Jpn J Extra-Corporeal Technology 45（1）：1 − 7, 2018

Study profile of the perfusion registry in Japan
Makoto Hibiya 1），Tetsuya Kamei 1），Shoji Kubota 2），Kyoichi Kemmoku 3）
Koji Takai 4），Chihiro Saito 5），Atsushi Sekiguchi 6），Shigeru Minami 7）
Hiroki Hayashi 8），Kiyoshi Yoshida 9），Noboru Motomura 10）
Abstract
In response to activities of the International Consortium for Evidence-Based Perfusion, the Japanese Society ofExtra-Corporeal Technology in Medicine started planning the preparation of scientific evidence-based guidelines
for extracorporeal circulation in Japan in 2008, and after an about 6-year preparation period, registration of extracorporeal circulation cases was initiated in 2014. This project consists of cooperation between ‘case registration’ by
participant institutions in which each case is input following the definitions of registration items without error and‘case database’ in which registered cases are collected, managed, tabulated, and analyzed. The numbers of participant institutions and registered cases including those which participated in an open input test performed in 2013reached 30 institutions and 7,443 cases by the end of 2016. Institutions participating in this project account for all
Japan Adult Cardiovascular Surgery Database ( JACVSD) -participant institutions. When registration of pediatriccases of extracorporeal circulation starts, a cohort study using the extracorporeal circulation case database will
progress, and its achievement, scientific evidence, may lead to stability and improvement of clinical extracorporeal
circulation techniques and development of the guidelines.
Key words：cardiopulmonary bypass，database, case registry，extra-corporeal circulation

Ⅰ．Introduction

Oceanian, and Asian academic societies on extracor-

The American Society of Extra-Corporeal Technol-

poreal circulation. The objective of ICEBP is to formogy (AmSECT) organized the International Consor-

several activity organizations, prepare scientific evi-tium for Evidence-Based Perfusion ( ICEBP) based ondence-based guidelines for the extracorporeal circula-scientific evidence as a new committee organization

tion field, and provide these to clinical techniques. 1)

in 2006. The Japanese Society of Extra-Corporeal

Executive members of ICEBP published review

Technology in Medicine ( JaSECT) participated inarticles based on the classification and evidence levelits management organization with several European,in the American Heart Association and the American

The Japanese Society of Extra-Corporeal Technology in Medicine

Corresponding Author：Makoto Hibiya

1）School of Health Sciences, Fujita Health University

Faculty of Clinical Engineering, School of2）Asahikawa City Hospital

Health Sciences, Fujita Health University3）Saitama Medical University

1-98, Dengakugakubo, Kutsukake-cho,4）National Hospital Organization Nagoya Medical Center

Toyoake, Aichi, 470-1192, Japan5）Graduate School of Medicine, Fujita Health University6）Saitama Medical University International Medical Center［Received December 22, 2017：Accepted January 25, 2018］

7）Kobe University Hospital8）Tokai Memorial Hospital9）Osaka University Hospital
10）‌Faculty of Medicine, Sakura Medical Center, Toho University

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College of the Cardiology Task Force on Practicesuch as asking institutions for participation, setting

Guidelines in the same and following years.

These

a desk for inquiries related to the project for partici-

activities were great opportunities leading to seekpant institutions and patients, procedures of participa-

for an academic basis of extracorporeal circulation intion in the case registration for institutions and datacase registration epidemiological studies in Japan. To

manager registration, management of the extracorpo-

prepare scientific evidence-based guidelines for ex-

real circulation case database, data manager meeting,tracorporeal circulation in Japan in response to thetabulation and analysis of all registered case data and

ICEBP activities, JaSECT started planning in 2008.

case data within participant institutions, feedback ofThey visited America and Australia to investigate

the tabulation and analysis results to participant in-

the state of activities,

stitutions, and re-examination of the case registration

4)

2, 3 )and surveyed basic informa-tion concerning execution of extracorporeal circula-items and definitions.

tion in institutions in 2011 aiming at constructing anwith the state of input items for registration of adult

Ⅱ．Overview of extracorporeal circulationcase registration

cases of extracorporeal circulation. 5) The results of

1．Objective

extracorporeal circulation case database matchedthis survey met the data collection items concerning

The objectives are progression of extracorpo-

operation of extracorporeal circulation recommended

real circulation techniques in Japan and contribu-

by ICEBP. Based on these results, we combined items

tion to promotion of national medical care andconcerning extracorporeal circulation during open

health through surveying the preoperative medical

heart surgery and related minimum required patientphysical state of patients undergoing cardiovascular

information items as draft case registration items.

surgery or treatment under extracorporeal circula-

In 2012, the database input form and input

tion, execution status, and results of extracorporeal

procedure were prepared using these draft case reg-

circulation, preparation of database of these and na-

istration items, and then an input test and hearing

tionwide summation, tabulation and analysis of large-

survey on the input operation state were performed.

scale samples using these data, and provision of theBased on the hearing survey, specific descriptions inresults of these. In addition, enabling risk assessment

the input procedure were added and correction ofof extracorporeal circulation by international collabo-

input form failures were performed.

ration is aimed at.

6)

In 2013, institutions participating in the registra-

2．Subjects

tion of extracorporeal circulation cases were publi-

The target of collection is only adult patientscally recruited and an input test was performed. The

aged 16 years or older, and each case of open heart

items with incorrect input and data missing were

surgery accompanied by extracorporeal circulation isdifferent among the institutions, and the same in-regarded as one registration.

stitutions repeated in the same item. Therefore, theFor institutions to participate in this case registra-

input procedure was revised and called to attention.

tion, approval by each institutional review board or

A meeting of data entry workers of the participant in-director of the institution is required. In addition, thestitutions was held and the situation was explained. 7 )data manager managing case registration at each in-

After an about 6-year preparation period as

stitution is required to be a full member of JaSECT.

described above, registration of extracorporeal circu-

3．Methods

lation cases was initiated with JaSECT as the parent

For the registration of extracorporeal circulation

organization of the project in 2014. This projectcases, FileMaker Pro ® ( FileMaker Inc.) was used.

consists of cooperation between ‘case registration’ byThis software can be used on the major OS, Windows

participant institutions in which each case is input

and Mac OS, and inputters can use any personal

following the definitions of registration items without

computer. For the collector side, this software has

error, and ‘case database’ in which registered cases

high affinity to spreadsheet and statistical analysis

are collected, managed, tabulated, and analyzed, forsoftware, being advantageous.

which JaSECT performs diverse activities to register

Data accumulated at each institution are output

all cases of extracorporeal circulation nationwide,

as a spreadsheet software file and collected through2

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Jpn J Extra-Corporeal Technology 45（1），2018

the internet using the Web mail system exclusivewith AmSECT. The items and definitions were trans-

for JaSECT members. In this system, inter-terminal

lated into Japanese and matched.

communication is sent and received using the SSL

5．State of registration
The numbers of participant institutions and reg-encryption communication and security against data

istered cases including those in the open input test

exploitation during communication is ensured.
Data accumulated at each institution is collected

performed in 2013 are increasing yearly. Sixteen in-

at Fujita Health University, compiled to a database,stitutions participated in 2013, and several institutions

and tabulated and analyzed using JMP ® (SAS Corp.).

participated yearly thereafter, reaching 30 institutions

The tabulated results are published at data manager

by the end of 2016. During this period, the number

meetings (twice/year). In these meetings, aggregat-of cases registered from the participant institutions

ed results based on all data are reported, and datareached 7,443 ( Table 1).

managers receive aggregated results of their own

On summation by the main target disease of

institution and overall aggregated results throughsurgery, surgery for valvular disease alone (43.4％)

electronic media ( JaSECT ethical review approvalis the most frequently performed, followed by aortic

001, Fujita Health University ethical review approval

surgery (24.8％). The combined rate of surgery for

HM17-088).

coronary artery bypass alone (11.2％) and combined

4．Contents of registration items

surgery with that for valvular disease was 22.9％( Table 2).

This case registration is comprised of 6 fields: basic
patient information, circuit and filling fluid, extracor-

Ⅲ．Discussion

poreal circulation, in-and-out management, test data
management, and outcome management, contain-

In 2014, 540 institutions performed cardiovascular

ing 84 multiple-choice input items and 159 descrip-

surgery in Japan, and the number of cases was 66,453

tive items (inputting numerical values), 243 items in(including pediatric cases). 8) On the assumption that

total. Of these, 46 multiple-choice input items and 131

the same number of institutions performed surgery at

descriptive items (inputting numerical values) are

the end of 2016, the rate of institutions participating

essential, 177 items in total (Fig.1-1, 1-2). The input

in the registration of extracorporeal circulation is 5.6

items are mostly the same as those in the registra-％, and the rate of the registered cases is 4.8％. Ontion of extracorporeal circulation cases, PERForm,the other hand, according to the Japan Cardiovascu-

performed in State of Michigan, US, in collaboration

lar Surgery Database Organization ( JCVSDO) collect-

Table 1

ing adult cases, 63,168 cases were collected from 573‌Participated institutions and harvested cases between 2013 and 2016

institutions in 2016, 9) and the rates of institutions participating in the registration of extracorporeal circula-calendar year

number of participating
institutions

number of cases

tion and registered cases were 5.2 and 5.0％, respec-

2013

16

  486

tively. The numbers were small in both databases, but

2014

19

1,587

it may be possible to report the state and outcome

2015

27

2,213

of extracorporeal circulation by analyzing the data

2016

30

3,157

registered in the extracorporeal circulation case

total

7,443
Table 2

databases. The mean number of case registrations

Number of CPB cases categorized with type of procedures
type of procedure

calendar year

isolated
CABG

isolated
valve

CABG andvalve

CABG and
other

aorta

congenital

other

NA

2013

46

  209

55

   8

  134

   7

27

0

2014

161

  743

155

21

  370

19

118

0

2015

282

  965

226

35

  516

43

146

0

2016

347

1,312

304

69

  825

68

230

2

Total

836

3,229

740

133

1,845

137

521

2

NA：not abailable

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National Perfusion Registry
A. Demographic and Case DetailCenter ID

Located country

Perfusion Record No.
Number of perfusion (Admission date was same)□1:1st, □2: 2nd, □3: 3rd, □4: 4th, □5: 5th or grater
First perfusion record No.(Admission date was same)
Gender □1:M, □2:F

Surgery date
(Y/M)
Age at surgery
years
monthsAdmission to surgery
days, Hospital stay
days,
Surgery to discharge
days
Status □1:Elective,□2:Urgent,□3:Emargent,□4:Salvage
Discharge Location □1:Home, □2:Other Hospital, □3:Dead,□4:Other (Unknown)
Surgical Information
Type of Surgery □1:CABG, □2:Valve, □3:CABG+Valve,□4:CABG+other, □5:Aorta,□6:Congenital(Adult), □7:Other
Number of CABG anastomosis sites
Aortic Valve Procedure □1:No, □2:Repair etc, □3:Replacement
Mitral Valve Procedure □1:No, □2:Repair etc, □3:Replacement
Tricuspid Valve Procedure □1:No, □2:Repair etc,
□3:Replacement
Pulmonary Valve Procedure □1:No, □2:Repair etc,
□3:Replacement
Aorta Procedure □1:No, □2:Repair etc, □3:Replacement
Others □1:No,□2:LV procedure or LV rupture repair, □3:VSD,□4:ASD, □5:Arrhythmia correction surgery,□6:Carotid
endarterectomy, □7:Peripheral
Vascular,□8:Thoracic,□7:OtherCV Surgical History
CV surgery history □1:1st ope, □2:re-ope(1st), □3:re-ope(2nd),□4:re-ope(3rd), □5:re-ope(4th or grater)
Previous CV surgery type □1:No, □2:CABG, □3:Valve,□4:Aorta, □5:Congenital, □6:Other cardiac
Pre-Operative Physical Information
MI history □1:No, □2:Less than 6hrs, □3: 6 to 24hrs, □4: 1 to
7days, □5: 8 to 21days, □6: Grater than 21days
LV Fraction □1:good, □2:medium, □3:bad
LVEF method □1:LV gram, □2:Echo, □3:Radio nucleotide,□4:Estimate, □5:Others
Cardiac Output(pre-induction)
L/min.
Risk Factors
CHF□1:No, □2:Yes, □3:Unknown
Chronic Lung Disease □1:No, □2:Yes, □3:Unknown
Smoking□1:No, □2:Yes, □3:Unknown
Diabetes□1:No, □2:Yes, □3:Unknown
Arrhythmia□1:No, □2:Yes, □3:Unknown
Hypertension□1:No, □2:Yes, □3:Unknown
Hyperlipidemia□1:No, □2:Yes, □3:Unknown
Non cardiac vascular disease □1:No, □2:Yes, □3:Unknown
Cerebral vascular disease□1:No, □2:Yes, □3:Unknown
Renal Failure□1:No, □2:Yes, □3:Unknown
Dialysis□1:No, □2:Yes, □3:Unknown
Height
BMI
Perfusionist
Surgeon:cm, Weight
BSA
Main:

m2

kg, Creatinine

mg/dL

Sub:

Note
Name in initial (Last)

B i r t h
Admission
Surgery
Discharge

B. Circuit
Arterial ﬁlter mesh sizeµｍ
Pre-bypass ﬁlter □1:No, □2:Yes
pH management □1:No, □2:α Stat, □3:pH Stat, □4:BothBiopassive coating area □1:None, □2:Limited component,□3:All but cannulae, □4: Tip to tip
Biopassive coating type
□1:X coating(Terumo), □2:SMARTx(Cobe), □3:Physio(Sorin),□4:Carmeda(Medtronic), □5:Trillium(Medtronic),□6:GBS(Gish), □7:Bioline(Jostra), □8:Safeline(Maquet),□9:Duraﬂow(Baxter), □10:COAFREE(JMS),□11:Heparin(MERA), □12:Other
Venous reservoir type □1:Opened, □2:Closed, □3:Not use
Venous reservoir ﬁlter mesh sizeµｍ
Arterial pump head
□1:Roller pump, □2:Rotaﬂow(Jostra),□3:Biomedicus(Medtronic), □4:Revolusion(sorin),□5:Sarns(Terumo), □6:Capiox (terumo),□7:Duraﬂo,HPM(MERA), □8:Turbo(JMS)
Venous return□1:Gravity, □2:Vacuum assist, □3:Pump assist
Pump mode □1:Steady, □2:Pulsatile
Selective perfusion □1:No, □2:Yes

Priming volumes and Blood products

Static circuit vol.
mL
Blood vol.
mL
Total priming vol.
mL
Main priming solution□1:0.9% Saline, □2:Lactated Ringer, □3:Acetate Ringer,□4:Bicarbonate Ringer, □5:Hartmanns, □6:Normosol,□7:Starch or dextran, □8:Other(Crystalloid only)
Autologous Circuit Prime□1:No, □2:Retrograde autologous prime,□3:Banked autologous blood used
Leukodepletion □1: No, □2:Radiation, □3:Filter

C. Perfusion time

Pump timemin.
Clamp timemin.
Re-perfusion time □1:No, □2:Yes
min.
□1:Hemodynamic instability, □2:Pulmonary failure, □3:Regrafting, □4:Bleeding, □5: Valve function failure,□6:Other
Whole perfusion arrest(Y/M/D)(Y/M/D)

Bladder(Y/M/D)(Y/M/D)

HighestLowestJugularHighestNasophaEsophaRectalTympanic

Highest blood temp℃（Arterial ﬂow）

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min.

Clamp □1:No, □2:Yes, 3:Balloon Occlusion
Arrest type □1:No, □2:Cardioplegia, □3:V-Fib, □4:Beating
Type of CPS □1:None, □2: 1:1, □3: 2:1, □4: 3:1, □5: 4:1,
□6: 5:1, □7: 6:1, □8:7:1, □9: 8:1, □10: 9:1,
□11: 10:1, □12:Crystalloid, □13:Comb,□14:Mycroplegia
Cardioplegia Regime□1:First infusion only, □2:Intermittent, □3:Continuous□4:Combine, □5: Intermittent with Continuous Blood
Induction Details
Temp □1:Cold (<28℃), □2:Tepid (28 - 34℃), □3:Warm (>34℃)
Route □1:Antegrade, □2:Retrograde, □3:Both
Maintenance Details
Temp □1:Cold (<28℃), □2:Tepid (28 - 34℃), □3:Warm (>34℃)
Route □1:Antegrade, □2:Retrograde, □3:BothLongest cardioplegia interval
min.
Filter □1:No, □2:Yesµm
Hot Shot used □1:No, □2:Yes℃
Sum of cardioplegia solution
mL (Exclude blood)

Temperature(℃)(First)□1:No, □2:Yes

Cardioplegia

Parameter of the Perfusion Registry（1）

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National Perfusion Registry
Selective Cerebral Perfusion □1:No, □2:Yes

No. of pumps for SCP□1:Only branch of Arterial line, □2:1 roller pump,□3: 2 roller pumps, □4: 3 roller pumps, □5:Centrifugal pump
Antegrade SCP cannulation□1:No, □2:Brachiocephalic A, □3:R-axillary A, □4:L-common
carotid A, □5:L-subclavian A, □6: L-axillary A
Retrograde SCP □1:No, □2:Yes
Independed heat exchanger used for SCP □1:No, □2:Yes
Cerebral perfusion time
Antegrademin.
Retrogrademin.
Cerebral circulatory arrest timemin.
Separated systemic circulatory arrest time
Separated systemic circulation □1:No, □2:Yes

min.

min.

Cannulation
Arterial □1:Aorta, □2:Femoral, □3:Axillary, □4:Other
Cannulation changed □1:No, □2:Addition □3:Yes
Venous □1:Right atrium, □2: SVC + IVC, □3:Femoral,□4:Jugular, □5:SVC, □6:,IVC □7:Other
Anticoagulation
ACT □1:Post Intubation
sec., □2:Post systemic
heparinization
sec., □3:Highest on CPB
sec., □4:Lowest on CPB
sec., □5:Post Protamine
infusionsec.
Whole circuit replacement□1:No, □2:Addition or replace limited parts □3:Yes
D. Fluid volume management（In）
Priming
IntraOp
IntraOp(CPB) (No-Prime・No-CPB)
RBC(Non-Leukoreduced)
RBC(Leukoreduced)

(U)
(U)

Platelets
Cell Saver

(U)
(mL)

Other Blood product20% Albumin
Starch or dextran
RBC was washed with Cell Saver prior to administration.
□1:No, □2:Portion, □3:Yes

(mL)
(mL)
(mL)

FFP
5% Albumin
25% Albumin

(U)
(mL)
(mL)

Conc. Circuit Blood
Harvested Circuit Blood
Whole Blood

E. Lab data

Post
Intubation

First on CPB

Highest on
CPB

Lowest on
CPB

(mL)
(mL)
(mL)

Last on CPB

Total volume
Crystalloid
mL Colloid
mL
Maximum administered solution□1:0.9% Saline, □2:Lactated Ringer, □3:Acetate Ringer,□4:Bicarbonate Ringer, □5:Hartmanns, □6:Normosol,□7:Starch or dextran, □8:Other(Crystalloid only),□9:Unknown
Other total vol.
mL (medicine, cardioplegia, etc)
Medications(IntraOp)
Heparin(Units)Total dose
Antiﬁbrinolytic□1:No, □2:e-Aminocaproic acid, □3:Tranexamic Acid
Renal Management□1:No, □2:Furosemide, □3:Mannitol, □4:Fanoldapam,□5:Vasopressin
Fluid volume management（Out）
Autologous Blood Harvest □1:No, □2:YesmL
Circuit Blood Harvest□1:No □2:YesmL,
Unprocessed cardiotomy suction returned to bypass circuit.
□1:No, □2:Yes
Filtration □1: No, □2: MUF, □3: HF, □4: HD, □5: Other
Added solution volume for MUF
mLUrine
Ultraﬁltration
Wasted Blood

CPB

mL
mL
mL

E. Lab data

Post CPBmL
mL
mL
Next Sheet̶̶>F. Outcomes

Complications
Af requiring treatment □1:No, □2:Yes
Dialysis required □1:No, □2:Yes
Stroke □1:No, □2:Yes
New MI □1:No, □2:Yes
Intubation for 24hrs or more □1:No, □2:Yes
Return to OR □1: No, □2: Bleeding, □3: valve function failure,□4: Graft occlusion, □5: Other CV(cardiovascular)
disturbance, □6: Other
Mechanical circulatory Support devices
IABP □1: No,□2: Preop,□3: Intraop,□4: Postop
ECMO(PCPS) □1: No,□2: Preop,□3: Intraop,□4: Postop
VAS(VAD) □1: No,□2: Preop,□3: Intraop,□4: Postop
Total Artiﬁcial Heart □1: No,□2: Preop,□3: Intraop,□4: Postop
Indication□1: Hemodynamic instability, □2: Circulatory support on PTCA,□3: Unstable refractory angina, □4: CPB wean, □5: Prophylactic
indication, □6: Other, □7: Unknown

Post ope(In ICU)

Glu(mg/dL)
K(mEq/L)
Lact(mg/dL)
CRN(mg/dL)
TP(g/dL)
Hb(g/dL)pH
Po2(mmHg)
Pco2(mmHg)
HCO3-(mEq/L)
Svo2(%)

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per institution was 110 in the 2016 JACVSD report 9)
and this was mostly the same as the mean number(105) of extracorporeal circulation case registrations
per institution in the same year, suggesting that acohort study can be performed using the database in

gressed from a plan to the project and analytical studies. We
are grateful to clinical engineers, cardiovascular surgeons,data managers, executive members and councilors of JaSECT,
guideline formulation committee members, and executive
members of ICEBP and Perfusion Down Under for their support and contribution to the development of the registration.

which several thousands of extracorporeal circulation〈Appendices〉

cases are accumulated.
AmSECT was involved in preparation of the bloodtransfusion management guidelines established by
the collaboration of 2 academic societies, 10) and thetemperature management guidelines for extracorpo-

1. ‌Member of the Guidelines Formulation Committee（Year2009-2017）◦Makoto Hibiya, Fujita Health University, School of Health
Sciences◦Tetsuya Kamei, Fujita Health University, School of Healthreal circulation were prepared in 2015 by the collaboration of 3 academic societies.

11)

In addition, the regis-

tration items of extracorporeal circulation cases werereflected in the standard extracorporeal circulation
techniques published by AmSECT and guidelines, 12)
showing that the summation and analysis by the

Sciences◦Shoji Kubota, Asahikawa City Hospital◦Koji Takai, National Hospital Organization Nagoya Medical
Center
◦Shoichi Takado, Toyama University Hospital◦Hiroya Kano, Akashi Medical Center◦Yoshiaki Koyama, Saitama Children’s Medical Center

registration of extracorporeal circulation cases are◦Tomohiro Nakamura, Nagoya University Hospital

admitted as scientific evidence. Furthermore, after◦Mamoru Ieki, Kouseiren Takaoka Hospital

publication of the guidelines, it has been suggested
that the guidelines can be verified using the items ofthe data registered in the extracorporeal circulationcase database, 13) which also indicates that the regis-◦Noboru Ogoshi, Sendai Open Hospital◦Tetsuya Kakisaki, Medical Corporation Sapporo Heart Center◦Koichi Kanai, Hidaka Hospital◦Tomotaka Takeshima, Kochi Medical School Hospitaltration of extracorporeal circulation cases in JaSECT◦Seiji Tani, Mie University Hospital

may also contribute to preparation of cardiovascular◦Kazuyuki Nagata, Sakakibara Heart Institute of Okayama

surgery guidelines.
If all institutions participating in JACVSD participate in this project and registration of pediatric extra-◦Takayuki Nishigaki, Ministry of Economy, Trade and Industry◦Shin-ichi Nishida, Saitama Cardiovascular and Respiratory
Centercorporeal circulation cases is initiated, a cohort study◦Akira Hatanaka, Takanohara Central Hospitalusing the extracorporeal circulation case database◦Hiroshi Maeda, Sasebo Chuo Hospital

may progress and its achievement, scientific evidence,
may lead to stability and improvement of clinical extracorporeal circulation techniques and developmentof guidelines.
In Japan, a risk model was prepared using the case2. ‌Participate Institutions and Data-managers for the JaSECT
Perfusion Registry◦Akio Aramichi, Medical Corporation Sun Plaza Shin-Sapporo
Cardiovascular Hospital◦Tetsuya Kakizaki, Medical Corporation Sapporo Heart Cen-data accumulated in the JACVSDO database andJapanSCORE capable of calculating the predictedmortality before surgery in each case was published,leading to improvement of the quality of cardiovascular surgery. Since fewer extracorporeal circulationrelated items are included in JACVSD, the use ofdata accumulated in the extracorporeal circulationcase database is expected to improve the quality ofsurgery and lead to safe and appropriate medical carefor patients.

◦Shoji Kubota, Asahikawa City Hospital◦Toshifumi Matsumoto, National Hospital Organization Obihiro National Hospital◦Shin Taura, Nayoro City Hospital◦Toru Hirose, Mitsui Memorial Hospital◦Toru Yasuda, Jichi Medical University Saitama Medical
Center◦Shin-ichi Nishida, Saitama Cardiovascular and Respiratory
Center◦Kouichi Kanai, Hidaka-kai Group, Hidaka Hospital◦Makoto Anno, Gunma Cardiovascular Center〈Acknowledgments〉
This registration of extracorporeal circulation cases has pro-6

ter, Sapporo Cardiovascular Center◦Osamu Sagae, Hokkaido University Hospital

体外循環技術◦Takahiro Matsumura, Hokushin General Hospital◦Takeshi Kamizono, Shizuoka General Hospital

Vol.45

No.1

2018

Jpn J Extra-Corporeal Technology 45（1），2018

Centre and Alfred Hospital. Jpn J Extra-Corporeal◦Kengo Okitsu, Shizuoka City Shizuoka Hospital

Technol, 37（4）; 448-453, 2010.［Japanese］◦Mitsuru Sago, Medical Corporation Choshinkai Toyohashi

5） Hibiya M, Kamei T, Kenmoku K, et al.：A survey of theHeart Center◦Yasunori Yamamoto, Anjo Kosei Hospitalpresent status of perfusion in institutions with members◦Shigeyuki Ueda, National Hospital Organization Nagoyaof the Japanese Society of Extra-Corporeal Technology in
Medicine: Toward development of a perfusion database.

Medical Center

Jpn J Extra-Corporeal Technol, 39（2）；113-119, 2012.

◦Kazuhiro Goto, Nagoya University Hospital

6） Hibiya M, Kamei T, Kenmoku K, et al.：An Evaluation◦Masatoshi Kojima, Social Medical Corporation Daiyukai, Dai-

Trial of The National Perfusion Registry. J Extra Corpor

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◦Yoshihiro Otsubo, Ichinomiya Municipal Hospital

7） Kamei T, Hibiya M, Kenmoku K, et al.：A data analysis◦Tomoaki Yamashiro, Fujita Health University Hospitaltrial of the National Perfusion Registry in a pilot test. Jpn◦Yasuko Enya, Regional Independent Administrative Corpo-

J Extra-Corporeal Technol, 42（1）1-7, 2015.

ration Gifu Prefectural General Medical Center

8） Masuda M, Okumura M, Yokomise H, et al.：Thoracic◦Masaki Yoshida, University Hospital, Kyoto Prefectural Uni-and cardiovascular surgery in Japan during 2014: Annual

versity of Medicine

report by The Japanese Association for Thoracic Surgery.

◦Yoshitomo Kubo, Japan Labor Health and Welfare Organi-

Gen Thorac Cardiovasc Surg, 64（11）；665-697, 2016.

zation Osaka Rosai Hospital

9） Takamoto S, Motomura N, Tsukihara H, et al.：Current◦Akira Hatanaka, Takanohara Central Hospital◦Kazuyuki Nagata, Sakakibara Heart Institute of Okayama

Status of Cardiovascular Surgery in Japan, 2013 and 2014:◦Shota Yamamoto, Yamaguchi-ken Saiseikai Shimonoseki

A Report based on the Japan Cardiovascular Surgery
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General Hospital

J Cardiovasc Surg, 46（5）；187-190, 2017.［Japanese］◦Masanobu Tsurumoto, Tokushima Prefectural Central Hos-

10） Likosky DS, FitzGerald DC, Body SC, et al.：The effect ofpital◦Tomotaka Takeshima, Kochi Medical School Hospital

the perioperative blood transfusion and blood◦Chikara Okajima, Matsuyama Red Cross Hospitalconservation in cardiac surgery Clinical Practice◦Shinichiro Hara, National Hospital Organization Kyushu

Guidelines of the Society of Thoracic Surgeons and theSociety of Cardiovascular Anesthesiologists upon clinical

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◦Osamu Sakurai, Kanazawa University Hospital11） Engelman R, Baker RA, Hammon JW, et al.：The Societyof Thoracic Surgeons, The Society of Cardiovascular◦Yuji Kinoshita, National Hospital Organization Kanazawa

Anesthesiologists, and The American Society of

Medical Ceter◦Mamoru Ieki, Kouseiren Takaoka Hospital

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The authors declare that they have no COI.

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