PRODUCTCATALOG

2023

MICROFLUIDIC POETRY JULIEN RIDOUARD

WWW.ELVEFLOW.COM/MICROFLUIDIC-PRODUCTS/

ELVEFLOW PRODUCT CATALOG 2023 REF: PC23-0224

STATE OF THE ART

microfluidic instrumentation for all
Elveflow is an Elvesys brand. We build premium flow
handling instruments since 2012. We are proud tohave provided more than 2,000 systems so far toboth academics and industrial users.
Our product line is built around the best seller OB1 flow controller
and includes everything for accurate liquid handling. All our
instruments can be controlled simultaneously using our softwareand Software Development Kits allowing for a full automation ofyour system.
Our instruments are modular, upgradable and come in a standard
or OEM version.

CONTACT:ADDRESS:+33(0).184.163.807
contact@elveflow.com
www.elveflow.com

172 Rue de Charonne,
75011 Paris
FrancePRODUCTSFLOW CONTROL SYSTEMS
OB1 MK4

BEST SELLER

MULTI CHANNEL PRESSURE & VACUUM CONTROLLER

p.05

COBALT

AUTONOMOUS MICROFLUIDIC PUMP

p.11

MUX DISTRIB

12-WAY BIDIRECTIONAL VALVE

p.14

MUX RECIRCULATION

6-PORT/2-POSITION VALVE

p.16

MUX SERIESVALVES MATRICES

p.18

MUX WIRENEWVALVES & VALVE CONTROLLER

p.20

MEASUREMENT & DETECTIONMFS

MICROFLUIDIC FLOW SENSOR

p.23

BFS

PREMIUM FLOW SENSOR

p.26

MPS

LOW VOLUME PRESSURE SENSOR

p.31

MFP

LUER-LOCK PRESSURE SENSOR

p.33

MBD

MICROFLUIDIC BUBBLE DETECTOR

p.35

MSR
NEW

SENSOR READING UNIT

p.37

OEM & CUSTOM
OEM & CUSTOMORIGINAL EQUIPMENT MANUFACTURER & DESIGN STUDIO

p.10

SOFTWARE
ESI - FREE SOFTWAREELVEFLOW SMART INTERFACE - ALL INSTRUMENTS

p.39

FREE SOFTWAREACCESSORIESACCESSORIESRESERVOIRS, BUBBLE TRAP, TUBES HOLDER

p.39

PRESSURE SOURCECOMPACT PRESSURE SOURCE

p.41

VACUUM SOURCECOMPACT VACUUM SOURCE

p.43

MICROFABRICATIONBLACK HOLE LAB & ELVEFLOW MERGINGThe Black Hole Lab and Elveflow merged to provide a unique allin-one microfabrication setup. No need for cleanroom or experiencein microfabrication. Become autonomous in customizing your own
microfluidic devices in a short time.

STATION

SU-8 MOLD STATION

p.47

STATIONPDMS CHIPS STATION

p.48

APPLICATION PACKSMICROFLUIDICS PACKMICROFLUIDIC STARTER

p.50

MICROFLUIDICS PACKDROPLET GENERATION

p.51

MICROFLUIDICS PACKSEQUENTIAL INJECTION

p.52

NANOPARTICLE PACK

LIPID NANOPARTICLE SYNTHESIS

p.53

BIOLOGY PACKMEDIUM RECIRCULATION

p.54

BIOLOGY PACKORGAN-ON-A-CHIP

p.55

BIOLOGY PACKPERFUSION

p.56

ELVEFLOW OVERVIEW
Elveflow develops high-performance,plug-and-play flow control systems ideal
for microfluidic-based applications. We
provide the only microfluidic flow control
using Piezo technology that guarantees
fast flow changes in your microdevice.

ART DIRECTOR JULIEN RIDOUARD

contact@elveflow.com

MICROFLUIDIC POETRY,
an uncommon, conceptual and sensitive vision of the
microfluidic field, on the blurring border between art & science.
https://www.elveflow.com/microfluidic-tutorials/microfluidic-reviews-and-tutorials/microfluidic-poetry-unique-imaginative-sensitive-vision-microfluidics-field/

A TEAM OF MULTIDISCIPLINARY EXPERTS
Our assistance team comprises microfluidic
experts from different fields - engineers,
physicists, and biologists - to provide youwith specialized assistance. As a result, ourtechnology generated more than 1000 peerreviewed publications in chemistry, physics, andbiology, with more than 500 citations and ten
microfluidic patents.

MICROFLUIDICSINNOVATIONCENTER+

PRODUCTSFLOW CONTROLSYSTEMSPRODUCTS / FLOW CONTROL SYSTEMS

OB1 MK4

MULTI CHANNEL PRESSURE & VACUUM CONTROLLERELVEFLOW.COM/MICROFLUIDIC-FLOW-CONTROL-PRODUCTS/FLOW-CONTROL-SYSTEM/PRESSURE-CONTROLLER/

DON'T LET YOUR PUMP
LIMIT YOUR RESEARCHBEST RESPONSIVENESS
AND ACCURACY ON THE
MARKETRRANTYWAN TY

The OB1 MK4 is a high performancemicrofluidic pressure and flow controller.
Customize your unit: pick the number ofchannels you like and choose for each of them
the pressure and vacuum ranges among the 5options available.

A
ARR

BEST SELLERW

2 YEARSUNIQUE PERFORMANCES> Pressure stability 0.005 % FS
> Response time 9 ms
> Pressure resolution 0.006 % FS
> Settling time down to 50 ms

MODULARUPGRADABLESOFTWARE INCLUDEDFOR MICROFLUIDICSFREE SOFTWAREPIEZOELECTRICTECHNOLOGY

CUTTING EDGEPIEZO CONTROLAPPLICATIONS> Digital microfluidics> Flow chemistry & polymer synthesis> Cell culture: cell perfusion, sequential injection> Droplet-sequencing: RNA sequencing> Organ on chip
> Enhanced oil recovery> Lab on a chipwww.elveflow.com contact@elveflow.com +33(0).184.163.807
Elveflow, an Elvesys brand / ©2019 Microfluidic Innovation Center. All rights reserved. Information is subject to change without notice

CHOOSE FROM 1 TO 4
CHANNELS, AND MORE…
Get a one-channel today andadd more channels later6 | 57[GO TO SUMMARY]HOW IT WORKS

OB1 MK4

Flow controller
OB1 MK4

1

External pressure source

2

Sample3

Monitoring & sequencing

4

Microfluidic device

3. Monitoring &sequencing

Control the pressureor the ﬂow rate &automate sequences

Microfluidic flow sensor
MFS SENSOR

1. External pressuresourceConnect an externalpressure and/or avacuum source to
the OB1
Feedback loop mode

The pressure is adjustedwith a ﬂow rate sensor to
get the desired ﬂow rate
inside your setup

2. Pressurized

reservoir holder
rack

Microfluidic chip
4. Microﬂuidic device

The OB1 pressure &vacuum controller offers
the best performances
for perfect ﬂow control

Push your samples
into your microﬂuidic
device> To control flow rate or pressure at any given point of yourcircuit, you can perform a feedback loop with the flow rate. The
same can be done with pressure using a pressure sensor.

Connect a pressure and/or a vacuum
source to your OB1 (required).
Example: Gas cylinder, lab pressureline, compressor (see more p.40)

Depending on your choice, the liquids
can be pulled into the reservoir or bepushed from there since the OB1 canuse pressure or vacuum within thesame channel.

Automate pressure and flow control
using the Elveflow software on yourcomputer.

The OB1's pressure & vacuum
features offer precise sample
handling, and provide full control overthe injection.

FEATURES & BENEFITS• Short settling time
Operate blazing fast changes inany microdevice with our Piezo
technology• Software automation
Control all instruments througha single dashboard. Powerfulscript module to automate
control and injection over days

• Easy to install and use
Start out of the box and set
everything up within minutes• Highest flow stability
Ensure superior flow
performance over a large flow
range, with pressure stability
down to 10 µbar

• Accurate flow control
Input a flow value into thesoftware. Flow regulation
down to 7.5 nL/min• Create your own program • Enhanced data saving
Software Development Kits
(C++, Python, MATLAB® andLabVIEW® libraries)• Customizable
Choose from any numberof channels among the fivepressure ranges available

Up to 10 ms sampling rate totake out the best of your results• Upgradable
Get a one-channel today andadd more channels later

PRESSURE RANGES
0 to 200 mbar

FOR EACH CHANNEL:
5 PRESSURE RANGES AVAILABLE

0 to 2,000 mbar
0 to 8,000 mbar
-900 to 1,000 mbar
-900 to 6,000 mbar

www.elveflow.com contact@elveflow.com +33(0).184.163.807
Elveflow, an Elvesys brand / ©2019 Microfluidic Innovation Center. All rights reserved. Information is subject to change without notice

7 | 57[GO TO SUMMARY]TECHNICAL SPECIFICATIONS
OB1 MK4 CHANNELPRESSURE RANGE

OB1 MK4

0 to 200 mbar(1)(0 to 2.9 psi)

Pressure stability (2)0 to 2,000 mbar(1)0 to 8,000 mbar(1)(0 to 29 psi)

(0 to 116 psi)

0.015 % FS

0.005 % FS

0.006% FS

30 µbar (0.0004 psi)

100 µbar (0.0014 psi)

500 µbar (0.007 psi)

Response time (3)down to 10 ms

Settling time (4)down to 50 ms

Minimum pressure
increment-900 to 1,000 mbar(1) -900 to 6,000 mbar(1)(-13 to 14.5 psi)(-13 to 87 psi)

-900 to 500 mbar:-900 to 2,000 mbar:

0.005 % FS

0.005 % FS

100 µbar (0.0014 psi)

350 µbar (0.05 psi)

500 to 1,000 mbar:

2,000 to 6,000 mbar:

0.007 % FS

0.007 % FS

150 µbar (0.0021 psi)

525 µbar (0.076 psi)

0.006 % FS

0.006 % FS

0.006 % FS

0.0064 % FS

0.0061 % FS

12 µbar - 0,00017 ps

120 µbar - 0,0017 psi

480 µbar - 0,007 psi

120 µbar - 0,0017 psi

420 µbar -0.006 psi

1.5 bar (or Max pressure + 0.5 bar) to 10 bar
Non corrosive, non explosive, dry and oil-free gases, e.g. air, argon, N2, CO2, …

Pressure supply
Input vacuum (5)Any value from -0.7 to -1 bar
Compatible with vacuum pump or vacuum line/

Non contact pump
Any aqueous, oil, or biological sample solution.

Liquid compatibility

Non-contractual information, may be changed without notice.

POWER CONSUMPTION (maximum): 12 W

CASE DIMENSIONS (length x width x height): 240 x 223 x 80 mm

WEIGHT: 1.4 kg to 2.90 kg

TTL TRIGGER: In and out available 0-5V

(1) Max pressure value might vary by +/- 2.5% (2) Pressure stability (standard deviation) measured over the full pressure range with an external high accuracy pressure sensor (Druck DPI150) (3) Depending on your computer's operating
system (4) Volume dependent – Measurement done on 12 mL reservoir for a set point from 0 to 200 mbar (5) The vaccum channels can be used without vacuum source if only positive pressures are desired.

SENSITIVITY RAMP 21 mbar TO 23 mbar

FLOW CONTROL REACTIVITY(0.01 mbar steps)

High precision compared
to a syringe pump

mbar
24

EXTERNAL
MEASUREMENT

mbar
400

measured with an external high accuracypressure sensor (Druck DPI150)

300

22
200

20
0

ELVEFLOW

100

200

300

400

BEST SENSITIVITY
sec ON THE MARKET

CLOSEST COMPETITOR ON THE MARKET

100

0

10

20

30

40

sec

ELVEFLOW SYRINGE PUMP

They trust Elveflow's performances and quality:www.elveflow.com contact@elveflow.com +33(0).184.163.807
Elveflow, an Elvesys brand / ©2019 Microfluidic Innovation Center. All rights reserved. Information is subject to change without notice

8 | 57[GO TO SUMMARY]INSTRUMENT DESCRIPTION

OB1 MK4
Front view

PRESSURE RANGE COLOR CODE
Sensor connectors

YELLOW

0 to 200 mbar

Channel number
Pressure outlets

BLUE

0 to 2,000 mbar

PowerbuttonRear view

PURPLE

Screen-900 to 1,000 mbar
USB
socket5V trigger input/output
24V DC
adaptor socket

P/N: OB1-4-2200
Date: 08/22

External pressuresource connector
MAX INPUT PRESSURE: 10 Bar
VOLTAGE: 24 V / 1.5 A
DC
MADE IN FRANCEORANGE-900 to 6,000 mbar

GREY

0 to 8,000 mbar

External vacuum source connector (optional)

PRODUCTS & SERVICESELEMENTS PROVIDED BY ELVEFLOWINCLUDED

Software & libraries
Control all Elveflow instruments with the same smart interface•

Starter pack kit•

A complete set of accessories fitted for the OB1 flow generator

Reservoirs•

Gas tight reservoirs with ergonomic fluidic connection

Flow sensors•

A line of sensors to monitor very low liquid flow rates

Compressor•

A safe & secure pressure source for the OB1 pressure controller

Service
The Elveflow expertise & support to offer you individually tailored solutions

OPTIONAL•
Non-contractual information, may be changed without notice.

SOFTWARE FEATURES

ELVEFLOW.COM/MICROFLUIDIC-FLOW-CONTROL-PRODUCTS/FLOW-CONTROL-SYSTEM/ELVEFLOW-SOFTWARE/> Pressure & flow rate visualization and recording> Programming & automation of complex sequences> Easy alternative instrument control through the provided C++,
Python, MATLAB® and LabVIEW® libraries

National Instrument is our technological partner for
embedded electronics
More information:
ESI - FREE SOFTWAREELVEFLOW SMART INTERFACE - ALL INSTRUMENTS

www.elveflow.com contact@elveflow.com +33(0).184.163.807
Elveflow, an Elvesys brand / ©2019 Microfluidic Innovation Center. All rights reserved. Information is subject to change without notice

P.37

9 | 57[GO TO SUMMARY]PRODUCTS / FLOW CONTROL SYSTEMSOEM - ORIGINAL EQUIPMENT MANUFACTURER

CUSTOM FLUIDIC SYSTEMSELVEFLOW.COM/MICROFLUIDIC-FLOW-CONTROL-PRODUCTS/OEM-CUSTOM-FLUIDIC-SYSTEMS/A CUSTOM SOLUTIONTHAT FITS YOURPROJECT PERFECTLY

Elveflow provides a comprehensive line of OEM
fluidic components that can be integrated into
your products. Our OEM components allow
a seamless integration thanks to their small
footprint and easy interfacing. A simple serial
USB connection allows interfacing through ourAPI, the native in/out triggers provide optimum
interactions and we use standard fittings forpneumatic and fluidic connections.
We provide a dedicated software with all
fluidic OEM products, as well as libraries for acustomized software development (C++, Python,
MATLAB® and LabVIEW® libraries).

SERVICES> Personalized expert advice for our clientsand partners> Creation of technical specifications> Risk management and analysis> Development and production of mechanics,
electronics and software> Prototyping> Beta testing, troubleshooting andcontinuous improvement> Production, from limited series to large scale> Maintenance, support and training> Upgrades of your systems

WHY CHOOSE US AS YOUR OEM PARTNER?
> A receptive and efficient partner – We are well aware of the importance of keeping up with your fastchanging market.

> A soft intellectual property policy – We believe that intellectual property should never be an obstacle
to innovation.

> A trusted manufacturer – High profile companies already trust us for their scientific instruments. Why
not you?

> A proven track record – Our team carried out successfully several projects taking into accountchallenging constraints to end up with the best solutions for our partners.

www.elveflow.com contact@elveflow.com +33(0).184.163.807
Elveflow, an Elvesys brand / ©2019 Microfluidic Innovation Center. All rights reserved. Information is subject to change without notice

10 | 57[GO TO SUMMARY]PRODUCTS / FLOW CONTROL SYSTEMSCOBALT

AUTONOMOUS MICROFLUIDIC PUMPELVEFLOW.COM/MICROFLUIDIC-PRODUCTS/MICROFLUIDICS-FLOW-CONTROL-SYSTEMS/AUTONOMOUS-VACUUM-PRESSURE-PUMPS/

STANDALONEPRESSURE-DRIVENFLOW CONTROLLER

The Elveflow® Cobalt autonomous microfluidic
pump provides easy access to the moststable and accurate pressure and flow control
technology. Equipped with its own pressure(and vacuum) source, it does not require an
external pressure supply. Also, thanks to its
embedded software, It can be controlled itwith or without a computer.

UNIQUE PERFORMANCES*

MOST STABLE FLOW AND PRESSURE CONTROL

Available in two versions:

INTUITIVE USER INTERFACEPORTABLE AND COMPACT> pushing only: pressure range
0/2000 mbar
> push & pull: vacuum and pressure
range -900/1000 mbar

The Cobalt provides powerful flow control
when paired with a MFS flow sensor fromour product line:> Flow rate range from 200nL/min
to 5mL/min> Repeatability down to 3.5 nL/min> Accuracy down to 20 nL/min* All the values given for water.

APPLICATIONS> Lab-on-chip development> Bench test or characterisation (chips, sensors, filters, etc)
> Mechanobiology (cell confinement, tissue engineering, etc)
> Cell perfusionwww.elveflow.com contact@elveflow.com +33(0).184.163.807
Elveflow, an Elvesys brand / ©2019 Microfluidic Innovation Center. All rights reserved. Information is subject to change without notice

The cobalt is included in

THE MECHANOBIOLOGY PACK
www.elveflow.com/microfluidics-applicationpacks/biology-packs/mechanobiology-pack/

11 | 57[GO TO SUMMARY]HOW IT WORKSCOBALT> Plug it to a power source:
All you have to do is to turnon your Cobalt. The pressuresource is inside.

> Connect the reservoir:
No more pneumatic tubing
needed. You only have toplug your reservoir tothe instrument.

> Program and run yourexperiment:
Automate pressure andflow control using the 		
Elveflow embedded software,
no computer needed!

Choose between two Cobalt versions; both allow either gas or flow control when paired with a flow sensor.

> 0 to 2000 mbar positive pressure control.

> -700 to 1000 mbar dual vacuum & pressure control.

The Cobalt technology made state-of-the-art microfluidics accessible, autonomous, and user-friendly.

COBALT EMBEDDED SOFTWARE

Cobalt’s intuitive embedded
software can be fully controlled
without the need of external
computer. Its user-friendly
interface contains a knob button
for easy setting modifications.

OPTIONAL

COBALT COMPUTER SOFTWAREThe Cobalt® computer software allows you to control advanced tasks - suchas real-time creation, monitoring, and modifications of complex pressure andflow rate profiles - via computer using a USB connection.

www.elveflow.com contact@elveflow.com +33(0).184.163.807
Elveflow, an Elvesys brand / ©2019 Microfluidic Innovation Center. All rights reserved. Information is subject to change without notice

12 | 57[GO TO SUMMARY]TECHNICAL SPECIFICATIONSCOBALT

COBALT

COBALT DUAL

Push

Push & pull

0 to 2000 mbar
(0 to 29 psi)

-700 to 1000 mbar(-10 to 14 psi)

PNEUMATICS
Flow control
Pressure range (1)Minimum pressure
increment step

Cobalt Embedded Software (1 mbar)
Computer software (0.1 mbar)

Pressure stability (2)0.1 mbar

Electronic
response time

Cobalt Embedded Software: down to 10 ms
Computer software: down to 100 ms (3)Settling time (4)Down to 75 ms

Down to 105 ms

Pressure Source

No pressure source needed (integrated)

No pressure & vacuum source needed (integrated)

FLOW CONTROL
Flow sensor
compatibility

Possible to pair 1 flow sensor from the Elveflow MFS series (MFS2, 3, 4, 5)

Flow rates (5)MFS2: 0 to 7 µL/min | MFS3: 0 to 80 µL/min | MFS4: 0 to 1000 µL/min | MFS5: 0 to 5000µL/min

Minimum flowrate increment

MFS2: 3.5 nL/min | MFS3: 8 nL/min | MFS4: 0.2 μL/min | MFS5: 1 μL/min

Flow sensor
calibration

User-friendly automated sensor calibration module (6)Liquid compatibility

Non contact pump. Any aqueous or organic solvent, oil, or biological sample solution.
Recalibration required for non aqueous solutions at the bottem of the game

CONTROL & MONITORING
User interfaces

Cobalt Embedded Software
Cobalt computer software (Windows) on PC

Cobalt computer
software addedfunctionalities

Custom profile: design, upload, download
Recording data: download

Record frequency range

Cobalt Embedded Software: 1-5-10Hz
Computer software: 0-100Hz

Maximum recording time

Cobalt Embedded Software: up to 6000 sec depending on recording frequency
Computer software: unlimited

OTHER
Power consumption

36 W (100 V to 240 V - 50 Hz to 60 Hz)

Case dimensions
Weight

328 x 235 x 168 mm (l x w x h)
3.3 kgOutput connectors(1)

Max pressure value might vary by +/- 2.5%.

(2)Pressure stability (standard deviation) is measured
over 60s, 1 minute after the setpoint is reached.

4.1 kgQuick Connect

(3)
(4)

Depending on your computer's operating system.
Volume dependent – Measurement done on 12 mL reservoir for a set point from 100 to 200 mbar.

(5)

Indicative, please refer to the MFS documentation for detailed specifications.

(6)

For aqueous solutions only.

www.elveflow.com contact@elveflow.com +33(0).184.163.807
Elveflow, an Elvesys brand / ©2019 Microfluidic Innovation Center. All rights reserved. Information is subject to change without notice

13 | 57[GO TO SUMMARY]PRODUCTS / FLOW CONTROL SYSTEMSMUX DISTRIB

Included in our

12-WAY BIDIRECTIONAL VALVESEQUENTIAL FLUID INJECTION PACKELVEFLOW.COM/MICROFLUIDIC-PRODUCTS/MICROFLUIDICS-APPLICATION-PACKS/SEQUENTIAL-FLUID-INJECTION-PACK/ELVEFLOW.COM/MICROFLUIDIC-PRODUCTS/MICROFLUIDICS-FLOW-CONTROL-SYSTEMS/MUX-DISTRIB/A ROTARY VALVEDESIGNED TO EASILYEXECUTE FAST MEDIUM
SWITCHESThe Sequential Injection Valve is a bidirectional
13-port/12 way, which can control thesequential injection of one solution into twelve
different lines or twelve solutions into one line.

UNIQUE PERFORMANCES> Typical mechanical response time forport-to-port movement 156 ms> Easy setup: standard ¼-28 fluidic fittings

INJECTION OF UP TO 12 LIQUIDSNO CROSS CONTAMINATION> Lowest internal volume: 3.5 μL> High chemical compatibility (wetted
materials: PCTFE, PTFE)> Possibility to chose the sense of rotation

APPLICATIONS>Cell culture on chip>

Cell response to medium change>

Drug screening>

Toxicity tests>

Sensor testing & calibration>

Reagent switch for flow chemistrywww.elveflow.com contact@elveflow.com +33(0).184.163.807
Elveflow, an Elvesys brand / ©2019 Microfluidic Innovation Center. All rights reserved. Information is subject to change without notice

14 | 57[GO TO SUMMARY]HOW IT WORKSMUX DISTRIB
OB1Flow controller
MFS

Flow sensor

Manifold 9 ports

MUX Distrib

Reservoir holder rack

Setup

Distribution valve

Microﬂuidic chip

TECHNICAL SPECIFICATIONSMUX DISTRIBSPECIFICATIONSPort to port switching time (ms)

156 msMax. supported pressure

7 barInternal diameter

0.5 mmPerformances

Power supply

Input voltage range, AC

100 V to 240 V

AC supply frequency

50 Hz to 60 Hz

Max current consumption

2A peak

Power consumption (max)

36 W

Power supply voltage

18-24V DC
12 positions / 13 ports
rotative valve

Valve type
Fluidic connectors

Standard 1/4-28 UNF, flat-bottom

Operating temperature

5 °C to 40 °C

Mechanical specifications
Operating humidity

20-70% non condensing

Wetted materials

PCTFE and PTFE

Dead volume(1)None

Computer specifications

SoftwareUSB 2.0 port, Intel Pentium II 500 MHz, 1 Go Hard Disk space, 2 Go RAM Windows XP and newer,
32/64 bit. LabVIEW® 2011 is required when using LabVIEW® libraries.

Connection typeUSB

Provided elements

C++, Python, MATLAB® and LabVIEW® libraries(1) Volume that is stuck in the system (dead end), which is not clearly swept and relies on diffusion to clear out

MUX DISTRIB DIMENSIONS without connectors (length x width x height): 133 x 156 x 133 mm

www.elveflow.com contact@elveflow.com +33(0).184.163.807
Elveflow, an Elvesys brand / ©2019 Microfluidic Innovation Center. All rights reserved. Information is subject to change without noticeNon-contractual information, may be changed without notice.

15 | 57[GO TO SUMMARY]PRODUCTS / FLOW CONTROL SYSTEMSMUX RECIRCULATION

6-PORT/2-POSITION VALVE
ELVEFLOW.COM/MICROFLUIDIC-PRODUCTS/MICROFLUIDICS-FLOW-CONTROL-SYSTEMS/MUX-RECIRCULATION/

Included in our

RECIRCULATION PACKELVEFLOW.COM/MICROFLUIDIC-PRODUCTS/MICROFLUIDICS-APPLICATION-PACKS/
ONE-WAY-RECIRCULATION/

MAKE LONG-TERM
EXPERIMENTS EASIER
AND MORE RELIABLE

The Recirculation Valve is a 6-port/2 position
microfluidic valve allowing switching between
two configurations. It can be used in any
application that needs stable unidirectional fluid
recirculation and sample injection.

PRECISE VOLUME INJECTION
LONG RUN RECIRCULATIONUNIQUE PERFORMANCES> Recirculate a fluid in a closed loop
> Port-to-port switching time: 180 ms> High chemical compatibility (wetted
materials: PCTFE and PTFE)> No sample cross-contamination & nobackflow

POSITION AAPPLICATIONS> Cell culture on chip
> Drug screening

POSITION B> Toxicity tests> Stem cells assays> Organ on chip
> SPR or TIR imaging coupled with microfluidics> Heat sink experimentwww.elveflow.com contact@elveflow.com +33(0).184.163.807
Elveflow, an Elvesys brand / ©2019 Microfluidic Innovation Center. All rights reserved. Information is subject to change without notice

16 | 57[GO TO SUMMARY]HOW IT WORKSMUX INJ

Position A

Microfluidic
chip

Recirculation valve

MUX Recirculation

Position B

Microfluidic
chip

Recirculation valve

MUX Recirculation

Flow sensor

Flow sensor

MFS

MFS

Flow controller

Flow controller

OB1 MK4

OB1 MK4TECHNICAL SPECIFICATIONSMUX RECIRCULATIONSPECIFICATIONSPort to port switching time (ms)

180 msMax. recommended pressure

7 barInternal diameter

0.5 mmPerformances

Power supply

Input voltage range, AC

100 V to 240 V

AC supply frequency

50 Hz to 60 Hz

Max current consumption

2A peak

Power consumption (max)

36 W

Power supply voltage

18-24V DC

Valve type

6 ports / 2 positions rotative valve

Fluidic connector

Standard 1/4-28 UNF, flat-bottom

Operating temperature

5 °C to 40 °C

Mechanical specifications
Operating humidity

20 to 70 % condensing

Wetted materials

PCTFE and PTFE

Dead volume(1)None

Computer specifications

SoftwareUSB 2.0 port, Intel Pentium II 500 MHz, 1 Go Hard Disk space, 2 Go RAM Windows XP and newer,
32/64 bit. LabVIEW® 2011 is required when using LabVIEW® libraries.

Connection typeUSB

Provided elements

C++, Python, MATLAB® and LabVIEW® libraries(1) Volume that is stuck in the system (dead end), which is not clearly swept and relies on diffusion to clear out

MUX RECIRCULATION DIMENSIONS without connectors (length x width x height): 133 x 156 x 133 mm

www.elveflow.com contact@elveflow.com +33(0).184.163.807
Elveflow, an Elvesys brand / ©2019 Microfluidic Innovation Center. All rights reserved. Information is subject to change without noticeNon-contractual information, may be changed without notice.

17 | 57[GO TO SUMMARY]PRODUCTS / FLOW CONTROL SYSTEMSMUX SERIESFLOW SWITCH MATRICESELVEFLOW.COM/MICROFLUIDIC-FLOW-CONTROL-PRODUCTS/FLOW-CONTROL-SYSTEM/FLOW-MULTIPLEXER

3 UNIQUE FLOW SWITCH
MATRICES TO AUTOMATEFLOW HANDLINGCONTROL UP TO 16 VALVES INDEPENDENTLY
SMALL FOOTPRINTMUX CROSS CHIP

Stop the flow in microfluidic devices> Rocker peek valves> Plug & play programmable flow stop
> Complete equilibrium, stops flow in
100ms> Ultra low volume injection> Internal/external trigger> Fluidic connector: 10-32 UNF
APPLICATIONS: Instantaneous stop flow, small sample injection & sample premixing
WETTED MATERIAL: POM, Viton, PEEK, FKM

MUX FLOW SWITCH

Drug switch into microdevices> Rocker peek valves & PEEK manifold> Plug & play usb software> No samples cross-contamination & no>>>backflow
Flexible: from 4 to 256 valves
Internal/external trigger
Fluidic connector: 1/4-28 UNF

APPLICATIONS: Drug, reagent & cell medium switch for cell biology and flow chemistry
WETTED MATERIAL: PEEK, FKM

MUX QUAKE VALVEOpen & close bilayer PDMS valves> Plug & play programmable valve
>
>
>
>
>

sequence
Fast valve switch
Fine valve position tuning
Flexible: from 16 to 256 peek valves
Internal/external trigger
Fluidic connector: 10-32 UNF

APPLICATIONS: PDMS microvalves & micropumps and cell confinement device control
WETTED MATERIAL: POM, Viton, PEEK, FKM
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18 | 57[GO TO SUMMARY]TECHNICAL SPECIFICATIONSMUX SERIESMUX SERIESCROSS CHIP

FLOW SWITCH MATRIX

Valves actuation time

QUAKE VALVE

20 ms

Performances
Max. supported pressure

2 bar (29 PSI)

Input voltage range, AC

100 V to 240 V

AC supply frequency

50 Hz to 60 Hz

Input current, AC

1A

Power consumption

35 W

Power supply

Safety

IEC/EN 61010-1: 2001

Shutting down power supply

disconnect AC/DC adapter

Valve type
Input/output connectors

Mechanical specifications

Wetted materials

2/2-way solenoid valve
10-32 UNF

1/4-28 UNF

10-32 UNF

POM, Viton, PEEK, FKM

PEEK, FKM

POM, Viton, PEEK, FKM

Operating temperature

10 °C to 40 °C

Operating humidity
Computer specifications

Software

3/2-way solenoid valve

20 to 80 %USB 2.0 port, Intel Pentium II 500 MHz, 1 Go Hard Disk space, 2 Go RAM Windows XP and newer,
32/64 bit. LabVIEW® 2011 is required when using LabVIEW® libraries.

Connection typeUSB

Provided elements

C++, Python, MATLAB® and LabVIEW® libraries

MUX SERIES DIMENSIONS without connectors (length x width x height): 220 x 130 x 130 mm TTL TRIGGER: input/output 5 V

www.elveflow.com contact@elveflow.com +33(0).184.163.807
Elveflow, an Elvesys brand / ©2019 Microfluidic Innovation Center. All rights reserved. Information is subject to change without noticeNon-contractual information, may be changed without notice.

19 | 57[GO TO SUMMARY]PRODUCTS / FLOW CONTROL SYSTEMSVALVES RANGE & MUX WIREVALVES & VALVE CONTROLLERELVEFLOW.COM /MICROFLUIDIC-PRODUCTS/MICROFLUIDICS-FLOW-CONTROL-SYSTEMS/VALVE-CONTROLLER/

PLUG YOUR VALVESANYWHERE IN YOURMICROFLUIDIC SETUPMIX ALL KINDS OF VALVESPLUG FROM 1 TO 8 VALVESLIQUID INJECTION AUTOMATIONSMART LOW PRESSURE VALVE 2-WAY OR 3-WAY

2-WAY: Pick default setting: open or closed> Compatible with gas or liquid> ROCKER® valve technology> Low internal volume> Wide pressure range: -0.90 bar to 3 bar (-14 psi to 44 psi)
> Wetted Materials: PEEK, FKM, PVDF

SMART HIGH PRESSURE VALVE 2-WAY OR 3-WAY
2-WAY: Pick default setting: open or closed
>
>
>
>
>

Compatible with gas or liquid
ROCKER® valve technology
Low internal volume
Wide pressure range: -0.75 bar to 6 bar (-11 psi to 87 psi)
Wetted Materials: PEEK, FKM, PVDF

SMART LOW VOLUME VALVE 2-WAY>>>>

Compatible with gas or liquid
Low internal volume: 14.7 µL
Wide pressure range: 0 bar to 5 bar (0 psi to 73 psi)
Wetted Materials: PEEK, FKM, PVDF

MUX WIRE V3 VALVE CONTROLLER

Easily control your microfluidic valves> Fast liquid switching> Detect automatically all smart valves> Complex sequences of injection including flushing, rinsing, andsequential injection of several liquids

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20 | 57[GO TO SUMMARY]

2-WAY VALVE
2-WAY VALVEHOW ITMICROFLUIDICWORKS MICROFLUIDICMICROFLUIDIC
3-WAY
VALVE
MICROFLUIDIC
3-WAY
VALVE& VALVE CONTROLLERVALVESRANGE

MICROFLUIDIC 2-WAY VALVEMICROFLUIDIC 3-WAY VALVE

Pressure controller

Pressure controller

Pressure controller OB1
OB1

USB
Valve controller
MUX WIRE

USB

USB

USB
Valve controller
MUX WIRE

Low volume
valve 2/2

Low volume
valve 2/2

Pressure controller
OB1
OB1

Valve controller
MUX WIRE

Valve controller
MUX WIRE

Low pressure valve
3/2

Microfluidic chip

Reservoir
Low pressure valve
Sample3/2
1

Reservoir
Sample Microfluidic chip

Microfluidic chip

Microfluidic chip

Reservoir
Sample 1

Reservoir
SampleReservoir
Sample 2

TECHNICAL SPECIFICATIONS

Reservoir
Sample 2

VALVES RANGE
Low pressure valve-0.90 bar to 3 bar (-14 psi to 44 psi)
Fittings: Standard 1/4-28"
Switching time: <10 ms

High pressure valve-0.75 bar to 6 bar (-11 psi to 87 psi)
Fittings: 10-32
Switching time: 15 ms

VALVES TYPE

2-way
Normally open
Internal volume: 25 µL

2-way
Normally closed
Internal volume: 25 µL

3-way
Internal volume: 32 µL

2-way
Normally open
Internal volume: 55.5 µL

2-way
Normally closed
Internal volume: 55.5 µL

3-way
Internal volume: 58.25 µL

Low volume valve

2-way
Normally closed
Internal volume: 14.7 µL

0 bar to 5 bar (0 psi to 73 psi)
Fittings: 10-32
Switching time: 20 ms

Non-contractual information, may be changed without notice.

VALVES DIMENSIONS without connectors (length x width x height): LOW & HIGH PRESSURE: 52 x 34 x 80 mm

VALVE CONTROLLERLOW VOLUME: 57 x 34 x 51 mm

SPECIFICATIONS

Number of controlled valves8

Bus interface

USB

Power supply

18-24, 1.5 A

Max total power

36 W

Max valve power

10 W

Valve connectors

USB-C(sum of the power of all connected valves)

Non-contractual information, may be changed without notice.

VALVE CONTROLLER DIMENSIONS without connectors (length x width x height): 140 x 96 x 35 mm

WEIGHT: 374 g TTL TRIGGER: input/output 5 V

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Elveflow, an Elvesys brand / ©2019 Microfluidic Innovation Center. All rights reserved. Information is subject to change without notice

21 | 57[GO TO SUMMARY]PRODUCTS

MEASUREMENT &DETECTION

PRODUCTS / MEASUREMENT & DETECTIONMFS

THERMAL BASED FLOW SENSOR
ELVEFLOW.COM/MICROFLUIDIC-FLOW-CONTROL-PRODUCTS/MICROFLUIDIC-FLOW-CONTROL-MODULE/MICROFLUIDIC-LIQUID-MASS-FLOW-SENSORS/

HIGH-ACCURACY
FLOW MONITORING
AND CONTROL

High-accuracy volumetric flow sensors forultra-low flow rate monitoring of liquids. The
thermal-based flow sensor comes with an M84-pin electrical connection and can be directly
controlled through the Elveflow software.

5 FLOW RATE RANGESHIGH CHEMICAL COMPATIBILITYUNIQUE PERFORMANCES> Calibrated flows from 0.07 μL/min to
5,000 μL/min> Sensor response time: 40 ms> Resolution down to 1.5 pL/s
> Wetted materials: glass or quartz

PRINCIPLE
straight flow channel

APPLICATIONS> Couple with an OB1 flow controller for directflow rate control> Bi-directional flow rate measurement(positive & negative)

www.elveflow.com contact@elveflow.com +33(0).184.163.807
Elveflow, an Elvesys brand / ©2019 Microfluidic Innovation Center. All rights reserved. Information is subject to change without noticetemperature
sensortemperature
sensorheater23 | 57[GO TO SUMMARY]HOW IT WORKSMFS

WITH ELVEFLOW FLOW CONTROLLERS: MONITORING + CONTROL

Microfluidic pump

WITH SENSOR READER: MONITORING

Flow controller

AF1 SERIES

Sensor reader

OB1 MK3+

MSR

Microfluidic flow sensor
MFS SENSOR

Microfluidic flow sensor

Microfluidic flow sensor

MFS SENSORMFS SENSOR

Microfluidic chip

Microfluidic chipPressurized reservoir
SampleMicrofluidic chipPressurized reservoir
SampleTECHNICAL SPECIFICATIONSMFS FLOW RATE RANGES AND ACCURACY

Accuracy with water / aqueous
solutions calibration:

10 µL/min

5 % m.v.

Accuracy with IPA calibration:

100 µL/min

20 % m.v.

m.v. - measured value

MFS5

5 % m.v.

10 µL/min

200 µL/min

5 mL/min

500 µL/min

10 mL/min

100 µL/min

20 % m.v.

2 µL/min

MFS4

5 % m.v.

40 µL/min

1 mL/min

25 µL/min
5 µL/min
120 nL/min

80 µL/min

4.2 µL/min
210 nL/min

70 µL/min
20 % m.v.

20 nL/min

MFS2

5 % m.v.

420 nL/min

7 nL/min

7 µL/min

10 % m.v.

75 nL/min

1 nL/min

MFS3

5 % m.v.

2.4 µL/min

0500 µL/min
20 % m.v.

10 nL/min

100 nL/min

MFS1
1.5 µL/min

1 µL/min

10 µL/minwww.elveflow.com contact@elveflow.com +33(0).184.163.807
Elveflow, an Elvesys brand / ©2019 Microfluidic Innovation Center. All rights reserved. Information is subject to change without notice

100 µL/min

1 mL/min

10 mL/min

Flow rate

24 | 57[GO TO SUMMARY]TECHNICAL SPECIFICATIONSMFS FLOW SENSORS

MFS
MFS 1

MFS 2

MFS 3

MFS 4

MFS 5

Media calibrationwater / aqueous
solutionswater /
aqueoussolutions

IPA

water /
aqueoussolutions

IPA

water /
aqueoussolutions

IPA

water / aqueous
solutions

Flow rate range

0 to ± 1.5µL/min0 to ± 7µL/min0 to ± 70µL/min0 to ± 80µL/min0 to ± 500µL/min0 to ± 1
mL/min0 to ± 10
mL/min0 to ± 5
mL/min

7 nL/min

20 nL/min

120 nL/min

2 µL/minbetween[0 to 4.2]
µL/minbetween[0 to 2.4]
µL/minbetween[0 to 25]
µL/minbetween[0 to 0.04]
mL/min100 µL/min

10 µL/min

between[0 to 0.42]µL/min

210 nL/min

5 µL/minbetween[0 to 75]
nL/min

10 % m.v.

5 % m.v.

20 % m.v.

5 % m.v.

20 % m.v.

between[75 to 1,500]
nL/minbetween[0.42 to 7]µL/minbetween[4.2 to 70]µL/minbetween[2.4 to 80]µL/minbetween[25 to 500]
µL/min

0.9 nL/min

3.5 nL/min

7 nL/min

8 nL/minbetween[0 to 1.4]
µL/minAccuracym.v. - measured value
applies to negative values(bi-directional)

Repeatability
m.v. - measured value
applies to negative values(bi-directional)

Pressure dropat full scale flow rate, 23 °C

between[0 to 0.5]
mL/minbetween[0 to 200]
µL/min5 % m.v.

20 % m.v.

5 % m.v.

between[0.04 to 1]
mL/minbetween[0.5 to 10]
mL/minbetween[0.2 to 5]
mL/min0.25 µL/min

0.2 µL/min

5 µL/min

1 µL/minbetween[0 to 25]
µL/minbetween[0 to 0.04]
mL/minbetween[0 to 0.5]
mL/minbetween[0 to 0.2]
mL/minbetween[0 to 80]nL/minbetween[0 to 0.7]
µL/minbetween[0 to 0.7]
µL/min< 1 % m.v.

0.5 % m.v.

1 % m.v.

0.5 % m.v.

1 % m.v.

0.5 % m.v.

1 % m.v.

0.5 % m.v.

between[80 to 1,500]
nL/minbetween[0.7 to 7]µL/minbetween[0.7 to 70]µL/minbetween[1.4 to 80]µL/minbetween[25 to 500]
µL/minbetween[0.04 to 1]
mL/minbetween[0.5 to 10]
mL/minbetween[0.2 to 5]
mL/min1 bar

3 mbar

60 mbar1 mbar

7 mbar< 1 mbar

5 mbar< 1 mbar

Total internal volume

1 µL

1.5 µL

5 µL

25 µL

80 µL

Sensor inner diameter

25 µm

150 µm

430 µm

1.0 mm

1.8 mm29 mm

Tubing inner length
Operating pressure

200 bar

100 bar

15 bar

15 barBurst pressure

400 bar

200 bar

30 bar

30 barMicrofluidic fitting typeUNF 1/4-28

Wetted material

PEEKInternal sensor capillarymaterial

QuartzBorosilicate glass

Non-contractual information, may be changed without notice.

ELECTRICAL INPUT: 8V

7 mA

ANALOG OUTPUT: 0 - 5 V

FLOW SENSOR SIZE (length x width x height): 58 x 52 x 23 mm

WEIGHT: 102 g

Excellent chemical resistance and bio-compatibility are ensured					The recommended storage temperature ranges from -10°C to +60°C
Liquid Flow Sensor enables fast, and non invasive measurements of very low liquid flow rate below 5mL/min		
The operating temperature is +10°C to +50°C
The product comes fully calibrated for water 						The flow sensor shows bi-directional and linear transfer characteristics
Flow calibration for methanol or other media is available on request (all data for medium H2O, 20°C, 1 bar unless otherwise noted)

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25 | 57[GO TO SUMMARY]PRODUCTS / MEASUREMENT & DETECTION

BFS

CORIOLIS BASED FLOW SENSOR
ELVEFLOW.COM/MICROFLUIDIC-FLOW-CONTROL-PRODUCTS/MICROFLUIDIC-FLOW-CONTROL-MODULE/MICROFLUIDIC-FLOW-SENSOR-CORIOLIS/

COMPATIBLE WITH ALL
LIQUIDS: WATER, OIL,
ALCOHOL, MIXTURE, AND
MORE. NO CALIBRATIONREQUIRED

In partnership with Bronkhorst, we havedeveloped a unique Coriolis flow sensor suited tomicrofluidics. It offers various benefits: precision,
wide range, straightforward compatibility withall liquids (no calibration needed).

COMPATIBLE WITH ALL LIQUIDS & GAS
NO CALIBRATION NEEDEDAPPLICATIONS>

Coumpound semiconductor processing>

Solar cell and FDP technology>

Food and pharmaceutical industries>

Medical microchemical or analyticalinstallations>

Calibration laboratories

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Elveflow, an Elvesys brand / ©2019 Microfluidic Innovation Center. All rights reserved. Information is subject to change without notice

UNIQUE PERFORMANCES> Large flow range from 1.6 µL/min to
500 mL/min (for water)> Maximum flow rate: 500 mL/min (for water)> Sensor response time: 35 ms> Mass flow accuracy: down to 2 % of
measured value (down to 0.2 % of mv
on request)

PRINCIPLE

26 | 57[GO TO SUMMARY]HOW IT WORKS

BFS

WITH ELVEFLOW FLOW CONTROLLERS: MONITORING + CONTROL

Microfluidic pump

WITH EXTERNAL EQUIPMENT: MONITORING

Flow controller

AF1 SERIESOB1 MK3+

USB

USB

USB

Coriolis flow sensor
BFS SENSOR

Coriolis flow sensor

Coriolis flow sensor

BFS SENSOR

BFS SENSOR

Microfluidic chip

Microfluidic chipPressurized reservoir
SampleMicrofluidic chipPressurized reservoir
SampleTECHNICAL SPECIFICATIONSCORIOLIS FLOW SENSOR

BFS 1

Flow range

BFS 1+

0.1 g/h to 200 g/h

BFS 2

BFS 3

1 g/h to 2000 g/h

30 g/h to 30000 g/h

Minimum flow rate (water)

1.6 µL/min

16.6 µL/min

500 µL/min

Maximum flow rate (water)

3.3 mL/min

33.3 mL/min

500 mL/min

PERFORMANCE
Mass flow accuracy liquids

down to ± 2 % of measured value

down to ± 0.2 % of measured value

Mass flow accuracy gases

up to ± 0.5 % o measured value

Repeatability± 0.05 % of rate ± 1/2 (ZS* x 100/flow) % based on digital output

Zero stability (ZS) (1)< ± 0.01 g/h

Density accuracy< ± 5 kg/m

Temperature accuracy
Temperature effect (2)< ± 0.2 g/h< ± 6 g/hZero drift: ± 0.02 g/h/°C

Zero drift: ± 0.5 g/h/°C

3± 0.5 °C
Zero drift: ± 0.01 g/h/°C

Mounting (3)Any position, attitude sensitivity negligible

Device temperature

0...70 °C

Response time (t 98 %)0.2 s to fill the tubing then 35 ms

MECHANICAL PARTS
Stainless steel 316 L or comparable

Wetted material

Stainless steel 316 L or comparable

Pressure rating

200 barSensor inner diameter

250 µmSuitable tubings

1/16"

Internal volume

13 µL

Calibration

Optional: Hastelloy-C22/

FLOW SENSOR SIZE (length x width x height): 65 x 32 x 144 mm

Optional: Hastelloy-C23

200 bar; higher on request
0.5 mm

1.3 mm1/16" (1/8" on request)

0.45 mL

0.82 mL

Individual calibration certificate

WEIGHT: 3 kg

Non-contractual information, may be changed without notice.

(1) Guaranteed at constant temperature and for unchanging process and environment conditions. (2) Depends on flow rate, heat capacity fluid, T amb., T fluid and cooling capacity.
(3) To be rigidly bolted to a stiff and heavy mass or construction for guaranteed stability. External shocks or vibrations should be avoided.

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Elveflow, an Elvesys brand / ©2019 Microfluidic Innovation Center. All rights reserved. Information is subject to change without notice

27 | 57[GO TO SUMMARY]TOTAL ERROR (% m.v.)

BFS

TOTAL ERROR = ACCURACY READING ± [(ZERO STABILITY / FLOW) X 100] [% READING]

m.v. - measured value

BFS 1+

10

Total error (% m.v.)

Total error (% m.v.)

10
8
6
4

8
6
4
2

2

10-5

10-4

0.1

10-3

1

10

100

Mass flow rate (g/h) - log scale

Volume flow rate (L/min) - log scalewater at 20 ° C

BFS 2

20

Total error (% m.v.)

Total error (% m.v.)

20

15

10

5

0

10-4

10-3

15

10

5

0

10-2

1

10

100

1,000

Mass flow rate (g/h) - log scale

Volume flow rate (L/min) - log scalewater at 20 ° C

BFS 3
20

Total error (% m.v.)

Total error (% m.v.)

20

15

10

5

0

10-3

10-2

10-1

Volume flow rate (L/min) - log scale

15

10

5

0

100

1,000

10,000Mass flow rate (g/h) - log scalewater at 20 ° C

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28 | 57[GO TO SUMMARY]BFS FLOW SENSOR PRESSURE DROP (FOR WATER @20°C)

www.elveflow.com contact@elveflow.com +33(0).184.163.807
Elveflow, an Elvesys brand / ©2019 Microfluidic Innovation Center. All rights reserved. Information is subject to change without notice

BFS

29 | 57[GO TO SUMMARY]FLOW SENSORS COMPARISON MFS VS BFS

FLOW SENSORSCOMPARISON

BFS (1 & 1+)

MFS

Accuracy

0.2 % of measured value (1)5 % of measured value

Range

One sensor for 1.6 µL/min to
3 mL/minFive sensors from
10 nL/min to 5 mL/min

Yes

Yes

All without calibration

All with calibration

Response time

35 ms (2)From 1 to 70 ms (3)Flow sensor size

65 x 32 x 144 mm

58 x 53 x 23 mm

Internal diameter

250 µmFrom 25 µm to 1.8 mm (4)

3 kg

100 g

1/16" OD tubing

1/16" OD tubing

Internal volume

13 µL

From 1 µL to 80 µL(4)Wetted material

Stainless steel 316L orcomparable

Glass or Quartz

Coriolis

ThermalComputer connection

Directly via USB to thecomputerDirectly on the OB1 and the AF1
or with the Sensor reader MSR

Additional features

Temperature and density
measurement

Negative flow
measurement
Supported fluid types

WeightConnectors

Principle

Non-contractual information, may be changed without notice.

(1) Available upon request. 2 % accuracy for the regular model(2) 0.2 s at 98 % (spec) to fill the tubing then 35 ms with temperature measurement(3) Depending on chosen digital resolution(4) Depending of the sensor range

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30 | 57[GO TO SUMMARY]PRODUCTS / MEASUREMENT & DETECTIONMPS

LOW VOLUME PRESSURE SENSOR
ELVEFLOW.COM/MICROFLUIDIC-FLOW-CONTROL-PRODUCTS/MICROFLUIDIC-FLOW-CONTROL-MODULE/MICROFLUIDIC-LIQUID-FLOW-THROUGH-PRESSURE-SENSOR/MEASURE AND
CONTROL PRESSURE
ANYWHERE IN YOURSETUPHigh accuracy pressure sensor adapted to liquidand gas and compatible with 3/32" ID tubing
or 10-32 fittings for 1/16" OD tubing. Ideal
for monitoring low pressure flow rate in yourmicrofluidic setup.

UNIQUE PERFORMANCES> Accuracy down to 0.2 % FS
> 5 ranges from 70 mbar to 7,000 mbar
> Internal volume: 7 μL
> Settling time: 20 ms

PRESSURE FEEDBACK OPTIONMEASUREMENT & DETECTION> Works with both liquid & gas

APPLICATIONS> By plugging our pressure sensor anywhere in your microfluidic setup, you can record thepressure on your computer and adjust it accordingly using our pressure pumps

OUR PRESSURE SENSORS WORK ASGAUGE PRESSURE SENSORS,
measuring positive and negative pressure relatively to atmosphericpressure.

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Elveflow, an Elvesys brand / ©2019 Microfluidic Innovation Center. All rights reserved. Information is subject to change without notice

31 | 57[GO TO SUMMARY]TECHNICAL SPECIFICATIONSMICROFLUIDIC PRESSURESENSOR

Pressure range
Maximum overpressure

MPS 0

MPS 1

MPS 2

MPS 3

MPS 4

-70 to 70 mbar

-340 to 340 mbar

-1 to 1 bar-1 to 2 bar-1 to 7 bar(-1 to 1 psi)(-5 to 5 psi)(-15 to 15 psi)(-15 to 30 psi)(-15 to 100 psi)

3 bar (45 psi)

3 bar (60 psi)

14 bar (200 psi)

1.4 bar (20 psi)

1.4 bar (20 psi)

up to ± 0.5 % of max range

up to ± 2 % of max range

Typical

0.25

0.4

0.25

0.1

0.4

Max.

0.5

0.5

0.5

0.2

0.6

± 3.0

± 0.4

Pressure accuracy liquids
Linearity
%span

MPS

Repeatability & hysteresis%span

up to ± 0.2 % of max range± 0.2

Operating temperature-40 °C to +85 °C

Specified temperature range

0 °C to +50 °C
Non-contractual information, may be changed without notice.

PACKAGE MODEL

LARGE

SMALL

Connection type3/32 barb

10-32 thread with ferruleInternal volume

70 µL

7.5 µL

Recommended tubing
diameter (inch)

3/32" ID

1/16" OD

polyetherimide, silicon and fluorosilicone seal

PEEK, silicon and fluorosilicone seal

Sensor design

Wetted materials
Electrical connection

4 point measurement M8 connector compatible with Elveflow Sensor Reader and a Sensor Reader

SENSOR SIZE (length x width x height): LARGE: 29 x 13 x 27 mm SMALL: 40 x 33 x 19 mm

AMPLIFICATION MODULE SIZE: 52 x 24 x 24 mm

WITH ELVEFLOW PRESSURE CONTROLLERS: MONITORING + CONTROL

Microfluidic pump

Flow controller

AF1 SERIES

Non-contractual information, may be changed without notice.

WITH SENSOR READER: MONITORING

Sensor reader

OB1 MK3+

MSR

Microfluidic pressure sensor
MPS SENSOR

Microfluidic pressure sensor

Microfluidic pressure sensor
MPS SENSOR

Microfluidic chip

Microfluidic chip

Microfluidic chipPressurized reservoir
SampleMPS SENSOR

Pressurized reservoir
Samplewww.elveflow.com contact@elveflow.com +33(0).184.163.807
Elveflow, an Elvesys brand / ©2019 Microfluidic Innovation Center. All rights reserved. Information is subject to change without notice

32 | 57[GO TO SUMMARY]PRODUCTS / MEASUREMENT & DETECTION

MFP

LUER-LOCK PRESSURE SENSOR
ELVEFLOW.COM/MICROFLUIDIC-FLOW-CONTROL-PRODUCTS/MICROFLUIDIC-FLOW-CONTROL-MODULE/MFP-MICROFLUIDIC-INLINE-PRESSURE-SENSOR/MEASURE AND
CONTROL PRESSURE
OVER A LARGE RANGE

Flow-through pressure sensors adapted togases or liquids, and compatible with the Luerlock standard. The flowplus fluid sensor isintended to measure the pressure of fluid media
flowing through the sensor.

UNIQUE PERFORMANCES> Accuracy up to 2 % FS
> 1 ranges 0 - 16 bar - Overlay 25 bar>

No dead volume> Flow rate up to 100 mL/min

HIGH CHEMICAL COMPATIBILITYUP TO 16 BAR> Versatile: works with gas & liquid

APPLICATIONS> You can plug our pressure sensor anywhere within your microfluidic setup, record the pressure
on your computer and adjust the pressure or flow accordingly using our pressure pumps.

WIDE MEDIA COMPATIBILITY(material in contact: FFKM) FDA-certified and therefore, suitable forfood industry use.

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33 | 57[GO TO SUMMARY]TECHNICAL SPECIFICATIONS

MFP

LUER-LOCK PRESSURE SENSORSPECIFICATIONS

Maximum flowrate (1)100 mL/min

Pressure range

0 to 16 bar

Power supply

12 to 30 VDC

Wetted materials

interior flow channel: FFKM

Housingcoated aluminum

Output signal

0.1 to 10 V

Electrical connection“push-pull” connector / M8 sensor plug

Mechanical connection

LUER-LOCK DIN EN 1707

Temperature range

15 to 45 °C

Internal volume

205 µL
inner diameter: between 4 mm and 1.8 mm
length: 31.2 mm

Dimensions

Non-contractual information, may be changed without notice.

(1) Depends on the viscosity and primary pressure of the medium

SENSOR SIZE (length): 31.2 mm

OUR PRESSURE SENSORS WORK AS GAUGE PRESSURE SENSORS,
measuring pressure relatively to atmospheric pressure.

WITH ELVEFLOW FLOW CONTROLLERS: MONITORING + CONTROL

Microfluidic pump

WITH SENSOR READER: MONITORING

Flow controller

AF1 SERIES

Sensor reader

OB1 MK3+

MSR

Microfluidic pressure sensor
MFP SENSOR

Microfluidic pressure sensor
MFP SENSOR

Microfluidic pressure sensor
MFP SENSOR

Microfluidic chip

Microfluidic chip

Microfluidic chipPressurized reservoir
SamplePressurized reservoir
Samplewww.elveflow.com contact@elveflow.com +33(0).184.163.807
Elveflow, an Elvesys brand / ©2019 Microfluidic Innovation Center. All rights reserved. Information is subject to change without notice

34 | 57[GO TO SUMMARY]PRODUCTS / MEASUREMENT & DETECTIONMBD

MICROFLUIDIC BUBBLE DETECTORELVEFLOW.COM/MICROFLUIDIC-FLOW-CONTROL-PRODUCTS/MICROFLUIDIC-FLOW-CONTROL-MODULE/MICROFLUIDIC-LIQUID-SENSOR/CHECK IF LIQUID IS
PRESENT IN CLEAR
TUBING

This sensor detects the presence of fluids
inside clear tubing, triggers a signal to another
instrument, and acts as needed - stop, wait,
allow enough flow to clear the tubing, or reset
the sensor.

UNIQUE PERFORMANCES> Cost-effective compared to camera> Based on true/false logic> Reliable non invasive technique

BUBBLE MONITORING
LIQUID INTERFACES DETECTION> Prevents damage in cells with bubble
bursts> The microfluidic bubble detector comesin two different casings suited to theuse with 1/16″ or 1/4″ outside diameter
tubes

APPLICATIONS> Bubble detection> Liquid level sensing> Blood processing equipment> Patient connected medical devices> Perform bilateral recirculation based on air detectionwww.elveflow.com contact@elveflow.com +33(0).184.163.807
Elveflow, an Elvesys brand / ©2019 Microfluidic Innovation Center. All rights reserved. Information is subject to change without notice

35 | 57[GO TO SUMMARY]TECHNICAL SPECIFICATIONS

MBD

DETECTION MODULE SIZE (length x width x height): 68 x 29 x 33 mm AMPLIFICATION MODULE SIZE: 69 x 59 x 22 mm

HOW IT WORKS
A light beam is emitted by a LED at known power. This light beam goes throughthe capillary and the fluid passing through. It is then collected by an NPN silicon
phototransistor. This phototransistor converts the light power into an electrical power.
When a fluid changes, the optical index and the light absorption coefficient change
accordingly. It induces a change in the electrical power and allows to detect changes in thefluid.

WAVELENGTH = 890 nm

www.elveflow.com contact@elveflow.com +33(0).184.163.807
Elveflow, an Elvesys brand / ©2019 Microfluidic Innovation Center. All rights reserved. Information is subject to change without notice

36 | 57[GO TO SUMMARY]PRODUCTS / MEASUREMENT & DETECTIONMSRSENSOR READING UNIT
ELVEFLOW.COM/MICROFLUIDIC-PRODUCTS/MICROFLUIDICS-FLOW-MEASUREMENT-SENSORS/MICROFLUIDIC-SENSOR-READER/

AN ACQUISITION
INTERFACE FOR ALL
SENSORSThe sensor reader is an interface allowing theacquisition of many kinds of analog & digitalsensors, including Elveflow pressure sensors
and flow sensors.

UNIQUE PERFORMANCES> Fast acquisition frequency 1 kHz> From 9 to 16 bits resolution> Real-time control & feedback loops

MONITOR UP TO 4 SENSORSREAL-TIME CONTROL & FEEDBACK> Read simultaneously up to 4 sensors

APPLICATIONS> The Sensor Reader can be used to monitor flow rate, pressure, or other physical parameters
on any type of flow control instrument (syringe pump, peristaltic pump, perfusion, pressure
controller)> It embeds two independent power supplies which allows the use of a wide variety of sensors
simultaneousy, functionning with different voltages for their power supply

www.elveflow.com contact@elveflow.com +33(0).184.163.807
Elveflow, an Elvesys brand / ©2019 Microfluidic Innovation Center. All rights reserved. Information is subject to change without notice

37 | 57[GO TO SUMMARY]TECHNICAL SPECIFICATIONSMSRSENSOR READER UNIT

SPECIFICATIONS

Number of sensors

4

Sensor connectors

M8 female (4 pins)

USB reading current min - max

200 mA - 800 mA

Sensor power supplies voltage(2 power supplies tunable independently each of which
feeding 2 sensors)

5 - 24 V

Total power on the 4 channels

0.9 W

SENSOR INPUTS
Impedance

1 MΩ

Acquisition frequency

200 HzAcquisition resolution

from 9 to 16 bits

Input range

0 - 10 V

Resolution (1 bit)

5 mV

Noise (full band)

5 mV rms

Compatible sensors

MFS flow sensor, MPS pressure sensor, MFP FlowPlus pressure sensor, MBD bubble detector

SENSOR READER SIZE without connectors (length x width x height): 91 x 69 x 29 mm

WEIGHT: 320 g

www.elveflow.com contact@elveflow.com +33(0).184.163.807
Elveflow, an Elvesys brand / ©2019 Microfluidic Innovation Center. All rights reserved. Information is subject to change without noticeNon-contractual information, may be changed without notice.

38 | 57[GO TO SUMMARY]PRODUCTS / SOFTWAREESIELVEFLOW SOFTWAREELVEFLOW.COM/MICROFLUIDIC-FLOW-CONTROL-PRODUCTS/FLOW-CONTROL-SYSTEM/ELVEFLOW-SOFTWARE/

ESI - ELVEFLOW
SMART INTERFACEA UNIQUE SOFTWARE
FOR ALL INSTRUMENTS

DIRECTLY INPUT FLOW RATECUSTOM FLOW PROFILEADVANCED WORKFLOW AUTOMATION

Elveflow Smart Interface allows an intuitive control of our
microfluidic instruments in a few clicks. It is designed bothfor basic control and complex tasks thanks to the use of
the scheduler.
The ESI microfluidic software makes many applications
easy, such as: generation of continuous fluid streams,
dosing of volumes, generation of dynamic flow profiles,
Optomicrofluidic control, and many more…

National Instrument is our technological partner
for embedded electronics

FEATURES THAT MATTER> Pressure & flow rate visualization and recording> Programming & automation of complex sequences> Easy alternative instrument control through the provided C++, Python, MATLAB® andLabVIEW® libraries

www.elveflow.com contact@elveflow.com +33(0).184.163.807
Elveflow, an Elvesys brand / ©2019 Microfluidic Innovation Center. All rights reserved. Information is subject to change without notice

39 | 57[GO TO SUMMARY]PRODUCTS / ACCESSORIESACCESSORIESELVEFLOW ACCESSORIESELVEFLOW.COM/MICROFLUIDIC-PRODUCTS/MICROFLUIDICS-ACCESSORIES/MICROFLUIDIC ACCESSORIESYou can contact us anytime to order Elveflow
Accessories or request tech support.
The Elveflow accessories team is always
ready to make your experience fast andeasy. Alternatively, you can browse theElveflow Accessories product line on Darwin
Microfluidics and order online. Darwin
Microfluidics is our official online reseller.
Check it out!

MICROFLUIDIC RESERVOIRSBUBBLE REMOVERRESERVOIR XXS ON CHIP
4 TUBES HOLDERPRESSURIZED AIR SOURCEVACUUM GENERATORKIT FITTINGS STARTER PACK LUERKIT FITTINGS STARTER PACK PUSH IN
MANIFOLD 9 PORTS
PTFE TUBING 1/16" OD X 1/32" ID, 50M
REMOTE FLOW CONTROLPRESSURE SOURCEVACUUM SOURCENEW AND
IMPROVED PEEKBUBBLE TRAP

AUTOCLAVABLE & LEAK-RESISTANT
EASILY REPLACEABLE MEMBRANE

This improved version of Elveflow's bubble
trap is now autoclavable, thanks to the use of
PEEK (Polyetheretherketone). Three internal
volume versions are available: 23 µL (S), 95 µL(M), 362 µL (L).

www.elveflow.com contact@elveflow.com +33(0).184.163.807
Elveflow, an Elvesys brand / ©2019 Microfluidic Innovation Center. All rights reserved. Information is subject to change without notice

40 | 57[GO TO SUMMARY]RESERVOIRS TECHNICAL SPECIFICATIONSRESERVOIRSRESERVOIRS

Volume2 ports

4 ports

XXS

800 µLNA

NA

XS

1.5 - 2 mLavailable

not available

S

15 mL

available

available

M

50 mL

available

availableL

100 mLavailable

available

HP

150 mLavailable

not available

Non-contractual information, may be changed without notice.

RESERVOIRS SPECIFICATIONS DEDICATED TO THE OB1 PRESSURE CONTROLLERPRESSURIZEDTANK VERSION

OB1 PRESSURE CHANNEL RANGES
0 to 200 mbar
(0 to 2.9 psi)XXS

0 to 2,000 mbar

0 to 8,000 mbar

-900 to 1,000 mbar

-900 to 6,000 mbar

(0 to 29 psi)

(0 to 116 psi)(-13 to 14.5 psi)(-13 to 87 psi)

*

*

*

*

XS
S
M
L

**

**

HP

*not tested in these conditions** The reservoir passed the pressure resistance tests in these conditions; nevertheless, Elveflow
doesn’t recommend using it as they are sensitive to mechanical damagewww.elveflow.com contact@elveflow.com +33(0).184.163.807
Elveflow, an Elvesys brand / ©2019 Microfluidic Innovation Center. All rights reserved. Information is subject to change without notice

41 | 57[GO TO SUMMARY]PRODUCTS / ACCESSORIESEPSPRESSURE SOURCE
ELVEFLOW.COM/MICROFLUIDIC-PRODUCTS/MICROFLUIDICS-ACCESSORIES/LABORATORY-PRESSURE-SOURCE/

A COMPACT AND
LIGHT PRESSURE
SOURCEAn oil-free pressure source to ease theintegration in a laboratory environment thanks to
its small footprint and integrated tank.

PORTABLE
EASY-TO-USE

UNIQUE PERFORMANCES> Positive pressure 2 bar> Low noise level <53 dB> Small footprint 2kg

APPLICATIONS> This pressurized air source is ideal to supply
compressed air to a pressure regulator such as
the OB1.
> The steady pressure over 2000 mbar makes
it the perfect complementary pressure supply
for up to 2 channels 2 bar or 200 mbar OB1
pressure regulators.

www.elveflow.com contact@elveflow.com +33(0).184.163.807
Elveflow, an Elvesys brand / ©2019 Microfluidic Innovation Center. All rights reserved. Information is subject to change without notice

42 | 57[GO TO SUMMARY]OTHER PRESSURE GENERATOR: PRESSURIZED AIR SOURCE (KCP-230/120)

A CLEAN PRESSURIZEDAIR SOURCE
This lubricated air compressor is a
powerful alternative to laboratory gas
line supplies. The in-built 5 µm oil filter
prevents microdroplets from entering
into the instruments. In addition, anticorrosion treatments of the receiver andlong-life synthetic oil utilization makes
this pressurized air source the mostrobust companion for pressure-driven
control in laboratories.
ELVEFLOW.COM/MICROFLUIDIC-PRODUCTS/MICROFLUIDICS-ACCESSORIES/AIR-PRESSURE-GENERATOR/TECHNICAL SPECIFICATIONS COMPARISON
KCP-230 / KCP-120

PRESSURE SOURCE (EPS)

8 bar (120 psi)

3 bar (44 psi)

Air flow rate (at operatingpressure)

11 L/min

1.5 L/min (at 2 bar)

Noise level<35 dB<53 dB

38.4 x 33.3 x 34.2

16.1 x 19.4 x 19.5

18 Kg

2 Kg

Max pressure

Performances

KCP & EPS

Dimensions (without
connectors, cm)
WeightPneumatic connection

6mm push-in

Mechanical specifications

Electrical specifications

Internal receiver volume

4L

350 mLOperating temperature-

5-40 °C

Operating humidity-

Up to 80%

Input voltage range

-

24 V

AC supply frequency

50-60 HzPower supply voltage

100-240 VAC

Max current consumption

0.9 A

1.5 A (typical: 0.8 A)

Max power consumption-

36 W
Non-contractual information, may be changed without notice.

www.elveflow.com contact@elveflow.com +33(0).184.163.807
Elveflow, an Elvesys brand / ©2019 Microfluidic Innovation Center. All rights reserved. Information is subject to change without notice

43 | 57[GO TO SUMMARY]PRODUCTS / ACCESSORIESEVSVACUUM SOURCE
ELVEFLOW.COM/MICROFLUIDIC-PRODUCTS/MICROFLUIDICS-ACCESSORIES/NOISELESS-VACUUM-SOURCE/

A COMPACT AND
LIGHT VACUUM
SOURCEAn oil-free vacuum source to ease theintegration in a laboratory environment thanks to
its small footprint and integrated tank.

PLUG&PLAY
SMALL FOOTPRINTUNIQUE PERFORMANCES> Negative pressure -850 mbar
> Low noise level <51 dB> Small footprint 1.4 Kg

APPLICATIONS> This pressurized air source is ideal to supply
vacuum to a pressure regulator such as the OB1.
> The steady pressure of 2000 mbar makes it theperfect completementary vacuum supply for-900/1000 and -900/6000 mbar OB1 pressure
regulators.

www.elveflow.com contact@elveflow.com +33(0).184.163.807
Elveflow, an Elvesys brand / ©2019 Microfluidic Innovation Center. All rights reserved. Information is subject to change without notice

44 | 57[GO TO SUMMARY]OTHER VACUUM SOURCE: VACUUM GENERATOR (KVP-230)

A HIGH EFFICIENCYVACUUM PUMPThis high accuracy microfluidic
vacuum source generates negative
pressure for microfluidic flow control
without installation/connection of any
instrument. The anticorrosive coatingof the receiver ensures a long lifespanof the instruments.
ELVEFLOW.COM/MICROFLUIDIC-PRODUCTS/MICROFLUIDICS-ACCESSORIES/VACUUM-GENERATOR/TECHNICAL SPECIFICATIONS COMPARISON

KVP & EVSKVP-230 / KVP-110

VACUUM SOURCE (EVS)

Vacuum pressure (relative)-980 mbar (-15 psi)

-850 mbar (-13 psi)

Vacuum pressure (absolute)

20 mbar (0.1 psi)

150 mbar (2.3 psi)

Pumping speed

18 L/min

8 L/min at 0 bar

Noise level<42 dB<53 dB

30 x 17 x 24

14 x 18 x 14

3 Kg

1.4 Kg

Performances

Dimensions (without
connectors, cm)
WeightPneumatic connection

6mm push-in

Mechanical specifications

Electrical specifications

Internal receiver volume-

250 mLOperating temperature-

5-40 °C

Operating humidity-

Up to 80%

Input voltage range

-

24 V

AC supply frequency-

50-60 HzPower supply voltage

100-240 vac

Max current consumption-

1.5 A (typical: 0.8 A)

Max power consumption

140 W

36 W
Non-contractual information, may be changed without notice.

www.elveflow.com contact@elveflow.com +33(0).184.163.807
Elveflow, an Elvesys brand / ©2019 Microfluidic Innovation Center. All rights reserved. Information is subject to change without notice

45 | 57[GO TO SUMMARY]PRODUCTS

MICROFABRICATIONSTATIONS

PRODUCTS / MICROFABRICATIONSTATION

SU-8 MOLD STATIONELVEFLOW.COM/MICROFLUIDICS-APPLICATION-PACKS/MICROFABRICATION-STATIONS/SOFT-LITHOGRAPHY-SU8-PHOTOLITHOGRAPHY-STATION-MICROFABRICATION-TOOL/

A COMPLETE STATION TO
FABRICATE YOUR
SU-8 MOLDHIGH RESOLUTION WITHOUT CLEANROOMACCESSIBLE WITHOUT EXPERIENCE
FLEXIBLE AND UPGRADABLE PLATFORM
The benchtop SU-8 photolithography station includes
everything you need to make high-resolution master molds
in a reproducible manner.
Whether you are an experienced user or a beginner, ourstation provides robust and tabletop equipment to allow
you to fabricate your mold & chip independently after only
a week of training with one of our experts.

INCLUDED IN THE STATION> High-quality and robust spin-coater> Programmable hot plate for photoresist baking> High-collimated UV lamp with LEDs
> All the accessories and chemicals needed todevelop a quality process> One week installation and training
Each pack can be adapted to your laboratory and technical requirements.

CUSTOMIZE YOUR STATION
We offer a wide range of adaptable andupgradable alternatives to obtain a super-fastprocess with mid-resolution or to produce
multilayer devices with a very high-performance
direct laser process.

We ensure a clean installation of thestation in your lab and will train yourteam to fabricate your microfluidic
chips straight away.

Talk to our experts and find the right offer foryour experimental needs and lab infrastructure.
www.elveflow.com contact@elveflow.com +33(0).184.163.807
Elveflow, an Elvesys brand / ©2019 Microfluidic Innovation Center. All rights reserved. Information is subject to change without notice

47 | 57[GO TO SUMMARY]PRODUCTS / MICROFABRICATIONSTATIONPDMS CHIPS STATIONELVEFLOW.COM/MICROFLUIDICS-APPLICATION-PACKS/MICROFABRICATION-STATIONS/PDMS-STATION-SOFT-LITHOGRAPHY-MICROFABRICATION-TOOLS/ALL YOU NEED TO
PRODUCE YOURPDMS CHIPS

ALL-IN-ONE PLATFORM
REPRODUCIBLE PROCESSFAST FABRICATION PROCESSOur PDMS molding station comprises all the equipment
needed to replicate PDMS chips from premade molds in an
optimized manner.
Our plug & play system, detailed tutorials, and technicalsupport will make you skilled in the softlithography process
so you can manufacture high-quality PDMS chips.

INCLUDED IN THE STATION> Fitted desiccator to prepare your PDMS mix> Oven and soundwave bath for clean chips
generation> Robust Air plasma for strong bonding> Fitted pump and pressure controller for an easy
and reproducible process
Each pack can be adapted to your laboratory andtechnical requirements.

> All the accessories and chemicals needed todevelop a quality process

CUSTOMIZE YOUR STATION
Our offers are versatile and customizable. We cansuggest options to fabricate more complex stacks(with PDMS membranes, for example) or ways toreduce the station footprint.

We provide detailed tutorials andtechnical support for you to fabricate
your microfluidic chips straight away.

Talk to our experts and find the right offer foryour experimental needs and lab infrastructure.

www.elveflow.com contact@elveflow.com +33(0).184.163.807
Elveflow, an Elvesys brand / ©2019 Microfluidic Innovation Center. All rights reserved. Information is subject to change without notice

48 | 57[GO TO SUMMARY]PRODUCTSAPPLICATIONPACKS

PRODUCTS / APPLICATION PACKSMICROFLUIDICS PACKMICROFLUIDIC STARTER
ELVEFLOW.COM/MICROFLUIDICS-APPLICATION-PACKS/MICROFLUIDICS-PACKS/STARTER-PACK/ALL YOU NEEDTO DISCOVER
MICROFLUIDICSGET STARTED NOWGREAT FOR MANY APPLICATIONSEASY UPGRADE
Elveflow’s Starter Pack is customized according to
your needs so that you will benefit from highly-accuratepressure-driven control in your microfluidic applications.
The powerful ESI software controls your entire setup,
allowing you to fully control pressure, monitor yourexperiment, or try advanced functions such as fullautomation and running scripts.

CONTENT OF THE PACK
Microfluidics can be applied to several
different applications. Thus, the Starter
Pack is adjusted to suit your specificexperimental needs.

Generally included:> 4 x Pressure channels> 4 x 50 mL Reservoirs> All necessary accessories: tubing, connectors, etc…

Additional Options:> Flow rate sensors
Flow controller
OB1 MK4> Microfluidic chips

Flowsensor> Microscope and camera

Microfluidic chip

Talk to our experts and build
the pack perfectly fitted toyour needs.

Reservoirs

www.elveflow.com contact@elveflow.com +33(0).184.163.807
Elveflow, an Elvesys brand / ©2019 Microfluidic Innovation Center. All rights reserved. Information is subject to change without notice

50 | 57[GO TO SUMMARY]PRODUCTS / APPLICATION PACKSMICROFLUIDICS PACKDROPLET GENERATIONELVEFLOW.COM/MICROFLUIDICS-APPLICATION-PACKS/MICROFLUIDICS-PACKS/STARTER-PACK/TURNKEY SYSTEM TO
EASILY GENERATEDROPLETSREPRODUCIBLE & EASY GENERATIONPERFECT FOR MANY APPLICATIONSPLUG & PLAY
This Dropet Pack is based on the premium Elveflow
instrument range and our best-seller - the OB1 flow
controller.
Thanks to the OB1's high performance and accuracy, youwill be able to generate highly monodisperse droplets(CV<3%) ranging from 10 to 80 µm diameter (and moreusing alternative microchips).

CONTENT OF THE PACKTwo versions of this pack are available:

Generally included:> the small version (droplets ranging from 10 to 40 µm
diameter)> 2 x Pressure channels> the large version (droplets ranging from 50 to 80 µm
diameter).

> 2 x Microchips> 2 x Flow rate sensors> 2 x Flow resistors> A complete user guide> All necessary accessories:
tubing, reservoirs, etc…

INTERESTED IN DROPLET?
Talk to our experts and build
the pack perfectly fitted to yourneeds.

www.elveflow.com contact@elveflow.com +33(0).184.163.807
Elveflow, an Elvesys brand / ©2019 Microfluidic Innovation Center. All rights reserved. Information is subject to change without notice

51 | 57[GO TO SUMMARY]PRODUCTS / APPLICATION PACKSMICROFLUIDICS PACKSEQUENTIAL INJECTION
ELVEFLOW.COM/MICROFLUIDICS-APPLICATION-PACKS/MICROFLUIDICS-PACKS/SEQUENTIAL-FLUID-INJECTION-PACKQUICKLY SWAP BETWEENUP TO 12 FLUIDS(GAS OR LIQUIDS)

HIGH STABILITY AND PRECISIONWORKFLOW AUTOMATIONHIGH VERSATILITYThe Sequential Injection Pack includes all the necessary
elements to sequentially inject up to 12 (or more) solutions
in a fully automated fashion using our computer-controlled
12 to 1 MUX Distribution bidirectional valve.
An extensive flow rate range (from 7 nL/min to 30+ mL/min) and volumes (100 µL to up to several Liters) areaccessible with this system.

CONTENT OF THE PACKThis pack can be adapted for more
complex and advanced experiments
such as using 20 or more solutions,removing bubbles, integration intolarger systems or testing multiple
chip/devices simultaneously.

Generally included:> 4 x Pressure channels> 1 x Mux Distribution rotary valve> 1 x Flow sensor> 1 x Pressure splitter manifold> All necessary accessories: reservoirs, tubing, etc…

INTERESTED IN LIQUID INJECTION?
This is only a suggestion of what could
be included in this pack

Talk to our experts and build
the pack perfectly fitted to yourneeds.

www.elveflow.com contact@elveflow.com +33(0).184.163.807
Elveflow, an Elvesys brand / ©2019 Microfluidic Innovation Center. All rights reserved. Information is subject to change without notice

52 | 57[GO TO SUMMARY]PRODUCTS / APPLICATION PACKSMICROFLUIDICS PACK

LIPID NANOPARTICLE SYNTHESISELVEFLOW.COM/MICROFLUIDICS-APPLICATION-PACKS/MICROFLUIDICS-PACKS/STARTER-PACK/HIGHLYREPRODUCIBLE
NANOPARTICLESVERSATILE NANOPARTICLE SYNTHESISPERFECT FOR MANY APPLICATIONSPLUG & PLAY
This Lipid Nanoparticle Pack is designed for researchers
without prior microfluidics experience or lipid nanoparticle
generation aiming to easily synthesize lipid nanoparticles(LNP).
Lipid nanoparticles (LNP), solid lipid nanoparticles (SLN),
and nanoliposomes produced by microfluidics are used toencapsulate all types of drugs or organic compounds.

CONTENT OF THE PACKThe kit comes in two versions to perfectly fit yourrequirements.

It includes:> Herringbone Mixer> 2 x Flow rate sensors> Flow Focusing> 2 x Pressure channels> 1 x Microchips> 2 x Flow resistors> A complete user guide> All necessary accessories:
tubing, reservoirs, etc…

INTERESTED IN NANOPARTICLE?
Talk to our experts and build
the pack perfectly fitted to yourneeds.

www.elveflow.com contact@elveflow.com +33(0).184.163.807
Elveflow, an Elvesys brand / ©2019 Microfluidic Innovation Center. All rights reserved. Information is subject to change without notice

53 | 57[GO TO SUMMARY]PRODUCTS / APPLICATION PACKSBIOLOGY PACKRECIRCULATIONELVEFLOW.COM/MICROFLUIDICS-APPLICATION-PACKS/BIOLOGY-PACKS/ONE-WAY-RECIRCULATION/

AUTOMATE YOUR
EXPERIMENTS FOR
SEVERAL DAYSUNIDIRECTIONAL LIQUID FLOWNO MORE MEDIA DEPLETIONUNIFORM SHEAR STRESSThe Recirculation Pack uses two pressure channels
to flow medium through your microfluidic device
unidirectionally and continuously.
The recirculation valve allows switching between two
reservoirs, ensuring the medium always flows from themost filled one. The injection loop consists of a network of
inputs/outputs that can connect in two configurations.

CONTENT OF THE PACK
Additional features, such as medium
switch, on-off sample injection, etc. arealso possible by adding other Elveflow
equipment to your Recirculation Pack.

Position A
Recirculation valve

Generally included:> 2 x Pressure channels> 2 x Reservoirs> 1 x Recirculation valve> All necessary
accessories

Microfluidicchip

MUX Recirculation

Position B
Recirculation valve
MUX Recirculation

Flow controller

Flow controller

OB1

OB1

www.elveflow.com contact@elveflow.com +33(0).184.163.807
Elveflow, an Elvesys brand / ©2019 Microfluidic Innovation Center. All rights reserved. Information is subject to change without notice

Microfluidic
chip

54 | 57[GO TO SUMMARY]PRODUCTS / APPLICATION PACKSBIOLOGY PACKORGAN-ON-A-CHIP
ELVEFLOW.COM/MICROFLUIDICS-APPLICATION-PACKS/BIOLOGY-PACKS/ORGAN-ON-A-CHIP-PACK/FLOW MEDIUM THROUGHONE OR SEVERALPARALLEL CHIPSMIMIC PHYSIOLOGICAL CONDITIONSREPRODUCIBLE AND SCALABLEEFFORTLESS LONG-TERM EXPERIMENTS
The Organ-On-Chip Pack allows you to perfuse media
through a chip containing living cells to mimic in vivo
physiology better.
The setup includes one flow controller that allows
accurate control of multiple parameters, such as chemical
concentration gradient, fluid shear stress, cell patterning,tissue-tissue interface, organ-organ interaction, andphysiological responses.

CONTENT OF THE PACK
Several chip designs are available for organ-on-chip
experiments, depending on the type of organ you want
to mimic and your experimental protocol.

Generally included:> 2 x Pressure channels> 2 x Flow rate sensors> 2 x Reservoirs> All necessary accessories:
tubing, connectors, etc...

Flow sensor 2
MFS
Microfluidic chip

Reservoir 2
medium> Microfluidic chip advices> MUX Distribution

Flow sensor 1
MFS

Reservoir 1
mediumAdditional Options:

INTERESTED IN ORGAN-ON-CHIP?

Feedback
loop

Talk to our experts and build
the pack perfectly fitted to yourneeds.
Pressure controller
OB1 2 channels

www.elveflow.com contact@elveflow.com +33(0).184.163.807
Elveflow, an Elvesys brand / ©2019 Microfluidic Innovation Center. All rights reserved. Information is subject to change without notice

55 | 57[GO TO SUMMARY]PRODUCTS / APPLICATION PACKSBIOLOGY PACKLIVE CELL PERFUSION
ELVEFLOW.COM/MICROFLUIDICS-APPLICATION-PACKS/BIOLOGY-PACKS/PERFUSION-FOR-CELLS-AND-BIOLOGY/

LIQUID HANDLINGFOR CELL-BASEDEXPERIMENTS

MULTIPLE MEDIA PERFUSIONCONTROLLED SHEAR STRESSWORKFLOWS AUTOMATIONThe Cell & Biology Pack uses one pressure channel to flow
multiple solutions into the microfluidic chip. It is ideal forshear stress assays and imaging cell response to various
media or drugs.
You will be able to design flow injection sequences andcreate complex patterns, such as oscillating flow to mimic
physiological conditions.

CONTENT OF THE PACKThis pack is ideal for complex and advanced Cell & Biology
experiments and can be adapted to your needs. For
example, you may choose a suitable microfluidic chip, use
more than 20 solutions, remove bubbles, or have multiple
chip/inlet perfusion.

Generally included:> 1 x Pressure channel> 1 x Flow rate sensor> 1 x MUX Distribution valve> 3 x Reservoirs> 1 x Bubble remover

OB1

Flow controller
USB
MFS

Flow sensor

Manifold> All necessary accessories:
tubing, connectors, etc...
Additional Options:> Microfluidic chips advices> Microscope and camera

Reservoir holder rack

MUX Distrib

Distribution valve

Setup

Microﬂuidic chipwww.elveflow.com contact@elveflow.com +33(0).184.163.807
Elveflow, an Elvesys brand / ©2019 Microfluidic Innovation Center. All rights reserved. Information is subject to change without notice

INTERESTED IN PERFUSION?
Feel free to contact our experts.

56 | 57[GO TO SUMMARY]PLUG & PLAY MICROFLUIDICS

GENERAL INFORMATION
contact@elveflow.com+33(0).184.163.807

www.elveflow.com
ELVESYS – Microfluidics innovation center

ART DIRECTOR JULIEN RIDOUARD

172 rue de Charonne
75011 Paris, FRANCEMICROFLUIDIC POETRY,
an uncommon, conceptual and sensitive vision of the
microfluidic field, on the blurring border between art & science.
https://www.elveflow.com/microfluidic-tutorials/microfluidic-reviews-and-tutorials/microfluidic-poetry-unique-imaginative-sensitive-vision-microfluidics-field/