Department Winter Seminar Program＊１人 20 分前後：15 分発表、5 分討論を目安として下さい。
＊パワーポイントスライドは英語でお願い致します。発表は日本語、英語、自由です。

＊ 第１日目 12 月 15 日（月） Dec 15, Mon

10：30 ~ 17：10

Ⅰ Basic principles of tumor immunity I 【 10：30~11：50  Chairperson／T. Tsukahara 塚原 智英 】
1.

New antibodies directed to tumor-associated HLA/peptide complex
T. Tsukahara 塚原 智英

2.

T cell immunomonitoring and TCR cloning in patients immunized with HLA-A24 survivin-2B/PBFpeptides.                          K. Watanabe 渡邉 一絵

3.


Identification of a novel human T cell population with the characteristics of stem cell memory
K. Murata 村田 憲治

4.

Establishment of the artificial CTL clone expressing TCR highly reacting with autologous SP ells
towards identification of a sarcoma stem cell antigen.
Y. Shibayama 芝山 雄二

Lunch Time 【 11：50~13：00 】

Ⅱ

Basic principles of tumor immunity Ⅱ【 13：00~14：00  Chairperson／T. Kanaseki 金関 貴幸 】

5.

Natural peptides and cancer immunotherapy
T. Kanaseki / D. Morooka 金関 貴幸 / 諸岡 大地
V. Kochin コーチン・ビタリー

6.

HLA-A24 peptidomics of cancer and cancer stem cells

7.

CTL responses to the natural ASB4 peptide presented by cancer stem cells
S. Miyamoto 宮本 昇Coffee Break 【 14：00~14：10 】

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Ⅲ

Basic principles of tumor immunity Ⅲ【 14：10~15：10  Chairperson／V. Kochin ビタリー・コーチン 】

8.

A novel strategy to cope with tapasin-deficiet variants of cancers
Y. Shionoya 塩野谷 洋輔

9.

Finding natural peptides presented by HLA-A2 of cancer stem cells
S. Hamada 濱田 早紀

10. MHC class I antigen processing of cancer stem cellsM. Ueki 植木 美渚

Coffee Break 【 15：10~15：20 】

Ⅳ Molecular nature of stress responses I【 15：20~16：20  Chairperson／T. Suzuki 鈴木 健史 】
11. Unexpected link of cancer-associated ERO1-! and Yamanaka factor KLF-4 in cancer stem-like cellT. Tanaka 田中 努
12. Elucidation of hypoxia-inducible transcriptional factor of ERO1-!    T. Kajiwara 梶原 敏充
13. An exploration of priming factor from patient plasma in NHTR (Non-hemolytic transfusion reactions)D. Takahashi 高橋 大輔

 Coffee Break 【 16：20~16：30 】

Ⅴ Progress and perspective in clinical study【 16：30~17：10  Chairperson／G. Kutomi 九冨 五郎 】
14. An interim report of SUCCESS: Phase II study for inoperable pancreatic cancer patients.
H. Shima 島 宏彰
15. Next stage of Department of Surgery, Surgical Oncology and Science
G. Kutomi 九冨 五郎
-2-＊ 第２日目 12 月 16 日（火）Dec 16, Tue

9：40 ~ 17：25

  Ⅵ Post - modern aspect of biological research【 9：40~10：20 Chairperson／Y. Hirohashi 廣橋 良彦 】
16. New Molecular Pathology（Integrated single cell transcriptome）  S. Hashimoto 橋本 真一（Kanazawa University）

17. Live cell imaging of the ASB4-specific CTL
T. Suzuki / C. Nakayama 鈴木 健史 / 中山 智絵
Coffee Break 【 10：20~10：30 】
Ⅶ Basic principles of tumor immunity Ⅳ【 10：30~11：50  Chairperson／R. Morita 守田 玲菜 】
18. The immunological aspects of cancer stem-like cells.         Y. Hirohashi 廣橋 良彦
19. Novel markers for colon cancer stem cells.              E. Morita 守田 玲菜

20. Glycosialylation may play a important role in maintaining stemness in colorectal cancer.
T. Ogawa 小川 宰司
21. Immune system-related molecule expression in cancer stem cells    

H. Maruyama 丸山 創

Lunch Time 【 11：50~13：00 】

Ⅷ Basics of bioscience     【 13：00~14：00 Chairperson／L. Li 李 黎明 】
22. Leptin inhibits Human lymphatic endothelial cells to tube formation by inhibiting the expression ofIL-6 receptor.                           A. Sato 佐藤 明紀
23. Fluorescence laparoscopy imaging of sentinel lymph node metastasis in vivo mouse model
T. Saito / L. Li齋藤 琢麿/李 黎明

（Chitose Institute of Science and Technology）-3-

24. The introduction of an improved method on the measurement of total collagen content in cultured cells
N. Takahashi 高橋 延昭
Coffee Break 【 14：00~14：10 】
Ⅸ Molecular nature of stress response and tumor immunity Ⅱ       【 14：10~15：30  Chairperson／S. Hashimoto 橋本 真一 】
25. Immunological Aspects of Colorectal Cancer Stem Cells        

L. Wang 王 利明

26. Lung cancer stem-like cells are generated by epigenetic regulation attributing to oxidative stress
H. Saijo 西條 浩
27. Trial of the genome editing using the CRISPR/cas9 system for research on tumor maintenance ofSOX2 gene                           R. Horibe 堀部 亮多
28. Analysis of CSC related gene Dnajb8 using the knockout system of CRISPR/Cas9M. Yamashita 山下 真路

Coffee Break 【 15：30~15：45 】

Ⅹ Basic principles of tumor immunity Ⅴ       【 15：45~17：05  Chairperson／S. Takahashi 高橋 秀史 】
29. Arrythmogenic right ventricular cadiomyopathy and sudden cardiac death
S. Takahasshi 高橋 秀史
30. BORIS variant subfamily 6 is involved in gynecological cancer stemness and can be a immunologicaltherapeutic target.                        T. Asano 浅野 拓也 
31. Enigmatic mechanisms of keeping stemness in ovarian CSCs, depending on MMP10
T. Mariya 真里谷 奨
32. Immunopathological properties of cancer stem cells: CST antigens and immune checkpoint ligands
T. Torigoe / H. Asanuma 鳥越 俊彦/浅沼 広子

XI Closing remark       【 17：05~17：25 】
33. The final message to the Department      -4-

N. Sato 佐藤 昇志