Genetic Background Monitoring Report

No.： 101129-30

BRC No.: RBRC01420
Strain Name (Official Nomenclature): B6;129P2-Irf7<tm1Ttg>
Strain of Origin: Mutant Stock
Strain of origin: 129P2/OlaHsd
Donor strain: E14.1 (ES cell)
Background strain: C57BL/6
Date: 2010/11/29
ID of animals surveyed
S00720102 S00720104(N6F?+F17) (N6F?+F17)(Generation1) / Sex
a-typeb-type (B6 type)
Locus
Type Location2
FemaleMale
1 D1Mit212
SSLP Chr1:40049840-40049985
b/bb/b
C3,FVB
B6,D2,129,BALB,CBA
2 D1Mit306
SSLP Chr1:98827535-98827643
b/bb/b
D2,129
B6,BALB,C3,CBA,FVB
3 D2Mit433
SSLP Chr2:57149522-57149694
b/bb/b
D2,C3,129,CBA,FVB
B6,BALB
4 D3Mit333
SSLP Chr3:44511652-44511774
b/bb/b
C3,CBA,FVB
B6,D2,BALB,129
5 D3Mit106
SSLP Chr3:111841219-111841382
b/bb/b
D2,BALB,C1,129,CBA,FVB
B6
6 D4Mit149
SSLP Chr4:3584271-3584381
b/bb/b
D2,BALB,C3,129,CBA
B6,FVB
7 D4Mit108
SSLP Chr4:38319122-38319254
b/bb/bBALB,C3,129
B6,D2,CBA,FVB
8 D5Mit148
SSLP Chr5:32278263-32278411
b/bb/bBALB,C3,129,CBA,FVB
B6,D2
9 D5Mit168
SSLP Chr5:137534245-137534394
b/bb/b
D2,BALB,C3,129,CBA,FVB
B6
10 D6Mit9
SSLP Chr6:87375892-87376028
b/bb/b
D2,C3,129,CBA,FVB
B6,BALB
11 D7Mit230
SSLP Chr7:56764849-56764953
b/bb/b
D2,C3,129,FVB
B6,BALB,CBA
12 D8Mit293
SSLP Chr8:37226054-37226173b/bb/bD2,BALB,C3,129,CBA,FVB
B6
13 D9Mit191
SSLP Chr9:46494456-46494601
b/bb/b
D2,BALB,C3,CBA,FVB
B6,12914 D10Mit282 SSLP Chr10:20654078-20654202
b/bb/bBALB,129,FVB
B6,D2,C3,CBA
15 D11Mit219 SSLP Chr11:72132472-72132603
b/bb/b
D2,129
B6,BALB,C3,CBA,FVB
16 D12Mit190 SSLP Chr12:60829453-60829579
b/bb/b
D2,FVB
B6,BALB,C3,129,CBA
17 D13Mit179 SSLP Chr13:44860362-44860453
b/bb/bBALB,C3,129,CBA,FVB
B6,D2
18 D14Mit50
SSLP Chr14:21831604-21831793
b/bb/b
D2,BALB,129,CBA,FVB
B6,C3
19 D15Mit138 SSLP Chr15:39861164-39861310
b/bb/b
C3
B6,D2,BALB,129,CBA,FVB
20 D16Mit50
SSLP Chr16:78953071-78953200
b/bb/b
D2,129,CBA,FVB
B6,BALB,C3
21 D17Mit152 SSLP Chr17:65689824-65689949
b/bb/b
D2,BALB,FVB
B6,C3,129,CBA
22 D18Mit68
SSLP Chr18:21594126-21594238
b/bb/b
D2,BALB,CBA,FVB
B6,C3,129
23 D19Mit16
SSLP Chr19:20420342-20420474
b/bb/b
D2,C3,CBA
B6,BALB,FVB
24 DXMit117
SSLP Chr X:127822562-127822687
b/bb/b
D2,129,FVB
B6,BALB,C3,CBA
1
Generation definitions: N_Number of backcross generations; F_Filial or inbreeding generations; M_Cross-intercross breeding generations; ?: Use when theprior breeding history is not known; +_Generation numbers before the "+" took place in the donating investigator, after the "+", at RIKEN BRC.
2
based on UniSTS annotation of NCBI Build 37
Haplotype combination:a/a_a-type homozygous allele, b/b_b-type homozygous allele, a/b_heterozyous allele

Kazuyuki Mekada, Ph.D. (2011/12/8)

Genetic Background Monitoring Report

No.： 100114

BRC No.: RBRC01420
Strain Name (Official Nomenclature): B6;129P2-Irf7<tm1Ttg>
Strain of Origin: Mutant Stock
Strain of origin: 129P2/OlaHsd
Donor strain: E14.1 (ES cell)
Background strain: C57BL/6
Date: 2010/1/14
ID of animals surveyed
S00500201 S00500201(N6F?+F13) (N6F?+F13)(Generation1) / Sexa-typeb-type (B6 type)
LocusType Location2FemaleMale
1 D1Mit212
SSLP Chr1:40049840-40049985
b/bb/b
C3,FVB
B6,D2,129,BALB,CBA
2 D1Mit306
SSLP Chr1:98827535-98827643
b/bb/b
D2,129
B6,BALB,C3,CBA,FVB
3 D2Mit433
SSLP Chr2:57149522-57149694
b/bb/b
D2,C3,129,CBA,FVB
B6,BALB
4 D3Mit333
SSLP Chr3:44511652-44511774
b/bb/b
C3,CBA,FVB
B6,D2,BALB,129
5 D3Mit106
SSLP Chr3:111841219-111841382
b/bb/b
D2,BALB,C1,129,CBA,FVB
B6
6 D4Mit149
SSLP Chr4:3584271-3584381
b/bb/b
D2,BALB,C3,129,CBA
B6,FVB
7 D4Mit108
SSLP Chr4:38319122-38319254
b/bb/bBALB,C3,129
B6,D2,CBA,FVB
8 D5Mit148
SSLP Chr5:32278263-32278411
b/bb/bBALB,C3,129,CBA,FVB
B6,D2
9 D5Mit168
SSLP Chr5:137534245-137534394
b/bb/b
D2,BALB,C3,129,CBA,FVB
B6
10 D6Mit9
SSLP Chr6:87375892-87376028
b/bb/b
D2,C3,129,CBA,FVB
B6,BALB
11 D7Mit230
SSLP Chr7:56764849-56764953
b/bb/b
D2,C3,129,FVB
B6,BALB,CBA
12 D8Mit293
SSLP Chr8:37226054-37226173
b/bb/b
D2,BALB,C3,129,CBA,FVB
B6
13 D9Mit191
SSLP Chr9:46494456-46494601
b/bb/b
D2,BALB,C3,CBA,FVB
B6,12914 D10Mit282 SSLP Chr10:20654078-20654202
b/bb/bBALB,129,FVB
B6,D2,C3,CBA
15 D11Mit219 SSLP Chr11:72132472-72132603
b/bb/b
D2,129
B6,BALB,C3,CBA,FVB
16 D12Mit190 SSLP Chr12:60829453-60829579
b/bb/b
D2,FVB
B6,BALB,C3,129,CBA
17 D13Mit179 SSLP Chr13:44860362-44860453
b/bb/bBALB,C3,129,CBA,FVB
B6,D2
18 D14Mit50
SSLP Chr14:21831604-21831793
b/bb/b
D2,BALB,129,CBA,FVB
B6,C3
19 D15Mit138 SSLP Chr15:39861164-39861310
b/bb/b
C3
B6,D2,BALB,129,CBA,FVB
20 D16Mit50
SSLP Chr16:78953071-78953200
b/bb/b
D2,129,CBA,FVB
B6,BALB,C3
21 D17Mit152 SSLP Chr17:65689824-65689949
b/bb/b
D2,BALB,FVB
B6,C3,129,CBA
22 D18Mit68
SSLP Chr18:21594126-21594238
b/bb/b
D2,BALB,CBA,FVB
B6,C3,129
23 D19Mit16
SSLP Chr19:20420342-20420474
b/bb/b
D2,C3,CBA
B6,BALB,FVB
24 DXMit117
SSLP Chr X:127822562-127822687
b/bb/b
D2,129,FVB
B6,BALB,C3,CBA
1
Generation definitions: N_Number of backcross generations; F_Filial or inbreeding generations; M_Cross-intercross breeding generations; ?: Use when theprior breeding history is not known; +_Generation numbers before the "+" took place in the donating investigator, after the "+", at RIKEN BRC.
2
based on UniSTS annotation of NCBI Build 37
Haplotype combination:a/a_a-type homozygous allele, b/b_b-type homozygous allele, a/b_heterozyous allele

Kazuyuki Mekada, Ph.D. (2011/12/8)

Genetic Background Monitoring Report

No.： -BRC No.: RBRC01420
Strain Name (Official Nomenclature): B6;129P2-Irf7<tm1Ttg>
Strain of Origin: Mutant Stock
Strain of origin: 129P2/OlaHsd
Donor strain: E14.1 (ES cell)
Background strain: C57BL/6
Date: ID of animals surveyedm1
f1
1(N6F?+F1) (N6F?+F1)(Generation ) / SexLocus
Type Location2MaleFemale
SSLP Chr1:19802051-19802209
B6/B6
B6/B6
1 D1Mit3
SSLP Chr1:Syntenic
B6/B6
B6/B6
2 D1Mit322
SSLP Chr1:73734337-73734492
B6/B6
B6/B6
3 D1Mit19
SSLP Chr1:98827535-98827643
129?/129?
B6/B6
4 D1Mit306
SSLP Chr1:154473511-154473632
B6/B6
B6/B6
5 D1Mit501
SSLP Chr1:176558864-176559001
B6/B6
B6/B6
6 D1Mit150
SSLP Chr2:27277814-27277911
B6/B6
B6/B6
7 D2Mit431
SSLP Chr2:65277459-65277647
B6/B6
B6/B6
8 D2Mit9
SSLP Chr2:106750096-106750239
B6/B6
B6/B6
9 D2Mit206
SSLP Chr2:153798642-153798751
B6/B6
B6/B6
10 D2Mit493
SSLP Chr2:168761877-168761999
B6/B6
B6/B6
11 D2Mit456
SSLP Chr2:178535250-178535364
B6/B6
B6/B6
12 D2Mit148
SSLP Chr3:31137265-31137413
B6/B6
B6/B6
13 D3Mit151
SSLP Chr3:71816030-71816141
B6/B6
B6/B6
14 D3Mit278
SSLP Chr3:123334565-123334712
15 D3Mit318
SSLP Chr3:148932688-148932790
B6/B6
B6/B6
16 D3Mit293
SSLP Chr4:3584271-3584381
B6/B6
B6/B6
17 D4Mit149
SSLP Chr4:25610387-25610576
B6/B6
B6/B6
18 D4Mit2
SSLP
Chr4:63026328-63026475
B6/B6
B6/B6
19 D4Mit17
SSLP Chr4:66843059-66843205
B6/B6
B6/B6
20 D4Mit178
SSLP Chr4:123838543-123838630
B6/B6
B6/B6
21 D4Mit308
SSLP Chr4:153093974-153094108
129?/129?
B6/B6
22 D4Mit254
SSLP Chr5:8797672-8797875
129/129
23 D5Mit48
SSLP Chr5:Syntenic
129/129
B6/12924 D5Mit267
SSLP Chr5:89700063-89700172
129/129
25 D5Mit398
SSLP Chr5:125309605-125309718
B6/B6
B6/B6
26 D5Mit95
SSLP Chr5:127286127-127286250
B6/B6
B6/B6
27 D5Mit320
SSLP Chr5:139608988-139609104
B6/B6
B6/B6
28 D5Mit374
SSLP Chr6:55505943-55506037
B6/B6
B6/B6
29 D6Mit316
SSLP Chr6:87375892-87376028
B6/B6
B6/B6
30 D6Mit9SSLP Chr6:93413943-93414087
B6/B6
B6/B6
31 D6Mit102
SSLP Chr6:114232092-114232201
B6/B6
B6/B6
32 D6Mit55
SSLP Chr6:136372097-136372213
B6/129B6/12933 D6Mit339
SSLP Chr7:31118079-31118215
B6/B6
B6/B6
34 D7Mit246
SSLP Chr7:52767912-52768056
B6/B6
B6/B6
35 D7Mit81
SSLP Chr7:126237672-126237821
B6/B6
B6/B6
36 D7Mit238
SSLP Chr7:Syntenic
129/129
129/129
37 D7Mit189
Kazuyuki Mekada, Ph.D. (2011/12/8)

Genetic Background Monitoring Report

No.： -BRC No.: RBRC01420
Strain Name (Official Nomenclature): B6;129P2-Irf7<tm1Ttg>
Strain of Origin: Mutant Stock
Strain of origin: 129P2/OlaHsd
Donor strain: E14.1 (ES cell)
Background strain: C57BL/6
Date: ID of animals surveyedm1
f1
1(N6F?+F1) (N6F?+F1)(Generation ) / SexLocus
Type Location2
MaleFemale
SSLP Chr8:37226054-37226173
B6/B6
B6/B6
38 D8Mit293
SSLP Chr8:91727514-91727649
B6/B6
B6/B6
39 D8Mit81
SSLP Chr8:Syntenic
B6/B6B6/B6
40 D8Mit14
SSLP Chr9:41695932-41696113
B6/B6
B6/B6
41 D9Mit328
SSLP Chr9:87838840-87839011
B6/B6
B6/B6
42 D9Mit269
SSLP
Chr9:115307830-115307967
B6/B6
B6/B6
43 D9Mit214
B6/B6
B6/B6
44 D10Mit282 SSLP Chr10:20654078-20654202
B6/B6
B6/B6
45 D10Mit223 SSLP Chr10:67674940-67675089
SSLP Chr10:91885360-91885556
B6/B6
B6/B6
46 D10Mit11
B6/B6
B6/B6
47 D10Mit180 SSLP Chr10:117587667-117587800
48 D11Mit236 SSLP Chr11:45088548-45088651
49 D11Mit260 SSLP Chr11:61609496-61609590
B6/B6
B6/B6
50 D11Mit219 SSLP Chr11:72132472-72132603
B6/B6
B6/B6
51 D11Mit333 SSLP Chr11:108575096-108575220
B6/B6
B6/B6
52 D12Mit153 SSLP Chr12:35920169-35920310
SSLP Chr12:70900839-70901009
B6/B6
B6/B6
53 D12Mit34
B6/B6
B6/B6
54 D12Mit102 SSLP Chr12:105536654-105536786
SSLP Chr12:Syntenic
B6/B6
B6/B6
55 D12Mit7
56 D13Mit117 SSLP Chr13:37654832-37654949
B6/B6
B6/B6
57 D13Mit179 SSLP Chr13:44860362-44860453
B6/B6
B6/B6
58 D13Mit147 SSLP Chr13:98359080-98359187
SSLP Chr13:120128451-120128643
B6/B6
B6/B6
59 D13Mit35
B6/B6
B6/B6
60 D14Mit259 SSLP Chr14:54729500-54729624
B6/B6
B6/B6
61 D14Mit193 SSLP Chr14:71921427-71921544
B6/B6
B6/B6
62 D14Mit165 SSLP Chr14:106982674-106982807
B6/B6
B6/B663 D15Mit136 SSLP Chr15:30776615-30776757
SSLP Chr15:43279930-43280030B6/B6
B6/B6
64 D15Mit5
SSLP Chr15:74075586-74075734
B6/B6
B6/B6
65 D15Mit29
SSLP Chr15:83586169-83586316
B6/B6
B6/B6
66 D15Mit33
B6/B6
B6/B6
67 D16Mit131 SSLP Chr16:7319135-7319274
SSLP Chr16:38433970-38434154
B6/B6
B6/B6
68 D16Mit59
SSLP Chr16:78953071-78953200
B6/B6
B6/B6
69 D16Mit50
B6/B6
B6/B6
70 D16Mit106 SSLP Chr16:98051757-98051902
B6/B6
B6/B6
71 D17Mit213 SSLP Chr17:16752157-16752280
B6/B6B6/B6
72 D17Mit108 SSLP Chr17:49744546-49744658
B6/B6
B6/B6
73 D17Mit187 SSLP Chr17:79631462-79631708
B6/B6
B6/B6
74 D18Mit177 SSLP Chr18:41142161-41142331
Kazuyuki Mekada, Ph.D. (2011/12/8)

Genetic Background Monitoring Report

No.： -BRC No.: RBRC01420
Strain Name (Official Nomenclature): B6;129P2-Irf7<tm1Ttg>
Strain of Origin: Mutant Stock
Strain of origin: 129P2/OlaHsd
Donor strain: E14.1 (ES cell)
Background strain: C57BL/6
Date: ID of animals surveyedm1f11(N6F?+F1) (N6F?+F1)(Generation ) / SexLocus
Type Location2MaleFemale
B6/B6
B6/B6
75 D18Mit184 SSLP Chr18:66978897-66979068
B6/B6
B6/B6
76 D18Mit142 SSLP Chr18:75548607-75548726
B6/B6
B6/B6
77 D18Mit216 SSLP Chr18:83585146-83585269
SSLP Chr19:21916083-21916201
B6/B6
B6/B6
78 D19Mit96
SSLP Chr19:37331405-37331552
B6/B6
B6/B6
79 D19Mit88
D19Mit90
SSLP
Chr19:42295742-42295862
B6/B6
B6/B680
SSLP Chr19:59674330-59674465
B6/B6
B6/B6
81 D19Mit71
B6/B6
B6/B6
82 DXMit166 SSLP ChrX:49036675-49036788
B6/B6
B6/B6
83 DXMit210 SSLP ChrX:69741824-69741934
84 DXMit130 SSLP ChrX:130298712-130298880
1
Generation definitions: N_Number of backcross generations; F_Filial or inbreeding generations;
M_Cross-intercross breeding generations; ?: Use when the prior breeding history is not known;+_Generation numbers before the "+" took place in the donating investigator, after the "+", at RIKEN BRC.
2based on UniSTS annotation of NCBI Build 37
Haplotype combination:
B6/B6_C57BL/6 homozygous allele, 129/129_129 homozygous allele, B6/129_heterozyous allele

Kazuyuki Mekada, Ph.D. (2011/12/8)