Wendy Hempstock, PhD
https://db.u-shizuoka-ken.ac.jp/show/n-hempstock.html
https://researchmap.jp/wlh
https://www.researchgate.net/profile/Wendy-Hempstock

Education
PhD in Food and Nutritional Science, University of Shizuoka, Shizuoka, Japan, 2021
Master of Science in Human Nutrition, University of British Columbia, Vancouver,Canada, 2014
Bachelor of Science in General Science with a minor in Russian Studies, University ofBritish Columbia, Vancouver, Canada, 2008

Employment
University of Shizuoka, Faculty of Food and Nutritional Science, Assistant Professor,
2024-present
University of Shizuoka, School of Nursing, Assistant Professor, 2021-2024
University of Shizuoka, School of Nursing, Sessional Lecturer, 2020-2021
Saitama Prefectural Board of Education, Assistant Language Teacher, 2012-2017
Leonis Management & Consultants Ltd., Accounting Clerk, 2005-2012

Professional Memberships
The Physiology Society, Physiology News Editorial Board Member, 2019-present
Japanese Physiology Society, Full member, 2019-present
AAAS, Gold member, 2023-present

Teaching Experience
English: High-school level current affairs, cross-cultural communication, debate, drama,
writing and presentation skills
Science: University level biochemistry (1st year students), health science lab course (1styear students), and food chemistry tutorial (3rd year students)
Research Advisor: University level graduation research supervisor (4th year students)

Publications
Nakamura, C., Ishizuka, N., Yokoyama, K., Yazaki, Y., Tatsumi, F., Ikumi, N., Hempsto
ck, W., Ikari, I., Yoshino, Y., & Hayashi, H. (2023). Regulatory mechanisms of glucose absorption in the mouse proximal small intestine during fasting and feeding. Scientific Reports, 13:10838. DOI: https://doi.org/10.1038/s41598-023-38024-w
Hempstock, W., Nagata, N., Ishizuka, N., & Hayashi, H. (2023). The effect of claudin-15
deletion on cationic selectivity and transport in paracellular pathways of the cecum and large intestine. Scientific Reports, 13:6799. DOI: https://doi.org/10.1038/s41598-023-334
31-5
Ishizuka, N., Nagahashi, M., Mochida, Y., Hempstock, W., Nagata, N., & Hayashi, H. (2023). Na+-dependent intestinal glucose absorption mechanisms and its luminal Na+ homeostasis across metamorphosis from tadpoles to frogs. AJP Regul. Integr. Comp. Physiol. 3
24(5): R645-R655. DOI: https://doi.org/10.1152/ajpregu.00249.2021
Furuse, M., Nakatsu, D., Hempstock, W., Sugioka, S., Ishizuka, N., Furuse, K., Sugawara,T., Fukazawa, Y., & Hayashi, H. (2023). Reconstitution of functional tight junctions wit
h individual claudin subtypes in epithelial cells. Cell Structure and Function. 48(1): 1-17.
DOI: https://doi.org/10.1247/csf.22068.
Hempstock, W., Ishizuka, N., & Hayashi, H. (2021). Functional assessment of intestinal tight junction barrier and ion permeability in native tissue by Ussing chamber technique. J.
Vis. Exp. 171: e62468. DOI: https://dx.doi.org/10.3791/62468
Hempstock, W., Sugioka, S., Ishizuka, N., Sugawara, T., Furuse, M., & Hayashi, H.
(2020). Angulin-2/ILDR1, a tricellular tight junction protein, does not affect watertransport in the mouse large intestine. Scientific Reports, 10: 10374. DOI:
https://doi.org/10.1038/s41598-020-67319-5
Nakayama, M., Ishizuka, N., Hempstock, W., Ikari, A., & Hayashi, H. (2020). Na+Coupled Nutrient Cotransport Induced Luminal Negative Potential and Claudin-15 Playan Important Role in Paracellular Na+ Recycling in Mouse Small Intestine. Int. J. Mol.
Sci., 21(2). 376. DOI: https://doi.org/10.3390/ijms21020376

Ishizuka, N., Hempstock, W. & Hayashi, H. (2019). The Mode of Action of NHE3
Inhibitors in Intestinal Na+ Absorption. Gastro Med Res. 4(1). 297. DOI:
https://doi.org/10.31031/GMR.2019.04.000577
Hempstock, W. (2014). Effects of short-term supplementation of folic acid and L-5methyltetrahydrofolate on cell proliferation and the expression of folate transporters inhuman colorectal adenocarcinoma (Caco2) cells (Master’s thesis). Retrieved from Open
Access Theses and Dissertations database. (Record ID: handle:2429/46541)
Wiebe, E. & Hempstock, W. (2008) Comparison of four regimens of misoprostol after
methotrexate for early abortion. Int. J. Gynecology & Obstetrics 101: 192-193.

Conferences and Presentations
March 14-16, 2023: Japanese Physiology Society’s 100th Annual Meeting (Kyoto, Japan)• Symposium Presentation: Claudin-15 is responsible for the conductance andpermselectivity of the murine cecum and large intestine

September 16-18, 2022: Europhysiology 2022 (Copenhagen, Denmark)• Poster Presentation: Claudin-15 is the molecule responsible for the conductanceand permselectivity of the murine cecum and large intestinal epithelia
March 16-18, 2022: The 99th Annual Meeting of the Physiological Society of Japan(Sendai, Japan)• Oral Presentation: The effect of claudin-15 deletion on digestion and energy
metabolism
December 6-8, 2021: Frontiers in Epithelial Cell Biology (Internet-based conference)• Poster Presentation: The effect of claudin-15 deletion on paracellular Na+
transport in the cecum and large intestine
October 16-20, 2020: The 67th Annual Central Japan Physiology Conference (Internetbased conference)• Oral Presentation: Effect of claudin 15 knockout in the murine cecum and largeintestine
March 17-19, 2020: The 97th Annual Meeting of the Physiological Society of Japan (Oita,Japan)

•Oral Presentation: Intestinal nutrient absorption and barrier function in SAMP1
senescence accelerated aged mice

November 11, 2019: 2019 Sendai Shirahakugo Women’s University HumanDevelopment Research Centre Lecture Series: The 1st Health and Epithelial Transport
Research Meeting (Sendai, Japan)• Invited Speaker: Barrier integrity and paracellular transport are maintained in thelarge intestine of ILDR1 knockout mice
November 9-10, 2019: The 24th Shizuoka Forum on Health and Longevity (Shizuoka,Japan)•

Poster Presentation: Paracellular transport across tricellular tight junctions in thelarge intestine of ILDR1 knockout mice

September 5-6, 2019: 2019 National Institute for Physiological Sciences Research
Meeting: Strategies for elucidating the functional relationship between epithelium, stroma
and the pathogenesis mechanism (Okazaki, Japan)•

Oral Presentation: Paracellular transport across tricellular tight junctions in thelarge intestine of ILDR1 knockout mice

July 8-10, 2019: Physiology 2019 (Aberdeen, UK)•Poster Presentation: Paracellular water and ion transport is unaffected in ILDR1knockout mice

May 17-19, 2019: 73rd Annual Japan Society for Nutritional and Food Science Meeting(Shizuoka, Japan)•Oral Presentation: Paracellular ion and water transport is unaffected in the large
intestine of ILDR1 KO mice