JUPITERSINGLE & PARALLELMINIFERMENTER
BIOREACTORJUPITER
This technical proposal describes a Solaris JUPITER.

For supervisory control and data acquisition Leonardo 3.0 isincluded.
The system consists of jacketed fermenter/bioreactor(total volume), bench-top, pre-assembled unit, supplied withall necessary tubes, valves and instruments, automation,
control panel (HMI).
The system is designed for aerobic and anaerobic
cultivations/ fermentations, closed aseptic operations.
The control is based on a SCADA control system.

Customizable
Configurationdifferente aspect ratio and thermoregulation strategies
Applications

Process development
and optimization

Education

Basic Research Scale up and scale-down Small production
studiesAspect Ratio available:- D/H 3:1
- D/H 2:1

Jacketed and single-wallborosilicate glass vessel designs
available for all volumes
Different gas mixing strategies withup to 5 TMFC and/or solenoid
valves, jacketed design : fully
removable and cleanable glass
jacket for improved heat transfer
during autoclaving and single-walldesign: thermoregulation performed
with heating blanket and cooling
finger.

Modbus digital sensors reduce
background noise and guarantee
quick response time
Suitable for batch, fed-batch andcontinuous processes

Powerful and accurate (1 RPM)
brushless motor

Wide range of measurement andcontrol options
Optional integration of up to 4
analog input/output connections,choosing between 0-10 V and 0-20
mA/4-20 mA (e.g. pumps or valves
with power supply independent
from Solaris electrical cabinet)

Sterile septum with single use
membrane for manual feeding
Leda: the innovative sterilesampling system for Solaris'
autoclavable
fermenters/bioreactors, which allows up to 180
sterile samplings per batchPressure control up to 1.6 bar (withconstant gas-in and gas-out flux)
available in the 2 and 4 L volumes
with jacketed design.

Leonardo

Innovative SCADA software​L​ EONARDO​: a smart and userfriendly controller designed to provide a high level of automatedmanagement of the fermentation/cultivation processes
Full version included in the equipment supply
Up to 24 units managed in parallel with a unique HMI (​24”)
Data extraction in .csv format
Remote access via PC, tablet or smartphone, with QR code
scanning or dedicated portal
Remote control

Synoptic
real time 3D view

LogicParser
customized logic

RemoteControl
unlimited number ofTrends
custom acquisition time

Workflowcustom phase manager

Calibration
up to three-point

parallel control
manual control

profiles editor
unlimited number ofdevices to be associatedparallel visualizationcascade settings
peristaltic pumps function
assignable from software

functionsparallel logic blocks andfuntions

up to 6 values
simultaneously display
automatic graphcomparison

calibration
simoultaneus calibration
values for parallel work

VesselSolaris Code
Production CodeTotal Volume (L)Ratio D/H
Min. Working Volume (L)Max. Working Volume (L)Max. temperature
Operating pressure

Headplate ports(n.10 in Jupiter 2.0;
n.13 in the others)
DesignMaterials
Sensors length (mm)pH
dO₂

Jupiter 2.0
jpt110300
2.00
1:3,0
0,35
1,40

Jupiter 4.0
jpt130395
4.00
1:3,0
0,60
2,80

Jupiter 6.5 Jupiter 8.0
jpt160395 jpt160480
6,50
8,00
1:2,5
1:3,0
1,10
1,10
4,50
5,50
70 °C
< 0.5 bar
Jupiter 2.0 and 4.0: optionally < 1.6 bar

Jupiter 10.0
jpt180480
10,00
1:3,0
1,60
7,0

Borosilicate Glass Jacketed VesselBorosilicate Glass and AISI 316 L425425425425425425705
315

790315790
335(optional) Watson Marlow type 313 FDM/D, max. speed 350 rpm, volumetric flow, 1,5-1750 ml/min, function assignable from softwaren. 4 Watson Marlow type 114, fixed speed, max. 60 rpm, volumetric flow 0,5-51 ml/min, function assignable from software

Temperature
Sensor
Accuracy
Control system
Control range

From 1 to 24 units - 35x37xh36 cm
Operate interface 58x15xh48 cm with 24" monitor
PT100
0,1 °C
Measuring resident in Leonardo 3.0 software
0 - 70 °CSensor
Accuracy
Control system
Control range
Operation temperature
Pressure range

Antifoam/LevelSensor
ControlStirring
Brushless Motor
Drive
Speed (rpm)1-17001-17001-19001-18001-17000,91,1
Nominal Torque (Nm)
0,90,91,1
Impellers
Select from: Rushtons impellers, Marine impellers, Pitched blade
Thermoregulation
Control
PID Control - Accurancy 0,1 °C - Jacketed with n. 2 Electric Cartridge Heaters and cooling valve
Total heater power (W)
400
600
700
700
700
Gas Control & Gas Mixing
Sparger and overlay Gas Control
TMFC
Gas Mixing (Air, CO₂, O₂,N₂)
n.1 TMFC (included in entry level) + n.4 solenoid valves or + n. of additional TMFC (up to n.4)
Sparger type
Select from: Toro type (ring), sintered microbubbling - both provided with 0,22 μm sintered filter
Gas Out
n. 1 Condenser + 0,22 μm sinterized filter
Peristaltic Pumps
Controller
Master Control Module
HMI with Leonardo software

SensorSensitivity
Control system
Control range
Operation temperature
Pressure range

dO₂

10: n.1 Agitation Group, n.1 Gas Sparger, n.1 Gas Overlay, n.1 Gas Out/Condenser,
n.1 Sampling/Harvesting, n.1 Temperature, n.1 Multifeed, n.2 Sensors DN12, n.1 Spare
13: n.1 Agitation Group, n.1 Gas Sparger, n.1 Gas Overlay, n.1 Gas Out/Condenser,
n.1 Sampling/Harvesting, n.1 Sterile Sampling System, n.1 Temperature, n.1 Multifeed,n.2 Sensors DN12, n.3 Spare

325
425
325
425
Dimensions for autoclave (with Condenser)
Height (mm)610
705
Diameter (mm)
275
285

pH

Redox (ORP)

Digital sensor
57 to 59 mV/pH
Measuring resident in Leonardo 3.0 software
0 - 14 °C
0 - 130 °C
0 - 6 bar
Digital Optical sensor±0.05%-vol, 21±0.2%-vol, 50±0.5%-vol
Measuring resident in Leonardo 3.0 software
0,05 - 300% air saturation-10 - 130 °C
0 - 12 bar
Solaris sensor
Measuring resident in Leonardo 3.0 software

SensorSensitivity
Control system
Control range
Operation temperature
Pressure range

Digital sensor
57 to 59 mV/pH
Measuring resident in Leonardo 3.0 software± 2000 mV-10 - 130 °C≤ 6 barSensor
Accuracy
Control system
Control range
Operation temperature
Pressure range

Digital sensor±3%
Measuring resident in Leonardo 3.0 software
1 - 3000 μS/cm
0 - 130 °C
0 - 20 bar

Sensor
Accuracy
Control system
Control range
Operation temperature

Analog sensor±10% (pCO₂ 10-900 mbar) ≥ ±10% (pCO₂ > 900 mbar)
Measuring resident in Leonardo 3.0 software
0,00-200% saturation-20.0-150 °C

Conductivity

dCO₂

Cell density
Sensor
Accuracy

Control system
Pressure range
Operation temperature
Option 1Option 2Weight

Digital sensor
Mammalian cells in suspension ±5·104 cells/ml
Fermentation ±0.05 g/l dry weight
Measuring resident in Leonardo 3.0 software
0-3 bar (option 1) 0-10 bar (option 2)
0-60°C (option 1 ) 0-80°C (option 2 )(max. sterilization temperature 135°C)
Dencytee:Total cell density based on turbidity(Two ranges: 10^5 to 10^8 mammalian cells/ml - 0.5 to 100 g/L dry weight
Incyte: Viable cell density based on capacitance(Two ranges: 5x10^5 to 8x10^8 mammalian cells/ml - 5 to 200 g/L dry weight))

Sensor
AccuracyControl

Digital balance±0.2 gMeasuring resident in Leonardo 3.0 software

WM 11410-60 rpm

Peristaltic Pumps