小杉 健三（こすぎ けんぞう）

下記は 2023 年 5 月現在の情報です。
■略歴2012 年

慶應義塾大学医学部卒業

2012-14 年

総合病院国保旭中央病院 臨床研修医

2014-15 年

足利赤十字病院 脳神経外科

2015-16 年

慶應義塾大学 専修医（医学部 脳神経外科学教室）

2016-17 年

独立行政法人国立病院機構栃木医療センター 脳神経外科

2017-20 年

慶應義塾大学 助教（医学部 脳神経外科学教室）

2020-22 年

国立精神・神経医療県級センター病院 脳神経外科

2022-現在

慶應義塾大学 助教（医学部 脳神経外科学教室）■所属学会
日本脳神経外科学会
日本定位・機能神経外科学会
日本臨床神経生理学会
日本ニューロモデュレーション学会
日本てんかん学会
日本てんかん外科学会
日本神経内視鏡学会
日本小児神経学会■主な資格
日本脳神経外科学会専門医
機能的定位脳手術技術認定医
日本臨床神経生理学会専門医（脳波部門）
難病指定医
臨床研修指導医養成ワークショップ修了

■業績
1) Kosugi K, Takahashi S, Sasaki H, Tamura R, Ohara K, Yoshida K. A case of acute subdural
hematoma due to bleeding from metastatic chondrosarcoma of the skull. Surg Neurol Int.
2017;8:23.
2) Kosugi K, Saito K, Takahashi W, Tokuda Y, Tomita H. A Case of Therapy-Related Acute
Myeloid Leukemia Associated with Adjuvant Temozolomide Chemotherapy for Anaplastic
Astrocytoma. World Neurosurg. 2017;101:816.e11-816.e16.
3) Tamura R, Ohara K, Sasaki H, Morimoto Y, Kosugi K, Yoshida K, Toda M. Difference in
Immunosuppressive Cells Between Peritumoral Area and Tumor Core in Glioblastoma.
World Neurosurg. 2018;120:e601-e610.
4) Toda M, Kosugi K, Ozawa H, Ogawa K, Yoshida K. Surgical Treatment of Cavernous Sinus
Lesion in Patients with Nonfunctioning Pituitary Adenomas via the Endoscopic Endonasal
Approach. J Neurol Surg B Skull Base. 2018;79(Suppl 4):S311-S315.
5) Kosugi K, Tamura R, Mase T, Tamura H, Jinzaki M, Yoshida K, Toda M. Relationship between
pneumatization of lateral recess in the sphenoid sinus and removal of cavernous sinus
invasion in pituitary adenomas by endoscopic endonasal surgery. Surg Neurol Int.
2019;10:222.
6) Hirata S, Kobayashi M, Kamamoto D, Kosugi K, Yoshida K, Fujimaki T. Trigeminal Neuralgia
Due to Petrosal Bone Deformity. World Neurosurg. 2019;126:79-82.
7) Kanazawa T, Miwa T, Akiyama T, Ohara K, Kosugi K, Nishimoto M, Yoshida K. A Case ofAggressive Recurrent Intracranial Subdural Hematoma Associated with Angiosarcoma
Originating from the Skull. World Neurosurg. 2019;126:120-123.
8) Morimoto Y, Tamura R, Ohara K, Kosugi K, Oishi Y, Kuranari Y, Yoshida K, Toda M.
Prognostic significance of VEGF receptors expression on the tumor cells in skull basechordoma. J Neurooncol. 2019;144(1):65-77.
9) Sato M, Tamura R, Tamura H, Mase T, Kosugi K, Morimoto Y, Yoshida K, Toda M. Analysisof Tumor Angiogenesis and Immune Microenvironment in Non-Functional Pituitary
Endocrine Tumors. J Clin Med. 2019;8(5):695.
10) Kosugi K, Tamura R, Ohara K, Morimoto Y, Kuranari Y, Oishi Y, Yoshida K, Toda M.
Immunological and vascular characteristics in cavernous sinus meningioma. J Clin Neurosci.
2019;67:198-203.
11) Tamura R, Ohara K, Morimoto Y, Kosugi K, Oishi Y, Sato M, Yoshida K, Toda M. PITX2Expression in Non-functional Pituitary Neuroendocrine Tumor with Cavernous Sinus
Invasion. Endocr Pathol. 2019;30(2):81-89.
12) Tamura R, Fujioka M, Morimoto Y, Ohara K, Kosugi K, Oishi Y, Sato M, Ueda R, Fujiwara
H, Hikichi T, Noji S, Oishi N, Ogawa K, Kawakami Y, Ohira T, Yoshida K, Toda M. A VEGF
receptor vaccine demonstrates preliminary efficacy in neurofibromatosis type 2. Nat
Commun. 2019;10(1):5758.

13) Kuranari Y, Tamura R, Tsuda N, Kosugi K, Morimoto Y, Yoshida K, Toda M. Long-TermClinical Outcome of First Recurrence Skull Base Meningiomas. J Clin Med. 2019;9(1):106.
14) Yoshida K, Toda M, Yamada Y, Yamada M, Yokoyama Y, Fujiwara H, Kosugi K, Fukumura
M, Koike K, Takahashi S, Yoshida K, Jinzaki M. Sinking skin flap syndrome visualized byupright computed tomography. Acta Neurochir (Wien). 2020;162(8):1825-1828.
15) Kuranari Y, Tamura R, Tsuda N, Kosugi K, Morimoto Y, Yoshida K, Toda M. Prognostic
Significance of Preoperative Neutrophil-to-Lymphocyte Ratio in Patients With Meningiomas.
Front Oncol. 2020;10:592470.
16) Tamura R, Sato M, Morimoto Y, Ohara K, Kosugi K, Oishi Y, Kuranari Y, Murase M, Yoshida
K, Toda M. Quantitative assessment and clinical relevance of VEGFRs-positive tumor cells
in refractory brain tumors. Exp Mol Pathol. 2020;114:104408.
17) Tamura R, Morimoto Y, Sato M, Kuranari Y, Oishi Y, Kosugi K, Yoshida K, Toda M.
Difference in the hypoxic immunosuppressive microenvironment of patients withneurofibromatosis type 2 schwannomas and sporadic schwannomas. J Neurooncol.
2020;146(2):265-273.
18) Kosugi K, Yamada Y, Yamada M, Yokoyama Y, Fujiwara H, Yoshida K, Yoshida K, Toda M,Jinzaki M. Posture-induced changes in the vessels of the head and neck: evaluation using
conventional supine CT and upright CT. Sci Rep. 2020;10(1):16623.
19) Hassaan SA, Tamura R, Morimoto Y, Kosugi K, Mahmoud M, Abokerasha A, Moussa A,Toda M, Yoshida K. Surgical outcomes of anterior cerebellopontine angle meningiomas
using the anterior transpetrosal approach compared with the lateral suboccipital approach.
Acta Neurochir (Wien). 2020;162(6):1243-1248.
20) Tamura R, Morimoto Y, Kosugi K, Sato M, Oishi Y, Ueda R, Kikuchi R, Nagashima H, Hikichi
T, Noji S, Kawakami Y, Sasaki H, Yoshida K, Toda M. Clinical and histopathological analysesof VEGF receptors peptide vaccine in patients with primary glioblastoma - a case series.
BMC Cancer. 2020;20(1):196.
21) Yokoyama Y, Yamada Y, Kosugi K, Yamada M, Narita K, Nakahara T, Fujiwara H, Toda M,Jinzaki M. Effect of gravity on brain structure as indicated on upright computed tomography.
Sci Rep. 2021;11(1):392.
22) Kosugi K, Yoshida K, Suzuki T, Kobayashi K, Yoshida K, Mimura M, Tanaka KF. Activationof ventral CA1 hippocampal neurons projecting to the lateral septum during feeding.
Hippocampus. 2021;31(3):294-304.
23) Yokosako S, Muraoka N, Watanabe S, Kosugi K, Takayama Y, Iijima K, Kimura Y, KanekoY, Sumitomo N, Saito T, Nakagawa E, Iwasaki M. Corpus callosotomy in pediatric patientswith non-lesional epileptic encephalopathy with electrical status epilepticus during sleep.
Epilepsy Behav Rep. 2021;16:100463.
24) Yoshida K, Toda M, Yamada Y, Yamada M, Yokoyama Y, Fujiwara H, Kosugi K, Sasaki H,Jinzaki M. Orthostatic Enlargement of a Supracerebellar Arachnoid Cyst With CerebellarDescent Visualized by Upright Computed Tomography. World Neurosurg. 2021;145:256-259.
25) Takayama Y, Ikegaya N, Iijima K, Kimura Y, Yokosako S, Muraoka N, Kosugi K, Kaneko Y,Yamamoto T, Iwasaki M. Single-Institutional Experience of Chronic Intracranial
Electroencephalography Based on the Combined Usage of Subdural and Depth Electrodes.
Brain Sci. 2021;11(3):307.
26) Takayama Y, Kimura Y, Iijima K, Yokosako S, Kosugi K, Yamamoto K, Shimizu-Motohashi
Y, Kaneko Y, Yamamoto T, Iwasaki M. Volume-Based Radiofrequency Thermocoagulation for
Pediatric Insulo-Opercular Epilepsy: A Feasibility Study. Oper Neurosurg (Hagerstown).
2022;23(3):241-249.
27) Takayama Y, Ikegaya N, Iijima K, Kimura Y, Kosugi K, Yokosako S, Kaneko Y, Yamamoto T,Iwasaki M. Is Hippocampal Resection Necessary for Low-Grade Epilepsy-AssociatedTumors in the Temporal Lobe? Brain Sci. 2022;12(10):1381.
28) Kosugi K, Iijima K, Yokosako S, Takayama Y, Kimura Y, Kaneko Y, Sumitomo N, Saito T,Nakagawa E, Sato N, Iwasaki M. Low EEG Gamma Entropy and Glucose Hypometabolism
After Corpus Callosotomy Predicts Seizure Outcome After Subsequent Surgery. Front Neurol.
2022;13:831126.
29) Tamura R, Oda H, Kosugi K, Toda M. Surgical Planning and Simulation of Endonasal
Endoscopic Surgery for Pituitary Adenoma With Cavernous Sinus Invasion. Oper Neurosurg(Hagerstown). 2022;23(4):e276-e282.
30) Yoshida K, Toda M, Yamada Y, Yamada M, Yokoyama Y, Tsutsumi K, Fujiwara H, Kosugi K,Jinzaki M. Cranial defect and pneumocephalus are associated with significant
postneurosurgical positional brain shift: evaluation using upright computed tomography. Sci
Rep. 2022;12(1):10482.
31) Iwasaki M, Iijima K, Takayama Y, Kawashima T, Tachimori H, Kimura Y, Yokosako S, KosugiK, Kaneko Y. Predictors of Seizure Outcome after Repeat Pediatric Epilepsy Surgery:
Reasons for Failure, Sex, Electrophysiology, and Temporal Lobe Surgery. Neurol Med Chir(Tokyo). 2022;62(3):125-132.
32) Kosugi K, Yoshitomi M, Takayama Y, Iijima K, Kimura Y, Kaneko Y, Toda M, Iwasaki M.
Safety, Feasibility, and Efficacy of Additional Extraventricular Anterior Commissurotomy WithCorpus Callosotomy. Oper Neurosurg (Hagerstown). 2023;24(2):e68-e74.