Module Code20349014

Course Term

Course Subject Name

Introductory Biochemistry

SpringCourse Tutor

Yasuaki Hiromasa

The 4th Semester

Credit2Schools

School of Agriculture

Taught YearThe 2nd yearCampus

Ito campus

Subject Area
Course Subject Classification
Course Requirements
Course Requirement(Pre-requisite)

LectureCommon Basic Subjects

Taught Day

MON-3
Monday, 3rd period (13:00-14:30)

Class attendance, quiz and exams. Students who fail to attend 3 or more lectures may be recognized “DROPPED” from thecourse. The course will not be dropped if a valid excuse is given.
Taking Introductory Biology (I, II: 1304) & Fundamental Cell Biology (I, II: 1408) course subjects are recommended.

Course Outline
The course involves the study of the molecular composition of living cells. ZThe biological macromolecules which this course focuses on are nucleotides
including DNA/RNA, nucleic acids, amino acids, proteins, carbohydrate, and lipid. Also Higher structure of nucleic acids and proteins are also examined.
Methods and approaches used in biochemical research will be presented as will the biochemical basis of some diseases.

key words
Biological macromolecule, nucleic acid, nucleotide, amino acid, peptide, protein, carbohydrate, lipid, lipid bilayer, membrane protein.
Study Objectives (General)
The overall goal is for the student to understand fundamental principle of biochemical concepts. Upon completion of the course, the student should achieve
Study Objectives (Specific)

The course aims to achieve the following:

Knowledge & understanding: understand the structure and function of biomolecules.
Scientific thinking: By having fundamental concepts of biomolecules, biochemical phenomena will be understood logically and scientifically. Intentionality andscientific communication: acquisition of positive learning by presentation opportunity.
Course PlanStudents should look at the moodle site at this class for e-learning.
1. Introduction of the class and small test. DNA Structure, Function, and Engineering (1): Nucleic acid structure and function.
2. DNA Structure, Function, and Engineering (2): Nucleic acid sequencing; Manipulating DNA.
3. Amino Acids: Amino acid structure, stereochemistry, amino acid derivatives.
4. Proteins: Primary structure (1): Polypeptide diversity; Protein purification and analysis.
5. Proteins: Primary structure (2): Polypeptide sequencing; Protein evolution.
6. Protein Structure and Folding (1): Secondary and tertiary structures.
7. Protein Structure and Folding (2): Quaternary structure and symmetry, protein folding.
Presentation of the topics relating with the subjects.
8. Physiological activities of protein(1). Oxygen Binding to Myoglobin and Hemoglobin
9. Physiological activities of protein(2). Muscle Contraction & other proteins
10. Saccharide Chemistry (1): Monosaccharides Polysaccharides & Glycoproteins
11. Saccharide Chemistry (2) & presentations of the topics(protein function & saccharides).
12. Lipids, Bilayer, and Membranes: Lipid Classifi cation, Lipid Bilayers.Membrane Proteins, Membrane Structure and Assembly
13. Passive and Active Transport (1)Passive-Mediated Transport, Thermodynamics of Transport
14. Passive and Active Transport (2)Active Transport & presentations
Course Approaches

Lecture is based on e-learning (2020) Using powerpoint slides, homework and presentation.

Textbooks

Principles of Biochemistry, 4th edition by Voet, Voet & Pratt (Willey Inc) ISBN 978-1-118-09244-6

Reference Books

Sadava, Hillis, Heller, Berenbaum (2012) Life;The Science of Biology

Study consultation

I prefer that you can schedule an appointment by email.

(office hour)

Office: W475, Office hours : by appointment, email: hiromaassr@agr.kyushu-u.ac.jp
Evaluation of 2020 class will be anounced at the 1st class(e class)Following is for regular lecture style class.
Grades will be based on the following items:• Attendance 20%• Class activities (homework, presentation) 20%• Final exam 60%

Exams/Results

Grade A: >90-100, B: 89-80, C: 79-70, D: 69-60, F: <60

Evaluation Method** Rubric of Final exam:
A: Required categories of molecules are fully understood and their knowledge can be applied to understand biochemical
reactions and phenomena.
B : Understanding of the required categories of sugar section is satisfactory.
C : Basic principles of biomolecules and their basic function are comprehended.
D : Basic principles of structure and function of biomolecules can be described/understood.
E : Understanding the basis of structure and function of the biomolecules arenʼt satisfactory.

Others