Training Supplement Guide

Proper Shipment of Patient Specimens
and Infectious Substances

Duke University
Biological Safety Office

For questions, call 919-684-8822

Table of Contents
Shipping classification definitions…………………………………………………………….Page 3
Example list of Category A infectious substances……………………………………..Page 4
Shipping information summary table, including special provision……………Page 5
Checklist for shipping Exempt Patient Specimens(minimal likelihood that pathogens are present)……………………………………..Page 6
Checklist for shipping non-infectious specimens containing
small quantities of flammable preservative……………………………………………..Page 7
Checklist for shipping Category A, Infectious Substances….……………..........Page 8
Checklist for shipping Category B, Infectious Substances...…......................Page 9
Checklist for shipping Genetically Modified
Micro-organisms and Organisms……………………..…...…...............................Page 10
Completing the Dangerous Goods Declaration Form……………………..Pages 11 - 13
Example Packaging Diagram (PI 620 compliant)……………………………………..Page 14
Permits…………………………………………………………………………………………….…...Page 15
Department of Commerce: list of biological materials that
may require an export license………………………….………………………..…Pages 16 & 17
List of “Select Agents”……………………………………………………………………………Page 18
Manufacturers of certified shipping containers……………...........................Page 19
Classification flow chart…………………………………………………………………………Page 20

2

SHIPPING CLASSIFICATION
Exempt Patient Specimens:
Definition: Specimens collected from humans or animals including, but not limited to, excreta,secreta, blood and its components, tissue and tissue fluid swabs, and body parts being transported for
purposes such as research, diagnosis, investigational activities, disease treatment or prevention.
Exempt Patient Specimens are not assigned a Proper shipping name or UN number, as they are notfound on the List of Dangerous Goods. Consequently, they are not assigned specific packing
instructions. HOWEVER, there are minimum requirements for packing Exempt Patient Specimens in
the Dangerous Goods Regulations, and these include the use of triple packaging as detailed on page 6.
Note: If a specimen is likely or suspected to contain a human or animal pathogen, then it should be
shipped as an Infectious Substance. An element of professional judgment is required when making
such a decision. That judgment should be based on the known medical history, symptoms andindividual circumstances of the source, and endemic local conditions.

Infectious Substances:
Definition: Substances which are known or reasonably expected to contain pathogens. Pathogens aredefined as micro-organisms (including bacteria, viruses, rickettsiae, parasites, fungi) and other agents
such as prions, which can cause disease in humans or animals
1. Category A, Infectious Substances: An infectious substance which is transported in a form that,when exposure to it occurs, is capable of causing permanent disability, life-threatening or fatal
disease in otherwise healthy humans or animals. See page 4 for a list of example agents.
2. Category B, Infectious Substances: An infectious substance which does not meet the criteria
for inclusion in Category A. An example includes clinical specimens containing common
infectious microbiological organism(s).

Genetically Modified Microorganisms (GMMO) and Organisms (GMO):
Definition: Microorganisms and organisms in which genetic material has been purposely alteredthrough genetic engineering in a way that does not occur naturally

3Indicative List of Category A Infectious Substances
UN Number and Proper Shipping Name

Microorganism Classified as Category A in any Form
(Always Classified as Category A)

Microorganisms Classified as Category A only
when cultured

UN 2814 Infectious substance,
affecting humans

Crimean-Congo hemorrhagic fever virus
Ebola virus
Flexal virus
Guanarito virus
Hantaan virus
Hantavirus causing hemorrhagic fever with renal
syndrome
Hantavirus causing pulmonary syndrome
Hendra virus
Herpes B virus (Cercopithecine Herpesvirus-1)
Junin virus
Kyasanur Forest disease virus
Lassa virus
Machupo virus
Marburg virus
Monkeypox virus
Nipah virus
Omsk hemorrhagic fever virus
Russian spring-summer encephalitis virus
Sabia virus
Variola virus

UN 2900 Infectious substance,
affecting animals only

*NOTE: The list of indicative examples of Category A
Infectious substances is not exhaustive as there may be
new or emerging pathogens. If a pathogen has theability to cause permanent disability, or a lifethreatening or fatal disease in otherwise healthy
humans or animals, it must be classified as a Category A
Infectious substance.

Bacillus anthracis
Brucella abortus
Brucella melitensis
Brucella suis
Burkholderia mallei-Pseudomonas malleiGlanders
Burkholderia pseudomallei- Pseudomonas
pseudomallei
Chlamydia psittaci- avian strains
Clostridium botulinum
Coccidiodes immitis
Coxiella burnetii
Dengue virus
Eastern equine encephalitis virus
Escherichia coli, verotoxigenic
Francisella tularensis
Hepatitis B virus
Herpes B virus
Herpesvirus simiae
Human immunodeficiency virus
Human Coronavirus- Severe acute respiratory
Syndrome (SARS)
Highly pathogenic avian influenza virus
Japanese Encephalitis virus
Mycobacterium tuberculosis
Monkey B virus
Poliovirus
Rabies virus
Rickettsia prowazekii
Rickettsiae rickettsia
Rift Valley fever virus
Russian spring-summer encephalitis virus
Shigella dysenteriae type 1
Tick borne encephalitis virus
Venezuelan equine encephalitis virusWest Nile virus
Yellow Fever virus
Yersinia pestis
African swine fever virus
Avian paramyxovirus Type 1- Velogenic
Newcastle disease virus
Classical swine fever virus
Foot and mouth disease virus
Goatpox virus
Hog Cholera virus- Classical Swine Fever
Lumpy skin disease virus
Mycoplasma mycoides- Contagious bovine
pleuropneumonia
Peste de petits ruminants virus
Rinderpest virus
Sheep-pox virus
Swine vesicular disease virus
Vesicular stomatitis virus

4Shipping Information Summary
Shipment Type

Category A
infectious
substance,
affecting humans
Category A
infectious
substance,
affecting only
animals
Category B
infectious
substance
Dry Ice
Geneticallymodified microorganisms &organisms (noninfectious)
Patient Specimens(minimallikelihood that
pathogens arepresent)

ProperShipping
Name

UN
NumberInfectious
substance,
affectinghumans, (*)
Infectious
substance,
affectinganimals, (*)

UN 2814

6.2

620

Infectious
substance

UN 2900

6.2

620

Infectious
substance

Biologicalsubstance,
category B
Dry Ice
Geneticallymodifiedmicroorganisms

UN 3373

6.2

650

UN 3373

UN 1845
UN 3245

9
9

954
959

Class 9

N/A

N/A

N/A

See Checklist
on Pg.6

N/A

N/A

See Checklist
on Pg. 7

ExemptHumanSpecimen or
ExemptAnimalSpecimen
Scientificresearchspecimens,
not restricted
SpecialProvision
A180 applies

Non-infectious
N/A
specimens(mammals, birds,
amphibians,
reptiles, fish,
insect and otherinvertebrates)
containing small
quantities offlammable
preservative(*) Identify technical name of agent**Special Provisions:HazardClass

Packing
Instruction

Hazard Label

Passenger Aircraft
Max.netquantityperprimary
container

Max. net
quantity
perpackage
50ml or
50g

Cargo aircraft only
Max. net
quantityperprimary
container

50mL or
50g

1L or 4kg

4L or 4kg

1L or 4kg

Max. net
quantity
perpackageSpecialProvision
s

4L
or
4kg

A81,
A140

4L
or
4kg

A81,
A140

4L or 4kg

200kg
No Limit

200kg
No Limit

A48
A47

N/A

N/A

N/A

(flammablepreservative)30 ml/bag
1L total/outer
packaging(flammablepreservative) 30
ml/bag 1L total/outer
packaging

A180

A81 – The maximum quantity of infectious substance that can be shipped by air in one package is 4L or 4kg. The maximum quantity that may be shipped via
passenger aircraft is 50mL or 50g.
The Special Provision A81 allows the shipment of body parts, organs or whole bodies to not be restricted based on quantity limits, however the shipment must still
comply with Packing Instruction 620. Specimens transported in accordance with this Special Provision must be noted on the Shipper’s Declaration of Dangerous
Goods in the “Authorization” column of the Declaration form.
A48 – Packaging tests are not considered necessary.
A47 – Genetically modified micro-organisms and genetically modified organisms, which meet the definition of an infectious substance and the criteria for inclusion in
Division 6.2 (Category A or Category B Infectious Substances), must be transported as UN 2814, UN 2900 or UN 3373, as appropriate.
A140 – For the purposes of documentation, the proper shipping name must be supplemented with the technical name. Technical names need not be shown on the
package. When the Infectious Substances to be transported are unknown, but suspected of meeting the criteria of Category A, and assigned to UN 2814 or UN 2900,
the words “Suspected Category A Infectious Substance” must be shown in parenthesis following the proper shipping name on the Shipper’s Declaration of Dangerous
Goods, but not on outer package. A180 – Small quantities of UN 1170, UN 1198, UN 1987, or UN1219 are not subject to Dangerous Goods Regulations provided
certain packing and marking requirements are met.

5

Exempt Patient Specimens (animal or human)(Minimal likelihood that pathogens are present)

Specimen Packaging
__
__
__
__
__

Specimen in leakproof primary container
Closures of primary containers are required be held securely by secondary
means, such as adhesive tape, or friction sleeves. When it is not possible to apply
a secondary means of closure a leakproof liner must be used.
Primary containers are wrapped individually
Absorbent material sufficient to absorb entire contents of primary container(s)Leakproof secondary container (Outer containers MUST NOT be only
Styrofoam)

Labeling Outer Container
__
__
__

Statement: “Exempt human specimen” or “Exempt animal specimen”
Miscellaneous Class 9 label(2) if shipment contains dry ice, "UN 1845" andamount used in kg
Shipper and consignee details should be on the same surface of the packagenear the proper shipping name marking, if the package dimensions areadequate.

Completing the Airbill
__
__
__
__
__

Name and address of shipper and recipient
Check “Saturday Delivery” box if applicable
In Section 6 (Special Handling) of the airbill, indicate that the shipment is NOT adangerous good
Check the “Dry Ice” box if applicable and indicate “UN 1845” and the quantity ofdry ice in kg
Shipper’s signature (optional)

Note: When determining whether a patient specimen has a minimal likelihood that
pathogens are present, an element of professional judgment is required. That judgment
should be based on the known medical history, symptoms and individual circumstancesof the source and endemic local conditions.

6Non-infectious Specimens

containing small quantities offlammable preservative in the following categories:

UN 1170 (Ethanol, Ethanol solution),UN 1198 (Formalin, Formaldehyde solution),
UN 1987 (Alcohols, n.o.s.*) or
UN 1219 (Isopropyl alcohol, Isopropanol)
Specimen Packaging____

Wrapped in paper towel and/or cheesecloth moistened with alcohol or an
alcohol solution and then placed in a plastic bag that is heat-sealed. Any freeliquid in the bag must not exceed 30 mL OR
Placed in vials or other rigid containers with no more than 30 mL of alcohol or an
alcohol solution__

Prepared specimens are then placed in a plastic bag that is then heat-sealed__

The bagged specimens are then placed inside a another plastic bag withabsorbent material then heat-sealed__

The finished bag is then placed in a strong outer packaging(Styrofoam must be in an outer cardboard box) with suitable cushioning
material__

The total quantity of flammable liquid per outer packaging must not exceed 1 L

Labeling Outer Container__
The completed package is marked “scientific research specimens, not restricted
Special Provision A180 applies”
Completing the Airbill__ The words “not restricted" and the special provision number A180 must be includedin the description of the substance on the Air Waybill as required by 8.2.6, when an Air
Waybill is issued.

*Not otherwise specified

7

Category A Infectious Substances
Packing Instruction (PI) 620

Specimen Packaging (primary or secondary is pressure and drop test approved: see PI 620)
__
__
__
__
__
__

Specimen in leakproof primary container
Closures of primary containers are required be held securely by secondary
means, such as adhesive tape or friction sleeves. When it is not possible to apply
a secondary means of closure a leakproof liner must be used.
Primary containers are wrapped individually
Absorbent material sufficient to absorb entire contents of primary container(s)Leakproof secondary container
Itemized list of contents placed between secondary and outer container

Labeling Outer Container
__
__
__
__
__
__

Infectious Substance, Class 6 label“Infectious Substance Affecting Humans”, “UN 2814” or “Infectious Substance
Affecting Animals, “UN 2900” and net quantity of infectious substance
Miscellaneous Class 9 label if shipment contains dry ice, “UN 1845” and amountused in kg
Name and telephone number of the responsible party, knowledgeable of the
package contents and available 24 hours a day
If shipment includes >50mL or 50g of a Category A infectious substance, thenadd a “Danger, do not load in passenger aircraft” label to the outer container
Shipper and consignee details should be on the same surface of the packagenear the proper shipping name marking, if the package dimensions areadequate.

Dangerous Goods Declaration Form*
__
__
__
__

Name, address and phone number of shipper and recipientMark out non-applicable “Aircraft Box”
Mark out non-applicable “Radioactive” box
24-hour emergency response telephone number for the responsible party,
knowledgeable of the package contents in the “Handling Information” box__
Name and title of signatory, place, and date__
Shipper’s signature*49 CFR 172.201 (e): The shipper MUST retain a copy of the Shipper's Declaration for aminimum of 2 years.
“Nature and Quantity of Dangerous Goods” section of the Declaration Form__
Complete this section using the information provided on Pages 5, 11 & 12 of this
Guide

8

Category B Infectious Substances
Packing Instructions (PI) 650

Specimen Packaging (primary or secondary is pressure and drop test approved: see PI 650)
__
__
__
__
__
__

Specimen in leakproof primary container
Closures of primary containers are required be held securely by secondary
means, such as adhesive tape or friction sleeves. When it is not possible to apply
a secondary means of closure a leakproof liner must be used.
Primary containers are wrapped individually
Absorbent material is sufficient to absorb entire contents of primary container(s)Leakproof secondary container
Itemized list of contents placed between secondary and outer container

Labeling Outer Container
__
__
__
__

UN 3373 label(1)Statement: “Biological Substance, Category B” adjacent to UN 3373 label
Miscellaneous Class 9 label(2) if shipment contains dry ice, "UN 1845" andamount used in kg
Shipper and consignee details should be on the same surface of the packagenear the proper shipping name marking, if the package dimensions areadequate.

Completing the Airbill
__
__
__
__
__

(1) -

Name and address of shipper and recipient
Check “Saturday Delivery” box if applicable
In Section 6 (Special Handling) of the airbill, indicate that the shipment is adangerous good, which does NOT require a Shipper’s Declaration
Check the “Dry Ice” box if applicable and indicate “UN 1845” and the quantity ofdry ice in kg
Shipper’s signature (optional)

(2) -

9

Genetically Modified Micro-organisms & Organisms

Note: If a GMMO or GMO is a Category A or Category B Infectious Substance,
package the material accordingly.

Specimen Packaging
__
__
__
__
__
__

Specimen in leakproof primary container
Closures of primary containers are required be held securely by secondary
means, such as adhesive tape or friction sleeves. When it is not possible to apply
a secondary means of closure a leakproof liner must be used.
Absorbent material is sufficient to absorb entire contents of primary container(s)Primary containers are wrapped individually
Leakproof secondary container
Itemized list of contents placed between secondary and outer container

Labeling Outer Container
__
__
__
__

Miscellaneous Class 9 label“Genetically modified micro-organism” or “Genetically modified organism”,“UN 3245(3) ”
If shipment contains dry ice, “UN 1845” and amount used in kg
Shipper and consignee details should be on the same surface of the packagenear the proper shipping name marking, if the package dimensions areadequate.

Dangerous Goods Declaration Form (if required)
__
__
__
__

Name, address and phone number of shipper and recipientMark out non-applicable “Aircraft Box”
Mark out non-applicable “Radioactive” box
24-hour emergency response telephone number for the responsible party,
knowledgeable of the package contents__
Name and title of signatory, place, and date__
Shipper’s signature“Nature and Quantity of Dangerous Goods” section of the Declaration Form__
Complete this section using the information provided on Pages 5, 11 & 12 of thisguide.

(3) -10

Completing the Top-half of a Dangerous Goods Declaration* FedEx Express® dangerous goods shipments originating in the U.S. musthave the Shippers’ Declarations prepared using one of the following
methods:• FedEx-approved vendor software application• Pre-approved shipper proprietary software• FedEx Express Automated Shipping Solutions that have dangerous goods error
checksA – Shipper: Enter your full name, address and telephone number.
B – Consignee: Enter full name and address of recipient. When shipping infectious
substances, include the text, “Person responsible:” plus his/her name and phone
number at the bottom of “Consignee” box.
C – Transport Details: Indicate here if your shipment is restricted to cargo aircraft only
(if it is > 50ml or 50g of an infectious substance). Airport of departure and airport ofdestination will be filled out by the carrier, leave blank.
D – Shipment Type: Cross out “radioactive” to indicate you are shipping a nonradioactive substance.

11Completing the Bottom-half of a Dangerous Goods Declaration

E – UN or ID Number: Enter appropriate UN number (i.e. UN 2814 or UN 2900).
F – Proper Shipping Name: Enter the proper shipping name with the technical name inparentheses – i.e. “Infectious substance, affecting humans (Hepatitis B virus)”. UN 2814
or UN 2900 that is suspected to contain an unknown Category A infectious substancemust have the words ‘‘suspected Category A infectious substance’’ next to the Proper
Shipping Name.
G – Class or Division: Enter appropriate hazard class (i.e. 6.2 or 9).
H – Packing Group: For dry ice, enter “III” in this column. Biological materials are notassigned packing groups.
I – Quantity and Type of Packaging: Enter the net quantity for each material here. Use
only metric units. At the bottom of this column, indicate the number and type of
packages. If multiple packages are packed in one overpak state (“All packed in one
fibreboard box.”). Do not spell like “fiberboard.” If using an overpack, indicate here with
“Overpack Used.”12Completing the Bottom-half of a Dangerous Goods Declaration

J – Packing Instructions: Enter appropriate packing instruction number. The Packing
Instruction for infectious substances is 620. The Packing Instruction for dry ice is 954.
K – Authorization: Note any Special Provisions, if applicable (i.e. if you choose to notinclude the technical name on outer package, you must list A140 in this column).
L – Additional Handling Instructions: The statement “Emergency Contact:” followed bya 24-hour emergency telephone response number where the shipper can be reached.
M – Sign and date each copy of your Shipper’s Declaration.
** A statement must appear on the Shipper’s Declaration. The statement reads asfollows: “I declare that all of the applicable air transport requirements have beenmet.” This statement is often pre-printed on the form (see above). If this statement
does not appear on the form then it should be typed in the “Additional Handling”
section of the form.

13

Packed in Compliance with IATA Packing Instruction 620(Category A Infectious Substances)

Closure sealing tape

Proper shipping name, UN#
and amount of material

UN packaging specification markings(IATA 6.0.6)

Note: Shipments that include > 50mL or 50g of Category A Infectious
Substances, must have this label attached to the outer container.

14

Does your shipment need a permit?
If yes or you are unsure, contact the Duke University Office of Export Controls
http://ors.duke.edu/export-controls (919-668-2711). Import Permit assistance is also
provided.
CDC Import Permit:••

Is required if you import:o any etiologic agento any arthropod or other animal host or vector of human diseaseo any exotic living arthropod or other animal capable of being a host or
vector of human disease
CDC: Etiologic Agent Import Permit Program
o Website: http://www.cdc.gov/od/eaipp/o Telephone: 404-498-2260; FAX: 404-498-2275
o Permit Application:
http://www.cdc.gov/od/eaipp/importApplicationForms.htm

USDA/ APHIS Permit:••

May be required for all imports/ exports, and inter-state transport of:o animal or plant pathogens
o specimens reasonably believed to contain animal or plant pathogens
o any pest or vector of animal or plant diseaseo potentially hazardous animal or plant products
APHIS: Import and Exporto http://www.aphis.usda.gov/import_export/index.shtml
o Telephone: 301-734-0841(plants), 301-734-3277 (animals)

Department of Commerce (DOC) Export License:•••

May be required when exporting:o infectious agents of human, plant and animal diseaseso genetic material, and products which might be used for culture of large
amounts of agents
DOC: Bureau of Industry and Security (BIS):o Website: http://www.bis.doc.gov/index.htm
o Telephone: 202-482-4811
Review list of biological materials which may require an export license on pages
16 and 17 of this guide.

15

List of Biological Materials that MAY Require a DOC Export License
HUMAN PATHOGENS AND TOXINSBacteria• Bacillus anthracis• Brucella abortus• Brucella melitensis• Brucella suis
• Burkholderia mallei (Pseudomonas mallei)• Burkholderia pseudomallei (Pseudomonas
pseudomallei)• Chlamydia psittaci• Clostridium botulinum• Clostrium perfringens, epsilon toxin
producing types• Enterohaemorrhagic Escherichia coli,
serotype O157 and other verotoxin
producing serotypes• Francisella tuarensis• Salmonella typhi• Shigella dysenteriae• Vibrio cholerae• Yersinia pestis
Toxins
•
•
•
•
•
•
•
•
•
•
•
•
•
•
•
•
•
•
•

Abrin
Aflatoxins
Botulinum toxins
Cholera toxin
Clostridium perfringens toxin
Conotoxin
Diacetoxyscirpenol toxin
HT-2 toxin
Microcystin (Cyanginosin)
Modeccin toxin
Ricin
Saxitoxin
Shiga toxin
Staphylococcal aureus toxins
T-2 toxin
Tetrodotoxin
Verotoxin
Volkensin toxin
Viscum albumin lectin 1 (Viscumin)

Viruses• Chikungunya virus• Congo-Crimean haemorrhagic fever virus• Dengue fever virus• Eastern equine encephalitis virus• Ebola virus• Hantaan virus• Hendra virus (Equine morbillivirus)• Japanese encephalitis virus• Junin virus• Kyasanur forest virus• Lassa fever virus• Louping ill virus• Lymphocytic choriomeningitis virus• Machupo virus• Marburg virus• Monkeypox virus• Murray Valley encephalitis virus• Nipah Virus• Omsk haemorrhagic fever virus• Oropouche virus• Powassan virus• Pulmonary and renal syndromehaemorrhagic fever viruses (Seoul,
Dobrava, Puumala, Sin Nombre)• Rabies virus cultures• Rift Valley fever virus cultures• Rocio virus• South American haemorrhagic fever virus(Sabia, Flexal, Guanarito)• St. Louis encephalitis virus• Tick-bourne encephalitis virus (Russian
Spring-Summer encephalitis virus)• Variola virus• Venezuelan equine encephalitis virus
cultures• Western equine encephalitis virus• White pox virus• Yellow fever virus
Rickettsiae• Bartonella quintana (Rochalimea quintana,
Rickettsia quintana)• Coxiella burnetii• Rickettsia prowasecki• Rickettsia rickettsii

16

List of Biological Materials that MAY Require a DOC Export License – Continued
ANIMAL PATHOGENS AND TOXINSBacteria• Mycoplasma mycoides
Viruses• African horse sickness virus• African swine fever virus• Avian influenza virus (highly pathogenic
strains• Bluetongue virus• Foot and mouth disease virus• Goat pox virus• Lumpy skin disease virus• Lyssa virus

Viruses continued• Newcastle disease virus• Peste des petis ruminants virus• Porine enterovirus type 9 (Swine vesiculardisease virus)• Porcine herpes virus (Aujeszky’s disease)• Rinderpest virus• Sheep pox virus• Swine fever virus (Hog cholera virus)• Teschen disease virus• Vesicular stomatitis virus

PLANT PATHOGENS
Bacteria• Xanthomonas albilineans• Xanthomonas campestris pv. citri types A,
B, C, D, E or otherwise classified as X. citri,
X campestris pv. aurantifolia or X.
campestris pv. Citrumelo• Xanthomonas oryzae• Clavibacter michiganenis subspecies
sepedonicus• Ralstonia solanacearum Races 2 & 3

Fungi
•

Viruses• Potato Andean latent tymovirus• Potato spindle tuber viroid

•
•
•
•
•

Colletotrichum coffeanum var. virulans (C.
kahawae)
Coochliobolus miyabeanus(Helminthosporium oryzae)
Magnaporthe grisea (pyricularia grisea/
pyricularia oryzae)
Microcyclus ulei (Dothidella ulet)
Puccinia graminis (Puccinia graminis f. sp.
tritici)
Puccinia striformis (Puccinia glumarum)

GENETIC ELEMENTS/GENETICALLY MODIFIED ORGANISMS
•
•
•
•
•

Genetic elements that contain nucleic acid sequences associated with the pathogenicity ofcontrolled microorganisms.
Genetic elements that contain nucleic acid sequences coding for any controlled “toxins” or “subunits of toxins”.
Technical Note: Genetic elements include, inter alia, chromosomes, genomes, plasmids,
transposons, and vectors, whether genetically modified or unmodified.
Genetically modified organisms that contain nucleic acid sequences associated with thepathogenicity of controlled microorganisms.
Genetically modified organisms that contain nucleic acid sequences coding for any controlled“toxins” or “sub-units of toxins”.

17Contact Biological Safety at 919-684-8822 prior to Shipment or Receipt of the following:18

Manufacturers of Certified Shipping Containers for Infectious Substances,
Patient Specimens & Dry Ice

Air Sea Atlanta
1234 Logan Circle
Atlanta, GA 30318
Phone: 404-351-8600
www.airseaatlanta.com

Berlin Packaging
1195 Washington Pike
Bridgeville, PA 15017
Phone: 800-2-BERLIN

Inmark, Inc.
675 Hartman Road, Suite 100
Austell, GA 30168
Phone: 800-646-6275
www.inmarkinc.com

SAF-T-PAK, Inc.
899 Airport Park Rd Ste A
Glen Burnie, MD
21061-2557
Phone: 800-814-7484
www.saftpak.com.
FedEx-recognized shipper’s
declaration available at the“On-line Forms/Shipper’s
Declaration” link:(http://www.saftpak.com/Su
pport/Support.aspx).

ThermoSafe
3930 N. Ventura Drive
Arlington Heights, IL 60004
Phone: 800-323-7442
www.thermosafe.com

www.berlinpackaging.com/

CARGOpak Corporation
PO Box 98686
Raleigh, NC 27615
Phone: 800-266-0652
www.cargopak.com

Therapak Corporation
4305 Hamilton Mill Road
Suite 200
Buford, Georgia 30518
Phone: 888-505-7377
www.therapak.com

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