Operant

Control and Conditioning
for Rodents

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ABET II SOFTWARE FOR OPERANT CONTROLStandard		

Touch			VideoTouch

Model 89501		

Model 89505		

Model 89509

ABET II offers a system that can be user customized
and programmed with no programming experience.
Every effort has been made to make this easy touse for those with minimal operant conditioning
experience, yet powerful enough to run complex
schedules for the experimental analysis of behavior.
If you can conceptualize your experiment in a flow chartor a spreadsheet, you can create the conditions andactions needed for virtually any scheduled task.

What is ABET II?
Environment Designer• Easily assign labels to inputs and outputs connected to the computer• Add or duplicate environments as needed• Full suite of environment testing and management tools

Schedule Designer• A single workspace with all the tools needed to program your environment. Simply click on the appropriate tool to add,
edit, or delete device aliases, variables (timers, counters, constants), lists, and conditions• Label and define simple variables, timers, counters, constants and lists without restrictions or limitations• Draw from a list in truly random order, random without repeat, random without replacement, or sequential order• Define a simple or complex condition with single or multiple actions• Never write a single line of program code. ABET II will print all schedule details in a well organized spreadsheet like format
that is color-coded to make it easy for anyone to follow each logical step. Schedules can be versioned and locked to preventany data corruption once an experiment is started

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Execution Manager
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Load single or multiple environments with same or different schedules in one step
Add session variables as needed for notes, animal identification, weight, dose or treatment, and other information
Adjust variable settings globally or individually from the keyboard or an experiment file
Activate a real-time debugger when needed to follow and save each performance step of a schedule while it is being tested
Enjoy the security of the most comprehensive results database of any system

Data Viewer
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Load one or multiple sessions for viewing
Select your data source, date range or multiple selection criteria to isolate only the sessions of interest
Display Session information, raw data, event totals, reduced data, IRT’s and Bins
Copy or export selected data or entire data views to Excel or a statistical package of your choice
Recall locked schedules from the encoded database for future replication if ever needed

Analysis Set Designer
Perform unlimited user defined analysis of measures/paths (latencies), bouts, or counts.  Because ABET II records every detail ofa session with millisecond precision, data elements need not be pre-programmed as with other systems.

Graphical Cumulative Record
Design a graphical cumulative record with numerous tools to define the chart size, step traces, pips, and  events.

Virtual Interface
Install ABET II on your laptop, office computer or any computer not connected
to hardware and use the Virtual Interface as a duplicate of the environmentthat you have in your lab. Write/program, review, and test schedules or analyze
lab data while disconnected from the lab hardware or offline. Schedules anddata are easily passed to and from your lab via a network connection or any
removable media.

Virtual Touch Interface
In addtion to the original Virtual Interface, ABET II Touch and ABET II
VideoTouch also include a Virtual Touch Interface system where graphic andtouch-based schedules can be generated and emulated via a computer’s mouse.

Contact us for a demonstration!

Whisker® Multimedia
ABET II Touch and ABET II VideoTouch rely on the Whisker operating system
to control the advanced graphical output on multiple screens, and touch screen
input from multiple chambers when running the Bussey-Saksida Rodent Test
Chambers. This is the same underlying platform used in primate and human
CANTAB touch screen stations for translational cognitive testing. Whisker has
been cited in over 142 publications across more than 34 journals.

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ABET 2G HARDWARE FOR OPERANT CONTROLABET 2G PCI Interface Card and Cable
Model 81504
A single computer PCI circuit board and 100 conductor ribbon cable now connect directly to the
ABET 2G Starter Interface to support 1 – 12 test chambers.  The driver box and additional cables
used in older systems have now been eliminated.

ABET 2G Starter Interface
Model 81501
This base unit may be used to support two test stations with 8 Inputs and 15 Outputs each,or a single test station with 16 Inputs and 30 Outputs. Each half is independently fused, with
software controlled safety relays to shut off the 28 V DC when not actively controlled. Output
drivers are more robust with higher current limits than previous units. This unit features
latched inputs to filter and de-bounce animal responses.  Order Model 81501-NL with nonlatched inputs if required.

ABET 2G Expansion Interface
Model 81502
This unit stacks on top of the 81501 to support additional chambers. There are no cards toinstall or cables to connect between modules. Standard DB-25 cables connect between theinterface and the chamber I/O connection block.

Mini I/O Connection Block
Model 81409
This functional connection block features connections for 8 Inputs and 15 Outputs throughconvenient multilevel, screw clamp terminals. Five modular connections parallel the 15 Outputs
for those chamber components that provide intensity or other programmable control from three
sequential output lines.  The Model 81409 Connection Block mounts to the chamber base andconnects to the interface with a standard DB-25 Connector.

Full I/O Connection Block (for ABET 2G)
Model 81508
This unit is functionally identical to the model 81409 above except it is designed to provide
16 Inputs and 30 Outputs to a single chamber. An edge connector is provided for easy
connect to Plexon Data Acquisition systems as well as other similar products for time stamp
synchronization of chamber events with the recorded signal.

30 Volt DC Power Supply
Model 83619
Multiple power supplies may be combined to increase the current capacity for multiple chamber operation from a single
interface package. The number of supplies needed depends on the current needs of the chamber components and soundattenuating cubicle when present. Short circuit protection is provided by internal current fold-back circuitry.
Line Voltage: 110 - 115 V AC @ 60 Hz (also available 220 – 230V AC @ 50 Hz)

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RAT MODULAR CHAMBERS & ACCESSORIESModular Chamber			Tall Modular Chamber

Model 80004

Model 80016

Model 80004NS		

Model 80016NS

The operant conditioning test chambers boast features notfound in other chambers, yet are fully compatible with all 3”
wide modular panels available from other manufacturers. A
shockable stainless steel grid rod floor comes standard withthese units.  Models 80004NS/80016NS are identical to
Models 80004/80016 in all respects except the shockablegrid floor has been replaced by a less expensive perforated
stainless steel non-shock floor.

Chamber Features• Easy to remove top with just four thumbscrews• Large Stainless Steel waste pan slides on smooth rails toeliminate the gap between the pan and modular panels
found in other systems

Model 80004
with Accessories• Channel Supports that can not twist for no-bind module removal• A heavy-duty latch that is easy to close and cannot be accidentally opened• A full line of modules are available including nose pokes, simple tone, tone with intensity control, variable frequency tone,
stimulus light with or without intensity level, standard or extra thick fixed or retractable response levers, pellet or liquid
reward, simple receptacle, or receptacle with door, head entry detection, and house light

80004 Chamber Dimensions

80016 Chamber Dimensions

Overall• 23.5” L  x  13.4” D  x  10.5” H• 59.7 x 34.0 x 26.7 cm

Overall• 23.5” L  x  13.4” D  x 14.6” H• 59.7 x 34.0 x 26.35 cm

Animal Workspace• 12.0” L x 10.2” D x 7.9” H• 30.5 x 25.9 x 20.1 cm

Animal Workspace• 12.0” L  x  10.2” D  x  12.0” H• 30.5 x 25.9 x 30.5 cm

Grid Rod Floor• 0.188” (4.775mm) rods on 0.610” (15.494 mm)
centers

Grid Rod Floor• 0.188” (4.775mm) rods on 0.610” (15.494 mm)
centers

Modular Rat Test Chamber with Touch Screen
Model 80004TS

Model 80016TS

This unit is the same as the 80004/80016 above except the inside rear channels have been removed and a touch screen has
been added to support a wide range of additional testing capabilities. This chamber requires additional interface, software, andreward components. Ready to run Bussey-Saksida Touch Chambers are also available to run Standard Applications. Pleasecontact Lafayette Instrument Company for more information.

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5

Press Bar
Model 80110M
The heavy duty (0.032” thick) stainless steel construction of this lever ensures long lasting reliable
operation. A micro switch is used to provide a Normally Open (NO) and Normally Closed (NC) contact thatsenses lever activation. The force required to move the bar is factory calibrated to be less than 10 gm and isfield adjustable via counterbalance washers located on the back.  This is preferred over spring systems thatcan change over time or hang up on the moving lever.  Movement required to activate the lever switch is 3
mm. (Normally Closed (NC) contact available on request)

Thick Profile Response Lever
Model 80112M
This is a high quality lever designed in the image of the Ralph Gerbrands and BRS levers that are nolonger available. It features a solid aluminum bar that requires a nominal 25g of force with adjustable
travel, adjustable trigger point and adjustable force. Both NO and NC contacts are provided to monitor
lever press and lever release.  The response paddle measures 1.5” (3.8 cm) wide x 0.5” (1.27 cm) thickwith a protrusion of 0.625” (1.5875 cm).

Retractable Response Lever
Model CI4460-M
This deluxe retractable response lever is designed for use in the Modular Test Chambers and comes mounted on a 4U panel (not shown).  Features include a thick stainless steel lever with reliable transport, friction
free pivot, I/R sensor, adjustable travel (0.125” (0.3175 cm) nominal) and adjustable force (10-35g).  Both
Normal and Inverted response lines are provided along with a position status line (inserted or retracted).
The response paddle measures 1.9” (4.8 cm) wide x 0.63” (1.6 cm) thick with a protrusion of 0.787” (2.0 cm).

Nose Poke w/ Tri-Color Light
Models 80116TRM and 80117RM
These Nose Poke modules feature a reliable I/R sensor and tricolor light with colorand intensity control as well as multiple mode control. Three output control lines are
required at 24-29 V DC.  The Model 80117RM  adds a liquid delivery tube, conicalaperture, and large plastic surround specially designed for animals wearing head stages.
80117RM

80116TRM

White Stimulus Light
Models 80225M and 80226M
This 1” stimulus light has been introduced to replace the 80221M.  It uses the same bulb as the 80221M
for identical intensities.  The lens is recessed behind the modular panel and is perfectly flat to minimize
damage from chewing.  The lens is easy and inexpensive to replace.  

Tone Generator
Model 81415
This Tone Generator is a digitally controlled frequency generator that can be used for auditory
stimulus in animal behavior studies. It produces seven frequencies ranging from 1 to 16 kilohertz
and offers convenient modular cable connection to either of the ABET I/O modules (Models 81408
or 81409).  

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6White Noise Module			

Clicker Module

Model 80136M				

Model 80137M

A number of components are available for auditory stimulation. Just two are listed above. Contact Lafayette Instrument
Company with specific needs to obtain additional information on components not found in this brochure.

45mg Pellet Dispenser
Model 80209M
This 45mg Pellet Dispenser uses the latest design features to provide consistent and reliable pellet
delivery. It can easily be converted to other pellet sizes and made even more reliable with an optionalpellet drop detector.  The dispenser is supplied with a selector disk suitable for 45mg pellets asstandard, alternative disks suitable for 14mg or 20mg pellets are available.  Order replacement disks
or optional pellet detector separately.

Standard Pellet TroughModel 80210M
This basic pellet only reward module with receptacle cup is supplied on a convenient 4U modular panel.  
The front opening measures 2.15” x 2.15” (5.5 x 5.5 cm).

Pellet Trough w/ Head Entry and Door
Model 80210M-R
This deluxe pellet receptacle includes a clear door with door sensor, receptacle light, and second I/Rsensor for head detection when the door is not used.

Liquid/Pellet Trough w/ Head Entry and Door
Model 80210LM-R
This deluxe receptacle is suitable for both pellet and liquid reward.  It includes a clear door with door sensor,
receptacle light, and second I/R sensor for head detection when the door is not used. The bottom cup ismilled aluminum and features two liquid delivery tubes with removable stylets that can be flushed andcleaned outside the receptacle.

Infusion Pump for Drug Self Administration or Liquid Reward
Model 80203
This 3.33 RPM Constant Speed Pump will accept a number of syringe sizes to meet a range of flow
rates from approximately 2uL/second to 0.07mL/second.  A timed pulse on the control line is used
for the precise amount desired for each delivery. This unit includes an end of syringe limit switch andsafety time limit to prevent overdose in drug delivery applications. Model 80204 Peristaltic Pump
(with flow rate of 0.025 ml/sec) is recommended for liquid reward only.

Ambulatory Monitor for 80004 Modular Test Chamber
Model 80004AM
A single strip at the back of the chamber and on the door hold three I/R photo beams strategicallylocated at the rear, center and front of the chamber. They can be use for classical conditioning
procedures, procedures that require the animal to be in a certain location for a trial to start, or for
general ambulatory monitoring in the operant test chamber.

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7MOUSE MODULAR CHAMBERS & ACCESSORIESModel 80015		

Model 80015NS

These carefully designed operant conditioning test
chambers feature a reduced floor area to facilitate training
mice on operant tasks.  Units include many of the samefeatures found in the standard rat modular test chambers.
You get the choice of a chamber with a perforated stainlesssteel non-shock floor (Model 80015NS), or a stainless steel
grid rod floor (Model 80015),  a stainless steel waste pan,and full filler panels are included with each chamber.

Chamber Features• Easily removable top with just four thumbscrews• Large Stainless Steel waste pan slides on smooth rails toeliminate the gap between the pan and modular panels
found in other systems

Chamber Dimensions
Overall• 19.3” L   x  10.6” D  x  10.5” H• 48.9 x 26.9 x 26.7 cm
Animal Workspace• 7.4” L   x  8.1” D  x  7.9” H• 18.8 x 20.6 x 20.1 cm
Floors• Model 80015NS perforated stainless steel nonshock floor 0.25” (6.35 mm) diameter holes
staggered rows 0.315” (8 mm) center to center• Model 80015 Grid Rod Floor 0.156” (3.962mm)
diameter stainless steel rods on 0.321” (8.15mm)
spacing center to center

Modular Mouse Test Chamberwith Touch Screen
Model 80015TS
This unit boasts many of the features of the 80015NS. The
inside rear channels have been removed and a touch screen
added to support a wide range of new testing capabilities.
The side walls have been tapered to help position the animal
for better viewing of the stimuli. This chamber requires
additional interface, software, and reward components.
Ready to run Bussey-Saksida Touch Chamber packages arealso available with standard validated applications. Pleasecontact Lafayette Instrument Company for additional
information on both.

Retractable Response Lever
Model CI4461-M
This deluxe retractable response lever is designed for use in the Mouse Modular Test Chambers andcomes mounted on a 4U panel.  Features include a thin stainless steel lever with reliable transport, friction
free pivot, I/R sensor, adjustable travel (0.08” (2.032 mm) nominal) and adjustable force (2 - 9 grams).  
Both Normal and Inverted response lines are provided along with a position status line (inserted or
retracted).  The response paddle measures 0.63” (16 mm) wide with a protrusion of 0.433” (11 mm).  This
unit operates on 24 - 28 V DC.  The operate line must be grounded to extend the lever.  The position reportprovides a GND sink when the lever is extended and is open when retracted.  The NO & NC “Contacts”
provide GND when activated.

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Standard Response Lever
Model 80120MM
This lever features a small stainless steel paddle mounted on a 2U aluminum modular panel.  The low
response force of less than 3g is adjustable.   The paddle dimensions are 0.632” (16 mm) wide x  0.04”(1.02 mm) thick with a protrusion of 0.3455” (8.77 mm).  Electrically, both NO & NC Contacts areprovided.

Mouse Nose Poke with Tri Color Stimulus
Model 80116TM14
This nose poke module feature a reliable I/R sensor and tricolor stimulus light with color andintensity control as well as multiple mode control. Three output control lines are required. Other
models are available on request.

White Stimulus Light
Model 80225M14

Model 80226M14

This 1” stimulus light is recessed behind the modular panel and is perfectly flat to minimize
damage from chewing. The lens is easy and inexpensive to replace should it ever be damaged.

Auditory Stimulus Components for Modular Mouse Test Chambers
A number of components are available similar to those described for the Rat Modular Test Chamber on previous pages. Contact
Lafayette Instrument Company with specific requirements to receive additional information.

Peristaltic Pump for Liquid Reward
Model 80204M
This Liquid Pump with electronic brake is designed for precise delivery of liquid reward when
operated from a short duration electrical pulse. This pump is supplied with a small length of 0.5 mm
bore tubing for a flow rate of approximately 0.025 ml/sec.  Contact Lafayette Instrument Company
for alternative flow rates and pumps.

20mg Pellet Dispenser with Stand
Model 80209-20
This dispenser mechanism is identical to the Model 80209M, as described with the Rat Modular
Test Chambers, except that it comes on a base mounted stand and features a delivery disk with
20 mg pellet dimensions.  This disk may be interchanged with a 14mg or 45mg disk (optional
disks sold separately) with no additional modification or adjustment.   Connections to thedispenser are made via the 5 way terminal block on the edge of the control printed circuit board.
An optional pellet drop detector is also available.

Mouse Reward Area for Modular Test Chamber
Model 80211RAXMM
A deluxe Liquid / Pellet Reward Area that includes a clear door with door sensor, receptacle light,
and second I/R sensor for head detection when the door is not used. The bottom cup is milled
aluminum and features two liquid delivery tubes with removable stylets that can be flushed andcleaned outside the receptacle.

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9SOUND ATTENUATING CUBICLESSound Cubicle - Double Door Peep
Model 83018DDPThis cubicle is one of several models constructed of expanded PVC
foam panels that resist moisture and many chemicals. All outside walls
are 0.75” (19 mm) thick. This Model features double doors with arubber seal to minimize air and light incursion and a covered peepholefor animal viewing. The left door is larger than the right so that animals
may be loaded by opening a single door. The door hinges allow 180
degrees of movement (twice that of other units) and can be quickly
released without tools to remove the doors when necessary. The
standard slide out tray makes this cubicle usable with both front and
top loading chambers. A 28 Volt DC ventilation fan and house light areincluded with each cubicle. Visit our web site or contact the Lafayette
Instrument Company offices for information on alternative designs
and sizes.

Sound Cubicle - Double Door Window
Model 83018DDW
This unit is identical to the above except the covered peep hole is replaced witha large red tinted double pane viewing window.

Single Door Sound Isolation Cubicle - Window
Model 83018SDW
These units feature a sound cubicle enclosure identical to the above except the double
hinged doors are replaced by a single fully removable door. Recommended where itis necessary but not practical to have the cubicle doors open for extended periods oftime.

Single Door Sound Isolation Cubicle - Peep
Model 83018SDP
This unit is identical to the model 83018SDW above with the same viewing peep hole shown on the Model 83018DDP.

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10ADDITIONAL CHAMBERS FOR RODENTS
The 5CSRT Task
Nose Poke Chambers and Touch Screen Chambers are Available for the 5CSRT task and othercognitive testing in both rats and mice.
The 5CSRT Task is a test of sustained and selective attention and reaction time, which has been wellcharacterized in the rat and mouse to show clinical validity in a variety of settings. Clinical models
showing impairment in this area include Alzheimer’s, Depression, Huntington’s, Schizophrenia, ADHD
and OCD.  The neural systems that have been implicated include Prefrontal cortex, basal forebrain,cholinergic (accuracy), serotonin (impulsivity), noradrenalin (distraction), and dopamine (motivation).
It is one of the oldest of operant based tests in mice designed to exploit molecular genetics methods inunraveling the genetic contribution to complex psychological and behavioral processes.
The standard application packages provided by Lafayette Instrument Company and Campden Instruments Ltd. include nine
separate schedules for the rat and eleven for the mouse to test the hardware, calibrate the reward (liquid only), train the animal,
and run basic and advanced forms of the 5CSRT Task. The individually written schedules run on ABET II Standard and are
written with multiple user set options and extensive data analysis and reporting.

The Bussey-Saksida Touch Screen Chamber
The Bussey-Saksida Touch Screen Chamber packages may be used to run the same 5CSRT Task
described above. Furthermore, they have bridged the gap in translational research from non-humanprimates to rats and mice.
Using virtually the same cognitive tests such as Visual Discrimination and Reversal, Paired Associates
Learning, Visuomotor Conditional Learning, Extinction, Trial-Unique Nonmatching to Location,
Location Discrimination, and Pavlovian Autoshaping, rats and mice can now be used in investigationsof several neural systems, models of several clinical impairments and drug discovery. Standard
applications are available for all the above tests using the unique ABET II Touch Software from
Lafayette Instrument Co. In addition to running standard applications, this software lets the user
create original schedules with all the stimulus-response features of the touch chamber. The user
friendly tools provided with ABET II Touch do not require you to be a programmer.
Not just another square sheet metal box, the Bussey-Saksida chamber has a unique trapezoidal wall shape to focus the animal’s
attention and is made from machined parts that simply slot together. The chamber can also be configured to a modular squarechamber with panels, levers, lights, and a range of other operators. Not just a touch screen, this is the ultimate modular chamber
for high throughput. For example, do Visual Discrimination and Reversal in the morning and Five Choice Serial Reaction Time
Task in the afternoon.

Drug Self Infusion/Administration Test Package
This package retains those features necessary for consistent and reliable animal testing with theaddition of features and improvements not found in any other system. It is fully compatible with all 3”
modules manufactured by Lafayette Instrument Company, as well as, those manufactured by others.
The standard chamber configuration includes two standard response levers, stimulus lights, and an
Infusion Pump is used to deliver drug rewards. Select from the standard stainless steel shock grid flooror an economical perforated stainless steel floor. Other configurations are available on request.

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Contact Us for a Quotation or More Information
Worldwide Office3700 Sagamore Pkwy N
Lafayette, IN 47904
USA
Phone:     (765) 423-1505
Fax:      (765) 423-4111
sales@lafayetteinstrument.com
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European Office
P.O. Box 8148
Loughborough,Leics. LE12 7XTEnglandTel:   +44 1509 814790
Fax:  +44 1509 817701
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www.campdeninstruments.com

Copyright © 2014-2017 Lafayette Instrument Company, Inc. All Rights Reserved.

10.18.17

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