(２０１０年)
1. Nagayama Y. Observations on the proposed “nonclassical” model ofautoimmune hypothyroidism. Thyroid. 20 (6): 665-666, 2010.
2. Nakahara M, Mitsutake N, Sakamoto H, Ichiakwa T, Abiru N, Chen C-R,
Rapoport B, McLachlan SM, Nagayama Y. Enhanced response to mousethyrotropin (TSH) receptor immunization in TSH knockout mice. Endocrinology.
151 (8): 4047-4054, 2010.
3. Chen C-R, Hamidi S, Braley-Mullen H, Nagayama Y, Bresee CMS, Rapoport B,McLachlan SM. Antibodies to thyroid peroxidase arise spontaneously with age inNOD.H-2h4 mice but are not associated with experimentally induced thyroiditis.
Endocrinology. 151 (9): 4583-4593, 2010.

(２０１１年)
1. Nagayama Y. Animal models of autoimmune thyroid disease. (In)Immunoendocrinology: Scientific and Clinical Aspects. Eisenbarth G (ed),Humana Press, pp.415-426, 2011.
2. Taira Y, Hayashida N, Brahmanandhan GM, Nagayama Y, Yamashita S,
Takahashi J, Gutevitc A, Kozlovsky A, Urazalin M, Takamura N. Current
concentration of artificial radionuclides and estimated radiation doses around theChernobyl Nuclear Power Plant, the Semipalatinsk Nuclear Testing Site, and inNagasaki. J Radiat Res. 52 (1): 88-95, 2011.
3. Ueki I, Abiru N, Kobayashi M, Nakahara M, Ichikawa T, Kerley, Eguchi K,Nagayama Y. B Cell-Targeted Therapy with anti-CD20 monoclonal antibody in amouse model of Graves’ Hyperthyroidism. Clin Exp Immunol. 163(3):309-317,2011.
4. Horie I, Abiru N, Saitoh O, Ichikawa T, Iwakura Y, Eguchi K, Nagayama Y.
Distinct role of T helper type 17 immune response for Graves’ hyperthyroidism inmice with distinct genetic backgrounds. Autoimmunity. 44(2):159-165, 2011.
5. Suzuki K, Mitsutake N, Saenko V, Matsuse M, Ohtsuru A, Kumagai A, Uga T,Yano H, Nagayama Y, Yamashita S. Dedifferentiation of human primary thyrocytes
into multilineage progenitor cells without gene introduction. PLoS ONE. 6(4) :e19354, 2011.
6. Ueki I, Abiru N, Kawagoe K, Nagayama Y. IL-10 deficiency attenuates inductionof anti-thyrotropin receptor antibodies and hyperthyroidism in a mouse Graves’model. J Endocrinol. 209 (3): 353-357, 2011.

7. Nakahara M, Nagayama Y, Ichikawa T, Liping Yu, George S. Eisenbarth, Abiru
N. The effect of Regulatory T cell depletion on the spectrum of organ-specificautoimmune diseases in non-obese diabetic mice at different ages. Autoimmunity.
44 (6): 504-510, 2011.
8. Horie I, Abiru N, Sakamoto H, Iwakura Y, Nagayama Y. Induction ofautoimmune thyroiditis by depletion of CD4+CD25+ regulatory T cells inthyroiditis-resistant IL-17, but not interferon-gamma receptor, knockout
nonobese diabetic-H2h4 mice. Endocrinology. 152 (11): 4448-4454, 2011.
9. Satoh T, Abiru N, Kobayashi M, Zhou H, Nakamura K, Kuriya G, Nagayama Y,Kawasaki E, Yamasaki H, Yu L, Eisenbarth GS, Araki E, Mori M, Oyadomari S,Eguchi K. CHOP deletion does not impact the development of diabetes but
suppresses the early production of insulin autoantibody in the NOD mouse.
Apoptosis. 16 (4): 438-448, 2011.

(２０１２年)
1. Nagayama Y, Nakahara M, Shimamura M, Horie I, Arima K, Abiru N.
Prophylactic and therapeutic efficacies of a selective inhibitor of theimmunoproteasome for Hashimoto's thyroiditis, but not for Graves'
hyperthyroidism in mice. Clin Exp Immunol.168 (3): 268-273, 2012.
2. Nakahara M, Johnson K, Eckstein A, Yamada N, Taguchi R, Abiru N, Nagayama
Y. Adoptive transfer of antithyrotropin receptor (TSHR) autoimmunity from TSHR
knockout mice to athymic nude mice. Endocrinology. 153 (4): 2034-2042, 2012.

(２０１３年)
1. Johnson KTM, Ziler B, Schott M, Muller M, Minich WB, Nagayama Y, Gulbins E,Eckstein AK, Berchner-Pfannschmidt U. Examination of Orbital Tissues in Murine
Models of Graves' Disease reveals expression of UCP-1 and the TSHR in
retrobulbar adipose tissues. Hor Metb Res. 45 (6): 401-407, 2013.
2. Kobayashi M, Kaneko-koike C, Abiru N, Uchida T, Akazawa S, Nakamura K,Kuriya G, Satoh T, Ida H, Kawasaki E, Yamasaki H, Nagayama Y, Sasak H,Kawakami A. Genetic deletion of Granzyme B does not confer resistance to thedevelopment of spontaneous diabetes in NOD mice. Clin Exp Immunol. 173(3):411-418,2013

3. Kashiyama K, Nakazawa Y, Shimada M, Sasaki K, Takahashi Y, Fawxett H, Lewin
SO, Carr L, Yoshida K, Utani A, Hirano A, Yamashita S, Nagayama Y, Mitsutake N,Lehmann AR, Ogi T. Identification of new Cockayne syndrome patients deficientin the ERCC1 and XPF/ERCC4 gene. Am J Hum Gnenet. 92 (5):807-819, 2013.
4. Kuriya G, Abiru N, Kobayashi M, Nagayama Y, Akazawa S, Nakamura K, SatoT, Horie I, Kuwahara H, Kawasaki E, Yamasaki H, Yu L, Eisenbarth GS, Iwakura Y,Eguchi K. Double deficiency in IL-17 and IFN-g signaling significantly suppresses
the development of diabetes in the NOD mouse. Diabetologia. 56 (8):1773-1780,2013.
5．Yasui K, Shimamura M, Mitsutake N, Nagayama Y. SNAIL Induces Epithelialto-Mesenchymal Transition but not Cancer Stem Cell-like Properties in Thyroid
Cancer. Thyroid. 23 (8):989-996, 2013.

(２０１４年)
1. Orim F, Bychkov A, Shimamura M, Nakashima M, Mito M, Bogdanova T, Matsuse
M, Suzuki K, Saenko V, Nagayama Y, Yamashita S, Mitsutake N. Thyrotropin
signaling confers more aggressive features with higher genomic instability on
BRAFV600E-induced thyroid tumors in a mice model. Thyroid. 24(3):502-510,
2014.
2. Shimamura M, Nakahara M, Kurashige T, Yasui K, Nakashima M, Nagayama Y.
Disruption of transforming growth factor-b signaling in thyroid follicular epithelialcells or intrathyroidal fibroblasts does not promote thyroid carcinogenesis.
Endocrine J. 61(3):297-302, 2014.
3. Shimamura M, Nagayama Y, Matsuse M, Yamashita S, Mitsutake N. Analysis ofmultiple markers for cancer stem-like cells in human thyroid carcinoma cell lines.
Endocrine J. 61 (15): 481-490, 2014.
4. Yasui J, Nakahara M, Shimamura M, Kurashige T, Yasui K, Abiru N, Kawakami
A, Nagayama Y. Minor contribution of cytotoxic T lymphocyte antigen 4 andprogrammed cell death 1 ligand 1 in immune tolerance against mouse thyrotropin
receptor in mice. Acta Med Nagasaki. 59 (1): 13-17, 2014.

(２０１５年)
1. Kurashige T, Shimamura M, Yasui K, Mitsutake N, Matsuse M, Nakashima M,

Minami S, Eguchi S, Nagayama Y. Expression of aldehyde dehydrogenase innormal and cancerous tissues of thyroids. Horm Metab Res.47 (3): 194-199, 2015.
2. Jia N, Nakazawa Y, Guo C, Shimada M, Sethi M, Takahashi Y, Ueda H, Nagayama
Y, Ogi T. A rapid, comprehensive system for assaying DNA repair activity andcytotoxic effects of DNA-damaging reagents. Nat Protcol. 10(1):12-24, 2015.
3. Nakashima M, Shimamura M, Yasui K, Mitsutake N, Matsuu-Matsuyama M,Matsuda K, Nagayama Y. Cancer stem cell theory and intratumor heterogeneity
in thyroid carcinogenesis. J Basic Clin Med. 4(1): 8-12, 2015.
4. Nagayama Y, Nakahara M, Abiru N. Animal models of Graves’ disease andGraves’ orbitopathy. Curr Opin Endocrinol Diabetes Obes. 22 (5): 381-386. 2015.
5. Akazawa S, Kobayashi K, Kuriya G, Horie I, Yu L, Yamasaki H, Okita
M,Nagayama Y, Matsuyama T, Akbari M, Yui K, Kawakami A, Abiru N.
Haploinsufficiency of interferon regulatory factor 4 strongly protects against
autoimmune diabetes in non-obese diabetic mice. Diabetologia, 58 (11): 26062014. 2015.
6. Matsuu-Matsuyama M, Shichijo K, Okaichi K, Kurashige T, Kondo H, Miura S,Nakashima M.Effect of age on the sensitivity of the rat thyroid gland to ionizing
radiation.J Radiat Res. 56(3):493-501, 2015.
7. Miura S, Akazawa Y, Kurashige T, Tukasaki K, Kondo H, Yokota K, Mine M,Miyazaki Y, Sekine I, Nakashima M.The Nagasaki Atomic Bomb Survivors' Tumor
Tissue Bank. Lancet. 2015 386(10005):1738, 2015.

（２０１６年）
A 欧文A-a
1. Kurashige T, Shimamura M, Nagayama Y: Differences in quantification of DNA
double strand breaks between 53BP1/γH2AX focus formation assays and thecomet assay in mammalian cells treated with irradiation and N-acetyl-L-cysteine.
J Radiat Res.
57: 312-317, 2016. (IF: 1.536)
2. Nikitski A, Saenko V, Shimamura M, Nakashima M, Matsuse M, Suzuki K,Rogounovitch T, Bogdanova T, Shibusawa N,Yamada M, Nagayama Y, Yamashita
S, Mitsutake N : Targeted Foxe1 overexpression in mouse thyroid causes thedevelopment of multinodular goiter but does not induce carcinogenesis.
Endocrinology. 157(5):2182-2195, 2016. (IF: 4.159)
3. Shimamura M, Kurashige T, Mitsutake N, Nagayama Y: Role of aldehydedehydrogenase 1A3 for cancer stem properties of anaplastic thyroid cancer celllines. Endocrine, in press.2017. (IF: 3.279)
4. Yoshida K, Sinkawa T, Urata H, Nakashima K, Orita M, Yasui K, Kumagai A,Ohtsuru A, Yabe Y, Maeda M, Hayashida N, Kudo T, Yamashita S, Takamura N.：
Psychological Distress of Residents in Kawauchi Village, Fukushima Prefecture
After the Accident at Fukushima Daiichi Nuclear Power Station: The Fukushima
Health Management Survey. Peer J 4:e2353, 2016
(IF: 2.183)
A-b
1. Nagayama Y, Shimamura M, Mitsutake N: Cancer stem cells in the thyroid.
Frontiers in Endocrinology, section Thyroid Endocrinology. 7:20, 2016.
A-c
1. Nagayama Y. TSH receptor. In Biomedical Sciences (Elsevier) in press.
B 邦文
B-a
1. 吉田浩二、新川哲子、浦田秀子、林田直美、矢部博興、前田正治、大津留晶、高村昇：東日本大震災後の福島県川内村住民の生活習慣と精神健康度評価．福島県県民健康調査． 長
崎医学会雑誌 91 巻特集号：224-226，2016
2. 徳 永 瑛 子 、岩 永 竜 一 郎 、大 石 和 代 、花 田 裕 子 、森 藤 香 奈 子 、山本 直 子 、折 田 真 紀 子 、吉 田 浩 二 、井口茂、浦田秀子、前田正治、大津留晶、矢部博興、松坂誠應、田中悟郎、中根秀之：東日本大震災後の子ども達への影響～子どもの強さと困難さ尺度 (SDQ)を用いて～． 長崎医学会雑誌 91 巻特集号 ：227-229,2016
3. 森 藤 香 奈 子 、大 石 和 代 、花 田 裕 子 、山 本 直 子 、折 田 真 紀 子 、徳永 瑛 子 、岩 永 竜 一 郎 、吉 田 浩 二 、井口茂、浦田秀子、大津留晶、矢部博興、松坂誠應、田中悟郎、中根秀之：福島県川内村における子育て世代の抱える多重ストレスに関する質的研究．長崎医学会雑雑誌 91 巻特集号：230-233,2016

4. 山口拓允、新川哲子、浦田秀子、吉田浩二、永田明、高村昇：看護学生における放射線に関する知識とイメージ調査． 長崎医学会雑誌 91 巻特集号：237-240,2016
B-b
1. 永山雄二：TSH receptor．医学のあゆみ．256 (5): 503-508, 2016.
2. 永山雄二：甲状腺刺激ホルモン受容体とバセドウ病．長崎市医師会報. 50 (5): 23-27,
2016.
B-e
1. 吉田浩二, 新川哲子, 浦田秀子：福島第一原子力発電所事故後の福島県内保健師の精神ストレスの調査．日本看護研究学会雑誌 39 (3): 143, 2016
2. 田浩二, 新川哲子, 浦田秀子, 高村昇：福島県内保健師が抱く住民からの放射線に関連した質問対応への不安の分析．第 5 回日本放射線看護学会学術集会 抄録集 55, 2016
3. 浦田秀子、新川哲子、吉田浩二、折田真紀子、今村圭子、佐藤良信、金丸由美子、田中準一、永田明、林田直美、高村昇： 放射線の健康影響に係る研究事業「福島県川内村の帰村促進のための取り組み」成 果報告会の実施：第 5 回日本放射線看護学会学術集会抄録集68,2016
4. 新川哲子、浦田秀子、吉田浩二、折田真紀子、永田明、金丸由美子、田中準一、高村昇、林田直美、佐藤良信： 被ばく医療に強い高度医療人育成の為の放射線看護教育長崎モデル．
第 5 回日本放射線看護学会学術集会抄録集 57,2016
5. 山口拓允、新川哲子、折田真紀子、吉田浩二、浦田秀子、高村昇： 大学生による復興子ども教室の活動報告と今後の課題．第 5 回日本放射線看護学会学術集会抄録集 77,2016