kobayashi M, Nakamura H,
Kamizono J, Mitsui-Sekinaka K, Ichimura T, Ohga S,
Nakazawa Y, Takagi M, Imai K, Shiraishi Y, Chiba K,
Tanaka H, Miyano S, Ogawa S, Kojima S, Nonoyama S,
Morio T, Hirokazu Kanegane H : Abnormal hematopoiesis
and autoimmunity in humans with germline IKZF1
mutations. J Allergy Clin Immunol 140: 223-231, 2107.
20170182
Akazawa Y, Kamiya M, Yamazaki S, Kawasaki
Y, Nakamura C, Takeuchi Y, Hachiya A, Kusakari M,
Miyosawa Y, Motoki N, Koike K, Nakamura T : Impact ofDecreased Serum Insulin-Like Growth Factor-1 Levels on
Central Aortic Compliance in Small-for-Gestational-Age
Infants. Naonatology 111: 30-36, 2017.
20170183
Morita D, Nishio N, Saito S, Tanaka M,
Kawashima N, Okuno Y, Suzuki S, Matsuda K, Maeda Y,
Wilson MH, Dotti G, Rooney CM, Takahashi Y, Nakazawa
Y : Enhanced expression of anti-CD19 chimeric antigen
receptor in piggyBac transposon-engineered T cells. Mol
Ther Methods Clin Dev 8: 131-140, 2017.

Dermatology
20170184
Hidaka T, Ogawa E, Kobayashi EH, Suzuki T,
Funayama R, Nagashima T, Fujimura T, Aiba S, Nakayama
K, Okuyama R, Yamamoto M : The aryl hydrocarbon
receptor AhR links atopic dermatitis and air pollution via
induction of the neurotrophic factor artemin. Nat Immunol
18: 64-73, 2017.
20170185
Sakaizawa K, Ashida A, Uhara H, Okuyama
R : Detection of BRAFV600K mutant tumor-derived
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20170186
Sato Y, Kato H, Ebina-Shibuya R, Itoh-Nakadai
A, Okuyama R, Igarashi K : Bach2 Controls Homeostasis of
Eosinophils by Restricting the Type-2 Helper Function of T
Cells. Tohoku J Exp Med 241: 175-182, 2017.

15

20170187
Miyake T, Kiniwa Y, Kosho T, Nakano H,
Okuyama R : Hypohidrotic ectodermal dysplasia: A report oftwo cases. J Dermatol 44: 479-481, 2017.
20170188
Tsuji A, Kiniwa Y, Kamijo F, Miyake T, Ohashi
A, Senoo N, Urushihata K, Okuyama R : Polyarteritis
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203-204, 2017.
20170189
Koga H : Dermoscopic evaluation ofmelanonychia. J Dermatol 44: 515-517, 2017.
20170190
Minagawa A : Dermoscopy-pathology
relationship in seborrheic keratosis. J Dermatol 44: 518-524,
2017.
20170191
K u m a g a i Y, U m e g a k i - A r a o N , S a s a k i
T, Nakamura Y, Takahashi H, Ashida A, Tsunemi Y,
Kawashima M, Shimizu A, Ishiko A, Nakamura K,
Tsuchihashi H, Amagai M, Kubo A : Distinct phenotype
of epidermolysis bullosa simplex with infantile migratory
circinate erythema due to frameshift mutations in theV2 domain of KRT5. J Eur Acad Dermatol Venereol 31:
e241-e243, 2017.
20170192
Yamamoto T, Ohtsuki M, Sano S, Igarashi A,
Morita A, Okuyama R, Kawada A : Prevalence and current
therapies of psoriatic arthritis in Japan: A survey by theJapanese Society of Psoriasis Research in 2016. J Dermatol
44: e121, 2017.

20170196
Minagawa A, Omodaka T, Koga H, Yokokawa
Y, Uhara H, Okuyama R : Nail apparatus melanoma
thickness is associated with side and age. Br J Dermatol 177:
e65-e66, 2017.
20170197
Takeichi T, Kobayashi A, Ogawa E, Okuno Y,
Kataoka S, Kono M, Sugiura K, Okuyama R, Akiyama M :Autosomal dominant familial generalized pustular psoriasis
caused by a CARD14 mutation. Br J Dermatol 177:e133-e135, 2017.
20170198
Ogawa Y, Kishida D, Shimojima Y, Hayashi
K, Sekijima Y : Effective Administration of Rituximab
in Anti-MDA5 Antibody-Positive Dermatomyositis with
Rapidly Progressive Interstitial Lung Disease and Refractory
Cutaneous Involvement: A Case Report and Literature
Review. Case Rep Rheumatol 2017: 5386797, 2017.
20170199
Ashida A, Sakaizawa K, Uhara H, Okuyama
R : Circulating Tumour DNA for Monitoring Treatment
Response to Anti-PD-1 Immunotherapy in Melanoma
Patients. Acta Derm Venereol 97: 1212-1218, 2017.
20170200
Sano K, Asahina M, Uehara T, Matsumoto K,
Araki N, Okuyama R : Degranulation and shrinkage of darkcells in eccrine glands and elevated serum carcinoembryonicantigen in patients with acquired idiopathic generalized
anhidrosis. J Eur Acad Dermatol Venereol 31: 2097-2103,
2017.

Radiology
20170193
Shirai T, Kiniwa Y, Asaka S, Shimojo Y,
Kamijo F, Okuyama R : Expression of Mucin 1 in Mycosis
Fungoides Tumour Cells: A Case Report. Acta Derm
Venereol 97: 747-748, 2017.
20170194
Mikoshiba Y, Minagawa A, Sano T, Okuyama R: Pink nodule accompanied with clustered yellow globules atthe periphery. JAAD Case Rep 3: 351-353, 2017.
20170195
Watanabe S, Ohnishi T, Yuasa A, Kiyota H,
Iwata S, Kaku M, Watanabe A, Sato J, Hanaki H, Manabe
M, Suzuki T, Otsuka F, Aihara M, Iozumi K, Tamaki T,
Funada Y, Shinozaki M, Kobayashi M, Okuda M, Kikyo G,
Kikuchi K, Okada Y, Takeshima M, Kaneko O, Ogawa N,
Ito R, Okuyama R, Shimada S, Shimizu T, Hatta N, Manabu
M, Tsutsui K, Tanaka T, Miyachi Y, Asada H, Furukawa
F, Kurokawa I, Iwatsuki K, Hide M, Muto M, Yamamoto
O, Niihara H, Takagaki K, Kubota Y, Sayama K, Sano S,
Furue M, Kanekura T : The first nationwide surveillance ofantibacterial susceptibility patterns of pathogens isolated
from skin and soft-tissue infections in dermatology
departments in Japan. J Infect Chemother 23: 503-511, 2017.

20170201
Yamada A, Komatsu D, Suzuki T, Kurozumi M,
Fujinaga Y, Ueda K, Kadoya M : Evaluation of user input
methods for manipulating a tablet personal computer insterile techniques. Int J Comput Assist Radiol Surg 12: 339349, 2017.
20170202
Yanagisawa S, Fujinaga Y, Watanabe T,
Maruyama M, Muraki T, Takahashi M, Fujita A, Fujita
S, Kurozumi M, Ueda K, Hamano H, Kawa S, Kadoya
M : Usefulness of three-dimensional magnetic resonancecholangiopancreatography with partial maximum intensity
projection for diagnosing autoimmune pancreatitis.
Pancreatology 17: 567-571, 2017.
20170203
Yoshizawa E, Koiwai K, Ina H, Fukazawa A,
Sakai K, Ozawa T, Matsushita H, Kadoya M : Outcomesof uterine cervical cancer patients with pelvic lymph nodemetastases after radiotherapy without boost irradiation ofmetastases. J Obstet Gynecol Res 43: 718-722, 2017.
20170204

Ozawa T, Koiwai K, Matsushita H, Kadoya

16

M : Dosimetric comparisons of Volumetric modulated arc
therapy with three-dimensional conformal radiation therapy
for locally advance non-small cell lung cancer. Shinshu Med
J 65: 93-98, 2017.
20170205
Ohya A, Higuchi K, Shimojo H, Fujinaga Y,
Kadoya M, Shiohara S : Epithelioid trophoblastic tumorof the uterus: a case report with radiologic-pathologic
correlation. J Obstet Gynecol Res 43: 1360-1365, 2017.
20170206
Ohya A, Yamanoi K, Shimojo H, Fujii C,
Nakayama J : Gastric gland mucin-specific O-glycan
expression decreases with tumor progression from precursor
lesions to pancreatic cancer. Cancer Sci 108: 1897-1902,
2017.

Surgery 1
20170207
N o t a k e T, K o b a y a s h i A , S h i n k a w a H ,Kawahara T, Shimizu A, Yokoyama T, Hasegawa K,
Kokudo N, Matsuyama Y, Makuuchi M, Miyagawa SI :Nomogram predicting long-term survival after the diagnosis
of intrahepatic recurrence of hepatocellular carcinoma
following an initial liver resection. Int J Clin Oncol 22: 715725, 2017.
20170208
Motoyama H, Kobayashi A, Yokoyama T,
Shimizu A, Kitagawa N, Notake T, Fukushima K, Masuo
H, Yoshizawa T, Miyagawa SI : Survival Benefits ofSurgical Resection in Patients with Recurrent Biliary Tract
Carcinoma. World J Surg 41: 2817-2829, 2017.
20170209
Kitagawa N, Motoyama H, Kobayashi A,
Yokoyama T, Shimizu A, Notake T, Fukushima K, Masuo
H, Yoshizawa T, Tsukahara T, Miyagawa SI : Adjuvant
Chemotherapy with Gemcitabine for Resected Biliary Tract
Cancer: A Single-Arm Phase II Study. Shinshu Med J 65:
99-111, 2017.
20170210
Imai S, Suzuki A, Yamamoto Y, Koyama M,
Sugiyama S, Kitazawa M, Miyagawa Y, Miyagawa S :Primary malignant melanoma of esophagus following
chemoradiotherapy for esophageal squamous cell carcinoma:
report of a case. Clin J Gastroenterol 10: 336-341, 2017.
20170211
Yamamoto Y, Miyagawa Y, Ehara T, Koyama
M, Nakamura S, Takeuchi D, Muranaka F, Kitazawa M,
Miyagawa S : Three Cases of Pseudo-Meigs' Syndrome
Secondary to Ovarian Metastases from Colorectal Cancer.
Case Rep Surg 2017: 5235368, 2017.
20170212
K o y a m a M , M i y a g a w a Y, Ya m a m o t o Y,
Kitazawa M, Suzuki A, Ishizone S, Miyagawa S : Surgery

for chronic mesh infection occurred 10 years aftersacrectomy - Mesh resection and mesentric leaf repair: A
case report. Int J Surg Case Rep 30: 215-217, 2017.
20170213
Kitazawa M, Hida S, Fujii C, Taniguchi S,
Ito K, Matsumura T, Okada N, Sakaizawa T, Kobayashi
A, Takeoka M, Miyagawa SI : ASC Induces Apoptosis
via Activation of Caspase-9 by Enhancing Gap JunctionMediated Intercellular Communication. PLoS One 12:
e0169340, 2017.

Surgery 2
20170214
Gomibuchi T, Seto T, Yamamoto T, Nakahara
K, Ohashi N, Ohtsu Y, Wada Y, Fukui D, Okada K : Surgicalrepair of cervical aortic arch with brain circulation anomaly
through clamshell incision. Ann Thorac Surg 104(3):e235-e237, 2017.
20170215
Ichimura H, Shiba Y : Recent progress using
pluripotent stem cells for cardiac regenerative therapy. Circ J
81: 929-935, 2017.
20170216
Shibata T, Watari K, Izumi H, Kawahara A,
Hattori S, Fukumitsu C, Murakami Y, Takahashi R, Toh U,
Ito K, Ohdo S, Tanaka M, Kage M, Kuwano M, Ono M :Breast cancer resistance to antiestrogens is enhanced byincreased ER degradation and ERBB2 expression. Cancer
Res 77: 545-556, 2017.
20170217
Ito Y, Onoda N, Ito K, Sugitani I, Takahashi S,
Yamaguchi I, Kabu K, Tsukada K : Sorafenib in JapanesePatients with Locally Advanced or Metastatic Medullary
Thyroid Carcinoma and Anaplastic Thyroid Carcinoma.
Thyroid 27(9): 1142-1148, 2017.
20170218
Iesato A, Nakamura T, Izumi H, Uehara T, Ito
K : PATZ1 knockdown enhances malignant phenotype inthyroid epithelial follicular cells and thyroid cancer cells.
Oncotarget 8(47): 82754-82772, 2017.
20170219
Iesato A, Oba T, Ono K, Watanabe T, Ito T,
Kanai T, Maeno K, Ito K : Case of painless thyroiditis thatdeveloped during adjuvant chemotherapy for breast cancer.
International Cancer Conference Journal 6(4): 184-187,
2017.
20170220
Oba T, Maeno K, Ono M, Iesato A, Ito T,
Kanai T, Mochizuki Y, Ito K, Yoshizawa A, Takayama F : A
case of adenomyoepithelioma of the breast showing strong
uptake of 18F-fluorodeoxyglucose on a positoron emission
tomography. Breast J 23(2): 220-224, 2017.

1720170221
Shiina T, Saito G, Sakaizawa T, Agatsuma
H, Tominaga Y, Hyogotani A, Hamanaka K, Toishi M,
Takasuna K, Kondo R, Yoshida K, Ito K : Higher Tissue
Levels of Thymidylate Synthase Determined by ELISAAre Associated with Poor Prognosis of Patients with Lung
Cancer. Tohoku J Exp Med 242(2): 303-316, 2017.
20170222
Agatsuma H, Yoshida K, Yoshino I, Okumura
M, Higashiyama M, Suzuki K, Tsuchida M, Usuda J, Niwa
H : Video-Assisted Thorscic Surgery Thymectomy Versus
Sternotmy Thymectomy in Patients With Thymoma. Ann
Thorac Surg 104(3): 1047-1053, 2017.
20170223
Miura K, Hamanaka K, Koizumi T, Kitaguchi
Y, Terada Y, Nakamura D, Kumeda H, Agatsuma H,
Hyogotani A, Kawakami S, Yoshizawa A, Asaka S, Ito K :Clinical significance of preoperative serum albumin levelfor prognosis in surgically resected patients with non-small
cell lung cancer-comprehensive study with normal lung,emphysema and pulmonary fibrosis. Lung cancer 111: 88-95,
2017.
20170224
Nakamura D, Miura K, Kumeda H, Agatsuma
H, Hyogotani A, Hamanaka K, Koizumi T, Yamamoto H,
Tamada H, Ito K : Successful resection of G719X positive
pleomorphic carcinoma after afatinib treatment. Case Rep
Oncol 10(3): 1035-1040, 2017.

Orthopaedic Surgery
20170225
Komatsu M, Kamimura M, Nakamura Y,
Mukaiyama K, Ikegami S, Hayashi M, Uchiyama S,
Kato H : Bony findings detected by MRI may reflect
the pathophysiology of osteoarthritis with thumbcarpometacarpal joint pain. Int J Rheum Dis 20: 1950-1957,2017.
20170226
K a m i m u r a M , N a k a m u r a Y, I k e g a m i S ,Uchiyama S, Kato H, Taguchi A : Significant improvementof bone mineral density and bone turnover markers bydenosumab therapy in bisphosphonate-unresponsive
patients. Osteoporos Int 28: 559-566, 2017.
20170227
S o p h o n n i t h i p r a s e r t T, M a h a b u s a r a k a m
W, Nakamura Y, Watanapokasin R : Goniothalamininduces mitochondria-mediated apoptosis associated withendoplasmic reticulum stress-induced activation of JNK in
HeLa cells. Oncol Lett 13: 119-128, 2017.
20170228
Ideta H, Uchiyama S, Hayashi M, Kosho T,
Nakamura Y, Kato H : Painful locking of the wrist in apatient with pseudoachondroplasia confirmed by COMP
mutation. J Surg Case Rep 2017: rjw216, 2017.

20170229
Tanaka M, Nakamura Y, Itoh S, Kato Y :Comparison of effectiveness and safety of ibandronate
and minodronate combined with eldecalcitol in primaryosteoporosis of women: A 1-year follow-up study.
Osteoporos Sarcopenia 3: 37-44, 2017.
20170230
Kamimura M, Uchiyama S, Nakamura
Y, Ikegami S, Mukaiyama K, Kato H : Short-termbisphosphonate treatment reduces serum 25(OH) vitamin D3
and alters values of parathyroid hormone, pentosidine, andbone metabolic markers. Ther Clin Risk Manag 13: 161-168,
2017.
20170231
Nakamura Y, Suzuki T, Yoshida T, Yamazaki
H, Kato H : Vitamin D and Calcium Are Required during
Denosumab Treatment in Osteoporosis with Rheumatoid
Arthritis. Nutrients 9: E428, 2017.
20170232
Nakamura Y, Suzuki T, Kamimura M, Ikegami
S, Uchiyama S, Kato H : Alfacalcidol increases thetherapeutic efficacy of ibandronate on bone mineral density
in Japanese women with primary osteoporosis. Tohoku J Exp
Med 241: 319-326, 2017.
20170233
Nakamura Y, Suzuki T, Kamimura M, Ikegami
S, Mukaiyama K, Uchiyama S, Taguchi A, Kato H : Twoyear clinical outcome of denosumab treatment alone and incombination with teriparatide in Japanese treatment-naive
postmenopausal osteoporotic women. Bone Res 5: 16055,
2017.
20170234
Murakami K, Kobayashi Y, Uehara S, Suzuki
T, Koide M, Yamashita T, Nakamura M, Takahashi N, Kato
H, Udagawa N, Nakamura Y : A Jak1/2 inhibitor, baricitinib,
inhibits osteoclastogenesis by suppressing RANKL
expression in osteoblasts in vitro. PLoS One 12: e0181126.,2017.
20170235
Suzuki T, Nakamura Y, Kamimura M, Ikegami
S, Uchiyama S, Kato H : Compliance and discontinuation ofdenosumab treatment in postmenopausal Japanese womenwith primary osteoporosis or rheumatoid arthritis andosteoporosis. Osteoporos Sarcopenia 3: 108-111, 2017.
20170236
Nakamura Y, Uchiyama S, Kamimura M,
Ikegami S, Komatsu M, Kato H : Increased Serum 25(OH)
D3 Levels in Post-Menopausal Japanese Women with
Osteoporosis after 3-Year Bisphosphonate Treatment.
Tohoku J Exp Med 242: 241-246, 2017.
20170237
Nakamura Y, Suzuki T, Kato H : Serumbone alkaline phosphatase is a useful marker to evaluate
lumbar bone mineral density in Japanese post-menopausal

18

osteoporotic women during denosumab treatment. Ther Clin
Risk Manag 13: 1343-1348, 2017.
20170238
Suzuki T, Nakamura Y, Kato H : Changes ofbone-related minerals during denosumab administratoin in
post-menopausal osteoporotic patients. Nutrients 9: E871,
2017.
20170239
Nakamura Y, Suzuki T, Kato H : Denosumab
significantly improves bone mineral density with orwithout bisphosphonate pre-treatment in osteoporosis withrheumatoid arthritis. Arch Osteoporos 12: 80, 2017.
20170240
Nakamura Y, Suzuki T, Kamimura M, Ikegami
S, Mukaiyama K, Uchiyama S, Taguchi A, Kato H : Vitamin
D and calcium are required at the time of denosumab
administration during osteoporosis treatment. Bone Res 5:17021, 2017.
20170241
Okamoto M, Yoshimura Y, Aoki K, Kito M,
Tanaka A, Suzuki S, Takazawa A, Isobe K, Kato H : Clinicaloutcomes of patients 80 years of age and older with soft
tissue sarcoma. J Orthop Sci 22: 951-957, 2017.
20170242
Okamoto M, Takazawa A, Aoki K, Yoshimura
Y, Kato H, Otsuki T, Maeno K, Koizumi T : Initial clinicalpresentation of single soft tissue metastasis of medullary
thyroid carcinoma without primary tumor in the thyroid
gland. World J Surg Oncol 15: 221, 2017.
20170243
Okamoto M, Yamazaki H, Yoshimura Y, Aoki
K, Tanaka A, Kato H, : Massive trapezial metastasis fromgastric adenocarcinoma resected and reconstructed with avascularized scapular bone graft: A case report. Medicine(Baltimore) 96: e9294, 2017.
20170244
Uehara M, Takahashi J, Ikegami S, Hashidate
H, Kuraishi S, Shimizu M, Futatsugi T, Oba H, Mukaiyama
K, Ogihara N, Hirabayashi H, Kato H : Optimal cervicalscrew insertion angle determined by means of computed
tomography scans pre- and postoperatively. Spine J 17: 190195, 2017.
20170245
Uehara M, Takahashi J, Ikegami S, Kuraishi
S, Shimizu M, Futatsugi T, Oba H, Kato H : Are pedicle
screw perforation rates influenced by the distance from thereference frame in multi-level registration using CT-basednavigation system in the setting of scoliosis?. Spine J 17:
499-504, 2017.
20170246
Uehara M, Takahashi J, Kuraishi S, Shimizu
M, Ikegami S, Futatsugi T, Oba H, Kato H : Computerassisted skip pedicle screw fixation for adolescent idiopathic

scoliosis. J Orthop Sci 22: 218-223, 2017.
20170247
Uehara M, Nakamura Y, Takahashi J, Kamimura
M, Ikegami S, Suzuki T, Uchiyama S, Yamaguchi T, Kosho
T, Kato H : Efficacy of Denosumab for Osteoporosis in
Three Female Patients with Osteogenesis Imperfecta.
Tohoku J Exp Med 242: 115-120, 2017.
20170248
Uehara M, Takahashi J, Ikegami S, Kuraishi
S, Futatsugi T, Kato H : Screw perforation rates in 359
consecutive patients receiving computer-guided pedicle
screw insertion along the cervical to lumbar spine. Eur Spine
J 26: 2858-2864, 2017.
20170249
Uehara M, Takahashi J, Ikegami S, Kuraishi
S, Shimizu M, Futatsugi T, Oba H, Koseki M, Kato H :Pedicle Screw Loosening after Posterior Spinal Fusion
for Adolescent Idiopathic Scoliosis in Upper and Lower
Instrumented Vertebrae Having Major Perforation. Spine 42:
1895-1900, 2017.
20170250
Tanaka A, Yoshimura Y, Ishida T, Aoki K,
Okamoto M, Kito M, Suzuki S, Takazawa T, Kato H :Prediction of muscle strength and postoperative function
after knee flexor muscle resection for soft tissue sarcomaof the lower limbs. Orthop Traumatol Surg Res 103: 10811085, 2017.
20170251
Shimodaira H, Tensho K, Akaoka Y, Takanashi
S, Kato H, Saito N : Tibial tunnel positioning techniqueusing bony/anatomical landmarks in anatomical anterior
cruciate ligament reconstruction. Arthrosc Tech 6: e49-e55,
2017.
20170252
Yamazaki H, Shinone M, Kato H : Compressive
Ulnar Neuropathy Caused by Olecranon Bursitis andConcomitant Epidermal Cyst: A Case Report. J Hand Surg
Asian Pac Vol 22: 503-507, 2017.
20170253
Mimura T, Uchiyama S, Hayashi M, Uemura K,
Moriya H, Kato H : Flexor carpi radialis brevis muscle: Acase report and its prevalence in patients with carpal tunnel
syndrome. J Orthop Sci 26: 1026-1030, 2017.
20170254
Tanaka M, Sato Y, Haniu H, Nomura H,
Kobayashi S, Takanashi S, Okamoto M, Takizawa T, Aoki
K, Usui Y, Oishi A, Kato H, Saito N : A three-dimensional
block structure consisting exclusively of carbon nanotubes
serving as bone regeneration scaffold and as bone defectfiller. PLoS One 12: e0172601, 2017.
20170255
Tanaka M, Sato Y, Zhang M, Haniu H, Okamoto
M, Aoki K, Takizawa T, Yoshida K, Sobajima A, Kamanaka

19

T, Kato H, Saito N : In Vitro and In Vivo Evaluation of aThree-Dimensional Porous Multi-Walled Carbon Nanotube
Scaffold for Bone Regeneration. Nanomaterials (Basel) 7:
46, 2017.
20170256
Tanaka M, Haniu H, Kamanaka T, Takizawa T,
Sobajima A, Yoshida K, Aoki K, Okamoto M, Kato H, Saito
N : Physico-Chemical, In Vitro, and In Vivo Evaluation of a
3D Unidirectional Porous Hydroxyapatite Scaffold for BoneRegeneration. Materials (Basel) 10: 33, 2017.
20170257
Ohi H, Uchiyama S, Kanda T, Mukoda M,
Hayashi M, Kato H : Outcomes of grafting intrasynovial
tendons of the toes to the hands in 10 patients: a preliminary
report. J Hand Surg Eur Vol 42: 469-472, 2017.
20170258
Uemura K, Hayashi M, Itsubo T, Oishi A,
Iwakawa H, Komatsu M, Uchiyama S, Kato H : Myostatin
promotes tenogenic differentiation of C2C12 myoblast cells
through Smad3. FEBS Open Bio 7: 522-532, 2017.
20170259
Futatsugi T, Takahashi J, Oba H, Ikegami S,
Mogami Y, Shibata S, Ohji Y, Tanikawa H, Kato H : Early
Postoperative Magnetic Resonance Imaging in Detecting
Radicular Pain After Lumbar Decompression Surgery:
Retrospective Study of the Relationship Between Dural Sac
Cross-sectional Area and Postoperative Radicular Pain. Clin
Spine Surg 30: E733-E737, 2017.
20170260
Oba H, Tsutsumimoto T, Yui M, Kamanaka
T, Ohta H, Kosaku H, Misawa H : A prospective study ofrecovery from leg numbness following decompression
surgery for lumbar spinal stenosis. J Orthop Sci 22: 670-675,
2017.

T, Yonezawa I, Watanabe K, Matsumoto M; Committee
for Adult Deformity, Japanese Scoliosis Society : A
Japanese nationwide multicenter survey on perioperativecomplications of corrective fusion for elderly patients withadult spinal deformity. J Orthop Sci 22: 237-242, 2017.
20170264
Ebata S, Takahashi J, Hasegawa T, Mukaiyama
K, Isogai Y, Ohba T, Shibata Y, Ojima T, Yamagata Z,
Matsuyama Y, Haro H : Role of Weekly Teriparatide
Administration in Osseous Union Enhancement within Six
Months After Posterior or Transforaminal Lumbar Interbody
Fusion for Osteoporosis-Associated Lumbar Degenerative
Disorders: A Multicenter, Prospective Randomized Study. J
Bone Joint Surg Am 99: 365-372, 2017.
20170265
Maruyama M, Wakabayashi S, Ota H, Tensho
K : Reconstruction of the Shallow Acetabulum With a
Combination of Autologous Bulk and Impaction Bone
Grafting Fixed by Cement. Clin Orthop Relat Res 475: 387395, 2017.
20170266
Ogasawara T, Okano S, Ichimura H, Kadota S,
Tanaka Y, Minami I, Uesugi M, Wada Y, Saito N, Okada K,
Kuwahara K, Shiba Y : Impact of extracellular matrix onengraftment and maturation of pluripotent stem cell-derived
cardiomyocytes in a rat myocardial infarct model. Sci Rep 7:8630, 2017.
20170267
Akizuki S, Horiuchi H : Measured(Anatomical
Reference) Resection Technique for Cruciate^Retaining
Totak Knee Arthrolpasty. In: Matsuda S, Lusting S, Merwe
W. Soft Tissue Balancing in Total Knee Arthroplasty. Berlin:
Springer ; 2017. p.49-57.

Neurosurgery
20170261
Oba H, Takahashi J, Tsutsumimoto T, Ikegami
S, Ohta H, Yui M, Kosaku H, Kamanaka T, Misawa H, Kato
H : Predictors of improvement in low back pain after lumbar
decompression surgery: Prospective study of 140 patients. J
Orthop Sci 22: 641-646, 2017.
20170262
Oba H, Takahashi J, Takano K, Inaba Y,
Motobayashi M, Nishimura G, Kuraishi S, Shimizu M,
Ikegami S, Futatsugi T, Uehara M, Kosho T, Kato H,
Uno K : Rigid Occipitocervical Instrumented Fusion for
Atlantoaxial Instability in an 18-Month-Old Toddler With
Brachytelephalangic Chondrodysplasia Punctata: A Case
Report. Spine (Phila Pa 1976) 42: E1380-E1385, 2017.
20170263
Yamato Y, Matsuyama Y, Hasegawa K, Aota
Y, Akazawa T, Iida T, Ueyama K, Uno K, Kanemura T,
Kawakami N, Kotani T, Takaso M, Takahashi J, Tanaka
M, Taneichi H, Tsuji T, Hosoe H, Mochida J, Shimizu

20170268
Horiuchi T, Nagm A, Hasegawa T, Hongo
K : Transjugular tubercle-preaccessory approach forventrocaudally located PICA aneurysm. Acta Neurochir(Wien) 159: 641-644, 2017.
20170269
Horiuchi T, Nitta J, Miyaoka Y, Tsutsumi K, Ito
K, Hongo K : Open Embolectomy of Large Vessel Occlusionin the Endovascular Era: Results of a 12-Year Single-Center
Experience. World Neurosurg 102: 65-71, 2017.
20170270
Ito K, Nakamura T, Aoyama T, Horiuchi T,
Hongo K : A Case of Laterally Extended High-Positioned
Chordoma Treated Using the High Cervical Retropharyngeal
Approach. World Neurosurg 105: 1043.e15-1043.e19, 2017.
20170271
Kanaya K, Sakai K, Hongo K, Fukushima M,
Kawakubo M, Nakayama J : High expression of ADAM10

20

predicts a poor prognosis for patients with glioblastoma. Int
J Clin Exp Pathol 10(1): 618-624, 2017.

3011.

Dentistry & Oral Surgery
20170272
Kanaya K, Sakai K, Hongo K, Fukushima M,
Kawakubo M, Nakayama J : Reversion-Inducing CysteineRich Protein with Kazal Motifs (RECK) in Angiogenesisof Microvessels in Glioblastoma. Journal of Clinical andMolecular Pathology 1(2): 12, 2017.
20170273
Miyaoka Y, Takeuchi M, Wakao N, Aoyama M,
Hongo K, Takayasu M : Contusional Cerebellar Hemorrhage
Related to Placement in the Protrusion Position After
Atlantoaxial Fusion. World Neurosurg 101: 818.e7-818.e11,2017.
20170274
Nagm A, Ogiwara T, Goto T, Chiba A, Hongo
K : Neuroendoscopy via an Extremely Narrow Foramen of
Monro: A Case Report. NMC Case Rep J 4: 37-42, 2017.
20170275
Ogiwara T, Nagm A, Hanaoka Y, Nishikawa
A, Goto T, Horiuchi T, Hongo K : Management ofhypertrophied dural lesions: Is surgery a better option? . J
Neurol Sci 381: 245-249, 2017.
20170276
Ogiwara T, Nagm A, Yamamoto Y, Hasegawa T,
Nishikawa A, Hongo K : Clinical characteristics of pituitaryadenomas with radiological calcification. Acta Neurochir(Wien) 159: 2187-2192, 2017.
20170277
Ogiwara T, Goto T, Nagm A, Hongo K :Endoscopic endonasal transsphenoidal surgery using theiArmS operation support robot: initial experience in 43
patients. Neurosurgical Focus 42: E10, 2017.
20170278
Ogiwara T, Horiuchi T, Nagm A, Goto T,
Hongo K : Significance of surgical management for cystic
prolactinoma. Pituitary 20: 225-230, 2017.
20170279
Tsutsumi K, Horiuchi T, Nagm A, Toba Y,
Hongo K : Clinical characteristics of ruptured distal middle
cerebral artery aneurysms: Review of the literature. J Clin
Neurosci 40: 14-17, 2017.
20170280
Ts u t s u m i K , H o r i u c h i T, H o n g o K :Mechanical evaluation of cerebral aneurysm clip scissoring
phenomenon: comparison of titanium alloy and cobalt alloy.
J Mater Sci Mater Med 28: 159, 2017.
20170281
E. Sander Connolly, Jr., Gavin W. Britz,
Kazuhiro Hongo, Michael T. Lawton, Fredric B. Meyer: Vascular: Overview and Controversies. In: Winn, H.
Richard. Youmans & Winn Neurological Surgery, 7thedition, volume 4. Philadelphia: Elsevier; 2017. p.3009-

20170282
Shin-ichi Yamada, Hiroshi Kurita, Takahiro
Tomioka, Ryousuke Ohta, Nobuhiko Yoshimura, Fumihiro
Nishimaki, Yoshihito Koyama, Eiji Kondo, Takahiro Kamata: Healthy life expectancy of oral squamous cell carcinoma
patients aged 75 years and older. Oral oncology 64: 22-26,
2017.
20170283
Hasegawa T, Kawakita A, Ueda N, Funahara R,
Tachibana A, Kobayashi M, Kondou E, Takeda D, Kojima Y,
Sato S, .Yanamoto S, Komatsubara H, Umeda M, Kirita T,
Kurita H, Shibuya Y, Komori T : A multicenter retrospective
study of the risk factors associated with medicationrelated osteonecrosis of the jaw after tooth extraction inpatients receiving oral bisphosphonate therapy: can primarywound closure and a drug holiday really prevent MRONJ?.
Osteoporos Int 28: 2465-2473, 2017.
20170284
Xiangjun Li, Hiroshi Kurita, Tiepeng Xiao,
Kyou Iijima, Kenji Kurashina, Jun Nakayama : Potential
involvement of chondroitin sulfate A in the pathogenesis ofameloblastoma. Acta Histochem 119: 439-445, 2017.
20170285
Nakao Y, Yamada S, Yanamoto S, Tomioka T,
Naruse T, Ikeda T, Kurita H, Umeda M. : Natriuretic peptide
receptor A is related to the expression of vascular endothelial
growth factors A and C, and is associated with the invasion
potential of tongue squamous cell carcinoma. Int J Oral
Maxillofac Surg 46: 1237-1242, 2017.
20170286
Tanaka M, Kamata T, Yanagisawa R, Morita
D, Saito S, Sakashita K, Shiohara M, Kurita H, Koike
K, Nakazawa Y : Increasing Risk of Disturbed RootDevelopment in Permanent Teeth in Childhood Cancer
Survivors Undergoing Cancer Treatment at Older Age. J
Pediatr Hematol Oncol 39: e150-e154, 2017.
20170287
Yanamoto S, Hasegawa T, Rokutanda S,
Komori S, Tachibana A, Kojima Y, Koyama Y, Shibuya Y,
Kurita H, Komori T, Umeda M : Multicenter Retrospective
Study of the Risk Factors of Hemorrhage After Tooth
Extraction in Patients Receiving Antiplatelet Therapy. J Oral
Maxillofac Surg 75: 1338-1343, 2017.
20170288
Kojima Y, Yanamoto S, Umeda M, Kawashita
Y, Saito I, Hasegawa T, Komori T, Ueda N, Kirita T, Yamada
S, Kurita H, Senga Y, Shibuya Y, Iwai H : Relationshipbetween dental status and development of osteoradionecrosisof the jaw: a multicenter retrospective study. OOOO 124:
139-145, 2017.

21

20170289
Aizawa H, Yamada S, Xiao T, Shimane T,
Hayashi K, Qi F, Tanaka H, Kurita H : Difference inglycogen metabolism (glycogen synthesis and glycolysis)
between normal and dysplastic/malignant oral epithelium.
Arch Oral Biol 83: 340-347, 2017.
20170290
Hasegawa T, Yanamoto S, Tachibana A, Kojima
Y, Koyama Y, Maeda M , Komori T : The risk factors
associated with postoperative hemorrhage after tooth
extraction: a multi-center retrospective study of patients
receiving oral antithrombotic therapy. Oral Maxillofac Surg
21: 397-404, 2017.
20170291
Sakiko Soutome, Souichi Yanamoto, Madoka
Funahata, Takumi Hasegawa, Takahide Komori, Shin-ichi
Yamada, Hirishi Kurita Chika Yamauchi, Yasuyuki Shibuya,
Yuka Kojima, Hirokazu Nakahara, Takahiko Oho, Masahiro
Umeda : Effect of perioperative oral care on prevention of
postoperative pneumonia associated with esophageal cancer
surgery. Medicine (Baltimore) 96(33): e7436, 2017.
20170292
M a d o k a F u n a h a t a , S o u i c h i Ya n a m o t o ,Michihiro Ueda, Takatsugu Suzuki, Yoshihide Ota, Fumihiro
Nishimaki, Hiroshi Kurita, Nobuhiro Yamakawa, Tadaaki
Kirita, Masaya Okura, Yasuaki Mekaru, Keiichi Arakaki,
Masahiro Umeda : Prevention of surgical site infection after
oral cancer surgery by topical tetracycline: Results of amulticenter randomized control trial. Medicine (Baltimore)
96(48): e8891, 2017.

Urology
20170293
Imamura T, Ogawa T, Minagawa T, Nagai T,
Suzuki T, Saito T, Yokoyama H, Nakazawa M, Ishizuka O: Combined treatment with a β3-adrenergic receptor agonist
and a muscarinic receptor antagonist inhibits detrusor
overactivity induced by cold stress in spontaneously
hypertensive rats. Neurourol Urodyn 36: 1026-1033, 2017.
20170294
Ishikawa M, Imamura T, Nishizawa O, Ishizuka
O : Implantation of autologous bone marrow-derived cells
improves erectile dysfunction in spontaneously hypertensive
rats. Shinshu Medical Journal 65(1): 37-44, 2017.
20170295
S h i m i z u S , Ya m a m o t o T, N a k a y a m a S ,Hirakawa A, Kuwatsuka Y, Funahashi Y, Matsukawa Y,
Takanari K, Toriyama K, Kamei Y, Narimoto K, Yamanishi
T, Ishizuka O, Mizuno M, Gotoh M : Design of a single-arm
clinical trial of regenerative therapy by periurethral injectionof adipose-derived regenerative cells for male stress urinary
incontinence in Japan: the ADRESU study protocol. BMC
Urol 17(1): 89, 2017.

20170296
Ogawa T, Sakakibara R, Kuno S, Ishizuka O,
Kitta T, Yoshimura N : Prevalence and treatment of LUTS inpatients with Parkinson disease or multiple system atrophy.
Nat Rev Urol 14(2): 79-89, 2017.
20170297
Wyndaele JJ, Birch B, Borau A, Burks F,
Castro-Diaz D, Chartier-Kastler E, Drake M, Ishizuka O,
Minagawa T, Opisso E, Padilla-Fernandez B, Peters K,
Reus C, Sekido N : Surgical management of neurogenic
bladder after spinal cord injury. In: Elliott S, Gómez R(eds).
Urologic management of the spinal cord injured patient.
Montreal: A Joint SIU-ICUD International consultation;2017. p.209-213.

Ophthalmology
20170298
Hirano T, Toriyama Y, Iesato Y, Imai A,
Hirabayashi K, Nagaoka T, Takamura Y, Sugimoto M,
Murata T : Effect of leaking perifoveal microaneurysms on
resolution of diabetic macular edema treated by combination
therapy using anti-vascular endothelial growth factor
and short pulse focal/grid laser photocoagulation. Jpn J
Ophthalmol 61: 51-60, 2017.
20170299
Imai A, Toriyama Y, Iesato Y, Hirabayashi K,
Sakurai T, Kamiyoshi A, Ichikawa-Shindo Y, Kawate H,
Tanaka M, Liu T, Xian X, Zhai L, Dai K, Tanimura K, Liu T,
Cui N, Yamauchi A, Murata T, Shindo T : Adrenomedullin
Suppresses Vascular Endothelial Growth Factor-Induced
Va s c u l a r H y p e r p e r m e a b i l i t y a n d I n f l a m m a t i o n i nRetinopathy. Am J Pathol 187: 999-1015, 2017.

Otorhinolaryngology
20170300
Moteki H, Nishio S, Miyagawa M, Tsukada
K, Iwasaki S, Usami S : Long-term results of hearing
preservation cochlear implant surgery in patients withresidual low frequency hearing. Acta Otolaryngol 137(5):516-521, 2017.
20170301
K o r v e r A M , S m i t h R J , Va n C a m p G ,Schleiss MR, Bitner-Glindzicz MA, Lustig LR, Usami SI,
Boudewyns AN : Congenital hearing loss. Nat Rev Dis
Primers 3: 16094, 2017.
20170302
Nishio SY, Usami SI : The Clinical NextGeneration Sequencing Database: A Tool for the Unified
Management of Clinical Information and Genetic Variants to
Accelerate Variant Pathogenicity Classification. Hum Mutat
38(3): 252-259, 2017.
20170303
Van de Heyning P, Távora-Vieira D, Mertens G,
Van Rompaey V, Rajan GP, Müller J, Hempel JM, Leander22

D, Polterauer D, Marx M, Usami SI, Kitoh R, Miyagawa
M, Moteki H, Smilsky K, Baumgartner WD, Keintzel TG,
Sprinzl GM, Wolf-Magele A, Arndt S, Wesarg T, Zirn S,
Baumann U, Weissgerber T, Rader T, Hagen R, Kurz A,
Rak K, Stokroos R, George E, Polo R, Medina M, Henkin
Y, Hilly O, Ulanovski D, Rajeswaran R, Kameswaran M,
Di Gregorio MF, Zernotti ME : Towards a Unified Testing
Framework for Single-Sided Deafness Studies: A Consensus
Paper. Audiol Neurootol 21(6): 391-398, 2017.
20170304
Morita S, Fujiwara K, Fukuda A, Fukuda S,
Nishio SY, Kitoh R, Hato N, Ikezono T, Ishikawa K, Kaga
K, Matsubara A, Matsunaga T, Murata T, Naito Y, Nishizaki
K, Ogawa K, Sano H, Sato H, Sone M, Suzuki M, Takahashi
H, Tono T, Yamashita H, Yamasoba T, Usami SI : The
clinical features and prognosis of mumps-associated hearing
loss: a retrospective, multi-institutional investigation in
Japan. Acta Otolaryngol 137(sup565): S44-S47, 2017.
20170305
Nishio SY, Takumi Y, Usami SI : Laser-capture
micro dissection combined with next-generation sequencing
analysis of cell type-specific deafness gene expression in themouse cochlea. Hear Res 348: 87-97, 2017.
20170306
Noguchi Y, Fukuda S, Fukushima K, Gyo K,
Hara A, Nakashima T, Ogawa K, Okamoto M, SatoH, Usami
SI, Yamasoba T, Yokoyama T, Kitamura K : A nationwide
study on enlargement of the vestibular aqueduct in Japan.
Auris Nasus Larynx 44(1): 33-39, 2017.
20170307
Okada M, Hato N, Nishio SY, Kitoh R, Ogawa
K, Kanzaki S, Sone M, Fukuda S, Hara A, Ikezono T,
Ishikawa K, Iwasaki S, Kaga K, Kakehata S, Matsubara A,
Matsunaga T, Murata T, Naito Y, Nakagawa T, Nishizaki
K, Noguchi Y, Sano H, Sato H, Suzuki M, Shojaku H,
Takahashi H, Takeda H, Tono T, Yamashita H, Yamaso : The
effect of initial treatment on hearing prognosis in idiopathic
sudden sensorineural hearing loss: a nationwide survey inJapan. Acta Otolaryngol 137(sup565): S30-S33, 2017.
20170308
Usami SI, Kitoh R, Moteki H, Nishio SY,
Kitano T, Kobayashi M, Shinagawa J, Yokota Y, Sugiyama
K, Watanabe K : Etiology of single-sided deafness andasymmetrical hearing loss. Acta Otolaryngol 137(sup565):
S2-S7, 2017.
20170309
Kitoh R, Nishio SY, Ogawa K, kanzaki S, Hato
N, Sone M, Fukuda S, Hara A, Ikezono T, Ishikawa K,
Iwasaki S, Kaga K, Kakehata S, Matsubara A, Matsunaga
T, Murata T, Naito Y, Nakagawa T, Nishizaki K, Noguchi Y,
Sano H, Sato H, Sato H, Suzuki M, Shojaku H, Takahashi
H, Takeda H, Tono T, Yamashita H, Yamasoba T, Usami SI: Nationwide epidemiological survey of idiopathic sudden

sensorineural hearing loss in Japan. Acta Otolaryngol
137(sup565): S8-S16, 2017.
20170310
Wada T, Sano H, Nishio SY Kitoh R, Ikezono
T, Iwasaki S, Kaga k, matsubara A, Matsunaga T, Murata
T, naito Y, Suzuki M, Takahashi H, Tono T, Yamashita H,
Hara A, Usami SI : Differences between acoustic trauma
and other types of acute noise-induced hearing loss interms of treatment and hearing prognosis. Acta Otolaryngol
137(sup565): S48-S52, 2017.
20170311
Kitoh R, Nishio SY, Usami SI : Prognostic
impact of gene polymorphisms in patients with idiopathic
sudden sensorineural hearing loss. Acta Otolaryngol
137(sup565): S24-S29, 2017.
20170312
Umesawa M, Kobashi G, Kitoh R, Nishio SY,
Ogawa K, Hato N, Sone M, Fukuda S, Hara A, Ikezono T,
Ishikawa K, Iwasaki S, Kaga K, Kakehata S, Matsubara A,
Matsunaga T, Murata T, Naito Y, Nakagawa T, Nishizaki
K, Noguchi Y, Sano H, Sato H, Suzuki M, Shojaku H,
Takahashi H, Takeda H, Tono T, Yamashita H, Yamasoba
T, Usami SI : Relationships among drinking and smoking
habits, history of diseases, body mass index and idiopathic
sudden sensorineural hearing loss in Japanese patients. Acta
Otolaryngol 137(sup565): S17-S23, 2017.
20170313
Usami SI : Acute sensorineural hearing loss.
Acta Otolaryngol 137(sup565): S1-S1, 2017.
20170314
Matsuda H, Sakamoto K, Matsumura T,
Saito S, Shindo S, Fukushima K, Nishio SY, Kitoh R,
Shibasaki O, Ito A, Araki R, Usami SI Suzuki M, Ogawa K,
Hasegawa T, Hagiwara Y, Kase Y, Ikezono T : A nationwide
multicenter study of the Cochlin tomo-protein detection test:
clinical characteristics of perilymphatic fistula cases. Acta
Otolaryngol 137(sup565): S53-S59, 2017.
20170315
Sato H, Kuwashima S, Nishio SY, Kitoh R,
Fukuda S, Hara A, Hato N, Ikezono T, Ishikawa K, Iwasaki
S, Kaga K, Matsubara A, Matsunaga T, Murata T, Naito Y,
Nakagawa T, Nishizaki K, Noguchi Y, Ogawa K, Sano H,
Sone M, Shojaku H, Takahashi H, Tono T, Yamashita H,
Yamasoba T, Usami SI : Epidemiological survey of acutelow-tone sensorineural hearing loss. Acta Otolaryngol
137(sup565): S34-S37, 2017.
20170316
Nishio SY, Usami SI : Outcomes of cochlear
implantation for the patients with specific genetic etiologies:
a systematic literature review. Acta Otolaryngol 137(7): 730742, 2017.
20170317

Yoshida T, Sone M, Kitoh R, Nishio SY,

23

Ogawa K, Kanzaki S, Hato N, Fukuda S, Hara A, Ikezono
T, Ishikawa K, Iwasaki S, kaga K, kakehata S, Matsubara
A, Matsunaga T, Murata T, Naito Y, Nakagawa T, Nishizaki
K, Noguchi Y, Sano H, Sato H, Suzuki M, Shojaku H,
Takahashi H, Takeda H, Tono T, Yamashita H, Yamasoba T,
Usami SI : Idiopathic sudden sensorineural hearing loss andacute low-tone sensorineural hearing loss: a comparison of
the results of a nationwide epidemiological survey in Japan.
Acta Otolaryngol 137(sup565): S38-S43, 2017.
20170318
Kitano T, Miyagawa M, Nishio SY, Moteki H,
Oda K, Ohyama K, Miyazaki H, Hidaka H, Nakamura KI,
Murata T, Matsuoka R, Ohta Y, Nishiyama N, Kumakawa
K, Furutate S, Iwasaki S, Yamada T, Ohta Y, Uehara N,
Noguchi Y, Usami SI : POU4F3 mutation screening inJapanese hearing loss patients: Massively parallel DNA
sequencing-based analysis identified novel variants
associated with autosomal dominant hearing loss. PLoS
ONE 12(5): e0177636, 2017.
20170319
Iwasaki S, Usami SI, Takahashi H, Kanda Y,
Tono T, Doi K, Kumakawa K, Gyo K, Naito Y, Kanzaki S,
Yamanaka N, Kaga K : Round Window Application of an
Active Middle Ear Implant: A Comparison With Hearing Aid
Usage in Japan. Otol Neurotol 38(6): e145-e151, 2017.
20170320
Arai Y, Takahashi M, Sakuma N, Nishio S,
Oridate N, Usami SI : Compound heterozygous dominant
and recessive GJB2 mutations cause deafness withpalmoplantar karatoderma. Acta Otolaryngol Case Rep 2(1):137-140, 2017.
20170321
Raian G, Tavora-Vieira D, Baumqartner WD,
Godey B, Müller J, O'Driscoll M, Skarzynski H, Skarzynski
P, Usami SI, Adunka O, Aqrawal S, Bruce I, De Bodt M,
Caversaccio M, Pilsbury H, Gavila J, Haqen R, haqr A,
Kameswaran M, Karltorp E, Kompis M, Kuzovkov V,
lassaletta L, Yonqxin L, Lorens A, Manoi M, Martin J,
Mertens G, Mlynski R, Parned L, Pulibalathingal S, Radeloff
A, Raine CH, Raieswaran R, Schmutzhard J, Sprinzl G,
Staecker H, Stephan K, Suqarova S, Zernotti M, Zprpwka
P, Van de Heyning P : Hearing preservation cochlear
implantation in children: The HEARRING Group consensus
and practice guide. Cochlear Implants Int 19: 1-13, 2017.

Ida K, Mvunta DH, Shiozawa T : Panobinostat Enhances
Growth Suppressive Effects of Progestin on Endometrial
Carcinoma by Increasing Progesterone Receptor and
Mitogen-Inducible Gene-6. Horm Cancer 8: 257-267, 2017.
20170324
Ohira S, Asaka R, Tanaka Y, Fuseya C,
Ando H, Kikuchi N, Miyamoto T, Kanai M, Shiozawa
T : Management of a Pregnant Woman with Idiopathic
Interstitial Pneumonia Accompanied by Secondary
Pulmonary Hypertension: Case Report and Literature
Review. Med Case Rep (Wilmington) 3: 46, 2017.
20170325
Kobayashi Y, Kashima H, Rahmanto YS,
Banno K, Yu Y, Matoba Y, Watanabe K, Iijima M, Takeda
T, Kunitomi H, Iida M, Adachi M, Nakamura K, Tsuji
K, Masuda K, Nomura H, Tominaga E, Aoki D : Drugrepositioning of mevalonate pathway inhibitors as antitumor
agents for ovarian cancer. Oncotarget 8: 72147-72156, 2017.
20170326
Kobara H, Kashima H, Miyamoto T, Yamada
Y, Asaka S, Shiozawa T : A case of pure-type ovariansquamous cell carcinoma producing granulocyte-colony
stimulating factor. Gynecol Oncol Rep 22: 89-91, 2017.

Anesthesiology and Resuscitology
20170327
Sugiyama Y, Mitsuzawa K, Yoshiyama Y,
Shimizu F, Fuseya S, Ichino T, Agatsuma H, Shiina T, Ito K,
Kawamata M : Difficult Management of a Double-Lumen
Endotracheal Tube and Difficult Ventilation during Robotic
Thymectomy with Carbon Dioxide Insufflation. Case Rep
Surg 2017: 3403045, 2017.
20170328
Sugiyama Y, Tanaka R, Yoshiyama Y, Ichino T,
Hishinuma N, Shimizu S, Imai N, Mitsuzawa K, Kawamata
M : A case of sudden onset of thyroid storm just before
cesarean section manifesting congestive heart failure andpulmonary edema. JA Clin Rep 3: 20, 2017.

Plastic and Reconstructive Surgery
20170329
Yasunaga Y, Matsuo K, Tanaka Y, Yuzuriha S: Near-infrared irradiation increases length of axial pattern
flap survival in rats. Eplasty 17: 232-242, 2017.

Obstetrics and Gynecology

Laboratory Medicine

20170322
Mvunta DH, Miyamoto T, Asaka R, Yamada Y,
Ando H, Higuchi S, Ida K, Kashima H, Shiozawa T : SIRT1
Regulates the Chemoresistance and Invasiveness of Ovarian
Carcinoma Cells. Transl Oncol 10: 621-631, 2017.

20170330
Fukatsu H, Yashio A, Honda T : Bacteremia
Caused by Yokenella regensburgei in a Patient with Diabetes
Mellitus. Shinshu Med J 65(2): 113-116, 2017.

20170323

Ando H, Miyamoto T, Kashima H, Higuchi S,

20170331
Uchida M, Kaneko M, Hidaka Y, Yamamoto
H, Honda T, Takeuchi S, Saito M, Kawa S : Effectiveness24of vaccination and wearing masks on seasonal influenza
in Matsumoto City, Japan, in the 2014/2015 season: An
observational study among all elementary schoolchildren.
Prev Med Rep 5: 86-91, 2017.
20170332
Fujimoto M, Yoshizawa A, Sumiyoshi S,
Sonobe M, Menju T, Hirata M, Momose M, Date H, Haga
H : Adipophilin expression in lung adenocarcinoma is
associated with apocrine-like features and poor clinicalprognosis: an immunohistochemical study of 328 cases.
Histopathology 70(2): 232-241, 2017.
20170333
Kawakubo M, Horiuchi K, Komura H, Sato Y,
Kato M, Ikeyama M, Fukushima M, Yamada S, Ishizone
S, Matsumoto T, Ota H, Sagara J, Nakayama J : Cloningof Helicobacter suis cholesterol α-glucosyltransferase
and production of an antibody capable of detecting it informalin-fixed, paraffin-embedded gastric tissue sections.
Histochem Cell Biol 148(4): 463-471, 2017.
20170334
Uchibori T, Matsuda K, Shimodaira T, Sugano
M, Uehara T, Honda T : IL-6 trans-signaling is anotherpathway to upregulate Osteopontin. Cytokine 90: 88-95,
2017.
20170335
Nagata K, Arai S, Taira C, Sugano M, Honda T,
Okumura N : A novel frameshift mutation in the fibrinogenγC terminal region, FGG c.1169_1170 del AT, leading tohypofibrinogenemia. Thromb Res 159: 82-85, 2017.
20170336
Sano K, Asahina M, Uehara T, Matsumoto K,
Araki N, Okuyama R : Degranulation and shrinkage of darkcells in eccrine glands and elevated serum carcinoembryonicantigen in patients with acquired idiopathic generalized
anhidrosis. J Eur Acad Dermatol Venereol 31(12): 20972103, 2017.
20170337
Hayashi T, Kawano M, Sano K, Ichimura T, Gur
G, Yaish P, Zharhary D, Kanai Y, Tonegawa S, Shiozawa
T, Yaegashi N, Konishi I : A novel diagnostic biomarker
for human uterine leiomyosarcoma: PSMB9/β1i. Chin Clin
Oncol 6(2): 22, 2017.
20170338
Kimura T, Kobayashi A, Tanaka N, Sano K,
Komatsu M, Fujimori N, Yamazaki T, Shibata S, Ichikawa
Y, Joshita S, Umemura T, Matsumoto A, Horiuchi A,
Mori H, Wada S, Kiyosawa K, Miyagawa SI, Tanaka
E : Clinicopathological characteristics of non-B non-C
hepatocellular carcinoma without past hepatitis B virus
infection. Hepatol Res 47(5): 405-418, 2017.
20170339
Kitabatake H, Tanaka N, Fujimori N, Komatsu
M, Okubo A, Kakegawa K, Kimura T, Sugiura A, Yamazaki

T, Shibata S, Ichikawa Y, Joshita S, Umemura T, Matsumoto
A, Koinuma M, Sano K, Aoyama T, Tanaka E : Association
between endotoxemia and histological features ofnonalcoholic fatty liver disease. World J Gastroenterol 23(4):712-722, 2017.
20170340
Koya T, Yanagisawa R, Higuchi Y, Sano K,
Shimodaira S : Interferon-α-inducible Dendritic Cells
Matured with OK-432 Exhibit TRAIL and Fas Ligand
Pathway-mediated Killer Activity. Sci Rep 7: 42145, 2017.
20170341
Munetsugu T, Fujimoto T, Oshima Y, Sano
K, Murota H, Satoh T, Iwase S, Asahina M, Nakazato
Y, Yokozeki H : Revised guideline for the diagnosis andtreatment of acquired idiopathic generalized anhidrosis inJapan. J Dermatol 44(4): 394-400, 2017.
20170342
Ozawa Y, Yamamoto H, Yasuo M, Takahashi
H, Tateishi K, Ushiki A, Kawakami S, Fujinaga Y, Asaka
S, Sano K, Takayama H, Imamura H, Hanaoka M : Twopatients with TAFRO syndrome exhibiting strikingly
similar anterior mediastinal lesions with predominantly fat
attenuation on chest computed tomography. Respir Investig
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20170343
O n o M , K a s u g a Y, U e h a r a T, O d a Y :Epithelioid hemangioendothelioma of the thyroid: a casereport. Surg Case Rep 3(1): 18, 2017.
20170344
Hosoda W, Chianchiano P, Griffin JF, Pittman
ME, Brosens LA, Noë M, Yu J, Shindo K, Suenaga
M, Rezaee N, Yonescu R, Ning Y, Albores-Saavedra J,
Yoshizawa N, Harada K, Yoshizawa A, Hanada K, Yonehara
S, Shimizu M, Uehara T, Samra JS, Gill AJ, Wolfgang CL,
Goggins MG, Hruban RH, Wood LD : Genetic analyses
of isolated high-grade pancreatic intraepithelial neoplasia(HG-PanIN) reveal paucity of alterations in TP53 andSMAD4. J Pathol 242(1): 16-23, 2017.
20170345
Muraki T, Memis B, Reid MD, Uehara T,
Ito T, Hasebe O, Okaniwa S, Horigome N, Hisa T, Mittal
P, Freedman A, Maithel S, Sarmiento JM, Krasinskas A,
Koshiol J, Adsay V : Reflux-Associated Cholecystopathy:
Analysis of 76 Gallbladders From Patients With SupraOddi Union of the Pancreatic Duct and Common Bile
Duct (Pancreatobiliary Maljunction) Elucidates a SpecificDiagnostic Pattern of Mucosal Hyperplasia as a Prelude to
Carcinoma. Am J Surg Pathol 41(9): 1167-1177, 2017.
20170346
Droma Y, Kato A, Ichiyama T, Kobayashi N,
Honda T, Uehara T, Hanaoka M : Electron Microscopy
Observation of Human Pulmonary Ultrastructure in Two
Patients with High-Altitude Pulmonary Edema. High Alt

25

Med Biol 18(3): 288-291, 2017.
20170347
Iesato A, Nakamura T, Izumi H, Uehara T, Ito
KI : PATZ1 knockdown enhances malignant phenotype inthyroid epithelial follicular cells and thyroid cancer cells.
Oncotarget 8(47): 82754-82772, 2017.

20170355
Asaka S, Yoshizawa A, Matsuda K, Yamaguchi
A, Yamamoto H, Shiina T, Nakata R, Ogawa K, Zhang M,
Honda T : A novel, rapid point-of-care test for lung cancer
patients to detect epidermal growth factor receptor genemutations by using real-time droplet-PCR and fresh liquid
cytology specimens. Oncol Rep 37(2): 1020-1026, 2017.

20170348
Kitabatake H, Nagaya T, Tanaka N, Ota H,
Sano K, Asano N, Suga T, Nakamura Y, Akamatsu T,
Tanaka E : Development of diffuse large B-cell lymphoma
from follicular lymphoma of the duodenum: changes inendoscopic findings during a 6-year follow-up. Clin J
Gastroenterol 10(1): 79-85, 2017.

20170356
Nakajima N, Yoshizawa A, Kondo K, RokutanKurata M, Hirata M, Furuhata A, Sumiyoshi S, Sonobe
M, Menju T, Momose M, Fujimoto M, Date H, Haga H :Evaluating the effectiveness of RNA in-situ hybridization for
detecting lung adenocarcinoma with anaplastic lymphoma
kinase rearrangement. Histopathology 71(1): 143-149, 2017.

20170349
Kinugawa Y, Uehara T, Sano K, Matsuda K,
Maruyama Y, Kobayashi Y, Nakajima T, Hamano H, Kawa
S, Higuchi K, Hosaka N, Shiozawa S, Ishigame H, Ota H: Methylation of Tumor Suppressor Genes in Autoimmune
Pancreatitis. Pancreas 46(5): 614-618, 2017.

20170357
Rokutan-Kurata M, Yoshizawa A, Sumiyoshi
S, Sonobe M, Menju T, Momose M, Koyama M, Shigeto S,
Fujimoto M, Zhang M, Morita S, Date H, Haga H : Lung
Adenocarcinoma With MUC4 Expression Is AssociatedWith Smoking Status, HER2 Protein Expression, and Poor
Prognosis: Clinicopathologic Analysis of 338 Cases. Clin
Lung Cancer 18(4): e273-e281, 2017.

20170350
Taira C, Matsuda K, Arai S, Sugano M, Uehara
T, Okumura N : A Novel Mutation in the Fibrinogen Bβ
Chain (c.490G>A; End of Exon 3) Causes a Splicing
Abnormality and Ultimately Leads to CongenitalHypofibrinogenemia. Int J Mol Sci 18(11): 2470, 2017.
20170351
I c h i m a t a S , Yo s h i z a w a A , K u s a k a r i M ,Nakayama Y, Asaka S, Negishi T, Kasuga E, Matsumoto
T, Honda T : Human intestinal spirochetosis in Japanesepatients aged less than 20 years: Histological analysis ofcolorectal biopsy and surgical specimens obtained from 479
patients. Pathol Int 67(6): 302-305, 2017.
20170352
Arai S, Ogiwara N, Mukai S, Takezawa
Y, Sugano M, Honda T, Okumura N : The fibrous formof intracellular inclusion bodies in recombinant variant
fibrinogen-producing cells is specific to the hepatic
fibrinogen storage disease-inducible variant fibrinogen. Int J
Hematol 105(6): 758-768, 2017.
20170353
Uchida M, Kaneko M, Hidaka Y, Yamamoto
H, Honda T, Takeuchi S, Saito M, Kawa S : Prospective
Epidemiological Evaluation of Seasonal Influenza in All
Elementary Schoolchildren in Matsumoto City, Japan, in
2014/2015. Jpn J Infect Dis 70(3): 333-339, 2017.
20170354
K o m a t s u M , H a c h i y a T, Ta k a h a s h i H ,Yoshikawa S, Honda T : Direct hemoperfusion withpolymyxin B-immobilized fiber for the treatment of theacute exacerbation of idiopathic pulmonary fibrosis inpatients requiring invasive mechanical ventilation. Respir
Investig 55(5): 318-322, 2017.

Emergency and Critical Care Medicine
20170358
Mochizuki K, Shintani R, Mori K, Sato
T, Sakaguchi O, Takeshige K, Nitta K, Imamura H :Importance of respiratory rate for the prediction of clinicaldeterioration after emergency department discharge: asingle-center, case-control study. Acute Med Surg 4: 172178, 2017.
20170359
Takayama H : A case of cerebral infarction withfavorable outcome that occurred while climbing a 2400m
mountain -Successful prehospital emergency medical serviceof mountain rescue-. Shinshu Med J 65: 259-265, 2017.
20170360
Ichikawa M, Oishi S, Mochizuki K, Nitta K,
Okamoto K, Imamura H : Influence of body position during
Heimlich maneuver to relieve supralaryngeal obstruction: amanikin study. Acute Med Surg 4: 418-425, 2017.
20170361
Okada A, Kashima Y, Tomita T, Takeuchi
T, Oguchi Y, Yoshie K, Shoin W, Shoda M, Nitta K,
Kuwahara K, Imamura H : Cardiac hyaluronan may be
associated with the persistence of atrial fibrillation. Heart
Vessels 32: 1144-1150, 2017.
20170362
Ozawa Y, Yamamoto H, Yasuo M, Takahashi
H, Tateishi K, Ushiki A, Kawakami S,Fujinaga Y, Asaka
S, Sano K, Takayama H, Imamura H, Hanaoka M : Twopatients with TAFRO syndrome exhibiting strikingly
similar anterior mediastinal lesions with predominantly fat
attenuation on chest computed tomography. Respir Investig

26

55: 176-180, 2017.

Comprehensive Cancer Therapy
20170363
Gomi D, Tanaka A, Fukushima T, Kobayashi T,
Matsushita H, Sekiguchi N, Sakamoto A, Sasaki S, Mamiya
K, Koizumi T : Dynamics of L-Carnitine in Plasma andUrine in Patients Undergoing Cisplatin Chemotherapy.
Chemotherapy 62(4): 225-230, 2017.
20170364
Ichiyama T, Gomi D, Fukushima T, Kobayashi
T, Sekiguchi N, Sakamoto A, Sasaki S, Mamiya K,
Koizumi T, Hama Y : Successful and long-term response to
trastuzumab plus paclitaxel combination therapy in humanepidermal growth factor receptor 2-positive extramammary
Paget's disease: A case report and review of the literature.
Mol Clin Oncol 7(5): 763-766, 2017.
20170365
Kikuchi T, Shimizu H, Akiyama Y, Taniguchi
S : In situ delivery and production system of trastuzumab
scFv with Bifidobacterium. Biochem Biophys Res Commun493(1): 306-312, 2017.
20170366
Kitazawa M, Hida S, Fujii C, Taniguchi S,
Ito K, Matsumura T, Okada N, Sakaizawa T, Kobayashi
A, Takeoka M, Miyagawa S : ASC Induces Apoptosis
via Activation of Caspase-9 by Enhancing Gap JunctionMediated Intercellular Communication. PLoS One 12(1):e0169340, 2017.
20170367
Koizumi T, Fukushima T, Gomi D, Kobayashi
T, Sekiguchi N, Mamiya K, Tateishi K, Katou A, Oguchi K: Correlation of early PET findings with tumor response tomolecular targeted agents in patients with advanced drivermutated non-small cell lung cancer. Med Oncol 34(10): 169,2017.
20170368
Maruyama Y, Fukushima T, Gomi D, Kobayashi
T, Sekiguchi N, Sakamoto A, Sasaki S, Mamiya K, Koizumi
T : Relapsed and unresectable inflammatory myofibroblastic
tumor responded to chemotherapy: A case report and reviewof the literature. Mol Clin Oncol 7(4): 521-524, 2017.
20170369
Miura K, Hamanaka K, Koizumi T, Kitaguchi
Y, Terada Y, Nakamura D, Kumeda H, Agatsuma H,
Hyogotani A, Kawakami S, Yoshizawa A, Asaka S, Ito K :Clinical significance of preoperative serum albumin level for
prognosis in surgically resected patients with non-small celllung cancer: Comparative study of normal lung, emphysema,and pulmonary fibrosis. Lung Cancer 111: 88-95, 2017.
20170370
Nakamura D, Miura K, Kumeda H, Agatsuma
H, Hyogotani A, Hamanaka K, Koizumi T, Yamamoto H,

Tamada H, Ito K : Successful Resection of G719X-Positive
Pleomorphic Carcinoma after Afatinib Treatment. Case Rep
Oncol 10: 1035-1040, 2017.
20170371
Nishie K, Yamamoto S, Nagata C, Koizumi T,
Hanaoka M : Anamorelin for advanced non-small-cell lungcancer with cachexia: Systematic review and meta-analysis.
Lung Cancer 112: 25-34, 2017.
20170372
Okamoto M, Takazawa A, Aoki K, Yoshimura
Y, Kato H, Otsuki T, Maeno K, Koizumi T : Initial clinicalpresentation of single soft tissue metastasis of medullary
thyroid carcinoma without primary rumor in the thyroid
gland. World J Surg Oncol 15(1): 221, 2017.
20170373
Ozawa T, Koiwai K, Matsushita H, Kadoya M: Dosimetric Comparisons of Volumetric Modulated Arc
Therapy with Three-Dimensional Conformal Radiation
Therapy for Locally Advanced Non-Small Cell Lung Cancer.
Shinshu Med J 65(2): 93-98, 2017.
20170374
Sakamoto A, Tsukahara Y, Gomi D, Fukushima
T, Kobayashi T, Matsushita H, Sekiguchi N, Mamiya K,
Koizumi T : Plasma L-carnitine levels in terminally illcancer patients receiving only palliative care. Ann Palliat
Med 6(suppl 1): S52-S57, 2017.
20170375
Sekiguchi N, Nishina S, Kawakami T, Sakai H,
Senoo N, Senoo Y, Ito T, Saito H, Nakazawa H, Koizumi T,
Ishida F : Oral cyclophosphamide was effective for Coombsnegative autoimmune hemolytic anemia in CD16+CD56chronic lymphoproliferative disorder of NK-cells. Int J
Hematol 105(6): 854-858, 2017.
20170376
Seno N, Fukushima T, Gomi D, Kobayashi
T, Sekiguchi N, Matsushita H, Ozawa T, Tsukahara Y,
Mamiya K, Koizumi T, Sano K : Successful treatment
with doxorubicin and ifosfamide for mediastinal malignant
peripheral nerve sheath tumor with loss of H3K27me3
expression. Thorac Cancer 8(6): 720-723, 2017.
20170377
Takeuchi N, Koike K, Yoshida S, Kubo A,
Sekiguchi N, Nakayama A, Kubota K, Rokuhara T, Kitahara
M : Treatment of metastatic refractory colorectal cancer
following regorafenib failure. Mol Clin Oncol 7(2): 308-312,2017.
20170378
Ta n a h a s h i T, S e k i g u c h i N , M a t s u d a K ,Matsumoto A, Ito T, Nakazawa H, Ishida F : A screening
method with lymphocyte percentage and proportion of
granular lymphocytes in the peripheral blood for large
granular lymphocyte (LGL) leukemia. Int J Hematol 105(1):87-91, 2017.

27

20170379
Yamaguchi M, Suzuki R, Oguchi M, Asano N,
Amaki J, Akiba T, Maeda T, Itasaka S, Kubota N, Saito Y,
Kobayashi Y, Itami J, Ueda K, Miyazaki K, Ii N, Tomita
N, Sekiguchi N, Takizawa J, Saito B, Murayama T, Ando
T, Wada H, Hyo R, Ejima Y, Hasegawa M, Katayama N: Treatments and Outcomes of Patients With Extranodal
Natural killer/T-Cell Lymphoma Diagnosed Between 2000
and 2013: A Cooperative Study in Japan. J Clin Oncol 35(1):32-39, 2017.
20170380
Yasuo M, Kitaguchi Y, Komatsu Y, Hama
M, Koizumi T, Agatsuma T, Ichiyama T, Kato A, Moteki
H, Hanaoka M : Self-assessment of Allergic Rhinitis andAsthma (SACRA) Questionnaire-based Allergic Rhinitis
Treatment Improves Asthma Control in Asthmatic Patientswith Allergic Rhinitis. Intern Med 56(1): 31-39, 2017.

Infection and Host Defense
20170381
M o r o d a M , Ta k a m o t o M , I w a k u r a Y,
Nakayama J, Aosai F : Interleukin-17A-deficient mice arehighly susceptible to Toxoplasma gondii infection due toexcessively induced T. gondii HSP70 and interferon gamma
production. Infect Immun 85: e00399-17, 2017.

Brain Disease Research
20170382
Fukami Y, Ariga T, Yamada M, Yuki N : Brain
Gangliosides in Alzheimer's Disease: Increased Expressionof Cholinergic Neuron-Specific Gangliosides. Curr
Alzheimer Res 14: 586-591, 2017.
20170383
Kano Y, Kodaira M, Ushiki A, Kosaka M,
Yamada M, Shingu K, Nishihara H, Hanaoka M, Sekijima Y: The Complete Remission of Acquired Immunodeficiency
Syndrome-associated Isolated Central Nervous System
Lymphomatoid Granulomatosis: A Case Report and Reviewof the Literature. Intern Med 56: 2497-2501, 2017.
20170384
Oyanagi K, Kinoshita M, Suzuki-Kouyama
E, Inoue T, Nakahara A, Tokiwai M, Arai N, Satoh J, Aoki
N, Jinnai K, Yazawa I, Arai K, Ishihara K, Kawamura M,
Ishizawa K, Hasegawa K, Yagisita S, Amano N, Yoshida K,
Terada S, Yoshida M, Akiyama H, Mitsuyama Y, Ikeda S :Adult onset leukoencephalopathy with axonal spheroids andpigmented glia (ALSP) and Nasu-Hakola disease: Lesion
staging and dynamic changes of axons and microglial
subsets. Brain Pathol 27: 748-769, 2017.
20170385
Shintaku M, Kaneda D, Oyanagi K :Novel intracytoplasmic inclusions immunoreactive forphosphorylated-TDP43 and cystatin C in anterior horncells in a case of sporadic amyotrophic lateral sclerosis.

Neuropathology 37: 526-534, 2017.
20170386
Takei Y, Koshihara H, Oguchi K, Oyanagi K,
Ohara S : An autopsy case of respiratory failure induced
by repetitive cervical spinal cord damage due to abnormal
movement of the neck in athetoid cerebral palsy. Intern Med
56: 1425-1430, 2017.
20170387
Yoshida K, Hayashi H, Wakusawa S, Shigemasa
R, Koide R, Ishikawa T, Tatsumi Y, Kato K, Ohara S,
Ikeda S : Coexistence of copper in the iron-rich particles ofaceruloplasminemia brain. Biol Trace Ele Res 175: 79-86,2017.
20170388
Konno T, Yoshida K, Mizuno T, Kawarai
T, Tada M, Nozaki H, Ikeda S, Nishizawa M, Onodera
O, Wszolek ZK, Ikeuchi T : Clinical and genetic
characterization of adult-onset leukoencephalopathy withaxonal spheroids and pigmented glia associated with CSF1R
mutation. Eur J Neurol 24: 37-45, 2017.
20170389
Nakamura K, Yoshida K, Matsushima A,
Shimizu Y, Sato S, Yahikozawa H, Ohara S, Yazawa
M, Ushiyama M, Sato M, Morita H, Inoue A, Ikeda S :Natural history of spinocerebellar ataxia type 31: a 4-year
prospective study. Cerebellum 16: 518-524, 2017.
20170390
Satake T, Yamashita K, Hayashi K, Miyatake
S, Tamura-Nakano M, Doi H, Furuta Y, Shioi G, Miura E,
Takeo YH, Yoshida K, Yahikozawa H, Matsumoto N, Yuzaki
M, Suzuki A : MTCL1 plays an essential role in maintaining
Purkinje neuron axon initial segment. EMBO J 36: 12271242, 2017.
20170391
Matsushima A, Yoshida K, Genno H, Ikeda S :Principal component analysis for ataxic gait using a triaxial
accelerometer. J NeuroEng Rehabili 14: 37, 2017.
20170392
Yoshida K, Matsushima A, Nakamura K :Inter-generational instability of inserted repeats duringtransmission in spinocerebellar ataxia type 31. J Hum Genet
62: 923-925, 2017.
20170393
Yoshinaga T, Nakamura K, Ishikawa M,
Yamaguchi T, Takano K, Wakui K, Kosho T, Yoshida K,
Fukushima Y, Sekijima Y : A novel frameshift mutationof SYNE1 in a Japanese family with autosomal recessive
cerebellar ataxia type 8. Hum Genome Var 4: 17052, 2017.

Innovation of Medical and Health Sciences
Research
20170394

Takahashi R, Kobayashi M, Sasaki T, Yokokawa

28Y, Momose H, Ohhashi T : Driving simulation test forevaluating hazard perception: Elderly driver response
characteristics. Transp Res Part F Traffic Psychol Behav 49:
257-270, 2017.
20170395
Nizamutdinova IT, Maejima D, Nagai T,
Meininger CJ, Gashev AA : Histamine as an EndotheliumDerived Relaxing Factor in Aged Mesenteric Lymphatic
Vessels. Lymphat Res Biol 15(2): 136-145, 2017.

Drug Discovery Science20170396
Sasayama D, Sugiyama N, Yonekubo S, Pawlak
A, Murasawa H, Nakamura M, Hayashi M, Ogawa T, Moro
M, Washizuka S, Amano N, Hongo K, Ohnota H : Noveloestrogen receptor β-selective ligand reduces obesity anddepressive-like behaviour in ovariectomized mice. Sci Rep
7: 4663, 2017.

Hearing Implant Sciences
20170397
Noguchi Y, Fukuda S, Fukushima K, Gyo K,
Hara A, Nakashima T, Ogawa K, Okamoto M, SatoH, Usami
SI, Yamasoba T, Yokoyama T, Kitamura K : A nationwide
study on enlargement of the vestibular aqueduct in Japan.
Auris Nasus Larynx 44(1): 33-39, 2017.
20170398
Okada M, Hato N, Nishio SY, Kitoh R, Ogawa
K, Kanzaki S, Sone M, Fukuda S, Hara A, Ikezono T,
Ishikawa K, Iwasaki S, Kaga K, Kakehata S, Matsubara A,
Matsunaga T, Murata T, Naito Y, Nakagawa T, Nishizaki
K, Noguchi Y, Sano H, Sato H, Suzuki M, Shojaku H,
Takahashi H, Takeda H, Tono T, Yamashita H, Yamaso : The
effect of initial treatment on hearing prognosis in idiopathic
sudden sensorineural hearing loss: a nationwide survey inJapan. Acta Otolaryngol 137(sup565): S30-S33, 2017.
20170399
Iki T, Tanaka M, Kitajiri SI, Kita T, Kawasaki
Y, Mizukoshi A, Fujibuchi W, nakagawa T, Nakahara T, Ito
J, Omori K, Saito MK : Microarray analyses of otospheres
derived from the cochlea in the inner ear identify putativetranscription factors that regulate the characteristics ofotospheres. PLoS ONE 12(6): e0179901, 2017.
20170400
Kitano T, Miyagawa M, Nishio SY, Moteki H,
Oda K, Ohyama K, Miyazaki H, Hidaka H, Nakamura KI,
Murata T, Matsuoka R, Ohta Y, Nishiyama N, Kumakawa
K, Furutate S, Iwasaki S, Yamada T, Ohta Y, Uehara N,
Noguchi Y, Usami SI : POU4F3 mutation screening inJapanese hearing loss patients: Massively parallel DNA
sequencing-based analysis identified novel variants
associated with autosomal dominant hearing loss. PLoS
ONE 12(5): e0177636, 2017.

20170401
Kitoh R, Nishio SY, Ogawa K, kanzaki S, Hato
N, Sone M, Fukuda S, Hara A, Ikezono T, Ishikawa K,
Iwasaki S, Kaga K, Kakehata S, Matsubara A, Matsunaga
T, Murata T, Naito Y, Nakagawa T, Nishizaki K, Noguchi Y,
Sano H, Sato H, Sato H, Suzuki M, Shojaku H, Takahashi
H, Takeda H, Tono T, Yamashita H, Yamasoba T, Usami SI: Nationwide epidemiological survey of idiopathic sudden
sensorineural hearing loss in Japan. Acta Otolaryngol
137(sup565): S8-S16, 2017.
20170402
Yoshida T, Sone M, Kitoh R, Nishio SY,
Ogawa K, Kanzaki S, Hato N, Fukuda S, Hara A, Ikezono
T, Ishikawa K, Iwasaki S, kaga K, kakehata S, Matsubara
A, Matsunaga T, Murata T, Naito Y, Nakagawa T, Nishizaki
K, Noguchi Y, Sano H, Sato H, Suzuki M, Shojaku H,
Takahashi H, Takeda H, Tono T, Yamashita H, Yamasoba T,
Usami SI : Idiopathic sudden sensorineural hearing loss andacute low-tone sensorineural hearing loss: a comparison of
the results of a nationwide epidemiological survey in Japan.
Acta Otolaryngol 137(sup565): S38-S59, 2017.
20170403
Umesawa M, Kobashi G, Kitoh R, Nishio SY,
Ogawa K, Hato N, Sone M, Fukuda S, Hara A, Ikezono T,
Ishikawa K, Iwasaki S, Kaga K, Kakehata S, Matsubara A,
Matsunaga T, Murata T, Naito Y, Nakagawa T, Nishizaki
K, Noguchi Y, Sano H, Sato H, Suzuki M, Shojaku H,
Takahashi H, Takeda H, Tono T, Yamashita H, Yamasoba
T, Usami SI : Relationships among drinking and smoking
habits, history of diseases, body mass index and idiopathic
sudden sensorineural hearing loss in Japanese patients. Acta
Otolaryngol 137(sup565): S17-S23, 2017.
20170404
Sato H, Kuwashima S, Nishio SY, Kitoh R,
Fukuda S, Hara A, Hato N, Ikezono T, Ishikawa K, Iwasaki
S, Kaga K, Matsubara A, Matsunaga T, Murata T, Naito Y,
Nakagawa T, Nishizaki K, Noguchi Y, Ogawa K, Sano H,
Sone M, Shojaku H, Takahashi H, Tono T, Yamashita H,
Yamasoba T, Usami SI : Epidemiological survey of acutelow-tone sensorineural hearing loss. Acta Otolaryngol
137(sup565): S34-S37, 2017.

Aging Biology
20170405
Xu Z, Huo J, Ding X, Yang M, Li L, Dai J,
Hosoe K, Kubo H, Mori M, Higuchi K : Coenzyme Q10
improves lipid metabolism and ameliorates obesity by
regulating CaMKII-mediated PDE4 inhibition. Sci Rep 7:8253, 2017.
20170406
Li L, Sawashita J, Ding X, Yang M, Xu Z,
Miyahara H, Mori M, Higuchi K : Caloric restriction reduces
the systemic progression of mouse AApoAII amyloidosis.
PLoS ONE 12: e0172402, 2017.

29

20170407
Yang M, Liu Y, Li L, Miyahara H, Ding X, Dai
J, Sawashita J, Mori M, Higuchi K : Apolipoprotein A-II
accelerates reactive AA amyloidosis. Amyloid 24(sup1):
147-148, 2017.
20170408
Sawashita J, Li L, Liu Y, Ding X, Yang M, Xu
Z, Higuchi K : Caloric restriction prevents the progression ofmurine AApoAII amyloidosis. Amyloid 24(sup1): 171-172,
2017.
20170409
Akiguchi I, Pallas M, Bubka H, Akiyama H,
Ueno M, Han J, Yagi H, Nishikawa T, Chiba Y, Sugiyama H,
Takahashi R, Unno K, Higuchi K, Hosokawa M : SAMP8
mice as a neuropathological model of accelerated brain
aging and dementia: Toshio Takeda's legacy and future
directions. Neuropathology 37: 293-305, 2017.
20170410
Yoshinaga T, Yazaki M, Kametani F, Sekijima
Y, Iesato Y, Miyahara T, Tsuchiya-Suzuki A, Sano K,
Higuchi K, Ikeda SI : Marked biochemical differencein amyloid proportion beteween intra- and extraocular
tissues in a liver-transplanted patient with hereditary ATTR
amyloidosis. Amyloid 24: 17-23, 2017.

Histochem Cell Biol 148: 463-471, 2017.
20170416
Yo s h i z a w a J , I s h i z o n e S , I k e y a m a M ,Nakayama J : Gastric hepatoid adenocarcinoma resulting ina spontaneous gastric perforation: a case report and reviewof the literature. BMC Cancer 17: 368, 2017.
20170417
Ohya A, Yamanoi K, Shimojo H, Fujii C,
Nakayama J : Gastric gland mucin-specific O-glycan
expression decreases with tumor progession from presursor
lesions to pancreatic cancer. Cancer Sci 108: 1897-1902,
2017.
20170418
Moroda M, Takamoto M, Iwakura Y, Nakayama
J, Aosai F : IL17A-deficient mice are highly susceptible toToxoplasma gondii infection due to excessively induced
T. gondii HSP70 and IFN-γ production. Infect Immun 85:
e00399-17, 2017.

Metabolic Regulation
20170419
Tanaka N, Aoyama T, Kimura S, Gonzalez FJ: Targeting nuclear receptors for the treatment of fatty liverdisease. Pharmacol Ther 179: 142-157, 2017.

Neuroplasticity
20170411
Shirai Y, Li W, Suzuki T : Role of Splice
Variants of Gtf2i, a Transcription Factor Localizing at
Postsynaptic Sites, and Its Relation to NeuropsychiatricDiseases. Int J Mol Sci 18: 411, 2017.
20170412
Guo W, Liu Q, Suzuki T : Protein componentsof the backbone structure of PSDs of type I excitatory
synapses. Shinshu Med J 65: 211-224, 2017.

Molecular Pathology
20170413
Li X, Kurita H, Xiao T, Iijima K, Kurashina K,
Nakayama J : Potential involvement of chondroitin sulfate A
in the pathogenesis of ameloblastoma. Acta Histochem 119:439-445, 2017.
20170414
Chambers JK, Saito T, Fukushima K, Kakuta S,
Nakayama J, Ohno K, Tsujimoto H, Nakayama H, Uchida K: Adenocarcinoma of Barrett’s esophagus in a dog. J Toxicol
Pathol 30: 239-243, 2017.
20170415
Kawakubo M, Horiuchi K, Komura H, Sato Y,
Kato M, Ikeyama M, Fukushima M, Yamada S, Ishizone
S, Matsumoto T, Ota H, Sagara J, Nakayama J : Cloningof Helicobacter suis cholesterol α-glucosyltransferase
and production of an antibody capable of detecting it informalin-fixed, paraffin-embedded gastric tissue sections.

20170420
Tanaka N, Takahashi S, Hu X, Lu Y, Fujimori
N, Golla S, Fang ZZ, Aoyama T, Krausz KW, Gonzalez FJ: Growth arrest and DNA damage-inducible 45α protects
against nonalcoholic steatohepatitis induced by methionineand choline-deficient diet. Biochim Biophys Acta 1863:
3170-3182, 2017.
20170421
Hu X, Tanaka N, Guo R, Lu Y, Nakajima T,
Gonzalez FJ, Aoyama T : PPARα protects against transfatty-acid-containing diet-induced steatohepatitis. J Nutr
Biochem 39: 77-85, 2017.
20170422
K i t a b a t a k e H , Ta n a k a N , F u j i m o r i N ,Komatsu M, Okubo A, Kakegawa K, Kimura T, Sugiura A,
Yamazaki T, Shibata S, Ichikawa Y, Joshita S, Umemura T,
Matsumoto A, Koinuma M, Sano K, Aoyama T, Tanaka E :Association between endotoxemia and histological featuresof nonalcoholic fatty liver disease. World J Gastroenterol 23:
712-722, 2017.
20170423
Nakajima T, Yang Y, Lu Y, Kamijo Y, Yamada
Y, Nakamura K, Koyama M, Yamaguchi S, Sugiyama E,
Tanaka N, Aoyama T : Decreased fatty acid β-oxidation is
the main cause of fatty liver induced by polyunsaturated
fatty acid deficiency in mice. Tohoku J Exp Med 242: 229239, 2017.
20170424

Kimura T, Kobayashi A, Tanaka N, Sano K,

30

Komatsu M, Fujimori N, Yamazaki T, Shibata S, Ichikawa
Y, Joshita S, Umemura T, Matsumoto A, Horiuchi A,
Mori H, Wada S, Kiyosawa K, Miyagawa SI, Tanaka
E : Clinicopathological characteristics of non-B non-C
hepatocellular carcinoma without past hepatitis B virus
infection. Hepatol Res 47: 405-418, 2017.
20170425
Kimura T, Shinji A, Tanaka N, Koinuma M,
Yamaura M, Nagaya T, Joshita S, Komatsu M, Umemura T,
Horiuchi A, Wada S, Tanaka E : Association between lower
air pressure and the onset of ischemic colitis: a case-control
study. Eur J Gastroenterol Hepatol 29: 1071-1078, 2017.
20170426
Fang ZZ, Tanaka N, Lu D, Jiang CT, Zhang
WH, Zhang C, Du Z, Fu ZW, Gao P, Cao YF, Sun HZ, Zhu
ZT, Cai Y, Krausz KW, Yao Z, Gonzalez FJ : Role of thelipid-regulated NF-κB/IL-6/STAT3 axis in alpha-naphthyl
isothiocyanate-induced liver injury. Arch Toxicol 91: 22352244, 2017.

Tanaka E : Development of diffuse large B-cell lymphoma
from follicular lymphoma of the duodenum: changes inendoscopic findings during a 6-year follow-up. Clin J
Gastroenterol 10: 79-85, 2017.
20170433
Fujimori N, Komatsu M, Tanaka N, Iwaya
M, Nakano H, Sugiura A, Yamazaki T, Shibata S, Iwaya
Y, Muraki T, Ichikawa Y, Kimura T, Joshita S, Umemura
T, Matsumoto A, Tanaka E : Cimetidine/lactulose therapy
ameliorates erythropoietic protoporphyria-related liver
injury. Clin J Gastroenterol 10: 452-458, 2017.
20170434
Sugiura A, Wada S, Mori H, Kimura T, Matsuda
Y, Tanaka N, Tanaka E, Kiyosawa K : Successful treatment
for chronic hepatitis C-autoimmune hepatitis overlap
syndrome due to daclatasvir and asunaprevir. Case Rep
Gastroenterol 11: 305-311, 2017.

Cardiovascular Research

20170427
Takahashi S, Tanaka N, Golla S, Fukami T,
Krausz KW, Polunas MA, Weig BC, Masuo Y, Xie C, Jiang
C, Gonzalez FJ : Farnesoid X receptor protects against lowdose carbon tetrachloride-induced liver injury through thetaurocholate-JNK pathway. Toxicol Sci 158: 334-346, 2017.

20170435
Yamauchi A, Kamiyoshi A, Koyama T, Iinuma
N, Yamaguchi S, Miyazaki H, Hirano E, Kaku T, Shindo T: Placental extract ameliorates non-alcoholic steatohepatitis(NASH) by exerting protective effects on endothelial cells.
Heliyon 3: e00416, 2017.

20170428
Wang H, Fang ZZ, Meng R, Cao YF, Tanaka N,
Krausz KW, Gonzalez FJ : Glycyrrhizin and glycyrrhetinicacid inhibits alpha-naphthyl isothiocyanate-induced liver
injury and bile acid cycle disruption. Toxicology 386: 133142, 2017.

20170436
Liu T, Kamiyoshi A, Sakurai T, IchikawaShindo Y, Kawate H, Yang L, Tanaka M, Xian X, Imai A,
Zhai L, Hirabayashi K, Dai K, Tanimura K, Liu T, Cui N,
Igarashi K, Yamauchi A, Shindo T : Endogenous calcitonin
gene-related peptide regulates lipid metabolism and energy
homeostasis in male mice. Endocrinology 158: 1194-1206,
2017.

20170429
Maruyama M, Tanaka N, Kubota D, Miyajima
M, Kimura T, Tokutake K, Imai R, Fujisawa T, Mori H,
Matsuda Y, Wada S, Horiuchi A, Kiyosawa K : Vonoprazanbased regimen is more useful than PPI-based one as a firstline Helicobacter pylori eradication: a randomized controlled
trial. Can J Gastroenterol Hepatol 2017: 4385161, 2017.
20170430
Koyama M, Ogasawara Y, Endou K, Akano H,
Nakajima T, Aoyama T, Nakamura K : Fermentation-inducedchanges in the concentrations of organic acids, amino acids,
sugars, and minerals and superoxide dismutase-like activity
in tomato vinegar. Int J Food Prop 20: 888-898, 2017.
20170431
Yamazaki T, Ochi Y, Tanaka N, Watanabe
T, Iwaya Y, Seki A, Hara E, Tanaka E, Watanabe T, Imai
S, Hasebe O : Massive ascites caused by intra-pancreatic
arterioportal fistula: a rare complication of chronicpancreatitis. Clin J Gastroenterol 10: 73-78, 2017.
20170432
Kitabatake H, Nagaya T, Tanaka N, Ota H,
Sano K, Asano N, Suga T, Nakamura Y, Akamatsu T,

20170437
Imai A, Toriyama Y, Iesato Y, Hirabayashi K,
Sakurai T, Kamiyoshi A, Ichikawa-Shindo Y, Kawate H,
Tanaka M, Liu T, Xian X, Zhai L, Dai K, Tanimura K, Liu T,
Cui N, Yamauchi A, Murata T, Shindo T : Adrenomedullin
suppresses vascular endothelial growth factor-induced
vascular hyperpermeability and inflammation in retinopathy.
Am J Pathol 187: 999-1015, 2017.
20170438
Xian X, Sakurai T, Kamiyoshi A, IchikawaShindo Y, Tanaka M, Koyama T, Kawate H, Yang L, Liu T,
Imai A, Zhai L, Hirabayashi K, Dai K, Tanimura K, Liu T,
Cui N, Igarashi K, Yamauchi A, Shindo T : Vasoprotective
activities of the adrenomedullin-RAMP2 system inendothelial cells. Endocrinology 158: 1359-1372, 2017.
20170439
Sakurai T, Shindo T, Sato M : Noninheritablematernal factors usefurl for genetic manipulation in
mammals. In: Kloc M. Oocytes, Maternal information andfunctions. Berlin : Springer; 2017. p.495-510.

31

neuroblastoma. Transfus Apher Sci 56: 445-447, 2017.

Sports Medical Sciences
20170440
Masuki S, Nishida K, Hashimoto S, Morikawa
M, Takasugi S, Nagata M, Taniguchi S, Rokutan K, Nose
H : Effects of milk product intake on thigh muscle strengthand NFKB gene methylation during home-based interval
walking training in older women: a randomized, controlled
pilot study. PLoS ONE 12: e0176757, 2017.
20170441
Ogawa Y, Kamijo Y, Ikegawa S, Masuki S,
Nose H : Effects of postural change from supine to headup tilt on the skin sympathetic nerve activity component
synchronised with the cardiac cycle in warmed men. J
Physiol 595: 1185-1200, 2017.

20170449
Fujihara I, Yanagisawa R, Sato R, Kitazawa N,
Sakashita K : Ocular and nasal symptoms prior to acute skingraft-versus-host disease. Pediatr Int 59: 833-834, 2017.

Rehabilitation Center
20170450
Yamamoto S, Matsunaga A, Takaaki I, Misawa
K, Yamazaki S, Higuchi S, Ohira M : Exercise-based cardiac
rehabilitation for elderly patients with coronary arterydisease. JSM Physical Med Rehabil 1: 1003, 2017.

20170442
Masuki S, Morikawa M, Nose H : Interval
walking training can increase physical fitness in middle-aged
and older people. Exerc Sport Sci Rev 45: 154-162, 2017.

20170451
Matsuzawa R, Hoshi K, Yoneki K, Harada
M, Watanabe T, Shimoda T, Yamamoto S, Matsunaga A :Effectiveness of Exercise Training on Exercise Tolerance,
Physical Function, and Quality of Life in Elderly People
Undergoing Hemodialysis: a Systematic Review and Metaanalysis. Kidney Int Rep 2: 1096-1110, 2017.

20170443
H o r i u c h i M , E n d o J , K o n d o K , U n o T,
Morikawa M, Nose H : Impact of carbohydrate-electrolyte
beverage ingestion on heart rate response while climbing
Mt.Fuji at ~3000m. Biomed Res Int 2017: 3919826, 2017.

20170452
Yamaga T, Yamamoto S, Matsumori K : The
Impact of Physical Activity on Cancer Prevention andSurvivorship. Phys Med Rehabil Res 2: DOI: 10.15761/
PMRR.1000138, 2017.

Radiology Division

20170453
Nishie K, Yamamoto S, Nagata C, Koizumi T,
Hanaoka M : Anamorelin for advanced non-small-cell lungcancer with cachexia: systematic review and meta-analysis.
Lung Cancer 112: 25-34, 2017.

20170444
Kanazawa T, Ohkubo M, Kondo T, Miyazawa
T, Inagawa S : Improved wedge method for the measurementof sub-millimeter slice thicknesses in magnetic resonanceimaging. Radiol Phys Technol 10: 446-453, 2017.

Blood Transfusion Center
20170445
Yanagisawa R, Abe S, Fujihara I, Komori K,
Kondo Y, Sakashita K, Nakamura T : Transfusion-associatedhypoxemia in pediatric patients with solid tumors after
autologous peripheral blood stem cell transplantation.
Transfus Apher Sci 56: 744-747, 2017.
20170446
Yanagisawa R, Ogiso Y, Yoshikawa K, Tanaka
M, Matsuda K, Ishii E : Myelomonocytic differentiation
associated with NPM1-RARA rearrangement. Br J Haematol
179: 183, 2017.

20170454
Yamamoto S, Yamaga T, Nishie K, Nagata C,
Mori R : Positive airway pressure for heart failure associatedwith central sleep apnoea (Protocol). Cochrane Database
Syst Rev 2017(9): CD012803, 2017.

Center for Medical Genetics
20170455
Takano K, Goto K, Motobayashi M, Wakui K,
Kawamura R, Yamaguchi T, Fukushima Y, Kosho T : Early
manifestations of epileptic encephalopathy, brain atrophy,
and elevation of serum neuron specific enolase in a boy withbeta-propeller protein-associated neurodegeneration. Eur J
Med Genet 60: 521-526, 2017.

20170447
Yanagisawa R, Minami K, Kubota N, Iwade T,
Ogiso Y : Asymptomatic subcutaneous cervical mass due
to Actinomyces odontolyticus infection in a pyriform sinus
fistula. Pediatr Int 59: 941-942, 2017.

20170456
Yoshinaga T, Nakamura K, Ishikawa M,
Yamaguchi T, Takano K, Wakui K, Kosho T, Yoshida K,
Fukushima Y, Sekijima Y : A novel frameshift mutationof SYNE1 in a Japanese family with autosomal recessive
cerebellar ataxia type 8. Hum Genome Var 4: 17052, 2017.

20170448
Yanagisawa R, Fujihara I, Komori K, Abe
S, Ono T, Sakashita K, Nakamura T : Transfusionassociated circulatory overload in a pediatric patient with

20170457
Morikawa M, Takano K, Motobayashi M, Shiba
N, Kosho T, Nakazawa Y, Inaba Y : Clinical features ofa female with WDR45 mutation complicated by infantile

32

spasms: a case report and literature review. Brain Dev 39:
804-807, 2017.
20170458
Mizumoto S, Kosho T, Hatamochi A, Honda T,
Yamaguchi T, Okamoto N, Miyake N, Yamada S, Sugahara
K : Defect in dermatan sulfate in urine of patients with
Ehlers-Danlos syndrome caused by a CHST14/D4ST1
deficiency. Clin Biochem 50: 670-677, 2017.
20170459
Yoshinaga T, Yazaki M, Kametani F, Sekijima
Y, Iesato Y, Miyahara T, Tsuchiya-Suzuki A, Sano K,
Higuchi K, Ikeda SI : Marked biochemical difference inamyloid proportion between intra- and extraocular tissues
in a liver-transplanted patient with hereditary ATTR
amyloidosis. Amyloid 24: 17-23, 2017.
20170460
Yoshinaga T, Yazaki M, Ohno M, Kodama S,
Koyama J, Sekijima Y : Cardiac Amyloidosis AssociatedWith Amyloidogenic Transthyretin V122I Variant in an
Elderly Japanese Woman. Circ J 81: 893-894, 2017.
20170461
F u k u s h i m a H , S h i m i z u K , Wa t a h i k i A ,Hoshikawa S, Kosho T, Oba D, Sakano S, Arakaki M,
Yamada A, Nagashima K, Okabe K, Fukumoto S, Jimi
E, Bigas A, Nakayama KI, Nakayama K, Aoki Y, Wei W,
Inuzuka H : NOTCH2 Hajdu-Cheney Mutations Escape
SCFFBW7-Dependent Proteolysis to Promote Osteoporosis.
Mol Cell 68: 645-658, 2017.
20170462
Fukuda Y, Higuchi Y, Shinozaki K, Tanigawa Y,
Abe T, Hanaoka N, Matsubayashi S, Yamaguchi T, Kosho
T, Nakamichi K : Mobile Cecum in a Young Woman with
Ehlers-Danlos Syndrome Hypermobility type: A Case Reportand Review of the Literature. Intern Med 56: 2791-2796,
2017.
20170463
Uehara M, Nakamura Y, Takahashi J, Kamimura
M, Ikegami S, Suzuki T, Uchiyama S, Yamaguchi T, Kosho
T, Kato H : Efficacy of Denosumab for Osteoporosis in
Three Female Patients with Osteogenesis Imperfecta.
Tohoku J Exp Med 242: 115-120, 2017.
20170464
Oba H, Takahashi J, Takano K, Inaba Y,
Motobayashi M, Nishimura G, Kuraishi S, Shimizu M,
Ikegami S, Futatsugi T, Uehara M, Kosho T, Kato H,
Uno K : Rigid Occipitocervical Instrumented Fusion for
Atlantoaxial Instability in an 18-Month-Old Toddler With
Brachytelephalangic Chondrodysplasia Punctata: A Case
Report. Spine (Phila Pa 1976) 42: E1380-E1385, 2017.

Center for Clinical Research
20170465

Sano K, Asahina M, Uehara T, Matsumoto K,

Araki N, Okuyama R : Degranulation and shrinkage of darkcells in eccrine glands and elevated serum carcinoembryonicantigen in patients with acquired idiopathic generalized
anhidrosis. J Eur Acad Dermatol Venereol 31: 2097-2103,
2017.

Intractable Diseases Care Center
20170466
Ikeda S : Localized amyloidogenic
immunoglobulin light chain-derived amyloidosis in a young
boy and an adolescent girl. Amyloid 24: 138-140, 2017.
20170467
Ozawa K, Hineno A, Kinoshita T, Ishihara
S, Ikeda S : Suspected adverse effects after humanpapillomavirus vaccination: A temporal relationship between
vaccine administration and the appearance of symptoms inJapan. Drug Saf 40: 1219-1229, 2017.

Advence Center for Cellular Therapy
20170468
Koya T, Yanagisawa R, Higuchi Y, Sano K,
Shimodaira S : Interferon-α-inducible Dendritic Cells
Matured with OK-432 Exhibit TRAIL and Fas Ligand
Pathway-mediated Killer Activity. Sci Rep 7: 42145, 2017.
20170469
Koido S, Okamoto M, Kobayashi M,
Shimodaira S, Sugiyama H : Significance of Wilms' tumor
1 antigen as a cancer vaccine for pancreatic cancer. Discov
Med 24: 41-49, 2017.
20170470
Sakai K, Shimodaira S, Maejima S, Sano K,
Higuchi Y, Koya T, Sugiyama H, Hongo K : Clinical effectand immunological response in patients with advanced
malignant glioma treated with WT1-pulsed dendritic cellbased immunotherapy: A report of two cases. Interdiscip
Neurosurg 9: 24-29, 2017.

Department of Pharmacy
20170471
Watanabe K, Honda G, Miyagi T, Kanai M,
Usami N, Yamaori S, Iwamuro Y, Chinaka S, Aramaki
H, Yamamoto I : The Duquenois reaction revisited: mass
spectrometric estimation of chromophore structures derived
from major phytocannabinoids. Forensic Toxicol 35: 185189, 2017.
20170472
Yamaori S, Jiang R, Maeda C, Ogawa R,
Okazaki H, Aramaki H, Watanabe K : Expression levels of
39 Cyp mRNAs in the mouse brain and neuroblastoma celllines, C-1300N18 and NB2a – strong expression of Cyp1b1.
Fundam Toxicol Sci 4: 195-200, 2017.
20170473

Kim J-H, Yamaori S, Tanabe T, Takagi M,

33

Matsubara T, Okamoto M, Kimura S, Gonzalez FJ : Lack ofepithelial PPARγ causes cystic adenomatoid malformations
in mouse fetal lung. Biochem Biophys Res Commun 491:
271-276, 2017.

35

補

遺
No．45
2016

37

Preventive Medicine and Public Health20160462
Grosse Y, Loomis D, Guyoton KZ, El Ghissassi
F, Bonvard V, Bembrahim-Tallaa L, Mattock H, Straif K;
International Agency for Research on Cancer MonographWorking Group : Carcinogenicity of some industrial
chemicals. Lancet Oncol 17: 419-420, 2016.

Internal Medicine 2
20160463
Kawakami T, Hirabayashi Y, Kawakami F,
Isobe R, Kaneko N, Mimura Y, Ito T, Furuta K, Shimazaki
M, Nakazawa H, Kitano K : Persistent Infection of Drugresistant Influenza A Virus during Chemotherapy for
Malignant Lymphoma. Intern Med 55: 1807-1810, 2016.
20160464
Nakanuma Y, Ishizu Y, Zen Y, Harada K,
Umemura T : Histopathology of IgG4-Related Autoimmune
Hepatitis and IgG4-Related Hepatopathy in IgG4-RelatedDisease. Semin Liver Dis 36: 229-241, 2016.
20160465
Shibata S, Joshita S, Umemura T, Yamazaki
T, Fujimori N, Ichikawa Y, Komatsu M, Matsumoto A,
Tanaka E : Liver stiffness-spleen size-to-platelet ratio risk
score detects esophageal varices in chronic liver disease.
Springerplus 5: 998, 2016.

信大
州学
大医
学学
医部
学業
部績
業録
績編
録集
編要
集項
要（
項抜粋）
信州

あ

（平成28年12月29日改正）

１．収録対象 ２．収録対象
 信州大学医学部医学科・大学院医学系研究科・医学部附属病院及び出版委員会で信州大学医学部医学科・大学院医学系研究科・医学部附属病院及び出版委員会で認めた施設等に所属する者（当該年に在籍した者全員）認めた施設等に所属する者（当該年度に在籍した者全員）
２．収録内容 ３．収録内容
収録対象は、本文が欧文で執筆された研究業績とし、次の３項目に分ける。
研究業績を次の２項目に分ける。
１）論文
１）論文
原著、綜説、展望、症例報告、速報、予報で、査読のある学術雑誌に発表のもの。
原著、綜説、展望、症例報告、速報、予報で学術雑誌に発表のもの。
学術集会記録（全国的又は世界的規模の集会記録で、原著論文と同様の内容をも
学術集会記録（全国的又は世界的規模の集会記録で、原著論文と同様の内容をもち、ち、別刷が発行されているもの）
別刷が発行されているもの）
２）著書
２）著書
単行書、分担執筆。
単行書、分担執筆。
３）その他
治療指針、トピックス、事典等、専門的知見にもとづき執筆された、論文形式の
ただし、以下のものは除外する。
記事（イ）学会発表の抄録（邦文、欧文を問わない。論文型式をとっていても学会発表に関するもの及び１頁ものの速報は抄録とみなす）
ただし、以下のものは除外する。
（ロ）セミナー、シンポジウム、その他の講演のテキストないし記録。
（イ）学会発表の抄録（邦文、欧文を問わない。論文型式をとっていても学会発表（ハ）業務報告書（文部科学省、厚生労働省、その他助成機関への研究報告書）
に関するもの及び１頁ものの速報は抄録とみなす）（ニ）座談会記事。
（ロ）セミナー、シンポジウム、その他の講演のテキストないし記録。
（ホ）学会記。
務報告書（文部科学省、厚生労働省、その他助成機関への研究報告書）（ハ）業and（ヘ）質疑応答（ＱＡ）、治療指針、問題集の解説、トピックス、話題、グラビア、
（ニ）
座
談会記事。
事典等に類するもの。
（ホ）学会記。
（ト）新聞記事、教育に関する記事、人物紹介、書評、随筆など学術性が認められ（ヘ）論文形式をとらない質疑応答（Q and A）、問題集の解説、話題、グラビア等ないもの。
に類するもの。
（チ）著者表示が団体名で個人の著者性が認められないもの。
（ト）新聞・週刊誌記事、教育に関する記事、人物紹介、書評、随筆など学術性が（リ）学術雑誌とは認められないものに発表したもの。
認められないもの。
（ヌ）訳本及び訳論文。
（チ）著者表示が団体名で個人の著者性が認められないもの。
４．収録期間
毎年１月～12月とがき

信州大学医学部医学科
・大学院医学系研究科・医学部附属病院業績録第46号をお届けします。
信州大学医学部医学科・大学院医学系研究科・医学部附属病院業績録第38 号をお届けします。
本業績録は過去１年間、各教室や部門などでなされた４つの活動（研究活動、教育活動、診本業績録は過去１年間、各講座や部門等でなされた４つの活動（研究、教育、診療、社会貢献）
療活動、社会貢献）のうち、研究活動の成果として公表された論文を中心にまとめたものです。
のうち、研究活動の成果として公表された論文を中心にまとめたものです。自己点検、自己評
自己点検、自己評価、学内・学外への報告において、本業績録の役割は重要と思われます。この１年の研究活動を振り返り、今後の方向性を考える契機にしていただければ幸いです。
価、学内外への報告において、本業績録の果たす役割は重要と思われます。このような観点から、
この１年間の研究活動を振り返り、今後の方向性等を考える契機にしていただけたら幸いに存
昨今、高額の掲載料を徴収し、レビューなしで科学的妥当性・信頼性を問わずに論文を掲載
じます。
するオープンアクセス誌「ハゲタカジャーナル」が横行していることは皆さまもよくご存じのことと思います。「ハゲタカジャーナル」の問題は、医師・研究者の間だけでなく一般のメディアにも取り上げられるようになり、2018年12月には文部科学大臣が「大変深刻な事態」と懸
今年度の英文論文総数は昨年度より微減し、90 年度以降で最も少ない 386 という結果となり念を表明するに至っています。それを受けて全国の大学や研究機関でも一斉にこの問題が議題ました。しかしながら、単なる総数のみの評価が必ずしも適切であるとは言えず、今年度の業に挙げられ、今後「ハゲタカジャーナル」を業績に加えた場合、業績がマイナス査定される可能性も示唆されています。信州大学でも「ハゲタカジャーナル」を如何に見極めるかが話し合
績の中には極めて質の高い研究成果も少なくありません。今日、卒業生の大学離れや医学科入われているところです。
学定員数増加等により、診療や教育活動等の業務負荷は増加の一途にあります。このような現
私は昨年度から出版委員会に参加させていただいておりますが、初めて参加した編集会議で状ではありますが、研究活動は大学が大学であるための大きな責務であり、外部評価基準の重は、膨大な労力をもって１つ１つの論文が丁寧に審査されていることに大変驚かされました。
要項目であることは言うまでもありません。今後、各講座・部門等でのさらなる研究の発展を委員長を務めさせていただいた本年度は、みなさまの知を結集した本業績集を自信を持って全国に発信できることを誇りに思っています。今後も世界に誇れるような研究成果が信州大学か祈念致します。
ら発信されていくことを祈念しております。
最後に、本業績録の編集にあたりご尽力頂きました先生方、図書館職員の方々に厚く御礼申
最後に、本業績録の編集にあたりご尽力頂きました先生方、図書館職員の方々に厚く御礼申し上げます。
し上げます。



中沢 洋三
浅村英樹

出出 版
版委
委員
員 長：中沢洋三
長：浅村英樹出出 版
委 員：杠 俊介、森 政之、和田有子
版 委 員：奥山隆平、石田文宏、川股知之
医 学 部 図 書 館：岩井雅史、後閑壮登
医学部図書館主査：石坂憲司

信州大学医学部医学科・大学院医学系研究科
・医学部附属病院業績録 第
第 46
38 号
号
平成
平成 23
31 年１月
年 1 月28
31日印刷
日印刷
平成
平成 23
31 年１月
年 1 月28
31日発行
日発行
編集兼 信 州 大 学 医 学 部
発行者 松本市旭 3 丁目 1 の 1
印刷所

藤原印刷株式会社

松本市新橋 7 の 21 番地

ISSN 1881ー4980

信 州 大 学 医 学 部 医 学 科・大 学 院 医 学 系 研 究 科・医 学 部 附 属 病 院 業 績 録

SCIENTIFIC ACHIEVEMENTS OF SHINSHU UNIVERSITY SCHOOL OF
MEDICINE, SHINSHU UNIVERSITY GRADUATE SCHOOL OF MEDICINE,
AND SHINSHU UNIVERSITY HOSPITAL
信州大学医学部医学科・大学院医学系研究科・医学部附属病院業績録

No.46 (2017)

第四六号（二〇一七）
二〇一八

2018