Structure
HO

SMILESIUPACNameMW

Plate description

CAS

Catalog number

Concentration

Compound description

Solvent

Plate part number

CH3
COOH
COOH

H

[H][C@]12CC[C@]([H])(O1)[C@](C)(C(O)=O)[C@]2(C)C(O)=O(1R,2S,3R,4S)-2,3-dimethyl-7-oxabicyclo[2.2.1]heptane-2,3-dicarboxylic acid

Cantharidic acid214.2

Phosphatase Inhibitor Library

28874-45-5

PR-10610mM

PP1 and PP2A

DMSO

2834

[H][C@]12CC[C@]([H])(O1)[C@]1(C)C(=O)OC(=O)[C@]21C(1R,2S,6R,7S)-2,6-dimethyl-4,10-dioxatricyclo[5.2.1.0²,⁶]decane-3,5-dione

Cantharidin

196.2

Phosphatase Inhibitor Library56-25-7

PR-10510mM

PP1 and PP2A

DMSO

2834

[H][C@]12CC[C@]([H])(O1)C(C2C(O)=O)C(O)=O(1R,4S)-7-oxabicyclo[2.2.1]heptane-2,3-dicarboxylic acid

Endothall

186.2

Phosphatase Inhibitor Library

145-73-3

PR-107

10mM

PP2A

DMSO

2834

OP(O)(=O)CC1=CC=CC=C1

benzylphosphonic acid

Benzylphosphonic acid

172.1

Phosphatase Inhibitor Library

6881-57-8

EI-24410mM

Tyrosine phosphatases

DMSO

2834

OC(=O)C(O)=O.BrC1=CC=C(C=C1)[C@H]1CN2CCSC2=N1(6S)-6-(4-bromophenyl)-2H,3H,5H,6H-imidazo[2,1-b][1,3]thiazole; oxalic acid

L-p-Bromotetramisole oxalate

373.2

Phosphatase Inhibitor Library

62284-79-1

T-100

10mM

Tyrosine phosphatases

DMSO

2834

CCCCCCCCCCCCCCCC(=O)C1=C(O)C(CO)OC1=O

3-hexadecanoyl-4-hydroxy-5-(hydroxymethyl)-2,5-dihydrofuran-2-one

RK-682368.5

Phosphatase Inhibitor Library

154639-24-4

PR-11210mM

Tyrosine phosphatases

DMSO

2834

OC(C1=CC(=CC=C1OC1=CC=C(Br)C=C1)[N+]([O-])=O)P(O)=O{[2-(4-bromophenoxy)-5-nitrophenyl](hydroxy)methyl}phosphinic acid

RWJ-60475

388.1

Phosphatase Inhibitor Library

204130-08-5PR-109

10mM

CD45 tyrosine phosphatase

DMSO2834

CC(=O)OCOC(C1=CC(=CC=C1OC1=CC=C(Br)C=C1)[N+]([O-])=O)P(=O)(OCOC(C)=O)OCOC(C)=O({[(acetyloxy)methoxy]({[(acetyloxy)methoxy][2-(4-bromophenoxy)-5-nitrophenyl]methyl})phosphoryl}oxy)methyl acetate

RWJ-60475 (AM)3620.3

Phosphatase Inhibitor Library

1069116-45-5

PR-11010mMCD45 tyrosine phosphatase (cell permeable)

DMSO2834Cl.C1CN2C[C@@H](N=C2S1)C1=CC=CC=C1(6S)-6-phenyl-2H,3H,5H,6H-imidazo[2,1-b][1,3]thiazole hydrochloride

Levamisole HCl

240.8

Phosphatase Inhibitor Library

16595-80-5

AC-110210mM

Mammalian alkaline phosphatase

DMSO

2834

Cl.C1CN2CC(N=C2S1)C1=CC=CC=C1

6-phenyl-2H,3H,5H,6H-imidazo[2,1-b][1,3]thiazole hydrochloride

Tetramisole HCl

240.8

Phosphatase Inhibitor Library

5086-74-8

AC-1104

10mM

Mammalian alkaline phosphatase

DMSO

2834

CC1(C)C(C=C(Cl)Cl)C1C(=O)OC(C#N)C1=CC=CC(OC2=CC=CC=C2)=C1(3-phenoxyphenyl)(cyano)methyl 3-(2,2-dichloroethenyl)-2,2-dimethylcyclopropane-1-carboxylate

Cypermethrin

416.3

Phosphatase Inhibitor Library

52315-07-8

PR-10010mM

Calcineurin (PP2B)

DMSO

2834

CC1(C)[C@@H](C=C(Br)Br)[C@H]1C(=O)O[C@H](C#N)C1=CC(OC2=CC=CC=C2)=CC=C1(S)-(3-phenoxyphenyl)(cyano)methyl (1R,3R)-3-(2,2-dibromoethenyl)-2,2-dimethylcyclopropane-1-carboxylate

Deltamethrin

505.2

Phosphatase Inhibitor Library

52918-63-5

PR-10110mM

Calcineurin (PP2B)DMSO2834

CC(C)C(C(=O)OC(C#N)C1=CC=CC(OC2=CC=CC=C2)=C1)C1=CC=C(Cl)C=C1(3-phenoxyphenyl)(cyano)methyl 2-(4-chlorophenyl)-3-methylbutanoate

Fenvalerate

419.9

Phosphatase Inhibitor Library

51630-58-1

PR-10210mM

Calcineurin (PP2B)

DMSO

2834

COC1=CC=C(C=C(C#N)C#N)C=C1

2-[(4-methoxyphenyl)methylidene]propanedinitrile

Tyrphostin 8

184.2

Phosphatase Inhibitor Library

2826-26-8

PR-11310mM

Calcineurin (PP2B)

DMSO

2834

CC(C)C[C@H](NC(=O)[C@H](CCC(O)=O)NC(=O)CNC(=O)C1=CC=C(C=C1)\C=C\C(O)=O)C(N)=O(4S)-4-{[(1S)-1-carbamoyl-3-methylbutyl]carbamoyl}-4-[2-({4-[(1E)-2-carboxyeth-1-en-1-yl]phenyl}formamido)acetamido]butanoic acid

CinnGel490.5

Phosphatase Inhibitor Library

172796-68-8

PR-114

10mM

PTP1B

DMSO

2834

OCCSC1=C(SCCO)C(=O)C2=C(C=CC=C2)C1=O

2,3-bis[(2-hydroxyethyl)sulfanyl]-1,4-dihydronaphthalene-1,4-dione

NSC-95397

310.4

Phosphatase Inhibitor Library

93718-83-3

EI-309

10mM

Cdc25

DMSO

2834

COC1=C(O)C(CN(C)CCC2=CC=C(C=C2)[N+]([O-])=O)=CC(=C1)N(C)C

4-(dimethylamino)-2-methoxy-6-({methyl[2-(4-nitrophenyl)ethyl]amino}methyl)phenol

BN-82002

359.4

Phosphatase Inhibitor Library

396073-89-5

PR-124

10mM

DMSO

2834

CC(C)=CC[C@@H](O)C1=CC(=O)C2=C(O)C=CC(O)=C2C1=O

5,8-dihydroxy-2-[(1R)-1-hydroxy-4-methylpent-3-en-1-yl]-1,4-dihydronaphthalene-1,4-dione

Shikonin

288.3

Phosphatase Inhibitor Library

517-89-5

CT-115

10mM

DMSO

2834

ClC1=C(NCCN2CCOCC2)C(=O)C2=C(C=CC=N2)C1=O6-chloro-7-{[2-(morpholin-4-yl)ethyl]amino}-5,8-dihydroquinoline-5,8-dione

NSC-663284

321.8

Phosphatase Inhibitor Library

383907-43-5

PR-116

10mM

CDC25

DMSO

2834

CC[C@@H]1NC(=O)[C@H]([C@H](O)[C@H](C)C\C=C\C)N(C)C(=O)[C@H](C(C)C)N(C)C(=O)[C@H](CC(C)C)N(C)C(=O)[C@H](CC(C)C)N(C)C(=O)[C@@H](C)NC(=O)[C@H](C)NC(=O)[C@H](CC(C)C)N(C)C(=O)[C@@H](NC(=O)[C@H](CC(C)C)N(C)C(=O)CN(C)C1=O)C(C)C(3S,6S,9S,12R,15S,18S,21S,24S,30S,33S)-30-ethyl-33-[(1R,2R,4E)-1-hydroxy-2-methylhex-4-en-1-yl]-1,4,7,10,12,15,19,25,28-nonamethyl-6,9,18,24-tetrakis(2-methylpropyl)-3,21-bis(propan-2-yl)-1,4,7,10,13,16,19,22,25,28,31-undecaazacyclotritriacontan-2,5,8,11,14,17,20,23,26,29,32undecone

Cyclosporin A

1202.6 Phosphatase Inhibitor Library

59865-13-3

A-105

10mM

Calcineurin (PP2B)

DMSO

2834

NC(=N)C1=CC=C(OCCCCCOC2=CC=C(C=C2)C(N)=N)C=C1

4-{[5-(4-carbamimidoylphenoxy)pentyl]oxy}benzene-1-carboximidamide

Pentamidine

340.4

Phosphatase Inhibitor Library

100-33-4

PR-11810mM

PRL1DMSO

2834

CC1(C)C(=O)N=C2C1=C(O)C(=O)C1=C2C=CC=C1

4-hydroxy-3,3-dimethyl-2H,3H,5H-benzo[g]indole-2,5-dione

BVT-948241.2

Phosphatase Inhibitor Library

39674-97-0

PR-12510mM

Tyrosine phosphatases

DMSO

2834

BrC1=CC=C(OCC2=C(Br)C=CC=C2)C(\C=C2/SC(=S)NC2=O)=C1(5Z)-5-({5-bromo-2-[(2-bromophenyl)methoxy]phenyl}methylidene)-2-sulfanylidene-1,3-thiazolidin-4-one

B4-Rhodanine

485.2Phosphatase Inhibitor Library

893449-38-2

PR-12610mM

PRL3DMSO

2834

Cl.Cl.CCCCC(CC)CNC(=N)NC(=N)NCCCCCCNC(=N)NC(=N)NCC(CC)CCCC

N-(2-ethylhexyl)-1-3-(6-{N-[3-(2-ethylhexyl)carbamimidamidomethanimidoyl]amino}hexyl)carbamimidamidomethanimidamide dihydrochloride

Alexidine·2HCl

581.7

Phosphatase Inhibitor Library

1715-30-6

AC-156210mM

PTPMT1DMSO

2834

O=C1C(=O)C2=CC=CC=C2C2=CC=CC=C12

9,10-dihydrophenanthrene-9,10-dione

9,10-Phenanthrenequinone

208.2

Phosphatase Inhibitor Library

84-11-7

AC-140210mM

CD45 tyrosine phosphatase

DMSO

2834

OC(=O)C1=CC=C(C=C1)N1C(=S)S\C(=C/C2=CC=CC=C2)C1=O

4-[(5Z)-4-oxo-5-(phenylmethylidene)-2-sulfanylidene-1,3-thiazolidin-3-yl]benzoic acidBML-260

341.4

Phosphatase Inhibitor Library

862827-45-0

PR-119

10mM

JSP-1

DMSO

2834

[Cl-].C[N+]1=CC2=C(C=CC3=C2OCO3)C2=C1C1=C(C=C2)C=C2OCOC2=C1

24-methyl-5,7,18,20-tetraoxa-24-azahexacyclo[11.11.0.0²,¹⁰.0⁴,⁸.0¹⁴,²².0¹⁷,²¹]tetracosa-1(13),2(10),3,8,11,14(22),15,17(21),23-nonaen-24-ium chloride

Sanguinarine chloride

367.8

Phosphatase Inhibitor Library

5578-73-4

AC-1563

10mM

PP2C

DMSO

2834

OC(=O)C(F)(F)F.CN1CCC2=C(C1)SC(NC(=O)C(O)=O)=C2C(O)=O

2-(carboxyformamido)-6-methyl-4H,5H,6H,7H-thieno[2,3-c]pyridine-3-carboxylic acid; trifluoroacetic acidBML-267

398.3

Phosphatase Inhibitor Library

PR-121

10mM

PTP1B

DMSO

2834

CCOC(=O)C(=O)NC1=C(C(=O)OCC)C2=C(CN(C)CC2)S1

ethyl 2-(2-ethoxy-2-oxoacetamido)-6-methyl-4H,5H,6H,7H-thieno[2,3-c]pyridine-3-carboxylate

BML-267 Ester

340.4

Phosphatase Inhibitor Library

474843-73-7

PR-12910mM

PTP1B (cell permeable)

DMSO

2834

OC(=O)C(=O)NC1=CC=CC=C1C(O)=O

2-(carboxyformamido)benzoic acid

OBA

209.2

Phosphatase Inhibitor Library

5651-01-4

PR-12210mM

Tyrosine phosphatases

DMSO

2834

CCOCC(=O)C(=O)NC1=CC=CC=C1C(O)=O

2-(3-ethoxy-2-oxopropanamido)benzoic acid

OBA Ester

251.2

Phosphatase Inhibitor Library

PR-13010mM

Tyrosine phosphatases (cell permeable)

DMSO

2834

CC(C)C1=C(O)C(O)=C(C=O)C2=C1C=C(C)C(=C2O)C1=C(O)C2=C(C=C1C)C(C(C)C)=C(O)C(O)=C2C=O

7-[8-formyl-1,6,7-trihydroxy-3-methyl-5-(propan-2-yl)naphthalen-2-yl]-2,3,8-trihydroxy-6-methyl-4-(propan-2-yl)naphthalene-1-carbaldehyde

Gossypol518.6

Phosphatase Inhibitor Library

303-45-7

EI-13010mM

Calcineurin (PP2B)

DMSO

2834

[Na+].NCCCC(O)(P(O)(O)=O)P(O)([O-])=O

sodium hydrogen (4-amino-1-hydroxy-1-phosphonobutyl)phosphonate

Alendronate

271.1

Phosphatase Inhibitor Library

121268-17-5

PR-12310mMTyrosine phosphatases

DMSO2834

CH3HO

O

CH3O
HCH3O

O HOH

O

HO
HOO

OHPHOHOO

OOHN

Br
NO

HOS

O
CH 3HOOBrOOHOHPHONO 2Br

OOOO

CH 3O

O

CH 3POOOONO 2CH 3O

HClNNSHClNS
NNO
H 3C

O
O

H 3C
Cl

Cl

H C

CH 33Br

O

Br

OO
N

H 3C
CH 3Cl
OO

O

N

N
CH3O

NiBu

H
N

H NOOO
O2OH
HNNH

HOOCOOSOHOH

SOO–CH 3H 3C

N

H 3C

ON+H 3CNOOHOOHOOH

CH3H3 COH

OClONNHNO

H 3C

CH 3H 3C
H 3C

CH 3O

CH 3O
HN

NOO

CH 3O

NO
HNN
HO
CH 3CH 3H 3C

O

CH 3HNN

CH 3CH 3H 3C

CH 3O

H 3C

NO

CH 3CH 3H 3C

O
N

CH 3H 3C

HON

N

H 3C

CH 3H 3C

HNO
H N2ONH
H N
2O
N

CH3CH3OH

O

Br
OONH
S
S

Br

H C

CH33HNHClNH

HNNHHNNH

HNNH

NH

NH

HCl
H C

CH33OOOOOHNSSCl –OO

H 3C

N+OOOOH
OHNN

S

H 3C

O

OH

F3 C

COOH

CH 3OOO
H 3C

NO

CH 3N
HSOOOHNH

O
HOO
OOH

NH

O
H3 C

O
O

H 3C
O

CH 3H 3C
OH

OH

HOOH
OH
CH 3HO

H 3C

O
HOHOO

CH 3O

PPOH

NH 2OHO –Na +