14th Congress of the European Neuroendocrine
Association
22 - 25 September 2010 Liége - Belgium

ProgramWed. Sept. 22
Opening Ceremony

14.00-14.30
14.30-16.30

S1: Water homeostasis

S2: Neuroendocrine control of bone metabolism

S3: Tumor Stem Cells in Neuroendocrinology

Chairs: Davide Carvalho (Portugal) & Sabina Zacharieva (Bulgaria)

Chairs: Vera Popovic (Serbia) & Roger Bouillon (Belgium)

Chairs: Hugo Vankelecom (Belgium) & Carlos Dieguez (Spain)

Mild hyponatremia: what does it mean? - Steve Ball (UK)New advances in genetic factors regulating metabolism and bonehealth - Carola Zillikens (The Netherlands)

Markers of early embryonic progenitor and stem cell types in the pituitary Karine Rizotti (UK)

Vaptans and the Treatment of Water-balance Peter Gross (Germany)

New neuroendocrine regulators of bone: oxytocin - Alberta
Zallone (italy)

Pituitary cell renewal and its homeostatic regulation during specificphysiological and pathological conditions - Clara Alvarez (Spain)

Inappropiate ADH secretion - Stelios Tsagarakis (Greece)

Oxidative stress, the aging bones - Stavros Manolagas (USA)Stem cells - Tullio Florio (Italy)

Coffee break - Exhibition area

16.30-17.00

Plenary lectures
Chairs : Michael Buchfelder (Germany), Gaetano Lombardi (Italy)
17.30-18.00

L1. Epidemiology of endocrine tumors - Niki Karavitaki (UK/Greece)
L2. MicroRNA and neuroendocrine disorders - Alon Chen (Israel)

18.00-19.00

2009 Fondation IPSEN Endocrine Regulation Prize

19.15-21.00

Welcome Cocktail

17.00-17.30

Thu. Sept. 23
Meet-The-Professor sessions (Parallel sessions)
M1. Challenges in the management of hyperprolactinemia - Marek Bolanowski (Poland)
M2. Pulmonary neuroendocrine tumours - Piero Ferolla (Italy)
M3. Autoimmune hypophisitis - Farhettin Kelestimur (Turkey)
M4. Management of hyperandrogenism in women - Philippe Bouchard (France)

9.00-10.00

Coffee break - Exhibition area

10.00-10.30
10.30-12.30

S4: Problems in hormone assays

S5: Congenital pituitary hormonal deficiencies

Oral Communications Session 1
OC1.1 to OC1.8

Chairs: John Bevan (UK), Galina Melinchencko (Russia)

Chairs : Paolo Beck Peccoz (Italy) & Maria Pfeifer (Slovenia)

Dissecting tissue-specific steroid action in humans using mass
spectrometry and stable isotope tracers - Brian Walker (UK)HESX 1 gene mutations - Juan Pedro Martinez -Barbera (UK)GH-and IGF assay dilemma: the GRS / IFCC consensus - Martin
Bidlingmaier (Germany)

Molecular pathology of the ghrelin receptor- Marie Legendre(France)

Macroprolactinemia - Joe McKenna (Ireland)

Genetic screening strategies in combined pituitary hormonal
deficiencies - Thierry Brue (France)

Lunch & Poster Session 1

12.30-13.30
13.30-15.30

S6: On how sensing fat and time can drive successfulreproduction

S7: AIP function and alteration in pituitary

Oral Communications Session 2Chairs: Felipe Casanueva (Spain), Anton Luger (Austria)

Chairs: Anne Barlier (France), Adrian Daly (Belgium)

OC2.1 to OC2.8

Control of hypothalamic GnRH neurons by metabolic changes : therole of insulin in rodents and in humans - François P. Pralong(Switzerland)

Genetics of AIP - Auli Karhu (Finland)

Kisspeptins beyond a puberty trigger: role in metabolic-reproductive
Molecular targets of AIP in pituitary - Marie Lise Jaffrain Rea (Italy)
integration - Manuel Tena-Sempere (Spain)
As times goes by: hypothalamic neuroendocrine factors in control ofreproduction - Valérie Simonneaux (France)

Clinical characteristics of AIP positive tumors - Maria
Tichomirowa (Belgium)

S8: Somatostatin receptors in health and disease

S9: Neuroendocrinology of Aging Revisited

Oral Communications Session 3

Chairs: Justo Castano (Spain), Anna Spada (Italy)

Chairs: Marily Theodoropoulou (Germany), Elena Grineva (Russia)

OC3.1 to OC3.8

Distinct SOM230- and Octrotide-induced somatostatin receptor
dynamics: are they therapeutically relevant? - Stephan Schulz(Germany)

HPA axis, cortisol secretion and the aging phenotype: a reciprocalinteraction - Jeremy Tomlinson (UK)New PI3K targets as key players for the antitumoral actions of sst2 Corinne Bousquet (France)

IGF-I signaling in the neuroendocrine control of aging: same
same, butdifferent - Martin Holzenberger (France)

New (spoiled?) kids on the block: the truncated variants of sst5 in
pituitary adenomas and cancer - Raul Luque (Spain)

Of NAD+, sirtuins and starving yourself into a healthy old age:new twists in old concepts - TBC

Coffee break - Exhibition area

15.30-16.00
16.00-18.00

18.00-19.30

Novartis Symposium

Fri. Sept.24
Meet-The-Professor sessions (Parallel sessions)
M5: Management of Acromegaly in 2020 - Monica Gadelha (Brazil)
M6: Pitfalls of cortisol replacement - Richard Ross (UK)M7: What a clinician need to know of about molecular biology but never dares to ask - John Kopchick (USA)M8: The influence of BMI adjusted responses on tests investigating pituitary deficiencies - Emanuela Arvat (Italy)

9.00-10.00

Coffee break - Exhibition area

10.00-10.30
10.30-12.30

S10: New insights in cognitive function

S11: MEN syndromes

Oral Communications Session 4

Chairs: Eva Marie Erfurth (Sweden), Marcelo Bronstein (Brazil)

Chairs: Constantine Stratakis (USA), Gregory Kaltsas (Greece)

OC4.1 to OC4.8

Imaging in cognitive dysfunction evaluation - Secondo Lastoria (Italy)

Familial hypercalciuric disorders - Raj V Thakker (UK)

Cognitive impairement in diabetes - Stefania Maggi (Italy)

Multiple endocrine neoplasia type 1 (MEN1): its manifestations
and effect of genetic screening on clinical outcome - Britt
Skogsheid (Sweden)

Cognitive impairement in GH deficiency - Lucia I. Arwert (Netherlands)

Familial paraganglioma disorders - Mercedes Robledo (Spain)
MEN4: Recent advances on p27 pathophysiology - Natalia
Pellegata (Germany)

Lunch & Poster Session 2

12.30-13.30
13.30-15.30

S12: Heterodimerization of GPCR: impact onneuroendocrine physiology and drug discovery

S13: Neuroendocrine tumors

Oral Communications Session 5OC5.1 to OC5.8

Chairs: Diego Ferone (Italy), Christian Strasburger (Gremany)

Chairs: Wouter de Herder (Netherlands), Maria Chiara Zatelli (Italy)

History and biological significance of heterodimerization of GPCR in
neuroendocrine system - Ralf Jockers (France)

Dopamine and somatostatin receptor expression onneuroendocrine tumours. Clinical perspectives - Alexandru
Saveanu (France)

Clinical relevance of somatostatin and dopamine receptor dimerization- Leo J. Hofland (Netherlands)

The mTOR Pathway in neuroendocrine tumors - Simona
Grozinsky-Glasberg (Israel)

GHSR/MC3R heterodimerization in the arcuate nucleus: relevance for Peptide receptor imaging and radiotherapy. Clinical implications body weight regulation - Heike Biebermann (Germany)
Dik Kwekkeoom (Netherlands)

Coffee break - Exhibition area

15.30-16.00

Plenary lectures
Chairs : Monica Marazuela (Spain), Albert Beckers (Belgium)
16.00-16.30

L3. Neuropeptide and inflammation - Mario Delgado (Spain)

16.30-17.00

L4. Glucocorticoid sensitivity in psychiatric diseases - S.W.J.Lamerts (Netherlands)

17.00- 18.00

M9 : Radiotherapy in pituitary tumors - Joseph Marek (CR)M10 : Diabetes insipidus - TBC
M11: Long-term risk of hypopituitarism after childhood cancer - Dr. Shalet (UK)M12: Adrenal carcinoma - TBC

Sat. Sept.25
9.00-10.00

10.00-10.30
10.30-12.30

Meet-The-Professor sessions (Parallel sessions)M13: Management of aggressive pituitary tumors - Ashley Grossman (UK)M14: Clinical aspects in Cushing's syndrome - Susan Webb (Spain)
M15: Benefits and risks of long-term treatment with dopamine agonists for prolactinomas: is it time to change our strategy? - Dominique Maiter (Belgium)
M16: Technical advances in neurosurgical approach to pituitary tumors - P. Nomikos (Greece)
Coffee break - Exhibition area
S14: Neuroendocrinology of Social and Sexual
Oral Communications Session 6BehaviourChairs: Yona Greenman (Israel), Jean-Jacques Legros (Belgium)

OC6.1 to OC6.8

Oxytocin and social behavior in humans - Kerstin Uvanas(Sweden)
Oxytocin, vasopressin and their receptors in behavioral diseases(autism) - Richard Ebstein (Israel)Sexual dysfunctions: the role of gender - Katherine Esposito (Italy)

Plenary lectures
Chairs : Ezio Ghigo (Italy), van der Lely (Netherlands)

L5. Melanocortin Type 4 Receptor as a Target for the Treatment of Obesity and Metabolic Disease - Michael Culler (USA)L6. Neuroendocrine control of glucose metabolism - Christinne Koenner (Germany)