FEATURES

ᰋ Watt-level output at high repetition rate for fast imaging
ᰋ Two tunable and one fixed output for simultaneous
multibeam excitation

ᰋ Automated GDD control for shortest pulses at the sample

ᰋ Industrial-grade design for high power and beam stability

CRONUS-2P is a femtosecond laser providing watt-level threesynchronized outputs with high repetition rate, short pulse
duration, and GDD control, making it the ultimate sourcefor nonlinear microscopy. In standard configuration, thetwo independently tunable outputs, operating separately
or simultaneously, cover 680 – 960 nm and 960 – 1300 nm,
respectively, while the third is fixed at 1025 nm and isaccessible in parallel. Thus, the CRONUS-2P can be used
for simultaneous excitation of multiple fluorescent probes,
calcium indicators, or opsins at their absorption maxima,

whereas second- and third‑harmonic emission (SHG and THG)
can be spectrally shifted for ease of detection or resonantenhancement.
The two tunable and simultaneous channels also enableadvanced coherent anti-Stokes and stimulated Raman
scattering (CARS and SRS) applications with dual-bandimaging, a broader selection of vibrational resonancefrequencies, constant-difference dual‑beam tuning, resonant
enhancement, and more.

104.0
3.503.0
2.5

GDD, 103 fs2

Output power, W

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Three-Channel Wavelength-Tunable Femtosecond Laser

2.0

Output A
Output B
Output C

1.5

1.0700800-10-20
Output A
Output B
Specification range-309001000

1100

1200-401300

700

800

90010001100Wavelength, nm

Wavelength, nm

CRONUS-2P tuning curve

GDD control range

12001300-145
Output A
Output B
Output C

3.2
Output power, W

RIN, dBc/Hz-150

λ = 900 nm
NRMSD = 0.15%-155-160

3.0

Shot noise
2.8-165

0.2

0.4

0.6

0.8 1.0
2.0Frequency, MHz

4.0

CRONUS-2P relative intensity noise (RIN)

68

6.0

8.0 10.0

0200

400

600
Time, h800

1000

1200

Typical output power stability of CRONUS-2P at 900 nm

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CRONUS-2PModel
Output AOutput B

Output C

Tuning range 1)

680 – 960 nm

960 – 1300 nm

1025 nm (fixed)

Output power 2)> 3 W @ 920 nm> 2.5 W @ 1100 nm> 2.5 W

Pulse duration 3) 4)< 160 fs

Repetition rate

77 ± 1 MHz

Beam quality, M< 1.22 3)

Polarization

Linear, horizontal

Beam divergence, full angle< 1 mradBeam diameter 3) (1/e²)< 1.5 mrad

3.0 ± 0.4 mm

3.2 ± 0.4 mm

Beam ellipticity 3)
Beam astigmatism

2.8 ± 0.4 mm> 0.8< 20%3)

Beam pointing stability 5)< 200 µradn/aLong-term power stability, 24 h 3) 6)< 1%−10000 to −35000 fs² @ 700 nm−3000 to −20 000 fs² @ 800 nm
0 to −10 000 fs² @ 960 nm

GDD control range

0 to −10 000 fs² @ 960 nm−3000 to −10 000 fs² @ 1100 nm−6 000 to −12 000 fs² @ 1300 nm

n/a

OPTIONAL WAVELENGTH EXTENSIONS (UV – VIS)
Second harmonic tuning range

340 – 480 nm

480 – 650 nm

Conversion efficiency at peak

> 30%

n/a

ENVIRONMENTAL REQUIREMENTS
Altitude< 2000 m

Temperature, operating

18 – 30 °C

Temperature, storage

10 – 35 °CRelative humidity, operating< 80% (non-condensing)

DIMENSIONS
Laser head (L × W × H)

806 × 528 × 311 mm

Rack for power supply and chiller (L × W × H)

642 × 553 × 673 mm

Configuration with dual-output A or dual-output B is also available.
Simultaneous mode: > 1 W @ 920 nm, > 1 W @ 1100 nm, and > 2.5 W @ 1025 nm.
3)
Speficied at 920 nm, 1100 nm, and 1025 nm, respectively.
4)
IR pulse duration determined assuming sech2 shape.
5)
Beam pointing deviation over the entire tuning and GDD control range.
6)
Expressed as NRMSD (normalized root mean squared deviation); with less than ±1 °C temperature change after 1 h warm up.
1)
2)

Side view

901.6
806

Front view

120.8311

260

13625575

Top view

7.5

219.7

248

DANGER: VISIBLE AND/OR INVISIBLE
LASER RADIATION AVOID EYE OR SKINEXPOSURE TO DIRECT, REFLECTEDOR SCATTERED RADIATION

CLASS 4 LASER PRODUCTSCIENTIFIC APPLICATIONS | MICROSCOPY SOURCES | SPECTROSCOPY SYSTEMS | OPCPA SYSTEMS | WAVELENGTH-TUNABLE SOURCES | FEMTOSECOND LASERSSPECIFICATIONS

Laser output 680 – 960 nm

50550528275

Laser output 1025 nm fixed
Laser output 960 – 1300 nm

CRONUS-2P drawing

www.phototechnica.co.jp
REV. 230105 | SALES@LIGHTCON.COM | WWW.LIGHTCON.COM〒336-0017 埼玉県さいたま市南区南浦和 1-2-17

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e-mail:voc@phototechnica.co.jp

69

FEATURESᰋ High pulse energy for deep imaging

ᰋ 1250 – 1800 nm tuning range for 3P imaging

ᰋ Down to 50 fs pulse duration for high peak power

ᰋ Automated wavelength and GDD control for optimal signalᰋ Market-leading pulse-to-pulse energy stability

CRONUS-3P is a laser source developed for advanced
nonlinear microscopy. It provides µJ-level pulses down to50 fs at repetition rates of up to 2 MHz and tunable in the
short-wavelength infrared (SWIR) range from 1250 to 1800 nm,
thus covering the biological transparency windows at 1300
and 1700 nm for three-photon (3P) microscopy. In addition,
CRONUS-3P offers simultaneous 1030 nm amplifier andoscillator outputs.

Typically, multiphoton imaging in the SWIR range requires acomplex multi-device laser system, a large optical table, andskilled staff. This reality encumbers neuroscience and otherbiomedical applications. The CRONUS-3P system is a nextgeneration, industrial-grade, single-supplier solution that ismore compact, more reliable, and more versatile. It achieves
tunable femtosecond excitation with integrated group delay
dispersion (GDD) control, ensuring optimal pulse duration at
the sample, while industrial-grade design guarantees highpulse-to-pulse energy and long-term power stability.

1520002.01000

1.010GDD, 103 fs2

Pulse energy, µJ5Output power, mW

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Laser Source for Advanced Nonlinear Microscopy

0-5500

0.5

400

0.4

-10

0.3

-15

0.2
1800

-20

Output without GDD control
Output with GDD control

300

Specification range

200
1300

1400

1500
Wavelength, nm

1600

1700

Output power and pulse energy vs wavelength.
Pump: 40 W, 1 MHz.

1.01300 nm

1.3

1.4

1.5
1.6
Wavelength, µm

1.7

1.8

GDD control range

1700 nmIntensity, a.u.

0.8
0.6

47.0 fs

56.7 fs

0.4
0.2
0.0-300-200-100

0100
Delay, fs

200 300 -300 -200-100

0100
Delay, fs

200 300

Typical pulse duration at 1300 nm and 1700 nm

66

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ModelCRONUS-3P

Tuning range 1)1250 – 1800 nm

Repetition rate 2)

Single-shot to 2 MHz
1300 nm1700 nm

Pulse duration< 50 fs< 65 fs

Output power> 1100 mW @ 1 MHz> 800 mW @ 2 MHz> 800 mW @ 1 MHz> 500 mW @ 2 MHz−4000 to +9000 fs2−12000 to +3500 fs2GDD control range 3)
Beam diameter3 – 5 mm4)

Beam quality (M²)

< 1.2

Beam ellipticity> 0.8

Beam divergence< 1 mradLong-term power stability, 24 h 5)

< 1%

Pulse-to-pulse energy stability, 1 min 5)< 1%

MAIN OUTPUT WITHOUT GDD CONTROL> 1500 mW @ 1 MHz> 1000 mW @ 2 MHz

Output power> 1050 mW @ 1 MHz> 700 mW @ 2 MHz

ADDITIONAL OUTPUTS
Auxiliary 1030 nm amplifier output

1030 ± 10 nm, up to 40 W, up to 2 MHz, < 250 fs

Optional 1030 nm oscillator output

1030 ± 10 nm, up to 500 mW, ≈ 65 MHz, ≈ 200 fs

Alternative 2P+3P configuration with extended tuning range to 650 – 920 nm is available, contact sales@lightcon.com.
2)
Lower repetition rate with higher pulse energy option available.
3)
Continuous dispersion control; −3000 fs2 compensates a microscope with +3000 fs2.
4)
1/e2, measured at compressor output.
5)
Expressed as NRMSD (normalized root mean squared deviation).
1)

DANGER: VISIBLE AND/OR INVISIBLE
LASER RADIATION AVOID EYE OR SKINEXPOSURE TO DIRECT, REFLECTEDOR SCATTERED RADIATION

CLASS 4 LASER PRODUCT

λ = 1300 nm

Output power, W

λ = 1300 nm
NRMSD = 0.35%
1.4

NRMSD = 0.29%

1.3

050

100150Time, h200

250

Typical long-term power stability at 1300 nm

300

0.96

0.98

1.00
Pulse energy, a.u.

1.02

1.04

Typical pulse-to-pulse energy distribution at 1300 nm

838

Reference Pointfor Metric Table

16.4

Reference Point
for Imperial Table

26.2

Main Output
h = 12530560

Beam profile at 1300 nm,
4.2 mm diameter (1/e2)

25125
13.3
8.5(110)(585)

350785SCIENTIFIC APPLICATIONS | MICROSCOPY SOURCES | SPECTROSCOPY SYSTEMS | OPCPA SYSTEMS | WAVELENGTH-TUNABLE SOURCES | FEMTOSECOND LASERS

SPECIFICATIONS

Alternative Output
h = 125

CRONUS-3P drawing

www.phototechnica.co.jp
REV. 230105 | SALES@LIGHTCON.COM | WWW.LIGHTCON.COM〒336-0017 埼玉県さいたま市南区南浦和 1-2-17

TEL:048-871-0067 FAX:048-871-0068

e-mail:voc@phototechnica.co.jp

67